Document Document Title
US09938538B2 Fertility gene and use thereof
The present disclosure relates to a fertility gene and the use thereof, and relates to the biotechnology field, particularly to a method of plant hybrid breeding including creation of a sterile line and preparation of hybrid seeds, more particularly to a fertility gene FL2, a mutant thereof and use thereof in hybrid breeding.
US09938535B2 Medicago truncatula gene-regulatory elements and uses thereof
Recombinant DNA molecules and constructs useful for modulating gene expression in plants, including molecules derived from Medicago truncatula sequences, are provided. Transgenic plants, plant cells, plant parts, and seeds comprising recombinant DNA molecules operably linked to heterologous transcribable DNA molecules are further provided, as are methods of their use.
US09938532B2 Molecules inhibiting the human immunodeficiency virus type 1 (HIV-1), method for the production thereof and applications of same
The invention relates to an aptamer, the structure thereof comprising at least one nucleotide sequence 5′-GGCA(A/G)GGA-3′, that can specifically bind to the poly(A) hairpin of the 5′UTR region of the genome of the human immunodeficiency virus type 1 (HIV-1), providing the method for producing aptamers with said sequence by means of a combination of experimental techniques of in vitro selection of nucleic acids with computational techniques of sequence optimization. The invention also relates to a DNA gene structure for synthesizing said aptamers, preferably RNA. The invention further relates to the different uses of the above-mentioned aptamer, including the use thereof as a biosensor molecule for detecting and/or quantifying HIV-1, as an inhibitor of the production of viral particles of HIV-1, and to the application thereof in medicine, the invention also relating to a method for treating a disease caused by HIV-1, and to a pharmaceutical composition comprising said aptamer.
US09938531B2 Compositions and methods for inhibiting expression of RRM2 genes
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a RRM2 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a RRM2 gene using said pharmaceutical composition; and methods for inhibiting the expression of RRM2 in a cell.
US09938528B2 Methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections
The present invention provides methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections. In particular, the present invention relates to a method for treating HIV-1 infection in a subject in need thereof comprising administering the subject with a therapeutically effective amount of an inhibitor of SGT1 activity or expression.
US09938527B2 Potent LNA oligonucleotides for the inhibition of HIF-1A expression
The present disclosure relates to an LNA oligonucleotide consisting of a sequence selected from the group consisting of 5′-(Tx)GxGxcsasasgscsastscscsTxGxT-3′ and 5′-(Gx)TxTxascstsgscscststscsTxTxA-3′, wherein capital letters designate a beta-D-oxy-LNA nucleotide analog, small letters designate a 2-deoxynucleotide, underline designates either a beta-D-oxy-LNA nucleotide analog or a 2-deoxynucleotide, subscript “s” designates a phosphorothioate link between neighboring nucleotides/LNA nucleotide analogs, and subscript “x” designates either a phosphorothioate link or a phosphorodiester link between neighboring nucleotides/LNA nucleotide analogs, and wherein the sequence is optionally extended by up to five 2-deoxynucleotide units. The LNA oligonucleotides are useful for modulating the expression of hypoxia-inducible factor-1a (HIF-1a), e.g. in the treatment of cancer diseases, inhibiting angiogenesis, inducing apoptosis, preventing cellular proliferation, or treating an angiogenic disease, e.g. diabetic retinopathy, macular degeneration (ARMD), psoriasis, rheumatoid arthritis and other inflammatory diseases.
US09938524B2 Multiplex isolation of protein-associated nucleic acids
The invention provides novel methods and materials for genetic and genomic analysis using single or multiplex isolation of protein-associated nucleic acids, including transposase-assisted chromatin immunoprecipitation (TAM-ChIP) and antibody-oligonucleotide proximity ligation. These methods comprise tagging and isolating chromatin or other protein-associated nucleic acids and using antibody-oligonucleotide complexes that recognize the proteins associated with such nucleic acids.
US09938519B2 Methods and systems for DNA isolation on a microfluidic device
The present invention relates to methods and systems for the isolation of DNA on a microfluidic device and the subsequent analysis of the DNA on the microfluidic device. More specifically, embodiments of the present invention relate to methods and systems for the isolation of DNA from patient samples on a microfluidic device and use of the DNA for performing amplification reactions, such as PCR, and detection, such as thermal melt analysis, on the microfluidic.
US09938518B2 Organic devices for the photoinhibition of excitable cells
Devices are provided for inhibiting the electrical activity of an excitable cell through the application of a pulse of light which includes a substrate and a photoreactive film both of non-conducting material and laid directly on one another, in which the photoreactive film includes a layer of semiconductor polymer material and has an interface surface which can be placed in contact with an excitable cell and an electrolyte solution. After absorbing light, when placed in contact with the excitable cell and the electrolyte solution, the photoreactive film produces a potential difference across this interface surface which is capable of giving rise to hyperpolarization of the membrane of the excitable cell. Methods of inhibiting the electrical activity of excitable cells using such devices are also provided.
US09938517B2 Small enzyme-containing granules
The invention provides small enzyme-containing granules having an inorganic salt core and an enzyme-containing layer coated over the core, and methods for producing such granules. The majority of the enzyme granules are less than 300 μm in diameter. The granules are suitable for incorporation into compositions such as cleaning, textile processing, and animal feed compositions.
US09938511B2 Enzymes
The invention relates to a nucleic acid polymerase capable of producing a non-DNA nucleotide polymer from a DNA nucleotide template, said polymerase comprising amino acid sequence having at least 36% identity to the amino acid sequence of SEQ ID NO:1, wherein said amino acid sequence is mutated relative to the amino acid sequence of SEQ ID NO:1 at one or more residues of the thumb region, said residues selected from: amino acids 651 to 679 (patch 10A); wherein said amino acid sequence is mutated relative to the amino acid sequence of SEQ ID NO:1 at residue E664. In one embodiment said polymerase comprises the mutations Y409G and E664K. In one embodiment said polymerase comprises amino acid sequence corresponding to SEQ ID NO:12. The invention also relates to A nucleic acid polymerase capable of reverse transcribing a HNA nucleotide polymer into a DNA nucleotide polymer, said polymerase comprising amino acid sequence having at least 36% identity to the amino acid sequence of sEQ ID NO:1, wherein said amino acid sequence is mutated relative to the amino acid sequence of SEQ ID NO:1 at residue I521.
US09938509B2 Biocatalysts and methods for the synthesis of armodafinil
The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (−)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
US09938507B2 Methods of propagating rhinovirus C in previously unsusceptible cell lines
The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
US09938504B2 Method for producing induced pluripotent stem cell from mesenchymal stem cell and induced pluripotent stem cell produced by the method
The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for producing induced pluripotent stem cells using the medium composition. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced safely, easily, and efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into a variety of cells.
US09938503B2 Differentiation of human iPS cells to human alveolar type II via definitive endoderm
The present invention relates to compositions and methods for generating populations of tissue precursor cells from pluripotent cells, and preferably induction of stem cells into definitive endoderm to generate anterior foregut endoderm from pluripotent cells. The anterior foregut endoderm cells can then be differentiated into an alveolar epithelial type II cell.
US09938502B2 Tissue-specific extracellular matrix with or without tissue protein components for cell culture
The present invention relates to compositions and methods for mimicking an in vivo environment for culturing cells in vitro. The in vivo mimicking environment is based on the generation of a tissue-specific extracellular matrix wherein the matrix provides a substrate for which the cultured cell originated from. The tissue-specific extracellular matrix can further comprise a component of a whole tissue-specific homogenate.
US09938499B2 Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions
Methods and compositions for differentiating pluripotent stem cells into cells of endothelial and hematopoietic lineages are disclosed.
US09938498B2 Method for the induction and expansion of natural killer cells derived from peripheral blood mononuclear cells
The present invention relates to a method for inducing and expanding natural killer cells derived from peripheral blood mononuclear cells, which comprises co-culturing, as feeder cells, irradiated Jurkat cells and irradiated Epstein-Barr virus transformed lymphocyte continuous line (EBV-LCL) cells in the presence of cytokines, along with peripheral blood mononuclear cells. According to the present invention, a large quantity of natural killer cells can be induced and proliferated from a small quantity of peripheral blood mononuclear cells even without the use of high-cost equipment or various kinds of expensive cytokines, thereby making it possible to significantly improve the efficiency and efficacy of the prevention and treatment of cancer using the natural killer cells.
US09938489B2 Process for cleaning dishware
Process for cleaning dishware soiled with fatty residue, characterized in that said process is carried out at a temperature in the range of from 45 to 65° C. and using at least one formulation, comprising (A) in the range of from 1 to 50% by weight of at least one complexing agent, selected from the alkali metal salts of citric acid, aminocarboxylic acids and from sodium tripolyphosphate, (B) in the range of from 2 to 8% by weight of at least one non-ionic surfactant of general formula (I) R1—CH(OH)—CH2—O-(AO)x—R2 (I) (C) in the range of from 0.25 to less than 4% by weight of a copolymer, being obtained from copolymerizing the following comonomers (a) at least one comonomer selected from ethylenically unsaturated C3-C4-carboxylic acids and ethylenically unsaturated C4-C8-dicarboxylic acids or their respective anhydrides, (b) at least one comonomer selected from isobutene, diisobutene, C2-C28-a-olefins, and C12-C24-alkyl esters of (meth)acrylic acid, (c) optionally, at least one further comonomer selected from non-ionic comonomers, the integers being defined as follows: R1 being selected from C4-C30-alkyl, straight-chain or branched, and from C4-C30-alkenyl, straight-chain or branched, with at least one C—C double bond, R2 being selected from C1-C30-alkyl, straight-chain or branched, and from C2-C30-alkenyl, straight-chain or branched, with at least one C—C double bond, x being selected from one to 100, AO being identical or different alkylene oxides, selected from CH2—CH2—O, (CH2)3—O, (CH2)4—O, CH2CH(CH3)—O, CH(CH3)—CH2—O— and CH2CH(n-C3H7)—O. R1—CH(OH)—CH2—O-(AO)x—R2  (I)
US09938488B2 Process for recycling detergent pouches
A process for recycling a multi-compartment water-soluble pouch including a phosphate-free bleach-containing cleaning composition and an enveloping material. The pouch includes at least two compartments. A first compartment includes a solid composition and a second compartment includes a liquid composition. The process includes the steps of: a) releasing the compositions from their respective compartments by preferably cutting open the enveloping material; b) mixing the compositions; c) adding a moisture sink to the mixture; and d) optionally drying the mixture.
US09938482B2 Lubricating oil composition for internal combustion engine
A lubricating oil composition for an internal combustion engine according to the present invention contains a lubricating base oil, (A1) a basic calcium salicylate having a TBN of 200 mgKOH/g or more, (A2) a basic sodium sulfonate having a TBN of 200 mgKOH/g or more and/or a basic calcium sulfonate having a TBN of 50 mgKOH/g or less, (B) a binuclear organic molybdenum compound and/or a trinuclear organic molybdenum compound, and (C) a polyalkyl (meth)acrylate having an SSI of 30 or less, a total content of molybdenum derived from the binuclear and trinuclear organic molybdenum compounds being 0.025 mass % or more relative to the whole amount of the composition and the lubricating oil composition having predetermined values of a high-temperature high-shear viscosity and a NOACK value (250° C., 1 hr).
US09938473B2 Ethylene oligomerization process for making hydrocarbon liquids
Provided herein are processes for ethylene oligomerization in the presence of an ionic liquid catalyst and a co-catalyst to produce a hydrocarbon product comprising C10-C55 oligomers.
US09938471B2 Process for refining used lubricating oil
A process for taking non-treated re-refined vacuum gas oil and pretreating the product before the product is hydrotreated and used for fuel oil blends.
US09938470B2 Multi-component scavenging systems
A multi-component scavenging system containing at least one ester and at least one electron-deficient organic compound, together with or without one or more optional components such as an aldehyde having from 4 to 20 carbon atoms, a ketone having from 4 to 20 carbon atoms, an ether, a solvent, an alkali metal salt of an alkyl or dialkyl phenol, an epoxide, an alkyl anhydride, and mixtures thereof, may be used to scavenge contaminants from hydrocarbon and/or aqueous streams. The contaminants scavenged or otherwise removed may include, but are not necessarily limited to, ammonia, primary amines, secondary or tertiary amines, H2S, mercaptans, sulfide cyanides, and combinations thereof.
US09938461B2 Process for soil conditioning by aerial application of water soluble or swellable polymers
Process for soil conditioning includes applying to the soil a composition comprising at least a water soluble or swellable polymer. The composition has a particulate form and is applied by an aerial application. The process is suitable for soil conditioning and for reduction in soil erosion in agriculture, forestry, construction and civil engineering, mining, water storage and transportation, protection of rivers and delta against pollution, environmental conservation.
US09938460B2 Phosphor, light emitting apparatus and method of forming phosphor
A phosphor having a formula of TxEySizNrTbaLbMc is provided, in which T is Mg, Ca, Sr or Ba; E is Mg, Ca, Ba, Ti, Cu, Zn, B, Al, In, Sn, Sb, Bi, Ga, Y, La or Lu; L is Li, Na or K; M is Ce, Pr, Nd, Pm, Sm, Gd, Dy, Ho, Er, Tm, Yb or Mn; and 1.4≤x≤2.6, 0≤y≤0.5, 4.3≤z≤5.6, 7.4≤r≤9, 0.01≤a≤0.5, 0≤b≤0.5, 0≤c≤0.5, in which Tb ion is used as a luminescence center, and valence of the Tb ion is lower than 3+, and the phosphor is excited by an excitation light and has an emission band with a full width at half maximum greater than 50 nm. A method of forming the phosphor is also provided.
US09938459B2 Alkaline earth metal silicate phosphor and method for producing same
An object of the present invention is to provide: an alkaline earth metal silicate phosphor to which Eu is added as an activator, and which has an emission peak wavelength of 600 nm or more, high luminance and excellent color rendering properties; and a method for producing the alkaline earth metal silicate phosphor. An alkaline earth metal silicate phosphor of the present invention is represented by composition formula (1) and having an emission peak wavelength of 600 nm or more and a circularity of 85% or more. Composition formula (1): (SraCabBacEud)2SieOf (in the formula, a, b, c, d, e and f satisfy 0.4
US09938457B1 Methods for fabricating devices containing red line emitting phosphors
Methods for fabricating coated semiconductor elements are presented. The methods include the steps of combining a phosphor of formula I and a polymer binder to form a composite material, providing a semiconductor wafer including IniGajAlkN, wherein 0≤i; 0≤j; 0≤k, and a sum of i, j and k is equal to 1, coating the composite material on a surface of the semiconductor wafer to form a coated semiconductor wafer, and dicing the coated semiconductor wafer using a cutting fluid apparatus to form one or more coated semiconductor elements. A cutting fluid of the cutting fluid apparatus includes a C1-C20 alcohol, a C1-C20 ketone, a C1-C20 acetate compound, acetic acid, oleic acid, carboxylic acid, a source of A, silicic acid, or a combination thereof.
US09938450B2 Methods for optimizing salinity for enhanced water flood applications
Methods for enhanced oil recovery from subterranean formations by treating a produced water prior to injection into the subterranean hydrocarbon reservoir and manipulating produced water compositions to increase the rate and/or amount of oil that is recovered from producing wells and/or a hydrocarbon reservoir. The treatment of the produced water can increase the pH of the water from about 0.75 to about 2.0.
US09938443B2 Magnesium oxide material,thermally conductive filler and thermally conductive resin composition containing the same, and method of producing magnesium oxide material
A magnesium oxide material includes a magnesium oxide powder treated with a halogen compound and a silane coupling agent. A method of producing a magnesium oxide material includes a step including preparing a magnesium oxide powder, a halogen compound treatment step including subjecting the magnesium oxide powder to a surface treatment with a halogen compound, and a silane coupling agent treatment step including subjecting the magnesium oxide powder to a surface treatment with a silane coupling agent.
US09938442B2 Hydrofluorocarbon/trifluoroiodomethane/ hydrocarbons refrigerant compositions
A composition comprising from about 40 weight percent to about 99.9 weight percent of at least one C1-C5 hydrofluorocarbon, from about 0.1 weight percent to about 50 weight percent of CF3I, and from about 0.1 weight percent to about 10 weight percent of at least one C1-C6 hydrocarbon and the use of these composition for in methods of the recharging of refrigeration systems.
US09938437B2 Diene/dienophile couples and thermosetting resin compositions having reworkability
Thermosetting resin compositions are provided that are useful for mounting onto a circuit board semiconductor devices, such as chip size or chip scale packages (“CSPs”), ball grid arrays (“BGAs”), land grid arrays (“LGAs”) and the like (collectively, “subcomponents”), or semiconductor chips. Reaction products of the compositions are controllably reworkable when subjected to appropriate conditions.
US09938436B2 UV resistant epoxy structural adhesive
The present disclosure relates to UV resistant multi-component structural adhesive systems that are substantially free of aromatic epoxy resins, Also provided are methods of preparing the multi-component structural adhesive systems and methods of bonding substrates together with such adhesive systems.
US09938431B2 Use of non-fluorinated or partially fluorinated urethanes in coatings
The present invention is a method for imparting surface effects to a substrate using at least one hydrophobic compound with at least one linkage of Formula I: —NHC(O)—X—  (I) wherein X is the residue of a cyclic or acyclic sugar alcohol which is substituted with at least one —R1; —C(O)R1; —(CH2CH2O)n(CH(CH3)CH2O)mR2; —(CH2CH2O)n(CH(CH3)CH2O)mC(O)R1; or mixtures thereof; where the cyclic or acyclic sugar alcohol is selected from a saccharide, reduced sugar, aminosaccharide, aldonic acid, or aldonic acid lactone; wherein each n is independently 0 to 20; each m is independently 0 to 20; m+n is greater than 0; each R1 is independently a linear or branched alkyl group having 5 to 29 carbons optionally comprising at least 1 unsaturated bond; and each R2 is independently —H, a linear or branched alkyl group having 6 to 30 carbons optionally comprising at least 1 unsaturated bond, or mixtures thereof.
US09938430B2 Polyester polymer having phenolic functionality and coating compositions formed therefrom
A polyester polymer is provided that includes at least one pendant phenolic-containing group. In one embodiment, the polyester polymer is combined with an optional crosslinker and an optional carrier to form a coating composition suitable for use in coating articles such as packaging articles. The coating composition typically includes a resole phenolic crosslinker. In one embodiment, the polyester polymer has at least one phenolic-containing group that comprises an adduct of cardanol.
US09938429B2 Coatings with flexible hyperbranched polyols
A coating composition includes a flexible hyperbranched polyol preparable by (a) reacting a polyol comprising at least three hydroxyl groups with an aliphatic dicarboxylic acid having from 6 to 36 carbon atoms or an esterifiable derivative of the aliphatic dicarboxylic acid to form a hydroxyl-functional first intermediate product; (b) reacting the first intermediate product with a cyclic carboxylic acid anhydride to form a carboxylic acid-functional second intermediate product; and (c) reacting the second intermediate product with an epoxide-functional compound having one epoxide group to form the hyperbranched polyol. The coating composition may be cured to a coating layer having excellent flexibility.
US09938424B2 Coating compositions for improved block resistance
The aqueous, substantially volatile organic compound (VOC)-free coating compositions of the invention include an acrylic latex and a vinyl acetate-ethylene latex including from about 10 to about 90 weight percent of a vinyl acetate-ethylene polymer, based on total weight of acrylic polymer and vinyl acetate-ethylene polymer, having a Tg from about −20 to about 20 degrees Celsius; and from about 10 to about 90 weight percent of an acrylic polymer, based on the total weight of acrylic polymer and vinyl acetate-ethylene polymer, the acrylic polymer comprising, in polymerized form, at least one ethylenically unsaturated (meth)acrylic monomer and from about 0.01 to about 10 weight percent, based on total weight of the acrylic polymer, of an acetoacetate moiety containing monomer, where the acrylic polymer has a Tg of from about −20 to about 20 degrees Celsius.
US09938421B2 Set of ink and print medium, inkjet printing method, inkjet printing apparatus, printed matter, ink, and ink stored container
Provided is a set of an ink and a print medium, the set including an ink and a print medium, wherein the ink includes at least one organic solvent, polyurethane resin particles, a colorant, and water, wherein the at least one organic solvent includes a compound having a saturated vapor pressure at 100° C. of 65 mmHg or greater but 400 mmHg or less, and wherein a sensor output at a critical image peeling point, measured by a microscratching method, of a solid image formed on the print medium in a manner that the ink is attached in an amount of 0.96 mg/cm2 is 600 or greater.
US09938420B2 Digital fabrication of metallic articles
A method of manufacturing metallic articles from a metal substrate includes the steps of: a) jetting an image with a UV curable inkjet ink on at least one surface of the metallic substrate; b) UV curing the image; c) electroplating or acidic etching the at least one metallic surface not covered by the UV cured image; and d) stripping or solubilizing the UV cured image by an aqueous alkaline solution; wherein the UV curable inkjet ink has a viscosity of no more than 100 mPa·s at 25° C. and at a shear rate of 1,000 s−1; and wherein the UV curable inkjet ink contains a specific polymerizable composition and up to 20 wt % of photoinitiator including at least one of an acyl phosphine oxide photoinitiator and a thioxanthone photoinitiator.
US09938418B2 Surface modification of silica in an aqueous environment comprising aluminum chloride hydrate
The present invention is generally directed to treated silica particulates for use in ink-jet media coatings, comprising silica particulates being surface-activated by a surface activating agent; the surface active agent including an aluminum chloride hydrate, and where the silica particulates are also reagent-modified by an organosilane reagent; the organosilane reagent including an amine-containing silane.
US09938416B2 Absorptive pigments comprising graphenic carbon particles
Thermally produced graphenic carbon particles for use as absorptive pigments are disclosed. The pigments may be used in coatings and bulk articles to provide favorable absorbance characteristics at various wavelengths including visible and infrared regions.
US09938412B2 Bis-azo colorants for use as bluing agents
This invention relates to bis-azo colorants for use as bluing agents, laundry care compositions comprising bis-azo colorants that may serve as bluing agents, processes for making such bluing agents and laundry care compositions and methods of using the same. The bluing agents are generally comprised of at least two components: at least one chromophore component and at least one polymeric component. These bluing agents are advantageous in providing a whitening effect to fabrics, while not building up over time and causing undesirable blue discoloration to the treated fabrics.
US09938407B2 Polyarylene sulfide resin composition
A polyarylene sulfide resin composition includes: (A) a polyarylene sulfide resin having a carboxyl group content of more than 100 μmol/g and less than 400 μmol/g, and also having a weight average molecular weight of 10,000 or more and less than 100,000; and (B) a filler. The polyarylene sulfide resin composition has improved mechanical properties and chemical resistance while maintaining intrinsic high melting point of a polyarylene sulfide.
US09938405B2 Hybridized insulating resin material for high voltage equipment and high voltage equipment using the same
An object of the present invention is to provide a hybridized insulating resin material, in which a viscosity is low to ensure a molding ability and the occurrence of voids is suppressed with respect to a resin material to which 2 to 20 wt % of fine particles of 100 nm or less are added, and a high voltage equipment including the hybridized insulating resin material. The object is achieved by providing a hybridized insulating resin material for a high 1.0 voltage equipment, which contains 2 to 20 wt % of fine particles having a particle size of 100 nm or less and contains a nonion surfactant having an HLB value of 2 to 8, and a high voltage equipment including the hybridized insulating resin material.
US09938402B2 Additive composition and compositions and articles containing the same
An additive composition that includes fluoropolymer, synergist, and fatty acid metal salt.
US09938400B2 Propylene copolymers in soft thermoplastic blends
Thermoplastic polyolefins (TPOs) and/or thermoplastic vulcanizates (TPVs) are blended with low molecular weight propylene-dominated copolymers to provide polymeric compositions with an improved balance between processability and toughness. The compositions have improved processability by facilitating the ease with which a TPO or TPV, usually difficult to melt process, can be processed at high line speeds, which in turn improves the formation of the composition into articles.
US09938396B2 Nanocomposite materials with dynamically adjusting refractive index and methods of making the same
A concept and synthesis technology for a composite nanoparticle material which can be used to develop nanocomposite films and suspension with 1) dynamic refractive index control across a wide temperature and wavelength of light, and specified refractive index range, or 2) magnetic susceptibility or electronic conductivity over a wide temperature, magnetic field and electric field range. Core-shell nanoparticles can be made from two or more materials whose temperature dependent, electric field dependent or magnetic field dependent properties compensate one another will dynamically maintain a targeted refractive index, electronic conductivity or magnetic susceptibility over a specified temperature, electric and/or magnetic field range. Mixtures of composite nanoparticles with complementary behavior can optionally be used to widen the operational range of the nanocomposite material further or dampen temperature dependency in a controlled manner, e.g. using a non-random distribution of particles to affect a compensating gradient in the property of interest.
US09938390B2 Method for the preparation of macroporous particles and macroporous microclusters
A method for producing macro porous micro-clusters is proposed comprising at least the following individual steps in given order: a) synthesis of dispersed cross-linked polymeric latex primary particles starting from at least one monomer or oligomer using emulsion polymerization; b) swelling of the primary particles with a liquid comprising at least an additional charge of monomer and/or oligomer and a cross-linker, optionally further comprising functionalization agents; c) destabilization by increase of ionic strength (by adding a salt and/or acid and/or base) in a combination with application of shear, both being above the gel formation boundary of the phase diagram, until agglomerates composed of primary particles of the desired size are formed; d) polymerization of the agglomerates to form the macro porous micro-clusters. Furthermore the invention to relates to correspondingly produced micro-clusters and uses of such micro-clusters in particular for chromatographic purposes.
US09938384B2 Ultra-thin polymer film, and porous ultra-thin polymer film
The objective of the present invention is to provide a porous ultra-thin polymer film, and a method for producing said porous ultra-thin polymer film. The present invention provides a porous ultra-thin polymer film with a film thickness of 10 nm-1000 nm. In addition, the present invention provides a method for producing a porous ultra-thin polymer film, comprising the steps of: dissolving two types of mutually-immiscible polymers in a first solvent in an arbitrary proportion to obtain a solution; applying the solution onto a substrate and then removing the first solvent from the solution applied onto the substrate to obtain a phase-separated ultra-thin polymer film that has been phase-separated into a sea-island structure; and immersing the ultra-thin polymer film in a second solvent which is a good solvent for the polymer of the island parts but a poor solvent for a polymer other than the island parts to remove the island parts, thereby obtaining a porous ultra-thin polymer film.
US09938382B2 Method for producing pseudopolyrotaxane
The present invention aims to provide an industrially advantageous method of producing a powdery pseudopolyrotaxane with a high inclusion ratio. The present invention relates to a method for producing a pseudopolyrotaxane, including: an inclusion step of mixing a polyethylene glycol and a cyclodextrin in an aqueous medium to form an aqueous dispersion of pseudopolyrotaxane that contains pseudopolyrotaxane particles in which the polyethylene glycol is included in the cavities of the cyclodextrin molecules in a skewered manner; and a drying step of drying the aqueous dispersion of pseudopolyrotaxane produced in the inclusion step to obtain the pseudopolyrotaxane. In the drying step, the aqueous dispersion of pseudopolyrotaxane is sprayed and dried in a heated gas-stream.
US09938377B2 Polyamide, preparation process therefor and uses thereof
The present disclosure relates to a novel polyamide synthesized from biobased monomers. The novel polyamide comprises the repeating unit of formula I, described herein, in which R represents a covalent bond or a divalent hydrocarbon-based group chosen from saturated or unsaturated aliphatics, saturated or unsaturated cycloaliphatics, aromatics, arylaliphatics and alkylaromatics. The present disclosure also relates to a process for preparing the said polyamide, to its uses, and to articles and compositions comprising the said polyamide.
US09938369B2 Use of succinonitrile in the production of polyisocyanates comprising iminooxadiazinedione groups
The present invention relates to a method for producing polyisocyanates comprising iminooxadiazinedione groups, wherein at least one monomeric di- and/or tri-isocyanate is oligomerized in the presence of at least one catalyst and succinonitrile. The invention relates further to a reaction system for producing polyisocyanates comprising iminooxadiazinedione groups, and to the use of succinonitrile in the production of polyisocyanates comprising iminooxadiazinedione groups by catalyzed modification of monomeric di- and/or tri-isocyanates.
US09938367B2 Polymer particles
Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.
US09938366B2 Acrylic copolymer composition prepared from vinyl ester or amide functional monomers
The present invention is directed to an acrylic copolymer composition prepared from a monomer composition. The monomer composition is essentially free of solvents having a boiling point less than 120° C. and essentially free of acid functional monomers. The monomer composition or acrylic copolymer composition comprises: (A) 30 to 70 percent by weight of a monomer having the structure (I): wherein (i) X is NR′ or O, R′ is hydrogen or is a linear or branched alkyl group having 1 to 18 carbon atoms, and R is a linear or branched alkyl group having 1 to 18 carbon atoms, or (ii) X is N or O and R is a linear or branched alkyl group bonded to X to form a 5- to 7-member ring; based on the total weight of monomers in the monomer composition; and (B) 30 to 70 percent by weight of at least one different ethylenically unsaturated monomer. The present invention is also directed to curable film-forming compositions containing these acrylic copolymer compositions, and substrates coated with the curable film-forming compositions.
US09938364B2 Substituted metallocene catalysts
This invention relates to novel bridged a hafnium transition metal metallocene catalyst compounds having two indenyl ligands substituted at the 4 position, preferably 4 and 7 positions, with a C1 to C10 alkyl, where the 2 and 3 positions are hydrogen (assuming the bridge position is counted as the one position) and the bridging atom is carbon or silicon which is incorporated into a cyclic group comprising 3, 4, 5, or 6 silicon and/or carbon atoms that make up the cyclic ring.
US09938363B2 Method for obtaining and isolating polychloroprene solids
The invention relates to methods for isolating and obtaining polychloroprene solids, wherein an aqueous polychloroprene dispersion is brought in contact with steam containing coagulant, whereby the polychloroprene solid coagulates.
US09938362B2 Isoprene polymerization catalyst composition, method for producing synthetic polyisoprene, and synthetic polyisoprene
An isoprene polymerization catalyst composition includes: Component (a): a rare earth element compound having a rare earth element-oxygen bond or a rare earth element-sulfur bond; Component (b): an ionic compound; and Component (c): at least one compound selected from the group consisting of a compound of formula (X): YR1aR2bR3c and a compound having a repeating unit of formula (Y): (—Y(R1)O—) (where Y is a metal selected from groups 1, 2, 12 and 13 in a periodic table, R1 and R2 are C1-10 hydrocarbon groups or hydrogen atoms and R3is a C1-10 hydrocarbon group).
US09938361B2 Methods for preparing catalyst systems with increased productivity
Methods for producing catalyst systems with increased productivity are disclosed. The methods may comprise providing a catalyst composition comprising a solvent and a single-site catalyst component, heating an inert gas to a temperature in a range of from about 100° C. to about 150° C., and spray drying the catalyst composition in the presence of the inert gas to form a spray-dried catalyst system. Additionally, the methods may comprise providing a catalyst composition comprising a solvent, an activator, a filler material, a metallocene catalyst, and a Group 15-containing catalyst; heating an inert gas to a temperature in a range of from about 100° C. to about 150° C.; and spray drying the catalyst composition in the presence of the inert gas to form a spray-dried catalyst system.
US09938353B2 Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
Embodiments herein report compositions of alpha-1 antitrypsin fusion polypeptides or peptide derivatives thereof. In certain embodiments, compositions and methods relate to generating a construct of use in pharmaceutically acceptable compositions to treat a subject in need of alpha-1 antitrypsin therapy or treatment. In other embodiments, compositions and methods disclosed herein concern linking alpha-1 antitrypsin or derivative thereof to an immune fragment.
US09938349B2 Antibody which specifically binds to human CRTH2
There is provided an anti-human CRTH2 antibody which has desired activity by recognizing and binding to a specific human CRTH2; the antibody fragment; DNA which encodes the amino acid sequence of the antibody; a vector which comprises the DNA; hybridomas and antibody producing cells which produce the antibody; a method of producing the antibody; a composition which comprises the antibody or the antibody fragment; a treatment method and a diagnostic method of an allergic disease, an autoimmune disease, a disease accompanied by at least one of increase and hyperergasia of eosinophils; a disease accompanied by at least one of increase and hyperergasia of Th2 cells using the antibody or the antibody fragment; and a medicine and a diagnostic agent which comprise the antibody or the antibody fragment.
US09938346B2 Monospecific and bispecific anti-IGF-1R and anti-ErbB3 antibodies
Provided are monospecific and bispecific antibodies that are useful as anti-neoplastic agents and that bind specifically to human IGF-1R and human ErbB3. Exemplary antibodies inhibit signal transduction through either or both of IGF-1R and ErbB3. Exemplary polyvalent proteins comprise at least one anti-IGF-1R binding site and at least one anti-ErbB3 binding site. In certain embodiments the binding sites may be linked through an immunoglobulin constant region. AntiErbB3 and anti-IGF-1R antibodies (e.g., monoclonal antibodies) are also provided.
US09938342B2 Nucleic acid encoding anti-IL-17A antibodies
The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine IL-17 A. The disclosure more specifically relates to specific antibodies and proteins that are IL-17 A antagonists (inhibit the activities of IL-17 A and IL-17 AF) and are capable of inhibiting IL-17 A induced cytokine production in in vitro assays, and having an inhibitory effect in an antigen-induced arthritis model in vivo. The disclosure further relates to compositions and methods of use for the antibodies and proteins to treat pathological disorders that can be treated by inhibiting IL-17A or IL 17AF mediated activity, such as rheumatoid arthritis, psoriasis, systemic lupus erythematosus (SLE), lupus nephritis, chronic obstructive pulmonary disease, asthma or cystic fibrosis or other autoimmune and inflammatory disorders.
US09938337B2 Reimmunization and antibody design
The present invention relates to methods for harvesting of antibodies from an antibody library. The antibodies are harvested by utilizing a certain epitope that is analogous to the epitope of the antigen used for immunization but that may differ in global physical and biochemical properties allowing the production of antibodies against antigens that normally cannot be utilized as immunizing agents. The present invention furthermore relate to fields of use for harvested antigens in industry, agriculture and healthcare.
US09938336B2 Sequence based engineering and optimization of single chain antibodies
The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of single chain antibodies (scFvs), including stability, solubility, and antigen binding affinity. These methods and strategies can be used individually or in combination. The methods of the present invention also include the use of a database comprising scFv sequences from an experimentally screened scFv library of antibodies that have been selected to have superior solubility and stability. The invention also provides methods of using the properties found for these selected antibodies in a general approach for reshaping scFv antibodies to improve stability and solubility properties of a single chain antibody fragment.
US09938332B2 Modified ghrelin peptides
The present invention provides a peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof.
US09938327B2 Expression constructs and methods of genetically engineering methylotrophic yeast
Methods and materials for genetically engineering methylotrophic yeast are provided.
US09938325B2 HIV-1 antigens with discrete conformational forms in the V1/V2 domain and methods of use thereof
The present invention relates to a novel composition of HIV-1 Env proteins that contain structurally and immunologically distinct VI/V2 domains. Methods of isolating such proteins, and methods of using such proteins as immunogens, therapeutic agents, vaccines, and test compounds for use in identifying a HIV antiviral are also provided.
US09938322B2 β-hairpin peptidomimetics
Beta-hairpin peptidomimetics of the general formula (I), cyclo[P1-p2-p3-p4-p5-p6-p7-p8-p9-p10-p11-p12-T1-T2], and pharmaceutically acceptable salts thereof, with P1 to P12, T1 and T2 being elements as defined in the description and the claims, have Gram-negative antimicrobial activity to e.g. inhibit the growth or to kill microorganisms such as Klebsiella pneumoniae and/or Acinetobacter baumannii and/or Escherichia coli. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
US09938317B2 Enhanced purification of antibodies and antibody fragments by apatite chromatography
Methods are disclosed for use of apatite chromatography, particularly without reliance upon phosphate gradients, for purification or separation of at least one intact non-aggregated antibody, or at least one immunoreactive antibody fragment, from an impure preparation. Integration of such methods into multi-step procedures with other fractionation methods are additionally disclosed.
US09938315B2 Chemical compounds and use thereof for improving muscular quality
Chemical compounds and the therapeutic use thereof, in particular for improving muscular quality in mammals. More particularly, a method of improving muscular quality in sarcopenic mammals and treating and/or preventing sarcopenia using the chemical compounds and, in particular, sarcopenic obesity and the associated complications and/or pathologies thereof, such as loss of strength, muscle mass, performance and of physical and movement capacity. Also, a method of improving muscle quality in obese mammals and treating and/or preventing of obesity and associated complications and/or pathologies, advantageously type 2 diabetes and metabolic syndrome, using the chemical compounds.
US09938314B2 Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto
Described herein are 5-position modified cytosine nucleotides and nucleosides as well as phosphoramidites and triphosphates derivatives thereof. Further provided are methods of making and using the same, and compositions and uses of the modified nucleosides as part of a nucleic acid molecule (e.g., aptamer).
US09938313B2 Rectangular parallelepipedal maltitol
The invention concerns maltitol crystals, characterized in that they have a rectangular parallelepipedal shape and have a length to width dimensional ratio in the range 1.8 to 5.3, preferably 3±0.7, and a process for producing them.
US09938308B2 Coordination compounds having redox non-innocent ligands and flow batteries containing the same
Electrolyte solutions for flow batteries and other electrochemical systems can contain an active material capable of transferring more than one electron per oxidation-reduction cycle. Such active materials can include coordination compounds containing a metal center and at least one redox non-innocent ligand. Accordingly, flow batteries can include a first half-cell having a first electrolyte solution therein, where the first electrolyte solution contains a coordination compound having at least one redox non-innocent ligand coordinated to a metal center. Particular redox non-innocent ligands can include those bearing a quinone functional group, such as substituted catecholates bearing a quinone functional group. Some active materials can include compositions containing a coordination compound having at least one redox non-innocent ligand coordinated to a metal center, where the at least one redox non-innocent ligand is a substituted catecholate or a salt thereof bearing a quinone functional group.
US09938304B2 Catalysts with a silylene ligand
A metal complex including at least one metal atom chosen from the metals of Groups 8, 9 and 10 of the Periodic Table of the Elements and one or more ligands, wherein at least one ligand includes a cyclic silylene structure and a Lewis base which donates an electron pair to the silicon atom of the cyclic silylene structure.
US09938301B2 Dihydropyrimido fused ring derivative as HBV inhibitor
Disclosed is a dihydropyrimido fused ring derivative as a HBV inhibitor, and in particular relates to a compound shown as formula (I) or a pharmaceutically acceptable salt thereof.
US09938300B2 Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors
The disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, X1, X2, X3, n, and m are described herein.
US09938298B2 Solvated crystal form of rifaximin, production, compositions and uses thereof
The present invention describes a new crystalline form of rifaximin, characterized in that it is a solvated form of rifaximin called rifaximin τ.The invention also describes a process for the preparation of rifaximin τ, a pharmaceutical composition comprising said rifaximin form, and its use for treating inflammations and infections.
US09938295B2 N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2
The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
US09938294B2 Tricyclic heterocycles as BET protein inhibitors
The present invention relates to tricyclic heterocycles of Formula (I): which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
US09938288B1 Macrocyclic compound and uses thereof
The present invention provides novel Compound (1) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or a pharmaceutically acceptable salt thereof, optionally in a pharmaceutically acceptable carrier, and a medical uses thereof.
US09938284B2 Organic compounds
The invention relates to novel inhibitors of phosphodiesterase 1 (PDE1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cGMP/PKG mediated pathways (e.g., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e.g., congestive heart disease, atherosclerosis, myocardial infarction, and stroke.
US09938280B2 Compositions comprising folic acid derivatives, their preparations and methods of use
Described herein are methods for making folic acid derivatives, intermediates, pharmaceutical compositions and uses thereof.
US09938279B2 Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
The present invention relates to a method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) and the use of the compounds in the prevention or treatment of disease, including pre-diabetes, type 2 diabetes, syndrome X, metabolic syndrome and obesity.
US09938275B2 Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
US09938274B1 Naphthyridine compounds, medical combinations and use thereof
This invention involves the field of biomedicine, and reveals naphthyridine compounds, medical combinations and use thereof. The naphthyridine compounds has the structure as shown by Formula (I), or its stereoisomers, geometric isomers, tautomers, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or their prodrugs. The naphthyridine compounds of this invention has anti-tumor efficacy significantly superior to that of prior art. Moreover, the naphthyridine compounds of this invention can treat diseases mediated by protein kinases.
US09938272B2 Hydrazine compound as blood coagulation factor Xa inhibitor
Provided is a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X is selected from a 3-9 membered carbon ring or a ring which is formed by 3-9 membered carbocyclic ring fused with benzo ring, and a 4-10 membered heterocyclic ring or a ring which is formed by 4-10 membered heterocyclic ring fused with benzo ring; Y and Z are independently selected from 4-9 membered saturated heterocyclic rings respectively; R1-3 are independently selected from H, F, Cl, Br, I, CN, OH, SH, NH2, CHO, COOH respectively, or selected from the group, optionally substituted by R01, consisting of C1-10 alkyl, C1-10 heteroalkyl, C3-10 cyclohydrocarbyl, C3-10 heterocyclohydrocarbyl, C1-10 alkyl substituted by C3-10 cyclohydrocarbyl or C3-10 heterocyclohydrocarbyl, and C1-10 heteroalkyl substituted by C3-10 cyclohydrocarbyl or C3-10 heterocyclohydrocarbyl. The compound can be used as an anticoagulant for treating and preventing thrombotic disorders, and can meet the real needs of selectivity and a potent inhibitor for coagulation Xa.
US09938271B2 Inhibitors of human immunodeficiency virus replication
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
US09938270B2 Mono-phosphate salt of 6-fluoro-2-[4-(pyridin-2-yl)but-3-yn-1-yl]imidazo[1,2A]pyridine (dipraglurant) and polymorphs thereof as negative allosteric modulator of MGLU5 receptor
The present invention relates to crystalline and amorphous forms of 6-fluoro-2-[4-(pyridin-2-yl)but-3-yn-1-yl]imidazo[1,2-a]pyridine mono-phosphate salt and methods of making these solid forms thereof. The invention compounds are modulators of mGlu5 which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGlu5 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGlu5 is involved.
US09938269B2 Inhibitor compounds of phosphodiesterase type 10A
The present invention relates to novel carboxamide compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating or controlling medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
US09938268B2 C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof
Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.
US09938266B2 Selective BACE1 inhibitors
The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof.
US09938262B2 Benzamides
Novel benzamide derivatives of formula (I) wherein W1, W2, R1 to R7, R6, X and Y have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.
US09938259B2 Therapeutic compositions and related methods of use
Compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
US09938257B2 Substituted heteroaryl compounds and methods of use
The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.
US09938255B2 Metalloenzyme inhibitor compounds
The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
US09938252B2 Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, are provided herein. Also provided are pharmaceutical compositions comprising at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described; which comprise administering to such patients an amount of at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein as a single active agent or administering at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
US09938251B2 Cyclic ketone peroxide composition
A composition comprising at least two trimeric cyclic ketone peroxides: a trimeric cyclic methyl ethyl ketone peroxide (3MEK-cp) of formula (I) and at least one peroxide satisfying formula (II) wherein R1 through R3 are independently selected from alkyl and alkoxyalkyl groups, said groups having 2 to 5 carbon atoms, the total number of carbon plus oxygen atoms of R1−R2+R3 is in the range 7-15, and the molar ratio of 3MEK-cp to the total amount of peroxides satisfying formula (II) being in the range of from 10:90 to 80:20.
US09938250B2 Antifibrotic effects of oxetanyl sulfoxides
A compound, or a pharmaceutically acceptable salt thereof, having a structure of wherein Z is aryl or substituted aryl, heteroaryl, or substituted heteroaryl; X is —S—, —S(O)—, or S(O)2—; R20 and R21 are each independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, or halogenated alkyl; one of R22, R23, and R24 is —O— and the others of R22, R23 and R24 are independently —CH2—, or —C(R13)— wherein R13 is alkyl, alkenyl, alkynyl, trialkylsilyl group, or —(CH2)mOR15, wherein R15 is alkyl or an aryl and m is an integer in the range of 1 to 10; and R25 is H, alkyl, substituted alkyl, halogen, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, C1-C3 alkoxy, aryloxy, or —(CH2)qOR17, wherein R17 is alkyl an aryl and q is an integer in the range of 1 to 10.
US09938243B2 Compounds for affinity chromatography and for extending the half-life of a therapeutic agent
Compounds useful for affinity chromatography as presented, more particularly for use in affinity chromatography to purify serum albumin, especially human serum albumin (HSA) and fusion proteins thereof. Methods for extending the half-life of therapeutic agents are also presented, particularly therapeutic peptide agents and small molecules, such as by conjugation of compounds described herein to the therapeutic peptide or small molecule, which, upon administration, binds to HSA, thereby providing a prolonged release of the therapeutic agent.
US09938236B2 Antiviral agents against HBV infection
The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.
US09938233B2 Purification of X-ray contrast agents
The present invention relates to a process for purification of iodinated X-ray contrast agents and in particular to purification of crude dimeric contrast agents, such as Iodixanol and Ioforminol. More particularly, the invention relates to purification of such X-ray contrast agents using membrane technology to remove monomeric impurities.
US09938226B2 Gas phase production of alkyl alkanoate
Alkyl alkanoates, e.g., methyl propionate, are made by a gas phase process comprising the step of contacting under carbonylation conditions an alkene (e.g., ethylene), carbon monoxide, an alkanol (e.g., methanol), and a solid sulfide-based metal catalyst (e.g., iron sulfide). The alkyl alkanoate can be converted in a second step to an alkyl ester of an aliphatic carboxylic acid, e.g., methyl methacrylate, through condensation with an aldehyde, e.g., formaldehyde.
US09938224B2 Methods for producing alkyl hydroxyalkanoates
Methods and systems for producing alkyl hydroxyalkanoate from hydroxy carboxylic acid recovery bottoms. The methods generally comprise the steps of obtaining a hydroxy carboxylic acid recovery bottom, adding a mono-alcohol to the hydroxy carboxylic acid recovery bottom to obtain a first mixture, beating the first mixture in the presence of a catalyst to form a reaction product, distilling the reaction product, and recovering an alkyl hydroxyalkanoate fraction.
US09938223B2 Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
Disclosed are methods for the catalytic transesterification of compounds having one or more ester groups and groups reactive under transesterification conditions, such as 1,1-disubstituted alkene compounds, with alcohols or esters and novel compositions prepared therefrom. Further disclosed are novel compounds and compositions prepared as a result of the methods.
US09938222B2 Cyclopropanecarboxylic acid GPR120 modulators
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
US09938219B2 Process and system for making cyclohexanone
Disclosed are processes and systems for making cyclohexanone from a mixture comprising phenol, cyclohexanone, and cyclohexylbenzene, comprising a step of or a device for subjecting at least a portion of the mixture to hydrogenation and a step of or a device for distilling a phenol/cyclohexanone/cyclohexylbenzene mixture to obtain an effluent rich in cyclohexanone.
US09938216B2 Methanol purification method and apparatus
The invention relates to a method and apparatus to recover and purify methanol from gases produced in the digester during the kraft pulping process. The gas is typically recovered as a foul gas (called stripper off gas or SOG) comprising methanol, water and various other contaminants. The gas is then treated with successive decanting and distillation steps to remove impurities, thereby producing highly purified methanol.
US09938208B2 Catalytic chlorination of 3,3,3-trifluoropropene to 2,3-dichloro-1,1,1-trifluoropropane
The present invention relates to a process for preparing 1,1,1-trifluoro-2,3-dichloropropane which comprises contacting chlorine with 3,3,3-trifluoropropene in the presence of a catalyst to form 1,1,1-trifluoro-2,3-dichloropropane, wherein the catalyst comprises at least one metal halide, where the metal is a metal from Group 13, 14 or 15 of the periodic table or a transition metal or combination thereof.
US09938207B2 Upgrading paraffins to distillates and lube basestocks
A process for converting paraffins, especially light paraffins, e.g. C3-C8 paraffins, to higher boiling range paraffinic liquid hydrocarbons comprises endothermically dehydrogenating the light paraffin combined with a thermally coupled, exothermic reaction such as olefin oligomerization to supply heat for the endothermic conversion.
US09938203B2 Pyrotechnic compositions comprising nanostructured crystalline boron phosphide and oxidizer
A novel pyrotechnic composition comprising nanostructured crystalline boron phosphide and oxidizer such as potassium nitrate wherein the crystalline boron phosphide is synthesized by a self-propagating high-temperature reaction. The nanostructured crystalline boron phosphide and oxidizer pyrotechnic composition unexpectedly emits smoke and green flame upon ignition.
US09938197B2 Unleaded piezoelectric ceramic composition, piezoelectric element using same, device, and method for manufacturing unleaded piezoelectric ceramic composition
A lead-free piezoelectric ceramic composition includes a first crystal phase made of an alkali niobate/tantalate type perovskite oxide having piezoelectric properties, and a second crystal phase made of an M-Ti—O spinel compound (where the element M is a monovalent to quadrivalent element).
US09938191B2 Establishing control of oil and gas producing wellbore through application of self-degrading particulates
Remediation of a hydrocarbon producing well bore in a subterranean formation includes injecting fluid containing self-degrading particulates into the well bore in order to stop production of hydrocarbon from the well bore prior to commencement of remedial operations and to temporarily seal the well bore from fluid transmission between the well bore and the formation prior to commencement of the remedial operations, and commencing the remedial operations upon the well bore. Examples of the remedial operations include injecting weighted fluid into the well bore, inserting a down-hole tool into the well bore, casing treatment, annulus treatment, well bore wall treatment, cementing, and refracturing. For refracturing, the fluid containing the self-degrading particulates can be injected until a down-hole pressure exceeds a fracture breakdown pressure of new fractures that will be produced by a perforating tool lowered into the well bore.
US09938189B2 Pervious composite materials, methods of production and uses thereof
The invention provides novel pervious composite materials that possess excellent physical and performance characteristics of conventional pervious concretes, and methods of production and uses thereof. These composite materials can be readily produced from widely available, low cost raw materials by a process suitable for large-scale production with improved energy consumption, desirable carbon footprint and minimal environmental impact.
US09938187B2 Method and apparatus for material processing using multiple filamentation of burst ultrafast laser pulses
A method of drilling multiple orifices in and texturing a substrate is disclosed and includes the following steps. Ultrafast laser pulses are passed through a beam splitting diffractive optical element and then multiple beams are passed through a distributive-focus lens focusing assembly. The relative distance and/or angle of said distributive-focus lens focusing assembly in relation to the laser source is adjusted focusing the pulses in a distributed focus configuration creating a principal focal waist and at least one secondary focal waist. The fluence level of the at least one secondary focal waists is adjusted such that it is or they are of sufficient intensity and number to ensure propagation of multiple filaments in the substrate. Photoacoustic compressive machining is performed and forms multiple volume(s) within the substrate.
US09938184B2 Sizing composition for fibers, in particular mineral fibers, comprising a non-reducing sugar and an inorganic acid ammonium salt, and resulting products
A formaldehyde-free sizing composition for products based on fibers, in particular mineral fibers, such as fibers of glass or of rock, includes at least one non-reducing sugar, and at least one inorganic acid ammonium salt, preferably chosen from ammonium sulfates, phosphates, nitrates and carbonates. Another subject matter of the present invention is the products thus obtained, in particular thermal and/or acoustic insulators based on mineral wool and veils of nonwoven mineral fibers, and their process of manufacture.
US09938183B2 Sealing glass paste
A sealing glass paste for reducing the laser energy required during a sealing process. The sealing glass paste comprises a light absorbing material.
US09938180B2 Methods of cutting glass using a laser
A method of cutting a glass article includes translating a laser beam relative to a first surface of the glass article. The laser beam includes a beam waist having a center. The center of the beam waist of the laser beam is positioned at or below a second surface of the glass article. The laser beam creates a plurality of defects along a score line in the glass article such that the plurality of defects extends a distance into the glass article, and at least some individual defects of the plurality of defects are non-orthogonal to the first surface of the glass article and are biased in a direction of translation of the laser beam. Glass articles having edge defects are also disclosed.
US09938179B2 Method and system for forming shaped glass articles
A method of forming a shaped glass article includes placing a glass sheet on a mold such that a first glass area of the glass sheet corresponds to a first mold surface area of the mold and a second glass area of the glass sheet corresponds to a second mold surface area of the mold. The first glass area and the second glass area are heated such that the viscosity of the second glass area is 8 poise or more lower than the viscosity of the first glass area. A force is applied to the glass sheet to conform the glass sheet to the mold surface. During the heating of the second glass area, the first mold surface area is locally cooled to induce a thermal gradient on the mold.
US09938176B1 Chloroperoxidase-catalyzed degradation of pharmaceutical pollutants in wastewater
The present invention provides efficient, economical, and environmentally-friendly compositions and methods for removing pollutants from water sources. In particular embodiments, the present invention provides compositions and methods for catalyzing the degradation of pharmaceutical pollutants in wastewater using the enzyme chloroperoxidase (CPO). Another embodiment provides a method of degrading pollutants in wastewater and other water sources. In specific embodiments, the claimed composition and method can be used to degrade pharmaceutical pollutants selected from the group consisting of: acetaminophen, carbamazepine, sulfamethazine, diclofenac, and naproxen.
US09938175B2 Bio-assisted process for the treatment and regeneration of spent caustic
The present invention relates to a bio-assisted method for treatment of spent caustic by treating with haloalkaliphilic consortium of bacteria capable of reducing or transforming sulphides, thiols, mercaptants and other sulphur containing compounds, phenols, hydrocarbons, naphthenic acids and their derivatives in spent caustic.
US09938174B2 Algae turf plate scrubber
An apparatus and method for the biological treatment of water using algae comprising a support frame for flat, two-sided LED lighting-panels and flat, two-sided algae turf plates, an axle, the flat, two-sided LED lighting panels and flat algae turf plates are arranged as spokes radiating from the axle in an alternating panel so that each side of each two-sided lighting panel faces and illuminates a side of a flat algae turf plate, the algae turf plates being removable from the support frame so that the collected algae can be removed from each side of each the algae turf plate.
US09938170B2 Synthetic acid and associated methods
Glycine is an organic compound that can be used in the making of a synthetic acid that obviates all the drawbacks of strong acids such as hydrochloric acid. The new compound is made by dissolving glycine in water, in a weight ratio of approximately 1:1 to 1:1.5. The solution is mixed until the glycine is essentially fully dissolved in the water Once dissolution is complete, hydrogen chloride gas is dissolved in the solution to produce the new compound, which can be referred to as hydrogen glycine. Also disclosed is a method for adjusting the pH of a fluid, the method comprising adding an effective amount of a solution to the fluid for adjusting the pH thereof to a desired level wherein the solution is prepared by mixing glycine in water to form a glycine solution; and adding hydrogen chloride to the glycine solution.
US09938164B2 Hydrocarbon-water separator
An apparatus for separating hydrocarbons from water, comprising a tank segment with a fluid inlet subsequent a housing with a liquid-gas mixer. The fluid inlet through a cylindrical tank wall, and further through the wall of a conical wall segment, a pipe spread, combining radial and axial flow over ring mounted guide vanes at the upper part of the conical wall segment. A hydro carbon outlet is located at a top end and a water outlet at a bottom end of tank-segment. A pipe for scale and debris removal is connected to the lower part of the bowl. The inner conical wall segment extends to the top end of the tank segment and at this location comprises a ring of vertically mounted guide vanes.
US09938154B2 Precipitated silica production process
A precipitated silica production process that includes a precipitation reaction between a silicate and an acid is described, in which the acid used in at least one of the steps of the process is a concentrated acid.
US09938152B2 Method of making activated nano-porous carbon
An activated nano-porous carbon is produced using a liquid organic compound as a starting material. A combination of the liquid organic compound with organic acids is mixed with conductive carbon powder and polymerized. The polymerized material is then carbonized and activated using physical or chemical methods. The activated nano-porous carbon obtained using this method has been used to fabricate EDLC devices. The carbon has also shown large surface area (up to ˜2000 m2/gm, depending on the degree of activation) and can be used for various other activated carbon applications.
US09938150B2 Preparation method of graphene as well as graphene oxide based on anthracite
The present invention relates to a preparation method of graphene oxide based on anthracite. The method consists of the following steps. a. Preparation of ultra-clean anthracite powder; b. Pretreatment of ultra-clean anthracite powder; c. Preparation of anthracite oxide dispersion; d. Preparation of graphene oxide colloid solution; e. Preparation of graphene oxide. The invention also relates to a preparation method of graphene using graphene oxide obtained by method mentioned before. The method consists of the following steps. f. Preparation of graphene oxide-dispersant solution; g. Reduction of graphene oxide; h. Obtaining graphene by suction filtration and drying process. Based on the preparation of anthracite, the invention could reduce production costs effectively comparing to traditional preparation methods of graphene and graphene oxide, and make the reaction more fast and complete, facilitating the achievement of large scale industrial production.
US09938146B2 High aspect ratio catalytic reactor and catalyst inserts therefor
The present invention relates to high efficient tubular catalytic steam reforming reactor configured from about 0.2 inch to about 2 inch inside diameter high temperature metal alloy tube or pipe and loaded with a plurality of rolled catalyst inserts comprising metallic monoliths. The catalyst insert substrate is formed from a single metal foil without a central supporting structure in the form of a spiral monolith. The single metal foil is treated to have 3-dimensional surface features that provide mechanical support and establish open gas channels between each of the rolled layers. This unique geometry accelerates gas mixing and heat transfer and provides a high catalytic active surface area. The small diameter, high aspect ratio tubular catalytic steam reforming reactors loaded with rolled catalyst inserts can be arranged in a multi-pass non-vertical parallel configuration thermally coupled with a heat source to carry out steam reforming of hydrocarbon-containing feeds. The rolled catalyst inserts are self-supported on the reactor wall and enable efficient heat transfer from the reactor wall to the reactor interior, and lower pressure drop than known particulate catalysts. The heat source can be oxygen transport membrane reactors.
US09938145B2 Method and system for adjusting synthesis gas module in an oxygen transport membrane based reforming system
A method and system for producing a synthesis gas in an oxygen transport membrane based reforming system is disclosed that carries out an air heated pre-reforming process, a primary reforming process, a secondary reforming process.
US09938142B2 Hydrogen storage material and manufacturing method thereof
A hydrogen storage material includes Mg(NH2)2, LiH, and MgH2. A manufacturing method of a hydrogen storage material includes steps of manufacturing a mixture by mixing Mg(NH2)2, LiH, and MgH2, and pulverizing the mixture.
US09938132B2 Dispensing device and group of such dispensing devices
The invention relates to a dispensing device for flowable products, the dispensing device comprising: at least a first and second plugs adapted to allow or prevent the flow of product; a first guide block comprising a guide hole adapted to guide the first plug, and a channel in communication with the guide hole, that allows the passage of maintenance fluid; a second guide block isolated from the first guide block, the second guide block comprising a guide hole able to guide the second plug, and a channel for passage of maintenance fluid, and a coupling adapted to connect in a fluidtight manner the channel of the first guide block to the channel of the second guide block, in order to allow the passage of maintenance fluid.
US09938131B2 Wine dispenser that protects unpoured wine from oxidation by preventing air from entering the dispenser when partially full
A wine dispenser is disclosed that protects unpoured wine from oxidation due to exposure to air within the dispenser. The dispenser includes a dispenser body having a weighted piston disposed within, the weighted piston being configured to move toward the dispensing end of the dispenser body when the dispenser is tilted downward, causing wine to be dispensed via a dispensing assembly. The dispensing assembly includes a lid having a wine flow channel that provides a path for wine to flow out of the dispenser body, and a unidirectional flow valve that is biased in a closed air-tight state to prevent air from entering the dispenser body via the wine flow channel, unless the unidirectional flow valve is forced into an open state, thereby allowing wine to flow out from the dispenser body via the wine flow channel, and then out of the dispenser via a pouring neck.
US09938129B2 Plastic beer keg
A plastic keg includes a liner including a neck portion and a body portion. A lid having an opening is disposed at least partially over the liner. A retainer is secured to the neck portion of the liner and aligned with the opening in the lid, the retainer including external threads. A locking ring having internal threads is secured to the external threads of the retainer. The internal threads of the locking ring and the external threads of the retainer include a ratcheting mechanism permitting attachment of the locking ring to the retainer and inhibiting removal of the locking ring from the retainer, the locking ring contacting the lid. A beer keg valve assembly includes a port having a head portion having a convex upper surface and at least one leg extending downwardly from a lower surface. The leg includes a stop surface projecting radially outward further than the head portion. A piston defines an opening. A spring biases the port against a periphery of the opening defined by the piston to seal the convex upper surface of the head portion over the opening.
US09938126B2 Lifter
A lifter is provided with operating levers, which, against driving forces of actuators that switch the ratchet pawls to unengaged orientations, switch the ratchet pawls to engaged orientations of being engaged with ratchet gears, is provided with a link mechanism, which, when a workpiece support base is being lowered by collapsing motions of a pair of right and left crosslink mechanisms supporting the workpiece support base and a difference arises in movement amounts of movable support shafts at lower end sides of the respective crosslink mechanisms, converts the movement amount difference to an operating force of the operating lever at the larger movement amount side, and is such that by the operating lever at one side being driven by the link mechanism, the operating lever switches the ratchet pawl at the larger movement amount side to the engaged orientation.
US09938125B2 Lever adapter for use with jack and lifting devices
Embodiments in the present description are provided for a lever adapter device for use in lifting a vehicle or other heavy objects. The lever adapter device includes stabilizing feet and one or more support legs. Each one of the stabilizing feet is attached to an end of each support leg. The lever adapter device further includes a hinge disposed at an end of each support leg. Each support leg is extendable and retractable towards or away from the other support leg. The lever adapter device further includes a jack attachment piece and one or more hinges, which are also connected to the one or more support legs. The jack attachment piece is configured to be removably connected to a jack, such as a HI-LIFT jack, or to other lifting devices to assist in lifting the vehicle or the other heavy objects.
US09938123B1 Valve box lifter
A gripping mechanism extends from a clamping mechanism. The clamping mechanism includes a fixed handle, a pivotally connected movable handle, a releasable locking mechanism, and the upper section of two opposing L-shaped arms. The lower section of each arm extends from the clamping mechanism to connect to a pair of lugs to form the gripping mechanism. Each lug includes an elongated member and a gripping surface for gripping a valve box cover lid. The gripping mechanism is manipulated to pivot the arms and move the gripping surfaces into place to grip the valve box cover lid. Once the gripping surfaces grip the lid, the arms are locked into a fixed position relative to one another to facilitate the separation of the cover, the lifting of the cover, and the transportation of the cover from the valve box.
US09938120B2 Transport device
The distance between a pair of fall prevention members can be adjusted by causing the pair of fall prevention members to be linearly moved in mutually opposite directions along the spaced-apart direction along which the pair of fall prevention members are spaced apart from each other. A distance adjustment actuator portion is configured to be able to adjust the distance between the pair of fall prevention members to any of a distance for retraction greater than a width of a larger transported object in the spaced-apart direction; a distance for the larger transported object which is less than the distance for retraction and which corresponds to the width of the larger transported object in the spaced-apart direction; and a distance for the smaller transported object which is less than the distance for the larger transported object and which corresponds to a width of the smaller transported object in the spaced-apart direction.
US09938119B2 Method and apparatus for retrofitting a pedestal crane
A method and apparatus are disclosed for retrofitting a pedestal crane, the method comprising removing an existing motor generator controller for a motor in the pedestal crane; and replacing the motor generator controller with a digital controller.
US09938117B2 Mobile conductor lift
A conductor lift attachment for a mobile boom or crane vehicle allowing temporarily support of power transmission conductors, e.g., for installation, repair, or maintenance operations. The conductor lift is hingedly attached to a boom tip so that the conductor lift is readily movable between deployed and stowed positions. The conductor lift comprises hinged arms that are selectively movable between opposed, parallel, and intermediate positions.
US09938116B2 Self-centering elevator cage door suspension
An elevator installation includes an elevator cage, which is movable in an elevator shaft, with a cage door suspension for a cage door, wherein the cage door suspension is movably arranged at the elevator cage by means of at least one movable mount. During operation of the elevator installation, a self-centering aligning movement of the cage door suspension from a skewed setting of the elevator cage, in correspondence with a skew setting axis, to an approximately vertical and centered setting of the cage door suspension in correspondence with a vertical, can be performed.
US09938115B2 System and method for limiting over-voltage in power supply system
A system and method for providing a protective extra low voltage power supply in an elevator system (2) is disclosed. The power supply system (10) may include a switch mode power supply (12) configured to provide an output voltage, a first voltage monitor (18) and a second voltage monitor (20). Each of the first voltage monitor (18) and the second voltage monitor (20) may be configured to receive the output voltage and determine an over-voltage condition at the switch mode power supply (12).
US09938114B2 Method and device for winding a metal strip
The invention relates to a method for winding a metal strip (1) into a reel with a winding mandrel (2), to which the metal strip (1) is routed through a pair consisting of a first and a second driver roller (5, 6), at least one of which is driven. The method is characterized in that a difference between the strip speed (VB) of the metal strip (1) and the speed) (v5, v6) of the driver rollers is adjusted on the basis of measuring, from measurable process variables, the strip speed and the speed (v5, v6) of at least one of the driver rollers (5, 6).
US09938107B2 Medium discharge device and image reading apparatus
A medium discharge device includes a discharge roller pair that is provided with a discharge driving roller and a discharge driven roller which drivably rotates in contact with the discharge driving roller, and a medium receiving tray which receives the medium that is fed and discharged by the discharge roller pair, in which the medium receiving tray includes a guide member which guides such that a tip end of the medium which is discharged from the discharge roller pair enters the medium mounting surface at a predetermined angle, and the guide member is provided to be elastically displaceable in an advancing and retreating direction with respect to the medium mounting surface of the medium receiving tray and is displaced in a direction coming close to the medium mounting surface according to raising of a pressing load due to the medium that is discharged to the medium receiving tray.
US09938104B2 Apparatus and methods for facilitating the removal of existing turf and installing new turf
A turf cutter device, an infill extractor/collector device, and a turf wind-up device are used to facilitate the cost-effective removal of an infilled synthetic turf and the subsequent installation of a new turf at the same site, with minimal subsurface disruption. An infill extractor/collector device mounted on a motorized vehicle moves a relatively narrow strip of filled artificial turf from the surface, in front of the vehicle, and directs the strip to an infill removal station. The infill removal station inverts the strip and redirects the strip back toward the front of the vehicle, after agitating the strip to extract the infill. After redirecting the strip toward the front of the vehicle, the vehicle drives over the unfilled strip. Meanwhile, the extractor/collector device moves the extracted infill rearwardly to a bag located in a trailer. The turf cutter device is used prior to infill extraction, while the turf wind up device may be used before or after infill extraction, depending on whether infill extraction takes place at the field or at a remote site, respectively.
US09938098B2 Roller drive transmission device and automatic document feeder and image forming apparatus provided with same
A roller drive transmission device includes a drive input gear, a drive transmission gear, a roller unit and a ratchet mechanism. When a rotational drive force is input to the drive input gear and the drive transmission gear is slid to a first position, the drive input gear, the drive transmission gear and the roller unit are integrally rotated in a first rotational direction. When the input of the rotational drive force to the drive input gear is cut off and the roller unit is rotated, following a sheet, the drive transmission gear is slid to a second position and the roller unit and the drive transmission gear are decoupled. The ratchet mechanism includes a load adjustment mechanism configured to make a rotational load in the first rotational direction of the drive transmission gear arranged at the second position larger than a movement load in an axial direction.
US09938096B2 Sheet supply apparatus
A sheet supply apparatus detachably attached to an image forming apparatus is configured to receive a drive force from the image apparatus to supply sheet to the image forming apparatus. The sheet supply apparatus includes a sheet supply tray, a sheet supply roller, a first transmission mechanism configured to transmit a drive force from the image forming apparatus to the sheet supply roller, a second transmission mechanism including an output member and configured to transmit a drive force supplied from the image forming apparatus to the output member, a clutch mechanism configured to intermittently transmit a drive force from the image forming apparatus to the second transmission mechanism, a latch member pivotable between a restriction position and an allowance position, a change cam, a sector gear, a rotational force applying member, an engaging member, a first engagement portion, a second engagement portion, and an electromagnetic solenoid.
US09938092B2 Perception-based robotic manipulation system and method for automated truck unloader that unloads/unpacks product from trailers and containers
An automated truck unloader (10) for unloading/unpacking product, such as boxes or cases, from trailers and containers is disclosed. In one embodiment, a mobile base structure provides a support framework for a drive subassembly, conveyance subassembly, an industrial robot (56), a distance measurement subassembly, and a control subassembly (62). Under the operation of the control subassembly, an industrial robot (56) having a suction cup-based gripper arm selectively removes boxes from the trailer and places the boxes on a powered transportation path (88). The control subassembly (62) coordinates the selective articulated movement of the industrial robot (56) and the activation of the drive subassembly based upon a perception-based robotic manipulation system.
US09938091B2 Conveying method and conveying device of rubber member
In a conveying method of a rubber member for receiving the rubber member which is supplied from a supply device and is curved, and transferring the received rubber member to a supply receiving device in a curved state, the method includes a step of winding the rubber member from a leading end portion onto a mounting surface of a rotary table by forwardly rotating the rotary table and receiving the rubber member from the supply device in a state in which a rear end portion of the rubber member is not in contact with the mounting surface, a step of moving the rotary table from a receiving position to a transferring position, and a step of winding back the rubber member from the rear end portion so as to transfer the rubber member to the supply receiving device by reversely rotating the rotary table.
US09938090B2 Container raising/lowering conveyance apparatus
A container raising/lowering conveyance apparatus has at least two lifting raising/lowering bodies corresponding respectively to two parallel side surfaces of an article-conveyance container are capable of being raised and lowered, and moved closer to and away from each other. Support units are attached to each of the lifting raising/lowering bodies and pairs of pin-shaped supporting implements in the support units protrude towards the container side at symmetrical positions at both sides of a vertical center line of each of the two parallel side surfaces of the container are arranged and supported at suitable intervals in a vertical direction. Each pin-shaped supporting implement is capable of extending and retracting, and is impelled into and held in a protruded position by a spring. Pairs of pin-shaped supporting implements having a narrow interval therebetween and pairs of pin-shaped supporting implements having a broad interval therebetween are arranged alternately in the vertical direction.
US09938088B2 Conveying device
A conveying device has interlockingly coupled, rectilinear screw shafts which are driven by a motor. The screw shafts are juxtaposed to an inclined rectilinear portion of a gradient portion in a traveling route of a conveying traveling body and to at least fixed regions adjacent to the gradient portion of respective upper and lower horizontal route portions connected to respective ends of the gradient portion. The conveying traveling body has a pair of front and rear driven rollers engaging with the screw shafts, and an interval between the pair of front and rear driven rollers is set to a length not shorter than a rectilinear distance between end portions of the screw shafts positioned at respective sides of each of arcuate portions at respective upper and lower ends of the gradient portion to make the conveying traveling body travel continuously between the respective upper and lower horizontal route portions.
US09938082B2 Pharmaceutical dispensing system and associated method
A dispensing system and associated method provides a turnkey solution for dispensing pharmaceutical products such as solid medications and nutritional supplements to be taken orally in health care settings, including but not limited to long term care (LTC) and assisted living settings.
US09938078B2 Pushing type lid opening/closing device of a container and a pushing type lid opening/closing unit
A pushing type lid 20 of a container is pivotally supported adjacent to an upper edge wall of an opening 2 of width smaller than width of a front board 1BF of a box body 1B and adapted to be manually pushed inwards so as to be opened and to be automatically closed when a hand is released from the lid 20 and there is provided a pair of hand and/or finger catch prevention wall member 50 to prevent a hand and/or fingers from being caught between the lid 20 and the wall face of the opening 2.
US09938077B2 In-ground receptacle and installation thereof
An in-ground apparatus includes a receptacle and a liner into which the receptacle can be placed and removed. The liner may be a molded plastic liner having a tapering body to permit stacking. The lower margin includes a set of seats for anchor fittings in the form of re-bar prongs that, when installed, extend radially outwardly from the liner. The seats, and hence the prongs, are located upwardly of the bottom edge of the liner so that they are embedded above and below when concrete is poured around the bottom of the liner. The bottom edge of the liner is folded upwardly and inwardly to form a V-shaped channel. The seats for the anchor fittings extend across the channel. The seats may include a cylindrical wall sealed from the inside of the liner. The liner may have intermediate stiffening ribs between bottom and top. The top of the liner may have a seat for the receptacle, and an external concrete break.
US09938076B2 Flexible storage device comprising a flexible container and an inner liner
A storage device (1) for bulk material intended for powdery materials, includes a flexible container (2) for bulk material and an insulating inner liner (3), of which the surface resistivity is greater than 1.0×1012Ω, without a static electricity conductive layer and without a static electricity dissipation layer, the inner lining (3) covering the inner walls of the container, the inner lining (3) including micro-perforations that pass there through, distributed over the whole surface of the inner lining (3) in such a way that the breakdown voltage of the inner liner (3) is lower than 4 kV and the breakdown voltage of the wall of the container is lower than 6 kV.
US09938073B2 Pipe intermodal logistics system
The proposed invention relates to a pipe intermodal logistics apparatus and system to facilitate the transportation and storage of industrial pipe The pipe intermodal logistics apparatus includes a lower clamp which embraces the weight of one or more pipes, and an upper clamp which engages the upper surfaces of the one or more pipes to be transported. The lower and upper clamps each frictionally engage with surfaces of the one or more pipes to prevent longitudinal and lateral movement of the pipes during transportation.
US09938072B2 Foam dispenser
A dispenser for producing a foam without requiring the use of liquefied gas, from an outlet. The dispenser includes a receptacle for holding a surfactant solution, means for supplying a gas, means for conveying the surfactant solution in the receptacle and said gas along a flow path towards the outlet. The conveying means includes a conduit having a foaming section for generating the foam from the surfactant solution and said gas; and wherein the foaming section has internal dimensions adapted to provide a foam having a quality characterized by predefined limits.
US09938070B2 Nozzle cap for aerosol container
Provided is a nozzle cap for aerosol container that can be used for cleaning a nozzle of an aerosol container that has a plurality of stems, and preventing the nozzle from being pushed down. The nozzle cap includes a plurality of bar-like pieces 11 that can be inserted from ejection ports 24 of a nozzle 20 into ejection-side communication passages 23a at least until distal ends 11a reach upper ends 22d of stem-like communication passages 22a, and a lower protrusion 14 that prevents the nozzle from being pushed down by abutting on a cover member 30 below ejection tubes 23 of the nozzle 20 when the bar-like pieces 11 are inserted into the ejection-side communication passages 23a.
US09938069B2 Medical device sanitizer
Some embodiments of the present disclosure include a sanitizing device for sanitizing a medical device. The sanitizing device may include a spray canister configured to accommodate a volume of a sanitizing fluid, the spray canister having at least one spray head extending therefrom, wherein the spray head is configured to expel sanitizing fluid when depressed; a body with an openable lid, the body configured to accommodate the spray canister, wherein a distance between an upper surface of the spray canister and an interior surface of the lid is sufficient to accommodate the medical device; and a lid protrusion extending downwardly from an interior surface of the lid, wherein the lid protrusion aligns with the spray head when the spray canister is positioned within the body. When the lid is closed, the lid protrusion may depress the spray head, resulting in the sanitizing fluid being expelled from the spray head.
US09938068B2 Cooler/lunch bag with detachable liner
A cooler/lunch bag has a detachable liner, which is attached to the bag by engaging a row of round studs on the bag with a row of “+” shaped slits in the liner. After the liner is detached, it can be folded up, inverted and covered by its plastic base in a storage position. Such cooler/lunch bag can be thoroughly cleaned and is suitable for long-term use, in contrast to the cooler/lunch bags with fixed liners, which become disposable when soiled.
US09938067B2 Microwave packaging
A container for heating a food product with microwave energy having a wavelength. The container can include a generally circular centerline having an axis, and a receptacle including a sidewall extending at least partially around a cavity. At least a portion of the cavity can extend along at least a portion of the centerline. The sidewall can include an inner edge and an outer edge each being spaced apart from the axis of the centerline for at least partially retaining the food product in the cavity in proximity to the centerline.
US09938065B2 Packaging for tool handle with internal storage cavity and removable cap
A tool packaged for retail sale has a tool handle including a handle outer surface and an internal storage channel within the handle and having a channel opening facilitating selective access to the storage channel. A removable handle cap with a cap-exterior surface is installed over the channel opening in order to close off the storage channel. The handle cap is retained in place by a cap-restraining strip fabricated from a tear-resistant material. More specifically, a central portion of the cap-restraining strip is disposed over at least a portion of the cap-exterior surface, while portions of the cap-restraining strip on opposite sides of the central portion are disposed to extend along mutually opposite sides of the handle outer surface. A wrapper securely binds the portions of the cap-restraining strip located on opposite sides of the handle outer surface, thereby preventing removal of the handle cap without destruction of the wrapper.
US09938063B2 Package for storing a plurality of products
A package kit includes a plurality of primary packages, each having a cavity for storing one of a plurality of products, and a secondary package that stores the plurality of primary packages and includes a back and front panels between which the primary packages are sandwiched. The front panel has a first row of apertures, each displaying at least a portion of a primary package. A first outer circumferential portion of the front panel partially surrounds the apertures and is attached to the back panel, and a second outer circumferential portion of the front panel is attached to the back panel. The front panel includes an elevated portion between the first and second outer circumferential portions. The first outer circumferential portion has a first and second limbs, and the second outer circumferential portion has a third and fourth limbs. The elevated portion extends from, and is hingeably connected to, the first, second, third, and fourth limbs.
US09938062B1 Elastic tie and methods of using and manufacturing the same
Tying devices, and methods of using and manufacturing the same are provided. The tying devices can include an elastic band having at least one elongated malleable member attached to at least one end thereof. When the tying devices are wrapped about an object, under tension, in self-overlapping configuration, and the elongated malleable member is bent to approximate a surface contour of the object, even without wrapping the malleable member fully around the object, the combination of friction between the overlapping surfaces of the elastic band, and the rigidity of the elongated malleable member, can be sufficient to retain the tying device securely under tension.
US09938060B2 Container and lid locking mechanism thereof
A container lid locking mechanism and a container. The container is provided with a base (3), side boards (2), and a lid (1). The locking mechanism comprises buckles (6), return members (7), recesses (8), openings (11), and locking holes (10). The recesses (8) and the openings (11) are located in the edge of the lid (1), and the locking holes (10) are located in the side boards (2). Each of the buckles consists of a buckle body and a tongue (61) extending out from the buckle body. The return members (7) can enable the buckles (6) to be kept in a locked position. The recesses (8) are used for accommodating the buckle bodies. Two pairs of limit structures are disposed on the buckles (6) and in the edge recesses (8) of the lid (1). When the locking mechanism locks, the pair of limit structures (13, 66) on the buckles (6) and the lid (1) are in a fitted state to limit the buckles (6). The tongue (61) penetrates through the opening (11) at the edge of the lid (1) and is fastened into the locking hole (10) in the side board (2). When the locking mechanism is in an unlocked state, the other pair of limit structures (16, 63) on the buckles (6) and the lid (1) are in a fitted sate to limit the buckles (6), and the tongue (61) exits from the locking hole (10) in the side board (2).
US09938059B1 Bottled beverage illumination device
A bottled beverage illumination device includes an elongated transparent or translucent rod partially secured at a first end within a cork assembly. Above the cork assembly is housing that retains an illumination means in electrical communication with a power source and switch. At least one (1) embodiment of the device includes a cap with a fastener located on the cork assembly for removable attachment to a beverage container.
US09938057B2 Preservation device
A preservation device are used to preserve liquids and other items, such as foodstuffs, which spoil when exposed to oxygen for a period of time. The preservation devices are configured to form an air tight seal when disposed on a bottle and/or a vessel. The devices include a container, and disposed within the container is an oxygen absorber, which removes oxygen remaining in the bottle or vessel after it is sealed by the preservation device. Either the container or the oxygen absorber has a gas permeable, liquid impermeable membrane. The preservation device may also include a flow control mechanism that enables a liquid to be dispensed from the bottle without requiring the removal of the entire stopper device from the bottle. The preservation device may alternatively include an air channel system to control the flow of the liquid to be dispensed from the bottle without requiring the removal of the entire stopper device from the bottle. Such arrangements enable the liquid to be dispensed while only allowing a minimal amount of oxygen to enter the bottle, thus improving preservation.
US09938052B2 Safety mechanism for containers
A container top comprising a container top member comprising tracks over an upper surface thereof and a sealer sealing an opening thereof; and a slidable member having a sealing mechanism, the slidable member being slidable through the tracks and positioned such that sliding of the slidable member over the tracks to one direction unseals the sealer, forming an opening over the container top member, in the initial opening thereof and wherein sliding the slidable member back to its original position over the opening formed thereby covers and seals the opening. The opening formed by the unsealing of the sealer can be re-sealed at will by the sealing mechanism of the slidable member. The sealing mechanism may be for example a sealing material coating strip located over a periphery of the slidable member or the physical configuration of the slidable member periphery edges.
US09938050B2 Closure with hinged tamper band
A container assembly including a pouch, spout and closure is provided. The closure includes a tamper-evident band having two or more wall sections. Adjacent wall sections of the tamper band may be connected to one another with frangible connectors configured to break upon twist-off of the closure from the spout. The closure also includes one or more support walls supported between an outer wall and central wall of the closure. The closure further includes one or more hinges attaching the ends of the wall sections of the tamper band to the lower ends of the support walls. The hinges are configured to increase the resistance required to break or otherwise distort the frangible connections of the tamper-evident band, so as to prevent or lower the risk of accidental or inadvertent breakage of the tamper-evident band prior to twist-off of the closure from the spout.
US09938049B2 Metal cap having foamed coating film and method for manufacturing same
A metal cap has an outer surface with a coating film including a coating composition containing thermally expandable hollow particles in a paint, the curing initiation temperature TA (° C.) of the paint, expressed as a temperature where an attenuation rate by a rigid pendulum viscoelasticity test reaches an inflection point, satisfies TA≥Ta+25 Ta being the expansion initiation temperature (° C.) of the thermally expandable hollow particles, and the maximum curing temperature TB (° C.) of the paint, expressed as a temperature where the attenuation rate by the rigid pendulum viscoelasticity test reaches a peak, satisfies Tb−10≤TB≤Tb+10 Tb being the maximum expansion temperature (° C.) of the thermally expandable hollow particles. Because of these features, a metal cap is excellent in grip and openability even when dew condensation occurs, and is also excellent in scratch resistance, is provided with high efficiency.
US09938040B2 Blanks and methods for forming a shelf-ready display container
A blank of sheet material for forming a container includes a front panel, a top panel, a rear panel, and a bottom panel coupled together in series by a plurality of generally parallel fold lines. The blank also includes a pair of front side panels extending from opposing side edges of the front panel, a pair of top side panels coupled to opposing side edges of the top panel, and a pair of bottom side panels coupled to opposing side edges of the bottom panel. A side tab extends from each bottom side panel along a tab perforation line. Each side tab is configured to couple to one of the front side panels in a face-to-face relationship. A face of each of the top panel, the bottom panel, the pair of top side panels, and the pair of bottom side panels is devoid of perforation lines extending therethrough.
US09938037B2 Package with flip-open closure
A package for containing items having a flip-open package closure is provided. In some embodiments, the package includes a rigid package body and a flexible closure flap. The flexible closure flap is coupled to a hangtab portion of the package body such that the flexible closure flap moves from a closed position to an open position with respect to the package body based on a position of the hangtab portion. An upper edge of a front side of the package body engages the lower portion of the closure flap when the package is closed, while the lower edge of the closure flap is released from the upper edge upon pivoting backward of the hangtab portion. Such pivoting of the hangtab portion, and corresponding manipulation of the closure flap, may occur without directly contacting the closure flap.
US09938033B2 Sonotrode
A sonotrode that includes a sealing face; a front quarter wavelength region adjacent to the sealing face, wherein the front quarter wavelength region has been modified to increase the gain of the sonotrode; and a rear quarter wavelength region adjacent to the front quarter wavelength region, wherein the rear quarter wavelength region has been modified to create a non-uniform amplitude profile across the length of the sealing face of the sonotrode.
US09938032B2 Modular ultrasonic device for use in package sealing systems
An ultrasonic module for use in package sealing systems that includes a moveable front jaw; an elognated sonotrode disposed within the front jaw, wherein the sonotrode includes an elongated sealing face, and wherein the width of the sealing face is at least 12 inches (30.48 cm); a moveable rear jaw; and an anvil mounted on the rear jaw opposite the sonotrode, wherein the anvil mechanically cooperates with the sonotrode to seal a package.
US09938028B2 Stretch packaging machine
A stretch packaging machine is provided with a lift mechanism and a tray movement mechanism. The lift mechanism has a plurality of loading members on which a tray is loaded and which lift up the tray toward film such that the tray contacts the film sealing an opening at the top of the tray. The tray movement mechanism is configured to move the tray slidingly over the loading members of the lift mechanism to a predetermined position on the loading members. A frictional coefficient of at least first loading members is such that contact between the tray and the loading members disposed on the near side in the moving direction in which the tray is moved by the tray movement mechanism is smaller than the frictional coefficient of second loading members disposed on the far side in the moving direction.
US09938024B1 Object redirection using energetic pulses
An object redirection system may generate a high-resolution three-dimensional map of a surface of a target. Based on the map, the system may identify locations on the target's surface and direct energetic pulses toward the target at the locations. The system may continuously update the map of the target and continue emitting pulses at the target with reference to the map in order to achieve a desired velocity of the target within a desired timeframe.
US09938023B2 System and method for an integrated satellite platform
A system, method, and computer-readable storage devices for a 6U CubeSat with a magnetometer boom. The example 6U CubeSat can include an on-board computing device connected to an electrical power system, wherein the electrical power system receives power from at least one of a battery and at least one solar panel, a first fluxgate sensor attached to an extendable boom, a release mechanism for extending the extendable boom, at least one second fluxgate sensor fixed within the satellite, an ion neutral mass spectrometer, and a relativistic electron/proton telescope. The on-board computing device can receive data from the first fluxgate sensor, the at least one second fluxgate sensor, the ion neutral mass spectrometer, and the relativistic electron/proton telescope via the bus, and can then process the data via an algorithm to deduce a geophysical signal.
US09938022B2 Fueling nozzle adapter
A nozzle adapter for coupling a fueling nozzle to an underwing type servicing adapter having a radially outward extending tab and a notch formed in an open end thereof comprises an outer body including a neck portion having a first conduit formed therein and a substantially cylindrical cap portion, the cap portion including at least one slot formed therein. An inner body has a second conduit formed therein and is disposed within the cap portion of the outer body and an annular channel is formed between the cap portion and the inner body. The at least one tab is received in the at least one slot and a rotation of the nozzle adapter relative to the servicing adapter causes a first aperture configured to receive a locking device therein to be aligned with the at least one notch of the servicing adapter.
US09938020B2 Laser-based tail dock anti-collision system and method to preclude damage to aircraft upon their insertion into maintenance facilities
A tail dock anti-collision system for augmenting positioning of an aircraft in a maintenance facility which comprises lateral alignment sensors disposed on opposing sides of the aircraft and a backup tracking sensor directed toward the tail section. A processor, for example a programmable logic controller, is coupled to, and operatively controls, the sensors to provide an indication to a principal guide of the aircraft docking procedure of the relative position of the aircraft with respect to a centerline and platform of the maintenance facility.
US09938019B2 Systems and methods for detecting a security breach in an aircraft network
A network system of an aircraft implements a target system to attract, detect, log, and mitigate a potential breach by the malicious entities. The target system simulates the systems of the aircraft in order to attract a potential breach. The target system simulates the data, file structure, communications, etc., of the systems of the aircraft. The target system includes little, or no security or access controls in order to attract a potential breach and allow the malicious entity to gain access. Once a breach occurs, the target system can be configured to log, report, and/or mitigate the potential breach.
US09938014B2 Video display unit cassette assemblies for aircraft seats and enhanced in flight entertainment user experience
A video display unit cassette assembly includes a cassette frame, a display coupled to the cassette frame, one or more electronic components between the cassette frame and the display, and a delethalization cover coupled to the display. The one or more electronic components receive data content from a network and generate video signals provided to the display. The cassette assembly is sized and configured to be releasably mounted in an installed position in a mounting structure defined in a seatback of a vehicle seat.
US09937994B2 Method and apparatus for controlling a marine vessel
One embodiment of the invention comprises a method for controlling a marine vessel having a first steerable propulsor, a corresponding first reversing device, a second steerable propulsor and a corresponding second reversing device. The method comprises receiving a first vessel control signal corresponding to a rotational movement and no translational movement command, generating at least a first actuator control signal and a second actuator control signal in response to the first vessel control signal, coupling the first actuator control signal to and controlling the first steerable propulsor and the second steerable propulsor, and coupling the second actuator control signal to and controlling the first reversing device and to the second reversing device. The method creates rotational forces on the marine vessel with substantially no translational forces on the marine vessel.
US09937992B2 Steering device and method for steering the same
A steering device having two rudder plates vertically suspended at a distance from an outer edge of a propeller. The rudder plates are biaxially arranged and symmetrically rotate around a screw shaft within a propeller radius from a screw shaft center, on a propeller rotation plane, and are turned from aside the propeller to downstream of the propeller by rotation of the steering shafts, each of which is driven independently by two hydraulic driving mechanisms. The steering action of the steering device has two modes: the two-independent mode, where the plates rotate in the same direction, and the two-same direction modes, where the plates move in different directions. A method for steering the same to enhance a thrust flow by increase in a propeller rate is also provided.
US09937989B2 Outboard motor
An outboard motor includes an engine housed in a cowling and disposed above an upper case housing a driveshaft. A gear mechanism transmits a rotation of the driveshaft to a propeller shaft housed in a lower case disposed below the upper case. The gear mechanism is housed in an oil storage chamber of the lower case and is lubricated by a lubricating oil inside the oil storage chamber. An oil passage includes a lower oil port opening at the oil storage chamber, an upper oil port positioned higher than the lower case, and a longitudinal passage extending in an up/down direction inside the lower case.
US09937988B2 Outboard motor power generation system and outboard motor
An outboard motor power generation system includes an engine, a power generator, a converting device configured to convert alternating-current power into direct-current power, an engine cover configured to cover the engine, the power generator, and the converting device, a battery, and a transformer provided on an electric pathway between the converting device and the battery and configured to raise the voltage of the direct-current power output from the converting device relative to the charge voltage of the battery.
US09937985B2 System and method for planning and predetermination of fender heights and dock location information
A system for planning and predetermination of boat fender heights and dock location information, comprising a boat fender controller configured to calculate a required fender deployment height prior to arrival at a predetermined dock location, based on real-time information, and to raise or lower a plurality of boat fenders based on the calculated fender deployment height on final approach to the predetermined dock location.
US09937979B1 Manual submersible auxiliary swim platform for vessels
A manual and submersible auxiliary swim platform for a vessel having a main aft platform, the main aft platform having a recessed area for receiving the auxiliary swim platform. A pair of bracket assemblies secure the auxiliary platform to the main aft platform, and both bracket assemblies have a first bracket member, a second bracket member, and a detent bushing. The detent bushing is interposed and secured to the first and second bracket members at a common end. The detent bushing limits rotational and pivotal movement of the bracket assemblies in conjunction with a contact tab, pin and channel design of the bracket assemblies.
US09937975B2 Convertible motorized running cycle
A convertible running bike capable of selectively converting from a non-motorized configuration to a motorized configuration may include a front fork rotatably engaged with a front wheel, a handle bar rotatably engaged with the front fork for steering the bike, a frame and a seat connected to the frame.
US09937974B2 Three-wheeled rear-steering scooter
A three wheeled scooter comprises a chassis having forward and aft ends with a front wheel non-pivotally mounted to the forward end and a pair of rear wheels coaxially mounted to the aft end. The chassis defines a longitudinal axis and includes a support assembly and a handle assembly extending upwardly from the support assembly. The rear wheels are configured to be angularly yawable relative to the longitudinal axis between a neutral position and a yawed position. Steering of the scooter is thereby effectuated by angular yawing of the rear wheels relative to the longitudinal axis such as by asymmetric loading of one of opposing sides of the support assembly.
US09937971B2 Saddle adjustment system
A bicycle assembly comprises a saddle adjustment assembly, the saddle adjustment assembly comprising an adjustable height saddle post, the adjustable height saddle post comprising first and second slidably coupled supports; a saddle post locking mechanism that selectively restricts sliding of the second support relative to the first support; and a saddle angle adjustment mechanism configured to couple to a bicycle saddle to enable rotation of the bicycle saddle between a first predetermined position and a second predetermined position, wherein, when the saddle post locking mechanism is in an unlocked configuration, the saddle angle adjustment mechanism enables rotation of the bicycle saddle between the first and second predetermined positions, and wherein, when the saddle post locking mechanism is in a locked configuration, the saddle angle adjustment mechanism maintains the bicycle saddle in one of the first and second predetermined positions.
US09937970B2 Method for manufacturing telescopic shaft
A telescopic shaft includes a hollow outer shaft, an inner shaft spline-fitted to the outer shaft, a resin coating provided on splines on at least one of the outer and inner shafts, and can be extended and contracted in an axial direction. A method for manufacturing the telescopic shaft includes press-fitting the inner shaft into the outer shaft and sliding one of the outer and inner shafts relative to the other of the outer and inner shafts by reciprocating the one shaft in the axial direction. In the sliding, a frequency according to a sliding speed at which the one shaft is slid relative to the other shaft is set to be lower than a predetermined value at the start of sliding, and the frequency is increased in a continuous or stepwise manner when a sliding load of the one shaft to the other shaft is reduced.
US09937968B2 Stackable vehicle
A stackable vehicle is provided and includes a deck, pairs of controllable support elements at each of a first pair of opposed minor surfaces of the deck and comprising a first leg affixed to the deck and transversely telescopic relative to a corresponding minor surface plane, a second leg coupled to a distal end of the first leg and telescopic in parallel with the corresponding minor surface plane and a pivotable and rotatable wheel disposed at a distal end of the second leg and pairs of controllable support elements at each of a second pair of opposed minor surfaces of the deck and comprising a first leg affixed to the deck, a second leg coupled to a distal end of the first leg and telescopic in parallel with a corresponding minor surface plane and a pivotable and rotatable wheel disposed at a distal end of the second leg.
US09937966B1 Apparatus for improving aerodynamic performance of vehicle
An apparatus is configured such that the outer shape of a shape memory material is transformed or changed to be enlarged or decreased in conjunction with vehicle speed and at that time a deflector 30 is actuated to move up and down to actively improve aerodynamic performance of a vehicle.
US09937963B2 Automated drag reduction in moving objects
A system for reducing drag on a vehicle body moving through fluid includes a sensor mounted on the vehicle body for measuring data adjacent to the vehicle body surface, an eddy disrupter element mounted on the vehicle body for motion to a transverse position relative to the plane of the vehicle body surface and a processor for facilitating a comparative analysis of the measured data with a threshold condition to determine if the threshold condition is satisfied, wherein the threshold condition is associated with drag resulting from the vehicle body movement through the fluid that can be reduced by the motion of the eddy disrupter element to a transverse position relative to the plane of the vehicle body surface and wherein the element is responsive to satisfaction of the threshold condition.
US09937962B1 Truck bed extension system
A truck bed extension system for increasing a height of a truck bed includes a vehicle that has a bed. A plurality of wall units is provided and each of the wall units is removably coupled to the bed. Each of the wall units is vertically oriented on the top edge such that each of the wall units increases a depth of the bed. In this way the bed may carry an object that would otherwise be too tall.
US09937959B2 Mud flap system
A mud flap system for a tractor is described. The mud flap system includes brackets that clamp or secure to a frame of the tractor. Lateral extensions engage to the brackets to support covers over a top surface of rear wheels of the tractor.
US09937953B2 Trailer backup offset determination
A system for calibrating a backup assist system for a trailer attached to a vehicle is provided which includes a hitch sensor continuously measuring a hitch angle for determining an angle rate, a yaw sensor continuously sensing a yaw rate of the vehicle, and a controller configured to determine an offset of the measured hitch angle when vehicle is driving forward and/or rearward.
US09937952B2 Vehicles and vehicle systems for restricting rotation of a vehicle steering system
Vehicles and vehicle systems for restricting rotation of vehicle steering systems are disclosed herein. In one embodiment, a vehicle including a front wheel, a steering column assembly coupled to the front wheel, a steering wheel coupled to the steering column assembly, a steering rack assembly that includes a rack coupled to the front wheel, where the rack extends in a vehicle lateral direction and is translatable with respect to a body of the vehicle in the vehicle lateral direction, and a resistance device including a damper coupled to at least one of the steering rack assembly and the steering column assembly that limits a rotation of the steering column assembly.
US09937951B2 Determination of an angular reference position of a power steering system from rising and falling edges of an index signal
A reference position in a power steering system is defined by acquiring a first edge position corresponding to a first edge of a first index pulse generated when a movable steering member passes an indexed position in a first movement direction; acquiring a second edge position corresponding to a second edge of a second index pulse generated when the movable steering member passes the same indexed position in a second movement position opposite the first movement direction; and calculating the reference position from the first edge position and the second edge position.
US09937948B2 Steering input apparatus for vehicle and vehicle
A steering input apparatus for a vehicle includes a grip position sensor configured to sense a grip position on a rim of a steering wheel of the vehicle. The steering input apparatus also includes at least one processor configured to, based on a determination that the grip position on the rim of the steering wheel sensed through the grip position sensor is improper for a driving situation of the vehicle, perform a control operation to output grip guide information for the rim of the steering wheel.
US09937946B1 Compact universal infant carrier transporting device
The present invention is a compact universal infant carrier transporting device which is used to transport most infant carriers/car seats from one point to another with ease with the infant secured in the carrier. The device's portability and size allows for use in the smallest of spaces and allows users to avoid having to manually hold a heavy infant and carrier/car seat combination. The core components of the invention are a collapsible patio chair style frame supported on wheels. The frame supports a fabric base having an opening therein for receiving the carrier/car seat. A strap is provided to secure the carrier to the device, and a foot brake is provided on at least one of the wheels. The device folds so that it can be stored in a bag similar to a bag similar to those used for a folding patio chair.
US09937944B2 Dolly for moving objects
A dolly capable of allowing relatively heavy and bulky objects to be easily manipulated and moved without adding significantly to the dimension of the object thereby allowing the object to be easily moved through conventional door openings. Preferably, the dolly comprises a first frame having generally vertical legs mechanically coupled to a generally horizontal brace and a second frame having generally vertical legs mechanically coupled to a generally horizontal brace such that the first frame and the second frame are in position on opposite sides of the object and the generally horizontal braces are positioned under corresponding edges of the object. The generally vertical legs of the first frame and the second frame when moved into a more vertical orientation operate to mechanically lift the generally horizontal braces to lift the object and allow the object to be transported to a desired location.
US09937941B2 Takedown utility cart
A takedown utility cart includes rectangular platforms each having four corners, each platform including a main panel having four beams; four sets of post sections, each set secured through one corners of the platforms; two side walls each threadedly fastened between sides of two adjacent platforms; a rear panel having two sides threadedly secured to rear ends of the side walls respectively so that an open space is defined by the platforms, the side walls, and the rear panel; at least one drawer retractably mounted in the space; and a lock assembly mounted on the rear panel for locking or unlocking the drawer.
US09937940B2 Apparatus for generating action recommendations for the driver of a rail vehicle
An apparatus for generating action recommendations for the driver of a rail vehicle includes a device that can be carried by the driver in order to provide a type of apparatus that can be retrofitted quickly and easily to an existing rail vehicle. The device has at least one data interface unit for receiving basic data, a memory unit for storing at least one program module, a processing unit provided for executing the program module in order to generate the action recommendations at least on the basis of the basic data, and an output unit for outputting the action recommendations. A rail vehicle having the apparatus is also provided.
US09937939B2 Railway vehicle operation
A method of operating a railway vehicle on a network of tracks forming one or more vehicle routes, includes providing: vehicle status information including the present track location of the vehicle, the route to be taken by the vehicle and operation profile information relating vehicle operational recommendations and/or requirements to track locations and to vehicle routes; and determining operational risks for the vehicle from the vehicle status information, the route to be taken by the vehicle and the operation profile information, each operational risk being the likelihood of future vehicle operation departing from the operation profile information at a given section of track or a given location on the route. Advisory notices for a driver of the vehicle are generated on the basis of the operational risks, and each advisory notice, when acted on by the driver, reduces the likelihood of future vehicle operation departing from the operation profile information.
US09937934B2 Coupling head of a central buffer coupling
A coupling head for a central buffer coupling for vehicles that are able to be coupled has a coupling head housing and an end plate that terminates the coupling head housing on the end face and is releasably connected to the coupling head housing. The coupling head housing has a first connection region for coupling to the end plate and a second connection region for establishing the connection to a coupling rod. The coupling head housing is designed in one piece as a forged component. The first connection region is formed on the coupling head housing by at least two contact surfaces arranged separately from one another in order to be at least indirectly supported on partial surfaces of the end plate and the coupling head housing is connected to the end plate in the first connection region by non-positive connections.
US09937933B2 High level platform trapdoor with built in moving slide for railway platform gap bridging
A trapdoor assembly for use on railcars is provided. The trapdoor assembly is pivotable between an up position and a down position. In the up position, the trapdoor assembly provides access to stairs on the railcar so that passengers can egress between the railcar and a ground level platform at a rail station. In the down position, the trapdoor assembly covers the stairs and provides a platform so that passengers can egress between the railcar and an elevated platform at a rail station. The trapdoor assembly also includes an extendible platform for bridging the gap between the railcar and the elevated station when the trapdoor is in the down position and the railcar is stopped at the elevated station.
US09937932B2 Method and system for using dynamic boundaries to manage the progression of ride vehicles that have rider control inputs
A method for controlling vehicle progression along a ride path of an amusement park ride. The method includes receiving inputs from a passenger of a vehicle on the ride path and processing the received inputs to determine a vehicle state change. The method includes determining a present or predicted vehicle state and comparing the present or predicted vehicle state with constraints defined by a dynamic boundary associated with the vehicle. The method includes issuing vehicle control commands to a drive assembly to implement the vehicle state change if it complies with the constraints. The dynamic boundary is moved logically along the ride path at a nominal to define a set of boundaries for movement of the vehicle along the ride path. The vehicle state change may be a change that causes the vehicle to travel at a speed differing from the dynamic boundary while remaining within the dynamic boundary.
US09937929B2 Method and device for operating a motor vehicle that drives or is able to be driven in an at least partially automated manner
A method for operating a motor vehicle which drives or is able to be driven at least partially automatically includes: detecting a gaze direction of a driver of the motor vehicle; inferring a driver distraction if the detected gaze direction deviates from a setpoint gaze direction beyond a predefinable measure; monitoring the driver for a secondary activity if a distracted driver was detected; and ascertaining a time period that the driver would require to take over the at least partial control of the motor vehicle, as a function of a detected secondary activity.
US09937924B1 Modifying a vehicle state based on the presence of a special-purpose vehicle
A method is provided that includes receiving user input identifying a travel destination for a first vehicle, determining, by a processor, a first route for the first vehicle to follow, and configuring the first vehicle to follow the first route. The method further includes obtaining a model for a second vehicle that shares a road with the first vehicle and comparing model to a pre-determined template for a vehicle that is known to be a special purpose vehicle in order to determine whether the first template and the second template match. The method further includes determining, by the processor, a second route that leads to the travel destination, when a match is found to exist, and switching the first vehicle from following the first route to following the second route.
US09937922B2 Collision avoidance using auditory data augmented with map data
A controller for an autonomous vehicle receives audio signals from one or more microphones and identifies sounds. The controller further identifies an estimated location of the sound origin and the type of sound, i.e. whether the sound is a vehicle and/or the type of vehicle. The controller analyzes map data and attempts to identify a landmark within a tolerance from the estimated location. If a landmark is found corresponding to the estimated location and type of the sound origin, then the certainty is increased that the source of the sound is at that location and is that type of sound source. Collision avoidance is then performed with respect to the location of the sound origin and its type with the certainty as augmented using the map data. Collision avoidance may include automatically actuating brake, steering, and accelerator actuators in order to avoid the location of the sound origin.
US09937915B2 Hybrid vehicle
In a hybrid vehicle, in double-drive mode of an electric drive mode, in which the hybrid vehicle travels by using two motors, that is, a first motor and a second motor, in a state where execution of vibration damping control with the use of the second motor is being required, when it is possible to output a total torque, which is the sum of a second distribution torque and a vibration damping torque, from the second motor to a drive shaft, the vibration damping control with the use of the second motor is executed; whereas, when it is not possible to output the total torque from the second motor to the drive shaft, vibration damping control with the use of the first motor is executed.
US09937912B2 Transportation system including a hovering vehicle
A transportation system is disclosed. The transportation system has a vehicle that is self-powered and configured to generate an air cushion on a trackless lane having a substantially flat surface. The vehicle is configured to move over the substantially flat surface on the air cushion. The transportation system also has a guidance system configured to guide the vehicle between peripheries of the trackless lane.
US09937910B2 Braking system and method of operating the same
A braking system includes a master cylinder including a master cylinder output, at least one wheel cylinder, a shuttle valve including a shuttle, a volume booster distinct from the master cylinder, a first hydraulic fluid path connecting the master cylinder output to the at least one wheel cylinder through the volume booster and the shuttle valve and a second hydraulic fluid path connecting the master cylinder output to the at least one wheel cylinder through the shuttle valve, bypassing the volume booster. Only one of the first hydraulic fluid path or the second hydraulic fluid path is operable at any one time.
US09937906B1 Vehicle garage warning system
The present invention relates to a system and method of detecting if a garage door is open, in order to prevent a vehicle which is leaving the garage from hitting the door or approaching the door before it is sufficiently open enough for the exiting vehicle to clear the door.
US09937905B2 Side collision avoidance system and method for vehicle
A side collision avoidance system and method for a vehicle combines data from radar sensors mounted on front and rear surfaces of the vehicle with data from ultrasonic sensors mounted on side surfaces of the vehicle, and detects obstacles on the basis of the combined data, so as to increase accuracy in the detection of obstacles and predict the probability of collisions with obstacles with high accuracy. The system includes: radar sensors detecting an obstacle around the vehicle; ultrasonic sensors detecting the obstacle around the vehicle; a controller combining sensor data from the radar sensors with sensor data from the ultrasonic sensors to generate combined data, detecting the obstacle on the basis of the combined data, and predicting collision or non-collision with the detected obstacle on the basis of the combined data; and a brake driver braking the vehicle when the collision is predicted.
US09937902B2 Landing gear with cross-port disable valve and supplemental electronic limit switch travel limiter
A travel limiter for landing gear extension legs which employs a pair of mechanically-operable cross-port valves fluidly coupled to the hydraulic circuit, and a pair of supplemental electronic limit switches electrically coupled to the drive motor of the hydraulic circuit, that are operably synchronized for mechanical actuation based on movement of the telescoping upper and lower leg assemblies of the landing gear between respective extend and retract travel stop limit positions. Upon reaching a travel stop limit position, a cross-port valve partially diverts the system's fluid flow away from the drive motor until a limit switch is actuated to cut electrical power and stop fluid flow through the drive motor. If the limit switch fails, the valve completes the fluid flow bypass, thereby permitting all fluid flow to bypass the drive motor and disable the landing gear prior to reaching its final mechanical stop.
US09937901B2 Jack for ATV
An ATV jack may include a clamping engagement member and a leg which pivots which respect to the clamping engagement member a limited amount to enable the jack to lift and hold an ATV. The leg may telescope to allow the jack to be used at variable heights.
US09937900B2 On-board vehicle vacuum cleaner system
An on-board central vacuum system includes a vacuum motor assembly, a first vacuum port assembly and a connecting hose. The first vacuum port assembly is configured in a first location of the vehicle. The first vacuum port assembly includes a recess formed in vehicle trim and a cup holder. The recess defines a first port. The cup holder is removably positioned in the recess. The cup holder is movable between and installed position and a removed position. In the installed position the cup holder is received by the recess and blocks access to the first port. In the removed position, the cup holder is removed from the recess revealing access to the first port. The connecting hose fluidly connects the vacuum motor assembly to the first port.
US09937899B2 Wiper arm and vehicle wiper apparatus equipped therewith
A wiper arm comprising an arm main body; a first nozzle portion disposed at a first predetermined position in a length direction of the arm main body; a second nozzle portion disposed at a second predetermined position in the length direction of the arm main body, and jets washing fluid toward a position that is different from an impact point of the washing fluid jetted from the first nozzle portion; a first line hose accommodated in the arm main body and connected to the first nozzle portion; a second line hose accommodated in the arm main body side-by-side with the first line hose and connected to the second nozzle portion; and a hose retention unit attached to the arm main body and that comprises: a first hose retention portion retaining the first line hose; and a second hose retention portion provided integrally with the first hose retention portion and retaining the second line hose.
US09937897B1 Wiper blade-lifting system
The wiper blade-lifting system comprises a wiper arm with a motorized mechanism to cause the wiper blade to bend at a hinge point responsive to the presence of electrical power. The wiper blade-lifting system is useful to lift a wiper blade off the surface of a windshield when ice or freezing rain is anticipated, so that the wiper blade does not become frozen in place against the surface of the windshield. A second activation of the wiper blade-lifting system using electrical power of the opposite polarity causes the wiper blade to straighten and place the wiper blade back in contact with the windshield. The application of electrical power to the wiper blade-lifting system may be under control of an interior lift control or, in some embodiments, a blade lift remote control.
US09937896B2 Motor vehicle having a lamp in an antenna device for signaling the operating condition of a security system
A motor vehicle having a security system includes a first lamp for indicating the operating state of the security system, and an antenna device which is supported by the body of the motor vehicle and is arranged outside the vehicle body. The first lamp is integrated into the antenna device.
US09937889B2 Vehicle partition
A partition for a vehicle is described. The partition separates the cargo area of the vehicle from the cab area of the vehicle. The partition may extend from floor to roof and from one side of the vehicle to the other side of the vehicle. The partition has a window so that the driver can see into the cargo portion. The window is positioned to ensure the driver can see through it in a variety of conditions.
US09937883B2 Bumper guard utilizing adjustable tabs
A one-size fits-all protector for one of an any length front bumper cover of a vehicle and an any length rear bumper cover of the vehicle. The any length front bumper cover has a top and a pair of sides. The any length rear bumper cover has a top and a pair of sides. The vehicle has a grille, a pair of front wheel wells, a trunk, and a pair of rear wheel wells. The one-size fits-all protector includes a body and an attaching apparatus. The body overlies and protects by being length adjustable one of the any length front bumper cover and the any length rear bumper cover. The attaching apparatus replaceably attaches the body to the one of the any length front bumper cover and the any length rear bumper cover.
US09937878B2 Load compartment cover having sound-absorbing characteristics
The invention relates to a load compartment cover having sound-absorbing characteristics. A load compartment is provided between the rear seats and a tailgate. The load compartment cover is embodied from a sound-absorbing partition that is arranged in a space above a base of the load compartment and is embodied from a material that is in part permeable to sound waves. A load compartment cover of this type is to be easily handled in practice and is not to comprise any disadvantages associated with known load compartment covers. This is achieved by virtue of the fact that the partition is formed from multiple, preferably two, thin sheets that are arranged spaced apart one above the other. The thin sheets are provided with a micro perforation and only one air cushion is provided between the thin sheets.
US09937874B2 Vehicular display apparatus
A vehicular display apparatus is provided on a vehicular instrument panel and provides a display for a vehicular crew. The apparatus includes: a half mirror that transmits light from a front of a vehicle to a back of the vehicle and reflects light from a direction intersecting with a front-back direction of the vehicle to the back of the vehicle, a decorative member provided to one side of a side of the front of the vehicle and a side of the intersecting direction, a light emitting member that irradiates the decorative member with light, and a liquid crystal display that is provided to the other side and projects an image toward the half mirror. The decorative member is arranged so as to provide a display superposed on the image projected by the liquid crystal display when visually recognized from a front side.
US09937873B2 System, enclosure and method for deployment of audio visual equipment from a vehicle as a base
A system for deployment of audio and/or visual components from a vehicle as a base, the system comprising a housing configured to be held during transport in the vehicle, a movable lid attached to the housing, one or more arms attached to the housing and configured: (i) to be enclosed within the housing when the lid is closed, and (ii) to mechanically deploy to a position outside of the housing by moving out of the housing when the lid is open. The system may further include one or more speakers mounted on or embedded within the one or more arms, and a processor configured to automatically: (i) open the lid, and (ii) mechanically deploy the one or more arms.
US09937870B1 Motor vehicle with integrated bike rack
A motor vehicle is provided incorporating an integrated bike rack. That bike rack includes a support arm, a first sill segment that is received in a slot and aligned with a closure sill of the motor vehicle when the bike rack is in a stowed position and a second sill segment that is received in a slot and aligned with the closure sill when the bike rack is in a deployed position. A related method is also disclosed.
US09937869B2 Vehicle storage box incorporating a standard interface plate connection
A vehicle-bed storage box includes a container having an interior volume, an interface plate disposed within a vehicle-bed sidewall that selectively receives the container against the vehicle-bed sidewall and over a vehicle-bed wheelhouse, the interface plate including a securing recess and an interface bracket extending from at least one sidewall, the interface bracket including a rotating mechanism operable between a plurality of rotational positions, including an engaged position and a secured position when the interface bracket is received by the interface plate, the engaged position being defined by the rotating mechanism being free of engagement with the securing recess and further defined by the interface bracket being at least partially operable within the interface plate, and wherein the secured position is defined by the rotating mechanism being engaged within the securing recess and the interface bracket being substantially free of movement within the interface plate.
US09937866B2 Structure of damper for glove box
A structure of a damper for a glove box includes: a rod which has a guide provided on an upper portion thereof, and a rack gear provided along one side thereof; a housing which has a guide groove that is correspondingly coupled to the guide; a damper which is installed on the housing; a slot hole which is provided at one end of the housing and to which a rotating shaft provided on the damper is correspondingly and movably coupled; and a pinion gear which is provided at an end of the rotating shaft and engages with the rack gear.
US09937863B2 Forward viewing camera configured to control outside electro-optic mirror
A system for controlling a dimming function of a display element of a host vehicle is disclosed. The system comprises a display element configured to provide a rearward view from the host vehicle and a sensor directed forward relative to the host vehicle. A controller is in communication with the sensor and the display element. The controller is configured to identify a taillight of a detected vehicle from data received from the sensor. Based on the data received from the sensor, the controller calculates a passing period for the host vehicle to pass the detected vehicle. Based on the passing period the controller adjusts a display property of the display element to limit a glare displayed by the display element.
US09937862B2 Door mirror device for vehicle
A door mirror device includes a mirror housing mounted to a mirror base, a folding mechanism for enabling the mirror housing to pivot rearward of the vehicle when a load higher than a predetermined value is applied to the mirror housing from the front side of the vehicle. The mirror housing has a first region occupying more than half of the vertical area of the mirror housing and has a second region occupying a less area than the first region. The outer surface of the second region is located in front of the outer surface of the first region. The acute angle in a plan view between the outer surface of the second region and an outer side surface of the vehicle is greater than the acute angle between the outer surface of the first region and the outer side surface of the vehicle.
US09937860B1 Method for detecting forward collision
A safety system for an automotive vehicle includes: a dedicated radio to receive and transmit state data between a host vehicle and a remote vehicle; a global positioning system (GPS) receiver; an on-board unit (OBE) to perform a vehicle-to-vehicle (V2V) communications so that the host vehicle receives state data of the remove vehicle in a basic safety message (BSM) format; and a safety control unit. In particular, the safety control unit receives the state data of the host and remote vehicles, calculates a separation distance, a prediction horizon time, and then compares the prediction horizon time with a driver reaction time to generate a warning to a driver. More specifically, the safety control unit performs a cost value procedure when a deducted prediction horizon time is greater than zero to determine variable coefficients for estimating a future position and speed of the host and remote vehicles.
US09937859B2 Vehicle proximity indicator
Embodiments include a vehicle comprising an end facing an external object, at least one vehicle light positioned adjacent to the end and projecting a light pattern onto the object, a window adjacent to the end, and at least one proximity indicator coupled to the window at a predetermined position corresponding to an expected location of the light pattern on the object when the end is located a predetermined distance from the object. The proximity indicator can be removably adhered to the window. The light pattern can be visible through the window from a vehicle interior. In some embodiments, the object is positioned adjacent to a rear end of the vehicle and the at least one vehicle light is a rear vehicle light. In other embodiments, the object is positioned adjacent to a front end of the vehicle and the at least one vehicle light is a front vehicle light.
US09937857B2 User-configurable indication device for use with an on-demand transport service
A system and method for configuring an indication device is described. An on-demand service system arranges a transport service for a user to be provided by a driver. The system determines whether the user has specified an output configuration for an indication device in an account of the user. In response to determining that the user has specified an output configuration for the indication device, the system identifies data corresponding to the output configuration and transmits the data to a driver device of the driver to enable the driver device to control the indication device of the driver based on the data.
US09937854B2 Illuminated door handle
A door handle includes a casing inside which an accommodation space is provided, and a lamp unit disposed in the accommodation space. The lamp unit includes a light emission element, a circuit board on which the light emission element is mounted, and a combination member including a housing and a light guiding lens. The housing supports the circuit board, and the light guiding lens guides light emitted from the light emission element in a predetermined direction. In the door handle, a connection wire that supplies driving current to at least the light emission element is connected to the circuit board, and a portion of the connection wire is wound around a portion of the combination member.
US09937851B2 Device for adjusting high and low beam shape of automotive headlamp
A device for adjusting high and low beam shape of automotive headlamp comprising a fixed bracket, an adjusted assembly and an up/down and left/right adjusting mechanism. The low beam unit is disposed on the fixed bracket and the high beam unit is disposed on the adjusted assembly. The cylindrical inner hole disposed on the fixed bracket is fitted with the fixed ball head disposed on the adjusted assembly, whereas the elastic waist hole slot disposed on the fixed bracket is fitted with the adjusting bar disposed on the adjusted assembly.
US09937850B2 Automotive lamp control
Systems, methods, and computer-readable media for configuring automotive lamp illumination control are provided. One example method includes, at a computing device, generating a graphical user interface for configuring at an automotive lamp illumination pattern. The graphical user interface includes user input elements and is displayed by way of a display device. An input command is received by way of at least one of the plurality of user input elements. The input command corresponds to the at least one of the user input elements. A message is transmitted to an automotive lamp control device by way of a communication path including a first communication port of the computing device and a second communication port of the automotive lamp control device, based on the received input command. The message is received at the automotive lamp control device, and an action is performed in response to receiving the message.
US09937848B1 Mounting bracket for coupling elongate members
An assembly includes a first elongate member having a periphery. The assembly also includes a bracket. The bracket has a first component and a second component. The first component is disposed about a first portion of the periphery and the second component is disposed about a second portion of the periphery. The first component is snap-fit to the second component to secure the first elongate member between the first component and the second component. The assembly additionally includes a second elongate member coupled to the bracket.
US09937847B2 Trailers for towing vehicles and related methods
A trailer for towing vehicles and related methods is presented. The disclosed trailer can be configured for towing certain three-wheeled vehicles and include a ramp, a front wheel retaining member, and rear wheel plates. The trailer may be configured to receive a three-wheeled vehicle, and upon receipt of the front wheel at the front wheel retaining member and the rear wheels at the rear wheel plates, transition from a first position with the ramp in a lowered configuration to a second position with the ramp in a raised and locked configuration, wherein the weight of the vehicle being towed may be used to both raise the ramp and maintain the ramp in a secured, raised configuration.
US09937843B2 Apparatus for holding a liquid-filled vessel in a vehicle
An apparatus for holding a liquid-filled vessel includes a temperature sensor for sensing a temperature related to the temperature of the liquid in the vessel and a control unit connected to the temperature sensor. The control unit takes the sensed temperature as a basis for prompting an action. At a sensed temperature that is above a prescribed hot temperature limit value, the control unit then activates and/or influences a function that increases the safety of the vehicle occupant.
US09937839B2 Feedback by modifying stiffness
A system for modifying a stiffness of at least a portion of a vehicle component includes one or more devices coupled to the vehicle component and a processor coupled to the one or more devices. The processor is configured to determine that a software application has switched from a first mode to a second mode and cause the one or more devices to modify the stiffness of the at least a portion of the vehicle component from a first stiffness associated with the first mode to a second stiffness associated with the second mode.
US09937837B2 Vehicle seat
A vehicle seat includes a seat frame. The seat frame has a hollow deformable portion that is bent, and linear recessed portions formed by partially recessing an inner side of the deformable portion. The deformable portion has a linear separation portion formed in a projecting manner relative to the recessed portions and extending on the inner side of the deformable portion. A plurality of recessed portions is formed on each of one side and the other side of the separation portion so as to sandwich the separation portion, and placed independently from each other such that adjacent recessed portions are not connected to each other.
US09937834B2 Seat assembly
A seat assembly includes a seatback having a seatback body and a door pivotally coupled to the seatback body. The seatback defines an internal compartment and an opening leading to the internal compartment. The seatback defines a first seatback edge and a second seatback edge opposite the first seatback edge. The door can rotate relative to the seatback body about an axis, which extends from the first seatback edge to the second seatback edge. The door can move relative to the seatback between an open position and a closed position, and covers the opening leading to the internal compartment when disposed in the closed position. The internal compartment is accessible through the opening when the door is in the open position. The seat assembly further includes a seat base below the seatback. The first seatback edge is closer to the seat base than the second seatback edge.
US09937830B1 Child passenger safety seat emergency cooling and notification system
A system for detecting hot car seat situations, manually cooling the child in those situations, and facilitating one or more alert notifications is disclosed. An apparatus receives sensor data that it uses to detect the presence of a child in a car seat in a vehicle. Multiple sensors provide added security against false positives. When a child is detected, the apparatus activates a cooling flow of air towards the child if the temperature rises above a threshold. The apparatus waits until the vehicle is not moving and off before initiating notifications to one or more subscribing devices. Once off, and once the temperature of the child further rises or has the air flow on for a period of time, the apparatus sends a notification to the subscribing devices. If the child is not removed within a set period of time, then emergency responders are notified.
US09937827B1 Sliding armrest for vehicle
A sliding armrest for a vehicle is provided that includes a lower cover having a rotatable hook that is detachably coupled to a console and opening and closing a storage space of the console An upper cover slides between a protruding position in a length direction and an initial position and a moving part is rotatably provided at the upper cover that rotates the hook at the initial position of the upper cover to detach the hook from the console. A stopper fastens to the lower cover to restrain sliding of the upper cover or released from the lower cover by the moving part to allow the sliding of the upper cover An interlock is disposed at the upper cover and that rotates the hook corresponding to an operation of the moving part at the protruding position of the upper cover, to detach the hook from the console.
US09937823B2 Child safety seat
A child safety seat includes a seat shell, and a first and a second belt restraining member respectively connected with the seat shell. The seat shell has a shell surface, and a first and a second opening for selective passage of an anchoring belt to attach the child safety seat on a vehicle seat in two different configurations, which include a rearward and a forward facing configuration. The first belt restraining member is independently operable to press against an anchoring belt passing through the first opening, and the second belt restraining member is independently operable to press against an anchoring belt passing through the second opening.
US09937822B2 Latch in particular for a reclining backrest of a seat of a vehicle
A latch includes a support structure to be fitted to the frame (F) of a backrest of a seat; and a coupling mechanism associated with the support structure and adapted to be coupled to a fixed striker (R) in a releasable manner when the backrest is in a substantially straight position. The latch also includes an elongated member, which, on one side, is adapted to be firmly and directly coupled to the support structure and, on the other side, is adapted to be firmly and directly coupled to the frame (F), without obstructing the operation of the coupling mechanism.
US09937813B2 Vehicle
A vehicle includes an electronic control unit. The electronic control unit is configured to detect a first current value in a period in which a current path is switched to a non-conductive state by an ignition-off operation. The electronic control unit is configured to detect a second current value in a period that is after an ignition-on operation is performed and before the current path is switched from the non-conductive state to a conductive state in the case where the first current value falls out of a specified reference range. The electronic control unit is configured to diagnose that there is an abnormality of the current sensor when the second current value falls out of the reference range and to diagnose that there is no abnormality of the current sensor when the second current value falls within the reference range.
US09937809B2 Parking assistance device
A parking assistance device for aligning a vehicle coil (11) mounted on a bottom surface of a vehicle (10) with a ground coil (31) installed on a ground, detects a voltage of the vehicle coil (11), detects a change in the voltage detected, notifies a driver of first braking when the change in the voltage detected shifts from an increasing direction to a decreasing direction, and notifies the driver of second braking when the change in the voltage shifts from the decreasing direction to the increasing direction.
US09937808B2 Drone charging stations
A charging system for drones has a base structure connected to a power grid, a connector extendable from the base structure and ending in a charging interface compatible with a charging port of a drone, and a computerized controller at the base structure enabled to communicate with a drone and to initiate, control and stop charging power. As a drone approaches the charging-system, the controller directs the drone into position for charging, manages connection of the charging interface to the charging port of the drone, initiates charging power, monitors progress of charging, and upon completion of charging, disconnects the charging interface from the charging port of the drone.
US09937802B2 Systems and methods for determining a duty cycle for a variable voltage converter
A vehicle includes a traction battery, an electric machine, and a variable voltage converter. The variable voltage converter includes an inductor and is disposed electrically between the traction battery and electric machine. The vehicle also includes a controller programmed to issue duty cycle commands for the variable voltage converter based on a product of an AC component of current flowing through the inductor and a calibrated resistance.
US09937801B2 Electric motor vehicle and battery pack
An electric motor vehicle including: a high-output assembled battery; a high-capacity assembled battery having a larger capacity and a smaller output than those of the high-output assembled battery; and an inverter, and the electric motor vehicle is equipped with a PCU that transmits and receives electric power to and from the high-output assembled battery and the high-capacity assembled battery, a first wiring that connects the high-output assembled battery to the PCU, and a second wiring that connects the high-capacity assembled battery to the PCU, and is shorter than the first wiring.
US09937799B2 Pantograph down stop for trolley
A pantograph assembly configured to transfer electrical power from an overhead conductor to a machine is disclosed. The pantograph assembly may include a pantograph base detachably mounted to the machine, an articulated linkage assembly having a linkage assembly lower end operatively connected to the pantograph base and a linkage assembly upper end pivotally connected to the linkage assembly lower end, a collector rail assembly operatively connected to the linkage assembly upper end, and a stop member. The stop member may be connected to the pantograph base and engaging the articulated linkage assembly, or connected to the articulated linkage assembly and engaging the pantograph base, to prevent the articulated linkage assembly from being lowered toward the pantograph base below a predetermined down position or lower limit position. A latch assembly may be mounted on the pantograph base and operable to move between a latch locked position and a latch unlocked position.
US09937798B2 Wrap around bus bar for vehicle power distribution device
A wrap around bus bar that provides battery power (also referred to as B+ power) to components within a power distribution device for a vehicle electrical system, such as a hybrid-type power distribution box (PDB). The power distribution device routes or distributes power throughout a vehicle electrical system and may include a lower cover, a wrap around bus bar, a relay block assembly, a module with a printed circuit board (PCB), an array of relays and fuses, and an upper cover. Battery power is provided from a vehicle battery and/or alternator to a terminal connection, from the terminal connection to the wrap around bus bar, and from the wrap around bus bar to the relay block assembly, the module and potentially other components within the power distribution device.
US09937797B2 Vehicle fingerprint bookmark
Provided in the present disclosure is a fingerprint bookmark system which may be implemented in a vehicle with one or more configurable interior settings. The fingerprint bookmark system may contain a scanner which may be configured to record a fingerprint from a vehicle occupant such that a fingerprint image showing the fingerprint and a duration data for the fingerprint image are recorded by the scanner. The system may contain one or more processors which may be configured to compare the duration data associated with the fingerprint image with a duration threshold. The one or more processors may be configured to initiate a search to obtain a bookmark for the fingerprint shown in the fingerprint image when the duration data is less than the duration threshold. The one or more processors may be further configured to create a new bookmark when the duration data exceeds the duration threshold.
US09937793B2 Three dimensional view interactive activation system to deploy information
An interactive activation system having a base with a display module that projects two or more icons. The display module is connected to the base. A case is connected to the base and covers the display output module. The case has one or more apertures that aligned with the display output module in a manner that allows the two or more icons to be projected through the one or more apertures. An output screen is connected to the case and has at least one reflective surface that is positioned relative to the one or more apertures of the case. This allows the two or more icons projected by the display output module to be reflected by the reflective surface of the output screen toward a viewing zone.
US09937792B2 Occupant alertness-based navigation
Systems and methods are disclosed for occupant alertness-based navigation. An example vehicle includes a camera and an occupant monitor. The example camera is affixed to a rear-view mirror of the vehicle to detect drowsiness events associated with a driver. The example occupant monitor is to, in response to detecting, with the camera, a first drowsiness event, provide feedback to a driver. Additionally, the example occupant monitor is to, in response to detecting a second drowsiness event after the first, select an accommodation in the geographic vicinity of the vehicle, and set a navigation system to navigate to the selected accommodation.
US09937790B2 Mounting assembly for vehicle shift mechanism
A mounting assembly for a vehicle shift mechanism is provided and includes a steering column having a stationary portion and a moveable portion. The mounting assembly also includes a column clamping structure of the stationary portion surrounding a portion of the moveable portion of the steering column. The mounting assembly further includes a shifter operatively coupled to the moveable portion of the steering column at a first coupling position located on a first side of the column clamping structure and at a second coupling position located on a second side of the column clamping structure. The mounting assembly yet further includes a stationary portion aperture defined by the stationary portion of the steering column, the stationary portion aperture extending from the second side of the column clamping structure in a longitudinal direction of the steering column, the second coupling position located within the stationary portion aperture.
US09937788B1 Fuel tank
A fuel tank has a welded member that is welded inside a fuel tank body. The welded member includes a welded face that is welded on at least one of a first tank face and a second tank face which faces the first tank face, of the fuel tank body, and wherein the welded face includes a facing side in a concave shape that faces a given point determined based on a displacement of distance between the first tank face and the second tank face when the fuel tank body receives an internal pressure.
US09937777B2 Belt molding
A belt molding includes: a molding body, which includes an inner wall, an outer wall, and a connection wall that connects an upper end of the inner wall and an upper end of the outer wall; a design lip, which is formed at the upper end of the inner wall of the molding body; and a design portion, wherein the design portion includes a first portion, which covers at least a part of the molding body, and a second portion, which covers at least a part of the design lip, and wherein a step is formed between the first portion and the second portion, such that a level of a surface of the first portion is different from a level of a surface of the second portion.
US09937776B2 Removable aerodynamic truck topper
Removable aerodynamic truck toppers. The truck toppers comprise a frame configured to surmount the top rails of a bed of pickup truck wherein the frame is covered with a fabric cover.
US09937775B2 Air nozzle
An air nozzle for discharging an air flow from an air supply duct of a heating, ventilation or air-conditioning system, in particular in a passenger compartment of a vehicle, composed of a nozzle body and of a receiving element which receives the nozzle body, wherein the receiving element is arranged on the air supply duct, and wherein the nozzle body and/or the receiving element are/is mounted so as to be pivotable about at least one degree of freedom, wherein in the interior of the nozzle body there is arranged a swirl insert which is arranged fixedly and which is connected rigidly to the nozzle body.
US09937773B2 Apparatus and method for controlling compressor
A compressor control apparatus may include a data detector detecting status data including at least one of vehicle speed, engine speed, accelerator pedal location value, and slope way measurement value; and controller that determines whether engine speed and accelerator pedal location value of the status data satisfy oscillation acceleration entering condition, if the vehicle speed exists in predetermined range and that sets basic operation rate of compressor according to the engine speed and the accelerator pedal location value, if engine speed and accelerator pedal location value of the status data satisfy oscillation acceleration entering condition and that generates final operation rate of the compressor using the basic operation rate, slope way constant according to the slope way measurement value, and air temperature compensation constant according to air temperature and that controls operation of the compressor based on the final operation rate.
US09937772B2 Heater
A heater, particularly for a motor vehicle, having at least one heating element for heating air and a control unit, which has a control circuit, arranged on a printed circuit board, for controlling the at least one heating element, whereby the at least one heating element has ribs and a contact strip, whereby a contact strip section is arranged on the circuit board of the control circuit and forms a connection between the at least one heating element and the control circuit.
US09937761B2 Railroad trailer chassis
A railroad trailer chassis comprising two or more road axles, two or more rail axles operable to be moved between first and second positions, and a work unit. The railroad trailer chassis is operable to be driven or towed in a road mode when the two or rail axles are in their respective first positions. The railroad trailer chassis is operable to be driven or towed in a rail mode when the two or more rail axles are in their respective second positions. The work unit is operable to perform one or more railroad maintenance or operation functions when driven in the rail mode.
US09937758B2 Pneumatic tire
A pneumatic tire 1 having a toroidal carcass 6 extending from a tread portion 2 through a sidewall portion 3 to a bead core 5 in a bead portion 4, is provided in the bead portion 4 with a bead reinforcing rubber layer 10 along an outer surface in the tire axial direction of the carcass 6. The bead reinforcing rubber layer 10 is formed from a band-like rubber strip 15 wound spirally circumferentially of the tire. In a tire meridian section including the tire rotational axis, each of the inner surface Si and the outer surface So in the tire axial direction of bead reinforcing rubber layer 10 has adjacent rubber strip 15's interfaces 16, and the number of the interfaces 16 on the inner surface Si is smaller than the number of the interfaces 16 in the outer surface So.
US09937755B2 Motorcycle tire
A motorcycle tire including a tire structure having a tread having outer surface curved in arc shape such that the outer surface is protruding toward radially outer side of the structure. The tread includes a center region and shoulder regions on sides of the center region, respectively, the center region is spanning 30% of a developed tread width with tire equator at the center of the center region, the tread has main grooves positioned at interval in tire circumferential direction and shoulder sub-grooves positioned in each shoulder region, each main groove is formed in V shape such that the V shape has a pair of inclined portions respectively extending from the tip in the center region toward the shoulder regions in tire rotation direction, and the sub-grooves are formed such that each sub-groove is extending in the circumferential direction and connected to one inclined portion without connecting adjacent main grooves.
US09937754B2 Tire for two-wheeled vehicles, comprising a tread having a circumferentially continuous groove
A tire for a motorized two-wheeled vehicle comprising a reinforcing structure of the carcass type, made up of reinforcing elements, anchored on each side of the tire to a bead the base of which is intended to be mounted on a rim seat, each bead being extended radially outward by a sidewall, the sidewalls radially toward the outside joining to a tread. At least the central part of the tread comprises at least one circumferentially continuous cut, the cut being made up, for at least 80% of its length of at least one incision and at most 20% of at least one part having a width greater than that of an incision and the apparent area of the at least one incision is greater than the apparent area of the at least one part having a width greater than that of an incision.
US09937753B2 Tire comprising a crown reinforcement
The invention relates to a tire comprising a crown reinforcement formed of at least two working crown layers of reinforcing elements the ends of which are radially uncoupled by a polymer compound. According to the invention, the reinforcing elements of at least one working crown layer are metal cords with saturated layers, at least one internal layer being sheathed with a layer consisting of a polymer composition such as a rubber composition and in each of the shoulders of the tire, at least the uncoupling polymer compound in contact with the ends of at least two working crown layers exhibits, in the sorption test, a gas content lower than 0.06 m3STP/m3ML.
US09937751B2 Positioning systems
A method and apparatus for positioning a manufacturing tool. A wheel assembly comprises a wheel plate and rollers. The wheel plate has a perimeter and an axis of rotation that is tiltable about a tilt axis. The rollers are arranged near the perimeter of the wheel plate, each of the rollers having an axis of rotation parallel to the tilt axis. An apparatus comprises an upper frame, a lower frame associated with the upper frame, a wedge slideably located between the upper frame and the lower frame, and a force applicator associated with the wedge.
US09937747B2 Elastomeric fastener system for wheel devices
A system. The system includes a wheel, a protective device and a fastener system. The fastener system is connected to the wheel and the protective device. The fastener system includes an elastomeric fastener configured to allow for controlled radial and rotational displacement of the protective device relative to the wheel in x and y directions.
US09937738B2 Adjustable inkjet printer for the labeling of goods
Inkjet printer for the labeling of goods having a print head having a cylindrically shaped housing. A latching lug, and a circumferentially extending groove are formed on the housing in a rear region thereof, in the vicinity of a rear face of the housing. Further, it has an annular collar having an inner wall adapted to the housing. On the one hand, the housing is capable of being fixed and, on the other hand, it is rotatable and axially movable, relative to the annular collar. The annular collar has a bore hole axially aligned with the groove, and a fixing projection located in the bore hole. Further, it has several latching recesses for the latching lug. When the latching lug is positioned in one of the latching recesses, the bore hole is located radially above the groove.
US09937736B2 Printing apparatus, paper supply apparatus, and paper supply method
A printer includes a first housing part, a second housing part, a printing part that prints on the first paper sheet and the second paper sheet, a conveying part that includes a holding part that is configured to hold the overlapping first paper sheet and the second paper sheet respectively pulled out from a first paper roll and a second paper roll, and conveys the first paper sheet out of the first paper sheet and the second paper sheet held by the holding part to the printing part, a first paper sheet sensor that detects the presence of the first paper sheet, and a controlling part that makes the conveying part convey the second paper sheet held by the holding part to the printing part when the first paper sheet sensor detects that there is no first paper sheet to be conveyed to the printing part.
US09937732B2 Medium transport apparatus
A medium transport apparatus includes a transport section configured to support a medium and transport the medium in a transport direction, and a wrinkle reducing section configured to come into contact with the medium to reduce the formation of wrinkles in the medium. The wrinkle reducing section can change surfaces to come into contact with the medium. The medium transport apparatus having such a structure enables to reduce the formation of wrinkles in the medium.
US09937730B2 Printer
A printer printing an image on a print medium based on print data including print dot data for each of print lines. The printer includes a print head including heating elements arranged along a direction of the print lines, and a controller finding the number of print dots on each print line and determining a first or second control mode as a control mode of the heating elements for printing each print line based on the found number of print dots. In the first control mode, the heating elements are divided into first groups including two or more adjacent heating elements and are heated at a different timing. In the second control mode, the heating elements are divided into second groups including two or more heating elements with at least two thereof spaced apart and are heated at a different timing.
US09937720B2 Liquid droplet ejecting apparatus
A printing device includes a heating section capable of heating paper P transported over a support platform, a head unit that is disposed at a position facing the support platform with a gap therebetween, and that is capable of rotating about a rotation shaft extending along width direction X, and a head cooling unit that is capable of cooling the head unit. The head unit is provided with a first head that includes a nozzle capable of ejecting ink, a second head that includes a nozzle capable of ejecting ink, and a third head that includes a nozzle capable of ejecting ink, with the heads provided around a rotation direction of the head unit with gaps between one another. When one head out of the respective heads faces the paper P, another head out of the respective heads can be made to face the head cooling unit.
US09937719B2 Ink-jet head
There is provided an ink-jet head including: first and second head chips each formed with two first nozzle arrays extending in a first direction, each of the first nozzle arrays including first nozzles corresponding to a first ink, second nozzles corresponding to a second ink, and third nozzles corresponding to a third ink; third and fourth head chips each formed with two third nozzle arrays extending in the first direction, each of the third nozzle arrays including fourth nozzles corresponding to the fourth ink. The first head chip to the fourth head chip are arranged in parallel in a second direction orthogonal to the first direction.
US09937718B2 Ink jet head and ink jet recording apparatus
According to one embodiment in an ink jet head, the common electrodes for all the actuators, without overlapping with the first wiring pattern formed by individual electrodes, are connected to a second wiring pattern that passes between the outer peripheral portion of piezoelectric bodies, and a third wiring pattern that extends in a direction different from a direction of the second wiring pattern. The first wiring pattern and the third wiring pattern are electrically insulated at intersections thereof.
US09937712B2 Liquid ejecting apparatus and head unit
A liquid ejecting apparatus which includes a modulation circuit which generates a modulated signal obtained by performing pulse modulation with respect to a source signal as a source of a driving signal; a boosting circuit which outputs a voltage boosted by at least a first capacitor; a pair of transistors which generates an amplified-modulated signal based on the modulated signal; a low pass filter which generates a driving signal by smoothing the amplified-modulated signal; a voltage generating circuit which outputs an offset voltage from an output terminal; and a second capacitor which is electrically connected to the output terminal, in which at least the boosting circuit and the voltage generating circuit are integrated in an integrated circuit, and a distance between the first capacitor and the integrated circuit is shorter than a distance between the second capacitor and the integrated circuit.
US09937702B1 Method and apparatus for calibrating a three dimensional (3D) printer
Embodiments include an apparatus for fabricating a three-dimensional object from a digital representation of the object stored in a computer readable media, the apparatus comprising: a component having a surface on which the object is to be fabricated, wherein information is embedded within the component; a sensor configured to sense the information embedded within the component; a module configured to, based on the sensor sensing the information embedded within the component, determine one or both of (i) a characteristic of the component and (ii) a configuration parameter of the apparatus; and a print mechanism disposed above the surface of the component, wherein the print mechanism is configured to, based on the determined one or both of (i) the characteristic of the component and (ii) the configuration parameter of the apparatus, fabricate the object on the surface of the component.
US09937698B2 Peeling method and light-emitting device
The yield of a peeling process is improved. A first step of forming a peeling layer to a thickness of greater than or equal to 0.1 nm and less than 10 nm over a substrate; a second step of forming, on the peeling layer, a layer to be peeled including a first layer in contact with the peeling layer; a third step of separating parts of the peeling layer and parts of the first layer to form a peeling trigger; and a fourth step of separating the peeling layer and the layer to be peeled are performed. The use of the thin peeling layer can improve the yield of a peeling process regardless of the structure of the layer to be peeled.
US09937695B2 Bonding of substrates induced by ionizing radiation
A reactive polymer composition is provided, containing a (co)polymer that forms one or more reactive moities, either directly or indirectly, upon application of an ionizing radiation; and a multifunctional curing coagent, along with systems and methods for bonding substrates to one another using such a composition.
US09937692B2 Method for the manufacture of reinforced materials and material that can be obtained from this method
A method for the manufacture of reinforced core composites, comprises: inserting of a pin into a foamed core material or a filled honeycomb-shaped core material, wherein the pin and the core material contain a thermoplastic polymer, or a mixture of thermoplastic polymers; the pin is heated such that as the pin is inserted the core material softens or melts at the point of insertion; and/or the core material is heated at the point of insertion such that the core material softens or melts.
US09937690B2 Two-stage application device for installing screen protectors and kit comprising the application device
A two-stage application device is disclosed for installing a screen protector on a display screen of a screen-mounted device. The application device includes a base, a first actuating lever, and a second actuating lever. The base includes an accommodation and a support, wherein the support defines first grooves and second grooves. The first actuating lever has first controlled pivot portions guided and limited by the first grooves, a first pressing portion, a first arm, and a body with a positioning protrusion. The second actuating lever has second controlled pivot portions guided and limited by the second grooves, a second pressing portion, a second arm, and a body. A kit is also disclosed for protecting a display screen of a screen-mounted device, which includes a two-stage application device, and at least one screen protector including a protective film with at least one adhesive layer, and a backing sheet.
US09937689B2 Polarizing film, method for manufacture thereof, optical film, and image display device
In a method for manufacturing a polarizing film comprising a polarizer, a first transparent protective film provided on one surface of the polarizer with an adhesive layer interposed therebetween, and a second transparent protective film provided on another surface of the polarizer with an adhesive layer interposed therebetween, the adhesive layers are obtained by first using active energy rays to carry out irradiation by way of the first transparent protective film and then using the active energy rays to carry out irradiation by way of the second transparent protective film to cure the active energy ray-curable adhesive composition.
US09937688B2 Stretched laminated film for use in piezoelectric polymer material, and manufacturing method thereof
The object of the present invention is to provide a laminated film made of polylactic acids which is not prone to delamination while having excellent piezoelectric properties and a manufacturing method thereof. That is, the present invention is obtained by the stretched laminated film manufactured by a co-extrusion process for use in piezoelectric polymer materials, containing a layer (A) which has poly-L-lactic acid as the primary component and contains an impact modifier in the range of 0.1 to 10 mass % and a layer (B) which has poly-D-lactic acid as the primary component and contains an impact modifier in the range of 0.1 to 10 mass %.
US09937685B2 Industrial products engineered from processed bamboo or vegetable cane
A natural fiber-based, engineered beam assembly comprising opposing top and bottom surfaces, opposing first and second side surfaces and a longitudinal axis. Loads applied to the beam assembly are normal to the top surface. Substantially parallel layers of flattened bamboo or vegetable cane culms are stacked and laminated together. Each layer is formed by at least one culm, and each culm has fiber bundles extending substantially parallel to the longitudinal axis and are impregnated with a binder. The density of the fiber bundles in the culm decreases across the culm's thickness from the exterior surface to the interior surface. At least a plurality of the culms have a common orientation, wherein the exterior surfaces face toward a same one of the top, bottom, first or second side surfaces.
US09937683B2 Composite sheet, production method thereof and electronic apparatus using the same
A composite sheet includes a graphite layer, a heat insulation layer including a fiber and a heat insulation material and a fiber layer located between the graphite layer and the heat insulation layer, wherein the fiber layer comprises the fiber. An electronic apparatus includes an electronic component that involves heat generation, a housing and the composite sheet, wherein the composite sheet is placed between the electronic component and the housing.
US09937669B2 Three-dimensional printed part removal using a bimetallic platen
A three-dimensional object printer has a platen that is configured to facilitate the release of objects formed on the platen. The platen includes a first layer and second layer, the first layer having a coefficient of thermal expansion that is different than a coefficient of thermal expansion of the second layer. A controller in the printer is configured to operate at least one ejector in an ejector head to form a three-dimensional object on the surface of the platen with reference to digital image data and, upon completion of the object, to operate a temperature control device operatively connected to the platen to bend the platen by changing the temperature of the platen and releasing a three-dimensional object from the platen.
US09937664B2 Method for producing a three-dimensional structure
A method for producing a three-dimensional structure (10) in a lithographic material (24) that can be polymerized and thus solidified using energy input methods, wherein initially a shell wall (16) of the three-dimensional structure (10) to be produced is polymerized so as to form a polymerized shell wall (16) such that a volume (28) of unpolymerized lithographic material is enclosed using a first, spatially resolving energy input method, wherein the lithographic material (24) surrounding the polymerized shell wall (16) is removed in an intermediate development step, wherein subsequently the volume (28) enclosed by the shell wall (16) is polymerized using a second energy input method.
US09937661B2 Storage electric sealer
A storage electric sealer comprises a casing, a sealing module, a spring switch, a support cover, a press bar, and a sliding plate. The casing and the sealing module are arranged on the casing. The support cover includes at least two containing grooves. The press bar provided with a sliding chute is pivotally connected with the pivoting holder of the casing. The sliding plate is provided with a heat insulation block and at least a stopper, both lateral side of the sliding plate being connected with the sliding chute of the press bar in a sliding manner. Wherein, the sliding plate is located at a closed position in storage state, so that the stopper is accommodated in the containing groove of the support cover. As such, the storage electric sealer can be transformed into a storage state by a modified sliding mechanism to reduce the volume and damage rate effectively.
US09937654B2 Molding device of inbuilt component fixing section of fuel tank
A molding device of an inbuilt component fixing section of a fuel tank includes: a projection member that projects out at a placement face onto which a resin sheet that will form a tank configuration member is disposed in a molten state, and that molds a hollow bulge section in the resin sheet; an elastic body that covers the projection member, and that expands and applies pressure to the bulge section from the inside due to a non-compressible fluid being supplied into a sealed space formed between the elastic body and the projection member; a fluid supply device that supplies the fluid into the sealed space in a state in which the bulge section has penetrated through a fixing hole provided in an inbuilt component; and a fixing member that fixes a location of the elastic body corresponding to a leading end portion to the leading end portion.
US09937652B2 Polymeric material for container
A formulation for producing a polymeric material including high-density polyethylene, a chemical blowing agent, and other optional components is described.
US09937651B2 Resin delivery apparatus and method with plural air flow limiters
Apparatus has a vacuum pump for conveying granular plastic resin material from a supply to receivers retaining and dispensing the resin when needed by a process machine with a flow limiter connected to the suction head of the vacuum pump, and a second flow limiter controlling and limiting to a maximum value vacuum flow through a conduit carrying auxiliary additives to the receivers.
US09937650B2 Operating unit for an injection molding machine
An operating unit includes a touch-sensitive display screen for displaying an operating program, a control or regulating unit for communicating operating signals to injection molding machine elements, and the operating program is stored in the control or regulating unit, and at least one operating button, upon the actuation of which the control or regulating unit triggers an action of an injection molding machine element. The operating program has a hierarchical system architecture with at least one upper installation-specific level and an upper task-specific level. A selection can be made between different installation regions in the installation-specific central level, between different task regions in the task-specific central level, and a plurality of sublevels. Process-relevant program pages associated only with the selected installation region or only with the selected task region can be displayed in each selected sublevel.
US09937647B2 Co-injection with continuous injection molding
A carousel-like continuous co-injection molding system includes an arrangement of upper and lower inclined feed channels. Each of the feed channels has a valve therein positioned upstream of an inlet to an associated mold cavity. The valve is controllable so that adjustments may be made in real time to achieve or maintain delivery of molten polymeric material to the mold cavity at constant pressure.
US09937643B2 Concrete forming systems and methods
Systems and methods for constructing concrete foundations are provided which allow for rapid and high-precision placement and alignment of anchor bolts across large distances. A frame system is constructed outside of an excavation and then suspended, using supports, over an excavation. The frame system can include a frame having one or more templates for anchor bolts, a form suspended from the frame, and a mat and cage assembly tied to the frame. The frame system can be aligned in proper position and the anchor bolts placed in the frame system before the concrete is placed. In this way, the anchor bolts can be cast in place as the footing is placed.
US09937642B2 Construction material composition and method of forming construction materials utilizing rice hulls
Provided are a structure and a method of forming a structure that includes a core made, at least in part, of a rice hull composition. The rice hull composition including a combination of separate, unground rice hulls; ground rice hulls; and a rice hull powder, that each have a different particle size. A caustic-free polyurethane resin binds the separated unground rice hulls, the ground rice hulls and the rice hull powder together.
US09937641B1 Quick release sleeve chill roll
The present invention is a method and apparatus for quick and easy rubber sleeve exchanges on chill rolls, such as are used in film extrusion processes. The apparatus includes chill roll or mandrel, a rubber sleeve covering the exterior face of the mandrel, an automated cantilever system, and an air booster. The rubber sleeve is easily removed by tilting the mandrel and inserting a layer of air between the rubber sleeve and the mandrel, thereby allowing the sleeve to slip off the mandrel and allowing for a new rubber sleeve to be placed onto the mandrel.
US09937639B2 Powder heating assembly and heating module of rapid prototyping apparatus
A powder heating assembly of a rapid prototyping apparatus includes a powder feeder and a heating module. The powder feeder includes an accommodation space and a powder falling port in communication with the accommodation space. The heating module is disposed under the powder feeder, and includes a thermally conductive cap and a heat conduction structure. The powder falling port is capped by the thermally conductive cap. The thermally conductive cap includes a powder exhaust port. The powder exhaust port is in communication with the powder falling port. The heat conduction structure is arranged between the accommodation space of the powder feeder and the thermally conductive cap and includes a heater. The heat generated by the heater is transferred to the construction powder within the powder feeder to preheat the construction powder, remove the moisture contained in the construction powder and dry the construction powder.
US09937637B1 Mobile mixing apparatus with adjustable mixing paddles
A mobile mixing apparatus for ensuring optimal mixing of a material includes a support member which is mobile on a support surface. A mixing drum is carried by the support member. The mixing drum has a base drum end, a side drum wall extending from the base drum end, an open drum end opposite the base drum end, a drum interior extending between the base drum end and the open drum end, a central inner surface and a base inner surface on the base drum end and a side inner surface on the side drum wall and facing the drum interior. A paddle assembly is disposed for rotation in the drum interior of the mixing drum. The paddle assembly includes a plurality of paddles engaging the central inner surface, the base inner surface and the side inner surface, respectively, of the mixing drum. At least one motor drivingly engages the paddle assembly for rotation in the drum interior of the mixing drum.
US09937635B2 Method of constructing a wind tower foundation
A fatigue resistant gravity based spread footing under heavy multi-axial cyclical loading of a wind tower. The foundation having a central vertical pedestal, a substantially horizontal continuous bottom support slab, a plurality of radial reinforcing ribs extending radially outward from the pedestal. The pedestal, ribs and slab forming a continuous monolithic structure. The foundation having a three-dimensional network of post-tensioning elements that keep the structural elements under heavy multi-axial post compression with a specific eccentricity intended to reduce stress amplitudes and deflections and allows the foundation to have a desirable combination of high stiffness and superior fatigue resistance. The foundation design reduces the weight and volume of materials used, reduces cost, and improves heat dissipation conditions during construction by having a small ratio of concrete mass to surface area thus eliminating the risk of thermal cracking due to heat of hydration.
US09937634B2 Compositions and methods for treating cellulose-based materials with micronized additives
A composition for treating cellulosic materials is provided. The composition comprises a dispersion of micronized additives. The dispersion comprises additive particles with diameters in the range of 0.001 to 25 microns. Also provided is a method for the application of the additive-containing composition to wood, as well as wood products which have been treated with the composition.
US09937628B2 Safety device for a mechanical motion device
A safety device for a mechanical motion device and a method for protecting a person or object in the vicinity of a mechanical motion device are described herein. The safety device may include: a shroud; a coupling mechanism; and a detection device. The coupling mechanism joins the shroud in a displaceable manner to a mechanical motion device. The detection device is configured for communication with the safety control system of a mechanical motion device. The detection device is capable of detecting misalignment of the shroud from its initial aligned position and/or a collision between the shroud and a person or object. The detection device may send a signal to the safety control system of the mechanical motion device to at least slow the movement of the mechanical motion device before the mechanical motion device reaches the location of the collision of the shroud with an object or person.
US09937627B2 Manufacturing vacuum tool with selective activation of pickup zones
The present invention provides systems, methods, and apparatus for a vacuum tool having a switchable plate, such that a common vacuum tool may be adapted with different plates. A switchable plate may form the entirety of the vacuum tool's material contacting surface or a switchable plate may form a portion of the material contacting surface. The vacuum tool is effective for picking and placing one or more manufacturing parts utilizing a vacuum force.
US09937625B2 Self-locating robots
A method and apparatus for a robot self-locating on a movement surface. The method may comprise moving a first robot across the movement surface and relative to a workpiece, in which the movement surface faces the workpiece. The method may also form sensor data using a first number of sensors on the first robot as the first robot moves across the movement surface, in which the sensor data represents identifying characteristics of a portion of the movement surface. The method may also determine a location of the first robot on the movement surface using the sensor data. The method may further determine a location of a functional component of the first robot relative to the workpiece using the location of the first robot on the movement surface.
US09937624B2 Mechanism-parameter-calibration method for robotic arm system
A mechanism-parametric-calibration method for a robotic arm system is provided. The method includes controlling the robotic arm to perform a plurality of actions so that one end of the robotic arm moves toward corresponding predictive positioning-points; determining a predictive relative-displacement between each two of the predictive positioning-points; after the robotic arm performs each of the actions, sensing three-dimensional positioning information of the end of the robotic arm; determining, according to the three-dimensional positioning information, a measured relative-displacement moved by the end of the robotic arm when the robotic arm performs each two of the actions; deriving an equation corresponding to the robotic arm from the predictive relative-displacements and the measured relative-displacements; and utilizing a feasible algorithm to find the solution of the equation.
US09937623B2 Methods and systems for kitting parts for manufacturing processes
Methods comprise (a) sequentially transferring, from a part supply structure to a part staging structure, a first predetermined selection of parts; (b) sequentially transferring, from the part staging structure to a first manufacturing kit holder, the first predetermined selection of parts to define a first kitted holder; (c) concurrently with (b), sequentially transferring, from the part supply structure to the part staging structure, a second predetermined selection of parts; and (d) subsequent to (b), sequentially transferring, from the part staging structure to a second manufacturing kit holder, the second predetermined selection of parts to define a second kitted holder. Systems comprise a part supply structure; a part staging structure; a first robotic transfer device; a plurality of manufacturing kit holders; a second robotic transfer device; and a holder positioning structure.
US09937622B2 Method for robot-supported stacking of objects
The invention relates to a method for positioning, in particular for palletizing, objects. The method is carried out using a manipulator having an additional actuator which is arranged between the manipulator and the object to be positioned. According to one example of the invention, the method comprises the gripping of the object and the moving of the object, using the manipulator, at a start position in the proximity of a storage surface on which the object is to be positioned and deposited. The method furthermore comprises the moving of the object using the manipulator to the storage surface, wherein the actuator is actuated such that the actuating force compensates for the weight of the object, or wherein the actuator force is regulated such that an adjustable, minimal net actuator force acts on an end stop of the actuator (which can be zero in the limiting case). Furthermore, the excursion of the actuator is monitored and a change to the excursion is detected. The movement of the manipulator is stopped upon detecting a change to the excursion of the actuator, whereupon the object can be released.
US09937619B2 Control method for a robot
The invention relates to a control method for a robot (1) having a plurality of movable robot axes (2, 4, 6), in particular for a painting robot (1) or a manipulating robot, comprising the following steps: (a) predetermining a robot path by means of a plurality of path points through which a reference point of the robot (1) is intended to travel; (b) controlling drive motors of the individual robot axes (2, 4, 6) according to the predetermined robot path, such that the reference point of the robot (1) travels through the predetermined robot path; (c) precalculating the mechanical loading (My1, Mx1, Fx1, Fy1, Fz1, Fx2, Fy2, Fz2, Mx2, My2, Mz2) that occurs within at least one of the robot axes (2, 4, 6) between two joints when travelling through the robot path ahead; and also (d) adjusting the control of the drive motors of the robot axes (2, 4, 6) on the basis of the precalculated mechanical loading (My1, Mx1, Fx1, Fy1, Fz1, Fx2, Fy2, Fz2, Mx2, My2, Mz2), such that a mechanical overload is avoided.
US09937618B2 Hybrid hydraulic and electrically actuated mobile robot
Example embodiments may relate to a robotic system that includes a hydraulic actuator and an electric actuator both coupled to a joint of the robotic system. Operation of the actuators may be based on various factors such as based on desired joint parameters. For instance, such desired joint parameters may include a desired output torque/force of the joint, a desired output velocity of the joint, a desired acceleration of the joint, and/or a desired joint angle, among other possibilities. Given a model of power consumption as well as a model of the actuators, the robotic system may determine operating parameters such as hydraulic and electric operating parameters as well as power system parameters, among others. The robotic system may then control operation of the actuators, using the determined operating parameters, to obtain the desired joint parameters such that power dissipation in the system is minimized (i.e., maximizing actuation efficiency).
US09937613B2 Striker member, and a drilling machine comprising a striker member
A circular cylindrical striker member 2 for a drilling machine adapted to transfer kinetic energy to an impulse receiving member 4. The striker member has a diameter dmax, and includes a side surface 12 and an impulse surface (6). The striker member is adapted to transfer the kinetic energy to the impulse receiving member by a ring shaped active surface of the impulse surface, wherein the ring shaped active surface is concentric with regard to the cross section of the striker member, has a diameter da, where da
US09937610B2 Accessories for fastener driving apparatus
Accessories for a fastener driving apparatus are disclosed, which accessories may be removably attached to a fastener driving apparatus. An extension accessory increases the length of reach of a fastener driving apparatus by including an extension rod and further improves accuracy with regard to driving a fastener into a substrate via a fastener retention mechanism. A chisel accessory provides added versatility for a fastener driving apparatus by including a chisel tool function in addition to a fastener driving function. A fastener setting accessory improves fastener driving ease and accuracy by driving fasteners presently in a substrate to a specific depth. The accessories are specifically designed to transmit an uninterrupted force from the fastener driving apparatus to a fastener or chisel for driving a fastener into or otherwise impacting or striking a substrate.
US09937605B2 Illumination structure for pliers
An illumination structure for pliers contains: a first part, a second part, and an illumination device. The first part includes a first clamping jaw, a first handle, and a first rotatable connecting portion between the first clamping jaw and the first handle. The second part includes a second clamping jaw, a second handle, and a second rotatable connecting portion between the second clamping jaw and the second handle, wherein the first rotatable connecting portion of the first part and the second rotatable connecting portion of the second part are rotatably connected together. The first rotatable connecting portion has an accommodation groove configured to house the illumination device, and the accommodation groove has a first opening communicating with the first clamping jaw and the second clamping jaw and has a second opening communicating with the first handle. The illumination device includes a light emitting element and a control button.
US09937604B2 Abrasive article and method of making same
An abrasive article has an abrasive portion with a bond and abrasive particles. A core is mounted to the abrasive portion. The core may include a plurality of segments that are interconnected to form the core. The abrasive article may include forming a plurality of core segments; assembling the core segments into a core; and then mounting the core to the abrasive portion to form the abrasive article. Forming an abrasive article may include mixing a phenolic resin, fillers and abrasive particles to form an abrasive matrix; injecting the abrasive matrix directly into a mold, such that the abrasive matrix is injection molded into a final wheel geometry; at least partially curing the abrasive matrix while it is inside the mold; and then removing the abrasive article from the mold.
US09937598B2 Cover for cutting tool, holder for cutting, and cutting device
A cutting tool cover set to a cutting tool which includes a hollow shaft body and at least one insert attached to an end face of the shaft body and cuts by bringing the insert into contact with a work while rotating the shaft body. The cutting tool cover includes: a body portion fixed to a top end portion of the shaft body; and an extension portion extended outward from the circumferential edge of the body portion in the entire circumference of the top end portion of the body portion to cover the surface of the work.
US09937593B2 Method, apparatus and plant for cutting and fitting a cap onto the opposite cut ends of a pipe
Method for fitting caps by means of an automatic apparatus onto at least one end of a pipe, fed in a longitudinal direction by a pipe-feeding machine and directed to a machine for bundling the pipe, wherein said apparatus being movable alternately in both senses of the longitudinal direction between two opposite end-of-travel ends, i.e. rear end facing the feeding machine, and front end opposite to the rear end.
US09937590B2 Laser processing machine
Laser processing machines, such as laser cutting machine (LM), including a work table receiving workpiece (W), and work arm (1) with a laser cutting head (2). Laser cutting head (2) includes nozzle receiving device (7) and nozzle (D). Via nozzle (D) laser beam (11) may be directed onto work piece (W). Machine (LM) includes main drives moving work arm (1) and/or the laser cutting head (2) on X-Y-Z axes to process work piece (W), as well as an alignment unit to adjust laser beam (11). An adjusting station (3) includes receiving unit (31) fixing nozzle (D) and/or the nozzle receiving device (7) during centering of nozzle (D). The alignment unit has head element (5B) in laser cutting head (2). Head element (5B) receives nozzle (D) and/or the nozzle receiving device (7) and is slidable in X-Y directions, via the main drives. Head element (5B) may be fixed in a selected position, within the laser cutting head (2), via clamping device (12) releasable during nozzle centering at adjusting station (3).
US09937587B2 Process for friction stir welding dissimilar metals and workpiece assemblies formed thereby
In a process for friction stir welding together pieces of dissimilar material, a first piece of a second metal is overlaid onto a first piece of a first metal that is dissimilar from the second metal such that at least a portion of the first piece of second metal overlaps a portion of the first piece of first metal. The first piece of second metal has a plurality of holes therein and the holes are disposed in overlapping relationship with the portion of the first piece of first metal. Each of the holes is filled with a plug formed from the first metal. The first piece of first metal is friction stir welded to the first piece of second metal at each of the plug locations.
US09937585B2 Multi-functional manufacturing tool
Aspects relate to systems, methods, and apparatus for a manufacturing tool. The manufacturing tool is comprised of a vacuum tool and an ultrasonic welder as a unified manufacturing tool. The manufacturing tool may be used to pick and position a manufacturing part that is then welded with the associated ultrasonic welder.
US09937584B2 Electron-beam-supported production of electrical components
A method for producing an electrical component is provided. The method includes steps of providing a continuous strip material and separating a section from the continuous strip material using an electron beam.
US09937582B2 Resistance welding device and resistance welding method
A resistance welding device is provided with a moving distance measuring section for measuring distances between conductors to be joined before and after joining and evaluating joining quality based on the distances, and a projection including a base and a projecting surface is provided to the conductor to be connected in order to easily secure a distance between the conductors after the joining.
US09937573B2 Power tool with detection system
A power tool includes a swing arm movable along a swing arm path, an actuating assembly configured to transfer a force to the swing arm, a control system configured to control the actuating assembly to transfer a force to the swing arm, and a detection system configured to detect the operability of the actuating assembly.
US09937568B2 Router
A router includes a housing and a motor assembly disposed within the housing. The motor assembly includes a driven shaft having a cavity on a first end of the driven shaft. The router includes a collet that is configured to mate into the cavity of the driven shaft with the collet being configured to grip a shank of a router bit. The router includes a gear mechanism that is configured to couple and decouple from a second end of the driven shaft such that a rotation of the gear mechanism when the gear mechanism is coupled to the second end of the driven shaft causes at least one of tightening and loosening of the collet.
US09937566B2 Spirally-fed drilling and milling cutter
A spirally-fed drilling and milling cutter to be driven spirally in order to drill and mill includes a shank, a groove at one of a plurality of offset positions at one end of the shank, a blade at a bottom side of the groove, and a spiral flute on the periphery of the main body of the shank, wherein the spiral flute has a flute end connected with the groove. When the cutter is rotated at high speed and in high torsion, drilling/milling chips are pushed upward, along with a cutting liquid, through the spiral flute out of a hole being made. Thus, the heat generated by the cutting action is reduced, and the chips are efficiently discharged, allowing the cutting edges to stay sharp and the cutter to make deep holes.
US09937561B2 Fly-cutting head, system and method, and tooling and sheeting produced therewith
A fly-cutting system is disclosed, and in particular one that comprises a dynamically-controllable actuator for controlling the position, orientation, or both position and orientation of a cutting element carried by a fly-cutting head. In certain embodiments, the actuator can adjust the position or orientation of a cutting element, or both, hundreds or thousands of times per second, enabling precise control over the shape of features formed by the cutting element in a surface of a workpiece.
US09937558B2 Fe-based sintered alloy and manufacturing method thereof
An Fe-based sintered alloy, essentially consists of, in percentage by mass, Mn: 0.5 to 2.0, Mo: 0.3 to 1.6, Cu: 0.4 to 1.5, C: 0.4 to 0.7 and the balance of Fe plus unavoidable impurities; and has a metallic structure made of 5 to 70% of martensite phase relative to a base material except pore and 25 to 90% of bainite phase relative to the base material except the pore.
US09937553B2 Liquid cooled die casting mold with heat sinks
A low pressure aluminum casting apparatus includes a pair of steel dies each presenting a molding surface and a heat transfer surface. Copper heat sink blocks are disposed on the heat transfer surfaces to remove heat from the steel dies. Steel contact plates and steel spacer plates can be disposed between the heat sink blocks and the steel dies to optimize cooling. In addition, a portion of each contact plate can be spaced from the steel die to reduce cooling. The steel dies include conventional cooling passages for conveying cooling fluid, and the heat sink blocks, contact plates, and spacer plates also include cooling channels for conveying cooling fluid.
US09937552B2 Rollover machine with safety braking mechanism
A cylindrical drum is driven for rotation about its axis by a drive mechanism. A braking mechanism selectively applies braking forces to the drum to impede or brake its rotational movement. A first movement sensor senses movement of the drive mechanism while a second movement sensor senses movement of the drum. An electronic comparator circuit compares these sensed movements and generates a control signal when the drive mechanism movement and drum movement are not in synchronism. In response to such loss of synchronism, a control mechanism causes the braking mechanism to apply braking forces.
US09937548B2 Joining apparatus and method
A joint is produced in at least two overlapping workpieces using a joining tool including a punch reciprocally disposed in a cylinder. The workpieces are disposed between the tool and a die. The tool applies a compressive force to deform the workpieces into a joint at a joining area between the tool and die. Continuous ultrasonic energy is applied to at least one of the workpieces in the joining area for at least part of the time during production of the joint to increase the ductility of at least one of the workpieces in the joining area. This induces an acousto-plastic effect in the material being formed which temporarily reduces its strength so as to exhibit increased ductility. The joining method may be used in self-piercing riveting and clinching techniques and enables viable joints to be formed in high strength materials or thick sheets of material.
US09937545B1 Mandrel support device for tube bending machine
A mandrel support device includes a mandrel sleeve positionable on a mandrel to form a reservoir in fluid communication with a mandrel passage, and with. The sleeve may include a bore configured to receive a portion of the mandrel, a lubrication channel formed on the sleeve exterior, and a lubrication passage extending between the channel and the bore to permit fluid communication therebetween. A mandrel base may define a socket for interchangeably receiving the sleeve, and a lubrication bore may extend from the socket to the base to align with the lubrication channel when the sleeve is received in the socket. A fluid fitting mounted on the base in fluid communication with the lubrication bore and the lubrication channel of the sleeve such that fluid moving through the fluid fitting enters the bore, the channel and passage to reach the reservoir and mandrel passage at any rotational position of the sleeve with respect to the base.
US09937543B2 Device for winding a strip material into a coil
The invention relates to a device for winding a strip material into a coil. The device comprises a winding mandrel (1) having a shaft element (2) and radially movable segments (16) mounted on the shaft element for winding and unwinding the strip material. The device further comprises an actuating drive (26) for spreading or collapsing the segments. The device also has a rotary drive (5) for rotationally driving the winding mandrel. To achieve a simpler and more economical design, a displacement device (60) is provided for axially displacing the actuating drive (26) together with the winding mandrel (1).
US09937537B2 Groundwater remediation systems, devices, and methods
A liquid treatment system includes: a filter casing including a structural wall, a first screen formed though the structural wall, and a second screen formed though the structural wall; and a liquid treatment cartridge configured for placement in the filter casing between the first and second screens. The liquid treatment cartridge includes a cartridge casing having an upper end and a lower end, and an inflatable seal surrounding the cartridge casing at an intermediary position between the upper end and lower end. A method of servicing a groundwater treatment installation includes: vertically displacing a liquid treatment cartridge within a filter casing having a structural wall, a first screen formed though the structural wall, and a second screen formed though the structural wall.
US09937534B2 Poultry feed distribution system with feeding devices having rotatable attachment parts with drop tubes hingedly connected thereto
A poultry feed distribution system includes a feed storage, a conveyor line and feeding devices. Each feeding device has an attachment part that is rotatable around the line. The attachment part has a drop tube of the device hingedly connected thereto. The attachment part together with the hinge connection to the drop tube is rotatable around the line between a feeding and a cleaning position, with an inlet of the drop tube getting distanced from the line when the attachment part together with the hinge connection to the drop tube is rotated from the feeding to the cleaning position.
US09937533B2 Panel polishing device and panel cleaning equipment
Disclosed is a panel polishing device, comprising a polishing belt movable along a predefined direction and a spray head arranged above the belt. The spray head has a main body and a plurality of through-holes penetrating the main body in its thickness direction. Through-holes have outlets facing the belt and are arranged along a length direction of the spray head. The length direction of the spray head conforms to a movement direction of the belt. At least the through-holes on both sides of the main body are oblique outwardly with respect to the remaining through-holes. Also, the disclosure provides a panel cleaning equipment including the panel polishing device. In the device according to the disclosure, pressure of bi-component fluid is more widely applied onto belt and a larger belt is contacted with the panel, such that the panel is thoroughly cleaned without polishing blind regions on both sides thereof.
US09937531B2 Method and system for delivery of goods
The present publication discloses a method and system for delivering goods from main system (S1) via subsystem (S2) to an end address (D1-Dn) of the customer (3). According to the invention the end address (D1-Dn) of the customer (3) is enquired (4) from the customer via telecommunications network by a multiple choice enquiry (4), the end address (D1-Dn) selected by the customer is received (5) and the goods are delivered to the selected end address (D1-Dn).
US09937530B2 Seal with support member
This disclosure is generally drawn to systems, devices, apparatus, and/or methods related to sealing mechanisms for vibratory separators. Specifically, the disclosed systems, devices, apparatus, and/or methods relate to seals having support(s) for improved installation in and/or removal from a vibratory separator. In some examples, an apparatus may include a seal and a support member. The seal may have two opposing side members and an end member coupled to and extending between the two opposing side members. The support member, which is at least partially rigid, may be coupled to the end member of the seal. In some examples, the support member may be integrated with or removably coupled to the seal.
US09937527B2 Methods for coating pipe
A method for producing a flexible tubular member having a cross-linked coating includes oxidizing an outer surface of a flexible tubular substrate, disposing a first radiation curable pre-polymer formulation on the oxidized outer surface, exposing the first radiation curable pre-polymer formulation to radiation to produce a first cross-linked coating layer, disposing a second radiation curable pre-polymer formulation on the first cross-linked coating layer, and exposing the second radiation curable pre-polymer formulation to radiation to produce a second cross-linked coating layer. The substrate includes a cross-linked polymer.
US09937525B2 Method of making polyester film with a reduced iridescent primer layer
This invention relates to a highly optically clear, composite film having a predominantly thermoplastic polyester base layer and a primer layer of a polyester and polyurethane blend composition. The base layer preferably has an A/B/C layered structure with a substantially particle-free core layer B of polyester and outer layers A and C of polyester containing nonpolyester, organic and/or inorganic particles. The primer layer is preferably applied to the base layer from solution that is organic solvent-free and is crosslinked using a carbodiimide crosslinking agent. The primer layer and base layer composite can be laminated with a protective layer of primarily acrylic polymer for a solar control film. Various layers of the composite and solar control films can contain effective amounts of functional additives, such as UV light blockers. Polyurethane in the primer, especially in combination with crosslinking by the carbodiimide, provides the acrylic coated polyester base solar control film with notably reduced iridescence and durable adhesion between polyester and acrylic layers in moist and warm service conditions.
US09937522B2 Discrete deposition of particles
A particle can be discretely ejected from a orifice.
US09937521B2 Method for spraying chemical solution
[Problem] To provide a method for spraying a chemical solution that makes it possible to uniformly apply a chemical solution onto a moving body and that exhibits excellent spraying efficiency.[Solution] The present invention is directed to a method for spraying a chemical solution in which, in a dry part D of a paper-making machine, a chemical solution is continuously sprayed onto a moving body that guides wet paper X, while a nozzle device S is reciprocating in directions orthogonal to a moving direction of the moving body with the moving body in motion, wherein: the moving body is a cylindrical dryer roller D1 or an endless canvas K1; and a travel distance H that the nozzle device S moves during a single rotation of the moving body and a width W of a sprayed area that is formed on the moving body by the nozzle device S satisfy the relationship represented by the following expression: 0.5≤H/W≤20.
US09937518B2 Application nozzle
An application nozzle for an application system for gel-like or pasty compositions. The application nozzle includes an inlet region and an outlet region for the composition, and a plane, extending in a longitudinal direction of the application nozzle. The outlet region includes a contact region for the application nozzle on a substrate standing perpendicular to the plane and an outlet opening for the composition. The contact region and the outlet opening are delineated from one another structurally as two separate sections that are kinked with respect to one another, and the contact region is at least partly slanted.
US09937511B2 Dispenser
A dispenser for dispensing liquid to pasty masses has a storage space and a dispenser head part, wherein a dispensing outlet allocated to the dispensing head part is formed, and the dispenser head part can be turned around a rotational axis (y) from a first position that impedes dispensing actuation into a second position that yields a standby position for dispensing, wherein an actuating part can be moved along a traversing axis (x) for dispensing mass through the dispensing outlet in the second position. In order to indicate an easy to handle dispenser, an outlet part exhibiting the dispensing outlet can be provided, so that the outlet part can be radially moved in relation to the traversing axis (x) while moving the dispenser head part from the first position into the second position and vice versa.
US09937510B2 Foundation container provided with discharge pump having short stroke distance and content spreading member
The present invention relates to a foundation container comprising an outer container main body (100) and an outer container lid (150) opened/closed while hinge-coupled to the outer container main body (100), the foundation container being provided with a discharge pump having a short stroke distance and a content spreading member and characterized by comprising: an inner container main body (300) formed inside the outer container main body (100); an inner container lid (400) for covering the upper part of the inner container main body (300); an inner container shielding plate (350) coupled to the upper inside of the inner container main body (300); the discharge pump (600) coupled to the center of the inner container shielding plate (350); the content spreading member (700) coupled to the upper part of the discharge pump (600); and an impregnated member (800) coupled to the upper part of the content spreading member (700).
US09937508B2 Electrostatic spraying device and method for controlling electrostatic spraying device
An electrostatic atomizer (100) includes a guard electrode (4) between an opening (11) and an opening (12). The guard electrode (4) is different from a spray electrode (1) and a reference electrode (2). A voltage between the spray electrode (1) or the reference electrode (2) and the guard electrode (4) is controlled to have a magnitude within a prescribed range smaller than a magnitude of a voltage between the spray electrode (1) and the reference electrode (2).
US09937507B2 Electrostatic spraying apparatus, and current control method for electrostatic spraying apparatus
An electrostatic atomizer (100) includes a spray electrode (1), a reference electrode (2), a control circuit (24) for controlling a value of a current at the reference electrode (2), and a high-voltage generator (22) for applying a voltage between the spray electrode (1) and the reference electrode (2). The control circuit (24) controls the value of the current at the reference electrode (2) so that the value of this current can be higher than a spray current corresponding to a prescribed spray amount of a substance.
US09937506B2 Motion guide apparatus cooling nozzles, motion guide apparatus with cooling nozzles, and motion guide apparatus cooling system
A motion guide apparatus cooling nozzle is provided which can gas-cool a motion guide apparatus. Cooling nozzles 1a and 1b of the present invention are mounted on a block 4 of the motion guide apparatus to cool at least one of a guide rail 2 and a block 4 that is assembled to the guide rail 2 via a rolling element 6 in such a manner as to be movable relatively. The cooling nozzles 1a and 1b include an inner passage 18 into which gas is introduced, an opening 12a configured to emit a gas flow introduced into the inner passage 18, a deflection surface 22a that is provided adjacently to the opening 12a to bend the gas flow emitted from the opening 12a, and a guiding surface 32a configured to attract gas outside the cooling nozzles 1a and 1b.
US09937503B2 Nanofluids for heat transfer applications
According to an implementation of the present subject matter, a method for producing stable nanofluids is described. The method includes mixing of a base fluid with a dispersant and a metal oxide powder to form a primary mixture. The base fluid is a heat transfer fluid and the metal oxide powder includes particles of size greater than 100 nm. The method further includes grinding the primary mixture to obtain a concentrated nanoparticle suspension where the dispersant is added to the primary mixture during the grinding after every pre-determined time period.
US09937500B2 Driving of jaw crusher elements
A jaw crusher including a body, a fixed jaw, a shaft which is arranged horizontally and in direction of a crushing surface of the fixed jaw, and a pitman which is eccentrically movable in relation to the shaft, wherein an electric motor is arranged between the pitman and the shaft. A mineral material processing plant. A method for driving a jaw crusher including a body, a fixed jaw, a shaft which is arranged horizontally and in direction of a crushing surface of the fixed jaw, and a pitman which is forming a crushing chamber with the fixed jaw, the method including moving the shaft eccentrically in relation to the pitman, the method further including the steps of arranging an electric motor between the pitman and the shaft and rotating the shaft by the electric motor.
US09937498B2 Artificial sieving structures
Disclosed herein is a device for electrophoresis comprising: a separation channel in a substrate; and a plurality of capillary-well motifs cascading along the separation channel, each of the plurality of capillary-well motifs comprising a well and a plurality of non-intersecting capillaries, wherein the capillaries are downstream from the well and fluidly connected thereto, an interface between the well and the capillaries comprises a step profile. Also disclosed is a method comprising: obtaining a substrate comprising an insulator layer of an insulator material; forming a well and a plurality of trenches in the insulator layer so that only the insulator material is exposed to an interior of the well and the plurality of trenches; nonconformally depositing a film into the plurality of trenches until the film pinches off top openings of the trenches and forms a tubular void therein; transforming the tubular void into a capillary by annealing the film.
US09937496B2 Methods of constructing a diagnostic cartridge and a fluid storage and delivery apparatus therefor
A method of constructing a point-of-care diagnostic apparatus and fluid storage and delivery apparatus therefor is provided. The method of constructing the fluid storage and delivery apparatus includes providing a flexible upper layer having a reservoir; providing a flexible lower layer having a valve member; providing a rigid substrate having an upper surface, a lower surface and a through port; disposing a fluid in the reservoir; and sandwiching the rigid substrate between the upper and lower layers and bonding the upper layer to the upper surface of the rigid substrate with the reservoir registered with the through port and bonding the lower layer to the lower surface of the rigid substrate with the valve member registered with the through port. The method of constructing the point-of-care diagnostic apparatus includes fixing the fluid storage and delivery apparatus to a rigid base in selective fluid communication with a reaction chamber.
US09937495B2 Hydrogel microstructures with immiscible fluid isolation for small reaction volumes
Techniques for hydrogel microstructures with oil isolation for small reaction volumes include providing a hydrogel microstructure that has a plurality of pores and a hydrogel frame surrounding the pores. The microstructure has a volume in a range from about 1 picoliter to about 10,000 picoliters and is configured to repel an immiscible fluid. Each pore of the plurality of pores has a pore size configured to pass the target molecule in a first solution. The microstructure is contacted with the first solution, and with a second solution that includes a reactant molecule that reacts with the target molecule to produce an observable product molecule. The microstructure is encompassed with the immiscible fluid for an extended observation duration from about 1 to about 10,000 seconds, wherein the immiscible fluid does not pass into the pores but traps the product in the microstructure. The observable product molecule is measured at some time during the observation duration.
US09937491B2 Method for preparing chiral ferrocene diphosphine ligand
A method for synthesizing (R)-(−)-1-((S)-2-diphosphino ferrocene)-ethyl-diphosphine by: 1) adding vinylferrocene, a chiral catalyst, and toluene to a first drying reactor; adding a phosphorus-hydrogen compound to the first drying reactor and allowing reactants in the first drying reactor to react; cooling the first drying reactor; adding water dropwise to the first drying reactor; extracting, drying, and recrystallizing a product to yield (R)-1-ferrocenylethyl-diphosphine; 2) adding the (R)-1-ferrocenylethyl-diphosphine and ether to a second drying reactor; adding a hexane solution including diethylzinc to the second drying reactor and allowing reactants in the second drying reactor to react; adding a phosphorus-chlorine compound dropwise to the second drying reactor, and heating and refluxing the reaction mixture in the second drying reactor; adding water to quench the reaction mixture in the second drying reactor; and extracting, drying, and recrystallizing the reaction mixture.
US09937489B2 Exhaust system without a DOC having an ASC acting as a DOC in a system with an SCR catalyst before the ASC
Catalyst articles having a first zone containing a first SCR catalyst and a second zone containing an ammonia slip catalyst (ASC), where the ammonia slip catalyst contains a second SCR catalyst and an oxidation catalyst, and the ASC has DOC functionality, where the first zone is located on the inlet side of the substrate and the second zone is located in the outlet side of the substrate are disclosed. The catalytic articles are useful for selective catalytic reduction (SCR) of NOx in exhaust gases, in reducing the amount of ammonia slip and in oxidizing organic residues. Exhaust systems containing the catalyst articles and methods of using the catalytic articles in an SCR process, where the amount of ammonia slip is reduced and hydrocarbon are oxidized by the ASC catalyst, are also described.
US09937482B2 Super absorbent polymer resin and method for preparing same
Disclosed herein are a superabsorbent polymer resin comprising agglomerated particles with a size of 450 μm or less, and a method for preparing the same. The superabsorbent polymer resin exhibits significant improvement in absorption rate and permeability.
US09937480B2 Purification apparatus including continuous reactors and purification method using continuous reactors
A purification apparatus and a purification method using the purification apparatus. A solution stored in a solution storage tank is diffused/agitated with an ultrasonic wave. An air compressor transfers the solution to a reactor. The solution is mixed in the reactor with a solvent fed through another passage to produce a reactant.
US09937479B2 Conversion of natural gas to liquid form using a rotation/separation system in a chemical reactor
A system and method are provided for the separation of hydrogen from natural gas feedstock to form hydrocarbon radicals. Aspects of the system include perpendicular magnetic and electric fields, a method of radical formation that separates hydrogen from the reaction process, and a separation method based on centrifugal forces and phase transitions. The gases rotate in the chamber due to the Lorentz force without any mechanical motion. Rotation separates gases and liquids by centrifugal force. The lighter species are collected from the mid region endpoint of the apparatus and fed back for further reaction. A new concept of controlled turbulence is introduced to mix various species. A novel magnetic field device is introduced comprised of two specially magnetized cylinders. A novel control of temperatures, pressures, electron densities and profiles by, RF, microwaves, UV and rotation frequency are possible especially when atomic, molecular, cyclotron resonances are taken into account. The electrodes can be coated with catalysts; the entire apparatus can be used as a new type of chemical reactor.
US09937476B2 Slurry phase apparatus
A method of operating a slurry phase apparatus includes feeding one or more gaseous reactants into a slurry body of solid particulate material suspended in a suspension liquid contained inside a vessel. The one or more gaseous reactants are fed into the slurry body through a gas distributor having downward facing gas outlets and are fed towards a fluid impermeable partition spanning across the vessel below the gas distributor. The partition divides the vessel into a slurry volume above the partition and a bottom volume below the partition. A differential pressure is maintained over the partition between predefined limits by manipulating or allowing changes in the pressure in the bottom volume by employing a pressure transfer passage establishing flow or pressure communication between the bottom volume and a head space above the slurry body.
US09937475B2 Dynamic seal to enable movement of a film or fiber through a pressurized space while maintaining a desired pressure
The present disclosure describes devices capable of continually and controllably passing a polymer film or fiber through a pressurized vessel, while maintaining a desired pressure inside the vessel. In certain embodiments, the devices of the present disclosure include dynamic seals capable of limiting the gas flow from the pressurized vessel to lower pressure environments.
US09937467B2 Exhaust gas processing device
An exhaust gas processing device preheats processing target exhaust gas in the presence of moisture with heat from at least either an electric heater or a heat exchanger and subsequently thermally decomposes the exhaust gas with an atmospheric pressure plasma. A device main body has a heating decomposition chamber therein. A plasma generator is installed at a top surface portion of the device main body. A reactor has a cylindrical shape and is installed within the device main body such that an upper end opening thereof is directed toward a plasma emission port of the plasma generator. A moisture supply unit is provided at an inlet side of the device main body. At least either the electric heater or the heat exchanger is disposed in a first space.
US09937465B2 Gas-producing apparatus and gas-producing method
A gas-producing apparatus that produces hydrogen or oxygen, includes: an electrolysis cell that produces hydrogen and oxygen through electrolysis of water; and a gas-liquid separation device that is connected to the electrolysis cell and that receives the water and the hydrogen or the oxygen, wherein the gas-liquid separation device includes a first chamber and a second chamber, the first chamber and the second chamber are separated by a partition wall, and a lower part of the first chamber and a lower part of the second chamber communicate with one another.
US09937464B2 Device for separating carbon dioxide using silicone separation film and method for manufacturing same
Provided are an apparatus for separating and collecting carbon dioxide and a method of separating carbon dioxide, and more particularly, an apparatus and method of selectively separating carbon dioxide from a byproduct gas using a difference in negative pressure and a difference in carbon dioxide concentration between the inside of a separator, which is made of a ceramic-coated porous silicone membrane and in which the byproduct gas flows, and the outside of the separator in which carbon dioxide is collected.
US09937458B2 Method for decarbonization of a fuel on board a vehicle
A method and apparatus for the reduction of carbon dioxide emissions by the on-hoard treatment of a portion or all of the hydrocarbon fuel used to power an internal combustion engine mounted in a conventional transportation vehicle, utilize known decarbonization technology to break the fuel's hydrogen-carbon bond. The compounds are then cooled and separated into (1) elemental carbon powder that is stored on-board for later recovery and industrial use, and (2) hydrogen, or a hydrogen-rich gas stream, that is burned as a fuel in the ICE and/or diverted to other on-board energy related applications.
US09937453B2 Contamination sensor, air purifier having the same and control method thereof
An air purifier includes a main body having an inlet configured to receive air and a discharger configured to discharge the air. The air purifier also includes a filter disposed within the main body and configure to purify contaminates from the air. The air purifier also includes a contamination sensor disposed adjacent to the filter and integrally includes a light emitter configured to emit a light toward the filter and a light receiver configured to receive the light emitted from the light emitter.
US09937452B2 Air filter with balanced seal
An air filter and dust collector are provided. In one embodiment, the air filter includes a filter element coupled at a first end to a end cap and at a second end to a first side of a rectangular filter flange assembly. The rectangular filter flange assembly includes a central aperture open to an interior region bounded by the filter element. A rectangular gasket is disposed on the second side of the filter flange assembly and circumscribes the central aperture.
US09937449B2 Filter with multiple media
A filter is provided having more than one density of media, or more than one type of media. Three or four types of media may be arranged. Some or all of the media may be of different density material from each other. A spacer grid separates at least two of the media apart. One or more flanges on the spacer each respectively space apart two of the media from each other at a location. The one or more flanges provide a respective flow path through the flange.
US09937444B2 Pumping system
According to embodiments described in the specification, a pumping system for use in a tailings pond is provided. The pumping system comprises a pump support and at least one mooring element coupled to the pump support. The at least one mooring element has an extended position for fixing the pump support to a bed of the tailings pond, and a retracted position for permitting movement of the pump support towards a shore of the tailings pond. The at least one mooring element is configured for transitioning from the extended position to the retracted position when a distance from the shore to the pump support exceeds a threshold as a result of a change to tailings pond geometry, and for returning to the extended position following movement of the pump support to reduce the distance below the threshold.
US09937435B2 Water vending apparatus
A water vending apparatus is disclosed. The water vending system includes a water vapor distillation apparatus and a dispensing device. The dispensing device is in fluid communication with the fluid vapor distillation apparatus and the product water from the fluid vapor distillation apparatus is dispensed by the dispensing device.
US09937433B2 Toy construction system
A toy construction system comprising a releasably connectable tendon or tether (“tendon”) to connect to at least two building blocks. The tendon being resiliently deformable and providing a range of motion for each of at least two blocks, relative to each other, in at least two Cartesian axes. The tendon having an engagement, and each block having a corresponding receiving element.
US09937431B2 Model train control system
A model train control system providing a more realistic modeling of the movement, sound, smoke, and lighting effects of a model train is disclosed. A number of dynamic inputs are used to control such effects. Novel features include providing a dynamic variable speed compensator, a dynamic engine load calculator, automatic dynamic momentum, an adjustable train brake, spectrum control, a velocity controller, pressure sensitive effects, a voice activated dispatcher system, a train location and information reporter network, two digit addressing, a traffic control system, accessory control, a model train Central Control Module, and removable memory modules.
US09937429B2 Variable sound generator
The device includes an accelerometer for sensing a parameter of movement, such as direction and/or magnitude. A pre-recorded sound is played in response to the sensed movement. The speed and/or pitch at which the pre-recorded sound is played is a function of the sensed movement parameter. There may be one or more pre-recorded sounds from which playback is chosen. In one embodiment, hardwired circuits set the characteristics of the generated sound in accordance with the accelerometer output. In a second embodiment, the software selects which pre-recorded sound to play and sets the characteristics of the sound based upon parameters sensed by the accelerometer.
US09937426B1 Passenger restraint for an amusement ride
A ride assembly includes a ride vehicle configured to carry one or more passengers and to move in a direction along a ride path, a first passenger seat of the ride vehicle having a seatback, where the first passenger seat is configured to seat a first passenger of the one or more passengers, and where the seatback is configured to rotate with respect to the ride vehicle from a loading position to an active position, a second passenger seat of the ride vehicle positioned behind the first passenger seat with respect to the direction, where the second passenger seat is configured to seat a second passenger of the one or more passengers, and a passenger restraint coupled to the seatback of the first passenger seat, where the passenger restraint is configured to secure the second passenger in the second passenger seat when the seatback is in the active position.
US09937424B2 Collaborative diplomacy mechanics
A collaborative diplomacy mechanics system for an online game is described. A player selects an ally to be engaged in a combat mode of an online social game against an enemy. The profile of the selected ally is retrieved. An ally power up weapon is generated based on the profile of the selected ally. The ally power up weapon is applied against a combat unit of an enemy of a player in the combat mode. The ally power up weapon can also be applied on a combat unit of the player in the combat mode.
US09937417B2 Interactive video game with different sized toys having different abilities within the video game
A video game includes a peripheral device that senses the presence and identity of toys near or on the peripheral. Each of the toys includes an identification device such as an RFID tag. Each of the toys is also associated with a corresponding game character or object. The peripheral device provides lighting effects based on characteristics of the game character or aspects of the game play sequence thereby enhancing the user's gameplay experience.
US09937416B2 Adaptive touch input controls
Various embodiments relating to providing touch input control of a computing device are disclosed. In one example, responsive to detecting a touch input on a display, a zero point of an adaptive virtual control may be established at a display location of the touch input. Responsive to a translation of the touch input on the display away from the zero point being greater than a radius of the adaptive virtual control, the zero point may be translated.
US09937413B1 Tile tray
This disclosure relates to a tile tray configured to facilitate manipulation of tiles. More specifically, the disclosed tile tray includes at least one cell including a bottom, at least one side abutting the bottom and extending upward therefrom, a node extending upward from the bottom and having a flat top surface, and a channel between the node and the at least one side. A tile positioned atop the top surface of the node may be manipulated by pressing a portion of the tile into the channel, thereby raising the opposite portion of the tile, the node serving as a fulcrum. The portion pressed into the channel may be moved along the channel, thereby rotating the tile, or the raised opposite portion may be grasped by a user to flip or move the tile.
US09937412B2 Fast money bingo
An improved bingo method and apparatus with a plurality of bingo balls numbered from 1 to 40. The plurality of bonus balls has various bonus values and each player has the capacity to place an individualized wager against a wagering establishment. A caller announces the start of the game and the value of a plurality of bonus balls, calls the bingo balls and bonus balls drawn from a random ball generator and announces the outcome of the game after a maximum of 21 spins of the random ball generator. Additional features include the possibility of a peer-to-peer wagering system where each player places identical wagers, plays against the set pool of entry fees and the house retains a percentage of the pot. The game further features a convenient table arrangement that can be played on the main floor of a wagering establishment or a large wagering room.
US09937411B2 Ball lottery apparatus
A ball lottery apparatus include a discharger adapted for discharging individually multiple lottery balls, a lottery field including multiple holes in which the discharged lottery balls can enter, a host controller for executing various controls, a retrieval mechanism adapted for retrieving the lottery balls. When a bingo game is played, the host controller can set the ball lottery apparatus to a normal mode in which an input time point at which each of the lottery balls discharged from the discharger is input to the lottery field depends on a predetermined rule, and to a dealer mode in which the input time point depends on human action.
US09937410B2 Tiles on shapes puzzle game
A tile-on-shape puzzle game is disclosed using a plurality of unique shape designs having one or more tile projections disposed on one or both faces of the shape. The tile projections are adapted to fit in a recess on a play tile. Optional play cards are used to provide clues or shape designations and scores. Shapes are played to form a puzzle, with each player selecting where to place a shape, thereby forming a unique puzzle each time the game is played. Tiles must fill every play space on a shape to form a word or numerical/shape sequence. Gameplay may be varied based on age and skill level, such as limiting the word or sequence direction to left-right, up-down, diagonal, or a combination thereof, or forming pathways with the puzzle.
US09937408B2 Wearable motorized device
A wearable motorized device comprising a shoe bracket, which has a ring-shaped structure and can be fastened to the middle part of a shoe; a wheel, which rotatably supports the shoe bracket to enable lateral skating and longitudinal walking; a driving motor, which rotationally drives the wheel; and a battery pack, which powers the driving motor. The wheels are not coaxially installed on the two sides of the shoe bracket to drive the wearer's longitudinal skating, but are installed on the ring-shaped shoe bracket, which can be fastened to the middle part of the shoe, to support the wearer's lateral skating and longitudinal walking. This way, the wearer can position his/her legs apart during skating; such that the skating stability is improved. Moreover, its general contour does not significantly exceed the contour of the shoe in the longitudinal direction, thus it will not strain the wearer when ascending or descending stairs. Therefore, a wearable motorized device with high skating stability and ease of use can be achieved.
US09937404B2 Golf shot reference device
An elongate substrate strip of durable material with a top side having a linear arrangement of equally spaced circles each representing a regulation size golf ball; the circles being numbered consecutively for use as a reference to indicate ball position and/or foot position. The linear strip may be formed in two segments that are pivotally attached to one another to allow for pivotal swinging movement of one segment relative to the other so that the segments can be extended to a straight linear configuration, a right angle (90 degree) configuration and to a collapsed low profile configuration. The device provides an aid for proper target alignment, body and feet alignment and ball alignment when practicing various golf shots with all types of clubs including woods, short/mid/long irons, wedges and putter. The device also serves as a reference for analyzing divots (i.e., fat, thin, pull, hook) after each practice golf shot.
US09937403B2 Golf training aid
A golf training aid comprising a base, a support arm, and an alignment rod or guide, wherein the base is positioned in front of the target golf ball when the golfer is in position behind the target golf ball. The arm is attached to the base and is normal to the direction of the stroke or swing, wherein the alignment rod or guide is held by the support arm directly above the target golf ball as viewed by the golfer. The system may further comprise an adjustable, telescoping, stationary, or detachable pole with a camera mount and/or camera attached to the pole top and may comprise a camera mount under the base.
US09937401B2 Simulated dribblefield
An dribblefield simulator improves a dribbler's dribbling skills where the invention simulates a partition of a game dribblefield where dynamic negative space exists between players. The dribblefield simulator can be a moving unit mounted on a fixed chassis with a plurality of dribblefield limiting parts mounted on the fixed chassis and a plurality of dribblefield limiting parts mounted on the moving unit. The chassis can also be a moving chassis. An optional dynamic feedback control system can be mounted on either the fixed or moving chassis that can receive signals from a game projectile and from a dribbler and control the moving units. Multiple moving units can be mounted on either the fixed chassis or the moving chassis.
US09937400B2 Automatic ball pitching machine
An automatic game ball throwing machine. The ball thrower includes a base, a support frame attached to the base, a drive wheel mechanism attached to the support frame, and a human-machine interface which enables customization of ball spin, speed and target location. A light source can be attached to the machine to illuminate each ball at one or more launch points. Further, a launching frame indexing element can be positioned to control the location of the ball target. A resident software program integrates the throwing machine, indexing element and human-machine interface, calculating pitch parameters and converting them to machine outputs to enable customization of pitch variety and characteristics.
US09937392B2 Golf club head with adjustable weight bar
A golf club head with means for adjusting a center of gravity along more than one axis is disclosed herein. The golf club head comprises at least one rectangular weight bar disposed within a recessed region on the sole and adjustable within the recessed region. One end of the weight bar is reversibly fixed to the sole with a connection element, while the other end includes an engagement feature that engages a retention feature at the edge of the recessed region. The retention feature provides multiple locations at the edge of the recessed region to which the engagement feature can be fixed, and when the weight bar is in a configuration desired by a golfer, the weight bar can be reversibly secured to the sole and immobilized within the recessed region by tightening the connection element. The weight bar may also include a slidable weight assembly.
US09937391B2 Golf club head
A hollow golf club head having a face part, a sole part, a side part, a crown part, and a hosel part, comprises one or more of inner ribs that are disposed on at least one of the sole part and the side part and that inwardly project from an inner surface of the one, one or more of outer ribs that are disposed on at least the one of the sole part and the side part and that outwardly project from an outer surface of the one, and one of the inner ribs is arranged between the outer ribs in a toe-to-heel direction.
US09937384B2 Multi-piece solid golf ball
In a golf ball having, in order, a core, an envelope layer, an intermediate layer and a cover, the following conditions are satisfied: (I) ball surface hardness>intermediate layer surface hardness>envelope layer surface hardness0.05 mm, (IV) (intermediate layer thickness−envelope layer thickness)>0.05 mm, and (V) (Cs−C10)/(C10−Cc)>1.0 (where Cs denotes the JIS-C hardness at the core surface, C10 the JIS-C hardness at a position 10 mm from a center of the core, and Cc the JIS-C hardness at the core center). The ball provides an excellent flight performance when struck by the average golfer, a feel that is both soft and solid, and an excellent durability to repeated impact.
US09937382B2 System and method for improving fitness equipment and exercise
In a first aspect, a method is provided that includes the steps of (1) providing a monitor for determining a level of exercise performance performed by an exerciser and for outputting a signal representative of the performance level; (2) using the monitor to measure a level of exercise performance performed by an exerciser; (3) outputting from the monitor a signal representative of the performance level; (4) providing a video game having a character, the video game inputting and being responsive to the performance level signal output by the monitor, the video game using the performance level signal to control a performance level of the video game character; and (5) while the exerciser is not exercising, controlling a performance level of the video game character based on a performance level signal output by the monitor.
US09937376B2 Entrapped roller of an elliptical
An exercise machine includes a frame and a resistance mechanism attached to the frame. A crank assembly in mechanical communication with the resistance mechanism, and the crank assembly includes a crank arm and a roller connected to the crank arm. A pedal assembly is movably attached to the crank assembly and movable in a performance of an exercise. The pedal assembly includes a pedal beam and a first tensioned element that spans at least a first portion of an underside of the pedal beam. A second tensioned element spans a second portion of the underside of the pedal beam and the roller is disposed between the first tensioned element and the second tensioned element.
US09937375B2 Independent suspension vibration damping mechanism of running platform of a treadmill
The invention belongs to the technical field of fitness equipment, in particular to the independent suspension vibration damping mechanism of running platform of a treadmill. It solves the problem that the shock effect of the existing treadmill is poor and so on. It includes the chassis and the runway frame. The front end of mentioned runway frame is suspended on the chassis by means of a suspension structure and when the runway frame is subjected to a downward force and forcing the front end of the runway frame to descend, the suspension structure can assist the front end of the runway frame to rise and reset. The independent suspension vibration damping mechanism of running platform of the treadmill has the advantages: simple structure, good stability, good shock absorption effect, providing shock absorption buffer to multiple locations of the treadmill, long span life, and high mechanical strength.
US09937374B2 Athletic training boot
A training boot having a half-platform sole, a boot upper disposed on the half-platform sole, and a weight housing disposed on the upper. A receptacle fastening member is disposed on the boot, configured and arranged for attaching a resistance band. The sole has a tread, which is interchangeable. A sensor housing is disposed on or in the boot. A heel strap is attached to the boot. Hooks or rings are attached to the half-platform sole, configured and arranged for attaching a resistance band. A training boot system includes two training boots with a resistance band removably attaching to the two boots.
US09937371B2 Pole vault swing-up rack
A pole vault swing-up rack includes a frame body with upper hooks and a lower push bracket. The rack is designed to hang vertically from a horizontal bar—as a pull-up bar—by the hooks. An athlete hanging from the pull-up bar in an upright vertical position may kick his/her legs and torso up to an inverted vertical position to simulate movement of a pole vault. The athlete's shoulders rest against vertical uprights of the rack to maintain the athlete's shoulders and body in front of a vertical plane as in a pole vault movement. A trainer can use the lower push bracket to assist the athlete in the kicking motion. The parts of the rack that come into contact with the athlete may be covered in foam padding and a rubber coating.
US09937367B1 Adjustable falling foot support device
The present invention comprises a shell, a fixing arrangement, a belt pulley, a main belt, and a breaking arrangement. The shell comprises a compartment defined therein and a belt outlet thereon. The compartment has an opening facing upward. The fixing arrangement detachably buckles the shell on safety harness. The belt pulley is pivotally arranged in the compartment by an axis and defines a winding room. The main belt is coiled in the winding room and has a first end affixed in the winding room, a second end pulled out from the shell through the belt outlet, and a supporting portion provided between the first end and the second end. The breaking arrangement comprises a plurality of blocks spacingly arranged on the shell, a first guiding groove radially arranged on the belt pulley, and a slider slidingly arranged in the first guiding groove to shift between a first position and a second position, such that when the slider shifts to the second position, the pulling position of the supporting portion is adjustable and when the slider shifts to the first position, the supporting portion is positioned for the user to step when hanging in the air.
US09937364B2 High intensity focused ultrasound with capacitive micromachined transducers
A medical instrument (900, 1000) comprising a high intensity focused ultrasound system (911) comprising an ultrasound transducer (102, 104, 202, 204, 302, 407, 08) with an adjustable sonication frequency. The ultrasound transducer comprises capacitive micromachined transducers (102, 104, 202, 204, 302, 407, 508). Execution of machine executable instructions by a processor causes the processor to: receive (700, 800) a treatment plan (924) descriptive of a target zone (908) within a subject (902); determine (702, 802) a traversal distance (926) through the subject to the target zone using the treatment plan, wherein the traversal distance is descriptive of the traversal of ultrasound from the ultrasound transducer to the target zone; determine (704, 804) a sonication frequency (829) using the traversal distance for focusing the sonication volume onto the target zone; and sonicate (706, 806) the target zone using the high intensity focused ultrasound system at the sonication frequency.
US09937362B2 Dynamic energy control of a charged particle imaging/treatment apparatus and method of use thereof
The invention comprises a beam adjustment method and apparatus used to perform energy adjustments on circulating charged particles in a synchrotron previously accelerated to a starting energy with a traditional accelerator of the synchrotron. The beam adjustment system uses a radio-frequency modulated potential difference applied along a longitudinal path of the circulating charged particles to accelerate or decelerate the circulating charged particles. Optionally, the beam adjustment system phase shifts the applied radio-frequency field to accelerate or decelerate the circulating charged particles while tightening spatial distribution of a grouped bunch of the circulating charged particles. Optionally, the beam adjustment system simultaneously radially focuses the circulating charged particles using two or more gaps with focusing and/or defocusing edges. The beam adjustment system facilitates treating multiple layers or depths of the tumor without hysteresis and/or between the repeating slow steps of reloading the synchrotron.
US09937353B2 Systems and methods for increasing stimulation dose
According to an embodiment of a method performed by an implantable medical device to deliver a neural stimulation therapy to a patient, a lower dose of the neural stimulation therapy is delivered to the patient. The dose of the neural stimulation therapy is automatically increased from the lower dose to a higher dose, and the higher dose of the neural stimulation therapy is delivered to the patient. A trigger that is controlled by the patient is detected, and the dose of the neural stimulation therapy is automatically returned from the higher dose back to the lower dose in response to detecting the trigger.
US09937352B2 Rate responsive cardiac pacing control using posture
An implantable rate responsive pacemaker includes a sensor module configured to produce an activity signal correlated to a metabolic demand of a patient and a posture signal correlated to patient posture. The pacemaker further includes a pulse generator configured to generate and deliver pacing pulses to a patient's heart via a pair of electrodes coupled to the pacemaker. A control module is coupled to the pulse generator and the sensor module and is configured to determine a sensor indicated pacing rate from the activity signal, compare the posture signal to verification criteria for confirming an exercising posture of the patient, and withhold an adjustment of a pacing rate to the sensor indicated pacing rate responsive to the verification criteria not being met.
US09937351B2 Methods and systems for lowering blood pressure through reduction of ventricle filling
Systems and methods for reducing ventricle filling volume are disclosed. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated at a consistent rate to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.
US09937345B2 Cochlear implant
A device for implantation into a scalia tympani of a cochlea is disclosed. The device comprises blocks and compliant elements interconnecting the blocks with one of the compliant elements disposed between each pair of adjacent blocks. The compliant elements impart flexibility to the device in a plane of curvature of the cochlea and impart stiffness to the device out of the plane of curvature of the cochlea. The device further comprises piezoelectric elements with at least one of the elements disposed the blocks. Each piezoelectric element comprises at least one piezoelectric sensing unit and at least one electrode for transmitting the electrical signal to the auditory nerve. The device further comprises communication lines for transmitting an electrical signal through the device with one of the communication lines disposed between each pair of blocks and parallel to the compliant element.
US09937344B2 Waveforms for electrical stimulation therapy
In some examples, the disclosure relates to a systems, devices, and techniques for delivering electrical stimulation therapy to a patient. In one example, the disclosure relates to a method including delivering a series of pulses with alternating pulse polarities to a gastrointestinal tract of a patient. The series of pulses includes at least a first pulse of a first polarity, a second pulse of a second polarity, and a third pulse of the first polarity, where the first, second and third pulses are delivered in direct succession and in that order. The first and second pulses are separated by a first time delay and the second and third pulses are separated by a second time delay. In some examples, each of the first and second time delays depend on the frequency that the series of pulses are delivered.
US09937343B2 Electrostimulation skin massage devices
A hand held electrostimulation device has a handle having a first side member and a second side member. At least one first electrode is provided on the first side member and at least one second electrode is provided on the second side member. The first side member is longer than the second side member, which is connected with the first side member at a position intermediate the ends of the second side member. The handle is configured so that a user can cause relative movement of the first and second side members from a rest position and is resiliently biased to return to the rest position to cause relative movement of the first and second electrodes to massage skin engaged by the electrodes while applying electricity to the skin via the electrodes.
US09937342B2 Shifting of electrical stimulation electrode combinations among differently sized electrode arrays
The disclosure provides techniques for parameter-directed shifting of electrical stimulation electrode combinations. An external programmer permits a user to shift electrode combinations, e.g., along the length of a lead or leads. The external programmer accepts shift input and causes an electrical stimulator to shift electrode combinations as indicated by the input. Different sets of electrodes may have different electrode counts. For example, an array of electrodes carried by one lead may have a greater number of electrodes than an array of electrodes carried on another lead. The disclosure provides techniques for shifting electrode combinations among leads with different electrode counts. For example, an external programmer may execute shifts in a series of shift operations, where the number of shift operations along the length of a lead having a greater electrode count is greater than the number of shift steps along the length of a lead having a lesser electrode count.
US09937334B2 Catheter with customizable connector
A catheter, and preferably a urinary catheter, is disclosed, comprising an elongate shaft with a catheter insertion end and a flared connector connected to the elongated shaft opposite to the catheter insertion end. The flared connector forms a catheter connector end. Further, a gripping sleeve is fixedly connected to the flared connector, and arranged to enclose at least part of, and preferably essentially the whole, flared connector, apart from the catheter connector end. Hereby, a standard catheter can easily be customized for various use situations and users with different needs, in terms of e.g. gripping and manipulation possibilities. A method for producing such a customized catheter is also disclosed.
US09937330B2 System, method, and kit for providing the diameter of a balloon during treatment
Medical systems are described herein. More particularly, the disclosure relates to medical systems, methods, and kits useful in providing the diameter of a balloon during the performance of a procedure. An exemplary medical system comprises a balloon catheter, an inflation device, and a measuring device having one or more indicia. Each indicium of the one or more indicia has a form that corresponds to the nominal value of a balloon diameter.
US09937327B2 Anchor systems and methods
Some embodiments of a medical device anchor system include an anchor device that receives a medical instrument (such as a catheter or the like) and secures the instrument in place relative to a skin penetration point. In some circumstances, the anchor device may allow the anchor device to be used after medical instrument is already in place without the need for a second penetration point for the anchor device.
US09937320B2 Method of dissecting tissue
A method of dissecting tissue includes inserting a magnetized catheter into a urethra; magnetically pushing a tool away from the urethra with the magnetized catheter; and dissecting tissue posterior of the urethra with the tool.
US09937318B2 Safe urinary catheter and manufacturing method
A urinary catheter may include a catheter shaft and a connector coupled with the proximal end of the catheter shaft. The connector may have a first arm ending in a fluid outlet configured to allow urine to flow out of the urinary catheter and a second arm with an aperture and ending in an inflation inlet used for introducing inflation fluid into the urinary catheter. The catheter may further include a primary lumen, an inflation lumen, a retention balloon mounted to the catheter shaft proximal to a fluid inlet and over a distal filling hole, and a pilot balloon mounted on the second arm of the connector over the aperture. The pilot balloon inflates at an inflation pressure that is higher than the inflation pressure of the retention balloon and lower than a predetermined pressure threshold.
US09937316B2 Connecting-system kit for a respiratory humidifier
A liquid-container/ventilation-tube kit for a ventilation system that includes (a) a ventilator, (b) a respiratory humidifier having a housing and a liquid container, the housing having a pair of first electrical contact elements, (c) a first inhalation tube extending from the respiratory humidifier to a Y-piece, (d) a second inhalation tube extending from the ventilator to the respiratory humidifier, and (e) an exhalation tube extending from the Y-piece to the ventilator, the kit including the liquid container having a pair of first connection elements for removable connection of the first and second inhalation tubes thereto, and a pair of second connection elements each attached to a respective one of the first and second inhalation tubes and by which each of the inhalation tubes is pneumatically connected to a respective one of the first connection elements along a first connecting direction, each second connection element having a second electrical contact element that is positioned and arranged such that electrical connection with a respective one of the first electrical contact elements is possible in both of two ways, one when the pneumatic connection of the respective ventilation tube to the liquid container is effected after the liquid container has been inserted into the housing and the other when the liquid container is inserted into the housing after the pneumatic connection of the ventilation tubes to the liquid container has been effected.
US09937312B2 Delivery of respiratory therapy with foam interface
An air delivery system for providing a supply of air from a source of air at positive pressure to an interfacing structure located at the entrance to the airways of a patient includes a manifold adapted to connect with the supply of positive air pressure and at least one tube connected to the manifold and adapted to deliver the supply of air to the interfacing structure. Each tube is structured to allow movement between an open phase in which the tube allows the passage of air and a collapsed phase in which the tube is collapsed. Each tube is structured such that weight of a typical patient's head against bedding apparel is sufficient to collapse the tube from the open phase to the collapsed phase.
US09937303B1 Two-stage apparatus and method for generating and concentrating fine particle aerosols
A system and a method for generating a respirable dry powder aerosol (15) from a liquid solution or liquid suspension at a respirable dry powder aerosol volume flow (91). A liquid aerosol generating nozzle (3) generates from the liquid solution or liquid suspension a liquid aerosol (13) that is diluted by dilution gas (4) and dried in a cylindrical evaporation chamber (6) to generate a dry powder aerosol (14) that is subsequently concentrated by a cylindrical single linear slit aerosol concentrator (9). The system and method may include heliox as a gas, specifically dilution gas (4), for enhancing both the drying process in the cylindrical evaporation chamber (6) and for enhancing the concentration efficiency, but also as a nozzle gas (2) for enhancing generating the liquid aerosol (13) from the liquid solution or liquid suspension.
US09937298B2 Tissue penetration device
A tissue penetration device includes a magnetic source that produces a controllable magnetic field in a magnetically active region adjacent the magnetic source. A magnetic member is disposed at least partially in the magnetically active region. A permanent magnet is disposed at a proximal end of the magnetically active region for zeroing the position of the magnetic member while the tissue penetration device is inactive.
US09937297B2 Medicament delivery device
A medicament delivery device includes a housing; a hollow plunger rod; a dose drum concentrically arranged between the housing and plunger rod and movable when setting and delivering a dose; and a plunger rod driver. The driver includes a hollow ratchet arm drum movably arranged within the plunger rod and fixed to the dose drum, with the arm drum and rod releasably coupled; a dose activator having a longitudinal rod movably arranged within and releasably coupled to the arm drum; a dose setting knob fixed to the dose activator and releasably coupled to the arm drum; and a resilient element arranged between the arm drum and dose activator that biasses them in a direction decoupling the longitudinal rod from the arm drum and coupling the knob with the arm drum, such that during dose setting, turning the knob forces the arm drum and dose drum to rotate together.
US09937295B2 Syringe for mixing and ejecting an active pharmaceutical ingredient
A syringe (1) for mixing and ejecting an active pharmaceutical ingredient is disclosed. The syringe (1) comprises a syringe body (2) defining a first lumen (8), a first plunger (4) arranged movably in said first lumen (8), said first plunger (4) being hollow, thereby defining a second lumen (9) being separated from the first lumen (8), and a second plunger (5) arranged movably in said second lumen (9). A liquid diluent is contained in one of the first lumen (8) and the second lumen (9), and an active pharmaceutical ingredient is contained in the other of the first lumen (8) and the second lumen (9). The second plunger (5) is movable in such a manner that the active pharmaceutical ingredient and the liquid diluent are brought together, e.g. in the first lumen (8) or in the second lumen (9), thereby causing the active pharmaceutical ingredient to be diluted by the diluent, and the first plunger (4) and/or the second plunger (5) is/are movable in such a manner that diluted active pharmaceutical ingredient can be ejected from the syringe (1). The syringe (1) provides a single device for mixing and ejecting the active pharmaceutical ingredient. This reduces the risk of contamination, and the syringe (1) can be easily operated by an untrained user.
US09937290B2 Constant rate fluid delivery device with selectable flow rate and titratable bolus button
A wearable, self-contained drug infusion device is disclosed that is capable of achieving the precise flow rate control needed for dose-critical drugs such as insulin. In preferred embodiments of the device, at least two flow channels are utilized in conjunction with a series of valves for providing a user with selectable, constant flow rate control. The device can be made with small dimensions so that it can be worn by the user with a minimum of discomfort and inconvenience. In addition, the simple mechanical nature of the device provides the user with close control over the flow rate, which is required for safe and effective delivery of insulin and other drugs. Also, the absence of electronic components allows the device to be manufactured inexpensively. The device is provided with a first channel that is long and narrow, functioning as a flow restrictor. The first channel is preferably provided in a serpentine pattern. A second channel is also provided that has a larger cross section so that flow is not restricted. A series of valves are used to force the flow of fluid through a selectable portion of the serpentine portion of the first channel before entering the remainder of the second channel and flowing to the delivery cannula. In one embodiment of the device, a needle port is provided in fluid communication with the delivery cannula for delivering bolus injections. In another embodiment, a bolus button is provided for delivering bolus injections. A flow restrictor is preferably included in the bolus button to limit the rate at which the bolus button refills.
US09937284B2 Systems for upgrading ventricle assist devices
Systems and devices for an updatable blood pump are disclosed herein. The blood pump can be part of a mechanical circulatory support system that can include a system controller and the blood pump. The blood pump can include a rotary motor and a control unit that can communicate with the system controller. The system controller can initiate the update process and can provide the update to the blood pump. Upon initiation of the update process, the control unit can stop the rotary motor. While the rotary motor is stopped, the blood pump can be updated. At the completion of the update, the rotary pump can be restarted.
US09937283B2 Adjunct material to provide drug elution from vessels
Adjunct material is provided that has multiple reservoirs formed therein and releasably carrying a plurality of vessels that each retain at least one medicant. An implantable adjunct has at least one bioabsorbable polymer configured to maintain the vessels within a reservoir. Disruption of the at least one bioabsorbable polymer allows release of the vessels from at least one of the reservoirs. A rate of the vessels' release can be controlled by a degradation rate of the at least one bioabsorbable polymer. The released vessels are, in turn, disrupted to thereby cause at least one medicant disposed therein to release and thus provide a desired effect on tissue in-growth.
US09937278B2 Biocompatible and biodegradable gradient layer system for regenerative medicine and for tissue support
The present invention is directed to a biocompatible and preferably biodegradable gradient layer system comprising at least one set of layers comprising a biocompatible and preferably biodegradable cross-linked polymer and at least one biocompatible and preferably biodegradable support layer, wherein a gradient is preferably formed with respect to the mechanical and/or physical properties of one or more layers of the at least one set of layers comprising a biocompatible and biodegradable cross-linked polymer and/or the at least one biocompatible and preferably biodegradable support layer. The at least one support layer preferably comprises a biocompatible and preferably biodegradable meltable polymer and/or a biocompatible and incorporable material. This biocompatible and preferably biodegradable gradient layer system may be used as a biomaterial for regenerative medicine, particularly as a wound dressing or for tissue support. The present invention also provides means utilizing said inventive gradient layer system and methods for producing same.
US09937277B2 Hot melt adhesive
A hot melt adhesive material and articles made using the hot melt adhesive to assemble structures in an article. The adhesive material typically is manufactured by blending amorphous polymer with a heterophase polymer having crystallinity into an adhesive composition.
US09937269B2 RTEF-1 variants and the use thereof for inhibition of angiogenesis
Dominant negative (DN) variants of transcriptional enhancer factor 1-related (RTEF-1) are described. DN RTEF-1 polypeptides may be directly targeted to cells or delivered in nucleic acid expression vectors to alter cellular transcription. Methods for inhibiting VEGF production and thereby treating angiogenic disorders such as cancer are described. For example, in certain aspects, DN RTEF-1 may be used to treat angiogenic disorders of the eye such as age related macular degeneration (AMD).
US09937266B2 Oligomer-containing benzamide-based compounds
The invention relates to (among other things) oligomer-containing benzamide-based compound compounds. A compound of the invention exhibits one or more advantages over corresponding compounds lacking the oligomer.
US09937265B2 Self-assembling peptide and polysaccharide complexes
Novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefore are described. The novel self-assembling peptide complexes have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. Methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth are also described.
US09937264B2 Glycosylated polypeptide and drug composition containing said polypeptide
[Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.
US09937263B2 Carrier for use in delivering drug, conjugate, composition comprising same, and method for administrating same
The present invention provides a vesicle, a conjugate, a composition comprising the vesicle or the conjugate, for use in delivering a drug to the brain, and a method for administering the same. The composition of the present invention is a composition for administration to a subject according to a dosing regimen, comprising a carrier for drug delivery, wherein the dosing regimen comprises administering the composition to a subject who has been fasted or caused to have hypoglycemia and inducing an increase in blood glucose level in the subject, and the carrier is modified at the outer surface thereof with a GLUT1 ligand.
US09937262B2 Prodrugs of naproxen and diclofenac
The present invention relates to a compound of formula (I): wherein R1 is R3-IPU and R2 is the acyloxy residue of diclofenac or naproxen, and specified by the following structures (A) wherein OH—R3-IPU is selected from (B) and R4 and R5 may be the same or different selected from (C) and salts, solvates and hydrates thereof.
US09937261B2 Combination therapy comprising a liposomal prodrug of mitomycin C and radiotherapy
A method of treating neoplasia in a subject in need of treatment is provided by administering to the subject an amount of a prodrug of mitomycin C that yields a therapeutically effective amount of mitomycin C, in combination with radiation therapy. In one embodiment, the prodrug of mitomycin C is a liposomal-prodrug of mitomycin C. Together, the prodrug of mitomycin C and radiation therapy provide a synergistic antineoplastic effect.
US09937258B2 Composition for application to a nasal mucosa comprising a methylcellulose
A composition designed for application to a mucosa comprises a tonicity-adjusting agent, a methylcellulose, and a liquid diluent, wherein the methylcellulose has anhydroglucose units joined by 1-4 linkages wherein hydroxy groups of anhydroglucose units are substituted with methyl groups such that s23/s26 is 0.36 or less, wherein s23 is the molar fraction of anhydroglucose units wherein only the two hydroxy groups in the 2- and 3-positions of the anhydroglucose unit are substituted with methyl groups and wherein s26 is the molar fraction of anhydroglucose units wherein only the two hydroxy groups in the 2- and 6-positions of the anhydroglucose unit are substituted with methyl groups.
US09937253B2 Functional influenza virus-like particles (VLPS)
The present invention discloses and claims virus like particles (VLPs) that express and/or contains seasonal influenza virus proteins, avian influenza virus proteins and/or influenza virus proteins from viruses with pandemic potential. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising VLPs of the inventions. The invention also includes methods of making and administrating VLPs to vertebrates, including methods of inducing substantial immunity to either seasonal and avian influenza, or at least one symptom thereof.
US09937251B2 Utilization of recombinant influenza viruses and modified vaccinia ankara virus (MVA) with genes that encode for the Toxoplasma gondii SAG1 and SAG2 surface proteins, as vaccines against toxoplasmosis
The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant influenza viruses and modified vaccinia Ankara viruses (MVA) with genes that encode for the T. gondii parasite SAGI (MVA) and SAG2 (MVA and influenza) proteins, by means of a homologous recombination technique between two transfer vectors (for construction of MVA virus) and reverse genetics (for construction of influenza virus). Additionally, the present invention describes a vaccine composition using recombinant influenza viruses and modified vaccinia Ankara viruses (MVA), or recombinant adenoviruses and modified vaccinia Ankara viruses (MVA), for immunization against infections caused by the T. gondii parasite.
US09937250B2 Immunogenic tumor associated stromal cell antigen peptides and methods of their use
Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides are useful for methods of eliciting an immune response. In additional examples the peptides are useful for methods of treating cancer. Methods for decreasing vascularization of a tumor using a Protein Delta Homolog 1 (DLK1) protein or a nucleic acid encoding the protein are also disclosed.
US09937249B2 Mesoporous silica compositions for modulating immune responses
A composition comprising mesoporous silica rods comprising an immune cell recruitment compound and an immune cell activation compound, and optionally comprising an antigen such as a tumor lysate. The composition is used to elicit an immune response to a vaccine antigen.
US09937247B2 Universal cancer vaccine
Described herein are compositions of matter and methods for treating cancer. The compositions comprise altered human telomerase polypeptides containing T cell epitopes that have been altered to increase immunogenicity. The methods comprise administration of the polypeptides or nucleic acids, such as DNA or RNA encoding the polypeptides, to individuals afflicted with, or at risk of, developing cancer.
US09937245B2 Highly pure neurotoxic component of a botulinum toxin, process for preparing same, and uses thereof
The present invention relates to a process for preparing a highly pure neurotoxic component of a botulinum toxin by cultivating clostridium botulinum under conditions that allow production of a botulinum toxin, and isolating the neurotoxic component from the botulinum toxin. In addition, the present invention relates to a highly pure neurotoxic component of a botulinum toxin obtainable by the process of the present invention and uses thereof.
US09937243B2 Sialylated glycoprotein compositions and uses thereof
The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
US09937235B2 Lipidated peptides as anti-obesity agents
Lipidated peptides, analogs of both forms of the prolactin-releasing peptide, PrRP31 and PrRP20, represent anorexigenic compounds that lower food intake and function in the brain after peripheral administration. The analogs PrRP31 and PrRP20 lipidated at the N-terminus by myristic or palmitic acids bind with high affinity to the endogenous receptor GPR10 in the rat pituitary cell line RC-4B/C and CHO cell line with transfected human receptor. These lipidated peptides also significantly decrease, in a dose-dependent manner, the food intake in fasted mice and have similar effects in comparable doses as centrally administered natural PrRP31, these effects are, however, stronger and longer lasting. Lipidation of an effective anorexigenic neuropeptide PrRP induces a central effect after peripheral administration and thus makes the lipidated analogs of PrRP a promising anti-obesity drug.
US09937231B2 Methods and agents for treating Alzheimer's disease
The present disclosure provides compositions and methods useful for treating or preventing diseases or disorders where beta amyloid accumulation or aggregation contributes to the pathology or symptomology of the disease, for example Alzheimer's disease.
US09937229B2 Methods of treatment using hemopexin compositions
The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying haptoglobin and hemopexin from the same starting material, and uses thereof.
US09937225B2 Topical formulations and uses thereof
Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.
US09937219B2 Purified cannabinoid product and system and method for producing the same
A purified lipid-based solution including cannabinoids is manufactured by providing a lipid solution including an array of triglycerides, cannabinoids and water soluble contaminants. Adding water to the lipid solution to create a mixture and heating the mixture in a pressure vessel to a temperature above the melting point of the lipid solution. The mixture is agitated to dissolve the water soluble contaminants and electrocoagulated. The mixture is cooled to cause the triglycerides and cannabinoids to solidify. The water is separated from the mixture to remove water soluble contaminants, precipitated contaminants, suspended solids and colloids from the mixture to yield a purified lipid solution.
US09937218B2 Systems and methods for cannabinoid and terpene extraction and purification
A method for preparing a purified cannabis extract may comprise extracting a crude extract from cannabis solids, dewatering the crude extract, removing chlorophyll from the crude extract, and distilling the crude extract thereby creating a purified cannabis extract. The extracting step may include contacting crude cannabis solids with an organic ester, thereby creating the crude extract and waste solids. The dewatering step may include contacting the crude extract with a solid dewatering agent and filtering the crude extract from the solid dewatering agent. The removing chlorophyll step may include contacting the crude extract with a solid absorbent agent, and filtering the crude extract from the solid absorbent agent.
US09937217B2 Method of inhibiting ABCG2 and related treatments
Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of inhibiting ABCG2 or MRP1 in a mammal afflicted with cancer, and a method of increasing the bioavailability of an ABCG2 substrate drug in a mammal. The methods comprise administering peliomycin and other compounds described herein.
US09937216B2 Method for suppressing proliferation and/or inducing apoptosis of cancer cells
It is to provide an agent for suppressing proliferation and/or inducing apoptosis of cancer cells that can be used for the treatment and chemoprophylaxis of cancer, wherein the agent is easily accessible and ingestible in daily dietary life and is prepared using a naturally-derived ingredient with reduced side effects, and a method for suppressing proliferation and/or inducing apoptosis of cancer cells in a subject in need thereof, and the like. By administering an agent for suppressing proliferation and/or inducing apoptosis of cancer cells comprising Sargassum horneri or a processed product thereof to a subject in need thereof, the proliferation of cancer cells can be inhibited and apoptosis of cancer cells can be induced in the subject.
US09937213B2 Composition comprising L. rhamnosus GG
The present finding relates to a composition comprising the probiotic Lactobacillus rhamnosus GG (ATCC 53103) for use in the prevention and/or treatment of herpes labialis and to a composition comprising the probiotic bacterial species and a soluble prebiotic fiber.
US09937212B2 L. johnsonii LA1, B. longum NCC2705 and immune disorders
The present invention generally relates to the field of probiotics, and in particular to preventing and/or treating inflammatory and infectious disorders, for example by boosting the endogenous antimicrobial defences. One embodiment of the present invention is a composition comprising a combination of L. johnsonii (La1, NCC 533, deposit number CNCM I-1225) and Bifidobacterium longum NCC2705 (deposit number CNCM I-2618). This composition may be used in the treatment or prevention of disorders related to the immune system including infections.
US09937210B2 Method for isolating fraction having anti-inflammatory or osteoarthritis-inhibiting effects by using oyster shell chips
The present invention relates to a method for isolating a fraction having anti-inflammatory or osteoarthritis-inhibiting effects by removing impurities and washing oyster shells, which are produced during a process of producing oysters, drying same, forming a powder from the oyster shells, and adding anhydrous citric acid to same for a reaction, obtaining a reaction product, and isolating a supernatant, which is obtained by centrifugally separating the reaction product, by means of ultrafiltration. By adding the anhydrous citric acid to the oyster shell chips for the reaction at a relatively low temperature, the present invention provides superior advantages, such as significantly reducing energy costs and isolating the fraction having the anti-inflammatory or osteoarthritis inhibiting effects through a simple method.
US09937206B2 Compositions and methods of treating T cell mediated disorder
A method of generating a CD4+FoxP3+ Treg cell, the method includes administering at least one complement antagonist to a naive CD4+ T cell at an amount effective to substantially inhibits C3a receptor (C3aR) and/or C5a receptor (C5aR) signal transduction in the CD4+ T cell, induce TGF-β1 expression of the CD4+ T cell, and induce differentiation of the of the naive CD4+ T cell into a CD4+FoxP3+ Treg cell.
US09937202B2 Topical nitric oxide systems and methods of use thereof
The present invention generally relates to compositions and methods for transdermal drug delivery. The compositions can be used in a variety of applications, including treating erectile dysfunction or sexual dysfunction, treating wounds, or causing or promoting hair growth. For example, in one aspect, the present invention is generally directed to compositions for delivery of nitric oxide. The nitric oxide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin, e.g., onto the penis, vulva, or other suitable portion. The composition can also be applied to a mucosal surface. In some embodiments, a composition comprising nitric oxide is unexpectedly stable.
US09937200B2 Skin compositions and methods of use thereof
Compositions and methods useful for delivering an agent to a subject are described. The methods include applying to the subject's skin a composition comprising a reactive reinforcing component, a cross-linking component, and one or more agents, wherein the cross-linking component catalyzes an in situ reaction on the skin, thereby delivering the agent to the subject.
US09937197B2 Wound healing compositions and treatments
This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.
US09937195B2 Edible energy composition
The disclosure relates to an edible energy composition that includes a methylated xanthine, a choline derivative and a flavorant.
US09937190B2 Use of aminosalicylates in diarrhoea-predominent irritable bowel syndrome
A method for the treatment or prophylaxis of non-inflammatory bowel diseases, diarrhea-predominant irritable bowel syndrome or other non-specific bowel disorder is disclosed comprising administering to a patient in need of such treatment or prophylaxis an effective amount of balsalazide, or a 4-ASA or 5-ASA compound modified to include a 4-ABA side chain, or a salt or a derivative thereof, or a composition comprising balsalazide the modified compound, or a salt or a derivative thereof together with a suitable carrier. Use of balsalazide, a 4-ASA or 5-ASA compound modified to include a 4-ABA side chain, or a salt or derivative thereof, for the manufacture of a medicament for the treatment or prophylaxis of non-inflammatory bowel diseases, diarrhea-predominant Irritable Bowel Syndrome or other non-specific bowel disorder is also disclosed.
US09937184B2 Theobromine compositions useful for increasing fetal weight gain and enhancing bone properties
Compositions and methods for culturing cells with theobromine are provided, as well as cells derived thereby. Theobromine compositions for enhancing bone formation, increasing bone density, increasing interconnections of internal bone, increasing bone mass, treating cartilage and/or bone defects, increasing fetal birth weight, preventing tooth decay, remineralizing a tooth surface, treating dentine hypersensitivity, and application to a bone site to promote new bone growth at the site are also provided.
US09937178B2 Methods of identifying and using MDM2 inhibitors
Methods of treating subjects with cancer and screening for MDM2 inhibitors that may be effective cancer therapeutics are provided herein. The cancers that may be treated using MDM2 inhibitors using the methods described herein include those that are or may become resistant to treatment with tyrosine kinase inhibitors. Methods of treating subjects with cancers that have, or develop in response to treatment with tyrosine kinase inhibitors, elevated levels of MDM2, Mcl-1 or PP5 or decreased levels of Huwe1 or CAS using MDM2 inhibitors are provided herein. The MDM2 inhibitors may be effective at treating these cancers alone or in combination with a tyrosine kinase inhibitor regardless of p53 status (mutant or wild-type) of the cancer.
US09937177B2 Therapeutic compounds
The invention provides a compound of formula I: wherein X, Y, Z have any of the values defined in the specification or a salt thereof. The compound is useful as anti-cancer agents. The invention also provides processes and intermediates disclosed herein that are useful for preparing a compound of formula I or a salt thereof.
US09937174B2 Combinations of histone deacetylase inhibitors and bendamustine
The invention relates to pharmaceutical combinations comprising an HDAC inhibitor and bendamustine; pharmaceutical compositions comprising the same; and methods of using such combinations and compositions for treating lymphoma in a subject in need thereof.
US09937171B2 Methods of blocking the CXCR-4/SDF-1 signaling pathway with inhibitors of bruton's tyrosine kinase
In some embodiments, the present invention relates to novel small molecule inhibitors that block the CXCR4-SDF-1 signaling pathway by directly inhibiting members of the Tec family of kinases, namely Bruton's tyrosine kinase (BTK), and their use in treating diseases in which pathogenesis is mediated by the CXCR4/SDF-1 signaling pathway.
US09937168B2 Nicotine-containing pharmaceutical compositions
A composition intended to be employed for therapeutic purposes incorporates nicotine and at least one other nicotinic compound. Representative forms of nicotine can be as a free base (e.g., as a mixture of nicotine and microcrystalline cellulose), as a form of nicotine salt (e.g., as nicotine bitartrate) or as nicotine polacrilex. The other nicotinic compound is a compound that can be considered to bind selectively to certain nicotinic receptor subtypes, and particularly those of the central nervous system. For example, the other nicotinic compound can be a compound that binds selectively to the nicotinic receptor subtypes α7 or α4β2. The composition is useful for treatment of central nervous system conditions, diseases and disorders, and as a nicotine replacement therapy.
US09937167B2 SHIP1 modulators and methods related thereto
Compounds of formula (I): where n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of formula (I) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof.
US09937166B2 Use of levocetirizine and montelukast in the treatment of traumatic injury
The embodiments described herein include methods and formulations for treating lung and brain injury. The methods and formulations include, but are not limited to, methods and formulations for delivering effective concentrations of levocetirizine and montelukast to a patient in need. The methods and formulations can comprise conventional and/or modified-release elements, providing for drug delivery to the patient.
US09937165B2 Pharmacological chaperones for treating obesity
The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface.
US09937164B2 Opioid formulations
A depot precursor formulation comprising: a) a controlled-release matrix; b) at least oxygen containing organic solvent; c) at least 12% by weigh of at least one active agent selected from buprenorphine and salts thereof, calculated as buprenorphine free base. Corresponding depot compositions and methods of treatment in pain management, by opioid maintenance and related methods are provided.
US09937163B2 Remedy for psychoneurotic diseases
A medicinal preparation for preventing and/or treating psychoneurotic diseases such as integration dysfunction and Alzheimer's disease which contains tropisetron or its pharmaceutically acceptable salt as the active ingredient.
US09937162B2 Methods of treating and preventing vascular instability diseases
Methods are provided of treating and preventing stroke diseases, such as cerebral cavernous malformation, by the administration of tempol and/or cholecalciferol.
US09937161B2 Combinatorial compositions and methods for treatment of melanoma
Embodiments described here are combinatorial compositions and methods using these compositions for treating melanomas having activated mutations. The compositions comprises combinations of inhibitors of a MAPK pathway, ERK inhibitors, EGFR inhibitors, oxidative phosphorylation (OXPHOS) inhibitors, inhibitors of B-Raf, mitochondrial inhibitors, c-KIT inhibitors, MEK inhibitors and tigecycline or a derivative thereof.
US09937155B2 Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
US09937153B2 Oral pharmaceutical formulation of omarigliptin
The present invention is directed to stable, oral pharmaceutical formulations of dipeptidyl peptidase-4 inhibitors, such as omarigliptin. Such pharmaceutical formulations comprise omarigliptin; and neutral excipients, wherein the neutral excipient is present in the amount of at least 75% by weight of the pharmaceutical formulation and comprises at least one non-reducible sugar diluent or a mixture of non-reducible sugar diluents.
US09937150B2 Method for enhancing the oxygenation level of tissue cells as an alternative method for hyperbaric oxygen therapy
The present invention relates to a method for substituting for or acting with the hyperbaric oxygen therapy to improve hypoxia, comprising the step of: administrating a phthalide compound to a subject in need thereof, wherein the phthalide compound can increase the oxygen release efficiency of blood hemoglobin (Hb) in the subject and further increase the cellular oxygenation level, and when the phthalide compound substitutes for or act with the hyperbaric oxygen therapy, the common adverse side effects of the hyperbaric oxygen therapy, such as barotrauma, decompression sickness and oxygen poisoning, are prevented. The phthalide compound is used to substitute for or act with 2,3-BPG, to modulate and decrease the oxygen affinity of hemoglobin (Hb), to increase the oxygen release efficiency of hemoglobin (Hb) to tissue cells, thereby achieving a normal cellular oxygenation level and maintaining the cellular oxygenation level in a normal range.
US09937146B2 Enkephalin-influencing composition and method
A composition which includes Phenylalanine, Serine, Glutamine and GABA (γ-aminobutyric acid). The composition contains the essential amino acids Phenylalanine; Glutamine; the non-essential amino acid Serine; and GABA (γ-aminobutyric acid) in concentrations effective to influence or modulate the neurotransmitter pentapeptide enkephalin. The composition may further comprise tetrahydrocannabinol (THC).
US09937141B2 Carcinoma diagnosis and treatment, based on ODC1 genotype
The present invention provides methods and kits a) for predicting colorectal cancer patient survival, as well as the survival of patients harboring other invasive cancers where cellular proliferation and carcinogenesis is linked, in part, to high levels of ODC activity and increased cellular polyamine contents, and b) for selecting the corresponding treatment options for such patients based on the allelic nucleotide sequence or SNP at position +316 of the ODC1 promoter gene as well as cancer treatment methods, in each case, which include the determination of the ODC1 promoter +316 position genotype, as a means to guide treatment selection.
US09937140B2 Branched chain amino acids: formulations and methods of treatment
The present disclosure includes a formulation of branched chain amino acids and arginine for treatment of diseases for which the pathological mechanism includes autophagy. The formulation includes defined ratios of the branched chain amino acids Isoleucine, Leucine, and Valine along with Arginine. These disease indications include congestive heart failure, myocardial infarction, and ischemia reperfusion injury. Diseases of other organs that involve autophagy are also disclosed. Additionally, methods of using the disclosed formulation to treat these disease indications are provided. The disclosure also describes a kit that includes a lyophilized form of the formulation, a solvent for reconstitution, and instructions directing reconstitution.
US09937138B2 Enhancer of survival of transplanted organ
The present invention provides an agent for promoting graft survival which can suppress rejection without use of existing immunosuppressants, an organ preservation solution capable of maintaining the freshness of an organ excised from a donor, and the like. An agent for promoting graft survival or an organ preservation solution is prepared, which comprises 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt of ALA or the derivative and an iron compound as active ingredients. Preferable examples of the ALAs can include ALA and various esters such as methyl ester, ethyl ester, propyl ester, butyl ester, and pentyl ester of ALA, and their hydrochlorides, phosphates, and sulfates. Preferable examples of the iron compound can include sodium ferrous citrate.
US09937129B2 Materials and methods for delivering compositions to selected tissues
This invention relates to devices, systems and methods for delivering preprogrammed quantities of an active ingredient to a biological system over time without the need for external power or electronics.
US09937123B2 Rapidly disintegrating films for delivery of pharmaceutical or cosmetic agents
A dissolvable film for delivering a pharmaceutical agent comprises a first water soluble polymer in an amount of from 2 to 35 weight percent and having a molecular weight from about 5,000 daltons to about 49,000 daltons; a second water soluble polymer in an amount of from 2 to 35 weight percent and having a molecular weight greater than 60,000 daltons; and a pharmaceutically active ingredient. The film has a thickness of about 20 microns to about 1200 microns and is configured to disintegrate after contact with a mucous membrane and thereby release the active ingredient.
US09937120B2 Polyelectrolyte dental adhesives for whitening teeth and teeth components
This document relates to methods and materials involved in providing a tooth, tooth component, or inorganic dental material (e.g., a human tooth, a human tooth component, or an inorganic dental material within a human's mouth) with a white appearance. For example, a whitening adhesive containing a conjugate of at least a polyamine, a polyphosphate, and one or more whitening agents (e.g., titanium dioxide, zinc oxide, and/or hydroxyapatite) can be used to provide a tooth, tooth component, or inorganic dental material with a whiter appearance.
US09937116B2 Oral care whitening compositions
Described herein are oral care compositions comprising a whitening agent having the formula: R1—O—O—R2; and an aliphatic ketone; wherein R1 and R2 are independently selected from hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 carbonyl, SO3, and phenyl; and methods of making and using the same.
US09937113B2 Antiperspirant compositions
A solid stick antiperspirant composition is provided. The antiperspirant composition includes aluminum zirconium tetrachlorohydrex glycine having a concentration from about 10% to about 35% by weight of the composition, an anhydrous liquid carrier, one or more structurants having a concentration from about 15% to about 25% by weight of the composition, wherein the one or more structurants comprises one or more waxes and a non-ionic exthoxylated linear alcohol having a carbon chain length from about 20 to about 40. The solid stick antiperspirant composition is a single phase.
US09937110B2 Translucent gel system
The present invention concerns a translucent gel system, notably a hair conditioner gel, comprising at least a carboxylic acid, an alkoxylated alkyl or alkenyl amine and a cationic surfactant. Such a translucent gel system provides an excellent conditioning effect for washing skin and/or hair and a high transmittance.
US09937109B2 Encapsulated benefit agents
A particle comprising:—(a) a spacer which is a polyethylene glycol (PEG) chain with molecular weight Mw (and therefore the required length) of the spacer extending from the particle from 3000 to 400,000; (b) a deposition aid; and (c) a benefit agent, wherein the spacer is attached directly to the particle and the deposition aid is attached to the end of the spacer.
US09937108B2 Wet wiper articles and methods for cleaning removable dental appliances
A wet wiper for cleaning accumulated oral debris from removable dental appliances. The wet wiper comprises a water insoluble substrate and a physiologically acceptable cleansing composition, wherein the cleansing composition comprises: (i) a liquid carrier consisting of a solution of water and ethyl alcohol, wherein the ethyl alcohol is about 3% to about 90% by weight of the cleansing composition, and wherein the water is q.s. to 100%; and (ii) about 0.001% to about 5% by weight of the cleansing composition of a flavor. Methods for cleaning removable dental appliances are also provided, such methods comprising the step of contacting, for a time sufficient to reduce oral debris, the removable dental appliances, with a wet wiper of the present invention.
US09937107B2 Fluoroaluminosilicate glass powder
Provided is a fluoroaluminosilicate glass powder that can provide a dental glass ionomer cement hardened body excellent in acid resistance, the glass powder including sodium and potassium which have an effect of lowering the reflective index of glass. A mass ratio of potassium to sodium in the component is in the range of from 1.2 to 1.9 in terms of oxide.
US09937106B2 Kit of parts, method of producing and use thereof
The invention relates to a kit of parts comprising part A and part B, part A comprising a polymerizable component having an acid group in the molecule, an initiator, part B comprising an activator, and a film former with a molecular weight of at least 1000.The invention also relates to a composition obtainable by mixing the components contained in the kit of parts and to a process for producing the kit of parts comprising the steps of bringing the components contained in part B of the kit in contact with a surface, drying the surface to form a film.
US09937104B2 Nanostructured antibacterial and remineralizing dental bonding agents and dental bonding systems
The present invention provides dental bonding agents and dental bonding systems comprising the dental bonding agents. The dental bonding agents of the invention are characterized by having antibacterial properties, and in some aspects of the invention, remineralizing properties.
US09937103B1 Emesis receptacle
The emesis receptacle is a container that is adapted for use in receiving and storing discharge of emesis. The emesis receptacle is designed to receive the discharge with a minimum of spillage. The emesis receptacle further provides storage areas for the purpose of containing domestic articles necessary for maintaining comfort and cleanliness throughout the discharge process. The emesis receptacle comprises a hollow container, a plurality of handles, one or more pockets, a drawer, a false bottom, and a chin extension. The plurality of handles, the chin extension, and the one or more pockets are attached to the container. The drawer is installed within the container. The false bottom is positioned within the container such that the false bottom protects the contents of the drawer from the discharge of emesis.
US09937097B2 Stimulation device having an appendage
A stimulation device is provided in accordance with one embodiment. The stimulation device includes a chamber which has a flexible wall portion. A drive unit of the stimulation device is in physical communication with the flexible wall portion so as to cause deflections of the flexible wall portion in opposing directions, thereby resulting in a changing volume of the chamber. The changing volume of the chamber results in modulated positive and negative pressures with respect to a reference pressure. An opening of the stimulation device is for applying the modulated positive and negative pressures to a body part. An appendage of the stimulation device may be used as a handle to allow a user to position the stimulation device over the body part. The stimulation device includes a control device for controlling the drive unit.
US09937095B2 Exercise training apparatus
An exercise training apparatus attached to a trainee who performs a body exercise training, includes movable bodies, actuators, sensors and a processor. The movable bodies each having a fixed member which a part of a trainee's body is fixed to and exercising a trainee's extremities by rotating around shafts, respectively. The sensors each detecting a physical quantity that changes depending on force applied to the fixed members by a trainee. The processor, in response to a detection of a predetermined change in a physical quantity by the sensors, driving the actuators, rotating the movable bodies in a first direction and successively rotating the movable bodies in a second direction opposite to the first direction.
US09937089B2 Sliding arm mechanism for wheelchairs
A sliding arm mechanism for attaching to an arm of a wheelchair is provided herein. One concept of the present disclosure is directed to a sliding arm mechanism that includes a main portion having a top area, a bottom area, first and second opposing end areas, first and second opposing side areas and an inner cavity. The sliding arm mechanism also includes a slide rail, comprising a top side, a bottom side and an elongated aperture located between the top side and the bottom side, which is adapted to be housed within the inner cavity of the main portion. The bottom side of the slide rail is removably coupled to a top part of the arm of the wheelchair. The slide rail and the main portion are slidably coupled to allow the main portion to move laterally over the slide rail in a direction parallel to the top part of the arm of the wheelchair, thus allowing the main portion to move between a first position and a second position. In some embodiments, the first position corresponds to a full-length position and the second position corresponds to a desk-length position, such that a user can adjust the sliding arm mechanism to be able to access a desk or table.
US09937088B2 Automotive wheelchair storage device
An automatic device for storing wheelchairs behind vehicles is provided. The wheelchair storage device is configured to mount to the exterior of a vehicle on the vehicle's roof rack. The storage device includes a horizontal and vertical arm, that when activated by a motor, uses a series of motors and gears to move a wheelchair attached to the vertical arm to the rear of the vehicle. A storage platform is further provided that receives and secures the wheelchair behind the vehicle. The motors of the storage device may be powered by the vehicle's engine, and a remote may be provided for user control.
US09937085B2 Absorbent article having fluid flow control member
An absorbent article, the absorbent article being a personal hygiene article, includes a liquid permeable top sheet, a liquid impermeable back sheet, an absorbent core enclosed between the top sheet and the back sheet, and a fluid flow control member arranged between the top sheet and the backsheet. The fluid flow control member is a spacer fabric including a top layer, a bottom layer and an interconnecting layer of pile filaments between the top layer and the bottom layer. The spacer fabric has a ratio of thickness to basis weight at 15 kPa of at least 1.5·10−5 m/gsm, as measured according to the Mecano-method disclosed herein.
US09937078B2 Laser methods for creating an antioxidant sink in the crystalline lens for the maintenance of eye health and physiology and slowing presbyopia development
Systems and methods of laser treatment of the intact crystalline lens to increase ionic transport of antioxidants in specific areas where flexural changes and transparency reduction come from lens aging. Microchannels created in patterns and grids placed strategically in the inner lens carry antioxidants from the source—the anterior and the epithelium—into areas scarce or void of transport mechanisms (and thus scarce of antioxidants). A variety of patterns are utilized to facilitate ions traveling along new pathways.
US09937075B2 Apparatus and methods for ocular injection
An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
US09937069B2 Pusher guide wire and delivery system comprising the same
A pusher guide wire and a delivery system can smoothly pass through the inside of even a curved blood vessel without causing excessive burden to a stent, a catheter, and the like. A pusher guide wire has a tubular member capable of moving in a radial direction relative to a core shaft of the pusher guide wire. When the pusher guide wire is used together with a stent in a delivery system, the tubular member makes contact with the stent in an appropriate manner when passing through the inside of a curved blood vessel. The stent may include a proximal end engagement portion provided at a proximal end of the stent. When the stent is placed so that the proximal end engagement portion engages with the pusher guide wire, the stent can be pulled back inside the catheter by pulling the pusher guide wire in the proximal direction.
US09937067B2 Telescoping ureteral stent
An indwelling stent is provided. The stent includes a distal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, and a proximal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, wherein the distal member and the proximal member collectively define the stent, and wherein the distal and proximal members are discrete components and are telescopingly arranged with the distal end portion of the proximal member extending over an outer surface of the distal member.
US09937064B2 Osseointegrated neural interface and method
An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a second end operatively connected to the prosthetic and an inner surface defining a cavity. An electrode is receiveable on a terminal end of a peripheral nerve and positionable within the cavity of the rod. The electrode being capable of sensing the neural signals generated by the peripheral nerve and stimulating the peripheral nerve. A recording/stimulation unit, receiveable within the cavity of the rod, records the neural signals from the peripheral nerve sensed by the electrode and transmits the signals to a controller operatively connected thereto. The controller controls operation of the prosthetic in response to the neural signals recorded by the recording unit. In addition, the controller receives stimulation signals from a sensor in the prosthetic and causes the electrode to stimulate the peripheral nerve via the recording/stimulation unit in response thereto.
US09937063B2 Trialing for prosthetic component
An orthopedic system according to one embodiment of the disclosure comprises a first trial member capable of forming a broach cavity in a first bone of a patient. A second trial member is removeably coupleable to the first trial member in a fixed alignment with respect to the trial member. An alignment member is removeably coupleable in a fixed alignment with respect to the first trial member. The alignment member comprises indicia configured to provide for alignment of the alignment member with respect to at least one of the first bone and a second bone of the patient. The alignment of the second trial member with respect to the first trial member when coupled to the first trial member corresponds to the alignment of the alignment member with respect to the first trial member when coupled with the first trial member.
US09937062B2 Device and method for enabling an orthopedic tool for parameter measurement
A system for enabling and disabling a medical device. The system includes a cradle having a magnet for generating a magnetic field. The cradle supports and aligns the medical device in a predetermined orientation. Medical device placed in the cradle exposes a magnetic sensitive switch to the magnetic field of the magnet that produces a change in state of the magnetic sensitive switch. Medical device further includes a switch, indicator, logic circuitry, delay circuit, and detect circuit for coupling a power source to electronic circuitry. In a first mode of operation the medical device can be turned on and then turned off. In a second mode of operation the medical device cannot be turned off after being turned on.
US09937058B2 Prosthetic implant and method of implantation
A prosthetic implant useful in a cementless application is disclosed. The implant may include a curved bone facing surface and one or more pegs or keels. Preferably, the implant is implanted on a bone surface that has been prepared so as to allow for a snap fit between the implant and the bone.
US09937056B2 Bone stabilization member with bone screw retention mechanism
A spinal implant for stabilizing first and second vertebrae. The spinal implant includes an intervertebral spacer and a bone stabilization member configured to be coupled to the intervertebral spacer. The bone stabilization member includes a plurality of bone screw openings and a plurality of bone screws extendable through the bone screw openings to secure the bone stabilization member to the vertebrae. A retention member, which is slidably coupled to the bone stabilization member, is linearly slidable between a first position and a second position while coupled to the bone stabilization member. In the first position, each of the bone screws is permitted to be inserted into the bone screw openings, and in the second position the retention member at least partially covers each of the bone screw openings to prevent a bone screw from backing out of the respective bone screw opening.
US09937055B1 Scoring implant trial and implant inserter for spinal fusion system
A system for fusing together opposing vertebra of a spine that defines a disc space therebetween. The system comprises a disc preparation instrument and an inserter assembly for use in the interbody fusion procedure. Disc preparation instrument comprises an elongate handle supporting a trial device at one end thereof. Inserter assembly comprises an elongate inserter supporting at one end thereof an interbody cage implant for insertion into the disc space. Disc preparation instrument provides a scoring element that scribes vertebral endplates at an appropriate scored location for anchor blades on the cage implant to engage the vertebral bodies. Inserter is used to introduce cage implant with anchor blades into the disc space to an appropriate depth so that the blades will be precisely positioned at the scored location created by the scoring element for penetration into the vertebral endplates.
US09937048B2 Femoral stem including an anchor to facilitate assembly and implantation
An orthopedic prosthesis for use in a hip replacement surgery. The orthopedic prosthesis includes an elongated stem component that has a proximal body, a neck extending superiorly and medially from the proximal body and a tapered stem extending inferiorly from the proximal body. An anchor is positioned on the neck and is configured to be engaged by a surgical instrument. A system for use in assembling the orthopedic prosthesis and a method of assembly are also disclosed.
US09937047B2 Spacer mold for orthopedic implants
A mold for forming a prosthesis is disclosed. The mold can include a stem portion, a head portion, and a securement assembly. The stem portion and the head portion can be provided in a kit having a variety of different interior dimensions so that a user can select or customize a mold cavity size based on the dimensions of a particular implant site of a patient. While a set of stem portions and head portions can have interior dimensions of varying sizes, each of the stem portions and each of the head portions can have the same or similar exterior dimensions for attachment using a common securement structure. Related methods are also disclosed.
US09937044B2 Percutaneous valve repair by reshaping and resizing right ventricle
The present teachings provide devices and methods of treating a tricuspid valve regurgitation. Specifically, one aspect of the present teachings provides devices and methods for reshaping and resizing the right ventricle by reducing the distances between two papillary muscles. Another aspect of the present teachings provides devices and methods for reshaping and resizing the right ventricle by reducing the distances along the right ventricle wall. Another aspect of the present teachings provides devices and methods for reshaping and resizing the right ventricle by reducing the distance between the distance of right ventricle outflow track and the right ventricle wall. Another aspect of the present teachings provides devices and methods for reshaping and resizing the right ventricle by changing the right ventricle sphericity index. Another aspect of the present teachings provides devices and methods for reshaping and resizing the right ventricle by reducing the tricuspid valve tethering height.
US09937040B2 Method of repairing an aortic valve
A method comprises implanting an aortic ring externally on the outer surface and around the aortic root to form a closed-perimeter flexible structure only around the subvalvular region externally of the aortic root, generally adjacent the nadir portion of the valve annulus and below the attachment points of the coronary arteries; and constraining the aortic root with the closed-perimeter structure to an anatomically representative geometry that improves coaptation of the leaflet free margins in the diastolic phase of the cardiac cycle.