Document Document Title
US09745636B2 SWI5 gene as a diagnostic target for the identification of fungal and yeast species
The invention relates to the SWI5 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate between fungal and yeast species.
US09745635B2 Recurrent gene fusions in prostate cancer
Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
US09745630B2 MiRNA fingerprint in the diagnosis of prostate cancer
MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing prostate cancer based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
US09745629B2 In vitro method for screening for candidate compounds for preventing and/or attenuating ageing of the skin, and/or for hydrating the skin
The identification and the use of compounds which activate the expression of at least one gene selected from LARGE, HS6ST2 and ST8SIA1 is provided. An in vitro method for screening for candidate compounds includes: (a) bringing at least one test compound in contact with a sample of keratinocytes in vitro; (b) measuring the expression of at least one gene selected from LARGE, HS6ST2 and ST8SIA1, in the keratinocytes; and (c) selecting the compounds for which an activation of at least 1.4 fold of the expression of at least one of the LARGE, HS6ST2 and ST8SIA1 genes is measured in the keratinocytes treated in (a) compared with the untreated keratinocytes. The candidate compounds may be useful for preventing and/or attenuating ageing, and/or for hydrating skin.
US09745621B2 Temperature gradient surface plasmon resonance instrument
A system and method for sensitive measurements of molecular binding as a function of time and temperature provided by a surface plasmon resonance (SPR) instrument producing a stable temperature gradient over the sensor surface. Continuous monitoring of reflected light intensity from different locations of the sensor allows simultaneous measurement of time and temperature dependence of binding interactions.
US09745619B2 Process for detecting or quantifying nucleic acids in a library
This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.
US09745618B2 Photoblocked probes and methods for sequential detection of nucleic acids
Photoblocked probes are disclosed including a specific hydrolysis probe having a first nucleic acid sequence complementary to a target having a second nucleic acid sequence, a first and a second interactive labels, a 5′ end and a 3′ end, and one or more photocleavable moieties coupled to one or more nucleotides of the specific hydrolysis probe, wherein the photocleaveable moiety interferes with the hybridization of the specific hydrolysis probe with the region of the amplification product. Also disclosed are PCR methods for the detection of the presence or absence of a target nucleic acid in a sample utilizing the photoblocked probes, as well as kits.
US09745614B2 Reduced representation bisulfite sequencing with diversity adaptors
Described herein are methods, compositions and kits for the generation of bisulfite-converted libraries useful for conducting reduced representation bisulfite sequencing (RRBS). The methods described herein can be employed to generate RRBS libraries in a manner that is easier and more cost-efficient than conventional RRBS methods, and can be efficiently sequenced with next generation sequencing (NGS) techniques without the need for genomic, higher diversity sequencing controls such as PhiX spike-ins.
US09745608B2 Processes and recombinant microorganisms for the production of cadaverine
Recombinant microorganisms comprising DNA molecules in a deregulated form which improve the production of cadaverine or N-acetylcadaverine, as well as recombinant DNA molecules and polypeptides used to produce the microorganisms are provided. Said microorganisms comprise an intracellular lysine decarboxylase activity and a deregulated cadaverine export activity, or comprise a decreased cadaverine export activity and an enhanced N-acetylcadaverine forming activity. Processes for the production of cadaverine N-acetylcadaverine using the recombinant microorganisms are also provided.
US09745604B2 Processing biomass
Biomass (e.g., plant biomass, animal biomass, microbial, and municipal waste biomass) is processed to produce useful products, such as food products and amino acids.
US09745600B2 Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides
The present specification discloses engineered Type II CRISPR-Cas9 systems comprising split-nexus Cas9-associated polynucleotides (sn-casPNs), including systems comprising three split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN/sn3-casPN) and systems comprising two split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN). Together with a Cas9 protein, the sn-casPNs facilitate site-specific modifications, including cleavage and mutagenesis, of a target polynucleotide in vitro and in vivo. Furthermore, the engineered Type II CRISPR-Cas9 systems comprising sn-casPNs are useful in methods of regulating expression of a target nucleic acid. Methods are described herein for the creation of a variety of engineered Type II CRISPR-Cas9 systems comprising two or more sn-casPNs. Polynucleotide sequences, expression cassettes, vectors, compositions, and kits for carrying out a variety of methods are also described. Furthermore, the present specification provides genetically modified cells, compositions of modified cells, transgenic organisms, pharmaceutical compositions, as well as a variety of compositions and methods involving the engineered Type II CRISPR-Cas9 systems.
US09745598B2 miRNA-regulated differentiation-dependent self-deleting cassette
Targeting constructs and methods of using them are provided for differentiation-dependent modification of nucleic acid sequences in cells and in non-human animals. Targeting constructs comprising a promoter operably linked to a recombinase are provided, wherein the promoter drives transcription of the recombinase in an differentiated cell but not an undifferentiated cell. Promoters include Blimp1, Prm1, Gata6, Gata4, Igf2, Lhx2, Lhx5, and Pax3. Targeting constructs with a cassette flanked on both sides by recombinase sites can be removed using a recombinase gene operably linked to a 3′-UTR that comprises a recognition site for an miRNA that is transcribed in undifferentiated cells but not in differentiated cells. The constructs may be included in targeting vectors, and can be used to automatically modify or excise a selection cassette from an ES cell, a non-human embryo, or a non-human animal.
US09745596B2 Identification and use of KRP mutants in wheat
The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.
US09745595B2 Methods of increasing biomass and/or growth rate of a plant under non-stress conditions
Provided are methods of increasing yield, biomass, growth rate, vigor, and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence at least 80% identical to SEQ ID NO: 908 or 71; or an exogenous polynucleotide encoding a polypeptide at least 80% identical to SEQ ID NO: 176.
US09745591B2 Plants having altered expression and activity of yield-related proteins
Transgenic plants that have enhanced yield-related traits, such as increased seed oil production, are produced by genetically engineering the plants to down-regulate the expression of at least one BPM protein. Such transgenic plants can, for example, be cultivated and yield higher seed oil production than control plants which have not been genetically engineered for down regulation of a BPM protein.
US09745590B2 Circular nucleic acid vectors, and methods for making and using the same
Circular nucleic acid vectors that provide for persistently high levels of protein expression are provided. The circular vectors of the subject invention are characterized by being devoid of expression-silencing bacterial sequences, where in many embodiments the subject vectors include a unidirectional site-specific recombination product hybrid sequence in addition to an expression cassette. Also provided are methods of using the subject vectors for introduction of a nucleic acid, e.g., an expression cassette, into a target cell, as well as preparations for use in practicing such methods. The subject methods and compositions find use in a variety of different applications, including both research and therapeutic applications. Also provided is a highly efficient and readily scalable method for producing the vectors employed in the subject methods, as well as reagents and kits/systems for practicing the same.
US09745588B2 Transcription terminator sequences
The present invention provides new transcription termination signal sequences, especially a polynucleotide comprising at least two consecutive transcription termination signals, characterized in that consecutive transcription termination signals comprise at least a first and a second transcription termination signal that are at most 1000 nucleotides apart, and at least one of the termination signal has or encodes a RNA hairpin structure.
US09745583B2 Liposome for topical administration and application thereof
This invention provides a novel delivery means that enables efficient delivery of an active ingredient to a target cell. Such novel delivery means is a liposome for topical administration that consists of dioleylphosphatidylethanolamine (DOPE), phosphatidylcholine, and cationic lipid, that is not modified with PEG, and that is free of cholesterol.
US09745581B2 Methods of treating and diagnosing diseases using agents that regulate the alternative splicing pathway
A method of determining a treatment for an inflammatory disorder in a subject, is disclosed. The method comprises determining an amount of SRSF6 in a sample from the subject, wherein an amount of the SRSF6 is indicative of the treatment. Methods of diagnosing inflammatory disorders and treating same are also disclosed.
US09745580B2 Treatment of fibroblast growth factor 21 (FGF21) related diseases by inhibition of natural antisense transcript to FGF21
The present invention relates to antisense of oligonucleotides that modulate the expression of and/or function of Fibroblast growth factor 21 (FGF21), in particular, by targeting natural antisense polynucleotides of Fibroblast growth factor 21 (FGF21). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of FGF21.
US09745576B2 RNA modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders
The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
US09745570B2 Methods, compositions, and kits for generating rRNA-depleted samples or isolating rRNA from samples
The present invention provides methods, compositions, and kits for generating rRNA-depleted samples and for isolating rRNA from samples. In particular, the present invention provides compositions comprising affinity-tagged antisense rRNA molecules corresponding to substantially all of at least one rRNA molecule (e.g., 28S, 26S, 25S, 18S, 5.8S and 5S eukaryotic cytoplasmic rRNA molecules, 12S and 16S eukaryotic mitochondrial rRNA molecules, and 23S, 16S and 5S prokaryotic rRNA molecules) and methods for using such compositions to generate rRNA-depleted samples or to isolate rRNA molecules from samples.
US09745569B2 System for generating high concentration factors for low cell density suspensions
Acoustophoretic devices and methods for concentrating targeted biological cells in a reduced volume using multi-dimensional acoustic standing waves are disclosed. The methods include flowing a mixture of a host fluid and the biological cells through an acoustophoretic device. The acoustophoretic devices include an inlet, an outlet, and a flow chamber having an ultrasonic transducer-reflector pair. Biological cells, such as T cells, are separated from a host fluid for utilization in allergenic or autologous cell therapies. The disclosed devices and methods are capable of concentrating biological cells to at least 100 times their original cell concentration. The disclosed methods and devices are further capable of decreasing an original feed volume to a final concentrated volume that is less than one percent of the original feed volume.
US09745567B2 Compositions and methods for treating multiple sclerosis
Provided are electrokinetically-altered fluids (gas-enriched electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for use in treating inflammatory neurodegenerative condition or disease or at least one symptom thereof. The electrokinetically-altered fluids or therapeutic compositions and methods include electrokinetically-altered ioinic aqueous fluids optionally in combination with other therapeutic agents. Particular aspects provide for regulating or modulating intracellular signal transduction associated with said inflammatory responses by modulation of at least one of cellular membranes, membrane potential, membrane proteins such as membrane receptors, including but not limited to G-Protein Coupled Receptors (GPCR), and intercellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes). Other embodiments include particular routes of administration or formulations for the electrokinetically-altered fluids (e.g., electrokinetically-altered gas-enriched fluids and solutions) and therapeutic compositions.
US09745566B2 Recombinant microorganisms and methods of use thereof
The present provides selection markers, methods, nucleic acids, and vectors of use in the preparation of recombinant Clostridium spp.
US09745565B2 Treatment of gluten intolerance and related conditions
Provided herein are compositions, foods comprising nepenthesin or a derivative thereof and methods of using nepenthesin or a derivative thereof for modulating gluten intolerance and related conditions, such as celiac disease.
US09745563B2 Amylase-deficient strain
The present invention relates to a mutant microbial host cell which has been modified, preferably in its genome, to result in a deficiency in the production of a polypeptide having α-amylase activity AmyC or an homologous thereof. It has been surprisingly found that when the mutant microbial host cell according to the invention is used in a method to produce a compound of interest, for example an enzyme, an improved purity of the product is obtained.
US09745558B2 VEGFR-3 ligand binding molecules and uses thereof
The present invention is directed to VEGFR-3 ligand binding molecules and uses thereof to modulate angiogenesis and/or lymphangiogenesis. A glycosylation sequon of wildtype VEGFR-3 has been modified to eliminate glycosylation in the ligand binding molecules.
US09745556B2 Variants of glycerol dehydrogenase having D-lactate dehydrogenase activity and uses thereof
The present invention provides methods of designing and generating glycerol dehydrogenase (GlyDH) variants that have altered function as compared to a parent polypeptide. The present invention further provides nucleic acids encoding GlyDH polypeptide variants having altered function as compared to the parent polypeptide. Host cells comprising polynucleotides encoding GlyDH variants and methods of producing lactic acids are also provided in various aspects of the invention.
US09745552B2 Anti CD4 antibodies to prevent in particular graft-versus-host-disease (GvHD)
The present invention relates to, among others, an in vitro method of modifying a cell graft containing immune cells comprising the steps of incubating a cell graft containing immune cells with an anti CD4 antibody wherein said incubating is carried out for from 1 minute to 7 days, b) removing unbound antibody from said graft; as well as to corresponding modified grafts and uses. The invention further relates to the modification of antibodies reactive to the CD4 human leukocyte antigen to provide anti-CD4 antibodies that have a reduced number of potential T-cell epitopes but retain the ability to bind to CD4, such as to an anti human CD4-antibody comprising a heavy chain immunoglobulin variable domain (VH) and a light chain immunoglobulin variable domain (VL), wherein at least one T cell epitope located outside the CDRs of said immunoglobulin variable domains is removed from said immunoglobulin variable domains. Preferably, the specificity and mode of action of the anti-CD4 antibodies are not affected by the modification(s).
US09745551B2 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
The present invention relates to methods of generating and expanding hitman embryonic stem eel! derived mesenchymal-like stem/siromal cells. These hES-MSCs are characterized at least in part by the low level of expression of IL-6. These cells are useful for the prevention and treatment of T cell related autoimmune disease, especially multiple sclerosis, as well as for delivering agents across the blood-brain barrier and the blood-spinal cord barrier. Also provided is a method of selecting clinical grade hES-MSC and a method of modifying MSC to produced a MSC with specific biomarker profile. The modified MSC are useful for treatment of various diseases.
US09745550B2 Synthetic surfaces for culturing stem cell derived cardiomyocytes
Synthetic surfaces suitable for culturing stem cell derived cardiomyocytes contain acrylate polymers formed from one or more acrylate monomers. The acrylate surfaces, in many cases, are suitable for culturing stem cell derived cardiomyocytes in chemically defined media.
US09745548B2 Acoustic perfusion devices
Methods are disclosed for separating beads and cells from a host fluid. The method includes flowing a mixture containing the host fluid, the beads, and the cells through an acoustophoretic device having an ultrasonic transducer including a piezoelectric material driven by a drive signal to create a multi-dimensional acoustic standing wave. A drive signal is sent to drive the at least one ultrasonic transducer to create the multi-dimensional acoustic standing wave. A recirculating fluid stream having a tangential flow path is located substantially tangential to the standing wave and separated therefrom by an interface region. A portion of the cells pass through the standing wave, and the beads are held back from the standing wave in the recirculating fluid stream at the interface region. Also disclosed is an acoustophoretic device having a coolant inlet adapted to permit the ingress of a cooling fluid into the device for cooling the transducer.
US09745546B2 Cassette for sterility testing
The invention provides a device for growing cells—referred to as a cassette. The cell culturing device includes a housing that contains a lid having an optically clear window; a fluid distribution channel; a sample injection port fluidically connected to the fluid distribution channel; a base housing a porous media pad; and a media injection port fluidically connected to the media pad. The lid mates to the base to form a sterile seal; the fluid distribution channel is disposed over the media pad, which is viewable through the optical window; and sample fluid introduced into the fluid distribution channel is distributed evenly to the media pad, e.g., via a plurality of channels. The invention also provides kits that include cassettes of the invention and a tube set.
US09745545B2 Faster aging of alcoholic beverages
Aging of alcoholic beverages is expedited by increasing the exposed surface area of wood by introducing multiple wooden surfaces, improving mixing by reducing the spacing between wooden surfaces, maintaining the temperature of alcoholic beverage to optimal level and reducing the cost or production by working with larger volumes at a time.
US09745543B2 Stable liquid manual dishwashing compositions containing enzymes
Liquid stable enzyme compositions and methods of employing the same for cleaning, including warewashing and dishwashing, are disclosed. The stable enzyme compositions preferably employ an amphoteric surfactant stabilizing agent, such as disodium camphodiacetate (CADA), to stabilize a mixture of traditionally unstable enzymes, such as proteases and lipases.
US09745542B2 Burner cup
A device has a canister with a bulk wick occupying at least most of the canister, and a lid affixed to the canister and in contact with the bulk wick. The lid defines an opening exposing a portion of the bulk wick for lighting.
US09745537B2 Process for the extraction of lipids from algal biomass
A process for the extraction of lipids from algal biomass comprising: —producing an aqueous suspension of algal biomass; —adding to said aqueous suspension of algal biomass at least one organic solvent immiscible or substantially immiscible with water obtaining an organic-aqueous mixture; —subjecting said organic-aqueous mixture to evaporation of water and lipid extraction, operating at a temperature such to obtain the substantial complete removal of the water from said organic-aqueous mixture, obtaining: (i) an organic phase comprising lipids and said organic solvent; (ii) a semi-solid phase comprising a residue of said algal biomass.
US09745524B2 Process for the production of a gasoline with a low sulfur content
This invention relates to a process for treatment of a gasoline that comprises diolefins, olefins and sulfur-containing compounds including mercaptans, consisting of a stage for treatment of the gasoline in a distillation column (2) comprising at least one reaction zone (3) including at least one catalyst that makes it possible to carry out the addition of mercaptans to the olefins that are contained in the gasoline that distills toward the top of the catalytic column.
US09745522B2 Method of obtaining paraffinic hydrocarbons from natural fat
A method of obtaining paraffinic hydrocarbons from fat, by an exemplary method, whereby the method is performed in two stages, in a coupled flow-type system, under atmospheric pressure conditions, in the presence of heterogeneous catalysts, after their thermal activation, so that in Stage I the fat and/or waste fat is heated at a temperature range of 100-500° C., in the presence of an inert gas, in the presence of a catalyst in the form of a metal oxide on an oxide support or in the form of a mixture of at least two metal oxides on an oxide support. The product obtained in Stage I is treated, in the presence of an inert gas, at a temperature range of 100-500° C., in the presence of a metallic catalyst on an oxide support, with hydrogen gas or with a mixture of hydrogen and carbon monoxide, obtained in the selective decomposition of methanol.
US09745520B2 System for purifying crude oils
The invention relates to removing contaminants from oil using solid sorbents that are comprised primarily of carbon and preferably of coke particles. The coke particles have an affinity for contaminants in oil and are sized to be filtered from oil without plugging. Most contaminants have such a small size that they tend to plug up filters. As the contaminants agglomerate onto the solid sorbent, the resulting particles form a filter cake on conventional filter materials in such a way as to allow the oil to pass on through without significant pressure drop or delay.
US09745518B2 Processing hydrocarbon-containing materials
Methods are provided for enhancing oxidative molecular weight reduction in a hydrocarbon-containing material. For example, some methods include (a) providing a first hydrocarbon-containing material comprising a first hydrocarbon, said first hydrocarbon-containing material having been exposed to irradiation from a beam of particles, the beam of particles imparting one or more functional groups to said first hydrocarbon containing material; and (b) oxidizing the first hydrocarbon-containing material with one or more oxidants in the presence of one or more compounds comprising one or more naturally-occurring, non-radioactive group 5, 6, 8, 9, 10 or 11 elements, the one or more elements participating in a Fenton-type reaction while oxidizing, to produce a second hydrocarbon-containing material comprising a second hydrocarbon, the second hydrocarbon having a molecular weight lower than that of the first hydrocarbon, the functional groups enhancing the effectiveness of the oxidizing reaction.
US09745515B2 Fire resistant material
The present invention relates to inorganic-organic hybrids (IOHs), methods for their preparation and their use as fire resistant materials or components of fire resistant materials. More specifically, the invention relates to polyamide fire resistant formulations containing IOHs which have application in the production of fire resistant articles or parts thereof for use in the transportation, building, construction and electrical or optical industries.
US09745514B2 Photo-alignment composition and method of manufacturing a display panel using the same
A photo-alignment composition includes a compound comprising a repeat unit represented by Chemical Formula 1 and a solvent. The photo-alignment composition is coated on a first substrate and a second substrate facing the first substrate, thus forming alignment layers. A liquid crystal layer is formed between the first substrate and the second substrate. The photo-alignment composition includes a compound structure having a high decomposition rate and a functional group capable of a hydrogen bond, which is weaker than a covalent bond. Thus, a hardness of the alignment layer may be improved at a room temperature, and a hydrogen bonding functional group of the photo-alignment composition may be decomposed at a high temperature thus photo-aligning the alignment layer. Therefore, an afterimage of a screen may decrease, and a hardness of the alignment layer may increase.
US09745511B2 Phosphors
The present invention relates to europium-doped phosphors, to a process for the preparation thereof, and to the use of these compounds as conversion phosphors. The present invention furthermore relates to light-emitting devices which comprise the phosphor according to the invention.
US09745510B2 Fluoride fluorescent material and method for producing the same
A method for producing a fluoride fluorescent material includes: subjecting a mixture that contains a fluoride compound in a liquid medium to a pressurization treatment and a heating treatment, the fluoride compound having a chemical composition represented by the following formula: A2[M1−aMn4+aF6]. A is at least one cation selected from the group consisting of K+, Li+, Na+, Rb+, Cs+and NH4+, M is at least one element selected from the group consisting of Group 4 elements and Group 14 elements, and a is a number that satisfies 0
US09745503B2 Treatment fluids containing a boron trifluoride complex and methods for use thereof
Treatment fluids for use in subterranean formations, particularly sandstone and other siliceous formations, may contain a source of fluoride ions to aid in mineral dissolution. In some cases, it may be desirable to generate the fluoride ions from a fluoride ion precursor, particularly a hydrofluoric acid precursor, such as a boron trifluoride complex. Methods described herein can comprise providing a treatment fluid that comprises an aqueous base fluid, a boron trifluoride complex, and a chelating agent composition, and introducing the treatment fluid into a subterranean formation.
US09745501B1 Additive composition suitable for viscosity reduction of oil-based drilling fluid, oil-based drilling fluid and use thereof
The present invention relates to the well drilling field in petroleum industry, in particular to an additive composition suitable for viscosity reduction of oil-based drilling fluids, an oil-based drilling fluid and use thereof. The double-block copolymer mainly consists of a block A and a block B, wherein, the block A is composed of structural units represented by formula (1), the block B is composed of structural units represented by formula (2), and the number-average molecular weight of the block A is 1,500-10,000. The double-block copolymer provided in the present invention can be used as a viscosity reducer in oil-based drilling fluids, especially can be used as a viscosity reducer in high-density clay-free oil-based drilling fluids, and can greatly decrease the apparent viscosity and plastic viscosity of oil-based drilling fluids in high-temperature and high-pressure reservoir while maintaining appropriate shearing force, so as to increase the drilling rate and reduce drilling difficulties.
US09745500B2 Method for producing drilling fluid from biomass-derived oils
Disclosed is a method for producing a drilling fluid, comprising: a) preparing mixed fatty acids from a biomass-derived oil, b) subjecting the mixed fatty acids of step a) to an estolide reaction with a light acid to give an estolide, and c) esterifying the estolide of step b) with an alcohol to obtain the drilling fluid.
US09745499B2 Hexagonal boron nitride nanosheet/ceramic nanocomposite powder and producing method of the same, and hexagonal boron nitride nanosheet/ceramic nanocomposite materials and producing method of the same
The present disclosure relates to hexagonal boron nitride nanosheet/ceramic nanocomposite powder including surface-modified hexagonal boron nitride nanosheets which serve as a reinforcing agent for the matrix ceramic, and a method for producing the same, and a hexagonal boron nitride nanosheet/ceramic nanocomposite material including the hexagonal boron nitride nanosheet/ceramic nanocomposite powder and a method for producing the same.
US09745497B2 Composition comprising HFC and HFO
The present invention provides a composition comprising a mixture of HFC and HFO and having improved lubrication performance. Specifically, the present invention provides a composition comprising HFC and HFO, wherein the composition comprises 1) at least one of HFC-134a and HFC-134 as the HFC, 2) at least one of HFO-1234yf and HFO-1234ze as the HFO, and 3) at least one member selected from the group consisting of HCFC-1122, HCFC-124, CFC-1113, and 3,3,3-trifluoropropyne as a third component.
US09745496B2 Producing heating using working fluids comprising Z-1,1,1,4,4,4-hexafluoro-2-butene
Disclosed herein is a method for producing heating in a high temperature heat pump comprising condensing a vapor working fluid comprising Z-1,1,1,4,4,4-hexafluoro-2-butene, in a condenser, thereby producing a liquid working fluid. Also disclosed herein is a method of raising the maximum feasible condenser operating temperature in a high temperature heat pump apparatus comprising charging the high temperature heat pump with a working fluid comprising Z-1,1,1,4,4,4-hexafluoro-2-butene. Also disclosed herein is a composition comprising: (a) Z-1,1,1,4,4,4-hexafluoro-2-butene; (b) 2-chloropropane; and (c) at least one lubricant suitable for use at a temperature of at least about 150° C.; is wherein the 2-chloropropane is present in an amount effective to form an azeotrope or azeotrope-like combination with the Z-1,1,1,4,4,4-hexafluoro-2-butene. Also disclosed herein is a high temperature heat pump apparatus containing a working fluid comprising Z-1,1,1,4,4,4-hexafluoro-2-butene.
US09745489B2 Binders and materials made therewith
A curable aqueous composition is disclosed comprising a carbohydrate, a crosslinking agent, and an amine base, wherein the curable aqueous composition has a pH adjusted by the amine base. Further disclosed is a method of forming a curable aqueous solution.
US09745485B2 Water-based ink for ink-jet recording, ink cartridge, and ink-jet recording method
A water-based ink for ink-jet recording includes: a pigment; water; a nonionic surfactant having an ethylene oxide chain; an anionic surfactant having an ethylene oxide chain; and a penetrant having an ethylene oxide chain, wherein the nonionic surfactant, the anionic surfactant, and the penetrant satisfy the following conditions (I) to (III). −1≦X−Y≦1  condition (I): −1≦Y−Z≦1  condition (II): −1≦Z−X≦1  condition (III): X: an average value of the number of ethylene oxide groups in the ethylene oxide chain of the nonionic surfactant Y: an average value of the number of ethylene oxide groups in the ethylene oxide chain of the anionic surfactant Z: an average value of the number of ethylene oxide groups in the ethylene oxide chain of the penetrant.
US09745484B2 White ink composition for ink-based digital printing
A white ink composition for ink-based digital printing includes a white pigment. The white pigment is titanium dioxide. A method for ink-based digital printing includes applying dampening fluid to an imaging member to form a dampening fluid layer, patterning the dampening fluid layer using a laser imaging system, applying a white ink composition to the imaging member surface having the patterned dampening fluid disposed thereon to form an ink image, partially curing the ink image, and transferring the partially cured ink image to a printable substrate.
US09745481B2 High performance composite dielectric ink for ultracapacitors
The present invention is a dielectric ink and means for printing using said ink. Approximately 10-20% of the ink is a custom organic vehicle made of a polar solvent and a binder. Approximately 30-70% of the ink is a dielectric powder having an average particle diameter of approximately 10-750 nm. Approximately 5-15% of the ink is a dielectric constant glass. Approximately 10-35% of the ink is an additional amount of solvent. The ink is deposited on a printing substrate to form at least one printed product, which is then dried and cured to remove the solvent and binder, respectively. The printed product then undergoes sintering in an inert gas atmosphere.
US09745478B2 Pigmented paint formulation with a phosphorus acid functionalized latex binder and an associative thickener
The present invention relates to a composition comprising an aqueous dispersion of an associative thickener having a hydrophobic portion with a calculated log P in the range of from 2.7 to 5.0; and composite particles comprising phosphorus acid functionalized polymer particles adsorbed to the surfaces of TiO2 particles; wherein the phosphorus acid functionalized polymer particles have a core-shell morphology wherein the core protuberates from the shell. The composition of the present invention provides formulators with flexibility in their use of low and mid shear rate thickeners to balance paint performance properties.
US09745475B2 Use of a polymeric emulsion for the surface treatment of particles of mineral matter
The present invention relates to the use of a new polymeric aqueous emulsion for surface treating particles of mineral matter.
US09745470B2 Film-forming composition
A film-forming composition that contains a tricarbonyl-benzene hyperbranched-polymer cross-linker and a triazine-containing hyperbranch, as shown for example in the formula, can form a thin film that excels in terms of hardness and heat tolerance and exhibits a reduced decrease in index of refraction despite the addition of the cross-linker.
US09745468B2 Polyurethane resin composition for support pad and polyurethane support pad using the same
The present invention relates to a polyurethane resin composition for a support pad including a polyurethane resin, a DMF solvent, an anionic surfactant, and polyethylene glycol (PEG), and a polyurethane support pad including the polyurethane resin composition for a support pad. According to the present invention, long and large pores may be uniformly formed therein, and thus a support pad having an excellent compression rate and compression recovery rate may be provided.
US09745462B2 Polyethylene materials
Certain embodiments described herein are directed to polymer compositions including a base material, a secondary material and an antioxidant. The composition also includes crystalline regions and amorphous regions with the crystalline regions comprising at least 62% by volume of the composition. In some embodiments, the base material is an ultra high molecular weight polyethylene material and the secondary material is a polyethylene material that is different than the base material.
US09745460B2 Silicone acrylamide copolymer
The present invention relates to a silicone acrylamide copolymer of high acrylamide monomer content which has transparency and low modulus, employing the following configuration. The copolymer is suitably used for various kinds of medical devices, particularly ophthalmic lenses such as a contact lens, an intraocular lens, an artificial cornea, and is especially suitable for a contact lens. A copolymer comprising (A) a multi-functional (meth)acrylamide monomer having at least one siloxane bond and at least two (meth)acrylamide groups within a molecule and (B) a mono-functional linear silicone (meth)acrylamide monomer.
US09745458B2 Composite support material for three-dimensional printing
The present disclosure provides composite support material and associated methods used in the fabrication of three-dimensional objects. In one example, a composite support material for three-dimensional printing can include a soluble filament core that is soluble in a solvent and is encapsulated with an insoluble shell that is insoluble in the solvent. The composite support material is stable in air and, when printed, is dissolvable in the solvent.
US09745457B2 Aromatic vinyl copolymer and thermoplastic resin composition including the same
An aromatic vinyl copolymer is a polymer of a reaction mixture including: an aromatic vinyl compound; a vinyl cyanide compound; a first silicone compound having a weight average molecular weight of about 150 g/mol to less than about 6,000 g/mol and including at least two unsaturated reactive groups; and a second silicone compound having a weight average molecular weight of about 6,000 g/mol to about 100,000 g/mol and including at least two unsaturated reactive groups. A thermoplastic resin composition including the aromatic vinyl copolymer can exhibit excellent matting properties, impact resistance, and balance therebetween.
US09745455B2 Biaxially oriented matte polypropylene film
A multi-layer biaxially oriented polypropylene (BOPP) film with a novel formulation which exhibits matte appearance is disclosed. This improved formulation comprises a blend of high density polyethylene (HDPE), medium density polyethylene (MDPE), low density polyethylene (LDPE) or linear low density polyethylene (LLDPE) with polypropylene (PP) used in the core layer to achieve a matte appearance low gloss PP-based film that still exhibits typical properties of BOPP films with significantly lower haze than conventional matte films. The multi-layer BOPP film has additional layers such as a second polyolefin resin-containing layer, a metal layer, or combinations thereof.
US09745454B2 Tire
Tire having improved wet grip performance and improved resistance to breaking or chipping along with good fuel economy. The tire includes a tire component (preferably, a tire tread) formed of a vulcanized rubber composition. The vulcanized rubber composition is obtained by vulcanizing a specific unvulcanized rubber composition. The unvulcanized rubber composition comprises (a) a rubber component composed of natural rubber, polybutadiene rubber, and two different types of styrene-butadiene rubber, (b) a filler that includes silica, and (c) a silane coupling agent that incorporates a —C(═O)—S— moiety.
US09745451B2 Swellable compositions, articles formed therefrom, and methods of manufacture thereof
A swellable composition comprises: a matrix material; and a condensed expandable graphite material disposed in the matrix material. A seal arrangement comprises: a swellable member and a sealing member disposed on a surface of the swellable member; wherein the swellable member comprises a condensed expandable graphite material. The condensed expandable graphite material in the swellable composition and the swellable member has a bulk density of about 1 to about 8 g/cm3 and comprises expandable graphite.
US09745438B2 Method and system for manufacture and use of macroporous beads in a multiplex assay
Macroporous beads and a method of manufacturing and using such macroporous beads. wherein the beads are distinguishable for use in a multiplex assay. Preferably, the beads are distinguishable by two or more unique fluorochromes, and at least some of the beads are magnetically responsive. In a preferred form, some of the macroporous beads have interior pores with a different moiety from the exterior surface, allowing beads with different attached functional groups.
US09745435B2 Composition and method for making a cavitated bio-based film
Composition and method for making a multi-layer bio-based film having one or more cavitated layers. In one aspect, the multilayer flexible film has polylactic acid, an inorganic filler, and a cavitation stabilizer making up at least one film layer. In one aspect, the barrier web has a cavitated bio-based film layer. In another aspect, the print web has a cavitated bio-based film layer.
US09745434B2 Elastomeric body with elastic fire retardant coating
An elastomeric body suitable for anti-vibration and suspension is disclosed. The elastic body includes at least one layer of an elastic and flexible fire retardant coating covering at least a portion of the body. The at least one layer of fire retardant coating is non-halogenated and includes a fire retardant substance and an elastic binder material. The fire retardant substance includes expandable graphite. The at least one layer of coating has an elasticity greater than 20%.
US09745431B2 BOPP film having low shrinkage
The present invention relates to a new biaxially oriented polypropylene (BOPP) film, a process for the preparation of such film as well as the use of a polypropylene for the preparation of such film and an article comprising such film.
US09745430B2 Elastic monofilm and method of making a disposable hygiene article
The invention relates to an elastic monofilm having a film thickness between 20 μm and 100 μm, comprising an asymmetric styrene-diene triblock copolymer at a content between 35 wt % and 90 wt % as a first polymer substance A and comprising a second polymer substance B. According to the invention, polystyrene is provided at a content between 8 wt % and 40 wt % as the second polymer substance B.
US09745427B2 Composition and method of making shape memory polymer for biomedical applications
Shape memory polymers (SMP) based on poly vinyl alcohol (PVA) in the presence of 2-carboxyethyl acrylate oligomers (CEA), multi-wall carbon nanotubes (MWCNTs) and cross linked by ionizing radiation were investigated. Chemical crosslinking by glutaraldehyde for PVA in the presence of CEA and MWCNTs was also studied. Radiation cross linked SMP exhibits good temperature responsive shape memory behavior as demonstrated by thermal properties of radiation investigated by dynamic mechanical analysis. Transition temperature at Tan δ of radiation cross linked SMP decreased significantly by 6 and 13° C. due to addition of MWCNTs. The developed SMP exhibited promising shape memory behavior of radiation cross linked SMP for biomedical applications between temperatures range of Tan δ. Results on the gel fraction revealed significant reduction in swelling and increase in gelation due to chemical cross linking with glutaraldehyde. The radiation cross linked SMP reached 100% gelation at an irradiation dose of 50 kGy.
US09745425B2 Cycloaliphatic polyphosphite
A polymeric polyphosphite and copolymeric polyphosphite is described which contains a cycloaliphatic moiety, preferably cyclohexane dimethanol, in the polyphosphite backbone chain. Incorporation of the polymeric polyphosphite into synthetic polymers reduces the yellowness index of any polymer into which the polymeric polyphosphite additive has been added, as well as increased hydrolytic stability as well as increased resistance to migration in food packaging.
US09745424B2 Insoluble and branched polyphosphonates and methods related thereto
Insoluble polyphosphonates produced via a transesterification process, methods for preparing such insoluble polyphosphonates and polymer compositions and articles of manufacture including such insoluble polyphosphonates are described herein.
US09745420B2 Polymers containing substituted oligo-triarylamine units and electroluminescence devices containing such polymers
The present invention relates to polymers containing oligo-triarylamine repetition units that are substituted in the ortho position, a method for the production thereof, and use thereof in electronic devices, particularly in organic electroluminescence devices, known as OLEDs (OLED=organic light emitting diodes). The present invention further relates to organic electroluminescence devices containing these polymers.
US09745419B2 Aqueous polyglycidol synthesis with ultra-low branching
Disclosed herein are glycidol-based polymers, nanoparticles, and methods related thereto useful for a variety of applications, including, but not limited to, drug delivery. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US09745418B2 Copolycarbonate and composition comprising the same
The present invention relates to copolycarbonates and a composition comprising the same. The copolycarbonate according to the present invention has a structure in which specific siloxane compounds are introduced in the main chain of polycarbonate and thus exhibits the effects of improving impact strength at room temperature, impact strength at low-temperature and melt index.
US09745415B2 Sulfonated co-polyesters and method for manufacturing
A method of forming a polymer includes polymerizing a first pre-polymer, produced by the reaction of a dicarboxylic acid, or ester thereof with a first alkylene diol; with a second pre-polymer produced by the reaction of an aromatic sulfonate or a salt thereof, or ester thereof, with a second alkylene diol; to form a metal sulfonate co-polymer; reacting the metal sulfonate co-polymer with a fast crystallizing polyester block having a degree of polymerization of at least about 20 to provide an amorphous sulfonated co-polyester; and crystallizing the amorphous sulfonated co-polyester to form a crystallized sulfonated co-polyester.
US09745411B2 Resin composition, resin sheet, cured resin sheet, resin sheet structure, cured resin sheet structure, method for producing cured resin sheet structure, semiconductor device, and LED device
A resin composition including an epoxy resin monomer, a novolac resin including a compound having a structural unit represented by Formula (I), and a filler; in which the filler has at least 4 peaks in a particle size distribution measured by laser diffractometry, in which four of the peaks are present respectively in ranges of not less than 0.01 μm and less than 1 μm, not less than 1 μm and less than 10 μm, from 10 μm to 50 μm, and from 20 μm to 100 μm, and in which a peak present in a range of from 10 μm to 50 μm includes an aluminum oxide particle, and a peak present in a range of from 20 μm to 100 μm includes a boron nitride particle. In Formula (I) each of R1, R2 and R3 independently represents a hydrogen atom, an alkyl group, or the like. m represents 0 to 2, and n represents 1 to 7.
US09745410B2 Aromatic aldehyde, and epoxy resin curing agent and epoxy resin composition comprising the aromatic aldehyde
There are provided a novel aromatic aldehyde compound capable of providing an epoxy resin coating film and an epoxy resin cured material satisfying all of the excellent surface property (smoothness, gloss), drying property, water resistance, transparency and adhesion, and an epoxy resin curing agent and an epoxy resin composition containing the aromatic aldehyde compound. The aromatic aldehyde has a branched alkyl group having 10 to 14 carbon atoms.
US09745406B2 Curable composition
Provided is a curable composition which realizes compatibility between curability and toughness, shows rapid curability and excellent storage stability, and does not require any tin catalyst. The curable composition comprises: (A) a vinyl-based resin obtained by causing a compound (I) represented by the following general formula (1) and a compound (II) represented by the following general formula (2) to react with each other; (B) a urethane-based resin obtained by causing a hydroxyl group-containing organic polymer, a polyisocyanate compound, a compound (III) represented by the following general formula (3), and an amine compound to react with one another; and (C) a curing catalyst.
US09745405B2 Polymer, polymer modified titanium dioxide pigment, and method of forming a pigmented paint formulation
A new polymer that is capable of forming a composite with titanium dioxide particles and latex particles when admixed therewith is provided. The new polymer includes a water soluble polymer backbone, a first functional group attached to the polymer backbone and having an affinity for latex, and a second functional group attached to the polymer backbone and capable of forming a bond with titanium dioxide. A polymer modified titanium dioxide pigment and a method of forming a pigmented paint formulation are also provided.
US09745404B2 Resin molded article for automobile interior material
Provided is a resin molded article for an automobile interior material, the resin molded article achieving both resin strength permitting formation of a thin film, and crease resistance. This molded article is to be used in an automobile interior material, the resin molded article being obtained by slush-molding a powdered thermoplastic urethane urea resin composition (P) that satisfies (1)-(5) below, said resin composition (P) containing an additive and a thermoplastic urethane urea resin (U) obtained by reacting a high-molecular diol (a), a linear alkane diol (b), a monool (c), a diamine (d), and an organic diisocyanate (e): (1) (a) contains a specific polyester diol; (2) the weight of (b) is within a specific range relative to the total weight of (a)-(e); (3) the tensile strength of a film comprising (P) is 8.0 MPa or higher; (4) the storage modulus of (P) at 130° C. is 0.1-5.0 MPa; (5) the ratio of the storage modulus of (P) at 50° C. to the storage modulus at 23° C. by a specific measurement method is 50% or higher.
US09745403B2 Polymer raw material and polymer material
To provide a polymer material having properties that allow the polymer material to replace a polyimide and a polyamide synthesized from a petroleum raw material, said polymer material being synthesized from a raw material derived from natural molecules. [Solution] This polymer material is obtained by polymerizing a polymer raw material comprising a dimer of 4-amino cinnamic acid or a dimer of a 4-amino cinnamic acid derivative, which are natural molecules, wherein the carboxyl group is protected by an alkyl chain. The TGA curve of a polyamide acid (PAA-1) and a polyimide (PI-1) according to the present invention is shown in FIG. 5.
US09745400B2 Method for producing polyacetal copolymer
A high-quality polyacetal produced by a process including supplying a raw material comprising trioxane, a comonomer capable of copolymerizing with trioxane and a non-volatile protonic acid to a reactor of a continuous stirring/mixing machine type; carrying out a polymerization reaction of the raw material to produce a reaction mixture; vaporizing an unreacted monomer to separate the unreacted monomer from the reaction mixture and supplying the unreacted monomer to the raw material supplying; collecting a polyacetal copolymer from the reaction mixture into a collection unit which is arranged downstream from a discharge port and is adjusted to have a gauge pressure of 0.2 kPa or more; and adding a basic compound to the collected polyacetal and then subjecting the resultant mixture to a melt-kneading treatment to deactivate the non-volatile protonic acid.
US09745397B2 Multistage process for producing low-temperature resistant polypropylene compositions
A process for polymerizing propylene in the presence of a polymerization catalyst by copolymerizing propylene with a comonomer selected from the group of ethylene and C4-C10 alpha-olefins in three polymerization stages. The polymer produced in the first polymerization stage has the highest melt flow rate and the lowest content of comonomer. The polymer produced in the last polymerization stage has the lowest melt flow rate and the highest content of comonomer. The polymer composition produced by the process has good mechanical properties and can be used for making pipes. The process has a good productivity.
US09745395B2 Propylene-based impact copolymers
A propylene-based impact copolymer (ICP) and composition including the ICP, the ICP comprising a polypropylene homopolymer and within the range of from 10 wt % to 45 wt % of propylene copolymer based on the weight of the ICP, wherein the copolymer comprises from 20 wt % to 44 wt % ethylene, 1-butene, 1-hexene and/or 1-octene derived units and from 80 to 60 wt % propylene-derived units based on the weight of the propylene copolymer, the propylene-based impact copolymer having a Melt Flow Rate (230° C./2.16 kg) within the range of from 10 g/10 mm to 50 g/10 mm and an Elongation at Break of greater than 70%.
US09745393B2 Method for preparing novel anionic polymerization initiator and conjugate diene system copolymer using same
Disclosed are an anionic polymerization initiator, which is a reaction product of an organometallic compound and a compound including an etheric oxygen atom-containing alkyl group represented by specific Chemical Formula, and a method of preparing a conjugated diene-based copolymer using the same.
US09745391B2 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates therefrom and use of the polymers and condensates
A compound has at least three functionalities, including a first functionality (a) that is a sulfonate group or a sulfate group of the formula —(O)d—SO3M with d=0 or 1 and with M=hydrogen or a monovalent metal cation or a corresponding portion of a multivalent metal cation; a second functionality (b) that is a (meth)acryl residue; and a third functionality (c) that is a carboxylic acid function and/or a thioether group. When the compound is free of silicon, the sulfonate or sulfate group and the (meth)acryl residue are separated from each other by a hydrocarbon-containing residue having a carbon chain. The carbon chain is interrupted by S or NH, or the carbon chain contains a linking group, selected from C(O)NH, NHC(O), NR8C(O), NHC(O)O, NR8C(O)O, NHC(O)NH, C(O)NHC(O) and —C(O)S—, wherein R8 is alkyl or alkenyl or a (meth)acryl group.
US09745388B2 Butyl rubber with increased impermeability
Surface modification methods based on a combination of plasma and chemical treatments render an unfilled butyl rubber surface highly reactive toward organosilanes, allowing formation of an organosilane self-assembled monolayer (SAM). Plasma oxidation of the butyl rubber surface followed by vapor deposition of SiCl4 produces a hydrophilic surface suitable for anchoring organosilanes. Fabrication of SAMs on this hydrophilic butyl rubber surface with n-octadecyltrichlorosilane (OTS) and trichloro(1H,1H,2H,2H-perfluorooctyl)silane (FOTS) via vapor deposition resulted in a 15% and 25% decrease in gas permeability, respectively, with no change in optical transparency of the butyl rubber.
US09745384B2 Peptides useful for modulating histone demethylase function
We described peptides and peptide fragments that can be used to inhibit cyclin D1 and cyclin E1, function of both of which is involved in malignant growth. Methods of treatment of cancer by inhibiting interaction between NPAC and LSD2 are also provided.
US09745382B1 Bispecific anti-HER2 antibody
The present invention relates to humanized bispecific anti-HER2 antibodies that comprise one antigen binding site containing variable regions of heavy and light chain of trastuzumab, and another antigen binding site containing variable regions of heavy and light chain of pertuzumab. The bispecific anti-HER2 antibodies is effective for treating cancer, such as breast cancer, gastric cancer, or ovarian cancer. Preferred bispecific anti-HER antibodies of the present invention are afucosylated antibodies.
US09745381B2 Bispecific scFv immunofusion (BIf)
Certain embodiments are directed to a bispecific immunoglobulin that is capable of binding cell surface molecules on a target cell, such as cancer cells, and cell surface molecules on immune effector cell, such as cytotoxic T lymphocytes, resulting in the targeted killing of target cells. In certain aspects a Bif is a polypeptide comprising a first target binding domain that specifically binds a cancer cell, a second effector binding domain that specifically binds an immunologic effector, and an immunoglobulin constant region linker operatively coupling the first and second binding domain.
US09745372B2 TNF binders
The present invention relates to amino acid sequences, compounds and polypeptides binding to tumor necrosis factor alpha (“TNF” or “TNF-alpha”). In particular, the present invention relates to improved heavy-chain immunoglobulin single variable domains (also referred to herein as “ISV's” or “ISVDs”) binding to tumor necrosis factor alpha, as well as to proteins, polypeptides and other constructs, compounds, molecules or chemical entities that comprise such ISVDs, collectively TNF binders. Other aspects, embodiments, features, uses and advantages of the invention will be clear to the skilled person based on the disclosure herein.
US09745370B2 Antibodies to sericin and methods and kits using same
The present invention relates to antibodies that bind to a polypeptide at an epitope in the amino acid sequence of SEQ ID NO: 1 (e.g., a sericin polypeptide). The invention also provides methods and kits using the antibodies of the invention. In some embodiments, the antibody binds to a polypeptide at an epitope in the amino add sequence of SEQ ID NO: 2. In some embodiments, the antibody binds to a polypeptide at an epitope in the amino add sequence of SEQ ID NO: 3. In some embodiments, the polypeptide is a sericin polypeptide (e.g., a sericin isoform 1B polypeptide). In a related aspect, the invention features a method for selectively detecting sericin in a sample.
US09745365B2 Anti-influenza B virus hemagglutinin antibodies and methods of use
The present invention provides anti-influenza B virus hemagglutinin antibodies, compositions comprising anti-influenza B virus hemagglutinin antibodies, and methods of using the same.
US09745363B2 Compositions and methods for inhibiting thrombogenesis
The invention is directed to a composition comprising an (one or more) isolated peptide comprising a BF01 peptide, variants of a BF01 peptide and/or mutants of a BF01 peptide. In particular aspects, the composition is a pharmaceutical composition. The composition(s) can be used to inhibit thrombogenesis, selectively inhibit the intrinsic pathway of blood coagulation and selectively inhibit FX1 in an individual in need thereof comprising administering an effective amount of all or a biologically active portion of a BF01 peptide, one or more variants thereof and/or one or more mutants thereof.
US09745361B2 Cytokine-based fusion proteins for treatment of immune disorders
The present invention provides fusion proteins including an autoimmune antigen, an allergen antigen or an alloantigen, and an anti-inflammatory cytokine. Compositions and methods including the fusion proteins are also provided.
US09745360B2 Dual GLP1/GIP or trigonal GLP1/GIP/glucagon agonists
The present invention relates to exendin-4 derivatives and their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as reduction of excess food intake.
US09745358B2 Peptides and compositions for treatment of joint damage
The present invention provides new protease resistant polypeptides, as well as compositions and methods for treating, ameliorating or preventing conditions related to joint damage, including acute joint injury and arthritis.
US09745354B2 Compositions relating to a mutant Clostridium difficile toxin and methods thereof
In one aspect, the invention relates to an immunogenic composition that includes a mutant Clostridium difficile toxin A and/or a mutant Clostridium difficile toxin B. Each mutant toxin includes a glucosyltransferase domain having at least one mutation and a cysteine protease domain having at least one mutation, relative to the corresponding wild-type C. difficile toxin. The mutant toxins may further include at least one amino acid that is chemically crosslinked. In another aspect, the invention relates to antibodies or binding fragments thereof that binds to said immunogenic compositions. In further aspects, the invention relates to isolated nucleotide sequences that encode any of the foregoing, and methods of use of any of the foregoing compositions.
US09745353B2 Production of anti-peptide antibodies
Anti-peptide antibodies (APAs) are extremely important tools for biomedical research. Many important techniques, such as immunoblots, ELISA immunoassays, immunocytochemistry, and protein microarrays are intrinsically linked to APA function and completely dependent on APA quality. Unfortunately, not all commercially-available APAs have good antigen binding characteristics; as a result, researchers are often unable to perform high quality protein analysis experiments. This disclosure describes a new method for the scalable production of polyclonal APAs using recombinant antigens. These recombinant peptide antigens have several advantages over traditional peptide antigens which improve the ease and speed of antibody production. The recombinant antigens can be scalably produced and purified much faster than traditional synthetic peptide-conjugates. These recombinant antigen-carriers are designed to specifically aggregate in vivo after administration into the host; this aggregation greatly enhances immunogenicity and may eliminate the need for the use of chemical adjuvants which cause physical irritation and discomfort to the host.
US09745352B2 Influenza treatment and/or characterization, human-adapted HA polypeptides; vaccines
The present invention provides, among other things, methods, reagents, and systems for the treatment, detection, analysis, and/or characterization of influenza infections.
US09745350B2 HER3 binding polypeptides
The present disclosure relates to polypeptides which bind to human epidermal growth factor receptor 3 (HER3) and to use of such polypeptides in imaging and therapy. The disclosure provides an HER3 binding polypeptide comprising a HER3 binding motif, which motif consists of the amino acid sequence EKYX4AYX7EIW X11LPNLTX17X18QX20 AAFIGX26 LX28D (SEQ ID NO:110).
US09745341B2 Tubulysins and processes for preparing
Processes are described for the preparation of tubulysins. The processes are useful for preparing predetermined mixtures of tubulysins, preparing single tubulysins from mixtures of tubulysins, and for converting one tubulysin into a different tubulysin. The tubulysins described herein are useful in treating diseases and disease states that include pathogenic cell populations.
US09745340B2 Method for the separation of proteins containing an albumin-binding
The disclosure provides a method of separation of at least one ABD-containing molecule present in a liquid from other constituents in the liquid, comprising a step of affinity separation, in which step is used, as affinity ligand, an ABD binding polypeptide comprising an ABD binding motif BM, which motif consists of an amino acid sequence selected from (SEQ ID NO: 166) EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D and amino acid sequences with at least 89% identity thereto.
US09745334B2 Cytotoxic-drug delivering molecules targeting HIV (CDM-Hs), cytotoxic activity against the human immunodeficiency virus and methods of use
The present invention is directed to new bifunctional compounds and methods for treating HIV infections. The bifunctional small molecules, generally referred to as CDM-Hs, function through orthogonal pathways, by inhibiting the gp120-CD4 interaction, and by introducing cytotoxic moieties to gp120-expressing cells, thereby causing cell death and preventing cell infection and spread of HIV. It is shown that CDM-Hs bind to gp120 and gp-120 expressing cells competitively with CD4, and these compounds cause cell death of HIV-infected cells, thereby decreasing viral infectivity. Compounds and methods are described herein.
US09745331B2 Therapeutic bisphosphonates
The invention provides novel pyrophosphate synthase inhibitors of formula I and formula II as well salts thereof; the invention also provides compositions comprising such inhibitors and methods for their use.
US09745329B1 Method of preparing silylative-reduced N-heterocyclic compound using organoboron catalyst
Provided is a method of preparing a silylative-reduced N-heterocyclic compound by reducing an N-heteraromatic compound including a sp2 hybridized nitrogen atom while simultaneously introducing a silyl group into a beta-position with respect to a nitrogen atom of the N-heteroaromatic compound, using a silane compound, in the presence of an organoboron catalyst.
US09745327B2 Bisphenolate transition metal complexes, production and use thereof
Bis phenolate transition metal complexes are disclosed for use in alkene polymerization, with optional chain transfer agent, to produce polyolefins.
US09745325B2 Fused heterocyclic compound
The present invention provides a fused heterocyclic compound that has CDK 8 and/or CDK 19 inhibitory activity. The present invention provides a compound represented by formula (I) (wherein the symbols are as defined in the description) or a salt thereof.
US09745320B2 Five-and-six-membered heterocyclic compound, and preparation method, pharmaceutical composition and use thereof
A five-and-six-membered heterocyclic compound as represented by general formula I, pharmaceutically acceptable salt, metabolite, metabolic precursors or drug precursors thereof, preparation method, pharmaceutical composition, and use thereof; the five-and-six-membered heterocyclic compound has activity as a Janus kinase (JAK) inhibitor, and can be used to prepare drugs for treating diseases caused by the abnormal activity of kinase, such as cell proliferation diseases like cancer.
US09745311B2 Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
The present invention relates to pyrazine derivatives of Formula I, and pharmaceutical compositions including the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer.
US09745298B2 Synthesis of a compound that modulates kinases
The present disclosure provides processes for the preparation of a compound of formula I: or a salt thereof, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
US09745297B2 Compounds as modulators of RORC
The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
US09745296B2 Salts, co-crystals, and polymorphs of an anxiolytic compound
The present invention provides amorphous arid crystalline forms of 1-ethyl-6-(indan-2-ylamino)-3-(morpholine-4-carbonyl)-1,8-naphthyridin-4-one (compound 1), and salts, co-crystals, and pharmaceutical compositions thereof. The invention also provides methods of treating and/or preventing a disease, such as a central nervous system disease (e.g., an anxiety disorder), using the amorphous and crystalline forms, and salts, co-crystals, and pharmaceutical compositions thereof.
US09745294B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors
A compound is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The subject has type 2 diabetes; renal hypertrophy or hyperplasia associated with diabetic nephropathy; Tay-Sachs; Gaucher's; or Fabry's disease. Methods of decreasing plasma TNF-α, lowering blood glucose levels, decreasing glycated hemoglobin levels, inhibiting glucosylceramide synthase, and lowering glycosphingolipid concentrations in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.
US09745293B2 Sweet flavor modifier
The present invention includes compounds having structural formula (Ia): or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.
US09745292B2 Compounds, compositions, and methods for increasing CFTR activity
The disclosure encompasses compounds having e.g., Formula (Ia) or (Ib), compositions thereof, and methods of modulating CFTR activity. The disclosure also encompasses methods of treating a condition associated with CFTR activity or condition associated with a dysfunction of proteostasis comprising administering to a subject an effective amount of a compound of Formula (I) or (Ib).
US09745291B2 PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.
US09745289B2 Aldosterone synthase inhibitors
The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2 and R3, are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
US09745288B2 Compounds and methods for treating cancer by inhibiting the urokinase receptor
Compounds and methods for treating or preventing cancer associated with binding to the urokinase receptor are provided. Biological processes affected by the compounds include cell migration, cell growth, cell adhesion, angiogenesis, cancer cell invasion, apoptosis, tumor formation, tumor progression, metastasis, degradation of the extracellular matrix, pericellular proteolysis, activation of plasminogen, changes in the levels of an extracellular protease, and changes in the levels of a VEGF receptor.
US09745286B2 Triazole agonists of the APJ receptor
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
US09745285B2 Heteroaryl substituted pyrazoles
Compounds of formula (I), which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
US09745279B2 Sirtuin activator
The present invention provides a sirtuin activator with an active component composed of black ginger or a black ginger extract, which is easily obtainable, extremely safe, and eaten from old. The present invention further provides a sirtuin activator with an active component of polyalkoxyflavonoid compound represented by general formula (I) and having a sirtuin activation effect that is 10 folds that of resveratrol or higher: wherein, R1 to R7 are each independently a hydrogen atom, a hydroxyl group, or a C1 to C6 lower alkoxy group.
US09745278B2 Group of STAT3 pathway inhibitors and cancer stem cell pathway inhibitors
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such compounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof, and to the pharmaceutical composition of relevant compounds, and to the specific methods of administration of these compounds.
US09745277B2 Synthetic process for preparing 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate
Disclosed herein are processes for forming 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate:
US09745276B2 Crystal modifications of elobixibat
The present invention relates to crystal modifications of N-{(2R)-2-[({[3,3-dibutyl-7-(methyl-thio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-8-yl]oxy}acetyl)amino]-2-phenylethanolyl}glycine (elobixibat), more specifically crystal modifications I, IV, MeOH-1, EtOH-1, 1-PrOH-1 and 2-PrOH-1. The invention also relates to a process for the preparation of these crystal modifications and to a pharmaceutical composition comprising crystal modification IV.
US09745275B2 Pain-related compound and medical composition
Provided is a pain-related compound, a pain-related pharmaceutical composition, and use of the same. Provided in one or more embodiments is a compound represented by Formula (I), a prodrug of the same, or a pharmaceutically permissible salt of any of the same.
US09745273B2 Phenazine derivatives as anti-neoplastic agents and anti-infective agents
Novel phenazine derivatives, methods for their preparation and their medical use, in particular as anti-neoplastic agents and anti-infective agents, are provided. Novel methods for the preparation of iodinin and myxin are also provided.
US09745269B2 Supercritical fluid extraction of bis-benzyl isoquinolines
An improved process for obtaining at least one bis-benzyl isoquinoline alkaloid from botanical material involves contacting the botanical material with a supercritical fluid having as a major component one or more aliphatic hydrocarbon compounds, such as alkanes, alkenes, cyclic aliphatic hydrocarbons, or a combination of these compounds.
US09745267B2 Compounds as modulators of RORC
The present invention encompasses compounds of the formula (I): wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
US09745266B2 Indoline alkaloid compounds
The present invention relates to indoline alkaloid compounds. In particular, indoline alkaloid compounds of the invention have antibacterial activity and/or are capable of resensitizing the susceptibility of methicillin-resistant S. aureus to a β-lactam antibiotic. The present invention also relates to a method for producing and using the same.
US09745261B2 Inhibitors of the MITF molecular pathway
Provided herein are compounds of the formula (IV) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful as MITF inhibitors, MITF pathway inhibitors and for the treatment of cancer.
US09745259B2 Process for preparing alcohol ether sulfates
A process for preparing an alcohol ether sulfate is disclosed which comprises: (a) sulfating an alkoxylated alcohol; and (b) neutralizing the sulfated product of step (a) in the presence of a base and a co-solvent having a flash point of at least 60° C.
US09745258B1 Cyclic process for producing taurine
There is disclosed a process for producing taurine from ammonium isethionate by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. Alkali taurinate is reacted with ammonium isethionate to obtain taurine and to regenerate alkali isethionate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.
US09745254B2 Two-step and one-pot processes for preparation of aliphatic diisocyanates
The present invention relates to using a two-step (thermolysis) or one-pot process to prepare aliphatic diisocyanates from aliphatic diamines and diaryl carbonates. Polyisocyanates can also be prepared from polyamines and diaryl carbonates. The present synthetic processes do not apply phosgene or highly toxic reagents and chloro-solvents during the entire procedure.
US09745253B2 Alpha-cinnamide compounds and compositions as HDAC8 inhibitors
The present invention relates to inhibitors of histone deacetylases, in particular HDAC8, that are useful for the treatment of cancer and other diseases and disorders, as well as the synthesis and applications of said inhibitors.
US09745250B2 Process to crystallize chelating agents
The present invention relates to a process to crystallize a chelating agent containing a step of adding seeds to a saturated or supersaturated aqueous solution or dispersion of the chelating agent and a subsequent step of milling the dispersion, wherein the step of milling the dispersion is performed using equipment operating at at least 1,000 rpm, and to products obtainable by such process.
US09745240B2 Metal free process for allylic oxidation
The patent discloses a novel metal free process for the preparation of corresponding phenol and ketone via allylic oxidation of substituted cyclohexenes. Air is used as oxidant in the present process and can be used as such or optionally selected from pure oxygen or atmospheric oxygen. Moreover, the process of the present invention utilizes easily available starting materials and is a green eco-friendly, convenient and economical process with high yield of >60% and high selectivity.
US09745225B2 Dielectric composition and electronic component
A dielectric composition containing a complex oxide represented by the formula of xAO-yBO-zC2O5 as the main component, wherein A represents at least one element selected from the group including Ba, Ca and Sr, B represents Mg, and C represents at least one element selected from the group including Nb and Ta, and x, y and z meet the following conditions, x+y+z=1.000, 0.000
US09745222B2 Apparatus and methods for producing gypsum wallboard
An apparatus for production of a gypsum product is provided which comprises a conveyer comprising a conveyer belt and means for rotating the conveyer belt; means for forming a gypsum product; and at least one laser scanner positioned over the conveyer belt at the location where the scanner scans at least one edge of the gypsum product which is at least partially set; and the laser scanner is in communication with a processor. Methods for forming a gypsum product with the apparatus are provided as well.
US09745219B2 Apparatus for forming front glass for display of electronic device
A forming apparatus for cleanly forming front glass for a portable terminal includes an upper mold 10 including an upper mold body 12 of a specific thickness and a protruded portion 14 protruded from the bottom surface of the upper mold body and a lower mold 20 including a lower mold body 22 of a specific thickness and a concave portion 24 concavely formed in the top surface of the lower mold body in such a way as to correspond to the protruded portion. Curved surface forming portions 16 and 26 are formed in the edge portion of the protruded portion 14 of the upper mold and the edge portion of the concave portion of the lower mold. The curved surface forming portions 16 and 26 are formed into line contact portions 16a and 26a coming into line contact with the end portions of the top and bottom surfaces of the glass, respectively.
US09745218B2 Lithium silicate glass ceramic for fabrication of dental appliances
The present invention relates to a method of fabricating an improved lithium silicate glass ceramic and to that material for the manufacture of blocks for dental appliances using a CAD/CAM process and hot pressing system. The lithium silicate material has a chemical composition that is different from those reported in the prior art with 1 to 10% of germanium dioxide in final composition. The softening points are close to the crystallization final temperature of 800° C. indicating that the samples will support the temperature process without shape deformation.
US09745216B2 Hydrophobically modified polyamine scale inhibitors
Hydrophobically modified Si-containing polyamines are useful for treating scale in industrial process streams. Preferred hydrophobically modified Si-containing polyamines are particularly useful for treating aluminosilicate scale in difficult-to-treat industrial process streams, such as in the Bayer alumina process streams, nuclear waste streams and kraft paper mill effluent streams.
US09745213B2 Scale suppression apparatus, geothermal power generation system using the same, and scale suppression method
A scale suppression apparatus capable of suppressing in a low-priced manner the generation of silica-based scale and calcium-based scale in the influent water, a geothermal power generation system using the same, and a scale suppression method are provided. The apparatus includes a first addition unit configured to add liquid containing a chelating agent and an alkaline agent to influent water flowing through a pipe arrangement to make the influent water higher than pH 7, a second addition unit configured to add an acid substance to the influent water to make the influent water lower than pH 7, and a controller configured to alternatively switch between the operation of the first addition unit and the operation of the second addition unit. The controller controls the switching of the first addition unit and the second addition unit based on the signals output from a scale detection unit and a pH meter.
US09745206B2 Outlet for shower or faucet head
Removable and replaceable outlets for point-of-use showers or faucets, filter devices, and methods and systems including the outlets and/or filter devices, are disclosed.
US09745204B2 Method of producing barium titanate
A method of producing barium titanate that includes making a slurry by dispersing barium titanate powder in a solvent such as ethanol. Then, in a high-pressure vessel, substituting supercritical fluid including carbon dioxide gas, for example, for the solvent in the slurry. Then, separating the barium titanate powder from the supercritical fluid by gasifying the supercritical fluid. Then, performing a heat treatment on the separated barium titanate powders to produce the barium titanate.
US09745203B2 Non-caking salt composition, preparation process and use thereof
The present invention relates to a sodium chloride composition comprising an iron complex of tartaric acid wherein between 55 and 90% by weight of the tartaric acid is meso-tartaric acid. The present invention furthermore relates to a process to prepare such a sodium chloride composition and to the use of such a sodium chloride composition.
US09745196B2 Process for producing graphite film and graphite film produced thereby
In order to obtain a graphite film having an excellent thermal diffusivity, a high density, and excellent flatness without flaws, recesses and wrinkles on the surface, the process for producing a graphite film according to the present invention comprises the graphitization step for a raw material film made of a polymer film and/or a carbonized polymer film and/or the post-planar pressurization step for the film in this order to prepare a graphite film, wherein the graphitization step is a step of thermally treating two or more stacked raw material films at a highest temperature of 2,000° C. and includes a method of electrically heating the raw material films themselves and/or a method of thermally treating the films while applying pressure to the films planarly, and the post-planar pressurization step includes a method of planarly pressurizing the one raw material film or the multiple stacked raw material films after graphitization by single-plate press or vacuum press.
US09745192B2 Target holders, multiple incidence angle, and multizone heating for BNNT synthesis
In the synthesis of boron nitride nanotubes (BNNTs) via high temperature, high pressure methods, a boron feedstock may be elevated above its melting point in a nitrogen environment at an elevated pressure. Methods and apparatus for supporting the boron feedstock and subsequent boron melt are described that enhance BNNT synthesis. A target holder having a boron nitride interface layer thermally insulates the target holder from the boron melt. Using one or more lasers as a heat source, mirrors may be positioned to reflect and control the distribution of heat in the chamber. The flow of nitrogen gas in the chamber may be heated and controlled through heating elements and flow control baffles to enhance BNNT formation. Cooling systems and baffle elements may provide additional control of the BNNT production process.
US09745189B1 MEMS device with isolation sub-frame structure
An embodiment of a microelectromechanical systems (MEMS) device is provided, which includes a substrate; a proof mass positioned in space above a surface of the substrate, wherein the proof mass is configured to pivot on a rotational axis parallel to the substrate; an anchor structure that includes two or more separated anchors mounted to the surface of the substrate, wherein the anchor structure is aligned with the rotational axis; and an isolation sub-frame structure that surrounds the anchor structure and is flexibly connected to each of the two or more separated anchors of the anchor structure, where the proof mass is flexibly connected to the isolation sub-frame structure.
US09745188B1 Microelectromechanical device and method for forming a microelectromechanical device
A microelectromechanical device may include: a semiconductor carrier; a microelectromechanical element disposed in a position distant to the semiconductor carrier; wherein the microelectromechanical element is configured to generate or modify an electrical signal in response to a mechanical signal and/or is configured to generate or modify a mechanical signal in response to an electrical signal; at least one contact pad, which is electrically connected to the microelectromechanical element for transferring the electrical signal between the contact pad and the microelectromechanical element; and a connection structure which extends from the semiconductor carrier to the microelectromechanical element and mechanically couples the microelectromechanical element with the semiconductor carrier.
US09745187B2 Carbonated fluid dispenser with ultrasonic foaming mechanism
The embodiment relates to beverage dispensing, and more particularly to the dispensing of a beverage, from a beverage container into a vessel, providing a portion of the beverage as foam atop the dispensed beverage. To avoid the reduction of absorbed carbon dioxide in a carbonated beverage, increased atmospheric pressure is employed to move the beverage from the container through the apparatus and into the vessel. An oscillating means provides a sonic wave through a conduit and the liquid therein; the sonic wave initiates the reaction between the carbon dioxide and the ingredients in a carbonated beverage to cause the liquid to foam prior to dispensing into the vessel.
US09745176B2 Method for retrieving storage racks from a tank freezer using a retrieval crane, and related combinations
A method for retrieving storage racks in a tank freezer includes positioning a retrieval crane adjacent to the tank freezer such that a base of the retrieval crane is positionable underneath a bottom wall of a tank body. The retrieval crane includes a boom extending upwardly and laterally outwardly over the base so that a retention hook at a free end of a cable associated with the boom may be extended or retracted relative to the tank freezer. More specifically, the cable may be moved to extend the hook through the opening of the tank freezer into a storage space, and then retract the hook to lift and then hold a selected storage rack in a hoisted position. The method avoids the use of manual hoisting of storage racks, and the retrieval crane may be used with any of a plurality of similar tank freezers located in a larger facility.
US09745169B2 Safety system for an elevator, elevator system, and method for operating such a safety system
A safety system for an elevator that includes at least one control unit, which control unit is operable in at least two different operating modes. The safety system has at least one electronic lock connected with the control unit, and is connectable, or connected, with at least one electronic key. The control unit is programmed, or programmable, in such that, in the presence of a connection between the electronic key and the electronic lock, it is only operable in one operating mode of a first subset of the operating modes and, in the absence of a connection between the electronic key and the electronic lock, it is only operable in one operating mode of a second subset of the operating modes. A maintenance mode is only available in the second subset of the operating modes.
US09745160B2 Paper conveying apparatus, jam detection method, and computer program
Provided is a paper transporting device and the like capable of suppressing errors in determining jam occurrences. A paper transporting device has: a transport mechanism; an audio signal output unit that outputs an audio signal according to the sound generated during paper transport; an audio jam determination unit that determines, on the basis of the audio signal, whether a jam has occurred; and a control unit that stops paper transport when the audio jam determination unit determines that a jam has occurred. The control unit controls, in the case of card stock or paperboard being transported by the transport mechanism, so that the audio jam determination unit determines whether a jam has occurred at predetermined times using a determination method that is different than the method at other times or so that the audio jam determination unit does not determine whether a jam has occurred.
US09745156B2 Sheet feed cassette monitor that highly accurately detects open/close state of sheet feed cassette and presence/absence state of paper sheet, image forming apparatus, and sheet feed cassette monitoring method
A sheet feed cassette monitor includes an actuator with another end portion, a detecting circuit, a plurality of protrusions, a signal monitoring circuit, and a signal determining circuit. When the one end portion is in contact with a paper sheet, the other end portion swings in a first direction. When the one end portion is not in contact with the paper sheet, the other end portion swings in a second direction opposite direction to the first direction. The detecting circuit detects the swinging of the other end portion on the actuator. The plurality of protrusions are convexly installed in an asymmetric manner with respect to a putting-in/taking-out direction of the feed cassette. The signal determining circuit determines a presence/absence state of the paper sheet housed in the sheet feed cassette and an open/close state of the sheet feed cassette based on a pattern of change in the monitored signal.
US09745152B2 Impact buffer
An impact buffer has a retaining part for fitting to a loading ramp, a stop part for a vehicle to be loaded at the loading ramp to strike, and a buffer part for cushioning the stop part against the retaining part. The stop part is supported on the retaining part with at least one pivot lever.
US09745151B2 System and method for dispensing bulk material
A system for dispensing bulk material from storage is provided. The system comprises a plurality of stationary storage silos adapted to store the bulk material therein. A plurality of movable hoppers may be moveably positioned adjacent a bulk material chute of each storage silo to unload the bulk material therein. Once loaded with the bulk material, each movable hopper may then be positioned adjacent an input opening of a vehicle to unload the bulk material therein.
US09745146B2 Conveying device
The invention starts from a conveying device (10c) having at least one transport unit (20′c, 20″c) for transporting packaging blanks (12c) and/or containers (14′c, 14″c) in a transport direction (16c) along a transport path (18c), wherein the transport unit has at least one conveying element (24′c, 24″c) which can be driven along a section (22c) of the transport path (18c). It is proposed that at least one conveying element (24′c, 24″c) has a rear side (26′c, 26″c) which in at least one operating state is intended to pull packaging blanks (12c) and/or containers (14′c, 14″c) in the transport direction (16c), and a front side (28′c, 28″c) which in at least one operating state is intended to push packaging blanks (12c) and/or containers (14′c, 14″c) in the transport direction (16c). The invention also relates to a packing machine comprising such a conveying device.
US09745144B2 Divider arrangement for guiding packages between at least two conveyor belts, and method of controlling the same
A divider arrangement, guide device, for guiding packages between at least two conveyor belts, and method of controlling the same is provided.
US09745141B2 Method for addressing/sequencing linearly interlinked control components of a conveying system
Disclosed is a method for addressing/sequencing at least one control component (170 . . . 177) of a group comprising multiple control components (170 . . . 177) of a conveying system (1), said components being linearly interlinked via a daisy-chain selection line (23). The addressing process starts at any point in the chain and continues to the end of the respective branch of said chain. Subsequently, in one of the two branches the numbering of the control components (170 . . . 177) is reversed. Also disclosed is a conveying system (1) on which said method can be carried out.
US09745139B2 Device for the fast transport of objects
A device for the transport of singled objects comprising a first tube section, delimiting a loading channel from a rear aperture to a front aperture, a loading aperture for the insertion of the singled object in the loading channel, a second tube section connected to the rear aperture of the first tube section and delimiting a guide channel, a thrust generator suitable to generate in the loading channel a thrust in the transport direction, a transport support suitable to accommodate the object and arranged in the loading channel in such a way as to be launched in the transport direction along the guide channel and a rebound device positioned in the guide channel to make the transport support bounce, causing the release of the object from transport.
US09745134B1 Conveyor belt with rows of alternating types of bars
A conveyor belt comprised of a plurality of two types of elongated bars, arranged in parallel, spaced relation. The first type of bar includes a plurality of transverse elements, extending perpendicularly from either side of the bar. The second type of bar is preferably cylindrical. The two types of bars are arranged in alternating fashion along the belt, with the ends of the elements from the first type of bar in predetermined spaced relation from the side of an adjacent second type of bar. The relative heights of the two types of bars may be varied, to define article conveying pockets of different sizes and depths. Rollers are provided within of the arcuate ends of belts driving and supporting the bars. The belt may be endless, or assembled from one or more belt segments. Two or more belts may be combined laterally, to increase the width of the conveyor belt.
US09745129B2 Latching mechanism for a roll-out cart with lid
The present invention relates to a residential-sized waste disposal roll-out cart that includes a latch that automatically latches a lid in the fully opened position with the lid in close proximity to the side of the bin. When the bin is tilted on to the wheels to be rolled, the lid remains in close proximity to the side of the bin, rather than hanging down towards the ground. In this way, the lid remains out of the space where a user might step. A lid reinforcement structure may be used to increase the strength and wear of the lid where it engages the latch.
US09745126B1 Scented drawstring bag
The present invention is directed to a thermoplastic bag comprised of a front panel and a back panel. The front panel and back panel are generally joined along a first side edge, a second side edge, and a bottom edge of the respective front panel and back panel. The front panel has a distal edge with the distal edge folded over the front panel to provide a hem and an overlap area immediately below the first hem. The overlap encapsulates a scent carrier that provides a scent to the thermoplastic bag.
US09745124B2 Liquid containment system
System for preventing the leakage of liquid from an outdoor work-site around the perimeter of the work-site includes a load-supporting surface having at least two adjacent mats and a plurality of berm members configured to be disposed around the perimeter of the load-supporting surface.
US09745120B2 Beverage capsule for preparing a beverage by centrifugation in a beverage preparation device
Beverage capsule for preparing a beverage in a beverage preparation device from a capsule containing beverage ingredients by passing water through the ingredients contained in the capsule using centrifugal forces, said device comprising means for driving the capsule in rotation around an axis of rotation (I), a capsule holder for receiving the capsule and a water injection means for injecting water in the capsule, said device further comprising a valve means for engaging a valve engaging portion of the capsule; said valve means comprising a pressing ring; the capsule comprising a body and a lid and a valve engaging portion designed for being inserted between the capsule holder and the valve means of the device; wherein said capsule comprises an outlet structure forming beverage flow restriction passages of defined cross-section in the capsule at such and/or as a result of the insertion of the valve engaging portion between the capsule holder and the pressing ring of the valve means.
US09745119B2 Reticle pod
A dual containment pod having an outer pod and an inner pod that provides support structure and environmental control means. The inner pod includes a base having a flat, polished surface with protrusions upon which the reticle seats and providing a gap between the reticle and the polished surface. The gap separates the reticle from the flat, polished surface of the base and is dimensioned to inhibit migration of particles into the gap, thereby preventing contamination of sensitive surfaces of the wafer or reticle. The top cover of the inner pod seats on the polished surface proximate a periphery of the base. Moveable reticle engaging pins on the top cover of the inner pod are engaged by the top cover of the outer container when the inner pod is assembled inside the outer pod providing reticle restraint.
US09745118B2 Method of stabilizing a plastic aerosol container
A plastic aerosol container includes a main body portion that is constructed and arranged to withstand aerosol pressurization within a range that is about 50-300 psig. The plastic aerosol container also includes a finish portion that is unitary with the main body portion. The finish portion may be threaded or unthreaded. The finish portion has a side wall, an upper sealing surface, at least one helical thread and a support ledge beneath the helical thread. Reinforcement structure is positioned beneath the support ledge for reinforcing the finish portion against deformation due to the pressurization. A method of stabilizing a plastic aerosol container is also disclosed.
US09745117B2 Dispenser container comprising safety button structure
The present invention relates to a dispenser container comprising safety button structure. The dispenser container comprising safety button structure according to the present invention is designed such that a button member goes up and down, thereby allowing the contents to be discharged by pumping of a pumping member only when a rotating body is rotated, and thus it is possible to fundamentally prevent a button member from being pressed by children with poor cognition. Therefore, it is possible to prevent children from taking in harmful substances into the body and prevent unnecessary waste of contents.
US09745112B2 Dispensing bag having a hose spout
A flexible package having dispensing bag and a hose spout integrally coupled therewith. The dispensing bag is positioned within an outer vessel or urn having a valve dispensing member. The hose spout is extended through the valve dispensing member. The filled container can be emptied through the hose spout, which dispensing fluid flow can be controlled by the valve dispensing member. The hose spout comprises a molded member that includes a base flange that extends through a transition region to an elongated spout, with a dispensing opening at a distal end of the elongated spout.
US09745105B2 Water bottle
A portable, personal apparatus for transporting liquid having a bottle configured to contain liquid. The bottle has a longitudinal axis. A first opening open in a direction generally parallel with the longitudinal axis in a pour position. A first cover coupled to the bottle and configured to close the first opening in a closed position. A second opening open in a direction generally orthogonal with the longitudinal axis in a fill position. A second cover coupled to the bottle and configured to close the second opening in a storage position. The second cover remaining coupled to the bottle when the second cover is in the fill position.
US09745104B2 Flexible stackable package
A flexible, stackable, reclosable container for storing a quantity of products comprising a plurality of walls defined by a first sheet and a second sheet attached to at least a portion of the first sheet. The second sheet extends over at least three of the walls. The opposing container walls each have a sealed portion and one or more tucks, the tucks comprising a portion of the first sheet tucked toward the interior volume. A portion of the second sheet defines a reclosable feature located over an opening for reclosing the container. The second sheet includes a line of reduced strength at or adjacent at least a boundary adjacent the tucks and disposed between the opposing container walls each having the sealed portion and an adjacent container wall. The second sheet can include a hinge about which the reclosable feature pivots from closed position to open position.
US09745103B2 Wide mouth gusseted pouches
A reclosable gusseted bag is disclosed wherein a single web multiple alignment zipper is placed around the interior of the mouth of the bag, downwardly adjacent from the upper edge of the front panel, rear panel and side gussets thereby resulting in an increased size of opening as the mouth of the gusseted bag. The use of a single web multiple alignment zipper allows opposing portions of the web to engage each other within a range of alignments thereby allowing for simplified use by the consumer.
US09745102B2 Bag with handle
A bag has a front panel, a back panel, and a gusset, each having a thermoplastic ply at its interior face. The interior face of the gusset is thermally welded to the interior face of the front panel and back panel at respective joins from which extend respective panel extensions which are also thermally welded to each other at a third join. Extensions of the gusset cover parts of the respective panels and are thermally welded to them. Other parts of the panel extensions are not covered by the gusset extensions and are welded to each other to form the third join. The extensions can form a handle part for the bag.
US09745097B2 Pallet support block and a pallet constructed with pallet support blocks
A pallet support block is constructed of recycled plastic material that is also recyclable. The use of the pallet support block in pallet construction reduces the amount of wood used in the pallet construction and thereby makes the pallet lighter and reduces the cost of manufacturing the pallet.
US09745095B2 Container having a mini-petal-shaped bottom with transverse grooves
Container made of plastic material includes a body and a petal-shaped bottom (3) extending the body, the bottom (3) having a bottom wall (4) of general convex shape toward the outside of the container, from which feet (7) formed by protrusions project, separated two by two by portions of the bottom wall (4) forming recessed valleys (12) that extend radially to a periphery (8) of the bottom (3), the bottom (3) also including, in each valley (12), in the vicinity of the periphery (8) of the bottom (3), at least one groove (17, 18) that extends transversely relative to the radial direction of extension of the valley (12).
US09745088B2 Catheter tray, packaging system, instruction insert, and associated methods
A tray (100) for accommodating a coiled medical device, such as a catheter assembly (700), includes a first compartment (101), a second compartment (102), and a third compartment (103). The catheter assembly (700) and devices associated with a catheterization procedure, such as syringes (701,702) containing sterile water and lubricating jelly and a specimen container (703) can be disposed within the tray. Printed instructions (1001) can be included with the tray (100). One or more layers of wrap material (2200) can be folded about the tray (100) to enclose the tray (100) and other items, such as an additional layer of wrap material (2701), packaged liquid hand sanitizer (2401), and packaged gloves (2402). When a health care services provider (3101) unfolds the wrap material, the same can be used to create a sterile field beneath a patient (3201).
US09745086B2 Apparatus for supplying multiple foam machines with foam precursors
Apparatus for supplying multiple foam machines with foam precursor chemicals. The apparatus comprises first and second totes having a top opening and a bottom drain and containing first and second foam precursor chemicals, first and second supply lines connected to the bottom drains of the first and second totes and in fluid communication with first and second sets of batcher stands, and first and second sets of batcher pumps each of which is positioned in a respective one of the first and second sets of batcher stands. Each batcher pump is adapted to be in fluid communication with a respective one of the foam machines.
US09745084B2 Liquid medication dispensing machine
Provided is a liquid medication dispensing machine that can remove a liquid medication from one end of a supply pipe with higher reliability. The liquid medication dispensing machine includes a plurality of supply nozzles located at equal intervals through which liquid medications flow from a plurality of liquid medication bottles containing the liquid medications, respectively, to a prescription bottle. The plurality of supply nozzles are moved sequentially to a supply position where a supply nozzle faces an upper opening of the prescription bottle. The liquid medication dispensing machine further includes a cleaning unit that removes the liquid medication adhering to the supply nozzle. The supply nozzles are moved sequentially to a cleaning position where the cleaning unit removes the liquid medication from the supply nozzle. The cleaning position is provided at a position away from the supply position by a distance smaller than a spacing between the supply nozzles.
US09745081B2 Apparatus and method for moving a structure in a manufacturing environment
A mobile fixture configured to move a structure in a manufacturing environment may include a motorized base configured to move on a surface and a support system connected to the motorized base, the support system being configured to support the structure, the support system being configured to position the structure along at least one of an X-axis, a Y-axis, and a Z-axis, the support system being configured to position the structure about the Z-axis, and the support system being configured to provide free rotation of the structure about at least one of the X-axis and the Y-axis.
US09745075B2 Portable fuel storage device
A portable storage device to contain fuel, The device is designed to be relatively light-weight to allow for movement around a fueling facility, and to be delivered to the fueling facility through the air. The device includes a number of separate tanks each configured to contain fuel. A suspension protects the tanks by absorbing external forces that could occur in the event the device is dropped during air delivery.
US09745074B2 Aircraft propeller drive system
An aircraft propeller drive system has a gear to be driven by an engine and having a first plurality of teeth. A torsion bar has a first end driven by the gear and a second end rotatable relative to the first end about a torsion axis by a torsion angle. An output shaft is driven by the second end and is adapted for connection to a propeller. A clutch has a driven member rotationally fixed to the output shaft and a driving member having a second plurality of teeth. The first and second pluralities of teeth engage each other when a variation in the torsion angle from a mean torsion angle is greater than a predetermined angle. Torque is transferred between the gear and the output shaft via the clutch when the first and second pluralities of teeth engage each other.
US09745071B1 Ejectable flight data recorder systems, methods, and devices
An ejectable flight data recorder for robust retention of flight data and aiding in locating an aircraft after an emergency situation comprises: a buoyant housing comprising an internal cavity, a door for access to at least a portion of the internal cavity, and an aerodynamic outer shape having a longitudinal axis; an energy-dissipating nose cone for reducing an impact load on the housing when the flight data recorder impacts a water surface; a nonvolatile memory configured to store flight data; a position sensor for detecting a geographic position of the flight data recorder; a radio transmitter; an antenna electrically coupled to the radio transmitter; a sustainable power system; and a hydrophone for acoustically tracking a sinking trajectory of the aircraft in a body of water.
US09745070B2 Systems for multiple zone heaters for rotor craft and methods of operation
Within examples, systems for multiple zone heaters for rotor craft are provided and methods for operation. An example system for a rotor craft comprises multiple blades coupled to a rotor and areas of the multiple blades divided into sections. A given blade includes an inboard section extending from the rotor outward and an outboard section extending from the inboard section to a tip of the given blade. The system also includes a plurality of first spanwise heater systems included on respective outboard sections of the multiple blades, a plurality of second spanwise heater systems included on respective inboard sections of the multiple blades, and a control unit coupled to the plurality of first spanwise heater systems and the plurality of second spanwise heater systems. Respective heater systems of the sections of multiple blades are energized in a sequence based on outside air temperature.
US09745066B2 Adjustable seat assembly
A seat adjustment mechanism for an adjustable seat assembly includes an arcuate tilt column; a lift column; a first tilt slider block detachably engaged to the lift column and slideably engaged to the tilt column for moving the lift column between a plurality of tilt positions; and a first lift slider block slideably engaged to the lift column for moving between a plurality of lift positions independent of the plurality of tilt positions. The slider blocks, the lift columns, the tilt columns and the cross brace may be made of dissimilar materials and/or are easily replaced with alternative components.
US09745061B2 Propulsion devices with improved controls
A personal propulsion device adapted to achieve flight by discharging a fluid, including a passenger assembly adapted to support an individual person; at least one fluid discharge nozzle coupled to the passenger assembly, where the nozzle is movable with respect to the passenger assembly to define a range of motion, and where the nozzle is biased towards at least one position in the range of motion.
US09745056B2 Main rotor blade with composite integral skin and cuff
A main rotor blade assembly is provided including a spar which comprises a main section. A main core is positioned adjacent a trailing side of the main section of the spar. A tip assembly includes a main tip core and a tip end pocket core. The tip assembly is positioned adjacent an outboard end of the main core and the spar such that the main tip core is substantially aligned with a longitudinal axis of the main core and the tip end pocket core is substantially aligned with a longitudinal axis of the spar. At least a portion of both the main tip core and the tip end pocket core comprises a high density core. An upper composite skin and a lower composite skin extend over the spar, the main core, the main tip core, and the tip end pocket core. A portion of the upper composite skin and the lower composite skin has a thickness sufficient to be load bearing.
US09745055B2 Active vibration isolation with direct fluid actuation
A method of isolating vibrations between vibrating bodies includes determining a pressure differential between a first fluid chamber and a second fluid chamber of a liquid inertia vibration eliminator (LIVE) unit, and selectively injecting fluid into or withdrawing fluid from the LIVE unit based on the pressure differential. A system for isolating vibrations between bodies includes a vibration isolator including fluid, a fluid regulator valve in fluid communication with the vibration isolator to selectively flow fluid through the vibration isolator, a pressurized fluid source in fluid communication with the fluid regulator to supply fluid to the fluid regulator, a controller in signal communication with the fluid regulator to control fluid flow between the fluid regulation valve and the vibration isolator, and at least one sensor in signal communication with the controller.
US09745049B2 Seal assembly
A seal assembly for closing an aperture in an aerodynamic surface of a structure, the seal assembly comprising: a track for attachment to the structure; and a retractable seal including a flexible substrate and a plurality of rods connected to the substrate, wherein at least one of the rods is mounted for running movement along the track, and the seal is moveable between an extended position and a retracted position by moving the at least one rod along the track accompanied by folding/unfolding of the seal substrate, and wherein the seal is biased to its extended position.
US09745045B2 Door stop element for an aircraft door
A door stop element for an aircraft door has a body which is formed at least approximately L-shaped, and which has at least one contact area on the outer side of one of the legs for fixed contact on the aircraft fuselage, and a stop surface on the inner side of the other leg for the aircraft door. The body has a cavity, on the inner side of which adjacent to the stop surface a rib is provided, which extends through the stop surface symmetrically on both sides of the longitudinal median plane that extends perpendicular to the stop surface.
US09745044B2 Aircraft including a support deployable outside the fuselage
An aircraft including a fuselage with a skin in which is made an opening, the skin delimiting the interior and the exterior of the fuselage. A closure panel is mobile between a closed position in which the panel covers the opening and an open position in which the closure panel uncovers the opening. A support including a base is fastened to the fuselage. At least one bar and an articulation between the bar and the base allow the bar to occupy a position retracted inside the fuselage and a deployed position outside the fuselage. The articulation is a pivoting connection.
US09745039B2 Outboard motor
An outboard motor includes an engine, a power generator including a rotor and a stator, a convertor, and an engine cover configured to cover the engine and the power generator. The rotor includes a permanent magnet.
US09745038B2 DC power system for marine applications
A power system for a marine ship includes a plurality of protection zones, wherein at least two protection zones are coupled to each other via at least one bus-tie converter. Each of the protection zones includes a plurality of direct current (DC) buses; wherein DC buses which do not have same DC voltage are coupled to each other via at least one DC to DC converter. Furthermore, at least one energy source is coupled to at least one DC bus via a power electronic converter.
US09745035B2 Control apparatus for outboard motor
In an apparatus for controlling an outboard motor mounted on a boat and having an internal combustion engine and a variable pitch propeller, characteristics defining a desired pitch angle of the propeller that makes fuel consumption minimum relative to a navigation speed of the boat are memorized and the pitch angle of the propeller is controlled to the desired pitch angle that is corresponding to the navigation speed detected by a navigation speed detector in accordance with the characteristics.
US09745031B2 Fin stabilizer and watercraft
A fin stabilizer for stabilizing a watercraft against rolling movements includes a main fin configured to be pivoted by a watercraft-side fin drive, a tail fin, and an elastically deformable connection between the main fin and the tail fin, the elastically deformable connection being configured to flex whenever a water force acting on the tail fin is greater than a predetermined amount.
US09745029B1 Oxygen tank flotation device
The oxygen tank flotation device is a floating structure adapted for use in recreational water activities. The oxygen tank flotation device is adapted for use with respiratory equipment that is required for use during recreational water activities. The oxygen tank flotation device receives and stores respiratory equipment, such as an oxygen tank, in such a manner that the respiratory equipment will float when the oxygen tank flotation device is placed in a body of water. This arrangement allows the respiratory equipment to float near the user when the user is involved in recreational water activities. The oxygen tank flotation device comprises a vessel, a first float, and a second float.
US09745028B2 Stern transom and seating of a collapsible boat hull
A collapsible boat hull (10) with at least one bottom panel (16,18) and two side panels (12,14), and a removable transom (32) with attachment means (36) to engage the transom with the two sides of the boat hull, such that, during installation of the transom member, the attachment means initially engages with the sides of the boat, and rotation of the transom to an upright position in the boat hull retains the attachment means and the respective sides of the boat hull together. Releasable latches (42,44) at the lower edge of the transom engage with retaining members (54) on the bottom panels. Seating or cross-bracing has (100) which releasably engage with retainers on the sides of the boat.
US09745019B2 Battery container and bicycle using the same
A battery system assembly for a bicycle is provided. The battery system assembly includes a frame cavity liner, a first cover slideably attached to the frame cavity liner and movable between a first position and a second position with respect to the frame cavity liner, a first magnet interposed between the frame cavity liner and the first cover, a battery container configured to accommodate a rechargeable battery and having a second magnet disposed to face the first magnet, said battery container detachably attached to the frame cavity liner. When the first cover is located at the first position, the frame cavity liner and the battery container are attached one another by magnetic force between an aligned first magnet and second magnet. When the first cover is located at the second position, the first magnet and the second magnet repel each other, thereby detaching the battery container from the frame cavity liner.
US09745014B2 Operating device of straddle type vehicle
An operating device of a straddle type vehicle has a controller for selecting a plurality of function menus of components mounted on the straddle type vehicle. Controller supporting portions support the controller, and are disposed in the front direction of a switch box. The controller has a controller operating portion which a rider can operate. The controller operating portion is positioned in the front direction of a grip portion.
US09745012B2 Vehicle
A vehicle includes a linkage, a steering force transmission, and a steering lock. The steering force transmission includes a rear shaft that is able to turn about a rear axis, a front shaft that is able to turn about a front axis, and a connector. When seen from a side of the vehicle, a distance between the front shaft and a right steering axis is smaller than a distance between the rear shaft and the right steering axis, and in which at least one portion of the steering lock that is mounted on the front shaft or a member that turns together with the front shaft and a member that is displaced relative thereto is provided in a position that overlaps a movable range of the linkage when seen from the side of the vehicle.
US09745011B2 Assembly composed of a saddle and a saddle compartment for motorcycles
An assembly composed of a saddle (10) and of a saddle compartment (12) for a motorcycle is described. The saddle (10) comprises an upper padded portion which constitutes the seat for the rider and/or passenger of the motorcycle, and a substantially rigid bottom portion (14) operatively connected to the relative saddle compartment (12) by hinge means (16). The saddle compartment (12) is made integral with a fixed portion of the motorcycle. The hinge means (16) enable the saddle (10) to pass from a closed position, in which said saddle (10) is positioned substantially horizontally above the saddle compartment (12) and permits the rider and any passenger of the motorcycle to sit on it, and an open position, in which said saddle (10) is positioned in a substantially vertical position and permits access to the saddle compartment (12). The assembly comprises at least one gas spring (18) attached to a fixed portion of the motorcycle and operatively connected, at its upper end, to the saddle (10). Between the upper end of the gas spring and the saddle (10) articulated connection means (20, 22) are interposed which permit said saddle (10) to maintain a stable open position.
US09745010B2 Lightweight bicycle seat assemblies
A bicycle seat apparatus including at least one rail and a saddle shell. The at least one rail can include a first mounting portion. The first mounting portion can include an ankle. A cross section of a terminus of the ankle can be larger than a cross section of the at least one rail. The saddle shell can include at least one mounting cup configured to mate with the first mounting portion of the at least one rail. A cross section of a base of the at least one mounting cup can be larger than a cross section of the terminus of the ankle.
US09745006B2 Upright receiver assembly for attachment to trailer and methods of use
Upright receiver assemblies for attaching to trailers and acting as hitches are disclosed herein. The upright receiver assemblies include (a) an upright and (b) a base, both pieces being releasably attachable to each other. The upright contains a vertical post have a top positioned receiver while the base includes a center plate, two cross bars, and two angled side plates.
US09745004B2 Inverted vehicle and control method thereof
An inverted vehicle and control method thereof are provided. The inverted vehicle may include a main body having two wheels rotatably supported by the main body and driven by a driver. A load distribution detector may detect a distribution of load received by the main body due to the rider's weight. A computer may compute a center position of the load's distribution. The inverted vehicle may also include an operating bar supported by the main body and operated so as to be inclined by the rider. A posture detector may be used to detect a posture of the operating bar. The inverted vehicle may further include a central processing unit that sets a target travel velocity on the basis of the center position and the posture of the operating bar. Furthermore, a drive controller may control the driver on the basis of the target travel velocity.
US09744998B2 Vehicle body reinforcing structure
A first reinforcing reinforcement that is formed of a fiber reinforced resin material is continuously superposed with and adhered to an inner wall surface of a front wall portion, an inner wall surface of an outer wall portion, and an inner wall surface of a rear wall portion of an outer reinforcement. A pair of superposed portions of a second reinforcing reinforcement are superposed, via the first reinforcing reinforcement, with the inner wall surface of the front wall portion and the inner wall surface of the rear wall portion of the outer reinforcement. The second reinforcing reinforcement is directly joined to the front wall portion and the rear wall portion of the outer reinforcement, and the pair of superposed portions are connected by a connecting portion.
US09744997B2 B-pillar and method of manufacturing it
A B-pillar is shaped from a sheet blank (20,21) into a hat profile with a central flange (12), two sides (13,14) and two side flanges (15,16), and it has, over a portion of its length, a reinforcing sheet (21) that make the B-pillar have double sheets. The reinforcing sheet (21) extends out over the side flanges (15,16) over at least ¼ of its length and narrows down at both its ends so that it does not extend out over the side flanges over part of its length.
US09744996B2 Vehicle front structure
A vehicle front structure including: a front side member in a side part of a vehicle that extends in a longitudinal direction; apron upper member above the front side member; and apron lower member that bridges between the upper member and a front end portion of the front side member. The lower member includes: a first end portion fixedly attached to the upper member and extending toward the front of the vehicle; an upper bent portion bent toward the bottom from the first end portion; an intermediate joint portion extending linearly from the upper bent portion toward the bottom; a lower bent portion bent toward the front from the intermediate joint portion, and the lower bent portion including a second end portion that is provided by a distal end portion of the lower bent portion, the second portion being fixedly attached to the front portion of the first side member.
US09744992B2 Fault tolerant apparatus for an independent controlled steering in a four wheel system
The following description relates to a fault tolerant apparatus for an independent controlled steering in a four wheel system, particularly a fault tolerant apparatus for an independent controlled steering in a four wheel system which can stabilizes a vehicle body through actively adjusting a steering angle of a vehicle and a velocity of a vehicle according to a breakdown environment and a vehicle driving road environment. Further, a fault tolerant apparatus for an independent controlled steering in a four wheel system that may assist a safe driving environment by adjusting a turning function adoptively to a surrounding road environment.
US09744990B2 Hydraulic steering system
A hydraulic steering system 1 is described comprising a steering unit and a priority valve, said steering unit comprising a working port arrangement having two working ports, a supply port arrangement having a high pressure port and a low pressure port, a load sensing port, a main flow path having a main bleed and a metering device and being arranged between said high pressure port and said working port arrangement, an amplification flow path having an amplification bleed and being arranged between said high pressure port and said working port arrangement, said main bleed and said amplification bleed being controlled together by means of a steering handle and being closed in neutral position of said steering handle, wherein said priority valve comprises a priority outlet connected to said high pressure port of said steering unit, a valve element moveable in a priority direction to connect an inlet of said priority valve to said priority outlet, and a load sensing connection connected to said load sensing port of said steering unit, said priority outlet being connected to said load sensing connection via a priority valve bleed, a pressure at a point downstream said priority bleed acting on said valve element in said priority direction, wherein said load sensing port is connected to said low pressure port via a drain bleed being open in neutral position of said steering handle and closing upon actuation of said steering handle out of said neutral position.
US09744987B2 Worm shaft subassembly
According to one exemplary embodiment of the present invention a worm shaft subassembly for supporting a worm shaft is provided. The worm shaft has a worm shaft radial load, a worm shaft axial load, and a worm shaft axial travel. The worm shaft subassembly includes at least one damping member to support the worm shaft axial load. The at least one damping member has at least one damping member axial load. The at least one damping member limits the worm shaft axial travel. The worm shaft subassembly also includes a bearing to support the worm shaft radial load and the at least one damping member axial load.
US09744986B2 Steering arrangement
A steering arrangement including a first, second, third and fourth hydraulic chamber, the first and third chambers being operable to steer in a first direction and the second and fourth chambers being operable to steer in a second direction. A pump system supplies fluid to a steering system, which is operable to supply the pressurized fluid to one or more of the first, second, third and fourth hydraulic chambers. The steering system having a first mode wherein fluid is supplied to the first and third hydraulic chambers to steer in the first direction, or pressurized fluid is supplied to the second and fourth hydraulic chambers to steer in the second direction. The steering system having a second mode to steer in the first direction, or to steer in the second direction, such that the steering ratio is higher in the second mode than in the first mode.
US09744985B2 Rack bar unit of vehicle steering device
A rack bar unit of a vehicle steering device may include a rack bar body and a rack gear made of different materials, in which the rack gear may be coupled to the rack bar body.
US09744980B2 Methods and systems for controlling engine operation through data-sharing among vehicles
Various embodiments of methods and systems are provided for enhancing engine operation through data-sharing among vehicles. In one embodiment, a method includes determining whether a first value of a first operating parameter produced by a first vehicle is corrupted or unavailable; receiving a second value of the first operating parameter produced by a second vehicle that is proximate to the first vehicle; adjusting the second value by a first adjustment factor, the first adjustment factor based on a first value of a global positioning system (GPS) position of the first vehicle produced by the first vehicle and a second value of a GPS position of the second vehicle produced by the second vehicle; and in response to determining that the first value is corrupted or unavailable, controlling operation of an engine of the first vehicle based on the adjusted second value of the first operating parameter.
US09744977B2 Method to inspect and correct railcar brake shoe alignment
A method to inspect and compensate for wear on a brake shoe of a railcar brake system includes removing the railcar brake shoe from a brake head of the railcar brake system, placing a brake inspection device between the brake head and a railcar wheel, applying brake load, measuring a gap formed between the brake head and the wheel, measuring the thickness of a stop block of the brake inspection device positioned between the brake head and the railcar wheel, determining an adjustment distance as the difference between the gap measurement and the thickness of the stop block, and adjusting an end extension of the railcar brake system in accordance to the determined adjustment distance.
US09744976B2 Railway vehicle and axle box structure thereof
A railway vehicle and an axle box structure thereof are provided. The axle box structure includes an axle box body and a positioning joint mounting seat, and a bearing mounting cavity is provided inside the axle box body. The positioning joint mounting seat is provided with a mounting cavity configured to mount a positioning joint, a longitudinal center line of the axle box body is in parallel with a longitudinal center plane of the positioning joint mounting seat, and the longitudinal center plane of the positioning joint mounting seat is outwardly deviated with respect to a longitudinal center plane of the axle box body. In this way, a large space can be left for mounting the brake clamp, and the mounting and replacing of the brake clamp and the wheel set can be facilitated.
US09744974B2 Vehicle driver-model controller with energy economy rating adjustments
A controller with energy economy rating (EER) calibration logic is configured to adjust a look-ahead time and feed-forward mapping window for vehicle controls according to EER.
US09744972B2 Trailer backup aid speed limiting via braking
A trailer backup assist system for a vehicle reversing a trailer includes a brake system and a throttle sensor module outputting a throttle application signal. The system further includes a control module estimating a road grade beneath the trailer and outputting a brake torque request to the brake system based on the estimated road grade and the throttle application signal.
US09744970B2 Estimating a trailer road grade
An example trailer road grade estimating method includes calculating a road grade beneath a trailer vehicle based on a difference between a first estimated mass and a second estimated mass.
US09744966B2 Startup control device and startup control method for hybrid vehicle
A startup control device includes a vehicle temperature sensor configured to sense a temperature of the vehicle, a vehicle startup controller configured to select the second vehicle startup mode in a low temperature state in which the temperature of the vehicle is equal to or smaller than at least a first temperature judgment value when the request of the startup of the vehicle is sensed, and to select the third vehicle startup mode in an extremely low temperature state in which the temperature of the vehicle is equal to or smaller than a second vehicle temperature judgment value which is smaller than the first temperature judgment value when the request of the startup of the vehicle is sensed.
US09744962B2 Hybrid construction machine
The hybrid construction machine includes an engine 11, an electric motor/generator 14, a hydraulic pump unit 17, an electricity storage device 16, an inverter 15, a temperature regulator (16D or 16E), and a hybrid control unit 22. The hybrid control unit 22 executes at least one of first control for controlling a warming-up battery temperature regulator 16D so that it increases a temperature of the electricity storage device 16, second control for controlling the inverter 15 so that it reduces the power output from the inverter 15, and third control for controlling a pump capacity control unit 21 so that it reduces the flow rate of a hydraulic fluid delivered from the hydraulic pump unit 17, according to a charge/discharge history of the electricity storage device 16.
US09744960B2 Control system for a plug-in hybrid vehicle
A control system for a plug-in hybrid vehicle has a drive system having a starter motor, a transverse engine, and a motor/generator, and also has a power supply system having a high voltage battery; a capacitor; and a hybrid control module that controls charge and discharge of the capacitor. In the control system for an FF plug-in hybrid vehicle in which external charging of the high voltage battery is available, the hybrid control module starts the starter, performs a mode selection control and a charge/discharge control, maintains the capacitor voltage equal to or higher than a voltage that allows the starter to start-up when a CD mode is selected at the time of ignition ON, and maintains a capacitor voltage equal to or less than a voltage at which deterioration does not proceed at the time of ignition ON with the CS being selected.
US09744959B2 Adjusting motor torque to enable slip of torque converter clutch to be maintained when accelerator pedal released in hybrid vehicle
A controller and a control strategy for a hybrid electric vehicle having a traction motor between an engine and an automatic transmission include maintaining a bypass clutch of a torque converter in an engaged position and applying a motor torque from a traction motor to the torque converter such that slip of the torque converter does not otherwise reach zero while the bypass clutch is maintained in the engaged position.
US09744955B1 Towbar activated brake system having differential rotation capability
A tow bar-activated brake system capable of engaging two tires or tire sets of a dolly or trailer where the tires or tire sets are of substantially different diameter. The system includes a first brake assembly and second brake assembly commonly actuated yet capable of rotating independently of each other to provide engagement with both tires/tire sets, even when the tires/tire sets are of substantially different diameter, for example due to uneven wear.
US09744954B2 Brake actuation system
A brake actuation system of a hydraulic brake system, for actuating at least one front axle brake circuit having at least one front wheel brake, and for actuating at least one rear axle brake circuit having at least one rear wheel brake, the brake actuation system including at least one hand brake module which, when actuated, can activate both brake circuits. In order to provide an improved brake actuation system with a plurality of actuation capabilities, which system can also be utilized in light motorcycles and scooters without the restrictions of existing brake actuation systems, while simultaneously offering a simple concept and a reduced cost and weight, the hand brake module is hydraulically coupled into a combined hand brake module, the combined hand brake module being designed to simultaneously generate brake pressure in both brake circuits.
US09744952B2 Brake system and vehicle
A brake system includes a brake activator which reduces, when a slipping condition of a right front wheel is detected based on a signal which is detected by a right detector, both braking forces on the right front wheel and a left front wheel to a lower level than a level of a braking force which is obtained as a result of operation of an input member and which reduces, when a slipping condition of the left front wheel is detected based on a signal which is detected by a left detector, both braking forces on the left front wheel and the right front wheel to a lower level than a level of a braking force which is obtained as a result of operation of the input member.
US09744948B2 Windscreen wiper
The present invention relates to a windscreen wiper (1) for a motor vehicle window (3), comprising: a longitudinally extending wiper blade (5), an aerodynamic deflector (9) extending longitudinally above said wiper blade (5), at least one longitudinally extending fluid circulation duct (31, 32) having at least one spraying orifice (35), characterized in that the wiper comprises at least one lower lateral skirt (43, 44) extending longitudinally on a lateral side of the wiper blade (5) and of the spraying orifice (35), the spraying orifice (35) being located between the wiper blade (5) and the lower lateral skirt (43, 44).
US09744947B2 Connector between a wiper blade and a drive arm
The invention relates to a connector (1) for a windscreen-wiper blade (2), said connector (1) being configured such as to engage with an adapter (3) for enabling a connection between said blade (2) and a drive arm, said connector (1) including a body (10) and a cover (30) which is movable on said body (10) along a hinge axis (X), said cover (30) including at least one means (31) for hinging on said body (10) and at least one first slot (32), said one or more first slots (32) being located on one or more side portions (33) of said cover (30) such as to form flexible areas (42), said one or more flexible areas (42) including the one or more hinging means (31). The invention also relates to an attachment device including an adapter (3) and a connector (1) such as previously described. The invention further relates to a windscreen-wiper blade (2) including such an attachment device. The invention finally relates to a wiping system including such a windscreen-wiper blade.
US09744940B1 Seatbelt pretensioning retractor assembly
A seatbelt pretensioning retractor assembly for use in a passenger vehicle is provided. The pretensioning assembly includes a tube in fluid communication with a gas generator and a driving element disposed therein that travels in a first direction in response to actuation of the gas generator. The driving element includes a plastically deformable polymer rod with a recessed portion. A stopper is coupled to an end portion of the plastically deformable polymer rod. A seal member is disposed between the gas generator and the stopper. The tube includes a projection extending within the tube adjacent to the exit to define a constriction portion. The constriction portion is sized to permit the recessed portion of the plastically deformable polymer rod to pass therethrough while preventing the stopper from passing therethrough.
US09744937B1 Vehicle pet harness
The present invention is an improved safety harness for animals riding in a motor vehicle, wherein the harness prevents or greatly reduces the chance of the animal's lower quarters from being forced under the animal's head and shoulders, reduces the amount of rotational movement, reduces the side to side movement, reduces the chance for the dog to be forced off the car seat and reduces the amount of head excursion during a vehicle crash or a sudden stop.
US09744936B2 Curtain airbag for a vehicle and a restraining arrangement
A curtain airbag for a vehicle has a main chamber shaped in the position being mounted on the vehicle, in the inflated state covering an inner side structure of the vehicle. The curtain airbag has an additional chamber which, in the mounting position, is located at the in driving direction of the vehicle front portion of the main chamber, and deploys in the direction of the interior of the vehicle when the curtain airbag is inflated. The additional chamber is attached to the main chamber so as to be positioned in the inflated state between the front portion of the main chamber and an occupant to be restrained by the curtain airbag.
US09744927B2 Generating electricity from air resistance caused by a moving vehicle
A system for generating electricity is provided. The system includes a vehicle and a wind turbine installed at one end of the vehicle. The wind turbine includes a plurality of input ports and a plurality of exit ports. The airflow around the vehicle enters the wind turbine via the plurality of input ports and exits the wind turbine via the plurality of exit ports causing the wind turbine to rotate and generate electricity.
US09744921B2 Engine hood
Provided is an engine hood comprising: an outer panel that constitutes an outer part of the engine hood; and an inner panel that constitutes an inner part of the engine hood and that is joined to the outer panel such that a space is formed between the inner panel and the outer panel. A porous section that comprises a plurality of through holes is provided to the inner panel. An external air intake hole that guides external air into the space is provided to the engine hood.
US09744918B2 Vehicle decoration structure
A vehicle decoration structure for decorating a design surface (25a) in a cabin (11) is such that on the design surface (25a), there is formed a first decoration layer (31) with a first pattern (31a) that is visually recognizable with natural light. In a part of an upper surface of the first decoration layer (31), a light-accumulating material (32) having light-accumulating property and shaped in a second pattern is disposed. On upper surface of the first decoration layer (31) and the light-accumulating material (32), a second decoration layer (33) having a fluorescence pattern (33a) is formed using a fluorescence paint having no light-accumulating property.
US09744915B2 Travel control device and travel control method
A travel control device includes ultrasonic obstacle detection sensors detecting an obstacle entering a rear side of a vehicle and a distance to the obstacle, and an image obstacle detection unit detecting the obstacle entering the rear side of the vehicle by using an image of the rear side. If a distance to the obstacle detected by the sensors is equal to or less than an activation threshold for warning, the travel control device issues a warning, and sets the activation threshold larger as the vehicle speed of the vehicle becomes high. If the vehicle is detected preparing to move rearward and the image obstacle detection unit detects the obstacle, the travel control device sets the activation threshold to a constant value regardless of the vehicle speed.
US09744913B2 Systems and methods for a mountable electronic device holder
A system for holding an electronic device includes a body and a connection device for connecting an electronic device to the body, at least a portion of the connection device attached to the body. The system further includes a clip, the clip having a top portion and a bottom portion, the clip attached to the body. The system further includes a cam lever, the cam lever oriented in the body and in communication with the clip, the cam lever having a first position and a second position, the first position characterized by the cam lever not engaging the clip, the second position characterized by the cam lever engaging the clip, and causing the top and bottom portion of the clip to be pushed together.
US09744910B2 Foldable load carrier with a latching brace
A cargo load carrier configured to be mounted at the rear of a carrying vehicle and having a support frame mountable to the vehicle. A load carrying member is coupled to the support frame and is deployable from an undeployed configuration to a deployed configuration. A collapsible brace is coupled between the support frame and the load carrying member and has an articulated joint between a pair of pivot arms. A latch is releasably coupled between the pair of pivot arms and the latch has a plurality of latched configurations that releasably lock the load carrier in at least the travelling configuration and the load supporting configuration.
US09744901B2 Vehicle-mounted apparatus
An apparatus mountable on a vehicle includes a movable device, a sensor, and a drive controller. The movable device is mountable on the vehicle so that a person around the vehicle sees the movable device. The movable device has at least one light emitter and is capable of rotating around an imaginary line extending in a height direction of the vehicle. The sensor detects a positional relationship between the vehicle and the person. The drive controller rotates the movable device toward the person based on the positional relationship detected by the sensor. The number of the light emitters shining steadily is increased after the drive controller rotates the movable device toward the person.
US09744898B2 Securing assembly
A securing assembly is adapted to secure objects to a structure. The assembly includes an attachment mechanism adapted to attach the assembly to an object in use. An elongate rod has a first end and a second end, wherein the first end is connectable to the attachment mechanism and the second end is connectable to an adjustment device. A base is adapted to connect the adjustment device to the structure in use. The adjustment device is operable to adjust a tension between the object and the structure by way of the assembly to secure the object to the structure in use.
US09744894B2 Adjustable footrest assembly
Footrest assembly for a passenger seat having a saddle (22) and a post (16) pivotally coupled to a fastener (38) connected to the saddle. A ratcheting mechanism (86) with at least one tooth (88) is positioned on a first end (20) of the post and a pawl (90) is pivotally coupled to a pawl shaft (98) fixedly coupled to the saddle. A cam follower (96) is pivotally coupled to the fastener and positioned within a slot (106) formed in the end of the post in order to prevent the pawl from engaging with a tooth while pivoting in a direction of a fully deployed position of the assembly.
US09744893B2 Vehicle seat
A vehicle seat includes a bracket, a frame on which the bracket is installed, and a fixing member that is used for fixing the bracket and the frame. The bracket is provided with an engaging portion, the frame is provided with an engaged portion that is engageable with the engaging portion. By installing the fixing member to fix the bracket and the frame to each other, a state where at least a part of the engaging portion is inserted into the engaged portion or a state where at least a part of the engaged portion is inserted into the engaging portion is maintained while the bracket is elastically deformed.
US09744890B2 Vehicle seat
A vehicle seat including a seat pad including a flow channel portion, a seat cover covering the seat pad and having breathability, a functional member disposed between the seat pad and the seat cover and having breathability, and a blowing member configured to blow the gas into or out of the seat through the flow channel portion of the seat pad and the seat cover along a flow path, wherein the functional member is integrated with any one of the seat pad and the seat cover with an adhesive portion, which has poorer breathability than the seat cover and the functional member, interposed therebetween, and wherein the adhesive portion includes a passage portion through which the gas is configured to pass, and the passage portion is disposed in the flow path of the gas.
US09744889B2 Vehicle air-conditioning system provided with seat air-conditioning unit
An air-conditioning system includes a vehicle air-conditioner which uses a target blowing-out temperature as the basis to control an air outlet temperature in a cabin and a seat air-conditioning unit which sucks recirculated air into a seat. The air-conditioning system controls at least the seat air-conditioning air flow per unit time so as to perform seat air-conditioning. The air-conditioning system increases the seat air-conditioning air flow when detecting that the vehicle speed is stopped or idling, calculates a correction amount for the target blowing-out temperature considered neutral in warmness sense level for the increased seat air-conditioning air flow, and uses the correction amount as the basis to correct the target blowing-out temperature.
US09744888B1 Integrated cooling system for an adjustable headrest assembly
A headrest assembly is removeably supported on a vehicle seat having a seatback with a seatback frame. The headrest assembly includes a headrest bun operably coupled to a housing via a powered linkage system for driving the headrest bun between extended and retracted positions. A temperature control system is disposed in the housing and configured to provide treated air to a conditioning area disposed below the headrest bun at a vehicle occupant's neck. The temperature control system includes a blower operably coupled to duct assembly for blowing air treated by a thermoelectric module along the duct assembly. One or more vents are disposed at a downward angle on a front portion of the housing. The one or more vents are operably coupled to and in communication with the duct assembly.
US09744882B2 Two-axis seat hinge
A movable seat for a motor vehicle includes a base fixedly attached to a frame of the motor vehicle, a seat frame having a top side and a bottom side, and a seat cushion fixedly attached to the top side of the seat frame. A U-shaped hinge connects the seat frame to the base, a first end of the first U-shaped hinge being rotatably attached to the base and rotating about a first lateral axis, and a second end of the U-shaped hinge being rotatably attached to the seat frame and rotating about a second lateral axis. A wire that connects a first electrical appliance in the seat cushion to a second electrical appliance is included that is attached to the U-shaped hinge from the first end to the second end.
US09744874B2 Electric vehicle and control method for electric vehicle
An electric vehicle includes: a vehicle drive apparatus configured to receive electricity to generate vehicle drive power and to generate electricity; a secondary battery that selectively receives and outputs electricity from/to the vehicle drive apparatus; a current sensor that selectively detects (a) an electric current to be input into the secondary battery and (b) an electric current output from the secondary battery; and an electronic control unit configured to control charging and discharging of the secondary battery, and configured to calculate, using a detected value from the current sensor, an evaluation value indicating a degree of deterioration of the secondary battery due to non-uniformity in salt concentration in the secondary battery caused by charging and discharging of the secondary battery. The electronic control unit is configured to execute a capacity-raising control in which a remaining capacity of the secondary battery is raised when the evaluation value reaches a prescribed threshold.
US09744871B2 Automotive recharge scheduling systems and methods
An apparatus includes a processor configured to receive an input signal corresponding to a selected charging station. The processor is further configured to select an electrical charge allocation from an available power budget of the selected charging station in response to the input signal.
US09744869B2 Electric power supply system, vehicle and method of operating a vehicle
Disclosed is an electric power supply system, vehicle and method of operating a vehicle, wherein an electrical power supply system, in particular a traction system, of a vehicle, includes an energy storage module, an inverter, an electric machine, a receiving device adapted to receive an alternating electromagnetic field and to produce an alternating electric current by electromagnetic induction, and a passive electric circuit arrangement adapted to connect the inverter, the electric machine, and the receiving device, wherein the passive electric circuit arrangement includes a first transmission circuit for transferring electric energy between the receiving device and the electric machine, a second transmission circuit for transferring electric energy between the receiving device and the inverter, and a third transmission circuit for transferring electric energy between the inverter and the electric machine, wherein the passive electric circuit arrangement is designed such that at a given charging frequency, an impedance provided by the first transmission circuit is higher than a predetermined first blocking impedance and an impedance provided by the second transmission circuit is lower than a predetermined second passing impedance.
US09744862B2 Slip-controlled braking system for electrically driven motor vehicles
A braking system for a motor vehicle, including friction brakes on the wheels of at least one axle, the brakes controlled by a friction brake control device; at least one electric machine connected to at least one wheel and controlled by an electric drive control device; a brake pedal for detecting a deceleration request; a wheel-slip controlling device; and a torque distributing device. The devices for detecting a deceleration request are connected to the wheel-slip controlling device, the wheel-slip controlling device specifying target braking torques for each wheel according to the parameters of the deceleration request. The wheel-slip controlling device connected to a torque distributing device which is connected to the friction brake control device and the electric drive control device and which specifies friction brake requests to the friction brake control device and generator brake requests to the electric drive control device according to the target braking torques.
US09744861B2 Power conversion device
Even in the case in which an overvoltage is generated when a vehicle is in a non-operation state, the overvoltage can be suppressed. A power conversion device is connected to a three-phase motor mounted on a vehicle and includes an inverter circuit, a gate drive substrate, and a motor control substrate. In the motor control substrate, when the vehicle is in the non-operation state and a regenerative voltage applied from the three-phase motor to the inverter circuit becomes equal to or more than a predetermined threshold value, a power supply circuit supplies operation power to a control circuit. The control circuit starts when the operation power is supplied from the power supply circuit and outputs gate control signals to a driver circuit of the gate drive substrate, such that regenerative energy according to the regenerative voltage is consumed between the three-phase motor and the inverter circuit.
US09744857B2 Electric charging method for a vehicle and electric vehicle charging device
A system and method for charging a vehicle having a first battery, such as a high-voltage traction battery, and a second battery, such as a low-voltage battery, include controlling a DC converter or relay to effectively decouple the second battery from the converter when the vehicle is connected to an external power source to reduce or prevent damage to the second battery from extended or prolonged charging. The second battery may be effectively decoupled from the converter by controlling the relay or converter voltage based on state of charge of the second battery so that substantially zero current flows to and from the second battery relative to the converter and any vehicle low voltage consumers/accessories.
US09744852B2 Integration of add-on interior modules into driver user interface
A listing of wireless in-vehicle components installed to a vehicle may be maintained by the vehicle. The listing may include in-vehicle components that are factory-installed to the vehicle as well as add-on in-vehicle components that may be added or removed by a user. A wireless transceiver may scan for changes to the add-on in-vehicle components within the vehicle. A user interface may display a unified interface including both the factory-installed wireless in-vehicle components and the add-on wireless in-vehicle components. A user may review and adjust the configuration of the in-vehicle components of the in-vehicle components using the user interface.
US09744850B2 Electric drive axle arrangement for a road vehicle
An electric drive axle arrangement for a road vehicle comprises an electric drive motor (1), a differential mechanism (3, 4) for allowing different velocities of drive wheels driven by the drive motor, and a torque vectoring system (2, 6, 7) for controlling the distribution of drive torque between the two drive wheels. A torque vectoring motor (2) of the torque vectoring system is of the non-permanent magnet motor type.
US09744845B2 Systems, methods, and devices for assessment of an operator of an electrically motorized vehicle
A system, method, and device for operations of an electrically motorized vehicle. The electrically motorized vehicle can utilize an electrically motorized wheel to convert a non-motorized wheeled vehicle to an electrically motorized wheeled vehicle. A user of the device for the electrically motorized wheel can be profiled by receiving data from a sensor system of the device and creating a profile of the user operating the vehicle from the data.
US09744843B2 Vehicle with electric transaxle
A vehicle comprises a transaxle, a battery and a load carrying bed. The transaxle includes a casing incorporating a drive train and supporting an axle and includes an electric motor mounted on the casing to drive the axle via the drive train. The battery is provided for supplying electric power to the electric motor. The transaxle and the battery are disposed below the load carrying bed so as to overlap the load carrying bed when viewed in plan.
US09744842B2 Device and method for learning engine clutch contact point of hybrid vehicle
A method for learning a contact point of an engine clutch configured to control connection of power between an engine and a motor of a hybrid vehicle is provided. The method includes performing a first learning of the contact point of the engine clutch by increasing a contact speed of the engine clutch and storing information of a first contact point learned by the first learning. A second learning of the contact point of the engine clutch is then performed by decreasing the contact speed of the engine clutch.
US09744841B2 Hybrid-power driving system for a vehicle and a transmission thereof
A hybrid-power driving system (HPDS) (100, 200) includes an engine, a motor, and a transmission. The HPDS may include a single clutch and the transmission can provide at least five forward speed ratios and can provide for at least one reverse speed ratio. The transmission can include three synchronizers and multiple gearwheels that are used in multiple speed ratios. In addition to a pure engine driving mode and a pure motor driving mode, the HPDS can operate using a hybrid-power driving mode (HDM). In the HDM, the HPDS can provide for shifting of gears without power interruption to the output shaft or half-axles and wheels of a vehicle. In the HDM, the continuous power being output can be achieved by keeping a synchronizer engaged with a gearwheel for two consecutive speed ratios.
US09744833B2 Sunroof apparatus
A sunroof apparatus includes: a movable panel adapted to open and close an opening formed in a roof of a vehicle; a guide rail provided in each edge portion of the opening in a width direction of the vehicle such that the guide rail is positioned below the movable panel in a height direction of the vehicle; an attachment member fixed to the movable panel, including a flange extending toward an interior side in the width direction in each edge portion in the width direction, in which an attachment recessed portion is formed in the flange; and a shielding body including interposing pieces which are provided to extend in a forward and rearward direction of the vehicle, slidably engaged with the guide rail, and extending in the width direction of the vehicle while being spaced away from each other in the height direction of the vehicle.
US09744831B2 Compressor comprising a pressure-relief groove
A compressor is disclosed. In one aspect, the compressor includes a pressure chamber which is delimited by at least two housing parts, the housing parts including sealing surfaces that are connected by a connection device which applies a contact pressing force between the sealing surfaces. At least one groove extending in a circumferential direction is arranged on at least one sealing surface. At least one relief opening is arranged on at least one of the housing parts. The relief opening connects the groove to the surroundings of the compressor and emanates from the groove. The groove is arranged such that when a predetermined maximum pressure is exceeded in the pressure chamber, a pressure-building medium can gather in the groove and at least partially escape through the relief opening.
US09744830B2 Heating panel for vehicle using far-infrared radiation
A heating panel for a vehicle includes a plate-shaped heating layer and a heat insulation layer attached to the heating layer. The heating panel is spaced apart from an occupant in an interior space of the vehicle and positioned to face the occupant. The heat insulation layer is directed toward the panel in the interior space and the heating layer is directed toward the occupant.
US09744824B2 Damping air spring and shock absorber combination for heavy-duty vehicle axle/suspension systems
A damping air spring and shock absorber combination for heavy-duty vehicle axle/suspension systems includes a damping air spring and a shock absorber both operatively attached to the axle/suspension system. The damping air spring primarily provides damping to the axle/suspension system over a first range of frequencies. The shock absorber primarily provides damping to the axle/suspension system over a second range of frequencies. The first range of frequencies is from about 0.0 Hz to about 6.0 Hz and the second range of frequencies is from about 0.0 Hz to about 13.0 Hz.
US09744822B2 Trailer coupling
In order to solve the problem, in the case of a trailer coupling comprising a ball neck supporting a coupling ball, and also comprising a socket receptacle for a socket for the power supply of units acting on the coupling ball, the socket having a socket housing with a housing sleeve, which is provided with an insertion opening, and the insertion opening being closable by a cover that is mounted pivotably on the housing sleeve, of being able to mount the sockets as conveniently and easily as possible, it is proposed that the socket receptacle has a receiving channel, into which the housing sleeve extends starting from a first side of the socket receptacle, that the housing sleeve bears against the first side of the socket receptacle via a bearing surface, and that the housing sleeve is fixed to the socket receptacle by a retaining element, which is fitted starting from a second side of the socket receptacle and which is supported on the socket receptacle and is connected to the housing sleeve by a latched connection.
US09744821B2 Trailer coupling
In a trailer coupling comprising a cross member which is mountable on a rear region of a vehicle body, a pivot bearing unit arranged on the cross member, by means of which a ball neck carrying a coupling ball is pivotally mounted about a pivot axis between a working position and a rest position, and a contact unit arranged on the ball neck as well as a cable harness guided from the contact unit to a vehicle-mounted cross member and provided for connecting to a vehicle electrical supply system, it is provided that a transition portion of the cable harness which runs in a movable manner relative to the ball neck and relative to the pivot bearing unit from the ball neck to an attachment point connected fixedly to the cross member forms at least one loop which extends over an end face of the pivot bearing unit extending transversely to the pivot axis and which varies in size when transferring from the working position to the rest position or vice versa.
US09744812B2 Tire assembly having an improved bead and a mounting rim
Assembly comprising a tire and a mounting rim, the tire comprising two beads each comprising at least one annular reinforcing structure and a carcass reinforcement anchored in the two beads by a turn-up, each bead comprising a filler of a rubber composition extending radially a radial distance DBE from the radially innermost point of the annular reinforcing structure, DBE being less than or equal to 10% of the radial height H of the tire, at least one sidewall further comprising a stiffening reinforcement of metallic reinforcing elements oriented at an angle less than or equal to 10 degrees to the circumferential direction, and positioned such that the distance DAE between the radially innermost point of the annular reinforcing structure and the radially outer end of the stiffening reinforcement is greater than or equal to 20% and less than or equal to 40% of H and that the distance DAI between the radially inner point of the annular reinforcing structure and the radially inner end of the stiffening reinforcement is less than or equal to 20% of H.
US09744809B2 Enhanced sound generation for quiet vehicles
The presence of an electrically-powered quiet vehicle is accomplished by determining a state of mind or physical state of the driver, determining the presence and proximity of humans and other objects, how the vehicle is being operated and generating a noise correlative to the threat posed by the vehicle to humans and other objects.
US09744803B2 Communication object having visible images and obscured portions for illuminated viewing, and method of making
A novelty communication object, such as a sign or printed object (book, brochure, greeting card or the like), and method of making, wherein at least one page, surface or sheet of the object has not only directly visible images, but also a plurality of cut-outs or other portions at least partially transparent or optically reactive to light, which can become visible when a user shines an illumination source such as a flashlight at the page and projects an image of the transparent or optically reactive portions onto a neighboring wall or other surface, or backlights the transparent or optically reactive portions for direct viewing. The plurality of transparent or optically reactive areas are preferably selected so that the illuminated image has a different visual appearance than the directly visible image, thereby enhancing the overall narrative content of the communication object.
US09744799B2 Pneumatically erasable slate
An erasable slate system includes a translucent layer adjacent a colored bottom layer, wherein application of a force to the translucent layer causes temporary adhesion of the translucent layer to the colored bottom layer in an area wherein the force is applied. The erasable slate system further includes an extending channel in fluid connection with the translucent layer and the colored bottom layer. The extending channel extends around at least 25% of the length of a perimeter of the bottom colored layer. The erasable slate system further includes an air pump in fluid connection with the extending channel via which pressurized air can be introduced into the extending channel to cause the translucent layer to be separated from adhesion to the colored bottom layer, thereby erasing markings, and via which air can exit the extending channel of the erasable slate system.
US09744798B2 Fluorescent blackboard
A fluorescent blackboard comprises a housing, a circuit hoard fixed on the housing by screws, a display screen fixed by the circuit board, and a panel attached and fixed on the housing by the adhesive tape. The fluorescence blackboard is configured with a fixed device that limits and fixes the panel. The present disclosure uses that the fluorescent blackboard 1 configured with the fixed device that limits and fixes the panel, which makes the panel be firmly limited and fixed on the housing, which avoids the panel from coming lose. When the panel is squeezed, the fixed device can protect the panel, which avoids damage to the panel.
US09744794B2 File folder
A file folder includes a rotatable cover and a closure mechanism. The closure mechanism secures the rotatable cover against a front of the file folder to maintain the file folder in a closed position. The closure mechanism further secures the rotatable cover against a back of the file folder to maintain the file folder in an opened position. The closed position protects contents of the file folder, while the opened position allows access to the contents of the file folder.
US09744793B2 Optical safety component having a transmissive effect, manufacture of such a component, and secure document provided with such a component
According to one aspect, the invention relates to an optical safety component having a plasmonic effect intended to be observed by transmission, including two layers (101, 103) made of a transparent dielectric material, a metal layer (102) that is arranged between said layers made of dielectric material to form two dielectric-metal interfaces (105, 106), and is structured to form on at least a portion thereof corrugations (104) that are capable of coupling surface plasmon modes supported by said dielectric-metal interfaces with an incident light wave. The corrugations are arranged in a first coupling area in a first main direction and in at least one second coupling area separate from said first coupling area, in a second main direction that is substantially perpendicular to said first main direction, said metal layer being continuous on each one of said coupling areas.
US09744792B2 Apparatus that is convertible between a social expression and a decorative item
An apparatus that is convertible between a social expression, such as a wedding invitation, and a decorative item, such as a votive candle holder. As a social expression, the apparatus is a flat, metal sheet which includes information pertaining to a social event that can be placed in an envelope and mailed to a recipient. Once the recipient receives the social expressions piece and the information regarding the social event is conveyed, the recipient can convert the social expression into a decorative item by folding along one or more folding lines. By converting the social expression into a decorative item, the apparatus has a greatly extended life.
US09744788B2 Stamp-face platemaking device, medium holder, and medium holder manufacturing method
A stamp-face platemaking device transports a medium holder inserted into a plate insertion portion to a printing unit. The medium holder holds a stamp face material at a center portion of a plate-like member, and has a cutout portion in one side end portion thereof. An optical sensor detects the top end portion of the medium holder on a sensor scanning line in the inserting direction, and the cutout start point and the cutout end point of the cutout portion. The size of the stamp face material in the inserting direction and/or the size of the stamp face material in a direction perpendicular to the inserting direction are set based on the positions of two of the detected end portions. When the cutout end point is detected, platemaking with the stamp face material is started. The cutout portion can have a wedge-like shape or a U-shape, or can change its positions and/or sizes.
US09744787B2 Tape cartridge and tape printing device
A tape cartridge or the like which can be pulled out of a cartridge loading section while maintaining a loading posture is to be provided. A tape cartridge is configured to be able to be loaded in and unloaded from a tape printing device. The tape cartridge includes a tab portion which is gripped at least at the time of unloading. The tab portion is arranged at or near a position where pull-out resistance due to unloading is balanced within a plane intersecting with an unloading direction.
US09744786B2 Liquid discharging apparatus
A liquid discharging apparatus is provided with a liquid discharging section that discharges a liquid onto a medium, and a transport section that transports the medium, and a piezoelectric film sensor is provided in the liquid discharging section. Due to a liquid discharging apparatus having such a configuration, it is possible to suppress a circumstance in which at least one of the medium and the liquid discharging section become damaged due to contact between the medium and the liquid discharging section.
US09744783B2 Liquid ejecting apparatus, liquid ejecting method, and non-transitory recording medium
A liquid ejecting apparatus for ejecting materials on a recording medium in accordance with a position of the apparatus and an image to be formed. The apparatus, movable on the recording medium by an external force, includes a position calculating unit configured to calculate the position; an electric power supplying unit configured to supply electric power to a part that the position calculating unit uses to calculate the position when a state of the apparatus changes to a second operating mode whose electric power consumption is less than that of a first operating mode of ejecting the materials; and a return factor detecting unit configured to detect a return factor for returning to the first operating mode from the second operating mode. When returning to the first operating mode, the apparatus restarts to eject the materials from the position that has been calculated in the second operating mode.
US09744781B2 Printer, and method and computer-readable medium for the same
A printer includes a controller configured to execute a printing process including sequentially printing a plurality of page images on a print medium based on print data while conveying the print medium in a conveyance direction, execute a first interruption process including, when a next cut distance is equal to or less than a printable distance, interrupting the printing process and stopping the print medium such that the next cut position coincides with a cutter position, and cutting the print medium, and execute a second interruption process including, when the next cut distance is more than the printable distance, interrupting the printing process and stopping the print medium such that the next cut position coincides with a position that is located an offset upstream of the cutter position in the conveyance direction.
US09744779B2 Active-light-ray-curable inkjet white ink and image forming method
Through the active-light-ray-curable inkjet white ink according to the present invention, the ink including a pigment, a dispersing agent, a wax, a photopolymerizable compound, and a photopolymerization initiator, and being capable of a sol-gel phase transition by a temperature change, the pigment including titanium dioxide surface-coated with alumina, the content of the titanium dioxide being 10% by mass to 15% by mass of the total mass of the ink, the ink including sodium ions in a mass ratio of 200 ppm or lower with respect to the pigment, and the dispersing agent including a comb-shaped block copolymer having a tertiary amine group, even when titanium dioxide is used as the pigment, the viscosity of the ink can be restrained from increasing, luster equivalent to that of another color is obtained, and clogging of a recording head for ink discharge is reduced.
US09744776B2 Device for printing on multi-dimensional objects
A device for printing on multi-dimensional objects includes an object carrier for holding and moving the object to be printed on, a tool carrier for receiving stationary processing tools, and a frame to which the tool carrier is fixed. The object carrier has three guide tracks which are disposed perpendicular to one another and each of which is oriented along a respective axis of movement. Carriages are movable on the guide tracks for executing a translatory movement of the object relative to the stationary processing tools. The device may have a modular construction, allowing the device to be adapted to a variety of objects to be printed on.
US09744773B2 Detecting ink characteristics
A method for determining characteristics of an ink is described. The method includes subjecting the ink of an inkjet printing system to an alternating signal of a first frequency to generate response signals from the ink, where the response signals include at least a response voltage signal and a response current signal. The method further includes comparing the response voltage signal to a predetermined voltage threshold, to generate a voltage phase signal, and comparing the response current signal to a predetermined current threshold, to generate a current phase signal. The method also includes tuning at least one of the predetermined voltage threshold and the predetermined current threshold to determine a balance point, and identifying a first relative phase difference between the voltage phase signal and the current phase signal, where the first relative phase difference is indicative of characteristics of the ink corresponding to the first frequency.
US09744772B2 Liquid supply system and inkjet recording device including the same
A liquid supply system includes a liquid supply source, an injection head, a damper in communication with the injection head, a liquid supply path including an end in communication with the liquid supply source and another end in communication with the damper, a liquid supply device supplying the liquid from the liquid supply source toward the damper, a pressure control valve provided between the liquid supply source and the liquid supply device, and a controller controlling the liquid supply device to be actuated or to be stopped. The pressure control valve closes the liquid supply path while the liquid supply device stopped.
US09744768B2 Liquid ejecting apparatus with ink receiving tray and detector
A liquid ejecting apparatus includes a liquid path that connects a liquid storage portion for storing liquid and a liquid ejecting portion for ejecting liquid, a receiving tray that is provided on a gravity direction side of the liquid path and is capable of receiving the liquid, and a detector that has a detecting portion for detecting the liquid received on the receiving tray. In the liquid ejecting apparatus, the receiving tray includes a receiving region for receiving the liquid, a detection region in which the detecting portion is arranged so as to make contact with the liquid, and a groove portion formed in the receiving region, and a part of the groove portion makes contact with the detection region.
US09744761B2 Liquid discharge device and head unit
A liquid discharge device includes a modulation circuit that generates a modulation signal obtained by pulse-modulating a source signal by self oscillation, a transistor pair which includes a high side transistor and a low side transistor and which generates an amplified modulation signal by amplifying the modulation signal, a demodulator which includes an inductor and a capacitor and which generates a drive signal by smoothing the amplified modulation signal, an piezoelectric element that is displaced when the drive signal is applied, a cavity inside which a liquid droplet is filled and whose internal volume is changed by the displacement of the piezoelectric element, and a nozzle provided to discharge liquid inside the cavity according to the change of the internal volume of the cavity. A distance between the high side transistor and the capacitor is longer than a distance between the inductor and the capacitor.
US09744760B2 Liquid ejection head, recording apparatus and heat radiation method for liquid ejection head
Provided is a liquid ejection head including: a plurality of recording element substrates including energy generating elements that generate ejection energy for ejecting liquid from ejection orifices; a first support member that supports the plurality of recording element substrates such that the recording element substrates are arranged in one or more lines on a main surface of the first support member; and a second support member that supports the first support member on a surface opposite to the main surface. A first thermal resistance concerning an in-plane direction parallel to the main surface, of a region between the recording element substrates in the first support member is higher than a second thermal resistance concerning a thickness direction of the second support member, of a projection region that overlaps with each recording element substrate in the second support member.
US09744753B2 Composite wood flooring and method of making the same
A method of making a composite panel configured for use with a flooring assembly of a trailer includes providing a wood substrate, making an uncured fiber-reinforced coating, and applying the uncured fiber-reinforced coating onto a surface of the wood substrate. The method further includes curing the uncured fiber-reinforced coating after applying the uncured fiber-reinforced coating onto the surface of the wood substrate.
US09744752B2 Inflatable panel and method of manufacturing same
A method of making an inflatable panel that includes the steps of: superimposing a second layer of a material of low gas permeability upon a first layer of a material of low gas permeability; creating a plurality of first elongated seals by intermittently sealing together the first and second layers, thereby defining a plurality of first tubes between adjacent pairs of the first elongated seals. The method also includes sealing rear ends of the first tubes; inflating the first tubes from front ends thereof with a gas; and then sealing the front ends of the first tubes, such that the gas within each of said tubes is prevented from flowing between the first tubes.
US09744748B2 Multilayered structure and laminate, and method for production of the same
An object of the invention is to provide a multilayered structure having very superior gas barrier properties and being excellent in flex resistance, pinhole resistance, stretchability, thermoformability and interlayer adhesiveness, and having superior durability enabling characteristics such as high gas barrier properties to be maintained even if used with deformation such as flexion and/or stretching, and to provide a laminate in which the multilayered structure is used, and a production method thereof. Provided by the present invention is a multilayered structure in which at least 4 resin-layers constituted with a resin composition containing an ethylene-vinyl alcohol copolymer are contiguously laminated. A single layer of the resin layer has an average thickness of preferably no less than 0.01 μm and no greater than 10 μm. The average thickness is preferably no less than 0.1 μm and no greater than 1,000 μm. When the content of ethylene units of the ethylene-vinyl alcohol copolymer is no less than 3 mol % and no greater than 70 mol %, the saponification degree is preferably no less than 80 mol %.
US09744745B2 Circuit substrate and manufacturing method thereof
Provided is a circuit substrate, including a glass film (10) forming a rough layer (11) after surface roughness processing, a resin adhesion (20) located the rough layer (11) on either side of the glass film (10), and a metal foil (30) located on the outside of resin adhesion layer (20). The glass film (10), the resin adhesion layer (20) and the metal foil (30) are joined together through suppressing. The circuit substrate employs the glass film (10) which forms a rough layer (11) after surface roughness processing as a carrier material, so that the resin adhesion layer (20) and the surface of the glass film (10) have a good binding force, and the dielectric constant of the circuit substrate has slight difference in the directions of X, Y and Z. Also provided is manufacturing method for a circuit substrate.
US09744738B2 Embossed sheet and method of making and using same
A embossed sheet embossed with projections creating an intermittent support surface for food. The embossed sheet may be inserted into a food package after cooking the food on which the cooked food is to be supported. Alternatively, the embossed sheet may be placed onto or into a pan or directly onto an oven rack to support the food while cooking and/or after cooking. Alternatively, the embossed sheet may be formed into a food package. The embossed sheet may be prepared using a one-pass or two pass process using a platen press or a roll-to-roll press or a multi-stage one pass machine.
US09744735B2 Method for forming golf ball and mold therefor
A method for forming a golf ball provides a core member comprising a core of a golf ball into a cavity of a mold so that the core member is supported by a movable holding pin disposed in the mold; forming a layer outside the core member by injecting a material of the layer into the cavity; and retracting the pin from the cavity into the mold during the material injection so that a portion projecting from a surface of the layer is formed by a tip of the pin, the projecting portion having a site area of at least 0.2% in relation to an entire area of the tip of the pin and having a height of at least 0.2 mm. This method can be implemented by controlling the retraction of the pin, or alternatively by using the pin having a predetermined indentation portion on the tip.
US09744731B2 Installations for manufacturing biaxially oriented tubing and the tubing itself
The production of a biaxially oriented tube from thermoplastic material, wherein a tube in preform condition is extruded from thermoplastic material using an extruder having an extruder die head with an inner die member that forms a lumen in the tube in preform condition. The tube in preform condition is subjected to a temperature conditioning. Use is made of a expansion device comprising a non-deformable expansion part having a gradually increasing diameter to a maximum diameter, which expansion part is contacted by the tube and exerts an expanding force so as to bring about expansion of the tempered tube in circumferential direction. The method comprises drawing the tempered tube over the expansion device using a drawing device, in such a manner that said tube is transformed from a tube in preform condition into a biaxially oriented tube with thermoplastic material which is oriented in axial direction and in circumferential direction of the tube.
US09744724B2 Apparatus for printing a chemical mechanical polishing pad
A method of fabricating a polishing layer of a polishing pad includes successively depositing a plurality of layers with a 3D printer, each layer of the plurality of polishing layers deposited by ejecting a pad material precursor from a nozzle and solidifying the pad material precursor to form a solidified pad material.
US09744721B2 Kitchen appliance especially a food printer
The invention relates to a kitchen appliance, especially a food printer, and a method for printing food in 2- or 3-dimensional shapes. The food printer for making 2- or 3-dimensional shapes comprising a housing, an opening for printable food and binder, a control unit, and a printer head, wherein the printer head prints small drops of the printable food and the binder while moving to build the 2- or 3-dimensional shape.
US09744715B2 Method for producing patterned materials
A large area patterned film includes a first patterned area; a second patterned area; and a seam joining the first patterned area and the second patterned area, wherein the seam has a width less than about 20 micrometers. A method for tiling patterned areas includes depositing a predetermined thickness of a curable material; contacting a first portion of the curable material with a mold; curing the first portion of the curable material; removing the mold from the cured first portion of the curable material; contacting a second portion of the curable material with the mold, such that the mold contacts a portion of the cured first portion of the curable material; curing the second portion of the curable material; and removing the mold to yield a seam between the cured first portion of the curable material and the cured second portion of the curable material, wherein the seam has a dimension less than about 20 micrometers.
US09744711B2 Method and apparatus for blowing and filling containers with release of liquid overpressure
The invention concerns an apparatus for blowing and filling a container (22) from a preform (16), said apparatus comprising: —a mold (12) for enclosing a preform (16), —stretching means for stretching the preform (16) placed within said mold (12), —a pressurized liquid injection circuit (18) able to inject a liquid under pressure inside said preform (16) when said preform is placed inside said mold, —injection means which are adapted to inject a predetermined volume of liquid through said liquid injection circuit (18) into the preform and to stop injection of the liquid through said circuit into the preform when a blown and filled container (22) has been obtained, stopping the injection of the liquid through the liquid injection circuit into the preform creating an overpressure of the liquid within the liquid injection circuit, characterized in that the apparatus further comprises releasing means for releasing said overpressure of the liquid within the liquid injection circuit.
US09744708B2 Slot die position adjustment and return to baseline
A method of controlling a slot die comprises, while continuing to pass the extrudate through the fluid flow path and out the applicator slot, changing the position of the actuators with the controller to either increase the cross-directional thickness of the fluid flow path adjacent each of the actuators or substantially close the fluid flow path adjacent the actuators, and after changing the cross-directional thickness of the fluid flow path adjacent each of the actuators, while continuing to pass the extrudate through the fluid flow path and out the applicator slot, repositioning each of the actuators with the controller according to the set of discrete settings to resume operating the slot die with the actuators positioned according to the set of discrete settings.
US09744707B2 Extrusion-coated structural members having extruded profile members
The present disclosure relates to extrusion-coated structural systems including at least one extruded profile member coupled to and extending outwardly from an extrusion-coated structural member, as well as methods of making and using the same. Structural systems of the present invention that include at least one extruded profile member may exhibit enhanced flexibility, functionality, and/or durability. Structural systems according to embodiments of the present invention can be suitable for use in a variety of applications, including in ready-to-assemble furniture or cabinetry applications or as building and construction materials such as wall board, flooring, trim, and the like.
US09744692B2 Three-dimensional shaping device and three-dimensional shaping method
Control means performs control such that a head section 20 is caused to perform reciprocating scanning in one direction, a model material MA and a supporting material SA are ejected onto a shaping plate 40, and the model material MA and/or the supporting material SA are cured in at least any one of forward and backward paths of the reciprocating scanning, to form slices, and relative positions of the shaping plate 40 and the head section 20 are moved in a height direction to repeat lamination of the slices, thereby performing shaping, and on a line where the model material MA and the supporting material SA are located in a scanning direction of a shaped object, the model material MA and the supporting material SA are not simultaneously ejected during the same reciprocating scanning, but only one shaping material can be ejected and cured.
US09744690B2 Metered pump system for hydrocapsule encapsulation
A metered pump system for hydrocapsule encapsulation is disclosed. In at least one embodiment, a system for hydrocapsule encapsulation includes a nozzle assembly and metered pump for encapsulating discrete droplets of liquid by generating a continuous coating of a polymerizable liquid which is substantially immiscible with the core liquid. The metered pump system is configured to control a stroke length and a pulsation speed to attain constant shear with each pump of water, and a volume of water in each stroke and a speed of the stroke is controlled. In at least one embodiment, the nozzle includes a material feed port, a polymer feed port, a water feed port, and an encapsulated material exit port. In at least one embodiment, the metered pump is configured for use in a hydrocapsule encapsulation system having a pressure control system, a water control system, sparging column, and ultraviolet exposure chamber system.
US09744689B2 Apparatus for the pretreatment and subsequent conveying, plastification, or agglomeration of plastics
The invention relates to an apparatus for the pretreatment and subsequent conveying or plastification of plastics, with a container with a mixing and/or comminution implement that is rotatable around an axis of rotation, wherein, in a side wall, an aperture is formed, through which the plastics material can be removed, a multiscrew conveyor being provided, with at least two screws rotating in a housing, wherein the imaginary continuation of the longitudinal axis of the conveyor in a direction opposite to the direction of conveying passes the axis of rotation, where, on the outflow side, there is an offset distance between the longitudinal axis of the screw closest to the container and the radius that is parallel to the longitudinal axis, and in that the two screws closest to the intake aperture are counter-rotating relative to one another.
US09744682B2 Heated utility knife
A heated utility knife is disclosed for heating a material to be cut in order to soften the material before cutting the material. The heated utility knife is made of a knife portion that has a blade with a distal cutting edge, and a heat source configured to direct heat to a region adjacent the cutting edge. The heat source has a head portion which sits below the cutting blade. Pulling the cutting edge across a material to be cut allows heat from said heat source to be directed to the material to be cut to soften the material prior to cutting.
US09744678B2 Methods and systems to provide feedback based on a motion per path metric indicative of an effect of motion associated with components of a robotic device
Examples are provided that describe a motion based light display for a robotic arm. In one example, a robotic device comprising one or more components configured to be actuated for movement. The robotic device also includes one or more processors are configured to determine a motion per path metric of the one or more components based on a motion plan associated with the robotic device. The one or more processors are configured to determine one or more feedback characteristics based on the motion per path metric. The one or more feedback characteristics include information indicative of an effect of motion associated with the one or more components. The robotic device also includes an indicator coupled to the one or more components and configured to provide feedback about the one or more components based on the feedback characteristics indicative of the effect of motion.
US09744675B1 Gripper capable of lifting a work piece
A gripper capable of lifting a work piece includes: a body including a sliding direction and a lifting axis defining a first angle relative to the sliding direction; a plurality of sliding blocks slidably mounted on the body and located at two sides of the lifting axis to move in the sliding direction toward or away from each other, wherein the sliding blocks each include a receiving hole at a second angle relative to the sliding direction; and a plurality of fingers slidably disposed in the receiving holes, and each including: a nose portion disposed in the receiving holes, and a finger portion to grip the work piece. When the sliding blocks are in the lifting position, the fingers are retracted into the receiving holes to make the finger portions move up along the lifting axis toward the body by a certain distance while clamping the work piece.
US09744674B2 Gripper and process for manufacturing a gripper
A gripper is described as including two lateral flanks that are directly or indirectly connected to each other at one end, providing a space between them including an actuator, the lateral boundaries of which space have at least one opening accessible from the outside. At least one louver runs across the opening and divides the opening such that the partial surfaces resulting from the louver limit or prevent accessibility to the opening. A method for manufacturing the gripper is also described.
US09744667B1 System and method for promoting safety of a robotic appendage
A system for promoting safety of a robotic appendage includes: a robot controller; and a robot controllable by the robot controller, the robot controller configured to compute an estimated power draw of a planned trajectory of the robot, the robot controller further configured to modify the planned trajectory to prevent the estimated power draw from exceeding a power limit; the robot comprising: an appendage; an appendage controller configured to control the appendage; and a breaker configured to limit power delivered to the appendage. A system for promoting safety of a robotic appendage includes a plurality of robots operably connected with each other, the robots configured to communicate with each other regarding estimated power draw characteristics.
US09744664B1 Edge protector clip kit
The edge protector clip kit is a device that is adapted to work with an edge protector that is placed on a top, edge of a load of cargo. The edge protector clip kit includes a telescoping pole that is manually grasped in order for a user to manipulate the edge protector. The edge protector clip kit includes a clip holder that is adapted to engage the edge protector from below, and which enables manipulation of the edge protector via the telescoping pole. The telescoping pole is affixed to the clip holder. The clip holder includes a pair of armatures that are adapted to engage opposing sides of a vertical portion of the edge protector. The clip holder also includes a light and on/off button.
US09744662B1 Double-pin locking extensible handle
A telescoping handle includes an outer tubular rod, an inner rod and a lock. The lock is made of a collar; two arc-rings, two retaining covers, and two buttons. The collar slides over the outer tubular rod and the inner rod slides into the other end. A recess in the collar holds two arc-rings that define an inwardly projecting pin sized to pass through the collar and into a hole on the inner rod. Two buttons passing through covers to the recesses enables contact with the two arc-rings causing each projecting pin to withdraw from the inner rod when pushed. When released, each button disengages from the two-arc rings causing the projecting pin to slide into a hole in the inner rod to prevent movement of the inner rod. A spring may be used to bias the two arc-rings into engagement with the inner rod.
US09744658B2 Power tool operation recording and playback
A power tool and method for recording and playing back a motor parameter. The power tool includes housing, a motor, a trigger, a mode selector switch, and a controller. The trigger outputs an activation signal based on a user input. The mode selector switch is configured to receive a user mode selection indicating a recording mode, a normal operating mode, or a playback mode. The controller receives a mode selection signal from the mode selector switch indicating the selected mode. The controller enters the recording mode when the user mode selection indicates the recording mode, and records a motor parameter while the power tool is in the recording mode to generate a recorded motor parameter. In the playback mode, the controller operates the motor based on the recorded motor parameter upon receiving the activation signal from the trigger.
US09744656B2 Clamping device for expanding a threaded bolt
A clamping device for expanding a threaded bolt is provided with a support pipe supported against an underlay surrounding the threaded bolt. A cylindrical housing arranged in extension of the support pipe has a piston movable in longitudinal direction and connectable to a hydraulic supply. A changeable bushing is axially carried by the piston and is provided with an inner thread and a radially expanded portion. A resilient arrangement is arranged around the bushing and acts axially on the piston. A lid is secured to the housing. The other support of the resilient arrangement is provided on the lower side of the housing. The lid has a lid base member and a closure lid. The lid base member is provided with an opening closable by the closure lid. The radial extent of the opening is greater than the radial extent of the radially expanded portion of the bushing.
US09744648B2 Mounting with interconnected cavities for holding an abrasive, method for producing such a mounting, grinding system and use of such a mounting
A mounting element for holding a self-adhesive and/or flexible abrasive includes a supporting plate, and a distributing body. The supporting plate includes a plurality of suction openings which penetrate the supporting plate from a first side to a second side opposite the first side. A first side of the distributing body is in contact with the second side of the supporting plate, and a second side of the distributing body is configured to hold an abrasive. The distributing body includes a plurality of cavities which penetrate the distributing body from the first side of the distributing body to the second side of the distributing body, and which are mutually separated by a plurality of walls. At least one of the walls has at least one aperture which connects at least two adjacent cavities to each other.
US09744644B2 Cladding having an architectural surface appearance
A panel including a surface made of a synthetic material may be subjected to a material removal process to create a specific decorative or architectural appearance. In one embodiment, a panel of cellular PVC is blasted with an abrasive material such as crushed glass to create a realistic stucco appearance on the panel surface. Benefits related to using certain synthetic materials as cladding may be realized, such as weather resistance. A coating containing aggregate may be applied to the blasted panel to enhance the surface appearance.
US09744640B2 Corrosion resistant retaining rings
Implementations described herein protect a retaining ring for a polishing system from corrosive polishing chemistries. In one embodiment, a retaining ring has a ring-shaped body having a top surface, an inside diameter sidewall, an outer diameter sidewall and a bottom surface. The inside diameter side wall is configured to circumscribe a substrate. The ring shaped body has a rigid ring-shaped portion, a polymeric ring-shaped portion stacked on the rigid ring-shaped portion and covering at least three sides of the rigid ring-shaped portion, a plurality of grooves formed in the bottom surface, and a plurality of wash ports formed through the polymeric ring-shaped portion, wherein the wash ports are isolated from the rigid ring-shaped portion.
US09744639B2 Pressing device for pressing a finishing belt against a workpiece surface
The invention relates to a pressing device for pressing a finishing belt against a workpiece surface, including a pressure belt and a pressure belt carrier which supports the pressure belt at two mutually spaced-apart support points, wherein the pressure belt is fastened releasably to the pressure belt carrier, wherein, in order to fix in each case one pressure belt end, provision is made of a fixing device that is provided separately from the pressure belt carrier, and wherein the fixing device is fastened or fastenable releasably to the pressure belt carrier in a state in which one pressure belt end is fixed to the fixing device.
US09744638B2 Method for decoating a glass panel
When decoating a glass panel (3), a decoating tool (6) with a circular-cylindrical grinding element (8) is used, which element is set to rotate around its axis. In the end face of the grinding element (8) that is used when the active face (9) is decoated, a hole (10) and at least one radial groove (11) are provided. The decoating tool (6) is placed at a spot (A) on the glass panel (3) in a movement (arrow 13) that is oriented at an acute angle to the plane of the glass panel (3), which lies between the ends (B) and (C) of the strip-shaped decoating area (14) and moves first to the one end (B) (arrow 15) and then to the other end (C) (arrow 16) in order to strip coating from the glass panel (3) in the decoating area (14).
US09744637B1 Floor processing system
A floor processing system for a skid steer loader includes a shroud having an attachment device configured to removably engage with the skid steer loader; a central motor secured to the shroud and rotatably attached to an arm; a first rotary assembly secured to the arm; and a second rotary assembly secured to the arm. The first rotary assembly includes a first disc rotatably attached to a first motor via a first shaft; and a plurality of first cutters extending from the first disc. The second rotary assembly secured to the arm includes a second disc rotatably attached to a second motor via a second shaft; and a plurality of second cutters extending from the second disc.
US09744635B2 Machine for replacing disc tools
A method and a machine for automatically changing a disc tool to a tool holder of an automated machine working with the disc tools is disclosed. The method includes in the disc tool replacement machine: determining that the tool holder is in a replacement area in the disc tool replacement machine; unfastening a fixing member of the tool holder by applying an unfastening force to the fixing member, wherein the fixing member fixes a disc tool to a backing plate of the tool holder through a through hole at a centre of the disc tool; removing the disc tool from the tool holder after said unfastening; inserting a new disc tool to the tool holder; and fastening the fixing member of the tool holder by applying a fastening force to the fixing member, thus fixing the disc tool to the backing plate of the tool holder through the through hole.
US09744634B2 Support for workpieces
The application is related to adjustable supports for holding objects in one or more desired fixed orientations, including but not necessarily limited to objects that lack uniformity as to size and/or shape and/or weight.
US09744630B2 Method of conforming an overwrap to a pessary device
This application relates to a method of covering a pessary device for relief of female incontinence with an overwrap. More particularly, the present invention relates to methods of conforming the overwrap to the pessary device.
US09744625B2 Laser system and processing conditions for manufacturing bioabsorbable stents
The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof.
US09744622B2 Moving a laser processing head relative to a clamping claw
A laser processing device for processing workpieces such as by welding includes a laser processing head and a workpiece clamping claw defining an opening through which the laser beam is focused on the workpiece. Each of the laser processing head and the clamping claw have respective shielding portions and movable relative to each other to selectively form a light-tight housing about a portion of the beam extending between the laser head and the clamping claw.
US09744617B2 Methods for perforating multi-layer graphene through ion bombardment
Multi-layer sheets of graphene-based material having a plurality of pores extending therethrough are described herein. Methods for making the sheets include exposing a graphene-based material comprising multilayer graphene having from 5 to 20 layers of graphene to a particle beam having an ion energy of at least about 1500 eV to create damage tracks in the graphene sheets. The damage tracks in the graphene sheets are then exposed to a chemical etchant, such as an oxidant to define pores through the stacked graphene sheets. Production of the damage tracks and etching of the damage tracks can take place while the graphene is disposed on a substrate.
US09744613B2 Flux recovery device and soldering device
A flux recovery device that recovers a flux component from a gaseous mixture. The flux recovery device includes a first water spray unit that sprays water into a gaseous mixture containing the flux component, a separation unit that includes an introduction port for introducing the gaseous mixture into which water is sprayed from the first water spray unit, and a second water spray unit that forms a precipitation flow inside of the separation unit. The separation unit uses a swirling flow to separate the flux component from the gaseous mixture. A condensation unit cools water vapor generated in the separation unit to change the water vapor to water droplets, thereby removing the water vapor. Water vapor generated in a separation unit is cooled by a condensation unit, recovered as water droplets, and reused.
US09744608B2 Wire electric discharge machine
A primary power supply charges a capacitor by turning on a switching element and, upon completion of charging, turns off the switching element. Then, an AC pulse voltage is applied to the gap between a wire electrode and a workpiece by alternately turning on and off a switching element present in a secondary power supply. After a dielectric breakdown occurs between the wire electrode and the workpiece, the switching element is turned on to connect the capacitor so that the capacitor supplies a pulse current for machining.
US09744602B2 Work piece chuck of a manipulator
The present invention provides a work piece chuck of manipulator in the field of mechanical technology. The chuck comprises a chuck sleeve and an ejector pin set within the chuck sleeve. An elastic clamping element is provided at the front end of the chuck sleeve. The ejector pin could move between a first position and a second position along the axial direction of the chuck sleeve. When the ejector pin is in the first position, the outer circumference of the ejector pin extrudes the clamping element to distort and expand outward to form an expansion state. When the ejector pin is in the second position, the outer circumference of the ejector pin is out of contact with the clamping element to restore the clamping element. The chuck has a number of advantages including firm connection, high reliability and high use value.
US09744596B2 Machine tool
The invention provides a machine tool eliminating the need of keeping the removed feed-mechanism-protection cover outside the machine. The machine tool comprises a headstock provided with a main spindle for gripping a workpiece; a driving unit provided with a feed mechanism extended along a main spindle axis to move the headstock in a main spindle axial direction; a supporting bed provided with a guide bush in a removable manner; a first cover mounted on the headstock to protect a portion of the feed mechanism with respect to the main spindle axial direction; and a second cover removably mounted on the headstock on the front side of the first cover to protect another portion of the feed mechanism. The second cover is detachably attached to the first cover when removed from the headstock.
US09744595B2 Coated copper particles and method for producing the same
A method for producing coated copper particles having a surface coated with an aliphatic carboxylic acid, wherein the method comprises obtaining a reaction mixture containing copper formate, an amino alcohol, an aliphatic carboxylic acid having an aliphatic group having 5 or more carbon atoms, and a solvent, and subjecting a complex compound formed in the reaction mixture to thermal decomposition treatment to form metal copper, wherein a ΔSP value, which is a difference in SP value between the amino alcohol and the solvent, is 4.2 or more.
US09744592B1 Fabricating multi-part assemblies
Techniques are disclosed for fabricating multi-part assemblies. In particular, by forming release layers between features such as bearings or gear teeth, complex mechanical assemblies can be fabricated in a single additive manufacturing process.
US09744589B2 Method and apparatus for controlling variable shell thickness in cast strip
Apparatus and method for continuously casting metal strip includes a pair of casting rolls having casting surfaces with a center portion, edge portions each having average surface roughness between 3 and 7 micrometers Ra, and intermediate portion between each edge portion and the center portion, the center portion average surface roughness between 1.2 and 4.0 times the edge portion surface roughness, and the intermediate portions average surface roughness between that of the edge and center portions. The surface roughness of the center portion is tapered across its width, and may be tapered across its width is in stepped zones. The center portion may have surface roughness varied across the surface to correspond to a desired variation in metal shell thickness across the cast strip. The center portion may be at least 60% of the casting roll width, and each edge portion may be up to 7% of the casting roll width.
US09744581B2 Hole punching pliers and method of using same
Disclosed are pliers and related methods for punching a hole in a non-flat material without distorting the material. Such pliers may comprise a first member having a first handle and a first jaw, and a second member having a second handle and a second jaw. The first and second members are attached at a connection point to permit pivoting in response to a squeezing force on the handles. The first jaw comprises a punch tip to be received by the second jaw, where the punch tip may have an angled distal end truncating a cross-section of the punch tip. The second jaw comprises a shaped edge facing the punch tip and extending along a length of the second jaw, the shaped edge having substantially the same shape as the non-flat material and comprising an opening having substantially the same shape as the cross-section of the punch tip and to receive the tip therein.
US09744580B2 Ironing mold and formed material manufacturing method
An ironing mold according to the present invention is provided with a punch, and a die which forms a pushing hole with respect to the punch. When the skewness Rsk of a surface treated metal plate is less than −0.6 and no less than −1.3, then the curvature radius of a shoulder portion of the die and a clearance between a radius end and the punch are determined such that Y, which is expressed by {(tre−cre)/tre}×100, and X, which is expressed by r/tre, satisfy 0
US09744578B2 Crystal growth crucible re-shaper
Roll forming is used for re-shaping an iridium crucible. The crucible is placed on a platen. The platen rotates the crucible while heat is applied by a plurality of torches. A plurality of rollers press on the rotating, heated crucible to re-shape. The roll forming allows for a greater number of repetitions of the re-shaping, increasing the number of uses per expensive re-fabrication of the crucible. The roll forming may provide more exact re-shaping.
US09744576B2 Lock ring
A lock ring that has a first ring half, a second ring half and a latch assembly. The first ring half includes a nest opening on a front portion of the first ring half, a back end portion of the first ring portion hingedly connected to a back end portion of the second ring half. The latch assembly is connected to a front portion of the second ring half. The latch assembly includes a connection arrangement and a spring system. The connection arrangement is designed to be releasably positionable in the nest opening. The spring system is designed to cause the front portions of the first and second ring halves to be drawn toward one another when the connection arrangement is positioned in the nest opening.
US09744575B2 Treatment of waste
A method for the treatment of waste by plasma treating the waste to destroy the hazardous organic components and to yield a slag and an off-gas by plasma treating the waste in the presence of added oxygen gas in a transferred-arc plasma treatment unit, followed by directing off-gas from the plasma treatment unit to a thermal oxidizer combustion chamber.
US09744573B2 Substrate case cleaning apparatus
Contaminant is prevented from migrating from a gripping hand and contaminating a substrate case after cleaning the substrate case. The apparatus cleans, in a state with no substrate, a substrate case C which holds a substrate, provided with a booth 10 which forms a clean space, provided with cleaning tanks 40, 50 which hold and clean the parts of the substrate case C in a separated status in the booth 10, provided with a conveyance mechanism 60 which grips part of the substrate case C by a gripping hand 70 and conveys them to and from the cleaning tanks 40, 50, making the gripping hand 70 stand by at a standby position Q in the booth 10 during cleaning of the substrate case C, and provided with a cleaning means 80 for cleaning the gripping hand 70 during cleaning of the parts. The cleaning means 80 is provided with a spray nozzle 81 which sprays a gas toward the gripping hand 70 and an exhaust fan 82 which exhausts the gas from the inside of the booth 10.
US09744572B2 Apparatus for removing solids from sewers
A sewer cleaning apparatus which has a hollow cylindrical body propelled by a plurality of water jets with a clam shell opening on the front of the apparatus operated by a plurality of piston assemblies that are attached to the sides of the cylindrical body. The apparatus is propelled by high pressure water ejected from the apparatus in a rearward direction. The high pressure water operates the piston assembly opening the clam shell and provides forward thrust for the apparatus allowing the hollow bucket type object to trap solids inside apparatus.
US09744571B1 Portable resonance induction cleaning system
A portable resonance induction cleaning system for cleaning a process tubular or heat exchanger can include a portable high pressure plunger pump, which can provide a liquid to the portable resonance induction cleaning apparatus. The portable resonance induction cleaning apparatus can regulate flow of the liquid to provide pressurized pulses of the liquid with a resonance for removing fouling. A hose assembly or ram connecting mechanism can provide the pressurized pulses of the liquid to the process tubular or heat exchanger. Air can be used to control flow of the pressurized pulses of the liquid. A hydraulic intensifier can be in fluid communication with the portable resonance induction cleaning apparatus for receiving the air, and a hydraulic control valve can be bi-directionally engaged with the hydraulic intensifier and the hydraulic ram. The hydraulic ram can seal with the heat exchanger to provide the pressurized pulses of the liquid thereto.
US09744564B2 Vibratory separator screen
A vibratory separator includes a screen frame having an upper screen surface and a plurality of openings and a first screen insert disposed in a first opening of the plurality of openings of the screen frame, the screen insert having a screen surface positioned at a first height above the supper screen surface. The vibratory separator also includes a second screen insert disposed in a second opening of the plurality of openings of the second screen frame, wherein a screen surface of the second screen insert is positioned at a second height. The second height may be different from the first height. A method of processing fluid includes providing a flow of fluid to a vibratory separator, and flowing the fluid over a screen having a first screen insert positioned at a first height.
US09744561B2 Barrier coating corrosion control methods and systems for interior walls of pipe in underground piping
Methods and systems for providing cleaning and providing barrier coatings to interior wall surfaces of small diameter metal and composite piping systems in buildings. An entire piping system can be cleaned in one single pass by dry particulates forced by air throughout the building piping system by an external generator, and the entire piping system can be coated in one single pass by a machine connected exterior to the piping system. Small pipes can be protected by the effects of water corrosion, erosion and electrolysis, extending the life of piping systems such as copper, steel, lead, brass, cast iron piping and composite materials. Coatings can be applied to pipes having diameters of approximately ⅜″ up to approximately 6″ so that entire piping systems such as potable water lines, natural gas lines, HVAC piping systems, drain lines, and fire sprinkler systems in single-family homes to apartments to high-rise hotel/resort facilities and office towers, apartment and condominium buildings and schools, can be cleaned and coated to pipes within existing walls. The coating forms an approximately 4 mils or greater covering inside of pipes. Buildings can return to service within approximately 24 to approximately 96 hours.
US09744549B2 System and method for dispensing material
A liquid dispensing method including steps of: providing a dispensing device having a refill time (RT) and repeatedly energizing the activation elements at a frequency greater than about 1/(RT). The device includes: a plurality of liquid dispensing elements, each element including: a chamber having a height (H), a nozzle having a diameter (D), an activation element having a length (L), and the refill time (RT); a liquid containing reservoir in fluid communication with the liquid dispensing elements; and a control element in electrical communication with the liquid dispensing elements. The ratio of the nozzle diameter (D) to chamber height (H) is between about 3 and about 10.
US09744548B2 Telescoping spray wand assembly
The invention provides a telescoping wand assembly for use in dispensing liquid from a container, including a trigger module extending along a longitudinal axis between proximal and distal ends. The trigger module includes a tubular handle member, a user accessible trigger positioned externally of the tubular handle member that is selectively movable between first and second positions, a hose positioned within the tubular handle member and adapted to transport liquid from the container, and a valve actuating member that is selectively, movably actuable by movement of the trigger between its first and second positions. A stationary frame assembly provides rigidity and contact points for a telescopically movable tube assembly that extends from the trigger module. A shut-off valve and nozzle are positioned at the distal end of the wand assembly and movement of the shut-off valve is controlled by the trigger and translated by way of the tube assembly.
US09744542B2 Agricultural skin grafting
A method of forming a material structure from structural units contained within a liquid solution in a spray head is described. The liquid solution includes a solvent and a solute, the solute comprising a plurality of the structural units, the structural units including monomer units, oligomer units, or combinations thereof. The method comprises forming droplets of the liquid solution including the structural units, and spraying the droplets on a substrate, thereby substantially increasing the reactivity of the structural units within the droplets relative to the structural units within the liquid solution in the spray head. The increase in reactivity can result from the droplets containing an excess of a particular ion, the ion excess resulting from a voltage applied to conductive walls of the device which dispenses the droplets. The material structure is then formed on the substrate from the more highly reactive structural units within the droplets.
US09744541B2 Water pulsating device for irrigation systems
A pulsating device has a chamber for receiving liquid entering the device and gas that occupies an initial volume in the chamber. The liquid entering the chamber compresses the gas and decreases the volume occupied by the gas, thereby increasing the pressure in the chamber. A valve is provided to open above a first threshold pressure to begin a pulse of liquid. The valve closes below a second threshold pressure to end the pulse. The pulsating device has an outlet gate that permits liquid in the chamber to exit the chamber when the pressure in the chamber is greater than the pressure outside the chamber.
US09744540B2 Water injector nozzle
A water injector assembly includes an injector body having a substantially hollow interior. The injector body defines an inlet opening defined within an outer radial surface of the injector body at a first axial location along the injector body. The injector body defines a flowpath opening in fluid communication with the inlet opening such that the flowpath opening is configured to receive the fluid from the inlet opening. The injector body defines an outlet opening defined within the injector body at a second axial location along the injector body. The outlet opening is in fluid communication with the flowpath opening, such that the outlet opening receives the fluid from the flowpath opening. The second axial location of the outlet opening is different than the first axial location of the inlet opening.
US09744539B2 Container cleaning device
A container cleaning device includes a mounting plate shaped for accommodating a wafer; and a nozzle assembly disposed on the mounting plate and including a base and a shell complimentarily disposed on the base. The shell includes an inlet and at least one outlet member disposed on an edge. The base includes a recess communicating with the inlet, and at least one outlet element each being inclined at a predetermined angle with respect to the shell. Each outlet member of the shell is adjacent to and communicates with the corresponding outlet element of the base.
US09744532B2 Multi-directional microfluidic devices comprising a pan-capture binding region and methods of using the same
Microfluidic devices and methods for using the same are provided. Aspects of the invention include microfluidic devices that include a separation medium and a pan-capture binding medium. The microfluidic devices are configured to subject a sample to two or more directionally distinct electric fields. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.
US09744527B2 Article having antifouling properties for aquatic and particularly sea use
An article having antifouling properties and intended to be employed in aquatic uses, in particular marine uses, which comprises: a) a support, b) optionally, at least one primer coat on said support comprising at least one anticorrosive product, c) optionally, at least one intermediate primer coat promoting adhesion between the coats, d) at least one adhesion-promoting coat or tie coat, deposited on said primer coat or on said support when the primer coat is absent, and e) at least one antifouling coat or topcoat, deposited on said adhesion-promoting coat or tie coat.
US09744523B2 Hydrogen production from water by tuning the photonic band gap with the electronic band gap of a photoactive material
Disclosed is a photocatalyst, and methods for its use, that includes a photoactive material comprising a photonic band gap and an electronic band gap, wherein the photonic band gap at least partially overlaps with the electronic band gap, and an electrically conductive material deposited on the photoactive material.
US09744519B2 Spherical agglomerates based on zeolite(s), process for the production thereof and use thereof in adsorption processes or in catalysis
The present invention relates to spherical agglomerates based on zeolite(s) and clay(s), having controlled size and morphology, in particular a size of less than or equal to 600 μm, very good sphericity, and a high content of zeolitic material, to the process for the production thereof. These agglomerates are particularly suitable for uses in gas-phase and/or liquid-phase adsorption processes.
US09744517B2 Reactor with cold turning plasma and stream forcing
A reactor for forming a plasma in a flowing fluid that includes a central rod belonging to a first electrode, an insulator, a tubular body belonging to a second electrode and defining a cylindrical space for the flow of the fluid between the tubular body and the insulator. The reactor further includes control disk having a front face linked to a downstream end of the central rod, and a permanent magnet juxtaposed against a back face of the control disk. One or more ribs are on a front face of the control disk according to a pattern in relief defining successive starting points for an electric arc distributed around the central axis of the reactor so as to generate electric arcs situated on a reaction cone and appearing to turn around the central axis.
US09744516B2 Processing device and processing method
A processing device and processing method that can perform processing of a starting material fluid while favorably controlling the processing temperature of same. The processing device includes: a processing member that leads in the starting material fluid and processes same therewithin; and a processing tank that houses the processing member and retains the processed processing products. The processing member includes: a minute duct provided therewithin and causes the flow-through of the starting material fluid; and a heat medium duct that causes the flow-through of a heat medium having a different temperature from that of the starting material fluid flowing through the minute duct. The minute duct and the heat medium duct are separated from each other so that heat exchange is possible between the starting material fluid and heat medium flowing through.
US09744512B2 Gelator and organogel
There is provided a novel gelator which enables formation of gel by a simpler technique. A gelator including two or more alkylamide compounds of General Formula [I]: (where R1 is a C1-30 aliphatic group optionally having a substituent) or two or more alkylurea compounds of General Formula [II]: (where R2 is a C1-30 aliphatic group optionally having a substituent), wherein the gelator forms a gel exhibiting thixotropic properties.
US09744510B2 Nitric oxide generator and non-deliquescent tablet for use in same
An apparatus to generate nitric oxide is disclosed in one embodiment in accordance with the invention as including a heat source and a vessel containing the heat source. A tablet may be placed within the vessel such that it is in thermal communication with the heat source to receive heat therefrom. The tablet may contain reactants that are substantially non-deliquescent and form nitric oxide in response to heat from the heat source.
US09744509B2 Chemical carbon dioxide gas generator
A chemical carbon dioxide gas generator comprising: a charge housing; a carbon dioxide gas penetrable charge, contained in the said housing, the charge comprising a) 40-60 wt. % of a substance which upon decomposition generates carbon dioxide, which substance is selected from the group of magnesium carbonate, other carbonates, magnesium oxalate and other oxalates, b) 20-50 wt. % of an oxidiser selected from the group of sodium chlorate, potassium chlorate, lithium chlorate, other metal chlorates, sodium perchlorate, potassium perchlorate, lithium perchlorate, and other metal perchlorates, c) 1-20 wt. % of carbon or another fuel, d) 1-10 wt. % binder, said components a), b), c) and d) together forming 90-100 wt. % of the total weight of the charge; an ignition device for igniting the charge; a carbon dioxide gas treatment unit for reducing the content of one or more side-products—which may have been formed by the charge—in the generated carbon dioxide, and/or for cooling carbon dioxide gas generated by the charge; and an outlet for carbon dioxide gas generated by the charge.
US09744508B2 Apparatus for revaporizing gas hydrate pellets
The present invention provides an apparatus for regasifying gas hydrate pellets that includes: a cylinder; a piston coupled to an inside of the cylinder and configured to reciprocate up and down; a pellet providing part coupled to an one side of the cylinder in such a way that supply of gas hydrate pellets to the cylinder is adjusted by having one end thereof opened and closed by reciprocation of the piston; a pressure adjusting space having one end thereof coupled to a lower portion of the cylinder; a door formed in the pressure adjusting space and configured to define the pressure adjusting space; a transfer part having one end thereof coupled to the other end of the pressure adjusting space and configured to transfer the gas hydrate pellets; and a regasification part coupled to the other end of the transfer part and having heating water therein to allow regasification of the transferred gas hydrate pellets.
US09744506B2 Instruments for mixing the contents of a detection chamber
A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.
US09744489B2 Phase separator using pressure differential
A separator for a gas stream has a horizontal tank with a fluid inlet, a fluid outlet and a flow path along the inside of the horizontal tank. A flow barrier is disposed within the tank between the inlet and the outlet. One or more sets of liquid ports are in fluid communication with the tank and positioned at a bottom surface of the tank. Each set of liquid outlets has a first port and a second port. The first port is positioned upstream along the flow path relative to the second port. A fluid passage is in fluid communication with the first port and the second port. The fluid passage defines a secondary flow path adjacent to the horizontal tank, where the first port acts as a draft inlet to the secondary flow path and the second port acts as a draft outlet from the secondary flow path to the tank.
US09744488B2 Filtration system
The filtration system having a housing having an inlet, at least one outlet being axially spaced from the inlet and forming a helical purge path therebetween, and a filtrate outlet extending out along the axis, with a flow rate ratio being balanced by flow restriction between the filtrate outlet and the at least one purge outlet during regular operation; a filter element including a filtration membrane and a support membrane mounted concentrically around the axis, at least one of said filtration membrane and support membrane being rotatably mounted to the housing for rotation about the axis to impart a relative rotation speed between the filtration membrane and support membrane during operation; the system being operable to temporarily increase the flow rate ratio through the at least one outlet compared to said regular operation.
US09744486B2 Filter device
A filter device has filter elements (23) received in a filter housing (1) with a filter inlet (19) and a filter outlet (21). Flow passes through the filter elements (23) for a filtration or backwash in both directions. At least one filter element (23) performs the filtration. At least one other filter element (23), for cleaning off its active filter surface, can be backwashed by a backwash appliance. For supporting the backwashing, the appliance contains a pressure control (43) having a pressure control element (45). During a backwash operation, the fluid flow is controllable in a fluid connection between filter inlet (19) and the filter element (23) that is to be cleaned off. The fluid connection has a connection space (29) having element openings (27), each of which can be connected to an open end of the filter cavity forming the unfiltered side of each filter element (23). A fluid pathway (27) is provided via which, during the filtration, unfiltrate flows into the connection space (29). By the pressure control element (45), the flow of unfiltrate through the element opening (27) associated with the filter element (23) that is to be cleaned off can be controlled.
US09744483B2 Large scale acoustic separation device
Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end of the acoustic chamber. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the acoustic chamber that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet, and the particulates are collected via the concentrate outlet. The device is a large-scale device that is able to process liters/hour, and has a large interior volume.
US09744480B2 Apparatus and methods for changing the concentration of gases in liquids
Apparatus, and components for use in apparatus, for changing the concentration of a selected gas in a liquid, for example for degassing liquids. In one apparatus, the apparatus has a flow channel (a) through which the liquid is passed, and (b) which comprises a wall comprising a planar separation membrane, and (c) has a height of 0.00025-0.01 and an aspect ratio (width to height) of at least 25:1. One component, which can be used to support a separation membrane, comprises (a) an inner selection plate surface which comprises (i) a selection plate base and (ii) selection plate elements which (a) extend from the base, (b) are separated by intercommunicating selection areas, and (c) have outer surfaces remote from the selection plate base. Another component is a planar separation membrane which comprises (a) a membrane transmission section, and (b) a membrane peripheral member which surrounds the membrane transmission section and which includes location features which facilitate the location of the membrane at a desired position relative to another component.
US09744477B2 Purge method for low pressure gradient formation liquid chromatography
Described is a method for purging a fluid channel is a low pressure gradient formation liquid flow system. Control of the fluid channels for multiple solvents allows for one or more static volumes of solvents not intended for use in an isocratic flow to be purged from their fluid channels to avoid contamination of the isocratic solvent. Advantageously, the method avoids the need to modify equipment or to reconfigure a pumping system so that the inlet is directly coupled to a single solvent source. Thus there is no need to bypass existing valves and liquid coupling components where solvents are combined during conventional gradient operation.
US09744476B2 3D printed modular centrifugal contactors and method for separating moieties using 3D printed optimized surfaces
The present invention provides an annular centrifugal contactor, having a housing to receive a plurality of liquids; a rotor inside the housing; an annular mixing zone, with a plurality of fluid retention reservoirs; and an adjustable stem that can be raised to restrict the flow of a liquid into the rotor or lowered to increase the flow of liquid into the rotor. The invention also provides a method for transferring moieties from a first liquid to a second liquid, the method having the steps of combining the fluids in a housing whose interior has helically shaped first channels; subjecting the fluids to a spinning rotor to produce a mixture, whereby the channels simultaneously conduct the mixture downwardly and upwardly; and passing the mixture through the rotor to contact second channels, whereby the channels pump the second liquid through a first aperture while the first fluid exits a second aperture.
US09744475B2 Butadiene extraction process
A process for recovering 1,3-butadiene from a C4 fraction, where the butadiene extraction processes may be operated at an intermediate pressure using a liquid ring type compressor. The use of a liquid ring compressor, among other process options presented herein, may advantageously reduce capital and operating costs, similar to the compressorless option, while mitigating the risks associated with the higher operating temperatures and pressures associated with the compressorless option. Thus, the embodiments of the processes disclosed herein encompass the best features of the conventional design (low pressure, with a compressor) with the advantages of the compressorless design (low capital and operating cost), as well as other advantages unique to the systems disclosed herein.
US09744472B2 Modular illuminated decorative article
An illuminated modular decorative article includes a base control panel and a side panel. The base control panel includes a base, a first electrical/mechanical connection interface, and a power source. The side panel includes a base, a second electrical/mechanical connection interface, and illumination sources. The first electrical/mechanical connection interface connects to the second electrical/mechanical connection interface to electrically connect the base control panel to the side panel and to mechanically connect the base control panel substantially orthogonally to the side panel.
US09744471B1 Laminar jets for water play structures
The present disclosure provides a water play feature that creates a laminar water jet stream, or multiple laminar water jet streams for interaction and display in a water park.
US09744470B2 Distributed feeding device and control system of model vehicle
To suppress unintended rapid acceleration of a vehicle and the like while suppressing a wire length of a feeding system in the entire layout in section-divided feed using pulse width modulation. A clock generation unit included in a feeding device generates an internal clock having a phase aligned based on a reset signal supplied from a higher-level device that controls a vehicle speed of the vehicle, the reset signal being commonly supplied to another feeding device. A pulse width modulation unit counts the internal clock, and generates a pulse having a pulse width (duty ratio) according to an instruction of the vehicle speed from the higher-level device based on the count value. A driver supplies a pulsed drive voltage having the duty ratio, to which the pulse width modulation has been applied by the pulse width modulation unit, to a section allocated to the driver.
US09744467B2 System and method for enhanced video of game playback
One aspect of the disclosure relates to facilitating the development and provision of enhanced video of game playback, including the ability to augment a video of game playback with information relating to the game state of the game. A video may be generated based on game state information associated with one or more selected portions of the game. The video may include visual features that may not have been present in corresponding views that were presented to the user during game play of those one or more portions of the game. The user may augment the video with displayed information based on game logic for the online game. For example, displayed information may include commentary, tips on how the user could have maximized his game play, influential plays from the one or more portions of the game, and/or other information based on the game logic.
US09744466B2 Widgetized avatar and a method and system of creating and using same
An upsell engine that provides a purchaser of a first item the opportunity to purchase a second item that is related to said first item. The first item may be a virtual item and the second item may be a real world item related to or a representation of the virtual item. The upsell engine preferably tracks the preferences or personal information of the user in order to upsell real world representations of the virtual item.
US09744465B2 Identify plug-in of EMU class internet game
An Emulator (EMU) configures a monitoring condition relevant with critical data of a game role, when the monitoring condition is met, the EMU transmits the critical data of the game role to a server; the server analyzes the critical data of the game role; when determining that the critical data of the game role is unusual, the server determines that the game role has used a plug-in.
US09744463B1 Apparatus, method and system for crew mechanics in multiplayer games
The APPARATUS, METHOD AND SYSTEM FOR CREW MECHANICS IN MULTIPLAYER GAMES (hereinafter “CMMG”) the CMMG platform transforms in game status of a user's social content item via CMMG components into a content item with layered integration of additional content indicative of status.
US09744461B1 System and method for object weakpoint generation
Systems and methods are provided for dynamic calculation of weakpoints in objects during gameplay. A player strikes an object and a weakpoint appears somewhere on the surface of the object. If the player strikes that weakpoint, the weakpoint disappears, and the amount of damage imparted to the object is some multiple (or factor) of the normal damage imparted. The player's camera position and direction is used to find points on the surface of the object that was struck. The position and direction of the player's camera is used to ensure that the player will be able to see any weakpoint that might be created. The points on the object are recorded. The recorded points are compared against each other and the best point is chosen based on certain criteria.
US09744458B2 Method for simulating video games on mobile device
A system and method for providing players with real-time information on any device capable of running a web browser is provided. The system solves the problem of game interface overloads and also brings the following benefits: provides for control optimization and for more options for a team game play. A usual game play experience is completely simulated on any remote mobile device by allowing remote input of the game controls from the mobile device to the base platform (PC/MAC, etc) and streaming the video from the base platform to the mobile device. The mobile device acts as a “thin client” for the base platform. Adoption of the game to the mobile device is not required.
US09744453B2 Methodology for equalizing systemic latencies in reception in connection with games of skill played in connection with an online broadcast
A method of and system for handling latency issues encountered in producing real-time entertainment such as games of skill synchronized with live or taped televised events is described herein. There are multiple situations that are dealt with regarding latencies in receiving a television signal with respect to real-time entertainment based on the unfolding games played along with the telecasts. Systemic delays, arbitrarily imposed delays of a broadcast signal and variances in the precise broadcast times of taped television programs have to be equalized so as to provide fair entertainment.
US09744451B2 Apparatus and method for managing user inputs in video games
A system that incorporates teachings of the present disclosure may include, for example, a computing device having a controller to obtain a user input that was inputted into a first accessory operably coupled with the computing device where the first accessory provides a user interface for user interaction with a video game, determine a language of an intended recipient of the user input based on an identity of the intended recipient, access a multi-lingual library comprising a plurality of words associated with the video game, match the user input to one or more words of the plurality of words of the multi-lingual library to generate a translated message in the determined language of the intended recipient, and provide the translated message to a second accessory for presentation to the intended recipient in real-time. Additional embodiments are disclosed.
US09744450B2 System and method for virtual team assembly
A collection of data corresponding to a player is assembled at a server from a data provider. A base value of the player based on at least the primary data is added as an attribute to an internal object stored at the server. A modifier is mapped to a second attribute of the internal object. The modifier is based on at least a portion of the secondary data and the tertiary data. A projected value is generated from the base value by applying a modifier and a rule converting the modified second attribute to a projected value. Internal objects are generated according to constraints including having a sum of limiting factors of the internal objects that does not exceed a maximum factor and a sum of projected values a maximum, subject to the first constraint. The server transmits application data including a list representing the internal objects.
US09744445B1 System and method for providing awards to players of a game
One aspect of the disclosure relates to a multi-prize mystery box that provides an award to users who activate the mystery boxes and benefits to members of affiliations associated with the activating users. Users of an association may be provided notifications informing the users that the activating user has provided them with a benefit, increasing recognition of the activating user in the game.
US09744443B2 Server, terminal, network system, program and information storage medium
A server is connected to a terminal via a network, and manages registration of game information, the terminal performing a first game process that utilizes stored game information, and a second game process that utilizes registered game information. The server stores terminal identification information of the terminal and an allowable registration count of the terminal in a linked manner, updates the allowable registration count while being linked to the terminal identification information corresponding to a received update allowable registration count, transmits a registration permission notification to the terminal upon reception of a game information registration request from the terminal when the allowable registration count is equal to or larger than a given number, transmits a registration non-permission notification to the terminal when the allowable registration count is less than the given number, and decrements the allowable registration count when the server has transmitted the registration permission notification to the terminal.
US09744440B1 Generating game configurations
A system, computer-readable storage medium storing at least one program, and a computer-implemented method for generating game configurations are presented. For example, a system may receive a game configuration request message from a client device being operated by a player playing a virtual game. The game configuration request message may be sent, for example, in response to the player initiating a new game of the virtual game. The system may then select a game configuration based at least in part on historical performance data associated with the selected game configuration. The historical performance data may accumulate performance data from a group of players that previously played the virtual game using the selected game configuration. The system then communicates the selected game configuration to the client device. The player may play the virtual game using the selected game configuration as the initial game configuration for the virtual game.
US09744438B2 Talent portfolio simulation
A talent management portfolio game including a board representing an organization, whereby game pieces representing members of the organization having a potential value to the organization can be managed so as to maximize the value of the organization according to its members. Value pieces representing realized potential can be attached to the game pieces based on played talent action cards, thereby realizing some of the potential of the game piece. Game pieces can be promoted within the organization or exchanged in attempts to maximize the value of the organization.
US09744437B2 Automated card shuffling and dealing device
An automated playing card, shuffling and dealing device in turn shuffles and in turn deals playing cards of two playing card sets, includes two card slot assemblies each disposed with a shuffled card box and a dealt card box. A control unit controls a dealing element to align with the playing card set in the shuffled card box of the card slot assembly at a card drawing position, sequentially draw the cards in the playing card set, and move the uncovered cards to the corresponding dealt card box. Meanwhile, the control unit controls a shuffling machine to align with the playing card set in the dealt card box of the card slot assembly at a card shuffling position. After the dealing process is complete, the control unit exchanges the positions of two card slot assemblies. Accordingly, shuffling and dealing in turn are completed in an uninterrupted and automated manner.
US09744426B2 Electronic device and method for controlling the electronic device
A method for adjusting a working state of an electronic device includes setting a reasonable value range of feature data of a user, and acquiring current feature data of the user from the camera device. The current feature data is compared to the reasonable value range of feature data. A working state of the electronic device is changed when the current feature data is out of the reasonable value range of feature data.
US09744425B2 Travel cover with a swivel handle
A swivel handle capable of rotating or swiveling is disclosed. The swivel handle comprises a handle that is capable of rotating relative to a base plate or an enclosure or other object to be pulled. The swivel handle may further comprise a rotatable plate wherein the handle is connected to the rotatable plate, a rotational locking assembly, and/or a braking assembly.
US09744424B1 Scheduling system
The present disclosure relates to a novel scheduling system and in particular, a system for scheduling matches, practices, and related activities. The novel system includes a non-transitory machine readable storage medium containing instructions to cause a machine to generate a line-up for a match between at least two sports team; generate a food assignment for the match; generate a practice schedule for each sport team; and generate a series of line-ups for a season of play. Additionally, the non-transitory machine readable storage medium further contains instructions to cause a machine to generate a ranking of each sport team based on a record of each sports team.
US09744422B2 Recommendation engine
Generally, described are methods, apparatuses and systems for a recommendation engine which determines a recommendation based upon a terrestrial parameter and an overall factor unrelated to the terrestrial parameter. The recommendation engine may receive as inputs: (1) some data relating to the terrestrial parameter and (2) some data relating to user operation of a mechanical device. An overall factor may be calculated or obtained, at least in part, from the data relating to user operation of the mechanical device. And based upon the data relating to the terrestrial parameter and the overall factor, a recommendation may be determined and transmitted. In one embodiment, as part of the transmission process, the recommendation may be displayed to a user requesting the recommendation.
US09744421B2 Method of analysing a video of sports motion
A method, apparatus, system and computer program product for analyzing video images of a sports motion is provided for identification of key motion positions within a video and automatic extraction of segments of a video containing a sports motion. Video data displaying a sports motion has data representative of a number of image frames. For a number of image frames, one or more frame difference measures are calculated between the image frame and another image frame. The frame difference measures are analyzed to identify a plurality of image frames that each show a key position of the sports motion. The segment of the video containing the sports motion showing the sports motion is between two of the image frames showing the key positions. Frame difference measures may be calculated based on pixel difference measures or optical flow techniques.
US09744419B1 Vision training system and method of use
Devices, systems, and methods for training baseball and softball batters, to identify types of pitched balls (fast ball, curve ball, slider and changeup) and locations (strike or non-strike zone) of pitched balls in order to increase hitting accuracy A motion sensor can be triggered by the leading foot of a pitcher. The motion sensor can use cone or fan shaped sensor to detect the passage of a pitched ball from the pitcher. When the motion sensor is triggered, a signal can be sent to a black out lens that blocks the vision of a hitter being trained to identify the types and locations of the pitched balls. The training includes changing the lens from transparent to opaque at selected distances between the hitter and the pitcher. Batters can be trained to keep their eyes on the pitched balls until the ball reaches the batter. Golfers can be trained to not have to look up when their club hits the ball, where the black out lens are go opaque when the golf swing passes into the motion sensor.
US09744412B2 Golf club head or other ball striking device having impact-influencing body features
A ball striking device, such as a golf club head, has a face with a striking surface configured for striking a ball and an elongated channel extending across a portion of the sole in a heel to toe direction. The channel is recessed from adjacent surfaces of the sole. The channel may have a width defined in a front to rear direction and a depth of recession from the adjacent surfaces of the sole, wherein the channel comprises a center portion extending across a center of the sole, a heel portion extending from a heel end of the center portion toward the heel, and a toe portion extending from a toe end of the center portion toward the toe. The channel may have a wall thickness that is greater in the center portion of the channel than in at least one of the heel and toe portions.
US09744411B2 Releasable and interchangeable connections for golf club heads and shafts
Golf club heads are releasably engaged with shafts so that the club heads and shafts can be readily interchanged and/or so that the shaft position with respect to the club head can be readily changed. Assemblies for connecting the club head and shaft may include: a shaft adapter, a collet, a ferrule, and a club head having an interior chamber. The club head and shaft may be changed by releasing the securing system and exchanging the original parts with different parts.
US09744405B2 Golf ball having comma-shaped dimples
In a golf ball including dimples having comma shapes, the dimples are arranged such that one comma shaped dimple replaces a circular dimple, two or more comma shaped dimples of different sizes replace one circular dimple, comma shaped dimples having different shapes are arranged in a mixed type arrangement, circular dimples and comma shaped dimples are arranged in a mixed type arrangement, or a discontinuous annular dimple is added to the comma shaped dimples. Thus, a disadvantage of a large circular dimple may be removed and simultaneously a golf ball with stable flight capability and a long flight distance may be provided.
US09744403B2 Activity tracking racquet attachment device
An activity tracking racquet attachment device tracks activity such as calories burned over a period of using a racquet to which the device is attached. The device includes a housing having a first face and a perimeter sidewall extending from and around the first face. A processor is coupled to the housing. A motion detector is coupled to the housing such that the motion detector detects movement of the housing. The motion detector is communicatively coupled to the processor wherein the processor receives motion data from the motion detector. A coupler is coupled to and extends from a second face of the housing coupling the housing to an end of a handle of a racquet such that the first face of the housing faces outwardly from the end of the handle.
US09744398B1 Hand-held weights with optional deterrent devices
A hand-held exercise weight system has integral self protective features within each weight system. Each weight system has an activation button located near the user's thumb. One (1) weight system is equipped with a loud audible alarm to signal for help in times of duress. The other weight system is equipped with an ultrasonic dog repellent system, which deters any possible attacking canines. Each weight system is provided with a user replaceable battery, and is self-contained and waterproof. Each weight system has a weighted body that is detachable from the system.
US09744395B1 Pilates machine tension device support system
A Pilates machine tension device support system for efficiently providing a tension force to a movable platform of an exercise machine. The Pilates machine tension device support system generally includes a frame, a platform movably positioned upon the frame and a tension assembly connected between the frame and the platform to provide selective tension upon the platform in a first direction. The tension assembly is comprised of a plurality of pulleys and a plurality of tension devices positioned upon the pulleys, wherein the tension devices are attached between a frame and the platform. The tension members are selectively engaged to the platform to increase or decrease the tension applied to the platform for varying levels of workouts.
US09744392B1 Compounds and methods for the reduction of halogenated hydrocarbons
The present application relates to methods for the reduction of halogenated hydrocarbons using compounds of Formula (I): wherein the reduction of the halogenated compounds is carried out, for example, under ambient conditions without the need for a transition metal containing co-factor. The present application also relates to methods of recovering precious metals using compounds of Formula (I) that are absorbed onto a support material.
US09744390B2 Dry sprinkler with a diverter seal assembly
A dry sprinkler is provided that includes a structure, a fluid deflecting structure, a locator, a metallic annulus and a shield. The structure defines a passageway extending along a longitudinal axis between an inlet and an outlet. The structure has a rated K-factor defining an expected flow of fluid in gallons per minute from the outlet divided by the square root of the pressure of the flow of fluid fed into the inlet of the passageway in pounds per square inch gauge. The fluid deflecting structure is proximate the outlet. The locator is movable along the longitudinal axis between a first position and a second position. The locator supports the metallic annulus. The metallic annulus includes first and second metallic surfaces spaced apart along the longitudinal axis between an inner and outer circumference with respect to the longitudinal axis. The shield has a first face exposed to the inlet and a second face confronting the first metallic surface to define a gap there between. Various methods are also described.
US09744388B2 Compressed air foam system with simplified user interface
A one-touch Compressed Air Foam System (CAFS) is provided that allows for a simplified user interface and simplified user operation. The user interface allows the CAFS to activate upon a single press of a single button. An electronic controller checks that several CAFS device parameters show that the CAFS is capable of operating. The controller gathers the device parameter data from a diagnostic system present in the CAFS that gives data pertaining to whether water is flowing, whether foam concentrate is present in the system, whether foam is flowing, and whether the temperature of an air compressor is within a safe range for operation. If the above device parameters are found to be in condition for safe operation of the CAFS, the controller will start and maintain operation until either one of the above falls out of tolerance or the user initiates a shut down of the CAFS.
US09744384B2 Enhanced display for breathing apparatus masks
Various embodiments provide a self contained breathing apparatus mask including a visor, a wireless communication device configured to receive information, and a display connected to the wireless communication device and configured to display the received information to a user wearing the mask. The display may be positioned on the breathing apparatus mask such that the user may simultaneously see the display and look through the visor.
US09744383B2 Rope descent device and method
A rope descent device and method capable of maintaining a fast but safe descent rate of a user carrying a heavy load or equipment.
US09744382B2 Cosmetic and dermatological preparations containing carnitine for treating and actively preventing dry skin and other negative alterations in the physiological homeostasis of healthy skin
A cosmetic or dermatological composition which comprises carnitine, a precursor thereof, a metabolite thereof and/or a derivative thereof.
US09744380B2 Patient specific beam control assembly of a cancer therapy apparatus and method of use thereof
The invention comprises a patient specific tray insert removably inserted into a tray frame to form a beam control tray assembly, which is removably inserted into a slot of a tray receiver assembly proximate a gantry nozzle of a charged particle cancer treatment system. Optionally, multiple tray inserts, each used to control a different beam state parameter, are inserted into corresponding slots of the tray receiver assembly where the multiple inserts are used to control beam intensity, shape, focus, and/or energy. The beam control tray assembling includes an identifier, such as an electromechanical identifier, of the particular insert type, which is communicated to a main controller, such as via the tray receiver assembly along with slot position and/or patient information.
US09744377B2 Light therapy platform system
Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly including a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed so that the reflective surface is relatively smooth and seamless towards the patient. The walls have a malleable rigidity for flexible adjustability relative to the user, and the device is mounted to the user with a frame.
US09744370B2 AED having CPR period with pause for ECG acquisition
A method for using a defibrillator is described which executes a resuscitation protocol having a CPR pause period. The defibrillator prompts a rescuer to perform CPR during a CPR pause period. The CPR pause period may be interrupted for the acquisition of ECG signal data which is not contaminated by chest compression artifacts. Following the acquisition of ECG signal data, the CPR period resumes and continues for its full period. The ECG signal data acquired during the interruption of the CPR period is analyzed and, if a shockable rhythm is identified, a shock sequence is initiated immediately upon conclusion of the CPR period.
US09744364B2 Method and apparatus for automatic configuration of implantable medical devices
A system including a programmable implantable monitoring device and a programmer for programming the device and a method of use thereof. The programmer may be configured to transmit programming commands responsive to entry of a reason for monitoring to the implantable device including a prioritization of an arrhythmia storage criterion. The implantable may be configured to thereafter store and/or transmit records of the arrhythmia according to the prioritization. The programmer may be configured to transmit the patient's age to the implantable device and the implantable may be configured to thereafter apply arrhythmia detection criteria based upon the patient's age.
US09744363B2 Non-regular electrical stimulation patterns for treating neurological disorders
Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.
US09744360B2 Selective stimulation systems and signal parameters for medical conditions
Devices, systems and methods are provided for targeted treatment of a variety of conditions, particularly conditions that are associated with or influenced by the nervous system, such as pain. Targeted treatment of such conditions is provided with minimal deleterious side effects, such as undesired motor responses or undesired stimulation of unaffected body regions. This is achieved by directly neuromodulating a target anatomy associated with the condition while minimizing or excluding undesired neuromodulation of other anatomies.
US09744358B2 System and method for neural cochlea stimulation
A system having a device for neural stimulation of a patient's cochlea, an in-situ device for measuring a patient's response to the neural stimulation of the cochlea, and a programming unit for adjusting the stimulation device; the stimulation device having a stimulation signal unit for generating a stimulation signal formed of pulses having a shape determined by a shape parameter set including at least one shape parameter; a cochlear implant stimulation arrangement with a plurality of stimulation channels for stimulating the cochlea based on the stimulation signal; the measuring device providing patient-specific response data concerning the stimulation response to a programming unit that controls the stimulation signal unit by subsequently supplying a plurality of different test shape parameter sets to the stimulation signal unit for causing the stimulation signal unit to generate corresponding test pulses, the programming unit evaluating each test shape parameter set based on stimulation response data.
US09744354B2 Obstructive sleep apnea treatment devices, systems and methods
Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
US09744349B2 Medical lead and implantation
A lead for navigating small vessels and a catheter system for implantation of leads into small vessels. Veins that return blood to the heart against the force of gravity often have valves in them to prevent backflow of deoxygenated blood. Leads and catheter systems in accordance with embodiments of the invention allow cannulation and lead implantation in small, tortuous, obstructed, and difficult to access veins enabling a range of stimulation and sensing applications.
US09744347B2 Systems and methods for reducing power consumption in an implantable medical device
A medical device for providing a stimulation therapy includes stimulation circuitry configured to provide a plurality of electrical pulses to be delivered to a patient. The stimulation circuitry contains a microcontroller configured to generate the electrical pulses. Each electrical pulse includes a primary phase, an interphase after the primary phase, and a recovery phase after the primary phase. Consecutive electrical pulses are separated by a standby period. The microcontroller is configured to operate in an active mode during at least one of: the primary phase and the interphase. The microcontroller is configured to operate in a power-conservation mode during a substantial majority of the standby period. The microcontroller consumes substantially less power when operating in the power-conservation mode than in the active mode.
US09744345B2 Leads with proximal stiffening and related methods of use and manufacture
An electrical stimulation lead includes a lead body; electrodes disposed along the distal portion of the lead body or on a paddle body coupled to the lead body; terminals disposed along the proximal portion of the lead body; and conductors coupling the terminals to the electrodes. The lead also includes a conductor guide disposed within the lead body and extending from the proximal portion of the lead body. The conductor guide defines a central lumen and a plurality of conductor lumens disposed around the central lumen. The lead further includes a stiffening agent disposed within at least one of the conductor lumens. The stiffening agent includes a) a material formed from a granular particulate material, b) a polymeric material having a durometer at least 10% greater than the durometer of the conductor guide, or c) a continuous epoxy layer within which discrete epoxy particles are also disposed.
US09744344B1 Devices and methods for catheter placement within a vein
An apparatus includes an introducer defining a lumen and a catheter movably disposed in the lumen. The introducer has a distal end portion configured to operably couple to an indwelling peripheral intravenous line at least partially disposed in a vein. The catheter is configured to be moved between a first position, in which the catheter is proximal to the peripheral intravenous line when the introducer is operably coupled thereto, and a second position, in which a distal surface of the catheter is distal to the introducer and disposed at a predetermined distance from a distal tip of the peripheral intravenous line. The predetermined distance defined between the distal surface of the catheter and the distal tip of the peripheral intravenous line is based at least in part on a venous anatomy associated with the vein.
US09744341B2 Devices and methods for intraluminal retention and drug delivery
Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.
US09744335B2 Apparatuses and methods for monitoring tendons of steerable catheters
Methods and apparatuses for detecting tension on a tendon and/or mechanical deformation (e.g., breakage) of one or more steering tendon of a steerable and flexible articulating device. Theses apparatuses may have one or more tendons that are each electrically conductive and configured to steer the apparatus when tension is applied to the proximal end of the tendon. Tension and/or breakage (or other deformation) of one or more of these tendons may be detected by monitoring the electrical resistance of the tendons.
US09744329B2 Air filtration device having subsections lacking fluid communication
A filtering device 10 that includes a housing 12 having a plurality of subsections 32, 34, and 36 where each subsection contains a filter element 26, 28, and 30. An inlet 18 is disposed at a first location on the housing 12, and an upstream air distribution system is placed in fluid communication with the inlet 18 and with each of the subsections 32, 34, and 36. A downstream air distribution system is located in fluid communication with each subsection 32, 34, and 36, and an outlet 20 is in fluid communication with the downstream air distribution system. The subsections are fashioned such that each subsection 32, 34, and 36 is not in fluid communication with each other. Using a filtering device so constructed, airflow through the device may be better managed to enable overall product service life to be increased while minimizing pressure resistance of the total filter.
US09744328B2 Air filtration device having tuned air distribution system
A filtering device 10 that includes a housing 12 having a plurality of subsections 32, 34, and 36 where each subsection is adapted to receive a filter element 26, 28, and 30. An inlet 18 is disposed at a first location on the housing 12, and an upstream air distribution system is placed in fluid communication with the inlet 18 and with each of the subsections 32, 34, and 36. A downstream air distribution system is located in fluid communication with each subsection 32, 34, and 36, and an outlet 20 in fluid communication with the downstream air distribution system. The upstream and downstream air distribution systems are constructed to cause the same airflow velocity through each subsection. Using such a construction, overall product service life may be increased while minimizing pressure resistance of the total filter.
US09744317B2 Seal anchor with non-parallel lumens
A seal anchor member defines a housing defining a longitudinal axis, the housing having leading and trailing ends, and including a plurality of lumens extending between the leading and trailing ends, each lumen being adapted for substantially sealed reception of an object therein and defining a longitudinal axis, wherein at least two of the lumens define longitudinal axes that are non-parallel to facilitate angled, at-rest placement of multiple instruments within the seal anchor member.
US09744312B2 Methods and apparatus for lancet actuation
A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet along a path into the tissue site, and a manual switch for a user interface input.
US09744311B2 Injection device with dose display for signaling the end of the injection
Drive and metering devices for injection devices include a dose display element with a helical dosage scale; an indicating means; a metering member, which can be rotated relative to the indicating means for dose setting; a discharge spring and an advancement member. The dose display element can be screwed relative to the indicating means about a longitudinal axis (L) and a value on the dose scale can be read via the indicating means corresponding to the set dose. The discharge spring causes the advancement member to discharge the product as it moves an overall discharge stroke length (Hg), where the overall discharge stroke length (Hg) comprises a first partial discharge stroke length (H1), during which the dose display element is rotationally secured in relation to the indicating means and where the dose display element can be rotated relative to the indicating means following the first partial discharge stroke length (H1).
US09744310B2 Pharmaceutical injection device
The pharmaceutical injection device includes a pharmaceutical syringe mounting portion (3) provided within a main body case (2) and to which a pharmaceutical syringe (4) is removably mounted, a piston (5) provided movably with respect to the pharmaceutical syringe (4) mounted to the pharmaceutical syringe mounting portion (3), a drive mechanism (6) for driving the piston (5), a controller (7) that is electrically connected to the drive mechanism (6), a display section (35) that is connected to the controller (7), and an encoder (26) that is connected to the controller (7) and detects the amount of the pharmaceutical remaining inside the pharmaceutical syringe (4). The controller (7) displays a warning on the display section (35) recommending removal of the pharmaceutical syringe (4) from the pharmaceutical syringe mounting portion (3) when the presence of a pharmaceutical is detected by the encoder (26).
US09744309B2 Medicament delivery device
The present invention relates to a medicament delivery device that is reliable, safe and intuitive to use and configured to prevent a subsequent does from being administered before a previously initialized dose has been fully delivered. This is accomplished by mechanically interacting structures arranged as an interface between a lockable delivery button and a release member.
US09744308B2 Medicament delivery device
A dose setting mechanism for a medicament delivery device is presented having a pinion mounted to a locking member where the axis of rotation of the pinion is offset and parallel to the longitudinal axis of the housing containing the dose setting components. Primary and secondary dose members are engaged with the pinion to indicate a set dose of medicament.
US09744307B2 Medicament delivery device
A dose setting mechanism for a medicament delivery device is presented having a pinion mounted to a locking member where the axis of rotation of the pinion is offset and parallel to the longitudinal axis of the housing containing the dose setting components. Primary and secondary dose members are engaged with the pinion to indicate a set dose of medicament.
US09744306B2 Injection devices
An injection device includes an injection complete indicator which includes its own bias and which is latched into a retracted position as the injection device is cocked. Upon firing the injection device, the injection complete indicator is kept in its retracted position until towards the end of the forward stroke of the drive mechanism, whereupon the injection complete indicator is unlatched and shoots forwardly under the influence of the bias to impact an abutment to generate an audible/tactile indication along with a visual indication.
US09744305B2 Quick release plunger
A stopper configured to slidably move within the hollow lumen of a syringe to facilitate movement of fluid within the syringe. The stopper includes a base and one or more capture members extending rearwardly from the base. The one or more capture members each include a beveled edge configured to interact with a piston of a fluid injection apparatus, wherein the one or more capture members are radially deflected upon rotation of the stopper relative to the piston to facilitate removal of the stopper from the piston. The stopper is configured for slidable movement within a body of a syringe and forms a fluid tight seal with an inner wall of the body of the syringe. Also disclosed is a plunger which includes the stopper.
US09744304B2 Pre-filled syringe identification tag
An assembly includes a pre-filled syringe including a barrel with a first end and a second, open end, a plunger disposed within the barrel and spaced between the first end and the second, open end, a product disposed in the barrel between the first end of the barrel and the plunger, and an outwardly-directed rim disposed about the barrel at the second, open end. In addition, the assembly includes an identification tag secured to the outwardly-directed rim of the barrel of the syringe with an outwardly-facing surface of the tag overlying the second, open end of the barrel, the tag having an identifier disposed on the surface of the tag, the identifier including data regarding the pre-filled syringe, the product disposed in the barrel, or both.
US09744299B2 Data processing device for an anesthesia device
A data processing device is provided for an anesthesia device for feeding an intravenously administered hypnotic, a volatile hypnotic, and an opioid such that the volume flow can be adjusted. The device determines and standardizes the effective concentrations of the anesthetics. A pharmacokinetic model adds up the standardized concentrations of the hypnotics to a total hypnotic concentration. An isobole is calculated based on a coordinate plane with a total hypnotic concentration axis and an opioid concentration axis, as a function of the currently determined concentrations. The system displays a two-dimensional action diagram with the y-axis as an indicator of the total hypnotic concentration and the x-axis as an indicator of the standardized opioid concentration. The calculated standardized total hypnotic concentration and opioid concentration and the isoboles determined are displayed. The display is adapted to changes occurring in the isoboles determined in the course of time.
US09744298B2 Selectively controlling fluid flow through a fluid pathway
Systems and methods for controlling fluid delivery via a manually administrable medication container to a patient through a fluid delivery pathway are provided. The systems and methods described herein incorporate rules-based clinical decision support logic to drive a flow control valve within a flow pathway based on a determination of whether or not an IV fluid connected to an input port on the pathway is appropriate for patient administration by considering such factors as patient-specific clinical circumstances, current medical orders, and accepted delivery protocols. Related apparatus, systems, methods and articles are also described.
US09744295B2 Rotatable infusion set
An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula.
US09744290B2 Smart connection interface
A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.
US09744289B2 Method to determine contrast media injection parameters to control signal intensity during magnetic resonance angiography
Injection systems and related methods including an injection device, an operator interface, and modules to determine operational parameters during an MRA imaging procedure. Such parameters may be used to optimize and/or maximize signal intensity during an MRA imaging procedure. The injection system may include a target in-bloodstream contrast agent concentration determination module that determines a target in-bloodstream contrast agent concentration at least partially based on contrast agent type and MRA imager parameters. The injection system may include a contrast agent injection rate determination module that determines a contrast agent injection rate at least partially based on the target in-bloodstream contrast agent concentration, an initial contrast agent concentration, and a cardiac output rate of a patient to be imaged. The injection system may include a diluent injection rate determination module that determines a diluent injection rate at least partially based on the contrast agent injection rate.
US09744288B2 Systems and methods for performing online extracorporeal photopheresis
Systems and methods for performing online extracorporeal photopheresis of mononuclear cells are disclosed. Whole blood is removed from a patient and introduced through a processing set into a separation chamber to separate the desired cell population from the blood. The separated cell population is processed through the set which is associated with a treatment chamber where the cells are treated. Once treated, the cells are returned to the patient. The processing set remains connected to the patient during the entire ECP treatment procedure and provides an online, sterile closed pathway between the separation chamber and the treatment chamber.
US09744286B2 Connection system for creating a connection channel for bodily fluids
A connection system for creating a vascular cannula for connection to a blood vessel includes a flexible hose element in the form of a graft, a conduit element and, disposed therebetween, a connecting element establishing fluid-tight connections, wherein a retaining element is equipped with a radially outwardly elastically beadable snap ring, which, in the connected state, can be snapped in behind a detent surface of one of the parts of the connection system.
US09744282B2 Smart tip LVAD inlet cannula
Embodiments of the invention provide a left ventricular assist device (LVAD) cannula that includes multiple independent sensors may help decrease the incidence of ventricular collapse and provide automatic speed control. A cannula may include two or more independent sensors. One sensor may measure ventricular pressure, while another may measure ventricular volume and/or ventricular wall location. With this information an automatic control system may be configured to adjust pump speed to minimize the likelihood of ventricular collapse and maximize LVAD flow in response to physiologic demand. Typically the volume sensors are conductance sensors. Further embodiments provide LVADs that are powered by RF energy.
US09744278B2 Wound connection pad with pneumatic connection confirmation ability
A system, apparatus, and method for treating a tissue site with reduced pressure includes a connector having a connector body. The connector body includes a cavity and a cavity aperture. The connector also includes a conduit port fluidly coupling a conduit to the cavity. The connector further includes a base adjacent the cavity aperture that is configured to be positioned adjacent a drape. The cavity is configured to be fluidly coupled to a manifold through an aperture of the drape. The connector also includes a sensing probe having a proximal end configured to be fluidly coupled to the conduit and a distal end extending to the cavity aperture. The distal end is configured to be positioned adjacent to and in fluid communication with a manifold.
US09744274B2 Tissue sampling, processing and collection device and method of using same
Methods of collecting fat tissue samples in tissue collection syringes mounted in an in-line fat sampling device connected to a hand-held power-assisted tissue aspiration instrument.
US09744269B2 Thermoplastic polyurethane admixtures
The invention relates to admixtures of thermoplastic polyurethane base polymers that resist surface dulling and fluorinated additives and their use in the manufacture of articles, such as medical devices. For example, the admixtures of the invention are useful in the manufacture of blood dwelling medical devices, such as catheters.
US09744267B2 Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
US09744264B2 Extracellular matrix encasement structures and methods
A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.
US09744262B2 Alimentary protein-based scaffolds (APS) for wound healing, regenerative medicine and drug discovery
The invention provides engineered biomaterials derived from plant products. The engineered biomaterials are useful for biomedical applications. The engineered biomaterials are able to support the growth of animal calls.
US09744259B2 Implantable medical devices fabricated from branched polymers
Stent scaffolds comprising branched biocompatible polymers are disclosed.
US09744258B2 Diaper lining for treatment of diaper rash
An embodiment of this disclosure provides a medical dressing. The medical dressing includes a first layer comprising a non-woven material capable of being liquid permeable. The medical dressing also includes a second layer comprising a topical composition and a solidifying agent. The second layer is positioned on a side of the first layer. The medical dressing also includes a third layer comprising a material capable of being liquid impermeable. The third layer is positioned on the second layer opposite the first layer.
US09744256B2 Nebulizer system for freshening the air
Nebulizer systems to generate a mist of micro-droplets of a liquid for the purpose of freshening the atmosphere. Nebulizer systems having a small size that can be mounted on a sales stall to humidify and freshen fresh products displayed for sale, or in a vehicle to humidify and freshen the air and make it pleasant to breathe.
US09744255B2 Systems which determine operating parameters and disinfection schedules for germicidal devices
Systems are disclosed which include processor-executable program instructions for receiving data regarding characteristics of a room in which one or more disinfection sources are arranged and determining, based on the received data, individual operating parameter/s for the one or more disinfection sources. Other systems are provided which include processor-executable program instructions for discerning, for each of a plurality of disinfection sources, a target location, region, object or surface within a room in which the disinfection sources are arranged. The systems further include program instructions for comparing the target locations/regions/objects/surfaces and executing corrective actions upon detecting two or more locations/objects/surfaces are within a predetermined distance of each other and/or upon detecting two or more regions overlap.
US09744254B2 Case for sanitizing and transporting tattoo machines
A storage and sterilizing case shaped and dimensioned for storing a tattoo machine therein. The case has a cover and a base. The cover is connected to the base via a hinge securing the cover to the base along adjacent edges thereof. The base includes a tray for supporting the tattoo machine within the case. The interior of the case is provided with an electronic circuit board and at least one ultraviolet light.
US09744249B2 Method and apparatus for kidney function analysis
A method and apparatus for determining physiological data related to an animal, such as kidney diagnostics data, is provided. The method includes injecting a mixture of a first and a second molecule into an animal (e.g., a human patient), determining a molecular ratio of the molecules, and determining the physiological data based on the molecular ratio. The apparatus includes a number of finger receiving apertures, a light generation circuit, a light detection circuit, a pulse counting circuit, and a user interface.
US09744247B2 Functionalized liposomes useful for the delivery of bioactive compounds
The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well.
US09744246B2 Macromolecules
The present invention relates to a macromolecule comprising a dendrimer having surface amino groups to which at least two different terminal groups are attached including a pharmaceutically active agent and a pharmacokinetic modifying agent, the pharmaceutically active agent comprising a hydroxyl group and being attached to the surface amino group of the dendrimer through a diacid linker. Pharmaceutical compositions comprising the macromolecules and methods of treatment using the macromolecules are also described.
US09744234B2 Methods of treating ankylosing spondylitis using IL-17 antagonists
The disclosure relates to novel regimens for treating an inflammatory arthritis, e.g., rheumatoid arthritis (RA) patients, e.g., high risk RA patients, which employ a therapeutically effective amount of an IL-17 antagonist, e.g., 1L-1 7 binding molecule (e.g., IL-17 antibody or antigen binding fragment thereof, e.g., secukinumab) or IL-17 receptor binding molecule (e.g., IL-17 antibody or antigen binding fragment thereof).
US09744230B2 Nucleic acids for treatment of allergies
The present invention provides DNA vaccines for the treatment of allergies. The vaccines comprise the coding sequence for one or more allergenic epitopes, and preferably the full protein sequence, of the allergenic protein from which the epitope(s) is derived, fused inframe with the lumenal domain of the lysosomal associated membrane protein (LAMP) and the targeting sequence of LAMP. The vaccines allow for presentation of properly configured three dimensional epitopes for production of an immune response. The vaccines can be multivalent molecules, and/or can be provided as part of a multivalent vaccine containing two or more DNA constructs.
US09744229B2 Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same
Compositions, recombinant vaccines and live attenuated pathogens comprising one or more isolated nucleic acid molecules that encode an immunogen in combination with an isolated nucleic acid molecule that encodes IL-28 or a functional fragment thereof are disclosed. Methods of inducing an immune response in an individual against an immunogen, using such compositions are disclosed.
US09744227B2 Compositions containing ambient-temperature stable, inactivated but therapeutically active biopharmaceuticals and methods for formulation thereof
The disclosure concerns compositions containing inactivated but therapeutically active biopharmaceuticals, and methods for formulation thereof. Biopharmaceuticals are encapsulated and immobilized in dry amorphous carbohydrate-glass and irradiated for inactivation while in the dry state. The resulting compositions provide ambient-temperature stable, therapeutically active but inactivated biopharmaceuticals for use in vaccines and other applications.
US09744226B2 Attenuated Mannheimia haemolytica strains
The present invention provides attenuated M. haemolitica strains that elicit an immune response in animal against M. haemolitica, compositions comprising said strains, methods of vaccination against M. haemolitica, and kits for use with such methods and compositions. The invention further provides multi-valent vaccines, which provide protective immunity when administered in an effective amount to animals susceptible to “shipping fever” or bovine respiratory disease.
US09744225B2 Surface exposed Haemophilus influenzae protein (protein E; pE)
The present invention relates to a surface exposed protein (protein E; pE), a virulence factor, which can be detected in Haemophilus influenzae, having an amino acid sequence as described in SEQ ID NO 1, an immunogenic fragment of said surface exposed protein, and a recombinant immunogenic protein (pE(A)) or truncated variants thereof based on said surface exposed protein. Nucleic acid sequences, vaccines, plasmids and phages, non human hosts, recombinant nucleic acid sequences, fusion proteins and fusion products are also described. A method of producing the said protein or truncated fragments thereof recombinantly is also disclosed.
US09744219B2 Compositions and methods for treating pathological calcification and ossification
The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
US09744218B2 Multi-chamber applicator for gelatin solution
Disclosed is a multi-chamber applicator comprising an aqueous gelatin solution and an aqueous cross-linking agent solution in separate chambers.
US09744211B2 Uses of BT lipopeptides as therapeutics for obesity and related diseases
The invention provides compositions and uses for treating or preventing obesity and related diseases in patients.
US09744202B2 Compositions and methods to reduce hangover and reduce blood alcohol levels after alcohol consumption
Compositions and methods for preventing and/or reducing hangover, when consumed before, after or during drinking alcohol. Compositions of the inventions include fructose powder, prickly pear extract, N-acetyl cysteine; kudzu; lemon balm; Vitamin C; nopal; white willow bark extract; milk thistle; Vitamin B1; Vitamin B6; lemon juice; acacia fiber; and other ingredients.
US09744201B2 Red ginseng saponin extract and method for preparing the same
Disclosed is a method for preparing a red ginseng saponin extract. In the method, saponin components and non-saponin components are extracted from red ginseng and the non-saponin components are selectively removed from the red ginseng extract to prepare a red ginseng extract containing large amounts of the saponin components. According to the method, saponin components are extracted from red ginseng in high yield and non-saponin components are efficiently removed from the extract. Also disclosed is a red ginseng saponin extract prepared by the method. The red ginseng saponin extract is free of precipitable substances and putrefactive substances, such as starch and free sugars, and contains high-purity saponin components at high concentrations. The red ginseng saponin extract is prevented from being discolored and precipitated even after long-term storage, achieving good storage stability and high marketability.
US09744199B2 Herpes simplex virus (HSV) with modified tropism, uses and process of preparation thereof
A modified Herpes Simplex Virus (HSV), which has a portion of gD (glycoprotein D) of the glycoproteic envelope deleted and a heterologous single chain antibody inserted in place of such deleted portion; the modified HSV is capable of infecting cells through receptor HER2/ErbB2 but not through receptors HVEM/HveA and nectin1/HveC; uses of the modified HSV and a process of the preparation thereof are also disclosed.
US09744197B2 Process and composition for manufacture of a microbial-based product
Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products are disclosed. These microbial-based products are useful for inhibiting pathogenic growth and as a food additive. A preferred microorganism is a lactic acid producing bacteria. In one embodiment, the process comprises inoculating a lactobacillus fermentation medium with lactic acid producing bacterial cells, harvesting the lactic acid producing bacterial cells at mid to late log phase, concentrating the lactic acid producing bacterial cells, and preserving the lactic acid producing bacterial cells at a concentration of at least 5×109 cfu/ml.
US09744194B2 Methods of treating ischemic spasticity
The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
US09744192B2 Methods of treating chronic rhinosinusitis
The present invention provides methods of treating chronic rhinosinusitis that comprise administering a formulation of boric acid to the nasal and paranasal cavities of a patient in need. The present invention also provides for the use of a formulation comprising boric acid for the treatment of chronic rhinosinusitis.
US09744188B2 Methods of promoting neuronal outgrowth by gypican 2 that binds to receptor protein tyrosine phosphatase sigma
Disclosed herein are methods of inducing neuronal outgrowth of a neuron. The methods comprise contacting the neuron with an agent that binds receptor protein tyrosine phosphatase δ (RPTPδ), to thereby induce neuronal outgrowth of the neuron. The agent may induces clustering of RPTPδ and/or inhibit binding of chondroitin sulfate proteoglycan (CSPG) to RPTPδ. Examples of suitable agents are heparan sulfate proteoglycan, heparan sulfate, heparan sulfate oligosaccharides, or heparin oligosaccharides. Additional agents are also disclosed. The neuron can be a CNS neuron or peripheral neuron. Also disclosed herein are methods of treating neuronal injury in a subject comprising, administering to the subject an agent that binds RPTPδ. Administration may be to a site of neuronal injury, to thereby induce neuronal outgrowth at the site of neuronal injury.
US09744184B2 Trehalulose-containing composition, its preparation and use
The present invention relates to a trehalulose-containing composition, its preparation and use.
US09744182B2 Dietary supplement containing phospholipid-DHA derived from eggs
Described herein are manufactured dietary supplements that contain a phospholipid extract, folic acid, vitamin D, vitamin B6, vitamin B12, Vitamin E, Vitamin C, iodine, iron, and magnesium.Described herein are manufactured dietary supplements that contain a phospholipid extract that contain phospholipid-DHA.
US09744178B2 Respirable agglomerates of porous carrier particles and micronized drug
Embodiments of the present invention provide a dry powder composition comprising porous carrier particles associated with one, two, three or more micronized drugs or APIs wherein an ordered mixture between the micronized drug or drugs and the carrier particle results, such that the micronized drug or drugs adhere strongly to the carrier particles forming a stable ordered mixture of respirable agglomerates. Embodiments of the present invention further comprise a spray-drying process to create the respirable agglomerates. Embodiments of the present invention further relate to the use of the dry powder formulation comprising respirable agglomerates for the treatment of a patient having a disease or condition which is treatable thereby.
US09744171B2 Positive allosteric modulators for melanocortin receptors
Positive allosteric modulators of melanocortin receptors, especially allosteric potentiators of the receptors MC3R and MC4R are described herein. Also provided are pharmaceutical compositions containing the positive allosteric modulators and methods of treating obesity or an obesity-related disorder such as type 2 diabetes, comprising administering an effective amount of the positive allosteric modulator.
US09744170B2 Solid antiviral dosage forms
The present disclosure relates to solid dosage forms comprising antiviral compounds and methods of using such dosage forms to treat antiviral infection.
US09744165B2 Method for treating hypertension
Dextromethorphan is used to lower blood pressure in a subject suffering from hypertension, alone or in combination with another anti-hypertensive agent. In particular, dextromethorphan acts synergistically with a calcium channel blocker, such as amlodipine, to result in a major improvement in the treatment of hypertension, with no or little adverse effects.
US09744163B2 Compositions of a polyorthoester and an aprotic solvent
Delivery systems and compositions comprised of a biodegradable polyorthoester polymer, an aprotic solvent, and a drug are described. The solvent is selected to modulate release of drug from the composition, where, in some embodiments, the solvent is rapidly released after administration and provides a corresponding rapid rate of drug release. Alternatively, in other embodiments, the solvent is slowly released from the composition after its administration, and provides a correspondingly slow rate of drug release.
US09744156B2 Methods and compositions for enhanced transungual delivery of AR-12
Methods and compositions for enhancing transungual delivery of AR-12 comprising administering AR-12 and permeation enhancers are provided.
US09744155B2 IPA as a therapeutic agent, as a protective agent, and as a biomarker of disease risk
Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
US09744154B2 Polymorphic forms of ST-246 and methods of preparation
Polymorph forms of 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide are disclosed as well as their methods of synthesis and pharmaceutical compositions.
US09744153B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors
A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.
US09744152B2 Vitamins C and K for treating polycystic diseases
Provided herein is a pharmaceutical composition comprising vitamin C and chromium-free vitamin K, and optionally one or more pharmaceutically acceptable excipient(s). Also provided herein is a chromium-free pharmaceutical composition comprising vitamin C and vitamin K, and optionally one or more pharmaceutically acceptable excipient(s). Further provided herein is a method of treating, preventing, or managing an NFκB-mediated condition, disorder, or disease, comprising administering to the subject a therapeutically effective amount of vitamin C and chromium-free vitamin K. Provided herein are methods for treating, preventing, or ameliorating one or more symptoms of a polycystic disease in a subject, comprising administering to the subject a therapeutically effective amount of vitamins C and K.
US09744149B2 Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
This invention relates to the treatment of breast cancer in a subject, for example a female subject. Including methods of: treating metastatic breast cancer; refractory breast cancer; AR-positive breast cancer; AR-positive refractory breast cancer; AR-positive metastatic breast cancer; AR-positive and ER-positive breast cancer; triple negative breast cancer; advanced breast cancer; breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments; metastasis in a subject suffering from breast cancer; comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound.
US09744148B2 Kallikrein 7 inhibitors
The present invention relates to methods for inhibiting the activity of human kallikrein 7 (KLK7) (also known as serine protease stratum corneum chymotryptic enzyme, SCCE). The invention further relates to the use of KLK7 inhibitors of Formula I for the treatment and prevention of diseases, more specifically for the treatment and prevention of skin diseases. The invention also provides new compounds demonstrated to be inhibitors of KLK7.
US09744147B2 Isoprenyl compounds and methods thereof
Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical, cosmetic, cosmeceutical and topical compositions comprising these isoprenyl compounds. Anti-inflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with inflammation. Proinflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with suppression of inflammatory responses. Thus, the present invention also provides methods useful in the treatment or prevention of diseases or conditions associated with inflammation as well as methods useful in the treatment or prevention of diseases or conditions associated with suppression of inflammatory responses.
US09744146B2 Method for alleviating disturbance of bile acid metabolism, amino acid metabolism, and/or gut microbiota metabolism
A method for alleviating at least one of the disturbance of bile acid metabolism, the disturbance of amino acid metabolism, and the disturbance of gut microbiota metabolism in a subject, comprising administering to the subject a composition or a health food comprising an active component selected from the group consisting of gallic acid, a pharmaceutically acceptable salt of gallic acid, a pharmaceutically acceptable ester of gallic acid, and combinations thereof.
US09744141B2 Multifunctional nanoparticle designs and applications
Methods, structures, devices and systems are disclosed for fabricating and implementing nanoparticles with hollow core and sealable holes. In one aspect, a nanoparticle device can includes a shell structure including at least two layers including an internal layer and an external layer, the internal layer structured to enclose a hollow interior region and include one or more holes penetrating the internal layer, the external layer is of a porous material and formed around the internal layer and sealing the one or more holes, and a substance contained within the hollow interior region, the substance incapable of passing through the external layer.
US09744137B2 Topiramate compositions and methods of enhancing its bioavailability
The present invention is directed to pharmaceutical compositions that allow for once-daily or alternate day dosage forms of topiramate. The proposed delayed/extended release single dosage form is equivalent to the immediate-release multiple dose daily regimen, and upon administration, provides steady state blood levels of topiramate. Formulations with increased bioavailability and improved pharmacokinetics are disclosed. A once-a-day administration of topiramate is advantageous over the multiple dose regimen both in terms of patient compliance and reduced adverse events, thus providing better treatment of the conditions for which the topiramate is indicated.
US09744133B2 Enhanced stability of novel liquid compositions
The present invention relates to compositions of pharmaceutical agents in combination with additional pharmaceutical agents in a mixture of polyethylene glycol, polyvinylpyrrolidone, and propylene glycol and a process of making the compositions.
US09744130B2 Cationic dry powders
The invention relates to respirable dry particles that contain one or more divalent metal cations, such as magnesium, in an amount of less than 3% by weight, and to dry powders that contain the respirable particles. The dry particles can further contain an active agent, or can be used as carrier particles to deliver an active agent.
US09744128B2 Method for manufacturing medicated chewing gum without cooling
An improved method for manufacture of chewing gums containing active ingredient(s) that preserves the efficacy of the active ingredient(s) by avoiding exposure to high heat and extreme cold during milling that can otherwise degrade the active's efficacy. A chewing gum base is used, along with one or more therapeutically-active ingredients, one or more sweeteners (alcohol-based and/or natural), and one or more flavorings and optional flavor modifiers. The method generally comprises heating the gum base in ovens to melt the gum base. Separately, the active ingredient(s), sweeteners and flavorings are combined in a mixer. The melted gum base is added to the mixer and cools to produce a particulate mixture. As mixing continues the mass cools to room temperature and forms granular pieces. The granular pieces are ground into a powder at room temperature, mixed at room temperature with tableting excipients, and tableted. Several variations on the foregoing are also described.
US09744125B2 Use of a virucidal preparation on an area of the face for prevention of transmission or contraction of viral illnesses, or to shorten the duration of, or lessen the severity of viral illnesses
A method of reducing or inhibiting the contraction or communication of viral illnesses is proposed. Application of a virucidal preparation containing one or more organic acids (e.g. malic acid) with or without a surfactant (e.g. sodium C14-C16 olefin sulfonate) in a carrier agent (e.g. petrolatum) to the face of well individuals will reduce the chance that they contract illness with viral illnesses such as viral upper respiratory illnesses, influenza, viral gastroenteritis, viral rhinosinusitis, viral cold sores, and viral conjunctivitis. Application of said ointment to the nares of individuals with a VURI will reduce the chance they transmit the illness by reducing self-contamination of their hands when touching their nose. In addition, individuals suffering from a cold or influenza may reduce the duration or severity of illness by application of the nasal antiviral ointment. The ointment is most effective when applied with a clean applicator two or three times daily.
US09744124B2 Flowable composition that hardens on delivery to a target tissue site beneath the skin
Flowable compositions and methods are provided for delivering a therapeutic agent at or near a target tissue site beneath the skin of a patient, the flowable composition comprising (i) a solvent and (ii) an effective amount of the therapeutic agent, the flowable composition being capable of hardening to form a drug depot at a physiological temperature or as solvent contacts bodily fluid at or near the target tissue site, wherein the drug depot is capable of releasing the therapeutic agent over a period of at least one day and the target tissue site comprises at least one muscle, ligament, tendon, cartilage, spinal disc, spinal foraminal space near the spinal nerve root, facet or synovial joint, or spinal canal. In some embodiments, an implantable drug depot for delivering a therapeutic agent is provided, the implantable drug depot comprising (i) a chamber; and (ii) a flowable composition comprising an effective amount of a therapeutic agent disposed within the chamber of the drug depot, the flowable composition capable of hardening when the drug depot is delivered at or near the target tissue site.
US09744122B2 Topical formulation for pain relief
Described herein are topical pain compositions comprising between 15 and 90% mannitol, for use in the treatment of pain, itch and other cutaneous nerve conditions. The resulting compositions may be in the form of creams, gels, lotions, ointments, foams, suppositories, and sprays.
US09744114B2 Modified starches for use in personal care applications
The present invention details the use of starch silicate and starch siliconates in personal care formulations to enhance or provide aesthetic properties to skin care products. These properties can range from smoothness and silky feel to non-greasy and non-oily. These starch derivatives provide an alternative to organically modified starches which can be expensive to prepare and require the addition of inorganic salts to functionalize the reagents.
US09744110B2 Method of treating conditions of the eyelid
A method for tightening the fat septa of the hypodermis of the eyelids by administering an aqueous solution of citric acid resulting in the reduction of skin tenting, skin sag, lid laxity and skin overhang of the upper and lower eye lids.
US09744109B2 Eutectic mixtures in personal care compositions
The invention relates to active eutectic mixtures of butyl methoxydibenzoylmethane, isopropyl myristate and optionally 12-hydroxystearic acid, personal care products comprising such active eutectic mixtures, a method for preparing such personal care compositions and a method of applying to human skin such personal care compositions.
US09744108B2 Methods and compositions for preventing and treating tooth erosion
Methods and compositions are provided for reducing, treating or preventing dental erosion in a patient in need of such treatment, the methods and compositions comprising administering a therapeutically effective amount of an alkalinizing agent and a re-mineralizing agent to the teeth. Dental erosion is a significant oral health problem that affects millions of individuals around the world. Erosive tooth wear can cause significant tooth damage compromising the esthetics and function of teeth, requiring extensive dental treatment.
US09744105B2 Topical glycopyrrolate formulations
Individually packaged topical formulations comprising about 0.25 to about 6% w/w of glycopyrrolate for the treatment of hyperhidrosis, wherein said wipe is contained within a pouch resistant to leakage. The formulations may further comprise ethanol, a buffering agent and water. In addition, the formulations may further comprise a polymer system comprising a hydrophobic polymer in combination with a hydrophilic polymer.
US09744103B1 Infant teething apparatus
A generally triangular teething apparatus incorporating slots is provided for receiving and securing a cleaning cloth. The teething apparatus includes a body portion having a teething portion, a cross-bar and a rear bar. A first slot is defined between the teething portion and the cross-bar while a second slot is defined between the cross-bar and the rear bar. The rear bar includes a top flexible bar or flap and a bottom flexible bar or flat that define a third slot therebetween and oriented transverse to the second slot. The teething portion is provided with a series of bumps for therapeutic purposes. There is also method of attaching a cleaning cloth to the teething apparatus by threading the cleaning cloth through the slots.
US09744092B2 Limb rehabilitation and training system
A limb rehabilitation and training system includes a horizontal position adjuster movably mounted at a bottom side of a base, an expansion rotary member mounted at the horizontal position adjuster, a shoulder joint traction mechanism linked to the expansion rotary member through a first arm segment robotic arm and a height adjuster, and an upper-limb rehabilitation device linked to the shoulder joint traction mechanism. The upper-limb rehabilitation device is able to rapidly be adjusted to fit the left arm or right arm through the horizontal position adjuster, the expansion rotary member, the first arm segment robotic arm and a shoulder positioning-lifting rotary member and. Further, by means of the shoulder joint traction mechanism, the user's stiffened shoulder joint can be timely moved for a separation distance, achieving the function of loosening the joint and facilitating performance of successive rehabilitation treatment or training.
US09744089B2 Surgery table apparatus
A surgery table utilizing first and second sections which are hingedly attached to one another. First and second sections are also connected to supports apart from the hinged portion. An elevator moves one of the sections upwardly and downwardly at the support. The resultant position of the frame formed by the first and second sections may take the configuration of a flat surface or an upwardly or downwardly oriented “V”.
US09744079B2 Reduced-pressure, linear-wound treatment systems
A system for treating a linear wound on a patient has a closing dressing bolster for placing on the patient's epidermis over the linear wound, a sealing subsystem for providing a seal over the closing dressing bolster and the patient, and a reduced-pressure subsystem for delivering reduced pressure to the sealing subsystem. The sealing subsystem and reduced pressure subsystem are operable to deliver reduced pressure to the closing dressing bolster. The closing dressing bolster is operable under reduced pressure to develop a inward closing. The closing dressing bolster may include one or more closing members on each side of a center wound area to create the inward closing when under reduced pressure. A compressive force may also be developed. Other systems and methods are presented.
US09744078B2 Sound absorbing device of the type adapted to cover the ears of a user
A sound absorbing device of the type adapted to cover the ears of a user and comprising a sound absorbing material, wherein the sound absorbing material comprises of a thixotropic material.
US09744077B2 Methods of laser modification on intraocular lens
A method of modifying a refractive profile of an eye having an intraocular device implanted therein, wherein the method includes determining a corrected refractive profile for the eye based on an initial refractive profile, identifying one or more locations within the intraocular device based on the corrected refractive profile, and directing a pulsed laser beam at the locations to produce the corrected refractive profile. A system of modifying an intraocular device located within an eye, wherein the system includes a laser assembly and a controller coupled thereto. The laser assembly outputs a pulsed laser beam having a pulse width between 300 picoseconds and 10 femtoseconds. The controller directs the laser assembly to output the pulsed laser beam into the intraocular device. One or more slip zones are formed within the intraocular device in response thereto, and the slip zones are configured to modify a refractive profile of the intraocular device.
US09744075B2 Instrument and method for creating a controlled capsulorhexis for cataract surgery
An instrument and method for creating a precise capsulorhexis as a step in cataract surgery is described. The instrument has a curvilinear cutting band attached to a longitudinal support component and cutting band extending on two sides of the support. In an embodiment, the cutting band has a sinusoidal shape. The support is coupled to a supporting structure, and then to a handle, the supporting structure is shaped to permit it to pass through an incision at a side of a cornea of the eye while positioning the cutting band on an anterior surface of an anterior capsule of a lens of the eye. In an embodiment of the method, the incision in the anterior capsule is formed by pressing the cutting band into the anterior capsule, and capsulorhexis is extended by tearing away the two tabs formed and defined by curvature of the cutting band.