Document Document Title
US09598515B2 Processes for preparing solid metallocene-based catalyst systems
Methods for preparing metallocene-based catalyst systems containing an activator-support are disclosed. These methods can include contacting a solid metallocene compound, an activator-support, and an organoaluminum compound, resulting in catalyst systems with increased catalytic activity as compared to catalyst systems utilizing a solution of the metallocene compound.
US09598510B2 Telechelic polyolefin and preparation thereof
Telechelic polyolefin of formula(I) and its derivatives: CH2═CH—(CH2)p-A-Z  (I) wherein: A represents a (co)polymer comprising at least 95 mol % of (CH2—CH2) units; Z is selected from the group comprising halogens, thiols and their derivatives, azides, amines, alcohols, the carboxylic acid function, isocyanates, silanes, phosphorous derivatives, dithioesters, dithiocarbamates, dithiocarbonates, trithiocarbonates, alkoxyamines, the vinyl function, dienes, and the group -A-(CH2)p—CH═CH2; p is a whole number between 1 and 20, most advantageously between 6 and 9.
US09598501B2 Antibody-immobilized carrier, method of producing antibody-immobilized carrier, and use of said antibody-immobilized carrier
The present invention provides an antibody-immobilized carrier that can be used in antibody screening, a method of producing the antibody-immobilized carrier, and use of the antibody-immobilized carrier. Efficient antibody screening can be carried out particularly by an antibody-immobilized carrier including two or more antibody immobilized regions onto each of which a heavy-chain low-molecular-weight antibody and a light-chain low-molecular-weight antibody are separately immobilized, the two or more antibody immobilized regions each being included in an independent manner, the heavy-chain low-molecular-weight antibody including a heavy-chain variable region, the light-chain low-molecular-weight antibody including a light-chain variable region, the heavy-chain low-molecular-weight antibody and the light-chain low-molecular-weight antibody each being derived from an antibody recognizing a different antigen.
US09598499B2 Antigen binding formats for use in therapeutic treatments or diagnostic assays
The present invention relates to antigen binding formats for use in therapeutic treatments or diagnostic assays. The present invention relates to an antigen-binding format consisting of: —a first fusion protein wherein the CH1 constant domain of an antibody is fused i) by its N-terminal end to the C-terminal end of a variable domain of an antibody and ii) by its C-terminal end to the N-terminal end of a variable domain of an antibody and, —a second fusion protein wherein the CL constant domain of an antibody is fused by its N-terminal end to the C-terminal end of a variable domain of an antibody.
US09598496B2 Antibody capable of specifically recognizing transferrin receptor
An object of present invention is to provide a complete human anti-human TfR antibody, which specifically recognizes human TfR, inhibits the survival or growth of cancer cells that highly express TfR, and has no immunogenicity to humans. The present invention provides an antibody which specifically reacts with human TfR, wherein the antibody comprises any one of the amino acid sequences shown in SEQ ID NOS: 1-3, 7-9, 13-15, 19-21, 25-27, 31-33, 37-39, 43-45, 49-51, 55-57, 61-63, 67-69, 73-75, 79-81, 85-87, 91-93, 97-99, 103-105, 109-111, and 115-117, as each of a heavy chain first complementarity determining region (VH CDR1), a heavy chain second complementarity determining region (VH CDR2), and a heavy chain third complementarity determining region (VH CDR3).
US09598494B2 Anti-CD40 antibody mutants
A mutant of a potentially therapeutic anti-CD40 antibody is provided which mutant has reduced ADCC and CDC activities designed to be optimized as a pharmaceutical agent. A mutant of an agonistic anti-CD40 antibody, comprising mutation and/or substitution of at least one amino acid in the constant region to reduce the ADCC and/or CDC activities therein, and a mutant of an antagonistic anti-CD40 antibody, comprising at least one mutation or substitution in the constant region to reduce the ADCC and/or CDC activities therein, both mutants having at least a hinge region derived from a human IgG2.
US09598492B2 Human monoclonal antibodies specific for CD22
Disclosed herein are isolated human monoclonal antibodies that specifically bind human CD22 with a dissociation constant (Kd) of 25 nM or less. Nucleic acids encoding these antibodies, expression vectors including these nucleic acid molecules, and isolated host cells that express the nucleic acid molecules are also disclosed. The antibodies can be used to detect human CD22 in a sample. In some cases, CD22 is soluble CD22. Methods of diagnosing a B-cell malignancy, or confirming a B-cell malignancy diagnosis, are disclosed herein that utilize these antibodies. Methods of treating a subject with a B-cell malignancy are also disclosed.
US09598491B2 Methods for the treatment of infections and tumors
PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-1 antagonists. In addition, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-1 antagonist. Methods are also disclosed for determining the efficacy of a PD-1 antagonist in a subject administered the PD-1 antagonist. In some embodiments, these methods include measuring proliferation of memory B cells in a sample from a subject administered the PD-1 antagonist.
US09598489B2 Human alpha-folate receptor chimeric antigen receptor
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having alpha-folate receptor (FR-alpha) binding domain and CD27 costimulatory domain to treat ovarian cancer. In an embodiment, the FR-alpha binding domain is fully human, thereby preventing a host immune response.
US09598483B2 Monoclonal antibody binding specifically to DLL4 and use thereof
The present invention relates to a novel monoclonal antibody that binds specifically to delta-like ligand (DLL4), and more particularly to a monoclonal antibody that binds specifically to human delta-like ligand 4 to effectively inhibit the interaction between delta-like ligand 4 and Notch receptor, a polynucleotide encoding the monoclonal antibody, an expression vector comprising the polynucleotide, a transformant comprising the expression vector, a method for preparing the monoclonal antibody, a pharmaceutical composition for preventing or treating cancer comprising the monoclonal antibody, a composition for diagnosing cancer comprising the monoclonal antibody, a method for diagnosing cancer using the monoclonal antibody, and a pharmaceutical composition for preventing or treating autoimmune disease comprising the monoclonal antibody.
US09598480B2 Recombinant NEL-like (NELL) protein production
The present invention provides a method and system for producing a NELL protein. The method and system comprise a CELL encoding a NELL protein or peptide and a non-insect secretory signal peptide.
US09598479B2 Nanoparticle-peptide compositions
The present invention provides nanoparticles and compositions comprising such nanoparticles, as well as methods for intracellular delivery of peptides, and methods of producing nanoparticles and related products. The nanoparticles comprise a core comprising a metal and/or a semiconductor atom; and a corona comprising a plurality of ligands covalently linked to the core, wherein at least a first ligand of said plurality comprises a carbohydrate moiety that is covalently linked to the core via a first linker, and wherein at least a second ligand of said plurality comprises a peptide of choice that is covalently linked to the core via a second linker. The second linker comprises a peptide portion and a non-peptide portion, wherein said peptide portion of said second linker comprises the sequence X1X2Z1, wherein: X1 is an amino acid selected from A and G; X2 is an amino acid selected from A and G; and Z1 is an amino acid selected from Y and F.
US09598473B2 Trichome-specific transcription factor modulating terpene biosynthesis
The present invention relates to identification and isolation of zinc finger transcription factor in tomato that specifically expresses in glandular trichomes of Solanum lycopersicum cultivar Moneymaker and binds to the promoters of the genes encoding Terpene Synthase 5 (also known as Monoterpene Synthase 1) and Terpene Synthase 11 (also known as Sesquiterpene Synthase 1). The invention provides the isolated, recombinant or synthetic polynucleotides encoding the polypeptide sequences of SEQ ID NO:2 and variants and fragments thereof. The invention also provides constructs, vectors, host cells and plants genetically modified to contain the polynucleotides of the invention. The methods for producing plants with altered levels of terpenes, including transformed and mutant plants, are also provided.
US09598472B2 Isolated polypeptide of the toxin A and toxin B proteins of C. difficile and uses thereof
This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C. difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO: 2 and SEQ ID NO: 4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C. difficile toxin A and/or toxin B.
US09598467B2 Recombinant HCV E2 glycoprotein
The invention provides modified hepatitis C virus (HCV) E2 glycoproteins comprising the HCV-E2 receptor-binding domain (RBD) including the HVR1, HVR2 and igVR variable regions wherein in at least one of said variable regions at least a part of the variable region is replaced with a flexible linker sequence. The invention also provides vaccine compositions comprising the modified glycoproteins as well as methods of use thereof.
US09598464B2 Biologically active peptides
The invention provides a method of making a peptide or peptide derivative comprising the amino acid sequence comprising imfwydcye or a variant amino acid sequence comprising one, two, three, four, five or six amino acid substitutions in imfwydcye.
US09598461B2 Method of purifying therapeutic proteins
The present invention relates generally to a method of reducing the level of at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) in a solution comprising at least one protein selected from the group consisting of fibrinogen, Factor VIII and von Willebrand factor (VWF), the method comprising: (i) passing a feedstock comprising at least one protein selected from the group consisting of fibrinogen, Factor VIII and VWF through a hydrophobic charge-induction chromatographic resin under conditions selected such that at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) present in the feedstock is bound to the resin; and (ii) recovering a solution comprising the at least one protein selected from the group consisting of fibrinogen, Factor VIII and VWF which passes through the resin, wherein the concentration of the at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) in the solution is reduced by at least 50% compared to the feedstock. Also provided are solutions and pharmaceutical formulations comprising the fibrinogen and/or Factor VIII and/or VWF recovered by such methods, and uses thereof.
US09598456B2 Modified cytosine polynucleotide oligomers and methods
Disclosed are modified cytosine bases that provide enhanced base-pairing affinity for guanine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified cytosine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection.
US09598451B2 Bis-organometallic 2-amino-3-hydroxy-2-methylpropanenitrile derivatives for use as anthelmintics
The invention comprises a compound characterized by a general formula (1), wherein X is a group described by a general formula —Kp—Fl—Kq—, wherein Fl is —C(═O)—, —C(═S)—, with l being 0 or 1, Kp is a Cp-alkyl with p being 0, 1, 2, 3 or 4, Kq is a Cq-alkyl with q being 0, 1, 2, 3 or 4, and wherein Z is a group described by a general formula —Kr—Fi—Kt—, wherein Fi —O—, —S—, —O—C(═O)—, —O—C(═S)—, —S—C(═O)— or —NH—(C═O)— with i being 0 or 1, Kr is a Cr-alkyl with r being 0, 1, 2, 3 or 4, Kt is a Ct-alkyl with t being 0, 1, 2, 3 or 4, wherein each OM is an organometallic compound independently selected from each other from the group of an unsubstituted or substituted metal sandwich compound, an unsubstituted or substituted half metal sandwich compound or a metal carbonyl compound and their use.
US09598450B2 Emissive compounds for organic light-emitting diodes
Disclosed herein are compounds containing an optionally substituted (2-phenylpyridinato-N,C2′)(2,4-pentanedionato)Pt(II). Some embodiments provide a light-emitting device, having an anode layer, a cathode layer, and a light-emitting layer positioned between, and electrically connected to, the anode layer and the cathode layer, wherein the light-emitting layer contains a compound disclosed herein.
US09598449B2 Pyridine-oxyphenyl coordinated iridium (III) complexes and methods of making and using
Iridium (III) complexes are described together with methods to prepare and use such complexes. Also described are devices that utilize the iridium (III) complexes.
US09598443B2 Boron containing small molecules as antiprotozoal agents
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
US09598439B2 Purification of rapamycin derivatives using temperature induced phase separation
The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
US09598430B2 GLP-1 receptor modulators
Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “” represents either or both the R and S form of the compound): where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.
US09598428B2 Method for preparing a pyripyropene compound
The present invention relates to a method for preparing the pyripyropene compound of the formula (I) which method comprises the following steps: i) subjecting a pyripyropene compound of formula Pyripyropene A to an alkaline hydrolysis to yield a 1,7,11 -trideacetylpyripyropene A, ii) reacting 1,7,11-trideacetylpyripyropene A obtained in step i) with cyclopropane carbonyl chloride to yield a raw product containing the pyripyropene compound of formula (I); iii) subjecting the raw product of step ii) to crystallization to yield a crystalline pyripyropene compound of formula (I) and a mother liquor; and iv) recycling the mother liquor or a pyripyropene compound containing fraction thereof to the alkaline hydrolysis of step i).
US09598426B2 Organic compounds
Provided are PDE1 inhibitors of Formula I, processes for their production and their use as pharmaceuticals, and pharmaceutical compositions comprising them.
US09598424B2 Heteroarylamide inhibitors of TBK1
The present invention provides compounds of formula 1: which are useful as inhibitors of TBK-1, pharmaceutical compositionst thereof, methods for treatment of conditions associated with TBK1, processes for making the compounds and intermediates thereof.
US09598421B2 Imidazopyridazine compounds
The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R3, R6, R7, and b are as defined herein. The invention is also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, and methods of preparing the compounds.
US09598417B2 (Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use
The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired bleeding disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.
US09598416B2 Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer
This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-fJ[1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.
US09598415B2 Compounds as modulators of RORγ
The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
US09598414B2 Substituted benzo[5,6]azepino[3,2,1-hi]pyrido[4,3-b]indoles and substituted benzo[6,7][1,4]oxazepino[2,3,4-hi]pyrido[4,3-b]indoles for treating CNS disorders
The present invention discloses pyridoinolobenz[b,e]azepine derivatives of Formula 1, wherein X is —O—, —S—, —SO—, or —SO2—. Y is a single bond or a double bond. A and B are independently —(CH2)n—; and ‘n’ varies from 0 to 3. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
US09598413B2 Crystalline form of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-D]pyrrolo[2,3-B]pyridine-7-carboxamide for the treatment of myeloproliferative disorders
Crystalline form, Form T2H1.5-4, of N,Ndicyclopropyl-4-(1,5-dimethyl-1 Hpyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide, (Compound (I)) is provided. Also provided is a pharmaceutical composition and an oral dosage form comprising Form T2H1.5-4 of Compound (I) as well as a method of using the Form T2H1.5-4 of Compound (I) in the treatment of myeloproliferative disorders, which include polycythaemia vera, thrombocythaemia and primary myelofibrosis.
US09598408B2 Imidazo[4,5-C]quinolines as DNA-PK inhibitors
The invention relates to compounds of the formulae (I) and (II) in which R1, R2, R3, R4, R5, R8, X and m have the meaning indicated in the claims, and/or physiologically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. The compounds of the formula (I) can be used for the inhibition of serine/threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of cancer, tumours, metastases or angiogenesis disorders, in combination with radiotherapy and/or an anticancer agent. The invention furthermore relates to a process for the preparation of the compounds of the formula (I).
US09598407B2 Antibacterial piperidinyl substituted 3,4-dihydro-1H-[1,8]naphthyridinones
The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
US09598405B2 Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors
The invention provides certain thiazole-substituted aminopyridine compounds of the Formula (I) (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, Cy, and the subscript t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
US09598400B2 Substituted quinoline compounds and methods of use
The present invention provides novel substituted quinoline compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
US09598396B2 Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors
The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and Y have defined meanings.
US09598395B2 Premature-termination-codons readthrough compounds
Premature termination codons readthrough compounds, composition thereof, and methods of making and using the same are provided.
US09598394B2 Method of producing trioxane
Disclosed is a method of producing trioxane, including: (A) preparing trioxane from a high-concentration formaldehyde aqueous solution in the presence of an acid catalyst; (B) distilling a mixture including trioxane; (C) liquefying the distilled gas mixture; (D) mixing the liquefied liquid mixture with an extraction solvent and separating the mixture into an aqueous phase and a solvent phase; (E) distilling the solvent phase to give trioxane, and mixing the aqueous phase with the extraction solvent to give a mixture, which is then separated into an aqueous phase and a solvent phase; and (F) discharging the aqueous phase separated in (E) out of the system, and recirculating the solvent phase so as to be reused in (D) and (E).
US09598393B2 Structural variants of mycolactones for use in modulating inflammation, immunity and pain
The present invention is related to variants of mycolactones of formula (I), processes for the preparation thereof, pharmaceutical compositions thereof and their use in modulating inflammation, immunity and pain. Y—O—W (I), wherein Y and W are as defined in claim 1.
US09598390B2 Bicyclo[2.2.2]acid GPR120 modulators
The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
US09598388B2 Method for producing tetrahydrofuran
The present invention is concerned with a method for producing tetrahydrofuran including carrying out a dehydration cyclization reaction of 1,4-butanediol in the presence of an acid catalyst having a pKa value of not more than 4 within a reactor, wherein a raw material liquid containing 1,4-butanediol to be provided for the reaction contains from 0.01 to 0.35% by weight of 2-(4-hydroxybutoxy)-tetrahydrofuran and 1 ppm by weight or more and not more than 1,000 ppm by weight of at least one of an amine and an amide in terms of a concentration as converted into a nitrogen atom.
US09598387B2 Urea and amide derivatives of aminoalkylpiperazines and use thereof
Provided are compounds represented by the formula: with Y, Ri, and R2 being defined in the present disclosure; pharmaceutically acceptable salts thereof, deuterated forms thereof, isomers thereof, solvates thereof, and mixtures thereof. The compounds can be used for treating a patient suffering from a condition capable of treatment with a partial agonist or antagonist of the dopamine D2/D3 receptors and are especially useful for patients suffering from schizophrenia, depressions, neurodegenerative diseases such as Parkinson's, dyskinesias, substance abuse and relapse to substance abuse and addiction to substances such as cocaine, methamphetamine, nicotine and alcohol, glaucoma, cognitive disorders, restless leg syndrome, attention deficit hyperactivity disorders, hyperprolactinemia, autism, motor disturbances such as akathisia, rigor, dystonias as well as various disorders of the urinary tract and other neurologic disorders. Also provided are processes for the preparation of compounds of the present disclosure.
US09598379B2 Process for preparing melamine
Process for preparing melamine by converting urea in the presence of a solid catalyst in one reactor or in a plurality of reactors connected in series in the temperature range from 370° C. to 430° C., cooling and filtering the gas formed in the urea conversion, removing the melamine by desublimation and recycling a portion of the gas present after the melamine removal (“cycle gas”) into the reactor or the reactors, which comprises performing all of the above stages at a pressure in the range from 4 bar abs. to 10 bar abs.
US09598375B2 Substituted imidazole derivatives and methods of use thereof
The present invention provides imidazole derivatives of Formula (I) and pharmaceutically acceptable salts thereof. and their use in the treatment of diseases such as Alzheimer's Disease.
US09598370B2 Prolyl hydroxylase inhibitors and methods of use
The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
US09598369B2 Process for the preparation of amides from hindered anilines containing a perhaloalkyl group
The present invention provides a novel and improved process for the production of the production of hindered anilines containing perfluoroalky groups in good yield any by using close to stoichiometric amounts of acylating agent.
US09598367B2 Heterocyclic compounds as bromodomain inhibitors
The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
US09598365B2 Method for synthesizing cycloalkanyl[b]indoles, cycloalkanyl[b]benzofurans, cycloalkanyl[b]benzothiophenes, compounds and methods of use
A method of synthesizing cycloalkanyl[b]indoles, as well as related cycloalkanyl[b]benzofurans and cycloalkanyl[b]benzothiophenes is provided. The method is a single, multicomponent reaction that combines (1) an indole, benzofuran, or benzothiopene, (2) an aldehyde, ketone, or ketal, and (3) a diene in the presence of an acid, in particular a Ga(III) or In(III) salt. Compositions and methods of using these compounds to stimulate secretion and/or production of glucagon-like peptide-1 or inhibit the activity of Calcitonin Gene-Related Peptide receptor are also provided.
US09598362B2 Benzidine derivative, method for preparing same, and pharmaceutical composition containing benzidine derivative for treating liver disease caused by hepatitis C virus
The disclosed compounds have antiviral activity against C-type virus, an optical isomer thereof, a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating liver disease caused by hepatitis C virus. The benzidine derivative according to the present invention has excellent antiviral activity against hepatitis C virus and exhibits excellent medicinal activity in the living body, and thus the pharmaceutical composition containing the same as an active ingredient can be useful as a pharmaceutical composition for preventing or treating liver disease, such as acute hepatitis C, chronic hepatitis C, cirrhosis, or hepatocellular carcinoma, caused by C-type virus.
US09598359B2 Sulfonates from natural oil metathesis
Sulfonate compositions are disclosed. The compositions include alkanesulfonates, alkenesulfonates, sultones, and hydroxy-substituted alkanesulfonates. The sulfonates comprise a reaction product of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with a sulfonating or sulfitating agent. In one aspect, the sulfonate composition is a sulfo-estolide made by reacting a metathesis-derived C10-C17 monounsaturated acid or octadecene-1,18-dioic acid with a sulfonating agent, optionally in the presence of a saturated fatty acid. The sulfonates are valuable for a wide variety of end uses, including cleaners, fabric treatment, hair conditioning, personal care (liquid cleansing products, conditioning bars, oral care products), paint additives, antimicrobial compositions, agricultural uses, and oil field applications.
US09598357B1 Process for producing taurine from alkali taurinates
The present invention discloses a process and catalysts for producing taurine by catalytic ammonolysis of alkali ditaurinate, alkali tritaurinate, and their mixture. Useful catalysts are the ammonium and alkali salts of sulfate, bisulfate, sulfite, bisulfite, carbonate, bicarbonate, nitrate, phosphate, and organic carboxylic acids.
US09598354B2 Fumarate compounds, pharmaceutical compositions thereof, and methods of use
Fumarate compounds, pharmaceutical compositions comprising the fumarate compounds, and methods of using fumarate compounds and pharmaceutical compositions for treating neurodegenerative, inflammatory, and autoimmune disorders including multiple sclerosis, psoriasis, irritable bowel disorder, ulcerative colitis, arthritis, chronic obstructive pulmonary disease, asthma, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are disclosed.
US09598350B2 Process for preparing cinacalcet and pharmaceutically acceptable salts thereof
The present patent application relates to a process for preparing cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.
US09598349B2 Quinone based nitric oxide donating compounds for ophthalmic use
The present invention relates to nitric oxide donor compounds having a quinone based structure, to processes for their preparation and to their use in the treatment and/or prophylaxis of glaucoma and ocular hypertension.
US09598346B2 Enantioselective process for the preparation of enantiomers of sex pheromones
The invention disclosed herein relates to an enantioselective process for preparation of biologically active (R) and (S) enantiomers of sex pheromones of the long-tailed Mealybug with high enantiopurity having significant biological activity. Further, the invention provides absolute configuration of synthesized R and S enantiomers.(I)
US09598343B2 Methods for the valorization of carbohydrates
There are provided methods for the valorization of carbohydrates. The methods comprise reacting a fluid comprising at least one carbohydrate with at least one metal catalyst or at least one metal catalytic system in a fluidized bed reactor so as to obtain at least one organic acid or a derivative thereof.
US09598342B2 Production of acetic acid with enhanced catalyst stability
Processes for the production of acetic acid by carbonylation of methanol and reactive derivatives thereof in a liquid phase reaction medium, wherein the reaction medium comprises a finite amount of water, a homogeneous catalyst, an alkyl halide promoter, and a catalyst stabilizer/co-promoter comprising an imidazolium cation R1R2Im+ as an iodide salt, wherein R1 and R2 are each independently a substituted or unsubstituted alkyl or cycloalkyl, with the proviso that R1 and R2 are not the same.
US09598341B2 Process to prepare levulinic acid
The invention describes processes to prepare levulinic acid, formic acid and/or hydroxymethyl furfural from various biomass materials.
US09598338B2 Myricanol derivatives and uses thereof for treatment of neurodegenerative diseases
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated with abnormal accumulation of protein tau.
US09598337B2 Methods for recovering chlorinated hydrocarbons
Processes for isolating 1,1,1,2,3-pentachloropropane from a crude product stream containing the 1,1,1,2,3-pentachloropropane and ferric chloride. The processes may include deep distillation of the crude, treatment of the crude with a reagent that deactivates the ferric chloride followed by distillation on the deactivated crude stream, aqueous washing of the crude product stream to remove ferric chloride followed by distillation on the deactivated crude stream. Other embodiments simultaneously prepare 1,1,2,3-tetrachloroprene and 1,1,1,2,3-pentachloroprane.
US09598336B2 Catalytic hydrogenation of fluoroolefins, alpha-alumina supported palladium compositions and their use as hydrogenation catalysts
A hydrogenation process is disclosed. The process involves reacting a fluoroolefin with H2 in a reaction zone in the presence of a palladium catalyst to produce a hydrofluoroalkane product, wherein the palladium catalyst comprises palladium supported on a carrier wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the carrier. Also disclosed is a palladium catalyst composition consisting essentially of palladium supported on α-Al2O3 wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the α-Al2O3. Also disclosed is a hydrogenation process comprising reacting a fluoroolefin with H2 in a reaction zone in the presence of a palladium catalyst to produce a hydrofluoroalkane product, characterized by: the palladium catalyst consisting essentially of palladium supported on α-Al2O3 wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the α-Al2O3. Also disclosed is a hydrogenation process comprising (a) passing a mixture comprising fluoroolefin and H2 through a bed of palladium catalyst in a reaction zone wherein the palladium catalyst comprises palladium supported on a carrier; and (b) producing a hydrofluoroalkane product; characterized by: the palladium catalyst in the front of the bed having lower palladium concentration than the palladium catalyst in the back of the bed.
US09598331B2 Olefin conversion process
Processes for the production of high purity alpha olefins from a mixture of olefins are disclosed. The processes may include: contacting propylene and a hydrocarbon mixture comprising a mixture of olefins having a carbon number n with a first metathesis catalyst to form a metathesis product comprising a beta-olefin having a carbon number n+1, an alpha-olefin having a carbon number n−1, as well as any unreacted propylene and olefins having a carbon number n. The metathesis product may be fractionated to recover a fraction comprising the beta-olefin having a carbon number n+1. Ethylene and the fraction comprising the beta-olefin having a carbon number n+1 may then be contacted with a second metathesis catalyst to form a second metathesis product comprising an alpha-olefin having a carbon number n and propylene, which may be fractionated to form a propylene fraction and a fraction comprising the alpha olefin having a carbon number n.
US09598329B2 Ethylene oligomerization process
An ethylene oligomerization system is useful for creating 1-butene from ethylene in the presence of an ethylene oligomerization catalyst. The ethylene oligomerization system includes an internal baffle single pass reactor, a separation system and an exterior motion driver. The exterior motion driver is operable to induce unsteadiness in the flow of the process fluid contained in the internal baffle single pass reactor by transferring motion into the process fluid. An ethylene oligomerization process is useful for creating a refined 1-butene product from ethylene using the ethylene oligomerization system.
US09598326B2 Process for the conversion of oxygenates to olefins
The present invention relates to a process for the conversion of oxygenates to olefins comprising (i) providing a gas stream comprising one or more oxygenates; and (ii) contacting the gas stream with a catalyst; wherein the catalyst comprises a zeolitic material having an MFI, MEL, and/or MWW-type framework structure comprising YO2 and X2O3, wherein Y is a tetravalent element, and X is a trivalent element, said zeolitic material being obtainable and/or obtained according to a method comprising (1) preparing a mixture comprising one or more sources for YO2, one or more sources for X2O3, and one or more solvents; and (2) crystallizing the mixture obtained in step (1) to obtain a zeolitic material having an MFI, MEL and/or MWW-type framework structure; wherein the mixture crystallized in step (2) contains 3 wt.-% or less of the one or more elements M based on 100 wt.-% of YO2, wherein M stands for sodium.
US09598325B2 Method for stabilizing a composition containing at least one product of internal dehydration of a hydrogenated sugar, resulting composition and uses thereof
A method for improving the stability of compositions of a product for internal dehydration of a hydrogenated sugar, in particular an isosorbide composition, the method involving the use of monoethanolamine, diethanolamine, triethanolamine and the mixtures thereof as a stabilization agent. The resulting compositions and their various uses thereof are also described.
US09598321B2 Melt infiltration wick attachment
A method and apparatus for providing molten metal infiltration into a component is provided.
US09598318B1 Chromia refractory brick with carbon treatment
The disclosure provides a refractory brick system comprising a chromia refractory brick for operation in the slagging environment of an air-cooled gasifier. The chromia refractory brick comprises a ceramically-bonded porous chromia refractory having a porosity greater than 9% and having carbon deposits residing within the pores. The brick may be further comprised of Al2O3. The air-cooled gasifier generates a liquefied slag in contact with the refractory brick and generally operates at temperatures between 1250° C. and 1575° C. and pressures between 300 psi to 1000 psi, with oxygen partial pressures generally between 10−4 and 10−10 atm. The refractory brick performs without substantial chromium carbide or chromium metal formation in the low oxygen partial pressure environment. The inclusion of carbon without chromium carbide formation provides for significant mitigation of slag penetration and significantly reduced refractory wear.
US09598316B2 Solution comprising organofunctional alkali siliconates, silicates and method of production thereof
The invention relates to a method for producing a solution comprising organofunctional siliconates, silicates and, optionally, the cocondensation products thereof, and to the solutions and an installation for the production thereof.
US09598305B2 Synthetic quartz glass substrate and making method
A synthetic quartz glass substrate has a surface of 6 inch squares including a central surface area of 132 mm squares. The central surface area of 132 mm squares has a flatness of up to 50 nm. A frame region obtained by subtracting the central surface area of 132 mm squares from the central surface area of 148 mm squares has a flatness of up to 150 nm.
US09598296B2 Decanted bio-balanced reactor and method
A wastewater treatment system is provided having a reactor, first and second bio media and an aeration system. The first bio medium is located proximate an inlet end of the reactor and extends vertically between a top water level and the reactor's floor. The second bio medium is located proximate an outlet end of the reactor and extends vertically between a bottom water level and the reactor's floor. The media are adapted for retaining solids within the reactor as clarified water is withdrawn after treatment. The first bio media is further adapted to act as a baffle thereby causing wastewater to flow generally uniformly into a primary reactor zone. The aeration system includes a plurality of diffusers, some of which may be located adjacent or underneath the bio media and are adapted for promoting the shaking the bio media when activated in order dislodge excessive biomass therefrom.
US09598295B2 Micronized CaCO3 slurry injection system for the remineralization of desalinated and fresh water
The present invention concerns a process for treating water and the use of calcium carbonate in such a process. In particular, the present invention is directed to a process for remineralization of water comprising the steps of (a) providing feed water having a concentration of carbon dioxide of at least 20 mg/l, preferably in a range of 25 to 100 mg/l, and more preferably in a range of 30 to 60 mg/l, (b) providing an aqueous slurry comprising micronized calcium carbonate, and (c) combining the feed water of step (a) and the aqueous slurry of step (b) in order to obtain remineralized water.
US09598293B2 Feather oil absorbent boom structure
A feather oil absorbent boom structure comprising an inner core and an outer ring winding outside the inner core; the inner core is a cloth bag, and the cloth bag is filled with feather oil absorbent material; the cloth bag is made of spunbonded-melt blown-spunbonded polyporpylene non-woven cloth; the outer ring is a plate-shaped oil absorbent felt formed through thermal fusion of feathers and bicomponent fibers of polypropylene/polyethylene having a low melting point; the weight ratio of the feathers to the bicomponent fibers is 70-85:15-30. The feather oil absorbent boom is capable of providing reliable buoyancy, and slowing down the reduction of the strength of the inner core. Further disclosed is a preparation method for the feather oil absorbent boom structure.
US09598290B2 Process for producing ammonia and urea
Disclosed is a process for the production of ammonia comprising a step wherein synthesis gas is formed by catalytic partial oxidation. Also disclosed is a process of producing urea, wherein ammonia is formed in a process involving a step of catalytic partial oxidation, and carbon dioxide formed in the same process is reacted with said ammonia so as to form urea.
US09598285B2 Apparatus for producing aligned carbon nanotube aggregates
An apparatus of the present invention for producing aligned carbon nanotube aggregates is an apparatus for producing aligned carbon nanotube aggregates, the apparatus being configured to grow the aligned carbon nanotube aggregate by: causing a catalyst formed on a surface of a substrate to be surrounded by a reducing gas environment constituted by a reducing gas; heating at least either the catalyst or the reducing gas; causing the catalyst to be surrounded by a raw material gas environment constituted by a raw material gas; and heating at least either the catalyst or the raw material gas, at least either an apparatus component exposed to the reducing gas or an apparatus component exposed to the raw material gas being made from a heat-resistant alloy, and having a surface plated with molten aluminum.
US09598283B1 Synthesis method for controlling antimony selenide nanostructure shapes
Methods are provided for controlling the shape of antimony selenide (Sb2Se3) synthesized nanostructures. The method dissolves an antimony (III) salt in a first amount of carboxylic acid, forming an antimony precursor. In one aspect, antimony (III) chloride is dissolved in oleic acid. Separately, selenourea is dissolved in oleylamine, forming a selenium precursor. The antimony precursor is combined with the selenium precursor to form a first solution and cause a reaction. The reaction is quenched with a solvent having a low boiling point. In response to quenching the reaction in the first solution, antimony selenide nanorods are formed, having a length in the range of 150-200 nanometers (nm) and a diameter in the range of 20 to 30 nm. Related methods can be used to create, shorter nanorods, nanocrystals, and hollow nanospheres.
US09598280B2 Environmental sensor structure
A device in which an electronic circuit positioned within a cavity of a package housing is encased by a bubble restrictor material, with a media resistant material overlaying the bubble restrictor material. The bubble restrictor material functions to inhibit the formation and growth of moisture-related bubbles within the material, including at the interfaces of the material and surfaces within the package housing. The media resistant material is resistant to physical and chemical alterations by media within an external environment to which the device is exposed. The media resistant material and bubble resistant material function to transfer a sensed characteristic of the media to the electronic circuit.
US09598275B2 Pressure sensor and manufacture method thereof
A pressure sensor using the MEMS device comprises an airtight ring surrounding a chamber defined by the first substrate and the second substrate. The airtight ring extends from the upper surface of the second substrate to the surface between the first substrate and the second substrate and further breaks out the surface. The pressure sensor utilizes the airtight ring to retain the airtightness of the chamber. The manufacture method of the pressure sensor is also disclosed.
US09598274B1 Fuel distribution system and method
A system and method for distributing fuel, managing fuel transactions, and determining fuel pricing. The system includes a fuel tank and dispensing systems connected thereto for serving customers. The dispensing systems include a meter measuring a volume of dispensed fuel and a data subsystem that transmits transaction data for fueling transactions completed during a first period. A tank gauge measures an ending volume of fuel at the end of the first period. A management system uses the transaction data to generate a usage report and invoice for the customers based on fuel usage during the first period. The management system further monitors the gauge and determines a price for the ending volume of fuel and a variance based on the measured ending volume of fuel and an expected volume. The variance is used to determine a second price for fueling transactions completed during a second period following the first period.
US09598273B2 Liquid pressure reducing unit for beverage dispensing unit
A liquid pressure-reducing unit having a first half body with a contact surface and first groove extending over the contact surface is disclosed. The unit has a flexible resilient sealing element having a floor layer lining the floor of the first groove. The unit has a second half body with a contact surface and first and second walls extending out of the contact surface and defining a second groove. The contact surfaces of the first half body and second half body join, wherein the first and second walls penetrate into the first groove so that the free end of the first and second walls forms a fluid-tight contact with the flexible resilient floor layer lining the floor of the first groove, defining a fluid-tight channel bringing in fluid communication a fluid inlet with a fluid outlet. The channel is non-rectilinear and/or having a cross-section varying over the length thereof.
US09598272B2 Apparatus for transporting a load
An apparatus for transporting a load onto a raised surface includes: a frame; and rear, middle, and front wheel assemblies coupled to the frame. Each wheel assembly includes: at least one leg, at least one wheel rotatingly coupled to the leg for rollingly supporting the frame, and at least one actuator operatively coupled to the at least one leg. The front wheel assembly is configured to extend forwardly from, and retract rearwardly toward, the frame. The actuators are configured to independently raise and lower the at least one rear, middle, and front wheel. A load support member is located below the frame and moveable between a first position where the center of gravity of the load is located rearward of an axis defined by the at least one middle wheel, and a second position where the center of gravity of the load is located forward of the axis.
US09598265B1 Vertically and horizontally mobile elevator cabins
An elevator system permitting horizontal movement of a normally vertically moving elevator cabin, the elevator cabin being automatically attached to or detached from an elevator frame and horizontally moved to or from another elevator shaft or other destination. While an elevator cabin is supported on an elevator frame or other surface, various cables, rods, plugs and other equipment are automatically connected to or disconnected from the elevator cabin to enable vertical or horizontal motion of the elevator cabin. Once disconnected from such devices, the elevator cabin can be propelled horizontally out of the elevator frame and elevator shaft, onto other surfaces, such as floors of a building, and move horizontally to another destination. An elevator cabin may also be horizontally moved into an elevator shaft and onto the surface of an elevator frame, and connected to the frame, thus enabling such cabin to then move vertically within an elevator shaft.
US09598263B2 Elevator device
An elevator device includes a voice input device, a voice recognition device, a call registration device, and an announcement control device. Upon receipt of an announcement request for a second announcement having higher priority than a first announcement while the announcement control device is causing the announcement output device to output the first announcement, the announcement control device stops the first announcement and causes the announcement output device to output the second announcement. The announcement control device also determines whether the re-output of the first announcement is necessary. In the case where the announcement control device determines that the re-output of the first announcement is necessary, upon finish of the second announcement, the announcement control device causes the announcement output device to re-output the first announcement.
US09598262B2 Method for adapting a changing movement of a thread to a flange spool and spooling device
A method for adapting a travel end position of a changing movement of a thread to a flange spool includes means of which the thread is moved back and forth during a spooling operation along a rotation axis of the flange spool relative to the flange spool by means of a changing thread guide. The flange-side travel end position can be moved away from the flange of the flange spool in an axial direction when the thread tension decreases when the thread is moved away from the flange-side travel end position. Also, the flange-side travel end position can be moved by means of the changing thread guide in an axial direction towards a flange of the flange spool when the thread tension increases when the thread is moved away from the flange-side travel end position. Included is a spooling device for carrying out the disclosed method.
US09598261B2 Method and device for storing yarn in order to feed thread without creating twisting thereof
A method for supplying a thread to a textile machine without creating torsions thereof includes picking up the thread from a reel, winding it on a rotary drum driven by an electric motor thereof and supplying such thread to the textile machine, preferably at constant tension and/or quantity. The method provides for measuring the amount of thread leaving the rotary drum and the amount of thread wound thereon and intervening on the rotation of such drum so the amount of thread leaving the drum is equivalent to the amount loaded thereon to avoid the creation of torsion on the thread.A device for implementing such method is also disclosed.
US09598260B2 Image forming apparatus with creaser control, control method thereof, printing system, and non-transitory computer-readable medium
An image forming apparatus determines whether crease processing at a plurality of portions set on the sheet includes crease processing on two, front and back surfaces of the sheet; determines, if it is determined that crease processing includes crease processing on the two surfaces of the sheet, whether a connected post-processing apparatus that performs crease processing on a sheet can perform crease processing on the two, front and back surfaces of the sheet by one feeding; and controls, if it is determined that the connected post-processing apparatus cannot perform crease processing on the two surfaces by one feeding, to change, to one of the front and back surfaces of the sheet based on attribute information of the sheet, a surface to be processed in crease processing at the plurality of portions.
US09598256B2 Document validating/stacking device
A document validating/stacking device is provided that has a validator 1 provided with a swingable rocker 10 formed with a head 16 and a stacker 2 detachably attached to validator 1. Stacker 2 comprises an X-linkage 20 having a driver arm 41 that is separably pushed by head 16 in the same rotational direction as head 16 swings to expand X-linkage 20, to thereby move pusher plate 18 from the initial position to the extended position and to stow the document within interim chamber 24 into storage 7.
US09598253B2 Printing apparatus, control method therefor, and storage medium
A printing apparatus comprises a feeding roller configured to feed a printing sheet, a conveyance roller configured to convey the printing sheet, a printing unit configured to print on the printing sheet, a conveyance control unit configured to control conveyance of printing sheets so that a trailing edge of a preceding sheet and a leading edge of a succeeding sheet overlap each other, an acquisition unit configured to acquire, before completion of a printing operation of the preceding sheet, information of a leading edge position of the succeeding sheet, and a determination unit configured to determine whether to convey the succeeding sheet to a position facing the printing unit while keeping an overlap state between the preceding sheet and the succeeding sheet in accordance with the leading edge position of the succeeding sheet.
US09598250B1 Fall protection unit for forklift trucks servicing flatbed trailers
Each of a pair of barrier platforms is carried by a pair of carrier stanchions, one disposed to each opposite side of a loading bay in a warehouse environment for a flatbed trailer carrying pallets that must be loaded and unloaded by forklift trucks. Each pair of carrier stanchions also supports a motor that can be operated to raise and to lower, as desired, one of the pair of barrier platforms that in the lowered position provides fall protection for the forklift trucks that service the flatbed trailer. Each barrier platform includes a forklift rub rail and carriages that are configured to cooperate with the carrier stanchions to resiliently absorb impacts from collisions with the forklift.
US09598244B2 Conveyor chain support
Conveyor chain support for an easy to clean conveyor, where the conveyor chain support comprises an outer peripheral sliding surface adapted to glidingly support a conveyor chain in a return path of the conveyor, where the conveyor chain support is adapted to be attached on a transverse axle of the conveyor in a support position and where the conveyor chain support is a single piece comprising a first jaw and a second jaw joining each other at one end and forming a mouth at the other end, where the conveyor chain support is adapted to be attached on the transverse axle through the mouth. In this way, a conveyor chain support that allows for an easy cleaning of a conveyor is provided for. Such conveyors are e.g. used in the food industry.
US09598235B2 Motor vehicle for collecting and sorting material and method of doing same
A motor vehicle for collecting and sorting material includes at least one container disposed in a material-storage compartment of the motor vehicle, a bin tipper configured to receive a collection bin containing the material, and a hopper configured to receive the material from the collection bin and transport the material to a selected location in the material-storage compartment of the motor vehicle.
US09598233B2 Cover system with tethering
In accordance with one implementation, a floating cover system includes a plurality of cover-tethering mounts mounted along the periphery of a holding tank. Each of the cover-tethering mounts includes a guide portion insertable through a cover-holding element that is attached along a periphery of a holding tank cover. When secured to the plurality of cover-tethering mounts, the holding tank cover can rise and fall within the holding tank responsive to volumetric changes in the liquid and/or gas contained in the holding tank.
US09598232B2 Food or beverage card comprising an actuator
The present invention relates to a Card for containing food or beverage ingredients comprising: a substantially planar and rigid base portion, at least two ingredient compartments for storing the ingredients and at least two discharge portions, each discharge portions being linked to one of the compartments and extending along the plane of the base portion, and at least one sealing member provided on the base portion covering the compartments and discharge portions on the base portion side of the card, wherein the card is designed for insertion in a food and beverage preparation device in order to dispense the ingredients from the compartments via the discharge portions. The invention further relates to a food and beverage preparation system, comprising a card according to the invention and a food and beverage preparation device, as well as to a method for preparing food or beverages using the card.
US09598231B2 Cup-shaped body for a capsule for preparing a beverage
A cup-shaped body comprises a circumferential wall and a first end wall. The first end wall comprises a deepened portion, forming a first recessed space. The first end wall further comprises a projection protruding from said deepened portion into said first recessed space. The body is formed such that identical specimens of the body are slidable into one another. The deepened portion is formed to comprise abutment structure having an abutment condition in which the extent of said slidability of a first one of said specimens into a second one of said specimens is limited.
US09598226B2 Dispenser
A disposable dispenser unit is disclosed. The disposable dispenser unit comprises a fluid reservoir, a tag for storing information, a dispenser head having a pump chamber and at least one injector nozzle, and a means disposed at the dispenser head for attachment thereof to a diagnostic system, wherein the pump chamber comprises a piston and the piston comprises a volume which can be filled with fluid.
US09598223B2 Plunger for pneumatic dispenser
A plunger is fittable within a cylinder of a pneumatic dispenser that discharges a viscous material. The plunger has a first portion located at the front, and a second portion located at the rear. The second portion is a hollow structure and has a circumferential wall. An inner circumferential surface of this circumferential wall has a tapered surface. The circumferential wall has a thickness dimension that decreases in the axial direction moving away from the first portion. Therefore, the circumferential wall easily displaces in the radial direction, because the bending stiffness decreases in the axial direction moving away from the first portion. The first portion is a solid structure that is more rigid than the second portion. The first portion also has a partition wall surface that separates the inner chamber of the second portion from the solid section of the first portion.
US09598219B2 Enclosure
An enclosure, wherein the enclosure is at least partly formed of a layered material (3), the inner layer (1) of the layered material being formed of porous metal and the outer layer (2) of the layered material being formed of hygroscopic porous material.
US09598216B2 Web and method for making fluid filled units
A web, method, and apparatus for forming dunnage units. The web includes first and second elongated layers. A plurality of seals that hermetically join the first elongated layer to the second elongated layer to form a plurality of inflatable pouches and an inflation channel that is in fluid communication with pouches and is disposed outside of the pouches. An inflation side line of perforations, a gap forming area, and an opposite side line of perforations are arranged in a line between pair(s) of the pouches.
US09598210B2 Reservoir pressure equalization systems and methods
Various embodiments of the present invention are directed to equalizing pressure in a reservoir containing fluidic media, possibly due to imperfect installation of the reservoir or an external influence such as an altitude or a temperature change. In various embodiments, fluidic media may be expelled from the reservoir through a needle and contained in an interior volume of a pierceable member before the needle pierces the pierceable member to establish a flow path to a user. In other embodiments, fluidic media may be expelled through a port of the reservoir into a chamber or to the outside environment. In further embodiments, fluidic media may be expelled through a channel in a plunger head and out a passage in the reservoir when the channel and passage are aligned. In other embodiments, fluidic media may be expelled through a valve, and the valve may be pierceable by a needle to establish a flow path to the user.
US09598207B2 Waste-disposal device
A waste-disposal device for use with a bag unit of the type having an annular component from which a free end of tube extends to form a bag. The waste-disposal device comprises a bin having an open top end for accessing an inner cavity of the bin. A support is in the bin adjacent to the open top end and adapted to support the annular component of the bag unit for waste to be received in the bag of the bag unit extending in the inner cavity of the bin, by passing through a central opening thereof. A closing mechanism comprises a door pivotally connected to the support by at least one pivot and an abutment surface in the bin, a pivot axis of the at least one pivot being located at a same height or higher than a bottommost edge of the annular component of the bag unit when received in the support and when the bin has a bottom thereof on the ground. The door is pivotable between a closed position in which the door presses the bag toward the abutment surface to close the bag, and an open position in which the door is away from the abutment surface to open the bag.
US09598206B2 Container including an arched bottom having a square seat
The invention relates to a container made of a plastic material, provided with a body (5) and a bottom (6) extending at a lower end of the body (5), wherein the bottom (6) includes: an annular seat (7) extending substantially away from the body (5) and defining a support surface (8) and an inner annular flange (11) substantially perpendicular to the support surface; a concave arch (13) which extends from an area adjacent to the seat (7) towards a central area (14). The axial dimension H of the flange and the radial dimension L of the support surface are such that: formula (I). 0.6 ≤ L H ≤ 1.5 ( I )
US09598203B2 Injection container storage box device and injection container picking system including the device
An injection container storage box device that stores a plurality of cylindrical injection containers randomly loaded includes: a housing of which the upper and lower ends are open; and an opening/closing plate disposed in a lower end portion of the housing so as to freely slide to open and close a lower end opening, on which the injection containers are placed, wherein the opening/closing plate includes a corrugated surface in which a plurality of convex portions and a plurality of concave portions alternate continuously in a predetermined direction and the injection containers are put into a toppled state using the corrugated surface.
US09598202B2 Carton with handle
A carton for containing a flowable material. The carton comprises a plurality of panels that extends at least partially around an interior of the carton. The plurality of panels comprises at least a top panel. At least two end flaps are respectively foldably attached to respective panels of the plurality of panels. The at least two end flaps comprise a top end flap foldably connected to the to panel. An integrated handle comprises a handle panel extending in the top panel and into the top end flap and a handle closure at least partially in face-to-face contact with at least the top panel. The handle panel overlaps at least a portion of the handle closure, and the handle closure at least partially forms a barrier in the top panel adjacent the handle panel for at least partially preventing flowable material from exiting the carton at the integrated handle.
US09598201B2 Container comprising an arched base having a star-shaped cross-section
A container of plastic material, having a body extending along a principal axis and a bottom in the extension of the body at a lower end thereof. The bottom has an annular seat defining a seating plane; and a conical arch that extends from near the seat towards the interior of the container to a central apex, the arch having in transverse cross-section a star-shaped profile inscribed between two circles, the ratio of the diameters of which is greater than or equal to 0.7.
US09598200B2 Connection die coupled with container neck in use
Disclosed is a connection device to be coupled with a container neck in different standards for use. The connection device is formed with a mouth part at the upper side and a screw thread part at the lower side. The mouth part at the upper portion of the connection device is formed in a screw thread or other shape in the standard corresponding to a bottle lid, and the inside of the screw thread part is formed with a screw thread corresponding to the standard of the container neck. The screw thread is integrally formed or an elastic screw thread is additionally added for the coupling with the necks of a plurality of containers.
US09598193B2 Clipping device and method controlling said clipping device
A clipping device is provided for closing at least one closure, like a closure clip, in a packaging machine, for closing tubular or bag-shaped packaging casings as well as a method for controlling a clipping device. The clipping device includes a first closing tool and a second closing tool, wherein at least the first closing tool is reversibly movable towards the second closing tool, between an opened position and a closed position, for closing the at least one closure means and a drive for reversibly moving at least the first closing tool towards the second closing tool in a closing direction. In the clipping device, a monitoring device is provided in the region of the second closing tool for monitoring the second closing tool being prepared for the next clipping cycle.
US09598192B2 Bag mouth opening method and apparatus for use in bag filling and packaging
Provided are a bag mouth opening method and apparatus capable of surely and stably opening into a desired shape the mouth of a spout bag having a spout attached to an upper edge-side portion thereof. A spout tilting relative to a bag is corrected into a non-tilting position and pinched with spout pinching members opened and closed by a first air cylinder of a spout holding device. The first air cylinder is held in an initial position in the width direction of the bag by a second air cylinder through a quadric link comprising a connecting rod mounting plate, a connecting rod, a connecting plate, and a second support arm. The interior of the second air cylinder is opened to the atmospheric pressure in synchronism with the start of movement away from each other of a pair of suction cups of a bag mouth opening device and movement toward each other of a pair of gripping members gripping the laterally opposite side edges of the bag. Consequently, the first air cylinder and the pinching members attached thereto become free to move in the width direction of the bag and thus are moved through the bag in accordance with the movement of the gripping members.
US09598188B2 Vertical packaging machine for food products
A packaging machine comprising a transversal sealing unit (20) of bags, substantially consisting of a plate support (21) which comprises a series of additional supports and kinematic organs for the horizontal and vertical activation of grippers (22, 23), one internal and the other external, for the sealing and cutting of each bag, said machine comprising motors (25, 26), mounted on a fixed support (24), which cause the vertical movement of a main carriage (29) and of a gripper carriage (30) by means respectively of a screw shaft (27) and a screw shaft (28), said main carriage (29) supporting two pairs of horizontal and sliding parallel arms (33, 34), the internal first of which control the horizontal movement of the internal grippers (22) and the second control the horizontal movement of the external grippers (23), while the vertical movement of the grippers to follow the moving bag is achieved by the vertical movement of the main carriage (29).
US09598181B2 Device for fastening a fluid transport circuit to an element of the structure of an aircraft and related aircraft
A fastening device (10) is disclosed for attaching a fluid transport circuit to an element of a structure of an aircraft, with the fluid transport circuit containing two portions (23, 42), each of which is made up of an external tube (22, 44) positioned around an internal tube (21, 43). The fastening device (10) is positioned at a connection (40) between the two portions (23, 42) of the fluid transport circuit, and contains a body (26) with a plate (27) to attach the fastening device (10) to an element (61) of the structure of the aircraft. The body (26) provides at least one sealed connection between the external tubes (22, 44) of the two portions (23, 42) and a support system provides a constant radial clearance between the internal tubes (21, 43) and the external tubes (22, 44) of the two portions (23, 42) of the fluid transport circuit.
US09598180B1 Aircraft landing clearance indication system
The aircraft landing clearance indication system is constructed of a faceplate that is adapted to be secured against a surface in a cockpit. The faceplate includes a front surface that includes instructions as to operation of the system. A push button is mounted on the front surface of the faceplate. Depression of the push button illuminates the push button providing an instantaneous feedback as to the authorization of the respective airplane to land on a runway. Once the airplane has landed, the push button is depressed a second time in order to reset itself for future use. The aircraft landing clearance indication system is used during the landing checklist.
US09598173B2 Tow plate and AVC housing
A tow plate and active vibration control (AVC) housing configured to couple to a helicopter sponson about an AVC and support a gun mounting system.
US09598172B2 Aerial material distribution device
A device is provided. The device includes one or more electric sifters externally mounted to an aircraft and configured to store a payload. Each electric sifter includes a loading port to add the payload and a distribution apparatus to distribute the payload when the aircraft is airborne. The device also includes an uploaded program, configured to control the aircraft and the device. The uploaded program directs the aircraft to land at a designated location in response to a payload of a designated one of the one or more electric sifters reaching a predetermined level. In response to the device receives a command to activate the distribution apparatus, the distribution apparatus distributes the payload from the device.
US09598171B2 Vehicle with aerial and ground mobility
A combination rotor and wheel assembly for an unmanned vehicle with ground and aerial mobility has a rotor arm adapted to be attached at an inner end thereof to a vehicle body. A rotor is rotatably connected to an outer end of the rotor arm about a rotor axis, and a rotor drive mounted on the rotor arm rotates the rotor such that the rotor exerts an upward lift force on the rotor arm. An open spoked wheel is rotatably connected about the rotor axis independent of the rotor The diameter of the wheel is greater than that of the rotor, and a bottom edge of the wheel is below the rotor. A wheel drive rotates the wheel. Vehicles can have various numbers and orientations of the rotor and wheel assembly to provide aerial and ground mobility.
US09598170B2 Kite ground station and system using same
A kite system with a ground station adapted for airborne power generation. The kite system may include a kite which includes one or more airfoils which have mounted thereon a plurality of turbine driven generators. The turbine driven generators may also function as motor driven propellers in a powered flight mode, which may be used during take-off, which may include aspects of vertical take-off and landing. A perch adapted to facilitate the take-off and landing may be used as part of the system. The perch may pivot such that the pivot is oriented towards the tension direction of the tether.
US09598166B2 Window of an aircraft with an electromagnetic shield
A window of an aircraft having electromagnetic shielding performance and environment-resistant sealing performance, an aircraft, and an assembly method for a window of an aircraft are provided. A conductive seal member (60) is provided so as to face and surround the peripheral side surface of a window panel and is sandwiched between a conductive film (41) and an outer retainer (22). In the conductive seal member (60), thin wire materials (62) made of a conductive material such as aluminum are embedded in a seal member body (61) made of a material, such as silicone rubber, having an electric insulating property, waterproofness and pliability. An electromagnetic shielding effect, and environment-resistant sealing properties such as an electric insulating property and waterproofness can be both ensured by the conductive seal member (60).
US09598156B2 Watercraft light, housing, and method
A watercraft light, light housing, and method of installation is disclosed herein. The watercraft light comprises at least one light disposed in a unitary longitudinally extending housing having a first side and a second side. The first side of the housing comprises an outwardly extending portion configured to be placed into a rub rail track between separate sections of a rub rail bumper and to hold the at least one light substantially therein. The second side of the housing is configured to transfer light and comprises longitudinally extending portions that extend beyond each of the longitudinal ends of the outwardly extending portion of the first side. The watercraft light comprises a connector configured to connect and hold the watercraft light to the watercraft.
US09598154B2 Float
A novel float that can be constructed in pieces. Each piece providing buoyancy and when joined together able to provide floatation for a structure. The float having containers that can serve as storage for different materials. The floats making a system used to float a large structure such as a home.
US09598150B2 Apparatus and method for exchanging a buoy bearing assembly
A buoy includes a turret coupled to a buoyant body using a bearing assembly; a deckhouse disposed on the buoyant body; and a bearing retainer configured to retain the bearing assembly and to releasably attach to the turret. The buoy may also include a locking mechanism having an inner opening in the turret, an outer opening in the buoyant body, and a locking member configured for insertion through the inner and outer openings. In one embodiment, the inner opening is out of alignment with the outer opening during operation of the buoy. The buoy may further include a detachable cover on the deckhouse, wherein the cover is configured to attach to the bearing retainer.
US09598145B1 Inflatable drift boat
An inflatable hull fabricated from a drop stitch material is configurable to either a dory or drift boat. The inflatable hull has oarlocks which may be placed within urethane mounts, which are glued or thermally bonded to the fabric making up the gunnels of the boat, thereby eliminating any need for a stiff frame for attachment of oars to the craft. The inflatable hull may have internal structures, such as seats, thigh braces and panels, which are also fabricated from drop stitch material as an integral unit with the hull. Alternatively, the seats, thigh braces and panels may be fabricated as attachable and detachable components which allow a single hull to be utilized either as a dory or a drift boat.
US09598143B1 Hybrid hydraulic-operated bicycle
A hydraulically-powered bicycle having a frame, handle bars, a front tire, and a hydraulically powered drive wheel. The drive wheel is powered by oil from a sump which is pressurized by a pair of foot-operated pumps. An accumulator selectively stores and releases energy stored in a spring under the control of a control valve. When released the stored energy provides an energy boost to the bicycle. The pumps are dual piston devices that selectively couple a second piston to a first piston. The pumps implement a power control using the dual pistons. Coupling the pistons together is performed by a linkage assembly having linkage arms and linkage pivots.
US09598139B2 Bicycle operating device
A bicycle operating device comprises a mounting clamp and an adapter member. The mounting clamp is configured to be mounted to a bicycle tube member and comprises a first radius portion, a second radius portion, and a clamp opening. The first radius portion defines a first inner radius. The second radius portion defines a second inner radius different from the first inner radius. The bicycle tube member is to extend through the clamp opening. The clamp opening is defined by the first radius portion and the second radius portion. The adapter member is configured to be provided between the second radius portion and the bicycle tube member in a state where the mounting clamp is mounted to the bicycle tube member.
US09598135B2 Cowl of saddle-ridden type vehicle
A cowl which covers a front component of a saddle-ridden type vehicle, includes: a cowl body; and passage forming portions each of which extends from a front, central, in a left-right direction, position of the cowl body or a vicinity of the front, central position to a side position of the cowl body; each of the passage forming portions forms an air passage that extends from the front, central position of the cowl body or a vicinity of the front, central position to the side position of the cowl body; the passage forming portions or each of the passage forming portions has an inlet as defined herein; each of the passage forming portions has an outlet as defined herein; and the air passages cause a riding wind occurring during running of the saddle-ridden type vehicle to flow through the air passages.
US09598129B2 Straddled vehicle
An increase in the size of a body portion of a straddled vehicle forward of a steering shaft in a left-right direction and a front-rear direction of a body frame is suppressed to secure a space forward of the steering shaft. Each top end of left optical lens body 35L and right optical lens body 35R is located below top edge B1 of an upper bracket in an up-down direction of the body frame. Each bottom end of left optical lens body 35L and right optical lens body 35R is located above bottom edge B2 of a lower bracket in the up-down direction of the body frame. The left end of left optical lens body 35L is located on the right of left edge B3 of a left front-wheel support unit in the left-right direction of the body frame. The right end of left optical lens body 35L is located on the right of right edge B5 of the left front-wheel support unit in the left-right direction of the body frame. The left end of right optical lens body 35R is located on the left of left edge B4 of a right front-wheel support unit in the left-right direction of the body frame. The right end of right optical lens body 35R is located on the left of right edge B6 of the right front-wheel support unit in the left-right direction of the body frame.
US09598126B2 Automatic auxiliary axle control system
An automatic auxiliary axle control system is disclosed for a load-transporting motor vehicle having two or more primary axles and one or more auxiliary axles wherein the control system detects a noncompliant axle carrying weight condition when the weight of the vehicle acting on any one of the primary axles exceeds a prescribed maximum allowable axle carrying weight assigned to that axle and also when the weight acting on any group of the axles arranged consecutively exceeds a prescribed maximum allowable axle group carrying weight assigned to that axle group. And the control system on such detection effects auxiliary axle usage that results in no maximum allowable axle carrying weight and maximum allowable axle group carrying weight being exceeded provided the current gross vehicle weight does not exceed a prescribed maximum allowable gross vehicle weight determined by all of the axles and the current center of gravity of the vehicle is located within a certain compliance-manageable range. And with the control system also capable of effecting auxiliary axle usage outside this range suited to the existing condition, providing control over auxiliary axle usage by an operator of the vehicle, and producing useful information.
US09598120B2 Vehicle interior board and method for manufacturing the same
Included are a first board and a second board that include hard polyurethane foam layers and formed respectively in spaces sandwiched between pairs of thin plates, and a coupling member having a porous structure where a recessed groove is formed, parts of the coupling member being arranged in the spaces. The hard polyurethane foam layers are also formed in gaps between the thin plates and the coupling member to join the boards to the coupling member. Consequently, the step of molding the first board can mold, join, and integrate the boards, and mold a bendable, lightweight, and very strong vehicle interior board.
US09598119B2 Vehicle body reinforcement structure
A vehicle body reinforcement structure includes a dash panel separating an engine compartment and an interior of a vehicle. A floor member extends in a longitudinal direction of the vehicle and is in closely contact with a floor of a vehicle body to reinforce rigidity of the floor of the vehicle body. A front side member extends in the longitudinal direction of the vehicle is connected to and overlaps with the floor member inside the dash panel.
US09598118B2 Vehicular floor brace
A vehicle floor brace has a tubular body formed by rounding a sheet metal material, and a pair of attachment portions made of the sheet metal material and formed integrally with the tubular body at both ends in a longitudinal direction of the tubular body, and the vehicle floor brace is fixedly attached to an underside of a floor panel of a vehicle via the attachment portions to reinforce the floor panel, each of the attachment portions being configured to include a flat portion having an attachment surface to be attached to the floor panel, and a pair of reinforcing flanges formed by bending both side portions of the flat portion at right angles so that the side portions extend downward to an opposite side from the attachment surface and so that the attachment portion has a dish-shaped section.
US09598114B2 Vehicle fender energy absorbing apparatus
An energy absorption member coupled between a vehicle front fender and a vehicle side structural member providing peak impact force resistance and energy absorption during an impact force imposed on the front fender. The energy absorption member extends continuously along the length of the front fender opposed from the side structural member to provide constant load along the entire length of the front fender. The energy absorption member may be a foamed block, a vertical, or horizontal oriented honeycomb structure or spaced hollow crush lobes.
US09598110B2 Vehicle storage compartment assembly
A vehicle storage compartment assembly has a bottom wall, a first and second upright walls and a top wall. The first upright wall, the second upright wall and the top wall are each formed with a breakaway structure. A first section is defined on a first side and a second section is defined on a second side of the breakaway structure. The bottom wall extends from the first section to the second section in the absence of the breakaway structure. The first section, the second section and the bottom wall define a storage space. The breakaway structure is configured such that in response to one of the first section and the second section receiving an impacting force the breakaway structure breaks separating the first section from the second section along the first upright wall, the second upright wall and the top wall.
US09598107B2 Lightweight vehicle beam
Several different cross sections of beam having more than four sides are disclosed that may form a central portion of a beam having end portions that have four sides. The end portions of the beams may be received by frame rails. The central portion of the beam between the frame rails may be formed with more than four sides. The additional sides may be recessed beads or protruding ribs. Beams having arcuate recesses or arcuate ribs may be provided on the central portion of the beam. The end portions of the beams may extend outboard of the frame rails. The ribs or beads on the central portion of the beam may provide equivalent performance to four-sided beams having considerably thicker walls. Weight reduction is achieved because the central portion is made of a thinner material while retaining strength by forming beads or ribs in the central portion.
US09598100B2 Device for connecting a steering column to a crossmember
A device for connecting a steering column to a cross member positioned between two A-pillars. The device comprises a front connecting region, a cross member-accommodating region, and a rear connecting region. The device comprises at least one metal structure, which is designed as a bow or comprises at least one such bow, extending from the front connecting region to the rear connecting region. A base body supports the metal structure. The metal structure is substantially the main load path for introducing force into the cross member. The base body is connected to the metal structure in at least the front connecting region and rear connecting region, in the direction of the main load path.
US09598099B2 Handle
Handle consisting of a gripping knob internally provided with a housing cavity in a stable position of a pin, the pin consisting of at least a portion with a larger-diameter section and of a portion with a smaller diameter projecting therefrom. At the top end of the smaller-diameter portion, a retaining member is provided, having a larger diameter with respect to that of the smaller-diameter portion. An elastic bush is housed on the smaller-diameter portion for engagement with the inner surface of the knob. Between the retaining member and the elastic bush, a washer is arranged of a material aimed at minimizing friction.
US09598097B2 Shopping cart
A cart includes a chassis and attached wheels; an upper basket attached to the chassis; and a lower basket attached to the chassis. In some embodiments, the cart includes no widthwise push bar in a rear of the cart such that access is unobstructed to the upper and lower baskets from the rear of the cart by a person. In some embodiments, the chassis defines on each lateral side of the cart a pair of vertically spaced handles, each handle surrounding and defining an opening. The handles preferably include handle bars shaped in an oval. On each cart side a curved elongate member extends between and connects the handles, and the curved elongate members represent the rearmost part of the cart. The rear area of the upper basket defines a seat for an infant, and a rear ledge of the lower basket defines a seat for a toddler.
US09598092B2 Railcar energy absorption/coupling system
A railcar energy absorption/coupling system including a cushioning assembly arranged in operable combination with a coupler and a yoke. The cushioning assembly is positioned in a draft pocket defined by a draft sill on a railcar between the front and rear stops. The yoke consists of a back wall along with top and bottom walls which are joined to and axially extending from the back wall toward a forward end of the cushioning assembly. The back wall of the yoke is disposed to contact the rear end of the cushioning assembly. The top and bottom walls of the yoke are operably coupled to a shank portion of the coupler toward a forward end of the yoke. The top and bottom walls of the yoke each include stop members which extend in opposed lateral directions from each other and limit draft travel while maximizing buff travel and limit total combined travel of the energy absorption/coupling system. The energy absorption/coupling system has a neutral position, a full buff position disposed a first predetermined distance from the neutral position, and a full draft position disposed a second predetermined distance from the neutral position, with the full buff and full draft positions for the energy absorption coupling system being disposed in opposite directions from the neutral position.
US09598091B2 Air intake system for an engine
An air intake system is disclosed. The air intake system may have an air box. The air box may be configured to receive air from an ambient. The air intake system may also have a filter assembly disposed within the air box. The filter assembly may be configured to clean the air. In addition, the air intake system may have a duct. The duct may have a first duct end configured to receive the air exiting the filter assembly. The duct may also have a second duct end configured to deliver the air to the engine. The second duct end may be located at a gravitationally higher position than the first duct end.
US09598088B2 Driver assistance apparatus capable of recognizing a road surface state and vehicle including the same
A driver assistance apparatus and a vehicle including the same are disclosed. The driver assistance apparatus includes a stereo camera, a memory to store road surface data regarding a state of a road surface classified into a dry state, a wet state, a snow covered state, and an icy state, and a processor to classify the state of the road surface as any one of the dry state, the wet state, the snow covered state, and the icy state based on stereo images received from the stereo camera and the road surface data. Consequently, it is possible to recognize a current road surface state.
US09598082B2 Coasting control device and method for vehicle
In consideration of an amplification effect of a braking force at the time of brake operation, upper-limits (α, β) of a brake operation force (Brk) with which the execution of free-run coasting and neutral coasting is started may be different, on the basis of whether or not a brake booster can be filled with a negative pressure. Therefore, while the braking force at the time of brake operation is secured, the range of the brake operation force (Brk) with which coasting is executed can be enlarged, and an improvement in fuel economy can be made.
US09598080B2 Self-propelled civil engineering machine and method of controlling a civil engineering machine
A civil engineering machine and a method of controlling the machine are based on the position of at least one reference point which is relevant to the control of the civil engineering machine being changed, as the civil engineering machine moves, as a function of a relative position of the at least one reference point relative to a desired path of travel.
US09598079B2 Engine control device
The engine control device is applied to a vehicle equipped with a suspension control device for driving stepping motors for changing damping forces of shock absorbers. The suspension control device performs an initializing process for resolving the step-out of the stepping motors by driving the stepping motors when an initialization performing condition is satisfied. The engine control device continues the engine operation when a signal for inhibiting the automatic stop of the operation of the engine is sent to the engine control device and the engine control device judges that no malfunction occurs in the suspension control device even if the engine stop condition is satisfied. The engine control device automatically stops the operation of the engine when the engine stop condition is satisfied and the engine control device judges that a malfunction occurs in the suspension control device even if the signal is sent to the engine control device.
US09598078B2 Alerting predicted accidents between driverless cars
This patent application discloses methods and systems for alerting computerized motor-vehicles about predicted accidents. In an example method, a motor vehicle alerts another motor vehicle about a predicted accident, even though that accident is between the alerting car and a third motor vehicle—for example, the alert is transmitted by non-visual electromagnetic (EM) radiation. When an adjacent motor vehicle receives such accident alert and determines it might itself be hit, it will react so as to minimize its chances of being hit or at least to minimize the damage if it is being hit.
US09598076B1 Detection of lane-splitting motorcycles
A controller for an autonomous vehicle received audio streams from one or more microphones and one or more image streams from one or more cameras. The audio streams are processed to identify audio features that potentially correspond to a motorcycle. The video streams are likewise processed to identify image objects that have movement and/or visual attributes corresponding to a motorcycle. The audio features and image objects are correlated. If a correlation is identified among the audio features and image objects, then a potentially lane-splitting motorcycle may be determined to be proximate. Actions may be taken to avoid collision with the lane-splitting motorcycle, such as avoiding lane changes, signaling longer, or performing lane changes more slowly.
US09598067B2 Control strategy for AWD connection and disconnection
The invention relates to switching between 2WD and 4WD of a vehicle. It is suggested to increase output power of an engine (106) when changing to 4WD. An AWD coupling (120) is opened, if not already open. To provide 4WD, a PTU clutch (108) is engaged once engine power has increased. The other couplers are sequentially engaged.
US09598065B2 Internal combustion engine controller, and control system and method of controlling an internal combustion engine
An engine controller for controlling an internal combustion engine having a plurality of cylinders is provided. The engine controller is in signal communication with the internal combustion engine, an automatic transmission, and a displacement adjusting mechanism. The engine controller is configured to determine an operating condition of the internal combustion engine and to communicate with the automatic transmission to shift to one of a plurality of gear configurations, and the displacement adjusting mechanism to one of activate and deactivate at least one cylinder. The engine controller determines that a shift from a first gear configuration to a second gear configuration requires a positive torque when the at least one cylinder is deactivated. The engine controller communicates with the displacement adjusting mechanism to activate the at least one deactivated cylinder such that the plurality of cylinders are activated before the shift between gear configurations and the positive torque are completed.
US09598063B2 Method for braking a motor vehicle
A motor vehicle braking method wherein the vehicle includes a brake operating unit generating a braking signal based on brake pedal travel. The method includes the step of measuring the vehicle deceleration and pedal position during vehicle braking and determining an actual ratio between the measured deceleration and pedal position. In addition, a target ratio is provided based on vehicle deceleration for a defined pedal position. Wherein the actual ratios compared with the target ratio and a braking adjustment is provided when the actual ratio deviates from the target ratio.
US09598062B2 System and method for controlling a vehicle
A method for vehicle control comprises determining a braking capability of a braking system of a vehicle, and modifying application of at least one control parameter by a control system of the vehicle based on the determined braking capability. Braking capability may be determined by activating the braking system of the vehicle to apply a braking force on the vehicle, and concurrently, applying a level of tractive effort of the vehicle that is sufficient to overcome the braking force. The braking capability is determined based on the level of tractive effort.
US09598061B2 Electrohydraulic or electromechanical motor vehicle control device
The invention relates to an electrohydraulic and/or electromechanical motor vehicle control device (I), in particular for a motor vehicle brake system, including an electronic control unit (4), which is connected to a hydraulic unit (3) or at least to one electrically conductive housing part. The electronic control unit includes at least one first circuit board (5) for accommodating electrical or electronic components and includes at least one connecting plug (8), which electronic control unit is further characterized in that at least one electrically conductive connecting contact (6) is provided, which is connected to at least one electrically conductive fastening means (8) in such a way that there is an electrically conductive connection between the electrically conductive main body of the hydraulic unit (3) and/or the housing part and the reference potential of the circuit board (5) of the electronic control unit (4).
US09598060B2 Safety brake system for trailers
A safety brake system for a trailer comprises a brake unit to brake the trailer. An actuation unit comprises a mount secured to a front end of the trailer. A brake interface is operatively supported by the mount for displacement with respect to the trailer. The brake interface is displaceable toward a deactivation state in which the brake interface releases the brake unit from braking the trailer. A probe is operatively supported by the mount for displacement with respect to the trailer, the probe being displaceable between a hitching state in which the probe is adapted to contact the hitch of a vehicle, and a blocking state in which the probe blocks a hitch coupler of the trailer to prevent hitching of the trailer to a vehicle A biasing unit biases the probe against the hitch of the trailer in the hitching state and toward the blocking state. A mechanism operatively connects the brake interface to the probe, the mechanism retaining the brake interface in the deactivated state when the probe is in the hitching state, the mechanism releasing the brake interface from the deactivated state when the probe moves to the blocking state. A method for deactivating a safety brake is also provided.
US09598056B2 Adapter for wiper and wiper system thereof
A wiper adapter detachably coupled between a wiper arm and a wiper having a pivot shaft, the adapter comprises a first coupling element and a second coupling element. The first coupling element has a shaft cavity provided with a notch that is in communication with the shaft cavity; the pivot shaft can be assembled into the shaft cavity radially through the notch and can pivotably fit in the shaft cavity. The second coupling element can snap to the pivot shaft so as to prevent the pivot shaft from leaving the shaft cavity through the notch.
US09598052B2 Device for securing a blade on a wiper
The invention relates to a securing device (11) provided between a blade (1) and a mounting (4) constituting a wiper, wherein said device includes a first portion (12) that can be attached onto the mounting (4) and a second portion (13) that can be attached onto the blade (1), the first portion (12) and the second portion (13) being connected together by a removable attachment means, characterized in that the first portion (12) includes at least one blocking means capable of plugging at least one liquid-feeding device (6) which is a component of the wiper. The invention can be used for motor vehicles.
US09598051B2 Power consumption suppression system for electronic key terminal and power consumption suppression method for electronic key terminal
A power consumption suppression system enables effective reduction of power consumption of an electronic key terminal. A position information acquisition section (210) provided on an electronic key terminal (200) acquires locking location information concerning the locking position of a vehicle (100) and terminal location information concerning the position of the electronic key terminal (200). A power consumption suppression section (220) provided on the electronic key terminal (200) reduces the power consumption when the distance between the locking location of the vehicle (100) indicated by the locking location information and the location of the electronic key terminal (200) indicated by the terminal location information is equal to or longer than a prescribed distance.
US09598048B2 Webbing take-up device and seatbelt device
There is provided a webbing take-up device including (1) a take-up shaft, (2) an attachment and detachment detection unit, (3) a motor, (4) a first transmission unit that transmits rotation of the output shaft in a first direction to the take-up shaft, (5) a second transmission unit that transmits rotation of the output shaft in a second direction to the take-up shaft, and that also transmits the output torque of the output shaft to the take-up shaft such that the take-up torque of the take-up shaft does not reach a preset first torque, and (6) a control unit that, in cases in which engagement between a tongue and a buckle has been detected, controls a drive voltage and a drive current such that the output shaft rotates in the first direction, and the take-up torque of the take-up shaft reaches a second torque higher than the first torque.
US09598046B2 Vehicle assembly
A vehicle assembly comprising a vehicle body panel and hinge means connecting the vehicle body panel to a vehicle structure, spacing means arranged with the hinge means for maintaining at least a part of the vehicle body panel in a predetermined spacing from the vehicle structure when the hinge means is in a first position, the spacing means being configured to suffer substantially brittle failure when a predetermined load is applied thereto.
US09598044B2 Far side airbag device
A far side airbag device includes: a side airbag that is configured to receive a gas supply and, while being supported at a seatback of a seat, expand and inflate at a vehicle width direction middle side relative to a range at least from the chest to the head of an occupant of the seat; and a limiting structure that limits a thickness in the vehicle width direction of the side airbag in an inflated and expanded state such that a region that inflates and expands at the vehicle width direction middle side relative to the head of a small occupant is thinner than a region that inflates and expands at the vehicle width direction middle side relative to the head of a large occupant.
US09598038B2 Air bag system
An air bag system includes: a pad including a ceiling wall portion which covers an air bag and a side wall portion which extends into a cylindrical shape; a mounting base which holds the pad and holds the air bag by causing an annular retainer; and switch members which make up a horn switch mechanism so that the mounting base is mounted on a steering wheel main body, wherein: the switch members are provided below the air bag; and movable-side members are provided so that a portion at a side facing the inlet opening on an upper side thereof is brought into abutment with the retainer via a circumferential edge of the inlet opening of the air bag and a portion at a side thereof is brought into abutment with a lower surface of the side wall portion of the pad.
US09598029B2 Band clip and assembly
A band clip (1000) that suppresses projection from a sheet includes a binding band (1020) and a clip (1021). The binding band (1020) includes a head (1040) and a strap (1041) and the clip (1021) includes retainers (1060) as linear objects, a penetrating body (1061) as a linear object and a piercing stopper (1062) as a plate-like object. One end of the penetrating body (1061) is coupled to a base end of each of the retainers (1060). The retainers (1060) are respectively at an angle not larger than 90° to the penetrating body (1061), arranged in a distributed manner in a circumferential direction and resiliently deformable to extend along the penetrating body (1061). Another end of the penetrating body (1061) is coupled to a first principal surface (1160) of the piercing stopper (1062). The head (1040) is coupled to a second principal surface (1161) of the piercing stopper (1062).
US09598027B2 Cladding element for vehicle floor area
The present disclosure relates to a cladding element including several layers for a floor area of a luggage compartment in a vehicle, with a cover layer facing the luggage compartment, an acoustic foam layer facing the vehicle body, and a heavy layer arranged between the cover layer and the acoustic foam layer, which further includes a carrier layer of a foamed thermoplastic material, which is arranged between the acoustic foam layer and heavy layer, as well as to a method for manufacturing the cladding element.
US09598026B2 Apparatus for clamping door trim of vehicle
An apparatus for clamping a door trim of a vehicle may include a plurality of clamping portions that are installed on a door trim side and include hooks caught by a door panel side while rotating by tension of a wire, a locking portion that is installed on the door trim side and pulls the wire using a rotating pulley, and the wire that is in a closed loop form between the hooks of the plurality of the clamping portions and the pulley of the locking portion and rotates the hooks while being pulled by the rotation of the pulley.
US09598024B2 Tailgate retrieval tool and storage compartment
An apparatus comprises a mounting bracket configured to mount to a surface of a body panel of a vehicle, adjacent to an opening in the body panel. A latch mechanism is coupled to the mounting bracket. An elongate member comprising a body and a coupling mechanism is configured to couple to the latch mechanism so that, when secured, at least a portion of the body of the elongate member is positioned within an inside cavity of the body panel of the vehicle. In an embodiment, the body panel is a truck tailgate and the elongate member is a retrieval hook.
US09598021B2 Vehicle seat holster mount
A Vehicle Seat Holster Mount is presented that includes a strap mount which is the main mounting component. The upper cinch strap wraps around the seat belt receptacle. The clamp head is connected to the holster rail that is encompassed by a grip sleeve that is compressed into the space between the seats and consoles to hold the holster and/or items in place.
US09598020B2 Rear assembly for a motor vehicle and associated motor vehicle
The rear assembly (10; 110; 150) according to the invention comprises at least one lateral lining (18), intended to laterally delimit a motor vehicle trunk (12).It comprises a mechanism (22) for guiding the rotation of a tray (20) for supporting objects around a transverse axis (A-A′), relative to the lateral lining (18).For each lateral lining (18), the guide mechanism (22) comprises an insertion member (60) for at least one edge (42, 46) of the tray, the insertion member (60) being rotatably mounted around the transverse axis (A-A′) on the lateral lining (18).
US09598019B2 Variable deflector apparatus for side step of vehicle
A variable deflector apparatus for a side step of a vehicle may include a drive device, a side deflector operated by power transmitted from the drive device, the side deflector configured to be received in the side step when the side deflector is not deployed and to be perpendicularly drawn out downwards from the side step when the side deflector is deployed, thus improving aerodynamic performance of the vehicle, and a front deflector connecting a front end of the side step with a front end of the side deflector, the front deflector being kept folded when the side deflector is not deployed and configured to be unfolded to cover a lower portion of the front end of the side step when the side deflector is deployed, thus improving the aerodynamic performance of the vehicle.
US09598017B2 Teardrop shaped vehicular mirror
A vehicle mirror assembly having a housing and dome-type mirror lens. The lens has a first base footprint portion with a constant radius of curvature and a diameter, and a second base footprint portion comprised of an elliptical portion with a base major axis and a base minor axis. The mirror lens includes a first surface portion having a first surface radius and conforming to the first base footprint portion. The lens additionally includes a second surface portion conforming to the second base footprint portion. The second surface portion is comprised of a second surface major radius of curvature corresponding to a major surface axis and a second surface minor radius of curvature corresponding to a minor surface axis.
US09598013B2 Device and method for displaying head-up display (HUD) information
Disclosed herein is a device and method for displaying head-up display (HUD) information, including: a first sensing unit for detecting a surrounding brightness around a vehicle; a second sensing unit for detecting a background brightness of a background area in which the HUD information is displayed; and a control unit for comparing the surrounding brightness with the background brightness, and adjusting a brightness of the HUD information based on the background brightness when a brightness difference between the surrounding brightness and the background brightness is equal to or more than a predetermined reference value.
US09598009B2 Vehicle intersection warning system and method with false alarm suppression
A method for providing information to a driver of a vehicle includes receiving remote vehicle information indicating geospatial state and kinematic state for each of the one or more remote vehicles. The method also includes identifying host vehicle information indicating geospatial state and kinematic state for the host vehicle, identifying a queue length representing a number of vehicles queued ahead of the host vehicle, and identifying at least one of the one or more remote vehicles as a conflicting vehicle. The method also includes determining a time-to-contact based on the remote vehicle information corresponding to the conflicting vehicle and the host vehicle information. The method also includes causing a warning alert to be output if the time-to-contact is less than a warning alert threshold and only if the queue length is zero vehicles.
US09598005B2 Turn signal control apparatus and method of controlling turn signal
A turn signal control apparatus includes a switch, a flashing cycle control device, an operation device, a sharp deceleration-detection device, a bypass device, and a flashing cycle modification device. The flashing cycle control device is to determine a flashing cycle. The operation device is to open and close the switch according to the flashing cycle determined by the flashing cycle control device so that a turn signal lamp flashes. The flashing cycle modification device is to modify the flashing cycle determined by the flashing cycle control device to produce a modified flashing cycle according to a sharp deceleration-detection signal. The flashing cycle modification device and the bypass device are configured to operate to electrically connect an upstream side of the operation device and a downstream side of the operation device according to the modified flashing cycle in a case where the sharp deceleration-detection signal is outputted.
US09598000B2 Vehicle lamp system
A vehicle lamp system includes a camera which generates image information in a front region, a controller which generates a light distribution command for instructing a light distribution pattern based on the image information, a headlight which irradiates the front region such that the instructed light distribution pattern is obtained, and a position calibrator which detects a positional deviation between the camera and the headlight. The position calibrator detects a reference object based on the image information and measures a luminance of the reference object, and when there is a certain difference between a luminance of the reference object obtained from one light distribution pattern and a luminance of the reference object obtained from another light distribution pattern in which a light quantity of only a part is different from the one light distribution pattern, detects the positional deviation using a position of the part.
US09597999B2 Method for controlling a light distribution of a headlamp and headlamp therefor
The invention relates to a method for controlling a light distribution of a headlamp, wherein the headlamp has at least one light-emitting element, wherein the at least one light-emitting element is individually drivable in order to generate an individual luminous flux, wherein the light emitted by the at least one light-emitting element has a light distribution, wherein the light distribution is defined by means of a predefined, three-dimensional basic distribution on the basis of parameters, wherein an adapted light distribution is varied on the basis of the basic distribution using selected, changed parameters.
US09597992B2 Vehicle beverage holder
A vehicle center console holder for a vehicle that temporarily holds and continuously adjusts the orientation of a beverage container filled with a consumable liquid that prevents spills and allows easy removal and placement into the holder as the vehicle is moving. The holder includes a base with an upper hole with a smooth perimeter edge and a suspended beverage container vessel that fits into the upper hole and rests against the perimeter edge. The container vessel includes a downward extending, half-spherical upper member and a lower neck. Formed inside the container vessel is a center bore that receives a complimentary shaped beverage container. The upper member and the perimeter edge on the base are configured to form a gripping space between the beverage container and the upper member. When the vessel's lower neck is placed inside the upper hole, the base's perimeter edge simultaneously supports the upper member and allows the vessel to swivel freely when a beverage container is placed in the vessel.
US09597990B2 Internal map pocket
A vehicle seating assembly includes a seatback defining a cavity generally accessible via a slot disposed on a back panel of the seatback. A plurality of cover members extend over the cavity and operate between a flexed position and an unflexed position. The plurality of cover members are substantially flush with a planar portion of the back panel in the unflexed position. An elastic member is disposed on an inner-surface of the back panel proximate the plurality of cover members. The elastic member and the cover members define a pocket. The elastic member is configured to expand into the cavity, thereby expanding the pocket.
US09597989B2 Conveyance seat
A conveyance seat includes a seat frame, and a rod that extends to a region on a seat inside, and that is connected to the seat frame. The rod is connected to the seat frame via a shaft member. The shaft member includes a tubular portion having a through-hole, and a protruding portion protruding toward an outside in a radial direction from one end of the tubular portion in an axial direction. The shaft member is assembled to the seat frame in a state in which the tubular portion is inserted through the seat frame from a seat outside, and an insertion position of the shaft member in the axial direction is restricted by a position where the protruding portion abuts against an outside surface of the seat frame. The rod is inserted in the axial direction through the through-hole in the shaft member, and assembled to the shaft member.
US09597987B2 Vehicle seat
A rear end portion of a cushion cover that covers a surface of a seat cushion in a rear end portion thereof is provided with a hook that clips the rear end portion of the cushion cover at a frame wire of the seat cushion, and that is formed with a clip mounting hole for mounting a clip. The clip is mounted to the hook by the clip mounting hole, and an electric wiring is held by the clip.
US09597979B1 Method of controlling regeneration and boost functions of a hybrid powertrain
A method of controlling a powertrain of a hybrid vehicle includes comparing an operating efficiency of a motor-generator-inverter to an upper MGI efficiency threshold when a boost operating mode is selected. When the operating efficiency of the motor-generator-inverter is equal to or greater than the upper MGI efficiency threshold, the motor-generator-inverter is controlled to operate in the boost operating mode. The operating efficiency of the motor-generator-inverter is compared to a lower MGI efficiency threshold when a regenerative operating mode is selected. When the operating efficiency of the motor-generator-inverter is equal to or greater than the lower MGI efficiency threshold, the motor-generator-inverter is controlled to operate in the regenerative operating mode.
US09597978B1 Hovering skate board unit and method thereof
A hovering skate board unit capable of driven by a user is disclosed. The hovering skateboard includes a first board to receive the user, one or more first magnetic source, a second board magnetically coupled with the first board, one or more second magnetic source and at least one ground engaging wheel. The first magnetic source is configured with the first board to emit magnetic field. The one or more second magnetic source is configured with the second board to repel the magnetic field emitted from the one or more first magnetic source and further facilitates the first board to hover over the second board. The ground engaging wheels attached to the second board moves in the direction driven by the user. Further, a corresponding method of operating the hovering skate board unit is also disclosed.
US09597974B2 Network-controlled charging system for electric vehicles
A server of a network-controlled charging system for electric vehicles receives a request for charge transfer for an electric vehicle at a network-controlled charge transfer device, determines whether to enable charge transfer, and responsive to determining to enable charge transfer, transmits a communication to the network-controlled charge transfer device that indicates to the network-controlled charge transfer device to enable charge transfer.
US09597971B2 Methods and systems for compatible operation between a wireless power transfer system and vehicle remote entry systems
Methods and apparatuses for transmitting charging power wirelessly are provided. One implementation includes an apparatus for transmitting charging power wirelessly to a vehicle. The apparatus comprises a transmit circuit configured to transfer wireless charging power to the vehicle via a wireless field. The apparatus comprises a controller configured to detect transmission of a wireless vehicle signal having a transmission period and indicative of operation of a vehicle communication system. The controller is configured to cause the transmit circuit to reduce a level of charging power within a first portion of the transmission period. A second, remaining portion of the transmission period is of sufficient duration for allowing identification of the wireless vehicle signal by a receiver of the wireless vehicle signal. The wireless vehicle signal comprises a plurality of pulses. At least one pulse is transmitted within the first portion. The remaining pulses are transmitted within the second, remaining portion.
US09597969B2 Systems and methods for providing in-road electric conductivity boxes and on-vehicle descent and pivot contacts for vehicles
Systems and methods for providing in-road electric conductivity boxes and on-vehicle descent and pivot contacts for vehicles are provided. In one example embodiment, a system includes, inter alia, a charging component physically coupled to a roadway, a power source electrically coupled to the charging component, and a vehicle that electrically couples with the charging component for receiving power from the power source via the charging component when the vehicle is on the roadway at a location proximate to the charging component. Additional embodiments are also provided.
US09597967B2 Status indicating electric vehicle charging station, lightguide assembly and methods
An electric vehicle charging apparatus is disclosed. The electric vehicle charging apparatus has a housing having a body, and a light guide assembly adapted to display a status of the electric vehicle charging apparatus. The light guide assembly generates and displays one or more colors, flashing lights, or combinations thereof on a light exit region of the light guide. In another aspect, a locking hinged lid configuration of the electric vehicle charging apparatus is provided. In yet another aspect, a mechanical control panel including lighted status indicators on the lid is provided. In another aspect, the electric vehicle charging apparatus has one or more low voltage terminals contained in a first front cavity under the lid, whereas high voltage components are provided in a separate second front cavity. Methods of operating the electric vehicle charging apparatus are provided, as are other aspects.
US09597961B2 Wading vehicle water level display
A vehicle (100) comprising a wading information display (1020) and a wading depth sensor, the display showing an elevation of a vehicle on which is superimposed the current wading depth. The display may also indicate simultaneously the maximum wading depth calculated according to the ride height of the vehicle, the inclination of the vehicle by inclination of the displayed elevation, and an advisory speed according to wading depth and/or vehicle inclination.
US09597960B2 Driving assistance device
In a driving assistance device 1, when an execution determination unit 12 determines that a driving assistance unit 11 performs driving assistance, a consciousness degradation determination unit 13 performs control such that a warning unit 9 is less likely to issue a warning than that when the driving assistance is not performed. Therefore, even when the position of a host vehicle is changed by the steering of the host vehicle by a driving assistance unit 11, it is possible to reduce the discomfort of a driver due to a warning.
US09597956B2 Vehicle roof structure and vehicle, and method of manufacturing vehicle roof unit
A vehicle roof structure includes a solar cell unit including a plurality of solar cells arranged in a planar form, a plate-like roof panel made of a resin having transparency and disposed to cover the solar cell unit from above, and a plurality of reinforcements each being implemented by a metallic member and disposed to support the solar cell unit from below and to extend in a vehicle longitudinal direction and/or a vehicle width direction. The vehicle roof can be reduced in weight.
US09597954B2 Exhaust support system for an off-road vehicle
An exhaust support system for an off-road vehicle including a fender having a liquid storage tank, a loading plate coupled to a frame of the off-road vehicle, and a gusset coupled to the liquid storage tank and to the loading plate. The gusset is formed from a flat plate and includes a body coupled to the liquid storage tank, a base coupled to the loading plate, and a curved portion coupling the base to the body. Additionally, the curved portion is configured to redistribute a force from the liquid storage tank to the loading plate.
US09597949B2 Glass run for automobile
A glass run that is excellent in appearance quality and durability, and exhibits improved sealing properties is proposed. The glass run for attachment to vertical sides of the door frame has a bottom wall for attachment to a door frame or a door molding, and an outer seal lip extending from an exterior side edge of the bottom wall. The outer seal lip has a base part extending towards a door glass, and a main part extending from the base part while curving inwardly of the base part. When the outer seal lip is deformed and bent with a side edge of the door glass, a tip end part of the outer seal lip is located inwardly of a surface of the bottom wall or the outer side wall, which faces a side edge of the door glass, and the base part is formed to have a rigidity lower than that of the main part.
US09597945B2 Automotive HVAC system with suction surfaces to control local airflow
An HVAC system provides airflow in a vehicle having a plurality of seating locations in a passenger cabin for respective passengers of the vehicle. The system includes a plurality of outlet vents and a plurality of suction returns disposed at various air return locations adjacent to the seating locations within the vehicle. An air handling unit is in fluid communication between the suction returns and the outlet vents. A plurality of flow control elements are provided, each one in series with at least one respective suction return for selectably modifying a respective flow of the respective suction return in response to a respective flow command. An occupancy determining apparatus identifies one or more seating locations for receiving enhanced airflow. A controller generates the respective flow commands in response to the identified seating locations.
US09597943B2 Swing arc HVAC duct
A duct for a heating/ventilation/air conditioning system of a vehicle includes a first end and a second end spaced a distance from the first end. An orifice extends between the first end and the second end. A semi-circular surface is disposed at the second end. The semi-circular surface extends about a radius having the same length as the distance between the first and second ends.
US09597942B2 Rotational damper for a motor vehicle
A rotational damper for a motor vehicle, includes a gyro element which includes a first shaft mounted such that it can be rotated with respect to a first component and is connected to a second component which performs a relative movement with respect to the first component, wherein the first shaft has a frame, in which a second shaft lies orthogonally and is mounted rotatably, wherein the second shaft has a frame, in which a third shaft is mounted orthogonally with respect to the second shaft and such that it can be rotated in the second frame, wherein the second shaft and the third shaft are each connected to a shaft drive, and the third shaft has an inertia weight, wherein a rotation of the second shaft by the second shaft drive brings about a change in the angular velocity or the moment of the first shaft which is connected to the second component.
US09597933B2 Micro electro mechanical system, semiconductor device, and manufacturing method thereof
The present invention provides a MEMS and a sensor having the MEMS which can be formed without a process of etching a sacrifice layer. The MEMS and the sensor having the MEMS are formed by forming an interspace using a spacer layer. In the MEMS in which an interspace is formed using a spacer layer, a process for forming a sacrifice layer and an etching process of the sacrifice layer are not required. As a result, there is no restriction on the etching time, and thus the yield can be improved.
US09597932B2 Tire-pressure adjusting device for a tire inflation system of a vehicle
A tire-pressure adjusting device for a vehicle tire inflation system distributes a compressed-air supply to a plurality of pneumatic apparatuses each comprising a rotary transmitter and measures the tire pressures of vehicle tires connected to the rotary transmitters. The tire-pressure adjusting device includes a control apparatus for receiving a pressure measurement signal and for outputting control signals and a modulation valve apparatus for receiving the control signals and for pneumatically activating one of a plurality of connected rotary transmitters in order to fill and to measure the pressure of at least one vehicle tire connected to the rotary transmitter. The modulation valve apparatus includes a rotary valve, which has a control element that can be rotated into a plurality of rotational positions. The control element activates one of the plurality of pneumatic apparatuses in each of the rotational positions of the control element.
US09597929B2 Tire
Stepped sections (110) whereby the height of a block (100) gradually decreases towards the outside of the tire peripheral direction from the center of the block (100) are formed in a peripheral direction end section (160) of the block (100). The stepped sections (110) have a first stepped surface (111a) and a second stepped surface (121a). A stepped surface (110a) extends from an outside end section (140) towards an inside end section (150).
US09597920B2 Writing instrument or applicator having resin molded parts
Provided is a writing instrument or an applicator using resin parts formed, by way of two-color molding, to have an optimal guiding clearance between slide members. A plurality of resin molded parts is included. At least one of the plurality of resin molded parts is formed as a primary molding, and at least another one of the resin molded parts is formed as a secondary molding, by way of two-color molding, using a portion of a surface of the primary molding. The primary molding and the secondary molding are separated to be used as independent members. In this case, the primary molding and the secondary molding are preferably configured to slide against each other by each separating portion.
US09597915B2 Adhesive applicator
Bookbinding apparatus adhesive applicator accurately, briefly controls adhesive temperature to a set value by selecting, in accordance with adhesive initial temperature, one of a plurality of temperature-controller heating modes defining different supply powers and supply durations for supplying power to an adhesive-container heater to control its heating temperature. A sensor detects the temperature of the adhesive in the container at applicator start-up, or on restarting a post-standby applicator. In accordance with the detected temperature, one of the heating modes is selected to heat the adhesive. The applicator warm-up time is thus set in response to the state of the adhesive: If solidified, the adhesive is heated and melted in a maximum supply-power, supply-duration mode; if low-temperature liquefied, it is heated and melted in a second-magnitude supply-power, supply-duration mode; and if the adhesive temperature is high, it is heated and melted in a minimal supply-power, supply-duration mode.
US09597914B2 Ink jet recording method and ink jet recording apparatus
An ink jet recording method includes forming an under layer by applying an active energy ray curable first ink composition which contains a metallic pigment to a printing medium, forming an intermediate layer by applying an active energy ray curable second ink composition to the under layer, and forming a first image by applying the first ink composition to the intermediate layer. In addition, it is possible to include irradiating of active energy rays onto the under layer before the forming of the intermediate layer, irradiating of active energy rays onto the intermediate layer before the forming of the first image, and irradiating of active energy rays onto the first image after the forming of the first image.
US09597913B2 Image receiving material for offset printing
The invention relates to an image receiving material for offset printing comprising a support and an image receiving layer, the image receiving layer comprising a porous pigment and an aqueous dispersion of a polymer particle characterized in that the image receiving layer further comprises a copolymer comprising alkylene and vinyl alcohol units.
US09597912B2 Composition for protection layer and thermal recording material
A composition for a protection layer of a thermal recording material includes emulsion (A) and non-crosslinkable urea compound (B), and emulsion (A) has a pH of 6 or more, and contains copolymer resin (a) produced by copolymerizing reactive monomer component (a′) containing at least a vinyl monomer component having a carboxyl group and a vinyl monomer component that is copolymerizable with the vinyl monomer component having a carboxyl group.
US09597908B2 Printer displays heating elements status and sets a check range to determine whether the heating elements is normal or abnormal
A printer includes a printing portion, a display, and a processor. The printing portion includes a plurality of heating elements arrayed in a specified direction. The printing portion is configured to perform printing on a print medium. The display is configured to display an image. The processor is configured to cause the display to display a first image, the first image being an image that shows the plurality of heating elements, receive specification of a check range, the check range being a range that includes a heating element to be checked among the plurality of heating elements, check, in a case where the specification of the check range is received, a state of the heating element included in the check range, and cause the display to display a check result of the state of the heating element.
US09597906B2 Print device
A print device includes a housing, a lid body, an input device, and a mounting portion. An opening is formed in an upper portion of the housing. The lid body opens and closes the opening of the housing by a second end portion side of the lid body pivoting around a predetermined rotation axis provided at a first end portion of the lid body. The mounting portion is provided on an upper portion of the lid body when the opening is closed. The input device can be attached to and detached from the mounting portion along a predetermined attachment/detachment direction with respect to the lid body. The attachment/detachment direction is orthogonal to an extending direction of a tangent line. The tangent line is tangential to a circumferential direction of the rotation axis at a position of the second end portion of the lid body.
US09597904B2 Droplets ejecting apparatus
A droplets ejecting apparatus includes: an ejection head that ejects droplets to a predetermined ejection direction toward a recording medium being fed in a predetermined feeding direction; a support unit that supports the ejection head; moving members that are provided for a first-side portion and a second-side portion between which an ejection region of the ejection head is interposed in the feeding direction in a view as viewed in the ejection direction, and that move the first-side portion and the second-side portion in a crossing direction that is perpendicular to the ejection direction and the feeding direction; and a control unit as defined herein.
US09597903B1 Printer
A printer is for accommodating paper roll and includes main body, cover, first printing set and detecting module. The main body has an accommodating space and a shaft located in the accommodating space. The cover is pivoted to the main body. The first printing set is disposed in the main body. The detecting module includes a switch and a flexible member being disposed close to the switch and having a fixed section and a movable section which are opposite to each other. The movable section is movably located between the paper inlet and the paper roll. When the movable section is pressed by the paper sheet and moved toward the switch, the movable section presses against the switch. When the movable section of the flexible member is not being pressed by the paper sheet, the movable section is located in a first detecting area.
US09597902B2 Printer
In a printer including a reflection type optical sensor and a transmission type optical sensor arranged to oppose each other across a paper conveyance path, a sensor spring and a plate spring are elastically deformed consequent to the wave shape of a guide unit and a guide unit, according to the positions of the reflection type optical sensor and the transmission type optical sensor along the width direction of the printer, enabling the reflection type optical sensor and the transmission type optical sensor to be moved based on the pitch of the wave shape along the width direction of the printer while transmitting a click feeling to an operator each time the sensor spring and the plate spring climb over a protruding portion of the wave shape.
US09597899B2 Information processing apparatus, program, information processing method, printing apparatus, and printing system
The present invention provides an information processing apparatus. The apparatus includes a generating unit generating printing data for printing on a printing medium by a printing apparatus, an analyzing unit analyzing a margin amount on a leading edge side of the printing medium based on the printing data, and a transmitting unit transmitting margin information based on an analysis result of the analyzing unit to the printing apparatus prior to transmission of the printing data to the printing apparatus.
US09597897B2 Printing apparatus with user interface for setting operable tray
A printing apparatus includes: a paper cassette that includes a plurality of trays, each of which holds a printing medium, and a switching unit that sets one of the plurality of trays as an operable tray; a printing unit that performs printing on the printing medium held in the operable tray; and a display control unit that causes a user interface, on which setting of which one of the plurality of trays is set as the operable tray by the switching unit is performed by a user, to be displayed on a screen when the paper cassette is set in the printing unit.
US09597894B2 Thermal printer
An apparatus for determining the resistance of a printing element of a print head, the apparatus comprising: a print head comprising a plurality of individually controllable printing elements connected in parallel, and a capacitor connected in parallel with the printing elements; a test voltage supply arranged to supply a test voltage to the print head; a current monitor arranged to measure the current supplied to one of the printing elements when the said one of the printing elements is connected to the test voltage supply; and a controller arranged to determine the resistance of the said one of the printing elements based upon the measured current.
US09597893B2 Element substrate and liquid discharge head
If the shape of an element substrate is a parallelogram, a trapezoid, an uneven shape, or the like, there is no region where a driver transistor corresponding to a heater in the vicinity of an end portion of the element substrate is arranged, and thus the heater cannot be arranged near the end portion. The layout arrangement of driving circuits suitable for the substrate shape is required while suppressing an increase in the area of the element substrate. In an embodiment of this invention, the diffusion layer of the drain electrode of a driver transistor for driving a heater is divided in a direction perpendicular to that in which heaters are arranged, and the divided portions are connected to form one driver transistor. The divided portions are arranged stepwise.
US09597892B2 Inkjet printing method and inkjet printing apparatus
The present invention provides an inkjet printing method using an inkjet printing apparatus, the method including: Control the print heads in the first row of the first group on carriage to print the first color printing image on the transparent media. Control the first nozzle section on print heads in the second row of the second group on carriage to print the first white ink layer on the first color printing image. Control the second nozzle section on black ink print head in the second row of the first group on carriage to jet black ink to form coating layer on the first white ink layer. Control the third nozzle section on print heads in the second row of the second group on carriage to print the second white ink layer on the said coating layer. Control the print heads in the third row of the first group on carriage print the second color printing image on the second white ink layer. The print heads are arranged in three rows in this invention. The print heads in the second row are divided into three nozzle sections. With a single direction transport of the transparent media rather than back and forth transport, double sides images can be formed through five layers printing on the transparent media by controlling three nozzle sections on black and white ink print head in the second row.
US09597891B2 Inkjet ink, method of manufacturing inkjet ink, ink cartridge, and inkjet recording device
An inkjet ink contains water, a hydrosoluble organic solvent, a pigment, polyvinyl pyrolidone, and a copolymer, wherein the copolymer contains a structure unit represented by Chemical formula 1, where R1 represents a hydrogen atom or a methyl group, R2 is an alkyl group having one to four carbon atoms, M1+, M2+, M3+, and M4+ each, independently represent protons, alkali metal ions, or organic ammonium ions, and a structure unit represented by Chemical formula 2, where R3 represents a hydrogen atom or a methyl group, a structure unit represented by Chemical formula 3, where R4 represents a hydrogen atom or a methyl group, or a structure unit represented by Chemical formula 4, where R5 represents a hydrogen atom or a methyl group.
US09597886B2 Printer ink cartridges
A printer cartridge is disclosed that is under negative pressure to retain liquid and allows controlled ingress of atmospheric air to release liquid from the printer cartridge. A labyrinth on a surface of the printer ink cartridge provides controlled ingress of atmospheric air having an entrance chamber to allow entry of atmospheric air, an exit chamber in communication with the liquid, and an elongate channel extending between the entrance chamber and the exit chamber. The elongate channel having a raised track formed on the surface and extending along each side of the elongate channel.
US09597885B2 Ink cartridge
An ink cartridge comprises a main body comprising a first surface, a second surface, and a chamber, configured to store ink, disposed between the first surface and the second surface; an ink outlet portion disposed on the first surface of the main body configured to direct the ink from the chamber to an exterior of the main body; and an electronic circuit board disposed on the main body. The electronic circuit board comprises an electrical interface, a first portion facing a second direction that intersects a first plane that is perpendicular to the first direction, a second portion facing a third direction away from the ink outlet portion that intersects a second plane that is parallel to the first direction, and a connecting portion between the first portion and the second portion. The electrical interface is disposed on an area of the electronic circuit board including the connecting portion.
US09597876B2 Ink-jet recording apparatus and accumulation suppressing method
There is provide an ink-jet recording apparatus including: an ink containing a self-dispersible pigment; an ink-jet head configured to discharge the ink; an absorber which is arranged in an area facing a discharge surface of the ink-jet head, and which is configured to absorb the ink discharged from the ink-jet head; and a liquid agent which contains a water-soluble organic solvent, and which is absorbed in the absorber, wherein a surface tension of an aqueous solution containing the liquid agent at concentration of 5% by weight is not more than 50 mN/m; and a blending percentage by weight of the water-soluble organic solvent in the liquid agent is not less than five times a blending percentage by weight of the self-dispersible pigment in the ink.
US09597872B2 Droplet discharge head and image forming apparatus incorporating same
A droplet discharge head includes a nozzle, a substrate, a diaphragm, and an electromechanical transducer element. The nozzle discharges droplets. The substrate includes a pressurization chamber communicated with the nozzle. The diaphragm is disposed on the substrate. The electromechanical transducer element is disposed on the diaphragm. The electromechanical transducer element includes an electromechanical transducer film, a lower electrode, and an upper electrode. The electromechanical transducer film includes a piezoelectric material. The lower electrode is disposed below the electromechanical transducer film, to apply voltage to the electromechanical transducer film. The upper electrode is disposed above the electromechanical transducer film, to apply voltage to the electromechanical transducer film. The diaphragm includes an SiO2 film, an SiN film, and a Poly-Si film laminated one on another. The diaphragm has, in a direction of lamination, a thickness of not less than 1 μm and not greater than 3 μm. The diaphragm has a deflection projecting toward the pressurization chamber with no voltage applied to the electromechanical transducer film. A radius of curvature of the deflection in a transverse direction of the diaphragm is in a range of not less than 2000 μm and not greater than 6000 μm.
US09597871B2 Base, liquid discharge head, printing apparatus, and method for determining liquid discharge status
An embodiment of this invention is directed to determining a discharge status of liquid discharged from a liquid discharge head capable of accurately determining the discharge status of each nozzle at high speed with a simple arrangement. According to the embodiment, a base includes an electrothermal transducer configured to supply heat to liquid, a first temperature detection element configured to detect the temperature of the electrothermal transducer, and a second temperature detection element configured to detect the temperature of the same electrothermal transducer. In this case, the first and the second temperature detection elements are arranged so that at least part of each of the first and second temperature detection elements is included immediately above or below a region where the electrothermal transducer is arranged in the base.
US09597867B2 Digital printed duct tape
A duct tape and a method of making a duct tape having a customized, printed design on a surface of the duct tape. The method comprises providing a design for printing on the duct tape, digitally printing the design on the surface of the duct tape, and curing the ink printed on the duct tape with ultraviolet light in dual stages. The method further comprises applying on the digitally printed duct tape a material or composition having overcoat properties, release properties, or a combination thereof.
US09597863B2 Adhesive sheet material application device and method
According to one aspect of the present invention, an adhesive sheet material application device is disclosed, which includes a roller support bar, a handle, and a roller, where the handle and the roller are connected to the roller support bar, a portion of the handle is parallel to the roller, and the roller is rotatable. In another aspect of the present invention, a second handle is connected to the roller support bar and the second handle has a strap. According to another aspect of the present invention, a method of using the adhesive sheet material application device is disclosed, which includes securing a portion of adhesive sheet material to a surface, applying the adhesive sheet material to the surface with the adhesive sheet material application device, and regressing and eradicating bubbles between the adhesive sheet material and surface.
US09597860B2 Container with high moisture barrier properties and a reclosable pour spout
A paperboard substrate that can be used to provide a food packaging particle is provided having a water vapor barrier layer comprising HDPE in combination with a nucleating agent which is extruded on to a paperboard substrate. The resulting substrate has sufficiently good water vapor barrier when properties that dry foods such as cereals do not require a bag or inner liner as a separate moisture barrier.
US09597858B2 Method for manufacturing touch panel and molded article
An object of the present invention is to provide a method for manufacturing a touch panel. A laminated film is used. The laminated film comprises a resin layer, a protection film-constituent material layer provided on a surface of the resin layer, and a releasing layer provided on a surface of the protection film-constituent material layer. The protection film-constituent material layer is a layer containing fluorine-based substances. The releasing layer is a layer made by using a fluorine-based resin. The method comprises a molding process, a hardening treatment process for providing hardening treatment to the protection film-constituent material layer after the molding process, and a removal process for removing the releasing layer after the molding process. The protection film-constituent material layer is an uncured layer in the course of a molding process.
US09597854B2 Resin laminated plate
Provided is a resin laminates in which the depth of concave ribs provided to a back side sheet can be made uniform, even when a convex region and flat regions are present on an front side sheet of the resin laminate. The resin laminate is provided with the front side sheet and the back side sheet, which overlap with a hollow interposed therebetween. The back side sheet is recessed into the hollow, and a large number of concave ribs are provided. The bottoms of the concave ribs are fused to the front side sheet. The front side sheet is provided with front side flat region configured from a flat surface and a front side convex region protruding away from the hollow. The back side sheet is provided with back side flat region configured from a flat surface and a back side concave region recessed into the hollow.
US09597850B2 Alignment of plunger with gearbox in a baler
A system and method for aligning a compacting plunger of an agricultural square baler with respect to a gearbox for driving the compacting plunger. The method includes controlling a position of plunger rails on and against which the compacting plunger will move when the agricultural square baler is in operation, with respect to a position of a carrying beam adapted for carrying the gearbox. Controlling the position of the plunger rails with respect to the carrying beam adapted for carrying the gearbox rather than with respect to the side walls of the baler provides the advantage of reduced wearing and/or fractures of parts of the baler.
US09597849B2 Mold for tire having a removable annular insert
A mold for vulcanizing and molding a tire, the tire having a tread delimited by two sidewalls, at least one of which is provided with a complex protuberance, the mold having a ring for molding the tread of the tire and two shells for molding the sidewalls, the mold having an annular insert that separates the mold into at least two portions, namely a ring portion and a shell portion in the radially lower region of the sidewalls, the insert having two adjacent concentric elements that are intended to mold the complex protuberance, namely a radially outer element associated with the ring, and a radially inner element associated with the shell.
US09597848B1 Method and system for forming a self-sealing volume
A method and system for forming a self-sealing volume includes an elastomeric composite structure. The structure includes layers of a cast polyurethane derived from a neat polyurethane monomer reaction mixture that does not substantially react at room temperature. The polyurethane monomer reaction layer includes a reaction product of an organic polyisocyanate and a reactive hydrogen-containing material reacted with a mixture of a monomeric polyol and polymeric polyols. The structure may further include one or more layers of a fabric that have been precoated with an aliphatic polyurethane, and one or more sealing layers. A fuel impermeable inner liner may be positioned in an inner region. The sealing layers may comprise at least one of partially vulcanized natural rubber (NR), polyisoprene (IR), styrene butadiene (SBR), or a blend of SBR with NR or IR. A dimensionally correct, self-sealing volume may be created by inflating the volume during its cure.
US09597847B2 Method and apparatus for inserting a spacer between annular reinforcement bands
A method is provided for making an annular reinforcement structure having inner and outer reinforcement bands maintained in concentric alignment by a resilient spacing element positioned between the bands. The method includes the steps of placing the spacing element against the inside face of the outer reinforcement band and compressing the spacing element with a jig, adjacent the top edge of the outer reinforcement band. The spacing element is sufficiently compressed to allow the inner reinforcement band to slide into concentric alignment with the outer reinforcement band, with a minimum of deflection and/or distortion of the inner reinforcement band.
US09597836B2 Method for manufacturing three-dimensional shaped object
There is provided a manufacturing method of the three-dimensional shaped object, the method being capable of suitably reducing the local raised portion which can occur during the light beam irradiation under the condition of the divided sub-irradiation paths. The manufacturing method of the present invention is performed by repetition of a powder-layer forming and a solidified-layer forming, wherein an irradiation path of the light beam is divided into a plurality of sub-irradiation paths including a short sub-irradiation path with its length being shorter than a predetermined length and a long sub-irradiation path with its length being the predetermined length or longer, and wherein an irradiation mode of the light beam is changed depending on the lengths of the sub-irradiation paths.
US09597834B2 Electrochemical fabrication method including elastic joining of structures
Forming multi-layer 3D structures involving the joining of at least two structural elements, at least one of which is formed as a multi-layer 3D structure, wherein the joining occurs via one of: (1) elastic deformation and elastic recovery, (2) relative deformation of an initial portion of at least one element relative to another portion of the at least one element until the at least two elements are in a desired retention position after which the deformation is reduced or eliminated, or (3) moving a retention region of one element into the retention region of the other element, without deformation of either element, along a path including a loading region of the other element and wherein during normal use the first and second elements are configured relative to one another so that the loading region of the second element is not accessible to the retention region of the first element.
US09597831B2 Blow molding tooling for high cavitation applications
An injection station of an injection blow molding machine and a method for forming parisons and molded articles. The injection station includes a die plate with a keyway formed through a least a portion of a surface of the die plate. The keyway separates front and back portions of the surface of the die plate. The injection station further includes a resin injection tooling comprising a draw bar, with at least a portion of the draw bar operable to be positioned within the keyway of the die plate, a base plate secured to a back side of the draw bar and operable to be secured to the back portion of the surface of the die plate and, and a manifold secured to a top of the base plate, with the manifold being configured to discharge resin into cavities to form the parisons.
US09597827B2 Mold clamping force setting device and mold clamping force setting method of injection molding machine
A distortion sensor is provided on each of a plurality of tie bars and the extension amount of each tie bar is detected by the distortion sensor thereof, whereby a mold clamping force actually applied to a mold is measured. This measurement specifies the part of the mold that first opens and obtains a minimum mold clamping force that does not open the mold in that part. The minimum mold clamping force thus obtained is the minimum mold clamping force that does not open the mold without being influenced by factors such as the shape and the arrangement of a cavity in the mold and the mold clamping force balance of a mold clamping part of an injection molding machine.
US09597826B2 Method of repairing, splicing, joining, machining, and stabilizing honeycomb core using pourable structural foam and a structure incorporating the same
A method of the present disclosure includes of repairing a core stiffened structure with structural foam. Another method includes splicing core members together using structural foam. Another method includes joining a core member to a structure using structural foam. Another method includes using structural foam to stabilize a core member during a machining process. Another method includes stabilizing a core member with structural foam to prevent the core member from crushing in autoclave pressure. The present disclosure further includes a core stiffened structure have a core member with structural foam therein.
US09597815B2 Food comminution device
The invention relates to a food comminution device having a base part, which bears a cutting part, and having an actuation part, which actuation part is articulatedly fixed to the base part and can be pivoted from a loading position toward the cutting part into a closed position in order to push food items for comminution through the cutting part and can subsequently be pivoted from the closed position into the loading position again. The food comminution device is characterized in that the base part has the outer contour of a cuboid as its outer contour, and in that the food comminution device has a collecting container, and in that, on one face surface of the base part, there is provided an opening for the sliding-in of the collecting container into the base part, and in that the cutting part is arranged on a first side surface of the base part, which side surface is adjacent to the face surface, and in that the cutting part and the actuation part are constituent parts of a first comminution tool, and in that the base part is a constituent part of a further comminution tool, and/or at least one further comminution tool is fixed to the base part, wherein the further comminution tool is arranged on a further side surface of the base part, which further side surface is adjacent to the face surface, and in that the collecting container can be arranged in the base part selectively in a first position, in which said collecting container collects food items comminuted by way of the first comminution tool, or in a second position, which differs from the first position and in which said collecting container collects the food items comminuted by way of the second comminution tool.
US09597812B2 Slicing device comprising a product gripper
A slicing device includes a cutting blade, a support, an endless belt, and a gripper. The cutting blade separates slices from a front end of a food product. The endless belt conveys the food product in a direction of a cutting blade and/or presses the food product against the support. The gripper is arranged on the endless belt so that the gripper is conveyed in a direction of a rear end of the food product to grip the rear end of the food product. A position of the gripper is moveable in a direction of the support. The endless belt includes a first portion and a second portion. The first portion is arranged closer to the cutting blade than the second portion. The first portion is arranged generally parallel to the support, and the second portion is arranged at an angle relative to the first portion.
US09597805B2 Care apparatus
A care apparatus is described that has the capability to sense environmental characteristics, detect a dependent's condition, and carry out suitable actions to care for the dependent. The care apparatus may move in various directions, store items, take images, play sounds, music, and videos, and facilitate two-way wireless communication with other devices.
US09597803B2 Robot device
Provided is a small-sized robot device having high versatility without decreasing the work efficiency. The robot device includes: an arm; a hand or a tweezer tool that includes a stereo camera for measuring a three-dimensional position of a workpiece, the hand or the tweezer tool performing a work with respect to the workpiece whose three-dimensional position has been measured by the stereo camera; and a connection portion or a hand provided at a distal end of the arm, the connection portion or the hand releasably connecting the hand or the tweezer tool to the arm.
US09597798B2 Control method of robot apparatus and robot apparatus
A control method of a robot apparatus, the robot apparatus including a link and a pair of actuators, obtaining each driving force command value of each of the actuators, and controlling each of the actuators, the control method including: a torque command value calculation step of using the target stiffness, the target trajectory, angular velocity of the target trajectory, and angular acceleration of the target trajectory to calculate a torque command value; a determination step of determining whether each of the driving force command values is a value 0 or greater; a change step of performing at least one of a change of increasing the target stiffness and a change of reducing the angular acceleration; and a driving force command value calculation step of using the target stiffness and the torque command value to calculate each of the driving force command values.
US09597797B2 Apparatus and methods for haptic training of robots
Robotic devices may be trained by a trainer guiding the robot along a target trajectory using physical contact with the robot. The robot may comprise an adaptive controller configured to generate control commands based on one or more of the trainer input, sensory input, and/or performance measure. The trainer may observe task execution by the robot. Responsive to observing a discrepancy between the target behavior and the actual behavior, the trainer may provide a teaching input via a haptic action. The robot may execute the action based on a combination of the internal control signal produced by a learning process of the robot and the training input. The robot may infer the teaching input based on a comparison of a predicted state and actual state of the robot. The robot's learning process may be adjusted in accordance with the teaching input so as to reduce the discrepancy during a subsequent trial.
US09597786B2 Torque limiting tool and method for using the same
A torque limiting tool, method for using the same, and set of torque limiting tools according to different loads are arranged for adjusting a device to a predetermined load, and preventing further adjustment once the predetermined load is reached.
US09597785B1 Depth setter with a truncated distal edge portion
A depth setter for a rotary tool, includes a distal end having a centrally-located bit tip and a cylindrical collar with an edge portion extending therearound, where the edge portion includes a resilient elastomeric material extending therealong and a truncated surface extending peripherally therearound, and an attachment end for securely attaching the depth setter to the drive mechanism of the rotary tool.
US09597781B2 Assembly jig for use in assembly of large structure
An assembly jig includes an upper jig frame that is provided above a longitudinal outer edge of a large structure, a lower jig frame that is provided below a longitudinal outer edge of the large structure, a connecting jig frame that connects the upper jig frame and the lower jig frame to each other, three supporting parts for supporting the lower jig frame from below, and a jig leg portion that is provided perpendicular to the direction in which the lower jig frame extends and parallel to a ground surface. The supporting parts are provided at three portions that are respectively located under two end portions of the jig leg portion and under the lower jig frame, and arrangement positions of the supporting parts provided at the three portions form a substantially triangular shape when seen from above.
US09597779B2 Actuating device
An actuating device has an actuating element connected in a rotationally-fixed manner to a shaft. The shaft is mounted so that it is rotatable in the housing. The actuating element is pivotable using a hand lever connected to the shaft. The hand lever is formed from an attachment element connected to the shaft and an elongated handle element fastened on the attachment element. The handle element is fastenable at different positions on a front side of the attachment element. The front side of the attachment element is oriented perpendicularly to a main axial direction of the shaft.
US09597778B2 Tool for torsion bar repair
A method and tool assembly (10) for unloading and reloading spring energy from a torsion bar (11) in a torsion bar suspension system of a motor vehicle. The tool assembly (10) includes a generally C-shaped body (14) having a screw shaft (24) threaded through a boss (22) in a lower section (18) thereof. An anti-rotation stem (38) includes a knurled flat face (40) which increases versatility of the tool assembly (10) by enabling anti-slip operation with various vehicle types. A counter-torque tool perch (46) extends from the lower section (18) of the tool body (14) for applying a counter-rotational torque to the body (14) during use of the tool assembly (10).
US09597772B2 Automated determination of jet orientation parameters in three-dimensional fluid jet cutting
Methods, systems, and techniques for automatically determining jet orientation parameters to correct for potential deviations in three dimensional part cutting are provided. Example embodiments provide an Adaptive Vector Control System (AVCS), which automatically determines speeds and orientation parameters of a cutting jet to attempt to insure that a part will be cut within prescribed tolerances where possible. In one embodiment, the AVCS determines the tilt and swivel of a cutting head by mathematical predictive models that examine the cutting front for each of “m” hypothetical layers in a desired part, to better predict whether the part will be within tolerances, and to determine what corrective angles are needed to correct for deviations due to drag, radial deflection, and/or taper.
US09597766B2 Brush unit, a device for brush-polishing that uses the brush unit, a system for brush-polishing, and a method for brush-polishing
The purpose of the present invention is to provide a device for brush-polishing by means of a polishing brush that rotates and revolves as in a planetary motion, wherein the conditions to polish can be easily set in accordance with the properties of the workpiece and the purposes to polish. A brush unit has a polishing brush that rotates and revolves. The brush unit includes a mechanism for driving the rotation that rotates the polishing brush and the mechanism for driving the revolution that revolves it. By adjusting the speed of the rotation by the mechanism for driving the rotation the capabilities to polish the workpiece are enhanced. By adjusting the speed of the revolution by the mechanism for driving the revolution the entire workpiece is uniformly polished.
US09597764B2 Cutting machine with grinding unit
A cutting machine includes a circular knife and a grinding unit for grinding the circular knife, wherein the grinding unit can be adjusted to grind the circular knife at different angles.
US09597763B2 Modular wire and/or tubular component processing apparatus
An apparatus for the processing of wire and/or tubular components includes a base member and at least two wire/tube processing modules. The modules can be releasably engaged with each other and the base member in which engagement mechanically and electrically couples the modules and the base member. The base member includes an operator interface enabling operation to any linked module.
US09597762B2 Tool changer provided with covers
A tool changer configured so that a turret is turned to index a desired tool to change the tool is provided with front and rear covers that cover front and rear surfaces, respectively, of the turret. A projection or a recess, which defines a passage for chips or a cutting fluid, is formed on or in an outer peripheral portion of the rear cover. Thus, the chips produced during machining and the cutting fluid used in the machining can be prevented from getting into the turret through a gap between the front and rear covers.
US09597754B2 Copper or copper alloy, bonding wire, method of producing the copper, method of producing the copper alloy, and method of producing the bonding wire
Copper or a copper alloy characterized in having an α-ray emission of 0.001 cph/cm2 or less. Since recent semiconductor devices are produced to have higher density and higher capacity, there is greater risk of soft errors caused by the influence of α rays emitted from materials positioned near semiconductor chips. In particular, there are strong demands for achieving higher purification of copper and copper alloys which are used near the semiconductor device, such as copper or copper alloy wiring lines, copper or copper alloy bonding wires, and soldering materials, and materials reduced in α-ray emission are also demanded. Thus, the present invention elucidates the phenomenon in which α rays are emitted from copper or copper alloys, and provides copper or copper alloy reduced in α-ray emission which is adaptable to the demanded material, and a bonding wire in which such copper or copper alloy is used as its raw material.
US09597737B2 Tool coupling arrangement for drills and reamers
A tool coupling arrangement for drills and reamers includes tool and shank portions with respective tool and shank axial stoppers. An at least partially cylindrical tool coupling end of the tool portion is located within a longitudinal through forward bore portion in the shank portion, and being coupled therein via an elongated coupling member located further inwards in the shank portion and comprising axially opposite member coupling and pulling ends. The forward bore portion has front and rear sub-portions and a bore recess which is located therebetween and extends radially outwardly. In a locked position, the tool axial stopper abuts the shank axial stopper. The tool coupling end abuts the front and rear sub-portions. And the member coupling end is wedged between the tool coupling end and the bore recess.
US09597734B2 Electrostatic chuck and showerhead with enhanced thermal properties and methods of making thereof
Embodiments of the present disclosure generally provide chamber components with enhanced thermal properties and methods of enhancing thermal properties of chamber components including bonding materials. One embodiment of the present disclosure provides a method for fabricating a composite structure. The method includes applying a bonding material to a first component, and converting the bonding material applied to the first component to an enhanced bonding layer by heating the bonding material to outgas volatile species from the bonding material. The outgassed volatile species accumulates to at least 0.05% in mass of the bonding material. The method further includes contacting a second component and the enhanced bonding layer to join the first and second components.
US09597733B2 Cutting insert, cutting tool, and method of producing machined product
A cutting insert may have an upper surface, lower surface, side surface, and a polygonal plate shaped to form a cutting edge at a ridgeline where the upper surface and the side surface intersect. The upper surface has a major part having a flat upper end surface, a first protrusion protruding from the major part toward a corner part of the upper surface, a second protrusion protruding from the first protrusion toward the corner part, and a pair of projections located between the second protrusion and the cutting edge. A height of an upper end of the first protrusion from the lower surface is lower than a height of the upper end surface of the major part and is higher than a height of the cutting edge. A height of an upper end of the second protrusion from the lower surface is equal to the height of the cutting edge.
US09597732B2 Flow restrictor assemblies including a monolithic flow restrictor and methods for manufacturing the same
Flow restrictor assemblies including a monolithic flow restrictor and methods for manufacturing the same are provided. The monolithic flow restrictor is configured for disposing in a fluid passage of a housing body. The monolithic flow restrictor comprises a first end and a second end, a first screen at the first end and a second screen at the second end, and a series of cross-sectional portions between the first screen and the second screen. Each cross-sectional portion has a plurality of slots formed in a radially outer surface thereof for connecting a series of restricting orifices formed in the monolithic flow restrictor for tortuously conducting a fluid through the series of cross-sectional portions.
US09597727B2 Water cooling apparatus for centrifugal casting equipment
A water cooling apparatus for cooling centrifugal casting equipment that includes an upper mold and a lower mold rotating together includes a rotating shaft in which a first cooling passage is formed and to which a nozzle is provided at an end portion of the rotating shaft, and a collecting portion which surrounds a side surface of the lower mold and is installed apart from the lower mold. The lower mold is connected to the rotating shaft and includes a chamber separated from a mold space formed between the upper and lower molds in order to store cooling water injected to the nozzle. The lower mold includes at least one second cooling passage extended from the chamber toward an outer circumference surface direction, and the collecting portion receives the cooling water discharged through the second cooling passage.
US09597726B2 Metal melt circulating drive device and main bath including the same
A melt circulating drive device mounted on a side wall of a main bath and driven to agitate nonferrous metal melt present in a melt storage room storing nonferrous metal melt of the main bath. The melt circulating drive device includes a melt drive tank, a melt drive unit, and a partition plate. The melt drive tank includes a hermetically-sealed drive chamber including an opening allowing the drive chamber to communicate with the melt storage room, and the melt drive tank stores melt, which flows from the opening, in the drive chamber. The melt drive unit includes a permanent magnet unit rotated about a first up and down axis while making magnetic lines of force up and down pass through the melt, and a drive unit for the permanent magnet unit that rotates the melt, about the first up and down axis by rotationally driving the permanent magnet unit.
US09597724B2 Wire twisting tools and methods
A wire twisting tool provides a rotatable jaw housing defining an interior cavity and a housing slot shaped for receiving one or more strands of wire. One or more jaw members are disposed in the interior cavity of the jaw housing. The jaw housing is generally rotatable relative at least one jaw member. At least one jaw member advances inwardly during jaw housing rotation and is operable to engage the wire. One or more jaw members can be rotated simultaneously with the jaw housing for twisting the wire. Methods of twisting wire using a wire twisting tool are also provided.
US09597716B2 Dry-type cleaning chassis, dry-type cleaning device, and dry-type cleaning system
A dry-type cleaning chassis for cleaning a cleaning target by colliding the cleaning media with the cleaning target, the cleaning media being blown by an air flow includes an internal space where the cleaning media are to fly; an opening part being in contact with the cleaning target so that the cleaning media collide with the cleaning target; an air inlet duct introducing external air into the internal space; a suction port generating a first air flow caused by a circulating air flow in the internal space by suctioning the introduced external air; an injection port generating at least a second air flow increasing a speed of the cleaning media flown by the circulating air flow; and a porous unit passing objects removed from the cleaning target to a suction port side.
US09597714B2 Routing of an unknown mail item
Apparatus, methods, media and code for routing a mail item part are provided. A receiver may receive an image of the mail item part. A processor may decompose a segment of the mail item part into a string vector; quantify a first closeness between the string vector and a first library vector that corresponds to a first mail item part destination; and quantify a second closeness between the string vector and a second library vector that corresponds to a second mail item part destination; and link to the image routing information to route the mail item part to that of the first and second mail item part destinations that corresponds to the greatest of the first and second closeness. A transmitter may transmit the image to that of the first and second mail item part destinations that corresponds to the greatest of the first and second closeness.
US09597713B2 Cotton feeding unit
A cotton feeding unit has a radial type aspirator; primary cotton filter that enables cotton suction; secondary cotton filter that captivates dust; linear motion chassis of primary and secondary filters that carries cyclones and allows linear motion; primary filter rotary valve that enables cotton to land on transfer conveyor; horizontal cotton transfer conveyor that transfers landed cotton; air box that screens the warehouse with flexible hose mobile crane and connects hose and suction nozzle with air box; cotton fine dust bag filter that captures particles; cotton suction venturi nozzle mobile collection arm that unlooses hardened cotton; secondary filter butterfly valve that discharges contaminated water containing dust from cyclone to filter cabin; secondary filter cake cabin that collects accumulated amount discharged from cyclone; secondary filter atmosphere exit bag filter dust collection cabin which collects particles held by cotton fine dust bag; tremie intake-storage filling rotary flap that enables delivery of cotton.
US09597703B2 Slit nozzle
A slit nozzle for dispensing liquid onto a surface of a wafer, comprises a nozzle body having a discharge opening whose length is from 10-100 mm and whose width is from 0.5-5 mm. The nozzle body has a dispensing chamber positioned upstream of the discharge opening and extending to the discharge opening, and a liquid distribution chamber positioned upstream of the dispensing chamber. The dispensing chamber and the liquid distribution chamber are in fluid communication with one another and are separated by a reduction section of the nozzle body whose cross-sectional area is at least 20% less than a cross-sectional area of each of the discharge opening and the liquid distribution chamber.
US09597700B2 Method and system for generating vapors of liquid solutions
A method and system for generating vapors of liquid solutions where a pneumatically modulated liquid delivery system maintains a defined flow rate for a liquid solution. The pneumatically modulated liquid delivery system includes a flow meter configured to measure a flow rate for the liquid solution flowing from a pressure vessel; a microcontroller configured to determine a pressure necessary to achieve the defined flow rate; and an electronic pressure control unit configured to adjust the pressure inside the pressure vessel. The system includes a nebulizer coupled to the pneumatically modulated liquid delivery system configured to receive the liquid solution from the pneumatically modulated liquid delivery system at the defined flow rate and configured to generate an aerosol of the liquid solution. A heat tube can vaporize the aerosol generated by the nebulizer.
US09597698B2 Multi-chamber container
Provided is a multi-chamber dispenser (1) of flowable substances, comprising: a rigid body (100) disposed around first (113) and second (123) storage chambers for storing respective first and second flowable substances, a first inlet fluidly connecting the first storage chamber (113) with a first outlet (141), a second inlet fluidly connecting the second storage chamber (123) with a second outlet (151), a first user-operable apparatus (140) at an exterior of the container and configured, on movement relative to the rigid body (100), to cause a volume of the first flowable substance to be dispensed from the first storage chamber (113) via the first inlet to the first outlet (141), and a second user-operable apparatus (150) at the exterior of the container and configured, on movement relative to the rigid body (100), to cause a volume of the second flowable substance to be dispensed from the second storage chamber (123) via the second inlet to the second outlet (151).
US09597697B2 Apparatus for the coating of a substrate
The invention relates to an apparatus for the coating of a substrate, in particular of a circuit board, with a material application device for applying a coating material and with a gas supplying device for the supply of a gaseous medium, the material application device having an inner tubular element, the gas supply device having an outer tubular element which is arranged coaxially to the inner tubular element and surrounds the latter, so as to form between the outer and the inner tubular element a gas supply duct which has an annular orifice at one end, the supply duct being configured so that the gaseous medium flows out, parallel to the coating material, through the annular orifice, in order, when it impinges on the substrate, to displace the applied coating material and thereby distribute it over the area. The apparatus is distinguished in that the material application device has a jet valve which, in a first operating mode, carries out a jetted supply of material into the inner tubular element.
US09597696B2 Screen insert for a powder chamber of a powder supplying device
The invention relates to a screen insert (70) for a powder container (24) of a powder supplying device, the screen insert (70) having a screen unit (71) for screening coating powder and an ultrasonic transducer (72) for generating ultrasonic vibrations. The screen unit (71) is connected to the ultrasonic transducer (72) in such a way that the ultrasonic vibrations generated by the ultrasonic transducer (72) can be transferred to the screen unit (71). To allow a particularly compact construction of the screen insert (70) to be achieved, according to the invention a screen carrier (73) which can be placed onto the powder container (24) is provided, for holding the ultrasonic transducer (72), with the screen unit (71) connected thereto, in such a way that the screen unit (71) is arranged below the screen carrier (73), so that the screen unit (71) is inside a powder chamber (22), formed by the powder container (24), when the screen carrier (73) has been placed onto the powder container (24).
US09597694B2 Pneumatic ported atomizing fluid delivery manifold
Systems, methods and apparatus are provided through which in some implementations a pneumatic ported atomizing fluid delivery manifold includes a fluid delivery housing, the fluid delivery housing having a frustum geometry, the fluid delivery housing has a first end and a second end, the first end has a first plane and the second end having a second plane, the fluid delivery housing has at least one chamber through which cleaning solution is operable to pass from the first end to the second end, and a free-floating pneumatic rotating exit tube positioned along a longitudinal center axis of the fluid delivery housing, the free-floating pneumatic rotating exit tube have only air passing through the free-floating pneumatic rotating exit tube.
US09597691B1 Producing particle dispersions
An improvement in an apparatus and a method produces a particle dispersion by processing a particle-carrying feedstock passed from a supply vessel through a bed of media contained within a containment wall having an inlet end and a longitudinally opposite terminal end. An auxiliary chamber surrounds the containment wall so that the feedstock is passed from the bed of media, through the containment wall and into the auxiliary chamber while the media is contained within the bed of media. An external pumping mechanism established a pressure differential that draws the feedstock into the containment wall and through the bed of media, then through the containment wall into the auxiliary chamber, and then out of the auxiliary chamber at a location juxtaposed with the containment wall between the inlet end and the terminal end, while maintaining a negative pressure within the supply vessel and within the auxiliary chamber during processing of the feedstock.
US09597690B2 Mineral material processing plant and a method for operating a processing plant
A mineral material processing plant includes a mineral material processing apparatus and a first conveyor which is arranged to feed the processing apparatus during operation of that processing apparatus. The first conveyor includes a first material transport part, a second material transport part and a pivot by which the second material transport part is fixed in relation to the first material transport part. The first conveyor is pivotable to an operation position in which the transported material is arranged to be fed via a discharge end of the second material transport part to the processing apparatus and to a service position which is in a first pivoting direction in relation to the operation position. In the service position, the projection of the discharge end of the second material transport part is arranged to leave free the lifting center of the processing apparatus when viewed from above. A method for operating a processing plant is also disclosed.
US09597688B2 Polymer substrate with fluorescent structure, method for the production thereof and the use thereof
The invention relates to polymer substrates which are provided with fluorescence features and in which photochemical fluorescence features, i.e. fluorescent structures, are produced by UV irradiation. Thus, fluorophores can be produced in polymer substrates with a low inherent fluorescence by means of suitable UV radiation, which fluorophores display a marked and detectable emission upon being excited with light of a suitable wavelength. If such an irradiation is implemented in a structured manner, emission patterns can be produced in this way in polymer substrates, which emission patterns can be applied for example as recovery grids in fluorescence microscopy. A further application field relates to product authentication which is made possible by the polymer substrates according to the invention provided with fluorescence features.
US09597684B2 Method for making hydrophobic barriers in paper
Provided is a method of patterning a substrate. The method includes depositing, in a first predetermined pattern, hydrophobic material on a first surface of a hydrophilic substrate. The method includes permeating the hydrophobic material through a thickness of the substrate without reflowing the deposited hydrophobic material. The method includes sufficiently solidifying the permeated hydrophobic material. The sufficiently solidified hydrophobic material forms a liquid-impervious barrier that separates the substrate into at least one discrete region.
US09597682B2 Devices and methods for capturing target molecules
Provided herein are devices and methods for the capture or isolation of a biomarker from a biological sample. In several embodiments, the device comprises a loading region, a filter material, and a receiving region. In particular, in several embodiments, biological fluid is passed from the loading region through the filter material and into the receiving region, thereby resulting in capture or isolation of a biomarker.
US09597681B2 Sensor element, method for manufacturing sensor element, and sensor cartridge
A sensor element comprising a tape-shaped mount film; and a plurality of film-shaped sensors bonded on one surface of the mount film, wherein the front and rear film-shaped sensors are spaced at a predetermined distance in a lengthwise direction of the mount film, and a crosswise length of each film-shaped sensor is shorter by a predetermined quantity than a crosswise length of the mount film.
US09597679B2 Integrated acid regeneration of ion exchange resins for industrial applications
Methods and systems for an integrated acid regeneration of ion exchange resins are disclosed for use in cleaning applications. Acid resins designed for use in a variety of cleaning application using a treated, softened, acidic water source are disclosed. Various methods of using the softened acidic water generated by acid regenerate-able ion exchange resins within a cleaning application, e.g. ware wash machine, are disclosed to beneficially reduce spotting, filming and scale buildup on treated surfaces, reduce and/or eliminate the need for polymers, threshold reagents and/or rinse aids, and using protons generated in the acidic water effluent for triggering events useful in various cleaning applications.
US09597676B2 Stable catalysts for electroless metallization
Aqueous catalysts of nanoparticles of precious metals and stabilizers of flavonoid derivatives are used to electrolessly plate metal on non-conductive substrates. Such substrates include printed circuit boards.
US09597665B2 Catalyst system for exhaust gas purification and method for exhaust gas purification
In an exhaust gas purification catalyst system for use in an automobile including an exhaust gas purification catalyst product disposed in both a front section and a rear section, the exhaust gas purification catalyst product of the front section has a layered catalyst including a lower layer which contains aluminum borate.
US09597663B2 Exhaust cleaning catalyst
An exhaust cleaning catalyst, with which precious metal sintering is inhibited and which has greater exhaust cleaning abilities, has a substrate and a catalyst coating layer provided on the substrate. The catalyst coating layer has a precious metal that serves as an oxidation and/or reduction catalyst. The precious metal has Rh-containing metal particles in which rhodium (Rh) coexists with a base metal selected among platinum group elements excluding rhodium. The Rh-containing metal particles have an average rhodium content of 0.1% to 5% by mole with the total amount of the base metal and rhodium being 100% by mole.
US09597659B2 Heterogeneous catalyst of the zinc aluminate spinel type surstoichiometric in zinc and use thereof in a process for preparation of alcohol esters from triglycerides and alcohols
A catalyst with a mixed zinc and aluminum oxide base having a spinel structure surstoichiometric in zinc, in which part of the Zn atoms are in the octahedral position, a process for preparation of the same and use of the same in a process for preparation of a compound of linear monocarboxylic acid alcohol esters with 6-26 carbon atoms from a vegetable or animal oil, neutral or acid, virgin or recycled, with monoalcohols of 1-18 carbon atoms allowing an ester that can be used as a motor fuel or a heating fuel and a pure glycerine to be obtained directly in one or more steps.
US09597655B2 Boron selectivated molecular sieves and their use in sorptive separations
A composition is described comprising a molecular sieve having pores defined by channels formed by one or more 8-membered rings of tetrahedrally coordinated atoms, such as a DDR-type molecular sieve, and an amorphous deposit of a boron compound on the molecular sieve.
US09597649B2 Fluid bed granulation process and apparatus
Fluid bed granulation process of an appropriate substance, comprising the cooling in a second fluid bed of the granules obtained. The same flow of fluidification air is used to form and support both fluid beds.
US09597648B2 Non-spherical droplet
Non-spherical liquid droplets comprising a liquid, an internal solid material defining the shape of the droplet, a benefit agent, and methods of making non-spherical liquid droplets.
US09597647B2 Mixer with indirect steam heating and/or water heating or cooling
The present invention relates to a mixer with a drum that comprises a mantle, a bottom and a top and which rotates around an axis of rotation.
US09597639B2 Hollow fiber membrane module, filtration apparatus using the same, and method for manufacturing the filtration apparatus
Disclosed are a hollow fiber membrane module, a filtration apparatus based on the same, and a method for manufacturing the filtration apparatus. The hollow fiber membrane module includes two headers respectively provided with a permeate collecting unit therein, wherein each of the headers has grooves on its two sides, the grooves being extended in a length direction of the hollow fiber membrane. Since one slide rod can simultaneously be inserted into grooves of two adjacent hollow fiber membrane modules, the hollow fiber membrane modules can mutually serve as guides for insertion/ejection thereof. Also, since the grooves formed on the header can serve as insertion holes into which a clamp is inserted, the clamp can be used for coupling between the hollow fiber membrane module and another element and reinforcement of the coupling.
US09597635B2 Zeolite promoted silver based catalyst for NOx storage
An aftertreatment system utilizes chemical reactions to treat an exhaust gas flow. A device for use within an aftertreatment system includes a silver-based NOx storage catalyst and a zeolite. The silver-based NOx storage catalyst and the zeolite store NOx through a low temperature startup period of operation. In one embodiment, the zeolite includes a barium Y zeolite.
US09597629B2 Method and device for separating off carbon dioxide from a gas mixture
A method for separating off carbon dioxide from a gas mixture, in particular from breathing air, with a life-sustaining device, wherein in a first method step the gas mixture is fed to an adsorption and/or absorption unit under at least one first pressure, and in a second method step a gas mixture is conveyed out of the adsorption and/or absorption unit under at least one second pressure that is higher than the first pressure.
US09597627B2 Regenerative air purification system and method
The invention provides a system for regenerative air purification and a method thereof. The system includes a set of gas sensors, a processor, an adsorption gas filters with TiO2 (or TiO2 mixed activated carbon material) coated on the outer surface, a set of auto valves, a set of UV lamps, and a heater near the adsorption filter. The processor is configured to receive input data from the gas sensors and to control the system. During an air cleaning phase, the air is ventilated through the adsorption filter and VOCs are trapped therein. During a regenerative phase, the UV lamps and heater are turned on and the adsorption filter media will be cleaned up via the combined approaches including the heating of the heater, photo-catalytic oxidation and a reversed air flow.
US09597625B1 Method of manufactring an antibacterial filter comprising copper-based compound particles
Provided is a method of manufacturing an antibacterial filter including copper-based compound particles. The method comprises the steps of preparing a porous medium containing minute pores allowing a fluid to pass therethrough and coating copper sulfide particles on inner surfaces of the minute pores of the porous medium. The sulfur compound particles have a chemical structure of CuxSy (wherein x/y=0.8 to 1.5).
US09597622B2 System and methods for removing entrained liquids
The present techniques are directed to a method for removing entrained liquid hydrocarbons in a countercurrent contact separator to produce a lean hydrocarbons gas. The method includes introducing a gas stream into an inlet of the countercurrent contact separator and flowing the gas stream through a bulk separator to capture a portion of the entrained liquid hydrocarbons. The method includes flowing the gas stream through a plurality of cyclone bundles, where the plurality of cyclone bundles are located in risers to capture a remaining fraction of the entrained liquid hydrocarbons. The method includes flowing the captured entrained liquids downward into a drain line countercurrent to the gas stream. The method includes removing the captured entrained liquids through a bottom outlet of the countercurrent contact separator. The method includes removing the lean hydrocarbons gas through a top outlet of the countercurrent contact separator.
US09597619B2 Debris filter sensor
In one embodiment, a piezoelectric device is positioned adjacent to a debris fence. A resonant frequency detection circuit connects with the piezoelectric device. The resonant frequency of the piezoelectric device is responsive to debris adjacent to the debris fence.
US09597618B2 Systems and methods for extracting sand from raw slurry material
A processing system for processing raw slurry material has a barrel member, at least one transport member, and at least one separator member. The barrel member defines a processing chamber and at least one intermediate opening. The processing chamber defines a pre-processing portion and a separator portion. The at least one transport member is arranged within the pre-processing portion of the processing chamber. The at least one separator member is arranged within the separator portion of the processing chamber and configured to define at least one separator gap. As the barrel member rotates about a longitudinal axis thereof, the at least one transport member transports at least a portion of the raw slurry material through the pre-processing portion of the processing chamber, and the at least one separator member transports at least a portion of the raw slurry material through the separator portion of the processing chamber.
US09597615B2 Flow development chamber and separator
A fluid handling and separation system has an inlet conduit for receiving a helical fluid flow, a housing connected to the inlet conduit, a collection conduit disposed within the housing in axially alignment with the inlet conduit, and a diversion conduit in fluid communication with the interior of the housing. The housing encloses the collection conduit to form an annular space between the interior surface of the housing and an exterior surface of the collection conduit. Upon receiving a helical flow via the inlet conduit, a radially outward portion of the helical flow is separated from a radially inner portion of the helical flow. The radially outward portion of the helical flow is diverted through the diversion conduit while the radially inward portion of the helical flow is received by the collection conduit. Such a system allows for separating the helical fluid flow by density of materials or fluids within the helical fluid flow.
US09597612B2 Analysis device including solid-phase extraction material filling and discharging mechanisms
Provided is an analyzer performing solid-phase extraction of a measurement component (i.e., component to be measured) in a sample solution while decreasing an amount of waste generated and reducing a running cost. The analyzer includes: a solid-phase extraction container having a body part to receive a sample solution containing a measurement component of analytical target and a discharge passage to discharge the sample solution. Herein, the discharge passage is to be filled with a solid-phase extraction material for subjecting the measurement component to solid-phase extraction. The analyzer further includes a supplying mechanism for a solid-phase extraction material; a filter supplying mechanism; a determining mechanism for filling position; a discharging mechanism for discharging the filter and the solid-phase extraction material after the solid-phase extraction of the measurement component; and a container cleaning mechanism for cleaning the solid-phase extraction container from which the solid-phase extraction material is removed.
US09597609B2 Multi-stage crystallisation process and apparatus to purify a compound
A process to purify a compound comprising a suspension crystallization step and additionally comprises a layer crystallization step and a storage step of an intermediate product obtained from the layer crystallization step before to its further purification in the suspension crystallization step.
US09597608B2 Cryopump system
A cryopump system includes: a plurality of cryopumps connected to a common roughing pump in a rough line and provided with a plurality of rough valves in the rough line, respectively; and a controller configured to control each of the rough valves for regenerating a corresponding one of the plurality of cryopumps. A delay time is set between closing of an open one of the plurality of rough valves and opening of a closed one of the plurality of rough valves. The controller applies the delay time uniformly upon closing of each of the rough valves.
US09597607B2 Modular electronic building systems with magnetic interconnections and methods of using the same
Electrical connectors, electrical modules, and systems are provided. In one aspect, an electrical connector includes a housing defining a side surface, an electrical conductor supported by the housing and including an engagement portion proximate the side surface of the housing. The engagement portion is adapted to engage another electrical conductor of another electrical connector. The connector also includes a magnet supported by the housing proximate the side surface of the housing, a projection extending from the side surface of the housing, and a receptacle defined in the side surface of the housing. In other aspects, an electrical module includes at least one of these electrical connectors. In further aspects, a system includes a plurality of these modules and the modules are selectively couplable together.
US09597602B2 Information processing system, information processing device, storage medium storing information processing program, information processing method, and storage device
An example of information processing system includes a storage device; and an information processing device for performing near field communication with the storage device. The storage device has an external appearance representing, three-dimensionally or two-dimensionally, an object that appears in a virtual space generated by execution of a predetermined application program by the information processing device. The storage device stores object information on the object. The information processing device writes, to the storage device, character image information specifying an image of a character created based on an instruction of a user. The information processing device executes a predetermined process using at least one of the object information and the character image information read from the storage device.
US09597601B2 Method for displaying chat window applied to network game
Players input their messages in their video game apparatuses and the messages are once collected at a server apparatus, thereafter they are distributed to all video game apparatuses from the game server apparatus. In a display screen of each video game apparatus, a chat window is displayed in order to display messages exchanged between the players on a game screen including a field and characters of the game. The chat window is sequentially enlarged up to a preset maximum number of lines when a new message is received from the game server apparatus. The chat window is sequentially reduced to the preset minimum number of lines when a predetermined time passes without any reception of new message or when the player performs a specific operation.
US09597600B2 Systems and methods for generating video hints for segments within an interactive video gaming environment
Systems and methods for generating hints for a player with an interactive video gaming environment are provided. A plurality of videos from users is received at a remote server. Each of the plurality of videos includes a hint that corresponds to a different one of a plurality of segments within the interactive video gaming environment. An action relating to game play in the interactive video gaming environment is received at the remote server from player equipment. A determination is made as to whether the action is associated with one of the plurality of segments. In response to determining the action is associated with one of the plurality of segments, one of the plurality of videos that includes the hint that corresponds to the one of the plurality of segments associated with the action is selected. The selected one of the plurality of videos is transmitted to the player equipment.
US09597599B2 Companion gaming experience supporting near-real-time gameplay data
A companion gaming experience is associated with a particular game title, but a user interface for the companion gaming experience is generated by a separate program from the associated game title and is presented on a device separate from the device on which the game user interface itself is presented. When an associated game of the video game title is not running, the companion gaming experience presents guide information and/or statistics data for the game title. However, when an associated game of the game title is running, the companion gaming experience presents gameplay data for the game in near-real-time.
US09597589B2 Input device
An input device (1) for data processing apparatus (12) comprises a dish (2) having a convex lower surface (3) which rests on a base (10) and can tilt in a plurality of directions with respect to the base, and a concave upper surface (5) in which is positioned a movable member such as a ball (6) which can move with respect to the concave upper surface. A user is supported on the movable member, in a standing, sitting or kneeling position. The dish is provided with a motion detector module (8) which detects movement of the dish in response to forces applied to the dish as a result of actions performed by the user, and which produces signals in response to such movement. An interface (9) serves to output the signals to the data processing apparatus.
US09597576B2 Method and device for improving putting
Implementations of the present invention provide systems and methods for providing a golfer putting information. Preferred embodiments may provide a golfer with optimal ball trajectory, including the initial path the ball should be stuck on, point to which the ball should be struck and optimal force with which the ball should be struck. In preferred embodiments a golfer utilizes a mobile putting device, which may be placed anywhere on or around a putting surface, where a putting surface may be any suitable environment for striking a golf ball with a putter. Preferred embodiments of the putting device are structured to allow alignment with the cup and/or stationary object, indicate where the ball should be placed, indicate the optimal line on which the ball should be struck and the computed force with which the ball should be struck. Some embodiments are structured to provide a golfer with feedback on the distance a practice swing would move the ball if struck, or after an actual putt, how hard the ball was hit with respect to the calculated target.
US09597575B2 Storage at indoor golf driving range
Systems and methods are disclosed for providing storage at indoor golf driving ranges. In various embodiments, the disclosed systems and methods permit golfers to store their baggage in close proximity to the golfers while the golfers practice their swing.
US09597571B2 Unbalanced weighted apparatus with a heavy end and a light end
A weighted apparatus, such as a bat, bar, stick, racket, or club, includes added weight in one end of the apparatus to create an obviously heavy end, and thereby an unbalanced apparatus. The unbalanced apparatus gives the user the ability to create a heavy load to build strength by holding the light end of the device and a light load to build speed, endurance, and flexibility by holding the heavy end of the device. When swung holding the heavy end, such an unbalanced apparatus is uniquely effective for various sports practice regimens, certain game play, general exercise, physical rehabilitation, etc., to improve the user's strength and overall conditioning levels, to build hand speed and to promote a proper swing.
US09597569B2 Street hockey puck
An improved hockey puck for use on unsmooth surfaces such as streets and parking lots consisting of two generally equal sized disks. Sandwiched between the two disks is an energy absorbing member or members. Springs or foam washers can serve as these members. The two disks are loosely connected together so that only one will receive the direct impact from striking a imperfection in the street or other playing surface. The energy absorbing members dampen the forces transferred between the two puck disks. This results in a puck which can travel across rough surfaces with a greatly reduced likelihood of tumbling or bouncing. The improvement of the hockey puck specifically consists of the addition of a fortifying member positioned within either or both disks of the improved hockey puck.
US09597568B2 Target for a thrown object with rapid deploy features
A target device for registering a hit by a thrown object such as a flying disc is provided and includes a pylon assembly, an interceptor, and a receipt component. The pylon assembly, the interceptor, and the receipt component are operatively associated with one another such that a movement of the pylon assembly from its operating disposition to its stowage disposition operates to move the interceptor and the receipt component axially closer to the base axial end of the pylon assembly and, when the pylon assembly is in its stowage disposition, the interceptor has been moved from its intercepting position into its non-intercepting position, and the receipt component has been moved from its flared position into its pack position, the interceptor and the receipt component at least partially axially overlap one another.
US09597567B1 Smart sport device
An Internet of Thing (IoT) sport device includes a light source; sensors including a camera and a microphone array; a processor coupled to the light source and the sensor; and a wireless transceiver coupled to the processor.
US09597562B2 Iron type golf club head
Iron-type golf club heads are disclosed having a heel portion, a sole portion, a toe portion, a top-line portion, a front portion, a rear portion, and a striking face. The iron-type golf club heads include a localized stiffened region that is located on the striking face of the club head such that the localized stiffened region alters the launch conditions of golf balls struck by the club head in a way that wholly or partially compensates for, overcomes, or prevents the occurrence of a rightward deviation. In particular, the localized stiffened region is located on the striking face such that a golf ball struck under typical conditions will not impart a right-tending sidespin to the golf ball.
US09597560B2 Golf club head
A golf club head of the present invention includes a hosel portion in which a shaft is inserted, the hosel portion being provided on a heel side of the golf club head, and an extended portion that extends from the hosel portion to a back side of the golf club head. The extended portion includes a distal end portion on a face portion side and a rear end portion on the back side. Out of a heel-side portion and a toe-side portion of the hosel portion, the distal end portion is connected to the heel-side portion. The rear end portion is located on the toe side with respect to the distal end portion.
US09597559B2 Golf club head with variable thickness face to body transition
A golf club having variable face to body transition is disclosed herein. More specifically, the present invention relates to a golf club head having an indented transition region that helps facilitate the transition of thickness variation from the striking face to a rear aft body. The indented transition region may be located on the crown, the skirt, or the sole, and achieves improved performance by achieving an increased thickness reduction slope.
US09597549B2 Multi-layer core golf ball
Golf balls comprising a multi-layer core and a cover are disclosed. The multi-layer core comprises a center and an outer core layer that are both soft relative to a hard intermediate core layer. The Shore C hardness of the outer surface of the center is preferably greater than the Shore C hardness of the geometric center of the center.
US09597548B2 Golf ball including a blend of highly neutralized acid polymers and method of manufacture
A golf ball having an inner core layer, an outer core layer enclosing the inner core layer, and a cover layer enclosing the outer core layer. The inner core layer includes a blend of a first highly neutralized acid polymer having a first Vicat softening temperature and a first specific gravity, a second highly neutralized acid polymer having a second Vicat softening temperature and a second specific gravity, and an ionomer-based masterbatch comprising an additive and an ionomer resin having a third Vicat softening temperature and a third specific gravity. The absolute values of the differences among the Vicat softening temperatures is no more than about 15° C. and the absolute value of the difference between the specific gravities is no more than about 0.015. The cover layer may include an inner cover layer enclosing the outer core layer and an outer layer enclosing the inner cover layer.
US09597538B2 Flame retardant and fire extinguishing product for fires in liquids
A novel flame retardant and fire extinguishing product for preventing and fighting fires in liquids is disclosed herein. The product comprises water, one or more flame retardants, one or more polymers, one or more surfactants, one or more emulsifiers, one or more preservatives, and one or more firming agents. In some embodiments, the product may further comprise one or more stabilizers, one or more binders, and/or one or more fining agents. The product may be used as a fire extinguishing agent in active firefighting and as a flame retardant to prevent fires. The product may be biodegradable in a natural environment, may be readily cleaned off equipment and materials to which it has been applied using water, and may also provide other features which render it safe for the environment as compared to other commonly used products in fire prevention and firefighting.
US09597537B2 Injection head having silencing function for gas type fire extinguisher
To present an injection head having silencing function for gas type fire extinguisher capable of reducing the noise generated upon release of fire extinguishing gas.In a gas type fire extinguisher using a fire extinguishing gas, a silencer 3A is disposed in an injection head 1A installed for releasing a fire extinguishing gas into a fire extinguishing area.
US09597536B1 Quint configuration fire apparatus
A quint configuration fire apparatus includes a ladder assembly and a single rear axle coupled to a chassis. The single rear axle includes either a single solid axle configuration extending laterally across the chassis or a first axle having a first constant velocity joint and a second axle having a second constant velocity joint. The ladder assembly is extensible to provide a horizontal reach of at least 90 feet and a vertical height of at least 95 feet and configured to support a tip load of at least 750 pounds. A water tank is configured to contain at least 500 gallons of water. The center of gravity of at least one of the chassis, a body assembly, a pump, and the water tank are positioned to counterbalance a moment generated by the tip load with the ladder assembly extended to the horizontal reach of at least 90 feet.
US09597535B2 Fire protection trolley and fire protection device comprising a fire protection trolley of this type
A fire protection trolley for securing a burning or flammable article, in particular for the interior of an aircraft or spacecraft, includes a sealable, fire-resistant safety container, and an interface connected to the safety container and formed for connection to a counterpart interface of a smoke gas exhaust line for removing a medium located in the safety container. A fire protection device has a fire protection trolley of this type which may be included in an aircraft or spacecraft.
US09597533B2 Fire suppression system
A fire suppression system according to an exemplary aspect of the present disclosure includes, among other things, a high pressure inert gas source configured to provide a first inert gas output and a low pressure inert gas source configured to provide a second inert gas output. A distribution network is connected with the high pressure inert gas source and the low pressure inert gas source to distribute the first inert gas output and the second inert gas output throughout a confined space. A volume reduction system is positioned within the confined space and includes a seal member. The seal member is selectively deployable between a first position and a second position to isolate a first volume of the confined space from a second volume of the confined space and reduce an amount of the first inert gas output and the second inert gas output required to respond to a fire threat within the confined space.
US09597532B2 Breathing apparatus, and method for controlling temperature fluctuations
A wearable breathing apparatus includes a thermal capacitor that a user inhales and exhales through. Inhaled air is cooled as it passes through the thermal capacitor, and exhaled air cools the material of the thermal capacitor for the next breathing cycle. The breathing apparatus may be used by a firefighter, for example, as a lightweight apparatus to enable the firefighter to safely breathe dangerously heated air, for example while in a fire shelter, that may otherwise cause injury to the user. The breathing apparatus advantageously does not require external power for cooling. The thermal capacitor may also be used as a part of a rebreather that uses a scrubber that removes carbon dioxide from exhaled air, for rebreathing. Further, the thermal capacitor may be used for other purposes, such as in recirculation of building air.
US09597527B2 Enhancement of penetration and action
Described is a dermal system which contains at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal system can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient. The at least one light source is a thin light source comprising at least one inorganic light emitting diode (LEDs) and/or at least one organic light emitting device.
US09597525B2 T-wave oversensing rejection
A medical device coupled to extracardiac electrodes is configured to analyze a cardiac electrical signal over a signal analysis segment to determine if shockable rhythm classification criteria are met, determine that TWOS detection criteria are met for the signal analysis segment when a predetermined number of TWOS analysis windows are classified as TWOS, and classify the signal analysis segment as non-shockable in response to determining that the TWOS detection criteria are met.
US09597524B2 Defibrillator with dynamic ongoing CPR protocol
An automated external defibrillator (AED) (10) having a treatment decision processor (28) is described which follows a “shock first” or a “CPR first” rescue protocol after identification of a treatable arrhythmia, depending upon an estimate of the probability of successful resuscitation made from an analysis of a patient parameter measured at the beginning of the rescue. The invention may also follow different CPR protocols depending on the estimate. The invention also may use the trend of the measured patient parameter to adjust the CPR protocol either during a CPR pause or after the initial CPR pause. The AED (10) thus enables an improved rescue protocol.
US09597519B2 Implantable medical device for providing stimulation therapy
An electrical stimulation system provides stimulation therapy to a patient. The system includes a neurostimulation lead that contacts patient tissue and couples with an implantable stimulation device, such as an implantable pulse generator, that receives stimulation parameters for providing stimulation therapy to a patient. The implantable stimulation device includes a header with a plurality of connector assemblies that receive an end of the neurostimulation lead, and a case containing a charging coil and a telemetry coil coupled to programming circuitry on a printed circuit board, which is in turn coupled to the connector assemblies via a feedthrough assembly. The telemetry coil receives data from an external programmer and transmits the data to the programming circuitry, which in turn uses the data to communicate to the connector assemblies and the neurostimulation lead to provide stimulation therapy to a patient.
US09597517B2 Neurostimulation system with flexible patterning and waveforms
A neurostimulation system configured for providing neurostimulation therapy to a patient. A user customizes a pulse pattern on a pulse-by-pulse basis. Electrical stimulation energy is delivered to at least one electrode in accordance with the customized pulse pattern.
US09597516B2 Wireless communication device for medical telemetry
A device includes an antenna, a parasitic element, and a telemetry control module. The parasitic element modifies a radiation pattern of the antenna. The parasitic element has an impedance value that is adjustable, and the radiation pattern of the antenna depends on the impedance value of the parasitic element. The telemetry control module is configured to transmit data to a medical device using the antenna, receive data from the medical device using the antenna, and detect communication errors using data that is received from the medical device. Additionally, the telemetry control module is configured to adjust the impedance value of the parasitic element in response to detection of communication errors.
US09597510B2 Method and apparatus for determining left ventricular lusitropy
A chronically implanted medical device, connected to a medical electrical lead that includes a sensor, is used to detect diastolic dysfunction. A LV accelerometer signal is sensed through the sensor. Based on the LV accelerometer signal, a determination is made as to whether diastolic dysfunction data exists.
US09597506B2 System for neurostimulation and/or neurorecording
The disclosure describes devices, systems, and techniques for checking synchronization between two or more modules of a system. In one example, a first module is configured to output a therapy, and a second module distinct from the first module is configured to receive an alternating current (AC) power signal from an AC power source, monitor a characteristic of the AC power signal, determine, based on the characteristic of the AC power signal, a period of time during which the first module is expected to one of output the therapy or refrain from outputting the therapy, and check, during the period of time, a synchronicity between the first module and the second module.
US09597494B2 Systems, methods and devices for a skull/brain interface
Systems, methods and devices are disclosed for directing and focusing signals to the brain for neuromodulation and for directing and focusing signals or other energy from the brain for measurement, heat transfer and imaging. An aperture in the skull and/or a channel device implantable in the skull can be used to facilitate direction and focusing. Treatment and diagnosis of multiple neurological conditions may be facilitated with the disclosed systems, methods and devices.
US09597492B2 Lead with braided reinforcement
A therapy delivery element configured for at least partial insertion in a living body. A braided structure surrounds the conductor assembly. A distal end of the braided structure is attached to an electrode assembly and a free floating proximal end is located near a connector assembly. An outer tubing surrounds the braided structure. The outer tubing includes a proximal end attached to the connector assembly and a distal end attached to the braided structure near the electrode assembly. A proximal tension force applied to the connector assembly acts substantially on the outer tubing and the conductor assembly and a proximal tension force applied to the free floating proximal end acts substantially on the braided structure.
US09597491B2 Device for the sealing connection of a pressure hose with a grip element or with a connector of a surgical instrument
A device for the sealing connection of a pressure hose with a grip element of a surgical instrument. The device comprising at least one sealing element that, in an assembled state, is interposed between the grip element and the pressure hose in a connecting region to create a seal. A support element is provided and arranged in the connecting region in the interior of the pressure hose such that the sealing element is clamped, or can be clamped, between the support element and the pressure hose on one side and the grip element on the other side. In addition, a handle for a surgical device, in particular a cryogenic surgical instrument, comprising a grip element for holding the surgical instrument and comprising at least one pressure hose that is connected, or can be connected, with the grip element via the device for the sealing connection.
US09597490B2 Microneedle, microneedle array and production method therefor
The present invention provides a microneedle, comprising a shaft of a monocrystalline material having at least three walls which are formed by a crystal plane of the monocrystalline material; and a tip connected to an end of the shaft comprising at least three walls which are formed by a crystal plane of the material. The material is preferably silicon. Two of the walls of the tip are formed by the same crystal planes as two walls of the shaft. These two walls are formed by a <111> crystal plane. Preferably, three walls of the tip are formed by a <111> crystal plane.
US09597488B1 Apparatus for applying roll-on/rub-on medications
Apparatus for applying rub-on and roll-on topical products such as medications, pain relievers, deodorants, cosmetics, and any other product having a built in applicator to the user's skin surface in hard-to-reach locations without undo strain or injury. The apparatus comprises a chamber assembly and an elongated handle. The chamber assembly comprises a rounded hollow T-shaped body having a protrusion on one side with a threaded inner surface to receive the elongated handle. The elongated handle has a threaded end that is deeper than the protrusion of the chamber assembly. When a container is placed into the chamber assembly from the top section and the elongated handle is hand-tightened, the threaded end comes in contact with the container and holds it securely in place, allowing the user to apply rub-on and roll-on medications and other products to hard-to-reach places of the body without undo strain or injury.
US09597486B2 Methods for ameliorating pain and devices for delivering a medicament
A method for delivering medicament such as for ameliorating pain in a patient includes introducing an injector through a nasal passage of the patient into a region substantially medial and/or posterior and/or inferior to a sphenopalatine ganglion (SPG) of the patient; and delivering a medicament from the injector superiorly and/or laterally and/or anteriorly towards the SPG. A device for delivering a medicament to a patient in need thereof includes (a) an injector containing a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient; and (b) an introducer configured for engagement with a nostril of the patient and containing a passageway configured for slidably receiving the injector. The injector is moveable between a storage position preceding the engagement and an engaging position pursuant to the engagement.
US09597484B2 Surgical cavity drainage and closure system
A surgical drain device includes an adhesion matrix of biodegradable polymer material and a plurality of drain tubes attached to the matrix. The device is implanted within a surgical wound to treat the presence of seromas, for example, and is used to promote drainage, tissue adhesion, and wound closure. The drain tubes converge into a common collection tube that leads wound fluid outside the body under gravity feed or negative pressure applied to the collection tube. The matrix contains an array of apertures that allow tissue contact across the device. The device also can include a coating of surgical adhesive and a tissue anchoring system of hooks or barbs. The device and systems containing the device are particularly useful to promote the healing of surgical wounds from abdominal surgery.
US09597480B2 Intraluminal devices and systems
Medical devices, perfusion systems, and methods for detecting a pressure within a space in a subject and for perfusion of fluid into a space in a subject. The space may be a fluid-filled space, or a space that is depleted of fluid due to an obstruction to fluid flow into the space. Methods for forming the medical devices.
US09597468B2 Methods and apparatus for providing ventilation to a patient
The present technology relates to methods and apparatus to provide ventilation to patients. In particular, the present technology relates to changing ventilator parameters to match changing patient metabolic demand.
US09597464B2 Autoinjector with means for preventing reuse and disconnection of said first and second body portions after operation
An autoinjector has a body portion (10, 12) containing a syringe (13) or cartridge with a needle at its forward end, the autoinjector having a drive arrangement (60 . . . ) for effecting operation of the autoinjector and including a drive element that moves from a first position to a second position during the operation, the body including a first (10) and a second body portion (12) connected together by a snap fit arrangement including a resiliently moveable latch finger (138) on one of the body portions that cooperates with a latch surface (142) on the other thereof to hold the two portions connected, wherein the drive element in the second position (60) limits or prevents resilient movement of the moveable latch finger (142), thereby preventing disconnection of the first and second body portions after operation.
US09597457B2 Piston rod for a drug delivery device and drug delivery device comprising a piston rod
A piston rod for a drug delivery device comprises a main body and an engagement means for engaging the piston rod with a part of the drug delivery device. The engagement means are retractable relatively the main body for enabling a disengagement of the engagement means from the part of the drug delivery device.
US09597456B2 Injection device preventing the return of the piston when the safety system is deployed
An injection device includes: a body for receiving a product, a needle and a piston attached to a piston rod movable between a storage position and an end-of-injection position. The device further includes a sleeve for protecting the needle which is movable between an initial position where the needle is uncovered and a final position where the needle is covered, as well as biasing means for moving the sleeve from its initial position to its final position and immobilization means for keeping the sleeve in its initial position. The piston rod includes a first portion and a second portion, the second portion being able to switch between a locked position in which the second portion is fixed to the first portion and an unlocked position in which the second portion is movable with respect to the first portion on a predetermined distance along the longitudinal axis of the piston rod.
US09597454B2 Syringes for prefilled and fill-at-use mixing and drug delivery
Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject.
US09597453B2 Integrated insulin delivery system with continuous glucose sensor
Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
US09597438B2 Medical appliance
A medical appliance, in particular an apparatus for extracorporeal blood treatment, has a housing including a door and with a handle mechanism arranged at the door, via which the door can be locked with the housing via a locking mechanism. A part of the locking mechanism is formed at the handle mechanism in a part thereof that protrudes into the housing. A form-fit unit includes at least one form-fit element and at least one form-fit element counterpart, such that on locking and/or closing the door, the at least one form-fit element at least partly engages in the at least one form-fit element counterpart.
US09597437B2 Guidable intravascular blood pump and related methods
An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
US09597433B2 Non-pathogenic biofilms and uses thereof
In an embodiment, the present disclosure pertains to a method and compositions for modification of medical devices, such as indwelling medical devices, implantable catheters, in particular, urinary catheters, to enhance formation of a high density and stable biofilm comprising non-pathogenic organisms for the treatment and prevention of colonization of pathogens leading to device-associated infections, such as urinary tract infections. In some embodiments the present disclosure also relates to a method and compositions for storage and use of the catheters coated with a non-pathogenic biofilm. In some embodiments the present disclosure also pertains to a method and compositions for modification of implantable medical devices with bacterial resistant polymers, and/or antimicrobial agents.
US09597430B2 Synthetic structure for soft tissue repair
Synthetic structures for soft tissue repair include a multi-layer planar fibrillar structure having layers which are intermittently secured to each other and which approximates mechanical properties comparable to those of soft tissue. In embodiments, the fibrillar structure possesses an intermittently secured edge portion secured by intermittent welds. In embodiments, the multi layer planar fibrillar structure includes a bioactive agent.
US09597428B2 Collecting device for body fluids
A body waste collecting device includes a collecting pouch and an adhesive wafer for attachment to the body. The adhesive wafer includes a backing layer, a first adhesive and a second adhesive. The second adhesive includes a polar plasticizing oil or a combination of polar plasticizing oils in the content of above 10% (w/w) of the second adhesive, and at least one polar polyethylene copolymer, where the content of the polyethylene copolymer is 10-50% (w/w) of the second adhesive, and the polyethylene copolymer has a melt flow index below 2 g/10 min (190° C./21.1N).
US09597422B2 Disinfection of packaged articles
An apparatus for generating ozone inside packaged articles comprises an electrode assembly in which coplanar electrodes are supported along a contact surface. The electrodes are solid state conductive electrodes. These electrodes may be interdigitated and/or arranged with uniform spacing therebetween along a portion of their length. Where the electrodes are straight they may be parallel, but other shapes can also be evenly spaced. In some examples the electrodes are partially insulated and partially exposed. In some examples the electrodes are embedded/potted in an insulator to exclude air spaces from around the electrodes.
US09597421B2 Surface modified devices and sterile packaging therefor
A method for sterile packaging of a surface modified implantable device includes irradiating a surface of the device such that the hydrophobicity of the surface is decreased and, optionally, the device is simultaneously sterilized. The surface of the sterile, surface-modified implantable device is then covered in a polar solution to prevent hydrophobic recovery of the surface.
US09597415B2 Methods for expressing a polynucleotide of interest in the retina of a subject
Provided herein are methods for expressing a polynucleotide of interest in the retina of a subject. In particular, a method for expressing a polynucleotide of interest in the retina of a subject comprising the step consisting of injecting into the vitreous an amount of a vector containing the polynucleotide of interest in combination with an amount of an inhibitor of Dp71 expression is provided.
US09597412B2 Injectable delivery system for heparan-binding growth factors
A method for enhancing chondrogenesis in a subject in need thereof comprises administering to the subject an effective amount of a pharmaceutical composition comprising a growth factor bound to hyaluronic acid (HA)-based hydrogel particles (HGPs). The hyaluronic acid (HA)-based hydrogel particles (HGPs) are conjugated with a heparan sulfate proteoglycan (HSPG). Related medicaments and methods for preparing the medicaments are provided.
US09597409B2 Methods of treating cancer
The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an albumin and b) a platinum-based agent (e.g., carboplatin). The present application also provides methods of treating prostate cancer by administering to the individual a) an effective amount of a composition comprising nanoparticles comprising docetaxel and an albumin; and b) an effective amount of a steroid.
US09597407B2 Targeted antimicrobial moieties
This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.
US09597404B2 Methods and compositions for sustained release of chromium
Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.
US09597403B2 Amino acid conjugates of quetiapine, process for making and using the same
The presently described technology provides a novel class of prodrugs of quetiapine that can be synthesized by chemically conjugating amino acids to quetiapine. The present technology also provides methods of treating patients, pharmaceutical compositions and methods of synthesizing conjugates of the present technology.
US09597399B2 Formulations of bendamustine
Methods of treatment using bendamustine formulations designed for small volume intravenous administration are disclosed. The methods conveniently allow shorter administration time without the active ingredient coming out of solution as compared to presently available formulations.
US09597398B2 Formulations of bendamustine
Methods of treatment using bendamustine formulations designed for small volume intravenous administration are disclosed. The methods conveniently allow shorter administration time without the active ingredient coming out of solution as compared to presently available formulations.
US09597397B2 Formulations of bendamustine
Methods of treatment using bendamustine formulations designed for small volume intravenous administration are disclosed. The methods conveniently allow shorter administration time without the active ingredient coming out of solution as compared to presently available formulations.
US09597394B2 Lectin compositions and methods for modulating an immune response to an antigen
The present invention provides a fusion polypeptide which can bind to a cell surface binding moiety (e.g., a carbohydrate) and serve as a ligand for a cell surface polypeptide, as well as a vector comprising a nucleic acid encoding for such a fusion polypeptide, and a host cell comprising such nucleic acid. The present invention also provides a composition comprising an antigen bearing target and such a fusion polypeptide, as well as a composition comprising a virus or a cell and such a fusion polypeptide. The present invention further relates to a method of modulating an immune response in an animal using such compositions.
US09597393B2 Synthetic toll-like receptor-4 (TLR-4) agonist peptides
The invention provides novel immunological adjuvants and methods for identification of such adjuvants. The invention further provides methods and compositions for eliciting an immune response to an immunogen using the novel adjuvants. The adjuvants can be employed with any suitable immunogen, including proteins, peptides, lipids, and carbohydrates. The immunogen can be derived from a virus, a cancer, or a diseased cell. The elicited immune response can be cellular, humoral, or both.
US09597391B2 Cyclic-dinucleotides and its conjugates as adjuvants and their uses in pharmaceutical compositions
The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants and/or immunomodulators for prophylactic and/or therapeutic vaccination in the treatment of infectious diseases, inflammatory diseases, autoimmune diseases, tumors, allergies as well as for the control of fertility in human or animal populations. The compounds are particularly useful not only as systemic, but preferably as mucosal adjuvants. In addition, the invention relates to its uses as active ingredients in pharmaceutical compositions.
US09597389B2 Oil-in-water emulsion influenza vaccine
The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 μg HA or a low amount such as less than 15 μg HA.
US09597387B2 Targets of Acinetobacter baumannii
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
US09597386B2 Outer membrane proteins of Histophilus somni and methods thereof
The present invention relates to immunological compositions of outer membrane proteins (OMPs) of H. somni, as well as methods of extraction, a respiratory challenge model, methods of administration and diagnostic assays and kits.
US09597384B2 Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
US09597383B2 Formulation and method for preparing specific T cell, and method for preparing the formulation
The present invention provides a formulation and method for preparing specific T cells, and a method for fabricating the formulation is also disclosed. The formulation can induce specific T cell responses, and comprises at least a cell population of dendritic killer cells presenting specific antigens. In addition, the method mentioned above for preparing specific T cells comprises following steps. A T cell population is provided, and then a formulation of preparing specific T cells is mixing with the T cell population. After cultivating, the specific T cells are harvested. Furthermore, the method for fabricating the above formulation comprises the following steps. First, a cell population of dendritic killer cells is provided. A target sample is then provided, and a step of making the cell population of the dendritic killer cells is co-cultivated with the target sample. After co-cultivating, a cell population of dendritic killer cells presenting specific antigens is harvested.
US09597381B2 Methods of preventing rejection of transplanted tissue by administering anti-CD40L antibody and HLA-E-bearing composition
A method is provided for preventing rejection by an immune system of a recipient subject of a tissue transplanted from a donor subject into the recipient subject without the need for long-term administration of non-specific immunosuppressive drugs.
US09597380B2 Terminally modified RNA
The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.
US09597379B1 Protease inhibitor combination with therapeutic proteins including antibodies
Protease inhibitors together with protease sensitive therapeutics or diagnostics are provided, which may be ionically or covalently bound, or unbound. The protease inhibitors and/or protease sensitive moiety may be provided in monomeric, homopolymeric, heteropolymeric (for each of the protease and agent) and/or block copolymeric (combining polymers of agent and inhibitor) form. The inhibitors may be native active or e.g., protease activated. Multiple protease inhibitor peptides may be used in-frame with multiple protease cleavage signals (polymeric protease activated protease inhibitors). Combination with the protease inhibitors with the protease sensitive therapeutic enhances the intact, active molecule local-regional or targeted cell or tissue concentration, peak concentration and/or duration of the therapeutic exposure, thereby increasing its therapeutic efficacy. The protease inhibitors are particularly useful for tumor-targeted therapies and for vaccines.
US09597378B2 Blood coagulation factor VII and VIIa derivatives, conjugates and complexes comprising the same, and use thereof
A blood coagulation factor VII derivative, a blood coagulation factor VIIa derivative, FacVII and FacVIIa conjugates are prepared by linking a polymer capable of extending the blood half-life to the derivative. FacVII and VIIa complexes each prepared by linking a carrier to the conjugate, genes encoding the FacVII and FacVIIa derivatives, expression vectors comprising the genes, transformants introduced with the expression vectors, a method for preparing the FacVII and FacVIIa derivatives using the transformants, a method for preparing the FacVIIa conjugate and complex, a FacVIIa complex prepared by the method, a pharmaceutical composition for the prevention or treatment of hemophilia comprising the derivative, conjugate, or complex as an active ingredient, and a pharmaceutical composition for blood coagulation comprising the derivative, conjugate, or complex as an active ingredient are described.
US09597376B2 Lipoprotein lipase for treatment of hypertriglyceridemic-related conditions including acute pancreatitis
A lipoprotein lipase (LPL) protein for treating and/or preventing HTG and its associated diseases, including but not limited to acute pancreatitis (AP), and in particular, acute pancreatitis secondary to or exacerbated by hypertriglyceridemia, and hypertriglyceridemia and its associated diseases in general, including cardiovascular and metabolic diseases, endocrine disorders, and fat embolism syndrome.
US09597375B2 Coagulation and fibrinolytic cascades modulator
Methods for stopping or slowing bleeding from a wound are provided; these methods include the step of administering a composition comprising a polyphosphate (polyP) to blood from the wound at the site of the wound. Also provided are methods for slowing fibrinolysis and for blocking the action of Tissue Factor Pathway Inhibitor (TFPI) with the use of polyP.
US09597368B2 Peptide and uses therefor
Provided is a method for treatment and/or prophylaxis of a condition associated with T cell mediated chronic inflammatory disease by administration, to a patient, of a peptide comprising N′-SVTEQGAELSNEER-C′ (SEQ ID NO: 1) or an analog of the peptide that inhibits T cell migration. Also provided is the peptide or its analog for use in the methods of treatment and/or prophylaxis of the condition.
US09597363B2 Simian adenoviruses SAdV-36, -42.1, -42.2, and -44 and uses thereof
A recombinant vector comprises simian adenovirus 36, simian adenovirus 42.1, simian adenovirus 42.2 and/or simian adenovirus 44 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses one or more simian adenovirus-36, -42.1, -42.2 or -44 gene(s) is also described. Methods of using the vectors and cell lines are provided.
US09597350B2 Composition comprising at least one alginate for use in treatment and/or prevention of overweight
The present invention relates to a composition in the form of a powder or a viscous paste, and which includes at least one low viscosity alginate having a viscosity of less than about 100 mPaS in a 1 wt % aqueous solution, and at least one high viscosity alginate having a viscosity of more than about 100 mPaS in a 1 wt % aqueous solution. The composition can also include at least one suspending agent. The composition is readily soluble in water such that an aqueous preparation can be prepared without substantive mixing. Also, the aqueous preparation is suitable for use in the treatment and/or prevention of overweight for both therapeutic and non-therapeutic purposes.
US09597349B2 Combination of an oxidant and a photoactivator for the healing of wounds
There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed.
US09597336B2 Therapy for treatment of chronic degenerative brain diseases and nervous system injury
In one aspect, the present invention provides neuroactive steroids for use in the treatment of nervous system disorders, degenerative brain diseases and congenital storage diseases. In a second aspect, the invention provides neuroactive steroids in combination with a Liver X Receptor (LXR) ligand to effect treatment of a nervous system condition.
US09597332B2 Sulfide alkyl compounds for HBV treatment
The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.
US09597331B2 Therapeutic compositions containing macitentan
The invention relates to a product containing the compound of formula (I) below or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having prostacyclin receptor (IP) agonist properties, or a pharmaceutically acceptable salt thereof.
US09597326B2 Benzonapthyridine compositions and uses thereof
The present invention generally relates to compositions comprising benzonapthyridine small molecule immune potentiators (SMIPs) that are capable of stimulating or modulating an immune response in a subject that has had pre- or post-exposure to a pathogen such as hemorrhagic fever virus. Also provided are methods of preparing and using the SMIP compositions of the invention.
US09597325B2 Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics
The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a small-molecule compound of formulas (I)-(XXVI) as disclosed herein to inhibit transcription factor Late SV40 Factor (LSF) for treatment of cancer, e.g., HCC.
US09597324B2 Treatment of CNS disorders associated with mutations in genes encoding lysosomal enzymes
Described is a method for treating an individual having a neurological disorder with an associated mutation or mutations in a gene encoding a lysosomal enzyme. Specifically, the individual is administered a specific pharmacological chaperone for the lysosomal enzyme which increases trafficking of the protein from the ER to the lysosome in neural cells, with or without concomitantly increasing enzyme activity in neural cells. Restoration of trafficking relieves cell stress and other toxicities associated with accumulation of mutant proteins. Restoration of enzyme activity relieves substrate accumulation and pathologies associated with lipid accumulation. In a specific embodiment, the neurological disorder is Parkinson's disease or parkinsonism which is associated with mutations in glucocerebrosidase.
US09597322B2 Otamixaban for use in the treatment of non-ST elevation acute coronary syndrome in patients planned to undergo coronary artery bypass grafting
The invention relates to otamixaban or a pharmaceutically acceptable salt thereof for use in the treatment of non-ST elevation acute coronary syndrome in patients planned to undergo coronary artery bypass grafting.
US09597321B2 Antifibrotic compounds and uses thereof
The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.
US09597316B2 Indole compounds for use in treating inflammation and cancer
Provided herein are compounds, comprising Formula (I) or Formula (II), and their pharmaceutically acceptable salts. Also provided are pharmaceutical compositions comprising a pharmaceutically acceptable excipient and at least one compound of Formula (I) and (II), singly or in combination with other pharmaceutically active ingredients, such as anti-inflammatory agents or anticancer agents. These compounds and pharmaceutical compositions are useful for treating inflammation or an inflammation related disorder in a subject via administration to the subject. These compounds and pharmaceutical compositions are also useful for inhibiting COX-2, for treating cancer, for reducing the size of a neoplasm, and for inhibiting tubulin polymerization in a cell.
US09597315B2 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
The invention provides novel 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including but not limited to depression and anxiety.
US09597314B2 Beta-lactamylalkanoic acids for treating premenstrual disorders
0-lactamyl alkanoic acids are described. Methods for treating various premenstrual disorders using or more β-lactamyl alkanoic acids are also described.
US09597313B2 Composition and methods for the enterosorption and management of toxins
A composition and method for use as a preventive therapy to mitigate the effects of environmental toxins, and particularly aflatoxins in a subject. The subject may be at risk for hepatocellular carcinoma and aflatoxicosis. The composition comprising: an effective amount of an isolated low sodium, calcium aluminosilicate clay in a powder form, wherein the isolated low sodium, calcium aluminosilicate clay contains acceptable levels of dioxins and priority toxic heavy metal contamination, and is capable of preferentially binding aflatoxins in the gastrointestinal tract.
US09597311B2 Suppression and prevention of tumors
Combinations of betaine and vitamin C are used to suppress or prevent malignant tumors, e.g., by combining the two ingredients in a product consumed by a human, dog, or cat, such as an aqueous liquid such as grape juice, the ingredients being provided in containers with instructions for use, or in finished products, especially with support of tests demonstrating the effectiveness of the treatment for, e.g., preventing tumors in populations known to be at risk of developing tumors, or, treating existing cancers in combination with other cancer drugs such as anastrozole and/or fulvestrant and/or artemisinin either concurrently or sequentially to prevent the cancer from growing when the cancer drug is not being used, the combination of betaine and Vitamin C optionally being supplemented or replaced by other treatments like the combination of selenium and Vitamin E or hormone treatments used to slow cancer growth.
US09597309B2 Methods of treating renal disease and other disorders
The invention generally relates to methods of treating a patient suffering from renal disorders or other disorders related to low levels of sRAGE, and/or low levels of adiponectin (e.g., high molecular weight adiponectin) and/or high levels of thrombomodulin, using effective of amounts of a MetAP-2 inhibitor.
US09597306B1 Fumarate compounds, pharmaceutical compositions thereof, and methods of use
Fumarate compounds, pharmaceutical compositions comprising the fumarate compounds, and methods of using fumarate compounds and pharmaceutical compositions for treating neurodegenerative, inflammatory, and autoimmune disorders including multiple sclerosis, psoriasis, irritable bowel disorder, ulcerative colitis, arthritis, chronic obstructive pulmonary disease, asthma, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are disclosed.
US09597304B2 Baclofen formulations and methods for making same
Methods for preparing sterilized baclofen solutions include adjusting the pH to below a desired pH, and steam sterilizing the solution with adjusted pH, which results in the solution having the desired pH. Such solutions may also have low concentrations of 4-CPP. Injectable baclofen solutions having greater than 2 mg/mL baclofen include between 5 mM and 25 mM of a phosphate or sulfate species. The solution has an ionic strength equivalent of about 1.5 M NaCl. The present application also provides baclofen formulations for use in treating spasticity, brain injury, cerebral palsy, spinal cord injury, cervical injury, multiple sclerosis, thoracic injury, or withdrawal symptoms.
US09597295B2 Diene compounds for use in human epidermal cell repair, and pharmaceutical and cosmetic compositions containing them
The present invention relates to a novel use of compounds having the general formula (I): CH3(—CH═CH)n—R  (I) where n=from 2 to 7, and R is chosen from among: CHO, CH2OH, CH2O—CO—R′, CO—OR′, CO—O(−), where R′ is chosen from among H, the alkyl from C1 to C22, each compound of general formula (I) being used as such or in a mixture, as an active principle in a pharmaceutical or cosmetic composition to improve the human epidermal cell repair activity by means of the production of keratin mediated by the cytokeratins cK-19.
US09597293B2 Solid dosage forms comprising an enteric coating with accelerated drug release
The present invention provides a solid dosage form including an inner coating located between a core containing a pharmaceutically active ingredient and an outer enteric coating; wherein the inner coating includes a partially neutralized anionic polymeric material, and at least a carboxylic acid having 2 to 16 carbon atoms the salts thereof or mixtures of the acid and its salt; wherein the outer coating includes an anionic polymeric material which is less or not at all neutralized than the material of the inner coating.
US09597292B2 Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclosed.
US09597291B2 Orally disintegrating tablet containing asenapine
The present invention relates to an orally disintegrating tablet (ODT) containing asenapine maleate and to a process for preparing the ODT. In a first aspect, the present invention relates to an ODT containing asenapine maleate and low substituted hydroxypropylcellulose. In a second aspect, the present invention relates to an ODT containing crystalline asenapine maleate and the ODT is prepared using conventional tabletting techniques as direct compression and granulation. In a third aspect, the present invention relates to an ODT containing asenapine maleate and a carboxylic acid, and to the use of a carboxylic acid for enhancing storage stability of an asenapine maleate containing ODT.
US09597287B2 Edible oral strip or wafer dosage form containing ion exchange resin for taste masking
An edible oral film strip dosage form containing an unpalatable acidic active pharmaceutical ingredient, particularly ketoprofen, and an ion exchange resin as a primary taste masking agent, along with an optional alkaline agent and further optionally containing one or more secondary taste masking agents is provided. The edible oral film strip dosage matrix is formed from at least one water soluble or miscible polymer(s). The optional secondary taste masking ingredients include one or more of flavoring agent(s), sweetener(s), cooling sensation agent(s), and taste receptor blocker(s). The inventive dosages minimize or completely mask the bitterness, burning sensation and throat irritation associated with many acidic active pharmaceutical ingredients. Methods for preparing the inventive edible oral film strip dosage forms are disclosed, as well as their method of administration.
US09597282B2 Cold-warm plaster
A composition for topical application characterized in that it includes, in a hydrogel base, vanillyl butyl ether and menthol. The composition described herein produces an ordered development of cold and warm sensations, obtaining effects that are particularly useful in the treatment of painful disorders of neurological and/or muscular origin. The composition has further moisturizing and soothing effects that concur to an effect that is also curative, i.e., not simply symptomatic, of rheumatic and muscular pain, trauma and bruises. The composition is compatible with each administration form, being preferably and advantageously formulated as a plaster.
US09597281B2 Pharmaceutical formulations useful in the treatment of insomnia
There is provided a formulation suitable for transmucosal administration comprising a short acting hypnotic drug, which formulation provides a measurable plasma concentration of drug within 10 minutes of administration. The formulation is capable of providing sleep on demand, and preferably comprises particles of drug, for example zolpidem or a pharmaceutically-acceptable salt thereof and a mucoadhesion promoting agent, such as sodium carboxymethylcellulose, which particles of drug and mucoadhesive are presented upon the surface of larger carrier particles.
US09597279B2 Anti-aging dermal composition comprising herbal extracts
This application discloses an anti-aging composition for dermal application comprising cannabidiol hemp oil, chuanxiong extract, mondo grass extract, Chinese foxglove extract, female and panax ginseng extract, dragon's blood resin, lilyturf root, and jojoba oil. Other active ingredients may include licorice root, Astragalus membranceus, tree peony, mulberry bark extraction, longan fruit, wild pansy, rose canina seed powder, and Radix polygoni multiflori. The composition is formulated with other components to serve as a cleanser, a moisturizer, a serum, a gel masque, an eye cream, a toner, or an exfoliant.
US09597278B2 Compositions and methods for alleviating hyposalivation and for providing oral comfort
Various compositions and methods are provided to alleviate one or more symptoms associated with hyposalivation and/or xerostomia. Preferred compositions and methods employ one or more plant pulp products and/or a proanthocyanidin at a concentration effective to reduce or eliminate the symptoms. Especially preferred product components are isolated from a fruit and/or seed (e.g., grape, cranberry, blue berry, black berry, etc.), and where a second component is is preferably a freeze-dried pulp from a citrus fruit (e.g., lemon, orange, lime, grapefruit, tangerine, mandarin orange, ugli fruit, etc.) not containing peel or juice therein.
US09597276B2 Composition for the prophylaxis of candidiasis
The invention solves the problem of the practical realization of an effective prophylactic composition which uses available and safe components and which can be recommended for preventing the growth of candidiasis of the skin and/or mucous membranes in humans in the following risk group: sufferers of diabetes mellitus, people with blood diseases, immune deficiency and other serious pathologies, patents after a course of hormone therapy, antibiotic treatment or chemotherapy, as well as for babies and pregnant women; and for people using tooth implants. The composition for the prophylaxis of candidiasis comprises active components, with the active components used being xylitol in a quantity of 0.3-20.0% by mass and sodium or potassium alginate or a mixture thereof in a quantity of 0.01-2.0% by mass, as well as inert components.
US09597274B2 Peptides and their use in the treatment of skin
Peptides (and derivatives thereof), topical compositions, and methods of diminishing signs of aging and/or improving health of human integuments are provided. The peptides are derived from human Growth Differentiation Factor 11 (GDF-11).
US09597271B2 Cosmetic compositions and methods
A cosmetic composition for topical application to skin is provided. The cosmetic composition includes vitamin B3 compound, a ricinoleate compound and a dermatologically acceptable carrier. The vitamin B3 compound and the ricinoleate beneficially or even synergistically up-regulate proteasomal protease activity as evidenced by a higher observed net luminescence value relative to the calculated net luminescence value in B16 melanoma cells.
US09597269B2 Surface-treated powders and cosmetic compositions in which such powders are mixed
The invention is directed to the cosmetic powder surface-treated with a silicone gel, wherein the surface treatment with the silicone gel affords excellent water repellency, the exhibits smooth and light touch, and affords moist usability peculiar to the silicone gel and excellent adhesion to skin for the cosmetic powder. The powder is an inorganic powder, an organic powder or a composite powder thereof. The silicone gel is obtained by hydrolysis and condensation reacting an organopolysiloxane containing at least a diorganopolysiloxane having reactive opposite ends shown in the following formula (1) and a silane coupling agent having the following formula (2) with at least two hydrolyzable groups in one molecule or a reactive polysiloxane of the following formula (3) as a crosslinking agent. (1) R1R22SiO—(R22SiO)L—SiR1R22; (2) R3R4nSiX(3-n); and (3) R53SiO—(R52SiO)n-SiR53.
US09597268B2 Surface-treated and plate-like powder for cosmetic compositions and solid powdery cosmetic composition blended therewith
A plate-like powder for cosmetics, powder is surface treated with a silicone gel, enhancing moldability and impact resistance of a solid powdery cosmetic composition as well as a solid powdery cosmetic composition. The surface-treated powder exhibits smooth and light touchiness, has moist usability, and excellent adhesion to skin. The surface-treated powder is blended into a powdery cosmetic composition, enhancing moldability and impact resistance of the composition and removed by an applicator. The powder is an inorganic powder, an organic powder or a composite powder, and silicone gel is obtained by hydrolyzing and condensing an organopolysiloxane containing at least a diorgano polysiloxane having reactive opposite ends by the following formula (1) and either a silane coupling agent of the following formula (2) having at least two hydrolyzable groups per one molecule or a reactive organo polysiloxane having the following formula (3) as a crosslinking agent R1R22SiO—(R22SiO)L—SiR1R22  (1) R3R4nSiX(3-n)  (2) R53SiO—(R52SiO)n-SiR53  (3).
US09597266B2 Gel composition for external application containing an adenine compound
An object of the present invention is to provide a composition for external application that is applied to a part of the skin to more effectively elicit the useful effects of an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine, and that has long-lasting effects and enhanced skin-moisturizing effects. A gel composition for external application containing an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine is prepared by using agar as a gelling agent. The gel composition is further prepared in the form of a sheet-like adhesive patch. The gel composition in the form of a sheet-like adhesive patch is kept immersed in an aqueous solution containing the adenine compound.
US09597264B2 Reversible dental adhesive
A method of removing a dental adhesive may comprise locating the position of the dental adhesive, directing radiant energy into the dental adhesive causing the dental adhesive to weaken a bond formed with the dental adhesive, and breaking the bond by applying a suitable force to overcome the weakened bond. A dental adhesive may comprise a polymer and a dye or pigment, The dental adhesive may be formulated to cure to form a bond that is weakened in response to the dye or pigment absorbing radiant energy subsequent to curing.
US09597263B2 Fluid and nutrition delivery device and method of use
A gastric feeding tube and method of use where the tube is of sufficient length for insertion into an esophagus of a subject via the nose or mouth. The gastric feed tube comprises a tube having a distal portion, a middle portion and a proximal portion, an outer surface and an inner surface forming a wall of the tube having a thickness and wherein the wall of the tube defines a lumen of a defined geometry, the lumen having an opening at a distal end of the tube for positioning in a stomach or jejunum of the subject and an opening at the proximal end of the tube for positioning outside of the nose or mouth of the subject wherein the lumen extends longitudinally through the tube connecting the opening at the distal end of the tube and the opening at the proximal end of the tube. The defined geometry of the lumen has a transverse major axis and a transverse minor axis that are perpendicular and wherein a portion of the inner surface of the wall of the tube along the transverse major axis comprises a rib that protrudes into the lumen and thickens the portion of the inner surface of the wall of the tube. The rib prevents the tube from fully collapsing and blocking the lumen when the tube is in use under normal conditions.
US09597262B2 Medication administration tracker
A medication administration tracker is provided. The medication administration tracker includes a medication container, such as an IV bag, vitamin organizer, prescription bottle and the like. If the present invention is a prescription bottle, a lid is releasably securable to the bottle. The present invention may include at least one indicator configured to produce an indication when prompted. A time keeper and a processor are integrated into the lid. The time keeper keeps time and the processor is operatively connected to the indicator and the time keeper. The processor is programmable to receive at least a dosage time and activate the indicator when the time keeper reaches the dosage time.
US09597258B2 Pressurized manifold and jet system for a spa
A spa according to the present invention includes a shell having a plurality of seating positions formed in the shell, a base supporting the shell, and a hydrotherapy system configured to draw a fluid from the spa and inject the fluid back into said spa as at least one a pressurized jet. The hydrotherapy system includes a pump for circulating the fluid and a jet pod arranged in at least one of the seating positions and in fluid communication with the pump.
US09597257B2 Automated chest compression apparatus
A system applies cardiopulmonary resuscitation (CPR) to a recipient. An automated controller is provided together with a compression device which periodically applies a force to a recipient's thorax under control of the automated controller. A band is adapted to be placed around a portion of the torso of the recipient corresponding to the recipient's thorax. A driver mechanism shortens and lengthens the circumference of the band. By shortening the circumference of the band, radial forces are created acting on at least lateral and anterior portions of the thorax. A translating mechanism may be provided for translating the radial forces to increase the concentration of anterior radial forces acting on the anterior portion of the thorax. The driver mechanism may comprise a tension device for applying a circumference tensile force to the band. The driver mechanism may comprise an electric motor, a pneumatic linear actuator, or a contracting mechanism defining certain portions of the circumference of the band. The contracting mechanism may comprise plural fluid-receiving cells linked together along the circumference of the band. The width of each of the fluid-receiving cells becomes smaller as each cell is filled with a fluid. This causes the contraction of the band and a resulting shortening of the circumference of the band.
US09597253B2 Method and apparatus for the treatment of amblyopia
A method for the treatment of amblyopia comprising the steps of diagnosis and approval of a patient by a medical practitioner, providing access to an eye-training platform for the approved patient and instructions to the approved patient on using the eye-training platform, preparation of a therapy protocol by the medical practitioner, use of the eye-training platform according to the therapy protocol, recordal of patient results, intermediate examination of the patient and review of patient results, further use of the eye-training platform according to a modified therapy protocol, recordal of further user results, and examination of visual acuity and review of user results by the medical practitioner.
US09597252B2 Tactile plate assembly
A tactile plate assembly used as a tactile warning device on walkways comprises a plurality of tactile plates with texture for providing tactile awareness. A bracket connects first and second tactile plates to each other. The brackets include holes of sufficient size to allow a substrate such as concrete or asphalt to flow therethrough to anchor the tactile plate assembly in place.
US09597250B2 Posture rehabilitation apparatus
Posture apparatus for rehabilitating alterations of the locomotor system includes a rectangular-shaped platform offering housing to two portions and receive a subject user, each portion respectively including a base reversibly respectively fixed to its corresponding portion and adapted to respectively support a support matching the left foot and a support matching the right foot of the subject; a belt with elastic band adapted to be worn by the subject; at least one elastic cord for connecting the belt with support elements present on the apparatus; at least two telescopic rods adapted to fix at a predetermined height the support elements; the apparatus conferring to the anatomic structures involved in the exercise, and to the feet of the subject, a high number of degrees of freedom of movement, with the matching feet supports divided into two transverse portions which allow the foot to perform a natural helical movement.
US09597249B2 Body containment construction suitable for use within bio-cremation processes
Body containment constructions, materials, and methods of use for bio-cremation processes are disclosed. Preferably, the containment constructions of the present invention provide the functionality of liquid containment and also the functionality of body presentment for viewing purposes, if desired, in addition to bio-degradability. Advantageously, liquid containment is provided in a body containment construction that is sufficiently liquid impervious, allows for body transport by sufficient structural support, and is decomposable within the time period for a bio-cremation process. More preferably, the containment construction will dissolve or decompose within a normal procedural time period without leaving any component remaining from the containment construction. According to an aspect of the present invention, a body containment bag is provided that is made from a structural material that is combined with a liquid containment material and one or more closures, wherein the body containment bag is effectively usable for bio-cremation during which all components of the body containment bag can effectively decompose by alkaline hydrolysis. Methods of making and of utilizing a body containment bag for decomposition are also disclosed.
US09597248B2 Casket system including rollers and height adjustment mechanism
A casket system includes a casket container and a height adjustment mechanism. The casket container has a bottom, a head end panel, a foot end panel, and rollers supported by the bottom. The height adjustment mechanism includes a threaded shaft, a worm nut, and a crossbar. The threaded shaft extends at least partly in the vertical direction. The shaft is rotatably coupled to the casket container proximate the head end panel. The worm nut is rigidly secured to the crossbar. The worm nut rotatably engages the threaded shaft and translates rotational movement into axial movement along the shaft. The crossbar includes spaced-apart extensions extending from an edge thereof away from the head end panel. The spaced-apart extensions are configured to contact and engage a casket insert that is sized and configured to receive a deceased. The axial movement of the worm nut causes the crossbar to move vertically with respect to the head end panel.
US09597246B2 Premature neonate closed life support system
A premature neonate closed life support system (NCLSS) including: at least one chamber confining a cradle-like neonate support (CLNS) having suitable dimensions and geometric-configuration for accommodating at least one premature neonate having at least two operational configurations, said operational configurations comprising: a first operational OPEN configuration whereby said CLNS is adapted to couple said neonate to at least one life supporting system by means of at least one life supporting coupling line, prior to positioning said CLNS in a medical device; and a second operational air-tight CLOSED configuration whereby said neonate remains continuously coupled to said at least one life supporting system by means of at least one life supporting coupling line, when positioning said CLNS within said medical device. The OPEN and CLOSED configurations are reversible.
US09597243B1 Medical procedure chair
A medical procedure chair that includes a sitting area, a sliding seat back section, and a living hinge connecting the sitting area of the chair to a sliding seat back.
US09597240B2 Vehicle accessibility system
An accessibility system for providing access into or out of a vehicle includes a pan defining a securement area. The pan includes a first end, a second end, and a support surface. A ramp assembly includes a first segment and a second segment hingedly coupled to the first segment. The ramp assembly is pivotally coupled to and deployable from the pan near the second end. A tailgate assembly is detachably secured and pivotally coupled to the pan such that during deployment of the ramp assembly, the ramp assembly is pivotable about a first axis and the tailgate assembly is pivotable about a second axis parallel to and offset from the first axis.
US09597236B2 Absorbent core exhibiting controlled deformation in use and absorbent article comprising said core
An absorption body intended to form part of an absorbent disposable article includes a first absorption layer intended to face towards the user upon use and a second absorption layer intended to face away from the user upon use. The first absorption layer has a longitudinal opening in the crotch area and the second absorption layer has a longitudinal compression arranged in the crotch area.
US09597235B2 Methods and apparatuses for rejecting defective absorbent articles from a converting line
The present disclosure relates to methods and apparatuses for rejecting defective absorbent articles from a converting line. At a downstream portion of a converting process, a continuous length of absorbent articles may be subjected to a final knife and cut to create discrete absorbent articles advancing on a first carrier. From the first carrier, the discrete absorbent articles may be transferred to a transfer apparatus, which in turn, transfers the discrete absorbent articles to a second carrier. The transfer apparatus may include carrier members that orbit around an axis of rotation and may be adapted to receive the absorbent articles from the first carrier and transfer the absorbent articles to the second carrier. Defective absorbent articles may be detected by an inspection system, which may be operably connected with the transfer apparatus and/or the first carrier to remove the defective absorbent articles from the converting process.
US09597233B2 Adapted compression/splint orthosis for reinforcement of the calf musculoanoneurotic pump
An orthosis (10) has an elastic compressive distal portion (14), extending upwards from the ankle, associated with an adjacent rigid splint proximal portion (16), enveloping the region of the calf between the level of the point where the Achilles tendon joins the calf muscles and the level located below the tibial tuberosity. This rigid splint proximal portion (16) is an essentially non-elastic, deformable tubular portion, made by: placing the orthosis onto a template representative of the morphology of the patient's calf; applying in situ on the orthosis, in the region of the splint proximal portion, a hardenable biocompatible resin; hardening the resin with the orthosis maintained on the template; and removing the orthosis in its finished state.
US09597230B2 Devices and methods for glaucoma treatment
Intraocular implants and delivery instruments are disclosed for treating ophthalmic conditions and ocular disorders, such as glaucoma. The implants are configured to extend between the anterior chamber of the eye and a fluid outflow path or physiologic outflow pathway, such as Schlemm's canal, of the eye for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The implants can have features for anchoring the implant into the physiologic outflow pathway as well as preventing the walls of the physiologic outflow pathway from closing the outlet of the implants. The delivery instruments can be steerable so as to make implantation easier. Additionally, the delivery instruments can be configured to hold a plurality of implants so that multiple implants can be implanted through one incision without removing the delivery instrument from the incision between serial implantations.
US09597224B2 Deployment actuation system
Contraceptive methods, systems, and devices generally improve the ease, speed, and reliability with which a contraceptive device can be deployed transcervically into an ostium of a fallopian tube. The contraceptive device may remain in a small profile configuration while a sheath is withdrawn proximally, and is thereafter expanded to a large profile configuration engaging the surrounding tissues, by manipulating one or more actuators of a proximal handle with a single hand. This leaves the other hand free to manipulate a hysteroscope, minimizing the number of health care professional required to deploy the contraceptive device.
US09597223B2 Reversible acute occlusion implant, delivery catheter and method
A permanent reversible acute occlusion implantable device and method are described for immediate occlusion of a body lumen, such as the fallopian tubes of the human female, but which can be reopened when necessary at a later date.
US09597220B2 Apparatus and methods for correcting nasal valve collapse
The present invention relates to apparatus ad methods for correcting nasal valve collapse comprising a device configured for suspending a nasal valve, the device comprising a body portion comprising a proximal end, a distal end, and a plurality of barbs, wherein the body portion is configured to be inserted through or underneath the upper lateral cartilage of a patient and wherein the plurality of barbs are configured to engage a soft tissue overlying a bony tissue proximal to the upper lateral cartilage, and a head portion coupled to the proximal end of the body portion wherein the head portion is configured to engage the upper lateral cartilage of the patient when the plurality of barbs are engaged with the soft tissue overlying the bony tissue proximal to the upper lateral cartilage.
US09597218B2 Systems and methods for limb support
An orthotic device according to embodiments of the present invention includes a substantially rigid internal footbed with an external rocker bottom, two struts rigidly coupled to the footbed, a paddle coupled to each strut, each paddle having an inner surface configured to face a limb of a patient, and a strap system configured to interface with the paddles for tightening around the limb, the inner surfaces of the paddles including a plurality of protrusions configured to minimize sliding of the first and second paddles with respect to the limb or with respect to a cast applied to the limb. The orthotic device may include two or more support layers on the footbed, each layer having a support aperture larger than and at least partially overlapping the support aperture below.
US09597217B2 Cable driven joint actuator and method
A cable driven actuator and actuator method involve a movable link that is movable about a path by a cable connected to the link, and a movable support member having a cable routing element. The support member is movable in a manner to change a moment arm of the cable acting on the link to control torque applied to the joint.
US09597215B2 Transpyloric anchoring
A gastrointestinal implant device comprises a planar proximal element configured to reside in a stomach to resist distal migration, a distal element configured to reside in an intestine to resist proximal migration and one or more tethers coupling the planar proximal element to the distal element.
US09597213B2 Handle mechanism for actuating delivery catheter
A handle for delivering, from a distal end of a catheter, a stent positioned within a sheath. The handle comprises an upper rack fixed to the handle and an upper distal block moveable along the upper rack and defining a pawl configured to permit only proximal movement in relation to the upper rack, further including an upper proximal block moveable along the upper rack and defining a pawl configured to permit only proximal movement in relation to the upper rack. The handle includes a lower rack configured to slide proximally and, alternatingly, distally in relation to the handle.
US09597209B2 Vascular endograft
An endograft includes a main body having a wall separating interior and exterior surfaces and adapted to be inserted within the vessel. The main body is characterized by a single proximal opening and two distal openings and at least one aperture extending through the wall. At least one stent is secured to the main body that upon expansion pressure fits the main body into the vessel. An open tunnel is secured to the interior surface of the main body around the main body aperture and secured somewhere along the tunnel length to provide fluid communication between the interior and exterior surfaces of the main body through the aperture and with the vascular branch in proximity to the main body aperture. The insertion of a sleeve positioned partly within the tunnel and extending beyond the exterior surface of the main body into the vascular branch assures to the vascular branch.
US09597208B2 Side branched endoluminal prostheses and methods of delivery thereof
An expandable prosthetic device and method of delivery that allows the initial placement of multiple guidewires into selected target sites. The prosthesis includes a main body device. This main body device has a separate side branch guidewire lumen that passes through the main body device and through a side opening in the main body device. As the main body device is advanced, the side opening is self guided (by the side branch guidewire) and self-aligns to the side branch vessel ostium. The main body device is then deployed, leaving the side branch guidewire in place. A side branch device is then advanced along the side branch guidewire through the main body device, through the side wall opening and into the native side branch vessel. The side branch device can then be deployed to engage the main body device and the native side branch vessel.
US09597204B2 Branched stent-graft system
An endovascular stent-graft (10) includes a generally tubular hourglass-shaped body (22), which is configured to assume a radially-compressed delivery configuration and a radially-expanded deployment configuration. The hourglass-shaped body (22) includes a flexible stent member (26), which includes a plurality of structural stent elements (28); and a tubular fluid flow guide (24), which includes a fabric (29), and is attached to the structural stent elements (28). The hourglass-shaped body (22) is shaped so as to define a narrow waist portion (32) longitudinally surrounded by and adjacent to wider first and second longitudinal portions (30, 34). The fabric (29) along the waist portion (32) is shaped so as to define at least first and second lateral apertures (36, 38). Other embodiments are also described.
US09597189B2 Prosthetic tibial component for knee joint prosthesis
A prosthetic tibial component for a knee joint, said prosthetic tibial component comprising: a base construct for engaging the tibia; and a bearing construct for engaging the femoral side of the knee joint; said bearing construct being adjustably fixedly mountable to said base construct.
US09597188B2 Version-replicating instrument and orthopaedic surgical procedure for using the same to implant a revision hip prosthesis
A modular femoral prosthesis for use during performance of a hip revision procedure includes a proximal body component, a distal stem component, and a locking bolt. Surgical instruments and methods for use in implanting such a modular femoral prosthesis are disclosed.
US09597183B2 Delivery system for vascular implant
A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.
US09597173B2 Anti-obesity dual stent
The anti-obesity dual stent includes a tubular outer structure within which is located a coaxial tubular inner structure. The outer structure is sized to fit within a duodenum in substantially coaxial relation therewith. The outer and inner structures communicate with the pylorus and papilla of Vater to provide conduits for the chyme and digestive fluid. Alternatively, the anti-obesity dual stent may include a tubular papilla-supplied structure which has a lateral orientation relative to a tubular pylorus-supplied structure. The papilla-supplied and pylorus-supplied structures each are sized to fit longitudinally within the duodenum. The pylorus-supplied and papilla-supplied structures communicate with the pylorus and papilla of Vater to provide conduits for the chyme and digestive fluid.
US09597169B2 Brushhead for a power toothbrush with a two position coupling assembly
The replaceable brushhead, used for a power toothbrush, includes a neck portion (22) having a hollow part located at a proximal end thereof. The brushhead assembly includes a bristle portion (18) at a distal end of the neck portion. A connecting assembly (20) is positioned within the hollow portion of the neck, the connecting assembly having two distinct, mechanically stable, positions. In the first position, the connecting assembly has a first physical arrangement in which the brushhead assembly is conveniently removable or insertable onto an output shaft (16) from a handle portion of the power toothbrush. In the second position, the connecting assembly has a second physical arrangement, in which a portion of the connecting assembly makes physical contact with the output shaft such that the force or torque produced by the output shaft in operation is transferred to the brushhead assembly for movement thereof.
US09597167B2 Implant
The present disclosure relates to an implant, such as a dental implant, having a base member and a thread arranged at an outer end of the base member. The dental implant can be easily inserted and good footing of the implant in the bone can be achieved. Annular ridges and/or recesses can be formed in a section of the base member having no thread.
US09597166B2 Orthodontic appliance with encoded information
An improved edgewise orthodontic bracket is disclosed. In one embodiment, a bracket has a single pair of opposing T-shaped tie wings which define an archwire slot therebetween. Notches are provided on each of the mesial and distal sides of the center leg of each T-shaped tie wing for selectively receiving a ligating device. The notches are defined in the gingival/occlusal edges of the tie wings and comprise sloped portions that extend labially towards the archwire slot. Convex sidewall portions and convex floor portions are provided in the archwire slot adjacent to the notches. The body of the bracket is interconnected to a base that may includes a continuous series of characters that serve as texturing to facilitate bonding of the bracket with a tooth. A discontinuous perimeter rail may be used at the edge of the base.
US09597165B2 Method, system and model for indirect bonding
A physical model of at least a portion of a patient's dentition has model dental surfaces corresponding to real dental surfaces of the patient's dentition. The physical model includes one or more targets, each configured for facilitating placement of an orthodontic appliance on the model at a desired location. The targets lack mechanical stops that are outwardly protruding from the original model dental surfaces. Also provided are a method of manufacturing a physical model for use in indirect bonding procedures, a method for indirect bonding for use in an orthodontic procedure, a method for providing an indirect bonding transfer tray for use in an orthodontic procedure, and a system for providing a physical model for use in indirect bonding orthodontic procedures.
US09597163B2 Tooth positioners, method and apparatus for making the same, and method of positioning teeth using the same
A method and apparatus form a tooth positioner for repositioning at least one tooth of a patient and provide a dental arch cast of a patient, separate at least one tooth from the dental arch cast, fix a pin in a stump part of the at least one separated tooth, and in any non-separated teeth, reconstruct the dental arch cast of the patient by aligning the separated teeth to correspond to the alignment in the patient's mouth and hold the pins in a material that may be softened, soften the material, apply force to the pin fixed in the at least one tooth to be repositioned to move it in a desired direction to obtain a realigned arch, and form a tooth positioner corresponding to the realigned arch. The tooth positioner is used by having the patient wear it for a period of time.
US09597155B2 Radiopaque material for enhanced X-ray attenuation
A medical device that may be implanted in a patient's body is disclosed. An illustrative medical device has an elongated structure that includes a material loaded with a radiopaque material. The radiopaque material includes radiopaque particles having multiple sets of radiopaque particles. The multiple sets of radiopaque particles may include a first set of radiopaque particles having particles with particle sizes in a first particle size range and a second set of radiopaque particles having particles with particle sizes in a second particle size range. The second set of radiopaque particles may have particles configured to fit within interstitial spaces between particles of the first set of radiopaque particles.
US09597150B2 Method for the permanent removal of hair
The invention encompasses a method of inhibiting the growth of hair in skin including epilation of follicles in the skin, waiting until within 5 days of the commencement of metanagen, applying a photodynamic agent to the skin, and exposing the skin to photoactivating light.
US09597147B2 Methods and systems for treatment of tissue in a body lumen
A system for measuring physiologic characteristics or treating tissue in a body lumen. The system may be used for treating abnormal mucosa in the esophagus. The system comprises an energy delivery device, such as an ablation device including an electrode support and an electrode pattern on the support. The ablation device may expand in size from a pre-deployed state to a deployed state. The system may include a sizing device having an inflatable balloon on a distal end of a catheter that is inflated with an expansion medium to expand the balloon to engage the wall of the esophagus so that the internal cross-section can be calculated or measured. The sizing device may also a controller for delivering an expansion medium and measuring the amount and pressure of the expansion medium inside the catheter. Methods of treating or diagnosing tissue are also disclosed.
US09597145B2 Non-thermal ablation system for treating tissue
Systems and methods for non-thermal ablation of tissue are provided. A non-implantable minimally invasive system for treatment of tissue in a body via direct current ablation is provided including a catheter, a plurality of electrodes for deployment through the catheter, a power source for applying power to the electrodes, and a fixation element for maintaining the catheter in a treatment position during treatment of the tissue. A minimally invasive method for treating tissue in a body via direct current ablation is provided including inserting a catheter into the body such that a portion of the catheter remains outside of the body, deploying a fixation element to fix the catheter in a treatment position, deploying a plurality of electrodes through the catheter, applying power to the plurality of electrodes, using the electrodes to apply a current to the tissue, and removing the catheter from the body.
US09597143B2 Sterile medical instrument charging device
A system includes a medical device and a charging device. A sterile barrier may be interposed between the medical device and the charging device. The medical device includes an integral power source and an active element. The charging device is configured to charge the integral power source. The charging device may charge the integral power source through direct contact between features of the charging device and features the medical device. The charging device may alternatively charge the integral power source wirelessly, such as through inductive coupling. The medical device may include conductive prongs that are retained by the charging device. The charging device may physically couple with the medical device via magnets. The medical device and the charging device may be provided together in a sterile package as a kit. The kit may also include a reclamation bag to facilitate reclamation of electrical components.
US09597142B2 Method and system related to electrosurgical procedures
Electrosurgical procedures. At least some of the example methods that include: supplying energy to an active electrode of an electrosurgical wand, the supplying energy to the active electrode by an electrosurgical controller; monitoring an electrical parameter associated with the energy; and determining, based on the electrical parameter, the presence of a wand condition of the electrosurgical wand, the wand condition being at least one selected from the group consisting of: a surface area of the active electrode is less than a predetermined threshold surface area; the surface area of the active electrode is approaching the predetermined threshold surface area; and that the electrosurgical wand is affected by a blockage.
US09597138B2 Motorized bone cement mixing and delivery system with an enlarged connector for connecting to the cannula through which the cement is injected into the patient
A bone cement mixing and delivery system including a mixer, a delivery device, and a flexible extension tube. A connector is attached to a distal end of the flexible tube. The connector includes a housing, a fitting and an enlarged knob. A spindle that extends through the housing connects the fitting to the knob so the fitting rotates with the knob. A cannula is connected to the mixing and delivery system by placing the cannula fitting adjacent the connector fitting. The knob is rotated to result in the like rotation of the connector fitting. This causes the complementary threading on the connector fitting and the cannula fitting to engage.
US09597137B2 Catheter with integrated cement delivery balloon
A bone filling device includes a catheter that defines a longitudinal axis and extends between a proximal end and a distal end. A first lumen extends along the longitudinal axis of the catheter and defines a first passageway. A second lumen extends along the longitudinal axis of the catheter and defines a second passageway. An inflatable body includes a wall that defines a fillable cavity. The fillable cavity is in fluid communication with the first passageway. A bone filler delivery port continuous with the second passageway and configured to dispense bone filling material.
US09597136B2 Apparatus for reinforcing bone and tools for mounting the same
An apparatus, for reinforcing bone and tools for mounting the same, has an implant including a barrel and a device. The implant can be expanded by an expanding apparatus including an outer tub, a base, a hollow body and a handle. The expanding apparatus can be bound to the implant to place the implant into a bone to be treated and adjust the expansion degree. The expanding apparatus can be replaced by an injector apparatus including a container for bone cement and an injecting handle. The injector apparatus can inject a mixture for reinforcing bone (e.g., bone cement) into the bone through an exit, the device, the aperture, the barrel and the window of the barrel, and into the to-be treated area.
US09597130B2 Bone fixation system including K-wire compression
A bone fixation system includes a bone plate, bone anchors, temporary fixation members, and forceps. The temporary fixation members are configured to be inserted through apertures in the bone plate and into underlying bone segments that are separated by a bone gap. The forceps are configured to apply a force to the temporary fixation members that causes at least one of the underlying bone segments to translate with respect to the other bone segment, thereby reducing or distracting the bone segments without interfering with final fixation by screws of bone segments.
US09597127B2 Instruments and methods for stabilization of bony structures
The present invention relates to a brace installation instrument placement that is mounted to anchors secured in an animal subject. The installation instrument includes anchor extensions coupled to the anchors. The instrument is movable with respect to the anchors to position a brace in a position more proximate the anchors. The brace can be indexed for insertion at a predetermined orientation with respect to the installation instrument. Methods and techniques for using the installation instrument are also provided.
US09597123B2 Clivus plate
The present disclosure generally relates to a fixation device for positioning and immobilizing at least two adjacent vertebrae. In particular, in one or more embodiments, the present disclosure relates to an anterior clivus plate that immobilizes at least two adjacent vertebrae.
US09597115B2 Ring sealing apparatus for trocar and trocar
A rotary structure having a large upper part, a small middle part and a large lower part is formed between guiding blocks (11) of a guiding mechanism (1). A positioning groove (10) is disposed at the wasp-waist of the guiding block (11). The bottom of a sealing ring (3) is embedded in the positioning groove (10) to surround the guiding block (11). When a surgical instrument is inserted, the sealing ring (3) confined within the positioning groove (10) extends out of the gap between the guiding blocks (11) to surround the instrument. The contact area between the sealing ring (3) and the instrument provides a guiding function to different forms of surgical instrument and transforms a “soft-hard” friction area between the sealing ring (3) and the instrument into a “hard-hard” friction area between a plastic guiding surface of the guiding blocks (11) and an outer metal sheath of the instrument.
US09597113B2 Endoscope and shaft system
An endoscope and shaft system include an access shaft and an endoscope which can be inserted into the access shaft, the proximal end of the access shaft has a grip part, and the endoscope is held in a connecting piece. The connecting piece can be detachably connected to the grip part, and the connecting piece can be rotated about the longitudinal axis of the endoscope relative to the grip part when the connecting piece is connected to the grip part.
US09597110B2 Tissue-removing catheter including operational control mechanism
A tissue-removing catheter includes a sensor configured to detect a parameter of the catheter during the cutting operation of the catheter when a tissue-removing element is in a tissue-removing position. A locking control circuit is in electrical communication with the sensor and a locking device. During an operational control function, the locking control circuit receives a signal from the sensor based at least in part on the parameter of the catheter detected during the cutting operation of the catheter. The locking control circuit determines whether the received signal is indicative of a tissue-removing element engaging a non-tissue obstruction. The locking control circuit configures the locking device in its locked configuration to inhibit movement of the tissue-removing element from its tissue-removing position to its neutral position if the received signal is indicative of the tissue-removing element engaging a non-tissue obstruction.
US09597108B2 Manual thrombectomy device
Disclosed are manual thrombectomy devices having a plurality of elastic wires to form one or more cages and/or soft brushes connected to a lumen shaft along a longitudinal direction to easily detach thrombi from a vessel wall by manually rotating the lumen shaft right and left. And without any extra inflow tube, the manual thrombectomy device has an aspiration lumen and an inflow lumen in one body of the lumen shaft not only for preventing occurrence of a vacuum or a low pressure state in the blood vessel due to the thrombi aspiration during operation, but also for cleaning the vessel wall through outflow holes and for excreting the thrombi through aspiration holes.
US09597105B2 Vibrating surgical instruments for blunt dissection
A dissector including a body, a first arm, a second arm, and a string. The first arm extending from the body towards a distal end thereof and the second arm extending from the body towards a distal end thereof. One end of the string is coupled to the first arm adjacent the distal end thereof and the other end of the string is coupled to the second arm adjacent the distal end thereof. The first and second arms have an expanded configuration such that the string is taut and have a collapsed configuration such that the string is slack. The string is configured to dissect tissue when the first and second arms are in the expanded configuration. The string may oscillate to dissect tissue. The distal ends of the first and second arms may atraumatically dissect tissue.
US09597104B2 Handheld surgical handle assembly, surgical adapters for use between surgical handle assembly and surgical end effectors, and methods of use
The present disclosure relates to a surgical device including an adapter assembly for selectively interconnecting an end effector and the device housing. The adapter assembly includes at least one drive converter assembly that converts and transmits a rotation of the rotatable drive shaft to an axial translation of at least one axially translatable drive member of the end effector. A first drive converter assembly includes a first drive element, a nut, an articulation sleeve, an articulation bearing, and an articulation link. Rotation of the rotatable drive shaft results in rotation of the first drive element. Rotation of the first drive element results in axial translation of the nut, the articulation sleeve, the articulation bearing, the articulation link, and the at least one axially translatable drive member of the end effector.
US09597103B2 Ultrasound based method and apparatus for stone detection and to facilitate clearance thereof
Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.
US09597097B2 X-ray based cutblock positioning jig
A cut block positioning jig including a first alignment member, a second alignment member, and both first and second guide members. The first alignment member is movable towards and away from a patient's bone to which the positioning jig is mounted to arrange the jig at a predetermined position relative to the bone based on x-rays of the patient. The second alignment member is movable towards and away from the bone to arrange the jig at the predetermined position relative to the bone. The first and second guide members are configured to direct cut block support members to the bone to couple a cut block to the bone to provide the bone with patient-specific cuts.
US09597095B2 Screw guide and tissue retractor instrument
An apparatus is provided for performing spinal surgery having a handle assembly, a screw guide, and a retractor. A shaft is provided with a handle, a neck portion and a connecting portion. The screw guide is provided with a connecting element coupled to the connecting portion of the handle assembly. A retractor for retracting tissue is coupled to the screw guide, wherein the neck portion of the handle assembly is provided with a spring loaded sleeve adapted to engage one of a plurality of holes positioned on a portion of the connecting element. The connecting portion is pivotably coupled to the connecting element.
US09597093B2 Temporarily fixable angled drill
A drive tool has a tubular drive shaft extending along a first axis with a first end of the shaft defining a connector element including a part-spherical cavity. A second end of the shaft has a drive element. The connector element has walls surrounding the part-spherical cavity, and a pair of slots extending along the walls of the connector element between an outer surface of the connector element and the cavity. A drive element extends along a second axis having a driver tool at a first end and a part-spherical head at a second end, the head pivotally mount in the part-spherical cavity in the connector element. A pair of deflectable arms which engage the part-spherical head are mounted adjacent the cavity of the tubular drive shaft and are deflectable through the slots onto the part-spherical head.
US09597092B2 Mechanized surgical equipment comprising an instrument and an instrument holder, corresponding packaging and instrument holder
A piece of mechanized surgical equipment is provided, which includes an instrument holder having an element for receiving and retaining a surgical instrument for mechanized use. Also provided is a surgical instrument for mechanized use and configured to be mounted on the instrument holder. The element for receiving and retaining is mobile between an unlocking position, in which the element enables insertion of the instrument into the instrument holder or withdrawal thereof, and a locking position, in which the element prevents the withdrawal of the instrument from the instrument holder. Furthermore, the equipment includes a case in which an active blade of the instrument can be removably housed, the case having an engaging element for engaging with the receiving and retaining element so as to cause the element to move from the unlocking position to the locking position, or vice versa.
US09597091B2 Articulated bone drill and tap
Technologies related to articulated bone drill and articulated bone tap apparatus are generally described. In some examples, articulated bone drills and taps may comprise bendable spines, movable bits, and flexible cylindrical tap or drill sleeves. The movable bit may be engaged at a distal end of the spine, and tensioning the spine and/or longitudinal displacement of at least one spine section with respect to at least one other spine section may be effective to steer the bit. The flexible cylindrical sleeve may be adapted to at least partially encase the spine, and the sleeve and the bit may be mechanically engaged so that rotation of the sleeve around the spine is effective to rotate the bit.
US09597088B2 Medical implant and manufacturing method thereof
A medical implantable occlusion device (100) is disclosed comprising a braiding of at least one thread, an expanded diameter portion (102), and a tubular member (103) having a distal endpoint closest to the expanded diameter portion having a distal rim (107). The braiding comprises a stem (108) having a first end connected to the expanded diameter portion and a second end connected to the distal region, where the stem in a relaxed state is partly sunk into the tubular member beneath the distal rim (107), wherein the proximal region comprises a connecting member (113), wherein ends of the at least one thread are fixed to the connecting member, the expanded diameter portion comprises returning loops of the at least one thread whereby opposite ends of the at least one thread forming the expanded diameter portion are fixed to the connecting member.
US09597087B2 Filamentary devices for treatment of vascular defects
Devices and methods for treatment of a patient's vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments may include a permeable shell configured to occlude blood flow therethrough.
US09597083B2 Circular stapling instrument
A circular stapling instrument including a stapling forming assembly that is actuated independently from actuation of the cutting assembly is provided. The instrument includes a handle assembly, an elongate body extending from the handle assembly, a cartridge assembly mounted on a distal end of the elongate body. The cartridge assembly includes a pusher assembly and a knife assembly. The knife assembly is selectively fixed relative to the pusher assembly.
US09597078B2 Surgical stapling device with dissecting tip
A dissecting tip is provided for use with a surgical stapler or instrument. In one embodiment, the dissecting tip is secured to the end effector of a surgical stapler, e.g., to the anvil assembly or cartridge assembly. The dissecting tip extends distally from the end effector and is configured to dissect or separate target tissue from certain tissue, e.g., adherent, connective, joined or other tissue.
US09597076B2 Surgical instrument with double cartridge and anvil assemblies
An end effector for use with a surgical instrument having a first cartridge assembly configured to deploy a first set of fasteners and a second cartridge assembly disposed distally of the first cartridge assembly. The second cartridge assembly is configured to move between an open position and an approximated position relative to clamp tissue. A central rod extends between the first cartridge assembly and the second cartridge assembly.
US09597073B2 Apparatus for forming variable height surgical fasteners
A surgical device for applying a plurality of surgical staples is provided. The device includes a staple fastening assembly attached to a surgical instrument. The staple fastening assembly includes a pair of cooperating jaws, a jaw operating mechanism, and a gap sensor. A staple magazine having a plurality of staples and an anvil member having a plurality of staple pockets are attached to the jaws. The staple magazine includes a staple crimping cam and a staple dimpling cam that are operatively coupled to the surgical instrument. The jaw operating mechanism is operatively connected to a drive assembly in the surgical instrument for moving the jaws for automatically setting a tissue gap between the cooperating jaws. The gap sensor cooperates with the jaw operating mechanism for controlling staple formation.
US09597070B2 Method of fastening soft tissue to bone with a stacked plate suture anchor
A surgical anchor comprises a plurality of plates configured into a stack with successive plates within the stack being vertically arrayed with respect to the stack. The stack has an undeployed configuration, and a deployed configuration. In the deployed configuration one or more of the plates is positioned outwardly more laterally with respect to the stack than in the undeployed configuration so as to retain the anchor in a bone hole. A biasing member between the plates in the stack biases the one or more plates toward the deployed configuration. The biasing member can provide a torsional force to induce the plates to rotate and fan outwardly.
US09597068B2 Self-cinching suture anchors, systems, and methods
Various self-cinching suture anchors, self-cinching suture anchor systems, and methods of use are provided. In one exemplary embodiment, a suture anchor is provided that includes an outer member and an inner member configured to be received within the outer member. The inner and outer members can define a gap that allows a suture to be movably disposed within the outer member, e.g., within the gap, when the inner member is disposed within the outer member. The inner member can be configured to be secured within the outer member by a knot of the suture having a diameter greater than a width of the gap so as to fix the inner member within the outer member, while still allowing uni-directional tensioning of the suture.
US09597067B2 Packaged antimicrobial medical device and method of preparing same
A method of making a packaged antimicrobial suture. The method includes the steps of providing a containment compartment molded from a polymeric resin comprising a polymeric material and an antimicrobial agent, positioning a suture within the containment compartment, the suture comprising one or more surfaces; covering the containment compartment having the suture in an outer package cover having an inner surface, and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the containment compartment to the suture, while retaining an effective amount of the antimicrobial agent on the containment compartment, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment. A packaged antimicrobial suture is also provided.
US09597063B2 Expandable introducer sheath to preserve guidewire access
An introducer sheath is described. The introducer sheath may include a tubular body. The tubular body may extend from a distal end toward a proximal end. The tubular body may include a lumen. The lumen may at least partially be defined by a wall. A channel may be disposed within the wall. The channel may be configured to receive a guidewire. The tubular body may include an expandable portion expandable to increase a cross-sectional area of the lumen.
US09597059B2 Correcting for unintended motion for ultrasonic eye scans
A device and method are disclosed for detecting and correcting unintended eye movements that may occur during an ultrasound scan by monitoring multiple position tracking sensors, examples being but not limited to ultrasound or optical position sensors. These position tracking sensors are in addition to the ultrasound imaging transducer and are in a fixed position on the scan head so as not to move during the scanning operation. These position tracking sensors can continuously monitor the distance to the cornea or other clearly defined anatomical features of the eye such as the posterior pigment layer of the iris during the movement of the scan head assembly and can provide continuous multi-dimensional correction for any unwanted motion of the eye relative to the scan head that may occur during the ultrasound scan.
US09597049B2 Image display control device, operating method for same, and image display control program
The image display control device includes a thumbnail image display control unit that displays a thumbnail image of a tomographic image forming a three-dimensional image, a display instruction receiving unit that receives an instruction to display the three-dimensional image, and a tomographic image display control unit that displays a plurality of tomographic images on a display screen which is different from a display screen on which the thumbnail image is displayed such that the tomographic images are sequentially switchable when the instruction to display the three-dimensional image is received. The thumbnail image display control unit newly generates a thumbnail image of the tomographic image displayed immediately before the display of the tomographic image ends, changes the current thumbnail image to the new thumbnail image, and displays the new thumbnail image.
US09597044B2 Extremity imaging apparatus for cone beam computed tomography
An apparatus for cone beam computed tomography of an extremity has a digital radiation detector and a first device to move the detector along a circular detector path extending so that the detector moves both at least partially around a first extremity of the patient and between the first extremity and a second, adjacent extremity. The detector path has radius R1 sufficient to position the extremity approximately centered in the detector path. There is a radiation source with a second device to move the source along a concentric circular source path having a radius R2 greater than radius R1, radius R2 sufficiently long to allow adequate radiation exposure of the first extremity for an image capture by the detector. A first circumferential gap in the source path allows the second extremity to be positioned in the first circumferential gap during image capture.
US09597042B2 Perfusion imaging
A method is disclosed that includes decomposing, with a decomposer, agent-based time series projection data for an object or a subject into at least an agent based component. A projection data decomposer includes a time series decomposer that determines agent-based projection data based on agent-based time series projection data based on at least two energy dependent components. A computer readable storage medium containing instructions which, when executed by a computer, cause the computer to perform the act of determining an agent-based component of agent-based time series projection data utilizing at least two components of the agent-based time series projection is provided.
US09597040B2 Field limiting device synchronized with scan motion
According to one embodiment, the x-ray apparatus includes an x-ray source adapted to emit an x-ray beam and a detector adapted to receive the x-ray beam of the x-ray source. The x-ray source is adapted to be moved in relation to a first portion of the x-ray apparatus and the detector is adapted to be moved in relation to a first portion of the x-ray apparatus. A control unit controls the movement of the x-ray source and detector. The x-ray source and the detector are adapted to rotate in relation to a first portion of the x-ray apparatus. Further, the x-ray beam is directed essentially towards the detector during the movement of the x-ray source and the detector.
US09597037B2 Systems, methods, and computer-readable media for determining when a subject is likely to be affected by a genetic disorder
Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information.
US09597028B2 Biological fluid collection device and biological fluid separation and testing system
A biological fluid collection device that is adapted to receive a multi-component blood sample having a cellular portion and a plasma portion is disclosed. After collecting the blood sample, the biological fluid collection device is able to separate the plasma portion from the cellular portion. After separation, the biological fluid collection device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The biological fluid collection device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with an anticoagulant. The biological fluid collection device is engageable with a testing device for closed transfer of a portion of the plasma portion from the biological fluid collection device to the testing device. The testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results.
US09597025B2 Biological signal measuring system and biological signal measuring apparatus
A biological signal measuring system includes: a light emitter emitting light beams having different N kinds of wavelengths, where N is an integer of four or more; a light receiver outputting N kinds of signals respectively in accordance with received light intensities of the N kinds of light beams that have been passed through or reflected from a living tissue; a first calculating section acquiring N kinds of light attenuations based on the N kinds of signals; a second calculating section acquiring (N−1) kinds of blood-derived light attenuations based on two light attenuations related to (N−1) kinds of combinations selected from the N kinds of light attenuations; a third calculating section identifying concentrations of (N−1) kinds of in-blood substances based on the (N−1) kinds of blood-derived light attenuations; and an outputting section outputting the identified concentrations.
US09597023B2 Oximetry assembly
Systems, methods, and devices for intercommunication between a medical sensor and an electronic patient monitor are provided. For example, one embodiment of a system for communicably coupling a medical sensor to an electronic patient monitor may include a sensor-side communication connector and a monitor-side communication connector. The sensor-side communication connector may be capable of receiving a raw physiological measurement signal from the medical sensor, and the monitor-side communication connector may be capable of providing a digital physiological measurement signal based at least in part on the raw physiological measurement signal to the electronic patient monitor via a data link.
US09597020B2 Measuring device and glucose concentration measurement method of the measuring device
The inventive concept relates to a measuring device. The measuring device irradiates a first beam including a polarization component and a second beam which is a wavelength swept laser having a coherence length previously set and can measure a glucose concentration of an aqueous humor by measuring an optical path length and the rotation amount of a polarization plane respectively from a first output beam and a second output beam being output from an eye.
US09597019B2 Method of ensuring date and time on a test meter is accurate
A method of operating a glucose test meter is provided. The method can be achieved by storing a plurality of glucose readings to a first memory of the test meter, each of the glucose readings having a time stamp and an order index, the time stamp comprising a date and a time when the glucose reading was performed, the order index indicating an order in which the plurality of glucose readings was saved to the first memory; determining whether successively saved glucose readings have time stamps in chronological order consistent with the order index; and indicating that the date and the time setting in the test meter is incorrect if there are successively saved glucose readings having time stamps inconsistent with the order index.
US09597015B2 Joint angle tracking with inertial sensors
A method for estimating joint angles of a multi-segment limb from inertial sensor data accurately estimates and tracks the orientations of multiple segments of the limb as a function of time using data from a single inertial measurement unit worn at the distal end of the limb. Estimated joint angles are computed from measured inertial data as a function of time in a single step using a nonlinear state space estimator. The estimator preferably includes a tracking filter such as an unscented Kalman filter or particle filter. The nonlinear state space estimator incorporates state space evolution equations based on a kinematic model of the multi-segment limb.
US09597013B2 Method and apparatus for detecting ineffective inspiratory efforts and improving patient-ventilator interaction
A method and system for detecting an ineffective effort of a patient being mechanically ventilated by a ventilator comprises (i) monitoring a respiratory flow of air of the patient after said ventilator has cycled; (ii) creating a signal indicative of said flow; (iii) removing artifact from said signal; (iv) monitoring said signal for perturbations; and (v) determining that an ineffective effort has occurred when said perturbation is significant.
US09597008B2 Imaging probe and method of obtaining position and/or orientation information
A method of obtaining information about the position and/or orientation of a magnetic component relatively to a magnetometric detector, the magnetic component and the magnetometric detector being moveable independently from each other relatively to a static secondary magnetic field, the method comprising the steps of: measuring in the presence of the combination of both the magnetic field of the magnetic component and the static secondary magnetic field essentially simultaneously the strength and/or orientation of a magnetic field at at least a first position and a second position spatially associated with the magnetometric detector, the second position being distanced from the first position; and combining the results of the measurements to computationally eliminate the effect of the secondary magnetic field and derive the information about the position and/or orientation of the magnetic component.
US09597001B2 Separating clinically relevant sources of electrical activity in ECG signals
This invention provides a fully automatic method and a system for detecting and classifying cardiac arrhythmias from a surface ECG record. The method defines four relevant parameters whose values are extracted from said ECG record. Clinically relevant conclusions are assigned to various combinations of the obtained values of said parameters. The method can be employed for detecting fetal QRS complexes from abdomen ECG of a pregnant woman.
US09597000B2 Nerve interface electrode with fibers for insertion between nerve fascicles
A nerve interface electrode has a plurality of conductive fibers. The fibers have a nonconductive sheath (108) surrounding a conducting wire. A conducting region (105) of the wire is exposed to the interior of the nerve (200). The fibers are configured for insertion between fascicles (204) of the nerve. In other teachings, a layer of polymer material configured to switch from a high strength/tensile modulus state to a low strength/tensile modulus state upon introduction of the fibers into the nerve is disposed on the fibers.
US09596998B2 Ballistocardiographic sensor system with a sensor arrangement and method of ballistocardiographic detection of body movements
Sensor arrangement, comprising at least one ballistocardiographic sensor for detecting body movements of a subject and at least one noise sensor for detecting vibration, method of ballistocardiographic detection of body movements, ballistocardiographic sensor system and uses of the sensor arrangement. It is suggested to pickup an external noise signal using an inertia sensor that is vibration isolated from a subject under ballistocardiographic examination.
US09596992B2 Intelligent nursing care device
The present disclosure discloses an intelligent nursing care device, which is a wearable nursing care device and comprises a monitoring unit that acquires a position information and a health condition information of a wearer in real time, and a control unit that determines, based on the position information and the health information acquired by the monitoring unit, a safety condition and a health condition of the wearer, and transmits a determination result to at least one of a cloud server and a monitoring terminal. By wearing the intelligent nursing care device, an intelligent nursing care service and safety tracking service are provided to a wearer.
US09596988B2 Pressure sensors for small-scale applications and related methods
Certain pressure sensor devices are much smaller than prior art devices, yet are at least as sensitive as the prior art devices. A capacitive pressure sensor can include a flexible substrate that permits bending of a pressure sensing region without significantly affecting operation thereof. The pressure sensor can include a flexible membrane in which an electrode is sandwiched between two layers of polymeric material. The sandwiched electrode can be extremely close to a reference electrode so as to provide for highly sensitive capacitance readings, yet the membrane can be restricted from contacting the reference electrode under high pressure conditions.
US09596983B2 Methods and systems for tracking a torsional orientation and position of an eye
Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye with a second image of an eye. In another embodiment, the present invention provides methods and software for tracking a torsional movement of the eye. In a particular usage, the present invention tracks the torsional cyclorotation and translational movement of a patient's eye so as to improve the delivery of a laser energy to the patient's cornea.
US09596982B2 Endoscope system and composite image generation method
A blue signal B, a green signal G, and a red signal R are obtained by imagining a subject illuminated with white light W using a color CCD 44. Based on these signals B, G, and R, a normal light image in which a wavelength component of a visible light region is included is generated. Based on the signals B, G, and R, a brightness signal I ((B+G+R)/3) showing the average brightness of the subject is generated. A pixel region exceeding the fixed threshold value Th1 of the brightness signal I is extracted as a superficial microstructure P, such as a pit pattern. A microstructure enhancement image 72 is generated by combining the normal light image with a superficial microstructure image 70 obtained by extracting the superficial microstructure P. The generated microstructure and blood vessel enhancement image 72 is displayed on a monitor 14.
US09596969B2 Vacuum cleaning device, comprising a unit with a movable surface for generating an oscillating airflow
A vacuum cleaning device comprises a unit (1) for aerodynamically affecting dust particles and/or a surface (40) to be cleaned in order for the particles to become dislodged from the surface (40) and to be received by the unit (1). The unit (1) comprises a housing (10) having an internal space (11) enclosed by a housing wall (12) in which at least one opening (13) is arranged, a movable surface (30) which is integrated in the housing wall (12), and means (31) for actuating the movable surface (30), which are adapted to realize an oscillating movement of the surface (30) that causes air to alternately be drawn into the housing (10) through the opening (13) and expelled from the housing (10) through the opening (13). At least a portion of the housing wall (12), particularly a portion of the housing wall (12) in which the opening (13) is located, is movably arranged in the unit (1).
US09596968B2 Floor care appliance
A brush vacuum cleaner having a brush set facing the floor with a driven brush roller, wherein the brush set can be connected via a pivotable connecting element in the form of a connecting piece for a filter housing attachable to a handle having a hand grip. The brush set accommodates an electric motor for a suction fan and for the drive of the brush roller. An electrical switch is provided for switching the electric motor on and off which is disposed on the side wall as a lateral flank of the brush set in the form of a foot operated switch. The switch with its external control surface projects outwards with respect to the side wall in the switched-off position whereas in the switched-on position the control surface ends with neighboring or adjacent surface sections of the side wall without overhang.
US09596967B2 Cleaner and cleaner accessory
A cleaner including a body configured to generate a suction force, a suction head configured to suction air and dirt while making contact with a cleaning surface, a handle pipe configured for manipulation by a user, a flexible hose connecting the handle pipe to the body, an extension pipe connecting the suction head to the handle pipe, and an accessory assembly coupled to the handle pipe to perform a cleaning in place of the suction head, the accessory assembly comprising an accessory body, a Dusting tool on which a brush is mounted, a Crevice tool to clean a gap, and an Upholstery tool to clean fabrics, the Upholstery tool being rotatably coupled to the accessory body, thereby enhancing the convenience of use and cleaning efficiency.
US09596966B1 Telescopic urinal holder
The container retention assembly for retaining a urinal at a selected height includes a base that may be positioned on a support surface. The base includes a bottom rod and a top armature that extend upwardly to support a portable urinal. The assembly is adapted to be rolled like a walker or parked adjacent a bed in order for the portable urinal to be supported when not in use.
US09596965B2 Potty with liquid management system
A potty for use by young children includes a waste collector and a seat adapted to rest on the waste collector. The potty can be placed in an aperture formed in a base.
US09596962B2 Infant towel drying mat
An infant towel drying mat that is intended to provide a convenient and effective apparatus to aid in the drying of a human infant or a pet animal. A drying mat has a first section, a second section, and a section hinge, wherein the first section and the second hinge are adjacently connected to the section hinge; the section hinge being positioned in between the first section and the second section and allows for multiple configurations of the infant towel drying mat. A plurality of connection tabs is adjacently connected to the drying mat and perimetrically positioned around the drying mat. Each of the plurality of connection tabs includes a protrusion connected to the drying mat, a surface fastener to be secured to a surface, and a press towel holder for mounting a towel. The surface fastener and the press towel holder are positioned opposite each other about the protrusion.
US09596961B2 Use of rigid polyurethane foam to encapsulate plumbing in a therapy bath
A wall structure for a composite tub includes a surface side for facing an interior of the tub, a polyurethane layer backing and attaching to the surface side, plumbing backing the polyurethane layer, and an encapsulation layer encapsulating the plumbing and backing and attaching to the polyurethane layer so that damage to the plumbing is minimized.
US09596957B2 Relief and safety valve for instant beverage machines
A hydraulic circuit for instant beverage machines includes a tank, a water extraction pipe contained in the tank, a flow-meter connected to the extraction pipe, a pump, a first vibration-damping valve, a boiler, a second relief and safety valve, a water/steam faucet, a third beverage flow valve, and a recovery tank.
US09596956B2 Apparatus for and method of making coffee
An apparatus for making coffee, in accordance with an automated pour-over method, includes a housing having a movable water spout, a basket for holding a bed of coffee grounds below the spout, a pump for moving water through the spout for delivery and distribution onto the bed, and a drive for moving the spout along a hypotrochoidal path during distribution of the water to saturate the bed with substantially uniform water coverage and to extract the coffee with substantial consistency as the water permeates and passes by gravity through the bed.
US09596954B2 Cookware that functions as a low pressure cooker
An eco green cookware is provided, having a double-layered wall structure and comprising a heat transfer medium within a cavity of the double-layered wall structure. The eco green cookware comprises: a container comprising an inner shell and an outer shell, wherein upper parts of the inner shell and outer shell are rolled a number of times together to form a rolled joint, an upper part of the inner shell is provided with a concave member, a heat transfer medium is provided within the cavity, a first heat transfer member is inserted and installed at the bottom portion of the cavity, and a second heat transfer member is affixed to the bottom surface of the first heat transfer member; an inner cover comprising an inner peripheral portion in the form of an inverted “L” whose inside bend forms a round portion; an outer cover; and pressure release devices.
US09596952B2 Secured receiving arrangement for a delivered parcel
A secured receiving arrangement for a delivered parcel includes a parcel receptacle for the delivered parcel to be enclosed therein; a lock arrangement to lock and unlock the lid of the parcel receptacle; and a securing device to secure the parcel receptacle to a door at the property to where the delivered parcel is addressed. The securing device is attached at one end to the parcel receptacle and at the other end includes an abutment such that when the securing device is slid under the door and the door is then closed, un-securing the parcel receptacle from the door is prevented by the abutment of the securing device engaging the internal side of the door.
US09596949B1 Necklace support
A rack supports and displays loop-like articles, such as necklaces. The rack includes a bar having a series of circumferential grooves and a holder for supporting the bar from a vertical surface. In one implementation, the holder is at the center of the bar, and is rigidly connected to the bar. In another implementation, the holder is at one end of the bar, with a pivot support at the other end of the bar. The bar is permanently and pivotally fixed to the pivot support, and releasably received in the holder. In the latter implementation, the bar can be lifted or pivoted out of engagement with the holder so that a necklace can be removed from the bar.
US09596946B2 Active mattress encasement
An active mattress may include a top panel, a bottom panel and multiple side panels. One or more of the side panels are zippered together, The un-zippered side panels fixedly connect the top and bottom portions of the side panels. In another embodiment, an inflatable volume is integrated into the bottom panel. Alternatively, the inflatable volume may be integrated with a separate detachable cover and attached to the bottom panel by conventional means. The various configurations of the encasement allows a mattress to be easily rotated, installed, or removed. Optional straps may be provided, fixedly attached to the encasement, to allow the encasement to be snugged against the mattress. This enables the encasement to be used with a relatively wide range of mattress sizes and still provide a snug fit.
US09596944B2 Integration of distributed thermoelectric heating and cooling
A thermoelectric device includes an elongated panel, formed of a thermally insulating material, and having a plurality of thermoelectric elements formed from compacted conductors inside the insulating material and expanded conductors outside the insulating material wherein the thermoelectric elements run substantially parallel to or at an acute angle relative to the long dimension of the panel. The thermoelectric device may be integrated into a variety of surfaces or enclosures needing heating or cooling with controls and configurations to optimize the application.
US09596941B1 Chair back with height and lumbar adjustment
An office chair including a chair back assembly that is independently adjustable to adjust the vertical height of the chair back and to provide lumbar support. The chair back assembly includes a flexible back shell that is movable vertically along a back support yoke. The vertical movement of the flexible back shell adjusts the vertical height of the chair back assembly relative to the seat. The chair back assembly further includes a lumbar adjustment mechanism having an adjustment cable connected to a bottom end of the flexible back shell. Operation of the lumbar adjustment mechanism moves the bottom end of the flexible back shell vertically within a pair of spaced lower movement slots. The movement of the bottom end of the flexible back shell increases the amount that the flexible back shell protrudes from the back support yoke, thereby increasing the lumbar support.