Document Document Title
US09499855B2 Compositions, methods, and computer systems related to making and administering modified T cells
Embodiments described herein relate to methods, devices, and computer systems thereof for the derivation of T CAR libraries (Universal Subject or Individual Subject) for personalized treatment of disease in a subject. In certain embodiments, differential screening of normal and diseased tissue expression data is utilized to determine disease-specific antigens and thereby generate T CAR cells reactive to such antigens to form a disease-specific library. In certain embodiments, determination of the most effective T CAR clones from the disease-specific library is based on the subject's own disease-specific antigens. In certain embodiments, a subject is treated with a therapeutically effective amount of T CAR clones.
US09499853B2 Biosensing system with extended lifetime via cofactor recycling
The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
US09499848B2 Methods for high fidelity production of long nucleic acid molecules
In a method for generating a long nucleic acid molecule, nucleic acids immobilized on a surface and having overlapping complementary sequences is released into solution. The overlapping complementary sequences are hybridized to form hybridized nucleic acids, followed by extension or ligation of the hybridized nucleic acids to synthesize the long nucleic acid molecule. The nucleic acids may comprise first and second series of nucleic acids having redundant overlapping sequences, wherein nucleic acids from the first and second series are complementary to each other. The complementary nucleic acids are hybridized to form the hybridized nucleic acids. The generated long nucleic acid molecule may have a predetermined sequence element, and it may be introduced into a system wherein the predetermined sequence element is required for replication, such that replication of the synthesized long nucleic acid molecule is indicative of the presence of the predetermined sequence element in the long nucleic acid molecule.
US09499847B2 Production of closed linear DNA using a palindromic sequence
A primer for the amplification of a DNA template comprising a protelomerase target sequence, particularly for production of closed linear DNA, which primer is capable of specifically binding to a palindromic sequence within a protelomerase target sequence and priming amplification in both directions.
US09499845B2 Genetically engineered microorganisms that metabolize xylose
The invention provides methods of cultivating oil-bearing microbes using xylose as a fixed carbon source. Also provided are microorganisms that have been genetically engineered to metabolize xylose as a fixed carbon source allowing them to convert xylose into oils. Particular advantages of the processes provided herein include production of oils rather than alcohols through the microbial fermentation processes utilizing xylose.
US09499843B2 Method of producing oil from a microorganism
The invention relates to a micro-organism comprising a hydrogenase enzyme system which is capable of converting carbon dioxide into formic acid and a second enzyme system which is capable of converting formic acid into aliphatic carboxylic acids having a chain length of five or more carbon atoms. Also described are various methods for producing oil, as well as other aspects of the invention.
US09499840B2 Powered stowable vehicle seat and associated seat frame assembly
A vehicle seat has a seat frame assembly including a seat base frame that may be shifted between a raised position and a lowered position, and a seatback frame pivotally attached to the seat base frame and foldable from a vertical position to a position atop the collapsed base frame. The seat base frame is pivotally connected to the vehicle floor by at least one front pivot leg which is pivotally connected for rotation with respect to both the vehicle floor and the base frame. A motor is mounted in a stationary position on the vehicle floor and connected to provide a relative torque between the seat base frame and one of the at least one pivot legs for powered movement of the seat base frame to and from the use position and the stow position.
US09499838B2 Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
The present invention relates to a human artificial chromosome which is genetically transmissible to the next generation with high efficiency and the method for using the same. More specifically, the present invention relates to: a human artificial chromosome in which an about 3.5 Mb to about 1 Mb region containing an antibody λ light chain gene derived from human chromosome 22 is bound to a chromosome fragment which is transmissible to a progeny through a germ line of a non-human animal, said chromosome fragment is derived from another human chromosome; a non-human animal carrying the human artificial chromosome and an offspring thereof; a method for producing the non-human animal; a method for producing a human antibody using the nonhuman animal or an offspring thereof; and a human antibody-producing mouse carrying the human artificial chromosome.
US09499834B2 Rice cultivar designated ‘CL151’
A novel rice cultivar, designated ‘CL151,’ is disclosed. The invention relates to the seeds of rice cultivar ‘CL151,’ to the plants of rice ‘CL151,’ and to methods for producing a rice plant produced by crossing the cultivar ‘CL151’ with itself or another rice variety, and to single gene conversions of such plants. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar ‘CL151’ with another rice cultivar. The invention further relates to other derivatives of the cultivar ‘CL151.’
US09499833B2 Wheat plants having increased resistance to imidazolinone herbicides
The present invention is directed to wheat plants having increased resistance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants containing one or more IMI nucleic acids such as a Gunner IMI 205, Gunner IMI 208 and Madsen IMI cultivar. The present invention also includes seeds produced by these wheat plants and methods of controlling weeds in the vicinity of these wheat plants.
US09499831B2 Plant transcription factors, promoters and uses thereof
Polynucleotide molecules encoding transcription factors, promoter elements, binding partners and methods of use in increasing drought tolerance, yield, and abiotic stress tolerance are disclosed. ERF transcription factors and Cor410b promoter sequences are disclosed.
US09499818B2 Methods and means for efficient skipping of at least one of the exons 51-53, 55, 57 and 59 of the human duchenne muscular dystrophy gene
The invention relates to a method where a molecule is used for inducing and/or promoting the skipping of at least one of the exons 51-53, 55, 57 and 59 of the DMD pre-mRNA in a patient, preferably in an isolated cell of a patient. The method comprising providing the cell and/or the patient with a molecule. The invention also relates to the molecule and its composition that is being used for inducing exon skipping.
US09499816B2 Methods of novel therapeutic candidate identification through gene expression analysis in vascular related diseases
The present invention discloses multiple treatment regimens for vascular-related diseases and disorders. The present invention provides for methods of treating vascular-related disorders based on gene expression studies from samples collected from individuals having symptoms of vascular-related disorders. Additionally, methods are disclosed involving diagnostic techniques to focus treatment regimens. Finally, methods of treating vascular-related disorder involving targeting microRNAs are also disclosed.
US09499812B2 Nucleic acid sample preparation
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
US09499811B2 Ligation enhancement
Compositions and methods are provided for enhancing enzymatic ligation between nucleic acid fragments that relies on one or more small molecule enhancers having a size of less than 1000 daltons. For example, enhancement of ligation efficiencies are observed for double-stranded nucleic acid fragments that are blunt-ended, have a single nucleotide overhang at the ligation end, or have staggered ends compared to ligation under similar conditions in the absence of the one or more small molecule ligation enhancer. The use of small molecule enhancers for ligating nucleic acids results in an increased number of transformed host cells after transformation with the ligated molecules. This enhancement can be observed with chemically transformed host cells and with host cells transformed by electroporation.
US09499805B2 Methods and compositions for synthetic RNA endonucleases
The present invention provides sequence specific restriction enzymes for site-specific cleavage of RNA, as well as methods of their use.
US09499803B2 Variant LovD polypeptide
The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the disclosure teaches that variants of the LovD acyltransferase polypeptide can be engineered to exhibit properties that facilitate their use in the production of simvastatin and/or huvastatin. The materials and processes disclosed herein are designed so that fermentation facilities currently producing lovastatin can be converted to producing simvastatin and related compounds with minimal modifications.
US09499797B2 Method of making induced pluripotent stem cells
A method of producing an induced pluripotent stem cell includes introducing into a somatic cell one or more non-viral expression vectors. The vectors include one or more of an Oct family gene, a Klf family gene, a Sox family gene, a Myc family gene, a Lin family gene, and Nanog gene. The somatic cell is then cultured in a medium that supports pluripotent stem cells. At least a portion of the one or more introduced non-viral expression vectors is not substantially integrated in the chromosome.
US09499790B2 Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
The present invention relates to a composition for promoting differentiation of pluripotent stem cells into cardiac muscle cells, and a method for inducing differentiation of pluripotent stem cells into cardiac muscle cells and a method for preparing cardiac muscle cells.
US09499787B2 Method for differentiating stem cells into neurons
The present invention relates to a method for differentiating stem cells into neurons, and is characterized in that stem cells are treated with a culture additive comprising lipoic acid, albumin, hydrocortisone, and insulin after culturing for differentiation into neurons. Since the neurons produced according to the method for producing neurons of the present invention express nestin, neuroD1, neuron-specific enolase (NSE), neurofilament (NF), tau, microtubule-associated protein 2 (MAP2), and doublecortin (DCX), just as normal mature neurons do, the neurons of the present invention can be effectively used in various therapeutic agents for neurons and as cell origins for an in vitro study system.
US09499784B2 Process for production of microalgae, cyanobacteria and metabolites thereof including lipids and carbohydrates
The present invention relates to processes for the production of microalgae, cyanobacteria and/or metabolites thereof. Described herein is a process involving, the use of a stimulus applied to a microalgal or cyanobacterial culture to enhance the production of one or more metabolites. Also described herein, is a process for the production of microalgae and/or cyanobacteria comprising an adaptation stage wherein an algal/cyanobacterial culture is grown on a process water feedstock and/or under light emitting diodes (LEDs) emitting light within the spectrum of light wavelengths between around 400 nm and 700 nm, and a production phase, wherein the microalgae or cyanobacteria are grown on the same process water feedstock and/or under the same light conditions used in the adaptation stage. The invention also relates to specific microalgal strains.
US09499782B2 Automatic aseptic sampling valve for sampling from enclosed containers
A sample can be collected from an enclosed container by opening a sample collection valve and drawing the sample from the enclosed container. After delivery of the sample out of a fluid flow path, a sanitizing fluid can be directed along the fluid flow path to sanitize the fluid flow path.
US09499781B2 Disposable bioreactor condenser bag and filter heater
Disclosed herein is a system and method for condensing moisture in a moist gas stream entering a bioreactor or leaving a bioreactor, forming a dry gas stream for entering or leaving the bioreactor.
US09499778B2 Automated intracytoplasmic sperm injection assisted fertilization system
An integrated automated system comprising a microfluidic cassette, and methods of use thereof, for intracytoplasmic sperm injection assisted fertilization. The microfluidic cassette and the integrated automated system provides a complete set-up of human gametes for assisted in vitro fertilization, including proper cell stage recognition, gamete propulsion via microfluidic currents, microinjection of a spermatozoon into an oocyte, and subsequent embryo culture and monitoring, thus allowing widespread distribution of in vitro insemination by favoring affordability.
US09499777B2 Process for producing malt-based drink from malt fractioned by tissue
A process for producing malt-based beverage, in which any components, affecting flavor, foam quality, flavor stability and haze stability, of the malt-based beverage can be regulated by separating dried germinated barley as a raw material for malt-based beverage by tissues. In particular, the process for producing malt-based beverage comprises separating dried germinated barley into endosperm, endothelial layer, husk, acrospire, malt rootlets and unseparated part fractions and preparing a starting material of malt-based beverage from each or blend of the thus obtained by-tissue fractions, the each or blend optionally further mixed with wholegrain malt not subjected to fractioning, so that any components, affecting flavor, foam quality, flavor stability and haze stability, of the malt-based beverage can be regulated.
US09499769B2 Process for preparing polyurea microcapsules
The present invention relates to a process for producing microcapsules with a polyurea wall, as well as to the microcapsules themselves and consumer products comprising these microcapsules. The process of the invention uses 3,5-diamino-1,2,4-triazole as a specific polyamine for forming the wall with the polyisocyanate.
US09499766B2 Nanoparticle compositions and methods for making and using the same
A composition that includes solid lubricant nanoparticles and an organic medium is disclosed. Also disclosed are nanoparticles that include layered materials. A method of producing a nanoparticle by milling layered materials is provided. Also disclosed is a method of making a lubricant, the method including milling layered materials to form nanoparticles and incorporating the nanoparticles into a base to form a lubricant.
US09499765B2 Lubricating oil compositions for construction machines
The present invention is directed to a Zinc-free transmission oil composition for construction machinery comprising: (i) a major amount of an oil of lubricating viscosity, (ii) at least 0.25 wt. % of a dithiophosphorylated carboxylic acid compound, and (iii) a succinimide dispersant derived from a polyisobutylene group of 1200 molecular weight or less. Also provided is a method for lubricating the transmission of a construction machine comprising lubricating the transmission with a Zinc-free transmission oil composition comprising: (i) a major amount of an oil of lubricating viscosity, (ii) at least 0.25 wt. % of a dithiophosphorylated carboxylic acid compound, and a succinimide dispersant derived from a polyisobutylene group of 1200 molecular weight or less.
US09499763B2 Additive compositions with plural friction modifiers
A lubricating oil comprising a major amount of base oil and a minor amount of an additive package, wherein the additive package comprises:(A) a friction modifier component selected from: (a) one or more a reaction products of an alcohol with a compound of the formula IV: and (b) one or more compounds of the Formulae II-III: wherein R is a linear or branched, saturated, unsaturated, or partially saturated hydrocarbyl having about 8 to about 22 carbon atoms, R2 and R3 are independently selected from hydrogen C1-C18 hydrocarbyl groups, and C1-C18 hydrocarbyl groups containing one or more heteroatoms; X is an alkali metal, alkaline earth metal or ammonium cation and n is the valence of cation X, and reaction products of amines, amino alcohols, alkali or alkaline earth metal hydroxides, alkali or alkaline earth metal oxides and mixtures thereof with compounds of the Formula IV: Where R is as defined above; and (B) at least one friction modifier that is different from the one or more compounds (A).
US09499759B2 Paper-based wet friction material of automotive auto transmission
A multilayer paper-based wet friction material of an automotive auto transmission may improve noise and vibration characteristics, heat resistance, wear resistance, compression resistance, and oil absorbency. The paper-based wet friction material of an automotive auto transmission includes: a first layer using cellulose pulp as a matrix and including a first functional additive; a second layer stacked on the first layer, using the cellulose pulp as the matrix, and including the second functional additive; and a hydrogen bonding layer mediating between the first layer and the second layer. The cellulose pulp of the first and second layers is cotton linter.
US09499758B2 Fuel compositions
Low sulphur marine fuel compositions are provided. Embodiments comprise greater than 50 to 90 wt % of a residual hydrocarbon component, with the remaining 10 and up to 50 wt % selected from a non-hydroprocessed hydrocarbon component, a hydroprocessed hydrocarbon component, and a combination thereof. Embodiments of the marine fuel composition can have a sulphur content of about 0.1 wt % or less.
US09499757B2 Method and machine for the production of a low emission biomass fuel composition from waste materials
The present disclosure provides a novel method and machine for the production of a biomass composition from waste materials including the steps of evaluating the waste material for emissions related factors, treating the evaluated waste material with the additive composition to form a low emissions biomass composition and shaping the biomass composition into solid fuel formations. The present invention further provides an additive composition used in the treatment of the waste materials that comprises an emission sponge, a filler and optional BTU modifier. The treating step includes the steps of sizing selected waste materials, blending the sized waste materials with the additive composition formulated specifically for the waste material and forming with a press the blended waste materials into solid fuel formations. The resulting biomass solid fuel formations produce lower emissions than typically produced by coal and may be combined with, or used in place of coal in fuel burning structures and devices.
US09499754B2 Methods for converting motor oil into fuel
Methods for converting motor oil into fuel generally include forming a conversion mixture of an alcohol and a base, and adding the conversion mixture to motor oil, to form a reaction mixture. The methods can also include adding a high nitrate compound and an amino acid to the reaction mixture and ozonizing the reaction mixture. The result of the methods can include a three phase system in which the bottom phase is asphalt oil, the middle phase is diesel fuel or jet fuel, and the top phase is sulfuric acid. The three phases can be separated to obtain the final diesel fuel or jet fuel product.
US09499750B2 Process for improving cold flow properties and increasing yield of middle distillate feedstock through liquid full hydrotreating and dewaxing
Novel liquid-full process for improving cold flow properties and increasing yield of middle distillate fuel feedstock by hydrotreating and dewaxing the feedstock in liquid-full reactors.
US09499749B2 Removing unstable sulfur compounds from crude oil
A crude oil which contains at least 0.1 wt % unstable sulfur compounds is treated in a reaction zone at low temperature to convert at least 50 wt % of the unstable sulfur compounds contained therein. The reaction and removal of sulfur from the crude may be facilitated by contacting the crude oil with a catalytic material in the presence of a stripping fluid.
US09499748B2 Petroleum crude oil desalting process and unit
An improved method and process unit for desalting petroleum crude oils in which a portion of the stable emulsion layer which forms in the desalter vessel is withdrawn from the desalter and diluted with a liquid diluent, typically oil or water or both to destabilize the emulsion which is then separated into separate oil and water phases.
US09499747B2 Method and reactor for cracking hydrocarbon
A method for cracking hydrocarbon, comprises: providing steam and hydrocarbon; and feeding steam and hydrocarbon into a reactor accessible to hydrocarbon and comprising a perovskite material of formula AaBbCcDdO3-δ, wherein 0
US09499746B2 Alignment and flattening material compositions, display device comprising same and process for adjusting display color
An alignment material composition, a flattening material composition, a liquid crystal display device and a process for adjusting the display color of the liquid crystal display device. The alignment material composition or the flattening material composition each includes 0.5-20 wt % of an organic additive, which is one or more of spiropyran compounds, Schiff base compounds, and heterocyclic diarylethene compounds. By way of adding the aforesaid organic additive in the orientation layer or the flat layer of the liquid crystal display device, the display color is allowed to be adjusted in a broad color range without affecting other display performances of the liquid crystal display device.
US09499745B2 Liquid crystal composition and liquid crystal display device
A liquid crystal composition contains a specific compound having large dielectric anisotropy as a first component and a specific bicyclic compound having small viscosity as a second component, and may contain a specific compound having high maximum temperature or large dielectric anisotropy as a third component and a specific compound having high maximum temperature or small viscosity as a fourth component, and has a nematic phase. The liquid crystal display device includes the composition.
US09499742B2 Method for enhancing strength and durability of weak soils
The method for enhancing strength and durability of weak soils includes the steps of selecting a weak soil, such as marl or dune sand, mixing the weak soil with 2% cement by weight and between 5% and 30% by weight of Electric Arc Furnace Dust (EAFD) to form a dry mixture, mixing the dry mixture with water to form a substantially homogenized mixture, and curing the homogenized mixture, wherein curing can include the step of sealing the homogenized mixture in an environment having a temperature between 19° C. and 25° C., inclusive, for seven days.
US09499739B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body
Disclosed is a production method of a thermoplastic resin composition comprising: blending a thermoplastic resin (A) and a metal complex (B) and a ligand (C2), wherein the metal complex (B) has a ligand (C1) coordinated therein, and wherein the ligand (C2) has a higher boiling point than the ligand (C1) under atmospheric pressure, and then heating and mixing the resulting blend at a temperature of not less than a boiling point of the ligand (C1) and not more than a boiling point of the ligand (C2), to produce a thermoplastic resin composition that can provide a light-emitting body at low cost in which a light-emitting material is dispersed in the resin in a good dispersion state, excellent in transparency and excellent in light-emitting properties of visible light; a molding material obtained by molding the thermoplastic resin composition; and a light-emitting body obtained by molding the thermoplastic resin composition.
US09499738B2 Solid organic scintillator doped by one or more chemical elements
The invention relates to a solid organic scintillator comprising a polymeric matrix in which there are dispersed one or more fluorophore compounds and one or more chemical elements having an atomic number ranging from 40 to 83, characterized in that said scintillator has a weight content of said chemical elements of at least 5% by weight relative to the total weight of the scintillator, and in that the scintillator emits an emission spectrum comprising an emission peak at a wavelength of at least 550 nm.
US09499735B2 Consolidating composition for treatment of a subterranean formation
Various embodiments disclosed relate to compositions for treating a subterranean formation and methods of using same, such as for consolidation. In various embodiments, the present invention provides a method of treating a subterranean formation, the method including obtaining or providing a composition. The composition includes an aryl component including at least one of an aryldicarboxylic acid, an ester thereof, a salt thereof, and an acid halide thereof. The composition includes an amine or epoxide component that includes at least one of component A and component B. Component A is a linear diepoxide, a poly(alkylamine), or a combination thereof. Component B is an alkoxy- or hydroxy-substituted silane including an epoxy group, an alkoxy- or hydroxy-substituted silane including an amine group, or a combination thereof. The method also includes placing the composition in a subterranean formation.
US09499727B2 Curable compositions containing isocyanate functional components having improved durability
A composition comprising: a) one or more isocyanate functional prepolymers; b) one or more amorphous linear polymers having sufficient polarity to form a homogeneous mixture with the one or more isocyanate functional prepolymers and having a hydroxyl number of about 10 or less; c) one or more forms of carbon black; and d) one or more catalysts for the reaction of isocyanate moieties with active hydrogen atom containing groups.
US09499721B2 Colloidal silica chemical-mechanical polishing composition
A chemical-mechanical polishing composition includes colloidal silica abrasive particles dispersed in a liquid carrier. The colloidal silica abrasive particles include a nitrogen-containing or phosphorus-containing compound incorporated therein such that the particles have a positive charge. The composition may be used to polish a substrate including a silicon oxygen material such as TEOS.
US09499714B2 Controlled crosslinking of latex polymers with polyfunctional amines
The latex polymer compositions of the present invention exhibit latent crosslinking properties. Latent crosslinking in the polymers takes advantage of the fast interaction between the anionic latex charge and the cationic charge associated with polyfunctional amine crosslinkers. Once the latex is coated onto a substrate, the volatile base evaporates and the groups react to form a crosslinked coating with improved wash-off properties.
US09499704B2 Ink, ink cartridge, and ink jet recording method
An aqueous ink for ink jet contains a urethane resin. The urethane resin has a unit derived from a polyether polyol and a unit containing an acidic group. The acid value of the urethane resin is 40 to 140 mg KOH/g. The molar ratio of urethane bonds/urea bonds is 80.0/20.0 or more. Some of the acidic groups in the urethane resin are neutralized with particular neutralizing agents.
US09499699B1 High durability solar absorptive coating and methods for making same
The present invention relates to solar absorptive coatings including a ceramic material. In particular, the coatings of the invention are laser-treated to further enhance the solar absorptivity of the material. Methods of making and using such materials are also described.
US09499698B2 Metal hardmask composition and processes for forming fine patterns on semiconductor substrates
The present invention relates to a novel composition with improved stability containing soluble, multi-ligand-substituted metal compound, a polyol compound and a solvent useful for filling material on photoresist patterns with good trench or via filling properties of microlithographic features, where the filled patterns having good plasma etch resistance in oxygen based plasmas and are used as a hard mask in forming fine patterns on semiconductor substrates by pattern transfer of this hard mask. The present invention further relates to using the novel composition in methods for manufacturing electronic devices.
US09499697B2 Coating composition and a reflective coating system including same
A coating composition is substantially free from chromate and comprises a resin, a metal salt, and an interference pigment. The interference pigment includes mica which has a solar reflective coating disposed thereon. A reflective coating system comprises a cured film formed from the coating composition disposed on a substrate. The cured film has a transparency of at least 75%, as measured according to ASTM 1746. In addition, the cured film has a solar reflectivity of at least 55%, as measured according to ASTM E 1918 and ASTM E 903. The cured film has excellent corrosion resistance properties and adhesion to the substrate.
US09499695B2 Polycarbonate resin composition
The present invention provides a polycarbonate resin composition for molding a molded article having a thin-walled section and exhibiting a high level of flame resistance and impact resistance, and an excellent surface appearance (low-gloss property). More specifically, the present invention is a polycarbonate resin composition for molding a polycarbonate resin molded article having a thin-walled section with a wall thickness of 0.6 mm or less, the polycarbonate resin composition being characterized in that the resin composition contains an oligomeric phosphoric acid ester flame retardant (B1) and/or a phosphazene flame retardant (B2), and the content of flame retardant with respect to 100 parts by mass of polycarbonate resin (A) is: i) 5 to 20 parts by mass when the resin composition contains only the oligomeric phosphoric acid ester flame retardant (B1); ii) 10 to 30 parts by mass when the resin composition contains only the phosphazene flame retardant (B2); or iii) a total of 5 to 30 parts by mass when the resin composition contains both the oligomeric phosphoric acid ester flame retardant (B1) and the phosphazene flame retardant (B2), with the content ratio thereof being 1 to 49 mass % of (B1) and 99 to 51 mass % of (B2), the resin composition additionally contains 3 to 15 parts by mass of a siloxane-based core/shell elastomer (C) and 0.8 to 10 parts by mass of carbon black (D) with respect to 100 parts by mass of polycarbonate resin (A), the siloxane-based core/shell elastomer (C) has a silicon content of 9.1 to 30 mass % and a number-average particle size in the range of 50 to 1,000 nm, and the flow rate per unit time of the resin composition is 15 to 50 ×10−2 cm3/sec.
US09499693B2 Clean polycarbonate material for use in hard disk drive and semiconductor applications
Compositions based on polycarbonate copolymers to provide ultra-clean materials and articles useful in the hard disk drive and semiconductor industries. In one aspect, the compositions include a polycarbonate copolymer based on a sebacic acid, BPA, PCP polyestercarbonate. The compositions may be used with or without other polymers, fillers or additives. The compositions based on this polycarbonate copolymer exhibit ultra clean performance, low organic contamination, low LPC, and low ionic contaminations. Meanwhile, the compositions also exhibit good flow ability, good ductility and good surface quality.
US09499688B2 Long fiber thermoplastic formed with recycled and renewable content
A molding composition formulation is provided that includes polypropylene, glass fiber, and a polypropylene substitute including recycled sheet molding composition transfer film. The polypropylene substitute is present from 1 to 35 total weight percent also may include natural cellulosic fibers or powders. A process is provided by which the polypropylene substitute is mixed and homogenized and then mixed with polypropylene and additives, and thereafter glass fiber. A reduction in the amount of virgin polypropylene used is reduced compared to conventional thermoplastic glass fiber filled moldings.
US09499683B2 Stabilization of polymers that contain a hydrolyzable functionality
A process for treating a polymer having a hydrolyzable functionality, the method comprising: (i.) providing a polymer having hydrolyzable functionality; and (ii.) introducing a stabilizing agent to the polymer, where the stabilizing agent is defined by the formula (I) where ÷ is a hydrolyzable group that forms an acidic species upon hydrolysis, where R2, R3, and R4 are each independently a halogen atom, a hydrocarbyl group, a hydrocarboxylate group, or a hydrocarbyloxy group.
US09499680B2 Hydroxyethyl cellulose grafted acrylic latex
The present invention relates to latex compositions comprising hydroxyethyl cellulose grafted acrylic polymer emulsions and methods for preparing same without gelling or coagulation. The latex composition comprises at least about 0.2% of HEC by weight relative to the monomer weight, contains at least about 45% solid, and the average mean volume (mV) latex particle size is in the range of about 320-about 850 nm. Paint compositions incorporating the HEC grafted acrylic latex show high viscosity at static conditions and have no color flow and no syneresis compared paints containing a latex without HEC grafting. The present invention also relates to a cross-linking mechanism that cross-links latex particles at ambient conditions. This cross-linking mechanism comprises diacetone acrylamide (DAAM) and methacrylamide (MAM) with or without styrene.
US09499678B2 Fluororubber composition
A fluororubber composition which includes a fluororubber (A) and a carbon black (B). The fluororubber (A) is a vinylidene fluoride-based fluororubber including a structural unit (VdF unit) derived from vinylidene fluoride and a structural unit derived from at least one monomer selected from the group consisting of hexafluoropropylene (HFP), 2,3,3,3-tetrafluoro propylene, and perfluoro(alkyl vinyl ether) (PAVE). The molar ratio of the VdF unit to the structural unit derived from at least one monomer selected from the group consisting of HFP, 2,3,3,3-tetrafluoro propylene, and PAVE is 50/50 to 78/22. The fluororubber composition has a difference δG′ (G′ (1%)-G′ (100%)) of not lower than 120 kPa and not higher than 3,000 kPa, where G′ (1%) denotes a modulus of shearing elasticity at a dynamic strain of 1%, G′ (100%) denotes a modulus of shearing elasticity at a dynamic strain of 100%, and G′ (1%) and G′ (100%) are determined by a dynamic viscoelasticity test.
US09499676B2 Process for producing a syntactically foamed polymer composition, preferably a pressure-sensitive adhesive composition, apparatus for carrying out the process, extrudate and self-adhesive tape
Process for producing a syntactically foamed polymer composition, comprising a) introducing expandable microspheres into a matrix material and mixing in a mixing machine, b) expanding the microspheres, c) the temperature distribution in the mixing machine being inhomogeneous in a plane perpendicular to the transport direction of the machine, d) maintaining the temperature of a first surface bounding the mixing space of the mixing machine, in a plane perpendicular to the transport direction of the mixing machine, at a temperature sufficient for the polymer composition containing the microspheres coming into contact with such first bounding surface to reach a temperature sufficient for commencement and continuation of expansion, e) maintaining a second surface bonding the mixing space in the same plane at a temperature sufficiently low for the polymer composition containing the microspheres coming into contact with it, not to reach a temperature sufficient for commencement and continuation of expansion.
US09499673B2 Method and apparatus for producing a nanocomposite material reinforced by unidirectionally oriented pre-dispersed alumina nanofibers
Method for producing a nanocomposite material reinforced by unidirectionally oriented pre-dispersed alumina nanofibers. The process is suited for industrial-scale production of the nanocomposite materials. The nanocomposite production process involves, synthesis of unidirectionally oriented pre-dispersed alumina nanofibers, casting a mat of pre-dispersed nanofibers with a predetermined orientation in the atmosphere of air or other gas(es) by saturating the nanofibers with liquid polymer matrix. Polymer matrix may include thermosets or/and thermoplastics. The material forming the polymer matrix may be heated to its melting point temperature to transform it to liquid phase. After saturation, the polymer matrix is hardened by lowering its temperature or by means of exposing the polymer matrix to UV radiation, electron beam and/or chemical hardeners. The nanomaterial is composed of polymer composite with homogeneously dispersed uniformly oriented reinforcing nanofibers. Subsequently, the nanofibers in the nanocomposite are dispersed by means of subjecting to hydrodynamic stress, mechanical or/and ultrasound coarse dispersing.
US09499671B2 Hydrophilic polysiloxane compositions containing carbinol groups
Preparation and use of organopolysiloxanes having carbinol groups that are bonded to the silicon atom through carbamate-containing groups. These hydrophilic polysiloxanes can be made to completely dissolve in water or behave as amphoteric surfactants by controlling the concentration of the carbinol radicals and the molecular weight of the polysiloxane.
US09499663B2 Method for producing a polyether ether ketone
A method for producing a polyether ether ketone is disclosed. The method includes the following steps: a) causing a disubstituted benzophenone of the general formula (I) to react with a benzene derivative of the general formula (II), wherein A is a carbon atom provided with a protecting group; R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, each independently of one another, are H, D, OH, X, substituted or unsubstituted C1-C5-alkyl or substituted or unsubstituted C6-C10-aryl; X is F, Cl, Br or I; Z, Z′, Z″, Z′″, each independently of one another, are OH, OMe, Me(OH)m MeR13m or Me; m is 1, 2, 3 or 4; R13 is metal, alkali metal or alkaline earth metal and Me is metal, alkali metal or alkaline earth metal. Subsequently, the product formed in step a) is deprotected in step b) in order to obtain a polyether ether ketone of the general formula (III): wherein G, G′, each independently of one another, are O or C and n is an integer which is greater than 10.
US09499659B2 Liquid hardeners for hardening epoxide resins (I)
The present invention relates to novel latent curing agents for curing curable polymer resins, in particular epoxy resins, and to epoxy resin compositions and the use thereof in the production of fiber composites.
US09499658B2 Polylactic acid resin, preparation method thereof, and packing film comprising the same
The present invention relates to a polylactic acid resin and a packaging film comprising the same, wherein the polylactic acid resin is useful as a packaging material due to excellent properties including heat resistance as well as optimized flexibility. The polylactic acid resin comprises: a hard segment including a predetermined polylactic acid repeating unit; and a soft segment including a polyurethane polyol repeating unit in which certain polyether-based polyol repeating units are linearly connected in a medium of a urethane bond. In addition, the polylactic acid resin has a glass transition temperature (Tg) of 25-55° C.
US09499657B2 Binder for granular and/or fibrous substrates
Binder for granular and/or fibrous substrates.
US09499648B2 Comb polymers which can be used in cosmetics and detergents
A water-soluble copolymer comprising, by mass relative to the total mass of the copolymer: 1 to 40% of at least one cationic monomer; 59.99 to 98% of at least one nonionic monomer; 0.01 to 10% of at least one monomer of formula (I); in which: R1 is a hydrogen atom or a methyl radical; Z is a divalent group —C(═O)—O—, or —C(═O)—NH—; n is an integer between 2 and 200; R2 is a hydrogen atom or a carbon-containing radical which is saturated or unsaturated, optionally aromatic, linear, branched or cyclic, comprising 1 to 30 carbon atoms, and from 0 to 4 heteroatoms chosen from the group comprising O, N and S; the copolymer having a cationic charge density between 0.05 and 3 meq/g.
US09499647B2 Polymer, rubber composition containing polymer, crosslinked rubber composition obtained by crosslinking rubber composition, and tire having crosslinked rubber composition
Provided are: a polymer capable of providing a crosslinked rubber composition with improved durability (i.e., breaking resistance, abrasion resistance, and crack growth resistance) and a method for producing the same, a rubber composition containing the polymer, a crosslinked rubber composition obtained by crosslinking the rubber composition, and a tire having the crosslinked rubber composition. The polymer is either a synthesized polyisoprene or an isoprene copolymer, and contains a residual catalyst in an amount of 300 ppm or less.
US09499643B2 Method for preparing carbene in solution, novel stable form of carbene obtained in particular by means of said method, and uses thereof in catalysis
The invention relates to a method for preparing carbene by means of deprotonation of a precursor salt using a strong base. A purpose of the invention is to enhance the synthesis of carbenes, i.e. to simplify same, to make said synthesis more economical and to obtain a liquid or solid, stable and pure form constituting a catalytic system that is easy to store and use and that has a higher efficiency, higher yield and higher selectivity than carbene catalysts of the prior art. In order to do so, the method comprises deprotonation in a solvent including an alcohol. The invention also relates to an alcohol-containing solution and carbene, and to a solid that can be obtained from the solution, e.g. by means of sublimation.
US09499641B2 Alginate monomer structure with metal crystallite embedded, alginate salt structure with metal crystallite embedded and method of producing alginate hydrogel with metal crystallite incorporated
An alginate monomer structure with metal crystallite embedded includes a first alginate monomer and at least a first metal crystallite. The first alginate monomer is composed of a first uronate molecule and a second uronate molecule, which are linked linearly to each other. A first carbonyl group is formed on a second carbon atom (C2) of the main ring in the first uronate molecule, a carboxyl group is presented on a sixth carbon atom (C6) of the main ring in the second uronate molecule, and a first intramonomer glycosidic linkage is presented between a first carbon atom (C1) of the main ring in the first uronate molecule and a fourth carbon atom (C4) of the main ring in the second uronate molecule. The first metal crystallite is associated between the first uronate molecule and the second uronate molecule.
US09499635B2 Integrated wood processing and sugar production
Provided is a system for localizing and optimizing harvesting of woody biomass by providing a plurality of portable pretreatment units at harvesting or mill sites. The sugars derived from woody waste products can be transported to plants for processing or processing directly by plants located at mill sites to generate biofuels and other chemicals.
US09499634B2 Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
The present invention provides a process and methods for producing asymmetric antibodies in a mammalian expression system. The asymmetric antibodies are transiently or stably expressed and in cells that stably express the asymmetric antibody, following a rapid 2-step process of stable pool to clone, a highly pure asymmetric antibody expressing clone can be identified at a success frequency that permits for screening of tens of clones rather than thousands. The asymmetric antibodies are produced at a high titre and with a high level of purity with no contaminating homodimer antibodies following protein A purification with a step yield of near 100%. Typical downstream purification processes employ standard hydrophobic interaction chromatography (HIC) and/or cation exchange (CEX) resins and the antibody is stable within a wide dynamic range of buffer pH (4-8) and within the requirements for manufacturing antibodies for pre-clinical and clinical applications.
US09499626B2 Antibodies against human CSF-1R and uses thereof
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
US09499625B2 Antibodies against human CSF-1R and uses thereof
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
US09499622B2 Anti-EGFR/anti-HER2 bispecific antibodies with anti-EGFR DARPins
An anti-EGFR/anti-HER2 bispecific antibody including an anti-EGFR DARPin and an anti-HER2 antibody, a pharmaceutical composition including the bispecific antibody, a method of preparing the bispecific antibody, and a method of reducing a side effect and/or enhancing efficacy of an anti-HER2 antibody using an anti-EGFR DARPin.
US09499620B2 Methods of using an alpha-4-beta-7 heterodimer specific antagonist antibody
There are disclosed alpha4beta7 heterodimer-specific antigen binding proteins, nucleic acids encoding them, and methods of making and using them.
US09499614B2 Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of proteins expressed in host cells.
US09499611B2 Anti-NGF compositions and use thereof
The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.
US09499607B2 Anti-dengue virus antibodies and uses thereof
The present invention provides, among other things, antibody agents (e.g., antibodies, and/or antigen-binding fragments thereof) that bind to DV epitopes, as well as compositions containing them and methods of designing, providing, formulating, using, identifying and/or characterizing them. In some embodiments, provided antibody agents show significant binding to a plurality of DV serotypes. In some embodiments, provided antibody agents show significant binding to all four DV serotypes. Such antibody agents are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of DV.
US09499603B2 PD-1 antibodies
A humanised agonistic antibody which binds human PD-1 comprising a heavy chain and a light chain wherein the variable domain of the heavy chain comprises the sequence given in SEQ ID NO:1 for CDR-H1, the sequence given in SEQ ID NO:2 for CDR-H2 and the sequence given in SEQ ID NO:3 for CDR-H3 and the variable domain of the light chain comprises the sequence given in SEQ ID NO:4 for CDR-L1, the sequence given in SEQ ID NO:5 for CDR-L2 and the sequence given in SEQ ID NO:7 for CDR-L3. The invention also extends to therapeutic uses of the antibody molecules, compositions and methods for producing said antibody molecules.
US09499595B2 Development of influenza A antivirals
The present invention includes compositions, methods and systems to isolate and characterize novel antiviral agents by contacting the antiviral agent with the F2F3 zinc fingers of a CPSF30 protein and an Influenza A NS1A protein; and determining whether the binding between the CPSF30 protein and the Influenza A NS1A protein is reduced.
US09499593B2 Modified biotin-binding protein, fusion proteins thereof and applications
The disclosure provides modified biotin-binding proteins which can be expressed in soluble form in high yield in bacteria. Also provided are fusion proteins comprising the modified biotin-binding protein and an antigen. The disclosure further provides non-hemolytic variants of alpha-hemolysin from S. aureus and fusion protein comprising non-hemolytic variant of alpha-hemolysin and a biotin-binding domains. Immunogenic compositions comprising the proteins are also disclosed and use of such immunogenic compositions for inducing an immune response or for vaccinating a subject are also disclosed.
US09499589B2 Chimeric vaccines
The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient.
US09499588B2 Flaviviruses expressing the prM, E, and NS1 proteins of other flaviviruses and uses thereof
This invention provides flavivirus vaccines that comprise live-attenuated flaviviruses and methods of making and using these vaccines. The flavivirus vaccines described herein possess higher potency due to in situ production of additional immunogens in a way that mimics viral infection and the vaccines have potential for higher potency, reducing costs for production and delivery.
US09499587B2 Gamma-AApeptides with potent and broad-spectrum antimicrobial activity
The present invention is directed to a novel class of antimicrobial agents called γ-AApeptides. The current invention provides various categories of γ-AApeptides, for example, linear γ-AApeptides, cyclic γ-AApeptides, and lipidated γ-AApeptides. γ-AApeptides of the current invention are designed to exert antimicrobial activity while being stable and non-toxic. γ-AApeptides also do not appear to lead to the development of microbial resistance in treated microorganisms. Thus, the disclosed γ-AApeptides can be used for the treatment of various medical conditions associated with pathogenic microorganisms.
US09499585B2 Bioactive peptide complexes
Herein disclosed are bioactive peptides and proteins having immunomodulating and antiviral activity, more particularly histidine-rich bioactive peptide complexes having the following structural formula (SEQ ID NO: 23): wherein: X1 is absent or contains not less than 1 amino acid and R1 and R2 are peptide chains containing the amino acid residues His or Cys, that interact with transition metal ions. Whereas R1 may contain up to 5 amino acid residues or alternatively be absent, R2 contains up to 3 amino acid residues or is alternatively absent. Such peptide complexes, primarily alloferon family peptides with Zn ions, enable the design of drugs based on an understanding of drug target structure and thus enable the creation of drugs with targeted mechanism of action.
US09499584B2 GPCR with improved cell surface expression
The present invention surprisingly shows that the addition of a heterologous viral-GPCR (G protein-coupled receptor) derived sequence at the amino terminal end of GPCRs improves cell surface expression of such receptors in eukaryotic cells. Transfected cells expressing the above heterologous viral GPCRs on their surface are useful for cell based assays to identify test compounds that increases or modulate activity of a GPCR or a ligand of a GPCR for example for drug discovery, development of novel flavors in the food industry or development of sensors based on odor GPCRs. In addition, membrane extracts derived from transfected cells may be used for example for assays of compounds in drug discovery or for development of sensors comprising such membrane extracts for identification and/or quantification of volatile organic compounds.
US09499581B2 Compositions comprising enzyme-cleavable oxycodone prodrug
The embodiments provide Compound KC-8, N-1-[3-(oxycodone-6-enol-carbonyl-methyl-amino)-2,2-dimethyl-propylamine]-arginine-glycine-malonic acid, or acceptable salts, solvates, and hydrates thereof. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug, Compound KC-8, that provides controlled release of oxycodone. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of oxycodone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.
US09499579B2 Branched chain-containing aromatic compound
The present invention provides a particular branched chain-containing aromatic compound. The branched chain-containing aromatic compound of the present invention is easily-soluble in isopropyl acetate superior in liquid-separation operability, and can be used for a production method of peptide and the like, which provides a final product simply by extraction separation, without crystallization and isolation of each intermediate in each step.
US09499578B2 Massively parallel synthesis of biopolymeric arrays
Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of branched peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner.
US09499577B2 Natural and synthetic compounds for treating cancer and other diseases
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast, leukocytic, liver, ovarian, bladder, prostatic, skin, bone, brain, leukemia, lung, colon, CNS, melanoma, renal, cervical, esophageal, testicular, spleenic, kidney, lymphatic, pancreatic, stomach and thyroid cancers. This invention is an anti-adhesion therapy which uses the compound as a mediator or inhibitor of adhesion proteins and angiopoietins. It inhibits excess adhesion and inhibits cell attachment. It modulates angiogenesis. The compounds also use as mediator of cell adhesion receptor, cell circulating, cell moving and inflammatory diseases. The compounds are attached with angeloyl, acetyl, tigloyl, senecioyl, Crotonoyl, 3,3-Dimethylartyloyl, Cinnamoyl, Pentenoyl, Hexanoyl, benzoyl, Ethylbutyryl, benzoyl, dibenzoyl, alkanoyl, alkenoyl, benzoyl alkyl substituted alkanoyl, ethanoyl, propanoyl, propenoyl, butanoyl, butenoyl, pentanoyl, hexenoyl, heptanoyl, heptenoyl, octanoyl, octenoyl, nonanoyl, nonenoyl, decanoyl, decenoyl, propionyl, 2-propenoyl, 2-butenoyl, Isobutyryl, 2-methylpropanoyl, 2-ethylbutyryl, ethylbutanoyl, 2-ethylbutanoyl, butyryl, (E)-2,3-Dimethylacryloyl, (E)-2-Methylcrotonoyl, 3-cis-Methyl-methacryloyl, 3-Methyl-2-butenoyl, 3-Methylcrotonoyl, 4-Pentenoyl, (2E)-2-pentenoyl, Caproyl, 5-Hexenoyl, Capryloyl, Lauroyl, Dodecanoyl, Myristoyl, Tetradecanoyl, Oleoyl, O—C(2-18) Acyl.
US09499576B2 Compound, nucleic, acid, method for producing nucleic acid, and kit for producing nucleic acid
The present invention relates to a compound represented by Formulas 1, 2 or 3 as described herein, and a nucleic acid each of which contains a dye exhibiting an exciton effect, a method of producing such a nucleic acid by using the compound, and a kit for producing the nucleic acid.
US09499574B2 Arsenoplatin anti-cancer agents
Disclosed are compound having the structure of formula (I): wherein M is Pt, Pd or Ni; Q is As, Sb or Bi; Z1 is N; Z2 is O or S; L1 and L2 are independently C(O), C—R1 or C—R2; X is a Lewis base and Y1 and Y2 are independently oxygen- or sulfur-containing substituents, conjugates containing compounds of formula (I) and their use as chemotherapy agents.
US09499572B2 Phosphatidylalkanols and compositions thereof
The present invention discloses a composition comprising a compound of formula I and a deuterated solvent. The deuterated solvent is miscible with water in any proportion at a temperature of 20 to 25° C. and comprises less than 5% residual 1H-isotopes. The concentration of the compound of formula I may advantageously be determined by 1H-QNMR. Methods of production of the composition and salts of compounds of formula I, as well as related analogs and novel reagents and intermediates for the production thereof, are also described.
US09499566B2 Oxidation process for preparing 3-formyl-cephem derivatives
The present invention relates to an improved process for oxidizing 3-hydroxy-methyl-cephem derivatives to the corresponding 3-formyl-cephem derivatives. In particular this oxidation process is for the preparation of 7-[2-(5-amino-[1,2,4]thia-diazol-3-yl)-2-hydroxyimino-acetylamino]-3-formyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid derivatives of formula (I) using a combination of a hypervalent iodine oxidizing agent of the type 10-I-3 such as bis(acetoxy)iodo-benzene (BAIB) and a catalyst such as 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO). These compounds of formula (I) are intermediates in the synthesis of ceftobiprole.
US09499560B2 N-containing heterocyclic compounds
The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.
US09499559B2 Method for preparing long-chain alkyl cyclic acetals made from sugars
Long-chain alkyl cyclic acetals made from sugars are obtainable by a method that comprises the steps consisting of: dehydrating a hexitol in a monoanhydrohexitol substrate; reacting the monoanhydrohexitol substrate obtained with an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of an acetalization reaction with a substrate/reagent ratio of between 5:1 and 1:1, or with a derivative of an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of a transacetalization reaction with a substrate/reagent ratio of between 1:1 and 1:3, in the presence of acid catalyst and in an environment that is free of solvent or that consists of non-aqueous polar solvent; collecting the long-chain alkyl acetal of hexitan from the mixture obtained.
US09499556B2 Convenient preparation of N-substituted morphinan-6-ols from morphinan-6-ones
Described herein are methods of preparing 6-hydroxy N-alkyl morphinan-6-ols from morphinan-6-ones, as illustrated below: wherein the variables R1, R2, R3, R10, R11, R14, and are as defined herein and wherein the reactions occur in a one-pot procedure using a boron based reducing agent.
US09499555B2 Porous crystalline frameworks, process for the preparation therof and their mechanical delamination to covalent organic nanosheets (CONS)
The invention disclosed herein provides, Porous Crystalline Frameworks (PCFs) also known as Covalent Organic Frameworks (COFs) that exhibit stability towards acidic, basic and neutral pH conditions. Further the invention discloses economical, environmentally-friendly process for the synthesis thereof.
US09499554B2 Anti-influenza compositions and methods
Disclosed are novel compounds comprising an imino-ribose derivative covalently linked to a carbocycle or heterocycle. Pharmaceutical compositions comprising the compounds of the invention are also described. Methods of inhibition, treatment and/or suppression of viral infections with the compounds of the invention are also described. The compositions or methods may optionally comprise one or more additional anti-viral agents.
US09499553B2 Dihydropyridazine-3,5-dione derivative and pharmaceuticals containing the same
The present invention provides a dihydropyridazine-3,5-dione derivative or a salt thereof, or a solvate of the compound or the salt, a pharmaceutical drug, a pharmaceutical composition, a sodium-dependent phosphate transporter inhibitor, and a preventive and/or therapeutic agent for hyperphosphatemia, secondary hyperparathyroidism, chronic renal failure, chronic kidney disease, and arteriosclerosis associated with vascular calcification comprising the compound as an active ingredient, and a method for prevention and/or treatment.
US09499552B2 Pyrazolo[1,5-A]pyrimidine derivative and use of anti-tumor thereof
The present invention relates to a pyrazolo[1,5-a]pyrimidine derivative of general formula 1 and a pharmaceutically acceptable salt thereof. The present invention also relates to use of compounds of formula 1 in the preparation of an anti-tumor medicament.
US09499549B2 Pyrrolo[3,2-]pyrimidine derivatives for the treatment of viral infections and other diseases
This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
US09499545B2 Piperidinone carboxamide azaindane CGRP receptor antagonists
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
US09499543B2 Polymorph forms
The present invention relates to novel crystal forms of 2-amino-N-[2-(3a-(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-1-(R)-benzyloxymethyl-2-oxo-ethyl]-isobutyramide L-tartrate. More particularly, the invention relates to polymorph forms, and to processes for the preparation of compositions containing and to uses of such polymorph forms.
US09499539B2 Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway
The invention relates generally to the creation and use of cyclic sulfonamide containing derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds for the treatment of hyperproliferative diseases and angiogenesis mediated diseases.
US09499538B2 Estrogen receptor modulators and uses thereof
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
US09499537B2 Antiviral pyrrolopyridine derivatives and method for preparing the same
The present invention relates to a pyrrolopyridine derivative represented by the Chemical Formula I, and a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and relates to an antiviral composition including the same as an active ingredient. The compound of the Chemical Formula I has excellent antiviral activity and selectivity for wild type and resistant HIV-1, and thereby is useful as a therapeutic agent for acquired immune deficiency syndrome (AIDS).
US09499535B2 Kinase inhibitors
The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases.
US09499534B2 Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors
The invention provides certain thiazole-substituted aminopyrimidine compounds of the Formula (I) (I), or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R5, R6, and the subscripts r, s, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
US09499532B2 Therapeutic compounds and compositions
The present invention provides compounds and compositions that inhibit Factor XIa or kallikrein and methods of using these compounds and composition.
US09499531B2 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazolyl, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3-a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3-b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.
US09499529B2 Therapeutic uses of curcumin analogs for treatment of prostate cancer
This invention relates generally to methods of treating aggressive cancers, such as hormone-refractory metastatic prostate cancer, by exposing the aggressive cancer cells to curcumin analogs having the claimed structural scaffolds and side groups. The anticancer effects of curcumin are associated with its influence on numerous growth factors within the cells. However, its clinical development has been limited by its suboptimal pharmacokinetics and poor bioavailability caused by poor solubility in water and rapid in vivo metabolism. There is the need to develop new and improved curcumin analogs with better potency, water solubility, and in vivo metabolic stability, as well as retained safety profiles. Curcumin analogs having one of the claimed four novel scaffolds with basic heteroaromatic side groups show the ability to decrease aggressive cancer cell viability and to inhibit aggressive cancer cell growth.
US09499528B2 Class of near infrared molecular probes for biological applications
Methods for preparing 2,5-Bis(benzoxazol-2′-yl)benzene-1,4-diol derivatives (Zinhbo derivatives) are provided. Zinhbo derivatives are used to detect zinc ions and have particular application in vivo and in vitro. Zinhbo derivatives upon excitation give a florescence response emission that can be used to determine the presence of zinc cation in solution. Zinhbo derivatives complexed with zinc cations upon excitation can produce a florescence response emission in the visible and near infrared range. Zinhbo derivatives complexed with zinc cations exhibit a large stoke shift between the excitation and emission wavelengths.
US09499526B2 Compositions and methods for the treatment of neurologic diseases
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of neurologic diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of depression, Alzheimer's disease, multiple sclerosis, Batten disease, multiple sclerosis, Parkinson's disease (PD) and restless legs syndrome (RLS).
US09499523B2 Phosphatidylinositol 3-kinase inhibitors
The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein n, m, R1, R2, R3, R4, and R5 are described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.
US09499521B2 Inhibitors of cellular necrosis and related methods
A compound having the following structure (I): or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.
US09499520B2 Process for the preparation of voriconazole and analogues thereof
The present invention provides a process for preparing a compound of formula: (Formula XI and XII) (XI) (XII) wherein X, Y, Z, A, B and E are as defined herein, by reacting a compound of formula: (Formula XIII) (XIII) with a compound of formula: (Formula XIV and XV) (XIV) (XV) respectively, in the presence of a transition metal catalyst, a ligand suitable for use with 15 the catalyst and a reducing agent. The invention also provides novel intermediates.
US09499516B2 Nitrogen-containing heterocyclic compound
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like.The present invention relates to a compound represented by the formula (I) or a salt thereof. wherein each symbol is as described in the specification, or a salt thereof.
US09499514B2 Antiproliferative compounds and methods of use thereof
Compounds of formula I for treating, preventing or managing cancer are disclosed. Also disclosed are methods of treating, preventing or managing cancer, such as leukemia, comprising administering the compounds. In certain embodiments, the method of treatment comprise administering a compound provided herein in combination with a second agent. Pharmaceutical compositions and single unit dosage forms comprising the compounds are also disclosed.
US09499513B2 Acid generators and photoresists comprising same
Acid generator compounds are provided that are particularly useful as photoresist composition components. Preferred acid generators include cyclic sulfonium compounds that comprise a covalently linked acid-labile group.
US09499512B2 Process for producing a cyclic acetal in a heterogeneous reaction system
A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a cyclic acetal such as trioxane. The catalyst, for instance, may comprise a solid catalyst such as an ion exchange resin. In one embodiment, the process is used for converting anhydrous formaldehyde gas to trioxane. The anhydrous formaldehyde gas may be produced form an aqueous formaldehyde solution by an extractive distillation.
US09499511B2 N-substituted hydroxylamine derivatives with carbon-based leaving groups
The disclosed subject matter provides certain N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or development of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.
US09499509B2 Dihydrochalcone derivatives and their use as antibiotic agents
A compound of formula (I) as well as pharmaceutical compositions comprising same is provided. An extract of a plant belonging to a species of Populus, the extract comprising this compound is also provided. These can be used as antibacterial for treating bacterial infection.
US09499506B2 Method for preparing 2,5-furandicarboxylic acid
A method for preparing 2,5-furandicarboxylic acid (FDCA) by oxidizing 5-hydroxymethylfurfural (HMF) in water in the presence of a weak base and a supported catalyst comprising platinum and bismuth, in which the Bi/Pt molar ratio in the catalyst is between 0.1 and 0.3, and preferably between 0.15 and 0.3.
US09499504B2 Crystalline form of vortioxetine hydrobromide
The present invention is directed to a crystalline compound comprising a hydrobromide acid (HBr) salt of a compound of formula (I) (1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine, INN: vortioxetine), having an XRPD pattern with characteristic peaks (expressed in 2θ±0.2° 2θ (CuKα radiation)) at 5.5°, 14.8°, 16.7° and 20.0° and processes for obtaining the same.
US09499503B2 Mitotic kinesin inhibitors and methods of use thereof
This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors.
US09499501B2 2-Mercaptobenzothiazole manganese zinc, preparation method therefor and application thereof
The present invention belongs to the technical field of agricultural fungicides and discloses a 2-mercaptobenzothiazole manganese zinc, preparation method therefor and application thereof. The chemical structure of the 2-mercaptobenzothiazole manganese zinc is shown as the above formula. Wherein m, n and n′ are positive integers, m=2(n+n′), n≧n′, n:n′=1:1˜9:1. Materials are prepared according to the stoichiometric ratio of the target products; 2-mercaptobenzothiazole is dissolved in sodium hydroxide solution. The aqueous solution of water-soluble manganese salts and water-soluble zinc salts solution are successively added to 2-mercaptobenzothiazole sodium solution under stirring, followed by stirring for mixing well, then the solution being allowed to stand, filtered and washed with water to obtain filter cake, and then dried in vacuum to obtain 2-mercaptobenzothiazole manganese zinc. The present 2-mercaptobenzothiazole manganese zinc may be used as an agricultural fungicide. The present invention coordinates the surface of solid particles of 2-mercaptobenzothiazole manganese with zinc to form a stable clathrate of 2-mercaptobenzothiazole manganese and zinc. Tests show that the clathrate has excellent effect for controlling a plurality of diseases including apple alternaria leaf spot, pear scab, apple ring rot, apple anthracnose and the like.
US09499499B2 Valsartan salts
The invention relates to new salts of valsartan or crystalline, also partly crystalline and amorphous salts of valsartan, the respective production and usage, and pharmaceutical preparations containing such a salt.
US09499493B2 2,4-pyrimidinediamine compounds and their uses
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
US09499490B2 Fluorophenyl pyrazol compounds
The present invention provides a compound of the Formula: wherein X is selected from the group consisting of, R is selected from the group consisting of H and CH3; R1 is selected from the group consisting of H, CH3, F, Cl, OCH3, C(O)OH, C(O)NH2 or a pharmaceutically acceptable salt thereof.
US09499486B2 Kinase inhibitor
There is provided a compound of formula I, which compound has anti-inflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and has use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
US09499484B2 Indole, indoline derivatives, compositions comprising them and uses thereof
The invention provides indole and indoline derivatives and slats thereof, compositions comprising them and uses thereof for the treatment of diseases and disorders.
US09499482B2 Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are melanin concentrating hormone receptor-1 (MCHR1) antagonists which may be used as medicaments.
US09499476B2 Acetamide stereoisomer
The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like. Processes for making the compound of formula (I), as well as related intermediates, are disclosed.
US09499473B2 Method for producing nitrous acid ester, and method for producing dialkyl oxalate and dialkyl carbonate
A method for producing nitrous acid ester in which nitric oxide, oxygen, and an alcohol are reacted, thereby generating nitrous acid ester includes a step of generating nitrous acid ester by supplying a bottom liquid from a bottom part of the reaction column, and nitric oxide and/or carbon monoxide, a step of supplying nitrous acid ester to the reaction column; a step of supplying a reaction liquid containing water, nitric acid, and the alcohol to a nitric acid condensing column from the reactor; and a step of separating a low-boiling point component by distillation from the reaction liquid under control of a concentration of the alcohol in a condensed liquid being generated at a bottom part of the nitric acid condensing column to be less than 4.0% by weight so as to introduce the condensed liquid into the reactor from the nitric acid condensing column.
US09499472B2 Aspartylamide inhibitors of excitatory amino acid transporters
The compounds of the invention are inhibitors of excitatory amino acid transporters (EAAT) that penetrate the blood-brain barrier to access the central nervous system. The compounds of the invention follow the structural formula: or a salt, ester or prodrug thereof, wherein X is a halogen, such as fluorine, or a radionuclide, such as fluorine-18. The compounds and methods described herein can be used for the treatment of, e.g., neurodegenerative disorders (e.g., amyotrophic lateral sclerosis), ischemia, spinal cord injury, and traumatic brain injury in a patient (e.g., a human). The invention further provides compounds and methods for the synthesis and use of radiographic tracers to diagnose and follow the progression of such disorders.
US09499470B2 Process for the carbonylation of dimethyl ether
Process for preparing methyl acetate by the carbonylation of dimethyl ether with carbon monoxide in the presence of hydrogen and a zeolite catalyst. In a first step, the carbonylation is conducted with a carbon monoxide to hydrogen molar ratio of at least 1 and, in a second and subsequent step, the carbonylation is conducted with a hydrogen to carbon monoxide molar ratio of greater than 1.
US09499467B2 Ortho-fluoro substituted compounds for the treatment of metabolic diseases
There is provided novel fluoro-substituted compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as type II diabetes, hypertension, ketoacidosis, obesity, glucose intolerance, and hypercholesterolemia and related disorders associated with abnormally high or low plasma lipoprotein, triglyceride or glucose levels.
US09499464B2 Opsin-binding ligands, compositions and methods of use
Compounds are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic is visual cycle products that accumulate in the eye, such as dry adult macular degeneration, as well as conditions caused by or related to the misfolding of mutant opsin proteins and/or the mis-localization of opsin proteins. Compositions of these compounds alone or in combination with other therapeutic agents are also described, along with therapeutic methods of using such compounds and/or compositions. Methods of synthesizing such agents are also disclosed.
US09499463B2 Mixtures of constitutionally isomeric bisphosphites
The invention relates to mixtures of constitutional isomer bisphosphites of formulae (1a) and (2a), to a method for the production thereof, to the reaction thereof with metals to form mixtures containing complex compounds of the constitutional isomer bisphosphites of formulae (1a) and (2a) and the metal, and to the use thereof as a catalytically active composition in hydroformylation reactions. Said hydroformylactically active compositions comprises, in addition to the complex compounds of metal and the constitutional isomer bisphosphites of formulae (1a) and (2a), non-bound bisphosphites of the constitutional isomer bisphosphites of formulae (1a) and (2a) and at least one additional component.
US09499459B2 Materials for organic electroluminescent devices
The present invention relates to substituted benz[a]anthracene derivatives, to the preparation and use thereof in organic electroluminescent devices, and to organic electroluminescent devices, in particular blue-emitting devices, in which these compounds are used as matrix material or dopant in the emitting layer and/or as hole-transport material and/or as electron-transport material.
US09499456B2 Tetramerisation of ethylene
A process for the tetramerisation of ethylene under solution phase conditions is carried out in the presence of an activated catalyst at a temperature above 80° C. and up to a temperature of about 115° C. The activated catalyst is provided by combining a source of chromium, a diphosphine ligating compound and optionally a catalyst activator or combination of catalyst activators. The process forms at least 30% 1-octene and a polyethylene co-product that, together with any other reaction products, remains substantially dissolved in the liquid phase. The polyethylene co-product has a weight average molecular weight (Mw) of less than 200 000 g/mol, a number average molecular weight (Mn) of less than 3 000 g/mol, and a melt flow index of more than 20 g/10 minutes.
US09499451B2 Soil conditioner compositions containing lignocellulosic biomass fermentation process syrup
Syrup produced in a lignocellulosic biomass fermentation process is used as a binder for soil conditioning materials to make an agricultural composition that is easily handled and applied. The syrup binds powdery soil conditioning materials such as lime and gypsum to form pellets or granules.
US09499450B2 Electrostatic adhesion of dry powders to macro fertilizers
A method for electrostatically adhering an agricultural input powder to an agronomic carrier is described. A dry nutrient powder is electrostatically charged in a charging chamber which has a grounded metal component such that the electrostatically charged powder moves towards the metal component. The agronomic carrier is then passed by the charged powder such that the charged powder adheres to the carrier.
US09499438B2 Window for attenuating RF and IR electromagnetic signals
Windows for attenuating radio frequency (RF) and infrared (IR) electromagnetic signals, so as to prevent or reduce such signals from emanating from secure facilities (e.g., government and/or military facilities). Example embodiments relate to a window including at least first and second glass substrates, at least first and second low-emissivity (low-E) coatings for blocking at least some IR and RF signals, and at least one transparent conductive oxide (TCO) inclusive coating for blocking at least some RF signals. The TCO inclusive coating may include a layer of or including indium-tin-oxide (ITO) located between at least first and second dielectric layers.
US09499437B2 Coated article with low-E coating having multilayer overcoat and method of making same
A coated article is provided so as to include a low-E (low emissivity) coating having an infrared (IR) reflecting layer(s) of or including a material such as silver (Ag), which is provided between a pair of contact layers. The low-E coating includes an overcoat having at least one layer of or including zirconium oxide and/or a substantially metallic layer. The overcoat has been found to improve the durability of the coating without significantly sacrificing desired optical characteristics. Such coated articles may be used in the context of windows.
US09499436B2 Light scattering coating for greenhouse applications, and/or coated article including the same
Certain example embodiments relate to a sunlight-scattering thin-film coating disposed on a substrate for greenhouse applications. The surface morphology of the coating promotes a better and more uniform light distribution. For instance, at least one thin-film layer disposed on a substrate may be textured so as to create surface features on the order of 0.1-5 microns, with the surface features being sized to cause (a) light having a wavelength of greater than or equal to about 800 nm incident thereon to primarily scatter to angles less than 30 degrees relative to a major surface of the substrate and (b) light having a wavelength of less than or equal to about 700 nm incident thereon to primarily scatter to angles greater than 20 degrees relative to the major surface of the substrate. This arrangement may advantageously direct beneficial light towards plant life while directing parasitic light away from the plant life.
US09499433B2 Heat treatable article with printed coating thereon, and/or method of making the same
Certain example embodiments of this invention relate to coated articles including substrates that support printed patterns and thin film layer stacks that can have the patterns and the layer stacks formed thereon and then be cut, heat treated, and optionally built into an insulated glass unit, laminated to another substrate, and/or used in another product. In certain example embodiments, this is made possible by bonding to the glass the frit material used in forming the pattern, re-annealing the glass following the bonding, disposing the thin film layer stack on the re-annealed substrate supporting the bonded pattern, and then cutting and heat treating. The frit advantageously does not re-melt during heat treatment because the melting temperature is higher than the temperature used in heat treatment, and/or as a result of secondary recrystallization of the frit material. Associated methods also are provided.
US09499431B2 Strengthened glass articles and methods of making
A strengthened glass article having a central tension that is below a threshold value above which the glass exhibits frangible behavior. The central tension varies non-linearly with the thickness of the glass. The glass article may be used as cover plates or windows for portable or mobile electronic devices such as cellular phones, music players, information terminal (IT) devices, including laptop computers, and the like.
US09499430B2 Sintering apparatus and sintering method for glass preform for optical fiber
A sintering apparatus heat-treats a porous glass preform for an optical fiber at a high temperature. The sintering apparatus includes: a glass preform elevating/lowering mechanism; a furnace core tube having an upper part having an opening part into which the glass preform is inserted by the elevating/lowering mechanism, and made of quartz glass; a heating furnace disposed on an outer circumference of the furnace core tube; an upper lid for closing the opening part of the furnace core tube; and a sealing member holding mechanism included in the upper lid and configured to hold a sealing member interposed between the opening part and the upper lid.
US09499427B2 Articulated bending support
A process for gravity bending of a glass sheet on a support including a chassis, a first frame and a second frame, the second frame being articulated and including a mobile lateral part that passes from an open position to a closed position by an articulation during the bending procedure, the bending of the sheet beginning on the first frame while the second frame is in the open position, and finishing on the second frame in the closed position, the sheet passing from the first frame to the second frame during the bending procedure as a result of the relative vertical movement of the first and second frame and of the raising of the mobile part of the second frame, the contact area of the first frame with the glass sheet located in a vertical line with the articulation being above the articulation at the instant the latter is closed.
US09499425B2 Method of fabricating a multi-tone glass vessel from at least two disparately-colored gobs
A method of fabricating a multi-tone glass vessel includes depositing a molten-glass first gob of a first glass color into a mold having a lower end and an upper end. An initial quantity of gas is injected into the mold in order to form a gob cavity within the first gob and cause the first gob to partially inflate and expand toward the upper end of the mold. A molten-glass second gob of a second glass color is deposited into the mold over the partially-inflated first gob. The introduction of a second quantity of gas into the gob cavity within the mold forms the first and second gobs into a single, multi-tone vessel of predetermined shape.
US09499421B2 Method and apparatus for removing chloride from samples containing volatile organic carbon
A method for removing chloride from samples containing volatile organic carbon, wherein a chloride containing sample is mixed with a difficulty volatile acid, wherein hydrochloric acid gas arises, which is present in dissolved form in a sample-acid mixture and then the hydrochloric acid gas is purged by a carrier gas from the sample-acid mixture, wherein the hydrochloric acid gas is removed from the carrier gas following the purging and the carrier gas is fed back to the sample-acid mixture. In order during the hydrochloric acid purging largely to suppress the driving out of easily volatile organic compounds, the sample-acid mixture has a temperature of approximately 3° C. to 30° C., wherein, following the purging from the sample-acid mixture, the hydrochloric acid gas is removed from the carrier gas by absorption with water.
US09499420B2 Formulations and methods for removing heavy metals from waste solutions containing chelating agents
Described are chemical formulations that remove heavy metals from waste solutions containing a chelating agent. Also disclosed are methods for removing heavy metals from waste solutions utilizing such chemical formulations.
US09499417B1 Adjustable water softener with closed-pressure aeration
A water conditioning system that both softens and improves the smell of water by removing dissolved ferrous iron and hydrogen sulfide from the water includes: a water softening tank, a cation exchange media situated in the water softening tank, a brine tank, a programmable control valve which regulates flow through the system and the periodic rejuvenation of the cation exchange media using flow from the brine tank, a valve that assists in providing a flow of aerated, pressurized water to the system, and an adapter with a bottom portion and a flow control valve that control the volume of the gaseous pocket that is created in the top portion of the water softening tank.
US09499414B1 Method of dye removal from wastewater
A method of dye removal from wastewater includes producing activated carbon from heavy oil fly ash and using the activated carbon to adsorb dye in the wastewater. The heavy oil fly ash based activated carbon is produced using phosphoric acid based chemical activation. The dye can be removed from wastewater by contacting the wastewater with the activated carbon. The activated carbon can then be separated from the wastewater to remove the dye, and thereby, purify the wastewater.
US09499413B2 Evaporator array for a water treatment system
An evaporator array for a water treatment system, the evaporator array comprising a produced water feed and a first evaporator to receive produced water from the produced water feed, a makeup water feed and a second evaporator to receive makeup water from the makeup water feed, an output feed to receive distillate from the first evaporator and the second evaporator, and a blowdown feed to receive blowdown from the first evaporator and the second evaporator, wherein the first evaporator and the second evaporator each have a working pH, the working pH of the first evaporator being higher than that of the second evaporator.
US09499410B2 Methods and compositions for making metal oxide-graphene composites
Methods of making a metal oxide-graphene composite are disclosed. The method can include, for example, providing a composition including graphene oxide and at least one elemental metal dispersed in a liquid medium, and heating the composition in a sealed chamber at a temperature above a nominal boiling point of the liquid medium to form the metal oxide-graphene composite. Compositions useful for performing the process and composites obtained by the process are also disclosed.
US09499408B2 Graphene sheets and methods for making the same
The invention relates to graphene sheets and to a method for making the same in which a solution of graphene or graphite oxide is applied to a blue steel substrate and dried.
US09499407B2 Carbon and carbon/silicon composite nanostructured materials and casting formation method
The invention provides nanostructure composite porous silicon and carbon materials, and also provides carbon nanofiber arrays having a photonic response in the form of films or particles. Composite materials or carbon nanofiber arrays of the invention are produced by a templating method of the invention, and the resultant nanomaterials have a predetermined photonic response determined by the pattern in the porous silicon template, which is determined by etching conditions for forming the porous silicon. Example nanostructures include rugate filters, single layer structures and double layer structures. In a preferred method of the invention, a carbon precursor is introduced into the pores of a porous silicon film. Carbon is then formed from the carbon precursor. In a preferred method of the invention, liquid carbon-containing polymer precursor is introduced into the pores of an porous silicon film The precursor is thermally polymerized to form a carbon-containing polymer in the pores of the porous silicon film, which is then thermally carbonized to produce the nano structured composite material. A carbon nanofiber array is obtained by dissolving the porous silicon. A carbon nanofiber array can be maintained as a film in liquid, and particles can be formed by drying the material.
US09499406B1 Methods for the additive manufacturing of semiconductor and crystal materials
A method for the additive manufacturing of inorganic crystalline materials, including: physically combining a plurality of starting materials that are used to form an inorganic crystalline compound to be used as one or more of a semiconductor, scintillator, laser crystal, and optical filter; heating or melting successive regions of the combined starting materials using a directed heat source having a predetermined energy characteristic, thereby facilitating the reaction of the combined starting materials; and allowing each region of the combined starting materials to cool in a controlled manner, such that the desired inorganic crystalline compound results. The method also includes, prior to heating or melting the successive regions of the combined starting materials using the directed heat source, heating the combined starting materials to facilitate initial reaction of the combined starting materials. The method further includes translating the combined starting materials and/or the directed heat source between successive locations. The method still further includes controlling the mechanical, electrical, photonic, and/or optical properties of the inorganic crystalline compound.
US09499405B2 Process for producing sulfuric acid with low levels of niter
This disclosure relates to a process for producing sulfuric acid with reduced levels of niter. The process involves (a) providing an absorption tower wherein sulfur trioxide is absorbed in a sulfuric acid feed having a first sulfuric acid solution to produce a sulfuric acid effluent having (i) a second sulfuric acid solution which has a higher concentration than the first sulfuric acid solution, (ii) a niter concentration greater than about 5 ppm (as NO3), and (iii) a temperature greater than 100° C.; and (b) contacting a first purifying agent comprising sulfamic acid and a second purifying agent comprising hydrogen peroxide with the sulfuric acid effluent to form a treated sulfuric acid effluent, the treated sulfuric acid effluent being maintained at a temperature of greater than 100° C. for a maintenance period of at least about 1 minute.
US09499402B2 Method for preparing a supported ruthenium catalyst
In a method of preparing a ruthenium-containing catalyst on a non-conductive metal oxide support comprises dissolving one or more ruthenium precursor compounds in an liquid organic polyol, combining the thus obtained solution with (a) nano-powder(s) of one or more metal oxides in a ratio of moles metal oxide(s) to moles ruthenium atoms in the one or more ruthenium precursor compounds of about 0:1 to about 6:1, the metal oxide nano-powder(s) having a surface area of from about 5 to about 300 m2/g and a point of zero charge (PZC) of pH 5.5 or higher, agitating the thus obtained mixture, adding pre-shaped alumina support pellets to the agitated mixture, which is than heated at a temperature of about 50° C. to the boiling point of the organic polyol, until the reaction is finished, cooling the mixture and combining it with an aqueous solution of NaNO3 and/or KNO3, agitating the resultant mixture, separating the solvent and the solids, and drying the thus obtained solid pellets of alumina, or alumina and the metal oxide(s) of the nano-powder(s) coated with ruthenium and an additional amount Na and/or K ions. Also disclosed is the supported ruthenium-containing catalyst obtainable by the method and the use thereof in decomposing ammonia into nitrogen and oxygen.
US09499393B2 Stress relief MEMS structure and package
Stress relief structures and methods that can be applied to MEMS sensors requiring a hermetic seal and that can be simply manufactured are disclosed. The system includes a sensor having a first surface and a second surface, the second surface being disposed away from the first surface, the second surface also being disposed away from a package surface and located between the first surface and the package surface, a number of support members, each support member extending from the second surface to the package surface, the support members being disposed on and operatively connected to only a portion of the second surface. The support member are configured to reduce stress produced by package-sensor interaction.
US09499392B2 CMOS ultrasonic transducers and related apparatus and methods
CMOS Ultrasonic Transducers and processes for making such devices are described. The processes may include forming cavities on a first wafer and bonding the first wafer to a second wafer. The second wafer may be processed to form a membrane for the cavities. Electrical access to the cavities may be provided.
US09499386B2 Wine storage and dispensing apparatus
An apparatus for storing and dispensing wine comprises a housing formed substantially in the shape of a wine barrel. The housing including a circumferential wall, a first closed end and a second open end. A spigot for selectively dispensing wine is supported by and positioned through the first closed end of the housing. A removable insert disposable within the housing through the second open end contains a collapsible bladder of wine. A wine dispensing port is contained within the bladder and insert. With the insert positioned within the housing, the port is positioned proximate the second open end thereof. A conduit in fluid communication with the spigot extends from the first closed end toward the second open end. Upon disposing the insert within the housing, the conduit is connectable to the port wherein the wine can be selectively dispensed from the spigot.
US09499385B1 System and method for brewing and dispensing coffee using customer profiling
A system and method for brewing and dispensing beverages may use customer profiling to select beverages to be produced and presented to a given customer and/or messages to be displayed to the customer, based on customer-specific information stored on a loyalty card, in a local system, or remotely. A user interface mechanism may receive input identifying the given customer. A controller may select a base drink recipe dependent on the customer's identity, and may initiate production of a beverage using the selected drink recipe. Each drink recipe may specify an amount of water, coffee, flavorings, dairy, and/or other ingredients, and may be further customizable to add or remove ingredients and/or to change an amount thereof, based on received user input. The stored customer-specific information may include a customer identifier, account information, a purchase history, a message history, drink recipes, and/or an email address for each of a plurality of customers.
US09499384B2 Hands free, controlled autofill for a dispenser
A dispensing system includes one or more digital image capture devices for capturing images in a dispenser well and a digital image analyzer operatively coupled to the digital image capture device(s) for analyzing the images for use in regulating a dispensing operation. The digital image analyzer evaluates digital images captured by the digital image capture device(s) to determine various characteristics of a container placed in the dispensing well, such as the height and position of the container.
US09499382B2 Systems and methods for monitoring and controlling the dispense of a plurality of product forming ingredients
Systems and methods for dispensing a product are provided. A plurality of product ingredients are associated with a product dispenser that is operable to form a plurality of selectable products from the plurality of products ingredients. Input for a selected product is received and a recipe that defines the ratio of product ingredients for fainting the selected product is identified. The dispense of each of the respective product ingredients is commenced based at least in part on the identified recipe, and the dispense of each of the respective product ingredients is independently monitored during the dispense of the selected product.
US09499381B2 Bung plug extractor and methods for transferring fluid with a pressurized tank
An apparatus for exchanging fluid with a tank through a tank port includes a bung extractor casing that has a first end configured to removably couple to a tank port. The tank port is configured to be sealingly coupled to a bung plug. The bung extractor casing also includes a second end opposite the first end, a hose connector configured to removably couple to a hose, and a channel defined between the first end and the hose connector. The apparatus also includes a bung extractor coupled to the extractor casing second end. The bung extractor includes a tip portion configured to releasably engage the bung plug. The bung extractor is operable to selectively uncouple the bung plug from the tank port such that a sealed flow path is formed through the tank port and the channel.
US09499380B1 Hook attachment for a forklift vehicle
A hook attachment for a forklift vehicle including a hook having a rectangular upper half and a hooked lower half, a rectangular aperture disposed within the upper half of the hook, and a lip medially disposed within the aperture on an internal surface of a top edge of the upper half. A length of the aperture substantially conforms to a width of a fork on a forklift vehicle. The upper half of the hook is configured to slidably engage the fork through the aperture. The lip is configured to securingly engage an opening in a top side of the fork.
US09499378B2 Process and structure for servicing a vehicle
A support and a process for a non-automotive vehicle to be lifted by a car lift and allow for servicing of the vehicle. The support can include a support surface that has an engine access opening and a rolling mechanism attached to the support surface that affords for the support surface to roll into a service area that has a car lift. The car lift can be a two-post car and the support spans the distance between lift arms of the car lift. Once the support with a vehicle thereon is lifted above a service area floor vehicle, the engine of the vehicle can be serviced through the engine access opening. In this manner, non-automotive vehicles can be easily and quickly serviced in traditional automotive service areas, shops, etc.
US09499376B2 Turnaround mechanism for passenger conveyors
A turnaround mechanism for a passenger conveyor may include a turnaround track for facilitating a smooth transition of a plurality of pallets between a passenger side and a return side. Each of die plurality of pallets may have a front end portion engaged to the turnaround track. The turnaround mechanism may further include a track exchange mechanism having a track exchanger for transitioning the at least one roller of each of the plurality of pallets between the passenger and the return sides, each of the plurality of pallets generally maintaining its orientation during the transitioning.
US09499375B2 Elevator with detachable drive unit
An elevator including one or more hoisting members that are continuous in the vertical direction, a load-receiving part suspended on the hoisting member, and also a driving member engaging with the hoisting member for moving the load-receiving part. The driving member engaging with the hoisting member is configured to be driven with a detachable drive unit.
US09499372B1 System and apparatus for storage, transport and management of electrical cord and cable
An apparatus the storage of electrical cord, including an elongated bag defining an exterior surface and an interior storage volume with a circular opening at one end, a cord channel around the opening, a closure cord extending through the channel, a cord lock connected to the closure cord, a slot formed through the exterior surface, an elongated apron positioned to cover the slot and connected to the exterior surface, defines opposing side apertures for communication with the slot, a pocket formed on the apron, at least one transverse strap extending across the apron for securing cord extended between the strap and the apron, and a carry strap with the first end connected to the bag and the second end connected to the bag opposite the apron. A male end of a length of electrical cord may be fed into the bag through the slot and out a respective side aperture. The remaining length of electrical cord may be fed into the bag for storage.
US09499369B2 Continuous feed material dispenser with adjustable brake
A braking assembly used in a dispenser that dispenses a continuous supply of material such as paper. The braking assembly includes a support structure. A first fixed gear is rotatably connected to the support structure. A movable chassis is also connected to the support structure. A second movable gear is held by the chassis and moves with the chassis. Teeth of the first gear and teeth of the second gear intermesh with each other and allow the paper to pass therethrough. The chassis maintains the teeth of the first and second gears in contact with each other while enabling a distance between gears to be adjustable. The assembly further includes a braking mechanism that varies an amount of force required to rotate the gears.
US09499365B2 Sheet feeding device and image forming apparatus
A sheet feeding device includes a sheet storage unit, a driving unit, a first detection unit, a second detection unit, and a control unit. The sheet storage unit includes a tray on which a sheet bundle including a plurality of sheets is to be stacked. The driving unit lifts up the tray. The first detection unit detects, at a predetermined position, a top surface of the sheet bundle stacked on the tray and lifted up. The second detection unit detects whether a sheet is stacked on the tray. The control unit controls, while the first detection unit has not detected the top surface of the sheet bundle, the driving unit to lift up the tray at a first speed until the second detection unit detects the sheet, and to lift up the tray at a second speed lower than the first speed after the second detection unit detects the sheet.
US09499361B2 Belt conveyor unit and image forming apparatus including same
A belt conveyor unit includes a plurality of rollers around which a belt is entrained, including a first roller, a second roller disposed opposite the first roller via the belt, and a third roller other than the first roller and the second roller, and a belt alignment device including a shaft moving device to tilt a rotary shaft of the third roller upon receiving a moving force of the belt moving in a width direction of the belt in an axial direction of the rotary shaft to adjust displacement of the belt. The shaft moving device includes an axial-direction displacement member including a slanted surface that moves to a first side in the width direction of the belt along the rotary shaft upon receiving the moving force of the belt, and a fixation member to contact the slanted surface from the first side in the width direction of the belt.
US09499356B2 Horizontal support system
A system supports an outlet, within a storage silo, of a pneumatic conveyor. The outlet comprises a horizontal section, a vertical section, and an elbow interconnecting the sections. The system comprises a vertical support for suspending and centering the outlet, and a horizontal support for selectively supporting the outlet upon the silo floor. The horizontal support has clamp assemblies mounted on the horizontal section, and sets of removable support legs respectively attachable to the clamp assemblies. The horizontal support also has elbow clamp assemblies adjacent the elbow, and an elbow brace and a subframe each interconnecting the elbow clamp assemblies. Each of the support legs has a locking pin for locking that leg in a deployed position, and a storing hole for placing that leg in a stored position. The system further comprises a deflector, and sets of stanchions therefor respectively attached to the clamp assemblies of the horizontal support.
US09499355B2 Pedestal for supporting an adhesive melter and related systems and methods
A pedestal for use with an adhesive melter adapted for melting adhesive particulates includes a support structure, a hopper, and a flow tube. The support structure has an upper portion adapted to support the adhesive melter. The hopper is connected to the support structure and positioned generally below the upper portion of the support structure. In addition, the hopper has an opening adapted for receiving adhesive particulates for storage therein. The flow tube has a first end portion and a second end portion. The first end portion is fluidly connected to the hopper, and the second end portion is fluidly connected to the adhesive melter. Furthermore, the flow tube is configured for moving adhesive particulates from the hopper to the adhesive melter via an air pressure differential created between the first and second end portions of the flow tube.
US09499353B2 Container conveyor device
A conveyor device having a rotor and container carriers that suspend containers around the rotor includes a container support to support the sides of the suspended containers. The container support has an outer container guide with a height-adjustable outer container support surface that defines a tapered surface surrounding a machine axis about which the rotor rotates. The outer container support surface supports the containers on a radially outward portion of their surface and an inner container support surface supports the containers on a radially inward position of their lateral surface. The two support surfaces define a receptacle that receives the container's base. The receptacles width decreases as a function of distance from the container carriers. The inner container support surface is height-adjustable for adapting the container support device to different container base diameters.
US09499350B2 Method for operating a conveyor installation
A method operates a conveyor installation having a belt and at least one drive drum for driving the belt. The torque acting on the drive drum is controlled, in order to alter the speed of the belt, within a time window that is defined by a first rotational speed of the drive drum and a second rotational speed of the drive drum.
US09499343B2 Conveying system, and use of a chamber extending inwardly with respect to a plastic module in a conveying system
The invention relates to a conveying system. The conveying system comprises a conveying track, an endless conveyor mat for conveying products in a conveying direction, a drive for driving the conveyor mat, and a return guide provided at the conveying track for guiding the conveyor mat upon circulation. The return guide extends substantially transversely to the conveying direction. The conveyor mat comprises a number of plastic modules, which are provided at their bottom side with a track guide surface, while at least a part of the plastic modules at the location of the respective track guide surface comprise at least one chamber extending inwardly with respect to the module for being in a contact with the return guide during circulation of the module around the return guide. The chamber is formed such that the contact upon circulation consists of a first line contact and a second line contact.
US09499338B2 Automated bot transfer arm drive system
An autonomous transport vehicle including a transfer arm including at least one finger and a movable finger support member, at least one sensor configured to detect movement of the at least one finger, the at least one sensor having a registration member and a detection member where one of the registration member and detection member is mounted to each of the at least one finger so as to be movable with a respective one of the at least one finger and the other one of the registration member and detection member is stationary relative to the at least one finger, and a controller in communication with the at least one sensor, the controller being configured to determine a position of the at least one finger along the second direction based on a proximity of the registration member relative to the detection member.
US09499336B2 Fully autonomous lashing platform
Lashing platform with a mount for mounting a container set down on the lashing platform, wherein the mount is spring-mounted in the vertical direction and is connected via a first line to a gas storage unit for storing the energy released when setting the container down on the mount of the lashing platform, and the gas storage unit is connected via a second line to screwing devices which are supplied with energy from the gas storage unit and are intended for removing twist-locks from and inserting them into the container, characterized by a third line connected to the first line and/or to the gas storage unit, and a generator for producing electrical energy that is driven by the volumetric flow conveyed in the third line.
US09499333B2 Capsule, beverage production machine and system for the preparation of a nutritional product
The present invention presents a capsule 1 having an inlet face C, which is formed by a circular section 2a and a bulge section 2b extending from the circular section 2a giving the inlet face C a not symmetric in rotation. The capsule 1 further has an optically readable code 3 on a side wall 4 of a cup-shaped body of the capsule 1 opposite the bulge section 2b. The present invention further presents a beverage production machine with a capsule holder 13 for holding a capsule 1 in such a way in the beverage production machine 10, that the optically readable code can be read by a code reader 24. Liquid can be supplied to the capsule to produce a nutritional product. The present invention provides means to prevent the optically readable code 3 and the code reader 24, respectively, from being contaminated with liquid, vapor, dirt or the like. An automatic detection of the capsule type, and a corresponding automatic setting of preparation parameters by the beverage production machine 1 becomes possible, and is more reliable than state of the art solutions.
US09499331B2 Reinforced resealable inner package for container
The present invention relates to a container (100) for consumer goods. The container (100) comprises an outer housing, including a box (102) and a lid (104). The container also comprises an inner package (106) of consumer goods within the outer housing having an access opening through which consumer goods can be removed, an inner frame (112) within the inner package, and an adhesive label (108) covering the access opening of the inner package and extending beyond the periphery of the access opening of the inner package, the adhesive label (108) being at least partially releasably affixed to the outer surface of the inner package (106) by a releasable adhesive. At least one portion of the inner surface of the inner package (106) is permanently affixed, using affixing means, to a corresponding portion of the outer surface of the inner frame (112).
US09499328B2 Methods and apparatus for dispensing solid articles
A dispensing apparatus for dispensing articles includes a housing and a drive system. The housing defines a hopper chamber to hold the articles, a dispensing outlet, and a dispensing path between the hopper chamber and the dispensing outlet. The drive system includes a belt and a belt actuator operable to drive the belt. The dispensing apparatus is configured such that articles disposed in the hopper chamber are directed onto the belt and the belt, when driven by the belt actuator, conveys the articles received from the hopper chamber in a dispensing direction along the dispensing path toward the dispensing outlet to be dispensed.
US09499325B2 Packing bag with cushoning function
A packing bag with a cushioning function includes: a first cushioning air cylinder portion, constituted by air cylinders; a second cushioning air cylinder portion, constituted by air cylinders, and coupled to the first cushioning air cylinder portion to form an accepting space; and a binding belt, coupled to the first cushioning air cylinder portion and/or the second cushioning air cylinder portion, and used for sealing an opening of the accepting space. The first cushioning air cylinder portion and second air cylinder portion constituted by the air cylinders can perform the cushioning protection of an object effectively, solving the problem of the shock-absorption capability insufficiency of the conventional small air sacs, solving the problem of the conventional small air sacs being insufficient in shock-absorption capability. In addition, the binding belt not only allows a label to be attached thereon, but also avoids the air cylinder being pierced through.
US09499323B2 Packaged article arrangement
A packaged article arrangement is disclosed. The arrangement includes an article including an article energy source and an article transmitter unit for transmitting electromagnetic radiation; and a package that at least partly envelopes the article. The package includes an electronic circuit that includes a package receiver unit arranged for receiving the electromagnetic radiation transmitted by the article transmitter unit, the electronic circuit being arranged for using the received electromagnetic radiation as sole or additional power supply.
US09499322B2 Flexible package
A flexible package including a package body including a first side-surface film and a second side-surface film sealed in a peripheral portion such that a storage portion is formed in the package body. The package body has sealed portions formed in side edge portions such that a non-sealed portion is formed in at least one of the sealed portions. The non-sealed portion has a gas injection portion containing a gas which has a specific heat at constant volume of 0.67 kJ/kg·deg or higher at 0° C. and 1 atm. The gas injection portion has a diameter in a range of from 3 mm to 50 mm and is formed such that a repelling force is in a range of from 4 N to 30 N at 23° C. and 1 atm when an entire gas injection portion is nipped from both sides of the first and second side-surface films and squeezed until a nipped gas injection portion has a width equal to a half of the diameter of the gas injection portion.
US09499319B2 Method of forming a carton with article protection feature
A method of forming a carton. The method includes obtaining a blank having at least one panel and at least one article protection flap foldably connected to the at least one panel. The method includes positioning the at least one panel to at least partially form an interior space of the carton, loading at least one article in the interior space, and folding the at least one article protection flap relative to the at least one panel after the loading the at least one article. The folding includes moving the article protection flap from a first position that is substantially parallel to the at least one panel to a second position wherein the article protection flap is folded relative to the at least one panel.
US09499316B2 Hydrogen encapsulating cap for beverage container
[Problems to be Solved the Invention]To provide a hydrogen encapsulating cap for a beverage container, which can improve water-tightness, while preventing increase in the cost for producing a body of the cap. [Means for Solving the Problem]There is provided a hydrogen encapsulating cap 3 including a cylindrical cap body 10 formed with a female screw portion 12 for mating with a male screw portion 1b of a beverage container mouth 1a, a hydrogen encapsulating bag 30 accommodated in the cylindrical cap body 10, a press member 20 for rupturing the hydrogen encapsulating bag 30 by pressing from the above and a downward movement regulating plate 13 disposed in the lower portion of the cylindrical cap body 10 and above the female screw portion 12, and the downward movement regulating plate 13 is formed with a water-tight piece contacting the upper end surface of the beverage container mouth 1a and a passage opening through which hydrogen discharged from the hydrogen encapsulating bag 30 can pass.
US09499314B2 Flexible bag having a spout and a fitment assembly
A spout and fitment assembly for a flexible bag. The spout comprises a base flange, a cylindrical upstand and a fitment coupling. The base flange is configured to be coupled to a flexible bag. The cylindrical upstand extends from the base flange. The cylindrical upstand defines a passageway therealong which is placeable in fluid communication with the flexible bag. The fitment coupling extends from the cylindrical upstand between the proximal end and the distal end thereof. The fitment assembly comprises a fitment body and a hose. The hose is coupled to the hose connection portion. The connector portion is sealingly engaged with the fitment coupling so as to place the inner bore in fluid communication with the passageway of the cylindrical upstand.
US09499308B2 Gusset grip containers and methods for the manufacture thereof
Containers and methods for their manufacture are provided. Containers include first and second panels connected at first and second edges, a bottom panel connecting the first and second panels at a third edge, a panel area defined by a seal extending from the first edge and having a first aperture at a first corner of the container, and a pour feature disposed at least partially at a second corner diagonally opposite the first corner, wherein the bottom panel or the first edge comprises a gusset. Methods include forming such container and forming at least one aperture in the panel area.
US09499302B2 Preform container having a coiled handle attached at two attachment points
A method of forming a container from bi-axially orientable plastics material and having an integral handle with the steps of forming a preform having a neck portion and an expandable portion below the neck portion, with the neck portion including a locating ring above the expandable portion and a handle molded to the non expandable at one end and molded to the expandle portion at the other end. Where the molded-in handle is the approximate length of the handle of the finished container. The unblown preform of orientable plastics is inserted into a blow molder and thereafter stretched by a stretch rod. During the stretch process the handle on the preform unbends rather than stretching to form the approximate shape of the handle in the finished container. The blow mold then closes on the stretched preform thus capturing the handle. Blow gas is then injected into the interior.
US09499291B2 Hold-open device and package having same
A device for selectively retaining a package opening in a gaping configuration and a package including the device applied to a package body. The device includes a circumferential strip with side seams formed as hinges. One or more tabs extend in a first axial direction from an upper edge of the circumferential strip at the side seams. Each tab is coupled to the circumferential strip with a hinge. The tabs are pivotable about the hinges in opposite directions away from the opening axis to respective folded-out positions, which inhibits the device from folding at the side seams and retains a gaping open configuration of the device and package.
US09499290B2 Stationary bubble reactors
Reactors that allow mixing and gasification by converting the entire floor of the reactor vessel to a sparge filter is described.
US09499288B2 Method and apparatus for vacuum packing resealable bags
The present invention discloses a method and apparatus for closing a resealable vacuum bag while the vacuum bag is still inside the vacuum chamber of a heat-sealing vacuum packing machine. The resealable bag may be automatically closed, at least temporally, by either (1) the compressive forces that vacuum packing machines exert against the sides of vacuum bags, or (2) an autonomous, vacuum-activated device that closes the open section of the vacuum bag's sealing strip. Finally, the cost of the resealable vacuum bag may be minimized by eliminating the air valve that is imbedded in the sides of conventional resealable vacuum bags, but which is superfluous for the present invention.
US09499287B2 Tray gripper head
A method and device for unstacking a stack of trays, each tray having pockets and edge portions. A holder frame above the stack has suction heads which engage the eggs of the uppermost tray of the stack. A carrier unit above the holder frame has oppositely opposed grippers which engage sides of the uppermost tray. The holder frame is connected to the carrier unit by one or more spacer rods which are freely moveable in a channel in the carrier unit so as to permit three degrees of movement relative thereto. The carrier unit may also be moveably suspended in a second carrier unit above it. Support rods may extend downwardly from the carrier unit to engage the tray.
US09499285B2 Three dimensional imaging arrangement
A spacecraft arrangement having sensors for providing the three dimensional imaging of space object to be imaged and having a plurality of spaced apart nodes defining an open imaging area therebetween through which imaging area the space object to be imaged passes.
US09499281B2 Landing arresting system for vertical take-off and landing (VTOL) aerial vehicles, landing and take-off platform for VTOL aerial vehicles and VTOL locking member for aerial vehicles
A landing arresting system for vertical take-off and landing aerial vehicles. A landing and take-off platform and at least one vertical take-off and landing locking member have a projecting portion arranged at a lower portion of the vehicle. The landing and take-off platform includes a plurality of individually displaceable rolls, arranged substantially in a horizontal direction, and moveable back and forth, such that the projecting portion of the locking member can be entered, retained and released between two adjacent rolls. A landing and take-off platform for vertical take-off and landing aerial vehicles and a vertical take-off and landing locking member for aerial vehicles.
US09499279B2 System and method for displaying runway approach information
A system and method are disclosed for indicating to an aircrew of an aircraft an unstable approach to a desired landing. When the energy state of the aircraft exceeds a threshold, a suggested airspeed in consideration of the energy state is displayed. Additionally, a landing spots on a displayed runway are shown indicating where the aircraft would land in view of the energy state and where the aircraft is recommended to land in view of the current aircraft type and weight. A text message may also be displayed that conveys the ability of the aircraft to land.
US09499277B2 Aircraft comprising a distributed electric power unit with free wheels
An aircraft comprising rotors and/or propellers rotated by a shaft and including a power unit. The distributed electric power unit is formed by stacked electric power elements, each conferring, on the shaft, a fraction of the total power necessary; the distributed electric power unit is in direct engagement with the shaft, with no movement transmission mechanism inserted between the unit and the shaft; each electric power element is directly connected to the rotation shaft and comprises a fixed stator, a moving rotor and a mechanical or electromagnetic free wheel in direct engagement with the shaft, said moving rotor co-operating with the free wheel to be coupled to the rotation shaft during normal operation of the electric power unit and to be disconnected from the shaft in the event of the failure of the electric element.
US09499269B2 Overhead equipment stowage pod for an aircraft interior
An overhead equipment stowage pod comprises a base having a structural material surrounding a central opening. The central opening is open on top and bottom, and the base is fastened to a support structure proximate a ceiling. A replaceable stowage bin is at least partially inserted through the base into the ceiling, and a closeable door is suspended below the stowage bin.
US09499268B2 Near belly-tangent pod system for an aircraft
A pod system for an aircraft is disclosed. Embodiments provide an external, near belly-tangent modular plug-and-play pod system that includes a scalable set of left-side bays which are connected to a scalable set of right-side bays via a central compartment positioned on a bottom external surface of the aircraft's fuselage. The bays accommodate removable slide trays which have various equipment (for example, communications, intelligence, surveillance, and reconnaissance equipment) mounted thereon. The bays and slide trays combination allow for quick removal, insertion, and connection of the various mounted equipment to IP-based connectivity, power, and foundation signals from the aircraft. In an embodiment, the left-side bays, right-side bays, and central compartment each have a planar bottom surface which are substantially equiplanar so that inserted and connected mounted equipment extending downward and externally from the bays from the planar bottom surface have 360 degree unobstructed views.
US09499266B1 Five-wing aircraft to permit smooth transitions between vertical and horizontal flight
A five-wing aircraft transitions smoothly between vertical and horizontal flight modes, and enhances pitch neutrality of the aircraft when in flight at all speeds to improve flight efficiency. The aircraft includes a fuselage, a fixed wing assembly coupled to the fuselage and having a front fixed wing and a rear fixed wing, the front fixed wing coupled to the front portion of the fuselage and the rear fixed wing coupled to the rear portion of the fuselage, the front fixed wing and rear fixed wing being connected together by winglets, a tilt-wing pivotably mounted to the central portion of the fuselage, and a pair of rotary wings coupled to the tilt-wing. The tilt-wing pivotably adjusts to permit the aircraft to transition smoothly between vertical and horizontal flight. The rotary wings generate thrust or lift depending on the orientation of the tilt-wing.
US09499265B2 Unmanned aerial vehicle landing interface
The present disclosure is directed toward systems and methods for autonomously landing an unmanned aerial vehicle (UAV). In particular, systems and methods described herein enable a UAV to land within and interface with a UAV ground station (UAVGS). In particular, one or more embodiments described herein include systems and methods that enable a UAV to conveniently interface with and land within a UAV ground station (UAVGS). For example, one or more embodiments include a UAV that includes a landing base and landing frame that interfaces with a landing housing of a UAVGS.
US09499262B2 Composite flexure for tiltrotor rotor system
A composite flexure that secures a rotor blade to a gimbaled yoke in a tiltrotor rotor system. The composite flexure includes a composite flexure member, a first end, and a second end. The first end of the composite flexure couples the composite flexure to the gimbaled yoke, and the second end of the composite flexure couples the composite flexure to the rotor blade. The composite flexure is twisted when the composite flexure is not subject to torsional loads in order to accommodate various forces imparted on the rotor system.
US09499261B2 Friction-based shimmy damper for landing gear
A system for damping vibration and/or shimmy of a landing gear system is disclosed. The system is a friction-based damping system that utilizes a friction pad and friction wedge to dampen vibration and/or shimmy. The friction pad may be coupled to an apex pin that is used to couple a first torque link and a second torque link together. The friction wedge may be a made of a wearable and/or consumable material.
US09499260B2 Aircraft landing gear wheel with integral gear drive
An aircraft landing gear wheel is disclosed. A main body includes a hub portion with a gear end and an attachment end. A driven gear portion includes a first annular rail and a second annular rail, the driven gear portion being integrally and drivingly connected with the hub portion at the gear end. Rollers are rotatingly connected between roller apertures of the first annular rail and the second annular rail. Bearings rotatingly support portions of the rollers within the roller apertures.
US09499258B2 Device for concomitant opening or closing of two flaps of a landing gear door
A device for concomitant opening or closing of two flaps of a door of an aircraft retractable landing gear. The device comprises a single actuating means for the opening or the closing of the two flaps under the effect of its extension or of its retraction. The actuating means comprises a first end linked to the structure of the aircraft, and a movable part. The device comprises a swinging arm comprising a first end linked by a pivot to the structure, and a second end linked to the movable part of the actuating means by a link having a degree of rotational freedom about an axis parallel to the axis of the pivot. The second end of the swinging arm is furthermore respectively linked to a first tie rod linked to a first of the two flaps, and to a second tie rod linked to a second of the two flaps.
US09499257B2 Weight reducing landing gear features
Aircraft landing gear is provided comprising a trunnion arm having a centering portion and a first stress relieving portion and an outer cylinder coupled to the trunnion arm is disclosed. The first stress relieving portion may relieve stress spreading from the centering portion to the outer cylinder. In addition, the first stress relieving portion may be disposed adjacent the centering portion, and may relieve stress spreading from the centering portion to at least one trunnion arm portion. In various embodiments, the aircraft landing gear disclosed herein may further comprise a cross bolt portion formed in a portion of the trunnion arm and a second stress relieving portion disposed adjacent the cross bolt portion. The second stress relieving portion may relieve stress spreading from the cross bolt portion to at least one trunnion arm portion.
US09499255B2 Wing tip device attachment apparatus and method
A winglet (114) is attached to a wing tip (112) by a main beam (132) which extends into the wing tip (112) and is attached to the rear spar (118). A canted spar (134) also extends to be attached proximate the forward spar (116).
US09499253B1 Composite rotor blade for a reaction drive rotorcraft
Apparatus and methods are disclosed for designing and manufacturing a composite structure, such as a composite rotor blade spar or composite rotor blade. A first mold may define a first mold surface and a second mold may include a rigid layer and a heated layer secured to the rigid layer and defining a second mold surface. A plurality of heating elements embedded in the second mold may be activated according to different temperature progressions to cure portions of the uncured composite rotor blade positioned coextensive therewith. In some embodiments, the second mold defines a root portion and first and second branch portions. A shear web may be placed between the branch portions during curing. The blade spar may define a complete airfoil contour or have fairings secured thereto having lines extending therethrough to a tip jet. A tip jet mounting structure and blade root attachment apparatus are also disclosed.
US09499252B2 Wing fold controller
Illustrative embodiments may provide for an apparatus and method of controlling the folding of a wing. The apparatus may include a sensor, an actuator, and a wing fold controller. The method may include receiving a status of at least one of an aircraft and a wing fold system of the aircraft by the wing fold controller of the wing fold system. The method may also include receiving an automated command by the wing fold controller in response to receiving the status. The method may also include operating the wing fold system by the wing fold controller based on the automated command and the status. The method may also include transitioning a wingtip of a wing of the aircraft to one of a flight position and an on-ground position by an actuator of the wing fold system in response to commands from the wing fold controller.
US09499247B1 Marine outboard engine having a tilt/trim and steering bracket assembly
A marine outboard engine for a watercraft has a stern bracket for mounting the marine outboard engine to the watercraft, a swivel bracket pivotally connected to the stern bracket about a generally horizontal tilt/trim axis, and a drive unit pivotally connected to the swivel bracket about a steering axis. The steering axis is generally perpendicular to the tilt/trim axis. A hydraulic actuator is operatively connected to the stern bracket and the swivel bracket for pivoting the swivel bracket and the drive unit relative to the stern bracket about the tilt/trim axis. A pump is mounted to the swivel bracket. The pump is pivotable about the tilt/trim axis together with the swivel bracket. The pump is fluidly connected to the hydraulic actuator to supply hydraulic fluid to the hydraulic actuator.
US09499244B2 Inflation device with means for preventing the removal of the pressurized gas container
An inflation device 10 for an inflatable article comprises a housing 11 for supporting a container 15 of pressurized fluid and for supporting piercing means which is displaceable from a retracted position to penetrate the container and allow release of pressurized fluid, said container being contained within a protected casing 20 which is secured non-releasably to the housing thereby to prevent removal of the pressurized container.
US09499242B2 Wakeboat hull control systems and methods
Wakeboat hull control systems and methods are provided to monitor the orientation of the wakeboat hull in the surrounding water, and to automatically control wakeboat ballast components to achieve or maintain desired hull orientations. Systems and methods are provided to measure, store, and recall hull orientation. Systems and methods are also provided to enable automated action to improve the safety, automation, performance, convenience, and marketing advantage of wakeboat ballast systems.
US09499240B2 Floating marine structure
The invention provides a sub-structure (2) comprising at least one leg (4) having first buoyancy means (4a) arranged in a lower part of the at least one leg to provide a first buoyancy, and a float element (3) having second buoyancy means to provide a second buoyancy, wherein the sub-structure and the float element are constructed to allow relative wave induced motion with respect to each other in a substantially vertical direction wherein the leg is movable from a pre-installation position to an installation position by a substantially downwards movement of the leg with respect to the float element, and wherein during at least a second part of the downwards movement of the leg towards the installation position and/or in the installation position the first buoyancy means are substantially located below a wave zone to substantially decrease heave action on the first buoyancy means.
US09499234B2 Bicycle component control apparatus
A bicycle component control apparatus is configured to control at least one bicycle component. The bicycle component control apparatus basically comprises a user operating device, an electric actuating unit and a hydraulic unit. The electric actuating unit is controlled in response to operation of the user operating device. The hydraulic unit is fluidly connected to the at least one bicycle component so as to fluidly control the at least one bicycle component in response to actuation of the electric actuating unit.
US09499233B2 Mechanism for transmitting a rotary movement with variable transmission ratio
A control mechanism (800) for setting a transmission ratio between a traction means (812), in particular chain, and a wheel set that is rotatable about a wheel axle and includes two or more wheel blades (810, 820, 830), in particular sprocket blades, adjusts the wheel rim sectors relative to a fixed plane of the traction means in a direction transverse to the plane of alignment. At least one of the wheel blades is composed of a plurality of independently adjustable wheel rim sectors (802, 803). By means of a control component (807) mounted decoupled from a rotary movement of the wheel set, a plurality of co-rotating thrust elements (804, 805) are each displaced via rotation-free couplings between a first and a second position at least in the axial direction, wherein each of the wheel rim sectors is connected in a rotationally fixed manner to a respectively associated thrust element. The first position of a thrust element corresponds to the position of the associated wheel rim sector outside the plane of alignment, whereas a thrust element located in the second position exerts on the respective wheel rim sector, at least as long the latter is outside the plane of the traction means, a force for displacing the respective wheel rim sector into the plane of alignment, thus shifting the same into the plane.
US09499229B2 Bicycle for transporting a child with increased stability
The aim of the invention is to improve the stability of bicycles fitted with at least one seat for transporting children, by re-centering and lowering the centre of gravity of the child via a specific frame structure, optionally in combination with a choice of reduced wheel diameters and/or an increase in the spacing of the pedals. The location for the feet (31) of the child is inside the supporting structure (9, 10′) of the bicycle linking the seat tube (4′) to the rear wheel axle (14).
US09499228B2 Self-balancing vehicle frame
A self-balancing vehicle frame includes two side frame units and a bearing unit interconnecting the side frame units such that each of the side frame units can tilt independently against the other of the side frame units. Each of side frames is mounted with a wheel, a driver, and a self-balancing electric system integrated with a pedal and handle. Through operation of hands and feet, each of the side frame units is operable to tilt the corresponding components forwardly and rearwardly. As such, a user can operate the vehicle using hands and/or feet to control travelling and turning of the vehicle.
US09499221B2 Integrated duct step garnish assembly
An integrated duct step garnish assembly for a vehicle includes a deck member defining a stepping area on an upper side thereof and an underside member secured to an underside of the deck member for defining an air duct between the underside member and the deck member. The air duct extends along a longitudinal length of the deck member and the underside member for delivering conditioned airflow to a rear of the vehicle.
US09499216B2 Floor load structure for vehicle body to frame mount
A vehicle floor structure includes a cross member having a substantially constant cross section shape. A spacing member is disposed beneath the cross member for securing to a chassis frame. The spacing member is positioned relative to the cross member to define an enclosed cavity between the spacing member and the cross member. The floor structure also includes a first collar affixed within the enclosed cavity. A fastener extends through the spacing member and the cross member, and compresses the first collar when the floor structure is secured to the chassis frame.
US09499206B2 Vehicle rear structure
In a vehicle to which a vehicle rear structure is applied, a rear roof-side inner of a roof-side inner is joined to a front roof-side inner of the roof-side inner at locations of first joins, of an overlap flange. Configuration is thereby such that strength is high at the overlap flange of the roof-side inner. Moreover, the rear roof-side inner is joined to both the front roof-side inner and the upper support at the location of a second join of the overlap flange. This enables upthrust load from a rear suspension to be effectively transmitted to the overlap flange, and distributed to the front roof-side inner and the rear roof-side inner. This enables rigidity of the roof-side inner to be secured.
US09499205B1 Hybrid vehicle packaging system
A vehicle includes a fuel tank, a battery, a first exoskeleton, and a second exoskeleton. The fuel tank and the battery straddle a driveline and are each disposed below a seating area. The first exoskeleton has a first pair of rails secured to each other by a first cross member. The second exoskeleton has a second pair of rails secured to each other by a second cross member. The first and second exoskeletons surround the fuel tank and battery, respectively, and are configured to absorb energy during an impact to protect the fuel tank and battery.
US09499204B1 Suspension system and ride-on grounds maintenance vehicle incorporating same
A suspension system for use with a grounds maintenance vehicle such as a ride-on lawn mower. In one embodiment, the suspension system provide at least a first suspension apparatus positioned between a chassis of the mower and an operator support platform. The first suspension apparatus may include one or more suspension units that may be quickly reconfigured to provide variable suspension characteristics. The system may also include a second suspension apparatus longitudinally spaced-apart from the first suspension apparatus. A pivot member may be provided to assist in reducing or eliminating all but certain degrees of freedom of the platform relative to the chassis.
US09499202B2 Steering system and method for autonomous vehicles
A steering system for an autonomous vehicle includes a steering mechanism having a pinion gear and a rack, the steering mechanism being configured to translate rotation of the pinion gear into movement of the rack which is configured to affect the position of a steer tire of the autonomous vehicle, thereby affecting the lateral position of the autonomous vehicle; a steering wheel which provides a mechanical input to the pinion gear from an operator of the autonomous vehicle; a steering actuator which rotates to apply torque to the steering mechanism, thereby inducing movement of the rack which affects the position of the steer tire of the autonomous vehicle; and a variable coupling member operatively between the steering actuator and the steering mechanism which is configured to vary the torque that can be transmitted from the steering actuator to the steering mechanism.
US09499198B2 Steering system for a vehicle and steering method for a vehicle
A steering system for a vehicle includes at least two wheels configured to be steered independently of each another. A steering setpoint generator is configured to steer the at least two wheels according to a steering program. An operating element is configured to rotate the vehicle during travel about a center of rotation which moves with a principal movement vector. The steering program is configured so that a direction of the principal movement vector of the center of rotation can be changed with the steering setpoint generator.
US09499197B2 System and method for vehicle steering control
A method for steering control of a vehicle having an actuator which turns steered wheels of the vehicle. The steering control method includes obtaining a location of a target point at a look-ahead distance away from the vehicle based on a maneuver the vehicle is performing, predicting a forward location of the vehicle at the look-ahead distance away from the vehicle, determining a distance between the location of the target point and the forward location, computing a normalized error by dividing the distance with the look-ahead distance, and determining a steering control command based on an integration of the normalized error. The actuator then turns the steered wheels of the vehicle according to the steering control command so as to steer the vehicle to perform various maneuvers.
US09499194B2 Electric power steering system
In a speed reducer of an electric power steering system, a first bearing supports a first end portion of a worm so that the first end portion is movable in an axial direction. Elastic members elastically support the worm in the axial direction. A second bearing supports a second end portion of the worm. An urging member oscillates and urges the worm. The sum of first frictional resistance in the axial direction between an inner ring of the first bearing and the worm and second frictional resistance in the axial direction between the urging member and an outer circumference of an outer ring of the second bearing is less than engagement frictional resistance in the axial direction of the worm.
US09499190B2 Adjustable steering column assembly having self-de-lashing power-rake mechanism
A self-de-lashing power-rake mechanism of an adjustable steering column assembly of a vehicle is provided. The power-rake mechanism includes a jacket, rake bracket coupled to the jacket, and rake bolt extending through the jacket and bracket. At least one pivot bushing is disposed between the jacket and bracket and configured to receive and radially constrict around the bolt. A fastener is configured to be positioned onto the bolt, tightened, and seated on the bracket. The bolt is forced through the fastener, bracket, bushing, and jacket. The bolt is seated on the bracket as the fastener is tightened and draws the bolt, fastener, bracket, bushing, and jacket together as the fastener is being seated on the bracket, thereby de-lashing respective interfaces defined between and among the bolt, fastener, bracket, bushing, and jacket. A steering column assembly including the mechanism is also provided.
US09499186B1 Pallet transfer apparatus with handle pulling type folding structure
A pallet transfer apparatus with a handle pulling type folding structure includes a moving body unit which includes a pair of deformed fitting type horizontal support units which are arranged parallel at regular intervals and is configured to move by loading a pallet on a pair of the horizontal support units; a height adjusting body unit which includes a pair of vertical support units which are connected in a vertical direction from each of a pair of the horizontal support units, wherein the heights of the vertical support units can be adjusted; and a folding adjusting unit which includes a horizontal bar-shaped handle connected to the top of each of a pair of the vertical support units.
US09499185B2 Wayside guideway vehicle detection and switch deadlocking system with a multimodal guideway vehicle sensor
A multimodal guideway vehicle sensor includes a passive sensor, an active sensor and an unique identification (ID) sensor. The passive sensor is configured to receive and detect a first electromagnetic radiation from a guideway vehicle. The active sensor configured to transmit a second electromagnetic radiation and receive and detect the second electromagnetic radiation reflected from the guideway vehicle. The ID sensor that detects an ID associated with the guideway vehicle. The multimodal guideway vehicle sensor also includes a data fusion center that combines signals from the passive sensor, the active sensor and the ID sensor to produce guideway vehicle information about the guideway vehicle.
US09499184B2 Method of determining a position of a vehicle on a guideway
A method of determining a position of a vehicle on a guideway includes detecting a position of the vehicle relative to a first reflective positioning element along the guideway. The method also includes detecting a unique identification code of a transponder along the guideway, wherein the transponder is located a first known distance along the guideway from the first reflective positioning element. The method further includes determining the position of the vehicle, using a position determining system, based on a modulated reflection signal received from the transponder, a first non-modulated reflection signal received from the first reflective positioning element, and the first known distance.
US09499182B2 Composite brake cylinder for a rail vehicle
A brake cylinder having a filament wound composite pressure cylinder and a composite plastic non-pressure head. The pressure cylinder and non-pressure head are secured together by a pair of mating flanges and a V-shaped band securely attached over the flanges. The band has a gap that is easily adjustable to position the gap at the lowest point and be in alignment with a series of radially extending grooves in the flange of the non-pressure head, thereby ensuring proper drainage. The non-pressure head may include an integrally formed opening with a bearing surface for a piston rod, a seat for a piston return spring, a scraper for a piston rod, and a series of internal ribs that provide for structural support and act as stop against a piston overtravel.
US09499181B2 Zipline braking system
A zipline braking system comprising a zipline cable and a destination supporting member; a rider carrier coupled to the zipline cable for movement towards the destination supporting member, such movement generating kinetic energy; a damper having a posterior end and an anterior end and connected to the destination supporting member at the posterior end; a tension line; a stopping member coupled to the zipline cable and the tension line; and the tension line for transferring the kinetic energy to the damper upon the rider carrier engaging the stopping member in movement to the destination supporting member.
US09499177B2 System and method of modifying the friction of railroad tracks
A railroad friction-modification system for applying a friction modifier to a section of railroad track, the system comprising an external storage tank for storing the friction modifier, a railroad friction-modification assembly for applying the friction modifier, a tube for connecting the external storage tank to the railroad friction-modification assembly, and a mounting assembly for securing the railroad friction-modification assembly to the rail. The railroad friction-modification assembly includes an expandable membrane for storing the friction modifier, an inlet valve for receiving the friction modifier from the external storage tank, a housing for securely containing the expandable membrane, at least one outlet valve for expelling the friction modifier from the expandable membrane upon the application of a force, and a nozzle for directing the expelled friction modifier onto the section of railroad track. The force is applied by the wheel of a railroad car, such that the railroad friction-modification assembly pumps the friction modifier in a peristaltic action.
US09499174B2 Method and apparatus for isolating a fault-active controller in a controller area network
A method for monitoring communications among a plurality of controllers signally linked to a communication bus of a controller area network includes monitoring bus communications including determining bus error counts for a plurality of execution cycles. When a bus error count associated with message transmission from one of the controllers exceeds a predetermined threshold, the one of the controllers is prohibited from communicating on the communications bus for a predetermined period of time and is included in a subset of candidate fault-active controllers. Any of the plurality of controllers included within the subset of candidate fault-active controllers that successfully transmits a message is removed from the subset of candidate fault-active controllers. A fault-active controller is isolated based upon the subset of candidate fault-active controllers and the bus error counts.
US09499173B2 Vehicle comfort system for using and/or controlling vehicle functions with the assistance of a mobile device
Vehicle with a comfort system having: a vehicle controller device, via which different vehicle systems and/or vehicle functions can be controlled; at least one vehicle communication device for exchanging data via wireless communication; a plurality of identification modules arranged in the vehicle that comprise an identification code readable in the vicinity of the identification modules, each identification code being assigned to an installation location of the identification module. The vehicle controller device is designed to set up a communication connection to a mobile device via the vehicle communication device to receive, via the communication connection, an identification code read out by the mobile device and, via the mobile device and the mobile communication connection, to allow or prohibit control or usage of individual or all vehicle functions and/or systems selectively on the basis of the received identification code.
US09499171B2 Driving support apparatus for vehicle
When a vehicle equipped with a driving support apparatus moves from an original traveling lane into a lane for passing in order to pass a preceding vehicle and an oncoming vehicle appears in the lane for passing, the safe passing of the preceding vehicle is determined to be impossible and the passing is interrupted even when the oncoming vehicle decelerates, in the case where a deceleration change amount of the oncoming vehicle is smaller than a threshold. On the other hand, when the deceleration change amount of the oncoming vehicle is equal to or greater than the threshold, whereby safety with respect to surrounding vehicles can be confirmed, and it is determined the vehicle can be safely returned in front of the preceding vehicle, the passing of the preceding vehicle is performed.
US09499169B2 Driving assistance device
A driving assistance device including: a preceding vehicle detection portion; a speed control portion controlling the speed adjustment to the host vehicle to obtain a target inter-vehicle distance; a preceding vehicle travel trajectory acquisition portion; an entering vehicle detection portion; an entering vehicle travel trajectory acquisition portion; a target trajectory setting portion setting the target travel trajectory of the host vehicle based on at least the travel trajectory of the preceding or the entering vehicle; a steer control portion controlling the adjustment of the steer amount calculated based on the target travel trajectory; and a location determination portion determining the location where the deviation amount between the travel trajectories of the entering and preceding vehicles becomes the predetermined value or below. The target trajectory setting portion sets the target travel trajectory of the host vehicle based on the travel trajectory of the entering vehicle, after the determined location.
US09499168B2 Vehicle periphery display device
Based on a vehicle driving condition indicated by vehicle control information, an image area to be displayed is determined from a panorama image of a vehicle periphery and a judgment is made about a collision possibility between a vehicle outside object appearing in the image area and the vehicle, so that a display image including the image area is generated and displayed on a display 16, and the vehicle is controlled to avoid its collision with the vehicle outside object according to a result of the judgment about the collision possibility.
US09499167B2 Automatic slot parking strategy
The present invention relates to a method for assistance in the parking of a vehicle from a roadway into a free parking space, by one or more maneuvers of the slot parking type, comprising the following steps: determination of the length of the free parking space, determination of an optimum path to be followed by the movement of the vehicle by successive arcs of a circle, characterized in that it comprises a step for determining the number of maneuvers Nm needed in order to bring the vehicle into the parking space and in that these maneuvers are implemented when this number of maneuvers Nm is less than a threshold S2.
US09499164B2 Controlling a clutch between an engine and a motor during a shift event in a hybrid vehicle
A hybrid electric vehicle includes an engine, an electric motor, a transmission gearbox, and a clutch selectively coupling the engine to the electric motor. Engine speed can drop dramatically when operating at high speeds during a scheduled shift event in the gearbox. To reduce the effects felt by the engine speed change, at least one controller is provided and programmed to slip the clutch when locked in response to a drive torque, estimated to be present upon completion of an anticipated shift event, exceeding available negative torque, such as regenerative torque and engine braking torque.
US09499163B2 Drive control device for hybrid vehicle
A drive control device for a hybrid vehicle is provided with a differential device including four rotary elements; and an engine, first and second electric motors and an output rotary member respectively connected to the four rotary elements. One of the four rotary elements is constituted by a rotary component of a first differential mechanism and a rotary component of a second differential mechanism selectively connected through a clutch, and one of the rotary components is selectively fixed to a stationary member through a brake. The drive control device releases one of the clutch and the brake when the engine is started in a drive mode in which the engine is at rest while the clutch and the brake are in an engaged state, selecting the one of the clutch and the brake to be released, depending upon a drive force generated during starting the engine.
US09499162B2 Hybrid vehicle
During acceleration in accordance with an operation of an accelerator pedal in HV traveling, an ECU performs engine rotation speed control for increasing an engine rotation speed in accordance with acceleration of a vehicle, by increasing discharge power of a power storage device to increase driving force of a motor generator and suppressing an output from an engine. The discharge power of the power storage device at the time when performing engine rotation speed control in a CD mode is greater than the discharge power at the time when performing engine rotation speed control in a CS mode.
US09499160B2 Hybrid vehicle
A control unit for a hybrid vehicle determines whether warming of an engine is insufficient in an outside electric power feed mode. When the warming of the engine is insufficient, it is determined whether current time is in an initial period of electric power feed. When the current time is in the initial period of the electric power feed, only electric power of an electric storage device is supplied to the outside in a state that the engine is off. When the current time is not in the initial period of the electric power feed, the engine is turned on, and only electric power generated in a motor is supplied to the outside. When the warming of the engine is sufficient, the electric power generated in the motor, the electric power of the electric storage device, or both of them are supplied to the outside.
US09499159B2 Vehicle control apparatus
A vehicle control apparatus uses a travel mode selection unit to select between an EV travel mode, an engine travel mode, and an engine generation mode depending on comparisons between an engine generated power cost, an EV effect, and a surplus electric energy. In such manner, according to a travel condition of a vehicle, an appropriate travel mode is selected for an improvement of fuel consumption efficiency. The vehicle control apparatus also computes a fuel consumption decrease or a fuel consumption increase for each of a plurality of travel modes based on an engine efficiency and an MG-INV efficiency. In such manner, fuel consumption increase/decrease for every travel mode may be computed.
US09499151B2 Brake system for vehicle
Provided is a brake system for a vehicle including an input side hydraulic system, an output side hydraulic system, a first and a second shutoff valves to shut off flowing of the brake fluid between the input side hydraulic system and the output side hydraulic system when closed, a first and a second out-valves through which the brake fluid flows into a reservoir unit when opened, and a control unit to control a motor cylinder device of the output side hydraulic system to generate the brake fluid pressure according to the operational amount of a brake pedal. The control unit opens one or both of the first and the second shutoff valves and the first and the second out-valves when output characteristic of the brake fluid pressure generated by the motor cylinder device shifts from basic characteristic.
US09499150B2 Emergency braking
A brake system for a railway vehicle comprises a service brake with control valves and an emergency brake with a emergency brake valve adapted to permit or prevent emergency brake pressure from reaching the service brake control valves. The emergency brake is actuatable by a signal on an emergency brake wire. The brake system further comprises an isolating circuit adapted to permit or prevent control of the service brake control valves.
US09499147B2 Vehicle brake system
The vehicle brake system includes a cylinder, an output piston disposed in the cylinder, an input piston disposed in the cylinder but separating from the output piston and defining a separation chamber therebetween, a brake pedal connected to the input piston, a reaction force generating device for generating an elastic reaction force, a separation lock valve for controlling the communication between the separation chamber and the reaction force generating device, a fade state judging portion to judge whether the friction brake device is in a fade state or not and a friction braking force control portion for changing the mode to the fade state when the fade state judging portion judged that the friction brake device is in the fade state, wherein a desired friction braking force can be assured even under the brake fade state.
US09499143B2 Brake system for a vehicle and method for operating a brake system of a vehicle
A vehicle brake system and method for operating same, having a master brake cylinder, a brake medium reservoir, and a first brake circuit, connected via a reservoir line to the brake reservoir, having at least one first wheel brake cylinder, a first wheel inlet valve associated with the first brake cylinder, a first pump, by which a first brake medium volume is pumpable from the reservoir line through the open first wheel inlet valve into the first brake cylinder, a continuously adjustable first wheel outlet valve, by which a first brake medium displacement from the first cylinder into the brake reservoir is controllable, and a connecting line having a spring-loaded non-return valve, via which a delivery side of the first pump is connected to the brake reservoir, a brake medium displacement from the brake reservoir to the delivery side of the first pump being prevented by the spring-loaded non-return valve.
US09499141B1 Sensor-triggering of friction and regenerative braking
In an emergency stop situation, the regenerative braking system is used to assist in rapid deceleration, by combining regenerative braking with conventional friction brakes. Sensors can also be used to trigger the braking systems, even before the driver is able to react. These sensors might include external cameras, ABS activation detection, radar and ultrasound.
US09499137B2 Brake control device for a vehicle
A brake control device for a vehicle has a master cylinder that converts an operating force of a brake pedal to a fluid pressure, a wheel cylinder installed in each wheel of the vehicle that generates a braking force by a fluid pressure introduced in each wheel, an introduction section that introduces the fluid pressure generated by the master cylinder, a first switching valve disposed in a fluid passage connecting the master cylinder and the wheel cylinder, and closes at system startup and opens at system non-startup/failure, a second switching valve disposed in a branch fluid passage connecting the master cylinder and the introduction section and opens at the system startup and closes at the system non-startup/failure, and a brake controller. When the system is started after the depression operation of the brake pedal, the brake controller closes the second switching valve.
US09499134B2 Hand-held cleaning device and vehicle configured to equip the same
A hand-held cleaning device for vacuuming debris is provided. The hand-held cleaning device a housing, a motor and a vacuum generator. The motor and vacuum generator are both disposed within the inner space of the housing. An intake is in fluid communication with the vacuum generator. The vacuum generator draws air through the intake so as to collect debris. A filter is disposed between the intake and an outtake so as to catch debris. The housing has an outer surface configured to be gripped by a single hand of a user and is dimensioned so as to fit within a purse or diaper bag of a user so as to be easily carried. A vehicle having a storage compartment configured to hold the hand-held device is also provided. The storage compartment may be disposed on the center console of the vehicle or the door of the vehicle.
US09499129B1 Methods and systems for using cloud services to assign e-keys to access vehicles
Methods and systems are provided. One method is for providing access to a vehicle. The method includes sending, by a server, an access code for the vehicle to a portable device. The access code is configured to be transferred by the portable device to the vehicle. Then, receiving, by the server, data from the portable device that is indicative that the portable device is located outside of the vehicle or proximate thereto. Sending, by the server, validation to the vehicle that the access code received by the vehicle was sent to the portable device, and then the vehicle is configured to send an electronic key to the portable device upon receiving the validation. The electronic key is associated with at least one privilege associated with use of the vehicle, and the at least one privilege is defined based on the access code.
US09499127B2 Swipe and tap verification for entry system
A system and method for providing access to a vehicle operation includes a first user-input interface, a second user-input interface, and a vehicle controller. The first user-input interface is configured to interact with a user via a swipe-up input. The second user-input interface is configured to interact with the user via an application independent of the swipe-up input. The vehicle controller is configured to control the vehicle operation in response to detecting a first swipe-type user-input via the first user-input interface and a second user-input via the second user-input interface within a predetermined time.
US09499125B2 Vehicle system for activating a vehicle component to provide vehicle access
A vehicle system for activating at least one vehicle component to provide access to a vehicle. A first receiver is operative to obtain a wireless signal at least comprising first identification data of an electronic device; a memory device storing at least second identification data; at least a second receiver being operative to check the presence of a matching vehicle access key, and the at least second receiver being operative to check the presence of a matching vehicle access key if the first identification data match the at least second identification data.
US09499123B2 Assembly for a belt retractor
An assembly for a belt retractor includes a vehicle-sensitive sensor and a holding fixture (10) for the sensor. The sensor and the holding fixture (10) have geometric designs that interact and are adjusted to each other so that the sensor can be mounted at various spatial orientations in the holding fixture (10). In a belt retractor for a vehicle seat belt comprising such assembly the holding fixture (10) is coupled with the sensor at a fixed position to the frame of the belt retractor in which a belt reel of the belt retractor is rotatably supported.
US09499120B1 Active bolster and bolster vent
An active bolster for an automotive vehicle includes a bladder that inflates an interior trim area of the vehicle to provide a cushion to an occupant during an impact. The bladder has a first wall and a second wall cooperatively defining an interior cavity. The bladder has a two stage vent for venting inflation gas supplied into the cavity during an impact event. The vent has a first aperture defining a first predetermined flow area when a pressure difference across the vent is substantially zero. A bendable member defines at least in part the first aperture. A weakened seam joins the bendable member to an adjacent feature of the bladder. When there is a predetermined pressure difference across the vent, the weakened seam is ruptured and the bendable member deflects to a second position defining a second flow area greater than the first flow area.
US09499116B2 Occupant protection device and program
An occupant protection device for protecting an occupant in frontal and oblique crashes. The occupant protection device operates an airbag and switches a load limiting restraint load of the seat belt between a first load limit value and a second lower load limit value. A switching unit switches the restraint load based upon the physique of the occupant, and lateral acceleration or movement of the occupant during an impact. The second load value is set for a small physique occupant. The load value is switched from the first to the second load value after a predetermined time if the lateral acceleration or occupant movement falls below predetermined levels. For a large physique occupant with lateral acceleration or movement exceeding predetermined levels, the load limiter does not switch to the second load value after the predetermined time.
US09499112B1 Protective panels for a vehicle and method of manufacture
A method of manufacturing one or more protective panel for a vehicle that comprises affixing plastic sheeting to a vehicle surface; magnetically coupling at least one magnet strip over the plastic to the surface; spraying a heated mixture of thermoplastic polyurethane and polyurea on the sheeting over the at least one magnet; drying the mixture into a body; cutting at least one panel from the body. The panels are cut according the shape of the surface area to protect, after which the plastic is removed from the cut panel shapes.
US09499110B2 Automotive instrument operating device and alert device
An automotive instrument specifying unit of an automotive instrument operating device specifies a group of automotive instruments on the basis of the direction of gaze of an occupant detected by a gaze direction detector, and specifies one automotive instrument from among the specified group of automotive instruments on the basis of the up/down direction selected by up/down direction selecting unit when the up/down direction selecting unit has been operated in a state in which the group of automotive instruments has been specified.
US09499109B2 Trailer communication system
Implementations of the present disclosure involve an apparatus and/or method for a modular communication system for use in a tractor trailer to monitor and/or control various components associated within the trailer. In one particular embodiment, the communication system includes encryption/decryption controller boards configured to encrypt/encode messages or signals received at the boards for transmission along a transmission media between the front controller board and rear controller board. Further, one or both of the controller boards may be configured to decrypt/decode messages or signals received at the boards from the other controller board and perform a function in response to the decrypted message. The communication system may also integrate and communicate with several modules within or associated with the trailer, such as sensors, locators, or communication mechanisms.
US09499106B2 Pickup truck mounted toolbox
A pickup truck toolbox can be mounted to the bed side rails by feet rather than arms and may sit above the side rails and the bed volume, thus allowing use of the full volume of the bed between the side rails and the floor of the bed. It may have a rear view tunnel through it, whereby the driver may use normally the rear view mirror, and may have a Liddy light valley across the top, whereby the brake light will remain visible. The profile may match or sit within the profile of the cab of the truck, a fairing may be employed to improve fuel efficiency, and side-mounted vertical hatches may allow both easy access and the use of shelving.
US09499095B1 Emergency vehicle accessory
An emergency vehicle control system with functional warning units for use in an emergency vehicle provide active visual and audible alerts. The functional warning unit includes a set of alert devices, each alert device having at least one functional connection and a remote controller, connected to the set of alert devices and configured to receive an encoded message on a single data line from a central controller. The remote controller is configured to decode the encoded message to a set of desired states for each of the set of alert devices. The remote controller is configured to control the set of alert devices, by way of the at least one functional connection, according to the respective desired state of each of the set of alert devices.
US09499090B2 Spoiler using photoluminescent illumination
An illumination system for a vehicle includes a rear spoiler with first and second photoluminescent portions disposed on the spoiler and at least one light source configured to emit an emission at a first wavelength. The first and second photoluminescent portions are configured to convert the first wavelength to at least a second wavelength longer than the first wavelength.
US09499089B2 Automotive exterior lamp assembly with charge port
A vehicle includes a battery charger and an exterior lamp assembly. The assembly includes a housing defining a cavity, and an electrical port including at least one electrical terminal disposed within the cavity, electrically connected with the battery charger, and configured to be electrically connected with an electrical power grid remote from the vehicle.
US09499084B2 Apparatus for adjusting height and angle of footrest support for construction equipment
An apparatus for adjusting a height and an angle of a footrest support for a construction machine is disclosed, which can adjust the height and the angle of the footrest support, on which an operator puts his/her foot, in accordance with physical conditions of the operator. The apparatus includes pedal plates, a pedal arm having one end fixed to a second bracket and the other end having a through-hole for adjustment of a height of the pedal plate, a fixing plate installed in a predetermined position of the pedal arm, a fixing pin coupled to the through-hole of the fixing plate and a fastening plate installed in predetermined positions of left and right sides in a cabin and having fastening holes for adjustment of the height of the pedal plate formed thereon at equal intervals in upward and downward directions.
US09499083B2 Tray table structure
Described are tray table assemblies comprising a table body including a frame. The frame is formed of an upper bar and a lower bar that connect a pair of slide guides, wherein the upper bar, the lower bar, and the pair of slide guides are integrally formed as a single piece.
US09499082B2 Motor vehicle
Each side bar of a vehicle seat structure has a respective front longitudinal profile and a respective rear longitudinal profile. The front longitudinal profile has a cross-section that enables an elongation of the front longitudinal profile under a tensile stress on the front longitudinal profile. The rear longitudinal profile has a cross-section that enables a compression of the rear longitudinal profile under a bending moment stress on the rear longitudinal profile. The elongation of the front longitudinal profile and the compression of the rear longitudinal profile lead to an absorption of energy.
US09499080B2 Vehicle seat back member
A vehicle seat back member includes a central web and a front wall that extends from the central web. A rear wall extends along a substantial portion of a rear edge of the central web. A shear center load path of the vehicle seat back member is disposed proximate an inside corner defined by the connection of the central web and the rear wall, and extends substantially along the longitudinal extent of the rear wall.
US09499073B2 Slide rail of vehicle seat
A slide rail of a vehicle seat includes a first rail to which a screw having a screw thread formed on an outer periphery is fixed; a second rail that retains a nut into which the screw screws, and moves relative to the first rail by the nut rotating; a protruding portion that is provided on the first rail, and protrudes toward the screw; and an elastic member that connects the protruding portion and the screw. The elastic member has a retaining body that retains the screw, and an engaging body that engages with the protruding portion.
US09499069B2 Systems and methods for adjusting the position of a wheelchair occupant
A system for adjusting a position of a wheelchair occupant includes a sensor configured to generate sensor data based on the position of the occupant, an adjustable cable system coupled to a support point on the wheelchair and configured to be coupled to a support point on the occupant's clothing, and a processing circuit. The cable system is configured to extend and retract at least one cable to adjust the position of the occupant, and the processing circuit is configured to determine the position of the occupant in the wheelchair based on the sensor data and adjust the cable based on the determined position of the occupant.
US09499066B2 Method for determining a charge acceptance, and method for charging a rechargeable battery
In the case of a method for determining a charge acceptance ICA of a rechargeable battery, the battery is computationally split up into a predetermined number n of compartments i having a respective maximum charge capacitance Ci, which are connected in parallel via resistances Ri, and the charge acceptance ICA of the battery is determined on the basis of the charge capacitance C1 and the resistance R1 of the compartment adjacent to the battery terminals. The invention also relates to a method for charging a rechargeable battery.
US09499061B2 Charging plug with locking identification
A charging device for an electric vehicle, which charging device can be protected against unauthorized access in a particularly reliable manner. The charging device for an electric vehicle has a bolt for locking a connection between the charging device and a further charging device. If the charging device is mechanically connected to a further charging device for charging purposes, this mechanical connection is then locked by a corresponding end of the bolt being moved into a retaining opening in the further charging device. A retaining opening of this kind can, for example, be damaged by a broken web which serves for locking such that locking is no longer possible. Therefore, a device is provided which can prevent movement of the bolt in the direction of a locking position when the retaining opening is damaged in this way. A locking arrangement which is damaged in the above manner therefore fundamentally does not remain unnoticed. Charging therefore preferably requires sufficiently undamaged, correct locking of the two charging devices involved.
US09499058B2 Electric charging apparatus and operation method thereof
An electric charging apparatus is provided. The electric charging apparatus includes a ground determination signal generating unit measuring a current signal or voltage signal that is generated from power applied from a power supply unit, the ground determination signal generating unit generating a signal for determining whether the power supply unit is normally grounded on the basis of the current or voltage signal, a power control unit generating a power control signal on the basis of a ground determination detecting signal generated from the ground determination signal generating unit, and a power cutoff unit cutting power supply to a target device to be charged on the basis of the power control signal.
US09499054B2 Charge depleting mode control system for plug-in hybrid vehicle and method thereof
A charge depleting mode control apparatus of a plug-in hybrid vehicle includes a driving information detector, a mode determining unit, a shift-speed determining unit, a shift determining unit. The driving information detector detects driving information of a vehicle. The mode determining unit determines whether a charge depleting (CD) mode is entered by using a state of charge (SOC) of a battery provided from the driving information detector. The shift-speed determining unit determines a target shift-speed when the mode determining unit determines to enter the CD mode. The shift determining unit determines whether to change the shift-speed determined by the shift-speed determining unit. The shift-speed is determined by using transmission efficiency and motor efficiency when the plug-in hybrid vehicle drives in the CD mode, such that fuel consumption is reduced and performance is improved.
US09499053B2 Electromotive vehicle having energy and power batteries, and control method for the same
A hybrid vehicle includes electrical storage devices, a charging device, a motor generator, a diode, an outlet and a relay. The first electrical storage device stores driving electric power. The charging device charges the first electrical storage device with the user of a power supply outside the vehicle. The motor generator has a power generation function. The second electrical storage device stores electric power that is generated by the motor generator. When electric power is output to a device outside the vehicle from the outlet, the relay limits electric power, which is output from the first electrical storage device, such that electric power stored in the second electrical storage device is output.
US09499048B2 Support arm assembly
The present application relates to a support arm assembly (39) for mounting in a fuel tank (1). A support arm (43) is provided to support a fuel transfer tube (17) for transferring fuel to a fuel pump (11). A support foot (49) is provided to support the support arm (43) at a predetermined position within the fuel tank (1). The support foot (49) biases the support arm assembly (39) against a roof of the fuel tank (1). The present application also relates a support foot (49) for mounting in a support arm assembly (39). The combination of a fuel tank (1) and the support arm assembly (39) is also envisaged.
US09499040B2 Method and apparatus for managing charge depletion in a plug-in hybrid vehicle
A plug-in hybrid vehicle includes a hybrid powertrain system and an energy storage device. A method for operating the hybrid powertrain system includes initially operating the hybrid powertrain system in a charge-depletion mode to reduce a state-of-charge (SOC) of an energy storage device. In response to an operator request, the hybrid powertrain system operates in an opportunity charging mode to opportunistically charge the energy storage device to increase the SOC of the energy storage device during a trip prior to achieving a minimum SOC that is associated with triggering operation in a charge sustaining mode.
US09499038B2 Integrated hybrid power assembly and vehicle comprising the same
An integrated hybrid power assembly and a vehicle including the same. The integrated hybrid power assembly includes a transmission comprising a front housing and a rear housing, a drive motor comprising a motor housing integrated with the rear housing of the transmission and a motor cover mounted to the motor housing, a speed reducer comprising a reducer housing, which is fixedly connected to the rear housing of the transmission and integrated with the motor cover of the drive motor, and a speed reducer cover mounted to the reducer housing; and a starting motor mounted to the transmission.
US09499033B1 Modular top for a vehicle
A modular top system for a vehicle is provided. In various embodiments, the system includes a plurality of rail sections, a plurality of corner brackets for connecting the rail sections to form a frame, and a flexible, collapsible cover to be deployed over and connected to the frame. The modular top system can additionally include a plurality of cover connecting devices disposable on a periphery of each of the sides of the cover. Each connecting device is for removably connecting each respective cover side to the frame to deploy the cover over and connect the cover to the frame. Each rail section can comprise at least one assembly connector for connecting any of a plurality of system assembly components to the respective rail section, and/or at least one accessory connector for connecting at least one modular top accessory to the respective rail section.
US09499032B2 Vehicle back door structure
A vehicle back door structure including: a back door panel made of resin having, in at least a part of a peripheral edge thereof, a recessed portion equipped with a pair of side walls and a bottom wall that interconnects vehicle front sides of the pair of side walls, with a step portion, that has one side-wall side positioned at a vehicle rear side of another side-wall side, being formed in the bottom wall; and a reinforcement rib that is formed integrally with a vehicle rear side surface of the bottom wall, that straddles the step portion, and that bridges the pair of side walls.
US09499031B2 Rear door device in vehicle
A rear door device for a vehicle may include a rear door, an upper rail mounted to the rear door in a width direction, an upper slider inserted in the upper rail to support the upper rail, a lower rail mounted to a vehicle body and formed with a curved portion, a lower slider inserted in the lower rail and movable along the lower rail, an upper support structure having one end connected to the upper slider and the other end mounted to the vehicle body for supporting the upper slider, and a connection structure for connecting the lower slider to the upper rail. The rear door device permits the rear door to be opened or closed by sliding it forward or backward in the length direction of the vehicle.
US09499016B2 Valve stem for coupling a TPMS wheel unit to a wheel rim, TPMS wheel unit and valve stem assembly and installation thereof
A valve stem for coupling a TPMS wheel unit to a wheel rim, TPMS wheel unit and valve stem assembly and installation thereof are disclosed. The valve stem comprises a bulb, an inner tubular member, and an outer tubular member; the inner tubular member and the outer tubular member being fixedly attached to the bulb.
US09499015B2 Rotary feedthrough for a vehicle wheel
A rotary feedthrough for a motor vehicle wheel having tire pressure regulation comprises a wheel carrier and a wheel hub rotatably supported on the wheel carrier. A compressed air annular space and at least one annular lubricant space, which are sealed with respect to one another, are configured in an intermediate space between the wheel carrier and the wheel hub. In this respect, the compressed air annular space communicates with a compressed air passage of the wheel carrier and with a compressed air passage of the wheel hub, wherein the compressed air passage of the wheel hub communicates with a controllable valve in order selectively to fill a tire of the motor vehicle wheel with compressed air or to deflate the tire. The annular lubricant space in turn communicates with a lubricant passage of the wheel carrier and with a lubricant passage of the wheel hub, wherein the lubricant passage of the wheel hub leads to a control port of the valve in order selectively to control the valve for the passage of compressed air.
US09499013B2 Pneumatic tire
The present invention provides a pneumatic tire 1, comprising: a carcass ply including a main body portion 11a extending across respective bead cores 9 and turn-up portions 11b each turned up around the bead cores 9 from the main body portion 11a; a bead filler 13; and a side rubber 5a, wherein: a tip portion on the outer side in the tire radial direction of the outer end 13a of the bead filler 13, of each of the turned-up portions 11b, extends to a position of at least 5 mm distance from the outer end 13a of the bead filler with maintaining distance of 1 mm or less between the main body portion 11a and itself; a turn-up end 11c is disposed on the inner side in the tire widthwise direction than a neutral axis of bending of a bead portion 7 and a corresponding sidewall portion 5 and at 10%-40% height of a tire cross sectional height SH of the tire; and the side rubber 5a, disposed on the outer side in the tire widthwise direction of the main body portion 11a and each turn-up portion 11b, covers the turn-up end 11c and constitutes a part of an outer surface of the tire.
US09499012B2 Pneumatic tire
In a pneumatic tire, the groove width of the connecting subsidiary grooves changes midway. The relationship between the groove width (W1) connecting to the circumferential main groove on the outer side in the tire width direction and the groove width (W2) connecting to the circumferential main groove on the inner side in the tire width direction satisfies the range of 0.30≦W1/W2≦0.70. The relationship between the groove length (L1) on the tread surface having a region of groove width (W1) and the groove length (L2) on the tread surface having a region of groove width (W2) satisfies the range of 0.25≦L2/L1≦0.65. Sipes are provided on the tread surface of the block-like land portions. The respective end portions of the sipes connect to a position where the groove width (W1) of the connecting subsidiary grooves changes to the groove width (W2).
US09499010B2 Pneumatic radial tire
A pneumatic radial tire including a carcass; two belt reinforcing layers; and a belt formed by two belt layers. A width of a belt cord intersecting region defined by the two belt layers is set in the range of 65 to 90% of the tire width-W, the maximum width of the belt reinforcing layer is set in the range of 60 to 85% of the tire width. Also, a belt radius ratio, which is a ratio of difference between the radius of the belt at the tire equatorial plane and the radius of the belt at a belt side end position thereof measured from the tire axis in a state where the tire is inflated at the standard inner pressure, with respect to a belt half width, is not larger than 0.06.
US09499008B2 Vehicle wheel
The invention concerns a vehicle wheel, comprising a body of a plastics material and at least one adapter for fastening the body to a wheel mounting, the at least one adapter having at least one protuberance which engages in a recess in the body, or, if multiple adapters are used, at least one adapter is formed such that it engages in a recess of the body over its full surface area, the adapter being arranged in such a way that, after assembly of the body on the wheel mounting, the adapter is positioned between the body and the wheel mounting, or the adapter being arranged in such a way that the body is positioned between the wheel mounting and the adapter, so that the adapter lies on the outside of the body after assembly.
US09499002B2 Resin printing plate precursor for laser engraving
It is an object of the present invention to provide a resin printing plate precursor for laser engraving that is able to form a relief by laser engraving, the relief having excellent image reproducibility, and moreover has toughness and improved printing durability. The present invention is a resin printing plate precursor for laser engraving comprising a substrate and a resin layer on the substrate, the resin layer containing: (A) a modified partially saponified polyvinyl acetate having reactive groups in its side chain; (B) a polyamide having basic nitrogen; (C) a compound having a 5- to 7-membered ring and a polymerizable ethylenic double bond; and (D) a photopolymerization initiator.
US09499001B2 Image elimination apparatus, image eliminating method and image forming apparatus
According to an embodiment, an image elimination apparatus eliminates an image formed on a sheet. A sheet supply unit supplies the sheet on which the image is formed. A first reader reads the sheet supplied by the sheet supply unit. An image eliminator eliminates the image formed on the supplied sheet. A second reader reads the sheet passing through the image eliminator. A discharge unit stacks the sheet to be discharged. A controller causes the first reader to read the sheet at a first speed in order to judge whether the sheet is reusable or not based on the reading result of the first reader. The controller also causes the second reader to read the sheet at a second speed faster than the first speed in order to judge whether the image formed on the sheet has been eliminated or not based on the reading result of the second reader.
US09498999B2 Laser marking
There are described compositions and methods for the laser marking of products or their packaging. The compositions comprise transition metal oxides, saccharides and/or flame-retardant agents, optionally with other additives, dispersed in a carrier.
US09498996B2 Ink ribbon cassette, ink ribbon cartridge, printing device and control method for printing device
An ink ribbon cartridge may include a supply roll; a winding roll; and a power transmission mechanism to transmit power from a drive source to the supply roll and the winding roll. A direction in which an ink ribbon is wound by the winding roll is a ribbon winding direction and a direction in which the ink ribbon is wound by the supply roll is a ribbon rewinding direction. The power transmission mechanism may include a winding side one-way clutch to transmit a driving force in the ribbon winding direction to the winding roll and cut off transmission of the driving force in the ribbon rewinding direction to the winding roll; and a supply side one-way clutch to transmit the driving force in the ribbon rewinding direction to the supply roll and cuts off transmission of the driving force in the ribbon winding direction to the supply roll.
US09498994B2 Tape cartridge
A tape cartridge is detachably installed on a cartridge installation portion of a tape printing apparatus having a platen supporting shaft and a printing head, a base end of the platen supporting shaft being fixed to the cartridge installation portion at one end of the platen supporting shaft and extending in an attaching/detaching direction of the tape cartridge. The tape cartridge has a platen roller through which the platen supporting shaft passes when the tape cartridge is installed on the cartridge installation portion and which receives a pressing force from the printing head when a printing operation is performed in a state in which the tape cartridge is installed on the cartridge installation portion, and a fitting portion in which a tip end of the platen supporting shaft passing through the platen roller fits when the tape cartridge is installed on the cartridge installation portion.
US09498993B2 Image processing apparatus, image processing method, and medium storing program
Judgment image data having a resolution in a direction in which a printing medium is conveyed which is lower than a printing resolution is generated based on input image data. It is determined whether color unevenness is generated in a printed image by comparing the judgment image data with reading data obtained by reading the printed image.
US09498988B2 Tape cassette
A tape cassette includes a box-like housing, a tape mounted within the housing, a hole and a first indicator portion. The housing includes a top wall having a top surface, a bottom wall having a bottom surface and opposing the top wall, and a front wall having a specified height and being formed along peripheries of the top wall and the bottom wall. The hole is provided in the front wall. The first indicator portion includes at least one first aperture and indicates a first element among a plurality of elements of a type of the tape. The first indicator portion is provided in a portion, spaced from the front wall, of the bottom wall. The hole and the one first aperture is located to intersect a virtual line orthogonal to the front wall when viewing along a vertical direction orthogonal to the top wall and the bottom wall.
US09498983B1 Printing apparatus that cuts off a printed portion of an unwound sheet and method for printing an image
A printing apparatus includes a housing, a conveying unit configured to unwind a portion of a rolled sheet and convey the unwound sheet, a printing unit configured to print an image on the unwound sheet, a cutter configured to cut off a portion of the unwound sheet, and a sheet sensor configured to detect a portion of the unwound sheet conveyed out of the housing and, upon detecting the portion, output a detection signal that causes the cutter to cut off the unwound sheet.
US09498979B2 Pressing unit and liquid ejecting apparatus
A pressing unit used for pressing a pressing member into a pressing target includes a plurality of attachment portions to which the pressing member is attached, in a detachable manner; and a pressing force generation mechanism which generates different pressing forces in each of the attachment portions.
US09498972B2 Printer and printing system
In a system of a data processing apparatus coupled to a printer, the apparatus sends a status information transmission request to the printer and, in response, receives status information from the printer. The status information includes ink storage identification information written in a memory contained in an ink storage, device identification information identifying the printer in which the ink storage is installed, and ink usage amount information for use by the printer in calculating a remaining ink amount.
US09498968B2 Recording apparatus
A recording apparatus includes an opening section 30 which is formed on an outside surface of a housing 25 and through which a sheet cassette 29 is inserted, ink containers 17a and 17b that store ink, cases 18 that are disposed on outside surfaces on both sides adjacent to an outside surface on which the opening section 30 of the housing 25 is formed and holds the ink containers 17a and 17b, and a tube that supplies the ink from ink containers 17a and 17b to the inside of the housing 25, in which sizes of the cases 18 on both sides are different from each other.
US09498965B2 Cartridge without an inadmissible overpressure
The invention relates to an ink and/or solvent cartridge (10) for an industrial printer, such a cartridge including at least one semi-rigid or deformable volume (14), being provided with an aperture (16), and having a given maximum capacity VCmax, and holding a hermetically enclosed volume of liquid comprising an ink and/or a volatile solvent, and a gas volume, the sum of these 2 volumes being lower than the maximum capacity VCmax, and in the whole temperature range between 10° C. and 35° C. and for a 1 bar pressure.
US09498960B2 Passive actuators for printhead cleaning using mobile maintenance carts
A maintenance system for a three-dimensional object printer includes a platform having a plurality of wheels that enable the platform to move along a first track, and having a maintenance mechanism connected to the platform so as to be movable normal to the first track. The maintenance mechanism includes a lifting member that extends laterally from the platform, and a maintenance tool configured to move with the lifting member. A lifting platform is positioned laterally offset from a location of the first track where an ejector head is positioned opposite the first track, and is configured to engage with the lifting member to lift the maintenance tool and enable the maintenance tool to perform a maintenance operation on the ejector head.
US09498959B2 Maintenance unit and liquid ejection device
A maintenance unit mounted in a removable manner in a liquid ejector that ejects liquid. The maintenance unit includes an elongated maintenance member, which is used to perform maintenance on the liquid ejector, and a memory, which is configured to store information related to the maintenance member.
US09498955B2 Printing device and printing method for discharging ink from nozzle row including nozzle groups
A printing device includes a printing head and a control unit. The printing head has a nozzle row with a one end side nozzle group of nozzles of one end side of the nozzle row, an other end side nozzle group of nozzles of an other end side of the nozzle row, and a center nozzle group of nozzles of the nozzle row, which does not correspond to the one and other end side nozzle groups. The control unit is configured to discharge the ink on a designated area on a print medium from the nozzles included in the center nozzle group and the other end side nozzle group with a first movement of the printing head and discharge the ink on the designated area from the nozzles included in the center nozzle group and the one end side nozzle group with a second movement next to the first movement.
US09498951B2 Inkjet nozzle device having dual chamber inlets and twofold symmetry
An inkjet nozzle device includes: a nozzle chamber having a floor, a roof and perimeter sidewalls extending between the floor and the roof, wherein a nozzle aperture is defined in the roof; a heating element for generating gas bubbles in the nozzle chamber so as to eject ink through the nozzle aperture, wherein a centroid of the heating element is aligned with a centroid of the nozzle aperture; and a pair of chamber inlets defined in the floor of the nozzle chamber, the chamber inlets being symmetrically disposed about the centroid of the heating element. The inkjet nozzle device has a pair of orthogonal symmetry planes passing through the centroid of the nozzle aperture.
US09498947B2 Method for creating tamper-evident labels
A method for creating a tamper-evident label is described. Embodiments of the method or process typically include four steps. In a first step, an ultraviolet cured ink mask can be printed onto a substrate by an inkjet printer. In a second step, once the printing is done and the mask has been formed, the substrate can be anodized in a weakened anodizing bath. In a third step, the ultraviolet cured ink can be removed from the substrate leaving a portion of the substrate unanodized. To remove the ultraviolet cured ink, the substrate can be heated to an elevated temperature and a cleaning solution and/or solvent can be applied to the ultraviolet cured ink mask. In a fourth step, the substrate can be anodized for a second time.
US09498944B2 Pressuring module, pressuring apparatus, substrate bonding apparatus, substrate bonding method, and bonded substrate
A pressuring module includes a stage having a mounting surface on which an object to be pressured is mounted; a plurality of pressure detecting sections that detect a pressure applied on the mounting surface; and a pressure varying section that varies a pressure distribution across a plane of the mounting surface, by differing a pressing force against the object to be pressured between a periphery and a central portion of the mounting surface in a plane direction of the mounting surface based on the pressure detected by the plurality of pressure detecting sections.
US09498943B2 System for laminating optical film and method for manufacturing display unit using the same
A system for laminating an optical film according to an exemplary embodiment of the present disclosure includes a panel transfer unit to transfer a panel, a first laminating unit installed on a transfer line of the panel to laminate an optical film on a first surface of the panel along a first direction parallel to a transfer direction of the panel, and a second laminating unit installed on the transfer line of the panel to laminate an optical film on a second surface of the panel, wherein the second laminating unit includes a laminating drum to laminate an optical film after adsorbing and rotating the optical film in a horizontal direction.
US09498940B2 Cover window and apparatus and method for manufacturing the cover window
Provided are a cover window and an apparatus and method for manufacturing the cover window. The cover window includes a film layer having at least one bent portion, a resin layer having at least one bent portion, and an adhesive layer disposed between the film layer and the resin layer and adhering the film layer and the resin layer.
US09498939B2 Meltblown-spunbonded-meltblown laminated fabric
There is disclosed a laminated, nonwoven fabric and a process for producing such a laminated, nonwoven fabric having desirable fluid holding and fluid release characteristics. The process provides that two sheets of meltblown fiber fabric are produced on forming wire assemblies, cooled at a cooling area, and are then laminated on opposite sides of a sheet of spunbonded fibers using to form the laminated, nonwoven fabric.
US09498938B2 Laminating device and laminating method using the same
A laminating apparatus and method are disclosed. The laminating device includes a first jig, a second jig facing the first jig, an auxiliary film fixing unit and a driving unit. A partially curved cover window is seated on the first jig. An auxiliary film and a panel member are seated on the second jig so as to be flat. The driving unit linearly moves at least one of the first and second jigs.
US09498936B2 Multilayer barrier structures, methods of making the same and packages made therefrom
Multilayer structures, methods of making the same and packages made therefrom are provided. The multilayer structures are useful for packaging bone-in meat or other like products. More specifically, the multilayer structures have sufficient rigidity and strength to contain bone-in meat or other like products, while also maintaining good oxygen barrier properties. In addition, multilayer structures can easily seal to themselves or to other structures. Moreover, the multilayer structures are biaxially oriented and heat-shrinkable.
US09498932B2 Multi-layered meltblown composite and methods for making same
Multilayer meltblown composites, articles made therefrom, and methods for making same. One method can include meltblowing a first material to form a first meltblown layer; meltblowing a second material to form a second meltblown layer; and meltblowing a third material to form a third meltblown layer, wherein each material is the same or different, each material includes at least one resin having a MFR of about 2,000 dg/min or less, as measured by ASTM D1238, 2.16 kg, 230° C., and at least one of the first, second, and third materials comprises an elastomer having a recovery of at least 70% after 100% deformation, as determined by ASTM D412.
US09498931B2 Energy efficient construction materials
A roofing shingle may include a substrate, granules and multilayer infrared light reflecting film particles. In some cases, a roofing shingle may include a substrate, granules and a multilayer infrared light reflecting film disposed either above or below the granules. Such roofing shingles may exhibit improved solar reflectivity. An infrared light reflecting mixture may include inorganic granules and polymeric multilayer infrared light reflecting film particles. An existing construction surface may be treated to improve its solar reflectivity.
US09498927B2 Decorative foam and method
Decorative foamed articles are prepared from foamed pellets, beads, particles, or other articles of a thermoplastic elastomer infused with a supercritical fluid in a pressurized container, then rapidly depressurized and heated either by immersion in a heated fluid that can rapidly heat the article or with infrared or microwave radiation to heat and foam the pellets, beads, particles, or other articles that are then molded into the articles. The pellets are dyed with a nonionic or anionic dye one of: (1) before being infused with the supercritical fluid, (2) during being infused with the supercritical fluid by a nonionic or anionic dye dissolved or dispersed in the supercritical fluid, which optionally comprises a polar liquid, (3) during immersion in the heated fluid, where the heated fluid contains the dye, or (4) after being foamed.
US09498924B2 Ophthalmic lens molds with low levels of UV light transmittance, ophthalmic lenses molded therein, and related methods
Ophthalmic lens molds made from one or more thermoplastic polymer having a low level of UV light transmittance (UV % T) ophthalmic lenses including silicone hydrogel contact lenses molded using these thermoplastic polymer having low UV % T, and methods of manufacturing ophthalmic lenses by cast molding a polymerizable composition in mold members formed of these thermoplastic polymers having low UV % T and curing the polymerizable composition using UV light are described.
US09498923B2 Method for treating a fiber-plastic composite of a rotor blade, semifinished product in the form of a composite structure and UV lamp for curing a UV-curable matrix material
The invention relates to a method for treating a fiber-plastic composite of a rotor blade, comprising the steps of: providing the fiber-plastic composite to be treated at the rotor blade; preparing a local working area of the fiber-plastic composite; providing a fiber-matrix composite comprising a UV-curable matrix material and a fiber material; applying the fiber-matrix composite onto the local working area of the fiber-plastic composite; and curing the matrix material. The invention provides for the curing of the matrix material to take place with the help of UV radiation.
US09498922B2 Apparatus and process for producing porous devices
In general, in various embodiments, the present disclosure is directed systems and methods for producing a porous surface from a solid piece of polymer. In particular, the present disclosure is directed to systems that include a track assembly, mold assembly, press assembly, and methods for using the same for producing a porous surface from a solid piece of polymer. In some embodiments, the present systems and methods are directed to processing a polymer at a temperature below a melting point of the polymer to produce a solid piece of polymer with an integrated a porous surface.
US09498920B2 Method and apparatus for three-dimensional fabrication
The present invention relates to methods and an apparatus for the fabrication of solid three-dimensional objects from liquid polymerizable materials.
US09498919B2 3D printing with small geometric offsets to affect surface characteristics
This document describes techniques and apparatuses for 3D printing with small geometric offsets to affect surface characteristics. These techniques are capable of enabling fused-deposition printers to create 3D objects having desired surface characteristics, such as particular colors, images and image resolutions, textures, and luminosities. In some cases, the techniques do so using a single filament head with a single filament material. In some other cases, the techniques do so using multiple heads each with different filaments, though the techniques can forgo many switches between these heads. Each printing layer may use even a single filament from one head, thereby enabling surface characteristics while reducing starts and stops for filaments heads, which enables fewer artifacts or increases printing speed.
US09498918B2 Method and device for embossing
A process for embossing a structure in an embossing material that is applied on a substrate comprising the steps of embossing the embossing material by an embossing die and hardening the embossing material, wherein at least the substrate and/or the embossing die and/or at least one heating layer arranged between the substrate and the embossing material and/or between the embossing die and the embossing material are irradiated by means of microwaves for hardening the embossing material.
US09498916B2 Chuck device and hoop winding device
A chuck device of a fiber bundle includes a pair of hands adapted to be opened/closed. The pair of hands includes a plurality of guides adapted to regulate and bend the fiber bundle under a closing state, and to release the fiber bundle under an opening state. Under the closing state, the plurality of guides holds the fiber bundle by being close to each other with tension applied on the fiber bundle.
US09498915B2 Fabrication of reinforced thermoplastic composite parts
A method of fabricating a reinforced thermoplastic composite part comprises moving a laminate of reinforcing fibers embedded in a thermoplastic matrix for sequential operations through a heating station and then a forming station. The heating station is used to soften the thermoplastic matrix in a portion of the laminate while the forming station is used to impart a geometry to a portion of the laminate whose thermoplastic matrix had just been softened. The softening and the forming are performed simultaneously on different portions of the laminate.
US09498914B2 3D microfluidic devices based on open-through thermoplastic elastomer membranes
The invention provides a new process for patterning TPE membranes for use in the design and fabrication of 3D microfluidic devices. The process involves patterning a TPE material without permitting the highest features of the mold to come into contact with the counter-plate, whereby adhesion between the TPE and the mold or counter-plate during demolding results directly in removal of the excess layer from the TPE membrane to produce well formed micrometric-sized open-through holes in the TPE membrane. The process permits rapid, reliable and efficient patterning of densely packed and arbitrarily placed micrometric open-through holes and channels of high aspect-ratio and any shape or wall profile in thin TPE membranes.
US09498910B2 Injection assembly for a molding machine
An injection assembly (1) for a molding machine (2), in particular an injection molding machine, comprising an injection piston (3), a drive device (4) for moving the injection piston (3), and a force storage means, wherein the force storage means connects the drive device (4) to the injection piston (3).
US09498909B2 Injection molding flow control apparatus and method
A method and apparatus for performing an injection molding cycle comprising drivably interconnecting a valve pin to an electric motor actuator and controllably operating the electric motor to drive the valve pin at one or more reduced rates of upstream or downstream travel based on either detection of the position of the pin or actuator or on a preselected length of time at which to drive the valve pin.
US09498898B2 Cleaning mechanism for semiconductor singulation saws
A cleaning subsystem removes unwanted material, such as glaze, from saw blades used in a semiconductor singulation process. A cleaning module moves radially towards the saw blade and vertically with respect to the plane of the saw blade in order to enable abrasive cleaning blocks of the cleaning module to selectively remove material from either the upper and lower surfaces of the saw blade or the outer edge of the saw blade. The cleaning assembly can remove material from the saw blade at a predetermined time or position during the singulation process or upon detection of load imbalance during the rotation of the saw blade.
US09498889B1 Double action, out the front, automatic knife
A knife include a handle, button, blade with an integral tang, locking mechanism within the tang, and thrust mechanism. The blade moves between closed and open positions. The button axially slides along the handle. When the blade is in the closed position and locked, movement of the button towards the first handle end releases the locking mechanism and the thrust mechanism moves the blade to the open position. When the blade is in the open position and locked, movement of the button towards the second handle end releases the locking mechanism and the thrust mechanism moves the blade to the closed position. A knife includes a stop pin connected to a tang of a blade and a stop plate positioned within a knife handle. The stop plate has two angled surfaces. The stop pin mates with both angled surfaces and the blade is constrained from movement in two planes.
US09498888B2 Articulating instrument
The invention provides an articulating mechanism useful, for example, for remote manipulation of various surgical instruments and diagnostic tools within, or to, regions of the body. Movement of segments at the proximal end of the mechanism results in a corresponding, relative movement of segments at the distal end of the mechanism. The proximal and distal segments are connected by a set of cables in such a fashion that each proximal segment forms a discrete pair with a distal segment. This configuration allows each segment pair to move independently of one another and also permits the articulating mechanism to undergo complex movements and adopt complex configurations. The articulating mechanisms may also be combined in such a way to remotely mimic finger movements for manipulation of an object or body tissue.
US09498883B2 Multi-joint underwater robot having complex movement functions of walking and swimming and underwater exploration system using same
Disclosed is an underwater exploration system using a multi-joint underwater robot having a novel complex movement concept in which the multi-joint underwater robot moves through walking or swimming with multi-joint legs closely to a seafloor, differently from a conventional underwater robot to obtain a thrust through a propeller scheme. The underwater exploration system includes the multi-joint underwater robot having the complex movement function according, a depressor, and a mother ship to store data of an underwater state transmitted from the multi-joint underwater robot and to monitor and control a movement direction of the multi-joint underwater robot. The depressor is connected to the mother ship through a primary cable, the multi-joint underwater robot is connected to the depressor through a second cable, and resistance force of the primary cable is applied to the depressor without being transmitted to the multi-joint underwater robot.
US09498882B2 System and method for reinforcing programming education through robotic feedback
A method for toy robot programming, the toy robot including a set of sensors, the method including, at a user device remote from the toy robot: receiving sensor measurements from the toy robot during physical robot manipulation; in response to detecting a programming trigger event, automatically converting the sensor measurements into a series of puppeted programming inputs; and displaying graphical representations of the set of puppeted programming inputs on a programming interface application on the user device.
US09498880B2 Bicycle service rack
An example bicycle service rack includes: a main body extending vertically from a single base; a bicycle mount coupled to the main body, the bicycle mount being configured to hold a bicycle; at least one cable coupled to the main body, the at least one cable being coupled to a bicycle tool; and an air pump coupled to the main body, the air pump being configured to pump air into a tire of the bicycle.
US09498879B1 Quick release cleaning tool
A mechanism by which a user can switch between cleaning tools such as brooms, brushes, and mops while utilizing the same handle. This invention allows the user to reuse the same handle as opposed to having a separate long handle for each cleaning tool. A quick release mechanism that functions by use of a transverse spring and a vertical compression spring allows the user to switch between the cleaning tools quickly and easily.
US09498877B1 Shovel with two integral handles and exterior handle
A shovel with changeable ends and mirrored handle described herein has two circular handle regions. Each circular handle region has a lateral handle, and halfway between the distance from each circular handle region to the other is an exterior handle which rises from the plane of the circular handle regions and can be used to increase torque.
US09498876B2 Collapsible holding arrangement
A holding device for a hand held power tool, in particular, an electric power tool, said holding device comprising an attachment component with at least one attachment element, which can be connected to the power tool; at least one spacer element; as well as a handle with a first handle end and a second handle end. Moreover, the holding device comprises a connecting device, by means of which the attachment component, the spacer element and the handle can be connected to each other.
US09498875B2 Multi-purpose tool
A multi-purpose tool operated by a user for storing, opening, cutting, clamping and holding of articles is provided. The multi-purpose tool includes a first shear, a second shear movably coupled to the first shear at a pivot point and a ratchet extending from each finger grip. Each shear includes a finger grip, cutting edges, tines and gripping tips. Further, the multi-purpose tool includes ratchet extending from respective finger grips. Each ratchet having a plurality of ratchet teeth defined therein, the ratchets extending towards each other. The first cutting edge and the second cutting edge are adapted for extending around the article in a firm grip by engagement of the ratchets in order to clamp the article between the first cutting edge and the second cutting edge.
US09498874B2 Hammer drill
A hammer drill including a cylinder; a piston and a ram mounted within the cylinder; a drive mechanism for converting rotation of a motor into reciprocating movement of the piston; a ram driven by the piston via an air spring; at least two air entry points formed through the wall of the cylinder in different axial positions along the length of the cylinder, each of which are capable of replenishing the air spring; the ram striking a tool in a tool holder; wherein there is further provided a selector mechanism which selectively opens and close the air entry points; characterized in that the selector mechanism opens only one air entry point at any one time during normal use, the selector mechanism closing all other air entry points, each of the air entry point capable of replenishing the air spring during normal use when opened by the selector mechanism.
US09498869B2 Socket wrench
A socket wrench includes a wrench body, a ratchet wheel and a positioning ring. The ratchet wheel has a driving hole and a cylindrical flange extending on one side of the wrench body. The cylindrical flange defines in an outer periphery at least one aperture communicating with the driving hole. The positioning ring is mounted around the cylindrical flange, and has a central bore and at least one protrusion radially protruded from an wall of the central bore of the positioning ring. The protrusion is projected from a wall of the driving hole through the aperture to position a socket.
US09498868B2 Clamping assembly
A clamping system may include one or more clamps configured to be placed in travelling engagement with respective legs of a frame. Workpieces such as wood panels may be clamped against the frame by jaws of the one or more clamps. The one or more clamps may be easily repositionable along the legs of the frame.
US09498857B2 Method of fabricating integrally bladed rotor using surface positioning in relation to surface priority
A method of fabricating an integrally bladed rotor for gas turbine engines according to one aspect includes a step of positioning a blade on a hub in a joining procedure by using a priority surface of the blade as a reference surface. The priority surface is determined in relation to importance of surface functionality of the blades during engine operation.
US09498855B2 Rework system for composite structures
A method and apparatus for reworking a composite structure. A fastener is cooled from a first temperature to a second temperature at which a diameter of a post of the fastener is reduced by a desired amount. The post of the fastener is placed into a channel in a bushing such that a desired interference fit occurs when the fastener is at the first temperature. The bushing with the fastener is positioned in a hole in the composite structure. A gap is present between an outer surface of the bushing and an inner surface of the hole. A gap is also present between an end of the bushing and a second structure.
US09498854B2 Anchor for solar module
An anchor for mounting one or more solar modules to a roof is disclosed. The anchor can comprise a clamp body comprising a central surface and a first arm extending from the central surface. The first arm can have a first clamping face. The clamp body can be sized and shaped to receive one or more webs extending from one or more solar modules, each web having a hem at a distal end. The first arm can comprise a first recess sized and shaped to receive a first hem of a first web of the one or more webs. A clamp member can be configured to clamp the first web against the first clamping face.
US09498850B2 Structural case for aircraft gas turbine engine
The structural case has an annular body having a central axis and including a plurality of boss sections circumferentially interspaced from one another around the axis by a plurality of arcuate panel sections, each panel section having: two parallel arcuate structural flange members being axially interspaced from one another; a sheet metal wall extending between and interconnecting the two flange members; and at least one rib having an edge welded to the sheet-metal wall.
US09498840B2 Welding structural part and welding method of the same
A welding structural part 1 is manufactured by overlapping the surfaces of steel sheets 2, and forming a weld zone by spot welding. The weld zone 3 includes: a weld nugget 4; and a heat affected zone 5 surrounding the weld nugget 4, wherein the hardness in the weld zone increases along an exterior region 6 of the heat affected zone 5 toward the heat affected zone 5, and then decreases along the heat affected zone 5 toward the central region of the weld nugget 4. In the boundary region between the weld nugget 4 and the heat affected zone 5, the weld nugget 4 may have a convex portion 4A bulging into the heat affected zone 5 along the overlapped portion. The steel sheets 2 contain carbon in 0.15 mass % or more.
US09498838B2 System and method of controlling heat input in tandem hot-wire applications
A system and method is provided. The system includes a high intensity energy source to create a molten puddle on a surface of a workpiece and a wire feeder that feeds a wire to the molten puddle via a contact tube. The system also includes a power supply that outputs a first heating current during a first mode of operation and a second heating current during a second mode of operation. The system further includes a controller that initiates the first mode of operation in the power supply to heat the wire to a desired temperature and switches the power supply from the first mode of operation to the second mode of operation to create a micro-arc. The second mode of operation provides at least one of an increased heat input to the molten puddle and an increased agitation of the molten puddle relative to the first mode of operation.
US09498837B2 Vacuum transition for solder bump mold filling
A bond metal injection tool can include a fill head having a sealed chamber for containing a molten bond metal (e.g., solder) and a gas, and a nozzle for directing a flow of the molten bond metal into cavities in a major surface of a mold. A pressure control device can controllably apply pressure within the chamber to eject the bond metal from the nozzle into the cavities. The pressure control device may also controllably reduce a pressure within the chamber to inhibit the bond metal from being ejected from the nozzle, such as when the fill head is being moved onto the mold surface from a parking location or when the fill head is being moved off the mold surface onto a parking location.
US09498833B2 Machine tool for the production of profiles
Machine tool for the production of profiles, such as gearing systems on a workpiece, by means of a rotoncally driven machining tool by generating grinding, profile grinding, generating milling and/or profile milling, having at least one workpiece receiving device, a workpiece machining device and an optional machining tool profiling device. According to the invention, the workpiece machining device is borne by a machine base that has a tangential carriage, a radial carriage, a lifting carriage and a rotational carriage. With this specific construction, the workpiece machining device is guided moveably in all spatial directions with respect to the workpiece receiving device and also, if available, with respect to the machining tool profiling device.
US09498827B2 Arrangement for controlling the process of rotary chip removing machining of a workpiece, and a cutting tool for rotary chip removing machining
An arrangement for controlling the process of rotary chip removing machining of a work piece includes a monitoring system for monitoring the rotary chip removing machining. The monitoring system has at least one surface acoustic wave sensor and at least one first antenna mounted to a cutting tool. At least one second antenna is arranged for wireless communication with the second antenna. Each sensor detects at least one parameter of a group of parameters consisting of strain, temperature and pressure. The sensor and the first antenna transmit the detected at least one parameter to the second antenna in response to an interrogation signal received by the first antenna. A processing unit is connected to the second antenna and transmits the interrogation signal and transmission energy to the first antenna and to the sensor via the second antenna. A control system communicates with the monitoring system to control the machining of the work piece at least partially based on the detected parameter. A cutting tool is provided with the at least one sensor and the at least one first antenna.
US09498824B2 Method of joining sintered parts of different sizes and shapes
A method of joining a plurality of parts to form a unitary body. At least two sintered parts are provided. At least one of the sintered parts has at least one internal cavity. Each of the parts is formed of a hard metal composition of material. The at least two sintered parts are assembled into the shape of a unitary body. Each of the at least two sintered parts has a joining surface and when each joining surface is brought into contact the surfaces form a bonding interface therebetween. The assembled parts are subjected to a vacuum or gas atmosphere, without the application of external pressure, and to a temperature sufficient to fuse the at least two sintered parts together at the bonding interface to form the unitary body.
US09498822B2 Continuous casting equipment
Continuous casting equipment for a flow of liquid metal from a tundish into a mold is provided. The equipment includes a vertical duct disposed upstream of the mold with respect to the direction of travel of the liquid metal. The duct includes from upstream to downstream a refractory ring, a copper tube with an internal diameter D and a submerged entry nozzle. A dome is disposed inside the refractory ring and includes a sloped upper part, the upper part is defined so as to deflect the liquid metal coming from the tundish towards the inner walls of the vertical duct. The diameter D of the copper tube ranges between a minimum diameter equal to Q/3.75 and a maximum diameter equal to Q/1.25, where Q is the nominal liquid metal flow rate of the equipment and is between 200 and 800 kg/min and D is the diameter expressed in mm.
US09498820B2 Apparatus and method for liquid metals treatment
This invention relates to an apparatus (high shear device) and method for treating liquid metals by intensive melt shearing. The apparatus comprises a stator and a rotor with a small gap between them to provide intensive melt shearing for dispersing efficiently and distributing uniformly gas, liquid and solid phases in liquid metals without severe turbulence at the melt surface. The device can be extended to a multistage high shear pump by arranging individual rotor/stator assemblies either concentrically (one in another) or vertically. The device and high shear pump can be readily integrated into existing casting processes. The device is suitable for use in casting processes including high pressure die casting, low pressure die casting, gravity die casting, sand casting, investment casting, direct chill casting, twin roll casting, and any other casting process which requires liquid metal as a feedstock. In addition, the device is particularly suitable for providing conditioned liquid metal for both shape casting and continuous (or semi-continuous) casting of metallic materials, preparing high quality semi-solid slurries, solidification processing of particulate reinforced metal matrix composites, mixing immiscible metallic liquids and degassing of liquid metals prior to any casting processes.
US09498817B1 Barrel assembly for a rivet gun
A barrel assembly for a rivet gun has a barrel, a piston, a rear plug, a fluid tube, a control valve tube and a spring. The barrel has a cavity. The piston is mounted slidably in the cavity and has a rivet ejection passageway. The rear plug is mounted on a rear end of the barrel and has an assembling hole and a sliding passageway. The fluid tube is mounted detachably in the rear end of a head of the piston. The control valve tube is detachably mounted on the rear end of the fluid tube and is mounted slidably in the sliding passageway. With the fluid tube and the control valve tube, the barrel assembly efficiently prevents the high pressure air from continuously leaking out after the pin pulling action is finished.
US09498814B2 Method and device for producing a shaped component
Example methods and devices for producing a shaped component may involve positioning a workpiece having a hollow region and consisting at least partially of steel in a mold of a device. One or more docking punches may secure the workpiece within the mold and serve to introduce a pressurized fluid into the hollow region of the workpiece within the mold. The workpiece may be hot-formed in this process. The present disclosure concerns a variety of methods and devices that may be utilized to counteract a cooling of the workpiece in a region of the docking punch and reduce a temperature difference that may exist between the workpiece and the device.
US09498813B2 Multipoint stretch forming apparatus enabling individual clamping control for manufacturing a curved panel
Provided is a multipoint stretch forming apparatus enabling individual clamping control for manufacturing a curved panel, wherein a plurality of stretching units are positioned at both sides at a lower position of a supporting frame in forward and backward directions, and each of the stretching units is independently and individually controlled. Further, since the distance between the right and left stretching units is adjustable in accordance with the size of punch modules and the size of a curved panel to be formed, the precision formation of both wide and narrow curved panels/shapes is possible. Through this technical constitution, an atypical curved panel is formed more efficiently and the loss of panel material is remarkably reduced.
US09498811B2 Flow formed drum with a retention ring and a substantially burr free tooth profile
A flow formed part includes a first end, a second end, and a side wall extending therebetween. A reinforcing member is disposed around the second end. The side wall has a profile formed along an inner surface of the side wall. The profile is adapted to be substantially burr free after windows are formed in the sidewall. A method of making a flow formed part includes the steps of disposing a preform on a tailstock, providing a plurality of rollers adjacent the tailstock, providing a mandrel having an outer surface including a plurality of alternating channels and protuberances, and causing the rollers to press the preform against the outer surface of the mandrel.
US09498807B2 Heat treatment method, heat-treating furnace, and heat treatment system
A work is subjected to a heat treatment in a heat-treating furnace. First, the work is carried into the heat-treating furnace. The work in the heat-treating furnace is immersed in a heat source solvent. In the heat-treating furnace, a superheated steam atmosphere is formed. The work is exposed in the heat-treating furnace under the superheated steam atmosphere. Then, the work is carried out of the heat-treating furnace.
US09498804B2 Pipeline pigs
A scraper pig for cleaning tubes and pipelines comprising a flexible core provided with a casing in which scraper studs are embedded in a manner whereby they protrude sufficiently to perform a cleaning action when they are propelled through the tube. A method for the manufacture of the pig and the design of the stud is also provided.
US09498796B2 Method and apparatus for monitoring wear of and repairing shaker screens
The invention is an apparatus for cleansing and monitoring wear of screen cloths (1) comprising: a) a feeding device (100) for used or contaminated screen cloths (1) to b) a cleansing unit (4) arranged for receiving and cleansing said screen cloth (1), c) a preparation unit (140) arranged for preparing said screen cloth (1) for optical inspection in d) an optical inspection station (120) arranged to identify one or more damaged portions (6) of said screen cloth (1) and with a registering device for registering positions (7) for said damaged portions (6), e) a measuring device (62) for measuring and registering an extent of said one or more damaged portions (6) extent and degree of damage, f) a repair unit (70) arranged for mending one or more of said damaged portions (6), g) a feeding out unit (200) for feeding out said repaired screen cloth (1).
US09498792B2 Roof adhesive distribution apparatus
A distribution apparatus for applying a one or two-part adhesive to a substrate includes a wand with a plurality of openings through which the adhesive is dispensed. An extension is connected in fluid communication to the wand. The extension directs a flow of adhesive to the wand.
US09498789B2 Nebulizer and nebulizer kit
A nebulizer kit includes a case body having a compressed air introduction tube in an upper end portion of which is a nozzle hole that expels compressed air, a suction channel formation member forming a suction channel for sucking liquid toward the upper end portion and forming an atomizing area in an exit region of the hole, and a flow channel formation member having an aerosol discharge port. The suction channel has first and second suction channels respectively extending upward along an outer circumferential surface of the tube and from the suction channel toward the hole at a leading end area of the tube and has a liquid suction port that expels the liquid. A particle segregating portion having a blade portion, whose orientation to the atomizing area is adjustable, is between the atomizing area and the port. The suction channel formation member is fixed to the case body.
US09498786B2 Dry flue gas desulfurization system with dual feed atomizer liquid distributor
An atomizer system 160 for use in a spray dry absorber 130, the atomizer system 160 includes a support member 161, an atomizing disc 162 rotatably coupled to the support member 161, a first feed line 163 for delivery of a reagent slurry 163a to a delivery area 165 and a second feed line 164 for delivery of a dilution liquid 164a to the delivery area 165. The delivery area 165 is positioned within the atomizer system 160 to reduce scale buildup generated by interaction of the reagent slurry 163a and the dilution liquid 164a.
US09498783B2 Passively energized field wire for electrically enhanced air filtration system
An air filtration system includes a frame directing an airflow through the air filtration system and a power supply. An ionization array is located in the frame across the airflow and connected to the power supply. The power supply provides a first voltage to the ionization array. A field wire is located in the frame downstream from the ionization array and is energized to a second voltage only by an electrical energy discharge from the ionization array. A method of operating an electrically enhanced air filtration system includes energizing an ionization array, located across an airflow through the air filtration system, to a first voltage via electrical power supplied by a power supply. Electrical energy is discharged from the ionization array into the airflow. A field wire downstream of the ionization array is energized to a second voltage only by the discharge of electrical energy from the ionization array.
US09498782B2 Method for classifying articles and method for fabricating a magnetocalorically active working component for magnetic heat exchange
A method for classifying articles comprising magnetocalorically active material according to magnetic transition temperature comprises providing a source of articles to be classified, the source comprising articles comprising magnetocalorically active materials having differing magnetic transition temperatures, sequentially applying a magnetic field at differing temperatures to the source, the magnetic field being sufficient to exert a magnetic force on the source that is greater than the inertia of a fraction of the articles causing the fraction of the articles to move and produce an article fraction, and collecting the article fraction at each temperature to provide a plurality of separate article fractions of differing magnetic transition temperature, thus classifying the articles comprising magnetocalorically active material according to magnetic transition temperature.
US09498779B2 Method for regulating the roll gap pressure of a roller press
A method for regulating the roll gap pressure of a roller press and a corresponding roller press. The roll gap pressure is regulated dependent on at least one oscillating movement that is measured on the roller press. This has the advantage that the roller press can always be operated at the maximum roller press efficiency without the roller press reaching the overload range.
US09498774B2 Composite body in which first metal-containing particles and second metal-containing particles are supported on carbon material or connected by carbon material, and method for producing same
The present invention relates to a composite body in which first metal-containing particles and second metal-containing particles are supported on a carbon material or connected by a carbon material, and a method for producing the same. The above composite body can, if the first metal-containing particles exhibit a catalytic activity, be applied as a reaction catalyst and can also be used in various fields such as the manufacture of the adsorbent or the separation membrane.
US09498773B2 Catalyst system for olefin oligomerization, and method for olefin oligomerization using the same
The present invention relates to a compound represented by Chemical Formula 1, a catalyst system for olefin oligomerization comprising the same, and a method of olefin oligomerization using the same.
US09498771B2 Catalyst for exhaust gas purification, and method for producing same
To provide an exhaust gas catalyst using a fired aluminum phosphate body with more excellent performance, and a method for producing it. (1) An exhaust gas purification catalyst including at least one platinum-group metal selected from the group consisting of Pt, Rh and Pd having a mean particle diameter of between 0.50 nm and 2.0 nm, supported on a tridymite-type fired aluminum phosphate body. (2) A method for producing an exhaust gas purification catalyst, including the steps of: firing aluminum phosphate obtained from an aqueous solution prepared to a pH of 3.5 to 4.5, at a temperature of between 1000° C. and 1200° C. for 2 hours or longer, to obtain a fired aluminum phosphate body, and supporting at least one type of platinum-group metal selected from the group consisting of Pt, Rh and Pd on the fired aluminum phosphate body.
US09498770B2 Ce-based composite oxide catalyst, preparation method and application thereof
Disclosed is a Ce-based composite oxide catalyst for selective catalytic reducing nitrogen oxides with ammonia, which comprises Ce oxide and at least one oxide of transition metal except Ce. The Ce-based composite oxide catalyst is prepared by a simple method which uses non-toxic and harmless raw materials, and it has the following advantages: high catalytic activity, and excellent selectivity for generating nitrogen etc. The catalyst can be applied in catalytic cleaning plant for nitrogen oxides from mobile and stationary sources.
US09498767B2 Systems and methods for providing ZPGM perovskite catalyst for diesel oxidation applications
Diesel oxidation ZPGM catalyst systems using Y1-x AgxMnO3 perovskite are disclosed. The ZPGM catalyst system compositions may include Y1-x AgxMnO3 perovskite in impregnation component and at least one carrier material oxide in washcoat. The ZPGM catalyst system compositions may also include Y1-x AgxMnO3 perovskite co-precipitated in a carrier material oxide as washcoat. The catalyst activity is measured with an inlet gas mixture containing diesel exhaust composition and characterized according to performance in NO oxidation, NO2 production, NO storage capability and diesel oxidation applications.
US09498765B2 Hydrogen or oxygen electrochemical pumping catalytic membrane reactor and its applications
The disclosed subject matter includes a new type of chemical reactor, described as hydrogen or oxygen electrochemical pumping catalytic membrane reactor. This new type of reactor is suitable for increasing the selectivity and the conversion rate of dehydrogenation, hydrogenation, deoxidation and oxidation reactions and namely in the direct amination reaction of hydrocarbons. This reactor can be used for the production of several chemical compounds, such as the direct amination of hydrocarbons and in particular for the synthesis of aniline from benzene. The disclosed subject matter includes a device and process wherein hydrogen is removed by electrochemical pumping of the hydrogen formed or by oxygen pumping so, as hydrogen is formed, it is oxidized. This new reactor exhibits benzene to aniline conversion higher than 40%.
US09498764B2 Synthesis gas and nanocarbon production method and production system
A synthesis gas and nanocarbon production method has a lower hydrocarbon decomposition step for decomposing lower hydrocarbon to produce hydrogen and nanocarbon, a carbon dioxide reduction step for reacting a part of the nanocarbon produced with carbon dioxide to produce carbon monoxide, and a mixing step for mixing the hydrogen and carbon monoxide produced in a predetermined ratio, thereby nanocarbon and a synthesis gas having a desired gas ratio can be simultaneously produced easily.
US09498762B2 System and process for producing an oxirane
Embodiments of the present disclosure are directed to a system and a process for producing an oxirane. For the various embodiments, the system and process of the present disclosure includes: a reaction vessel having a reaction mixture of an olefin, a peroxide compound, a solvent mixture with an alcohol and a non-reactive co-solvent, a solid phase, and reaction products of the reaction mixture, where the reaction products include an oxirane; a separation vessel coupled to the reaction vessel, where an effluent of the reaction mixture and reaction products from the reaction vessel separates in the separation vessel into a liquid aqueous phase and a liquid organic phase; and an extraction vessel coupled to an outlet of the separation vessel, where the liquid aqueous phase taken from the outlet of the separation vessel mixes with an extraction solvent to extract oxirane from the aqueous phase.
US09498760B2 Stable nanoparticulate suspension and method for production
The invention relates to a stable, highly concentrated, aqueous suspension of nanoparticles, particularly of titanium dioxide particles, a method for production, and use of the suspension, e.g. for coating or impregnation, or as an additive in organic or inorganic matrices. The suspension contains a first dispersant based on a polymeric alkoxylate and a second dispersant selected from the group of amino alcohols. The suspension is preferably characterized by the fact that its stability is preserved even during and after vigorous dispersion in an attrition mill and no increase in viscosity occurs. In a preferred embodiment, the viscosity declines by up to 10 to 50% as a function of the milling time. In a further embodiment, the suspension can be dried and subsequently redispersed, without the state of dispersion deteriorating.
US09498758B2 Dilution apparatus
A dilution apparatus includes a container having an adjustable float-operated make-up valve wherein the make-up valve has an inlet end connected to a water supply tube and an outlet end connected to a fill tube inside the container. The make-up valve is connected to a float disposed inside the container. The water supply tube is connected to a reservoir that contains a concentrate. The water flow through the water supply tube siphons the concentrate, into the water stream and through the make-up valve to form a first dilution. A proportioner is connected to a water supply and to the bottom of the container. The water flow through the proportioner siphons the first dilution into the proportioner, thereby mixing the first dilution with water to form a final product having a predetermined dilution ratio.
US09498754B2 Method for improving rejection of reverse osmosis membrane, treatment agent for improving rejection, and reverse osmosis membrane
A method capable of effectively improving a rejection of a reverse osmosis membrane without remarkably reducing a permeation flux, even if the membrane is seriously degraded. An aqueous solution containing a first organic compound having a molecular weight of less than 200, a second organic compound having a molecular weight of 200 to less than 500, and a third organic compound having a molecular weight of 500 or more is passed through the reverse osmosis membrane. The first organic compound is preferably an amino acid or an amino acid derivative. The total concentration of the first organic compound and the second organic compound and the concentration of the third organic compound are each preferably 1 to 500 mg/L.
US09498742B2 Filtration material for filters, and filter cartridge
The present invention relates to a filter material including a sheet-like laminate which includes an ultrafine fiber aggregate layer formed of an aggregate of ultrafine fibers produced by an electrospinning method having an average fiber diameter of not less than 10 nm and not more than 1000 nm, and a base material formed of a nonwoven fabric or a woven fabric constituted from fibers having an average fiber diameter of 1 μm or more, said filter material satisfying all of a plurality of specific requirements, having a capability of collecting or separating μm-order microfine particles with a high accuracy and exhibiting a less pressure loss and a long filtering life, as well as a filter cartridge using the filter material.
US09498741B2 Filter assembly
An assembly including a first filter element; and a filter element assembly connected to the first filter element. The filter element assembly includes a second filter element located between a first plate and a second plate. The second plate includes a liquid outlet into a center open area of the first filter element. The first and second plates are directly fixedly connected to each other to retain the second filter element therebetween. The second plate is located at an end of the first filter element.
US09498735B2 Polygonal tiles for two-dimensional and three-dimensional symmetry structures
A variety of sets of interconnecting plane tiles having shapes, patterns on the faces of some of the tiles and interconnecting elements to be able to construct all 17 plane periodic patterns, the five Platonic solids and the thirteen Archimedean solids are described. The tiles include connectors that enable constructing plane patterns as well as three-dimensional solids.
US09498733B2 Balloon with lighting/sounding device
A balloon with a lighting/sounding device includes a balloon body and a lighting/sounding device secured onto a wall of the balloon body, wherein the lighting/sounding device is secured onto the balloon wall via an external cover. The lighting/sounding device is secured via the external cover, which facilitates setting and installation of the lighting/sounding device and simplifies a configuration structure thereof so as to reduce manufacturing costs, and such a structure will not affect the inflation and use of the balloon but provides more convenient decoration and entertainment.
US09498732B2 Model railway aesthetic insert
An aesthetic insert adapted to be received between a wheel-bearing rail and the center rail of extant model railroad track, and in its installed position at least partially covers or hides the side of the center rail, camouflaging it and rendering it less noticeable. The installed insert superposes portions of and simulates the presence and/or appearance of a crosstie surface. The insert may be a separately installable, individual element, or a plurality of interconnected individual elements installable as a group and interconnected by one or more connecting members.
US09498730B2 Yoyo capable to be manually accelerated when held by hands
A yoyo capable to be manually accelerated when held by hands comprising two spinning bodies (1), a button (2) and a side cap (3) mounted at center positions of outer sides of the two spinning bodies (1) respectively, a manual acceleration mechanism provided inside the two spinning bodies (1) and connecting the two spinning bodies (1) as a whole, and a bearing (4) disposed between the two spinning bodies (1) for winding a yoyo string; two ends of the manual acceleration mechanism are connected with the spinning bodies (1); by pressing the button (2), the manual acceleration mechanism drives the spinning bodies (10) to spin. The yoyo has a wider range of utility satisfying the playing needs of kids and children and at the same time increasing the ways of playing the yoyo and thus the fun in playing the yoyo. Also, the yoyo allows players to create their own ways of playing the yoyo.
US09498726B2 Method and systems for marketing and selling fantasy sports and/or stock market teams
A method and systems are disclosed for marketing fantasy sports and/or stock market teams to potential investors, where an investor in a fantasy team shares in the winnings of that team. An owner of a fantasy sports team or a fantasy stock market portfolio offers his/her team up for sale or investment. The team can be sold in its entirety, or only a partial stake in the team can be sold, at the discretion of the owner. Potential investors view teams which are up for sale or investment, research team background and performance, and if desired, make an offer to buy a share of a team. Offers to sell and buy can be handled as either fixed price transactions or as auction-style bidding. Team owners split profits with investors according to ownership percentage. Investor pools and partnerships are possible, and many other features for facilitating investment transactions are disclosed.
US09498725B2 Method and apparatus to play cards
The present invention relates to a method for controlling a network (100) of equipment (10a, 10b, 11) for the game of cards. The network includes a server for controlling the game (10b, 11) and at least one piece of playing equipment (10a), the server and the piece of playing equipment being able to communicate data between them, each piece of playing equipment (10a) including display means (20). The method comprises the steps of: identifying a portion (R) of the totality (T) of the playing cards which is able to be displayed on the display means (20), the portion (R) of cards displayed being the same in all the pieces of playing equipment (10a); determining the number of cards assigned (Q) to each player using a piece of playing equipment (10a) in order to play a hand at the game of cards; generating at the side of the server (10b, 11) a vector vetcar having a dimension which is equal to or greater than the total number of cards (T), there being associated with each a element vetcar(i) of the vector a card of the totality of cards (T); generating a plurality of elements in a number equal to the portion (R) of cards and subdividing the plurality of elements into a plurality of m subgroups sottogrup, each of those elements in each subgroup being unambiguously identified by at least one alphanumeric character; displaying on the display means (20) in each piece of playing equipment the elements subdivided into the subgroups; selecting in the piece of playing equipment (10a) in a first selection an element from the n forming a subgroup of the plurality and sending to the server (10b) a piece of data representing the alphanumeric character identifying the element or alternatively generating in the server (10b, 11) an alphanumeric character which unambiguously determines an element in one of the subgroups and sending a piece of data representing the alphanumeric character to the piece of playing equipment so as to select an element from a subgroup of the plurality; sending the vector vetcar from the server (10b) to all the pieces of playing equipment (10a) present in the network (100); associating with each element of the subgroups a card of the vector vetcar, the same card is associated with the same element identified by the same alphanumeric character in each piece of playing equipment (10a); the element selected in the first selection being associated with a card which forms part of the cards (Q) in the possession of the player in a hand of the game.
US09498724B2 Method of and system for conducting multiple contests of skill with a single performance
A method of and system for conducting multiple competitions of skill for a single performance are described herein. User generated competition groups and system generated competition groups allow users to participate in multiple competitions at once based on answering the same questions or making the same selections related to a single event. The users are informed of each competition either via email, text message or when logging into the network via a website. The users select which competitions groups to join. After joining the desired groups, the users then make their selections related to the event which are transmitted to the network where results are tabulated and transmitted back to the users. The results are separated based on each competition group, so that users can continually know where they stand in each separate competition. With multiple competition groups, users are able to have varying success from the same performance in multiple competitions.
US09498723B2 Server device, user device, method for controlling server device, recording medium, and system
Provided is a server device, etc., capable of enhancing flexibility of a reward winning game and maintaining a user's interest in the game. The server device manages rewards to be given to a user, and includes a storage unit for storing a package as a set of data concerning rewards to be given to the user and a modified package as a set of data concerning rewards used to update the package, a communication unit for communicating with a user device of the user, and a package updating unit for updating the package by modifying the data concerning the rewards included in the package by using the data concerning the rewards included in the modified package when a package update request is received from the user device.
US09498716B2 Video game device and storage medium storing video game program
A video game device successively obtains game data, which changes according to the state of the input device and is used in the game process. The video game device stores game data obtained at a point in time when the game process is paused. The video game device successively compares current game data with the stored game data, after starting to accept cancellation of the pause. The pause is canceled to resume the game process when a difference between a value of the current game data and a value of the game data stored in the storage means becomes smaller than a predetermined reference.
US09498711B2 Multi-player, multi-screens, electronic gaming platform and system
A multi-player, multi-screens, electronic gaming platform and system is disclosed, having a game board having a main display screen for displaying a portion of the game layout that is shared by the plurality of players, and a plurality of personal game terminals, each personal game terminal assigned to a respective player and having an auxiliary display screen for displaying a portion of the game layout that is associated with the respective player. Communication between the main display and the terminals, and among terminals directly is enabled. Also enabled is seamless transfer of objects between the display screens as triggered by a game step or interactive inputs. Coded rules associated with the transferred objects can indicate where on the screen the digitized game object should appear, at what size should it be displayed, special animation or audio that should accompany the transfer of the digitized game object, etc.
US09498708B2 Systems and methods for processing positional and sound input of user input to a touch panel
A game apparatus detects an input position, on an input plane, at which an input operation has been performed. The game apparatus also detects an operation sound that occurs due to the input operation performed on the input plane. The game apparatus evaluates the detected operation sound, and obtains a result of the evaluation (e.g., volume of the operation sound). The game apparatus performs game processing by using the detected input position and the result of the evaluation. This enables the game apparatus to perform more complex processing by using a touch operation as input information, and allows a player to provide more complex instructions based on the touch operation.
US09498705B2 Video game system having novel input devices
A video game system includes an input device, where the input device has at least one physiological sensing device for determining at least one physiological state of a user. The input device further has at least one motion sensing device for determining the motion and/or position of the input device and/or the user. The video game system further comprises a processor for using the physiological state and the motion and/or position of the input device and/or user to control game play.
US09498700B2 Recreational power and stabilizing apparatus
A watersports paddle includes an elongated handle body having a first material, a biased member having a second material more flexible than the first material such that the biased member is more flexible than the elongated handle body, and a paddle blade coupled to the biased member opposite the elongated handle body. The biased member deforms when a force is applied to the biased member with the elongated handle body by pulling the paddle blade through water and reforms when the force is not applied to the biased member by the elongated handle body to store and release energy during use of the watersports paddle. The biased member may be a substantially planar leaf spring or a bowed leaf spring.
US09498695B2 Device and method to precisely isolate and minimize direction errors for short putts
A device for practicing putting of a golf ball includes: an elongate base with opposed first and second ends and an upper surface; an elongate rail with an upper surface and opposed first and second ends, the rail mounted to the base such that the upper surface of the rail is positioned above and generally parallel with the upper surface of the base; a locating feature positioned adjacent the first end of the rail, the locating feature configured to provide a resting place for a golf ball; and a target area positioned near the second end of the base panel located adjacent the second end of the rail. Such a device can provide immediate and accurate feedback on putting errors committed by the user.
US09498694B2 System and method for creating content for an event using a social network
A system and method for creating content such as artificial reality (AR) messages at an event, particularly among members on a social network, thereby enhancing and expanding the event experience. Typically, a participant shares an event with spectators, such as friends or a subset of friends in the participant's social network. The AR message may include geo-referenced artificial reality words, products or symbols and appear in a perspective view of the event to the participant or spectators. In addition to creating an active gallery for an event, messages, audio and video can be exchanged among participants and spectators, and virtual goods, money, bets, applause, other feedback, and donations exchanged.
US09498691B2 Training apparatus for athletes and others
A training apparatus particularly suited for ice skaters. The training apparatus includes a cover, typically formed as shorts sized to be worn over traditional hockey pants or a hockey girdle, and one or more connectors. The connectors are attached to the cover in fixed positions around the upper leg and buttocks of the user of the training apparatus, and slidably and releasably receive through looped parts at least one elongate, flexible, elastic resistive member to provide resistance against the motion of a user while engaging in physical activities, such as skating. The connectors are mounted on both the front and back of the cover and include upper connectors mounted on an upper tubular section of the cover and lower connectors mounted on the front of leg sections of the cover.
US09498682B2 RFID embedded within inner core of a multi-core golf ball
A multi-core golf ball with an RFID tag embedded thereon is described herein. The multi-core golf ball includes a spherical inner core, an RFID tag, an outer core, and a dimpled cover. The RFID tag is positioned to interface with the spherical inner core. The outer core is configured to encapsulate the spherical inner core and the RFID tag. The dimpled cover is further configured to encase the spherical inner core, the RFID tag and the outer core.
US09498681B2 Golf ball and method for manufacturing the same
An object of the present invention is to provide a golf ball comprising a core formed from a rubber composition containing (d) a carboxylic acid and/or a salt thereof and traveling a great flight distance on driver shots. The present invention provides a golf ball comprising a spherical core and at least one cover layer covering the spherical core, wherein the spherical core is formed from a rubber composition containing (a) a base rubber, (b) an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms and/or a metal salt thereof as a co-crosslinking agent, (c) a crosslinking initiator, (d) a carboxylic acid and/or a salt thereof and two or more kinds of (e) organic sulfur compounds, provided that the rubber composition further contains (f) a metal compound in case of containing only (b) the α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms as the co-crosslinking agent.
US09498679B2 Adjustable fitness arena
Aspects of this disclosure relate to systems and methods for conducting sport-specific activities. Illustrated systems may be adjustable to permit a performance of different sport-specific activities. Further aspects relate to using sensor data to evaluate a user's performance and determine sport-specific fitness parameters. Various fitness parameters may measure reactive agility and/or the physiological state of the user, such as when in an exhausted state. Illustrated systems may have structures with an output device and a sensor. The structure may include a vertically-arranged planar surface to form a wall. Several structures may be configured to form a boundary. The boundary may be automatically adjustable, for example, depending on one or more specific fitness routines to be implemented. Calculated fitness parameters may be visually mapped on the structures of the system.
US09498678B2 Ball tracker camera
Systems and methods for ball tracking are provided. An identification processor may be coupled to a ball and may generate wireless signals as the ball is moving. At least three triangulation antennas may be distributed at different locations within an event venue. Such triangulation antennas may receive the wireless signals from the identification processor in real-time. Such signals may be used to determine a real-time location of the ball within the event venue. A controller may then adjust a gimbal to point the camera at the determined real-time location of the ball.
US09498675B2 Neck therapy exercise device and method
Disclosed is a neck therapy exercise apparatus, comprising a helmet having a weighted flexible rod which may be either permanently or detachably affixed to the top exterior center of the helmet. The flexible rod consists of a first end which may have a connector enabling the attachment of various sized weights to the first end, and a second end, affixed to the helmet. The helmet is custom-sized to a user's head and securely fastened to the head. Therapeutic exercise is accomplished by the user, while wearing the helmet, and weighted flexible rod, slowly rotating his/her head 360 degrees in a generally horizontal plane in either a clockwise or counter-clockwise direction. In different embodiments, the user may replace the weights at the end of flexible rod with increasingly heavier weights as strength is gained during the exercises.
US09498672B1 Elliptical exercise device with moving control tracks
An elliptical exercise device has a frame and guide link pivotally attached thereto. A foot support link is pivotally connected to a lower attachment point of each guide link so that when the guide links pivot relative to the frame, foot receiving areas of the foot support links move in a path of travel having a horizontal component of motion. Vertical control tracks are pivotally connected to the frame and support the foot support links. A vertical drive is coupled to the forward portion of the frame and vertical control elements connect the vertical drive to the vertical control tracks. A horizontal drive and horizontal control links control pivoting of the guide links.
US09498669B2 Resistance exercise trainer having portable hand-held weights
The soft weight strength trainer includes a selectively fillable pouch with a strap positioned so that a person can fit a hand or foot in-between the strap and the fillable pouch. The soft weight strength trainer can be utilized in a variety of exercises that strengthen various muscle groups. None of the exercises that are performed with the soft weight strength trainer require a close fisted grip, which makes the soft weight strength trainer ideal for use by a person with reduced hand strength due to age or injury. Additionally, the soft weight strength trainer will not cause damage or injury if inadvertently dropped due to its non-rigid construction.
US09498655B2 Safety and descender device
It is described a belay, of static or dynamic type, and descender, of self-blocking type and not, device for securing one or more ropes comprising a main body composed of at least two or more flat plates constrained one to another according to planes preferably parallel, or slightly tilted, by a plurality of spacer pins. The rope/s is/are inserted inside the body of the device which further comprises a first karabiner hooked to the main body by passing through an opening in the device body. The karabiner is movable in the opening between an unlocking position of the rope, that is the usual use condition, and an emergency position wherein the rope is blocked, and vice versa. The device further comprises a hole passing through the device body allowing the hooking of the first karabiner removed from the opening or of a second karabiner around which the rope/s is/are passed, and further means for constraining the device body to a fixed hooking point, which comprise at least one through hole inside which a further respective karabiner is hooked.
US09498654B2 Sebum absorption compositions
Sebum absorption compositions are disclosed which include (a) 1% to 20% by weight of the composition of a sebum absorption ingredient; and (b) 20% to 99% by weight of the composition of a volatile solvent.
US09498653B2 Sunscreen cosmetic composition containing ultraviolet absorber
A sunscreen cosmetic composition contains an ultraviolet absorber composed of a triazine compound (a) represented by the general formula (1) below and a triazine compound (b) represented by chemical formula (2) below. In the general formula (I) below, R1 represents a linear or branched C1-12 alkyl group, a C3-8 cycloalkyl group, a C3-8 alkenyl group, a C6-18 aryl group, a C7-18 alkylaryl group, or a C7-18 arylalkyl group (with the proviso that these groups may be substituted by a hydroxy group, a halogen atom or a C1-12 alkyl or alkoxy group, and may be interrupted by an oxygen atom, a sulfur atom, a carbonyl group, an ester group, an amide group or an imino group, and further that the substitution and the interruption may be combined); and R2 represents a C1-8 alkyl group, or a C3-8 alkenyl group.
US09498652B2 Composition, process for preparation and method of use
Depilatory compositions comprising a depilatory agent, fatty alcohol and VP/hexadecene copolymer provide improved resistance to rinsing of the compositions from the skin. The compositions provide for a method-of depilation in wet conditions using a tool to apply and remove the compositions.
US09498650B2 Method of treatment with combination ultrasound-phototherapy transducer
A soundhead of a treatment device is provided that enables a volume of tissue located beneath the soundhead to simultaneously receive ultrasound and light stimulation. According to one embodiment, the soundhead includes an ultrasound transducer, a light source, and a faceplate extending across a face of the transducer for providing a tissue contacting and ultrasound energy coupling surface of the soundhead. The faceplate is transparent or translucent to the light generated by the light source. Alternate embodiments including externally mounted light sources are also disclosed.
US09498648B2 3D imaging method for accurate in-plane tracking of lesion to be treated using MRgRT
When monitoring a position of organ(s) at risk (OAR) near a target volume to be irradiated, a LINAC radiation beam source position is identified around a target volume, and a plane perpendicular to a radiation beam is identified. A first phase encoding direction within the plane is assigned, and a second phase encoding direction perpendicular to the first phase encoding direction is assigned. A read-out direction parallel to the radiation beam is assigned, and an MR image of the target volume and any OAR(s) is generated. The position of the target volume relative to the radiation beam is determined and a collimator between the LINAC source and the volume of interest and target volume is controlled to maintain the radiation beam on the target volume and away from any OAR(s) based on the determined position of the target volume.
US09498647B2 Fiducial marker system for subject movement compensation during medical treatment
A system is provided for subject movement compensation during a medical procedure. The system uses passive radiofrequency identification tags associated with a subject, and at least one active RFID reader is positioned to interrogate the position of at least three such passive radiofrequency identification tags so as to triangulate the geometric position of a subject body tissue. The reader generates an output signal corresponding to a distance between said reader and a tag. A microprocessor calculates a displacement of a tag relative to the reader from said output signal to yield a value corresponding to subject movement. A medical device operates in synchronicity with the calculation corresponding to subject movement to compensate for subject movement during a treatment process in essentially real time. A process for subject movement compensation during a medical procedure is also provided.
US09498643B2 Systems and methods for interior energy-activation from an exterior source
A method and a system for producing a change in a medium. The method places in a vicinity of the medium at least one energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
US09498639B2 Immersive, flux-guided, micro-coil apparatus and method
A PEMF web using immersive, flux-guided, micro-coils to direct intense, deeply penetrating, magnetic flux into a subject from each micro-coil capable of pointing in an arbitrary direction. Micro-coils are spooled around iron cores, insulated properly, and soldered to connecting wires, all embedded in a polymeric resin, such as cold-cured silicone resin. Nodes protect, enclose, insulate electrically, and otherwise protect the micro-coils. Connectors between nodes provide mechanical stability against breaking of wires, while permitting folding, bending, buckling, and otherwise deflecting to position the nodes as desired with three degrees of freedom.
US09498636B2 Implantable head located radiofrequency coupled neurostimulation system for head pain
A method is provided for controlling power delivery from an external power transfer system (EPTS) to at least one implantable neurostimulator system (INS). The method comprises driving a first transmit coil within the EPTS using a transmit coil driver circuit, receiving, using a receive coil, power transferred from the first transmit coil, coupling the received power to a regulator circuit, monitoring the regulator circuit, communicating a message to the EPTS using a back telemetry circuit, receiving the message, and adjusting the transmit coil driver circuit.
US09498633B2 Percutaneous tibial nerve stimulator
A method for treating incontinence includes positioning a transcutaneous electrode on skin of a patient adjacent a stimulation site; inserting a leading end of a percutaneous needle electrode through the skin adjacent the stimulation site, the percutaneous needle electrode including a lead wire disposed opposite the leading end; securing a neurostimulator unit to the transcutaneous electrode such that the neurostimulator unit is electrically coupled to the transcutaneous electrode with no lead wire disposed between the neurostimulator unit and the transcutaneous electrode, the neurostimulator unit including a pulse generator; connecting the lead wire of the percutaneous needle electrode to the neurostimulator unit for electrically coupling the needle electrode to the neurostimulator unit; and activating the pulse generator such that current pulses traverse the stimulation site by passing between the transcutaneous electrode pad and the percutaneous needle electrode.
US09498632B2 Receiver and digital demodulation circuitry for an external controller useable in an implantable medical device system
Receiver and digital demodulation circuitry for an external controller for communicating with an implantable medical device (IMD) is disclosed. A Digital Signal Processor (DSP) is used to sample received analog data transmitted from the IMD at a lower rate than would otherwise be required for the frequency components in the transmitted data by the Nyquist sampling criteria. To allow for this reduced sampling rate, the incoming data is shifted to a lower intermediate frequency using a switching circuit. The switching circuit receives a clock signal, which is preferably but not necessarily the same clock signal used by the DSP to sample the data. The switching circuit multiplies the received data with the clock signal to produce lower intermediate frequencies, which can then be adequately sampled at the DSP at the reduced sampling rate per the Nyquist sampling criteria.
US09498626B2 Automatic selection of reduction or enhancement of transient sounds
A system and method of generating electrode stimulation signals for electrode contacts in an electrode array associated with a hearing implant is presented. An input audio signal is processed to generate a plurality of band pass channel signals each representing an associated band of audio frequencies. A stationary noise reduction is applied so as to provide a stationary noise reduced channel envelope from each channel signal. A transient in one or more of the channel envelopes is detected. The channel envelopes are modified as a function of whether the transient is transient noise or transient speech, so as to form transient modified envelope. The transient modified envelopes are used to generate electrode stimulation signals to the electrode contacts.
US09498624B2 Stimulation of the urinary system
Apparatus and methods are provided, including a bladder stimulator that includes an elongate element adapted to pass through a urethra or adapted to pass through another opening in the bladder, an expandable body coupled to said elongate element, and an array of one or more stimulator contacts coupled to the expandable body, the array including at least one contact adapted to contact a portion of a bladder of a subject when the expandable body is inserted in the bladder and expanded. A controller stimulates the portion of the bladder by driving a pulse into the bladder via the contact, the pulse having a frequency of 5 Hz-1 kHz. Other applications are also described.
US09498622B2 Programming techniques for peripheral nerve field stimulation
Peripheral nerve field stimulation (PNFS) delivered by medical device to a patient may be programmed by specifying one or more characteristics of a stimulation field generated by the IMD to provide the PNFS. The characteristics of the stimulation field may include, for example, a direction of stimulation within the field, a breadth of the stimulation field, a focus of stimulation within the stimulation field, a depth of the stimulation field relative to a reference point, such as the epidermis of the patient, or a nerve fiber diameter selection.
US09498621B2 Separated-interface nerve electrode
Example ionic coupling electrodes are described. One example ionic conducting electrode includes a first portion that can be coupled to a single phase current source. The first portion carries current flow via electrons. The electrode includes a second portion to apply a current to a nerve tissue. The second portion carries current flow via ions. The second portion is positioned between the nerve tissue and the first portion to prevent the first portion from touching the nerve tissue. The current applied to the nerve tissue is produced in the second portion in response to a current that is present in the first portion. The current present in the first portion is provided from a single phase current source. The electrode may be used in applications including, but not limited to, nerve block applications and nerve stimulation applications.
US09498616B2 Irreversibly closable flow control clamp
A flow control clamp having a first member and a second member movable from a first open position to a second irreversibly closed position wherein flow through a tube associated with the clamp is irreversibly prevented and cannot be restored. Systems and methods using such clamps are also disclosed.
US09498614B2 Needleless valve infection prevention and pre-opening device
A disinfecting and pre-opening device is disclosed for use with a female needleless connector. The disinfecting and pre-opening device includes a housing comprising a chamber having a distal opening and configured to fit over the female needleless connector, and an elongated finger attached to the housing and disposed within the chamber such that the elongated finger opens the fluid path through the female needleless connector when the distal opening of the disinfecting and pre-opening device is placed proximally adjacent to the septum and the disinfecting and pre-opening device is advanced in the distal direction.
US09498612B2 Method of treating infections, diseases or disorders of nail unit
Methods for the subungual treatment of diseases or disorders of the nail unit including infections, especially fungal infections, and nail psoriasis involving the toenails and fingernails are described. The methods provide a technique for placement of a drug-containing composition subungually with reduced risk of hematoma formation and improved patient comfort.
US09498608B2 Implantable fluid delivery apparatus with micro-valve
A fluid delivery system includes an implantable fluid source, a first catheter in fluid communication with the implantable fluid source, and an implantable micro-valve in fluid communication with the first catheter, the micro-valve configured to be located within a round window or to be secured to a promontory bone of a cochlea.
US09498603B2 Guidewire with adjustable stiffness
A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.
US09498602B2 Guided intravascular catheter sheath having bi-directional steering assembly
A steerable intravascular catheter is disclosed which includes an elongated sheath having a tubular body wall defining a central lumen and a deflectable distal end portion, a pair of laterally opposed elongated pull wires extending through the tubular body wall of the sheath and terminating within the distal end portion thereof, and a handle assembly having a longitudinal axis and operatively associated with a proximal end portion of the sheath, the handle assembly including an rotatable control knob for controlling bi-directional deflection of the distal end portion of the sheath, wherein bi-directional angular rotation of the control knob about the longitudinal axis of the handle assembly effectuates corresponding reciprocal axial movement of the laterally opposed pull wires in opposed axial directions and corresponding bi-directional deflection of the distal end portion of the sheath.
US09498601B2 Catheter tension sensing
This disclosure covers various concepts to use for obtaining measurement of tension in catheter pullwires to improve controllability of a robotic surgical system.
US09498598B2 Introducer sheath
A introducer sheath has a high centering performance that is relatively easily capable of introducing an elongated body such as a catheter into an appropriate position, and is capable of appropriately maintaining hemostasis and insertibility of a valve body. The introducer sheath includes a tubular member provided with a hollow section through which an elongated body is freely insertable, a hub that includes an inner space which communicates with the hollow section of the tubular member and is provided on a proximal side of the tubular member, a valve body that is placed in the inner space of the hub, and an annular member that contacts with the valve body to fix the valve body to the inner space and includes a through-hole into which the elongated body can be inserted.
US09498597B2 Device for instillation of a chemical agent into the endometrial cavity for purpose of global endometrial ablation
A device for chemical endometrial ablation comprising an outer tube, a moveable cervical collar surrounding a portion of the outer tube and located near the distal end of the outer tube, an inner tube movable in a distal-proximal direction within the lumen of the outer tube, a porous and/or sponge-like material on the distal end of the inner tube within the lumen of the distal end of the outer tube having a size, shape, and expandability so that when the distal end of the inner tube within the distal end of the outer tube is moved in a distal direction in relation to the outer tube, the porous and/or sponge-like material expands to the approximate size of a uterus so as to contact the endometrium, a source of cauterizing agent, and means to cause the cauterizing agent to flow through the lumen of the inner tube onto the porous and/or sponge-like material. In operation, the cervical collar can be moved or advanced along the outer tube to the cervix and secured tightly around the external portio in order to prevent chemical cauterizing agent from entering the vagina.
US09498590B2 Leak detection system and method for tube or catheter placement
The present disclosure relates to a leak detection system and method for tube or catheter placement. The system and method includes acoustically sensing a leak in the seal between a tube or catheter within a body and the body cavity against which it is sealed, assisting the user in adjusting the system until the leak has been substantially sealed, and establishing system parameters to be used thereafter to maintain the system in an operating state that will substantially prevent leakage, all using a noninvasive acoustic technique.
US09498587B2 Patch-sized fluid delivery systems and methods
A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.
US09498585B2 Apparatus and method for targeting a body tissue
An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member, when deployed into an expanded condition, has a framing member body which includes a three-dimensionally bulbous portion defining a maximum body footprint in a lateral dimension and has longitudinally spaced proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The proximal body end is attached to the target catheter. A protrusion has a diameter which is smaller than the maximum body footprint diameter. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway is substantially spaced apart from the framing member body.
US09498580B2 Hypodermic syringe apparatus having a needle guard assembly with shielding for protection from the needle after use
The present invention provides a novel construction for a hypodermic syringe apparatus by the inclusion of a needle guard assembly with shielding for protection of the needle after use and preventing of the spreading of disease and/or infection to users or localized personnel prior to disposal of the disposable syringe. The assembly includes a needle cover which is preferably tubular and is movable between a retracted positioned within the syringe and a deployed position extending around the needle for preventing contact therewith. A unique locking mechanism is included with two pins and two unlocking buttons for selectively initiating unlocking of the needle cover to facilitate movement of it to the deployed position responsive to activation of a needle cover button.
US09498579B2 Safety needle assembly
A safety needle assembly is provided herein having a hub; a needle fixed to the hub; a shield; a tab; a spring disposed between the shield and the hub configured to bias the shield distally; and, a clip disposed between the hub and the shield, the clip having a notch formed thereon shaped to permit passage therethrough of the tab. The clip and the tab releasably retain the shield in a first locked state against the biasing force of the spring thereby limiting distal movement of the shield relative to the hub; yet, in the first locked state, the shield is movable proximally relative to the hub. In the first locked state, the notch is spaced from the tab. The clip and the tab are relatively displaceable so as to align the notch with the tab and release the shield from the first locked state thereby allowing the shield to move distally, relative to the hub, to a second shielded state. In the second shielded state, the distal end of the needle is covered by the shield. Advantageously, with the subject invention, a passive safety needle assembly may be provided which requires few parts and is reliable.
US09498577B2 Dosing system
The invention concerns a dosing system for adjusting a dose volume of a fluid medium. The dosing system has a longitudinal center axis, a dosing sleeve with at least one communication opening, a dosing plunger, which can move axially in the dosing sleeve between a retracted and a depressed position to take up and dispense the medium through the communication opening, and a retraction limiting element to delimit a maximum axial retraction path of the dosing plunger. The retraction limiting element in at least one position can be axially fixed to the dosing plunger and can move radially to the longitudinal center axis between an inner position, axially fixed on the dosing plunger, and an outer position relative to the dosing plunger. In the inner position, it is completely inside the dosing sleeve. Furthermore, the dosing system has an end stop arranged on the dosing sleeve for interaction with the retraction limiting element in the retracted position of the dosing plunger.
US09498575B2 Substance delivery devices, systems and methods
A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, a plunger assembly slidably received within the tubular body at the proximal end thereof, and a hollow needle secured within the tubular body at the distal end thereof. The tubular body includes a longitudinal opening located between the proximal and distal ends that is adapted to allow a substance cartridge to be inserted within the tubular body. The plunger assembly includes a plunger that is in slideable sealing engagement with an inside wall of the tubular body, an engagement head positioned proximate an opposite end of the longitudinal opening, and a rod extending between and connecting the plunger and engagement head.
US09498573B2 Infusion pumps
Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.
US09498572B2 Double arm post support assembly
A support arm assembly includes a support arm, the support arm including a support arm connector hub and a support arm body; and a split arm, the split arm including a split arm connector hub and a support hub, the split arm connector hub connecting to the support arm connector hub.
US09498570B2 Bladder syringe fluid delivery system
A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.
US09498569B2 Syringe device, system and method for delivering ozone gas
In accordance with at least one exemplary embodiment, a syringe device, a method and a system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from a barrel of the syringe portion through the case. Conducting elements can be attached to the case and can breach the case. The conducting elements can be connected to electrodes. The electrodes can be attached to the syringe portion. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conducting elements from the ozone generator resulting in a corona discharge from at least one of the electrodes. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe portion delivered into a sterile field without compromise.
US09498568B2 System for packaging containers in a controlled environment
The invention relates to a packaging system (1, 20) of two or more objects or containers (2) in a controlled environment, able to contain a first container (1), equipped with a barrier of sterility, and a casing or package (20), externally coupled to the first container (1) and provided with at least one removable wall (8), so that said container (1) can be accessible from outside and/or can be decoupled from said casing or package (20).
US09498567B2 Systems and methods for controlling the return phase of a blood separation procedure
A method is provided for controlling the return phase of a blood separation procedure having a draw phase in which blood is drawn through an access or donor line, is separated, and a fluid, such as a cellular concentrate, is flowed into a reservoir, and a return phase in which fluid is flowed from the reservoir through the donor line. The method comprises flowing fluid from the reservoir through the donor line in a steady state return; monitoring the donor line for the presence of air; and, upon detecting air in the donor line, determining the amount of fluid remaining in the reservoir. Then, either i) the donor line is purged, if the amount of fluid remaining in the reservoir exceeds a predetermined amount, and the steady state return of fluid from the reservoir through the donor line is resumed; or ii) if the amount of fluid remaining in the reservoir does not exceed the predetermined amount, the return phase is ended by terminating the flow of fluid from the reservoir through the donor line.
US09498565B2 Breast fluid expression device
Disclosed herein are biologically inspired, either manual or electronic, portable fluid expression system to be used for, but not limited to, breast milk expression from nursing women and other milk expression from any species of mammal. The fluid expression systems can be configured to mimic the anatomy of a suckling infant and the biomechanics and fluid dynamics associated with this behavior. The fluid expression system can be used by nursing mothers to express breast milk efficiently, painlessly, and discreetly. The systems can include a single, contiguous flexible structure designed to resemble the lips and oropharyngeal cavity of a newborn infant of the mammalian species of interest. Rigid external housings or stiffening structures can be used to mimic the bony anatomy of the infant or mammalian species of interest.
US09498564B2 Shed-forming device for a weaving machine
A shed-forming device has elastically deformable selection elements (1) (28a)-(28f) which can be placed in an undeformed position or in a deformed position, electromagnetic selectors (2) which can be actuated in order to place or keep each selection element (1) in successive weaving cycles in one of said positions, and presenting means (3) in order to mechanically deform selection elements (1) in the direction of a selector (2) in each weaving cycle into a presenting position in which they are kept at a distance from the selector (2) by a stop (4), and also relates to a method for positioning selection elements of a shed-forming device in this manner.
US09498560B2 Interspinous spacer implant
An improved spinous process fixation implant assembly 50 includes a spinous process fixation implant 100 and an interspinous spacer implant 200. The spinous process fixation implant 100 includes elongated first and second components 110, 120, that are arranged opposite and parallel to each other. First and second spinous processes 90a, 90b of first and second adjacent vertebrae 80a, 80b are clamped between the first and second components 110, 120, respectively, and are separated by the interspinous spacer implant 200. The interspinous spacer implant 200 may be inserted between the spinous processes of adjacent vertebrae from two different directions.
US09498554B2 Dispensing device
A dispensing device for release of an air treatment material includes a semi-permeable substrate having a mesh size between about 15 strands per cm to about 79 strands per cm and a support component for supporting the semi-permeable substrate. The dispensing device releases the air treatment material at a rate of at least about 0.05 mg/hr at about 25° C.
US09498553B2 Aroma-diffusing heating device using a replaceable aroma capsule and the aroma capsule
An aroma-diffusing heating device includes a heating base, and an aroma capsule detachably accommodated in the heating base and heatable by the heating base to give off fragrance. The aroma capsule includes a heat-transfer container defining a top opening, an aromatic substance held in the heat-transfer container, and a breathing film bonded to the heat-transfer container in the top opening of the heat-transfer container. The breathing film has open spaces defined therein.
US09498552B2 Compositions and methods for eliminating microbial growth and preventing odors in vehicle HVAC systems and passenger cabin and truck environments
A mist-generating device that can be connected to a vehicle's Low Direct Current Voltage (LDCV) power supply is disclosed. The device can be used to treat mold, bacteria and clean or remove odors on exposed and hard-to-reach surfaces of the interior of a car. The device can include a unique filling system that can be used to prevent foreign materials from entering into the unit, including fluids or substances that would deteriorate the performance of the unit or the components of the device itself. The inside of the device can include an internal anti-foam and anti-splash structure designed to keep electronic components dry and reduce the foaming and turbulence of the fluid being misted. Further, the inside of the device in one embodiment is split into three adjacent areas, which govern efficient flow of air and atomized chemicals through the device.
US09498545B1 Environmentally responsive hydrogels for delivery
A nanosensor-containing polymer composition for the monitoring of physiological parameters and a method for making the composition are disclosed. The composition includes a fluid nanosensor-containing polymer that becomes rigid in the presence of physiological conditions. In the fluid form, the composition can be suitable for injection on to or into the skin. In the rigid form, the nanosensor is substantially immobilized in the polymer. The method includes forming a mixture comprising a nanosensor and polymer precursor(s), subjecting the mixture to conditions suitable for forming the fluid form of the composition; and subjecting the fluid form to physiological conditions to provide a rigid nanosensor-containing composition.
US09498544B2 Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents
The invention provides methods of preventing or treating diseases or disorders caused by biological agents or chemical agents in a subject (e.g., a mammal, such as a human) by administering genetically modified human umbilical cord perivascular cells.
US09498543B2 Antibody drug conjugates
The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
US09498542B2 Tetrameric cytokines with improved biological activity
The present invention concerns methods and compositions for forming cytokine-antibody complexes using dock-and-lock technology. In preferred embodiments, the cytokine-MAb DNL complex comprises an IgG antibody attached to two AD (anchor domain) moieties and four cytokines, each attached to a DDD (docking and dimerization domain) moiety. The DDD moieties form dimers that bind to the AD moieties, resulting in a 2:1 ratio of DDD to AD. The cytokine-MAb complex exhibits improved pharmacokinetics, with a significantly longer serum half-life than either naked cytokine or PEGylated cytokine. The cytokine-MAb complex also exhibits significantly improved in vitro and in vivo efficacy compared to cytokine alone, antibody alone, unconjugated cytokine plus antibody or cytokine-MAb DNL complexes incorporating an irrelevant antibody. In more preferred embodiment the cytokine is G-CSF, erythropoietin or INF-α2b.
US09498540B2 Cell proliferation inhibitors and conjugates thereof
Disclosed herein are immunoconjugates comprising an inhibitor of Eg5 linked to an antigen binding moiety such as an antibody, that are useful for treating cell proliferative disorders. Also disclosed are novel inhibitors of Eg5 that can be used either alone or as part of an immunoconjugate to treat cell proliferation disorders. The Eg5 inhibitors include compounds of this formula as described herein: The invention further provides pharmaceutical compositions comprising these compounds and immunoconjugates, and compositions comprising the immunoconjugates or compounds with a therapeutic co-agent, and methods to use these compounds, conjugates and compositions for treating cell proliferation disorders.
US09498539B2 Affinity-based controlled release system
Prolonged or extended release of bioactive protein is achieved using an affinity-based approach which exploits the specific binding of Src homology 3 (SH3) domain with short proline-rich peptides. Specifically, methylcellulose was modified with SH3-binding peptides (MC-peptide) with either a weak affinity or strong affinity for SH3. Controlled release of chondroitinase ABC (ChABC) is also described.
US09498535B2 Wound healing using topical systems and methods
The present invention generally relates to compositions and methods for topical or transdermal delivery and treatment of wounds and/or promoting wound healing. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin, e.g., wounded skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.
US09498532B2 Antibody drug conjugates
The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
US09498530B2 Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
US09498528B2 Treatment of multiple sclerosis (MS)
A method for treatment of multiple sclerosis (MS) with Campath-1H with significant efficacy and a favorable safety profile is described, which offers an acceptable benefit/risk ratio. Especially described is the use of Campath-1H (alemtuzumab) for the production of a medicament for the treatment of multiple sclerosis (MS), comprising a first treatment cycle followed by at least one further treatment cycle of Campath-1H (alemtuzumab), in which each treatment cycle comprises 1-5 daily doses which are applied on consecutive days, wherein the daily dose is >0 and ≦12 mg, and wherein each treatment cycle is separated from the next cycle by at least 1-24 months. Also described are treatment regimens comprising the administration of less than 12 mg/day of Campath-1H for a period of 1-5 consecutive days.
US09498524B2 Method of vaccine delivery via microneedle arrays
A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.
US09498523B2 Bifidobacterium for dust mite allergy
A composition comprising Bifidobacterium breve for use in improving lung function in human subjects suffering from dust mite allergy.
US09498520B2 Use of proteases for gluten intolerance
The present technology relates to an enzyme composition. The enzyme composition may be used to treat gluten intolerant subjects, including suffering from non-Celiac gluten intolerance and/or non-Celiac gluten sensitivity. The enzyme composition may also be used to reduce gluten exposure in certain individuals. For example, the enzyme composition may also be used as a prophylactic to reduce exposure to gluten oligopeptides.
US09498517B2 Stanniocalcin-1 (STC-1) therapy for treatment of retinal diseases
The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
US09498515B2 Compositions and methods for treatment during non-acute periods following CNS neurological injury
This invention relates to treatment of neuroinjury in a post-acute window or in a chronic period following neuroinjury.
US09498514B2 Systems, compositions, and methods for transplantation and treating conditions
Systems and methods for purification and concentration of autologous alpha-2 macroglobulin (A2M) from whole blood and or recombinant A2M are provided. Also provided are methods of treating wounds with A2M. Methods for utilizing A2M in combination with other treatments (e.g., platelets and other growth factors) are provided in addition to combinations with exogenous drugs or carriers. Also provided is a method of producing recombinant A2M wild type or variants thereof where the bait region was modified to enhance the inhibition characteristics of A2M and/or to prolong the half-life of the protein for treating wounds.
US09498512B2 Powerful MHC-class II peptides derived from survivin
The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
US09498508B2 Pharmaceutical composition for treating cancers and preparation method therefor
A pharmaceutical composition for treating cancers and preparation method thereof. Said composition for treating cancers contains Chinese medicinal materials including Rhizoma Pinelliae, Rhizoma Arisaematis, Rhizoma Gastrodiae etc., and said preparation method is in accordance with a conventional Chinese medicinal preparation method, manufacturing said composition to form any one of the ordinary oral preparations.
US09498507B2 Antiviral composition
The present invention relates to a composition comprising extract of the plant Ficus arnottiana. The invention also relates to a process for the preparation of the composition and to the composition for the use in the treatment of viral infections, particularly caused by herpes simplex viruses (HSV). The invention further relates to a method of treating a viral infection in a mammal comprising administering to the mammal a therapeutically effective amount of the composition.
US09498506B2 Pharmaceutical composition for preventing or treating thyroid diseases, comprising extract from Lonicera caerulea L. var. edulis fruits as active ingredient
The present invention relates to a pharmaceutical composition for preventing or treating thyroid diseases and a food composition for improving thyroid function, comprising an extract from Lonicera caerulea L. car. Edulis fruits as an active ingredient.The composition of the present invention may be useful for preventing or treating thyroid diseases such as hypothyroidism, hyperthyroidism, thyroid nodule, or thyroditis, and improving thyroid function. Since the extract from Lonicera caerulea L. car. Edulis fruits, which is an active ingredient of the present invention, is derived from natural products, there is no concern for side effects such as toxicity compared to synthetic medicine.
US09498502B2 Prevention and treatment of allergic diarrhea
Bifidobacterium breve CNCM I-3865 (NCC2950), a composition comprising Bifidobacterium breve CNCM I-3865 (NCC2950), and the use of Bifidobacterium breve CNCM I-3865 (NCC2950) in the prevention or treatment of allergic diarrhoea are provided. The Bifidobacterium breve CNCM I-3865 (NCC2950) can be in a non-replicating form and can be administered to at least partially treat allergic diarrhoea or at least partially reduce the risk of developing allergic diarrhoea.
US09498499B2 Imaging-aided gene therapy using mesenchymal stem cells as target-delivery vehicle
Compositions and methods of use thereof encompass engineered mesenchymal stem cells as a vehicle to deliver secreted tissue necrosis factor-RGD4C fusion polypeptides for tumor treatment, thereby reducing side effects of TNF. A reporter gene can be included in vector constructs to monitor the localization and viability of engineered MSCs after administration into a recipient animal. The genetically modified mesenchymal stem cell can comprise an expression cassette comprising a nucleic acid sequence operably linked to a gene expression promoter and encoding the heterologous fusion polypeptide comprising a tissue necrotic factor region and an integrin-binding region. Another aspect of the disclosure encompasses embodiments of a method of modulating the proliferation of a targeted population of tumor cells by delivering a population of the genetically modified mesenchymal stem cells to tumor cells, allowing the mesenchymal stem cells to express the heterologous polypeptide, thereby reducing the proliferative capacity of the tumor cells.
US09498493B2 Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo
The invention provides compositions comprising a carrier comprising a continuous phase of a hydrophobic substance, liposomes, and a polynucleotide, and methods for using such compositions for delivering a polynucleotide to a subject.
US09498488B2 Method of treating acute coronary syndromes
The present invention relates to methods and compositions designed for the treatment or management of acute coronary syndromes, particularly, unstable angina and acute myocardial infarction. The methods of the invention comprise the administration of an effective amount of a formulation containing one or more therapeutic agents which specifically decreases or inhibits the activity of phagocytic cells and/or eliminates or diminishes the amount of phagocytic cells including, but not limited to, macrophages and monocytes. The formulations are specifically targeted to phagocytic cells. The invention also provides pharmaceutical compositions of formulations containing one or more therapeutic agents of the invention for administration to subjects currently suffering from or having recently suffered an acute coronary syndrome such as unstable angina and acute myocardial infarction.
US09498480B2 Substituted azabicycles and use thereof
The present application relates to novel substituted azabicycles, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
US09498479B2 Dihydropyrimidine compounds and their application in pharmaceuticals
Provided herein are dihydropyrimidine compounds and their pharmaceutical applications, especially for use in treating and preventing HBV diseases. Specifically, provided herein are compounds having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof, wherein the variables of the formulas are as defined in the specification. Also provided herein is the use of the compounds having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof for treating and preventing HBV diseases.
US09498473B2 Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance
Compositions of hepatic therapeutic actives from one or more acridone compounds, one or more xanthone compounds, one or more thioxanthone compounds, one or more tocotrienol compounds, and one or more oleanolic triterpenoid compounds. Also, methods for treating various liver diseases or certain cancers with such hepatic therapeutic actives, as well as providing liver health maintenance.
US09498470B2 Antiviral drugs for treatment of arenavirus infection
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever.
US09498469B2 Compositions and methods for enhancing brain function
Compositions and methods are provided that enhance cognition in a human to which the composition is orally administered. Remarkably, clinical studies have proven that contemplated compositions achieved the desired effects using a minimal number of active ingredients at or near threshold active dosages, wherein such compositions almost exclusively comprise huperzine A, vinpocetine or rhodiola, and acetyl-L-carnitine, and optionally further include alpha lipoic acid, rhodiola, and biotin.
US09498468B2 Rhinitis treatment regimens
A method of treating rhinitis and rhinorrhea includes taking a daytime oral dosage unit containing a non-sedating antihistamine for treating rhinitis and an anticholinergic agent having limited capacity to cross blood-brain barrier for treating rhinorrhea, and taking a nighttime oral dosage unit containing a non-sedating anticholinergic agent that has limited capacity to cross blood-brain barrier and that is in a lower amount than the amount in the daytime oral dosage unit for treating rhinorrhea or no anticholinergic agent. A treatment regimen for rhinitis with rhinorrhea includes a daytime oral dosage unit containing a non-sedating antihistamine for treating rhinitis and an anticholinergic agent having limited capacity to cross blood-brain barrier for treating rhinorrhea, and a nighttime dosage unit containing a non-sedating anticholinergic agent that has limited capacity to cross blood-brain barrier and that is in a lower amount than the amount in the daytime oral dosage unit for treating rhinorrhea or no anticholinergic agent.
US09498461B2 Compositions and methods for the treatment of inflammatory bowel disease
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of gastrointestinal diseases and inflammation such as inflammatory bowel disease, ulcerative colitis, mild-to-moderate Crohn's disease, rheumatoid arthritis, inflammatory arthritis, psoriatic arthritis, liver cirrhosis and idiopathic urticaria.
US09498458B2 Method of inhibiting or treating fibrosis
A compound of Formula (I) or a metabolite thereof, or an ester of the compound of Formula (I) or the metabolite thereof, or a pharmaceutically acceptable salt of each thereof, wherein Formula (I), m, n, X1 and X2 are as defined herein, is useful for inhibiting, reducing, or treating fibrosis, conditions leading to or arising from it, and/or negative effects of each thereof.
US09498457B2 Hypotensive prostamide-containing biodegradable intraocular implants and related implants
Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or reduce a at least one symptom of an ocular condition, such as glaucoma.
US09498456B2 Pharmaceutical formulation containing gelling agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
US09498450B2 1-aminocyclohexane derivatives for the treatment of cochlear tinnitus
The present invention relates to the treatment of an individual afflicted with cochlear tinnitus comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.
US09498446B2 Pharmaceutical compositions resistant to abuse
The present invention provides immediate release pharmaceutical compositions for oral administration that are resistant to abuse.
US09498443B2 Stable formulations for lyophilizing therapeutic particles
The present disclosure generally relates to lyophilized pharmaceutical compositions comprising a sugar, a cyclodextrin, and polymeric nanoparticles comprising a copolymer and a therapeutic agent which, upon reconstitution, have low levels of greater than 10 micron size particles. Other aspects of the invention include methods of making such nanoparticles.
US09498442B2 Rifaximin powder, process for preparing the same an controlled release compositions containing said rifaximin useful for obtaining a long-lasting effect
The present invention describes rifaximin powder and to a process for preparing the same. The invention relates also to a pharmaceutical composition in solid form comprising said rifaximin, pharmaceutically acceptable excipients and optionally other ingredients. The compositions according to the invention are suitable for oral administration and are characterized by producing a controlled release of rifaximin, whereby a long-lasting effect is obtained in a patient.
US09498441B2 Nitazoxadine composition and process to prepare same
Disclosed is a pharmaceutical nitazoxanide composition comprising: (a) an immediate release fraction comprising nitazoxanide non-coated granules or non-granulated powder, and (b) a pH-dependent release fraction comprising granules of nitazoxanide coated with one or more polymers having a pH-dependent solubility.
US09498439B2 Prodrug compositions, prodrug nanoparticles, and methods of use thereof
Nanoparticles comprising a prodrug and prodrugs linked to phospholipids, wherein the linkages facilitate release of the prodrugs from the nanoparticles to sites within a target cell or cell membrane by fusion of the particle and the cell membrane are disclosed. Also disclosed are methods for producing and using the nanoparticles and their constituents.
US09498421B2 Two component compositions containing tetrabasic zinc-amino acid halide complexes and cysteine
Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
US09498418B2 Abradable films for use in oral care
The present invention relates to abradable films useful, e.g., in dentifrice formulations, wherein the film is stable in formulation, but abrades to release pigment or oral care active components upon brushing. The invention provides, e.g., an orally acceptable, water insoluble film which does not dissolve under formulation conditions but disintegrates upon brushing, comprising a polymer matrix, plasticizer (e.g., propylene glycol), releasable material (e.g., color or pigment) incorporated therein; and (optionally) nonionic surfactant (e.g. polysorbate), wherein the polymer matrix comprises at least 50%, e.g., at least 75%, of poly(vinyl alcohol), and 50% or less, e.g. 25% or less, of a water-soluble cellulose ether, for example hydroxypropyl methyl cellulose; together with dentifrice comprising such films, and methods of making and using the same.
US09498417B2 Bleaching and colouring composition for hair
Present invention relates to an aqueous composition for bleaching and coloring hair which comprises direct dyes and an oxidizable solvent in addition to a compound with a bleaching effect, an alkalizing agent and an oxidizing agent. It is furthermore the object of the present invention is the use of oxidizable solvent, preferably an aromatic or aliphatic alcohol for stabilizing a direct dye in an aqueous composition comprising at least one compound with hair bleaching effect, at least one oxidizing agent and at least one alkalizing agent.
US09498414B1 System and method for reducing plaque on teeth
A system and method which enables application of a composition of matter to teeth (and gums), which composition of matter remains in contact with, and adheres to, said teeth and gums for a period long enough to neutralize acids in dental plaque biofilm, inhibit plaque from adhering to teeth and gums, encourage removal of dental plaque, and form a barrier between the teeth and gums and the oral environment.
US09498405B2 System and method for providing tempered fluid
The present invention is directed to methods and apparatus for tempering the temperature of a liquid in a fluid conducting system. More particularly, some embodiments of the invention relates to tempering the temperature of water supplied to a fixture from a water heater in a fluid conducting system. The system can include a heater for heating the fluid and a diffuser for slowing the rate at which water provided to a decontamination fixture is heated.
US09498404B2 Fluidic methods and devices
A device for use by an individual for sexual pleasure varying in form, i.e. shape, during its use and allowing for the user to select multiple variations of form either discretely or in combination and for these dynamic variations to be controllable simultaneously and interchangeably while being transparent to the normal use of the device, including the ability to insert, withdraw, rotate, and actuate the variable features manually or remotely. According to embodiments of the invention localized and global variations of devices are implemented using fluidics and electromagnetic pumps/valves wherein a fluid is employed such that controlling the pressure of the fluid results in the movement of an element within the device or the expansion/contraction of an element within the device.
US09498403B2 Automatic salivation facilitating apparatus
Provided is an automatic salivation facilitating apparatus including a first parotid gland massaging device which massages user's one-side parotid gland, a second parotid gland massaging device which massages user's other-side parotid gland, a first fixing member which connects the first and second parotid gland massaging devices and allows the user to wear the automatic salivation facilitating apparatus, a salivation agent injection unit which is disposed to a lower portion of one of the first and second parotid gland massaging devices to periodically automatically inject salivation agent, and a controller which operates a main body. The automatic salivation facilitating apparatus utilizes a submandibular gland massaging device together with the salivation agent injection unit and the parotid gland massaging devices, so that the effect of facilitating salivation can be maximized.
US09498397B2 Dual column surgical support system
A surgical patient support includes a foundation frame, a support top, and a brake system. The foundation frame includes a first column and a second column. The support top is coupled to the first column and the second column for rotation about a top axis extending along the length of the support top.
US09498395B2 Joint movement detection device and system for coordinating motor output with manual wheelchair propulsion
A joint movement detection device and system is presented which is responsive to elbow or wrist movements during use of a manually-propelled wheelchair to enable coordination of assistive motor energization with a user's efforts at self-motivating the manually-propelled wheelchair during driving, steering, and braking of the wheelchair. Several embodiments are provided which help to ensure user-intended assistive motor output that is responsive to movement of the joint over which the device is worn.
US09498394B2 Absorbent pad, absorbent article, and method for manufacturing an absorbent pad
An absorbent article for use with a RF reader includes an absorbent pad and a RFID tag. The absorbent pad includes a lining layer, a liquid-impermeable layer, an absorbent layer, and a plurality of sensing wires. The liquid-impermeable layer is attached to the lining layer. The absorbent layer is disposed between the lining layer and the liquid-impermeable layer. The lining layer and the liquid-impermeable layer define a receiving space having an opening located at a side portion of the absorbent pad. The sensing wires are provided on the absorbent layer and extend into the receiving space. The RFID tag is received in the receiving space and contacts electrically the sensing wires when received in the receiving space.
US09498391B2 Method of constructing absorbent articles comprising graphics
An absorbent article may comprise a first zone comprising graphics and a second zone comprising graphics, wherein the first and second zones have different elastic properties. Further, the absorbent article may comprise a first absorbent article component and a second absorbent article component having substantially different elastic properties, wherein the first absorbent article component comprises an elastomer. Additionally, the absorbent article may comprise a third absorbent article component overlapping the first and second absorbent article components, wherein the third absorbent article component comprises graphics on at least the portions which overlap the first and second absorbent article components.
US09498387B2 Absorbent article having bent sections
An absorbent article has a lengthwise direction and a widthwise direction. The absorbent article includes a body section provided with a liquid-permeable top sheet on a skin-side, a liquid-impermeable backsheet on a garment-side, and a liquid-holding absorbent body positioned between the top sheet and the backsheet; and wing sections extending outwardly from both side-edges of the body section in the widthwise direction. A surface of the wing sections on the skin-side is formed by the top sheet or from side sheets positioned on both sides in the widthwise direction of the top sheet. Furthermore, the surface of the wing sections on the skin-side includes a plurality of bending parts extending non-continuously in the lengthwise direction, arranged in the widthwise direction, and having a substantially U-shaped cross-sectional shape in the widthwise direction.
US09498383B2 Swab applicator and methods of use
A swab applicator for collecting debris and other materials from small and hard to reach spaces and cavities and applying materials to selected areas, including small and hard to reach spaces and cavities. The swab applicator includes an elongated member having two opposite ends having respective end members extending from the ends. One of the end member loops to form one or more through openings and has a surface made from or covered with an absorbent material. The other end member is different from the first end member and, in one configuration, is a wad mounted on the end of the elongated member.