Document Document Title
US09410335B2 System and method for plugging core holes
A system, device, and method for plugging core holes. A core hole plug includes a top compression plate, a bottom compression plate, and a rubber expansion ring that separates the top and bottom compression plates. A beveled screw hole can be created on the top compression plate. The beveled screw hole matches the angle of the bottom surface of the head of a flat head bolt to ensure that the bolt remains flush with the top compression plate. The rubber expansion ring can be squeezed between the top and bottom compression plates as the flat head bolt is screwed into a threaded receiver nut formed on the bottom compression plate. An installation tool can be utilized to install the core hole plug so that the top compression plate remains flush with an existing floor surface.
US09410334B2 Mobile concrete pump with distributing boom and support device
A mobile concrete pump with a support structure, which can be placed on a vehicle frame of a truck chassis, for receiving functional units which form a support device and a distributing boom. The functional unit which forms the distributing boom has a rotary head mounted on a boom pedestal in a rotatable manner about a vertical axis, the boom pedestal being secured to the support structure, and the boom pedestal comprises a tank which engages into the support structure and is provided as a rotary bearing for the rotary head. Each functional unit which forms the support device has a support leg mounted in a bearing in a pivotal and/or telescopable manner, the bearing being secured to the support structure. A tank wall of the tank tapering from the top to the bottom in a truncated cone-like manner or in a truncated pyramid-like manner in the cross section, engages into the support structure and is rigidly secured, preferably welded, into the support structure.
US09410327B2 Joint guard for panels
A joint guard provided for protecting, and stabilizing portions in the edge region of a panel, the portions being selected from the group consisting of a distal edge, a downwards protruding heel, a upper joint edge, a groove, a lower cheek, a distal end, an upwards protruding lower cheek heel, an upper joining edge, an undercut, a moveable locking element, a locking tongue, a locking tongue leg and a maneuvering leg.
US09410324B2 Method of roof covering with roof covering elements (tile-like sheets)
A method for covering a roof with tile-like roof covering elements each having assembling holes at the corners, wherein the edges of the roof covering elements are overlapped such that the assembling holes align and are mounted together with screws. Additionally, one or more of the roof covering elements can be mounted to at least one roof batten with a cramp and screw.
US09410321B2 High performance, reinforced insulated precast concrete and tilt-up concrete structures and methods of making same
The invention comprises a product. The product comprises a foam insulating panel, the panel having a first primary surface and an opposite second primary surface, wherein the foam insulating panel defines at least one recessed channel in the first primary surface, the at least one recessed channel being sized and shaped to provide a mold for a structural reinforcing member. The product also comprises a concrete panel formed on the first primary surface and filling the at least one recessed channel so as to provide a structural reinforcing member for the concrete panel. The product further comprises an elongate anchor member in the foam insulating panel and extending from the first primary surface of the foam insulating panel into the concrete panel. A method of making a composite reinforced insulated concrete structure is also disclosed.
US09410320B2 Reinforced concrete structure
A main reinforcing bar has a strength transition portion between a normal strength portion and a high strength portion. The high strength portion is arranged in a joint section. The boundary between the normal strength portion and the strength transition portion is configured as a deigned point. The designed point is designed such that, at the time of an earthquake, the main reinforcing bar yields at the designed point before the main reinforcing bar yields at the root of the beam at of the joint section. The boundary between the high strength portion and the strength transition portion is located in the joint section, and the root of the beam is located at the strength transition portion. The strength of the strength transition portion at the root of the beam is equal to or higher than the required strength.
US09410319B2 Heat and pressure generated design
A wood fiber based panel with surfaces layer with lower parts which has less binders than the upper parts. Also, a method of manufacturing a building panel having a structured surface with a design that has color variation in register with the structure obtained by a varying pressure distribution applied on the surface.
US09410316B2 Post-tension concrete leave out splicing system and method
Devices, systems, and methods for constructing post-tensioned concrete slabs in a new floor construction that has a reduced gap distance between the slabs. The devices, systems, and methods can improve project construction time by reducing the time delay in accessing the floor underneath the slabs due to safety and/or weather conditions.
US09410315B2 Curtain wall panel bracket leveling system
Various embodiments of the present disclosure provide a curtain wall panel bracket leveling system that facilitates leveling a panel bracket mounted to a fixture (such as an embedment or an anchor array) cast in a concrete slab.
US09410314B1 Modular floodwall construction elements
A system of modular, hollow interlocking elements which are made of tough flexible lightweight material, which can be connected in order to form a stable continuous, multi-directional structure, requiring no adhesives or other stabilizing materials and can be filled with any required filling materials such as sand or locally available filling materials for use as low shaped dams, a flood protection barrier or in any need to change the course of water or fluid. The various modular elements that make up the structure can be provided by shapes having four, five, six, seven or eight walls, all identical in function, enabling quick construction of a water flood barrier, or an acoustic insulation wall, with easy adjustment of its height, length or width.
US09410312B2 Deployable portable shelter
A shelter has a packaged configuration and a deployed configuration. The shelter has four panels, each with four edges and two faces. The first and fourth panels have a rectangular shape, and the second and third panels have a quadrangle shape. The relationship of panel edge lengths and angles of the quadrangle shelter panels create a sturdy enclosure that is easy to erect, manipulate, and reconfigure. Furthermore, the shelter may be erected by rotating the panels into place via pivotal connections between the panels and optionally through the use of a lever arm.
US09410311B2 Dual flush device
The devices and methods described, provide for a dual flush device with a handle sleeve with a rotation stop and a lift arm extending through the handle sleeve with a rotation limiting tab on the lift arm to engage the rotation stop to enable the lift arm to rotate in a first direction through a first arc and to rotate in a second direction through a second arc where the first arc is smaller than the second arc. A dual flush device with a lift arm added to conventional toilet will enable the toilet to perform two different flush actions, a small partial flush for liquid waste, and a second, full flush for solid waste.
US09410309B2 Wall shower bar assembly
A wall shower bar assembly (100) mounted to a shower wall (10). The wall shower bar assembly (100) includes: a tube assembly (200), an upper retainer assembly (300) for coupling an upper portion (102) of the bar assembly to a water supply pipe (12), and a lower retainer assembly (400) for coupling a lower portion (104) of the bar assembly to the wall. The upper and lower retainer assemblies (300, 400) define a dual joint connection structure (110) including an upper spheroidal joint connection assembly (112) and a lower pivot joint connection assembly (114). Both the upper and lower joint connection assemblies (112, 114) permit relative pivoting movement of the bar assembly (200) about pivot axes (P1, P2) substantially parallel to the wall. The lower retainer assembly 400 includes a suction cup retaining assembly (410) including a camming mechanism (420) for securing a section cup (412) to the wall.
US09410301B2 Patch system and method for oil boom
An apparatus, system, and method for repairing or reinforcing a damaged oil containment boom. The apparatus includes two end connectors and a curtain attached between the two end connectors. The end connectors are attached to a damaged, existing boom via a vertically extending slot formed in each of the end connectors. After attachment, a tight seal is formed between the curtain and the damaged boom. The method for reinforcing a boom includes engaging the two end connectors to an existing boom while stretching the curtain over the damaged boom section in an overlapping relationship. Finally, the connectors are locked into place via a lock-pin mechanism. This invention creates a tight seal over the damaged area, creating a “patch” to keep out oil contaminants from the protected area. The disclosed invention can be used to repair, patch, or reinforce an existing oil containment boom.
US09410296B2 Apparatus and related methods of paving a subsurface
Disclosed may be an intermediate surface for supporting a small paver, wherein the surface can also be used to exchange heat with the pavers. In one embodiment, the apparatus may be a hextray defined by a frame with a hexagonal lattice for supporting pavers. The hextray preferably features a tubing track throughout the lattice to accommodate heat exchange tubing. In operation the hextray may be positioned above a pedestal or directly on a subsurface. In embodiment, the hex tray may be outfitted with insulation and a metal plate so that heat may be exchanged with pedestals via fluid passing through tubing installed throughout the hexagonal lattice. In a preferred embodiment, the hextray features a slot in its corners for receiving a locking disk or locking slider.
US09410295B2 Rail system, in particular for an in-floor electric conveyer system
A rail system for an in-floor electric conveyer system having a main track with at least two fixed parallel rails, at least two secondary tracks which enclose an angle and each have fixed rails, and a switch arranged between the main track and the secondary tracks. Each rail of the main track is assigned a moveable rail section connected to the corresponding rail of the main track via a joint. Each joint has at least one end face of the rail of the main track embodied as part of a rotational face about the axis of a pivot pin, at least one end face, embodied in a complementary fashion thereto, of the assigned movable rail section and at least one transition body, which overlaps the fixed rail and the movable rail section and is connected in one end region to the fixed rail, and in the other end region to the movable rail section in an articulated fashion.
US09410294B2 Railway rail support plate
This invention relates to a support plate for supporting a railway rail on a rail support member, said support plate comprising a lower surface for directly or indirectly contacting a mounting surface of the rail support member, an upper surface for directly or indirectly supporting the rail, and an intermediate region interposing the upper and lower surfaces, for reducing support plate weight.
US09410293B2 High-speed railway aerodynamic sleeper
A high-speed railway aerodynamic sleeper (1) including one central area (2), two support areas (3) on each side of the central area (2), on which the rails are placed, and two outer areas (4), located at the ends of the sleeper (1), following the support areas (3). The cross-section of the sleeper (1) includes, on the central area (2), and the support areas (3), and the two outer areas (4), a first bottom section (5) comprising a first polygon (7) having at least 4 sides and a second top section (6) having at least one second polygon (8) of n sides, n being≧4, the first bottom section (5) and the second top section (6) being attached to each other, and the top base (10) of the first polygon (7) and the bottom base (9) of the second polygon (8) share their sides.
US09410292B2 Multilayered tissue having reduced hydrogen bonding
The disclosure provides a multilayered tissue web comprising treated cellulosic fibers selectively disposed in one or more layers, wherein the tissue layer comprising treated fibers is adjacent to a layer comprising untreated fiber and which is substantially free from untreated fiber. Generally the treated fibers have a rate of substitution of about 0.02 to 0.07. In this manner, the disclosure provides a multi-layered tissue web having treated fiber selectively incorporated therein, where the tissue web has basis weight greater than about 10 grams per square meter (gsm), such as from about 10 to about 50 gsm, a sheet bulk greater than about 8 cc/g, such as from about 8 to about 15 cc/g and Stiffness Index less than about 15, such as from about 8 to about 12.
US09410285B2 Method for catalytic oxidation of cellulose and method for making a cellulose product
In a method for catalytic oxidation of cellulose a heterocyclic nitroxyl radical is used as catalyst, hypochlorite is used as main oxidant acting as oxygen source, and a tertiary amine or chlorine dioxide as an activator of the heterocyclic nitroxyl radical.
US09410284B2 Cushioning-material surface layer and hot-press cushioning material
The cushioning-material surface layer 11a includes a resin layer 12 disposed on one side of the surface layer 11a to cover the side thereof, a rubber layer 13 disposed on the other side of the surface layer 11a to cover the side thereof, and a woven fabric layer 14 disposed between the resin layer 12 and rubber layer 13 and including bulked yarns for at least one of warp and weft. The woven fabric layer 14 includes a woven fabric-resin composite layer 17 disposed on the resin layer 12 side and formed by impregnating part of the woven fabric with resin that forms the resin layer 12, and a woven fabric-rubber composite layer 18 disposed on the rubber layer 13 side and formed by impregnating part of the woven fabric with rubber that forms the rubber layer 13. The woven fabric layer 14 includes interstices 20 therein.
US09410278B2 Washing machine and washing method
A washing machine and a washing method, comprises an inner cylinder, an outer cylinder, and solid particles as washing medium. The inner cylinder is driven into rotation by a driver device. The inner cylinder has arranged on the inner wall thereof scraper blades that protrude inwards and are bent along the wall of the inner cylinder. The scraper blades drives the particles into obliquely upward or obliquely downward movements and flipping, thus allowing for more fully mixing clothes with the particles, for simplified washing process, while also for improved cleaning rate, and for facilitated recycling of the particles.
US09410275B2 Thread holding mechanism of sewing machine, needle threader thereof, and sewing machine
A thread holding mechanism of a sewing machine which holds a thread supplied from a thread supply source includes a thread gripper unit that grips one end of a supplied thread, and a thread presser unit structured in a unified manner with the thread gripper unit and provided between the thread gripper unit and the thread supply source. Provided at the thread-supply-source side is a thread guide that guides another end of the thread, and when the thread gripper unit descends below the thread guide, the thread presser unit abuts the thread.
US09410271B2 Decorative engineered self hem
A decorative engineered self-hem and a method to prepare the decorative engineered self-hem in a single fabric is disclosed herein. It is prepared without having any additional cut and sew, with various weave patterns designed in a design area 10-20 inches from a selvedge area and the rest of the fabric is woven in conventional weave pattern such as satin/twill. The method of preparation includes cutting the fabric parallel to a selvedge area; folding the fabric overlapping the selvedge area; and folding the full fabric horizontally and, at the same time, hemming of edge of the selvedge area to finish.
US09410269B2 Method and device for crimping a multifilament thread
A method and a device for crimping a multifilament thread are described. The thread is blown by means of a transport nozzle through a compressed air stream guided in a thread channel into a gas-permeable compression chamber. Inside the compression chamber, the thread is compressed to form a thread plug, which is then continuously removed through an outlet of the compression chamber. The compression and the removal of the thread plug are monitored by measuring the pressure of the compressed air stream. According to the invention, a plurality of pressures of the compressed air stream in the compression chamber are measured at a plurality of measurement points distributed over the length of the compression chamber for monitoring the thread plug formation in order to perform the compressing and cooling of the thread plug with a uniform filling of the compression chamber.
US09410268B2 Method for preparing carbon nanotube fibers with improved spinning properties using surfactant
The present invention provides a method for preparing carbon nanotube fibers with improved spinning properties using a surfactant and carbon nanotube fibers prepared by the method. According to the method for preparing carbon nanotube fibers of the present invention, the addition of a surfactant during the preparation of carbon nanotubes interrupts and delays the agglomeration of catalyst particles, which reduces the size of the catalyst particles and uniformly disperses the catalyst particles that play a key role in the formation of carbon nanotube fibers, thus increasing the strength and conductivity of carbon nanotube fibers and improving the spinning properties. While convention methods prepare carbon nanotube fibers by injecting a catalytic material for the synthesis of carbon nanotubes in a high-pressure supercritical state to be uniformly dispersed, the present invention uses a dispersant and thus does not require the injection in a high-pressure supercritical state.
US09410264B2 Ingot growing apparatus
An ingot growing apparatus. A main chamber includes a crucible accommodating a source material therein and a heater melting the source material by heating the crucible. A dome chamber is disposed on top of the crucible. A pull chamber is disposed on top of the dome chamber. An ingot grown in the crucible moves via a seed cable within the dome chamber and the pull chamber. A weight-measuring unit is disposed on top of the pull chamber. The weight-measuring unit includes a housing disposed on top of the pull chamber, with the interior thereof being maintained in a vacuum state, a support roller disposed within the housing to support the seed cable, and a load cell disposed outside of the housing to measure a weight of the ingot supported by the support roller.
US09410262B2 Method for producing a silicon single crystal
A silicon single crystal is produced by a method wherein a silicon plate is inductively heated; granular silicon is melted on the silicon plate; and the molten silicon thus produced flows through a flow conduit in the center of the plate to a phase boundary at which a silicon single crystal crystallizes, wherein a silicon ring having a lower resistivity than the plate, and lying on the plate, is inductively heated prior to inductively heating the plate, and melting the ring.
US09410252B2 Corrosion inhibitor injecting method
A method for injecting a corrosion inhibitor injecting an oxidant and an anticorrosive agent-pH adjusting agent complex including an anticorrosive agent and a pH adjusting agent adsorbed on a surface of the anticorrosive agent into high temperature water in contact with a surface of a metal structural material and irradiating the high temperature water with a radioactive ray or an ultraviolet ray, wherein the anticorrosive agent of the anticorrosive agent-pH adjusting agent complex has, on the surface of the anticorrosive agent, an active site where the pH adjusting agent reacts with the oxidant, and the pH adjusting agent present on the surface of the anticorrosive agent of the anticorrosive agent-pH adjusting agent complex and/or in the high temperature water is oxidized with the oxidant by the irradiation with the radioactive ray or the ultraviolet ray to change pH adjusting ability of the pH adjusting agent and shift a pH of the high temperature water to a neutral side, and thereby deposition of the anticorrosive agent 11 to the metal structural material 65 is accelerated.
US09410244B2 Semiconductor processing apparatus including a plurality of reactors, and method for providing the same with process gas
A semiconductor processing apparatus is described. The semiconductor processing apparatus includes a gas supply system. The gas supply system has at least one gas supply unit including a process gas source, a gas distribution manifold having an annular gas distribution conduit provided with an inlet and valved outlets; and a gas supply conduit fluidly connecting the process gas source to the inlet of the gas distribution manifold. The semiconductor processing apparatus also includes a plurality of reactors, each fluidly connected to a respective valved outlet of the gas distribution manifold, such that process gas from the process gas source of the at least one gas supply unit is selectively suppliable to a respective reactor via the gas supply conduit, the gas distribution manifold, and a respective valved outlet. A method of providing a plurality of reactors with process gas is also described.
US09410242B2 Microwave plasma reactor for manufacturing synthetic diamond material
A microwave plasma reactor for manufacturing synthetic diamond material via chemical vapour deposition, the microwave plasma reactor comprising: a plasma chamber; a substrate holder disposed in the plasma chamber and comprising a supporting surface for supporting a substrate on which the synthetic diamond material is to be deposited in use; a microwave coupling configuration for feeding microwaves from a microwave generator into the plasma chamber; and a gas flow system for feeding process gases into the plasma chamber and removing them therefrom; wherein the microwave plasma reactor further comprises an electrically conductive plasma stabilizing annulus disposed around the substrate holder within the plasma chamber.
US09410240B2 Process for producing metallized multi-layer bodies from special polycarbonates
The invention relates to a process for producing multi-layer bodies which carry at least one metal layer. The invention further relates to multi-layer products having at least three layers, comprising a substrate layer made of a substrate and containing special copolycarbonates, a metal layer and at least one additional layer.
US09410236B2 Sputtering apparatus and method
A sputtering apparatus comprises a chamber configured to contain at least one sputter target and at least one substrate to be coated. The chamber has at least one adjustable shielding member defining an adjustable aperture. The member is positioned between the at least one sputter target and the at least one substrate. The aperture is adjustable in at least one of the group consisting of area and shape.
US09410228B2 Metal matrix composite, and preparation method thereof
The present invention provides a preparation method of a metal matrix composite. The method comprises the following steps of: 1) pulverizing a solid carbon material to a micrometer size; 2) plastic deforming a metal matrix powder and dispersing the pulverized nanometer-sized carbon material into the metal matrix powder during the plastic deformation; 3) integrating the metal/carbon nano-material composite powder obtained in step 2) by using a hot forming process; and 4) heat treating the integrated bulk material at a predetermined temperature to form a composite having a metal-carbon nanophase, a metal-carbon nanoband formed by growth of the metal-carbon nanophase, or a metal-carbon nano-network structure formed by self-coupling of the metal-carbon nanoband.
US09410227B2 Processes for recovering rare earth elements from various ores
The present disclosure relates to processes for recovering rare earth elements from various materials. The processes can comprise leaching the at least one material with at least one acid so as to obtain a leachate comprising at least one metal ion and at least one rare earth element, and a solid, and separating the leachate from the solid. The processes can also comprise substantially selectively removing at least one of the at least one metal ion from the leachate and optionally obtaining a precipitate. The processes can also comprise substantially selectively removing the at least one rare earth element from the leachate and/or the precipitate.
US09410226B2 Ore slurry production method and metal refining method
Disclosed is a method for producing an ore slurry that can suppress a rise in the viscosity of the ore slurry and consequently prevent a failure in transporting the slurry, and also to provide a metal refining method utilizing such a slurry producing method. The present invention includes: a pulverizing/classifying step of pulverizing raw material ores and classifying the resulting ores at a predetermined classifying point so that oversized ore particles are removed so as to obtain a coarse ore slurry composed of undersized ore particles; a grain size measuring step of measuring the grain size of the resulting coarse ore slurry; and an ore slurry condensing step of loading the coarse ore slurry to a solid-liquid separation device and separating and removing moisture contained in the coarse ore slurry therefrom so as to condense ore components.
US09410218B2 Method for operating a blast furnace
A method of operating a blast furnace comprising two or more lances that inject reducing agents from a tuyere including injecting a solid reducing agent and a flammable reducing agent from different lances; and arranging a position of an end of the lance that injects the flammable reducing agent closer to a near side in a injecting direction by more than 0 to 50 mm than a position of an end of the lance that injects the solid reducing agent.
US09410217B2 Method of reducing a fermentation and/or enzyme inhibitor in a saccharide-containing composition
Provided is a method of treating a saccharide-containing composition, the method comprising contacting a composition containing a saccharide with a compound of formula (I) or a salt thereof wherein R1-R4, X, and n are as described herein. Further provided is a composition comprising a saccharide and a compound of formula (I) or a salt thereof.
US09410214B2 Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme A derived compounds
Provided herein are compositions and methods for improved production of acetyl-CoA and acetyl-CoA derived compounds in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding a phosphoketolase (PK), and a functional disruption of an endogenous enzyme that converts acetyl phosphate to acetate. In some embodiments, the host cell further comprises a heterologous nucleotide sequence encoding a phosphotransacetylase (PTA). In some embodiments, the enzyme that converts acetyl phosphate to acetate is a glycerol-1-phosphatase. In some embodiments, the glycerol-1-phosphatase is GPP1/RHR2. In some embodiments, the glycerol-1-phosphatase is GPP2/HOR2. The compositions and methods described herein provide an efficient route for the heterologous production of acetyl-CoA-derived compounds, including but not limited to, isoprenoids, polyketides, and fatty acids.
US09410207B2 Method and compositions for detecting epidermal growth factor receptor variant forms in cancer cells
Method and compositions for screening for the presence of Epidermal Growth Factor Receptor variant 3 (EGFR(v3)) in a sample are described. The method comprises obtaining a sample containing a plurality of cells; hybridizing a set of chromosomal probes to the sample, wherein the set comprises an EGFR(v3)-probe and a probe to chromosome 7 different from an EGFR(v3)-probe; and visualizing the hybridization pattern of the set of chromosomal probes in the plurality of cells of the sample, wherein the presence of at least one copy of chromosome 7 lacking a hybridization signal of the EGFR(v3)-probe in at least one cell is indicative of the presence of the EGFR(v3) in the sample. The method and compositions are suitable for diagnosing the therapeutic outcome for treating a patient having a cancer with an anti-EGFR therapeutic agent and for screening a sample for a predisposition for forming an EGFR-associated cancer.
US09410206B2 Long noncoding RNA (lncRNA) as a biomarker and therapeutic marker in cancer
Long noncoding RNAs (lncRNAs) that may be used as cancer biomarkers and methods of diagnosing, prognosing and monitoring cancer including, but not limited to, cutaneous melanoma using said lncRNAs are provided herein. In some embodiments, the methods include steps of isolating one or more lncRNA transcripts in a biological sample from the subject; measuring a test level of the one or more isolated lncRNA transcripts; comparing the test level to a control level of the one or more lncRNA transcripts; and diagnosing or making a prognosis based on the lncRNA level. In some embodiments, the lncRNA transcript is an linc00340 transcript or variant thereof. These lncRNA transcripts may also be used as a therapeutic target in the treatment of cancer.
US09410204B2 Biomarkers for diagnosing ischemia
The present invention provides methods and compositions for diagnosing and predicting the occurrence of ischemia. For example, the present invention provides methods and compositions for diagnosing and predicting the risk and cause of transient neurological events (TNE) as ischemic or non-ischemic.
US09410200B2 Labelled nucleotides
Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
US09410199B2 Labelled nucleotides
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterized in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
US09410194B2 Compositions, kits and methods for synthesis and/or detection of nucleic acids
A composition comprising a thermostable DNA polymerase; and a PCR inhibitor blocking agent, wherein the PCR inhibitor blocking agent is present in an amount effective to enhance tolerance of an assembled PCR to a PCR inhibitor.
US09410191B2 Method and system for decontaminating materials
Methods, systems, and devices for decontaminating materials containing biological or biologically derived materials, such as microorganisms or DNA products, are provided. The methods, systems, and devices may be used for decontaminating or sterilizing materials, such as surfaces, including, but not limited to reducing the number of viable microorganisms on surfaces. The methods, systems, and devices may further be used for rendering DNA non-amplifiable in nucleic acid amplification reactions that synthesize DNA amplification products.
US09410190B2 Stem accelerated isothermal nucleic acid amplification technology
The invention is in the field of nucleic acid amplification, hi particular, methods are described which utilize stem primers that improve the rapid and specific amplification of a test sample.
US09410184B2 Glucose dehydrogenase
A modified pyrroloquinoline quinone glucose dehydrogenase that exhibits a high selectivity for glucose is provided. A modified pyrroloquinoline quinone glucose dehydrogenase is disclosed in which the amino acid residue G at Position 99 of a pyrroloquinoline quinone glucose dehydrogenase (PQQGDH) represented by SEQ ID NO: 1, or the amino acid residue G at Position 100 of the pyrroloquinoline quinone glucose dehydrogenase (PQQGDH) represented by SEQ ID NO: 3, is substituted by the amino acid sequence TGZN (where Z is SX, S, or N and X is any amino acid residue). The modified PQQGDH of the present invention may additionally comprise one or more mutations selected from the group consisting of Q192G, Q192A, or Q192S; L193X; E277X; A318X; Y367A, Y367F, or Y367W; G451C; and N452X (where X is any amino acid residue).
US09410182B2 Phosphatase coupled glycosyltransferase assay
A kit for detecting or measuring glycosyltransferase activity including a first reagent comprising a phosphatase and a second reagent comprising a free phosphate detector, and method of detecting and measuring glycosyltransferase activity. A sugar donor, an acceptor substrate, a glycosyltransferase enzyme and a phosphatase are combined and the amount of free phosphate present in the product is measured and used to calculate the activity of the glycosyltransferase enzyme.
US09410180B2 Biological sterilization indicator system and method
A biological sterilization indicator (BI) system and method. The system can include a BI and a reading apparatus comprising a well. The BI can include a housing, which can include a first portion, and a second portion movable between a first “unactivated” position and a second “activated” position. The reading apparatus can detect at least one of (i) when the well is empty; (ii) when the biological sterilization indicator is positioned in the well with the second portion of the housing in the first position, and (iii) when the biological sterilization indicator is positioned in the well with the second portion of the housing in the second position. The method can include detecting at least one of the above conditions, which can be used to detect an activation status of the biological sterilization indicator.
US09410179B2 Diagnostic method for the determination of Helicobacter pylori
The present invention relates to a diagnostic method for the determination of Helicobacter pylori in a tissue biopsy comprising the step of incubating a tissue biopsy with an aqueous diagnostic reagent comprising urea and a pH indicator, and determining any pH change, characterized in that said diagnostic reagent comprises a lactone, and that the ratio between the volume of the reagent and the volume of the sample is variable and less than 30.
US09410175B2 Process for microbial production of a valuable compound
The present invention relates to a process for the production of a valuable compound by cultivation of a microorganism comprising cultivating the microorganism in a medium wherein all nutrients are provided in excess over the whole cultivation period and wherein a suitable amount of oxygen is fed to the culture to maintain the culture under conditions of oxygen limitation.
US09410169B2 Process for producing chiral 1- substituted 2-piperidinols employing oxidoreductases
The present invention relates to an enantioselective enzymatic process for the preparation of an optically active 3-hydroxypiperidinecarboxylic acid derivative.
US09410166B2 Alcohol dehydrogenases (ADH) useful for fermentive production of lower alkyl alcohols
The invention relates to suitable candidate alcohol dehydrogenase (ADH) enzymes for production of lower alkyl alcohols including isobutanol. The invention also relates to recombinant host cells that comprise such ADH enzymes and methods for producing lower alkyl alcohols in the same.
US09410165B2 Polypeptides having cellulolytic enhancing activity and nucleic acids encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
US09410160B2 Plant SNF1-related protein kinase gene
The present invention relates to the isolation, purification, characterization and use of the plant Snf1-related protein kinase (SnRK) gene and genetic products. The invention includes isolated and purified SnRK DNA and relates to methods of regulating water loss and plant drought tolerance, sucrose content, starch content, seed oil content, fatty acid synthesis, seed oil acyl composition, seed size/weight, resistance/tolerance to biotic stresses, increased root biomass, and/or carbon flux into other seed components, plant, using the gene, and to tissues and plants transformed with the gene. The invention also relates to transgenic plants, plant tissues and plant seeds having a genome containing an introduced DNA sequence of the invention, and a method of producing such plants and plant seeds.
US09410154B2 HBV treatment
RNA interference (RNAi) agents and the use of the RNAi agents for treating hepatitis B infection in individuals, as well as pharmaceutical compositions containing the RNAi agents are provided. The RNAi agents, or constructs for expressing them are utilized to inhibit expression of at least one Hepatitis B virus (HBV) gene, wherein each agent comprises an effector sequence complementary to or substantially complementary to a predicted sequence transcribed from a target region. In some embodiments of the present invention, the agents have more than one effector sequence; wherein the multiple effectors may target the same region of an HBV gene, different (possibly overlapping) regions of the same gene and/or different HBV genes.
US09410152B2 Use of microrna molecules to influence skin pigmentation
At least one microRNA selected from among hsa-miR-330, hsa-miR-7 and hsa-miR-137, the mature forms thereof, and the precursors thereof, for depigmenting the skin, and an in vitro method for identifying depigmenting compounds, which includes the steps of: a) placing at least one test compound in contact with a sample of melanocytes; b) measuring the expression or activity of at least one microRNA selected from among miR-330, miR-7 and miR-137, the mature forms thereof, and the precursors thereof, in the melanocytes; c) selecting the compounds for which at least 20% activation of the expression or of the activity of at least one of the microRNAs is measured in the melanocytes treated in a) by an element for comparing with the untreated melanocytes.
US09410144B2 Blood cell sorting methods and systems
The invention relates to methods of isolating white blood cells (WBCs) from a sample, e.g., whole blood, using magnetic particles that specifically bind to WBCs and a series of specific steps and conditions. The methods can include one or more of decreasing the viscosity of the sample prior to WBC isolation, agitating the sample at specified frequencies, and/or using a sample container arranged such that all of the sample is placed in close proximity (e.g., within 5, 2, 1, or 0.5 mm) to the source of the magnetic field. The new methods provide for isolation of WBC preparations with high yield, purity, and viability. The methods are designed for compatibility with automation protocols for rapid processing of multiple samples.
US09410142B2 Dendrimer-based excipients for the attenuation of protein aggregation
One aspect of the invention is a salt comprising guanidinium groups, as shown in formula I. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula II. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula III. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula IV. Yet another aspect of the invention is a salt comprising guanidinium groups, as shown in formula I, II, III, and IV further comprising independently for each occurrence citrate, phosphate, or sulfate anion. Also disclosed are compositions comprising a protein and a salt comprising guanidinium groups, as shown in formula I, II, III, and IV. Also provided are methods of increasing shelf life of an aqueous solution of a protein and decreasing the amount of protein aggregation in an aqueous solution of a protein.
US09410139B2 Recombinant adenylate cyclase toxin of bordetella induces T cell responses against tumoral antigens
An immunogenic composition comprising a recombinant protein comprising a Bordetella CyaA, or a fragment thereof, and a peptide that corresponds to a tumor antigen is provided as a cancer treatment. Methods of treatment with this immunogenic composition are also provided. In an embodiment, the therapeutic composition is a treatment for melanoma, and comprises epitopes from the HLA*0201 epitope. These epitopes include Tyr or GnT-V, and are present in the recombinant proteins CyaA-E5-Tyr and CyaA-E5-GnT-V.
US09410133B1 Glucan phosphatase variants for starch phosphorylation
Glucan phosphatase nucleotide or polypeptide variants of the presently-disclosed subject matter can alter the biophysical properties of starch in vitro or in planta, as well as the total starch biomass production in planta as compared to plants expressing wild-type glucan phosphatases. Plants producing the polypeptide variants of the presently-disclosed subject matter can have increased starch accumulation, increased starched biomass, and/or starch having desired biophysical properties. A method of the presently-disclosed subject matter for producing altered starch includes providing a plant that produces a glucan phosphatase polypeptide variant that comprises an amino acid mutation and collecting starch from the plant.
US09410129B2 Recombinant serotype 5 (Ad5) adenoviral vectors
The invention relates to oncolytic adenovirus vectors and their uses in cancer therapy. The adenovirus vectors according to the invention have superior safety properties and have effective therapeutic activity. A production method for the inventive adenoviruses is also disclosed. The adenovirus vectors are useful in cancer therapy.
US09410127B2 Microfluidic apparatus and method of enriching target material in biological sample by using the same
A micro fluidic apparatus includes a sample chamber that divides a sample into a first fluid layer and a second fluid layer due to a centrifugal force; a first enriching unit a that receives the first fluid layer from the sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference; and a second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference.
US09410125B2 Medium for mammalian somatic cells and additive therefor
Disclosed are a medium for mammalian somatic cells with which mammalian somatic cells can be grown effectively when the mammalian somatic cells are cultured, while reducing the amount of serum to be added to the medium as much as possible or without adding serum thereto, and an additive to constitute the medium. By blending of a ligand for an endothelial cell differentiation gene (Edg) family receptor and a ligand for a serotonin receptor to a medium, somatic cells of mammals can be grown even in cases where the medium does not contain serum at all or contains only a small amount thereof.
US09410123B2 Hemangio colony forming cells and non-engrafting hemangio cells
Methods of generating and expanding human hemangio-colony forming cells and non-engrafting hemangio cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells, non-engrafting hemangio cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Human non-engrafting hemangio cells are a novel progenitor cell population that is related to but distinct from the hemangioblast and human hemangio-colony forming cells. The invention also provides compositions, preparations, and solutions comprising hemangio-colony forming cells, non-engrafting hemangio cells or cells differentiated therefrom. The compositions, preparations, and solutions include cryopreserved preparations and substantially purified preparations, as well as mixed compositions formulated in combination with related hemangioblast progenitor cell types that can engraft into the bone marrow.
US09410121B2 Medium comprising transforming growth factor beta 1 and basic fibroblast growth factor
The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
US09410120B2 Composition for embryo culture
Provided is a composition for embryo culture, which contains a constitution suitable for embryo culture. Provided is a composition for embryo culture, which contains (a) a constitution shown in Table A below. TABLE A ComponentsmM L-Alanine0.297 ± 0.089 L-Asparagine0.015 ± 0.005 L-Aspartic acid0.120 ± 0.036 L-Glutamic acid0.550 ± 0.165 Glycine0.979 ± 0.294 L(−)-Proline0.105 ± 0.032 L-Serine0.176 ± 0.053 L(+)-Arginine0.108 ± 0.032 L(−)-Cystine0.048 ± 0.014 L-Histidine0.053 ± 0.016 L(+)-Isoleucine0.036 ± 0.011 L-Leucine0.081 ± 0.024 L(+)-Lysine0.176 ± 0.053 L-Methionine0.022 ± 0.007 L(−)-Phenylalanine0.045 ± 0.013 L(−)-Threonine0.109 ± 0.033 L-Tryptophan0.018 ± 0.005 L-Tyrosine0.048 ± 0.014 L-Valine0.108 ± 0.032 L-Glutamine or0.398 ± 0.119 glutamine derivative Taurine1.412 ± 0.424
US09410119B2 Cell culture device, cell culture system, and cell culture method
To provide a cell culture device, a cell culture system and a cell culture method capable of suppressing fluctuations in pressure in a culture fluid, and suppressing gas bubbles from flowing into a cell culture section. A cell culture device including: a cell culture section that cultures cells; a storage section that stores a culture fluid; flow paths that connect the cell culture section and the storage section; a fluid delivery device that is provided at the flow paths and that delivers the culture fluid from the storage section to the cell culture section; a pressure equalizing unit that is provided at the flow paths and that suppresses fluctuations in pressure imparted to the culture fluid delivered to the cell culture section; and a pressurization unit that is provided at the flow path at a flow outlet side of the cell culture section and that applies a specific pressure to the culture fluid.
US09410117B2 Porphyrin containing lactic acid bacterial cells and use therof
Culturally modified lactic acid bacterial cells containing a porphyrin compound and their use in a novel method of reducing the oxygen content in a food and feed product or starting material is provided and means of improving the shelf life and/or quality of such products by using the culturally modified bacterial cells. Such culturally modified cells are useful in the manufacturing of a food and a feed product and for the manufacturing of metabolites produced by modified cells.
US09410116B2 Method for producing fungus structures
A method for growing organically derived building materials in the form of a moldable substrate that can be engineered to serve a wide range of manufacturing and construction applications is presented. In particular, the embodiments consider a plurality of fungal molded shapes preferably grown from fungal inoculum and mechanically compressed at least once during the growing process as well as integration of structure support members to the fungal structure. The present invention provides a fungal substrate which could be molded, and easily and cheaply preprocessed to precise geometric specifications. The organically derived building materials also incorporate layers of structural reinforcements to improve load bearing and other structural capacities.
US09410114B2 Cell culture methods and devices utilizing gas permeable materials
Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.
US09410113B2 Bioreactor system for three-dimensional tissue stimulator
A bioreactor system for growing and conditioning tissue for research and implantation in a human or animal body is disclosed which includes one or more tissue growth chambers for growing and conditioning tissue, each chamber being defined by a housing and providing a fluid culture media cavity which can act as a reservoir. A construct for growing three-dimensional tissues is housed in each tissue growth chamber. Each chamber is connected to a source of pressurized air for applying a controlled pressure to the chamber media cavity. The tissue growth chambers can be mounted on an agitation device such as a shaker system which enhances mass transport within the chamber media cavity. A control system is provided to control the pressure and temperature of the pressurized gas delivered to the chamber media cavity and subsequently to the tissue construct.
US09410111B2 Cleaning composition that provides residual benefits
A composition for use on a hard surface. The composition has: (i) at least 7.5 wt. % of at least one surfactant selected; (ii) a blend of linear primary alcohols, or a blend of ethoxylated linear primary alcohols, wherein each alcohol of the non-ethoxylated blend or ethoxylated blend includes a carbon chain containing 9-17 carbons; (iii) a transport rate factor of less than about 55 seconds; and (iv) an adhesion time of greater than about 8 hours.
US09410105B2 Lubricant compositions comprising epoxide compounds
A lubricant composition including an epoxide compound is disclosed. An additive package including the epoxide compound is also disclosed. The epoxide compound of the lubricant composition acts to improve compatibility of the lubricant composition with a fluoropolymer seal and improve the total base number of the lubricant composition.
US09410090B2 Method of operating crude treatment system
Crude containing a comparatively large content of nickel, vanadium, or carbon residue is treated so as to supply a raw material to a downstream catalytic cracking process. A primary distillation tower fractionates first crude into a residue fraction partly used as raw oil of a catalytic cracking process and other fractions. A secondary distillation tower fractionates second crude containing a larger content of a catalytic poison with respect to catalysts used in the catalytic cracking process than the first crude into a light fraction included in a distillation temperature range of the other fractions and a heavy fraction as a rest thereof. A light fraction supply line supplies the light fraction to the primary distillation tower so as to be treated in the primary distillation tower.
US09410088B2 Phosphonate-substituted lignin as a flame retardant
Modified lignin having covalently attached phosphorous containing groups and methods for preparing such compounds are described herein. The modified lignin described herein provides a renewable source of flame retardant material.
US09410083B2 Phosphor composition with self-adjusting chromaticity
Disclosed herein are “smart” phosphor compositions capable of regulating the chromaticity of their emission to substantially constant values even with variations in the excitation radiation they receive to induce photoluminescence. One phosphor of the smart composition demonstrates an increase in emission intensity increases as the wavelength of the excitation radiation is increased. The other phosphor shows a decrease in emission intensity with increasing excitation wavelength. Constant chromaticity in this context is defined as a change in CIE x or y coordinate of less than about five percent over a 10 nm range of excitation wavelengths.
US09410082B2 Semiconductor phosphor nanoparticle and light-emitting device including the same
A semiconductor phosphor nanoparticle includes a semiconductor nanoparticle and a first organic compound. An end of the first organic compound is bonded to a surface of the semiconductor nanoparticle, and the other end of the first organic compound is polymerized to form a first inorganic layer.
US09410077B2 Method for preparing ultra-light-weight (ULW) proppant applied on oil and gas wells
A method for preparing an ultra-light-weight (ULW) proppant usable in the oil and gas industry. The method uses silane coupling agent and organic acid to modify silica fume (SF) to obtain modified SF that is lipophilic and hydrophobic. The modified SF is used as inorganic phase, and the polymerizable monomer is used as organic phase, and the organic-inorganic composite microspheres are obtained through suspension polymerization. The ULW proppant is obtained by drying, screening, and pre-oxidization of the composite microsphere. The ULW proppant has a density of about 1.109 g/cm3-1.278 g/cm3, which is close to that of water, a crushing rate of <5% at 52 Mpa, and a crushing rate of <7% at 69 Mpa. In the oil and gas industry application, water or salt water can be used to replace the high viscose guanidine gum as carrier, thus reduced cost of fracturing, and reduced environment pollution.
US09410076B2 Wellbore servicing methods and compositions comprising degradable polymers
A method of servicing a wellbore comprising providing a degradable polymer and a delayed action construct within a portion of a wellbore, a subterranean formation or both; wherein the delayed action construct comprises (i) a degradation accelerator comprising an alkanolamine, an oligomer of aziridine, a polymer of azridine, a diamine, or combinations thereof, (ii) a solid support, and (iii) an encapsulating material; and placing the wellbore servicing fluid comprising the degradable polymer and delayed action construct into the wellbore, the subterranean formation or both.
US09410074B2 Compositions and methods for inhibiting naphthenate solids formation from liquid hydrocarbons
The present invention relates to a composition and method for inhibiting the formation of naphthenate solids in a liquid hydrocarbon. The method includes contacting a composition including a rosin amine having a formula (I): or (II): where formula (AA): represents a single or double bond; R1, R2 and R5 each independently represent H, alkyl, alkenyl or an alkynyl group each having between one and ten carbon atoms, —(R3O)nR4 wherein R3 is an alkyl group having 1 to 3 carbon atoms and R4 is H, alkyl, alkenyl or an alkynyl group each having between one and ten carbon atoms; n is an integer between 5 and 50; X is a halide, sulphate, phosphate or acetate ion; and a demulsifier intermediate with the liquid hydrocarbon.
US09410072B2 Cement retarder and method of using the same
The reaction product of a polyhydroxy compound and borax is used as a cement retarder for slurries introduced into a wellbore. The molar ratio of the polyhydroxy compound to boron, derived from the borax, is from 1:1 to about 4:1. The polyhydroxy compound may be a sugar such as a gluconic acid, gluconate or glucoheptonate or a salt thereof.
US09410061B2 Tackifier and modified starch formulation, system and method
This disclosure describes formulations, systems and methods for a novel tackifier. The novel tackifier is composed of a modified starch and an acrylamide.
US09410058B2 Compositions and methods for water-resistant gypsum fiber products
A water-resistant gypsum fiber product comprising siloxane and coated with a coating comprising alkali metal organosiliconate is provided. A method of making a gypsum fiber product in which siloxane is cross-linked at the surface of the product is also provided. A fuel-efficient method for making the product and reducing the amount of siloxane dust released is provided as well.
US09410057B2 Coated carbon fiber reinforced plastic parts
Carbon fiber reinforced plastic parts are advantageously coated with powder coating formulations comprising certain red-shifted hydroxyphenylbenzotriazole ultraviolet light absorbers (UVAs). The benzotriazole UVAs are of formulae (I) or (II) The coated carbon fiber reinforced plastic parts are suitable in aerospace applications, automotive parts and sporting goods.
US09410056B2 Flame retardant coating
A flame retardant coating is disclosed. The flame retardant coating comprises polyurea elastomer, spray processable graphite, a graphite stabilizer agent, and a flame retardant. A method of manufacturing a flame retardant polyurea elastomer coating is also disclosed. A two part polymerizable system is provided comprising a first part containing isocyanates, and a second part containing polyamines. At least one of the first part and the second part contains a flame retardant, and both of spray processable graphite and a graphite stabilizer agent. The first part and the second part are then mixed to form the flame retardant polyurea elastomer coating.
US09410053B2 Aqueous coating composition and anti-glare coating formed thereform
Provided is an aqueous coating composition including: particular amounts of certain first solid polymeric particles having an average diameter of 0.60-0.99 μm; certain second solid polymeric particles having an average diameter of 2-20 μm, and mixtures thereof; and, third solid polymeric particles having a calculated Tg of from −60 C to 120° C. and an average particle diameter of from 50 nm to 500 nm; wherein the second solid polymeric particles have a K10 value of less than 1.9E+10 N/m2; wherein the difference between the refractive index of the outer surface of the second solid polymeric particles and the refractive index of the third solid polymeric particles is between 10E-4 to 10E-2; and wherein the aqueous coating composition comprises less than 10% by volume, inorganic extender particles. A method for providing a coating from the aqueous coating composition and a low glare coating so formed are also provided.
US09410051B2 Hot melt inks
This disclosure includes a hot melt ink composition that includes at least one wax having a freezing point of from about 20° C. to about 45° C. and a melting point of at least about 35° C., and at least one colorant. The composition includes at least about 50 wt % of the at least one wax. This disclosure also relates to a printing process using such a composition and a product containing such a composition.
US09410049B2 Single phase water based energy curable polymers and method of preparing coatings and printing inks
Single phase, water based, energy curable compositions and a method of preparing coatings and printing inks from same.
US09410047B2 Antifouling article and method for producing same
An antifouling article characterized by having a cured condensed coating film of a perfluoropolyether group-containing silane represented by general formula [1] on the surface of a substrate and by having a fluorine concentration of the cured condensed coating film of 0.2-2.0 μg/cm2.
US09410045B2 Antifouling paint system
A coated substrate having an epoxy coating. The epoxy coating contains 4,5-dichloro-2-n-octylisothiazolin-3-one.
US09410044B2 Boron-containing linking agents
Embodiments of the invention include linking agents including borate, borazine, or boronate groups and coatings and devices that incorporate such linking agents, along with related methods. Other embodiments are also included herein.
US09410042B2 Process for obtaining carbon black powder with reduced sulfur content
The present disclosure relates to a process for obtaining carbon black powder with a sulfur content of less than 0.07%. The process includes step of reacting carbon black powder with a sulfur content of 1-2% with an alkali metal or salt thereof, in a fluid media, at a temperature in the range of 100° C. to 350° C. and pressure in the range of 10 to 500 psig. It is found that in accordance with the process of the present disclosure, the sulfur content was reduced substantially from that of about 1.25% to that of 0.05%, resulting in about 96% desulfurization.
US09410038B2 Compound, ink, ink cartridge and ink jet recording method
There are provided a new compound which has the following general formula (1) and which is useful as a coloring material, an ink containing the compound, an ink cartridge containing the ink and an ink jet recording method including ejecting the ink from a recording head of an ink jet system to record an image on a recording medium.
US09410033B2 Rubber composition for undertread, and pneumatic tire
The present invention provides a rubber composition for an undertread, which has improved in processability, fuel economy, and tensile properties in a balanced manner, and also provides a pneumatic tire formed from the rubber composition. The present invention relates to a rubber composition for an undertread, including: a rubber component containing a modified natural rubber having a phosphorus content of 200 ppm or less; and carbon black and/or a white filler, wherein the modified natural rubber is contained in an amount of 5% by mass or more per 100% by mass of the rubber component.
US09410032B2 Composition for a starch container, starch container using same, and method for manufacturing the starch container
Provided is a composition for a starch container, comprising: 20 to 60 weight % of an undenatured starch; 5 to 30 weight % of a pulp fiber powder; 0.1 to 2 weight % of a photocatalyst; 0.5 to 5 weight % of a release agent; and 0.01 to 5 weight % of a capsule type blowing agent preparations; and the remainder being a solvent. Also provided is a starch container using the composition. The above-described composition of the present invention may be used not only as a material for a disposable container which has improved blowing property, and which is lightweight and has improved moldability, but also as a material for an eco-friendly starch container having eco-friendly characteristics.
US09410029B2 Blends of polyesters containing cyclobutanediol with fluoroalkyl additives and devices made thererom
This invention relates to polymer compositions comprising: (I) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: i) 70 to 100 mole % of terephthalic acid residues; ii) 0 to 30 mole % of aromatic dicarboxylic acid residues having up to 20 carbon atoms; and iii) 0 to 10 mole % of aliphatic dicarboxylic acid residues having up to 16 carbon atoms; and (b) a glycol component comprising 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues, wherein the total mole % of the dicarboxylic acid component is 100 mole %, the total mole % of the glycol component is 100 mole %; and wherein the inherent viscosity of the polyester is from 0.1 to 1.2 dL/g as determined in 60/40 (wt/wt) phenol/tetrachloroethane at a concentration of 0.5 g/100 ml at 25° C.; and (II) at least one fluoroalkyl derivative.
US09410028B2 Process for preparing polyacrylates
Process for preparing polyacrylates, by the free-radical polymerization of monomer mixtures comprising at least 70% by weight of at least one acrylic and/or methacrylic ester in the presence of amino acids as regulator substances, and reaction solution comprising one or more solvents and one or more monomers, at least 50% by weight of the solvents being organic solvents, and at least 70% by weight of the monomers being acrylic and/or methacrylic esters, with at least one amino acid being present.
US09410025B2 Polyolefin-based resin expanded beads comprising inorganic fillers
An inorganic filler-containing, polyolefin-based resin expanded bead having an expanded core layer of a first polyolefin-based resin, and a cover layer of a second polyolefin-based resin that covers the expanded core layer, wherein a weight ratio of the cover layer to the expanded core layer is 1:99 to 20:80, the expanded core layer contains an inorganic filler in a weight percentage amount of 5 to 90%, and the cover layer contains no inorganic filler or contains an inorganic filler in a weight percentage amount lower than that in the expanded core layer.
US09410024B2 Azeotrope-like compositions comprising 1-chloro-3,3,3-trifluoropropene
An azeotrope-like mixture consisting essentially of a binary azeotrope-like mixture consisting essentially of trans-1-chloro-3,3,3-trifluoropropene (trans-HFO-1233zd) and a second component selected from the group consisting of 2,3,3,3-tetrafluoropropene (HFO-1234yf) and trans-1,3,3,3-tetrafluoropropene (trans-HFO-1234ze), and combinations of these and various uses thereof.
US09410023B2 Protective film for polarizing plate and polarizing plate using the same
There are provided a protective film for a polarizing plate, wherein the protective film comprises a stretched film comprising a (meth)acryl-based resin and having an absolute value of a planar orientation coefficient ΔP of less than or equal to 2.5×10−4, and a polarizing plate comprising a polarizing film, and the protective film for a polarizing plate laminated on at least one surface of the polarizing film via an adhesive layer. The stretched film can be, for example, a biaxially stretched film.
US09410022B2 Sheetlike structure or shaped article comprising latent heat storage media
The invention provides methods for producing sheetlike structures or shaped articles that comprise latent heat storage media, characterized in that mixtures comprising one or more microcapsules which contain one or more latent heat storage media, and one or more polymers based on one or more ethylenically unsaturated monomers selected from the group consisting of vinyl esters, (meth)acrylic esters, vinylaromatics, olefins, 1,3-dienes and vinyl halides, are processed by means of thermoplastic shaping techniques.
US09410021B2 Method for producing surface-modified fluororesin film/thermoplastic resin composite
The present invention aims at providing a composite of a surface-modified fluororesin film and a thermoplastic resin bonded to each other, and medical equipment containing the composite. A method for producing a fluororesin/thermoplastic resin composite includes roughening a surface of a fluororesin film by ion beam irradiation from an ion source, and pressure-bonding the surface-modified fluororesin film obtained in the surface roughening step and a thermoplastic resin while maintaining the thermoplastic resin in a fluid state.
US09410017B2 Poly-amic acid, photo-sensitive resin composition, dry film, and circuit board
The present invention relates to a novel polyamic acid introduced with an imidazolyl group in the polymer chain, a photosensitive resin composition including the polyamic acid and that is capable of providing a photosensitive material that satisfies the characteristics of an excellent bending property and low stiffness and also exhibits excellent heat resistance and coating resistance, a dry film obtained from the photosensitive resin composition, and a circuit board including the dry film.
US09410014B2 Polymer manufacturing process
Embodiments relate to a relatively rapid transesterification process including transesterifying condensation polymers such as polyethylene terephthalate (PET), or other polyesters used in commerce, with a modifying monomer mix containing other monomers to manufacture new polymers containing the pre-condensed moieties. The process preferably only involves transesterification as a reaction mechanism. The process preferably produces a rapid buildup of molecular weight and/or polymer uniformity by the high temperature transesterification of the condensation polymer with the modifying monomer mixture. The process can be performed in any suitable vessel including an extrusion line, and it has the advantage of greatly reduced cycle times over currently used condensation polymer utilization processes such as the recycling of PET into other materials.
US09410009B2 Catalyst composition comprising shuttling agent for tactic/ atactic multi-block copolymer formation
Copolymers, especially multi-block copolymer containing therein two or more segments or blocks differing in tacticity, are prepared by polymerizing propylene, 4-methyl-1-pentene, or another C4-8 α-olefin in the presence of a composition comprising the admixture or reaction product resulting from combining: (A) a first metal complex olefin polymerization catalyst, (B) a second metal complex olefin polymerization catalyst capable of preparing polymers differing in tacticity from the polymer prepared by catalyst (A) under equivalent polymerization conditions, and (C) a chain shuttling agent.
US09410006B2 Fluorine-containing highly branched polymer and resin composition containing the same
It is an object to provide a compound that can provide a molded article and a coating film excellent not only in solubility in an organic solvent, but also in miscibility with/dispersibility in a matrix resin, causing no aggregation in a matrix resin, excellent in surface modification property, and having high transparency. A fluorine-containing highly branched polymer obtained by polymerizing a monomer A having two or more radical polymerizable double bonds in the molecule thereof with a monomer B having a fluoroalkyl group and at least one radical polymerizable double bond in the molecule thereof in the presence of a polymerization initiator C in a content of 5% by mol or more and 200% by mol or less, based on the total molar amount of the monomer A and the monomer B; and a resin composition comprising the polymer.
US09409998B2 Method and apparatus for processing fibril cellulose and fibril cellulose product
A method for processing fibril cellulose which is in the form of aqueous fibril cellulose gel includes lowering the pH of the aqueous fibril cellulose gel to provide aqueous fibril cellulose gel of reduced water retention capacity, and dewatering the aqueous fibril cellulose gel of reduced water retention capacity to provide dewatered fibril cellulose. The dewatering is performed by pressure filtration.
US09409990B2 Methods of inhibiting tumor growth by antagonizing IL-6 receptor
The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-6 antagonist may be, e.g., an antibody that specifically binds IL-6R. The IL-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.
US09409989B2 Method for making multispecific antibodies having heteromultimeric and common components
The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin chimeras. The invention also relates to the heteromultimers prepared using the method. Generally, the method provides a multispecific antibody having a common light chain associated with each heteromeric polypeptide having an antibody binding domain. Additionally the method further involves introducing into the multispecific antibody a specific and complementary interaction at the interface of a first polypeptide and the interface of a second polypeptide, so as to promote heteromultimer formation and hinder homomultimer formation; and/or a free thiol-containing residue at the interface of a first polypeptide and a corresponding free thiol-containing residue in the interface of a second polypeptide, such that a non-naturally occurring disulfide bond is formed between the first and second polypeptide. The method allows for the enhanced formation of the desired heteromultimer relative to undesired heteromultimers and homomultimers.
US09409986B2 IL-1 binding proteins
Proteins that bind IL-1α and IL-1β are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-1-related disorders and for detecting IL-1α and IL-1β in cells, tissues, samples, and compositions.
US09409983B2 Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases
The present invention concerns methods and compositions involving inhibitors of Pre-B Cell Colony Enhancing Factor (PBEF) for inflammatory conditions and diseases, including acute lung injury (ALI), ventilator-induced lung injury (VILI), and acute respiratory distress syndrome (ARDS). The present invention also concerns biomarkers for inflammation as well as methods for screening for PBEF inhibitors.
US09409982B2 Antibody composition-producing cell
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependant cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
US09409980B1 Methods for treating patients with complement-associated disorders with high concentration formulations of anti-C5 antibodies
The present disclosure relates to, inter alia, stable aqueous solutions comprising a high concentration of an antibody that binds to human complement component C5 and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders (for example, age-related macular degeneration or rheumatoid arthritis) using the solutions. Also featured are therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
US09409978B2 Modulation of midbody derivatives
The number of midbody derivatives in a cell may be modulated by modulating autophagy induced by NBR1. Exemplary methods include modulating the amount or activity of NBR1 in the cell, potentiating or inhibiting binding between NBR1 and Cep55 in the cell, or modulating the amount of Cep55 in the cell. These methods can be used in the treatment of cancers or in methods of reprogramming cells.
US09409975B2 Antibody binding microbial heparin binding motif to retard or prevent microbial biofilm formation on implanted medical devices
Methods and reagents for ameliorating biofilm formation on a surface of an indwelling or implanted device in a patient resulting in decreased virulence of microorganisms such as Candida species and/or Staphylococcus species.
US09409966B2 Glucagon-like peptide-1 derivatives and their pharmaceutical use
The invention relates to protracted Glucagon-Like Peptide-1 (GLP-1) derivatives and therapeutic uses thereof. The GLP-1 derivative of the invention comprises a modified GLP-1(7-37) sequence having a total of 2-12 amino acid modifications, including Glu22 and Arg26, and being derivatised with an albumin binding residue or pegylated in position 18, 20, 23, 30, 31, 34, 36, 37, or 39. These compounds are useful in the treatment or prevention of diabetes type 2 and related diseases. The compounds are potent, stable, have long half-lives, a high affinity of binding to albumin, and/or a high affinity of binding to the extracellular domain of the GLP-1 receptor (GLP-1R), all of which is of potential relevance for the overall aim of achieving long-acting, stable and active GLP-1 derivatives with a potential for once weekly administration.
US09409965B2 Kidney-specific tumor vaccine directed against kidney tumor antigen G-250
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers expressing a G250 antigenic marker. Preferred immunogenic agents comprise a chimeric molecule comprising a kidney cancer specific antigen (G250) attached to a granulocyte-macrophage colony stimulating factor (GM-CSF). The agents are useful in a wide variety of treatment modalities including, but not limited to protein vaccination, DNA vaccination, and adoptive immunotherapy.
US09409964B2 Rationally designed antibodies
Antibodies or fragments thereof having CDR regions replaced or fused with biologically active peptides are described. Flanking sequences may optionally be attached at one or both the carboxy-terminal and amino-terminal ends of the peptide in covalent association with adjacent framework regions. Compositions containing such antibodies or fragments thereof are useful in therapeutic and diagnostic modalities.
US09409962B2 Methods and compositions for expressing functional class XIV myosin
The invention, in part, includes methods and compounds useful to prepare and functional class XIV myosin. Functional class XIV myosin prepared using methods of the invention may be useful to screen for and identify compounds that inhibit and treat parasitic infections and contamination.
US09409961B2 Cell penetrating peptides to target EIF4E
The present invention provides compounds to disrupt the eIF4E-eIF4G interaction and pharmaceutically acceptable salts of such compounds. Generally, the compounds are cell-penetrating peptides which bind mammalian initiation factor eIF4E (CPP-eIF4E), wherein the peptide comprises an amino acid sequence selected from the group consisting of SEQ ID NOS: 7, 9-11, 12-26, 27-44 and 45-51. More preferably, the amino acid sequence comprises at least 9 to about 40 amino acids and the mammalian initiation factor eIF4E is human initiation factor eIF4E.
US09409960B2 Bis-met histones
The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
US09409950B2 Linker peptides and polypeptides comprising same
The invention is based, at least in part, on the finding that linker peptides which lack the amino acid sequence GSG reduce or eliminate the addition of posttranslational modifications to the polypeptides which comprise them. More specifically, the novel linker peptides disclosed herein reduce the ability of enzymes to link carbohydrate adducts to polypeptides comprising these linker peptides, e.g., reduce the ability of xylosyltransferase to link xylose to polypeptides. These novel linker peptides, molecules comprising same, and methods of their use are described.
US09409947B2 Method for producing a recombinant peptide and resultant peptide
The invention relates to peptides with the following general formula: A-Thr-Lys-Pro-B-C-D-X, where: A—0, Met, Met (O), Thr, Ala, His, Phe, Lys, Gly B—0, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg C—0, Arg, Phe, Tyr, Gly, His, Pro, Lys D—0, Val, Gly, Tyr, Trp, Phe, His X—OH, OCH3, NH2, where 0 is no amino acid residue, provided that if A≠0, then B and/or C and/or D≠0, if B≠0, then C and/or D≠0, excluding the peptides Phe-Thr-Lys-Pro-Gly (SEQ ID NO: 1), Thr-Lys-Pro-Pro-Arg (SEQ ID NO: 2), Thr-Lys-Pro-Arg-Gly (SEQ ID NO: 3).
US09409944B2 Compositions and methods for inhibiting proteases
In particular, in alternative embodiments, the invention provides pharmaceutical compounds and formulations comprising a family of epoxyketone compounds, which include racemic mixtures or racemates, isomers, stereoisomers, diastereoisomers, derivatives and analogs, and methods for making and using them. In alternative embodiments, pharmaceutical compositions and formulations of the invention are administered to an individual in need thereof in an amount sufficient to treat, prevent, reverse and/or ameliorate an infection, disease or condition that can be ameliorated, treated, prevented or reversed by partially or completely inhibiting a chymotrypsin-like protease or a proteasome activity, including e.g., a retroviral infection such as human immunodeficiency virus-1 (HIV-1) infection, an immune disorder, a neurodegenerative disease or condition, or a cancer such as a myeloma or multiple myeloma, an adenocarcinoma such as a lung adenocarcinoma, a pancreatic cancer, a B-cell related cancer, and lymphomas such as non-Hodgkin's lymphoma.
US09409939B2 Quantification method for remaining liver function and novel liver receptor imaging agent
A test indicator for quantifying remaining liver function is provided. A novel liver receptor imaging agent with liver targeting property is utilized to develop a method for quantifying remaining liver function to serve as test indicator for judging the liver failure outcome in clinic, particularly for judging the necessity of liver transplantation for patients with liver failure or liver disease. The radioactivity uptake of the test indicator was negatively correlated with the extent of liver reserve. The cutoff value of liver reserve for liver transplantation is also disclosed.
US09409937B2 Family of analogues and NADP+ or NADPH, their preparation and their application in therapeutics
A new family of analogues of NADP+ or NADPH, their preparation and their application in therapeutics.
US09409935B2 Control of N-(phosphonomethyl)iminodiacetic acid conversion in manufacture of glyphosate
This invention relates to the preparation of N-(phosphonomethyl)glycine (“glyphosate”) from N-(phosphonomethyl)iminodiacetic acid (“PMIDA”), and more particularly to methods for control of the conversion of PMIDA, for the identification of reaction end points relating to PMIDA conversion and the preparation of glyphosate products having controlled PMIDA content.
US09409932B2 Silicone-compatible photoinitiators
Compounds useful as a photoinitiator and/or photosensitizer represented by the following formula (I): wherein R1 and R2 each independently designates an alkyl group of 1 to 12 carbon atoms or a cycloalkyl group of 5 or 6 carbon atoms or R1 and R2 form together with the carbon atom to which they are attached a cycloaliphatic ring of 5 or 6 carbon atoms, Si* represents an organopolysiloxane residue bonded via a silicon atom of this residue to the oxygen shown in formula (I), or a silane group SiR4R5R6, wherein R4, R5 and R6 each independently designates an alkyl group of 1 to 12 carbon atoms, a cycloalkyl group of 5 or 6 carbon atoms or an aryl group of 6 to 10 carbon atoms, and R3 designates a hydrogen atom or a group represented by the following formula (II) wherein R7 and R8 each independently designates an alkyl group of 1 to 12 carbon atoms or a cycloalkyl group of 5 or 6 carbon atoms or R7 and R8 form together with the carbon atom to which they are attached a cycloaliphatic ring of 5 or 6 carbon atoms, and Si** represents an organopolysiloxane residue bonded via a silicon atom of this residue to the oxygen shown in formula (II), or a silane group SiR9R10R11, wherein R9, R10 and R11 each independently designates an alkyl group of 1 to 12 carbon atoms, a cycloalkyl group of 5 or 6 carbon atoms or an aryl group of 6 to 10 carbon atoms.
US09409931B1 3-O-acyl-ingenol analogues
The present invention relates to a compound according to formula I wherein R1 represents hydrogen, R2 represents hydroxyl and R3 represents hydroxyl; or R1 represents methyl, R2 represents hydroxyl and R3 represents hydrogen; or R1 represents methyl, R2 represents hydrogen and R3 represents hydroxyl; or R1 represents methyl, R2 represents hydrogen and R3 represents hydrogen; or pharmaceutically acceptable hydrates or solvates thereof. The invention further relates to said compounds for use as a medicament, to pharmaceutical compositions comprising said compounds, to methods of treating diseases with said compounds and to intermediates for the preparation of said compounds.
US09409928B2 Aggregation induced emission active cytophilic fluorescent bioprobes for long-term cell tracking
Fluorescent bioprobes comprising luminogen formed nanoparticles comprising luminogens with aggregation-induced emission (AIE) properties, which can be used for long-term cell tracking. The luminogens are nonemissive in organic solution but become highly emissive when aggregated in aqueous solution. The fluorescent molecules can readily pass through cell membranes, stain only the cell cytoplasm, and form highly emissive nanoaggregates in aqueous media without any obvious cytoxicity in the living cells. Furthermore, the molecules can be retained inside the cells without noticeable leakage to the outside. Therefore, these AIE-based compounds can be used as selective and cell-compatible fluroescent bioprobes for long-term live cell tracking and imaging.
US09409927B2 Super lewis acidic borate esters as 18F-labeled PET probes
Compounds having a 1-bora-1-fluoro-2,6,7-trioxabicyclo[2.2.2]octane moiety wherein the fluorine is 18F are described. Also described are reagents for radiolabeling a molecule having Formula I. Method for radiolabeling molecules with the disclosed reagents are also descried, as are radiolabeled molecules prepared thereby.
US09409918B2 Bridged bicyclic piperidine derivatives and methods of use thereof
The present invention relates to Bridged Bicyclic Piperidine Derivatives, compositions comprising a Bridged Bi-cyclic Piperidine Derivative, and methods of using the Bridged Bicyclic Piperidine Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.
US09409915B2 Substituted aza-bicyclic imidazole derivatives useful as TRPM8 receptor modulators
The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold.
US09409912B2 Process for the preparation of sitagliptin phosphate
The present invention relates to a method for the preparation of sitagliptin phosphate and sitagliptin phosphate anhydrous of Formula (I′) and monohydrate of Formula (I),
US09409911B2 Inhibitors of bruton's tyrosine kinase
Disclosed herein are compounds, including compounds having the structure of Formula (A), (B), (C), and (D), as described in further detail herein, that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
US09409907B2 Inhibitor compounds
The present invention relates to compounds of formula I wherein R1, R4, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
US09409905B2 Antibacterial compounds and methods for use
The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.
US09409904B2 Compounds and compositions for use in augmentation of glucose
The present invention is directed to compounds such as: formula wherein linker is independently selected from the group consisting of —S—, —S—S—, —S—(CH2)n-, —NH—, —NH—(CH2)n-, —O—, —SO2-, arylene, heteroarylene; R1 is selected from the group consisting of straight or branched C4-C20 alkyl, straight or branched C4-C20 alkenyl, straight or branched C4-C20 alkynyl, each optionally interrupted with at least one NH, C5-C7 saturated cycloalkyl or heteroalkyl ring, C5-C12 aromatic or heteroaromatic ring, each optionally substituted with at least one group selected from —COOH, —NH2, C1-C8 alkoxy, C1-C5 amidyle, C1-C5 carboxyl, halogen; and R2 is independently selected from the group consisting of H, OH, SH, NH2, NO2, halogen, CN, C1-C8 alkoxy, C1-C5 carboxylic acid, straight or branched C1-C8 alkyl, straight or branched C2-C10 alkenyl, straight or branched C2-C12 alkynyl each optionally substituted by at least one substituent selected from the group consisting of C1-C5 alkoxy, C1-C5 carboxylic acid, OH, SH, NH2, halogen; and compositions for use in the treatment of diabetes and related disorders.
US09409903B2 Benzyl substituted triazine derivatives and their therapeutical applications
The invention provides triazine compounds and methods of their use to modulate protein kinases and to treat diseases mediated by said protein kinases.
US09409902B2 Modulators of HEC1 activity and methods therefor
Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Especially preferred compounds disrupt Nek2/Hec1 binding and are therefore useful as chemotherapeutic agent for neoplastic diseases.
US09409901B2 Compositions and methods for treating or preventing diseases or disorders associated with misregulated EIF4E
Disclosed herein are compounds, compositions, formulations, kits and methods of treatment useful for treating or preventing one or more hyperproliferative disorders, e.g., cancer or a neurological disease or disorder.
US09409895B2 Autotaxin inhibitors
The present invention relates to novel compounds that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in diseases and disorders mediated by autotaxin.
US09409891B2 Solid forms of an antiviral compound
Crystalline solid forms and the amorphous form of the anti-HCV compound 5-(3,3-dimethylbutyn-1-yl)-3-[(cis-4-hydroxy-4-{[(3S)-tetrahydrofuran-3-yloxy]methyl}cyclohexyl){[(1R)-4-methylcyclohex-3-en-1-yl]carbonyl}amino]thiophene-2-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
US09409883B2 Materials for organic electroluminescent devices
The present invention relates to coordination compounds which are used in an electron-transport layer in electronic devices, to ligands, and to the use thereof for the preparation of metal complexes, to a layer, and to an electronic device which comprise the compounds according to the invention, and to a process for the preparation of the compounds according to the invention.
US09409880B2 Modulators of TLR3/dsRNA complex and uses thereof
The present invention provides compounds and compositions that can modulate formation of Toll-like receptor 3 (TLR3) and double-stranded RNA (dsRNA) complex, and methods for using the same. In particular, some aspects of the invention provide compounds of the formula: compositions comprising and methods for using the same, where n, Ar1, Ar2, X1, X2, X3, Z1, and Z2 are those defined herein.
US09409873B2 CDKI pathway inhibitors and uses thereof
The invention relates to the compounds and methods for inhibiting the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to compounds and methods for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases.
US09409871B2 Pyridazinyl derivatives as SMO inhibitors
The present invention relates to compounds of formula I: in which L, W, X, Y, Z, m, p, R1, R2, R3, R4 and R7 are defined in the Summary of the Invention; capable of inhibiting the Hedgehog and Smo signaling pathway. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the diagnosis and treatment of pathologies relating to the Hedgehog and Smo signaling pathway, for example, tumor formation, cancer, neoplasia and non-malignant hyperproliferative disorders.
US09409866B2 Pyridine-2-amides useful as CB2 agonists
The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 agonist and can be used as an active ingredient in a medicament.
US09409859B2 Substituted diphenyl derivatives
Triazene-substituted diphenyl derivatives are suitable as chemotherapeutic agents for treating carcinomas in humans and animals.
US09409858B2 Selective histone deactylase 6 inhibitors
Disclosed are selective histone deactylase inhibitors (HDACi) that having Formula (I). Methods of making and using these inhibitors for the treatment of cancer, in particular melanoma are also disclosed.
US09409848B2 Processes for producing acetic acid
Processes for the reduction and/or removal of permanganate reducing compounds (PRC'S) formed by the carbonylation of methanol in the presence of a Group VIII metal carbonylation catalyst to produce acetic acid are disclosed. More specifically, processes for reducing and/or removing PRC's or their precursors from intermediate streams during the formation of acetic acid by said carbonylation processes are disclosed. In particular, processes in which a low boiling overhead vapor stream from a light ends column is subjected to a distillation to obtain an overhead that is subjected to an extraction to selectively remove and/or reduce PRC's from the process is disclosed. The processes include steps of recycling one or more return streams derived from the distillation step and/or the extraction step to a light ends column and/or a drying column in order to improve water control in the overall reaction system.
US09409847B2 Catalyst for single step conversion of glycerol to acrylic acid and process for the preparation thereof
The present invention provides a process and a solid catalyst for oxydehydration of glycerol to acrylic acid with H2O2 under mild experimental condition at atmospheric pressure. The process provides a single step liquid phase selective oxidation glycerol to acrylic acid over nanocrystalline Cu supported α-MnO2 catalyst. The process provides glycerol conversion of 20-78% and selectivity of acrylic acid up to 86%.
US09409845B2 Alpha-(3,5-dimethoxybenzylidene)-alpha′-hydrocarbyl methylene cyclic ketone and preparation method thereof
The present invention discloses a α-(3,5-dimethoxybenzylidene)-α′-hydrocarbyl methylene cyclic ketone with the following formula: wherein R is aryl or alkyl, its preparation method is: the cyclic ketone blended with morpholine are subjected to azeotropic dehydration to give enamine, the enamine is condensed with 3,5-dimethoxybenzaldehyde and then condensed with alkyl or aryl formaldehyde under acidic or basic conditions to give the product, the present invention further discloses an antitumor agent comprising α-(3,5-dimethoxybenzylidene)-α′-hydrocarbyl methylene cyclic ketone or medically acceptable salts and pharmaceutically acceptable carriers thereof. Through the above, the present invention providesα-(3,5-dimethoxybenzylidene)-α′-hydrocarbyl methylene cyclic ketone and preparation method thereof, the said compound is a high activity antitumor agent obtained by piecing and modifying the formulas of natural anti-tumor active ingredient resveratrol and curcumin, which has a good inhibitory effect on epidermal growth factor receptor.
US09409841B2 Process and apparatus for making phenol and/or cyclohexanone
A process for producing phenol and/or cyclohexanone by cleaving cyclohexylbenzene hydroperoxide in a loop cleavage reactor comprising multiple reaction zones connected in series. In desirable embodiments, fresh cyclohexylbenzene hydroperoxide feed(s) are supplied to reaction zones the final reaction zone, and fresh acid catalyst is supplied only to the final reaction zone. In desirable embodiments, a portion of the effluent exiting the final reaction zone is recycled to the first reaction zone. Each reaction zone is equipped with a heat exchanger downstream of the feed port to extract heat generated from the cleavage reaction.
US09409833B2 Ligand compound, catalyst system for olefin oligomerization, and method for olefin oligomerization using the same
This disclosure relates to a novel ligand compound that can oligomerize ethylene with high catalyst activity and selectivity, a catalyst system for olefin oligomerization including the same, and a method for olefin oligomerization using the same.
US09409832B2 Catalytic dehydration of alcohols using non-volatile acid catalysts
A catalytic process for dehydration of an aliphatic C2-C6 alcohol to its corresponding olefin is disclosed. The process continuously flows through a reaction zone a liquid phase containing an aliphatic C2-C6 alcohol to contact a non-volatile acid catalyst at a reaction temperature and pressure to at least partially convert the aliphatic C2-C6 alcohol in the liquid phase to its corresponding olefin. The reaction pressure is greater than atmospheric pressure and the reaction temperature is above the boiling point of the olefin at reaction pressure, but below the critical temperature of the alcohol, and the olefin product is substantially in the gaseous phase. After the contacting step, the olefin containing gaseous phase is separated from the liquid phase. The invention also relates to catalytic processes such as a hydrolysis of an olefin to an alcohol, an esterification, a transesterification, a polymerization, an aldol condensation or an ester hydrolysis.
US09409830B1 Non-toxic primer mix
A non-toxic primer mix in which DBX-1 (copper(I) 5-nitrotetrazole) acts as the primary explosive portion of the primer. Furthermore, in this mix, boron carbide (B4C) replaces the traditional frictionator/fuel, toxic antimony trisulfide. In addition, potassium nitrate replaces the toxic barium nitrate (BaNO3)2) as the oxidizer, providing an ignition flame from the primer in a pyrotechnic reaction. The non-toxic primer therefore embodies a lead-free, barium-free, antimony-free explosive material that can include added fuels, sensitizers, explosives and/or binders.
US09409823B2 Microstructured high-temperature hybrid material, its composite material and method of making
This invention provides a hybrid material that exhibits strength, stiffness and ability to resist high temperatures. This hybrid material essentially consists of component A and component B. Component A is selected from the group consisting of inorganic compounds, oxides, carbides, nitrides, borides, and combinations thereof. Component B is selected from the group comprising elemental carbon, inorganic compounds, oxides, carbides, nitrides, borides, and combinations thereof. Component B comprises a plurality of units, each of the units substantially exhibiting a shape, such that this shape substantially exhibits a long dimension and a short dimension, with the short dimension being in a direction that is essentially perpendicular to the direction of the long dimension and the short dimension being in the range from 0.1 nm to 0.5 μm. Each of the units of component B is substantially in contact with and substantially bonded to at least one of the units of component A.
US09409821B2 Compositions and methods for well completions
Particulate polymeric materials may be added to a cement slurry to adjust the linear thermal-expansion coefficient of the set cement. The coefficient of the set cement is optimized by considering the linear thermal-expansion coefficient of the casing, as well as the mechanical properties of the formation rock. When placed in a subterranean well having at least one casing string, cement sheaths with optimal linear thermal-expansion coefficients may be subjected to lower compressive and tensile stresses during downhole-temperature changes. Such cement slurries are particularly advantageous in the context of thermal-recovery wells.
US09409818B2 Sulfo-aluminous clinker with a low belite content
The present invention relates to a new sulfo-aluminate based clinker with a low belite content, a method for preparing this clinker, as well as the use of the clinker for preparing a hydraulic binder, and later on, grout, concrete or mortar.
US09409814B2 Crystalline glass composition and adhesive material using same
Provided is a crystallizable glass composition which exhibits a high coefficient of thermal expansion after undergoing thermal treatment, has excellent fluidity during the thermal treatment, and is less likely to deteriorate the hermeticity and adhesiveness at bonded portions and volatilize glass components even when exposed to high temperatures for a long period after the thermal treatment. A crystallizable glass composition capable of precipitating MgO-based crystals as main crystals by thermal treatment, the crystallizable glass composition containing, in terms of % by mole in glass component composition, 0.1 to 30% La2O3+Nb2O5+Y2O3+Ta2O5+Yb2O3.
US09409811B2 Optical converter system for (W)LEDs
The invention relates to an optical converter system for LEDs, preferably for so-called (W)LEDs, and a method for producing the named optical converter system. The modular-type optical converter system comprises an inorganic converter for converting the radiation emitted from the LED, an inorganic optical component, preferably comprising glass, which is disposed downstream relative to the converter in the direction of emission of the LED, wherein the converter and the first optical component are adjacent to one another and joined at least in sections. The optical converter system possesses a temperature resistance, which lies above that of the system known in the prior art. Also, the preferred components of the system are substantially resistant to UV and to chemicals.
US09409808B2 Glass processing device and bottom machine therefor for manufacturing glass containers
A bottom machine is provided for a glass processing device to manufacture glass containers from glass tubes. The bottom machine includes one or a plurality of holding units for holding the glass container or glass tube, with the holding units being mounted so as to rotate around an axis of rotation of the bottom machine in order to convey the glass container or glass tube to various processing positions, a pressure source for supplying a gas flow, a duct system communicating with the pressure source for directing the gas flow to the holding units and for feeding the gas flow into the glass tube or into the glass container, with the duct system being designed to be free of gaps.
US09409807B2 Use of primary sludge for carbon source in an aerated-anoxic bioreactor system
A method and system of treating wastewater using primary sludge is disclosed. The treatment system includes a primary separator that separates a carbon source comprising non-solubilized suspended carbon from a source of wastewater. The non-solubilized suspended carbon is solubilized and used as a source of carbon in an aerated anoxic treatment system.
US09409806B2 System and method for thermophilic anaerobic digester process
A new approach is proposed that contemplates systems and methods to support an environmentally-friendly, “green” thermophilic anaerobic digestion system. The system includes a thermophilic anaerobic digester as well as various independent modular anaerobic units to generate bio-methane from certain organic energy sources, including but not limited to, among other things, green municipal waste, restaurant and organic waste and effluents from industries such as breweries, grocery stores, food processing plants, granaries, wineries, pulp and paper mills, ethanol and biodiesel plants, fat and animal rendering, agricultural field crops, organic sludge accumulation within lagoons and waterways, marine organic matter and animal manure.
US09409799B2 Gravity flow runoff water purification system
A gravity flow runoff water purification system is provided. The gravity flow runoff water purification system of the present invention includes a debris filter, a grit chamber, and a linear electrolytic reactor. The linear electrolytic reactor includes a plurality of cell chambers separated by at least one fixed electrode plate operable to receive a current. A bi-polar anode blend is disposed at the bottom of each chamber and is charged by the at least one electrode plate using a VLF AC current in order to prevent plating over of fixed electrodes. The blend includes a conductive and consumable metal fraction, a conductive and non-consumable fraction, and a non-conductive pours spacer. Water runs through the debris filter, through the grit chamber and into the linear electrolytic reactor via gravity. The water flows through each of the cell chambers, thereby clarifying and purifying the water.
US09409798B2 Algistatic water treatment solution and method of making
Systems and methods are described that facilitate generating and storing a concentrated copper and silver ion solution for treating a remote water volume (e.g., a pool, fountain, hot tub, cooling tower, etc.), in accordance with various features described herein. Citric acid and a water-soluble binding polymer are added to a volume of water. The intermediate solution is circulated past an ion generator for a predetermined time period, and copper ions generated thereby are bound by the binding polymer and/or chelated by the citric acid. Once a desired concentration of copper ions has been achieved, the concentrated solution is stored in portable vessels for transport to the remote water volume. Concentrated solution is added to the remote water volume to achieve a concentration therein of approximately 0.2-0.3 ppm.
US09409797B2 Device for treating a medium using UV radiation
A device for treating a medium using UV radiation includes a treatment chamber to accommodate the medium. An LED UV radiation source provides UV radiation. A chamber-forming structure has a stiffening base structure with at least one orifice formed therein and has a UV-radiation-transmissive film. The base structure defines a placement of the UV-radiation transmissive film. The chamber-forming structure separates the treatment chamber from the LED UV radiation source, and the UV radiation is introduced into the treatment chamber through the chamber-forming structure.
US09409788B2 Precipitated calcium carbonate from pulp mill waste having an improved brightness, method for the production and use thereof
The present invention relates to a process for the production of a precipitated divalent metal ion carbonate product from a divalent metalion carbonate which was recovered from waste, the precipitated divalent metal ion carbonate product having an improved brightness, the process comprising the steps of: providing a low-purity divalent metal ion carbonate material, the divalent metal ion carbonate material being recovered from waste; calcining the divalent metal ion carbonate material in order to obtain a divalent metal ion oxide; slaking the divalent metal ion oxide in order to obtain an aqueous suspension of a divalent metal ion hydroxide; carbonating the aqueous suspension of the divalent metal ion hydroxide with a carbon dioxide containing compound in order to obtain fine precipitated divalent metal ion carbonate particles; post-treating the fine precipitated divalent metal ion carbonate particles to obtain fine discrete precipitated divalent metal ion carbonate particles; adding the fine discrete precipitated divalent metal ion carbonate particles to an aqueous suspension of divalent metal ion hydroxide that was obtained by slaking high-purity divalent metal ion hydroxide in order to obtain a resulting reaction mixture; and carbonating the resulting reaction mixture in order to obtain the precipitated divalent metal ion carbonate product having an improved brightness.
US09409787B2 Transition-metal-containing zeolite
A transition-metal-containing silicoaluminophosphate zeolite having excellent high-temperature hydrothermal durability is easily and efficiently produced. A method for producing a transition-metal-containing zeolite that contains a silicon atom, a phosphorus atom, and an aluminum atom in at least its framework structure includes hydrothermal synthesis using an aqueous gel containing a silicon atom raw material, an aluminum atom raw material, a phosphorus atom raw material, a transition metal raw material, and a polyamine (other than diamines). A transition-metal-containing silicoaluminophosphate zeolite produced by hydrothermal synthesis using a zeolite raw material and the aqueous gel containing the transition metal raw material and the polyamine has excellent high-temperature hydrothermal durability and high catalytic activity.
US09409781B2 Large-area carbon nanomesh from polymer and method of preparing the same
The present disclosure relates to a polymer-based large-area carbon nanomesh and a method for preparing same. More particularly, the present disclosure provides a method for preparing a carbon nanomesh, including: preparing a polymer nanofilm by coating a solution of a block copolymer or a polymer mixture thereof on a substrate; stabilizing the polymer nanofilm by annealing such that the polymer nanofilm is phase-separated, a pore-forming polymer is removed and, at the same time, a nanomesh-forming polymer forms a stabilized porous polymer nanomesh; and carbonizing the stabilized porous polymer nanomesh by annealing at high temperature to prepare a carbon nanomesh. Using phase separation and cyclization of a polymer, a large-area carbon nanomesh with superior activity can be prepared simply with high reproducibility in large scale.
US09409780B2 Nanostructures patterned by electrostatic printing
An electrostatic printing method such as laser printing can be employed for cost-effective and scalable patterning of nanostructure growth catalysts onto growth substrates, either directly or via one or more transfer substrates. Particles comprising a nanostructure growth catalyst are deposited onto the substrate in an electrostatically defined growth pattern. Another aspect of the method includes pressing a mixture of a nanostructure growth catalyst and a binder against the substrate to bond the mixture to the substrate. Nanostructures are grown from the deposited pattern in known nanostructure growth environments. The method allows a user to define a nanostructure growth pattern using familiar, user-friendly computer programs such as word processors, CAD, or other graphics software. Carbon nanotube forests can be grown from magnetic ink character recognition (MICR) toner printed on or transferred to the substrate.
US09409766B2 MEMS package structure and manufacturing method thereof
A MEMS package structure includes a base, a MEMS device, a first cover, a second cover and a glass frit. The base includes a recess. The MEMS device is disposed in the recess. The first cover is disposed in the recess and covering the MEMS device. The second cover is disposed on the base and covering the recess. The glass frit is disposed between the base and the second cover. A MEMS package structure includes the base, the MEMS device, the first cover, a second cover, a first metal frame and a first sealing medium. The first metal frame is disposed around the second cover, and the second cover and the first metal frame collectively are disposed on the base and covering the recess. The first sealing medium is disposed between the first metal frame and the base. Manufacturing methods of the MEMS package structures above are further provided.
US09409762B1 Liquid delivery nozzle
Provided are nozzles useful for controllably transferring any fluid including without limitation liquids such as hydrocarbon fuels from a first reservoir to a second reservoir. Dispensing nozzles as provided herein have several advantages, including increased control by the technician who is transferring the fluids over the nozzle itself by virtue of greater physical control and less operator fatigue. In addition, a small amount of force applied to the dispensing lever results in a relatively large opening of the control valve mechanism. Further, when line pressure is zero or near zero, it is not possible for un-metered fluid leakage to occur, which provides cost advantages to large volume vendors of liquids such as hydrocarbon fuels which are dispensed on a routine basis, such as at airports. Safety is also greatly enhanced, since latent quantities of fuel cannot flow out from lines equipped with the nozzles provided when supply lines are not pressurized.
US09409761B2 Refillable bottle for dispensing a fluid product
A refillable bottle for dispensing a fluid product including a body in which a reservoir designed for conditioning the product is formed, the bottle including a dispensing device of the conditioned product that is mounted sealed on the body, the bottle being fitted with a reservoir filling valve arranged to enable communication of a product source with the reservoir to refill it, the valve including a communication passage between the source and the reservoir, the passage having a seating fitted with a check valve that is free to move relative to the seating between a sealed closed position and an open position of the passage, the bottle including a device for locking the check valve in the closed position, the device being arranged to be deactivated leaving the check valve in the closed position to release subsequent displacement of the check valve into the open position.
US09409758B2 Faucet-integrated carbonation systems and methods
Systems and methods are disclosed for providing carbonated water through a typical kitchen faucet. The faucet-integrated carbonation system can include a carbonated water reservoir coupled to a residential or commercial cold water supply line as well as a CO2 tank, all of which can be mounted under a kitchen countertop or the like. The water held in the reservoir can be carbonated using the CO2 when a user activates a CO2 activation mechanism. The system can further include a carbonated water on/off valve for dispensing carbonated water from the carbonated water reservoir via a waterway with an outlet disposed at the end of the faucet.
US09409754B2 Piggyback forklift truck and method of operating same
This invention relates to a piggyback forklift truck and a method of operating same. The piggyback forklift truck comprises a motive power unit which includes an electric motor, a rechargeable battery pack powering the electric motor, a battery pack charging unit, a first electricity power supply connector in electrical communication with the battery pack charging unit, a DC/AC converter in electrical communication with the battery pack charging unit, and a second electricity power supply connector in electrical communication with the DC/AC converter, the second electricity power supply being arranged for reception of an electrical power take off feed from a carrying vehicle. In this way, the piggyback forklift truck can be charged by the mains supply when the carrying vehicle is not in transit and can be trickle charged while the carrying vehicle is in transit. This will maximize the operating time of the electrically powered piggyback forklift truck while it is making deliveries to customers.
US09409752B2 Method and apparatus for an emergency lowering kit
A method and apparatus are disclosed for lowering a load on a direct current hoist motor during an electrical power interruption, the method including but not limited to determining in a crane processor that the electrical power interruption has occurred; and providing a brake assist current to shunt field on the direct current hoist motor to produce a counter torque in the hoist motor.
US09409750B2 Removable vehicle top lift system
A removable vehicle top lift system is disclosed herein. Described embodiments of a removable vehicle top lift system include a T-shaped body includes adjustable left, right, and rear arms that may be adjusted to accommodate the size of different removable vehicle tops. The left, right, and rear arms also include hooks for engaging a removable vehicle top. Balancing mechanisms for a removable vehicle top lift system are disclosed. Hooks with mechanisms to hold down a window of a removable vehicle top are also disclosed.
US09409748B2 Elevator safety device and elevator safety device mounting method
A safety supporting body includes: a supporting body main body that is disposed inside a vertical stanchion groove of a car frame; and an engaging portion that protrudes outward from the supporting body main body, and that is hooked onto an upper end portion of a vertical stanchion. The safety supporting body is fixed to the vertical stanchion by a supporting body fixing apparatus. The supporting body fixing apparatus includes: a first fixing bolt that applies pressure between a side surface of the vertical stanchion groove and the supporting body main body; and a second fixing bolt that applies pressure between the engaging portion and a guiding apparatus mounting base that is fixed to the car frame. A safety device main body that applies a braking force to the car by placing a braking member in contact with the guide rail is disposed on the safety supporting body.
US09409742B2 Post-processing device controlling accumulation of sheet onto processing tray according to position of stack tray and image forming system including this post-processing device
A post-processing device includes a device main body, a processing tray, a placed sheet processing part, a stack tray, a detecting part, a stack tray driving part and a sheet conveying part. The processing part carries out post-process to the sheet placed on the processing tray. The stack tray stacks the sheet ejected from a sheet ejection port. The detecting part detects whether or not the stack tray or the sheet on the stack tray is positioned at a detected position below the sheet ejection port. When the sheet is ejected without the post-process, in a detectable case, the conveying part ejects the sheet without placing on the processing tray and, in an undetectable case, the conveying part places the sheet on the processing tray without ejecting to the stack tray until it becomes detectable, and then, ejects the sheet on the processing tray after it becomes detectable.
US09409737B2 Endless clip-strip feed splicer
A splicer machine for feeding strips of closures or clips. The clips formed of flat plastic material, and for receiving portions of flexible bags. More specifically, the automated handling of strips of such clips, where strips of the clips are held together by interlocking portions of the clips.
US09409736B2 Sheet conveying device and image recording apparatus
A sheet conveying device includes a flap pivoting between a first state to contact a first path-defining member and a second state to be separated from a first path-defining member. The first path-defining member, which faces a second path-defining member in a facing direction, includes a guide surface for guiding a sheet conveyed along a first conveying path, a contact surface positioned farther from the second path-defining member in the facing direction than the guide surface and configured to contact the flap in the first state, and an inclined surface positioned downstream of the contact surface in a conveying direction and inclined such that an upstream end thereof in the conveying direction is closer to the second path-defining member in the facing direction than a downstream end thereof. The upstream end of the inclined surface is closer to the second path-defining member in the facing direction than the contact surface.
US09409734B2 Manual paper feeder that ensures stable paper feeding operation and image forming apparatus including the same
A manual paper feeder includes is for installation at a side surface of a main body of an image forming apparatus. When the first auxiliary tray is located at an extension position in a state where the second auxiliary tray is housed downwards, an abutment between an upstream side end edge of the side surface cover and an inferior surface of the second auxiliary tray supports the first auxiliary tray at a first angle. When the second auxiliary tray is extracted from the first auxiliary tray at the extension position, an abutment between the upstream side end edge of the side surface cover and the inferior surface of the first auxiliary tray supports the first auxiliary tray at a second angle. The second angle is smaller than the first angle.
US09409733B2 Conveying apparatus and printing apparatus
A conveying apparatus has first and second trays arranged on an upstream of a conveyor and configured to support the sheet in contact with the conveyor, a feeder configured to feed the sheet on the first tray toward the conveyor, a first sensor configured to output a first signal in response to the sheet being present on the first tray, a second sensor configured to output a second signal in response to the sheet being present between the first tray and the conveyor and configured to output the second signal in response to the sheet being present between the second tray and the conveyor, and a controller configured to execute a removal notifying process to output a notification indicating removal of the sheet on the first tray in response to output of the second signal before a time period since the first signal was output exceeds a threshold period.
US09409728B2 Automated case flow buffer
An automated flow buffer system includes infeed and discharge shuttle systems. A buffering system is disposed between the infeed shuttle system and the discharge shuttle system. The buffering system includes buffer conveyors arranged in an array to buffer one or more items. The infeed shuttle system and the discharge shuttle system each include a shuttle frame disposed proximal to an end of the buffering system and one or more shuttles independently moveable along the shuttle frame. Each of the shuttles include a drive system configured to move the shuttle in horizontal and vertical directions along the shuttle frame so that the shuttle is able to service the conveyors in the buffering system. The shuttle includes a conveyance mechanism upon which one or more of the items are transported. The conveyance mechanism is configured to convey the items to and/or from the buffer conveyors of the buffering system.
US09409720B2 Medium carrying mechanism
Provided is an inexpensive and lightweight carrying mechanism in which side frames and a guide plate are not required to be formed separately and assembled and a small number of components are required. A pair of right and left side frames (2a, 2b) and a medium guide (3) are integrally formed to form a frame structure body (1). On one surface side of the medium guide (3) of the frame structure body (1), a carrying belt (8) for carrying a medium is disposed, and on the other surface side of the medium guide (3), a driven roller (10) for holding the medium between the carrying belt (8) and itself is disposed.
US09409717B2 System for conveying an article using vortex suction units
A system for conveying an article along a transfer path includes at least a first and a second vortex suction unit disposed in sequence in a direction of the transfer path. A conveyor is configured to support the article relative to at least one of the suction units and a main controller is configured to separately control the vortex suction units so as to convey the article along the transfer path using the conveyor.
US09409716B2 Cross belt slat sorter
A conveyor sortation system includes a frame and two or more carriages riding along the frame in a travel direction. Each carriage includes a belt and an electric motor. The belt is oriented at a direction that is transverse to the travel direction of the carriage. The electric motor is configured to drive the belt. In one form, the belt has a width that is at most 8 inches (20.32 cm) wide. In another form, the carriages have a vertical recirculation pattern along the frame.
US09409707B2 Secondary containment unit and methods
A modular secondary containment unit that can be adapted to surround an above-ground fluid storage tank and can include a plurality of corner assemblies is described herein. Two or more components of each of the corner assemblies can be composed of one or more reinforced resin composite materials. The modular secondary containment units and the above-ground fluid storage tanks can be used in oil and gas exploration and production operations. An assembly for a modular secondary containment unit can include a track segment including first and second channels, a wall segment mounted on the track segment and extending within the first channel of the track segment, and a brace engaged with the wall segment and extending within the second channel of the track segment. A method of constructing a modular secondary containment unit is also provided.
US09409706B2 Container having padded dunnage supports and L-shaped tracks
A container (10a) comprising a metal frame (164) for holding product therein during shipment and being returned for reuse has a base (166) and opposed sides, L-shaped tracks (60), and a plurality of padded dunnage supports (94) extending between the tracks (60). One type of padded dunnage support (94) comprises end members (98) and a tubular middle member (102), the end members (98) being movable along the tracks (60). The padded dunnage supports (94) support dunnage (136), such as pouches (138).
US09409705B2 System, a method and a capsule for preparing a pre-determined quantity of beverage
A system and method for preparing a predetermined quantity of beverage suitable for consumption using an extractable product includes at least one disposable capsule; an apparatus comprising a fluid dispensing device for supplying an amount of fluid to the at least one capsule, a receptacle for accommodating the at least one capsule, and an outlet arrangement for supplying the beverage to a container, such as a cup. The at least one disposable capsule comprises a material barrier for enclosing an inner space comprising the extractable product. The disposable capsule further comprises a displaceable body conceived to interact with the material barrier for discontinuing at least an exit area thereof for enabling passage of the at least a portion of the beverage away from the capsule.
US09409703B2 Portion capsule for producing a beverage using a portion capsule
A portion capsule for producing a beverage has a capsule body with a capsule base and a filling side. A cavity for accommodating a pulverulent or liquid beverage base is formed between the capsule base and the filling side, and a filter element is arranged between the beverage base and the capsule base The filter element includes an open-pore felt and/or nonwoven. The felt and/or the nonwoven have/has an average first pore size in a first region which faces the beverage base and an average second pore size in a second region which faces the capsule base, wherein the first pore size is smaller than the second pore size.
US09409700B1 Nozzle protector assembly
A decor-able, multiple-configuration protector for the nozzle assembly of a spray can having parts capable of absorbing, deflecting, and/or redirecting damaging force from accidental drops and bumps.
US09409696B2 Multi-chamber container
Provided is a multi-chamber container for dispensing flowable substances, comprising: a body having: a first storage chamber for storing a first flowable substance, a second storage chamber for storing a second flowable substance, a mixing chamber, a first inlet that fluidly connects the first storage chamber with a first portion of the mixing chamber, and a second inlet that fluidly connects the second storage chamber with a second portion of the mixing chamber; and a closure having a divider, wherein the closure is movable relative to the body between: (a) a first position, at which the divider isolates the first portion of the mixing chamber from the second portion of the mixing chamber and the closure is spaced from the first and second inlets, and (b) a second position, at which the first portion of the mixing chamber is in fluid communication with the second portion of the mixing chamber.
US09409694B2 Multi-chamber container
Provided is a multi-chamber container for dispensing flowable substances, comprising a body and a closure movable relative to the body. The body comprises respective storage chambers for storing respective flowable substances, and a vessel defining respective outlet zones having respective outlets and a separator between the outlet zones, and movable relative to the storage chambers between a first position and a second position. The body also comprises respective inlets that fluidly connect the respective storage chambers with the respective outlet zones, and first and second members that are each movable between (a) an inactive state, at which the respective member seals a respective inlet to isolate a respective storage chamber from a respective outlet zone and a respective outlet is open so that the respective outlet zone is in fluid communication with a downstream side of the respective outlet, and (b) an active state, at which the respective member seals the respective outlet to isolate the respective outlet zone from the downstream side of the respective outlet, and the respective inlet is open so that the respective storage chamber is in fluid communication with the respective outlet zone. Movement of the vessel between the first position and the second position causes the first and second members to move between their respective inactive and active states.
US09409692B2 Flexible shipment packaging
A shipment packaging for elongate components is provided. Turbine blades must be sent from remote locations of the world to another location. During shipment, the coating of the turbine blades must be protected. The turbine blades are fixed at both ends by means of shipment packaging so that the turbine blades are protected.
US09409689B2 Easy opening display package for merchandise
A display package for an item of merchandise, e.g., a toothbrush. The package is formed of a first wall member, e.g., a blister body, having a recess and a peripheral flange. A second elongated wall member, e.g., a planar sheet of film having an inner surface and an outer surface, is fixedly secured by its inner surface to the peripheral flange of the first wall member to enclose the item of merchandise therebetween. The second wall member includes an access window formed by a pair of elongated frangible lines and an access slit. Each of the frangible lines is cut only partially through the thickness of the second wall member, starting from the inner surface of the second wall member. The access slit is located at one end of each of the frangible lines. The window is arranged to be opened by a user grasping portions of the second wall member at the access slit to break the frangible lines and thereby provide access to the item of merchandise.
US09409687B2 Stand up package
A stand-up package is formed to include an interior region for containing a product. The package is configured to be in an upright, standing position. The stand-up package includes a film-rigidifying frame and a film pouch. The film-rigidifying frame is coupled to the film pouch so that the film pouch assumes an upright position.
US09409682B2 Non-removable container neck ring
A product includes a container including a neck, and a ring non-removably secured to the neck of the container. The ring may be used to non-removably couple a fitment to the container and/or may be adapted irreversibly to change a characteristic of the ring that is visible from outside of the container to advise a user that the package has been opened.
US09409680B2 Tamper evident closure
A tamper-evident dispensing closure includes a body adapted to be attached to a container. The container has a shoulder portion surrounding a dispensing opening. The closure body has a peripheral wall and a top wall which extends over one end of the peripheral wall, such that the corresponding end of the body is closed off by the top wall and an opposite end of the body is open. The open end is in use placed over the shoulder portion of the container. The top wall is provided with a dispensing passage which in use is in line with the dispensing opening of the container. The peripheral wall is provided with tamper-evident means, which cause the peripheral wall to rupture when the closure is removed from the container, thereby indicating tampering.
US09409678B2 Magnetic bottle and substrate dispensing assembly
A bottle body structure includes a substrate accommodating a container bottle which includes an inner bottle body, an outer container bottle and a bottle cap. The bottle cap can be accommodated inside the outer bottle body and the side wall of the bottle cap is provided with a discharge hole. An ejecting mechanism, enabling the inner bottle body to displace axially relative to the outer bottle body to expose the discharge hole out of the outer bottle body, is provided between the inner bottle body and the substrate. As a result, the bottle body structure conceals the discharge hole in the outer bottle body and the ejecting mechanism enables the inner bottle body to eject automatically to expose the discharge hole, which is convenient to use and hygienic. Material in the bottle can be poured out easily with one hand. The bottle body is especially applicable to storage of spices.
US09409673B2 Pallet with single layer top deck having inserts therein and related methods
A pallet includes a cargo layer, a base layer and support structures coupled between. The cargo layer includes a pair of horizontally positioned outer deck boards and at least one horizontally positioned intermediate deck board therebetween. The at least one horizontally positioned intermediate deck board has opposing sidewalls, and a spaced apart openings at least partially extending through the opposing sidewalls. The pair of horizontally positioned outer deck boards have opposing sidewalls, and spaced apart openings extending through at least one of the sidewalls of each outer deck board. The spaced apart openings in each horizontally positioned outer deck board are aligned with the spaced apart openings in an adjacent sidewall of least one horizontally positioned intermediate deck board. Inserts are in the spaced apart openings.
US09409666B1 Apparatus for collecting debris and method of use
Apparatus for collecting debris which resides upon a support surface includes a body which has an open mouth end and an opposite closed end. Two diverters are connected to opposite sides of the open end. The diverters are angularly positioned so that they channel the debris into the open end of the apparatus. In one embodiment the apparatus is held in place by staking the distal ends of the diverters to the support surface such as a lawn. In another embodiment weights are placed in pockets in the diverters to hold the apparatus in place on a hard surface such as a driveway.
US09409662B2 Formulations of albu-BChE, preparation and uses thereof
The present invention provides an aqueous pharmaceutical composition comprising the fusion protein whose amino acid sequence is set forth as SEQ ID No:1 and an aqueous solution comprising 40 to 60 mM sodium phosphate. The present invention further provides a lyophilized pharmaceutical composition, an reconstituted solution, a sealed package comprising the lyophilized pharmaceutical composition, and a vial comprising the lyophilized pharmaceutical or the reconstituted solution. The present invention also provides a method of producing the lyophilized pharmaceutical composition and the sealed package. The present invention also provides a method of treating a human having cocaine seeking behavior, and methods of using the aqueous pharmaceutical composition and lyophilized pharmaceutical composition.
US09409658B1 Space-based structures and methods of delivering space-sourced materials
A method is provided for processing extraterrestrial metal into a metal foam or gossamer structure in space, and delivering the metal foam or gossamer structure intact to the Earth's surface. Additionally, a structure is provided that is formed in space and consists essentially of an extraterrestrial metal.
US09409654B2 System and method for improved low airspeed warning
A method and system are provided for generating a low airspeed warning in an aircraft. This method creates a scale factor that is a factor of engine thrust and aircraft altitude. A low airspeed threshold is determined that varies according to the aircraft altitude with respect to a predetermined altitude band and the engine thrust with respect to a predetermined engine thrust band. A low airspeed alert is generated in response to the determination of the low airspeed threshold. This method provides a pilot with earlier knowledge of low airspeed conditions when the aircraft is in a target altitude band, increasing the pilot's response time and thereby enhancing overall aircraft safety.
US09409651B2 Aircraft aerial refuelling system
An aircraft aerial refueling system including at least one pressure controlled fuel pump having a control system adapted to regulate the pump outlet fuel pressure using an outlet fuel pressure signal as control feedback. Also, methods of operating an aircraft aerial refueling system.
US09409644B2 Automotive drone deployment system
This disclosure generally relates to an automotive drone deployment system that includes at least a vehicle and a deployable drone that is configured to attach and detach from the vehicle. More specifically, the disclosure describes the vehicle and drone remaining in communication with each other to exchange information while the vehicle is being operated in an autonomous driving mode so that the vehicle's performance under the autonomous driving mode is enhanced.
US09409639B1 Method and system for protection of vessels against intrusions
A method and system for creating a water wall around the perimeter of a ship by pumping a high-pressure water stream through a plurality of rotational water dispensing heads positioned around the perimeter of the ship. Each of the water dispensing heads produces a water circle and the overlapping water circles create a water wall around the ship that cannot be broken by the intruders attempting to approach the ship and to climb on board. Each water heads has several jets dispensing water streams under high pressure. The water heads rotate under an impact of the water streams coming at an angle from the water dispensing jets. Thus, the entire boat is covered by a continuous water wall barrier, which does not allow for any intrusion attempts from another boat or from a pier.
US09409637B1 Enhanced system and method for remotely deploying boat fenders
An enhanced system and various methods for remotely deploying boat fenders from a safe and convenient location. The fenders, which are placed along the entire periphery of the boat, may be deployed and retracted with lines attached to winches and motors. A smart phone app may be employed to remind users to deploy fenders upon entering known ports, and may also deploy the fenders automatically.
US09409632B2 Cabin for a floating installation with lines which contribute to reinforcement
The invention relates to a cabin (70) for a floating installation, in particular for a ship (60), having a room unit (1) which is bounded at least by a ceiling (10) and walls (20), and lines (30) which supply the room unit (1), in particular with air, water, data, power, illumination, etc. Provision is made according to the invention for the lines (30) to extend in the room unit (1) in such a way that the lines (30) simultaneously act as reinforcing means for the room unit (1).
US09409631B2 Loading hose
A hydrocarbon loading hose (4) for connection between a GBS (1) and a shuttle hydrocarbon transport vessel (2), arranged in water (W) and at a distance apart, comprises buoyancy means (5) in its mid region and at least one buoyancy element (7a, b) in a free end region.
US09409628B2 Suspended boat cover
A boat cover for a suspended cover system that is configured to fit a boat in a manner that prevents relative movement therebetween minimizing wear. The cover has at least one fitting seam that follows part of the top of the boat. An integral cover cinching arrangement enables tightening the bottom of the cover against the hull bugging it. Vents overlying a passenger section minimize wind force by reducing cover pressure differential. The cover can be equipped with a second fitting seam that extends along the gunwale of the boat and can have a downwardly extending fitting seam section that extends below the gunwale toward the bow to help fit the cover to the front portion of the hull of the boat. Stretchable straps used to hang the cover from a track of the boat cover system can be used to minimize force on the cover caused by wave action.
US09409627B2 Collapsible watercraft assembly
A collapsible watercraft assembly can include a first pontoon half, a second pontoon half, and a frame member. Each pontoon half can have a top surface, a bottom surface, and at least one post. The first pontoon half and the second pontoon half can be positionable with respect to one another in an operating configuration and a stowed configuration. The operating configuration can be defined when the sterns of the pontoon halves confront one another and the stowed configuration can be defined when the top surfaces of the pontoon halves confront one another. The frame member can be concurrently engageable with the posts to fix the pontoon halves together in the operating configuration. The posts can be interconnected with one another when the first pontoon half and the second pontoon half are in the stowed configuration.
US09409626B2 Floating unit
A floating unit comprising: a hull having a recess in which a deployable wall is mounted, the wall being movable between a first and a second position; wherein in the first position the wall is enclosed within the hull in the recess; and in the second position the wall at least partly protrudes from the hull, thereby defining a partly enclosed space; and wherein the floating unit further comprises means for supplying air bubbles to the partly enclosed space, the partly enclosed space being configured to constitute an underwater air pocket filled with air bubbles upon supplying the air bubbles from the means for supplying the air bubbles when the floating unit floats in the water with the wall in the second position.
US09409624B2 Bicycle sprocket
A bicycle sprocket comprises sprocket teeth. The sprocket teeth include a first tooth and a second tooth. The first tooth has a chain-engaging axial width which is larger than a first distance defined between opposed inner link plates of a bicycle chain and which is smaller than a second distance defined between opposed outer link plates of the bicycle chain. The second tooth has a chain-engaging axial width which is larger than the first distance and which is smaller than the second distance. The first tooth and the second tooth are spaced apart from each other in a circumferential direction of the bicycle sprocket to define a space which is free of a tooth configured to engage with the bicycle chain.
US09409618B2 Guide device for a flexible linking member passing into a bicycle frame
The device is designed to guide a flexible linking member passing into a bicycle frame to link a control member carried by bicycle handlebars to a receiver. The linking member (14) enters the bicycle frame via an inlet opening (15) formed in a head tube (1). The guide device (3) forms an insert that can be built into the head tube (1) and includes a guide channel (17) for the linking member (14) intended to communicate with the inlet opening (15). The insert (3) can be placed inside the head tube (1) in a seat (4) shared with an upper bearing (2) of a headset and has an internal face that can at least partially surround a fork steerer (6) inserted in the head tube (1), and an external face containing the guide channel (17).
US09409615B2 Motorcycle
A motorcycle includes a detachable pannier. A rear surface of the pannier includes a first inclined surface extending downward from an upper end so as to be inclined rearward, and a second inclined surface extending downward from a lower end of the first inclined surface so as to be inclined rearward at an angle greater than the first inclined surface. A light distribution requirement that a tail lamp and a turn indicator can be seen from a rear side is met in a state where the pannier is mounted.
US09409614B2 Bicycle saddle structure
A bicycle saddle structure includes a saddle portion having two elastic supporting bodies in a bottom surface thereof and a nose position pivoted to the saddle portion, the elastic supporting bodies are circular spiral-shaped, which can provide a buffer force to the rider, so as to improve the riding comfort. The nose portion can be selectively located at the same level as or vertical to the saddle portion via a pivoting unit, the saddle can be changed to the nose-shaped saddle or the saddle without nose portion, so as to improve the applicability.
US09409605B2 Vehicle body side part structure
A structure is configured such that a viewer hardly feels strangeness of color tone or texture even when paint mist is attached to a center pillar 3 during coating of a body outer plate. A panel surface of an outer panel 35 of the center pillar 3 has a protrusion in a middle in the vehicle vertical direction such that at least part of a lower portion of the panel surface projects toward the outside of the vehicle body relative to an upper portion of the panel surface. A start end HL of the protrusion is located at substantially an identical height to a door body upper edge line UL in at least a center portion in a pillar width of the pillar outer panel.
US09409598B2 Replaceable coupling cartridge
A universal replaceable cartridge for coupling together members of a linkage assembly. The cartridge includes a generally cylindrical body having first and second ends and first and second surfaces. A first threaded portion is formed on the first surface of the cylindrical body adjacent the first end and a second threaded portion is formed on the second surface of the cylindrical body adjacent the second end. The threaded portions allow the cartridge to be threadedly attached to first and second members of the linkage assembly.
US09409597B2 System and method to select a steer mode
The present disclosure is related to a system to control switching between a two wheel steer mode and a four wheel steer mode. The system may have a sensor device that monitors an operational value indicative of vehicle speed and emits an operational signal corresponding to the operational value. A controller is provided in the system, which receives the operational signal and selects between the two wheel steer mode and the four wheel steer mode based on the operational signal.
US09409591B2 Steering device
A steering device which slides when an impulse load is applied. A steering device includes an inner column having a cylindrical shape, an outer column into which at least a part of the inner column is inserted, a column bracket tightening the outer column, a pressed portion provided on the outer periphery of the inner column, a first tightening mechanism tightening the outer column in response to a rotation of a manipulation lever, a second tightening mechanism biasing a lock member to the pressed portion in a tilt direction in response to the rotation of the manipulation lever, and a separation mechanism. The separation mechanism causes the inner column detachable by changing a relative position between the inner column and the pressing bracket, when the impulse load is applied in a state where the first tightening mechanism and the second tightening mechanism are in work.
US09409590B2 Steering device
A steering device which slides when an impulse load is applied. The steering device includes an inner column having a cylindrical shape and a first hole opened therein, an outer column having a slit, an outer column bracket to tighten the outer column, an inner column bracket having a second hole opened therein, and a connection member provided at a position straddling the first hole and the second hole and detachably connecting the inner column and the inner column bracket. The telescopic friction plates are disposed at both sides of the outer column. The inner column bracket includes an arm portion connecting the telescopic friction plates disposed at both sides of the outer column, a neck portion projected from the arm portion, and a leg portion provided at an end opposite to the arm portion of the neck portion and contacting the inner column.
US09409589B2 Front-mounted stand-on lawn care vehicle
A riding lawn care vehicle may include: (a) a frame to which a pair of front wheels and a rear wheel assembly of the riding lawn care vehicle are attachable; (b) an engine mounted to the frame substantially between the front wheels; (c) a steering assembly having steering levers operably coupled to respective ones of the front wheels of the riding lawn care vehicle via respective hydrostatic drive pumps driven by the engine; (d) a support platform coupled to the frame rearward of the engine to support a standing rider; and (e) a front mount assembly configured to detachably couple the riding lawn care vehicle to an attachment that enables performance of a yard maintenance activity, where (f) a majority of the support platform is disposed rearward of an axis of rotation of the front wheels and forward of an axis of rotation of the rear wheel assembly.
US09409587B1 3 in 1 ladder, dolly, and seating systems
The 3 in 1 ladder, dolly, and seating system is a portable, device that can function as a set of stairs, a ladder, a seating area, and a cargo dolly. It is a four wheeled dolly, or a two-handle hand truck with two wheels in front, and can extend to become a ladder or various types of stairs, including steps for sitting. It is constructed from durable aluminum, or another appropriate material. The device can convert into a set of stairs with removable guardrails, or a smaller set of stairs that can be used as seating with foldable backrests. It can be manufactured with an umbrella holder and an optional canopy tent.
US09409581B2 Knuckle design and system of making
Railcar coupling knuckles having areas of improved structure, improved surface characteristics, and reduced stress under loading, and systems and methods for shot peening railcar components such as, but not limited to, coupling knuckles. Such shot-peening systems and methods may include robotic and/or fixed-position shot-peening devices equipped with shot-emitting mechanisms for expelling shot media against desired areas of a railcar component.
US09409580B2 Obstacle removing and energy absorbing device and leading car of motor train unit
An obstacle removing and energy absorbing device provided with an obstacle removing beam (6) and a bumper cross-beam (15) which are oppositely arranged, an energy-absorbing tube assembly with an energy-absorbing tube (9) is fixedly connected between the obstacle removing beam (6) and the bumper cross-beam (15), a mounting base (8) is fixedly connected with one end of the energy-absorbing tube (9), a crushing support (13) is threaded onto the other end of the energy-absorbing tube (9), the crushing support (13) is provided with a variable-diameter through-hole, a crushing-convex portion (20) is provided in the variable-diameter through-hole, a concave portion (21) matched with the crushing-convex portion (20) is arranged at an end portion where the energy-absorbing tube (9) is penetrated into the crushing support (13), the mounting base (8) is fixedly connected with the obstacle removing beam (6), the crushing support (13) is fixedly connected with the bumper cross-beam (15).
US09409579B2 Method for monitoring a door contact switch of a driver's door of a motor vehicle
A method for monitoring a door contact switch of a driver's door of a motor vehicle locked in an idle state includes detecting an unlocking of the driver's door of the motor vehicle, and detecting whether a change in a door contact signal of the door contact switch takes place after the unlocking of the driver's door. If a change in the door contact signal has been detected, a plausibility counter is initialized, otherwise the method includes detecting whether a drive unit of the motor vehicle is activated. A “door contact implausible” state is established and the plausibility counter (P) is incremented if the activation of the drive unit has been detected in step d).
US09409577B2 Method and apparatus for controlling torque intervention of hybrid electric vehicle
A method and an apparatus for controlling torque intervention of a hybrid electric vehicle are provided that determine a final engine torque and a final motor torque considering efficiency of a hybrid system. The method includes calculating a demand torque of a driver, determining receipt of a signal of the torque intervention, and calculating the demand torque of the driver on which an intervention torque is reflected. In addition, the method includes calculating first operating points of the engine and the motor considering an efficiency of the hybrid system according to the demand torque of the driver on which the intervention torque is reflected, calculating a final engine torque and a final motor torque according to each of the first operating points of the engine and the motor, and adjusting a torque reduction using the final engine torque and the final motor torque.
US09409573B2 Vehicle speed determination system, stability control system, and saddled vehicle having the same
A vehicle speed while curving through steering maneuver is determined. A vehicle speed determination system is applicable to a vehicle having a front wheel and a rear wheel. The system includes: a wheel speed sensor configured to detect a wheel speed Vf of the front wheel; and an arithmetic circuit configured to determine a vehicle speed V(r) at a rear-wheel tangential point, based on a difference in vehicle speed between the front-wheel tangential point and the rear-wheel tangential point which occurs due to a difference between a locus of travel of the front wheel and a locus of travel of the rear wheel, and on the wheel speed Vf of the front wheel.
US09409572B2 Drive assist system, drive assist method, and drive assist device
A drive assist system includes: a movable body (20) in which drive assist is performed by an assist device (40, 50, 60) and which includes a movable body holding unit (23); an external holding unit (14) located outside the movable body (20); and a controller (22) configured to determine whether or not an operation position where the assist device (40, 50, 60) operates is related to the operation of the assist device (40, 50, 60), select the external holding unit (14) as a unit in which the operation result of the assist device (40, 50, 60) is to be held when it is determined that the operation position is not related to the operation of the assist device (40, 50, 60), and select the movable body holding unit (23) as the unit in which the operation result of the assist device (40, 50, 60) is to be held when it is determined that the operation position is related to the operation of the assist device (40, 50, 60).
US09409568B2 Hybrid vehicle drive apparatus
A hybrid vehicle drive apparatus includes an engine, a transmission unit, and a differential unit. A dual-motor travel is possible by stopping the engine and driving a first rotating machine and a second rotating machine as a result of engaging a first engaging element and a second engaging element of the transmission unit. At a time of switching to a dual-motor travel, the hybrid vehicle drive apparatus executes a first control for carrying out a negative RPM control by the first rotating machine; a second control for engaging either one of a first engaging element and a second engaging element of the transmission unit; and a third control for engaging both of the first engaging element and the second engaging element of the transmission unit after the first control and the second control.
US09409567B2 Driving assistance apparatus
A driving assistance apparatus includes an assistance control unit determining an on/off state of an engine and a drive control unit controlling driving of the engine on the basis of the on/off state determined by the assistance control unit. The assistance control unit determines whether a vehicle stops at a target stopping position, and carries out setting such that the engine is more easily switched from the on state to the off state when the assistance control unit determines to stop at the target stopping position and it is timing at which the vehicle is able to reach the target stopping position in a state where driving force is not generated.
US09409566B2 Hybrid vehicle and associated control method
A hybrid vehicle and method of control are disclosed wherein the ratio of engine speed to vehicle speed varies continuously in some operating modes and is controlled to simulate a discrete ratio transmission in other operating modes. The disclosure specifies the method of controlling the engine speed and the combined output torque of the engine and at least one traction motor in each of the operating modes. Transitions among operating modes occur in response to driver movement of a shift lever, driver operation of shift selectors, and changes in vehicle speed.
US09409565B2 Hybrid electric vehicle control system and method
The present invention relates to a control system for a hybrid electric vehicle having an engine (121) and first (123C) and second (123B) electric machines operable as propulsion motors. The second electric machine is arranged to be drivably coupled to the engine, the engine being arranged to be drivably coupled to a driveline of the vehicle by clutch means (122). The system is operable to control the vehicle to operate in one selected from amongst: an engine-driven mode in which the clutch means is closed and the engine applies torque to the driveline of the vehicle; an electric vehicle (EV) mode in which the clutch means is open and the first electric machine applies torque to the driveline; and an EV boost mode in which the clutch means is closed and both the first and second electric machines apply torque to the driveline, the engine being motored by the second electric machine, the mode in which the vehicle is operated being selected by the system in dependence on the value of one or more vehicle parameters.
US09409558B2 Hydraulic brake system and method as well as control device for its operation
A hydraulic brake system has: a force-pressure conversion element, which is in hydraulic connection with at least one wheel brake cylinder of at least one wheel; a volume-adaptation element in hydraulic connection with the at least one wheel brake and the force-pressure conversion element; and as an actuating unit for actuating the force-pressure conversion element, which actuating unit has an input element. The pressure in the at least one wheel brake cylinder is adjusted by operating the volume-adaptation unit and/or the actuating unit. For this purpose an actuating state of the input element is maintained by operating the actuating unit when the volume-adaptation unit is being operated.
US09409549B2 Autonomous vehicle window clearing
At least one datum is received relating to a condition of a window in the vehicle. A determination is made to change a parameter based on the at least one datum, the parameter governing clearing the window. An instruction is provided to initiate or change operation of a vehicle component based on the change of the parameter.
US09409546B2 Seatbelt-retracting device
A device for retracting a seatbelt, having a shaft and main drive spring which prestresses the shaft in a retracting direction of the seatbelt, and a locking wheel rotatably arranged relative to the shaft, and a blocking device with a locking lever for blocking a rotational movement of the locking wheel in the retracting direction, and a compensating spring arranged such that when the locking wheel is blocked, said compensating spring transmits to the shaft a prestressing force counteracting the prestressing force of the main drive spring. The blocking device has a switching lever for activating the locking lever, the switching lever being arranged pivotably about an axis which is parallel to the axis of the shaft, and has a first engagement element and a second engagement element which is guided on a positive cam of a control disk which is connected in a rotationally fixed fashion to the shaft.
US09409545B2 Belt retractor with a child lock
A belt retractor (10) for a vehicle seat belt includes a frame (12) provided with plural blocking teeth (22), a belt reel (14) which is rotatably supported in the frame (12) and includes a blocking tooth system (24), and a control mechanism by which the belt reel (14) can be moved from a home position in which it can freely rotate in the frame (12) into a blocking position in which its blocking tooth system (24) engages in the blocking teeth (22) of the frame. The control mechanism includes a locking lever (80) adjustable between a release position and a locked position in which it locks rotation of the belt reel (14) relative to the control mechanism so that the belt reel (14) can be moved into the blocking position by a tensile force acting in the webbing.
US09409541B2 Interior trim part for a motor vehicle comprising an airbag door
Interior trim part for a motor vehicle comprising a body, a channel-door assembly, a sealing system and a foam layer. The body comprises a passage. The channel-door assembly is mounted on the body. The channel-door assembly comprises a channel wall and a door portion. The channel wall has an inner surface and an outer surface, the inner surface being intended to guide the deployment of an airbag, the outer surface extending along a deployment direction. The door portion is connected to the channel wall and overlies the passage. The sealing system extends around the outer surface of the channel wall, in continuous contact with the body and comprises a lip protruding from the outer surface of the channel wall. The foam layer covers the body and the door portion.
US09409539B2 Vehicle seat airbag system and vehicle seat
A vehicle seat airbag system includes an airbag which is caused by the vehicle seat airbag system to inflate and develop within a seat back. A plurality of elastic installation supporting members is provided within a seat back frame that forms the framework of the seat back of a seat for the vehicle. A seat pad is disposed on the front surface of each elastic installation supporting member. The airbag in a contracted state is disposed rearwardly of the elastic installation supporting members. All of these components are covered by an outer layer material in a bag shape. The airbag, which inflates and develops in the seat back due to a collision or the like, elastically supports the upper body of a seated person, and elastically receives an impact force which is applied to the rear of the seat back.
US09409532B2 Edge seal with sidewall seal
A resilient seal for mobile living quarters around a slide out room that includes a pair of mounting portions extending along the inside and outside surfaces of the main living area wall at an aperture through which the slide out room moves and further includes a connecting member extending between the attaching members and along the edge of the wall defining the aperture. The seal includes a flexible protrusion that can conform to an irregular surface or for accommodating walls of different thicknesses. A wiper seal extends from the connecting member to flex against the walls of the slide out room.
US09409530B2 Device for protecting the inside of vehicles
The invention relates to a device for protecting the inside of vehicles. Said device comprises: at least one U-shaped arch (1), the shape of which is complementary to the inner shape of the walls (11), roof (12) and/or floor (14) of the inner compartment (13) of a motor vehicle (10), provided with elements (2) for securing to the body, that detachably and dismountably secure the arch (1) to the inside of the inner compartment; and a IV laminar protection cover (3) provided with connecting means (5) that connect to the arches (1) by means of the cooperation of said strips (5) with at least one arch-fixing element (4). The invention provides a device that is easy to install and protects the inside of vehicles that carry loads or aggressive elements that dirty and/or damage the loading area of the inside of the body and/or the upholstery thereof.
US09409528B1 Lightbar mounting system
A universal system for mounting lightbars on any vehicle's roof curvature without the need for changing parts in the mounting. The mounting system comprises two mounting assemblies. Each assembly has a first bracket attached to the roof, particularly in the gutter or door jamb, which runs along the edge of the roof, a second bracket attached to the underside of the lightbar, and a third bracket coupled to said first bracket by a flexible strip or strap. The third bracket is movable laterally with respect to the second bracket to a fixed position to stretch the strip so that it lies flush upon the roof. Two of the mounting assemblies are attached to the lightbar at opposite ends thereof for mounting the lightbar along the right and left sides of the roof of a vehicle.
US09409524B2 Narrow sliding storage bin
A sliding storage compartment assembly for a motor vehicle includes a storage bin including parallel side rails defined on opposed sides thereof and a pair of outboard guides each defining a channel for slidably receiving a bin side rail therein. A housing slidably receives the bin. The housing includes parallel slots defined in opposed sidewalls thereof, with each slot being configured to receive a parallel channel defined in an outboard guide. Each sidewall of the housing includes a plurality of locator pins. Each outboard guide includes at least one cooperating two-way locator slot and at least one cooperating four-way locator aperture for aligning the outboard guide and the housing sidewall.
US09409521B2 Protection device for a storage space of a motor vehicle and drive device therefor
Protection device for a storage space of a motor vehicle. Such a protection device having a cartridge housing, in which at least one flexible planar formation is supported so as to be able to be wound and unwound, wherein the cartridge housing is able to be positioned so as to be secured to the storage space in vehicle-side retention receiving members, wherein the retention receiving members can be displaced inside the storage space by means of a kinematic displacement system, is known. The kinematic displacement system has vehicle-side linear guides, which extend with a main direction component in the vertical direction of the vehicle and in which the retention receiving members are guided, and there is provided a storage-space-base-side recess in which the cartridge housing is arranged in a recessed manner in a rest position. Use in private motor vehicles.
US09409518B2 System and method for enabling a driver of a vehicle to visibly observe objects located in a blind spot
A system for enabling a driver of a vehicle to visibly observe objects located in a blind spot includes, but is not limited to, a rear view viewing device that is mounted to the vehicle and configured to be electronically adjustable. The system further includes a sensor that is associated with the vehicle and that is configured to detect a location of an object with respect to the vehicle and to generate a first signal indicative of the location of the object. The system further includes a processor that is communicatively coupled with the sensor and that is operatively coupled with the rear view viewing device. The processor is configured to obtain the first signal from the sensor and to command the rear view viewing device to adjust such that the object is visibly observable to the driver when the processor receives the first signal.
US09409516B2 Vehicle approach notification sound generating apparatus
An object of the present invention is to provide a vehicle approach notification sound generating apparatus that communicates with another vehicle so as to be capable of generating a vehicle approach notification sound different from another vehicle. The vehicle approach notification sound generating apparatus of the present invention includes a vehicle approach notification sound acquiring unit that acquires the vehicle approach notification sound output from another vehicle, a similarity distance calculating unit that calculates a similarity distance between the vehicle approach notification sound of the own vehicle output from a vehicle approach notifying unit and the vehicle approach notification sound of another vehicle acquired by the vehicle approach notification sound acquiring unit, a communication unit that is communicable with another vehicle, and a controller that communicates with another vehicle via the communication unit, makes adjustment whether the vehicle approach notification sound of another vehicle or the own vehicle is to be changed, and when the vehicle approach notification sound of the own vehicle is to be changed, makes control to change the vehicle approach notification sound of the own vehicle so that the similarity distance calculated by the similarity distance calculating unit is a predetermined threshold or more.
US09409513B2 Braking intensity indicator system including selective adjustment of brake pedal light and related methods
A braking intensity indicator system for a vehicle of a type that includes a foot operated brake pedal and at least one brake light may include a proximity sensor to be associated with the brake pedal and a controller. The controller may be configured to cooperate with the proximity sensor to determine a plurality of brake pedal positions versus time during foot operation of the brake pedal, and selectively adjust an intensity of the at least one brake light based upon the determined plurality of brake pedal positions versus time.
US09409509B2 Device for securing stored materials in a storage space and securing element therefor
A device having a securing element which can be blocked in a load rail which is anchored so as to be fixed to a vehicle, the securing element having a base member with a retention region which can be inserted into the load rail in a positive-locking manner, and the base member includes at least one bar member for engagement in a catch bar arrangement of the load rail which is supported so as to be able to be moved relative to the base member. A additional bar is provided which is movably supported parallel with the bar member and independently of the bar member, and which is resiliently loaded in the direction of the blocking position and which can be moved together with the bar member into the release position.
US09409506B2 Conveyance seat
A conveyance seat includes: a seat frame; a seat pad that covers the seat frame; and a seat cover that covers the seat pad and that is fixed to the seat frame. The seat pad has a U-shaped portion formed by a supporting portion, a side surface portion that is continuous with the supporting portion, and a tension adjusting portion that is continuous with the side surface portion, the tension adjusting portion having a protruding portion as a portion of the tension adjusting portion that protrudes toward the seat cover. The protruding portion abuts against the seat cover.
US09409504B2 Flexible seatback system
A vehicle seat suspension system includes first and second side supports defining a seatback structure. An upper component and a lower component are provided, each including at least two outwardly extending flex members. A passenger support includes a periphery operably coupled to distal ends of the flex members. An external peripheral gap is defined between the passenger support and the seatback structure.
US09409500B2 Upper body support system
An upper body support system helps stabilize and restrict undesirable movement by an upper body. The system either detachably connects to the mounting surface, or forms an integral unit with the mounting surface. In either case, a stretchable extension between the mounting surface and the upper body is formed with a flexible strap. The strap serves to connect a mount and an upper body garment, such as a hat. The strap has sufficient stretchability to allow for natural movements of the upper body. The mount forms a snug connection to a head support on the mounting surface. The upper body garment includes a garment fastener that detachably joins with a strap garment end. In this manner, the upper body garment can be interchanged for different sizes or indicia. The garment fastener can include a hook and loop fastener. A cover overlays the garment fastener.
US09409497B1 Anti-unlock towel bar
A seat apparatus including an operating handle; a slot hole bracket including at least one inclined slot, the at least one profiled slot guides the operating handle in a horizontal direction and a vertical direction based on an inclined force on the operating handle; and one or more lock brackets movably attached to the operating handle and the slot hole bracket.
US09409496B2 Seat configured for occupancy state detection
A seat (10) configured for detecting an occupancy state comprises an at least partially electrically conductive structural frame (14) comprising at least two fixation sites (22, 24) and an at least partially electrically conductive cushion-supporting spring (20) taut between the fixation sites. The cushion-supporting spring is electrically insulated from the structural frame. The seat comprises a cushion (16) supported by the cushion-supporting spring. The cushion-supporting spring and the structural frame are disposed in such a way that they are brought in electrical contact with each other when a force (34) is applied on the cushion that exceeds a predefined threshold force.
US09409492B2 Method for precise demand response and control, and a system thereof
There is a provided a system and a computer-implemented method for reducing electric consumption by an electric vehicle connected to a charging station. The method includes: providing a wireless network for communication between an electric vehicle and a tracking server operated by a trusted entity; collecting, on the tracking server, user and location information for charging electric vehicles (EVs); receiving, at the tracking server, a demand response signal comprising consumption reduction information including sector and time period information from a utility; identifying, at the tracking server, electric vehicles charging in the sector based on each EV's location information; and transmitting, from the tracking server, a charge interruption signal to the identified electric vehicles.
US09409491B2 Parking assist system for vehicle, contactless power transmitting device, and contactless power receiving device
A parking assist system for a vehicle includes a target position setting unit setting a vehicle target parking position on the basis of a coil type and position of a power transmitting unit. When the coil type is a composite coil having a configuration such that an annular coil wound to surround a first axis and a solenoid coil wound to surround a second axis intersecting with the first axis are serially connected, the target position setting unit sets the target parking position such that a center of a power receiving unit mounted on the vehicle is located at a predetermined distance from the first axis along the second axis. The solenoid coil is set at a position with respect to the annular coil such that the first axis extends through a side face center portion of the solenoid coil.
US09409490B2 Device alignment in inductive power transfer systems
This disclosure provides systems, methods and apparatus for wireless power transfer and particularly wireless power transfer to remote systems such as electric vehicles. In one aspect, a wireless power receiver includes a first inductive element configured to receive wireless charging power from a transmitter. The wireless power receiver further includes a second inductive element, laterally separated from the first, configured to receive wireless charging power from the transmitter. The wireless power receiver further includes a position detector configured to determine a lateral position of the receiver relative to the transmitter based on characteristics of the first and second inductive elements.
US09409489B2 Automotive inductive charger with insertable magnetic core
A magnetic connector apparatus that charges an electric vehicle through contactless magnetic coupling. The magnetic connector apparatus includes an external charger, an inlet, and a magnetic connector. The inlet is connected to a rechargeable battery of the vehicle. The magnetic connector is connected to a power source of the external charger and is transferred to the vehicle to be inserted into the inlet.
US09409488B2 In-vehicle charging apparatus that charges a storage battery installed in a vehicle from a power supply provided outside the vehicle
An in-vehicle charging device is provided with: a recording unit (27) that accumulates vehicle information regarding a vehicle; a vehicle-side PLC communication control unit (26) that, when it is determined to be necessary to transmit vehicle information accumulated at the recording unit (27) to the outside of the vehicle, commands transmission of a control signal for closing an earth leakage circuit breaker (not shown in figure); and a charging control unit (25b) that transmits a control signal to the earth leakage circuit breaker on the basis of the command from the vehicle-side PLC communication control unit (26). When electrical energy is not being supplied to a storage battery (24), the vehicle-side PLC communication control unit (26) establishes PLC and batch transmits vehicle information when the earth leakage circuit breaker has been closed by the control signal transmitted from the charging control unit (25b).
US09409486B2 Control method and system of electric vehicle
A control method of electric vehicle according to an exemplary embodiment of the present invention may include a battery supplying electricity, a motor receiving electricity from the battery and generating power, and a controller controlling the battery and the motor, wherein the controller executes instructions for: detecting a torque command, a motor speed, and a motor current; calculating a motor voltage from the motor current; determining whether voltage utilization according to a speed range of the motor is higher than a predetermined value; generating an operating point correcting function according to the motor speed when the voltage utilization is not higher than the predetermined value; calculating a current command according to the motor speed from the operating point correcting function; and outputting the calculated current command.
US09409484B2 Power supply unit for a vehicle electrical system of a motor vehicle
An improved power supply unit for a vehicle electrical system of a motor vehicle, which has an a.c. generator, that provides a phase signal, having an excitation coil, a field regulator assigned to the excitation coil and a rectifier having rectifier elements for the rectification of the generator voltage supplied by the a.c. generator. The field regulator has a voltage detection range for the evaluation of the phase signal having a minimum value and a maximum value, the maximum value being adjusted to the nominal voltage of a power supply unit of the motor vehicle.
US09409483B2 Fuel cell system and vehicle fuel cell system discharging method
A fuel cell system mounted in a vehicle includes a fuel cell, a collision prediction device, a discharge device, and a controller. The fuel cell includes a gas channel to which a reactant gas is to be supplied to generate electricity. The collision prediction device is configured to predict probability of collision of the vehicle. The discharge device is configured to discharge the electricity from the fuel cell. The controller is configured to control the discharge device to discharge the electricity from the fuel cell in a case where the collision prediction device predicts that the probability of collision of the vehicle is higher than a predetermined probability.
US09409482B2 Power converter control system and method
A power converter control system includes a first power converter, at least one additional power converter, a first control module, and an additional control module. The first power converter receives direct current and outputs alternating current as a first power output. The additional power converter receives direct current and outputs alternating current as an additional power output. The first control module controls timing of events of the first power converter. The additional control module is associated with the additional power converter and controls timing of events of the additional power converter. The first control module communicates first information regarding the timing of the first power converter to the additional control module. The additional control module is configured to adjust the timing of the additional power converter to correspond with the timing of the first power converter.
US09409481B2 Apparatus and method for displaying cluster
An apparatus and a method for displaying a cluster are provided. The apparatus includes a driving sensor that senses a driving state of a mobile object and a display unit that converts a method of displaying a cluster indisposed within the mobile object. A controller is configured illuminate a scale and a pointer that indicates the scale based on the sensed driving state of the mobile object. In addition, the controller detects a current driving state of the mobile object in real time to generate a control signal with respect to the display method including a brightness degree, a brightness region, and a color of the scale.
US09409474B2 Method and system for adjusting grille shutters based on temperature and position feedback
Methods and systems are provided for adjusting vehicle grille shutters based on engine coolant temperature. In one example, a method includes adjusting grille shutters based on engine coolant temperature and additional engine operating conditions when engine coolant temperature is below a threshold and adjusting the grille shutters base on the engine coolant temperature only when the engine coolant temperature is above the threshold. Further, the method may include recalibrating a position of the grille shutters based on a grille shutter position error.
US09409473B2 Device for a drivetrain of a hybrid vehicle, drivetrain and method for operating the same
A device for a drive train of a hybrid vehicle having a planetary gear set which comprises a carrier element, a sun gear element, and a ring gear element. A first element connects to a first input shaft of a first subtransmission of a transmission, and a second element connects to an electric machine of a hybrid drive. A first shift element which couples, in a first shift position, a third of the elements to a second input shaft of a second subtransmission of the transmission, to which an internal combustion engine can be coupled, and, in a second shift position, can be coupled to another element of the planetary gear set, and having a second shift element which couples the input shafts of both subtransmissions when engaged and separates the input shafts of both subtransmissions when disengaged.
US09409469B2 Convertible top with frame locking mechanism
A convertible top of a cabriolet vehicle includes a convertible top rod assembly, which can be adjusted between a closed position spanning the vehicle interior and a storage position. The top trod assembly includes a link arrangement on both sides of a vertical longitudinal center plane of the convertible top. The link arrangement includes a main link and a main column, which are pivotably mounted on a vehicle-fixed main bearing, and a front-side first link element and a second link element, which is arranged rearward of the first link element in the closed position and is connected to the first link element by a joint arrangement. The first link element can be pivoted relative to the second link element by an actuating link extending along the second link element and can be secured against pivoting relative to the second link element in the closed position by a locking element. The locking element is mounted to rotate and interacts with a closing bolt and is adjustable between a locked position and an open position. The closing bolt is arranged on the actuating link.
US09409467B2 Vehicle with tail gate
A vehicle with a tail gate wherein the movement distance around the vehicle is reduced. In a vehicle with a tail gate, a tail gate is supported on a vehicle body such that a rear opening formed on the rear part of the vehicle body opens and closes. The tail gate has a sub opening formed on the tail gate, and a sub door for opening and closing the sub opening in the vehicle width direction. The width of the sub opening in the vehicle width direction is shorter than the width of the rear opening. One side border of the sub opening in the vehicle width direction is located in the vicinity of one edge of the tail gate in the vehicle width direction. The sub door is supported on the tail gate so as to begin to open from the side border of the opening.
US09409461B2 Air stream velocity control for ventilation system
A system and a method of controlling a ventilation or HVAC system that is configured to provide an air stream having a comfortable contact velocity to an occupant seated in a vehicle cabin. The system includes a sensor to determine the distance from a discharge nozzle to the vehicle occupant and a controller to control the exit velocity and/or an effective diameter of the nozzle. The sensor may use ultrasonic, infrared, LIDAR, or RADAR technology to determine distance. The system may determine the distance from the nozzle to the occupant based on a seat location determined by a seat location sensor. The seat location sensor may be common to an inflatable restraint (air bag) system.
US09409453B2 Tire state judging device
A tire state judging device includes wheel speed sensors configured to detect rotational speeds of tires, and a control unit configured to perform frequency-analysis of detection results of the wheel speed sensors to detect a frequency of a valley part of an output, and calculate an air pressure of the tire from the detected frequency of the valley part. According to this, the tire state judging device has an effect that this can detect a state of the tire irrespective of a state of a road surface.
US09409449B2 Spindle assembly for a tire inflation system
A spindle assembly for a tire inflation system having a spindle defining an axial direction and a fluid conduit. A rotatable part is rotatably mounted on the spindle and has a fluid passage. The fluid passage is configured to be in fluid communication with a pneumatic tire. A dynamic annular seal chamber is also provided. The annular seal chamber is disposed radially between the spindle and the rotatable part. The fluid conduit and the fluid passage are in fluid communication with each other through the annular seal chamber. The annular seal chamber is disposed axially between a first volume and a second volume. The first volume and the second volume are in fluid communication with each other through at least one fluid channel for leading fluid leaked out of the annular seal chamber and leaked into the first volume and/or into the second volume through the fluid channel.
US09409447B2 Pneumatic tire
A pneumatic tire includes a tread having at least one main groove and a plurality of ribs extending in the tire-circumferential direction. At least one of the ribs has a plurality of narrow grooves formed at intervals in the tire-circumferential direction. At least one intermittent sipe is formed corresponding to at least one of the narrow grooves. The narrow grooves are grooves each having a portion extending substantially along the tire-circumferential direction and having a groove width smaller than the at least one main groove. The at least one intermittent sipe has a plurality of holes that are intermittently formed, and at least one solid part located between adjacent two of the holes. The holes and the solid part are arranged in a direction intersecting the narrow grooves. The intermittent sipe intersects the corresponding narrow groove in the at least one solid part.
US09409443B2 Ball bearing braking apparatus
A wheel braking apparatus includes components that inhibit the rotation of a wheel when a ball bearing is placed in a braking position between a bearing wall of a non-rotating component and a bearing barrier of a hub interface component that is at least resistively connected to a hub of the wheel. In response to a wireless signal, the ball bearing is moved from a non-braking position and allowed to travel to a braking position between a bearing barrier of one side of a bearing groove and the bearing wall of the non-rotating component.
US09409442B2 Axial securing ring, bearing arrangement and production method therefor
A bearing arrangement is provided having an axial securing ring that inserts into a bearing-seat radial groove of a bearing carrier to secure an anti-friction bearing axially in relation to the bearing carrier. The axial securing ring is an open flat ring with an annular section. Radially projecting lugs are provided at each end of the annular section. The radial width of the annular section is substantially constant over the circumference of the annular section. The lugs are produced by bending the axial securing ring with respect to the annular section. The axial securing ring is plane-ground on its axial sides.
US09409439B2 Wall mounted, three dimensional, visual display element
A three dimensional visual element includes a decal or other device to simulate a crack or break within the wall on which the visual elements is mounted. The visual element also includes a functional feature, such as a light, shelf support, or electronic device. A three dimensional representation of a soccer ball is provided wherein the soccer ball is surrounded by a clear plastic decal having a cracking so as to represent cracks within the wall on which the device is mounted. Within the shell of the soccer ball, are lighting elements which allow the device to be used as a nightlight.
US09409437B2 Marker holder and eraser
A new design for a marker holder and eraser has a front side and a back side, the back side having a recess. The front side has two openings for retaining markers. A metal plate and a magnet holder are disposed within the recess and an erasing material covers the recess. Projections extend from the magnet holder into openings on the front side to engage markers disposed in the openings, thereby holding the markers at any angle.
US09409436B2 Binder apparatus
Binder apparatus are disclosed. An example binder apparatus includes a housing, first and second carrier rails supported by the housing and a slider movable between a first position and a second position. In the first position, the slider to secure the first and second carrier rails in a closed position. In the second position, the slider to enable pivotable movement of the first and second carrier rail. The binder apparatus includes a lever to pivot the first carrier rail and the second carrier rail. The lever includes a groove and a channel. The groove to receive a portion of the first and second carrier rails, the channel to receive an end of the slider. The end of the slider to move within the channel to delay movement of the slider when the lever pivots the first and second carrier rails from the open position toward the closed position.
US09409434B2 Security feature
The invention relates to a security feature with a luminescent pigment which has a host lattice doped with a luminophore and which is optically excitable to emit luminescent light. The luminescent light of the luminescent pigment has a luminescence spectrum with a first luminescence peak and a second luminescence peak whose peak intensities respectively depend on an amount fraction x of the luminophore in the luminescent pigment. In the luminescent pigment according to the invention, the host lattice and the luminophore and the amount fraction x of the luminophore are chosen such that even a slight increase or reduction of the amount fraction x of the luminophore causes a strong relative change of the peak intensities IA and IB. This increases the forgery-proofness of the luminescent pigment according to the invention.
US09409430B2 Inkjet printer
A first chamber has a plurality of first ventilation holes of a same size arranged on extended lines of a plurality of head arrays respectively. A second chamber faces the first chamber across the plurality of head arrays and has a plurality of second ventilation holes of a same size facing the plurality of first ventilation holes. Cross-sectional areas of an internal air flow passage in the first chamber at positions of the first ventilation holes decrease with an increase in a distance of the first ventilation holes from a first end of the first chamber. Cross-sectional areas of an internal air flow passage in the second chamber at positions of the second ventilation holes decrease with an increase in a distance of the second ventilation holes from a second end of the second chamber on the same side of the first end.
US09409427B2 Inkjet printer
An inkjet printer has a printing head, a sheet conveying mechanism, a carriage mounting a printing head and configured to be reciprocally movable in a printing area and non-printing area. A cap is provided to be movable between a capping position an uncap position. A controller of the inkjet printer is configured to execute a printing process, a standby process, and a capping process in which the controller causes the carriage to move to the non-printing area and moves the cap from the uncap position to the capping position. The controller causes the carriage to move into the printing area when the next printing command is received after the standby process is finished and before the carriage moving process has been completed.
US09409425B2 Tape cassette
A tape cassette that includes a housing having a top surface, a bottom surface and a front surface, a wound tape mounted within the housing, a printer head holder insertion portion that is a space extending through the housing in a vertical direction and having an oblong rectangular shape in a plan view, the oblong rectangular shape extending parallel to the front surface, and a printer first support receiving portion connected to a first end of the printer head holder insertion portion and facing the printer head holder insertion portion in a first direction that is parallel to the front surface, the first end being positioned on an upstream side of the printer head holder insertion portion in a feed direction of the tape, the printer first support receiving portion being a first indentation extending from the bottom surface toward the top surface.
US09409420B2 Recirculate and filter air to form air barrier in image forming apparatus
An image forming apparatus includes a substrate receiving member, a fluid applicator unit, and an air recirculator assembly. The substrate receiving member may selectively receive a substrate. The fluid applicator unit may selectively eject a first set of drops to the substrate received by the substrate receiving member in a print mode and a second set of drops in a maintenance mode. The air recirculater assembly may direct air to form an air barrier across the print zone to redirect at least one of aerosol and particulates from crossing through the air barrier and onto the substrate, to filter the at least one of the aerosol and particulates to form filtered air, and to form the air barrier with the filtered air.
US09409418B2 Print tape and tape printer
A reverse surface of a print tape includes a reference portion and a reference portion. The reference portion is configured to identify a position of a print area. The non-reference portion includes a plurality of through holes. The reference portion includes a barcode that includes a first mark and a second mark. The non-reference portion includes at least one first area and a second area. The at least one first area and the second area are provided to obtain a color arrangement in which the non-reference portion does not include the barcode in the lengthwise direction, where it is assumed that each of the plurality of through holes is a portion indicating both a first color and a second color.
US09409410B2 Image forming apparatus and non-transitory computer readable medium
An image forming apparatus includes a recording head, a head tank, a main tank, and a controller. The recording head includes nozzles to discharge liquid droplets. The head tank includes a liquid containing part to contain liquid supplied to the recording head. The main tank contains the liquid supplied to the head tank. The controller controls, after detection of an end state of the main tank, post-end printing using the liquid remaining in the head tank corresponding to the main tank in the end state. The controller permits the post-end printing when an amount of the liquid remaining in the head tank to which the liquid is supplied from the main tank in the end state is a predetermined threshold remaining amount or greater.
US09409407B2 Liquid ejection apparatus and tank
A liquid ejection apparatus includes a tank; a liquid ejection head; and a casing configured to integrally cover the tank and the liquid ejection head. The tank includes a container portion configured to contain a liquid, an air introducing path arranged to introduce the air into the container portion, an inlet port configured to pour the liquid into the container portion, and an outlet port formed to supply the liquid into the liquid ejection head. In an attitude that the liquid is ejectable from the liquid ejection head, the liquid is contained in the container portion such that a liquid level of the liquid in the container portion is located at a higher position than a nozzle of the liquid ejection head in a vertical direction. In the attitude that the liquid is ejectable from the liquid election head, the inlet port is covered by the casing.
US09409405B2 Method of controlling liquid ejecting apparatus and liquid ejecting apparatus
A sub-tank is pressurized by a pump, with head valves closed. Then, one of the head valves is opened to perform a first purge on a first head. After the one head valve is closed, a different one of the head valves is opened to perform a second purge on a second head different from the first head. After these purges, an open-to-atmosphere valve is opened, with the head valves closed, to decrease the pressures inside the heads which are increased by the purges. This allows a selective purge on only a head which requires a purge. As a result, the amount of ink forced out is suppressed during the pressurized purges. After the sub-tank is made open to the atmosphere, a depressurizing pump depressurizes the sub-tank to form ink menisci in the heads. This prevents air bubbles from being drawn into nozzles during the formation of the ink menisci in the nozzles after the purges.
US09409403B2 Liquid-accommodating-body accommodating receptacle, liquid supply apparatus, and liquid ejecting apparatus
A case includes a main receptacle body that accommodates an ink accommodating body which accommodates ink. A first tube support portion and second to fourth tube support portions that guide connection tubes that are connected to the ink accommodating bodies, respectively, are provided on an internal surface of the main receptacle body.
US09409400B2 Image forming apparatus configured to include nozzle face capping control
An image forming apparatus includes an apparatus body, a recording head, a maintenance unit, a cover, and a controller. The recording head has a nozzle face and nozzles in the nozzle face to eject droplets of liquid. The maintenance unit has a cap to protect the nozzle face of the recording head. The cover opens an interior of the apparatus body to an outside of the apparatus body. The controller performs a normal control to cap the nozzle face of the recording head with the cap on opening of the cover and a special control to expose the nozzle face of the recording head to an area opened by the cover on receipt of an external instruction.
US09409399B2 Muzzle for printhead assembly
A muzzle cap for a printhead assembly including a main body comprising a side wall, a top wall and a bottom wall, a vent seal disposed within an opening in the top wall, a nozzle plate seal disposed within an opening in the bottom wall, and a nozzle plate seal retainer that holds the nozzle plate seal within the opening in the bottom wall.
US09409395B2 Inkjet printing apparatus and method of making gratings
An inkjet printing apparatus and a method of making gratings are provided. The inkjet printing apparatus comprises a base; a platform provided on the base configured to carry a substrate to be processed to linearly move in a first direction on the surface of the base; and a printhead assembly provided above the platform, wherein the printhead assembly includes a printhead support and a plurality of printheads provided on a side of the printhead support facing the platform, each of the plurality of printheads is provided with a nozzle, and the printhead assembly can move linearly in the first direction. The present invention is adaptable to using inkjet printing technology to make gratings.
US09409390B1 Printing apparatus and control method therefor
According to an embodiment, a printing apparatus for printing an image on a print medium by a printhead while relatively scanning the printhead, and discharging ink from the printhead to the print medium is controlled as follows. That is, a time corresponding to a print resolution in a scanning direction of the printhead is divided into a plurality of times, and these print elements are time-divisionally driven by using the divided times as driving timings. At this time, it is controlled to form a plurality of groups each including a predetermined number of adjacent print elements of the print elements, and change the driving timings for each of the groups using the divided time as a unit.
US09409386B2 Method for cleaning a color system of a rotary printing press as well as color system
A color system of a rotary printing press includes a doctor blade device with a doctor blade chamber containing ink for a printing process, an ink reservoir from which ink is supplied to the doctor blade chamber, and a supply system which allows ink to be supplied inside the color system. The color system is connected to a storage reservoir into which ink from the color system is introduced, to a solvent reservoir containing solvent for cleaning the color system, and to a refuse container into which ink soiled by the solvent is introduced. The supply system cleans the color system by automatically pumping off ink to the storage reservoir, and automatically cleaning with the solvent, by collecting the ink in the ink reservoir and supplying the solvent to the refuse container.
US09409385B2 Intermediate sleeve
An intermediate sleeve is provided which is adapted to be mounted on a print cylinder. The intermediate sleeve includes a base layer, a reinforcing layer, a barrier layer, and a surface layer. The sleeve further includes at least one air channel extending longitudinally, circumferentially, or spirally along the interior of the sleeve, at least one air passageway extending from an inner surface of the sleeve into the air channel, and a plurality of orifices extending radially outward from the air channel to an outer surface of the sleeve. The air channel, air passageway, and orifices are in communication such that pressurized air can be supplied from the interior of the print cylinder to the outer surface of the sleeve for mounting a printing sleeve on the intermediate sleeve.
US09409383B2 Layer-specific energy distribution delamination
Delamination of a laminated multilayer stack is provided by generating a layer-specific energy distribution in the stack during delamination. A localized energy transferrer can generate localized heating, cooling heating, cooling, or other form of energy absorption or transmission, in a bonding layer of a multilayer stack. Localized energy transfer can include thermal energy transfer, such as heating and/or cooling, acoustic energy transfer, such as applying ultrasonic energy, electromagnetic energy transfer, such as applying laser light, directed microwaves, etc. Localized energy transfer can generate a layer-specific energy distribution that can weaken the bonding layer while reducing damage to other layers of the stack.
US09409379B2 Method and apparatus for bonding metals and composites
Apparatus, systems and methods for forming a structure that includes a metal and a composite material are disclosed. According to one aspect, a layer stack includes a metal layer with a first surface, the first surface including at least one protruding feature. The layer stack also includes a non-metal layer molded to the first surface of the metal layer, wherein the non-metal layer is molded over and/or around the at least one protruding feature.
US09409374B2 Double facer, and method and device for gluing thereof
A device for gluing of a double facer includes a glue bath containing glue; a gluing roll immersed in and coated with the glue; a doctor roll adjusting the glue on the gluing roll to a predetermined thickness, transferred to a single faced corrugated cardboard; a swing roll disposed at an upstream portion of a transferring direction of the corrugated cardboard; and a moving device that moves the swing roll in a direction that the single faced corrugated cardboard is wrapped around the gluing roll. The swing roll is wrapped around the single faced corrugated cardboard, and the number of flute tips of the single faced corrugated cardboard that are concurrently contacting with the gluing roll and applied with the glue is adjusted by moving only the swing roll in such a direction that crosses a sheet face of the single faced corrugated cardboard passing through the nip.
US09409372B2 Method for perforating tissue sheets
Curvilinear or other complex perforation patterns for paper products, such as paper towels and bath tissue, can be produced using a differential speed perforation nip formed between a rotating pattern roll and a moving anvil surface. The relative speed between the perforation elements on the surface of the pattern roll and the anvil surface shears the web at the perforation points.
US09409371B1 Label folding apparatus and methods for its use
A label folding apparatus and methods for its use are disclosed. Such a label folding apparatus comprises a label folding assembly and a label holding assembly, and may be used to fold a foldable label placed onto the label holding assembly.
US09409370B2 Device for producing bags from hose-shaped material
An apparatus for producing bags from tubular material having fabric made of stretched plastic strips has at least one tube-forming device or a tube-unwinding device, by which tubular material for producing bags can be produced from web-shaped material and in which the tubular material, can be conveyed in a transport direction (x′), at least one tube-separating device, by which tube pieces can be separated from the tubular material, a bottom-forming device, by which bottoms can be molded onto at least one end of a tube piece, and at least one transport device for transporting the tube pieces within the bottom-forming device in a transport direction (x) extending transversely to their direction of extension (y) The transport direction (x′) of the tubular material in the tube-forming device or the tube-unwinding device and the transport direction (x) of the tube pieces in the transport device are parallel to each other.
US09409366B1 Compactor and compacting method for a loose lightweight material
A compacting apparatus for a light weight loose material has a chamber for receiving the material and an auger for driving the material into a compression tube. During initialization, a plug in the tube impedes the material to cause a compact material plug to form which restricts further loose material in a continuous compacting action. A spring loaded restrictor partially occludes the compression tube for impeding the compacted material in a compression action to thereby form a compressed plug of the loose material continuously.
US09409361B2 Mold, molding jig and molding method
A mold (10) according to the present invention is a mold for molding a surface of a laminate (60) when curing the laminate (60) obtained by laminating prepreg (62). The mold (10) has a planar plate shape and elastically deforms from the planar plate shape into a shape corresponding to a shape of the laminate (60), thereby being capable of coming tight into contact with the laminate (60). Thereby, a mold which is easy to handle can be provided.
US09409360B2 Process for manufacturing tyres for vehicle wheels and apparatus for building a carcass structure of a tyre for vehicle wheels
A process for manufacturing tires for vehicle wheels includes building on a forming support a carcass structure including at least one carcass ply, and, at at least one end edge of the carcass ply, at least one annular anchoring structure including at least one substantially circumferential annular insert and at least one filling insert associated with the at least one substantially circumferential annular insert. Building the carcass structure includes positioning the annular anchoring structure on the carcass ply by moving the substantially circumferential annular insert into contact with an end edge of the carcass ply by means of a special positioning member, pulling down the filling insert on the end edge of the carcass ply and turning up a free end portion of the end edge of the carcass ply so as to form a turned up end portion of the carcass ply including the annular anchoring structure. The pulling down of the filling insert on the end edge of the carcass ply is carried out by a special pulling down member while the substantially circumferential annular insert is retained in a contact position with the end edge of the carcass ply by the positioning member.
US09409358B2 Composite structure core crush prevention
A composite structure includes a first laminate and a second laminate. At least one core assembly is located between the first laminate and the second laminate. The at least one core assembly includes a core component and a layer of filler material disposed at a first face of the core component. The layer of filler material at least partially fills selected cells of the core component to a fill depth such that the filler material rigidizes when cured to prevent movement and/or crushing of core component under a pressure applied during a cure cycle of the composite structure.
US09409357B1 Devices, systems, and methods for microscale isoelectric fractionation
Embodiments of the present invention provide devices, systems, and methods for microscale isoelectric fractionation. Analytes in a sample may be isolated according to their isoelectric point within a fractionation microchannel. A microfluidic device according to an embodiment of the invention includes a substrate at least partially defining a fractionation microchannel. The fractionation microchannel has at least one cross-sectional dimension equal to or less than 1 mm. A plurality of membranes of different pHs are disposed in the microchannel. Analytes having an isoelectric point between the pH of the membranes may be collected in a region of the fractionation channel between the first and second membranes through isoelectric fractionation.
US09409355B2 System and method for impregnating fiber rovings
A die and method for impregnating at least one fiber roving with a polymer resin are disclosed. The die includes an impregnation section. The impregnation section includes an impregnation zone configured to impregnate the roving with the resin. The impregnation zone includes a plurality of contact surfaces. At least one of the plurality of contact surfaces is configured such that a normal force of the roving is less than or equal to a lift force of the resin at an impregnation location on the contact surface during impregnation of the roving with the resin by the contact surface.
US09409353B2 Composite polyamide article
Uses of low molecular mass, non-evolutive polyamide resins for making composite articles are described. Articles obtained from such resins having good mechanical properties, such as rigidity, breaking load, impact resistance, and fatigue behavior in particular, even when the articles are manufactured according to cycles shorter than those usually used, and without any processing before or after the manufacture of the composite articles, are also described.
US09409351B2 Device for deposition of fibers upon a frame with concave circular sections
A device for deposition of fibers on a support (30) for producing a panel with an axis of revolution, includes a deposition head (32) and elements for positioning the deposition head relative to the support (30), with the positioning elements of the deposition head having kinematics including a first translation in a first direction (X) that is parallel to the axis of revolution, a second translation in a second direction (W) making it possible to come more or less close to the head of the support, a first rotation (C) around a first rotary axis combined with the second direction (W), and a second rotation (B) around a second rotary axis that is perpendicular to the first and second directions, wherein the kinematics of the positioning elements of the head include a third rotation (A) around a third axis of rotation that is parallel to the first direction (X).
US09409347B2 Method for forming reinforced pultruded profiles
A method and apparatus for forming a profile that contains at least one layer of continuous fibers and at least one layer of discontinuous fibers. Said method allowing the selective control of features to achieve a profile that has increased transverse strength and flexural modulus. The layer of continuous fibers may be formed from one or more continuous fiber reinforced ribbons (“CFRT”) (12) that contain fibers embedded within a thermoplastic polymer matrix, whereby a void fraction and in turn is minimized and flexural modulus is optimized Further, the ribbon (s) are consolidated so that the continuous fibers remain fixed in alignment in a substantially longitudinal direction (e.g., the direction of pultrusion). In addition to enhancing the tensile properties of the profile, the use of such ribbons also allows an improved handability when placing them into the desired position within the pultrusion die. The discontinuous fibers are also embedded within a thermoplastic matrix, in such a way as to assist in bonding of the layers to achieve the desired strength. At least a portion of the fibers are oriented in the transverse direction to provide increased transverse strength.
US09409339B2 Screw intended for the extrusion or mixing of elastomers and method for fitting same
The screw is intended for the extrusion or mixing of elastomers or plastic products. It comprises: a support, at least one sleeve having at least one relief projecting from an external face of the sleeve, and at least one split annular securing member, the member being clamped between the sleeve and the support in a radial direction with respect to an axis of the screw so as to secure the sleeve rigidly to the support. The member and the sleeve have frustoconical faces in mutual contact.
US09409334B2 Injection molding machine with purge shield
A purge shield provided on an injection molding machine includes a front plate attached to a fixed platen, a top plate extending horizontally from an upper edge of the front plate, and left and right side plates extending vertically downward from left and right side edges, respectively, of the top plate. The top plate includes a fixed plate section and a movable plate section pivotally connected by first hinges to the fixed plate section. The left side plate is pivotally connected by second hinges to the movable plate section and constitutes a lifting plate. A lower end of the lifting plate is connected by a pin to a vertical guide groove formed in the front plate.
US09409333B2 Methods of molding multi-layer polymeric articles having control over the breakthrough of the core layer
Disclosed herein are methods and systems for co-extruding multiple polymeric material flow streams into a mold cavity to produce a molded plastic article. At least one interior core stream of a first polymeric material is surrounded by inner and outer streams of at least one other polymeric material. The interior core stream serves as an interior layer of a resultant molded plastic article while the inner and outer streams serve as inner and outer layers, respectively, of the resultant plastic article. The interior core stream is selectively directed to flow into or past a downstream branch channel in a mold cavity. The downstream branch channel branches from a primary channel in the mold cavity at a branch junction. The branch channel defines a protrusion portion of the resultant molded plastic article. The leading edge of the interior core stream is selectively controlled in the branch channel to position the leading edge at or near to the terminal end of the branch channel without having the leading edge of the interior core stream breakthrough a flow-front of the inner and outer streams. The resultant molded plastic article includes an interior layer formed of the first polymeric material that extends into, through and to a distal end of the protrusion while still being encased by inner and outer layers formed from the inner and outer flow streams.
US09409327B2 Grain bin sensor cable forming method
A method and apparatus for forming a grain bin sensor cable including a plurality of mold members defining a mold cavity. A pre-formed cable with wires disposed therein is placed into the mold cavity, heated, and formed into a post-formed cable. The post-formed cable includes a recessed portion and a pair of end caps. Apertures are created within the recessed portion so as to expose a portion of the wires. The end caps are generally cone-shaped and include vertical walls. The post-formed cable is removed from the mold cavity and a sensor package is coupled to the wires exposed in the recessed portion and captured between the vertical walls of the end caps. A housing is coupled about the sensor package.
US09409323B2 Bead-forming apparatus
A bead-forming apparatus and method for its use are described. The bead-forming apparatus includes a base with a pair of legs extending from a top surface. First ends of the legs couple to respective eccentric elements. The eccentric elements removeably and rotatably couple to a platen. Second ends of the legs are rotatably and slideably mated with a gear train disposed within the base. The legs are slideably translatable into the base and the gear train maintains a rotational orientation of the legs and the eccentric elements coupled thereto. The platen is thus moveable through a circular path defined by the rotation of the eccentric elements and legs. As such, a plug of moldable material placed between the base and the platen and in contact with the platen, is formed into a double-cone shape by movement of the platen through the circular path.
US09409322B2 Single step polymerization of covalently bound multilayer matrices
A method is provided for forming complex tissue using density gradient multilayer polymerization (DGMP) to form strong hydrogels with smooth transitions between layers. The multicompartment hydrogel is formed by co-dissolving a polymer precurser with a constituent in multiple solvent fractions to a create prepolymer solutions with different densities, layering the prepolymer solutions on top of each other from high to low solvent density, and irradiating the prepolymer solutions to form a polymer. The hydrogels may be used as biomimetic matrices.
US09409317B2 Manufacturing method of bag body
A manufacturing method of a bag body that has a bag-shaped member made of an elastic and airtight material, and a granular substance filled inside of the bag-shaped member, includes a step of preparing a core for forming the bag-shaped member, by hardening the granular substance; a step of forming the bag-shaped member by forming a covering made of the elastic and airtight material around the core; and a step of breaking up the core that is inside of the bag-shaped member.
US09409315B1 Concrete power saw
A concrete saw for cutting a concrete slab incorporating a rollable trolley having upper, lateral, front, and rear ends; an engine fixedly attached to the rollable trolley, the engine having a rotary power output; a blade connected operatively to the engine's rotary power output for, upon movement of the first rollable trolley over the concrete slab, slotting said slab and drawing concrete cuttings therefrom; a shroud fixedly attached to the first rollable trolley, the shroud having a plurality of side walls, a floor, and a ceiling, the shroud housing the blade, and defining a dust containment space; a dust conveyor having input and output ends, the dust conveyor's input end being positioned within the shroud's dust containment space; power transfer pulleys connected operatively to the dust conveyor for conveying the concrete cuttings from the dust conveyor's input end to the output end; and a receptacle under the output end.
US09409314B2 Concrete power saw
A concrete saw for cutting a concrete slab incorporating a rollable trolley having upper, lateral, front, and rear ends; an engine fixedly attached to the rollable trolley, the engine having a rotary power output; a blade connected operatively to the engine's rotary power output for, upon movement of the first rollable trolley over the concrete slab, slotting said slab and drawing concrete cuttings therefrom; a shroud fixedly attached to the first rollable trolley, the shroud having a plurality of side walls, a floor, and a ceiling, the shroud housing the blade, and defining a dust containment space; an Archimedes' screw having input and output ends, the Archimedes screw's input end being positioned within the shroud's dust containment space; power transfer gears connected operatively to the Archimedes screw's for conveying the concrete cuttings from the Archimedes screw's input end to the output end; and a receptacle under the output end.
US09409311B1 Automated concrete structural member fabrication system, apparatus and method
A casting machine (722) for fabrication of precast concrete structural members (1) is disclosed, which includes side walls with integrally formed end dams (784) which are movable from an open position (78) to a closed position (80), and a bottom casting surface (88), where the bottom casting surface (788) and side walls (784) serving to form a mold (812) surrounding a cavity (108) configured to contain wet concrete (26). Concrete (26) is pumped into the cavity (108) when the self-releasing mold (812) is in closed position (80). The side walls (784) are automatically movable to the open position (78) when the concrete (26) has solidified so that a precast concrete structural member (30) is automatically released from the self-releasing mold (812). Also disclosed is a precast modular system (710) for automated concrete structural member fabrication, which includes a concrete mixing system (716), a concrete delivery subsystem (764), a block transport subsystem (720), and a plurality of casting machines (722), where each casting machine (722) includes a self-releasing mold (812).
US09409310B2 Combined feed roller and conveyor sprocket/pulley for a tree chipper
A log/tree chipper having an infeed with a roller member, such as a sprocket or pulley, guides a chain has at least one lug in the roller member, such lug extending above the outer surface of the chain and above a feed table. One or more auxiliary feed members with lugs can rotate with and along the same axis of rotation of the roller member and be spaced to one side of a roller member. The auxiliary feed member can be positioned at the material exit end of a feed table, or at both ends of a feed table. Lugs on the auxiliary feed members and/or the roller members/sprockets are, in some embodiments, positioned at the material exit end of the feed table work so as to work in a symbiotic relationship with the main feed roller.
US09409308B2 Device for separating ejection workpieces
A device is used for separating an ejection workpiece from a stub bar, and includes a fixing element, a clamp, and a mechanism arm. The fixing element fixes the stub bar. The clamp clamps the ejection workpiece. The mechanism arm connects the clamp and actuates the clamp to clamp the ejection workpiece and then rotates the clamp relative to the stub bar, such that the ejection workpiece is separated from the stub bar.
US09409307B2 Punching device
A punching device includes: a housing with a flange part and an upper part; a die part; a punch supported movably on the flange part; and two driving levers abutting against the upper part and the punch and rotatable between initial and cutting positions. Each of the driving levers has a protrusion, first and second end segments and a middle segment between the first and second segments. When the driving levers are disposed at the initial position, the middle segments overlap each other in a second direction. When the driving levers are disposed at the cutting position, the second end segment of one of the driving levers overlaps the first end segment of the other one of the driving levers in the second direction.
US09409305B2 Cutting apparatus and method
A plurality of bushings are coupled to one another via a series of bolts to provide an interlocking, articulating cutter. The bolts have a cylindrical end and a convex end. The convex ends are seated inside a concave socket coupled to the bushings. The cylindrical ends are coupled to a convex nut seated inside another concave socket coupled to an adjacent bushing. The convex ends of the bolts are configured to articulate inside the seat of the concave sockets. A washer may be placed between the bushings to provide a desired amount of flexibility and/or rigidity. The outer surface of the bushing comprises a cutting structure, such as a milled or clad cutting structure.
US09409299B2 Knife
The invention relates to a knife comprising a housing (11) and an actuator (14) that can shift a blade holder (13) carrying a blade (47) in the housing (11) between at least one safety position and at least one cutting position, the blade holder (13) being tensioned by a spring (35). The characterizing feature consists in the fact that the spring (35) is attached to the housing (11) and to a first entrainment formation (25), and that a second entrainment formation (46) is associated with the blade holder (13), which second entrainment formation can be releasably engaged with the first entrainment formation (25) such that the first entrainment formation (25) can be moved by the second entrainment formation (46) from the safety position to the cutting position by movement of the blade holder.
US09409294B1 Hierarchical geometric plan composition (HGPC) framework for robot task planning
A robot includes at least one actuator or motor and a processor configured to represent the task as a meta-node having a meta start space representing starting configurations and a meta end space representing ending configurations. The meta-node may be parallel including a first sub-node and a second sub-node each having a start space within the meta start space and an end space within the meta end space. The meta-node may also be a repetition meta-node including a third sub-node having a start space within the meta start space and an end space outside of the meta end space such that the meta end space is reached by multiple executions of the third sub-node. The processor may also simulate the task by executing the meta-node and instruct the actuator to actuate the portion of the robot based on the simulation.
US09409287B2 Hex wrench tool handle
A tool handle for releasably receiving a tool including a core portion having a base portion and a cylindrical shaft portion extending outwardly therefrom, the base portion including a first surface, a second surface, and an outer wall extending therebetween, the outer wall defining a first bore therein, and a grip portion rotatably disposed about the shaft portion of the core. The first bore is configured to releasably receive a first portion of the tool.
US09409286B2 Screw removal tool
A screw removal tool may include a tool body, a driving unit and a tool tip, wherein the tool body has a hexagonal shaft, which is connected to a cylindrical pin at a driving end, and the cylindrical pin is connected to a block, and the pin and the block are arranged in an eccentric manner at the driving end; and wherein the driving unit has an eccentric connecting hole that mates with the cylindrical pin of the tool body and the driving unit can be rotated; wherein the tool tip has an eccentric hole that mates with the block, and pressure is applied on the block to prevent the tool tip from falling out.
US09409284B2 Ratchet handle
A ratchet handle includes a detent. A front part of the detent has a first meshing portion and a second meshing portion to mesh with a ratchet gear. An accommodation recess is provided between the first meshing portion and the second meshing portion. An auxiliary member is provided in the accommodation recess. The auxiliary member has a curved surface corresponding to an outer contour of the ratchet gear. The ratchet handle further includes an operating device. The operating device is operated to turn the detent so as to control the first meshing portion or the second meshing portion to mesh with the ratchet gear. The detent of the present invention is turned with less noise and moved stably.
US09409281B2 Clamping device for a golf club head
A clamping device for use with a golf club head. The clamping device may include a base and a holding device which is rotatably coupled to the base. The holding device may include at least first and second engagement portions. Each engagement portion is configured to at least partially accommodate an iron or wedge type golf club head, and prevent such club head from moving along a plane which is defined by the holding device. The clamping device may also include first and second clamp members which are each coupled to the base so as to be alignable with and operative to firmly seat corresponding golf club head within respective ones of the first and second engagement portions of the holding device.
US09409278B2 Method and system for the ply-by-ply machining of a component made of composite material, by applying energy
The invention relates to machine a component made of composite material in order to eliminate singularities, defects or damage to the component using a method that is repeatable and adaptable. To do this, it is proposed that the defects and their type be identified by image processing of the surface of the component and that the local machining rates at which the plies are machined be regulated at the function of this identification. According to one embodiment, a system (10) for the ply-by-ply machining of defects of a component made of composite material includes a numerical data processing unit (1) combined with a sweep control (2) that commands the sweep of a high-pressure water jet machine (20), and an image formation assembly (3) including an image capturing device (30, 31) connected with the numerical processing unit (1). The processing unit (1) includes regulating devices (11, 13) indexing local sweep rates, by convergence of brightness levels (NB) from the successive sweeps, these being formed by the image capturing assembly (3) toward making the brightness uniform according to a model (Mr) correlating brightness to ply state typology identification (BT) that can be supplied by a library (4). The correlation data (BT) and brightness levels (NB) are stored in memory modules (12, 14) of the processing unit (1).
US09409276B2 CMP polishing pad having edge exclusion region of offset concentric groove pattern
The invention provides a polishing pad and a method of using the polishing pad for chemically-mechanically polishing a substrate. The polishing pad comprises at least a grooved region and an exclusion region, wherein the exclusion region is adjacent to the circumference of the polishing pad, and wherein the exclusion region is devoid of grooves.
US09409275B2 Material removal system for use with articles having variations in form
A method of removing unwanted material from an article having a variable form can include scanning the article and determining, based on the scanning, a location of the unwanted material, determining tool paths of a cutting tool which will result in removal of the unwanted material, and displacing the cutting tool along the tool paths, thereby removing the unwanted material. A material removal system for removing unwanted material from an oilfield drill bit can include a rotary indexing device which rotates the drill bit about a longitudinal axis of the drill bit, a scanning device which scans an outer surface of the drill bit, and a controller which determines a geometry of the drill bit, based on at least one scan by the scanning device, determines a location of the unwanted material, and determines tool paths of a cutting tool for removal of the unwanted material.
US09409266B2 Method and device for changing a front seal plate in an aircraft engine
Method for removing a front seal plate from an aircraft engine, the method comprising at least the following steps: a) separating a part engine unit from the aircraft engine, the part engine unit comprising the core engine and the low-pressure turbine of the aircraft engine, b) removing a front seal plate nut from the part engine unit, c) removing the front seal plate from the part engine unit.
US09409258B2 Wear member stabilization on excavator lip
A wear member stabilization system can include a wear member having recesses formed therein on opposing sides of an excavator lip receiving slot, the recesses receiving therein respective stabilization abutments which protrude outwardly from respective opposing inner and outer sides of the lip. A method of stabilizing a wear member on an excavator lip can include welding stabilization abutments to respective inner and outer sides of the lip, sliding the wear member onto the excavator lip, thereby engaging the stabilization abutments with respective recesses formed in the wear member, the stabilization abutments contacting lateral sides of the recesses between a forward end of the excavator lip and an opening extending through the excavator lip, thereby limiting lateral movement of the wear member relative to the excavator lip.
US09409253B2 Friction stir weld plugs and methods of using thereof
In one aspect of the disclosure, an article for filling an opening in an object includes a plug having a body, a first flange, and a second flange. The plug has a trailing end. The first flange is in contact with the body and extends away from the body. The second flange is in contact with the first flange and extends away from the first flange and the body. The second flange is configured to deform toward the body upon installation of the plug into the opening. This deformation of the second flange rotationally and translationally secures the plug in the opening and consolidates the plug in the opening.
US09409242B2 Machine for machining materials in blocks or slabs and machining method to be actuated through such a machine
A machine for machining materials in blocks or slabs includes: a) a tool-holder unit displaceable above an external working surface, in a parallel and orthogonal directions with respect to the working surface; b) a manipulator unit which is coupled to the tool holder unit, and includes gripping means of a material in block or slab to be worked; wherein the gripping means are moveable between a first inoperative position, which is distal with respect to the working surface, and a second operative position, which is proximal with respect to the working surface. The gripping means are rotatable between the first inoperative position and the second operative position.
US09409239B2 Drill bit
Provided is a step-shaped drill bit including at least two stepped cutting edges that are axially provided. A cutting edge of a first step from a tip is formed so as to satisfy at least one of the following conditions. That is, a number of blades is smaller, a point angle of the cutting edge is larger, or a clearance angle of the cutting edge is larger than that of cutting edges of a second and subsequent step(s). As a result, a thrust resistance during a perforation can be reduced compared with a case in which the first step cutting edge is formed such that the number of blades, the point angle of the cutting edge and the clearance angle of the cutting edge are the same as those of the second and subsequent step(s).
US09409236B2 Turning and face grooving tool having a pin clamping mechanism
A turning and face grooving tool body has a pocket and a pin. The pin has a unitary one-piece construction and an elongated shape which defines a longitudinal direction along a pin axis. The pin includes pin top and bottom ends, a pin peripheral surface which extends therebetween, and a pivot protrusion which extends outwardly from the pin peripheral surface. The pin is rotationally asymmetric about the longitudinal pin axis. The pocket includes a base surface, transverse support walls, and a pin bore which opens out to the base surface and includes a pin bore inner surface. The pin is located in the pin bore and the pin top end protrudes beyond the base surface. The pivot protrusion is spaced apart from the pin top and bottom ends, offset in the longitudinal direction from a pin midway-point which is located midway between the pin top and bottom ends.
US09409235B2 Granulation of molten material
A granulator comprising a rotary atomizer for receiving molten material and projecting droplets of the molten material there from; and an impact surface disposed within the trajectory of the droplets and upon which the droplets impact, the impact surface being at a distance from the rotary atomizer and at an angle such that (i) all or substantially all of the droplets impact the impact surface, and (ii) a substantial portion of the droplets are not fully solidified prior to contact with the impact surface.
US09409229B2 Method for continuously casting slab
A main purpose of the present invention is to provide a continuous casting method for a slab satisfying reductions of center segregation and center porosity, and inhibitions of surface cracks and internal cracks of a slab. The method includes a step of carrying out reduction on a slab having an unsolidified part by horizontal rolls and a step of alternatively carrying out reduction on the slab completely solidified by horizontal rolls and vertical rolls, wherein in the former step, reduction ratio of the slab is more than 0.5% and no more than 3% and a ratio of a width of the unsolidified part at the cross section of the slab to a width of a contact part of the slab and the rolls is 0 to 7.15, and in the latter step, each reduction ratio of the slab by the rolls is 5.4% to 6.8%.
US09409221B2 Method of hot-press forming enabling hardness control
A hardenable steel sheet is treated with press-forming by means of a die. The method is comprised of: heating the steel sheet to a temperature of an Ac3 point or higher; carrying out a primary press on the heated steel sheet so as to give a local strain to a limited part of the steel sheet; keeping the steel sheet in a state apart from the die shortly after the primary press; and carrying out a press on the steel sheet kept in the state and retain the steel sheet in close contact with the die.
US09409218B2 Extrusion piece with dissimilar ends
A method includes: determining a design for a longitudinal piece of a particular length, wherein first and second ends of the longitudinal piece have dissimilar shapes; extruding a piece that is at least twice the particular length, wherein a profile throughout the extruded piece has the first end shape; hydroforming the extruded piece to generate an expanded portion between ends of the extruded piece, wherein the ends retain essentially the first end shape; and cutting through the expanded portion to obtain a piece wherein one end has the first end shape and another end has the second end shape.
US09409215B2 Method for cleansing glass substrate and device for performing the method
The present invention provides a method for cleansing a glass substrate and a device for performing the method. The method includes: (1) providing a transport platform (20) and a glass substrate to be cleansed (40); (2) placing a glass substrate to be cleansed (40) on the transport platform (20); (3) providing two air blowing devices (60); (4) the two air blowing devices (60) blowing air flows toward the lass substrate to be cleansed (40) to have impurities (42) that are attached to the glass substrate to be cleansed (40) detached from the glass substrate (40); (5) providing a suction device (80), the suction device (80) comprising an air drawing device (82) and a magnetic attraction device (84); (6) the air drawing device (82) drawing air from the glass substrate to be cleansed (40) and the magnetic attraction device (84) generating a magnetic attraction force to magnetic impurities on the glass substrate to be cleansed (40) so as to draw the impurities (42) attached to the glass substrate to be cleansed (40) into the suction device (80).
US09409214B2 Apparatus for cleaning substrate
An apparatus for cleaning a substrate includes a suction unit generating a suction force, a suction head suctioning contamination particles remaining on the substrate that is transferred in a first direction by using the suction force, and a suction tube connected to the suction unit and the suction head so as to transfer the suction force into the suction head and providing the contamination particles suctioned by the suction head into the suction unit. The suction head may include: a plurality of suction regions arranged in a second direction crossing the first direction; and a plurality of shutters for opening and closing the suction regions. The suction regions corresponding to a width of the substrate in the second direction are opened by the shutters so as to suction the contamination particles.
US09409212B2 Nozzle apparatus and cleaning apparatus having such nozzle apparatus
A nozzle apparatus for the generation of at least one fluid stream, the nozzle apparatus comprising: a body having a nozzle chamber comprising a nozzle opening for generating a fluid stream, wherein the body is rotatably mounted on a unit and is movable about a rotation axis, wherein the nozzle opening comprises a wall and a slit-shaped nozzle mouth extending along a slit axis, and wherein the nozzle chamber opens into an opening slot formed in the wall of the body between the nozzle mouth and the nozzle chamber, fluid being fed to the opening slot through an opening in a hollow body via a stream path directed by wall sections of the nozzle chamber to the opening slot, wherein the wall sections are located opposite the opening.
US09409209B2 Injection molded screening apparatuses and methods
Screening members, screening assemblies, methods for fabricating screening members and assemblies and methods for screening materials are provided for vibratory screening machines that incorporate the use of injection molded materials. Use of injection molded screen elements provide, inter alia, for: varying screening surface configurations; fast and relatively simple screen assembly fabrication; and a combination of outstanding screen assembly mechanical and electrical properties, including toughness, wear and chemical resistance. Embodiments of the present invention use a thermoplastic injection molded material.
US09409208B2 Screen assembly
A screen assembly for grading and dewatering sand includes a frame upon which is mounted a deck having a plurality of apertures therein. The frame is mounted on a base and includes a vibration generating device for imparting vibration to the deck. The deck has a first portion inclined downwardly from a first end to second end for grading sand thereon, and a second portion for dewatering sand thereon. The first deck portion is inclined downwardly at a first angle, and the second portion is arranged substantially horizontally or inclined upwardly at a second angle. Sand may be delivered onto the deck at or adjacent the first end of the first portion, so that undersized particles of sand passing through the apertures in the first portion of the deck as oversized particles pass onto the second portion of the deck, whereby the oversized particles are dewatered.
US09409194B2 Dispensing device for a liquid with multifunction nozzle
A trigger-operated dispensing device for a liquid comprising a tang (12) applied to the exit duct, a nozzle (30) applied to a tang, an insert (60) applied to the nozzle (30), axially bound and rotatable around the dispensing axis (X), provided with two openings (62, 64) for dispensing the liquid as a spray or as a foam. The insert (60) comprises an obturator (68), shaped to close/open the device.
US09409190B2 Pressure washing system for wet wells
Herein is disclosed an in-situ system for automatically washing the walls of a wet well. The system includes a high pressure water pump coupled to a plurality of elongated high pressure water spray heads mounted along the walls of the wet well. The high pressure water spray heads are each coupled to the water pump via a solenoid valve which is in turn coupled to a control panel. The control panel is configured to operate the spray heads one at a time so that the wet well is washed by operating only one spray head at a time. The system uses standard municipal water line as a water source and uses inexpensive motors, pumps and fittings.
US09409189B2 Modular cyclonic separator for separating solid impurities from an airflow
A modular cyclonic separator comprises separating tubes each including an air-guiding impeller that is fixed coaxially in an outer tube body and that is formed with spiral channels for causing an airflow, which flows radially into the separating tube, to follow a cyclonic flow pattern through a separating chamber in the separating tube, thereby separating some of solid impurities from the airflow within the separating chamber. Each separating tube is capable of connecting selectively with one or two three-port valves to form a first or second filtration module, in which the airflow passes through a fluid passage in the one three-port valve or one of the two three-port valves prior to entering the separating tube.
US09409188B2 Trickle valve assembly and a method of supplying particulate material through such trickle valve assembly
The present invention concerns a trickle valve assembly for supplying particulate material exiting the bottom of a separating cyclone, comprising a separating cyclone outlet conduit having a bottom end with an inclined valve seat and a pivotable valve plate assembly with a valve plate pivoting about a valve hinge and a counter-weight on the opposite side of valve hinge, wherein the outlet conduit is provided with at least one gas inlet above the inclined valve seat which is in fluid communication with a supply of pressurised gas, such as a pressurised air supply.
US09409184B1 Portable sand plant, systems and methods
A portable plant, systems and methods for processing material, the plant having a chassis configured to connect to a truck to transport the plant on a roadway, the chassis having wheels and a base frame, an uppermost portion of the base frame positioned below an uppermost portion of the wheels, a first material processing device such as a hydrosizer mounted to a tower structure, the tower structure rotatably fixed to the base frame, and a hydraulic cylinder connected to the base frame and to the tower structure where operation of the cylinder causes the hydrosizer and the tower to adjust between a generally horizontal orientation where the hydrosizer is generally horizonatally oriented or rests on the base frame and a generally vertical orientation. The hydrosizer may be a cone-shaped hydrosizer and the wheels may be associated with a removable suspension and the chassis is configured to rest on the ground and receive additional processing components for use in a processing mode where the additional components are placed on a position of the chassis vacated by the elevated first material processing device.
US09409183B2 Pump and submersible solids processing arrangement
A pump and submersible solids processing arrangement includes a pump, having a suction inlet and discharge, and a submersible solids processing arrangement positioned in fluid communication with the suction inlet of the pump and being structured to macerate larger solids and matter that is entrained in a fluid to thereby reduce the size of the solids prior to entry of the fluid and solids into the inlet of the pump, the arrangement further including macerating members the speed and arrangement of which are selectively determinable or adjustable, and the arrangement further comprising an agitator arrangement for directing solids into the submersible solids processing arrangement.
US09409176B2 Sample container with physical fill-line indicator
A collection container for collecting biological fluid specimens having an integral fill-line indicator which corresponds to a desired specimen volume is disclosed. The integral fill-line indicator may comprise a ridge that is raised from the surface of the collection container. The integral fill-line indicator may also be altered by surface modification to impart a distinct visual appearance and/or texture. The collection container may have a single or a plurality of integral fill-line indicators which correspond to a desired specimen volume range. A method of manufacturing a collection container having an integral fill-line indicator is also disclosed.
US09409175B2 Mixing apparatus
A mixing apparatus includes: a mixing container with a discharge port for discharging mixed liquid; a filter paper covering the discharge port to temporarily retain the liquid; a receiving unit with a waste liquid collecting portion for receiving a first liquid discharged from the discharge port through the filter paper, and a measuring portion for receiving a second liquid subjected to treatment different from treatment for the first liquid; and an operation portion for enabling selection between a first receiving state in which the waste liquid collecting portion receives the first liquid and a second receiving state in which the measuring portion receives the second liquid, and also for controlling the movement of the first liquid or the second liquid.
US09409174B2 Microfluidic system with fluid pickups
Microfluidic system, including methods and apparatus, for processing fluid, such as by droplet generation. In some embodiments, the system may include a well and a channel component attached to the well. The channel component may include (a) a body, (b) an input tube (a “fluid pickup”) projecting from a bottom surface of the body and having an open bottom end disposed in the input well, (c) a microchannel, and (d) a passage extending through the input tube and the body and connecting the well to the microchannel. The system may be configured to receive a sample-containing fluid in the well and retain the sample-containing fluid below a top end of the passage, until a pressure differential is created that drives at least a portion of the sample-containing fluid from the well via the passage and through the microchannel.
US09409172B2 Microchip and channel structure for the same
A microchip includes a channel permitting a sheath liquid to flow therethrough; and a microtube for introducing a sample liquid into a laminar flow of the sheath liquid flowing through the channel; wherein liquid feeding is performed in the condition where a laminar flow of the sample liquid introduced through the microtube is surrounded by the laminar flow of the sheath liquid.
US09409169B2 Microfluidic card connection device
A device for interconnecting a card including at least one first fluid channel, emerging from a connection side parallel to a support side, the interconnection device including: a first surface configured to receive the support side of the card; a second surface parallel to the first surface, from which a second fluid channel emerges; and a mechanism to hold the card in place, configured to hold a connection side of the card pressed against the second surface of the device, such that first fluid channel is in fluid connection with the second fluid channel.
US09409166B2 Integrated PCR reactor for cell lysis, nucleic acid isolation and purification, and nucleic acid amplication related applications
Disclosed are integrated devices capable of performing a polymerase chain reaction within a single vessel. Also disclosed are related methods of sample analysis.
US09409161B2 Catalyst and method for its preparation
A catalyst including gold, or a compound thereof, and sulphur, a compound of sulphur, trichloroisocyanuric acid or a metal dichloroisocyanurate on a support, together with a process for manufacturing the catalyst and its use in a chemical process are described.
US09409157B2 Catalyst for reforming hydrocarbons
Provided is a catalyst for preparing a syngas by reforming methane wherein a nickel-based catalyst is mixed with a metal oxide catalyst. More particularly, alumina is used as a support and a metal oxide catalyst including magnesia, nickel, vanadium, tungsten, iron, molybdenum or chromium is used to inhibit carbon deposition and maintain or improve catalytic activity.
US09409155B2 Metal structure catalyst and preparation method thereof
Provided are a metal structure catalyst and a method of preparing the same. Particularly, the method includes forming a metal precipitate on a metal support by contact of a mixed solution including a precursor of a metal catalyst and a precipitating agent with the metal support, and forming metal particles by thermally treating and reducing the metal precipitate formed on the metal support. The metal structure catalyst includes a metal support, a metal oxide layer formed on the metal support, and metal nanoparticles formed on the metal oxide layer. In addition, the metal nanoparticles are uniform and have enhanced binding strength.
US09409149B2 Sulfur resistant cladded titania—alumina supports
The present invention is directed to a method of forming titania clad high surface area alumina suitable as a support for forming noble metal catalysts. The resultant catalysts exhibit resistance to poisoning by sulfurous materials and, therefore, are useful in applications directed to internal combustion engine emission conversion and the like. The present invention provides a commercially feasible and cost effective method of forming a highly desired support for noble metal catalyst application. The process comprises forming a slurry of porous alumina particulate suitable as a catalyst support for the intended application, mixing said slurry with a solution of titanyl sulfate having a pH of about 1, increasing the pH of the mixed slurry/solution at a slow rate of from 0.05 to 0.5 pH unit per minute to a pH of ≦4 by the addition of a basic solution, allowing the resultant slurry to age for a period of from 10 to 120 minutes, separating the treated porous alumina particulates and washing same free of sulfate with a weak base, drying and calcining said particulates to produce titania clad alumina particulate product. The resultant material exhibits a normalized sulfur uptake of less than about 45 μg/m2-sample. Such material can subsequently be coated with a noble metal to form the catalyst material.
US09409147B2 Method for granulation of absorbent and adsorbent granules prepared by the same
The present invention relates to a method for granulation of an absorbent and adsorbent granules prepared by the same. The method comprises the steps of blending sodium metasilicate, metakaoline and an inorganic ion exchange material in water to form a slurry; decanting the resulted slurry onto a nylon cloth of 300 to 400 meshes and natural drying at ambient temperature to solidification; then breaking the solidified final product and sieving it by a screen having a mesh size of from 0.2 to 2.5 mm to provide the absorbent granules having excellent absorbability.
US09409144B2 Cation adsorbent for solution treatment
A cation adsorbent of an embodiment includes tungsten oxide particles having a BET specific surface area in a range of 0.82 m2/g or more and 820 m2/g or less. The cation adsorbent is added to a solution to be treated containing cations being recovery objects, and the cation adsorbent adsorbing the cations is precipitated. The generated precipitate is separated from the solution to recover the cations.
US09409142B2 Method and device for the synthesis of artemisinin
The present invention is directed to a method for producing artemisinin having the formula from dihydroartemisinic acid in a continuous flow reactor using singlet oxygen as well as to the continuous flow reactor for producing artemisinin.
US09409141B2 Methods for synthesizing metal oxide nanowires
A method of synthesizing a metal oxide nanowire includes the steps of: combining an amount of a transition metal or a transition metal oxide with an amount of an alkali metal compound to produce a mixture; activating a plasma discharge reactor to create a plasma discharge; exposing the mixture to the plasma discharge for a first predetermined time period such that transition metal oxide nanowires are formed; contacting the transition metal oxide nanowires with an acid solution such that an alkali metal ion is exchanged for a hydrogen ion on each of the transition metal oxide nanowires; and exposing the transition metal oxide nanowires to the plasma discharge for a second predetermined time period to thermally anneal the transition metal oxide nanowires. Transition metal oxide nanowires produced using the synthesis methods described herein are also provided.
US09409136B2 High pressure feeder and method of operating to feed granular or fine materials
A coal feed system to feed pulverized low rank coals containing up to 25 wt % moisture to gasifiers operating up to 1000 psig pressure is described. The system includes gas distributor and collector gas permeable pipes imbedded in the lock vessel. Different methods of operation of the feed system are disclosed to minimize feed problems associated with bridging and packing of the pulverized coal. The method of maintaining the feed system and feeder device exit pressures using gas addition or extraction with the pressure control device is also described.
US09409133B2 Assembly for the production of dispersions
An assembly for the production of dispersions including a mixing unit (7) and a circulation tank (1) for holding liquid, the mixing unit (7) including a first solid inlet (8) for receiving a solid, a second liquid inlet for receiving the liquid, a mixing chamber where the liquid and solid are mixed, and a return outlet (13), the liquid inlet is fluidly connected to the circulation tank (1) such that liquid in the circulation tank flows to the mixing unit (7) via a circulation tank outlet (4), the return outlet (15) transferring the combined liquid and solid from the mixing chamber (7) into the circulation tank (1) via a circulation tank inlet. The circulation tank has an interior height which is configured such that a chamber exists inside the tank above the level of the liquid. Alternatively, the circulation tank inlet is permanently positioned above the liquid level or it includes a pipe configured such that the dispersion forms a film on its inner surface. Alternatively, the circulation tank includes an impeller having a diameter equal to or greater than 0.5 times the internal diameter of the tank.
US09409128B2 Methods for storing red blood cell products
Methods and systems for processing and conditioning red blood cells are disclosed. The methods and systems may be used to make a readily transfusible red blood cell product with reduced plasma. In general, the plasma content of the supernatant of the red blood cell product is no greater than about 15%. The red blood cell products are prepared using the disclosed methods and systems remain transfusible for up to 42 days.
US09409127B2 Honeycomb structure and method for manufacturing the same
A honeycomb structure includes a tubular honeycomb structure body including porous partition walls defining a plurality of cells, and an outer peripheral wall and a pair of electrode parts disposed on a side face of the honeycomb structure body, wherein the honeycomb structure body has electric resistivity of 1 to 200 Ωcm, each electrode part has a belt-like shape extending in an extending direction of the cells, each electrode part is placed on an opposite side each other across a center of the honeycomb structure body, the honeycomb structure body includes an inflow-side area that is an area on the inflow-side and covering the inflow end face, and an outflow-side area that is an area other than the inflow-side area, and the inflow-side area is made of a material having electric resistivity lower than electric resistivity of a material of the outflow-side area.
US09409124B2 Flow control grid
A flow control grid includes a plurality of channel assemblies connected to one another. Each of the plurality of channel assemblies defines a flow straightening section and a flow turning section. The flow turning section has an arcuate segment and a first substantially flat segment. The first substantially flat segment is positioned in the flow straightening section. The arcuate segment extends outwardly from the flow straightening section.
US09409123B2 Control of wet scrubber oxidation inhibitor and byproduct recovery
The present disclose is directed to a method for controlling iodine levels in wet scrubbers, and, in particular, recirculating wet scrubbers by removing the iodine from the scrubbing solution, such as by using ion exchange, absorption, adsorption, precipitation, filtration, solvent extraction, ion pair extraction, and an aqueous two-phase extraction.
US09409120B2 Hybrid process using a membrane to enrich flue gas CO2 with a solvent-based post-combustion CO2 capture system
A process for recovery of CO2 from a post-combustion gas includes pre-concentrating a CO2 component of the post-combustion flue gas by passing the post-combustion gas through a CO2-selective membrane module to provide a CO2-enriched permeate stream and a CO2-lean reject stream. Next, in a CO2 absorber, both the CO2-enriched permeate stream and CO2 lean reject stream, fed to separate feed locations on the CO2 absorber, are contacted with a scrubbing solvent to absorb CO2 and provide a carbon-rich scrubbing solvent. Finally, absorbed CO2 is stripped from the carbon-rich scrubbing solvent by a two-stage CO2 stripping system. The CO2-selective membrane may be a high flux, low pressure drop, low CO2 selectivity membrane. The two stage stripping system includes a primary CO2 stripping column for stripping CO2 from the carbon-rich scrubbing solvent exiting the CO2 absorber, and a secondary CO2 stripping column for stripping CO2 from a carbon-lean scrubbing solvent exiting the primary CO2 stripping column. Apparatus for CO2 removal from post-combustion gases in a pulverized coal power plant incorporating the described processes are described.
US09409118B2 Carbon oxide capture
The present invention relates to the use of (poly)-oxymethylene dialkyl ethers as agents for capturing carbon oxides, CO and/or CO2.The invention also relates to the process for capturing carbon oxides using at least one absorption agent chosen from said (poly)oxymethylene dialkyl ethers.
US09409117B2 Air pollution control system, air pollution control method, spray drying device of dewatering filtration fluid from desulfurization discharged water, and method thereof
To include a boiler 11 that burns fuel F, an air heater 13 that recovers heat of flue gas 18 from the boiler 11, a first precipitator 14 that reduces dust in the flue gas 18 after heat recovery, a desulfurizer 15 that reduces sulfur oxides in the flue gas 18 after dust reduction by an absorbent, a dewaterer 32 that reduces gypsum 31 from desulfurization discharged water 30 discharged from the desulfurizer 15, a spray drying device 34 including an atomizer that atomizes a dewatering filtration fluid 33 discharged from the dewaterer 32, and a flue-gas introducing line L11 that introduces a part of the flue gas 18 into the spray drying device 34.
US09409114B2 Replacement filter with cartridge and automatic filter media advance and wireless communications
A replacement filter deployed within a flow channel with a housing having a first of two or more frame members and a second of two or more frame members that are detachable with an exposure slot formed within the housing. A filter media storage area is within the housing, having unexposed, folded, pleated filter media stored therein. The unexposed folded, pleated filter media is compactly held within the filter media storage area. A motor is coupled to a power supply and in communication with a controller. The motor moving a movement member that advances an unexposed portion of the stacked pleated filter media into the exposure slot, expanding and exposing the unexposed portion of the media to the flow channel while retaining pleats and creating an exposed portion of the filter media. A containment area is provided where the exposed portion of the pleated filter media is collected folded, restacked and compactly stored and retained.
US09409112B2 Air filter element
An air filter element has a filter means and a circumferential plastic frame with a sealing element, which encompasses a laterally outwardly projecting border of the plastic frame in a U-shaped manner. The sealing element is one piece with a circumferential sealing lip that is arranged on a side flank of the U-shaped sealing section.
US09409111B2 Porous block nanofiber composite filters
Porous block nano-fiber composite (110), a filtration system (10) and methods of using the same are disclosed. An exemplary porous block nano-fiber composite (110) includes a porous block (100) having one or more pores (200). The porous block nano-fiber composite (110) also includes a plurality of inorganic nano-fibers (211) formed within at least one of the pores (200).
US09409110B2 Method of maintaining water quality in a process stream
Disclosed and claimed is a method of removing contaminants from a process stream or stabilizing a system parameter in the process stream. The method includes providing a filtration system in communication with a controller, wherein the controller is operable to automatically initiate a flow from the process stream into the filtration system when the system parameter of the process stream is within above an upper threshold value and/or below a lower threshold value; and activating the filtration system, wherein the flow comprises a flow rate through the filtration system and the controller is operable to adjust the flow rate.
US09409109B2 Filtration container
A filtration container for concentration of macromolecules is insertable into a filtrate recovery tube (5) and has an upper portion (2), a central portion (3) axially adjoining the upper portion (2), and a lower portion (4) axially adjoining the central portion (3). The upper portion (3) forms a hollow-cylindrical sample container (7) with an inlet opening (9) on its upper end face (8). The downwardly tapering central portion (3) has a filtration chamber (11) with two mutually opposed main walls (12, 13) running down toward one another. At least one of the main walls (12, 13) has a filter window (16) for receiving a planar membrane filter (17). The lower portion (4) forms a retentate chamber (21) adjoining the lower edge (18) of the filter window (16) A base (26) of the retentate chamber (21) slopes down on one side laterally.
US09409108B2 Modular filter capsule apparatus
Disclosed is a disposable filter capsule apparatus that incorporates integral quick connect components and check valves to facilitate assembly to, and dis-assembly from, larger assemblies and apparatus. The quick connect elements and valves are configured to eliminate the need for auxiliary sealing elements, e.g., o-rings and valve springs so as to prevent unwanted reactions with fluids and/or gases flowing through the capsules, and to further prevent the disposal of expensive re-usable elements in the disposable capsules.
US09409106B2 Fluid filtration and particle concentration device and methods
Fluid filtration devices and methods of filtering fluids are described. The devices generally include a housing and an annular filter assembly, wherein the filter assembly is located inside the housing and comprises a filter material. The filter material may be, for example, an electroformed nickel screen having a smooth working surface and expanding pores. A rotating cleaning assembly comprising a distributor and wipers may be located inside the filter assembly.
US09409103B2 External device for cleaning filtration material and adapted for application to filtration device
An external device for cleaning a filtration material is applied to a filtration device for filtering a supplied unfiltered liquid by layers of a filtration material to remove muddiness in the liquid and discharging the cleaned liquid to the outside. The cleaning device has an upstanding outer tube, a screw conveyor rotatably placed in the outer tube and transferring the filtration material upward from the lower rod to the upper end of the outer tube while rub-washing the filtration material, a drive section for rotationally driving the screw conveyor, a control section for controlling rotation of the drive section, and a discharge tube for discharging the filtration material having been rub-washed, into a filtration container from the inside of the outer tube and an introduction tube that introduces the filtration material into the outer tube.
US09409101B1 Multi-sensory module array
A multi-sensory module array system for enhancing the experience of members of the audience at entertainment events through the stimulation of a plurality of the senses of sight, sound, touch, taste and smell independent of their location or proximity to a live or recorded performance at one or more venues. In one aspect, the multi-sensory module array system includes a first zone having a first set of multi-sensory entertainment module spaced apart from each other and defining a first diamond configuration, wherein the modules are configured to emit one or more sensory outputs within the first zone. The system can further include a second zone having a second set of multi-sensory entertainment modules spaced apart from each other and defining a second diamond configuration and further configured to emit the sensory outputs within the second zone. Here, at least one of the modules can be shared between the first set and second set. In addition, the amplitude or magnitude of the sensory outputs within the first zone can be substantially the same with respect to the second zone.
US09409096B2 Adjustable toe suspension arm
The present embodiments provide an adjustable toe suspension arm for a vehicle. The suspension arm includes a main suspension bracket coupled to the vehicle's chassis. An outer swing bracket is pivotably coupled to the main suspension bracket. An adjustment mechanism is coupled to the main suspension bracket. A sliding nut is coupled to the adjustment mechanism. A portion of the sliding nut is contact with the outer swing bracket. When the adjustment mechanism is manipulated, the sliding nut moves to rotate the outer swing bracket with respect to the main suspension bracket.
US09409094B1 Slide system
The slide system includes a plurality of slide segments that are detachably and longitudinally inter-coupled, each slide segment having a length, a width, and a sliding surface. The slide system also includes a plurality of transverse arches, each transverse arch spanning at least a portion of the width of one of the slide segments. Still further, the slide system includes a water distribution subsystem that has a water supply interface that is coupleable in water receiving communication with a water source and water routing lines that are coupled in water receiving communication with the water supply interface. The water routing lines are coupled to the plurality of transverse arches and comprise outlets that distribute water transversely across at least the portion of the width of the sliding surface of the slide segments.
US09409093B2 Gaming device with modular gaming table components
Provided in embodiments of the present invention is a gaming device having a plurality of dynamically connectable modular gaming table components that provide a variety of configuration options. In one example embodiment, the gaming device includes a first modular gaming table component and a second modular gaming table component, where the first modular gaming table component and second modular gaming table component are 10 connectable in a variety of arrangements. Each of the first and second modular gaming table components may include at least one gaming station having a gaming display, gaming control circuitry, structural connection means, and communication connection means, whereby the structural and communication connection means of the two components may be dynamically connectable in a variety of component arrangements.
US09409091B2 Baseball videogame having pitching meter, hero mode and user customization features
A sports videogame such as a baseball videogame allows a user to control the release time of a pitch in order to control the timing of a break on the pitched ball. Other implementations of a baseball videogame allow a user to put extra spin on a pitched ball to thereby create a greater break on the pitch or allow the user to play in a hero mode which enables the user to control a videogame character in a series of specific game play scenarios designed to allow the user to immediately control the videogame character to perform unique skills. Game play may also be customized by allowing the user to incorporate user-created images into screens of game play and/or allow the user to incorporate recorded audio messages into game play.
US09409089B2 Method for implementing a computer game
A method, implemented as computer code being executed by one or more processors, in which a computing device displays computer game graphics showing a score for a computer game, and in which, one or more of the processors are programmed to: (a) receive the score a player achieves while playing a game; and (b) visually indicate how this score relates to one or multiple pre-defined goals; (c) receive information about the high scores of different players of the game (d) compare the current score of the player, the previous high score of the player and the high scores of the different players; and (e) during the play of the game, visually represent the difference between the current score, the high scores of the different players and the pre-defined goal(s).
US09409082B2 Apparatus and medium for controlling a rhythm game with an editing function
A rhythm game control apparatus for controlling progress of a rhythm game is provided. Basic music score information indicating a basic music score on which a trigger arrangement permissible mark is arranged and music score information indicating a music score are stored. A display device is caused to display a music score editing screen on which the basic music score can be edited. The trigger is arranged on the basic music score in accordance with a trigger arranging request received from a player when an arranging request position of the trigger by the trigger arranging request is an arrangement permissible position at which a trigger arrangement permissible mark is arranged. The music score information is registered in the music score information memory indicating the music score for which the trigger is arranged on the basic music score and the basic music score is thereby edited.
US09409081B2 Methods and systems for visually distinguishing objects appearing in a media asset
Methods and systems are described herein for a media application that indicates to a user when members of his or her fantasy sports team appear in sports programming displayed on a user device. In addition, the media application may display additional information (e.g., statistics, commentary, highlights, etc.) that is particular to members of the fantasy sports team of the user.
US09409080B1 Educational ball
An educational ball has a body and multiple operating sets. The body is a square block and has six outer surfaces, six mounting recesses respectively formed in the outer surfaces, and six engaging holes respectively formed through the mounting recesses. The operating sets are connected to the body, are respectively and rotatably mounted in the mounting recesses, and each one of the operating sets has a rotating mount, two covering plates, a sliding groove, and multiple sliding sheets. The rotating mount is rotatably mounted in a corresponding mounting recess, and has an engaging jacket and two inserting holes. The covering plates are connected to the rotating mount, and each covering plate has a connecting pipe, multiple track grooves, and a guiding channel. The sliding sheets are movably mounted in the track grooves of the covering plates and the sliding groove of the operating set to cover the rotating mount.
US09409075B2 Golf practice device
A golf practice device, for practicing the back swing of a golf swing, includes a folding device, which can be arranged so as to be inclined against the horizontal about a predetermined angle. The angle is the angle of inclination of the swing plane of the back swing. The device also includes a trigger device, which cooperates with the folding device. The trigger device is adapted to lock the folding device in the predetermined angle in a locked mode and to release the locking of the folding device in a trigger mode. The folding device can be folded downwards about a pivot axis in response to releasing the locking device.
US09409073B2 Golf clubs and golf club heads
Golf clubs according to at least some example aspects of this disclosure may include a golf club head and a shaft configured to engage with the golf club head which includes a grip engaged with the shaft. Further, the golf club may include a monitoring device, which includes a sensor and a transmitter. Additionally, the monitoring device may be configured to determine data related to the characteristics of a golf swing. Further, the monitoring device may be configured to transmit the data related to the characteristics of a golf swing to a remote computer.
US09409072B2 Football sled with blocker pad range of motion
A blocking sled includes a sled frame, an arm mounted to said sled frame and a blocking pad having at least one handhold mounted to the arm.
US09409068B2 Adjustable golf club and system and associated golf club heads and shafts
In general, aspects of this invention relate to golf clubs or golf club components incorporating adjustment members that permit ready adjustability of golf club parameters and/or interchangeability of golf club components to change a golf club configuration, and methods for providing golf clubs. According to aspects of this invention, an adjustment member may be utilized to allow the adjustability of a golf club parameter to change a golf club configuration, while ensuring there is substantially no change to other club or club head variables, parameters or characteristics. According to another aspect of this invention, an adjustment member may be utilized to allow the adjustability of two golf club parameters independently to change a golf club configuration, while ensuring there is substantially no change to other club or club head variables, parameters or characteristics.
US09409067B2 Golf club head with flexure
A golf club head including a crown, a sole, a hosel, a face and a flexure. The flexure provides compliance during an impact between the golf club head and a golf ball, and is tuned to vibrate, immediately after impact, at a predetermined frequency.
US09409066B2 Golf club head and face insert
A face insert for golf club head in one embodiment can comprise a substrate comprising a score line groove-free front surface. A cover layer is provided at least on the front surface of the substrate. The cover layer can alternatively overlay at least a portion of the peripheral edge of the substrate. The cover layer comprises a ball-striking surface spaced by the cover layer from the substrate. Plural elongated score line grooves can extend into the polymer layer from the ball-striking surface. In addition, visible markings are interposed between the cover layer and the front surface of the substrate, the visible markings being visible through the cover layer. In one form the visible markings comprise elongated score line markings and target markings in a central portion of the substrate. The visible markings can be screen-printed markings, which are then protected by the cover layer from wear. The cover layer can be molded and can be a polymer layer. The score line grooves can be formed, for example, by molding during molding of the polymer layer.
US09409064B2 Golf ball having an aerodynamic coating including micro surface roughness
Golf balls include: (a) a golf ball body having a first set of construction specifications and a first dimple pattern formed on an outer surface of the golf ball body; and (b) a coating applied to the outer surface of the golf ball body to thereby produce a coated golf ball body having an exterior surface. At least one of the outer surface of the golf ball body and the coating includes a plurality of surface roughening particles to provide increased micro surface roughness as compared to golf balls having the same set of construction specifications and the same dimple pattern but without the micro surface roughening particles. The micro surface roughening affects the aerodynamic properties of the ball.
US09409045B2 Solid propellant fire extinguishing system
A fire extinguishing system comprises a hermetically sealed storage canister (110) fabricated with at least one gas outlet (111) and defining a hollow (112) within; a powder form fire extinguishing agent (120) stored inside the canister (110): a solid propellant (130), which is ignitable to generate gases (135); connected to the canister (110); and a rupturable seal (140) disposed at the gas outlet (111), wherein the solid propellant (130) generates gasses to aerate the fire extinguishing agent (120) inside the canister (110) and build a positive gas pressure until the gas pressure is sufficient to rupture the seal (140) for discharging the fire extinguishing agent (120) under pressurized gas flow (150).
US09409044B2 Modular turnout gear
A modular garment includes a sleeved jacket and a vest that may be worn by a first responder. The sleeved jacket is constructed for use in some emergency circumstances, including technical rescue operations. Portions of the jacket, including at least portions of the sleeves, may be constructed to satisfy more stringent garment standards, such as garment standards for structural firefighting. A vest may be worn over the sleeved jacket to produce a combined jacket suitable for use as turnout gear in structural firefighting.
US09409036B2 Implantable connector systems having magnetic portions thereon and related methods
A connecting system includes an implantable base unit having an implantable housing with an externally accessible magnetic portion and an implantable unit connecting member. The implantable base unit is configured to be at least partially implanted in a subject such that the externally accessible magnetic portion is accessible from an external region of the subject. An interface unit is releasably coupled to the implantable base unit. The interface unit has an interface housing with an interface magnetic portion and an interface unit connecting member. The interface magnetic portion is configured to engage the externally accessible magnetic portion of the implantable base unit to mechanically couple the implantable unit connecting member and the interface unit connecting member.
US09409034B2 System, method and apparatus for analyzing cardiac rhythm during CPR
A diagnostic medical device for identifying an arrhythmia treatable by a defibrillation shock includes a defibrillating a filter for filtering ECG data sets, a classifier and a electrotherapy circuit. The classifier is configured to classify filtered and unfiltered ECG data sets as a “shock” advice or a “no-shock” advice.
US09409026B2 Lead monitoring frequency based on lead and patient characteristics
A method and device for updating a frequency of determining whether a lead condition is occurring in a medical device that includes sensing a cardiac signal, determining whether a lead condition is occurring in response to the sensed cardiac signal, determining a patient characteristic, and updating a frequency of determining whether the lead condition is occurring in response to the determined patient characteristic.
US09409024B2 Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction
Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone. This neural fulcrum zone corresponds to a combination of stimulation parameters at which autonomic engagement is achieved, while the tachycardia-inducing stimulation effects are offset by the bradycardia-inducing effects, thereby minimizing side effects such as significant heart rate changes while providing a therapeutic level of stimulation.
US09409023B2 Spinal stimulator systems for restoration of function
Described are devices including stimulation assemblies connectable to a plurality of electrodes. The plurality of electrodes can be configured to connect to a spinal cord at a location below a lesion of the spinal cord. The stimulation assembly can be configured to deliver stimulation to selected ones of the plurality of electrodes when the stimulation assembly is connected to the plurality of electrodes when located below the lesion of the spinal cord. Methods of using the devices are also described.
US09409022B2 Methods and systems for stimulating a motor cortex of the brain to treat a medical condition
Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.
US09409015B2 Method and apparatus for generating an electrode stimulation signal in a neural auditory prosthesis
An auditory stimulation signal processing has a plurality of signal inputs adapted to receive a plurality of frequency bin signals, a selection probability value assigner, a random selector, and an electrode stimulation signal generator. The selection probability assigner is adapted to assign a selection probability value to at least one frequency bin signal of the plurality of frequency bin signals. The random selector is adapted to select one frequency bin signal from the plurality of frequency bin signals by means of a random process taking into account the selection probability value assigned to the at least on frequency bin signal. The electrode stimulation generator is adapted to generate an electrode stimulation signal for application to an electrode of a neural auditory prosthesis, the electrode corresponding to a frequency of the selected frequency bin signal. A corresponding method and a computer readable digital storage medium are also disclosed.
US09409013B2 Method for controlling energy delivery as a function of degree of coupling
A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
US09409011B2 Method of constructing an implantable microelectrode array
An implantable electrode array assembly configured to apply electrical stimulation to the spinal cord. A substantially electrically nonconductive layer of the device has a first portion positionable alongside the spinal cord that includes a plurality of first openings. The layer has a second portion that includes a plurality of second openings. Electrodes and traces are positioned inside a peripheral portion of a body portion of the device and alongside the layer. At least one of the first openings is adjacent each of the electrodes to provide a pathway through which the electrode may provide electrical stimulation to the spinal cord. At least one of the second openings is adjacent each of the traces to provide a pathway through which the trace may receive electrical stimulation. At least one trace is connected to each electrode and configured to conduct electrical stimulation received by the trace(s) to the electrode.
US09409005B2 Apparatus and method for deploying a surgical preparation
A device used for applying an antiseptic preparation to a surgical site of a patient prior to surgery outside of an operating theater. A loose-fitting bag is provided which encloses the surgical site by securing the open end(s) to the patient by closing means. A high friction scrub surface is provided in the bag. A method and apparatus are also provided for releasing antiseptic into the interior of the bag. The method provides that the surgical site can be scrubbed within the bag so as to properly prepare the skin for surgery. A temperature indicator for the antiseptic preparation is also provided.
US09409004B2 Chemically tanning human skin
The invention teaches devices and methods for chemically tanning human skin.
US09408998B2 Reentry catheter and method thereof
The invention generally relates to method and apparatus for crossing an obstruction in a tubular member, and more particularly to a medical device method for crossing of a chronic occlusion in a subintimal or interstitial space of an artery.
US09408993B2 Nitric oxide delivery device
A nitric oxide delivery device including a valve assembly, a control module and a gas delivery mechanism is described. An exemplary gas delivery device includes a valve assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line-of-sight signals to communicate the gas data to a control module. Exemplary gas delivery mechanisms include a ventilator and a breathing circuit. Methods of administering gases containing nitric oxide are also described.
US09408990B2 Oxygen mixing valve
An oxygen mixing valve comprises a valve body. The valve body has an oxygen inlet, an air inlet, and a gas mixture outlet. A mixing chamber in communication with the gas mixture outlet, an oxygen chamber in communication with the oxygen inlet, and an air chamber in communication with the air inlet are disposed in the valve body. A first guide seat is elastically disposed in the oxygen chamber, and a second guide seat is elastically disposed in the air chamber. A first ball and a second ball are respectively disposed at inner ends of the first guide seat and the second guide seat. The first ball and the second ball are connected through a ball mandril. A mandril is movably disposed at an outer end of the first guide seat, a bearing capable of rotating is disposed at an outer side of the mandril, an involute cam is disposed at an outer side of the bearing, and the involute camis connected to an output shaft of a stepper motor. The oxygen mixing valve has advantages of simple structure, convenient mounting and maintenance, low manufacturing cost, capability of sensitively and precisely adjusting the ratio of the oxygen to air, and capability of controlling the tidal volume in conjunction with a common proportional valve.
US09408987B2 Inhaler
An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.
US09408985B2 Drug delivery device
The subject invention provides a drug delivery device for injecting medicament which includes: a tubular reservoir; a stopper slidably disposed in the reservoir; a spring for moving the stopper in the reservoir; at least one needle, the needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, the lumen being in direct or indirect communication with the reservoir; a needle driver for displacing the needle; and, an actuator. Activation of the actuator causes the spring to move the stopper and the needle driver to displace the needle. The needle moves relative to, and separately from, the reservoir with the needle being displaced. Advantageously, with the subject invention, a drug delivery device is provided wherein a needle is moved, relative to the reservoir, in being displaced for injection. This permits control of the needle displacement separate from the reservoir.
US09408984B2 Self-injection device
A self-injection device (101) for delivering a medicament includes a housing (111), and a needle (103) connected to the housing (111). A compressible reservoir (121) is connected to the housing (111) and is in fluid communication with a needle (103) such that compressing the reservoir (121) delivers medicament from the reservoir (121) to the needle (103) and moves the needle (103) from the first position to the second position. A platform (171) is disposed within the housing (111) about which the housing (111) is rotatable between a plurality of positions. Each of the positions corresponds to a different distance the needle (103) is moved to the second position during an injection to provide a variable injection depth. The needle (103) is withdrawn into the housing (111) after an injection without requiring manual manipulation by the user, thereby preventing needle sticks and other accidents.
US09408981B2 Adjustable volume syringe
Adjustable volume syringes and systems are disclosed. An adjustable volume syringe includes a delivery syringe barrel, a reservoir syringe barrel positioned at least partially within the delivery syringe barrel, and a reservoir plunger positioned at least partially within the reservoir syringe barrel. The delivery syringe barrel is configured to contain a first amount of a fluid. The reservoir syringe barrel is configured to contain a second amount of the fluid. A system includes the adjustable volume syringe, a dispensing module in communication with the syringe, and a processor in communication with the dispensing module. The processor may be configured to determine an administration amount of the fluid in the adjustable volume syringe, and transmit signals causing the dispensing module to adjust the volume of fluid in the syringe to the administration amount and deliver the administration amount by moving the reservoir syringe barrel with respect to the delivery syringe barrel.
US09408978B2 Dose setting mechanism for priming a drug delivery device
A method and system for priming a drug delivery device are provided. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.
US09408977B2 Drive mechanism for a drug delivery device and drug delivery device
The drive mechanism comprises a drive member inside a housing, a rotation member and a dose member. The drive member is rotatable with respect to the housing. The rotation member is also rotatable and unidirectionally rotationally engaged with the drive member. The dose member is able to move along a set/deliver path between a first axial position and a second axial position in either direction or to move along a cancel path from the second axial position to the first axial position. An engagement of the dose member with the rotation member causes the rotation member to rotate when the dose member is moved along the set/deliver path. The drive member is not rotated when the dose member is moved along the cancel path. A button in/out spline can be provided for the set/deliver path and a cancel spline for the cancel path.
US09408972B2 Needle-free injection device
A needle-free injection device having an outer housing and an inner housing is disclosed. The inner housing is configured to receive a needle-free syringe in one end. In addition, the inner housing is movable within the outer housing between a syringe loading position and a firing position. The device also includes an activation button operatively associated with the inner and outer housings and a housing lock engaged by the activation button to prohibit movement of the inner housing from the syringe loading position to the firing position when the activation button is activated with the inner housing in the syringe loading position. Methods and apparatus for using, filing and operating the needle-free injection device are also disclosed.
US09408965B2 Method and system for handling and transporting syringes
A method and system for use in the transportation, sterilization and handling of syringe barrels includes a tray having an array of apertures. The tray comprises features for interfacing with other features such as bins whereby the tray is supported generally horizontally and one or more syringes may be lowered into the tray.
US09408964B2 Power injection catheters and method of injecting
Power injection catheters for high flow rate delivery of fluids are disclosed. In one embodiment, a catheter may include a body defining one lumen and a plurality of extension tubes each comprising a lumen in fluid communication with the one lumen of the catheter body. Further, an extension tube may be configured for performing power injection and an extension tube may include a proximal valve. In another embodiment, a catheter may comprise a plurality of lumens and extension tubes, each of the extension tubes comprising a lumen in fluid communication with one lumen of the catheter body, respectively. At least one extension tube may be configured for performing power injection and at least one extension tube may include a proximal valve. Such catheters may include a pressure relief mechanism for preventing overpressurizing of the catheter. A method of injecting a fluid into a patient's body is disclosed.
US09408963B2 Materials delivery system for stapling device
There is disclosed a materials delivery system for use with a surgical stapling instrument having at least one jaw including a knife slot. The materials delivery system includes a series of treatment material receiving pockets positioned adjacent the knife slot such that a portion of each pocket is open to the knife slot. A source of treatment material is positioned within the pockets such that passage of the knife blade adjacent to the pockets repeatedly coats the knife blade with the treatment material.
US09408962B2 Methods for removing cytokines from blood with surface immobilized polysaccharides
The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non microporous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.
US09408960B2 Partial radial heat exchanger and oxygenator
Methods of making a combination heat exchanger and oxygenator. A heat transfer tubing is wound about a core and a potting compound is applied to a portion of the wound tubing. The potting compound solidifies to form a potting structure defining an internal face substantially parallel with a longitudinal axis of the core. The assembly is cut along a line passing through the potting structure to define a core assembly having a cut face substantially parallel with the axis. The cut tubing forms a plurality of capillary tubes, each terminating at opposing, first and second ends, and each extending about the core along an arc angle of less than 360 degrees. An oxygenator bundle is formed as part of the core assembly and includes a plurality of gas exchange fibers. The core assembly is disposed within a housing having a blood inlet and a blood outlet.
US09408959B2 Integrated perfusion device
An integrated perfusion apparatus or device for use in e.g. extracorporeal membrane oxygenation, cardiopulmonary bypass, or isolated organ or limb perfusion, comprises a blood pump for circulating blood through the device; a blood oxygenator for oxygenating blood, and at least one heat control unit capable of controlling and/or regulating blood temperature within the device, wherein the at least one heat control unit comprises at least one solid state heating and/or cooling source, such as at least one Peltier device. The invention also relates to a method of performing perfusion on a patient, limb or organ, comprising using the perfusion device.
US09408957B1 Breast pump shield
Embodiments of a breast pump shield are disclosed herein. According to various embodiments, the breast pump shield can include a body portion that has a breast engagement portion and a throat portion. The breast engagement portion can include a ring. The breast engagement portion can receive at least a portion of a breast of a user, and the throat portion can be configured to receive at least a portion of a nipple of the user and to receive milk from the breast. The breast pump shield also can include a suction chamber located adjacent to the throat portion, and a cover located at the ring of the body portion. The cover can include a support layer and a lubricant layer. The cover can provide at least part of a hermetic seal for the breast pump shield prior to use.
US09408956B2 Cellular control and tissue regeneration systems and methods
A system for in-vivo and ex-vivo tissue regeneration and cellular control, manipulation and management includes a source of cell manipulating factors, which are administered to a therapy zone via active pressure-differential components including a pump and a controller, or pulse-waves generated passively. A plate comprising tissue or an inert, bio-compatible material is provided in the therapy zone in proximity to a fluid flow manifold and tissue scaffolding. A tissue regeneration and cellular control method includes the steps of providing a cell manipulation factor source, providing one or more factors to a therapy zone and forming a pressure wave with a mechanical component or an in-vivo pressure wave source, such as the circulatory or lymphatic system.
US09408953B2 Biodegradable supporting device
A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold.
US09408944B2 Paste-like bone cement
A paste contains at least one monomer for radical polymerization, at least one polymer that is soluble in said at least one monomer for radical polymerization, and at least one filling agent that is poorly soluble or insoluble in said at least one monomer for radical polymerization. The filling agent is a particulate inorganic calcium salt comprising the following properties: at least 90% by weight of the particulate inorganic calcium salt have a particle size of less than 63 μm, as determined by means of sieve analysis; and the solubility in water of the particulate inorganic calcium salt at 20° C. is less than 8.5 g per liter. A kit and the paste is usable for mechanical fixation of articular endoprostheses, for covering skull defects, for filling bone cavities, for femuroplasty, for vertebroplasty, for kyphoplasty, for the manufacture of spacers or for the production of carrier materials for local antibiotics therapy, as well as a form body.
US09408940B2 Odor-controlling bodily fluid absorber
An odor-controlling bodily fluid absorbent member comprises (a) an absorbent material or substrate; and (b) a halo active aromatic sulfonamide compound of Formula (I): wherein R1, R2, R3, R4, R5, X, M, and n are as described herein; and wherein at least one of R1, R2, R3, R4, and R5 is not hydrogen. The absorbent member effectively controls odor arising from various body fluids.
US09408939B2 Anti-microbial air processor for a personal patient warming apparatus
An anti-microbial air processor is configured and arranged to fit at least substantially across an airway in a personal patient-warming apparatus to thereby inactivate airborne microbes before those airborne microbes are exposed to a patient via warming air delivered by the personal patient-warming apparatus. By one approach, the anti-microbial air processor comprises an anti-microbial air filter. By another approach, in lieu of the foregoing or in combination therewith, the anti-microbial air processor comprises one or more ultraviolet light sources configured to expose at least one inner surface of the personal patient-warming apparatus to ultraviolet light to thereby inactivate microbes.
US09408934B2 Compositions and methods for improving toughness of irradiated sterilized bone allografts
The present invention relates to compositions, methods, kits and systems employing irradiation activated agents to improve or increase or prevent loss of toughness, work-to-fracture, post-yield toughness, fracture toughness and/or fatigue strength of a bone allograft on exposure to radiation. The irradiation activated agent can be an agent that increases crosslinking of collagen in bone during irradiation, for example ribose, 2-hydroxytetrahydropyran or ascorbate.
US09408933B2 Antiseptic compositions, methods and systems
Antiseptic compositions comprising at least one salt of EDTA are disclosed. These compositions have broad spectrum antimicrobial and antifungal activity and they also have anticoagulant properties. The antiseptic compositions have also demonstrated activity in penetrating and breaking down microbial slime, or biofilms. They are safe for human and medical uses and may be used as prophylactic preparations to prevent infection, or to reduce the proliferation of and/or eliminate existing or established infections.
US09408931B1 Methods and apparatuses for applying agent to objects
Methods and apparatus for the sanitization, detoxification, disinfection, high level disinfection, or sterilization of both the interior and exterior surfaces of at least one object, including interior lumens, channels and cavities within the object. A coupler and interface may be secured to an object to disinfect the inner channels or cavities therein. An object support device may be used to support the object. The pair of support devices may include outlets for deploying aerosols for the application of applied agent. The applied agent may be in the form of any gas, vapor, plasma, aerosol, or other form. The temperature of the object may be lowered to condensate applied agent thereupon. The object may also be washed. Complete sanitization, disinfection, or sterilization of objects in a simple chamber, or in more complex configurations that include, glove box units, processors with built in interfaces for specialty applications, and other application specific designs.
US09408928B2 Compositions for targeted imaging and therapy
The present invention relates to the field of radiochemistry, nuclear imaging, radionuclide therapy and chemical synthesis. More particularly, it concerns a strategy for radiolabeling target ligands. It further concerns methods of using those radiolabeled ligands for imaging, radionuclide therapy and tissue-specific disease imaging.
US09408927B2 Contrast agents for applications including perfusion imaging
The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-I, and an imaging moiety, and scanning the subject using diagnostic imaging.
US09408926B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
The present invention provides polypeptides, peptide dimers, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 μM), and dimer and multimeric constructs comprising these polypeptides, particularly contrast agents. Also provided are methods for monitoring and evaluating the therapeutic effectiveness of treatment protocols for diseases associated with angiogenesis or endothelial cell hyperproliferation, such as cancer, using contrast agents of the invention.
US09408925B2 Hyperpolarized lactate contrast agent for determination of LDH activity
A hyperpolarized MR imaging medium and a method of 13C-MR detection using a hyperpolarized MR imaging medium for the determination of lactate dehydrogenase (LDH) activity. The contrast media comprises hyperpolarized [13C, 2H] lactate.
US09408924B2 Bioconjugates of cyanine dyes
Compounds are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. Bioconjugate cyanine compounds of Formula II are presented: wherein Q is a portion of a polymethine bridge selected from the group consisting of:
US09408923B2 Hydrophilic self-immolative linkers and conjugates thereof
The present disclosure provides compounds with a hydrophilic self-immolative linker, which is cleavable under appropriate conditions and incorporates a hydrophilic group to provide better solubility of the compound. The compounds of the present disclosure comprise a drug moiety, a targeting moiety capable of targeting a selected cell population, and a linker which contains an acyl unit, an optional spacer unit for providing distance between the drug moiety and the targeting moiety, a peptide linker which can be cleavable under appropriate conditions, a hydrophilic self-immolative linker, and an optional second self-immolative spacer or cyclization self-elimination linker.
US09408911B2 Anticancer prodrugs activated by radiation or ultraviolet treatment and use thereof
The present invention relates to an anticancer prodrug consisting of peptide of acetyl-SEQ ID NO: 1-linker-anticancer drug. The anticancer prodrug effectively provides an anticancer drug unstable in acid and base, such as doxorubicin, in a form of prodrug. Thus, the anticancer prodrug exists as a non-toxic inactive form when administered into the body, but effectively releases the anticancer drug as an active ingredient in the target area in the presence of caspase activated by radiation or UV treatment after administered into the body. Accordingly, the anticancer drug exhibits selective anticancer effects on cancer cells, thereby maximizing the therapeutic effect and minimizing the side-effects of chemotherapy.
US09408909B2 Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination
We provide new methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human DCs and the use thereof in cancer vaccination. The method includes the introduction of different molecular adjuvants to human DCs by contacting or modifying them with mRNA or DNA molecule(s) encoding CD40L, and CD70 or constitutively active TLR4 (caTLR4).
US09408902B2 Synthetic replikin peptides against pathogenic infection of invertebrates in aquaculture
The present invention provides isolated or synthesized peptides of about 7 to about 50 amino acids identified in the genome of pathogens in invertebrates in aquaculture for prevention and treatment of outbreaks of these pathogens in aquaculture and methods of preventing and treating pathogenic outbreaks using the identified peptides.
US09408895B2 Method of treating pregnancy-induced hypertension
A therapeutic agent for the treatment of toxemia, preeclampsia and eclampsia and a method for preparing the therapeutic agent are disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive/pancreatic enzymes. The therapeutic agent may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic agent may be made orally, through injection, by adherence of a medicated patch or by other methods. Further, a method of using the presence of chymotrypsin in the maternal GI tract as a biomarker, to determine the likelihood of developing preeclampsia, a pregnancy induced hypertension, and eclampsia/toxemia is disclosed.
US09408893B2 Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
The present invention refers to a pharmaceutical combination for use in glycemic control in diabetes type 2 patients.
US09408888B2 High affinity bivalent helically constrained peptide against cancer
The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.
US09408882B2 Oral administration of melanin for protection against radiation
Methods and compositions are provided for alleviating and/or preventing one or more side effects associated with exposure to radiation in a subject exposed to radiation or at risk for exposure to radiation comprising oral administration to the subject of an amount of an edible source of melanin effective to alleviate a side effect associated with radiation.
US09408879B2 Bifidobacterium bifidum strains for application in gastrointestinal diseases
The present invention provides a strain of Bifidobacterium bifidum or mutant or variant thereof showing at least an adhesion of about 10 bacterial cells per mm2 of epithelial cell monolayer or having at least an adhesion index of 1.5 and a strain of Bifidobacterium bifidum or mutant or variant thereof being Bifidobacterium bifidum MIMBb75, deposited under deposit No. DSM 24514, or a mutant or variant thereof for use as probiotic, in foodstuff and/or as a medicament. Further provided is a probiotic for mulation, comprising any of the strains, mutants or variants mentioned above, uses of said probiotic formulation, strains, mutants and variants thereof and a method for producing said probiotic formulation.
US09408878B2 Lactococcus lactis strains for use in improving digestive condition
The present invention concerns strains of Lactococcus lactis capable of inhibiting the growth of a pathogenic microorganism and/or improving the intestinal epithelial barrier integrity. These strains are suitable for use in the treatment or prevention of a digestive disorder.
US09408875B2 Compositions for repair of defects in tissues, and methods of making the same
Tissue repair compositions, particularly bone repair compositions, containing (a) bone fragments and (b) homogenized connective tissue, and methods for making the same are provided. Some of the inventive tissue repair compositions contain a radioprotectant. The compositions can be used in the form of an injectable gel, an injectable paste, a paste, a putty, or a rehydratable freeze-dried form. Kits for using such tissue repair compositions are also provided.
US09408870B2 Oral care composition
The present invention relates to an oral care composition and a method of disinfecting the oral cavity. So far synthetic material (e.g. Triclosan) has been used which is believed by many consumers to be harsh on them. Consumers, more and more prefer using products that contain natural materials. Further, in many countries, culturally or otherwise, people are reluctant to using alcohol in their mouthwashes. The present inventors have been working on solving these problems and have come up with an oral care composition which includes natural materials that are found to interact synergistically with certain metal salts in killing S. mutans, a bacterium responsible for tooth decay.
US09408868B2 Skin external composition comprising a combination of sodium chloride and glucose as active ingredients for treating vaginosis and the use thereof
The present invention relates to a skin external composition comprising a combination of salt and sugar as an active ingredient in an amount effective to treat and prevent vaginosis, together with a pharmaceutically acceptable carrier, and the use thereof.
US09408867B2 Antifungal compositions for the treatment of skin and nails
The invention concerns a composition and method for treating an ungual infection, the composition comprising an iodophor and dimethylsulfoxide (DMSO).
US09408866B2 Method for detoxification or measurement of at least one compound or at least one fluid in a host body
The present invention comprises a method for detoxification or measurement of the concentration of at least one compound in a host body, wherein said host body comprises a sorption material of at least one phase over a certain period of time, where sorption of said at least one compound in at least one phase of said sorption material is effected and the content of the at least one compound in said sorption material is optionally analyzed. Use of a sorption material for providing an estimate of the concentration of compounds present in a host body, use of a sorption material for detoxification and sorption material for diagnostic use is also comprised in the present application.
US09408864B2 Composition for regenerating normal tissue from fibrotic tissue
The present invention relates to a pharmaceutical composition and a method for regenerating normal tissue from fibrotic tissue, the pharmaceutical composition and the method employing a collagen-reducing substance. In accordance with the present invention, normal tissue can be therapeutically regenerated from fibrotic tissue.
US09408863B2 5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
The present invention relates to 5′-Substituted Nucleoside Analogs of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, Z, R1, R2, R3 and R3′ are as defined herein. The present invention also relates to compositions comprising at least one 5′-Substituted Nucleoside Analog, and methods of using the 5′-Substituted Nucleoside Analogs for treating or preventing HCV infection in a patient.
US09408859B2 Pharmaceutical compositions useful for preventing and treating cancer
Disclosed is a method of treating a cancer on a mammal, comprising administering to the mammal in need thereof a therapeutically effective amount of a compound
US09408853B2 Iridium/rhodium anti-cancer compounds
The present invention relates to novel iridium and/or rhodium containing complexes for use as a cytotoxic, such as an anti-cancer agent. There is also provided a method of preparing said compounds.
US09408851B2 Compounds
Compounds of formula (I) wherein R1 is 2-indanyl, R2 is 1-methylpropyl, R3 is a group selected from 2,6-dimethyl-3-pyridyl or 4,6-dimethyl-3-pyridyl, R4 represents methyl and R5 represents hydrogen or methyl or, R4 and R5 together with the nitrogen atom to which they are attached represent morpholino and pharmaceutically acceptable derivatives thereof are described, as are processes for their preparation, pharmaceutical compositions containing them and their use in medicine, particularly their use as oxytocin antagonists.
US09408849B2 Crystal entecavir, crystal entecavir formulation and methods for the preparation thereof
The present invention relates to a pharmaceutical composition for treating hepatitis B virus infection comprising crystalline entecavir as the pharmaceutically active ingredient and one or more pharmaceutically acceptable excipients. The tablet and capsule of the pharmaceutical composition have improved stability compared to that of amorphous entecavir under the conditions of light, high temperature and high humidity.
US09408836B2 Pharmaceutical composition containing pirfenidone in sustained-release tablet form
The instant invention relates to a process for the preparation of a pharmaceutical composition in sustained-release tablet form comprising from 600 milligrams to 2400 milligrams of Pirfenidone (PFD), in such a way that the drug is bioavailable during an extended period of time of 12 hours from its administration. In this way, the anti-fibrotic and anti-inflammatory action of the drug Pirfenidone is optimized. Moreover, the instant invention offers advantages and a higher therapeutic efficacy compared to other pharmaceutical forms of Pirfenidone for oral administration and its therapeutic application in the regression of chronic renal failure secondary to primary glomerulosclerosis; it shows a better activity with regard to the reduction and/or regression of deleterious effects in breast capsular contracture observed after the surgical implantation of breast implants in humans and has an important anti-TNF-α and anti-TGF-β1 action for the treatment of hepatic fibrosis.
US09408835B2 Pharmaceutical composition for oral administration
A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.
US09408830B2 Phosphodiesesterase 4 inhibitors for the treatment of a cognitive deficit
The present invention provides methods of treating cognitive deficits associated with mental retardation. The methods comprise combining cognitive training protocols and a general administration of phosphodiesterase 4 inhibitors.
US09408829B2 Inhibitors of CD40-TRAF6 interaction
The present invention relates to compounds acting as selective inhibitors of CD40-TRAF6 interaction, their use as medicaments and their use in the treatment of (chronic) inflammatory diseases. The present invention also relates to pharmaceutical compositions comprising these compounds.
US09408828B2 (+)-3′-angeloyloxy-4′-keto-3′,4′-dihydroseselin for treating inflammation
The present invention provides a compound, namely (+)-3′-Angeloyloxy-4′-keto-3′,4′-dihydroseselin (Pd-Ib) derived from Bupleurum malconense as the potential anti-inflammation drug. The present invention also relates to methods of preparing the compounds and using the same for treating inflammation.
US09408823B2 Benzonatate modified release solid tablets and capsules
A 12-hour anti-tussive modified release solid tablet or capsule is described which comprises a benzonatate adsorbate in a matrix with a sufficient amount of one or more pharmaceutically acceptable modified release pH-independent, substances to provide a 12-hour modified release profile to the benzonatate, wherein there is substantially no benzonatate release from the tablet or capsule in the buccal cavity and no more than about 25% release of the benzonatate within 1 hour as determined in an in vitro dissolution assay.
US09408821B2 Methods for the treatment and prevention of age-related retinal dysfunction
A method of treating or preventing age-related retinal dysfunction involves administering to a patient a pharmaceutically effective amount of a synthetic retinal derivative repeatedly over a duration of at least about 3 months. Effective synthetic retinal derivatives include 9-cis-retinyl esters, 11-cis-retinyl esters, derivatives and congeners thereof, and combinations thereof. Suitable ester substituents include carboxylates of C1-C10 monocarboxylic acids and C2-C22 polycarboxylic acids.
US09408819B2 Method for reducing or preventing systemic inflammation
The present disclosure is directed to a novel nutritional formula for treating or preventing systemic inflammation in a subject. The nutritional formula comprises a therapeutically effective amount of inactivated Lactobacillus rhamnosus GG (LGG).
US09408816B2 Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
Provided herein are methods for using at least one histone deacetylase inhibitor to decrease cellular DNA repair activity, methods for monitoring the decrease of cellular DNA repair activity using at least one biomarker, methods of treating cancer by using at least one histone deacetylase inhibitor to decrease cellular DNA repair activity in combination therapy, methods of combination therapy where at least one histone deacetylase inhibitor interferes with a DNA repairing mechanism involving RAD51, methods for predicting a induction time period between a first administration of at least one histone deacetylase inhibitor and a second administration of at least one other therapeutic treatment, and pharmaceutical compositions for combination therapy.
US09408815B2 Bupropion as a modulator of drug activity
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
US09408809B2 Method for preventing the crystallization of pharmaceuticals in a polymer film
The invention relates to a method for preventing the crystallization of a pharmaceutical in a polymer film, wherein the solvent-containing coating compound, which comprises a matrix-forming polymer or polymer mixture and at least one pharmaceutical and is spread to produce the polymer film, is temporarily dried at temperatures that is at least 10° C. above the melting temperature of the pharmaceutical contained in the coating compound. The maximum temperature is thus higher than that which is required for mere drying and obviates the need for an additional, time-consuming and expensive work step.
US09408807B2 Semi-permeable encapsulation system with tapered conduits for diabetes reversal
Some embodiments of the present disclosure include an encapsulated islet for treating diabetes. The encapsulated islet may include a semi-permeable capsular membrane having a plurality of layers including an outer immunoprotection layer, a bridging layer, and an inner backbone layer. A continuous fluid-flow manufacturing process may start production of all membrane layers simultaneously, but at different growth rates for different layers. Each layer may have a plurality of pores, wherein the pores increase in size from the immunoprotection layer to the backbone layer, creating the tapered conduits. The semi-permeable capsular membrane may include the following layers, in order from outermost layer to innermost layer: an immunoprotection layer, a bridging layer, and a backbone layer. With proper balancing of membrane thickness and tapered pore size distribution, the encapsulated islets may be configured to offer a improve insulin transport and offer diabetes patients a treatment or functional cure without immunosuppressive drugs.
US09408799B2 Aerosol antiperspirants
An aerosol antiperspirant composition comprising: at least one active antiperspirant ingredient, a bis-vinyl dimethicone/dimethicone copolymer, a silicone solvent, at least one fatty acid ester and at least one propellant.
US09408797B2 Dermal filler compositions for fine line treatment
The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.
US09408796B2 Cosmetic compositions for improving the appearance of skin
The present invention describes methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of aging, by topically applying compositions comprising aryl-thiazole compounds.
US09408792B2 Isochrysis sp tahitian clone and uses therefore
A novel microalgal strain whose lipid production has been enhanced compared to the wild type. The lipid content produced by the microalgae is particularly rich in neutral lipids. The use of the microalgal strain and the lipids are also described.
US09408779B2 Bottle and cup holder
A bottle and cup holder for retaining a bottle or cup, having a skin cover forming an outermost layer of the holder; a foam insert within the skin cover having a central cavity and an opening. The central cavity has a first section, a second section, and a shoulder. The second section is between the first section and the opening. The shoulder is between the first section and the second section. The second section has a larger diameter than the first section. The bottle and cup holder also has a shoulder bushing within the opening and extending into the central cavity to receive the bottle or cup.
US09408773B2 Compression vest for patients undergoing hemodialysis and in critical care
A method of inhibiting hypotensive symptoms in a patient undergoing treatment or a procedure involves elastically constraining the internal organs within the abdomen of the patient while applying non-pulsating, compressive pressure to the internal organs within the abdomen of the patient. The method may also involve one or more of infusing fluid, applying the compressive pressure using compression device, or applying the compressive pressure based upon bio-indicator measurement parameters.
US09408770B2 Knee rehabilitation device with measurement element
In one example, a rehabilitation device includes a first element having first and second spaced-apart, generally parallel elongate members having proximal and distal ends. A second element is rotatably coupled to the first element and includes first and second spaced-apart, generally parallel elongate members having proximal and distal ends. One of the first and second elements is angularly adjustable relative to the other. A measurement device includes a measurement element connected to one of the first and second elements and configured for rotation relative to one of the first and second elements, such that when the rehabilitation device is operably disposed with respect to a joint of a patient, the measurement element is arranged for contact with anatomy of the patient. Finally, a scale is disposed proximate the measurement element and indicates a position of the measurement element relative to another portion of the rehabilitation device.
US09408764B2 Furniture member and power lift mechanism
A lift chair includes a frame assembly including a chair portion rotatable with respect to a base portion. A lift mechanism portion is positioned in a base portion cavity. The lift mechanism portion includes a lift motor and a drive assembly connected to the lift motor having a slide. A lift tube connects the slide to the chair portion. The lift tube upon actuation of the lift motor displaces the chair portion between a nominal and a full lift position by slide displacement in a slide lifting direction. First and second guide members are positioned on opposite sides of the drive assembly and connected to a base portion base platform. The lift tube is connected to both the first and second guide members to distribute a weight load from the chair portion via the lift tube to the slide, and by the guide members to the base platform.
US09408757B2 Tool for analysing liquid discharge data in an absorbent article, an absorbent article adapted for liquid discharge data collection and a control unit interacting with the absorbent article for collecting the liquid discharge data
An absorbent article for absorbing liquid discharge when worn on the crotch region of the body of a user includes a plurality of detection zones for detecting the liquid discharge. Each detection zone is provided by first and second electrically conductive paths that are electrically isolated from one another and arranged so that a liquid discharge between the first and second conductive paths allows electrical current to flow between the first and second conductive paths which is able to be detected to detect the presence of liquid discharge in the respective zone. The plurality of zones are longitudinally distributed with respect to the absorbent article along an absorbent core of the absorbent article, to allow the longitudinal extent of the discharge to be ascertained. The first and second conductive paths are longitudinally spaced from one another. The first and second conductive paths are elongate and are laterally aligned.
US09408755B2 Wound drainage dressing
The invention relates to a wound drainage covering for covering, by means of low pressure, a wound that is to be treated. The covering comprises at least two layers that are superimposed. A first layer that is applied on the side of the wound is made of a functional textile material and second layer that is arranged thereon is dimensionally stable and permeable to liquid. The wound drainage covering has a simple design and due to the functional first layer, is effective and ensures, due to the dimensionally stable second layer, an optimal removal of wound secretion.
US09408751B2 Multi-lumen connector
Apparatus is disclosed for applying negative pressure to a wound site to promote healing. The apparatus includes a porous pad for application to the wound, a suction tube linking the porous pad to a source of negative pressure, a container for collecting fluid exudate from the wound interposed between the porous pad and the source of negative pressure and a quick disconnect connector linking a first section of the suction tube leading to the porous pad with a second section leading to the container, said connector comprising two separable and non-interchangeable parts, said first section of the suction tube comprising a multi-lumen tube, one lumen being provided for applying suction to the porous pad and another being provided for monitoring pressure, said multi-lumen tube being fixedly attached at one end to the container and at the other end to one of said separable parts, said one separable part including sealing means whereby the lumens are connected in air-tight manner to said second section of the suction tube.
US09408750B2 Reduced-pressure treatment systems and methods employing debridement mechanisms
Reduced-pressure treatment systems and methods are disclosed that employ debridement mechanisms to remove unwanted tissue. In one instance, a reduced-pressure treatment system for treating a tissue site on a patient includes a manifold member for distributing reduced pressure to the tissue site, a support member for disposing proximate the tissue site and the manifold, and a debridement mechanism coupled to the support member. The debridement mechanism is for debriding the tissue site. The system further includes a sealing drape for placing over the tissue site and manifold member. The sealing drape is operable to form a fluid seal over the tissue site and manifold member. The system also includes a reduced-pressure subsystem for delivering a reduced pressure to the sealing drape. The system may further include a chemical-debridement subsystem. Other systems, manifolds, and methods are disclosed.
US09408744B2 Therapeutic device and method
A therapeutic device for relieving an affected organ or part of the body comprises a mass of material such as beeswax which in use is capable of maintaining a temperature range of 36 to 38 degrees Celsius at the affected part of the body when retained on the skin near the affected part. The invention also extends to articles of apparel containing such a therapeutic device.
US09408741B2 Method and apparatus for retention of adipose tissue
A tissue retention system to assist in maintaining adipose tissue on a patient in a displaced position during a medical procedure to provide access to a body region of the patient includes a flexible anchor pad having a pad length and a pad width. The anchor pad may include a pad body with an adhesive surface thereon, the adhesive being configured to selectively adhere to a patient's skin. The anchor pad also may include an opposing first attachment surface facing away from the adhesive surface. The tissue retention system also may include a flexible tension member having a second attachment surface.
US09408735B2 Methods of implanting a prosthesis and treating an aneurysm
A method of implanting a prosthesis in a patient at a treatment site includes advancing an outer catheter of a prosthesis delivery system in the patient distal to the treatment site. An inner sheath and a curved guidewire lumen of the delivery system are advanced from the outer catheter to the treatment site along a guidewire while the outer catheter remains stationary relative to the patient. Advancing the inner sheath causes rotation of the prosthesis to thereby rotationally align the prosthesis at the treatment site. The inner sheath is retracted to deploy a prosthesis from within the inner sheath and at the treatment site. The delivery system is then retracted from the patient.
US09408726B2 System and method for sealing prosthetic socket
Various embodiments of a system and method for sealing a prosthetic socket are disclosed. One example socket sealing system may comprise: a prosthetic socket having a proximal end, an expanded section, and an internal peripheral shoulder; a brim seal having an inner proximal end, an outer proximal end, and a distal end; a removable brim having a distal end; a liner; and a wicking sock; wherein prosthetic socket may be oriented radially outwardly of the outer proximal end of the brim seal, the outer proximal end of the brim seal may be oriented radially outwardly of the removable brim, the removable brim may be oriented radially outwardly of the inner proximal end of the brim seal, the inner proximal end of the brim seal may be oriented radially outwardly of the wicking sock, and the wicking sock may be oriented radially outwardly of the liner; and wherein the brim seal may be reflected about the distal end of the removable brim.
US09408723B2 Connection device
The invention relates to a connection device for connecting an implant system anchored in bone with an external prosthesis component, such as a limb prosthesis, prosthetic knee elbow or finger. The connection device includes a main housing, a first attachment portion arranged for attachment to the implant system and a second attachment portion arranged for attachment to the prosthesis component. It further includes a safety mechanism to protect the implant system from high mechanical forces, including rotational forces and or bending forces. According to one aspect of the invention the safety mechanism includes a rotational force release mechanism. This includes a first component including a ring unit having an inner surface with at least one depression and a second component includes at least one plunge unit urged into contact with said the depression by said spring means. According to another aspect the safety mechanism includes a bending force release mechanism with the second attachment portion being pivotable and having a spring loaded cam unit acting on a cam surface of the main hosing. According to a further aspect the safety mechanism is arranged to limit rotating forces as well as bending forces.
US09408716B1 Percutaneous posterior spinal fusion implant construction and method
A system includes tubular members removably positionable over a passageway device connected to a connecting element attached to a vertebra. The tubular members may each include a sidewall having an opening positionable adjacent a proximal end of the passageway device when the tubular member is positioned over the passageway device. The tubular members include channels therein to receive respective blades of the passageway devices. One of the tubular members may be a counter torque tube, and another two of the tubular members may be a hinge shaft and a ball shaft, respectively, of a compression and distraction system. The blades of each passageway device may be integrally formed with a cage of the connecting element to form a monolithic blade-screw. The blades of the monolithic blade-screw may be constructed by affixing distal ends of non-threaded blade extensions to proximal ends of threaded reduction portions integrally connected to the cage.
US09408713B2 Flexible vertebral spacer
A flexible implant system for positioning a flexible spacer between adjacent vertebrae including and interbody spacer and an insertion instrument. The interbody spacer including a central axis, a lateral axis, a top surface positioned generally parallel to the central axis and a plurality of hinge sections extending generally perpendicular to the central axis. A plurality of notches making up the plurality of hinge sections adjacent the top surface that permit the interbody spacer to flex. The interbody spacer further including a groove extending along a lateral side surface, generally parallel to the central axis. An insertion instrument includes a proximal end, a distal end and a tongue extending from the proximal end to the distal end along a non-linear path. The groove slidably engages the tongue to guide the interbody spacer from the proximal end to the distal end along the non-linear path.
US09408710B2 Intervertebral device and methods of use
An intervertebral device comprises a plurality of struts that are rotatably associated with each adjacent strut to form a modifiable inner volume V for bone graft containment.