Document Document Title
US08420984B2 Household appliance
The present invention relates to a household appliance for performing a housekeeping task. The household appliance comprises a data input device (16) adapted to remotely sense a property in a sensing area (18), and a controller (22) coupled to the data input device and adapted to control an operation of the household appliance in accordance with the sensed property.
US08420983B2 Vapor cooker
A steam cooker 1 has: a steam generation heater 52 generating steam; and a steam heating heater 41 heating the steam generated by the steam generation heater 52 to generate overheated steam and heating steam in a heating chamber 20 through circulation, an-article-to-be-heated F being cooked by use of steam fed into the heating chamber 20. The steam cooker 1 has: a first cooking step in which the article-to-be-heated F is cooked with supply of electric power to the steam generation heater 52 being larger than that to the steam heating heater 41; and a second cooking step in which the article-to-be-heated F is cooked with supply of electric power to the steam generation heater 52 being smaller than that to the steam heating heater 41. When the temperature of the article-to-be-heated F exceeds the fat melting temperature zone but is less than or equal to 100° C., the first cooking step is switched to the second cooking step.
US08420981B2 Apparatus for thermal processing with micro-environment
A substrate thermal processing system. The system has at least one substrate holding module having a housing configured for holding an isolated environment therein. A substrate heater is located in the housing and has a substrate heating surface. A substrate cooler is located in the housing and having a substrate cooling surface. A gas feed opening into the housing and feeding inert or reducing gas into the housing when the substrate is heated by the heating surface. A gas restrictor is within the housing restricting the fed gas between the substrate heating surface and a surrounding atmospheric region substantially surrounding the substrate heating surface in the housing and forming an aperture through which the fed gas communicates with the atmospheric region.
US08420979B2 Method and apparatus for laser beam processing of an element with total transmission for light of a t least 10-5
A method and an apparatus for laser beam processing of an element (12) that has a total transmittance for light of at least 10−5, comprising a laser unit (1) for generating a laser beam on one side of the to-be-processed element (12), an illumination unit (7), an imaging system (10) comprising a sensor unit on the one side of the to-be-processed element (12), the sensor unit recording residual light that results from light of the illumination unit (7), a scanning unit (2) for adjusting the laser beam processing position, and a control unit. The control unit is operatively connected to the laser unit (1), the imaging system (10) and the scanning unit (2), and the illumination unit (7) is positioned on the other side of the to-be-processed element (12) in relation to the laser unit (1). Since the to-be-processed element (12) allows light to pass through an otherwise opaque or almost opaque layer, a good contrast is obtained that is used to determine the position of the laser beam with high precision.Therefore, high precision laser processing is possible for materials with low transmission for light and low mechanical stability like flexible thin film solar cells.
US08420975B2 Plasma torch, plasma torch nozzle, and plasma-working machine
A plasma torch includes a torch main unit and a nozzle. The torch main unit has a nozzle seat member on which the nozzle is mounted. The nozzle is arranged to move toward or away from the nozzle seat member in a direction substantially parallel to a center axis of the nozzle when the nozzle is mounted on or removed from the nozzle seat member. The nozzle has an electroconductive surface facing the nozzle seat member. The torch main unit has an elastic electric contact portion contacting with the electroconductive surface of the nozzle to form an electroconductive path for a pilot arc to the nozzle. The electroconductive surface of the nozzle presses the electric contact portion in the direction substantially parallel to the center axis when the nozzle is moved toward the nozzle seat member to mount the nozzle on the nozzle seat member.
US08420971B2 Switching chamber insulation arrangement for a circuit breaker
A switching chamber insulation arrangement and a circuit breaker having such a switching chamber insulation arrangement are provided. The switching chamber insulation arrangement provides improved heat dissipation in the area of the contact areas of switch contact poles. The switching chamber insulation arrangement includes a strut arrangement having a plurality of struts. Each strut has a first foot area, a second foot, area and a center area which is located between the first foot area and the second foot area, respectively. The struts are arranged along a circumference around a longitudinal extent axis of the strut arrangement. The strut arrangement has a first mechanical coupling area on a side of the first foot areas for coupling to a first pole of a circuit breaker, and a second mechanical coupling area on a side of the second foot areas for coupling to a second pole of a circuit breaker.
US08420965B2 Button assembly with drive assembly
A process is provided for characterizing a tactile response of a first mechanical actuator (e.g., button) based on a back off distance. The first mechanical actuator may include a plunger, a dome-shaped flexible membrane, and an electrical contact, all aligned with each other so that a contact signal is generated when the flexible membrane touches the contact. The plunger can be moved a first distance towards the contact until the contact signal is generated at a contact point. Then the plunger can be backed off a second distance from the contact point. This second distance may be called the “back off distance”. The particular feel of the first mechanical actuator can then be correlated to a particular back off distance. This process can be repeated a number of times to classify a number of different “feels” for the first mechanical actuator based on a number of different back off distances.
US08420959B2 Manual drive
The invention relates to a manual drive for step-by-step operation, without any power, of a tap changer (1) on a tap-changing transformer. The manual drive has a position indication wheel (4) which is used not only, in conjunction with a pointer (15), for actual position indication, but at the same time as a component of mechanical final-position limiting (10, 11, 12). It can also furthermore be used (18) in a particularly advantageous manner as a component of electrical switching monitoring.
US08420958B2 Position apparatus for touch device and position method thereof
A position apparatus of a touch device and a position method thereof are provided, wherein the touch device includes a plurality of scan lines. In the position method, a plurality of capacitances in the scan lines are sensed. Next, a plurality of capacitances respectively sensed in an ith scan line of the scan lines and a subset of the scan lines neighboring with the ith scan line are selected. When the capacitance sensed in the ith scan line is larger than each of the capacitances sensed in the subset of the scan lines, the capacitance sensed in the ith scan line is determined as a peak capacitance. Finally, a touch position is calculated according to the peak capacitance and the capacitances sensed in the subset of the scan lines.
US08420957B2 Method for weighing laundry by measuring energy used by a drum motor at different angular speeds
A method for weighing laundry inside a washing machine comprises a first step of optimization of the distribution of the laundry in the basket, a second step of definition of a flywheel of laundry with a constant moment of inertia, and a third step of measurement of the energy absorbed by the motor drive for moving the basket during a predefined angular acceleration of the loaded basket.
US08420954B2 Printed circuit board and method for fabricating the same
The invention provides a printed circuit board and a method for fabricating the same. The printed circuit board includes a core substrate having a first surface and an opposite second surface. A first through hole and a second through hole are formed through a portion of the core substrate, respectively from the first surface and second surfaces, wherein the first and second through holes are laminated vertically and connect to each other. A first guide rail and a second guide rail are, respectively, formed through a portion of the core substrate and connected to the second through hole, so that a fluid flows sequentially from an outside of the printed circuit board through the first guide rail, the second through hole and the second guide rail, to the outside of the printed circuit board.
US08420953B2 Dummy memory card
A dummy memory card includes a circuit board and a golden finger board. The circuit board includes a first conductive element and a second conductive element connected to a first electrical load. The golden finger board extends from the circuit board and is inserted into a memory slot of a motherboard. The golden finger board includes a first power pin and a first ground pin. The first conductive element is electrically connected to the first power pin. The second conductive element is electrically connected to the second power pin.
US08420944B2 Connection structure of flexible printed circuits and optical pickup device including the connection structure
A connection structure of Flexible printed circuits comprising: first and second Flexible printed circuits, respectively, including a base formed of a resin, a plurality of wiring patterns arranged side by side on the base, a cover film formed of a resin to cover opposite sides of the wiring patterns to the base, and a connection portion in which the plurality of wiring patterns are not covered by the cover film, the connection portions of the first and second Flexible printed circuits being connected with each other. The wiring patterns in the connection portions include a large width portion which is larger in width than the wiring patterns covered by the cover film. The large width portions on the first Flexible printed circuit and the large width portions on the second Flexible printed circuit are connected to each other by means of soldering.
US08420943B1 Wiring grommet with body contact portion
Disclosed herein are embodiments of an electrical wiring grommet. In one aspect, an electrical wiring grommet includes a body mounting portion, a closure panel mounting portion and a flexible conduit portion extending between the body mounting portion and the closure panel mounting portion. The flexible conduit portion includes a longitudinally extending body contact segment having a circumference, the circumference having a first circumferential portion and a second circumferential portion. The first circumferential portion includes a corrugated surface having a plurality of ridges with a first ridge height, and the second circumferential portion includes a corrugated surface having a plurality of ridges with a second ridge height less than the first ridge height.
US08420939B2 Flame retardant, low smoke emission, halogen free 600 V energy cable with polyolefin insulation and polyamide jacket
Flame retardant, low smoke emission and halogen free energy cable with silane cross-linked polyolefin insulation and polyamide jacket for electrical installations up to 600 V, based on: a) an electric conductor core made of copper or aluminum; b) an insulating layer made of silane cross-linked polyethylene; and c) a flame retardant nylon-6 jacket with low smoke emission; characterized in that said core a) is based on a plurality of soft copper wires with electrical resistivity no greater than 17,241 nOhm.m (0.15328 Ohm.g/m2) equivalent to a IACS 100% conductivity or aluminum with electrical resistivity not greater than 28,264 nOhm.m (0.07639 Ohm.g/m2) equivalent to a IACS 61% conductivity and having reduced insulating thicknesses.
US08420936B2 Cable harness
A cable harness has a wire group made of plural electric wires, connector terminals provided at both ends of the wire group, a braid sleeve provided around an outer periphery of the wire group, and ground connecting parts provided at both ends of the braid sleeve that are configured to be electrically connected to a ground part in an equipment. The braid sleeve includes a metallized high tension fiber.
US08420934B2 Crossing bus support apparatus, connectors, systems, and assemblies and methods of installing same
Embodiments provide a crossing bus support apparatus and connectors thereof. The crossing bus support apparatus includes a body structure having a first portion with a plurality of phase bus slots, the phase bus slots adapted to receive a plurality of crossing buses, a first connector on a first end having dual protrusions each protrusion having an interlockable feature; and a second connector on a second end having dual protrusions each protrusion having an interlockable feature. The crossing bus support apparatus may be used in pairs to capture crossing buses into the phase bus slots. Systems, assemblies, connectors, and methods of installing and utilizing the crossing bus support apparatus are provided, as are other aspects.
US08420933B2 High-pressure-resistant hermetic seal terminal and method of manufacturing the same
A high-pressure-resistant hermetic seal terminal includes an eyelet which has a through hole and a lead which is electrically insulated and hermetically sealed via a glass material in the through hole. The glass material is welded in a manner to extend on a lower surface of the eyelet from an end of the through hole to surroundings of the end of the through hole. Preferably, the eyelet has a counterbore, in the lower surface, extending in a region around and surrounding the through hole, and the glass material is welded to the inside of the counterbore.
US08420929B2 Electrical ground fault protection device
A ground fault protection device includes an electrically-conductive main body defining a reservoir having a plurality of drainage ports, and having downwardly-extending, ground-penetrating electrodes configured for minimal ground penetration. The device has handles for manual lifting and transportation, plus grounding terminals for connection of grounding cables. The device may be installed at a desired field location by applying downward force to the device to press the electrodes into the earth, thereby establishing an electrical connection between the grounding terminals and the ground via the main body and the electrodes. Grounding cables may then be connected between the grounding terminals and structures or equipment requiring grounding. Optionally, the reservoir may be filled with water, which will drip through the drainage ports and moisten the soil surrounding the electrodes, thereby decreasing the soil's electrical resistance and consequently improving electrical conductivity between the electrodes and the soil.
US08420928B2 Use of photovoltaics for waste heat recovery
A device for recovering waste heat in the form of radiated light, e.g. red visible light and/or infrared light includes a housing having a viewing window, and a photovoltaic cell mounted in the housing in a relationship to the viewing window, wherein rays of radiated light pass through the viewing window and impinge on surface of the photovoltaic cell. The housing and/or the cell are cooled so that the device can be used with a furnace for an industrial process, e.g. mounting the device with a view of the interior of the heating chamber of a glass making furnace. In this manner, the rays of the radiated light generated during the melting of glass batch materials in the heating chamber pass through the viewing window and impinge on the surface of the photovoltaic cells to generate electric current which is passed onto an electric load.
US08420927B2 Solar cell, method of manufacturing the same, and solar cell module
A solar cell and a solar cell module including the solar cells are disclosed. The solar cell includes a substrate of a first conductive type; an emitter layer of a second conductive type positioned at a light receiving surface of the substrate; a plurality of first electrodes that are positioned on the emitter layer and are electrically connected to the emitter layer; and at least one first current collector that is positioned on the emitter layer in a direction crossing the plurality of first electrodes, wherein a thickness of each of the plurality of first electrodes is different from a thickness of the at least one first current collector, and a difference of the thickness of the each first electrode to the thickness of the at least one current collector is equal to or less than about 0.5 times the thickness of the at least one first current collector.
US08420926B1 Hybrid solar cell integrating photovoltaic and thermoelectric cell elements for high efficiency and longevity
Methods, systems and apparatus for a solar cell integrating photovoltaic and thermoelectric cell elements to form a hybrid solar cell. The cell has increased efficiency and longevity by combining operations of the photovoltaic and thermoelectric elements in at least three different modes of operation to increase electrical output per unit of panel area and to increase cell life, improve performance, and provide operational benefits under different environmental conditions.
US08420925B2 Solar energy device for electricity and heating
A solar energy collector produces electricity and heat using an optically transparent vessel containing one or more photovoltaic cells and a liquid that substantially fills the vessel. The vessel has a top with a flat exterior surface and a bottom with a concave exterior surface that is coated on the outside with a reflective material. Solar radiation traveling through the top of the vessel into the liquid and through the bottom strikes the reflective material on the outside of the vessel and is reflected back through the bottom, into the liquid and to a focal line adjacent to the interior surface of the top. Cooled liquid is fed into the vessel through an entry port and heated liquid is removed through an exit port. One or more photovoltaic solar cells are located adjacent to the interior surface of the top aligned with the focal line.
US08420923B1 Music playing device for symphonic compositions
A music playing device for symphonic compositions allows a user to selective locate one or more musical instrument playing pieces within an orchestral pit and to listen to the series of notes of those instruments placed into the pit. The additive and subtractive benefits of musical instruments are thus appreciated. The device comprises a main base and individual, preferably, three dimensional musical instruments as playing pieces. Multiple symphonic musical compositions are available to be played with only the notes of those instruments being heard if and when placed into the pit area.
US08420916B1 Maize variety inbred PH13BK
A novel maize variety designated PH13BK and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH13BK with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH13BK through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH13BK or a locus conversion of PH13BK with another maize variety.
US08420911B1 Maize variety inbred PH133Z
A novel maize variety designated PH133Z and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH133Z with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH133Z through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH133Z or a locus conversion of PH133Z with another maize variety.
US08420908B2 Plants and seeds of hybrid corn variety CH594494
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH594494. The invention thus relates to the plants, seeds and tissue cultures of the variety CH594494, and to methods for producing a corn plant produced by crossing a corn plant of variety CH594494 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH594494.
US08420907B1 Inbred corn line NPFA5849
Basically, this invention provides for an inbred corn line designated NPFA5849, methods for producing a corn plant by crossing plants of the inbred line NPFA5849, with plants of another corn plant. The invention relates to the various parts of inbred NPFA5849, including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPFA5849, and plants produced by said methods.
US08420905B2 Pepper hybrid BS02827975
The invention provides seed and plants of pepper hybrid BS02827975 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid BS02827975 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08420900B2 Soybean variety A1024077
The invention relates to the soybean variety designated A1024077. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024077. Also provided by the invention are tissue cultures of the soybean variety A1024077 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024077 with itself or another soybean variety and plants produced by such methods.
US08420895B2 Soybean cultivar S080137
The invention relates to the seeds of soybean cultivar S080137, to the plants of soybean S080137, to plant parts of soybean cultivar S080137, and to methods for producing a soybean plant produced by crossing soybean cultivar S080137 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080137, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080137, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080137 with another soybean cultivar.
US08420892B2 Delta-9 elongases and their use in making polyunsaturated fatty acids
Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding delta-9 elongases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these delta-9 elongases in plants.
US08420889B2 Epicatechin glucosyltransferase
The invention provides methods and compositions for the modulation of epicatechin glucosyltransferase activity in plants. Increased expression of epicatechin glucosides, and ultimately anthocyanins and proanthocyanidins, in plants may be used to increase the nutritional value of food plants for both human and animal consumption. Increased proanthocyanidin content also reduces the potential for bloat in animals fed certain forage plants low in condensed tannin content.
US08420882B2 Wound and therapy compress and dressing
A method of providing moisture therapy to a subject by applying a moist therapy compress against a treated body portion. The moist therapy compress includes a fluid-permeable shell, a flexible backing fastened to the shell to define an enclosure, and a hydrophilic zeolite fill granules loosely contained within the enclosure. The therapy compress is exposed to a source of moisture to cause absorption of water into the a hydrophilic zeolite, and the moisture is delivered from the hydrophilic zeolite through the fluid permeable shell to the treated body portion.
US08420881B2 Process for the destruction of sulfur and nitrogen mustards, lewisite, and their homologous/analogues in deep eutectic solvents
The subject invention provides a potentially economically viable process for the destruction of small to large quantities of sulfur and nitrogen mustards and lewisite, their homologous/analogues, and similar chemical warfare agents at ambient conditions without producing any toxic by-products. The process uses the superoxide ion that is either electrochemically generated by the reduction of oxygen in deep eutectic solvents or chemically by dissolving Group 1 (alkali metals) or Group 2 (alkaline earth metals) superoxides, e.g. potassium superoxide, in deep eutectic solvents.
US08420879B2 Process for workup of a stream comprising butene and/or butadiene
The invention relates to a process for workup of a stream (1) comprising butene and/or butadiene, butane, hydrogen and/or nitrogen and carbon dioxide, comprising: (a) absorption of stream (1) with a mixture (5) comprising 80 to 97% by weight of N-methylpyrrolidone and 3 to 20% by weight of water to obtain a stream (9) comprising N-methylpyrrolidone, water, butene and/or butadiene, butane, and optionally carbon dioxide, and a stream (7) comprising hydrogen and/or nitrogen and butane, (b) extractive distillation of stream (9) with a stream (13) comprising 80 to 97% by weight of N-methylpyrrolidone and 3 to 20% by weight of water to separate the stream (9) into a stream (17) comprising N-methylpyrrolidone, water, butene and/or butadiene, and a stream (15) comprising essentially butane, and optionally carbon dioxide, (c) distillation of stream (17) into a stream (23) comprising essentially N-methylpyrrolidone and water, and a stream (21) comprising butene and/or butadiene.
US08420878B2 Complex oxide catalyst of Bi/Mo/Fe for the oxidative dehydrogenation of 1-butene to 1,3-butadiene and process thereof
The present invention relates to a complex oxide catalyst of Bi/Mo/Fe and an oxidative dehydrogenation of 1-butene in the presence of a catalyst herein. A catalyst of the present invention is superior to the conventional Bi/Mo catalyst in thermal and mechanical stabilities, conversion and selectivity toward 1,3-butadiene, while showing a long-term catalytic activity.
US08420877B2 Process for ethylbenzene production
A method of producing an alkylaromatic by the alkylation of an aromatic with an alkylating agent, such as producing ethylbenzene by an alkylation reaction of benzene, is disclosed. The method includes using an H-beta catalyst in a preliminary alkylation reactor that is located upstream of the primary alkylation reactor. The H-beta catalyst used in a preliminary alkylation reactor can be regenerated and the regenerated H-beta zeolite catalyst can have a deactivation rate that is no more than 120% of the deactivation rate of a fresh H-beta zeolite catalyst.
US08420873B2 Process for preparing 2,3,3,3-tetrafluoropropene
The present invention provides a process for producing 2,3,3,3-tetrafluoropropene including the step of dehydrofluorinating 1,1,1,2,3-pentafluoropropane, wherein 1,3,3,3-tetrafluoropropene and 1,1,3,3,3-pentafluoropropane are supplied together with 1,1,1,2,3-pentafluoropropane to a reactor containing a catalyst to simultaneously perform dehydrofluorination reaction and isomerization reaction.According to the process of the present invention, 2,3,3,3-tetrafluoropropene (HFO-1234yf) can be efficiently produced by effectively using the by-products of the dehydrofluorination reaction.
US08420869B2 Process for the preparation of 2,2,4,4-tetraalkylcyclobutane-1,3-diols
Disclosed is a process for the preparation of a 2,2,4,4-tetraalkylcyclobutane-1,3-diol by hydrogenation of the corresponding 2,2,4,4-tetraalkylcyclobutane-1,3-dione in the vapor phase in the presence of a supported catalyst. The process is useful for the preparation of 2,2,4,4-tetramethylcyclobutane-1,3-diol from 2,2,4,4-tetramethylcyclobutane-1,3-dione. The process can produce a 2,2,4,4-tetraalkylcyclobutane-1,3-diol product having a cis:trans isomer ratio of 1:1 or greater.
US08420865B2 Phosphine compound, process for producing the same, and peroxide scavenger using the same
The invention provides a novel peroxide scavenger comprising a phosphine compound represented by general formula [I]: wherein Z1 and Z2 each represents a cyclic group; Ar represents an arylene group; R represents an aliphatic hydrocarbon group; Y represents phosphorus (P), nitrogen (N), or bismuth (Bi); and R1, R2, and R3 each represents a cyclic group, particularly a peroxide scavenger that can scavenge peroxides such as reactive oxygen species which are generated in mitochondria upon exposure to oxidative stress and localized in mitochondria. The phosphine compound of the invention is oxidized by the peroxides localized in mitochondria to increase the fluorescence intensity, whereby the peroxides can be scavenged.
US08420861B2 Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone
Compounds for utilization as anti-tumor agents against cancer and certain inflammatory and arthritic conditions designed with multiple active sites to cause inhibition and cell death synthesized from the starting compound 1,4,5,8-tetrachloroanthraquinone. Included are anti-tumor compounds of the class 1,4,5,8-tetrakis-alkylaminoalkyl, 1,4,5,8-tetrakis-hydroxyalkylaminoalkyl, 1,4,5,8-tetrakis-chloroethylamino, 1,2-bischloroethylamino-1,4,5,8-tetrakis-aminoethylamino derivatives of Anthraquinone. Also includes mixtures of groupings such as 1-aminoalkylamino-4,5,8-tris-(1,2-dimethyl)aminoalkylamino anthraquinone, 1,2-dichloroethyl 1-aminoalkyl amino-4,5,8-tris-aminoethylamino anthraquinone, bis-1,4aminoalkylamino bis-5,8-alkylaminoanthraquinone, 1,4-bis-chloroalkylamino-5,8-bisaminoalkylamino anthraquinone and others.
US08420860B2 Compound and color filter
The present invention provides a triarylmethane compound and a color filter containing the compound in a blue pixel portion, the triarylmethane compound being capable of providing a colored material which causes little change in hue over a long period of time even under high temperature or light irradiation. For example, when used for preparing a blue pixel portion of a color filter, the triarylmethane compound is capable of providing a liquid crystal display device or the like which can provide a high-brightness liquid crystal display having excellent brightness over a long period of time even under high temperature or light irradiation. The triarylmethane compound contains, as a counter anion for a basic triarylmethane dye cation, a heteropolyoxometalate anion represented by (P2MoyW18-yO62)6−/6 wherein y=an integer of 1, 2, or 3, and the color filter contains the triarylmethane compound in a blue pixel portion.
US08420859B2 Formulations
This invention relates to the use of lactamide compounds of formula (I): CH3CH(OH)C(═O)NR1R2, where R1 and R2 are each independently hydrogen; or C1-6 alkyl, C2-6 alkenyl or C3-6 cycloalkyl, each of which is optionally substituted by up to three substituents independently selected from phenyl, hydroxy, C1-5 alkoxy, morpholinyl and NR3R4 where R3 and R4 are each independently C1-3 alkyl; or phenyl optionally substituted by up to three substituents independently selected from C1-3 alkyl; or R1 and R2 together with the nitrogen atom to which they are attached form a morpholinyl, pyrrolidinyl, piperidinyl or azepanyl ring, each of which is optionally substituted by up to three substituents independently selected from C1-3 alkyl, in formulations to reduce the toxicity associated with other formulation components; to the use of certain lactamide compounds as solvents, especially in formulations, particularly in agrochemical formulations and in environmentally friendly formulations; to novel lactamide compounds; and to processes for preparing lactamide compounds.
US08420857B2 Removal of silica from water soluble compounds by nanofiltration and reverse phase chromatography
A process for separating soluble silica species such as monomeric silicic acid (or monosilicic acid) and low molecular weight soluble polymeric silica from impure water soluble compounds by membrane nanofiltration is provided. A process for separating soluble silica species and colloidal silica from impure water soluble compounds by reverse phase liquid chromatography is also provided.
US08420848B2 Process for the synthesis of beta glycerol phosphate
The present invention provides methods for the preparation of beta glycerol phosphate and its salts. In particular, the invention provides efficient methods for the synthesis of beta glycerol phosphate of high purity.
US08420847B2 Bis-phosphate compound and asymmetric reaction using the same
A novel bis-phosphate compound is provided which can be applied to a wide range of reactive substrates and reactions as an asymmetric reaction catalyst and can realize an asymmetric reaction affording a high yield and a high enantiomeric excess. The bis-phosphate compound has a tetraaryl skeleton represented by General Formula (1). In an asymmetric reaction, an amidodiene and an unsaturated aldehyde compound are reacted with each other in the presence of the optically active bis-phosphate compound to give an optically active amidoaldehyde. The invention allows a reaction such as an asymmetric Diels-Alder reaction to proceed efficiently, which has been difficult with conventional mono-phosphate compounds. Thus, the invention enables an industrially feasible method for the production of optically active amidoaldehydes, optically active β-amino acid derivatives, optically active diamine compounds, optically active pyrrolidine derivatives and optically active dihydropyran derivatives which are useful as products such as medicines, agricultural chemicals and chemical products as well as synthesis intermediates for such products.
US08420845B2 Functional substance-releasing agent
Disclosed are: a functional material release agent including 35% to 95% by mass of the silicate ester compound represented by formula (1) and 0% to 40% by mass of the silicate ester compound represented by formula (2); a method for manufacturing the release agent; and compositions containing the release agent. (In the formula, R1 is an aliphatic hydrocarbon group with a total of 4 to 22 carbon atoms, that may contain a phenyl group, a hydroxyl group, or an alkoxy group as a substituent; R2 is the residue of functional alcohol minus one hydroxyl group; and R3 is a hydrogen atom or an alkyl group with one to six carbon atoms.)
US08420844B2 Hydrosilylation process for gaseous unsaturated hydrocarbons
Organosilicon compounds are prepared by the addition reaction of a gaseous unsaturated hydrocarbon with a silane or siloxane containing at least one silicon-bonded hydrogen atom in the presence of a hydrosilylation catalyst in a liquid reaction medium. In this process the unsaturated hydrocarbon and optionally the silane or siloxane is dispersed into the liquid reaction medium by a jet eductor (also known as a venturi pump) device and the resultant gas-in-liquid dispersion is introduced into a bubble reactor.
US08420841B2 Methods and systems to produce biodiesel fuel
A method of manufacturing a biodiesel fuel that comprises generating micro-droplets of a first reactant and mixing the micro-droplets of the first reactant with a second reactant that is substantially immiscible with the first reactant. The method also comprises transferring the mixture of the first reactant and second reactant into a transesterification reaction vessel. The first reactant is one of an alcohol or oil, and the second reactant is the other of the oil or the alcohol.
US08420832B2 Optically active methylhydroxylaminopropanol derivative and its use as intermediate for preparation of (S)-(-)-3-methylamino-1-(-2-thienyl)propan-1-ol
The present invention provides an (S)-methylhydroxylaminopropanol compound and the (S)-methylhydroxylaminopropanol compound of the present invention is used as an intermediate for preparation of (S)-(−)-3-methylamino-1-(2-thienyl)propan-1-ol, which is an intermediate for preparation of (S)-(+)-N-methyl-3-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine oxalate. The present invention also provides a process for preparing (S)-(+3-methylamino-1-(2-thienyl)propan-1-ol with higher yield and lower cost, wherein the (S)-methylhydroxylaminopropanol compound is used as an intermediate.
US08420828B2 Inhibitors
Novel heterocyclic derivatives as inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.
US08420825B2 Alkylamino-substituted dicyanopyridines and their amino acid ester prodrugs
The present application relates to novel 6-alkylamino-substituted dicyanopyridines, to their amino acid ester prodrugs, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders.
US08420819B2 Process for optimizing the particle size of an active pharmaceutical ingredient by crystallization
A process to crystallize uniform small particles of a compound of Formula (I) with narrow particle size distribution and excellent powder characteristics that facilitate the formulation process and optimal drug product performance, wherein the compound of Formula (I) is: wherein R1, R2, and R3 are as described herein.
US08420818B2 Process for the preparation of pyrido[2,1-a] isoquinoline derivatives
The present invention relates to a novel process for the preparation of pyrido[2,1-a]isoquinoline derivatives of the formula wherein R2, R3 and R4 are each independently selected from the group consisting of hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy and lower alkenyl, wherein lower alkyl, lower alkoxy and lower alkenyl may optionally be substituted by a group consisting of lower alkoxycarbonyl, aryl and heterocyclyl, and the pharmaceutically acceptable salts thereof. The pyrido[2,1-a]isoquinoline derivatives of the formula I are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV.
US08420812B2 Process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates
A process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonatesThe present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein D, J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process of heteroaryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional heteroaryl-1-alkynes of the formula I.
US08420801B2 Recovery of nucleic acids from magnetic glass particles
The present invention is a method of separating nucleic acids using a solid phase capable of binding nucleic acids, such as magnetic glass particles, where binding of nucleic acids to the solid phase is enhanced by the presence of an ethylene-amine compound. The invention further includes a reaction mixture for isolating nucleic acids containing an ethylene-amine compound and kits for carrying out the method.
US08420800B2 Head-and-neck tumor proliferation inhibitor
It is to provide a novel head-and-neck tumor proliferation inhibitor, head-and-neck tumor metastasis inhibitor and pharmaceutical composition for treating a head-and-neck tumor. The present invention is characterized by using an inhibitory substance of a microRNA whose expression increases in a head-and-neck tumor and/or a promoting substance of a microRNA whose expression decreases in a head-and-neck tumor. Preferred examples of the microRNA whose expression increases in a head-and-neck tumor include miR-455-3p, miR-455-5p, miR-130b, miR-130b*, miR-801, miR-196a, miR-21 and miR-31. Preferred examples of the microRNA whose expression decreases in a head-and-neck tumor include miR-133b, miR-145 and miR-375.
US08420789B2 Method for removing DNA contaminants from a protein-containing sample
A method is provided for purifying physiologically active proteins, especially antibodies, in order to remove impurities such as DNA contaminants and viruses with minimal loss of physiologically active proteins. The physiologically active protein is introduced into an aqueous solution of low conductivity at a pH of below the isoelectric point of the physiologically active protein to precipitate impurities as particles. The particles are removed, leaving a purified physiologically active protein.
US08420782B2 Modular DNA-binding domains and methods of use
The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of the polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.
US08420780B2 Mutated netrin 4, fragments thereof and uses thereof as drugs
Proteins having the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 4, or fragments of said sequences are provided. The protein fragments are represented by the sequences of SEQ ID NO: 2q, q varying from 3 to 36, and the sequences of SEQ ID NO: 185 to SEQ ID NO: 209. Nucleotide sequences coding for said proteins are also provided.
US08420779B2 Compositions and methods for producing bioactive fusion proteins
Disclosed is a composition of matter involving a recombinant fusion protein comprising a a pharmacologically active protein partner, and a small pharmacologically inactive protein domain partner of human origin, such as but not limited to, a 10th fibronectin III domain, a SH3 domain, a SH2 domain, a CH2 domain of IgG1, a PDZ domain, a thrombospondin repeat domain, an ubiquitin domain, a leucine-rich repeat domain, a villin headpiece HP35 domain, a villin headpiece HP76 domain, or a fragment or modification of any of these. Also disclosed are nucleic acids (e.g., DNA constructs) encoding the fusion protein, expression vectors and recombinant host cells for expression of the fusion protein, and pharmaceutical compositions containing the recombinant fusion protein and a pharmaceutically acceptable carrier, and method of producing a pharmacologically active recombinant fusion protein.
US08420777B2 Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
US08420776B2 Ube2G2 binding domain in the ubiquitin ligase gp78 and methods of use thereof
The present invention features isolated nucleic acid molecules, designated G2BD nucleic acid molecules, which encode the binding site from the gp78 ubiquitin ligase that binds to the Ube2G2 ubiquitin conjugating enzyme. The invention further provides isolated G2BD proteins and fusion proteins. Still further provided are diagnostic and therapeutic methods, as well as screening assays utilizing compositions of the invention.
US08420768B2 Polymerizable higher diamondoid derivatives
Higher diamondoid derivatives capable of taking part in polymerization reactions are disclosed as well as intermediates to these derivatives, polymers formed from these derivatives and methods for preparing the polymers.
US08420765B2 Spandex from poly(tetramethylene-co-ethyleneether)glycols blended with polymeric glycols
A polyurethaneurea composition comprises a reaction product of at least one diisocyanate compound, a polymeric glycol, a poly(tetramethylene-co-ethyleneether) glycol comprising constituent units derived by copolymerizing tetrahydrofuran and ethylene oxide (EO) wherein the portion of the constituent units derived from ethylene oxide is present in the poly(tetramethylene-co-ethyleneether) glycol from greater than about 37 to about 70 mole percent, at least one diamine chain extender, and at least one chain terminator. The invention further relates to the use of blends of polymeric glycols and poly(tetramethylene-co-ethyleneether) glycols as the soft segment base in spandex compositions. The invention also relates to new polyurethane compositions comprising polymeric glycols and poly(tetramethylene-co-ethyleneether) glycols, and their use in spandex.
US08420762B2 Silicone resin composition and a cured product thereof
The present invention provides a silicone resin composition comprising (A) an organopolysiloxane having at least two alkenyl groups, (B) an organohydrogenpolysiloxane having at least two hydrogen atoms each bonded to a silicon atom, (C) a catalyst comprising a platinum group metal, (D) fine silicone particles, and (E) a (meth)acrylate compound. The present silicone resin composition cures in a short time to form a cured product having excellent adhesion strength with solder resists and copper substrates.
US08420761B2 Compounds having a guanidine structure and use of same as organopolysiloxane polycondensation catalysts
The present invention relates to an organopolysiloxane composition that can be vulcanized at room temperature into an elastomer that is crosslinked by polycondensation and that does not contain alkyltin-based catalysts which exhibit toxicity problems. The invention also relates to novel polycondensation catalysts having a guanidine structure, in silicone chemistry, and to the uses thereof as catalysts for the organopolysiloxane polycondensation reaction.
US08420760B2 Long chain branched propylene-alpha-olefin copolymers
Substantially isotaclic propylene interpolyraets comprise (A) at least 60 weight percent (wt %) units derived from propylene, and (B) between greater than zero and 40 wt % units derived from ethylene, the propylene interpolyrner further characterized by at least one of the following properties: (1) a ratio of less than 1 measured at interpolyraer number average molecular weight (Mn), (2) a relative compositional drift of less than 50%, arid (3) propylene chain segments having a chain isotacticity triad index of at least 70 mole percent.
US08420757B1 Chelating compound and the corresponding acid
A polymer comprising a polymer backbone. The polymer backbone has a plurality of carbon atoms. There are two lipophobic carboxylate groups or carboxylic acid groups per repeating unit being coupled to separate carbon atoms of the backbone. The polymer may be used to recover metals by chelation and then burning away the polymer.
US08420755B2 Compounds, catalyst composition comprising the same, and method for preparing of cycloolefin-based polymer using the same
The present invention relates to a novel metallocene compound, a catalyst composition including the compound and an olefin polymer prepared using the same. The metallocene compound and the catalyst composition can be used for preparing the olefin polymer with high copolymerization degree and high molecular weight. Particularly, the block copolymer with high heat resistance can be prepared by using the metallocene compound, and the olefin polymer with high melting point (Tm) can be obtained, even if co-monomer is used at an increased amount in preparation of olefin polymer.
US08420752B2 Production method and production apparatus of particulate water absorbing agent containing water absorbent resin as main component
An apparatus (2) includes a neutralization tank (3), a pump (4), a heat exchanger (6), a line mixer (8), a polymerizer (10), a first pipe (12), a second pipe (14), a third pipe (16), a fourth pipe (18), and a fifth pipe (20). Continuously supplied into the neutralization tank (3) are a monomer aqueous solution and a basic aqueous solution, so as to prepare a mixture solution. The mixture solution is circulated through the first pipe (12), the pump (4), the second pipe (14), the heat exchanger (6), and the third pipe (16). The mixture solution is supplied to the polymerizer through the fourth pipe (18). The apparatus (2) satisfies a requirement that a value X is not more than 200, which value X is found according to the following expression: “X=(V/F)·A”, wherein V is a volume of the mixture solution present in a neutralization system, F is a flow volume of the mixture solution to be supplied to a polymerization system, and A is a contact area of the mixture solution present in the neutralization system with a device(s) and a pipe(s) constituting the neutralization system. With this arrangement, it is possible to provide a water absorbent resin having superior whiteness.
US08420750B2 Copolymers of dibendiazocine with difunctional monomers containing sulfone and/or ketone units
Copolymers comprising recurring units (A) of one or more of the general structural formulae -D-G-Arb-G-, -G-D-G-Arb- and/or -D-G- on one hand, and recurring units (B) of one or more of the general structural formulae —Ara-G-Arb-G-, -G-Ara-G-Arb- and/or —Ara-G- on the other hand, wherein D is a dibenzodiazocine-containing divalent group, Ara is a dibenzodiazocine-free divalent group containing a sulfone unit and/or a ketone unit, Arb is a dibenzodiazocine-free divalent group, and G is an ether or a thiether group. Preferably, recurring units (A) are of the general structural formula -D-G-Arb-G- and recurring units (B) are of the general structural formula —Ara-G-Arb-G-. Method for the preparation of the copolymers, compositions and articles made of the copolymers are also part of the invention.
US08420749B2 Epoxy resin composition and cured article thereof, semiconductor encapsulation material, novel phenol resin, and novel epoxy resin
The object of the present invention is to provide an epoxy resin composition capable of realizing low dielectric constant and low dielectric dissipation factor, which is suited for use as a latest current high-frequency type electronic component-related material, without deteriorating heat resistance during the curing reaction. A phenol resin, which has the respective structural units of a phenolic hydroxyl group-containing aromatic hydrocarbon group (P) derived from phenols, an alkoxy group-containing condensed polycyclic aromatic hydrocarbon group (B) derived from methoxynaphthalene and a divalent hydrocarbon group (X) such as methylene and also has a structure represented by —P—B—X— wherein P, B and X are structural sites of these groups in a molecular structure, is used as a curing agent for the epoxy resin, or a phenol resin as an epoxy resin material.
US08420746B2 Biodegradable composition and foam article made therefrom
A biodegradable composition includes: a polymer component including a first polymer of polybutylene-1,4-succinate (PBS); and a cross-linking agent capable of producing a free radical to allow the polymer component to be subjected to a free radical cross-linking reaction in such a condition that the biodegradable composition has a melt index ranging from 1.5 to 3.0.
US08420745B2 Thermally curable solder resist composition
A thermally curable solder resist composition for a flexible printed circuit board is provided. The solder resist composition includes (a) 50-100 parts by weight of an epoxy resin, wherein the epoxy resin includes at least an aliphatic polyester modified epoxy resin having formula (I) or (II), in which, each of R1 and R2, independently, is a C6-38 saturated or an unsaturated carbon chain, R3 is ether, phenyl, a C6-38 heterocyclic or C6-38 saturated carbon chain, n is an integer of 1-10 and the aliphatic polyester modified epoxy resin had a molecular weight of 1000-5000; (b) 1-10 parts by weight of a curing agent; and (c) 1-10 parts by weight of a catalyst.
US08420735B2 Modified microfibrillated cellulose and resin composite material containing the same
A modified microfibrillated cellulose, a resin composition and a resin composite material that contain the modified microfibrillated cellulose are provided. In a modified microfibrillated cellulose according to the present invention, a hydrolyzable-silyl-group-containing resin (A) bonds to or adheres to a cellulose surface and a silicon atom content is 0.01 to 0.5 atomic percent. A resin composition containing 0.1% to 10% by weight of the modified microfibrillated cellulose is also provided.
US08420729B2 Method of preparing phenolic resin/carbon nano materials (hybrid resin)
It is disclosed a method for preparing a nano hybrid resin containing carbon nano materials as graphitizing agents with predetermined characteristics by formation of graphite phase in residual carbon.
US08420720B2 Rubber composition for clinch, chafer or sidewall, and pneumatic tire
The present invention provides a rubber composition for a clinch, a chafer or a sidewall, which improves fuel economy, elongation at break, and abrasion resistance in good balance while maintaining good handling stability (hardness) and processability (extrusion processability) even if the amount of zinc oxide is decreased; and a pneumatic tire having a clinch, a chafer and/or a sidewall produced therefrom. The invention relates to a rubber composition for a clinch, a chafer or a sidewall, comprising: a rubber component; a compound represented by formula (I): wherein R1 to R4 each independently represent a C1-18 linear or branched alkyl group or a C5-12 cycloalkyl group; and zinc oxide, wherein the amount of the compound represented by formula (I) is 0.2 to 6 parts by mass and the amount of the zinc oxide is 1.0 part by mass or less, for each 100 parts by mass of the rubber component.
US08420719B2 Phosphorus-containing flame retardants
A flame-retardant resin composition comprises a base resin (A), such as a polyester or polycarbonate resin, and an aromatic organophosphorus compound, in particular, aromatic organophosphorus oligomers or polymers.
US08420715B2 Encapsulated colorant and ink composition including the same
An encapsulated colorant including a colorant and a polymer resin coating the colorant, where the polymer resin is prepared by polymerizing a polymer resin-forming composition including two or more polymerizable unsaturated monomers, and the content ratio of the two or more polymerizable unsaturated monomers is controlled to obtain a glass transition temperature of the polymer resin of −15 to 75° C. An ink composition including an encapsulated colorant, and an ink set comprising two or more types of the ink composition. The encapsulated colorant may have different glass transition temperatures to have a utility of high optical density when printing text, and high gloss when printing images.
US08420714B2 Ink composition, and inkjet recording method
An ink composition comprising: (A) an isoindoline-based pigment; (B) a polymeric dispersant; (C) an alkylammonium salt of a sulfonated derivative of a disazo-based yellow colorant; (D) a polymerizable compound; and (E) a polymerization initiator.
US08420703B2 Method for separating and removing foreign matters from polyester fiber waste
The purpose of the present invention is to provide a method for collecting effective components from polyester fiber waste containing polyalkylene telephthalate as the main component, more specifically to provide a method for separating and removing foreign matters (mainly cotton) contained in polyester fiber waste. The purpose of the invention can be achieved by a method for separating and removing foreign matters from polyester waste, which includes throwing polyester fiber waste that contains polyalkylene telephthalate as the main component and foreign matters other than the polyalkylene telephthalate into a depolymerization reaction tank, subjecting a part or all of the polyester fiber to a depolymerization reaction with alkylene glycol to give a depolymerization reaction liquid, and then continuously or intermittently feeding the liquid to a foreign matter-separating and removing apparatus having specified characteristics.
US08420702B2 Process for recycling articles based on a fiber reinforced polymer
Process for recycling a fiber reinforced polymer article, according to which the article, eventually cut in fragments, is dissolved in a solvent capable of dissolving the polymer but not the fibers and which is susceptible of forming an azeotrope with water, forming a solution; the fibers are recovered from the solution; the fibers are washed with solvent by putting them in the form of a slurry in the solvent and by agitating the slurry and/or by making the solvent circulate through it; the washed fibers are recovered from the slurry; and the recovered fibers are submitted to a stripping with steam in order to substantially remove the solvent.
US08420699B1 Composition and methods of treatment using deionized and ozonated solution
Therapeutically effective compositions and methods to inhibit dry eye as well as other conditions are provided. A therapeutically effective composition consists of at least one surfactant; a preservative with reduced immunogenicity relative to thimerosol; a complexing agent; and deionized, demineralized, ozonated water.
US08420696B2 Use of low-dose ladostigil for neuroprotection
The subject invention provides a method of preventing a neurodegenerative disease in a subject or oxidative stress in the brain of a subject, comprising administering to the subject a less than cholinesterase-inhibitory amount or a less than monoamine oxidase-inhibitory amount of R(+)-6-(N-methyl,N-ethyl-carbamoyloxy)-N′-propargyl-1-aminoindan or a salt thereof effective to prevent the neurodegenerative disease or oxidative stress in the subject.
US08420692B1 Heterocyclic and carbonate derivatives of NDGA and their use as new anti-HIV and anti-cancer agents
Reaction of nordihydroguaiaretic acid with various alkyl chlorides, 1-piperidinecarbonyl chloride, methyl chloroformate, or 1,1′-carbonyldiimidazole under alkaline conditions produced the corresponding phenol ethers, carbamates and carbonates, respectively, in 67-83% yields (Scheme 1 and Scheme 2). Among these derivatives, the nitrogen-containing compounds were converted to the corresponding hydrochloride salts. Having good solubility, these NDGA derivatives were found to be stable in aqueous solution. These new compounds exerted potent activities against HIV Tat-regulated transactivation in cos-7 cells. The most active transcription inhibitor compound of this series 5b (P4N, Tetrapiperidino NDGA, meso-2,3-dimethyl-1,4-bis(3,4-[2-(piperidino)ethoxypehnyl])butane tetrakishydrochloride salt) has an IC50 of 0.88 μM.
US08420687B2 Pharmaceutical composition
To provide a pharmaceutical composition which can enhance the storage stability of 1-(1-hydroxymethyl-2,3-dihydroxypropyloxymethyl)-2-nitroimidazole without impairing the effect of the compound.The pharmaceutical composition includes 1-(1-hydroxymethyl-2,3-dihydroxypropyloxymethyl)-2-nitroimidazole, which is represented by formula (1): and a compound having chelating ability.
US08420686B2 Linked diimidazole antivirals
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US08420684B2 Inhibitors of glutaminyl cyclase
The present invention relates to compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof wherein R1 represents heteroaryl; -carbocyclyl-heteroaryl; -alkenylheteroaryl or -alkylheteroaryl; R2 represents alkyl which may optionally be substituted by hydroxy; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl and hydroxy; aryl; -aryl-heteroaryl; -heteroaryl-aryl; -aryl-heterocyclyl; H; heteroaryl; or heterocyclyl, which may optionally be substituted by one or more groups selected from alkyl oxo and hydroxy; R3 represents alkyl which may optionally be substituted by one of more groups selected from alkoxy, amine, hydroxy and —C(O)Oalkyl; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl haloalkyl, alkoxy, amine, hydroxy and —C(O)Oalkyl; -alkyl-aryl; -alkyl(aryl)2; -alkyl-heteroaryl; -alkyl(heteroaryl)2; -alkyl(heteroaryl)(aryl); -aryl-O-aryl; aryl; heterocyclyl, -alkyl-C(O)-heterocyclyl, -alkyl-heterocyclyl, -alkyl-C(O)—NR5-heterocyclyl or -alkyl(heterocyclyl)2 in any of which groups heterocyclyl may be optionally substituted by one or more groups selected from alkyl hydroxy and oxo; -heteroaryl; or -hydroxyalkylaryl; R4 represents H or C1-3 alkyl; R5 represents H or C1-3 alkyl; and X represents O or S.
US08420682B2 N-phenylacetamide derivatives, which inhibit the enzyme SOAT-1, and pharmaceutical and cosmetic compositions containing them
Compounds of general Formula (I), and cosmetic and pharmaceutical compositions including such a compound are described.
US08420680B2 NMDA receptor antagonists for neuroprotection
Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of disorders associated with NMDA receptor activity, including neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided: wherein: each (L)k-Ar1 is a substituted or unsubstituted, mono or bicyclic aryl or heteroaryl; W is a bond, alkyl, or alkenyl; X is a bond, NR1 or O and each R1 and R2 is independently H, alkyl, alkenyl or aralkyl or R1 and R2 taken together form a 5-8 membered ring; R3−R6 are selected from certain specific substituents or a carbonyl; Y is a bond, O, S, SO, SO2, CH2, NH, N(alkyl), or NHC(═O); and Z is OH, NR6R7, NR8SO2(alkyl), NR8C(O)NR6R7, NR8C(O)O(alkyl), NR8-dihydrothiazole, or NR8-dihydroimidazole or wherein Z can fuse with Ar2 to form selected heterocycles.
US08420675B2 Aminotetrahydroindazoloacetic acids
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, W, X, R1—R5 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
US08420674B2 Method of providing pirfenidone therapy to a patient
The invention relates to methods for decreasing adverse events associated with pirfenidone (5-methyl-1-phenyl-2-(1H)-pyridone) therapy. The invention discloses an optimized dose escalation scheme that results in the patient having increased tolerance to adverse events associated with the administration of pirfenidone. The invention also discloses a starter pack that may be used in conjunction with the dose escalation scheme.
US08420670B2 4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy
The present invention relates to 4-benzylaminoquinolines of the formula (I) or physiologically tolerated salts thereof. The invention relates to pharmaceutical compositions comprising such quinolines, and the use of such quinolines for therapeutic purposes. The quinolines are GIyTI inhibitors.
US08420662B2 Stable solid preparation containing 4,5-epoxymorphinan derivative
It is an object of the present invention to provide a stable solid preparation comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an effective ingredient.That is, the present invention provides the stable solid preparation comprising the 4,5-epoxymorphinan derivative or the pharmacologically acceptable acid addition salt thereof as the effective ingredient, and comprising sodium thiosulfate, a sugar or a sugar alcohol and hydroxypropylcellulose having a low degree of substitution in an amount of 1 to 30% by weight per weight of a unit containing the effective ingredient.
US08420659B2 Compositions and methods for inhibition of the JAK pathway
The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, are therapeutically useful.
US08420658B2 Use of Carboxyamidotriazole (CAI) orotate in macular degeneration
Method and composition of Carboxyamidotriazole orotate for treating age-related macular degeneration and other angiogenesis-dependent diseases.
US08420656B2 Substituted 5-fluoro-1H-pyrazolopyridines and their use
The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
US08420652B2 Use of aryl piperazine derivatives in manufacturing medicants for treating pain
The use of aryl piperazines of formula (I) in manufacturing a medicament for treating acute pain, neuropathic pain or receptive nociceptive pain in mammals including human beings is disclosed.
US08420647B2 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
US08420645B2 Salts of 2-fluoro-N-methyl-4-[7-(quinolin-6-yl-methyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same
The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.
US08420641B2 Method of inhibiting CETP activity with 4-benzylamino-1-carboxylacyl-piperidine derivatives
The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R5, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.
US08420640B2 Methods of treating amyloid disease using analogs of 1-(4-nitrophenyl) piperazine
The present invention is directed to compounds that inhibit amyloid aggregation and methods of treatment therewith.
US08420637B2 Abnormal cannabidiols as agents for lowering intraocular pressure
The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
US08420636B2 Pyrrolidinyl-alkyl-amide derivatives, their preparation, and their therapeutic application as CCR3 receptor ligands
The present invention relates to pyrrolidinyl-alkyl-amide derivatives of formula (I) or (IA) wherein the variables are as defined herein, to their preparation and to their therapeutic use as CCR3 receptor ligands.
US08420634B2 Amidine, thiourea and guanidine derivatives of 2-aminobenzothiazoles and aminobenzothiazines for their use as pharmacological agents for the treatment of neurodegenerative pathologies
Amidine, thiourea and guanidine derivatives of appropriately substituted 2-aminobenzothiazoles, 2-amino-3,1-4H-benzothiazines and 3-amino-1,4-3H-benzothiazines, as understood from formula (I), the related pharmaceutically acceptable salts and solvates thereof: and the use of the products and the corresponding pharmaceutical formulations for the treatment of neurodegenerative pathologies such as cerebral ischemia, neurodegeneration induced by cranial trauma, Alzheimer's disease, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
US08420632B2 Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
US08420631B2 6-substituted-2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2C receptor agonists for the treatment of 5-HT2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where R6 is —C≡C—R10, —CH═CR11R11′, or —(C0-C8)alkyl-Ar2 optionally substituted on the alkyl moiety with 1 to 6 fluoro substituents and other substituents are as defined in the specification.
US08420622B2 Silylated piperidine derivatives
Compounds of formula I: I wherein at least one of R4 and R5 comprises Si(R6)3 as a substituent selectively attenuate production of Aβ(1-42) and hence find use in treatment of Alzheimer's disease and related conditions.
US08420619B2 Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein
The invention provides methods for treating ocular diseases using a recombinant vehicle to express a protein useful in the treatment of ocular disease, with particular preference for use of neurotrophin-4 (NT4) for targeting subpopulations of cells in the retina. A genetically engineered gene transfer vector containing sequences encoding a growth factor such as neurotrophin-4 (NT4) is used to transduce cells of the retinal ganglion cell (RGC) layer, in situ, via administration of the vector intravitreally. Accordingly, methods are disclosed for treating subjects in need thereof by therapeutic protein delivery via a recombinant expression vector, including rescue of photoreceptors by targeting the RGC layer subpopulation of retinal cells.
US08420616B2 MAT II β subunit RNAi and therapeutic methods using same
The presently disclosed subject matter generally relates to methods and compositions for modulating MAT II activity. More particularly, the presently disclosed subject matter relates to methods and compositions for inhibiting the expression of MAT II β subunit in a subject via RNAi by administering siRNA or shRNA molecules directed to MAT II β subunit. In some embodiments, the methods and compositions of the presently disclosed subject matter generally relates to the treatment of cancer. More particularly, the methods and compositions of the presently disclosed subject matter relates to the inhibition of MAT II β subunit for the treatment of leukemia.
US08420613B2 Methods and compositions for reducing amyloid beta levels
The present invention provides methods for reducing the level of amyloid beta protein in a cell or tissue, the methods generally involving contacting the cell or tissue with an agent that reduces cystatin C levels and/or activity. The present invention provides methods for treating Alzheimer's disease (AD), and methods for treating cerebral angiopathy, in an individual, the methods generally involving administering to an individual having AD a therapeutically effective amount of an agent that reduces cystatin C levels and/or activity. The present invention further provides methods for identifying an agent that reduces cystatin C levels and/or activity.
US08420612B2 Diabetes treatment methods and drug targets therefor
Provided are methods of treating insulin resistance or type II diabetes. Disrupting CAP in the macrophage can alter the inflammatory response associated with impaired insulin action and ultimately result in improved insulin action in target tissues. One aspect of the invention involves administering a CAP antagonist to a patient afflicted with insulin resistance or type II diabetes in an amount sufficient to improve insulin action in target tissues.
US08420610B2 Polyunsaturated compounds, method for preparing same and compositions containing the same
The invention concerns novel polyunsaturated compounds of formula (I) wherein: R1 represents a R′1, -A-R′1 group, R′1 being selected from —COOH, —COOR3, —CONH2, —CONHR3, —CONR3 R4, —CHO, —CH2OH, —CH2OR5, and A represents a C2-C16 alkylene, alkenylene or alkynylene; R2 represents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a —OC —(CH2)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a —R′2—O—R6 group, wherein R′2 is an optionally substituted arylene group or an optionally substituted heteroarylene group, and R6 represents a hydrogen atom, a straight or branched optionally substituted C 1-C 16 alkyl, a straight or branched optionally substituted C2-C16 alkenyl, or a straight or branched C2-C16 alkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.
US08420605B2 Hydrogel compositions
Hydrogel compositions comprise an aqueous dispersion phase and a plurality of peptides, or derivatives, or analogues thereof. Each peptide comprises at least two amino acid residues and an aromatic stacking ligand and the hydrogel is formed by self-assembly of said peptides in said aqueous dispersion medium. The aqueous dispersion phase is physiologically acceptable and may have a pH of 6 to 8, as may the hydrogel itself. The hydrogel may be used for cell culture or for treatment of medical conditions characterized by tissue loss/damage.
US08420603B2 SPARC and methods of use thereof
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying the SPARC protein or RNA in a sample isolated from the mammal. The invention further provides kit for predicting the response of a mammalian tumor to a chemotherapeutic agent, comprising a means for the isolation of protein or RNA from the tumor, a SPARC protein or RNA detection and quantification means, control RNAs, and rules for predicting the response of the tumor based on the level of SPARC protein or RNA in tumor.
US08420596B2 Macrocyclic hepatitis C serine protease inhibitors
The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
US08420589B2 Composition for textile softener having low temperature activity and textile softener sheet comprising the same
Disclosed is a composition for textile softener containing a cationic surfactant, the ratio of which C7-C21 alkyl substituents analyzed by HLPC (high pressure liquid chromatography) or GC (gas chromatography) is 0.6 or more, as an effective ingredient, a sheet for textile softener including the same, and method of softening a textile using the sheet. Since the composition for textile softener has excellent dissolving and dispersing effect even in low temperature water, the sheet containing this composition is used at a rinse time during washing procedures to represent excellent anti-static effect and textile softening effect to textiles and clothes.
US08420588B2 Isosorbide glyceryl ether derivatives and their use in household applications
Disclosed are isosorbide glyceryl ether derivatives according to the following general formula (I), wherein R or R′ represent a hydrogen atom, or an alkyl or an acyl group with 6 to 22 C-atoms, and n and m represent independent from each other zero, or a number from 1 to 4, and the use thereof in cleansers or detergents or personal care applications.
US08420587B2 Liquid acidic hard surface cleaning composition
Liquid compositions for cleaning hard-surfaces having pH comprised between 3 and 4, obtained upon the mixing of an acid agent having a pKa comprised between 4 and 6, a source of alkalinity and a surfactant system. Process for treating hard surfaces, preferably delicate, hard surfaces, by applying said composition onto said hard surface and the use of said composition for cleaning hard surface while maintaining surface safety.
US08420584B2 Enzymatic detergent
A non-toxic enzymatic detergent for use in cleaning surgical instruments and the like which have a large build-up of bio-residue thereon and which need specialty cleaning in order to avoid both hardened bio-residue and certain fluid traces from the instruments for both operating accuracy as well as sterilization requirements.
US08420583B2 Olefin copolymer dispersant VI improver and lubricant compositions and uses thereof
A lubricating oil composition and methods of operating an internal combustion engine to provide improved engine operation. The lubricating composition includes a major amount of oil of lubricating viscosity; and a minor amount of at least one highly grafted, multi-functional olefin copolymer made by reacting an acylating agent with an olefin copolymer having a number average molecular weight greater than about 10,000 up to about 50,000 in the presence of a free radical initiator to provide an acylated olefin copolymer having a degree of grafting (DOG) of the acylating agent on the olefin copolymer of from above about 1.5 to about 3.0 wt. %. The acylated olefin copolymer is then reacted with an amine to provide the highly grafted, multi-functional olefin copolymer.
US08420581B2 Threaded joint for pipes having a lubricating coating
A lubricating coating which is free from harmful heavy metals is formed on a premium threaded joint for pipes constituted by a pin and a box each having a contact surface comprising a threaded portion and an unthreaded metal contact portion (a sealing surface and shoulder) in order to provide the joint with galling resistance, gas-tightness, and anticorrosive properties such that the unthreaded metal contact portion is prevented from yielding even when the joint is made up with a high torque. The lubricating coating comprises one or both of a rosin and calcium fluoride; metal soap; wax; and a basic metal salt of an aromatic organic acid, and preferably it further includes a lubricating powder, magnesium carbonate, and/or a carbohydrate, particularly a cyclodextrin.
US08420578B2 Low-density ceramic proppant and its production method
A low-density ceramic proppant is formed from a light aggregate of a natural mineral and a ceramic binding material in the form of a proppant granule. The light aggregate expands in volume when burnt so that the density of the aggregate is changed. A method of preparing a proppant material is carried out by pre-crushing and pre-mixing of raw components. This is followed by their granulation into proppant granules, drying and screening of the granules to a selected size. The raw components include at least a ceramic binding material and a light aggregate of a natural mineral that, when burnt, expands in volume so that the specific volume of the aggregate is changed. The burning of the light aggregate may be accomplished before or after the aggregate is mixed with the binding material.
US08420569B2 Pesticidal mixtures
Pesticidal mixtures comprising, as active components, 1) an anthranilamid compound of the formula I wherein the variables are defined according to the description, and 2) at least one fungicidal compound II selected from the following groups: strobilurins, carboxamides, heterocylic compounds and other active compounds according to the description, in a synergistically effective amount, methods for controlling pests, and harmful fungi, methods of protecting plants from attack or infestation by insects, acarids or nematodes, methods for treating, controlling, preventing or protecting an animal against infestation or infection by parasites, compositions containing these mixtures, and methods for their preparation.
US08420565B2 Hydroprocessing bulk catalyst and methods of making thereof
A hydroprocessing bulk catalyst is provided. A process to prepare hydroprocessing bulk catalysts is also provided. The hydroprocessing catalyst has the formula (Rp)i(Mt)a(Lu)b(Sv)d(Cw)e(Hx)f(Oy)g(Nz)h, wherein M is at least at least a “d” block element metal; L is also at least a “d” block element metal, but different from M; t, u, v, w, x, y, z representing the total charge for each of the components (M, L, S, C, H, O and N, respectively); R is optional and in one embodiment, R is a lanthanoid element metal; 0<=i<=1; pi+ta+ub+vd+we+xf+yg+zh=0; 0
US08420562B2 Process for the preparation of an unsupported, solid metallocene catalyst system and its use in polymerization of olefins
Improved process for the preparation of an unsupported, heterogeneous olefin polymerization catalyst system, comprising an organometallic compound of a transition metal of Group 3 to 10 of the Periodic Table (IUPAC) or of an actinide or lanthanide in the form of solid particles comprising the steps of a) preparing a solution of catalyst components, including an aluminoxane, a compound being effective to form stable, liquid clathrates with aluminoxane and an organometallic compound of a transition metal of Group 3 to 10 of the Periodic Table (IUPAC 2007) or of an actinide or lanthanide, in a hydrocarbon solvent, yielding a two phase system with an upper solvent layer, which is separated, b) preparing a liquid/liquid emulsion system comprising a continuous phase in which said solution of the catalyst components forms a dispersed phase in the form of droplets, c) solidifying said dispersed phase to convert said droplets to solid particles and optionally recovering said particles to obtain said catalyst system, the catalysts system itself and its use for olefin polymerization.
US08420556B2 High strength, durable micro and nano-fiber fabrics produced by fibrillating bicomponent islands in the sea fibers
The subject matter disclosed herein relates generally to fabrics composed of micro-denier fibers wherein said fibers are formed as bicomponent fibrillated fiber. The energy is sufficient for fibrillating as well as entangling (bonding) the fibers. These fabrics can be woven or knitted and made from made from bicomponent islands in the sea fibers and filaments or can be nonwovens and formed by either spunbonding or through the use of bicomponent staple fibers formed into a web by any one of several means and bonded similarly to those used for the spunbonded filament webs.
US08420554B2 Wafer support ring
A wafer support ring and a method of using the same are disclosed herein. The support ring supports a wafer during a first processing operation. A top surface of the support ring is in contact with a first plurality of locations on a surface of the wafer during the first processing operation. A second wafer support structure is used to support the wafer during a second processing operation. A top surface of the second wafer support structure is in contact with a second, different plurality of locations on the surface of the wafer during the second processing operation. The wafer support ring may also have an outer lip disposed about an outer periphery of the support ring that has a depth such that it does not form part of the top surface of the support ring.
US08420553B2 Semiconductor device and manufacturing method thereof
A manufacturing method of a semiconductor device, which includes the steps of forming a gate electrode layer over a substrate having an insulating surface, forming a gate insulating layer over the gate electrode layer, forming an oxide semiconductor layer over the gate insulating layer, forming a source electrode layer and a drain electrode layer over the oxide semiconductor layer, forming an insulating layer including oxygen over the oxide semiconductor layer, the source electrode layer, and the drain electrode layer, and after formation of an insulating layer including hydrogen over the insulating layer including oxygen, performing heat treatment so that hydrogen in the insulating layer including hydrogen is supplied to at least the oxide semiconductor layer.
US08420551B2 Methods of fabricating semiconductor devices and semiconductor devices fabricated by the same
Example methods and example embodiments include methods of fabricating semiconductor devices and semiconductor devices fabricated by the same. Example fabricating methods include forming a first nanowire, oxidizing the first nanowire to form a first nanostructure including a first insulator and a second nanowire, and oxidizing the second nanowire to form a second nanostructure including a second insulator and nanodots. Example semiconductor devices include nanostructures including nanodots and nanostructures providing storage nodes in memory devices.
US08420543B1 Method for treating the dislocation in a GaN-containing semiconductor layer
A method for treating the threading dislocation within a GaN-containing semiconductor layer is provided. The method includes a substrate is provided. A GaN-containing semiconductor layer with the threading dislocation is formed on the substrate. An etching process with an etching gas is performed to remove the threading dislocation in the GaN-containing semiconductor layer so as to increase the efficiency for the light emitting device.
US08420540B2 Sub-lithographic printing method
A trench structure and an integrated circuit comprising sub-lithographic trench structures in a substrate. In one embodiment the trench structure is created by forming sets of trenches with a lithographic mask and filling the sets of trenches with sets of step spacer blocks comprising two alternating spacer materials which are separately removable from each other. In one embodiment, the trench structures formed are one-nth the thickness of the lithographic mask's feature size. The size of the trench structures being dependent on the thickness and number of spacer material layers used to form the set of step spacer blocks. The number of spacer material layers being n/2 and the thickness of each spacer material layer being one-nth of the lithographic mask's feature size.
US08420539B2 Additive for polishing composition
The invention relates to an additive for polishing composition, which can ensure stable polishing properties. The additive for polishing composition contains one or more amine compounds and an alcohol. The one or more amine compounds contain a quaternary ammonium salt. When the one or more amine compounds are contained in high concentration, the occurrence of precipitation of the amine compound can be prevented by including the alcohol.
US08420535B2 Copper interconnection, method for forming copper interconnection structure, and semiconductor device
A copper interconnection structure includes an insulating layer, an interconnection body including copper and a barrier layer surrounding the interconnection body. The barrier layer includes a first barrier layer formed between a first portion of the interconnection body and the insulating layer. The first portion of the interconnection body is part of the interconnection body that faces the insulating layer. The barrier layer also includes a second barrier layer formed on a second portion of the interconnection body. The second portion of the interconnection body is part of the interconnection body not facing the insulating layer. Each of the first and the second barrier layers is formed of an oxide layer including manganese, and each of the first and the second barrier layers has a position where the atomic concentration of manganese is maximized in their thickness direction of the first and the second barrier layers.
US08420533B2 Metallization system of a semiconductor device comprising rounded interconnects formed by hard mask rounding
In sophisticated metallization systems, vertical contacts and metal lines may be formed on the basis of a dual inlaid strategy, wherein an edge rounding or corner rounding may be applied to the trench hard mask prior to forming the via openings on the basis of a self-aligned via trench concept. Consequently, self-aligned interconnect structures may be obtained, while at the same time providing superior fill conditions during the deposition of barrier materials and conductive fill materials.
US08420527B2 Semiconductor integrated circuit device
Interconnections are formed over an interlayer insulating film which covers MISFETQ1 formed on the principal surface of a semiconductor substrate, while dummy interconnections are disposed in a region spaced from such interconnections. Dummy interconnections are disposed also in a scribing area. Dummy interconnections are not formed at the peripheries of a bonding pad and a marker. In addition, a gate electrode of a MISFET and a dummy gate interconnection formed of the same layer are disposed. Furthermore, dummy regions are disposed in a shallow trench element-isolation region. After such dummy members are disposed, an insulating film is planarized by the CMP method.
US08420520B2 Non-cyanide gold electroplating for fine-line gold traces and gold pads
The present invention provides a method for fabricating chip package comprises the following steps: forming a photoresist layer on a metal layer over a passivation layer, an opening in the photoresist layer exposing the metal layer, wherein said forming the photoresist layer comprises exposing the photoresist layer using 1X stepper with at least two of G-line, H-line and I-line; electroplating a gold layer over the metal layer exposed by the opening with an electroplating solution containing gold and sulfite ion; removing the photoresist layer and the metal layer not under the gold layer.
US08420517B2 Methods of forming a multi-doped junction with silicon-containing particles
A method of forming a multi-doped junction on a substrate is disclosed. The method includes providing the substrate doped with boron atoms, the substrate comprising a front substrate surface. The method further includes depositing an ink on the front substrate surface in a ink pattern, the ink comprising a set of silicon-containing particles and a set of solvents. The method also includes heating the substrate in a baking ambient to a first temperature and for a first time period in order to create a densified film ink pattern. The method further includes exposing the substrate to a dopant source in a diffusion furnace with a deposition ambient, the deposition ambient comprising POCl3, a carrier N2 gas, a main N2 gas, and a reactive O2 gas at a second temperature and for a second time period, wherein a PSG layer is formed on the front substrate surface and on the densified film ink pattern; and heating the substrate in a drive-in ambient to a third temperature; wherein a first diffused region with a first sheet resistance is formed under the front substrate surface covered by the densified film ink pattern, and a second diffused region with a second sheet resistance is formed under the front substrate surface not covered with the densified film ink pattern, and wherein the first sheet resistance is substantially smaller than the second sheet resistance.
US08420514B2 Epitaxial silicon wafer and method for manufacturing same
It is an object to provide an epitaxial silicon wafer that is provided with an excellent gettering ability in which a polysilicon layer is formed on the rear face side of a silicon crystal substrate into which phosphorus (P) and germanium (Ge) have been doped. A PBS forming step for growing a polysilicon layer is executed on the rear face side of a silicon crystal substrate into which phosphorus and germanium have been doped at a high concentration to execute a baking treatment. After a surface layer of the silicon crystal substrate is then polished up to a predetermined amount, a silicon epitaxial layer is grown by a CVD method. By the above steps, the number of LPDs (caused by an SF) that occur on the surface of the epitaxial silicon wafer due to the SF can be greatly reduced.
US08420512B2 Method for manufacturing semiconductor device
A method for manufacturing a semiconductor device according to the invention irradiates a first pulse laser beam with an irradiation energy density of 1.0 J/cm2 or higher to blow off particles on the surface of wafer in activating an impurity layer positioned at a shallow location from the surface of wafer such as p+-type collector layer in an FS-type IGBT or in an NPT-type IGBT. By irradiating a second laser beam, region, on which particles were, is activated in the same manner as the region, on which particles are not, and p+-type collector layer is formed uniformly. The manufacturing method according to the invention facilitates preventing nonuniform laser beam irradiation from causing in laser annealing and preventing defective devices from causing.
US08420511B2 Transistor and method for forming the same
The invention provides a method for forming a transistor, which includes: providing a substrate, a semiconductor layer being formed on the substrate; forming a dummy gate structure on the semiconductor layer; forming a source region and a drain region in the substrate and the semiconductor layer and at opposite sides of the dummy gate structure; forming an interlayer dielectric layer on the semiconductor layer; removing the dummy gate structure for forming an opening in the interlayer dielectric layer; non-crystallizing the semiconductor layer exposed in the opening for forming a channel layer; annealing the channel layer so that the channel layer and the substrate have same crystal orientation; and forming a metal gate structure in the opening, the metal gate being formed on the channel layer. Saturation current of the transistor is raised, and the performance of a semiconductor device is promoted.
US08420510B2 Method of manufacturing semiconductor device
Provided is a method of manufacturing a semiconductor device wherein the space between semiconductor elements that are three-dimensionally mounted can be filled easily and securely. The method of manufacturing a semiconductor device of the present invention includes preparing a semiconductor wafer with a plurality of members for connection formed on both first and second surfaces; preparing a laminated film including a dicing sheet with a pressure-sensitive adhesive layer laminated on a base material, and a curable film that is laminated on the pressure-sensitive adhesive layer and has a thickness equivalent to or more than the height of the member for connection on the first surface; pasting the curable film of the laminated film to the semiconductor wafer while facing the curable film to the first surface so that the members for connection are not exposed to the pressure-sensitive adhesive layer; and dicing the semiconductor wafer to form a semiconductor element.
US08420505B2 Process for manufacture of thin wafer
A process to thin semiconductor wafers to less than 50 microns employs a dissolvable photoresist or polyimide or other glue material to hold a thick carrier plate such as a perforated glass to the top surface of a thick processed wafer and to grind or otherwise remove the bulk of the wafer from its rear surface, leaving only the preprocessed top surface, which may include semiconductor device diffusions and electrodes. A thick metal such as copper or a more brittle copper alloy is then conductively secured to the ground back surface and the glue is dissolved and the carrier plate is removed. The wafer is then cleaned and diced into plural devices such as MOSFETs; integrated circuits and the like.
US08420500B2 Method of producing a structure by layer transfer
The invention relates to a method of producing a semiconductor structure by transferring a layer of a donor substrate to a receiver substrate, with the creation of an embrittlement zone in the donor substrate to define the transfer layer, and the treatment of the surface of one of the substrates to increase the bonding strength between them, followed by the direct wafer bonding of the substrates and the detachment of the donor substrate at the embrittlement zone to form the semiconductor structure, in which the surface of the receiver substrate, except for a peripheral crown, is covered with the transferred layer. The treatment of the substrate surface is controlled so that the bonding strength between the substrates is lower in a peripheral area than in a central area. The peripheral area has a width at least equal to the that of the crown and less than 10 mm.
US08420497B2 Semiconductor structure and method of forming the semiconductor structure that provides two individual resistors or a capacitor
A semiconductor structure is formed in the metal interconnect structure of an integrated circuit in a method that provides either two individual resistors that are vertically isolated from each other, or a metal-insulator-metal (MIM) capacitor. As a result, both semiconductor resistors and MIM capacitors can be formed in the same process flow.
US08420496B2 Semiconductor device and method of fabricating the same
A PIN diode has an n− drift layer, a p anode layer, an n buffer layer, an n+ layer, a front surface electrode and a back surface electrode. The n+ layer has an impurity concentration having a stepwise profile substantially fixed for a predetermined depth measured from a second major surface. The n buffer layer has an impurity concentration gently decreasing as seen at the n+ layer toward n− drift layer. The n− drift layer has an impurity concentration reflecting that of the semiconductor substrate and thus substantially fixed depthwise. The p anode layer has an impurity concentration relatively steeply decreasing as seen at a first major surface toward the n− drift layer. Thus there can be provided a semiconductor device that can provide characteristics, as desired, with high precision to accommodate the product applied, and a method of fabricating the semiconductor device.
US08420493B2 SOI SiGe-base lateral bipolar junction transistor
A lateral heterojunction bipolar transistor (HBT) is formed on a semiconductor-on-insulator substrate. The HBT includes a base including a doped silicon-germanium alloy base region, an emitter including doped silicon and laterally contacting the base, and a collector including doped silicon and laterally contacting the base. Because the collector current is channeled through the doped silicon-germanium base region, the HBT can accommodate a greater current density than a comparable bipolar transistor employing a silicon channel. The base may also include an upper silicon base region and/or a lower silicon base region. In this case, the collector current is concentrated in the doped silicon-germanium base region, thereby minimizing noise introduced to carrier scattering at the periphery of the base. Further, parasitic capacitance is minimized because the emitter-base junction area is the same as the collector-base junction area.
US08420492B2 MOS transistor and method for forming the same
The invention provides a MOS transistor and a method for forming the MOS transistor. The MOS transistor includes a semiconductor substrate; a gate stack on the semiconductor substrate, and including a gate dielectric layer and a gate electrode on the semiconductor substrate in sequence; a source region and a drain region, respectively at sidewalls of the gate stack sidewalls of the gate stack and in the semiconductor; sacrificial metal spacers on sidewalls of the gate stack sidewalls of the gate stack, and having tensile stress or compressive stress. This invention scales down the equivalent oxide thickness, improves uniformity of device performance, raises carrier mobility and promotes device performance.
US08420488B2 Method of fabricating high voltage device
A high voltage device is provided. The high voltage device includes a gate on a substrate, two source/drain regions in the substrate beside the gate, and a composite gate dielectric layer that includes at least two stacked continuous layers, extending from one side to another side of the gate. Wherein, the at least two stacked continuous layers is a combination of at least one thermal oxide layer and at least one chemical vapor deposited layer.
US08420486B2 Method for manufacturing semiconductor device
In the present invention, there is provided a method for manufacturing a semiconductor device that has on a semiconductor substrate first and second transistor groups having different operating voltages respectively, the first transistor group having a first gate electrode, the second transistor group having a second gate electrode, the method including the steps of: forming the silicide layer on the first gate electrode of the first transistor group after setting a height of the first gate electrode smaller than a height of a dummy gate electrode formed in a dummy gate part; and forming a gate forming trench by removing the dummy gate part after forming an interlayer insulating film that covers a silicide layer and planarizing a surface of the interlayer insulating film.
US08420485B2 Semiconductor device having vertical channel transistor and method of manufacturing the same
A semiconductor device and method of manufacturing the same. The method includes: defining a first active area and a second active area on a substrate, the first and second active areas being in a line form, forming a first main trench and a second main trench on the substrate, forming a first sub-trench and a second sub-trench in bottoms of the first and second main trenches, respectively, forming a buried insulation layer filling the first and second sub-trenches, partially exposing the substrate at an area where the first active area crosses with the first sub-trench and an area where the second active area crosses with the second sub-trench and forming the first buried bit line and the second buried bit line on the buried insulation layer, and the first and second buried bit lines being extended in parallel to each other.
US08420482B2 Nonvolatile memory device and method of forming the same
A nonvolatile memory device and a method of forming the nonvolatile memory device, the method including forming a tunnel insulating layer on a substrate, wherein forming the tunnel insulating layer includes forming a multi-element insulating layer by a process including sequentially supplying a first element source, a second element source, and a third element source to the substrate, forming a charge storage layer on the tunnel insulating layer, forming a blocking insulating layer on the charge storage layer, and forming a control gate electrode on the blocking insulating layer.
US08420481B2 Memory cell device and method of manufacture
According to one embodiment of the present invention, a solid state electrolyte memory cell includes a cathode, an anode and a solid state electrolyte. The anode includes an intercalating material and first metal species dispersed in the intercalating material.
US08420478B2 Controlled localized defect paths for resistive memories
Controlled localized defect paths for resistive memories are described, including a method for forming controlled localized defect paths including forming a first electrode forming a metal oxide layer on the first electrode, masking the metal oxide to create exposed regions and concealed regions of a surface of the metal oxide, and altering the exposed regions of the metal oxide to create localized defect paths beneath the exposed regions.
US08420468B2 Strain-compensated field effect transistor and associated method of forming the transistor
Disclosed are embodiments of a field effect transistor (FET) having decreased drive current temperature sensitivity. Specifically, any temperature-dependent carrier mobility change in the FET channel region is simultaneously counteracted by an opposite strain-dependent carrier mobility change to ensure that drive current remains approximately constant or at least within a predetermined range in response to temperature variations. This opposite strain-dependent carrier mobility change is provided by a straining structure that is configured to impart a temperature-dependent amount of a pre-selected strain type on the channel region. Also disclosed are embodiments of an associated method of forming the field effect transistor.
US08420464B2 Spacer as hard mask scheme for in-situ doping in CMOS finFETs
A method of fabricating a semiconductor device that includes at least two fin structures, wherein one of the at least two fin structures include epitaxially formed in-situ doped second source and drain regions having a facetted exterior sidewall that are present on the sidewalls of the fin structure. In another embodiment, the disclosure also provides a method of fabricating a finFET that includes forming a recess in a sidewall of a fin structure, and epitaxially forming an extension dopant region in the recess that is formed in the fin structure. Structures formed by the aforementioned methods are also described.
US08420462B2 Display device and manufacturing method thereof
A display device including a thin film transistor with high electric characteristics and high reliability, and a method for manufacturing the display device in high yield are proposed. In a display device including a channel stop thin film transistor with an inverted-staggered structure, the channel stop thin film transistor with the inverted-staggered structure includes a microcrystalline semiconductor film including a channel formation region. An impurity region including an impurity element imparting one conductivity type is formed as selected in a region in the channel formation region of the microcrystalline semiconductor film which does not overlap with a source electrode or a drain electrode. In the channel formation region, a non-doped region, to which the impurity element imparting one conductivity type is not added, is formed between the impurity region, which is a doped region to which the impurity element is added, and the source region or the drain region.
US08420457B2 Thin film transistor and method of manufacturing the same
A thin film transistor, including a transparent channel pattern, a transparent gate insulating layer in contact with the channel pattern, a passivation film pattern disposed on the channel pattern, a source/drain coupled to the channel pattern through a via hole in the passivation film pattern, and a gate facing the channel pattern, the gate insulating layer interposed between the gate and the channel pattern, wherein the passivation film pattern includes at least one of polyimide, photoacryl, and spin on glass (SOG).
US08420456B2 Method of manufacturing for thin film transistor
An object is to provide a semiconductor device with improved reliability in which a defect stemming from an end portion of a semiconductor layer provided in an island shape is prevented, and a manufacturing method thereof. Over a substrate having an insulating surface, an island-shaped semiconductor layer is formed, a first alteration treatment is performed, a first insulating film is formed on a surface of the island-shaped semiconductor layer, the first insulating film is removed, a second alteration treatment is performed on the island-shaped semiconductor from which the first insulating film is removed, a second insulating film is formed on a surface of the island-shaped semiconductor layer, and a conductive layer is formed over the second insulating film. An upper end portion of the island-shaped semiconductor layer has curvature by the first alteration treatment and the second alteration treatment.
US08420454B2 Three-terminal power device with high switching speed and manufacturing process
An embodiment of a power device having a first current-conduction terminal, a second current-conduction terminal, a control terminal receiving, in use, a control voltage of the power device, and a thyristor device and a first insulated-gate switch device coupled in series between the first and the second conduction terminals; the first insulated-gate switch device has a gate terminal coupled to the control terminal, and the thyristor device has a base terminal. The power device is further provided with: a second insulated-gate switch device, coupled between the first current-conduction terminal and the base terminal of the thyristor device, and having a respective gate terminal coupled to the control terminal; and a Zener diode, coupled between the base terminal of the thyristor device and the second current-conduction terminal so as to enable extraction of current from the base terminal in a given operating condition.
US08420453B2 Method of forming active region structure
A method of forming an active region structure includes preparing a semiconductor substrate including a cell array region and a peripheral circuit region, forming preliminary cell active regions in the cell array region of the semiconductor substrate, and forming cell active regions in the preliminary cell active regions and at least one peripheral active region in the peripheral circuit region of the semiconductor substrate, such that the preliminary cell active regions, the cell active regions, and the at least one peripheral active region are integrally formed with the semiconductor substrate and protrude from the semiconductor substrate.
US08420452B2 Fabrication method of leadframe-based semiconductor package
A leadframe-based semiconductor package and a fabrication method thereof are provided. The leadframe-based semiconductor package includes a chip implanted with a plurality of first and second conductive bumps thereon, and a leadframe having a plurality of leads. The first conductive bumps are bonded to the leads to electrically connect the chip to the leadframe. The chip, the first and second conductive bumps, and the leadframe are encapsulated by an encapsulant, with bottom ends of the second conductive bumps and bottom surfaces of the leads being exposed from the encapsulant. This allows the second conductive bumps to provide additional input/output electrical connections for the chip besides the leads.
US08420450B2 Method of molding semiconductor package
A method of molding a semiconductor package includes coating liquid molding resin or disposing solid molding resin on a top surface of a semiconductor chip arranged on a substrate. The solid molding resin may include powdered molding resin or sheet-type molding resin. In a case where liquid molding resin is coated on the top surface of the semiconductor chip, the substrate is mounted between a lower molding and an upper molding, and then melted molding resin is filled in a space between the lower molding and the upper molding. In a case where the solid molding resin is disposed on the top surface of the semiconductor chip, the substrate is mounted on a lower mold and then the solid molding resin is heated and melts into liquid molding resin having flowability. An upper mold is mounted on the lower mold, and melted molding resin is filled in a space between the lower molding and the upper molding.
US08420449B2 Laser patterning apparatus and laser patterning method
Aspects of the invention are directed to laser patterning apparatus capable of performing laser patterning on a thin film formed on a flexible substrate with a good yield and a laser patterning method thereof. The thin film formed on the flexible substrate can be patterned by laser using a laser patterning apparatus that can include a processing stage that has a reference processing surface on which the flexible substrate having the thin film formed thereon is disposed, a wrinkle removing device that is configured as a mechanism for stretching an outer periphery of a processing region of the flexible substrate so that tension is applied outward in the width direction and forward and backward in the transporting direction, and a laser scanner that scans a predetermined line of the thin film formed on the flexible substrate while emitting a laser beam thereto.
US08420448B2 Integrated circuit packaging system with pads and method of manufacture thereof
A method of manufacture of an integrated circuit packaging system includes: providing a lead frame having a frame platform and a frame base; forming an elevated paddle on the frame platform and a base pad on the frame base; mounting an integrated circuit over the elevated paddle; forming an encapsulation on the lead frame and over the elevated paddle, the base pad, the integrated circuit, and the internal interconnect; and removing the lead frame to expose an encapsulation recess and an encapsulation base with the base pad exposed along the encapsulation base and the elevated paddle exposed in the encapsulation recess.
US08420444B2 Semiconductor device and method of manufacturing the same
A semiconductor device includes a first bump that is located over a surface of a semiconductor element, and is formed on a first bump formation face distanced from a back surface of the semiconductor element at a first distance, and a second bump that is located over the surface of the semiconductor element, and is formed on a second bump formation face distanced from the back surface of the semiconductor element at a second distance being longer than the first distance, the second bump having a diameter larger than a diameter of the first bump.
US08420439B2 Method of producing a radiation-emitting thin film component and radiation-emitting thin film component
A method of producing a radiation-emitting thin film component includes providing a substrate, growing nanorods on the substrate, growing a semiconductor layer sequence with at least one active layer epitaxially on the nanorods, applying a carrier to the semiconductor layer sequence, and detaching the semiconductor layer sequence and the carrier from the substrate by at least partial destruction of the nanorods.
US08420437B1 Method for forming an EMI shielding layer on all surfaces of a semiconductor package
Disclosed is a method for forming an EMI shielding layer on all surfaces of a semiconductor package in order to enhance EMI shielding effect on all surfaces and to prevent electrical short to external terminals of the semiconductor package. According to the method, a temporary protective layer is formed on the external terminals where the temporary protective layer is further in contact with a plurality of annular surface regions of the semiconductor package surrounding and adjacent to the external terminals. Then, the EMI shielding layer is formed on the top surface, the bottom surface and the side surfaces of the semiconductor package without forming on the external terminals.
US08420436B2 Method for manufacturing solar cell, etching device, and CVD device
A solar cell manufacturing method according to the present invention is a solar cell manufacturing method that forms a transparent conductive film of ZnO as an electric power extracting electrode on a light incident side, the method comprises at least in a following order: a process A forming the transparent conductive film on a substrate by applying a sputtering voltage to sputter a target made of a film formation material for the transparent conductive film; a process B forming a texture on a surface of the transparent conductive film; a process C cleaning the surface of the transparent conductive film on which the texture has been formed using an UV/ozone; and a process D forming an electric power generation layer on the transparent conductive film.
US08420430B2 Fabrication method of package structure having MEMS element
A fabrication method of a package structure having at least an MEMS element is provided, including: preparing a wafer having electrical connection pads and the at least an MEMS element; disposing lids for covering the at least an MEMS element, the lids having a metal layer formed thereon; electrically connecting the electrical connection pads and the metal layer with bonding wires; forming an encapsulant for covering the lids, bonding wires, electrical connection pads and metal layer; removing portions of the encapsulant to separate the bonding wires each into first and second sub-bonding wires, wherein top ends of the first and second sub-bonding wires are exposed, the first sub-bonding wires electrically connecting to the electrical connection pads, and the second sub-bonding wires electrically connecting to the metal layer; forming metallic traces on the encapsulant for electrically connecting to the first sub-bonding wires; forming bumps on the metallic traces; and performing a singulation process.
US08420428B2 Method for forming buried cavities within a semiconductor body, and semiconductor body thus made
A method for the formation of buried cavities within a semiconductor body envisages the steps of: providing a wafer having a bulk region made of semiconductor material; digging, in the bulk region, trenches delimiting between them walls of semiconductor material; forming a closing layer for closing the trenches in the presence of a deoxidizing atmosphere so as to englobe the deoxidizing atmosphere within the trenches; and carrying out a thermal treatment such as to cause migration of the semiconductor material of the walls and to form a buried cavity. Furthermore, before the thermal treatment is carried out, a barrier layer that is substantially impermeable to hydrogen is formed on the closing layer on top of the trenches.
US08420426B2 Method of manufacturing a light-emitting device
To provide a light-emitting device using a nitride semiconductor which can attain high-power light emission by highly efficient light emission, a method of manufacturing the light-emitting device involves forming a first AlGaN layer of a first conductivity type on a side of a first main surface of a nitride semiconductor substrate, forming a light-emitting layer including an InAlGaN quaternary alloy on the first AlGaN layer, forming a second AlGaN layer of a second conductivity type on the light-emitting layer, and removing the nitride semiconductor substrate after forming the second AlGaN layer.
US08420422B2 Pattern forming method, processing method, and processing apparatus
According to the embodiments, a distribution of a recess portion shape is calculated based on a result obtained by measuring the recess portion shape of a first projection and recess pattern formed on a surface of a template. Next, a distribution of an application amount of a curing agent to a processing target layer is calculated based on the distribution of the recess portion shape, and the curing agent is applied to the processing target layer based on this distribution of the application amount of the curing agent. Next, a second projection and recess pattern is formed by transferring the first projection and recess pattern onto the curing agent by causing the curing agent to cure in a state where the first projection and recess pattern is in contact with the curing agent.
US08420415B2 Method for forming a light conversion material
A method and system for manufacturing a light conversion structure for a light emitting diode (LED) is disclosed. The method includes forming a transparent, thermally insulating cover over an LED chip. The method also includes dispensing a conversion material onto the cover to form a conversion coating on the cover, and encapsulating the LED, the silicone cover, and the conversion coating within an encapsulant. Additional covers and conversion coatings can be added.
US08420414B2 Method of manufacturing light-emitting device
A method of manufacturing a light-emitting device includes forming a planar board that includes a plurality of first metallic plates and a plurality of second metallic plates continuously connected by a resin, by use of a positioning frame including a plurality of first concave portions and a plurality of second concave portions, mounting a plurality of light-emitting diode elements on the planar board, and sealing the light-emitting diode elements collectively, thereby producing a plurality of light-emitting devices.
US08420401B2 Glucose tolerance test device
A glucose tolerance test device comprising: a test zone having a means to receive at least first and second blood test samples spaced apart by a predetermined time interval; a timer to measure such a time interval, and for example to measure elapsed time after collection of a said first sample; an indicator to indicate at least that a second test is due, operatively Jinked to the timer so as to make such indication after lapse of a predetermined time interval; a data collector to collect data from the lest zone in relation to each test sample; a data register to store data in relation to each test sample, in data communication with said data collector. A method of use is also described.
US08420400B2 System and method for authenticating tablets
A method for authenticating and verifying a pharmaceutical item to be genuine is described. The method for authenticating a tablet comprises applying a particular nucleic acid material associated with a particular sequence of nucleic acid bases to a tablet or capsule. The method also comprises collecting a sample of the tablet and verifying the tablet is genuine by detecting the particular nucleic acid material.
US08420399B2 Analytical method of hemoglobin
A method for analyzing hemoglobin in a sample by separation analysis while suppressing the denaturation of the hemoglobin includes separating hemoglobin in the presence of at least one of a sulfurous acid compound and a dithionous acid compound.
US08420398B2 Estrous cycle monitoring by color response
A method of determining the phase of an estrous cycle that a mammal is in at a given time that a biological sample is obtained from the mammal is provided. The biological sample obtained from the mammal is combined with at least one flavonoid pigment that reacts with the biological sample on a hydrophobic surface to provide a color response. The estrus phase of the estrous cycle has a corresponding color response that is distinguishable from the color response of each other phase of the estrous cycle to an unaided human eye. The corresponding color response is correlated to the estrus phase of the estrous cycle.
US08420397B2 Fluid flow device and assembly employing a temperature gadient for determining at least one characteristic of a physico-chemical system therewith
Fluid flow devices include a small plate (2), at least one flow channel (20) formed into this small plate, at least one storage channel (221-226) extending from this connection channel, and a set of valves (V1-V6), each of which is suitable for allowing or stopping the flow of fluid in a corresponding storage channel.
US08420387B2 Intein-modified enzymes, their production and industrial applications
A method of predicting an intein insertion site in a protein that will lead to a switching phenotype is provided. The method includes identifying a plurality of C/T/S sites within the protein; selecting from the plurality of C/T/S/ sites those that are ranked 0.75 or higher by a support vector machine, within ten angstroms of the active site of the protein, and at or near a loop-β-sheet junction or a loop-α-helix junction. A method of controlling protein activity and hosts including proteins with controlled activity are also provided. Also, intein modified proteins and plants containing intein modified proteins are provided.
US08420385B2 Collection device and material
Swabs, and materials of the present disclosure, and methods of making same, include randomly arranged sea-island bicomponent fibers.
US08420378B2 DNA encoding protein and methods of using same
The present invention relates to novel tools for improving MPA production. In particular, the present invention relates to fungal enzymes that are specific for MPA synthesis.
US08420373B2 Permissive cells and uses thereof
The invention relates generally to the field of virology. More particularly, the present invention relates to methods for determining the permissiveness of a cell for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The invention further provides methods and compositions related to the generation of host cells permissive for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Methods of using said cells thus identified or thus generated, in preparing a culture of a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, as well as the use of said virus for the purpose of vaccine production or diagnosis, are also provide by the present invention.
US08420369B2 Polypeptide having phytase activity and increased temperature resistance of the enzyme activity, and nucleotide sequence coding said polypeptide
The invention relates to a recombinant DNA molecule encoding a polypeptide having phytase activity and increased temperature stability and increased proteolytic stability of the enzyme activity. The DNA sequence has been obtained by variation of the mature wild-type E. coli phytase sequence with defined amino acid positions being modified in comparison to the wild-type sequence or with the sequences having N- and/or C-terminal extensions, respectively. The invention further relates to a method for expressing the recombinant phytase as well as its use in the food and animal feed technologies.
US08420366B2 Generation of modified polymerases for improved accuracy in single molecule sequencing
Provided are compositions comprising recombinant DNA polymerases that include amino acid substitutions, insertions, deletions and/or heterologous or exogenous features that confer modified properties upon the polymerase for enhanced single molecule sequencing. Such properties can include reduced reaction rates at one or more steps of the polymerase kinetic cycle, increased closed polymerase/DNA complex stability, enhanced metal ion coordination, reduced exonuclease activity, decreased branching fractions, and the like. Polymerases that exhibit branching fractions that are less than the branching fractions of the polymerases from which they were derived, or branching fractions that are less than about 25% for a phosphate-labeled nucleotide analog, are also provided. Also provided are nucleic acids which encode the polymerases with the aforementioned phenotypes, as well as methods of using such polymerases to make a DNA or to sequence a DNA template.
US08420365B2 11βhydroxysteroid dehydrogenase type 1
The invention provides gene-targeted non-human animals comprising a genetically modified 11βHSD1 gene encodes a mutant 11βHSD1 polypeptide which is modulated by human 11βHSD1 modulating compounds. The invention further provides cells expressing mutant 11βHSD1 and cells isolated from gene-targeted animals, which cells produce a mutant 11βHSD1. The invention further provides methods of identifying agents that modulate 11βHSD1 activity, and are useful to treat 11βHSD1-related metabolic disorders.
US08420364B2 Highly stable beta-class carbonic anhydrases useful in carbon capture systems
The present disclosure relates to β-class carbonic anhydrase polypeptides having improved properties including increased thermostability and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides formulations and uses of the polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. Also provided are polynucleotides encoding the carbonic anhydrase polypeptides and host cells capable of expressing them.
US08420362B2 In situ precipitation of calcium carbonate (CaCO3) by indigenous microorganisms to improve mechanical properties of a geomaterial
A method for increasing the concentration of calcium carbonate in a geomaterial that contains indigenous microorganisms capable of hydrolyzing urea to ammonia, which method includes enriching the geomaterial with a source of nutrients, adding urea to the geomaterial which is hydrolyzed to ammonia and which raises the pH of the geomaterial, and adding a source of calcium ions to the geomaterial. Carbonate ions obtained by the hydrolysis of the urea combine with calcium ions to form calcium carbonate.
US08420360B2 Compositions and methods for producing isoprene free of C5 hydrocarbons under decoupling conditions and/or safe operating ranges
The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
US08420352B2 Protein delivery system to generate pluripotent stem (iPS) cells or tissue specific cells
A novel protein delivery system to generate induced pluripotent stem (iPS) cells is described. The delivery system comprises a construct with a receptor binding domain that recognizes a receptor in a somatic cell, a translocation domain that allows the transfer of an inducer into the cytosolic space, and a cargo bearing domain to which the inducer is attached and facilitates transfer of the inducer into the cell.
US08420351B2 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US08420350B2 Glycosylation-deficient hepatocyte growth factor
The invention provides a modified glycosylation-deficient HGF and a production method thereof. The glycosylation-deficient HGF is produced by introducing amino acid mutation(s) so that no glycosylation take place at at least one glycosylation site of hepatocyte growth factor.
US08420335B2 Inhibition of GASC1
The present invention provides a method of testing the ability of a test compound to bind to and optionally modulate the activity of a protein of the JMJD2 subfamily of Jumonji proteins. The method comprises incubating a test compound with a protein of the JMJD2 subfamily of Jumonji proteins, a co-factor of said protein and, optionally, a substrate for demethylation. The method of the invention can be used for screening large numbers of compounds to identify a group of compounds that are candidate compounds for clinical use for treatment of certain cancers especially prostate cancers. Other compounds that do not have activity in the screening assays can be eliminated from further consideration as candidate compounds. The method of the invention therefore has utility in the pharmaceutical industry.
US08420334B2 Method for detecting invasive microvesicles derived from tumor cells
The present application relates to the isolation and analysis of populations of microvesicles, such as populations of microvesicles that are shed by tumor cells and contain the protein ARF6. Invasive microvesicles from tumor cells contain a variety of specific proteins, including ARF6.
US08420332B2 Tumor endothelial marker 5-α molecules and uses thereof
The present invention provides Tumor Endothelial Marker 5α (TEM5α) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing TEM5α polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, or prevention of diseases, disorders, and conditions associated with TEM5α polypeptides.
US08420326B2 Method of evaluating performance of activation gas deactivating antigenic substance and apparatus for generating processed antigenic substance used as evaluation sample of the evaluating method
A method of evaluating performance of an activation gas deactivating an antigenic substance including the steps of causing the antigenic substance and the activation gas to react with each other, to obtain a processed antigenic substance, and causing an antibody against the antigenic substance with the processed antigenic substance to measure binding activity of the processed antigenic substance with the antibody is provided, whereby an evaluation method that can accurately and easily evaluate performance of an activation gas deactivating an antigenic substance is provided.
US08420324B2 Compositions and methods for cDNA synthesis
Methods for making cDNA molecules, for amplification of RNA by PCR and for preparation of cDNA libraries are provided. Kits for making cDNA molecules also are provided. Compositions are also provided comprising mixtures of reagents, including reverse transcriptases, buffers, cofactors and other components, suitable for immediate use in conversion of RNA into cDNA and RT PCR without dilution or addition of further components. These compositions are useful, alone or in the form of kits, for cDNA synthesis or nucleic acid amplification (e.g., by the Polymerase Chain Reaction) or for any procedure utilizing reverse transcriptases in a variety of research, medical, diagnostic, forensic and agricultural applications.
US08420323B2 Nucleic acid amplification method
An object to be achieved by the present invention is to provide a nucleic acid amplification method by which a nucleic acid can be amplified using oligonucleotide primers and DNA polymerase. The present invention provides a nucleic acid amplification method which comprises performing incubation of a reaction solution containing at least one type of deoxynucleotide triphosphate, at least one type of DNA polymerase, at least two types of oligonucleotide primer, and the nucleic acid fragment as a template so as to perform a polymerase reaction that initiates from the 3′ end of the primer and thus amplifying the nucleic acid fragment, wherein a tag sequence is added at the 5′ end of the first oligonucleotide primer, and the tag sequence is a nucleotide sequence on the template nucleic acid fragment which is present downstream of the sequence which is substantially complementary with the 3′ end region of the first oligonucleotide primer (a region where the first oligonucleotide is annealed to the template nucleic acid).
US08420322B2 Isolated nucleotide sequences responsible for the tomato high pigment-1 mutant phenotype (hp-1) and uses thereof
The present invention provides isolated nucleotide sequences responsible for the tomato high pigment 1 (hp-1) and high pigment 1w (hp-1w) phenotypes, wherein said sequences comprises an altered tomato DDB1 gene sequence or fragment thereof, wherein said the alteration in said altered sequence or fragment comprises an A-to-T transversion at nucleotide 931 of said DDB1 gene sequence in the case of hp-1 and a G-to-A transition at nucleotide 2392 of said DDB1 gene sequence in the case of hp-1w.
US08420321B2 Method for the identification of a risk for a thrombogenic disorder by determining the TAFI-Ile347 polymorphism
The present invention is directed to a method identifying a risk for a thrombogenic disorder including, without limitation, atrial fibrillation, stroke, prolonged intermitted neurological deficit (PRIND), transitory ischemic attack (TIA), atherosclerotic cerebrovascular disease (CVD) and/or coronary heart disease, as well as to a method for selecting patients with a risk for a thrombogenic disorder, to a method for identifying a pharmaceutical for the therapy or prophylaxis of a thrombogenic disorder as well as to a method for producing a medicament and a diagnostic by employing the TAFI-Ile347 polymorphism.
US08420316B2 Method for Columbidae gender identification, nucleotide sequence for Columbidae gender and nucleotide primer pair for Columbidae gender
The invention provides a method for Columbidae gender identification including: providing a DNA sample of a bird belonging to the Columbidae family; performing a polymerase chain reaction to the DNA sample with a first primer pair of a first primer designed within the region of the SEQ ID. NO.: 9 or a complementary sequence thereof and a P2 primer (SEQ ID. NO: 1) or a complementary sequence thereof, and a second primer pair of a second primer designed within the region of the SEQ ID NO.: 10 or a complementary sequence thereof and a P2 primer (SEQ ID. NO: 1) or a complementary sequence thereof; and determining gender by performing a melting curve analysis to a product from the polymerase chain reaction, wherein the result showing two peaks indicate a female gender and showing one peak indicate a male gender.
US08420315B2 Single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene
Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
US08420314B2 Method for detecting human papillomavirus mRNA
An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided.
US08420312B2 Genes associated with canine osteoarthritis and related methods and compositions
Described herein is a combination containing polynucleotide molecules that are differentially expressed in osteoarthritis. Also described are methods that may be used for diagnosis and prognosis of osteoarthritis, as well as methods that may be used to screen test substances for effectiveness in treatment modalities for osteoarthritis. Also described are devices and kits that may be used with the described methods.
US08420309B2 Method of screening compounds using CALHM (FAM26C)
Provided are methods of screening test compounds for the ability to alter calcium homeostasis in mammalian cells by experimentally determining if a compound affects CALHM1, CALHM2, or CALHM3 expression or activity. Additionally provided are methods of screening a test compound for the ability to inhibit ERK 1/2 phosphorylation in a mammalian cell. Further provided are methods of screening a test compound for the ability to inhibit amyloid-beta peptide accumulation in a mammalian cell or biological fluid, methods of screening for a test compound that may affect Alzheimer's disease and methods of determining the likelihood that a subject will be diagnosed with Alzheimer's disease. Also provided are isolated and purified mammalian CALHM proteins, vectors comprising a nucleic acid sequence encoding the CALHM1, CALHM2, and CALHM3 proteins, and mammalian cells transfected with the vectors. Additionally, methods of affecting Ca2+ levels in a mammalian cell are provided.
US08420308B2 Methods and kits for diagnosis of schizophrenia
The present invention provides methods and kits for the diagnosis of schizophrenia, which employ mitochondrial complex I as a peripheral biological marker for schizophrenia. In an embodiment of the invention, the present invention provides a method for diagnosing schizophrenia in a subject by determining the level of m-RNA or protein mitochondrial complex I subunits and its activity by determining the cellular basal respiration through complex I enzyme.
US08420306B2 Cell division marker
This application relates to a newly identified animal cell structure, the midbody scar. This structure is a remnant of the midbody that is retained by one daughter cell following cytokinesis and persists through multiple subsequent cell cycles. The midbody scar can be useful as a marker of dividing cells or of a cell's replicative age.
US08420305B2 Method and apparatus for generating periodic patterns by step-and-align interference lithography
The present invention provides a method and an apparatus for generating periodic patterns by step-and-align interference lithography, wherein at least two coherent light beams with a pattern are controlled to project onto a substrate to be exposed to form an interference-patterned region on the substrate. Thereafter, by means of moving the substrate or the light beams stepwisely, a patterned region with a large area can be formed on the substrate. According to the present invention, the optical path and exposure time may be shortened to reduce defect formation during lithographic processing and to improve the yield.
US08420304B2 Resist coating and developing apparatus, resist coating and developing method, resist-film processing apparatus, and resist-film processing method
The present invention provides a resist coating and developing apparatus, a resist coating and developing method, a resist-film processing apparatus, and a resist-film processing method, capable of reducing a line width roughness by planarizing a resist pattern. The resist coating and developing apparatus comprises: a resist-film forming part configured to coat a resist onto a substrate to form a resist film thereon; a resist developing part configured to develop the exposed resist film to obtain a patterned resist film; and a solvent-gas supply part configured to expose the resist film, which has been developed and patterned by the resist developing part, to a first solvent of a gaseous atmosphere having a solubility to the resist film. A solvent supply part supplies, to the resist film which has been exposed to the first solvent, a second solvent in a liquid state having a solubility to the resist film.
US08420301B2 Method for forming a wiring pattern by laser irradiation
A method for forming a wiring pattern by laser irradiation includes the steps of coating a light-sensitive material on a substrate to form a light-sensitive layer, irradiating a laser beam on the light-sensitive material of the substrate to form a pattern including an exposed region exposed to laser irradiation and an unexposed region unexposed to laser irradiation, and forming a metallic wiring pattern by immersing the substrate into a solution having a plurality of metallic nano-particles. The metallic nano-particles are easily bonded to the straighter molecular structure of the light-sensitive material in the exposed region for forming a conducting wiring pattern. The laser irradiation method has advantages such as high-power, high-density, high-directionality and monochromaticity, such that product quality can be effectively controlled. Moreover, the laser irradiated light-sensitive material can form a molecular structure that is easily bonded to the metallic particles. As a result, the chemical wastes are substantially reduced.
US08420300B2 Method of producing multilayer printed wiring board and photosensitive dry film used therefor
A method of producing a multilayer printed wiring board by attaching a photosensitive dry film onto an interlaminar resin insulating layer having a thin-film conductor layer and conducting a light exposure and development to form a plating resist and then forming a conductor circuit on a portion not forming the plating resist. The photosensitive dry film has a nitrogen-containing heterocyclic compound layer on a first surface thereof.
US08420297B2 Developers and method of coloring lithographic printing members
A color contrast image in imaged lithographic printing precursors can be obtained by contacting the imaged precursor with a coloration solution containing a colorless form of a photochromic compound. Residual amounts of this compound attached to the oleophilic surface of the imaged precursor can be changed to its colored form when exposed to UV light. The coloration solution can be an alkaline or acidic developer or an alkaline or acidic solution used separately after development. The coloration solution can also be a gum solution.
US08420295B2 Lithographic printing plate precursor
A lithographic printing plate precursor includes a support and a layer containing a polymer compound having at least one support-adsorbing group at a terminal of a main chain.
US08420294B2 Salt and photoresist composition comprising the same
The present invention provides a salt represented by the formula (I): wherein R1 and R2 independently each represent a C1-C6 alkyl group or R1 and R2 are bonded each other to form a C5-C20 aliphatic ring together with the carbon atom to which they are bonded, R3 and R4 independently each represent a fluorine atom or a C1-C6 perfluoroalkyl group, X1 represents a C1-C17 divalent saturated hydrocarbon group in which one or more —CH2— can be replaced by —O— or —CO— and which may be substituted with one or more fluorine atoms, and Z1+ represents an organic counter ion.
US08420293B2 Optical waveguides and methods thereof
Embodiments in accordance with the present invention provide waveguide structures and methods of forming such structures where core and laterally adjacent cladding regions are defined. Some embodiments of the present invention provide waveguide structures where core regions are collectively surrounded by laterally adjacent cladding regions and cladding layers and methods of forming such structures.
US08420290B2 Acetal compounds and their preparation, polymers, resist compositions and patterning process
An acetal compound of formula (1) is provided wherein R1 is H, methyl or trifluoromethyl, R2 is a monovalent C1-C10 hydrocarbon group, R3 and R4 are H or a monovalent C1-C10 hydrocarbon group, R2 and R3 may together form an aliphatic hydrocarbon ring, and X1 is a single bond or a divalent C1-C4 hydrocarbon group. A polymer comprising recurring units derived from the acetal compound is used as a base resin to formulate a resist composition which exhibits a high resolution when processed by micropatterning technology, especially ArF lithography.
US08420288B2 Resist pattern thickening material, method for forming resist pattern, semiconductor device and method for manufacturing the same
The present invention provides a resist pattern thickening material, which can utilize ArF excimer laser light; which, when applied over a resist pattern to be thickened, e.g., in form of lines and spaces pattern, can thicken the resist pattern to be thickened regardless of the size of the resist pattern to be thickened; and which is suited for forming a fine space pattern or the like, exceeding exposure limits. The present invention also provides a process for forming a resist pattern and a process for manufacturing a semiconductor device, wherein the resist pattern thickening material of the present invention is suitably utilized.
US08420285B2 Coated carrier regenerating method, developing cartridge containing two component developer containing toner and coated carrier regenerated by same coated carrier regenerating method, and image forming apparatus detachably provided with same developing cartridge
A coated carrier regenerating method in accordance with the present invention includes the step of: determining an amount of a worn-away coating resin of a used coated carrier. Accordingly, an amount of the coating resin layer to be supplemented, namely an amount of the coating resin with which the coating resin layer is to be supplementarily coated is found based on this amount of the worn-away coating resin, whereby the supplementary coating of the used coated carrier can be carried out with the coating resin in the amount thus determined. This allows regeneration of a coated carrier in which a coating resin has a uniform thickness, that is, a coating resin layer has a thickness which is unchanged from the thickness obtained before use of the coated carrier, without the need of completely removing the coating resin from the used coated carrier. According to the method of the present invention as mentioned above, it is possible to easily regenerate, in a shorter time and at a lower cost, a coated carrier in which a coating resin layer has a uniform thickness.
US08420284B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor
An electrophotographic photoreceptor, including an electroconductive substrate; a photosensitive layer, located overlying the electroconductive substrate; and an outermost layer comprising a convexity, wherein each of the outermost layer and the convexity includes a crosslinked body including a structural unit having a same charge transportable structure, and wherein the number of convexity having a height not less than ½×RzJIS is from 30 to 300 in a measurement length of 12 mm, wherein RzJIS is an average of ten-point mean roughness specified in JIS B0601 of 2001 and measured at least 4 random positions in an area the outermost layer is formed on, and wherein the height of the convexity is a distance from the deepest valley to a top of the convexity in the measurement length of 12 mm.
US08420278B2 Solid oxide fuel cell having a glass composite seal
A solid oxide fuel cell stack having a plurality of cassettes and a glass composite seal disposed between the sealing surfaces of adjacent cassettes, thereby joining the cassettes and providing a hermetic seal therebetween. The glass composite seal includes an alkaline earth aluminosilicate (AEAS) glass disposed about a viscous glass such that the AEAS glass retains the viscous glass in a predetermined position between the first and second sealing surfaces. The AEAS glass provides geometric stability to the glass composite seal to maintain the proper distance between the adjacent cassettes while the viscous glass provides for a compliant and self-healing seal. The glass composite seal may include fibers, powders, and/or beads of zirconium oxide, aluminum oxide, yttria-stabilized zirconia (YSZ), or mixtures thereof, to enhance the desirable properties of the glass composite seal.
US08420276B2 Catalyst layer and preparation process thereof, and membrane-electrode assembly and polymer electrolyte fuel cell using the catalyst layer
In a membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, at least one catalyst layer constituting the gas diffusion electrodes characterized in that the ion-conductive binder comprises a block copolymer having a particle size of 1 μm or less comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both polymer blocks phase separate from each other, polymer block (A) forms a continuous phase, and the contact parts of the block copolymer with catalyst particles are comprised of polymer block (A) having ion-conductive groups; a membrane-electrode assembly and a polymer electrolyte fuel cell.
US08420275B2 Composite membrane, fuel cell, and method for fabricating the composite membranes
Electro membrane assemblies are formed respectively in openings provided in a substrate. Each membrane electrode assembly is provided with an electrolyte membrane, an anode catalyst layer, and a cathode catalyst layer. A protective layer is provided on the substrate disposed between the adjacent anode catalyst layers. The other protective layer is provided on the substrate disposed between the adjacent cathode catalyst layers. The protective layer and the other protective layer preferably contain a resin whose number of C—F bonds is greater than that of the substrate.
US08420272B2 Fuel cell system control device
In order to reliably avoid freezing in the generation stop state during intermittent operation, in the control device of the present invention that controls a fuel cell system to operate intermittently by switching between the generation state and the generation stop state of a fuel cell, it is determined whether to stop the generation operation during intermittent operation based on at least the temperature of a specific component that contains moisture from among the components constituting the fuel cell system. A valve, a passage, or a humidifier arranged on a flow path for a fuel gas or oxidizing gas may be selected as the specific component mentioned above. The temperature of the specific component is measured either directly by a temperature sensor provided corresponding to the specific component or indirectly based on either the operating state of the fuel cell system or the external air temperature.
US08420271B2 Method to improve reliability of a fuel cell system using low performance cell detection at low power operation
A system and method for detecting a low performing cell in a fuel cell stack using measured cell voltages. The method includes determining that the fuel cell stack is running, the stack coolant temperature is above a certain temperature and the stack current density is within a relatively low power range. The method further includes calculating the average cell voltage, and determining whether the difference between the average cell voltage and the minimum cell voltage is greater than a predetermined threshold. If the difference between the average cell voltage and the minimum cell voltage is greater than the predetermined threshold and the minimum cell voltage is less than another predetermined threshold, then the method increments a low performing cell timer. A ratio of the low performing cell timer and a system run timer is calculated to identify a low performing cell.
US08420267B2 Methods and systems for producing hydrogen and system for producing power
Provided herein are methods and systems of producing hydrogen using ammonia borane, which has a high hydrogen density while being stable and easily stored. Ammonia borane may be exothermically reacted with a strong oxidizer, such as a mixture of hydrogen peroxide and water. The reaction between ammonia borane and the strong oxidizer may occur spontaneously and may produce heat. Unreacted ammonia borane may be exposed to and thermally decomposed using the heat produced during the exothermic reaction between ammonia borane and the strong oxidizer. The heat may be retained by performing the reactions in a vessel or reactor including a material capable of retaining the heat. A high gravimetric hydrogen yield is obtained from the reaction of ammonia borane with hydrogen peroxide and the thermal decomposition of unreacted ammonia borane. Hydrogen production using the methods and systems may yield a high gravimetric hydrogen content of at least about 10%.
US08420264B2 Method for preparing a lithium ion cell
The apparatus and methods described herein generally relate to a method for preparing electrodes for lithium ion cells, where both the positive and negative electrodes of the cell include metal oxides processed according to the methods described herein.
US08420263B2 Electrode collector manufacturing method and manufacturing apparatus, and battery provided with said collector
An electrode collector manufacturing apparatus (50) includes a chamber (51), the inside of which can be reduced in pressure, a substrate retaining mechanism (55) that retains a conductive substrate (12), and a gas introducing mechanism (54) that introduces a fluorine gas and an inert gas into the chamber (51). Inside the chamber (51) are provided an etching portion (52) that etches a surface of the substrate (12), and carbon film forming portions (56a) and (56b) that form a carbon film on the surface of the etched substrate (12). The gas introducing mechanism (54) is structured to create in the chamber a mixed gas atmosphere in which the fluorine and the inert gas are mixed at a predetermined molar ratio.
US08420260B2 Binder for secondary battery exhibiting excellent adhesive force
The present invention relates to a binder for an electrode of a secondary battery, including polymer particles in which two or more types of monomers are polymerized with two or more types of cross-linking agents with mutually different molecular weights. The binder, through which the combination of the specific ingredients above, fundamentally improves electrode stability, starting from the manufacturing process of an electrode, to thereby provide a secondary battery with excellent cycle characteristics.
US08420255B2 Storage cell and method of manufacturing same
A storage cell includes a storage element including first and second electrodes which are opposite to each other in a predetermined direction, a first terminal bonded to the first electrode, a second terminal bonded to the second electrode, and an outer resin covering the storage element to expose an outer surface of the first terminal and an outer surface of the second terminal from the outer resin. The storage element has substantially a rectangular shape viewing from the predetermined direction. The outer resin has substantially a rectangular shape viewing from the predetermined direction. The outer resin has first and second surfaces opposite to each other, and has a third surface connected with the first surface and the second surface. The first terminal is exposed on the first surface of the outer resin. The second terminal has a shape extending beyond the storage element along the first and third surfaces, and is exposed on the first surface. This storage cell has a small size, a large capacitance, and high reliability.
US08420253B2 Secondary battery
A secondary battery, sheathes a protection circuit board with a separate cover, connects the sheathed protection circuit board to a bare cell, and executes a molding or hard pack operation with a molding resin member in a space between the protection circuit board and the bare cell. The secondary battery may be constructed with a rechargeable bare cell, a protection circuit board supporting a protection circuit electrically connected to the bare cell and an external terminal, a board exterior cover adhering to the protection circuit board and the board exterior cover exposing the external terminal, and a first lead plate and a second lead plate that electrically connect the bare cell to the protection circuit board.
US08420248B2 Electrode assembly and secondary battery using the same
An electrode assembly and a secondary battery including the same. The electrode assembly includes: a positive electrode plate including a positive electrode active material applied to a positive electrode collector; a negative electrode plate including a negative electrode active material applied to a negative electrode collector; a separator disposed between the positive electrode plate and the negative electrode plate; and a ceramic layer disposed on a portion of the positive or negative electrode plate, adjacent to an outer surface of the electrode assembly. The positive electrode plate, the negative electrode plate, ceramic layer, and the separator are wound together. The ceramic layer prevents a short-circuit between the positive electrode plate and the negative electrode plate, and extends along between about 40% and 90% of the length of the positive or negative electrode plate, from a winding end thereof.
US08420245B2 Middle or large-sized battery pack case providing improved distribution uniformity of coolant flux
Disclosed herein is a middle- or large-sized battery pack case in which a battery module having a plurality of stacked battery cells, which can be charged and discharged, is mounted, wherein the battery pack case is provided with a coolant inlet port and a coolant outlet port, which are disposed such that a coolant for cooling the battery cells can flow from one side to the other side of the battery module in the direction perpendicular to the stacking direction of the battery cells, and the battery pack case is further provided with beads formed in a concavo-convex shape for improving the structural stability of the battery pack case against an external force, the beads being constructed in an outwardly-protruding structure to allow the coolant to be uniformly introduced into the battery module from the coolant inlet port in the advancing direction of a fluid in a flow space (“inlet duct”) defined between the coolant inlet port and the battery module.
US08420243B2 Battery pack
Two batteries are made mountable like a cartridge in a housing to achieve the large capacity of a battery pack and to improve the facilitation of operation such as replacement of a battery.The battery pack includes covers 2, 3 having four circumferential lateral surfaces one of which is opened; a lid body 5 opening and closing the opened lateral surface 4 of the housings; and a plurality of batteries 6a, 6b attached into and removed from the inside of the housing. The housing are formed to be divided in two portions one of which is a top cover 2 having the open lateral surface, another one of the two portions being a rear cover 3 mounted with a control substrate mounted thereon. The inside of the top cover is vertically divided in two by a partition plate 8 to form battery-storing portions 9a and 9b which can store the battery cartridges 6a and 6b, respectively.
US08420240B2 Method for controlling sodium-sulfur batteries
When charge power or discharge power of each individual sodium-sulfur battery included in a plurality of sodium-sulfur batteries becomes 1/n (n is a natural number) or less of a rated output, individual sodium-sulfur batteries are sequentially stopped. This prevents the discharge power (or the charge power) of the sodium-sulfur battery from becoming minute, so that a battery depth (or a stored energy) of the sodium-sulfur battery can be accurately managed.
US08420238B2 Use of a tungsten bronze structured material and turbine component with a thermal barrier coating
A tungsten bronze structured ceramic material as a thermal barrier coating is described wherein the tungsten bronze structured ceramic coating material has the formula AO—BvOw—CyOz where O stands for Oxygen, A stands for a 2+ or a 1+ cation, B stands for a 2+ or 3+ cation and C stands for a 4+ or a 5+ cation. The thermal barrier coating may be applied for gas turbine components.
US08420237B1 Adherent coating on carbide and ceramic substrates
An adherent coating for carbide and ceramic substrates employs a thin layer of hafnium nitride (HfN) between the substrate and a subsequent layer or layers. The thin layer may be employed without thermal cracking due to heat during use, such as for the insert of a cutting tool, because the upper layer or layers provide a gradual transition of material properties to a harder, less thermally conductive material on the outermost layer. A particular arrangement of layers on the carbide or ceramic substrate and hafnium nitride layer may be, from innermost to outermost layer, titanium carbide, aluminum oxide, and titanium nitride.
US08420235B2 Emissive diaryl acetylenes
Disclosed herein are compounds represented by a formula: Compositions and light-emitting devices related thereto are also disclosed.
US08420234B2 Organic electroluminescent device
An organic electroluminescent device is provided and includes: a pair of electrodes; an organic layer including a light emitting layer between the electrodes. The organic layer contains a compound represented by formula (I). In formula (I), R11, R12, and R13 each independently represents a C1-6 alkyl group, Q1 represents a carbon atom or a silicon atom, R14 represents a hydrogen atom or -Q2(R16)(R17)R18 in which Q2 represents a carbon atom or a silicon atom and R16, R17, and R18 each independently represents a C1-6 alkyl group, R15 represents a hydrogen atom, a substituted or unsubstituted alkyl group, a cyano group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group, and n stands for 1 or 2.
US08420229B2 OLED device with certain fluoranthene light-emitting dopants
An OLED device comprising a cathode, an anode, and having therebetween a light emitting layer and an electron-injecting layer, where (a) the light emitting layer contains a host and up to 50 volume % of a light-emitting fluoranthene compound with a 7,10-diaryl substituted fluoranthene nucleus having no aromatic rings annulated to the fluoranthene nucleus; and (b) the electron-injecting layer being located between the cathode and the light-emitting layer contains an organic alkali metal compound. It provides reduced drive voltage, operational stability and luminance of OLED devices.
US08420228B2 Organic electroluminescence display with intermediate layer and method for fabricating the same
Disclosed herein is an organic electroluminescent (EL) device comprising an intermediate layer made of at least one selected from a hole blocking material and an electron blocking material.
US08420221B2 Semiaromatic moulding compositions and uses of these
A polyamide molding composition with the following constitution is described: (a) from 40 to 90% by weight of a copolyamide, where this is composed of (a1) 1,6-hexanediamine and 1,10-decanediamine and also (a2) terephthalic acid and at least one other polyamide-forming monomer selected from the group of: dicarboxylic acid having from 8 to 18 carbon atoms, laurolactam, aminolauric acid, and/or mixtures thereof; (b) from 10 to 40% by weight of macromolecular plasticizers, with the proviso that these can have been replaced to some extent by low-molecular-weight plasticizers; (c) from 0 to 20% by weight of additives and/or added substances. Uses of this type of molding composition are also described, in particular for the production of a fuel line, cooling line, oil line or urea line for the automobile sector, as also are production processes to give moldings.
US08420219B2 Method for the application of corrosion-resistant layers to metallic surfaces
Method of applying corrosion control coats, especially integrated pretreatment layers or coats for atmospheric corrosion control, to metallic surfaces, using copolymers comprising as monomeric building blocks 20% to 70% by weight of monomers containing nitrogen heterocycles, 10% to 50% by weight of monomers containing acidic groups, 10% to 50% by weight of vinylaromatic monomers, and optionally 0% to 25% by weight of further monomers. Copolymers of the stated composition, and also preparations for applying corrosion control coats.
US08420205B2 Mixed media artwork and methods of creation
A method of making mixed media artwork includes cutting a metal sheet; applying an adhesive layer to an outer surface of the metal sheet; applying one or more polymer layers to the adhesive layer, wherein the one or more polymer layers create an image on the outer surface; and deforming the metal sheet to create a three-dimensional outer surface.
US08420200B2 Preform for optical element and optical element
A preform for an optical element is provided which involves less amount of deformation of glass in molding, and readily improves lifetime of the mold. The present preform for molding an optical glass element 10 exhibits an almost circular shape having a predetermined diameter in top view, exhibits a flattened semicircular shape having a predetermined overall height in side view, has a concave face on the top surface such that the predetermined overall height is attained at approximately the central position of the aforementioned circular shape, and has a concave face so as to fit along the convex face of the top surface such that a space is provided on the bottom face. The under surface may be either a concave face or a convex face. Also, the top surface may be either a concave face or a convex face.
US08420199B2 Sheet for multilayer optical recording medium and multilayer optical recording medium using the same
Disclosed is a sheet for producing a multilayer optical recording medium having a repeating structure wherein a plurality of optical recording layers are laminated. The sheet for a multilayer optical recording medium has a structure having a unit wherein an optical recording layer and an adhesive layer are laminated, or a structure having a unit wherein an optical recording layer, a barrier layer and an adhesive layer are laminated in this order. The maximum height roughness (Rz) of the optical recording layer or the barrier layer is not more than 500 nm. A multilayer optical recording medium is produced by using the sheet for a multilayer optical recording medium. Also disclosed is a sheet for producing, with high precision, a high-quality multilayer optical recording medium having a repeating unit wherein a plurality of optical recording layers containing a multiphoton absorbing material are laminated. A multilayer optical recording medium is also produced by using this sheet.
US08420197B2 Injection molding process for molding mechanical interlocks between molded components
A two-shot or multi-shot multi-material injection molding process is provided. The process allows dissimilar materials to be injection molded to form a single, injection molded part by creating a structural interlock between the materials to prevent the materials from separating. The structural interlock is formed by forming at least one interlock cavity adjacent to a interfacial surface of a first portion of a molded part molded from a first material, and injecting a second, different material into the mold so that the second material flows into the interlock cavity and fills it. Solidification of the second material in the interlock cavity formed by the first material creates the structural interlock between the two materials.
US08420188B2 Resin member fitting structure and passenger compartment antenna device
A resin member fitting structure including a first resin member, which is a rectangular hollow tube, has at least one inner wall surface. A second resin member, which is a hollow or solid rectangular tube, has at least one outer wall surface fitted to the at least one inner wall surface of the first resin member. The inner wall surface of the first resin member and the outer wall surface of the second resin member come into contact with each other and define at least one set of fitting surfaces. The second resin member has a hygroscopic expansion coefficient that is smaller than that of the first resin member. The at least one fitting surface includes a plurality of recess-projection engagement structures spaced apart from each other in a circumferential direction that intersects a longitudinal direction of the first and second resin members.
US08420185B1 Method for forming metal film with twins
A method for forming a metal film with twins is disclosed. The method includes: (a) forming a metal film over a substrate, the metal film being made of a material having one of a face-centered cubic crystal structure and a hexagonal close-packed crystal structure; and (b) ion bombarding the metal film at a film temperature lower than −20° C. in a vacuum chamber and with an ion-bombarding energy sufficient to cause plastic deformation of the metal film to generate deformation twins in the metal film.
US08420183B2 Method of manufacturing composite material
Disclosed is a method of manufacturing a composite sheet. The method comprises (a) irradiating a sheet of fibers and a matrix film at an irradiation zone with a plasma at substantially atmospheric pressure, and (b) impregnating the sheet of fibers with the matrix at an adhesion zone. The processes (a) and (b) are performed simultaneously, and the matrix film is irradiated with a plasma at said irradiation zone after being unwound from a roller and prior to entering said adhesion zone.
US08420175B2 Composition containing crystalline cellulose composite
Disclosed is a composition containing 100 parts by mass of a pigment, 0.01-50 parts by mass of a cellulose composite and water. The composition has a solid content of more than 25% by mass, and a viscosity of not less than 30 mPa·S. The cellulose composite contains 0.5-50% by mass of a hydrophilic polymer having an acid value of not less than 2.0 and a weight average molecular weight of from 1×103 to 1×107 and 50-99.5% by mass of a crystalline cellulose. The cellulose composite has an average particle diameter of not more than 10 μm.
US08420174B2 Polymer composition for corrosion protection
The present invention relates to a composition for coating metallic surfaces, comprising a binder component; a corrosion inhibitor polymer based on an ethylenically monocarboxylic and dicarboxylic acid and, if appropriate, further ethylenical monomers, a solvent component, and, if appropriate, crosslinkable components, and also pigment/filler components. The invention further relates to processes for its preparation and also to methods of coating a metallic surface using the composition, to coated metallic surfaces thus obtained, and to the use of the composition as a primer, particularly in coil coating or in atmospheric corrosion control. After drying, the applied layer preferably has a thickness of at least 3.1 μm and is therefore thicker than a typical pretreatment layer.
US08420173B2 Production method of producing wrapper for cigarettes
A production method for producing a wrapper for cigarettes is provided wherein, with a web kept traveling, a combustion inhibitor in liquid form is intermittently applied to one surface of the web to form undried banded layers arranged with a predetermined space therebetween in the traveling direction of the web, water is applied to the surface of the web over its entire area before or after the combustion inhibitor is applied, and then the web is rapidly dried.
US08420170B2 Methods of forming glass on a substrate
Disclosed is a deposition process for forming a glass film. An embodiment comprising the steps of disposing a substrate in a chemical vapor deposition chamber and exposing the substrate surface to a SiO2 precursor gas, a carrier gas, and optionally a dopant gas in the presence of ozone and exposing the reaction volume of the gases above the substrate surface to a high intensity light source.
US08420165B2 Method for production of silver fine powder covered with organic substance, and silver fine powder
Provided is a method for producing a silver fine powder covered with an organic substance, which comprises a step of mixing (i) a dispersion of silver particles covered with a protective material X1 that comprises an organic compound having an unsaturated bond and having a molecular weight of from 150 to 1000 in a liquid organic medium A, (ii) a protective material X2 that comprises an organic compound of which the number of the carbon atoms constituting the carbon skeleton is smaller than that of the organic compound to constitute the protective material X1, and (iii) a liquid organic medium B of which the ability to dissolve the protective material X1 therein is higher than that of the liquid organic medium A, thereby promoting the dissolution of the protective material X1 in the liquid organic medium B and the adhesion of the protective material X2 to the surface of the silver particles. Accordingly, the invention provides an industrial, large-scale mass-production system for a silver fine powder covered with a protective material having a low molecular weight, of which the sintering temperature can be greatly lowered.
US08420158B2 Process for making electrodes for lithium based electrochemical cells
A process for making an electrode sheet for lithium electrochemical cells is disclosed. The process comprises the steps of: a) admixing a polyether polymer or copolymer soluble in water, at least one lithium salt, at least one electrochemically active material, water and an organic solvent miscible with water in a water/organic solvent ratio of a maximum of 50% organic solvent by volume to form a water-based solution/suspension containing by weight at least 20% active electrode material, at least 5% of a polyether polymer or copolymer, and at least 1.5% lithium salt; b) coating the water-based solution/suspension in the form of an electrode thin film onto an electrode support; and, c) drying the electrode thin film to obtain an electrode thin sheet having less than 1000 ppm of residual water.
US08420155B2 Alloyed semiconductor quantum dots and concentration-gradient alloyed quantum dots, series comprising the same and methods related thereto
An alloyed semiconductor quantum dot comprising an alloy of at least two semiconductors, wherein the quantum dot has a homogeneous composition and is characterized by a band gap energy that is non-linearly related to the molar ratio of the at least two semiconductors; a series of alloyed semiconductor quantum dots related thereto; a concentration-gradient quantum dot comprising an alloy of a first semiconductor and a second semiconductor, wherein the concentration of the first semiconductor gradually increases from the core of the quantum dot to the surface of the quantum dot and the concentration of the second semiconductor gradually decreases from the core of the quantum dot to the surface of the quantum dot; a series of concentration-gradient quantum dots related thereto; in vitro and in vivo methods of use; and methods of producing the alloyed semiconductor and concentration-gradient quantum dots and the series of quantum dots related thereto.
US08420151B2 Mixtures having a salty taste
The present invention relates to a mixture comprising or consisting of: (a) one or more inorganic salts which are suitable for nutrition and are not sodium chloride, (b) one or more mono- or polyvalent salts of polybasic food acids, (c) one or more amino acids, or salts thereof, which are suitable for nutrition.
US08420150B2 Compact plant powder product, method of making same, and use in preparing a hot drink
The present invention relates to tablets allowing hot drinks to be prepared by lixiviation and especially coffee. It also relates to the preparation method by which said tablets may be made.
US08420147B2 High-purity rebaudioside D and low-calorie cake containing the same
The invention provides methods of purifying Rebaudioside D from the Stevia rehaudiana Bertoni plant extract along with Rebaudioside A. The methods are useful for producing high purity Rebaudioside D and Rebaudioside A. The invention further provides a low-calorie cake containing the purified Rebaudioside D and a process for making the low-calorie cake containing the purified Rebaudioside D.
US08420146B2 High-purity Rebaudioside D and low-calorie bread containing the same
The invention provides methods of purifying Rebaudioside D from the Stevia rebaudiana Bertoni plant extract along with Rebaudioside A. The methods are useful for producing high purity Rebaudioside D and Rebaudioside A. The invention further provides a low-calorie bread containing the purified Rebaudioside D and a process for making the low-calorie bread containing the purified Rebaudioside D.
US08420144B2 Kokumi-imparting agent, method of using, and compositions containing same
The present invention encompasses a method for screening for a kokumi-imparting substance by using the calcium receptor activity as an index, a composition containing a kokumi-imparting substance obtained by the screening method, a method for producing food or drink imparted with kokumi, and food or drink imparted with kokumi.
US08420138B2 Method to produce chickens
A method for producing broiler chickens comprising feeding to the chickens a chicken feed comprising from 103 to 1011 CFU Bacillus bacteria per gram feed, characterized by that the chicken feed has a reduced metabolizable feed energy (ME) level of from 85% to 98% ME of the ME in a standard chicken feed (full ˜100% ME).
US08420135B2 Use of coconut water extract or coconut shell extract for treating immunological diseases and/or disorders
A method for treating immunological diseases and/or disorders associated with tumor necrosis factor-alpha (TNF-α) in a subject in need thereof is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of the coconut (Cocos nucifera Linn.) water extract or coconut (Cocos nucifera Linn.) shell extract through induction of transforming growth factor beta (TGF-β) or interleukin-10 (IL-10) as endogenous immunosuppressive factors.
US08420129B2 Chlorine dioxide solution composition
There are provided a chlorine dioxide solution composition whose solute includes dissolved chlorine dioxide and chlorite; and a solution composition encapsulating body including a glass vessel or enameled vessel and the chlorine dioxide solution composition hermetically sealed therein.
US08420128B2 Method of imparting heat resistance to lactoferrin
An agent for thermally stabilizing lactoferrin, which comprises a nucleic acid as an active ingredient, can be added to lactoferrin to impart thermal stability to lactoferrin. Thermally stabilized lactoferrin can be heat-sterilized at a pH value around a neutral pH value while keeping its activity.
US08420126B2 Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
US08420119B2 Drug composition for treating tumor with polymeric micelle encapsulating anti-neoplastic
This present disclosure relates to pharmaceutical compositions for treating tumors using a polymeric micelle encapsulating an anti-tumor drug. The polymeric micelle comprises block copolymers comprising at least one hydrophilic block, at least one hydrophobic block, and at least one zwitterion. The present disclosure also relates to methods of enhancing the solubility of such drugs, methods of increasing the blood circulating time of such drugs, and methods of delivering such drugs to one or more solid tumors.
US08420118B2 Anionic lipids and lipid nano-structures and methods of producing and using same
Anionic non-phospholipids, as well as lipid nanostructures formed therefrom, are disclosed herein. Also disclosed are methods of producing and using same.
US08420115B2 Oral preparations and process for production thereof
Disclosed herein are oral preparations and their production process. The oral preparations are each composed of a complex and a coating composition applied on the complex. The complex has been obtained by dispersing or dissolving a drug having an unpleasant taste and a gastric high-molecular compound in a low melting-point substance heated to and molten at its melting point or higher and granulating the resulting mixture. The coating composition is composed of an insoluble high-molecular compound and a disintegrator at a weight ratio of from 80:20 to 99:1. In the form of microparticles or the like that contain the drug having the unpleasant taste, each oral preparation according to the present invention can maintain the masking of the unpleasant taste of the drug and the release profile of the drug even under acidic conditions.
US08420114B2 Alpha and beta adrenergic receptor agonists for treatment of pain and / or inflammation
Effective treatments of pain and/or inflammation are provided. Through the administration of an effective amount of at least one alpha adrenergic agonist and at least one beta adrenergic agonist at or near a target site, one can reduce, prevent or treat pain and/or inflammation.
US08420110B2 Drug coated expandable devices
Medical devices may be utilized for local and regional therapeutic agent delivery. These therapeutic agents or compounds may reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including restenosis, vulnerable plaque, and atherosclerosis in type 2 diabetic patients.
US08420108B2 Flexible bone composite
The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least one calcium-containing layer. The polymeric layer can be a polymeric layer including a synthetic polymer. The calcium-containing layer can include a calcium compound such as β-Ca3(PO4)2. The flexible bone composites of the invention are useful as bone void fillers and have improved handling characteristics.
US08420106B1 Extramuscular treatment of traumatic-induced migraine headache
A method for selection and treatment of externally caused migraine headache, the method includes identifying a patient group having chronic migraine headache; determining the identified patient group, a specific patient with a post traumatic migraine headache; and administering to the selected patient by injection of a therapeutically effective amount of a Botulinum neurotoxin in a pharmaceutically safe form to the selected patient's head or upper neck; administration preferably being on the sites of the trigeminal cervical system, enabling axonal transport of the neurotoxin from distal to central sites; and the administration preferably comprising extramuscular injection of the neurotoxin of suitable dilution (a) over the aponeurotic fascia, or (b) intra-orally, in a foramina of the sphenopalatine ganglion, or (c) to emerging exit points of nerves including foraminal sites.
US08420103B2 Papillomavirus vaccines
A nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a therapeutic composition thereof is formulated into a drug product useful for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus; particular such vectors are nucleic acid molecules containing a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3′ portion of the first nucleotide which in the natural content is 100% identical to the 5′ portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%.
US08420091B2 Matriptase protein and uses thereof
The present invention provides methods and compositions for treatment, screening, diagnosis, prognosis and therapy of breast cancer, colorectal cancer, esophageal cancer, gastric cancer, prostate cancer and uterine cancer, for monitoring the effectiveness of breast cancer, colorectal cancer, esophageal cancer, gastric cancer, prostate cancer and uterine cancer treatment, and for drug development.
US08420090B2 Recombinant B. pseudomallei adhesin protein and methods and uses thereof
Isolated and/or recombinant adhesin polypeptides from Burkholderia pseudomallei are provided, which are used as vaccines. Genetic constructs comprising nucleic acid sequences encoding such polypeptides are also provided. Vectors comprising such constructs have been prepared and used for transforming host cells for producing the polypeptides of the invention. Antibodies to such polypeptides are also provided. Such antibodies can be used to detect the presence of B. pseudomallei or B. mallei and in methods of treating or preventing Burkholderia infection.
US08420089B2 Antagonists of IL-6 to raise albumin and/or lower CRP
The present invention is directed to therapeutic methods using IL-6 antagonists such as antibodies and fragments thereof having binding specificity for IL-6 to improve survivability or quality of life of a patient in need thereof. In preferred embodiments, the anti-IL-6 antibodies will be humanized and/or will be aglycosylated. Also, in preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level or a reduced serum albumin level prior to treatment. In another preferred embodiment, the patient's Glasgow Prognostic Score will be increased and survivability will preferably be improved.
US08420087B2 Interleukin-12 targeted to oncofoetal fibronectin
The invention provides a compound comprising a target specific portion and an effector portion wherein the target specific portion comprises or consists of a monoclonal antibody having specificity for oncofoetal fibronectin, or a fragment or variant thereof which retains the antigen binding specificity of the parent monoclonal antibody and the effector portion comprises or consists of interleukin-12, or a functional fragment or variant thereof, characterized in the monoclonal antibody having specificity for oncofoetal fibronectin binds to a region of oncofoetal fibronectin other than the ED-B region. The invention further provides nucleic acids encoding the compounds of the invention, and the use of such compounds in medicine, e.g. in the treatment of cancer.
US08420084B2 Fully human antibodies specific to CADM1
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, more particularly engineered antibodies resulting in increased binding to Fc receptors and/or increased potency for ADCC or immunoconjugates, which specifically bind to CADM1 with high affinity. Nucleic acid molecules encoding CADM1 antibodies, expression vectors, host cells and methods for expressing the CADM1 antibodies are also provided. Bispecific molecules and pharmaceutical compositions comprising the CADM1 antibodies are also provided. Methods for detecting CADM1, as well as methods for treating various cancers, including lung cancer and pancreatic cancer, are disclosed.
US08420083B2 Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
The present application relates to antibodies, such as monoclonal antibodies, and in particular CDR grafted, humanized versions thereof, for the treatment and diagnosis of pain and other neuroinflammatory conditions associated with the Receptor for Advanced Glycation End Products (RAGE).
US08420080B2 Methods for treating adult respiratory distress syndrome
We have discovered that the activated phosphorylated form of focal adhesion kinase (hereafter “FAKp”) strengthens the microvascular endothelial cell (EC) junctions that form a barrier in pulmonary endothelia, and the increased barrier helps to prevent acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Thus certain embodiments of the invention are directed to prevention and treatment of ALI and ARDS by administering a therapeutically effective amount of FAKp to subjects at risk of developing or diagnosed as having either ALI or ARDS.
US08420079B2 Recombinantly modified plasmin
Polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided. The plasmin(ogen) molecule has a single kringle domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme.
US08420076B2 Therapy or prophylaxis of Klebsiella pneumoniae infections with a lytic bacteriophage specifically against the K. pneumoniae
A therapy or prophylaxis of K. pneumoniae infections with a lytic bacteriophage specifically against K. pneumoniae, provides a lytic bacteriophage (DSM 24329) to a K. pneumoniae infected organism for the sake of relieving the serious complications of liver abscesses and bacteremia, and the high mortality rate of K. pneumoniae infections in Taiwan.
US08420070B2 Controlling sugar feeding insects
Methods for controlling sugar feeding insects by a chemical compositions which includes mixing an extract of flowers and of fruit, or their components in water with predetermined amount of sugar mixture and oral toxin. The methods also concern applying an effective amount of the insect bait to an area to be controlled and trapping or killing the insects by a bait stations. Methods of applying and the parameters of choosing a suitable location for applying the bait are disclosed.
US08420069B2 Antimicrobial and antifouling polymeric materials
A polymeric material, methods of making the polymeric material, articles that include the polymeric material, and compositions that contain the polymeric material are provided. The polymeric material has a plurality of different pendant groups that include a first pendant group containing a —COOH group or a salt thereof, a second pendant group containing a poly(alkylene oxide) group, a third pendant group containing a silicon-containing group, and a fourth pendant group containing a quaternary amino group. The polymeric material can be used, for example, to provide coatings that can be antifouling, antimicrobial, or both.
US08420068B2 Polymer-based compositions and conjugates of antimicrobial agents
Provided herein are water-soluble polymer conjugates and polymer-based compositions of antimicrobial agents. Also provided are methods for synthesizing and administering such conjugates and compositions.
US08420062B2 Non-aerosol/aerosol dispensing of sunscreen sprays comprising spherical porous silica microparticles
Nonaerosol/atomizer pumps or aerosol dispensers comprise (A) a reservoir confining at least one vaporizable sunscreen composition suited for UV-photoprotecting the skin and/or hair against the damaging effects of UV radiation, the at least one vaporizable sunscreen composition comprising (1) a UV-photoprotecting amount of at least one UV-sunscreen and (2) an SPF-enhancing amount of generally spherical silica microparticles, formulated into (3) a topically applicable, cosmetically acceptable carrier therefor, and (B) at least one agent for pressurizing the at least one vaporizable sunscreen composition into a spray of fine sunscreen particles.
US08420061B2 Ultraviolet absorber water-dispersed composition
Disclosed is an ultraviolet absorber water-dispersed composition, comprising the following components (A) and (B); (A) a benzotriazole-type ultraviolet absorber represented by general formula (1) below wherein R1 and R2 denote alkyl groups having a carbon number from 1 to 18, may be identical or different, and may be substituted by one or two or more groups selected from the group consisting of alkyl groups having a carbon number from 1 to 4, and cycloalkyl groups and aryl groups both having a carbon number from 5 to 12; and (B) polyglycerol monoalkyl ester with a mean degree of polymerization of glycerol of 5 or more. The water-dispersed composition is capable of stably maintaining the dispersed state of benzotriazole-type ultraviolet absorbers even in the presence of salt.
US08420060B2 Pharmaceutical aerosol formulations of formoterol and beclometasone dipropionate
Pharmaceutical formulations comprising beclometasone dipropionate and a salt of formoterol exhibit improved stability and are useful in pressurized metered dose inhalers (pMDIs).
US08420057B2 Capsule having broad color spectrum
The present invention is directed to a capsule comprising a water-soluble compound suitable for the capsule, a non-water soluble excipient suitable for the capsule; and suitable for the capsule, and a mixture of colorant agents, wherein the color of the capsule may be in the range of 15
US08420052B2 Imaging agents useful for identifying AD pathology
Provided herein are compounds and compositions which comprise the formulae as disclosed herein, wherein the compound is an amyloid binding compound. An amyloid binding compound according to the invention may be administered to a patient in amounts suitable for in vivo imaging of amyloid deposits, and distinguish between neurological tissue with amyloid deposits and normal neurological tissue. Amyloid probes of the invention may be used to detect and quantitate amyloid deposits in diseases including, for example, Down's syndrome, familial Alzheimer's Disease. In another embodiment, the compounds may be used in the treatment or prophylaxis of neurodegenerative disorders. Also provided herein are methods of allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing a neurodegenerative disease.
US08420049B2 Labeled adenosine for use in positron emission tomography
Radiolabeled adenosine or radiolabeled adenosine containing molecules for use in positron emission tomography for assessing alterations in adenylate metabolism in a patient are provided.
US08420047B2 Hydrogenation of aluminum using a supercritical fluid medium
An apparatus and a method for controllably converting aluminum into alane. In the system of the invention, a reaction between aluminum and hydrogen to form alane is performed at temperatures below 100° C. using a supercritical fluid such as CO2 as a reaction medium, with the optional inclusion of a co-solvent, such as an ether, in the reaction vessel. Inert gas is used to exclude unwanted gases such as oxygen. The reaction of aluminum and hydrogen has been observed to proceed at approximately 60° C. using Me2O as an added solvent in CO2 at supercritical pressures.
US08420046B1 Method of preparing high crystalline nanoporous titanium dioxide photocatalyst
Disclosed is a method of preparing high crystalline nanoporous titanium dioxide photocatalyst, capable of preparing the high crystalline nanoporous titanium dioxide photocatalyst in mass production through a simply synthesis method using an ultrasonification. The method includes the steps of (a) mixing a titanium precursor and a surfactant in a first solvent and performing a sol-gel reaction; (b) maturing a reactant obtained through the sol-gel reaction for 15 hours to 25 hours; (c) filtering the matured reactant and washing the matured reactant; (d) primarily drying the washed reactant at a temperature of 20° C. to 50° C. to obtain titanium sediments; (e) mixing the titanium sediments in a second solvent and performing an ultrasonification with respect to the mixed solution for 10 minutes to 120 minutes; and (f) secondarily drying the mixed solution, which has been subject to the ultrasonification, at a temperature of 15° C. to 45° C. to obtain titanium dioxide photocatalytic particles.
US08420043B2 Nano-crystal diamond film, manufacturing method thereof, and device using nano-crystal diamond film
A nano-crystal diamond film synthesized on a substrate and containing, as a major component, nano-crystal diamond having a grain diameter from 1 nm to less than 1000 nm. This nano-crystal diamond film can be formed on a substrate by means of a plasma CVD method using a raw material gas containing a hydrocarbon and hydrogen, allowing the formation of the nano-crystal diamond film to take place outside the plasma region. This nano-crystal diamond film is applicable to the manufacture of an electrochemical device, an electrochemical electrode, a DNA chip, an organic electroluminescent device, an organic photoelectric receiving device, an organic thin film transistor, a cold electron-emission device, a fuel cell and a catalyst.
US08420040B2 Organic-inorganic composite and polymeric composite material, and method producing them
An organic-inorganic composite is useful as a sheeted filler having a high aspect ratio. A positively charged organic compound is intercalated into a non-swelling layered silicate that is composed of mica and has K ions between the layers, and has primary particles of 2 μm to 500 μm as an average particle size. The layered silicate is represented as the formula: (KaM0.1-b)(XcYd)(Si4-eAle)O10(OHfF2-f), wherein 0.6≦a≦1.0, 0≦b≦0.1, 1.0≦c≦3, 0≦d≦2, 2≦c+d≦3, 0≦e≦4, 0≦f≦2; M is a cation other than K which is between layers and at least one of Li, Na, Rb, Cs, NH4, Be, Mg, Ca, Sr, Ba, Mn, Fe, Ni, Cu, Zn and Al; X and Y are metals enclosed in an octahedral formed in a 2:1 typed sheet; X is at least one of Mg, Fe, Mn, Ni, Zn and Li; and Y is at least one of Al, Fe, Mn and Cr.
US08420037B2 Air pollution control system and air pollution control method
An air pollution control system includes a desulfurization apparatus 13 that reduces sulfur oxide contained in flue gas 12 supplied from a boiler 11; and a CO2 recovery apparatus 15 including a CO2 absorber 21 that reduces CO2 contained in flue gas 12 that has been desulfurized by the desulfurization apparatus, with the aid of an amine absorbent and an absorbent regenerator 22 that regenerates the amine absorbent. Part 14a of desulfurized flue gas 14 containing SOx is supplied to treated flue gas 16, from which CO2 has been reduced and which is discharged from a top portion of the CO2 absorber 21, so that remaining mist amine accompanying the treated flue gas 16 is neutralized to amine sulfate or amine sulfite.
US08420028B2 Cell isolation apparatus
A cell isolation apparatus includes: a cylinder member that is inserted into a container into which a reagent is to be introduced; a net which is stretched over the cylinder member; a tissue acquiring unit that is projected from the cylinder member; and a bottom lid portion that is configured by a bottomed pipe in which a first hole that communicates an interior with an exterior is formed, and that is fitted to a bottom portion of the cylinder member in a state where the net and the tissue acquiring unit are accommodated.
US08420027B2 Dosing device for liquids
The invention relates to a dosing device for liquids, with a replaceable distributor rail (1) and a plurality of dosing units (2) that are hydraulically connected to the distributor rail (1), wherein each dosing unit (2) has a valve unit (3), preferably provided with a suction valve, a discharge valve and a discharge cannula (7), and, detachably arranged on the valve unit (3), a piston-cylinder unit (8) for drawing in and measured discharging of the liquid, wherein each valve unit (3) has a hydraulic connection element for detachable hydraulic connection to the distributor rail (1), wherein the distributor rail (1) has an elongate fluid supply line, which has at its end side a supply connection (14) for the liquid and has dosing unit connections which are detachably coupled to the hydraulic connection elements of the dosing units (2).
US08420026B2 Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device
A centrifugal force-based microfluidic device for nucleic acid extraction and a microfluidic system are provided. The microfluidic device includes a body of revolution; a microfluidic structure disposed in the body of revolution, the microfluidic structure including a plurality of chambers, channels connecting the chambers, and valves disposed in the channels to control fluid flow, the microfluidic structure transmitting the fluid using centrifugal force due to rotation of the body of revolution; and magnetic beads contained in one of the chambers which collect a target material from a biomaterial sample flowing into the chamber, wherein the microfluidic structure washes the magnetic beads which collect the target material, and separates nucleic acid by electromagnetic wave irradiation from an external energy source to the magnetic beads. The microfluidic system includes the microfluidic device; a rotation operating unit which rotates the body of revolution; and an external energy source which irradiates electromagnetic waves.
US08420023B2 Microfibrous media and packing method for optimizing and controlling highly exothermic and highly endothermic reactions/processes
A vessel packed with a microfibrous media made of micron-sized highly conductive fibers, which are able (and may be used) to immobilize various reactive materials including catalysts, sorbents, electrocatalysts, and other chemically reactive solids. The vessel enables fine temperature control and a uniform temperature profile for a range of highly endothermic or exothermic chemical reactions, sorptions, separation processes, mixing operations, and heat transfer applications.
US08420018B2 Gas hydrate production apparatus
A gas hydrate production apparatus capable of reacting a raw gas with a raw water to thereby form a slurry gas hydrate and capable of removing water from the slurry gas hydrate by means of a gravitational dewatering unit. The gravitational dewatering unit is one including a cylindrical first tower body; a cylindrical dewatering part disposed on top of the first tower body; a water receiving part disposed outside the dewatering part; and a cylindrical second tower body disposed on top of the dewatering part, wherein the cross-sectional area of the second tower body is continuously or intermittently increased upward from the bottom.
US08420017B2 Microfluidic reaction apparatus for high throughput screening
A microfluidic device is described that has a slug mixing arrangement. A reaction well has an input flow channel with a first valve near the reaction well, and a second valve further from the reaction well. A fluid source is connected to the segment in between the two valves. A second fluid source is connected behind the second valve. The channel between the two valves receives the first fluid by blind filling when the two valves are closed. The reaction well receives the first fluid followed by the second fluid when the first and second valves are open.
US08420015B2 Systems and methods for thermal actuation of microfluidic devices
A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component has at least two terminals. Each terminal is in electrical communication with at least one contact. The number of contacts required to independently control the N components is substantially less than the total number of terminals. Upon actuation, the components typically heat a portion of the microfluidic network and/or sense a temperature thereof.
US08420008B2 Side well for metal melting furnace
An exemplary embodiment of the invention provides a side well for a metal melting furnace. The side well comprises an insulated body having a front wall adapted to form part of an insulated side wall of a metal melting furnace and a top, a cavity within the body including a single upright well having a cylindrical wall adjacent to a closed bottom of the cavity, an entrance to the cavity at the top of the insulated body, a metal inlet channel leading directly into the cavity from an inlet aperture in the front wall, and a metal outlet channel leading directly from the cavity to a metal outlet aperture in the front wall. The side well includes a rotatable impeller having a vertical rotatable shaft and at least one vaned section positioned at a lower end of the rotatable shaft; wherein the impeller extends into the cavity with the vaned section positioned in the well adjacent to the cylindrical wall.
US08420004B2 Meltblown wetlaid method for producing non-woven fabrics from natural cellulose
The present invention provides a meltblown wetlaid method for producing non-woven fabrics from natural cellulose using pulp as raw material and N-methylmorpholine N-oxide (NMMO) as solvent for dissolving into dope. The dope is then extruded out of a spinneret to form filament bundle by meltblown method. Subsequently, by means of ejecting mist aerosol of water, the filament bundle is coagulated with regeneration. Via post treatments of water rinsing, hydro-entangled needle punching, drying, winding-up and the like have been orderly applied, then final product of nonwoven fabrics with continuous filament are produced from natural cellulose.
US08420001B2 Influencing specific mechanical properties of three-dimensional objects manufactured by a selective sintering by means of electromagnetic radiation from a powder comprising at least one polymer or copolymer
A three-dimensional object is manufactured from a powder of polymer material by selective sintering process by means of electromagnetic radiation of the powder, wherein the powder comprises a preselected polymer or copolymer and is subjected to selective sintering such that the manufactured three-dimensional object has a final crystallinity which is in such a range that the balance of properties, in particular mechanical properties including Young's modulus, tensile strength and elongation at break, is improved.
US08420000B2 Highly crystalline polyethylene
The present invention relates to methods for making highly crystalline polymeric material, for example, highly crystalline cross-linked and not cross-linked ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making additive-doped highly crystalline polymeric material using high pressure and high temperature crystallization processes, medical implants made thereof, and materials used therein.
US08419999B2 Method for producing ethylene-vinyl alcohol copolymer resin, ethylene-vinyl alcohol copolymer resin, and multilayer structure
Provided is by the present invention is a method for producing an EVOH resin having sufficient long-run workability in melt molding and enabling prevention of coloring such as yellowing, an EVOH resin obtained by this method for production, and a laminate obtained from this resin.The present invention is a method for producing an ethylene-vinyl alcohol copolymer resin, the method including a step of saponifying an ethylene-vinyl ester copolymer to obtain an ethylene-vinyl alcohol copolymer, in which the method is characterized by further including a step of irradiating the ethylene-vinyl ester copolymer or the ethylene-vinyl alcohol copolymer with an infrared ray.
US08419996B2 Print head assembly for use in fused deposition modeling system
A print head assembly that includes a print head carriage and multiple, replaceable print heads that are configured to be removably retained in receptacles of the print head carriage.
US08419995B2 Imprint method
An imprint method includes applying a light curable resin on a substrate to be processed, the substrate including first and second regions on which the light curable resin is applied, contacting an imprint mold with the light curable resin, curing the light curable resin by irradiating the light curable resin with light passing through the imprint mold, generating gas by performing a predetermined process to the light curable resin applied on a region of the substrate, the region including at least the first region, wherein an amount of gas generated from the light curable resin applied on the first region is larger than an amount of gas generated from the light curable resin of the second region, and forming a pattern by separating the imprint mold from the light curable resin after the gas being generated.
US08419994B2 Manufacturing method of foldable artificial vitreous body and mould thereof
The present invention relates to a foldable capsular vitreous body (FCVB), and its mold design, method for manufacturing, product appearance, and drug delivery property and so on. A mold for molding a foldable artificial vitreous body comprises an upper mold (1), a lower mold (2) and a core (3). The core (3) is disposed between the upper mold (1) and the lower mold (2) and is connected with a drainage-tube pin connected with an injection channel (4). Heating holes (6) are disposed in the upper mold (1) and/or the lower mold (2). Material is injected to the mold and is heated to vulcanize to mold vitreous body. The FCVB is adapted to be injected with any harmless medium and can be used as a delivery vehicle inside or around the eye ball. The size or shape of the FCVB can be changed depending on the different implant site.
US08419987B2 Extruder system for extruding a fluid
The invention relates to an extruder system for extruding a fluid with at least one supply device, at least one mixer device and at least one extrusion die. In accordance with the invention at least one device for producing a fluid flow (transport fluid) that completely or partially surrounds the material to be extruded that essentially runs parallel to the outlet direction of the material to be extruded is provided, and whereby the fluid is discharged from the extruder system by suction and/or pressure of the transport fluid flow by means of an expulsion gas. The extruder system allows even product discharge for products well into the nanometer range.
US08419985B2 Polymeric nanoparticles comprising a medium for photon up-conversion
The present invention relates to a polymeric nanoparticle comprising a medium for photon up-conversion, and to a method of producing such polymeric nanoparticle.
US08419984B2 Super-pyroelectric films and process of their preparation
A film is presented having super-pyroelectric properties. The film comprises nano-sized grains being in a ferroelectric phase and having at least three different crystallographic variants defining at least two polycrystalline macro-domains. The film is shaped to define at least one film region with the macro-domains of a predetermined shape and different orientations of crystallographic axes with respect to the film's surface, thereby enabling to apply a temperature change to the film to induce movement of the polycrystalline macro-domains boundaries enabling super-pyroelectric properties.
US08419982B2 Conductive compositions and method
Conductive compositions for use with medical electrodes are provided. The conductive compositions utilize a surfactant capable of both reducing the surface tension of the conductive composition as well as increasing the viscosity of the conductive composition. Methods of preparing these conductive compositions are also provided.
US08419981B2 Conductive paste composition and electrode prepared using the same
A conductive paste composition and an electrode prepared using the same, the conductive paste composition including a conductive powder a binder resin; and a solvent, wherein the conductive powder includes a flake type powder having an average particle diameter (D50) of about 1.2 μm to about 3.0 μm, and a spherical powder having an average particle diameter (D50) of about 0.2 μm to about 2.0 μm, the flake type powder and the spherical powder are present in a weight ratio of about 1:0.4 to about 1:2, and the conductive powder and the binder resin are present in a weight ratio of about 1:0.04 to about 1:0.08.
US08419975B2 Phosphor composition and method for producing the same, and light-emitting device using the same
A light-emitting device is produced using a phosphor composition containing a phosphor host having as a main component a composition represented by a composition formula: aM3N2.bAlN.cSi3N4, where “M” is at least one element selected from the group consisting of Mg, Ca, Sr, Ba, and Zn, and “a”, “b”, and “c” are numerical values satisfying 0.2≦a/(a+b)≦0.95, 0.05≦b/(b+c)≦0.8, and 0.4≦c/(c+a)≦0.95. This enables a light-emitting device emitting white light and satisfying both a high color rendering property and a high luminous flux to be provided.
US08419972B2 Polymerizable liquid crystal composition
A polymerizable liquid crystal composition is provided that is excellent in UV curing characteristics in the air and is excellent in orientation homogeneity, and a polymer film as a selective reflection film is provided that is obtained by orienting and polymerizing the composition on a supporting substrate. The liquid crystal composition contains a compound (1), a compound (2), a compound (3), a compound selected from a group of compounds represented by the formulae (4) to (6), and a surfactant. In the following formulae Y1 to Y4 and Y6 are each alkylene, A2, A3, A41, A42, A51, A52 and A6 are each a cyclic group, Z2 to Z4 and Z6 are each a bonding group, P4 and P6 are each an integer of from 0 to 3, R2, R31 and R32 are each hydrogen, halogen or alkyl, and Q1 and Q2 are each a polymerizable group.
US08419965B1 System and method for texturing glass
A method for texturing a glass substrate includes cleaning the glass substrate with at least one surfactant and etching the glass substrate using a caustic solution. The percentage of caustic solution is provided by controlling a fluid flow and temperature to control the depth of the etching. The method also includes acid cleaning the etched glass substrate to remove glass residuals and surfactants.
US08419964B2 Apparatus and method for edge bevel removal of copper from silicon wafers
Chemical etching methods and associated modules for performing the removal of metal from the edge bevel region of a semiconductor wafer are described. The methods and systems provide the thin layer of pre-rinsing liquid before applying etchant at the edge bevel region of the wafer. The etchant is less diluted and diffuses faster through a thinned layer of rinsing liquid. An edge bevel removal embodiment involving that is particularly effective at reducing process time, narrowing the metal taper and allowing for subsequent chemical mechanical polishing, is disclosed.
US08419963B2 Polishing method
A defect distribution in the vicinity of a surface of a glass substrate is inspected by a positron annihilation gamma ray measurement. A buffer layer including a brittle layer and/or a coating layer is created on the surface of the glass substrate. The brittle layer is formed by irradiating a gas cluster ion on the surface to deteriorate the glass. The coating layer is formed by coating the surface with a soft substance. Next, a thickness of the created buffer layer is measured by a positron annihilation gamma ray measurement. The surface of the glass substrate is then cleaned. To create a slurry, abrasive particles for the slurry are uniformly scattered on a polishing implement for polishing the glass substrate and a liquid component for the slurry is added thereto. The glass substrate is then chemically mechanically polished from the buffer layer with the slurry.
US08419960B2 Plasma processing apparatus and method
A plasma processing apparatus performs a process on a substrate by using plasma. The plasma processing apparatus includes a processing chamber; a mounting table which is located in the processing chamber and on which a substrate is mounted; a gas shower head formed of a conductive material provided to face the mounting table and having at the bottom surface thereof a plurality of gas injection openings for supplying a processing gas into the processing chamber; an induction coil to which a high frequency current is supplied to generate an inductively coupled plasma in a region surrounding a space below the gas shower head; a negative voltage supplying unit for applying a negative DC voltage to the gas shower head to allow an electrical field, which is induced by the induction coil, to be drawn to a central portion of the processing region; and a unit for evacuating the processing chamber.
US08419956B2 Surface emitting photonic device
A surface emitting photonic device including a substrate; and a waveguide structure on the substrate. The waveguide structure includes an active region along its longitudinal axis and the active region is for generating light. The waveguide structure also has a trench formed therein transverse to the active region and defining a first wall forming an angled facet at one end of the active region, the first wall having a normal that is at a non-parallel angle relative to the longitudinal axis of the waveguide structure. The trench also defines a second wall located opposite the first wall.
US08419953B1 Method and system for removing an antiferromagnetic seed structure
A method for fabricating a transducer on a substrate is described. The transducer includes an antiferromagnetic seed structure. The antiferromagnetic seed structure includes a first NiFe layer, a first multilayer including a first Ru layer, a second NiFe layer, and a second multilayer including a second Ru layer. The second multilayer, the second NiFe layer and part of the first Ru layer are removed using a first wet etch, which uses a first etchant combination to remove NiFe and in which Ru is insoluble. The second Ru layer is removed through lift-off due to etching of the second NiFe layer. A remainder of the first Ru layer is removed through a second wet etch, which uses a second etchant combination to remove Ru. A remaining portion of the first multilayer and the first NiFe layer are removed through a third etch, which uses a third etchant combination that removes NiFe.
US08419945B2 MECS dialyzer method
The present invention provides methods and apparatus for cleansing blood through hemodialysis by the process of diffusion across a membrane into dialysate. This dialyzer also removes solutes from the blood by a process of convection, where fluid and dissolved solutes pass through the membrane out of the blood. In one embodiment in accordance with the present invention, the MECS dialyzer uses a counter-flow between the dialysate and blood through a plurality of microchannels. The dialyzer comprises a plurality of flat semi-permeable membranes interleaved between microchannel sheets to define a plurality of flow channels. The stack of membranes and microchannel sheets are aligned and consolidated to form the MECS dialyzer. The MECS dialyzer acts as a flow manifold with ports and headers to collect the blood and dialysate and direct them to and from the microchannels.
US08419937B2 Filter device and filter element
A filter device has a cup-shaped filter housing (1), a filter element (13) in the housing and at least one end cap (21). A retaining device detachably fixes the filter element (13) along its longitudinal axis and has screwing elements (33, 41) interacting with each other and configured on the interior of the filter housing (1) and on the filter element (13). A sealing device (38) forms the seal between the filter element (13) and a housing terminating part (5) limiting the filter housing (1) at an end. The housing terminating part (5) forms an element receiving device having a fluid passage (43) concentric to the longitudinal axis (3). The fluid passage has inner screwing elements (41). A connecting piece (31) of the end cap (21) is able to be screwed into the passage using outer screwing elements (33). The sealing device has a sealing element (38) that is combined with the end cap (21) to form a cohesive component and that is accommodated in a seat (37) configured at the transition between the end cap (21) and the adjacent beginning of the thread turns (39) of the screwing elements (33) positioned at the connecting piece (31).
US08419936B2 Low noise back pressure regulator for supercritical fluid chromatography
A drive mechanism for back pressure regulator used in liquid chromatography, supercritical fluid chromatography, or supercritical fluid extraction allows very fine automated control over a very wide range of pressures by combining a linear actuator compressing a spring, pushing a pin. The nozzle assembly of the regulator comprises a flow through chamber containing a diaphragm and a seat, in which the pin pushes the diaphragm against the seat, together with an upstream pressure sensor and electronic feedback control to the motor of the actuator. The BPR of the embodiments exhibits high pressure stability and extremely low pressure noise, even at moderate to high pressures. The exemplary BPR can be use at either constant pressure or to generate pressure programs where the pressure is varied versus time. Further, the nozzle assembly has a field-replaceable head, requiring no mechanical adjustment on replacement.
US08419934B1 Filter
A filter assembly includes an outer filter assembly, the outer filter assembly including an outer filter layer of pleated polyester fabric arranged in a hollow cylindrical shape and first and second end caps for retaining the ends of the outer filter layer, and an inner filter assembly including a hollow cylindrical core having a side wall with a plurality of perforations defined therein, an inner filter layer of meltblown polypropylene disposed around an outer surface of the side wall of the hollow cylindrical core, and first and second end caps. The inner filter assembly is removably received within the outer filter assembly such that the hollow cylindrical core and inner filter layer extend within the hollow cylindrical shape defined by the outer filter layer. The filter assembly is adapted to be mounted in a horizontal orientation within a filtering chamber of a spa device.
US08419931B2 Silicone free anti-foaming process and controlled foaming process for petroleum coking
The current invention provides an improved petroleum coking process wherein the risk of silicone poisoning of units downstream of the coke drums is eliminated. The method of the current invention controls the foam layer within the coke drum by injection of a non-silicone anti-foam agent, preferably a tire oil. In another embodiment, the current invention provides a controlled foaming method which increases the liquid production from the coke drum. In the controlled foaming method, an anti-foam agent is cyclically injected into the drum early in the coke drum fill cycle. The cyclic injections manage the foam layer without inducing the induction phase in the coke feedstock, thereby increasing the total volume of feedstock received by the coke drum.
US08419928B2 Hydrocarbon fuel oil for use in fuel cell system
Hydrocarbon fuel oil with paraffins as the main constituent for use in fuel cell systems is provided having (1) paraffins of less than 13 carbons constitute not less than 60% by mass; (2) isoparaffins of 15 or more carbons constitute from 0.01 to 9% by mass; and (3) normal paraffins of 13 or more carbons constitute not more than 2% by mass. Also, in addition to the aforementioned compositions (1) to (3), it is preferable if isoparaffins of 17 or more carbons constitute not more than 3% by mass.
US08419918B2 Method of surface modification of polyimide film using ethyleneimines coupling agent, manufacturing method of flexible copper clad laminate and its product thereby
A method of surface modifying a polyimide film, a method of manufacturing a flexible copper clad laminate using the same, and a flexible copper clad laminate (FCCL) having a two-layer structure manufactured thereby. The method of surface modifying a polyimide film is conducted by modifying the surface of a polyimide film through a first plasma treatment, dipping the polyimide film into a solution containing an ethyleneimine-based silane coupling agent prepared by mixing the compound of Formula 1 and the compound of Formula 2 at a molar ratio of with 0.25˜1, and then modifying the surface of the polyimide film through a second plasma treatment. The method of surface modifying a polyimide film is advantageous because it may be substituted for a conventional surface treatment processes using ion beams. Also, the FCCL having a two-layer structure, formed by conducting copper sputtering and electroplating on the surface modified polyimide film, has good adhesive strength between the polyimide film and the copper foil and can maintain such adhesive strength even at high temperatures for a long period of time. Further, it may be usefully applied to electronic parts, such as flexible printed circuit boards, TCP (Tape Carrier Package), COF (Chip On Film), etc.
US08419916B2 Biological molecule separation apparatus
A biological molecule separation apparatus for separating a biological molecule of one embodiment of the present invention has a buffer solution chamber receiving a buffer solution, a separation electrode arranged in the buffer solution chamber, a biological molecule separation medium for separating a biological molecule, a biological molecule adsorption film for adsorbing a biological molecule, a pair of transfer electrodes having a plurality of line shaped conductors extending in a direction perpendicular to a first direction, the conductors being arranged in the direction perpendicular to the first direction, and a separation part which holds the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode, wherein the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode are stacked in this order.
US08419915B2 Gas sensor
A gas sensor including a detection element having a stacked structure configured to detect a specified gas component contained in a gas to be detected. The detection element includes: a sensing portion including one or more solid electrolyte layers containing a first material as a main component and having a first surface and a second surface opposite the first surface; a first portion stacked on the first surface and including one or more first base layers containing a second material as a main component different from the first material; and a second portion stacked on the second surface and including one or more second base layers containing the second material. A total thickness of the one or more second base layers in a stacking direction is not less than 80% but not more than 120% of a total thickness of the one or more first base layers.
US08419914B2 Potentiometric sensors based on anionic boron clusters
Potentiometric sensor comprising an ion selective electrode and the latter, on its part, containing a membrane characterized in that it comprises: a thermoplastic material; an electroactive substance based on a salt wherein the cation is the protonated form of the analyte to be determined and the anion is a cluster which comprises boron atoms; and a plasticizing agent. In addition, the invention further relates to the use of said sensor for the detection and/or quantification of a compound containing at least one nitrogen atom.
US08419908B2 Electrolytic apparatus for producing fluorine or nitrogen trifluoride
It is a task of the present invention to provide an electrolytic apparatus for producing fluorine or nitrogen trifluoride by electrolyzing a hydrogen fluoride-containing molten salt, the electrolytic apparatus being advantageous in that the electrolysis can be performed without the occurrence of the anode effect even at a high current density and without the occurrence of an anodic dissolution. In the present invention, this task has been accomplished by an electrolytic apparatus for producing fluorine or nitrogen trifluoride by electrolyzing a hydrogen fluoride-containing molten salt at an applied current density of from 1 to 1,000 A/dm2, the electrolytic apparatus using a conductive diamond-coated electrode as an anode.
US08419902B2 Method and system for wasteless processing and complete utilization of municipal and domestic wastes
Proposed are a system and method for wasteless pyrolytic processing and complete utilization of municipal and domestic wastes. The wastes are sequentially passed through units of sorting, grinding, drying, accumulating, and sending to a pyrolysis reactor for pyrolytic treatment. The syngas produced in the pyrolysis is passed through dry cleaning, dust catching, a first wet cleaning with water, a second wet cleaning with alkali, and a floatation unit for separation of water which is purified to an extent sufficient for technical use. The purified syngas is also passed through an absorber and is then used as a working medium for a power generation unit such as a gas turbine co-generator that generates electricity. Solid products of the pyrolysis reaction, such as coke, are returned to the reactor for afterburning, and the heat of the reaction can be utilized in a dryer, or the like.
US08419901B2 Closed retort charcoal reactor system
A reactor is provided for converting organic material to charcoal, with the reactor having a furnace and a retort extending through the furnace. The retort has an auger extending therethrough, with the auger having a flight with gaps therein. Members project inwardly from the walls of the retort at the gaps in the flight to unplug blockages in the retort. A gas collection system is provided which has a branched portion having two or more venting tubes, each with valves so that each may be shut off independently to allow to off-line cleaning without requiring shutdown of the system. A method for converting organic material may be practised by introducing combustible materials into the reactor.
US08419898B2 Wet strength resins derived from renewable resources
The present invention relates to cationic polymers, such as polyaminoamide epichlorohydrin (PAE), that are derived from renewable resources and can be used to produce wet strength resins suitable for a variety of applications, such as in absorbent paper articles.
US08419891B2 Semiconductor development apparatus and method using same
A knife edge ring apparatus is provided for use during semiconductor manufacturing which includes a ring-shaped body having an inner side wall, an outer side wall and a top surface having a predetermined width. A multi-staged inclined portion is formed in the outer side wall and a plurality of discharge holes penetrate the body. Each of the discharge holes have an inlet associated therewith positioned at the inclined portion. The knife edge ring allows developer and cleaning solution to be discharged away from the wafer. A method of cleaning the bottom surface of a semiconductor wafer is also provided which employs the use of the knife edge ring. Developer is supplied onto the top surface of a wafer. Spraying solution is sprayed onto the bottom surface of the wafer. The knife edge ring guides the developer and the cleaning solution remaining on the bottom surface of the wafer's edge along an inclined portion formed at an outer side wall of the knife edge ring and causes the developer and the cleaning solution to flow into a plurality of discharge holes.
US08419886B2 Method of manufacturing composite parts
A method of manufacturing two or more composite parts, the method comprising: assembling the composite parts on a mandrel by laying a series of layers of bands of composite material onto the mandrel with a placement machine,—rotating the mandrel as the bands are laid onto the mandrel; attaching two or more debulk frames (10, 11) to the mandrel between opposed edges of the composite parts after the composite parts have been assembled; wrapping the mandrel, debulk frames (10, 11) and composite parts in a debulk bag; heating the composite parts,—forming a vacuum between the mandrel and the debulk bag so that the debulk bag is sucked into voids between the debulk frames and the heated composite parts and progressively presses against the heated composite parts whereby excess material is squeezed by the debulk bag towards their opposed edges; and removing the debulk bag and the composite parts from the mandrel.
US08419885B2 Method of bonding carbon nanotubes
A method to bond carbon nanotubes to a surface. The mechanism of this bonding is studied, and shows that intercalation of alkali ions is possibly the central mechanism. Bonding pull-off forces of 4-5 N/cm2 were measured. This bonding also provides improved interfacial properties for other phenomenon, including improved thermal conductivity.
US08419883B2 Fiber reinforced composite cores and panels
A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips, and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins. Continuously wound strips or strip sections may be continuously fed either longitudinally or laterally into molding apparatus which may receive skin materials to form reinforced composite panels.
US08419879B2 Method and apparatus for combining two flat products with adhesive
A method for combining with adhesive at least two flat products positioned at least partially one above the other is provided. The method includes moving first flat products in an overlapping flow along a guiding line in a conveying direction and separating the first flat products into a non-overlapping flow after leaving the guiding line and while being conveyed through an underneath-arranged conveying region. The method also includes supplying second flat products from underneath the first flat products with a synchronous time relative to the first flat products. The second flat products each have an adhesive surface. The method further includes combining a respective one of the first flat products along the adhesive covered surface of an underneath supplied respective one of the second flat products.
US08419875B2 Method of manufacturing a curved structural element made of composite material and having a complex, open cross-section
A method of manufacturing a curved structural element made of composite material has a complex, open cross-section the structural element is formed by the assembly of components made of composite material. A plurality of flat, fresh components are prepared, each component being constituted by a flat layer of curved fibres previously infused with resin, combined with a pre-impregnated layer with straight fibres. Hot-forming of the flat, raw components is then performed. The hot-formed, fresh components are then assembled in accordance with a predetermined sequence on a polymerization tool. The tool includes a shaped, inflatable device astride which a C-shaped raw component is deposited. Finally, the fresh components assembled on the tool are subjected to a polymerization cycle in an autoclave. The inflatable device is inflated by the pressure produced in the autoclave to apply a predetermined pressure from the inside of the C-shaped fresh component.
US08419873B2 Tire building method and rubber strip bonding apparatus
The invention can surely accomplish lamination without the generation of voids in building a tire constructed to comprise a plurality of rubber members for a tire when a ribbon-shaped rubber strip (R) is spirally wound and laminated, and uses holding rolls (30) and two sets of stitching rolls (40a), (40b) arranged in parallel with a center of a rubber strip width (W) therebetween to enable performing of an independent pressing motion, such that the rubber strip (R) is pressed and bonded by the holding rolls (30) in a position, in which the rubber strip (R) is wound, and the stitching roll (40a) or (40b) positioned fore in an advancing direction of traverse movement, out of the two sets, is caused to perform a pressing motion in a regional part just after the press whereby a fore part of the rubber strip in the advancing direction is pressed and bonded.
US08419869B1 Method of producing classes of non-stainless steels with high strength and high ductility
The present disclosure is directed and formulations and methods to provide non-stainless steel alloys having relative high strength and ductility. The alloys may be provided in sheet or pressed form and characterized by their particular alloy chemistries and identifiable crystalline grain size morphology. The alloys are such that they include boride pinning phases. In what is termed a Class 1 Steel the alloys indicate tensile strengths of 630 MPa to 1100 MPa and elongations of 10-40%. Class 2 Steel indicates tensile strengths of 875 MPa to 1590 MPa and elongations of 5-30%. Class 3 Steel indicates tensile strengths of 1000 MPa to 1750 MPa and elongations of 0.5-15%.
US08419868B2 Process and method to increase the hardness of Fe-Cr-C weld overlay alloy
A method of preparing a mechanical component with an Fe—Cr—C hardfacing weld overlay alloy for improving the resistance of the mechanical component to abrasion, erosion or erosion/corrosion for use in very abrasive, erosion or erosive/corrosive environments by significantly increasing the hardness of the weld overlay is disclosed. To improve the resistance to abrasion, erosion or corrosion, a weld overlay of a Fe—Cr—C hardfacing alloy is applied onto the surface of a metallic component, such as tubes, pipes, or vessels. Welding and cladding methods including gas-metal-arc welding (GMAW), gas-tungsten-arc welding (GTAW), and laser cladding may be utilized. Then, the component is heat-treated at elevated temperatures for a sufficient time, resulting in additional hardening and thus further increasing the weld overlay's resistance to abrasion, erosion, or erosion/corrosion.
US08419855B2 Substrate processing chamber with off-center gas delivery funnel
Methods and apparatus for processing substrates are disclosed herein. The process chamber includes a chamber body, a substrate support pedestal, a pump port and a gas injection funnel. The chamber body has an inner volume and the substrate support pedestal is disposed in the inner volume of the chamber body. The pump port is coupled to the inner volume and is disposed off-center from a central axis of the substrate support pedestal. The pump port provides azimuthally non-uniform pumping proximate to a surface of the substrate support pedestal and creates localized regions of high pressure and low pressure within the inner volume during use. The gas injection funnel is disposed in a ceiling of the chamber body and opposite the substrate support pedestal. The gas injection funnel is offset from the central axis of the substrate support pedestal and is disposed in a region of low pressure.
US08419854B2 Film-forming apparatus
In a film-forming apparatus in which two or more gases are used, a uniform film is formed. In a film-forming apparatus provided with a film-forming chamber and a shower head, the shower head is provided with a material gas diffusion chamber and a reactive gas diffusion chamber. A gas passage which communicates the material gas diffusion chamber and a material gas introduction pipe is constituted into multi-stages of one stage or more. Each stage has a gas passage represented by 2n-1 (where n is the number of stages). The first-stage gas passage has connected to the center thereof the material gas introduction pipe. Each of second-stage and subsequent-stage gas passages has connected to the center thereof connection holes which are provided on both ends of the previous-stage gas passages so as to be in communication with the previous-stage gas passages. Each of the final-stage gas passages is connected to the material gas diffusion chamber by connection holes formed on both ends of each of the gas passages.
US08419852B2 Light-weight composition and mix for masonry, mortar and stucco
An application for a pre-mixed mortar, stucco or masonry composition includes a approximately 75% sand and 25% of a light-weight cement mix comprising a cement (either Portland cement or Gypsum), ground granulated blast furnace slag, sodium tall oil, sodium stearate, sodium C14-16 Alpha Olefin, linear alkyl benzene; and silicon dioxide.
US08419849B2 Disazo dyes and their use in ink-jet printing
A compound of Formula (1) or a salt thereof: wherein: X is N or C(CN); Z is optionally substituted naphthyl; Ar is an aryl group carrying at least one substituent selected from the group consisting of an acetyl group, an acetate ester group, an amide group, a sulfonamide group, a sulfoxide group, a sulfone group, a phosphonate group, a nitrile group, an isonitrile group, a quaternary amine, a carbonyl group (other than a carboxylic acid), a polyhaloalkyl group or a halogen atom; and Ar may optionally be substituted with one or more further substituents.
US08419848B2 Disazo compounds and their use in ink-jet printing
A compound of Formula (1) or a salt thereof: wherein: X is N or C(CN); Z is optionally substituted naphthyl; and Ar is an aryl group carrying at least one nitro substituent and optionally one or more further substituents.
US08419846B2 Erasable inkjet ink
According to one embodiment, an erasable inkjet ink includes a leuco dye, a non-water-soluble developer, and a solvent containing an alcohol and water. The amount of the water is 7 to 25% by mass of the solvent.
US08419844B1 Mist/moisture removal using fixed bed trickle columns
A moisture removal system for removing water moisture from an air stream and an associated method are provided. The moisture removal system includes one or more packed beds that include a water-entry surface at which liquid water is received and an air-entry surface that is located substantially opposite the water-entry surface and at which the air stream is received. The air stream passes through the one or more packed beds in a direction substantially counter-current to the passage of the liquid water and the liquid water and the air stream contact one another in the one or more packed beds resulting in the removal of at least a portion of the water moisture from the air stream. The moisture removal system can be located upstream of and be operably connected to the inlet of a gas turbine system to which the air stream is delivered from the moisture removal system.
US08419842B2 Hydronic system air eliminator
An air eliminator including a housing having first and second portions, the housing defining: a chamber, an inlet in fluid communication with the chamber; an outlet in fluid communication with the chamber; and an axis extending from the first portion to the second portion, a float assembly connected to the first portion of the chamber for releasing air from the chamber, and degassing disks stacked within the chamber along an axis, wherein each disk includes a plurality of rings such that the degassing disks cause micro gas pockets in water passing through the chamber to combine into relatively large and buoyant air pockets that collect and pass along the axis to the float assembly for release.
US08419839B2 Porous polytetrafluoroethylene membrane, method for producing the same, and water-proof air permeable filter
First, a first porous body is manufactured by stretching, in a uniaxial direction, a sheet made of polytetrafluoroethylene having a standard specific gravity of 2.155 or more, and a second porous body is manufactured by stretching, in biaxial directions, a sheet made of polytetrafluoroethylene. Next, the first porous body is integrated with the second porous body by stretching a laminate of the first porous body and the second porous body in the same direction as the uniaxial direction while heating the laminate at a temperature equal to or higher than a melting point of polytetrafluoroethylene. Thus, a porous polytetrafluoroethylene membrane is produced.
US08419835B2 Apparatuses and methods for gas-solid separations using cyclones
Cyclones for gas-solid separators are described, which are especially applicable for use in a downflowing third stage separator (TSS) for the removal of dust particles, such as solid catalyst fines, from the flue gas streams exiting the catalyst regenerator in fluid catalytic cracking (FCC) processes. A number of important flow characteristics result from the configuration of the cyclones, particularly with respect to the relative axial lengths over which swirl vanes and central hubs of the cyclones extend. These characteristics include a decrease in growth of turbulent eddies that conventionally result from a sudden expansion, in open cross-sectional area, of gas exiting swirl vanes.
US08419829B2 Method and system for treating Fishcher-Tropsch reactor tail gas
A method and system for coal-to-liquids (CTL) conversion is provided. The system includes a coal gasifier configured to partially oxidize a coal fuel stream to generate a flow of synthesis gas (syngas), a Fischer-Tropsch (FT) reactor configured to receive the flow of syngas and to generate a stream of tail gas, and an absorber coupled in flow communication downstream of the FT reactor and configured to receive the stream of tail gas. The absorber is further configured to generate a first flow including carbon dioxide, C2 hydrocarbons, and higher boiling gas components (C3+) and a second flow including C1, carbon monoxide, hydrogen, and nitrogen. The system also includes a first membrane separator including a selective membrane configured to separate the second flow from the absorber generating a permeate flow of hydrogen and a non-permeate flow of combustion turbine fuel gas including methane and hydrogen.
US08419828B2 Multi-stage membrane separation process
The invention concerns a process for the removal of gaseous acidic contaminants, especially carbon dioxide and/or hydrogen sulphide, in two or more stages from a gaseous hydrocarbonaceous feedstream (1) comprising hydrocarbons and said acidic contaminants, using one or more membranes in each separation stages. The gaseous hydrocarbonaceous feedstream is especially a natural gas stream. The process is especially suitable for feedstreams comprising very high amounts of acidic contaminants, especially carbon dioxide, e.g. more than 25 vol. %, or even more than 45 vol. %. In a first stage (2) a pure or almost pure stream of acidic contaminants is separated from the feedstream, the acidic contaminants (4) stream suitably containing less than 5 vol % of hydrocarbons. The remaining stream (3) comprises the hydrocarbons and still a certain amount of gaseous acidic contaminants. In a second stage (5) a pure or almost pure stream of hydrocarbons (8) is separated from the remaining stream, where after the then remaining stream (6) is combined with the feed for the first stage (1), the hydrocarbon stream suitably containing less than 5 vol % of acidic contaminants.
US08419822B2 Methods for producing carboxylic acid stabilized silver nanoparticles
Processes for producing carboxylic acid-stabilized silver nanoparticles are disclosed. A reaction mixture comprising a silver salt, a carboxylic acid, and a tertiary amine is heated to form carboxylic acid-stabilized silver nanoparticles.
US08419819B2 Solid urea fertilizer
A solid urea fertilizer prepared by mixing a solid, flowable, urea formaldehyde polymer with a urea source, such as molten or solid urea to form a fertilizer that has favorable crush strength characteristics, low biuret content, and/or desirable storage and handling properties. The urea fertilizer may contain additionally, an aqueous urea formaldehyde solution or mixture. Optionally, the fertilizer may contain a urease inhibitor and/or a nitrification inhibitor.
US08419818B2 Protective device for an air filter, in particular of a generating set, comprising portions to assemble radially on the filter
A protective device is provided for an air filter that is substantially cylindrical and is intended to equip in particular a generating set. The filter is intended to be press fitted to a duct of said set. The protective device includes at least two portions that are securable radially on the filter in order to form a protective case surrounding the filter.
US08419810B2 Method for producing biofuels, transforming triglycerides into at least two biofuel families: fatty acid monoesters and ethers and/or soluble glycerol acetals
A process for producing biofuels by transforming triglycerides into at least two families of biofuels, monoesters of fatty acids and soluble ethers and/or acetals of glycerol, comprises: at least one transesterification step in which said triglyceride is reacted by heterogeneous catalysis with at least one primary monoalcohol selected from methanol and ethanol to produce at least one methyl and/or ethyl ester of the fatty acids of the starting triglycerides and glycerol, said products being free of by-products; and an etherification step in which the glycerol is reacted with at least one olefinic hydrocarbon containing 4 to 12 carbon atoms; and/or an acetalization step in which the glycerol is reacted with at least one compound selected from aldehydes, ketones and acetals derived from aldehydes or ketones.
US08419805B2 Silicone liner unit used for prosthetic limbs
A silicone liner unit used for prosthetic limbs includes a silicone liner portion, a smooth outer layer, an inner layer and an innermost layer. The silicone liner portion is made of silicone elastomer liner and has an open end. The smooth outer layer is made of Hl a-methyl-Disilane or a compound containing poly-p-xylene and may have a slightly protrusive pattern on its outer surface. The inner layer is made of fibrous tissue and is flexible. The innermost layer is disposed on top of the inner layer and is made of silicone elastomer liner to enhance the strength of the improved silicone liner unit. The smooth outer layer allows the improved silicone liner unit to be put on and taken off easily.
US08419803B2 Calcium phosphate cements and methods for using the same
Methods and compositions for producing flowable compositions, e.g. pastes, that set into calcium phosphate products are provided. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with a setting fluid to produce the flowable composition. A feature of the subject methods is that the dry reactants include a particulate calcium and/or phosphate reactant having a mean particle size of less than about 8 μm and narrow size distribution. Also provided are the compositions themselves as well as kits for use in practicing the subject methods. The subject methods and compositions produced thereby find use in a variety of applications, including the repair of hard tissue defects, e.g., bone defects.
US08419802B2 Devices and methods for treating defects in the tissue of a living being
An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be “matched” to provide the implant with similar physical and/or chemical properties as the host tissue.
US08419798B2 Joint prosthesis with infinitely positionable head
A joint prosthesis includes a head component that is engaged to a bone stem through a mounting element. The mounting element is configured for articulating engagement with the stem to permit angular positioning of the head component in multiple degrees of freedom. The mounting element is fastened to the stem by a press-fit engagement and a separate mechanical fastener.
US08419797B2 Implant for stabilizing bones or vertebrae
An implant for stabilizing bones or vertebrae includes an implant body with at least a first hole and a second hole that can be fixed by a first screw and a second screw. Each of the screws includes a screw thread. Each of the holes has a threaded portion with an internal thread for cooperating with the screw thread, wherein the threaded portion of at least the first hole is formed of a flexible material. A guiding member that is a separate part is insertable into the implant body such that it is arranged at least partially within the first hole. The guiding member is configured to guide the first screw when the first screw is screwed through the threaded portion of the first hole. The second screw is spaced apart from the guiding member when the second screw is screwed through the threaded portion of the second hole.
US08419783B2 Graft deployment assist tool
A delivery system for a medical device may include a sheath, a catheter slideably disposed within the sheath, and a hemostatic device comprising a housing disposed around and sealingly engaged with the sheath by a first seal. A sleeve is slideably coupled to the catheter and comprises a second seal sealingly engaging the catheter. The sleeve is movable between a first position, in which the sleeve is disposed outside of the housing and the first seal is sealingly engaged with an outer surface of the catheter, and a second position in which at least a portion of the sleeve is disposed within the housing between an inner surface of the housing and the outer surface of the catheter, wherein, in the second position, the first seal is sealingly engaged with an outer surface of the sleeve and the second seal is sealingly engaged with the outer surface of the catheter.
US08419781B2 Fluorescent handpiece
A handpiece can treat biological tissue using electromagnetic radiation, which can be substantially fluorescent light. The handpiece includes a source of electromagnetic radiation and a waveguide. The waveguide is adjacent the source, receives electromagnetic radiation from the source, and delivers the electromagnetic radiation to the biological tissue. The handpiece also includes a system for circulating a fluorescent substance through the waveguide. The fluorescent substance is capable of modulating at least one property of the electromagnetic radiation.
US08419777B2 Bone plate screw-blocking systems and methods
A bone plate screw-blocking system and method that comprises a plate with at least two bone screw receiving holes, blocking elements, bone screws, and a tool capable of simultaneously actuating at least two blocking elements. The plate includes an upper surface and a lower surface with bone screw receiving holes that extend through both surfaces of the plate. The bone screws couple the plate to the bone via the bone screw receiving holes. The blocking elements are movably positioned proximate each bone screw receiving hole. In an initial unblocked position, the blocking elements do not cover the bone screw receiving holes. Upon movement into final blocked positions, the blocking elements cover at least a portion of the bone screw receiving holes and preferably extend over at least a portion of the bone screw during use.
US08419773B2 Stabilization device for stabilizing bones of a vertebra and rod connector used therefor
A stabilization device for stabilizing bones of a vertebra includes a first rod, a second rod, a rod connector connecting the first rod and the second rod, the rod connector comprising a receiving portion for receiving the first rod and a fixation element for fixing the first rod in the receiving portion, wherein in the receiving portion a rod contacting surface is provided and wherein the contour of this rod contacting surface has deviations from the contour of the surface of the first rod. The rod connector allows to connect a flexible rod, for example made of an elastomer material, with a rigid rod, made for example of a metal.
US08419772B2 Systems, methods and devices for correcting spinal deformities
Provided herein are systems, devices and methods for the correction of spinal deformities with the use one or more implantable rods configured to apply a corrective force to the spine. Methods of minimally invasive implantation of a corrective system are provided, such as where the corrective system is attached only to the spinous process of one or more vertebral bodies. Various corrective systems as well as components thereof are also provided, such as those that allow limited movement with respect to the spinal column.
US08419770B2 Spinal facet implants with mating articulating bearing surface and methods of use
Superior and/or inferior facets of one or more facet joints may be replaced by superior and/or inferior facet joint prostheses. In one embodiment, a kit of superior or inferior prostheses is provided, in which the prostheses have at least two dimensions that vary among members of the kit independently of each other. Each prosthesis may have a bone engaging surface having a surface that is polyaxially rotatable against a corresponding resection of a vertebra. Each prosthesis may also have an articulating surface shaped such that, after attachment to the spine, the replaced or partially replaced facet joints provide a larger medial-lateral range of motion when the spine is flexed than when the spine is extended. Crosslinks may be used to connect left and right prosthesis together in such a manner that they are stabilized in a position in which they are seated directly against the vertebra.
US08419766B2 Medical device actuators
The present invention provides a flexible actuator, and methods for manufacturing and using a flexible actuator, for transmitting high loads from a user to an end effector. In one exemplary embodiment, the flexible actuator can extend from a handle of a medical device to an end effector located on a distal end of the device. The actuator can include a head formed on a terminal end thereof with at least one planar surface that is approximately coplanar with an outer surface of the flexible actuator. In use, the actuator can be coupled to a medical device having an end effector located on a distal end thereof. Tension applied to the actuator can be effective to actuate the end effector.
US08419764B2 Surgical puncture access
A surgical device mitigates over-puncture with a bias spring that biases a leading, cutting edge in the opposite direction of the anticipated over-puncture. An associated locking mechanism is configured to release the force of the bias spring in a direction counter to the direction of insertion when the tension force of tissue against the cutting edge is released. Thus, when an opening in the tissue forms, the tension is released and the cutting edge can move opposite to the direction of insertion of the surgical device at the same time that an applied force drives the instrument in the direction of insertion. In this manner, the spring and locking mechanism cooperate to move the cutting edge opposite to the direction of insertion as soon as an incision is made.
US08419763B2 Safety needle for accessing the interior of a hip joint
A safety needle comprising a handle; a hollow needle; a trigger carriage; an obturator; a spring; a trigger; a first latch and a second latch; the first latch, second latch and trigger being configured so that when the trigger carriage is in a distal position and the first latch set, and the trigger is thereafter pulled proximally, the first latch is released and the trigger carriage moves proximally into a proximal position, and thereafter releasing the trigger causes the trigger carriage to move into an intermediate position and set the second latch; and further wherein, when the trigger carriage is in its intermediate position and the distal end of the obturator engages tissue, the trigger carriage is moved proximally so as to release the second latch.
US08419757B2 Cordless hand-held ultrasonic cautery cutting device
An ultrasonic surgical assembly includes a reusable cordless ultrasonic transducer and a disposable handle body that defines a battery-holding compartment therewithin, having an ultrasonic surgical waveguide, and operable to removably couple the transducer to the waveguide, the transducer being removably couplable to the handle body.
US08419752B2 Endoscopic surgical clip applier with connector plate
An apparatus for application of surgical clips to body tissue is provided and includes a handle assembly; a shaft assembly including a housing extending distally from the handle assembly and defining a longitudinal axis; a plurality of surgical clips disposed within the shaft assembly; a jaw mounted adjacent a distal end portion of the shaft assembly, the jaw being movable between an open spaced-apart condition and a closed approximated condition; and a pusher bar reciprocally disposed within the housing of the shaft assembly and being detachably connectable to the housing of the shaft assembly, the pusher bar being configured to load a distal-most surgical clip into the jaws during distal movement and remain connected to the housing of the shaft assembly and in a distally advanced position during an approximation of the jaws.
US08419748B2 Helical thrombus removal device
A device for removing thrombus from a body cavity is disclosed. The device comprises a flexible wire having a proximal end and a distal end. The device further comprises an elongated shaft having a proximal portion and a distal portion. The proximal portion attached to the distal end of the flexible wire and distally extends therefrom to the distal portion. The device further comprises an expandable member formed helically about the elongated shaft. The expandable member is configured to helically close, defining a collapsed state for delivery and retrieval of the device. The expandable member is configured to helically open, defining an expanded state for removing thrombus from the body cavity. The expandable member has at least one member portion helically extending from the elongated shaft at a predetermined angle, defining a proximally faced opening when the member is in the expanded state.
US08419747B2 Link systems and articulation mechanisms for remote manipulation of surgical or diagnostic tools
Articulating mechanisms, link systems, and components thereof, useful for a variety of purposes including, but not limited to, the remote manipulation of instruments such as surgical or diagnostic instruments or tools are provided. The link systems include links wherein at least two adjacent links are pivotable relative to one another around two distinct pivot points. Mechanisms for locking the links are also provided.
US08419746B2 Exploration device to monitor the penetration of an instrument in an anatomic structure
An exploration device to monitor the penetration of an instrument in an anatomic structure including at least two electrodes; a source of voltage supplying the at least two electrodes; a means for measuring impedance between the electrodes; a means of angular location formed by at least one electrode punctually coinciding with a peripheral surface of the penetration instrument, the coinciding surface of the electrode having a position set off from a longitudinal axis the instrument; and means for detecting a position of the at least one electrode.
US08419745B2 Bone plate bender system
A pair of plate benders are provided for bending a bone plate. Each bender includes a lever arm having a first end and a second end. The first end includes a fulcrum for placement on the upper surface of the plate, and a foot insertable through the oblong screw hole to contact the lower surface of the plate. The second end includes a cut-out with a central divider. The cut-out has a length dimensioned to extend widthwise about the plate at the location of the oblong screw hole with the divider extending into the oblong screw hole for stability. The second end may also be provided with a deep slot that accommodates the thickness of the plate. In use, plate benders with such structure can be used in pairs to longitudinal bend the plate; bend the plate in plane; or twist the plate along its axis.
US08419740B2 Customized patient-specific bone cutting instrumentation
A number of orthopaedic surgical instruments are also disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
US08419732B2 Method for using a fixator device
A method for determining the proper configuration of a fixator or other medical device to correct a given deformity by solving the simultaneous equations representing the kinematic chain for the device. One skilled in the art would appreciate that x-rays, clinical evaluations, or a combination of both may be used to determine the distal and proximal mounting characteristics, including the use of digital x-rays with images from an imaging device to reduce or eliminate the needs for a physician to take measurements. The technique can be expanded to other medical evaluations. Additionally, one skilled in the art would appreciate that the method of the present invention could be written as one or more sets of instructions stored on a computer-readable medium that could be executed by a computer.
US08419730B2 Systems and methods for navigating an instrument through bone
System and methods are shown having a tube-within-tube assembly with a deployable curved deflectable tube or cannula that deploys from a straight cannula or trocar. The curved cannula has pre-curved distal end to create an angular range of 0° to 180° when fully deployed from the straight trocar. The curve is configured such that the flexible element carrying a treatment device can navigate through the angular range of deployment of the curved cannula. The curved cannula allows the flexible element to navigate through a curve within bone without veering off towards an unintended direction.
US08419729B2 Cardiac ablation devices and methods
Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. The devices and methods are used to ablate epicardial tissue in the vicinity of the pulmonary veins, and other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient utilizing minimally invasive introducer devices and the like. A preferred embodiment of the introducer device includes an integrated light source that can be activated at the time of use.
US08419721B2 Optical system for ophthalmic surgical laser
A laser system for ophthalmic surgery includes a laser source to generate a pulsed laser beam, an XY scanner to receive the pulsed laser beam and to output an XY-scanning beam, scanned in two directions transverse to a Z direction, a Z scanner in a scanner housing to receive the XY-scanning beam and to output an XYZ-scanning beam scanned additionally in the Z direction, a mirror to deflect the XYZ-scanning beam received from the Z scanner, and an objective, in an objective housing, to receive the deflected XYZ-scanning beam and to focus the received XYZ-scanning beam onto a target region, wherein the scanner housing is separate from the objective housing.
US08419720B1 Flexible laparoscopic device
A laparoscopic device that includes an outer rod having a end connected to a handle and an end having an articulated section formed from links joined with non-diametrical hinges; an actuation rod within the outer rod, having an end connected to the handle and an end connected to a tension element within the articulated section, configured to cause the articulated section to bend when tension is applied; and an attachment rod within the actuation rod having an end connected to the handle and an end having a flexible section connected to a tool. The handle includes an actuator configured to apply tension to the attachment rod such that the tool is activated; a rod actuator configured to apply tension to the actuation rod such that the articulated section of the outer rod bends; and a lockable rotator, configured to rotate the outer rod with respect to the handle.
US08419714B2 Flexible low compliance extension tubing for balloon inflation
A controlled volume inflation-deflation device to inflate a balloon to occlude a blood vessel by dialing a knob that locks at rotational positions to locate a plunger at equally spaced locations within a syringe of the inflation-deflation device. The inflation-deflation device includes a releasable latch to lock the proximal and distal housings together to hold the plunger forward for occlusion, and to separate and hold the proximal and distal housings to retract the plunger for perfusion. When the inflation-deflation device is returned to the latched position, the balloon is re-inflated to its previous occlusive diameter. Also, an extension tube made of a lower modulus outer material co-extruded over and miscible with a higher modulus inner material may be used to produce a suitably low compliance extension tube for the inflation-deflation device. The balloon may have tapered ends and a cylindrical center portion so that it increases by more equal increments in outer diameter in response to incremental equal increases in inflation volume.
US08419710B2 Methods for infusing fluids via an implantable infusion system
Methods for delivering first and second fluid compositions to a target location of a subject include delivering the first composition from reservoir of an implantable infusion pump and delivering the second composition through a catheter access port of the implantable infusion device. The access port and reservoir are fluidly coupled to a catheter having a delivery region implanted in the target region. The methods more fully realize the therapeutic potential of infusion devices having both an access port and a reservoir. Strategic use of different agents that compliment the function of each other delivered via either the access port or the reservoir can result in enhanced therapeutic potential.
US08419707B2 Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more substrates configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to detect one or more physiological conditions of the one or more joints; and one or more microjet applicators supported by the one or more substrates and configured to respond to the one or more sensors by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.
US08419702B2 Disposable diaper provided with tape fastener
The present invention aims to improve the tape fasteners provided on the diaper chassis so that the upper outside regions of the wearer's thighs should not be irritated by the edges of the tape fasteners. A lower edge of a first section in each tape fastener extends so that a space is defined between this lower edge and an imaginary extension of a lower edge of a second section in the tape fastener.
US08419696B2 System and method for delivering reduced pressure to subcutaneous tissue
A reduced pressure treatment system includes a first fluid pathway in communication with a reduced pressure source and a second fluid pathway. The system includes a reduced pressure manifold having a substantially gas impermeable barrier and at least one outer conduit defining a lateral edge of an interior region. The outer conduit and the substantially gas impermeable barrier enclose a portion of the interior region. The outer conduit is in fluid communication with one of the first and second fluid pathways. The outer conduit has at least one opening in fluid communication with the interior region. An inner conduit is at least partially disposed within the interior region and is in fluid communication with another of the first and second fluid pathways. The inner conduit has at least one opening in fluid communication with the interior region.
US08419692B2 Injection device with rotatable dose setting
An injection device comprising a housing and a dose setting mechanism including a dose setting element. Contrary to prior art injection devices, the dose setting element can only be set at a few different dose settings. This is established by forming the dose setting element as a rotatable dish concealed within the housing and having a number of projections projecting outside the boundaries of the housing through a slot in the housing. A dose is set by activating a projection which in addition provides the user with a tactile guidance. Usually one projection is provided for one dose setting limiting the number of doses to be set to the number of projections.
US08419690B2 Medical device with needle safety shielding
In one aspect, a medical device is provided which includes flexible tubing having a distal end and a proximal end and at least a first lumen extending from said distal end to said proximal end; a first needle cannula having proximal and distal ends, said first needle cannula being mounted at said distal end of said tubing and in fluid communication with said lumen; a second needle cannula mounted at said proximal end of said tubing and in fluid communication with said lumen; a shield disposed over said tubing, said shield extending substantially the entire length of said flexible tubing, and said shield being movable relative to said first needle cannula from an initial proximal position wherein said first needle cannula is exposed to a distal position wherein said distal end of said first needle cannula is covered by said shield; and an actuator for actuating the shield at a location spaced from the first needle cannula, preferably closer to the second needle cannula than to the first needle cannula.
US08419683B2 Intraosseous device and methods for accessing bone marrow in the sternum and other target areas
Apparatus and methods are provided to access bone marrow at various target areas. Such apparatus may include an intraosseous device operable to penetrate bone at a selected target area and a depth limiter operable to control depth of penetration of the intraosseous device into bone and associated bone marrow. A manual driver and a guide may be included to optimize optimum insertion of the intraosseous device at a selected insertion site on a sternum.
US08419682B2 Safety syringes
Syringes are disclosed herein incorporating a variety of safety mechanisms for protecting the users from accidental needle stick. In certain embodiments, the syringes incorporate retractable carriages that can be retracted into the syringe barrels by engaging with the plungers. The carriages are configured to receive different needle hubs having any number of needle sizes. In certain other embodiments, the carriages are spring loaded so that as the plungers disengage the carriages from the syringe barrels, the springs automatically retract the needles into the barrels. Still in certain other embodiments, needle hubs with spring loaded needles are used with the syringes. The needles are retracted into the barrels when the plungers activate certain mechanisms incorporated into the hubs to thereby release the needles.
US08419680B2 Rapid exchange pre-dilator
A predilation device may comprise a shaft portion and a distal tip having helical threadings. The predilation device may further include a rapid exchange element rotatably coupled to the shaft portion. A guidewire may slidably engage the rapid exchange element and may guide the predilation device to a lesion site. The predilation device may be positioned with the distal tip abutting the lesion. The shaft portion may be rotated, thereby rotating the tip and causing the tip to pass through the lesion and predilate the lesion. In some embodiments, the tip may remove lesion material.
US08419676B2 Pinch valve mechanism for a medical fluid injection device
In general, this disclosure relates to techniques for sealing, or pinching, high-pressure fluid tubing (e.g., braided tubing) that may be used to deliver medical fluid from a powered medical fluid injection device, such as an injector that delivers contrast media and/or saline during angiographic or computed tomography (CT) procedures. In some cases, one or more low-friction, solenoid-based pinch valve mechanisms may be used. One example powered medical fluid injection device comprises an injector head and at least one pinch valve mechanism that is coupled to the injector head. The at least one pinch valve mechanism comprises a plunger, a reciprocating arm driven by the plunger, and a tube pinching area. The at least one pinch valve mechanism, when deactivated by the injector head, is configured to cause the reciprocating arm to pinch fluid tubing that runs through the tube pinching area.
US08419672B2 Peripheral access devices and systems
A cannulation system for perfusing a patient's circulatory system, includes an inflow cannula having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump, an outflow cannula having a first end adapted to be connected to the blood pump and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension.
US08419671B2 Appliance for cannulation of a blood vessel
The present invention relates to an appliance for cannulation of a blood vessel with a cannula which, after introduction into the vessel, is in fluidic communication with the vessel. At least one means is also provided to permit a controlled division of the blood into a first subsidiary stream which leaves the vessel through the cannula, and a second subsidiary stream which continues to flow through the vessel.
US08419662B2 Hand held massaging tool
A hand held tool 10 has a handle 14, a contact member 16, and an electric motor 12. The contact member has a contact surface portion 17 lying in a first plane. The motor 12 has a stator 23 and an armature 19. The armature 19 is able to move with non-rotary translational motion relative to the stator 23 in a second plane which is parallel to the first plane. One of the stator 23 and the armature 19 is attached to the handle 14, while the other is attached to the contact member 16. Relative motion of the stator 23 and armature 19 imparts relative motion between the handle 14 and the contact member 16. A resilient coupling 18 is coupled between the handle 14 and the contact member 16 and applies a bias against the relative motion between the handle 14 and contact member 16.
US08419659B2 Methods for assessment of improvements in pelvic organ conditions after an interventional procedure
Methods for assessment of pelvic floor conditions based on tactile imaging are described. The vaginal wall is deformed before and after an interventional procedure using a transvaginal probe equipped with tactile pressure sensors and a motion tracking sensor. The vaginal wall coordinates and pressure patterns are obtained during the examination and used to build 3-D tactile image of the vagina and to calculate elasticity modulus profiles and spacing profiles along selected lines inside 3-D tactile image. The “before” and “after” profile values at specified locations are then compared to each other and to thresholds or profiles for normal conditions of vagina and its support structures. Methods of the invention may be used in estimating an improvement after an interventional procedure such as pelvic tissue regeneration, muscle repair or implantation of a supporting structure.
US08419656B2 Post decompression marker introducer system
An apparatus for implanting a locatable marker at a target site within a tissue mass comprises an insertion device and a marker introducer system that is received within the insertion device. The marker introducer system is anchored in a compressed tissue mass and a locatable marker is deployed from the introducer system after the tissue mass is decompressed.
US08419655B2 Method and apparatus for aural acoustic immittance measurement
An acoustic immittance measurement system converts a measure of acoustic immittance (i.e. impedance and/or admittance) of a subject's middle ear to the frequency domain such that variations in magnitude and/or phase are diagnosed using either open-loop or closed-loop measurement techniques.
US08419653B2 Spinal access and neural localization
A method for locating neural tissue in a patient body may involve: advancing a probe along a natural tissue interface between the neural tissue and another tissue in the body, the probe having a first surface oriented toward the neural tissue and a second surface oriented away from the neural tissue; delivering a first electrical current to a first electrode along the first surface of the probe; delivering a second electrical current to a second electrode along the second surface of the probe; and verifying that the first surface of the advanced probe remains oriented toward the neural tissue and the second surface remains oriented away from the neural tissue by monitoring neural response to the first and second electrical currents.
US08419650B2 Downloadable datasets for a patient monitoring system
In general, this disclosure describes techniques for remotely monitoring the health of an ambulatory patient. As described herein, an ambulatory patient may interact with a monitoring device that is located at the patient's home. The monitoring device may prompt the patient to provide responses to health-related questions or requests for physiological characteristics and may upload the responses. A health care professional may then use the responses to evaluate the health of the patient. A set of firmware instructions stored on the monitoring device may cause the monitoring device to perform these functions. These firmware instructions remain the same even when the monitoring device downloads new prompts.
US08419649B2 Vital sign monitor for measuring blood pressure using optical, electrical and pressure waveforms
A method and apparatus for continuous measurement of blood pressure, based on pulse transit time, which does not require any external calibration. This technique, referred to herein as the ‘composite technique’, is carried out with a body-won sensor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of disposable sensors, typically placed on the patient's right arm and chest, connect to the body sensor and measure a time-dependent electrical waveform, optical waveform, and pressure waveform. The disposable sensors typically include an armband that features an inflatable bladder coupled to a pressure sensor, at least 3 electrical sensors (e.g. electrodes), and an optical sensor (e.g., a light source and photodiode) attached to a wrist-worn band.
US08419646B2 Blood pressure estimation apparatus and blood pressure estimation method
To provide a non-invasive blood pressure estimation apparatus, which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and continuously estimate systolic blood pressure by continuously picking up the blood flow sound. A blood pressure estimation apparatus creates a standard pulse curve by relating a start point and end point of a rising phase of a pulse wave to diastolic blood pressure and systolic blood pressure, respectively, creates a correspondence curve between blood flow sound power and estimated blood pressure by contrasting the standard pulse curve with the blood flow sound power curve obtained from blood flow sound at a shut site, with the two curves plotted on the same time axis, derives a systolic blood pressure estimation linear function from the correspondence curve, inputs a measured maximum value of the blood flow sound power into the linear function, and thereby estimates systolic blood pressure.
US08419642B2 Device for measuring the viscoelastic properties of biological tissues and method using said device
A device configured to measure the viscoelastic properties of biological tissues using a processing of ultrasound waves reflected by these tissues when a shear wave runs across them is presented. The device includes memories for forming lines of data such that each line comprises data relative to the ultrasound waves reflected from the same shot and a calculator for determining a parameter relative to the displacement between the tissues and a transducer emitting the shots, a calculator for calculating an intrinsic displacement of the medium from a set of lines forming an acquisition, and a processor for processing the first ultrasound lines, by using the relative parameter, before or during the formation of second ultrasound lines from this same acquisition, in order to determine the intrinsic displacement of the biological tissues from these first lines.
US08419641B2 Medical image display method, medical image diagnostic apparatus, and medical image display device
Disclosed is a medical image display method for displaying a tomographic image obtained by scanning an image of a cross-section of an organ of an object and finding the volume of an inner cavity region surrounded by the inner wall surface of the inner cavity of the organ on the basis of the displayed tomographic image, comprising a step that segmentizes the inner cavity region into a first inner cavity region and a second inner cavity region, a step that calculates volume of the first inner cavity using the disk method, a step that calculates volume of the second inner cavity region using the pseudo disk method, a step that calculates the entire inner cavity volume by summing the calculated volumes of the first and the second inner cavity, and a step that displays the first and the second inner cavity volumes and/or the entire inner cavity volume.
US08419632B2 Body-insertable apparatus having light adjustment control unit and in-vivo information acquisition system
A body-insertable apparatus to be inserted into a subject includes an illumination unit that illuminates an inside of the subject; an imaging device having an effective pixel region that has a predetermined size and on which an optical image of the inside of the subject illuminated by the illumination unit is formed, and having an optical black region at which the optical image is shielded; and a light adjustment control unit that adjusts an amount of light from the illumination unit to the effective pixel region based on pixel values of the effective pixel region of an image signal and pixel values of the optical black region of the image signal.
US08419630B2 Endoscope system with front and lateral fields of view
An endoscope system including an endoscope which acquires a front field-of-view image and a lateral field-of-view image of an object of observation; a detecting section which has a function capable of detecting whether a treatment instrument is used or not in the endoscope based on a notification signal which is outputted when the treatment instrument is inserted into the endoscope; and an image processing section. The image processing section generates an observation image including the front field-of-view image and the lateral field-of-view image within the same screen, displays a magnified image of one field-of-view image out of the front field-of-view image and the lateral field-of-view image on a display, and performs adjacent part display processing of displaying only a part of the one field-of-view image which is adjacent to the other field-of-view image or image compression processing of displaying a compressed image of the other field-of-view image on the display.
US08419629B2 Encapsulated endoscope system in which endoscope moves in lumen by itself and rotation of image of region to be observed is ceased
An encapsulated endoscope system in accordance with the present invention comprises: an encapsulated endoscope that rotates to develop a thrust; a controller that moves the encapsulated endoscope in an intended direction of advancement; an imaging unit incorporated in the encapsulated endoscope; and an image processing unit that receives image data sent from the imaging unit, and produces an image, which results from rotation of the received image data, according to the rotational phase of the encapsulated endoscope.
US08419627B2 Transmitting/receiving system and medical system
A transmitting/receiving system includes a transmitting apparatus that generate modulated signals each containing a broadband signal component and a narrowband signal component, and transmits the modulated signals to the outside; and a receiving device that receives the modulated signals via at least three receiving antennas. The receiving device includes a signal processing system that processes the broadband signal component contained in the modulated signal; and a received-strength detecting system that processes the narrowband signal component contained in the modulated signal.
US08419619B2 Endoscopic form detection device and form detecting method of insertion section of endoscope
An endoscopic form detection device includes a posture detecting section configured to detect a posture of each of sensor units based on measurement data in the sensor unit, and a linear form detecting section configured to detect a detected linear form of an inserting section on an assumption that a form between the respective sensor units is a linear link whose dimension is equal to an inter-sensor dimension based on the detected posture of each of the sensor units. The endoscopic form detection device includes a curve form detecting section configured to perform curve interpolation with respect to the detected linear form detected on an assumption that a form between the respective sensor units is an arc whose arc length is equal to the inter-sensor dimension, and configured to detect a detected curve form.
US08419613B2 Tissue visualization device
Tissue visualization device having a fluid barrier is described herein where an imaging hood is temporarily sealed against a region of tissue to be treated while under direct visualization. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. The imaging hood is placed against or adjacent to the tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A field of view of the imaging element can be expanded and the blood can also be purged in part by inflating a balloon beyond the imaging hood where the balloon is integrally formed along an interior surface of the hood.
US08419612B2 Method treating erectile dysfunction via a penile implant with dilatant liquid
A method treating erectile dysfunction includes implanting a penile implant including a first bladder and a second bladder, the second bladder filled with a liquid having a rest viscosity. The method additionally includes increasing a pressure in the first bladder of the penile implant from a first pressure to a second pressure, and increasing a viscosity in the liquid from the rest viscosity to a second viscosity greater than the rest viscosity. The method further includes maintaining the first bladder of the penile implant at the second pressure and the liquid in the second bladder at the second viscosity.
US08419608B2 Apparatus for producing fields for treatment of bodily parts of living organisms for healing purposes
In the process of generating high frequency magnetic fields for treating living organisms, an apparatus for limiting undesirable interference and disturbance that may be caused by electromagnetic radiation from said fields.
US08419606B2 Compact dunnage converter
A compact dunnage conversion machine includes a converging chute with a restricted inlet, a powered feed assembly with a sealed gearbox, a plurality of interchangeable power supplies, and a restricted outlet chute. The converter can convert a sheet stock material into dunnage for use in packaging one or more objects in a container. The restricted inlet and outlet make it more difficult for foreign objects to enter the converter and disrupt the conversion process. The sealed gearbox interposed between the driving elements of the feed assembly and an electric motor facilitates maintenance and repair of the feed assembly, while also protecting the gears therein. Finally, the power supplies provide electrical power to the motor and can include an electrical storage device, such as a battery, or an alternating-current-to-direct-current converter which is connectable to a source of electricity for supplying that electricity to the motor in an acceptable form.
US08419600B1 Resistance training exercise apparatus with vacuum load system
Resistance training exercise apparatus includes a vacuum load system. Movement of a user-engaged exercise member in a first exercise direction pulls a piston in a cylinder to create vacuum in a housing chamber, which vacuum provides load resistance resisting exercise movement of the user-engaged exercise member.
US08419599B2 Underwater exercise and physical therapy device for joint release and spinal adjustment
The present invention relates to an underwater exercise and physical therapy device for joint release and spinal adjustment wherein a tube is worn on a user's upper body and weights are worn on the user's feet in a water tank having a predetermined depth wherein his feet are spaced apart from the bottom surface thereof to carry out underwater exercise and physical therapy by using the buoyant force of the tube and the gravity of the weights, thereby enabling his joints to be released, making his muscles reformed, and further adjusting and preventing his spinal diseases.
US08419597B2 Systems and methods for a hill training apparatus for a bicycle trainer
A bicycle trainer with a hill training apparatus is described. The hill training apparatus enables bicyclist to simulate uphill riding (incline), downhill riding (decline) and hill resistance or lack thereof. The hill training apparatus also provides for correct body positioning while riding uphill or downhill and with or without resistance. Riding on a trainer with correct body positioning provides for improved training.
US08419595B1 Dental appliance and method of fitting
An elastomeric dental appliance to reduce the effect of facial age lines has a U-shaped channel piece with a continuous bottom wall, walls extending from the bottom wall inner and outer edges, bite pads on the upper and lower surfaces of both legs of the channel piece, and a wing extending upwardly from the top edge of the outer wall of each channel piece leg to engage the inside of the lips in the areas of the naslobial fold lines and push them outwardly. During fitting the appliance is placed in a heated liquid to soften, the user protrudes the lower jaw by a distance of from 1-3 mm from the normal position and bites into the bite pads to make teeth impressions so that the appliance in use provides a vertical separation of about 3 mm between the opposing teeth occlusal surfaces with the jaw protruding forward.
US08419593B2 Fitness facility equipment usage control system and method
An electronic method of obtaining exercise equipment information. The method including using a first control server associated with a first fitness facility to gather first usage information from a first fitness equipment unit, sending the first usage information from the control server to an accumulated data storage unit, and using the first control server associated with the first fitness facility to gather second usage information from a second fitness equipment unit. The method further including sending the second usage information from the control server to the accumulated data storage unit, and sending the first usage information from the accumulated data storage unit information to a requester.
US08419590B2 Method for operating a hybrid drive of a motor vehicle
A method is provided for operating a hybrid drive of a motor vehicle which has a combustion engine, at least one electrical machine, and at least one electrical accumulator, the electrical machine and the electrical accumulator belonging to an electrical system of the motor vehicle. The following steps are provided for implementing the method: subdividing the operation of the electrical machine into adjacent subranges of a) transient compensation operation, b) boost and/or recuperation operation, and c) operation for maintaining the vehicle electrical system; assigning torque limits and/or power output limits of the electrical machine in at least two subranges; and, releasing and/or influencing the particular torque limits and/or power output limits of the subranges as a function of the current state of the electrical accumulator and/or of the electrical machine and/or of the vehicle electrical system.
US08419583B2 Front differential for a vehicle
A front differential for a four wheel drive vehicle, includes: a switching mechanism that switches the vehicle between rear-wheel drive and front- and rear-wheel drive by selectively interrupting or allowing the transmission of power between one of a pair of side gears and one of a pair of front wheels; and an urging mechanism that urges at least one of the pair of side gears in a drive shaft axial direction toward at least one of the front wheels.
US08419582B2 Dual-clutch group transmission and method for actuating a dual-clutch group transmission
A dual-clutch group transmission having splitter, main and range groups. The range group is a planetary transmission with a ring gear, a sun gear and planetary gears that are supported by a carrier. Inner and outer transmission input shafts are connected to a respective first and second clutch. A main transmission shaft and shifting elements for engaging gears or forming frictional connections. Power-gearshifts, involving a shift of the range group, are enabled because the inner input shaft can be directly connected, via a shift element, to the main shaft. A hollow shaft extends coaxially over the main shaft and supports a loose wheel of a forward gear of the main group. The wheel can be rotationally fixed, via a shift element, to the hollow shaft which can be connected to the main shaft and the carrier by respective shifting elements.
US08419579B2 Transmission device
A transmission device, for a motor vehicle, with at least two drive output shafts and two multi-shaft planetary gearsets in active connection with one another. A shaft of a planetary gearset is actively connected with an output shaft and is shifted, between first and second power paths, such that in the first power path, torque of an electric machine is transmitted in equal parts and with the same sign to the output shafts, and in the second power path, torque is transmitted in equal parts but with different signs. One of the two planetary gearsets is made as a four-shaft, reduced coupling transmission with two sun gears and a common planetary gear carrier with radially inner and outer planetary gears that mesh with one another, and which are engaged, on the one hand, with the sun gears and, on the other hand, with a rotationally fixed ring gear.
US08419578B2 Hydrostatic regenerative braking transmission for motor vehicles
A transmission for a vehicle including a hydrostatic regenerative braking system includes a first rotatable shaft having a first end adapted to be driven by a first prime mover and a second end adapted to be coupled to a vehicle driveline. A second shaft selectively drives the first shaft and is adapted to drive a hydraulic pump of a second prime mover. A planetary gearset includes a first member restricted from rotation, a second member and a third member. A transfer mechanism includes a first sprocket fixed for rotation with the second member, a second sprocket fixed for rotation with the input shaft and a flexible member interconnecting the first and second sprockets. A clutch transfers torque between the third member and the first shaft.
US08419577B2 Propulsion system for all-wheel drive motor vehicles
The invention relates to a propulsion system for all-wheel drive motor vehicles, having a device for propulsion distribution to the front and the rear differential which transmit the drive output to the wheels assigned at the time, and with a device for coupled, variable distribution of the propulsion forces in the transverse and longitudinal directions of the vehicle depending on the operating situation of the vehicle for influencing the driving behavior, especially for improving the driving agility and driving stability. In the process the rear differential (18) is combined with an overriding drive (22), by means of which the drive torques can be shifted to the rear wheels (20) in alternation in the transverse direction of the vehicle, the rpm ratio or rpm error being dictated by means of the overriding drive (22) at the design point so that at a given curve radius which is assigned to the design point and which does not correspond to the narrowest curve, a reversal of the direction of the rotational speed difference takes place and thus the torque is not shifted to the wheel on the outside of the curve. By means of the propulsion distribution device (24, 26; 44, 46; 52) the drive torques can be shifted in alternation between the front differential (14) and rear differential (18) in the longitudinal direction of the vehicle.
US08419574B2 Isolator
An isolator comprising a shaft (10), a pulley (20) journalled to the shaft on a first bushing (40) and a second bushing (50), the shaft comprising a shaft stop (12) disposed on a shaft radially outer surface (14), the pulley and the shaft rotationally moveable relative to each other, the pulley comprising an inner hub (23), the inner hub having a pulley stop (24) disposed to cooperatively engage the shaft stop, a torsion spring (30) engaged with the shaft and the pulley, the torsion spring exerting a contractive force parallel to an axis of rotation (A-A) in order to retain the pulley on the shaft, a cover member (60) fixed to the shaft, the pulley urged into engagement with the cover member by the torsion spring axial contractive force, and a rubber member (80) disposed on the shaft stop for engaging the pulley stop.
US08419572B1 Training tool and method for ball handling
Tools, devices, apparatus, systems and methods to enhance ball handling skills and reduce and eliminate fumbling of balls, from football players, basketball players and the like. The training tool can be used to improve ball security for football players of every level to reduce or even eliminate fumbling. The tool can simulate the forces imparted on a football that can cause a fumble during the game. Used during various drills in practice, the invention will improve the player's ability to maintain possession of the football during actual game play. The invention assembly can include a ball (such as a football, basketball or rugby ball), a rope, and a reciprocating handle weight subassembly. The tools can use a slightly vertical handheld sliding reciprocating weight with or without a spring(s), or motor, in order to cause shockwaves that pass to a player carrying a ball to simulate a fumbling condition during a game, where other players are trying to slap or grab or push or jar loose a ball from the grasp of the ball carrier. The reciprocating weight can be quickly pumped and/or jerked by the trainer/coach during drills to surprise and replicate a fumbling condition.
US08419568B2 Muscle-back, with insert, iron type golf club head
A muscle-back iron golf club head includes a blade-like upper mass, a muscle-like lower mass, a planar front surface, a top surface, a sole surface, a heel surface, a toe surface, and a rear surface having a first contour. A recess is in the rear surface, the recess having a first portion in the blade-like upper mass and a second portion in the muscle-like lower mass. An insert may be provided in the recess, and such insert may substantially fill the recess and may include a back surface having a second contour which is different from the first contour of the club head rear surface.
US08419565B2 Grip structure with weight and golf club
There is provided a golf club where a separation of a weight for swingweight adjustment can be certainly prevented and the weight can be easily detached/attached and replaced; concurrently, the center of gravity is slanted toward the shaft side, and the center of gravity position can be stabilized. The golf club 10 has a grip part 16 and a weight part 18. A threaded shaft 26 is established at the grip part 16 side, and a female screw part 22 is established in the weight part 18. In the gold club 10, the grip part 16 and the weight part 18 can be integrated in the state where a spring washer 30 is interposed, by screwing a threaded shaft 26 with a female screw part 22 under a condition where the spring washer 30 is mounted to the threaded shaft 26.
US08419563B2 Releasable connections for golf club heads and shafts
Golf club heads are releasably engaged with shafts so that the club heads and shafts can be readily interchanged and/or so that the shaft position with respect to the club head can be readily changed. Golf clubs are provided that have spherical releasable connections between the golf club head and the golf club shaft along with head/shaft position adjusting features to allow interchange of shafts and heads and to allow modification of the head/shaft positioning properties. Assemblies for connecting the club head and shaft may include: a shaft adapter, a shaft retainer, and a hosel insert located within an interior chamber of the club head. The club head and shaft may be changed by releasing the securing system and exchanging the original parts with different parts.
US08419562B2 Apparatus for deceleration training for golf
An apparatus comprises a structure comprising a top, a bottom, a sidewall, a central hole extending from the top to the bottom, a void in a section of the sidewall, and a curved cavity disposed in the top. The central hole is configured to accept a shaft of a golf club. The void is configured to enable a length of the shaft to pass through the sidewall into the central hole. A compressible material is joined to a wall of the central hole to contact the shaft. A clasp is joined to the structure. The clasp is operable to rotate about the sidewall to close the void and retain the shaft within the central hole. A spring mechanism is disposed in the curved cavity and is joined to the structure and the clasp. The spring mechanism is configured to be operable to urge the clasp to close the void.
US08419560B2 System and method for adaptive delivery of game balls based on player-specific performance data analysis
A game ball delivery apparatus that adjusts the delivery of game balls to the actual practice needs of the player returning the delivered game balls, based on a computer analysis of player performance data, including but not limited to data collected from inertial and physiological sensors. The parameters of delivery, such as trajectory, speed, and interval of successive balls, are modified in real-time, as the player is training. One or more highly miniaturized sensors for collecting performance data are worn by the player without affecting the player's motions. A computer capable of analyzing said sensor data, selects delivery parameters for subsequently delivered balls, and transmits said delivery parameters to the ball ejector controller. Further, the system may optionally include a means for generating a feedback signal to the player to indicate deviations of the measured motion of the player from reference performances of the motion.
US08419553B2 Torque fluctuation absorber
A torque fluctuation absorber includes a first damper portion absorbing torque fluctuations caused by a torsion between a first rotary member and a second rotary member, a second damper portion absorbing torque fluctuations caused by a torsion between the second rotary member and a third rotary member, and a stopper portion. The first rotary member includes a first projecting portion projecting radially inwardly and being contactable with the stopper portion by the torsion between the first rotary member and the second rotary member. The third rotary member includes a second projecting portion projecting radially outwardly and being contactable with the stopper portion by the torsion between the third rotary member and the second rotary member. The second projecting portion makes contact with the stopper portion at a radially inner side relative to a portion where the first projecting portion makes contact with the stopper portion.
US08419550B2 Cashbox security mechanism and gaming machines with a cashbox security mechanism
Cashbox security mechanisms, gaming machines with a cashbox security mechanism, and methods for securing and removing a portable cashbox from a gaming machine are presented herein. The cashbox security mechanism stores and secures a cashbox, which stows currency received, for example, from a currency processing device. The cashbox security mechanism includes an outer housing, such as a gaming machine cabinet or a substructure mounted inside a cabinet. An inner chassis mates with and retains the cashbox. The inner chassis and a security door are pivotably mounted with respect to the outer housing. The security door and inner chassis are positionable to cooperatively secure the cashbox within the cashbox security mechanism. Likewise, the security door and inner chassis are respositionable to cooperatively define an access chute through which the cashbox is removable from the cashbox security mechanism.
US08419549B2 Gaming system having multiple gaming devices that share a multi-outcome display
A linked gaming device system in which a plurality of gaming devices are linked by a common bonus event is provided. In one embodiment, the linked gaming device system includes a shared symbol generation display positioned adjacent to each of a plurality of associated gaming devices and having a plurality of sections and values displayed at each section. Upon a triggering of the bonus event, any player eligible to participate in the bonus may achieve an outcome generated from the bonus event including the shared display. When the shared display is activated, it simultaneously generates an individual outcome associated with each gaming device. The outcomes are spatially related to one another so that a random generation of an outcome associated with one gaming device automatically generates random outcomes associated with each gaming device. However, each gaming device receives the outcome only if it has participated in the random generation.
US08419547B1 Iterative XOR-matrix forward error correction for gaming
A wagering game system and its operations are described herein. In some embodiments, the operations can include receiving a packet of gaming data. The packet includes data units and exclusive-OR check bytes. The data units and exclusive-OR check bytes are organized in the packet to correspond to vectors (e.g., columns and rows) of a matrix. Each of the exclusive-OR check bytes represent a result of a logical exclusive disjunction operation on a sequence of the data units contained in each of the vectors. The operations can further include detecting that some of the data units have data corruption and selecting one of the exclusive-OR check bytes that corresponds to one of the vectors. The one of the vectors includes only one corrupted data unit. The operations can further include recovering the one corrupted data unit using the one of the exclusive-OR check bytes that corresponds to the one of the vectors. In some embodiments, the operations further include repeatedly selecting groups of the vectors that have only one corrupted data unit and recovering the one corrupted data units from the groups of the vectors.
US08419544B2 Systems and methods for interactive wagering using multiple types of user interfaces
The present invention is systems and methods for interactive wagering using multiple types of user interfaces. Preferred embodiments of these systems and methods incorporate a wagering data hub which controls the flow of data relating to wagers, wagering events, and wagering account and facilitates the use of a variety of user interfaces such as graphical user interfaces and interactive voice response interfaces. For example, a user of the present invention may use a television set-top box, a computer, a telephone, and/or any other suitable device. To communicate with the wagering data hub, television set-top boxes preferably use a two-way cable system, computers preferably use a computer network, and telephones preferably use a telephone network, although each may use any suitable mechanism or combination of mechanisms to communicate with wagering data hub.
US08419543B2 Methods and apparatus for providing communications services at a gaming machine
In a first aspect, a method is provided that includes the steps of (1) providing an auxiliary unit adapted to allow a gaming machine to be retrofitted to provide communications services; and (2) retrofitting a non-communications-enabled gaming machine with the auxiliary unit so that the non-communications enabled gaming machine is adapted to provide communications services based on game play at the non-communications-enabled gaming machine. Numerous other aspects are provided.
US08419542B2 Wide area bonusing systems
The present invention provides a novel bonusing system implemented on gaming machines and associated network devices on a network. According to some implementations, a central system qualifies or eliminates sites and/or types of gaming devices for participation based on criteria such as contribution level, games available, date range, location, device manufacturer, denominations available, etc. In some implementations, the qualification or elimination process is performed at a site (e.g., by a site controller) according to criteria obtained from the central system. The methods of the present invention may be de-coupled from player tracking methods.
US08419539B2 Game apparatus and recording medium recording game program for displaying a motion matching a player's intention when moving an input device
Operation information which is output, depending on a motion of an input device is successively obtained, and based on the operation information, a direction and movement velocity of the input device is determined. Next, it is determined whether or not the movement velocity is larger than or equal to a first threshold value. When the movement velocity is larger than or equal to the first threshold value, a path along which an object is moved in a virtual world is determined based on predetermined information about the movement path. When the movement velocity is smaller than the first threshold value, a path in which the object is moved in the virtual world is determined based on the determined movement velocity. Based on the determined movement path, it is displayed how the object is moved through positions in the virtual world.
US08419528B2 Gaming system and method including anonymous player tracking
A gaming system and method are disclosed that include anonymous and identified player tracking, wherein gaming data is collected over one, two, or more gaming sessions, the data is analyzed to determine whether a selected criterion or selected criteria have been met, and if so, then initiating a response, such as triggering a flag or transmitting a notification to an operator.
US08419524B2 Gaming device having a plurality of wildcard symbol patterns
A gaming device which includes a variety of methods to allow the player to select patterns of wildcard symbols, from a plurality of wildcard symbol patterns, and use those patterns during subsequent games. One embodiment allows the player to select a pattern of wildcard symbols and use the selected pattern during a free spin bonus game.
US08419521B2 Method and apparatus for card handling device calibration
A device for automatically calibrating for card size and thickness during card handling is disclosed. The device includes a card receiving area, a card stacking area and a card moving system for moving cards from the card receiving area to the card stacking area. An elevator located in the card stacking area has a movable platform for moving a stack of cards. At least one sensor senses at least one of position of the platform, height of the platform, position of a card in the elevator, height of a card or cards in the elevator, pressure applied to a card in the elevator, presence of the platform at a predetermined height, presence of the platform at a predetermined position, presence of card(s) on the platform, and absence of card(s) on the platform. A method for calibrating a card handling device during shuffling is also disclosed.
US08419520B2 Tournament game, gaming machine, gaming system and method with a player-interactive bonus feature
A tournament game, gaming machine, gaming system and method are disclosed wherein a player-interactive bonus feature is triggered and displayed simultaneously with a tournament game presentation and a bonus award is paid responsive to a player selecting a displayed bonus target, such as a balloon. The bonus award is paid in addition to any award payable based on the tournament game outcome.
US08419518B2 Gaming device having multiplier poker game
A video poker gaming device, a method of operating a gaming device and a method of playing a poker game including a plurality of cards displayed to a player where the cards are drawn from a deck of fifty-two cards including at least one modifier card. The gaming device deals a first draw of the cards to form a player's hand. Any multiplier cards in the player's hand are replaced by a non-multiplier card. The gaming device enables the player to hold any of the cards in the hand and then determines if any winning card combinations are indicated by the non-multiplier cards in the hand. An award associated with any indicated winning card combinations is provided to the player. The award is multiplied by the multipliers associated with any multiplier cards in the player's hand.
US08419510B2 Poultry deboning knife
A safety use deboning knife includes a blade having a distally disposed carcass flesh penetration tip disposed immediately adjacent the blade curved cutting edge and spacedly disposed from the blade non-cutting upper edge by a planar distal edge, which distal edge subtends an acute angle of less than about 45° and preferably in less than about 25° with entire cutting portion disposed below the blade center line.
US08419509B2 Swivel device and grinding machine incorporating the same
In a swivel device, a swivel head provided with a plurality of tool spindles thereon is mounted on a support base to be turnable about a swivel shaft being upright on the support base. An annular space portion is formed between the support base and the swivel head in coaxial relation with the swivel shaft. The tool spindles each mounting a grinding wheel are arranged on the swivel head to extends in a horizontal plane which crosses the annular space portion at about a mid position in the vertical direction of the annular space portion. A direct drive motor is built in the annular space portion so that a driving center of the direct drive motor is at almost the same height as the horizontal plane including the axes of the grinding wheels. Thus, the swivel device can lower the positions of the rotational axes of the grinding wheels and is rigid against inclination caused by grinding resistance acting on the grinding wheels.
US08419506B2 Dual capability ultra high pressure fire attack system
A dual capability ultra high pressure (UHP) fire attack system includes a fluid jet assembly and an UHP attack line system. The fluid jet assembly and the UHP attack line system are coupled to a high pressure fluid source. The fluid is discharged from both the fluid jet assembly and the UHP attack line system as a mist have a droplet diameter of approximately 150 microns. When infused with an abrasive material, the fluid jet assembly may be used to cut through structural surfaces, so that a fire may be “knocked down” before the fuel source is attacked.
US08419501B2 Apparatus for continuous weight monitoring of beehives
An apparatus and method for continuously monitoring the weight of an object. The apparatus does not obstruct a central portion of the bottom of the object being monitored, and is especially well-suited for monitoring the weight of a beehive. In the illustrative embodiment, a ring-shaped fluid-filled bladder is sandwiched between a ring-shaped top surface and a ring-shaped base, and a pressure hose connects the bladder to a pressure gauge. Beehive weight data can be obtained in a continuous fashion, without requiring any moving of the beehive or of the apparatus, and without any other type of disruption. Moreover, the apparatus provides a stable platform that keeps the beehive immobile during monitoring, which is beneficial for the health of the colony. Advantageously, the apparatus can be constructed from inexpensive, off-the-shelf components and materials, and is capable of obtaining accurate measurements over a wide range of temperatures and environmental conditions.
US08419498B2 Vehicle toy
A vehicle toy makes an imagination of an appearance of a second mode which is transformable from an appearance of a first mode difficult. A vehicle toy transformable between a first mode and a second mode includes a base member having a front surface forming part of the first mode and a back surface forming part of the second mode, at least two or more rotating members each rotatably coupled to the base member and having different features on the front surfaces and the back surfaces thereof so that the front surfaces form the first mode and the back surfaces form the second mode, and have connecting portions disposed at respective ends of at least two of the rotating members connecting to each other and retain the vehicle toy in either the first mode or in the second mode.
US08419493B2 Method and apparatus for manufacturing light source
An apparatus for manufacturing a light source and a method therefor are provided that enables a high efficient light source to be manufactured even when an optical element whose characteristic significantly varies is used. After maintaining temperatures of a laser device and a wavelength conversion element at a temperature where an output of light emitted from each of the device and the element is equal to or greater than a predetermined rate of the maximum output, the laser device and the wavelength conversion element whose temperatures have been maintained are joined together so that the output of the light emitted from the wavelength conversion element is equal to or greater than a predetermined value.
US08419488B2 Steering apparatus for outboard motor
Support arms are disposed on a tilting shaft on a bracket of an outboard motor. An electric actuator is mounted between the support arms. The electric actuator includes a cover member, first and second electric motors disposed individually on the opposite ends of the cover member, a feed screw configured to be rotated by the electric motors, a nut member configured to move along an axis as the feed screw rotates, a drive arm configured to move integrally with the nut member and transversely relative to the boat body, and protective boots. The drive arm is connected to a steering arm through an engaging member. If the drive arm moves in the direction of the axis along the cover member, the steering angle of the steering arm changes depending on the degree of movement of the drive arm.
US08419480B2 Board-mounted electrical connector
A board-mounted electrical connector has an insulating housing, a first contact module, a second contact module, a spacer and a shell encasing the housing, the first and the second module and the spacer. The housing forms a main body defining a receiving space and a mating tongue extending forwardly from the main body. Each of the first and the second contact module has a first/second insert and a plurality of first/second contacts insert-molded in the first/second insert. The spacer is assembled with the first and the second contact module, and defines a plurality of through holes.
US08419473B1 Electrical connector
An electrical connector includes an insulating housing defining a plurality of terminal grooves each extending along a front-to-rear direction. A plurality of terminals includes a plurality of flat terminals made by stamping and bending metal strips and a plurality of spring terminals made by die-cutting upright metal boards of long rectangular shape. Each spring terminal is inserted forward and uprightly positioned in the corresponding terminal groove of the insulating housing without being pressed and bent. The flat terminals are molded in the insulating housing with front ends thereof acted as contacting ends and exposed outside. A lid is mounted to a back of the insulating housing for positioning a rear of the spring terminal. A latch is inserted forward in the insulating housing. A shielding shell is mounted to the insulating housing and electrically connects with the latch.
US08419470B2 Coaxial connector having detachable locking sleeve
A connector is provided for terminating coaxial cable. The connector includes a connector body having a cable receiving end and an opposed connection end. A locking sleeve is provided in detachable, re-attachable snap engagement with the insertion end of the connector body for securing the cable in the connector body. The cable may be terminated to the connector by inserting the cable into the locking sleeve or the locking sleeve may be detachably removed from the connector body and the cable inserted directly into the cable body with the locking sleeve detached subsequently.
US08419469B2 Audio jack connector device and method of use thereof
A phone plug style audio jack connector device having an audio jack and a connector, the audio jack having a socket adapted to receive the tip end of the phone style audio plug. The device is movable between an unassembled position and an assembled position. When the device is in the unassembled position, a prepared coaxial cable end can be inserted into the rear end of the device. When a user moves the device into its assembled position, a fastener is driven to clamp around the cable in the radially inwards direction, thereby forming a connector/cable assembly. The electrical connections, or conduction paths, that run through the connector device are preferably coaxial, and connectors according to the present invention also provide good coaxial shielding within the connector device itself.
US08419468B2 Coaxial connectors having backwards compatability with F-style female connector ports and related female connector ports, adapters and methods
Coaxial connectors are provided that include a connector body having a front end and a rear end, an inner contact post that is at least partly within the connector body, a first internally-threaded nut that is positioned at the front end of the connector body and that is connected to at least one of the connector body and the inner contact post and a second structure that is attached to the first internally-threaded nut. In some embodiments, the second structure may comprise an internally-threaded nut. In other embodiments, the second structure may comprise a locking member. Corresponding female connector ports are also provided.
US08419464B2 Coaxial connector with integrated molded substrate and method of use thereof
A substrate structure is provided, the substrate structure comprising: a molded substrate located within a connector body of a coaxial cable connector and an electrical structure mechanically connected to the molded substrate. The electrical structure is located in a position that is external to a signal path of a radio frequency (RF) signal flowing through the coaxial cable connector. The electrical structure may form a sensing circuit configured to sense physical parameters such as a condition of the RF electrical signal flowing through the connector or a presence of moisture in the connector.
US08419462B2 Lever type connector
A lever in a lever type connector which is attached to a first housing, is rotated to fit the first housing to a second housing, and has a pair of side walls and an operation potion connecting the side walls. Locking arms are provided on the side walls so as to project toward an opening of the first housing into which the second housing is fitted. Temporary locking releasing portions are provided in the first housing. The locking arms are deformed into a state that a part of each of the locking arms is disposed on each of the temporary locking releasing portions, so that the lever is elastically deformed, when the lever is rotated. Each of the temporary locking releasing portions has an inclined face on which each of the locking arms is moved in a direction which the lever is elastically restored after the locking arms are deformed by the temporary locking releasing portions.
US08419458B2 Tubular connection system facilitating nonrotating signal conductor connection and method
A tubular arrangement including a tubular form having an interconnection configuration on each end with one or more signal conductors disposed within the tubular form. One or more axially operative connector bodies disposed at each end of the tubular form. A coupling at one end of the tubular form capable of bridging the tubular form to another tubular and a method for building a string is included.
US08419455B2 Light string system
A lamp system used in a light string system comprises a light assembly and a socket assembly. The light assembly comprises a light source, a base in communication with the light source, and a bypass activating system. The socket assembly comprises a socket adapted to receive the light assembly and a bypass mechanism having a first position and a second position. The bypass mechanism is in the first position when the light assembly is not seated in the socket assembly. When the bypass mechanism in the first position, current flows across the bypass mechanism. When the light assembly is inserted into the socket assembly, the bypass activating system of the light assembly moves the bypass mechanism into the second position, and current flows through the light source instead of the bypass mechanism.
US08419449B1 Split electrical grounding bushing with continuous insulation
A split electrical grounding bushing having adjacent bushing portions with insulating bushing portions having guard tabs covering a gap formed between the insulating bushing portions creating a continuous insulating ring. The bushing portions are connected by a hinge permitting the bushing to be placed over electrical conductors or wires after being installed. Gaps in the insulating bushing portion are covered by attached guard tabs improving the safety of a split electrical bushing. The split electrical bushing is placed on a distal end of an electrical conduit. The split bushing may be an electrical grounding bushing providing an electrical ground connection.
US08419438B2 Interactive education system for teaching patient care
A newborn simulator for teaching patient care is provided. The newborn simulator includes a body comprising one or more simulated body portions sized to simulate a newborn baby and a head portion movably connected to a portion of the body. A simulated heart is positioned at least partially within the body along with a pair of simulated lungs. The simulator is operable without physical connection to an external device to provide a simulated heart beat and respiratory pattern.
US08419437B2 Device for the determination of parameters particularly for therapeutic compression means on limbs
A device for the determination of parameters, particularly for therapeutic compression measures on limbs (10), comprises an anatomically-modelled limb (10), to which the compression measures may be applied, with sensors (42), provided on the limb (10), for recording said parameter. The surface (44) of the limb (10) is at least partially elastically-deformable in at least one direction and at least one simulation device for a muscle (22, 24) is provided in the limb (10), which may be controlled to give a merely partial deformation of the surface (44) of the limb (10).
US08419436B2 Boxing punching combination training/workout system
My boxing punching combination system is the idea of identifying specific numbers to represent specific punches and having them placed at the proper location for those punches. By placing these numbers appropriately on any given apparatus, any user can easily execute boxing punching combinations regardless of the user's level of experience in boxing.
US08419435B2 Forcible entry training door system
Apparatus for training the art of forcible door entry for emergency personnel such as firefighters and, in particular, a reusable forcible entry door training apparatus that allows individuals to simulate forcible entry of outward opening metal doors mounted in metal frames.
US08419428B2 Illuminated dental retractor
A dental apparatus for retracting the cheeks and lips of a patient and illuminating the oral cavity of a patient is provided. The dental apparatus includes LEDs mounted on the cheek retractors. The apparatus allows a dentist to illuminate the interior of the oral cavity without needing additional equipment that hinders access to the oral cavity.
US08419427B2 Device for infiltration of approximal enamel lesions of teeth
The device for infiltration of approximal tooth surfaces, with a flexible planar element and with a holder into which the planar element is clamped, is characterized in that the planar element is a liquid-impermeable plastic film which has a surface area for taking up a liquid to be used for treatment, and in that the holder is a bow-shaped element with a web and two lateral arms which extend from the latter and are arranged in an arc-shape or U-shape, to which the plastic film is connected in a liquid-impermeable manner.
US08419423B2 Hot air stove
The inventive air heater comprises a housing (1) with a lining (2), a nozzle (3), a dome (5) with a prechamber (6), which is coaxially positioned in the top part thereof and is provided with a housing (7) and a lining (8) provided with an independent support (9) on the housing (7). Gas (11) and air (12) channels are made in the side vertical wall of the prechamber (10) lining and are connected to internal manifolds (14,15) and to gas (16) and air (17) supplying sleeve fittings. The channels of the lower manifold (15) are arranged in the top part thereof and are upwardly oriented at and angle of 15-30° with respect to a horizontal plane. The channels of the top manifold (14) are arranged in the lower part thereof and are downwardly oriented at an angle of 15-30° to a horizontal plane. The projections of all the channels on a horizontal plane form an angle of 15-45° to the projections of the prechamber radii, passing over the centers of the outlet sections of the channels (11, 12), on a horizontal plane. The use of the invention makes it possible to reduce operation costs and to improve gas burning.
US08419421B2 Injection flame burner and furnace equipped with same burner and method for generating flame
An injection flame burner in which temperature of the generated flame itself can be sustained around the flame. A plurality of double structure injection nozzles each consisting of an outer tube and an inner tube provided coaxially with the outer tube, are arranged such that hydrogen gas is ejected from one of the outer tubes and the inner tubes and oxygen gas is ejected from the other tubes, and the injection port of each injection nozzle is located on the injection surface. Each injection nozzle includes at least one main injection nozzle having an inner tube formed to spread toward the injection surface side, and another sub-injection nozzle arranged around the main injection nozzle, wherein gas is injected from the inner tube of the main injection nozzle under a higher pressure state as compared with gas injected from the sub-injection nozzle.
US08419420B2 Burner
A burner includes a first fuel feed and a first oxidant feed surrounding the first fuel feed in the shape of a ring. The burner includes a second fuel feed arranged about the first oxidant feed in the shape of a ring, and a second oxidant feed arranged about the second fuel feed in the shape of a ring. In addition, a plurality of oxygen lances are provided, which have a smaller radial distance from the burner centre than the second fuel feed.
US08419404B2 Modular molding assembly for electronic devices
A modular molding assembly comprises an input module for loading electronic devices for molding, a press station including one or more molding presses for molding the electronic devices, an output module for offloading molded electronic devices after they have been molded and a carrier that is movable at least between the input module and the press station and/or the press station and the output module. The carrier has an adaptor located thereon for detachably mounting a first attachment or a second attachment which is operative to perform a function of transporting the electronic devices and/or introducing a molding compound to the press station for conducting molding. The first and second attachments each has a corresponding mounting device for detachably mounting the first or second attachment onto the adapter and the first attachment has a different function from the second attachment.
US08419402B2 Foam stiffened hollow composite stringer
A method and apparatus for a composite stringer. A method is used for manufacturing a hollow composite stringer. Foam is formed with a mandrel installed into the foam. A composite material and the foam is laid up onto a tool in a form of a stringer. The composite material and the foam in the form of the stringer is cured to form a cured stringer. The mandrel from the foam is removed to form the hollow composite stringer.
US08419394B2 Hermetic compressor including a backflow preventing portion and refrigeration cycle device having the same
To a hermetic compressor and a refrigeration cycle device having the same, an oil separator for separating oil from a refrigerant discharged from a compression unit is added. Separated oil is recollected into an oil pump driven by a driving motor. Because refrigerant separated from the oil is prevented from being re-introduced into the compressor, a cooling capability of the refrigeration cycle device may be enhanced. Because the oil pump is driven by the driving force of the driving motor, the compressor may have a simplified configuration, and the fabrication costs may be reduced. The oil used for a crankshaft lubrication process is returned to the oil pump by forming an oil pocket between bearing surfaces of a crankshaft and the oil pump, oil may be prevented from back-flowing to the oil separator from the crankshaft. This may allow oil to be smoothly recollected into the oil pump.
US08419392B2 Variable displacement vane pump
A variable displacement vane pump having various construction arrangements, including a low pressure supply passage constantly connecting an inlet passage and an other of a first fluid pressure chamber and second fluid pressure chamber; a low pressure introduction port formed in the other of the pump body and the rear body, and opened in an other of the first fluid pressure chamber and the second fluid pressure chamber; and a low pressure introduction passage formed in the other of the pump body and the rear body, the low pressure introduction passage connecting the low pressure introduction port and the inlet ports.
US08419390B2 Electrical submersible pump system connection adapter
An electrical submersible pumping assembly having a seal section and a motor section, and seals that prevent leakage from the seal section and the motor section during assembly. The seals cooperate with a coupling assembly for coupling together shafts from both the seal section and motor section. The coupling assembly outer diameter enlarges at a shoulder that circumscribes its outer surface. In one example, the seal that prevents leakage from the seal assembly provides a sealing interface around the larger diameter portion of the coupling assembly, that is removable by sliding the coupling so its smaller diameter portion is adjacent the seal assembly. The motor section is sealed by another sealing assembly that includes a body that circumscribes the motor shaft to define an annulus, a sealing disk selectively fills the annulus. The sealing disk can also be slid away from within the body while coupling the shafts with the coupling assembly.
US08419387B1 Bag seal mounting plate with breather tube
A submersible pumping system includes a pump assembly, a motor and a seal section positioned between the pump assembly and the motor. The seal section includes a clean fluid circulation system, a contaminated fluid circulation system and at least one bag seal assembly. The bag seal assembly includes an upper mounting block, a lower mounting block and a bag seal extending over the upper mounting block and lower mounting block and providing a path for the clean fluid circulation system. The bag seal assembly further includes a mounting plate connected to the upper mounting block that limits the axial travel of the bag seal on the upper mounting block. The bag seal assembly optionally includes a breather tube connected to the mounting plate and extending along the exterior of the bag seal.
US08419385B2 Heat-dissipating fan
A heat-dissipating fan includes a shaft seat. A coil base is coupled to the shaft seat. The coil base includes a base portion and a coil unit coupled to the base portion. The base portion includes a connection port electrically connected to the coil unit. The connection port is connected to a drive circuit. An impeller includes a hub and a permanent magnet. A shaft is coupled to the hub and rotatably coupled to the shaft seat about an axis. The permanent magnet is coupled to the hub and aligned with the coil unit. Since the coil base does not include electronic elements of the drive circuit, the axial height of the heat-dissipating fan is reduced, and the structure of the heat-dissipating fan is simplified.
US08419381B2 Tandem piston pump
In a tandem piston pump (1) from which pump discharge pressure from four systems is extracted, a tilt axis direction of a front swash plate (14) and a tilt axis direction of a rear swash plate (54) are different to each other, respective discharge ports (23, 24) of a rear pump (50) are opened at a phase difference relative to respective discharge ports (21, 22) of a front pump (10), and respective pump ports (41, 42) of the front pump (10) and respective pump ports (43, 44) of the rear pump (50) are opened in different side faces (71, 72) of a port block (70).
US08419377B2 Pumping device having a pressure adjustable function
A pumping device includes a barrel, a top cover mounted on an open top of the barrel, a cylinder mounted in the barrel and connected to the top cover, a piston movably mounted in the cylinder, a plurality of check valves mounted on the piston, an operation unit mounted on the top cover and connected with the piston, a connecting unit mounted in the barrel and connected between the barrel and the cylinder, and a pressure adjusting unit connected between the barrel and the top cover. Thus, when the air pressure in the receiving chamber of the barrel reaches a predetermined value, the pressure adjusting unit provides a pressure release function to partially release the air pressure in the receiving chamber of the barrel so as to ensure a safe operation of the pumping device.
US08419376B2 Pumping device that is operated easily and safely
A pumping device includes a barrel, a top cover mounted on the top of the barrel, a first switching valve mounted on the top cover, a base mounted on the bottom of the barrel, a second switching valve mounted on the base, a cylinder connected between the top cover and the base, a piston movably mounted in the cylinder, a plurality of check valves mounted on the piston, an operation unit connected with the piston, and a conduit connected between the barrel and the base. Thus, a user has to pull or push the first switching valve and the second switching valve simultaneously to extract or suck the fluid in the barrel so as to deflate or inflate the barrel so that the pumping device has a security process and is operated in a safer manner.
US08419367B2 Vertical-axis turbine for capturing the force of moving gases or liquids and a method for its use
A vertical-axis turbine is provided, which comprises two or more arc-shaped blades which can pivot so as to decrease drag and maximize the force collected by each blade from moving gas or liquid. These arc-shaped blades can also be capable of directing moving gas or liquid from one blade to another. Additionally, these blades can comprise thin strips along their outer edge, which can increase their strength and rigidity as well as increase the amount of force captured by each blade from the moving gas or liquid.
US08419366B2 Cooling arrangement for utilization with a turbine blade in a gas turbine engine
Cooling arrangements for blades, and in particular turbine blades utilizing gas turbine engines include impingement apertures with impingement jets, which improve cooling efficiency. By providing a leading passage, which is divided at least into a lower section and an upper section, the lower section can have a wall, which is solid for structural integrity while an upper section has impingement apertures for greater cooling efficiency.
US08419365B2 Member having internal cooling passage
Provided is a member having an internal cooling passage 7c formed therein and having opposed partition walls 6b, 6c between which a medium flows to cool a parent material, including a first heat transfer rib 25a which extends from almost the center between the opposed partition walls 6b, 6c to one partition wall 6c and slants in a downstream direction of the medium, and a second heat transfer rib 25b which extends from almost the center between the opposed partition walls 6b, 6c to the other partition wall 6b and slants in the downstream direction of the medium, wherein a slit 70a or 70b which passes through between an upstream side of the cooling passage 7c and a downstream side thereof is formed in the first heat transfer rib 70a or the second heat transfer rib 70b.
US08419363B2 Variable trailing edge section geometry for wind turbine blade
A deformable trailing edge section (3) of a wind turbine blade (1), at least part of said section (3) being formed in a deformable material. The blade section (3) comprises one or more cavities (5) being in connection with or connectable to a fluid source in a way that allows fluid to stream from the fluid source to the cavity or cavities (5), so that the shape of the deformable trailing edge section (3) and thereby the camber of the blade cross-section (3) is changeable by the pressure of fluid in the cavity or cavities (5) with insignificant changes of the thickness and chord wise length of the deformable trailing edge section. Furthermore a wind turbine blade (1) is described, having at least one of such trailing edge section (s) (3) and to a system (11) for mounting a blade section (3) on a main blade (2) of a wind turbine. In addition a method of manufacturing a deformable trailing edge section (3) of a wind turbine blade (1) is disclosed.
US08419356B2 Turbine seal assembly
A seal assembly that limits gas leakage from a hot gas path to one or more disc cavities in a turbine engine. The seal assembly includes a seal apparatus that limits gas leakage from the hot gas path to a respective one of the disc cavities. The seal apparatus comprises a plurality of blade members rotatable with a blade structure. The blade members are associated with the blade structure and extend toward adjacent stationary components. Each blade member includes a leading edge and a trailing edge, the leading edge of each blade member being located circumferentially in front of the blade member's corresponding trailing edge in a direction of rotation of the turbine rotor. The blade members are arranged such that a space having a component in a circumferential direction is defined between adjacent circumferentially spaced blade members.
US08419355B2 Fluid flow machine featuring an annulus duct wall recess
A fluid flow machine has a flow path provided by a casing (1) and a rotating shaft (2), in which rows of rotor blades (3) and stator blades (4) are arranged, and includes at least one annular groove-type recess (5) being disposed in a blade (3, 4) tip area in an annulus duct wall of the casing (1) and/or the shaft (2). An upstream end point (E) of the recess (5) in a flow direction is set at a distance (e)>0 forward of a forward blade tip point (A), and a downstream end point (F) of the recess (5) is set at a distance (f) rearward of point (A), where: 0.5 L>(f)>0, and L is a distance between point (A) and a rearward blade tip point (B).
US08419354B2 Steam turbine
A steam turbine includes two or more rotating blades and a diaphragm outer ring. Each of the rotating blades includes a tip cover, moisture-trapping grooves, a droplet ejection hole, and a drain guide groove. The tip cover is provided to a tip of each of the rotating blades and is connected in contact with another tip cover adjacent to the tip cover. The moisture-trapping grooves are formed in a longitudinal direction of each of the rotating blades. The droplet ejection hole is to connect an outside of the tip cover on a side of the diaphragm outer ring with an inside of the tip cover. The drain guide groove is to connect ends of the moisture-trapping grooves on the side of the tip cover with the droplet ejection hole. The diaphragm outer ring includes a drain pocket which faces the droplet ejection hole.
US08419339B2 Connecting member of construction machine
A connecting member of a construction machine has an intermediate support member disposed between first and second support plates. The intermediate support member has a bottom plate formed with a draw-out hole for drawing out a casting mold and disposed facing the boom, and a cover plate continuous with the bottom plate and disposed facing the arm so as to cover the draw-out hole. A projection protruding in a draw-out direction of the casting mold is formed in at least a part of an edge facing the draw-out hole, in the bottom plate, the projection having an inner peripheral wall and an outer peripheral wall with respect to the draw-out hole.