Document Document Title
US07741920B2 Quadrature oscillator with simplified amplitude, phase and frequency control
An oscillator circuit providing quadrature outputs and enabling instantaneous control over phase, frequency and amplitude of the output waveforms is disclosed. In one embodiment, the oscillator circuit comprises an oscillation loop, at least one capacitor switching circuit coupled to the oscillation loop, and a synchronization signal having an output coupled to the at least one capacitor switching circuit. The synchronization signal may be derived internally from the oscillation loop or externally from an external oscillator.
US07741917B2 Noise shaping time to digital converter
According to an embodiment of a time to digital converter, the time difference between a signal of interest and a reference signal is measured by operating a digitally controlled oscillator at a first frequency during a first portion of the reference signal period and changing the operating frequency from the first frequency to a second frequency during the reference signal period as a function of the time difference between the signal of interest and the reference signal. The time to digital converter continuously counts how many signal transitions occur at an output of the digitally controlled oscillator during the reference signal period. The time difference between the signal of interest and the reference signal is estimated based on the number of signal transitions counted during the reference signal period.
US07741916B2 Reconfigurable circuit to compensate for a low noise amplification input matching variation and a method for its configuration
A method for changing an effective capacitance of an amplifier circuit having a match transistor and a coupled cascode transistor includes changing an on-state of at least one of a plurality of sub-transistors of the match transistor. The method further includes changing a transconductance of the match transistor as a function of the change of the on-state. The method further includes changing an equivalent resistance, as measured between a source and a drain of the cascode transistor, as a function of the change of the transconductance of the match transistor.
US07741914B1 Amplifier system with dynamically-adjusted supply voltage
An amplifier system may include an output stage configured to provide an amplified output signal at an output thereof based on an input signal, the output stage being connected between first and second supply voltages. A dynamic power supply control system provides the first and second supply voltages, the dynamic power supply being configured to adjust the first and second supply voltages as a function of the input signal such that a difference between the first and second supply voltages remains substantially constant.
US07741909B2 Linear-in-dB variable gain amplifier
A variable gain amplifier (VGA) with a gain thereof exponential to a control voltage thereof. The variable gain amplifier (VGA) comprises an exponential DC converter, and a linear voltage multiplier. The exponential DC converter receives the control voltage and generates an exponential voltage which is exponential to the control voltage. The linear voltage multiplier is coupled to the exponential DC converter and has a gain proportional to the exponential voltage of the exponential DC converter.
US07741903B2 Distortion-driven power amplifier power supply controller
A power amplifier controller measures the distortion of a power amplifier output. Based upon the distortion measured, the supply voltage to the PA is adjusted in a control loop. In one embodiment, distortion is measured by computing the ratio of the measured power in the output frequencies outside the desired output channel to the measured power in the output frequencies within the desired channel. If the distortion measured from the PA is higher than a target distortion level, the power supply voltage is raised. If the distortion measured from the PA is lower than the target distortion level, the power supply voltage is reduced. Thus, the supply voltage to the PA is maintained at the lowest possible voltage level, improving the efficiency of the PA.
US07741901B2 Circuit for charging a bootstrap capacitor in a voltage converter
For charging a bootstrap capacitor in a voltage converter, a circuit is provided for wider bandwidth to eliminate the feedback stability issue and pin out for compensation circuit. A pair of transistors are connected in series between a power input and the bootstrap capacitor, the first transistor is switched synchronously with a low-side transistor of the voltage converter, and a comparator compares a feedback voltage drawn from a feedback node between the pair of transistors with a reference voltage, to control the second transistor to determine to charge the bootstrap capacitor.
US07741900B1 Bias setting device
A biasing device can supply a bias voltage to bias-able element by coupling a bias circuit to the bias-able element, coupling a state adjusting device to the biasing circuit, configuring the state adjusting device to 1) increase an initial biasing voltage by a first amount when an intermediate voltage threshold exceeds a voltage drop across the bias-able element and 2) increment the increased initial bias voltage by a second amount, where the second amount is a fraction of the first amount, until the voltage drop across the bias-able element substantially equals a predetermined bias voltage. The bias circuit of the biasing device can include a variable resistance, which is controlled by the state adjusting device and configured to vary the biasing voltage, in series with the bias-able element. The variable resistance can include a first variable resistance coupled in series to a first terminal of the bias-able element and a second variable resistance coupled in series to a second terminal of the bias-able element.
US07741899B2 Step-up power supply circuit and stepping-up method
Boosting operation of a charge pump is performed at a fixed period irrespective of the state of a load. A regulator for controlling a charge pump includes: a frequency dividing circuit generating a frequency-divided clock having a period that is twice that of a boost clock; a voltage dividing circuit generating a plurality of divided voltages having voltage values that differ from one another; a comparator circuit comparing each of the divided voltages and a reference voltage and outputting a plurality of comparison-result signals; a selection signal generating circuit reading in logic of each of the comparison-result signals in synch with an edge of the frequency-divided clock and outputting selection signals; a duty converting circuit outputting a plurality of clocks having different ON duties; a selector selecting any one of the plurality of clocks or “H”-level logic as a PWM signal based upon the selection signals; and a gate circuit taking the logical AND between the frequency-divided clock and the PWM signal and generating control signals for controlling series-parallel switching.
US07741895B2 Semiconductor switch circuit having MOS transistors with low current consumption
A semiconductor switch circuit is provided that enables current consumption to be reduced even in a conduction state. A semiconductor switch circuit 100 has P-type MOS transistors Q101 and Q102 for conduction that share a source and are connected in series between an input/output terminal 101 and input/output terminal 102, a P-type MOS transistor Q103 and N-type MOS transistor Q105 having drains connected to the gate of Q101, a P-type MOS transistor Q104 and N-type MOS transistor Q106 having drains connected to the gate of Q102, and a control terminal 103 connected to the gates of the transistors. Further semiconductor switch circuit 100 is configured with the sources and back gates of Q103 and Q104 connected to the sources of Q101 and Q102. Therefore, it is possible to switch the path between input/output terminal 101 and input/output terminal 102 between a conduction state and non-conduction state by means of voltage control by voltage value Vcont of a control signal applied to control terminal 103.
US07741887B2 Triangular wave generator
Triangular wave oscillation circuits generate A-wave and B-wave with phases opposite to each other, and are capable of independently controlling oscillation levels of the A-wave and the B-wave. A slope switching circuit including an output voltage monitoring circuit, a slope switching control circuit, and an inverter, monitors output voltages of the triangular wave oscillation circuits, to switch an output voltage generation mode of one triangular wave oscillation circuit whose triangular wave reaches a high level, from an up-slope waveform mode to a down-slope waveform mode, and to switch an output voltage generation mode of the other triangular wave oscillation circuit, from the down-slope waveform mode to the up-slope waveform mode. An oscillation level control circuit controls an oscillation level of the other triangular wave oscillation circuit so that the output voltage of the other of the triangular wave oscillation circuit becomes a reference lower limit crest value during the switching.
US07741886B2 Frequency divider
A frequency divider including a first frequency-dividing unit, a second frequency-dividing unit, a selecting unit, and a counting unit is provided. The first frequency-dividing unit receives an input signal and divides a frequency of the input signal for outputting a plurality of phase signals, wherein phases of the phase signals are mutually different. The selecting unit is connected to the first frequency-dividing unit for selecting one of the phase signals according to a control signal, so as to output an inner signal. The second frequency-dividing unit is coupled to the selecting unit for dividing a frequency of the inner signal to serve an output signal. The counting unit is coupled to the selecting unit for counting the inner signal and outputting a counting result as the control signal. Therefore, the output signal with about 50% duty cycle can be provided.
US07741884B2 Load drive circuit
A load drive circuit which can operate at high speed with low consumption current while performing the gate-to-source over voltage protection for its load driving field-effect transistor. A Zener function device is connected between the gate and the source of the load driving field-effect transistor, and an on/off-switch circuit to supply either on-potential or off-potential to the gate of the field effect transistor is provided. The current flowing through the Zener function device when the load driving field-effect transistor is conductive is limited by the on/off-switch circuit.
US07741881B2 MOSFET gate interface
In some embodiments a power circuit includes a driver output, a MOSFET, and circuitry to ensure a full and fast positive drive to a gate of the MOSFET when the driver output goes to a high signal level, and to ensure a full and fast low negative drive to the gate of the MOSFET when the driver output goes to a low signal level. Other embodiments are described and claimed.
US07741878B2 Semiconductor integrated circuit with leakage current suppressed
In a semiconductor integrated circuit, a cell arrangement area is provided on a semiconductor substrate to allow a plurality of basis cells to be arranged. A basic power supply line is provided in an upper layer than the cell arrangement area to supply a power. A switch cell is configured to control the power supply from the basic power supply line to an inside of the cell arrangement area. An always operating cell is arranged in the cell arrangement area adjacently to the switch cell, and is configured to receive the power from the switch cell even when the switch cell stops the power supply to the cell arrangement area.
US07741873B2 Receiver circuitry for receiving reduced swing signals from a channel
A receiver for receiving a reduced swing signal from a transmission channel is disclosed, in which the swing of the reduced swing signal is less than the power supply of the receiver and possibly is less than the power supply of the transmitter. The receiver comprises a level shifter for offsetting the reduced swing signal, and an amplifier which receives both the reduced swing signal and its offset to produce a full swing signal output referenced to the power supply of the receiver. The full swing signal can thereafter be buffered, and eventually can be captured by a clock. Optionally, the disclosed reduced swing receiver also contains calibration circuitry for improving the integrity of the full swing signal output, and in particular for countering the effects of process, and in some embodiments temperature, variations, which alter the characteristics of the transistors which make up the receiver circuitry. More particularly, the calibration circuitry compensates for the unbalanced way in which process and temperature variations impact transistors of differing polarities (e.g., n-type and p-type).
US07741872B2 Level shifter
A level shifter for shifting an input signal to an output signal. The level shifter includes an input buffer biased a first voltage and a ground voltage; an output buffer and a level-processing unit both biased between a second voltage and the ground voltage; and a voltage-drop unit coupled to the level-processing unit and biased between the first voltage and the second voltage. While the first voltage is in an OFF state and the second voltage is switched on, the voltage-drop unit provides an initializing voltage for the level-processing unit according to the second voltage to shift the input signal to provide the output signal.
US07741869B2 Low power consumption MIS semiconductor device
A logic gate is constructed of an insulated gate field effect transistor (MIS transistor) having a thin gate insulation film. An operation power supply line to the logic gate is provided with an MIS transistor having a thick gate insulation film for switching the supply and stop of an operation power source voltage. A voltage of the gate of the power source switching transistor is made changing in an amplitude greater than an amplitude of an input and an output signal to the logic gate. Current consumption in a semiconductor device configured of MIS transistor of a thin gate insulation film can be reduced and an power source voltage thereof can be stabilized.
US07741866B2 Load-aware circuit arrangement
The present invention relates to a circuit arrangement and method of controlling power consumption of the circuit arrangement, wherein a load applied at a circuit component is determined and the drive capacity of the circuit component is adjusted responsive to the determination result. In particular, the circuit component is tailored to have just sufficient drive capacity depending on the potential load which may be determined by examining a configuration information loaded to the circuit arrangement. Tailoring for sufficient drive can be achieved either by varying the size or number of circuit components or by adjusting the threshold voltage of circuit elements, or by doing both. Thereby, power consumption can be reduced when circuit components are driven at loads lower than the worst case load.
US07741865B1 Soft error upset hardened integrated circuit systems and methods
In one embodiment, a programmable logic device includes a plurality of configuration cells that store configuration data, wherein the programmable logic device is adapted to provide soft error upset (SEU) protection for the configuration cells that are reprogrammable. The programmable logic device may further include or alternatively provide hard coding and/or hard encoding of the configuration cells.
US07741852B2 Ionization vacuum gauge
An ionization vacuum gauge which has at least three electrodes of a grid (2), an electron source (3) and an ion collector (1) in a vacuum vessel (4) connected in communication with a vacuum apparatus, oscillates electrons emitted front the electron source (3) within and outside of the grid (2), ionizes gas molecules flying into the grid (2) by the oscillated electrons, supplements the ionized ions by the ion collector (1) to convert into a current signal, and measures a gas molecular density (pressure) in the vacuum apparatus according to the obtained current intensity, wherein the ion collector (1) is provided with a heating device for heating the ion collector.
US07741851B2 Potential measuring apparatus
A potential measuring apparatus has a detection electrode on which an electric charge is induced according to a potential of a detection object, and a modulator for altering the generated quantity of the electric charge. The detection electrode has at least one depressed portion on a surface opposite to the detection object.
US07741850B2 Electric potential measuring apparatus, and image forming apparatus
An electric potential measuring apparatus including a substrate disposed facing a measurement object, a detecting electrode provided insulated from the substrate, and a capacity modulating unit for modulating a coupling capacity between the detecting electrode and the measurement object. In the electric potential measuring apparatus, a region with a dielectric constant less than a dielectric constant of the substrate is formed in the substrate to achieve an increase in resistivity of a portion of the substrate between detecting electrodes, or a decrease in a stray capacity between the detecting electrode and the substrate.
US07741848B1 Adaptive multichannel locator system for multiple proximity detection
A man-portable locator system for locating buried or otherwise inaccessible pipes, conduits, cables, wires and inserted transmitters using detector arrays and stochastic signal processing and similar techniques to analyze and display multiple target objects at differing frequencies in a layered user interface (UI). For example, the locator UI may be adapted to present a target plurality sorted by proximity of target conductor to the locator operator together with other useful information specifying the multiple objects, frequencies and changes in the subterranean landscape by means of a useful combination of graphical, numeric and acoustic representations.
US07741841B2 Time-lapsed diffusivity logging for monitoring enhanced oil recovery
The use of time-lapsed NMR diffusivity measurements in an observation well is disclosed. The observation well is cased in the zone of interest with non-magnetic and non-conductive casing that is invisible to the NMR tool. Second, because NMR measurements have a dead zone in front of the antenna depending on the spatial variation of the fixed magnet strength, for example about 2.7 inches, a distance between the casing and the formation is reduced to less than the dead zone length by drilling the observation well at small deviation of about 5° and running the casing without centralizers. Both the casing and the pad-type NMR tool will follow the low side of the borehole, ensuring the measurement volume of the NMR tool is inside the formation and beyond the annulus. With the appropriate observation well completion, time-lapse diffusivity measurements with pad-type NMR tools can address several shortcomings in the current practice of monitoring EOR processes that rely upon changes in density and hydrogen index (HI). Various uses of NMR imaging in wells cased with non-metallic casing are also disclosed.
US07741838B2 Rotation detecting device and anti-skid braking system using the same
A rotation detecting device that includes an electric power generator having a stator and a rotor, said rotor having a plurality of alternating opposite magnetic poles in a circumferential direction of the rotor, at least a first magnetic sensor mounted on either the stator or a support member for supporting the stator and operable to detect the alternating opposite magnetic poles in the rotor; and an electric power supply circuit for utilizing an electric power generated by the electric power generator as an electric power source for the at least first magnetic sensor.
US07741836B2 Test tray transferring apparatus for a test handler, test handler, and method of transferring test trays for a test handler
A test handler is disclosed. First and second gripping blocks for respective front and rear test trays to be transferred along a circulation path move together in a circulation direction, but move independently in a direction perpendicular to the circulation path and grip and release independently. The test trays can be transferred by a single power source and interference between an assisting a test and a transferring can be minimized.
US07741835B2 Electric meter having a detachable measuring bar
An electric meter having a detachable measuring bar includes a main body, a first measuring bar and a second measuring bar assembly. One end of the main body is formed with a supporting portion. The first measuring bar has a connecting portion and a probe formed at the other end of the connecting portion. The connecting portion is detachably connected with the supporting portion of the main body. The second measuring bar assembly comprises a second measuring bar and a lead. Both ends of the lead are connected to the main body and the second measuring bar. Via this arrangement, when the first measuring bar is worn or damaged in use, the first measuring bar can be replaced, thereby reducing the purchasing cost of the electric meter.
US07741829B2 Subsystems and methods for use in patch clamp systems
Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.
US07741826B1 Device and method for compensating for ground voltage elevations
A method and a device, the device has ground voltage elevation compensation capabilities and includes: multiple current consuming components; a positive voltage supply input; a negative voltage supply input; and a compensation circuit, coupled to the negative voltage supply input and to a grounding element; wherein the compensation circuit is adapted to detect a ground voltage elevation resulting from a flow of excess consumption current through the grounding element, and in response couple the negative voltage supply input to the grounding element; wherein the excess current flows through the grounding element due to an increment in a current consumption of a current consuming element of the device.
US07741822B2 DC-DC converter
The invention provides DC-DC converters comprising a load sensor, a variable Power MOS, and a Power MOS width controlling and driving device. The Power MOS width controlling and driving device is coupled between the load sensor and the variable Power MOS. The variable Power MOS comprises a plurality of PMOS transistors coupled in parallel and a plurality of NMOS transistors coupled in parallel. After the load sensor detects the load current of the DC-DC converter, the Power MOS width controlling and driving device conducts the PMOS and NMOS transistors according to the sensed load current to control the total size of the conduction paths that couple a transformed DC voltage output terminal to a source of an original DC voltage or ground.
US07741821B2 Start-up circuit and method for high voltage power distribution circuit
A start-up circuit for a high voltage power distribution circuit includes a transistor, a current source which generates ramped current, an operational amplifier which is connected between the current source and the transistor and controls the transistor, a capacitor which is fed the generated ramped current from the current source and is charged by the generated ramped current, the capacitor being connected to the non-inverting input of the operational amplifier, and a feedback capacitor connected from the transistor output to the non-inverting input of the operational amplifier, which is fed the generated ramped current from the capacitor and is discharged. The transistor is fully enabled when the feedback capacitor is fully discharged.
US07741814B2 Power supply device
A power supply device includes battery equipment and voltage detecting circuitry. The battery equipment includes positive-side and negative-side battery blocks that are connected to each other at a reference midpoint. The voltage detecting circuitry detects the respective voltage values of serially-connected battery modules of the battery equipment. The voltage detecting circuitry includes positive-side and negative side voltage management ICs with respect to the reference midpoint. The positive-side and negative side voltage management ICs manage the voltage conditions of the battery modules in the positive-side and negative-side battery blocks, respectively. Positive-side and negative-side voltage power lines of each of the positive-side and negative side voltage management ICs are connected to positive-side and negative-side output terminals of the battery equipment so that all the battery modules supply electric power to each of the voltage management ICs. The voltage management ICs have a common ground line.
US07741813B2 Method and system for managing battery inventory
Provided are a method and a system for inventorying batteries. In exemplary embodiments, a computer assisted method for inventorying batteries includes identifying a battery string at a location and reading battery identification data associated with one or more batteries in the battery string which includes a battery voltage. After reading the battery identification data and aggregating the magnitudes of the battery voltages in the battery string, if the aggregate of the magnitudes of the voltages is not equal to a required voltage then an error message is generated. If the aggregate of the voltages of the batteries is equal to the required voltage then the process may be repeated for the next string, if any, at the location.
US07741812B2 Battery charging apparatus including notification control unit
An electronic apparatus including: a battery; a notification unit; a storage unit that stores a reference charging time and a reference battery voltage which are values according to charging characteristics of the battery and are used as determination reference values to determine whether or not the battery is normally charged; a charged state determination unit that determines whether or not the charging voltage is applied to the battery; a voltage detection unit that detects a voltage of the battery; and a notification control unit that controls the notification unit to make a notification indicating an abnormal state, when the voltage of the battery detected by the voltage detection unit does not reach the reference battery voltage, even though a condition where the charged state determination unit determines that the charging voltage is applied to the battery continues for the reference charging time.
US07741811B2 Capacitor charging control circuit
A parallel monitor circuit having a simple circuit configuration, in which a voltage divider circuit can be formed with resistors having the same resistance value, includes plural capacitors are connected in series, and a bypass device of each of parallel monitor circuits is connected in parallel with each capacitor. Plural voltages Va different from one another by a constant voltage are sequentially outputted from a digital-to-analog converter, and the voltages Va are inputted to plural parallel monitor circuits. When a charging voltage is higher than a monitor voltage determined by the voltage Va, each capacitor discharges through the bypass device, and the capacitor is kept at a predetermined monitor voltage.
US07741809B2 Electrical component including a battery receptacle for including a battery
An electrical component, such as, for example, a radio, an audio component, a battery charger or a radio/charger, is provided. The electrical component includes a housing and an electrical circuit supported by the housing. In some aspects, the electrical component is an audio component and the electrical circuit is an audio circuit. In other aspects, the electrical component is a battery charger and the electrical circuit is a charging circuit. In yet other aspects, the electrical component may define a receptacle capable of selectively receiving batteries of different heights. In further aspects, the electrical component may support a battery inclined relative to a surface upon which the battery sits.
US07741804B2 Man-powered slim charger
A human-powered slim charger utilizing an axial flux alternator for converting a pull-out motion into an electrical current for charging and supplying battery-fed electronic devices. The charger comprises mechanical transmission means for converting a periodic linear movement into a unidirectional rotation, an axial flux alternator comprising a stator comprising a planar winding, having a plurality of coils embedded in multiple layers within said stator and circularly distributed around a central axis and two essentially identical rotors arranged to rotate together around said central axis and allocated concentrically with said winding on both sides of said stator facing each other; wherein each said rotor comprises a periodical heteropolar axially magnetized magnetic system having a definite number of poles; Finally, the device comprises a charging control module affixed to the stator, said control module configured effectively convert non-stable alternating current produced by said alternator into a charging direct current.
US07741799B2 Brushless direct current motor driving circuit
A brushless DC motor drive circuit includes a drive unit and a transient current suppression circuit. The drive unit comprises a Hall component, a drive component, a first transistor and a second transistor. The Hall component detects the position of a rotor of the DC motor and transmits digital command signals to the drive component; the drive component further generates two complementary digital command signals; and the first and second transistors connect with the drive component respectively. The transient current suppression circuit comprises a first auxiliary transistor and a second auxiliary transistor, wherein the first auxiliary transistor receives one of the complementary digital command signals different from the other one received by the first transistor and the second auxiliary transistor receives the other one of the complementary digital command signals different from the one received by the second transistor.
US07741798B2 RFI/EMI filter for variable frequency motor drive system
An RFI/EMI filter for a variable frequency motor drive system includes a variable frequency drive; a common mode choke; a motor; a cable including a plurality of power leads interconnecting the motor with the variable frequency drive and passing through the choke; a ground shield surrounding the cable and connected to motor ground and variable frequency drive ground; and a common mode return conductor interconnected between the variable frequency drive and the motor and disposed within the shield and passing through the choke for returning a portion of the common mode current to cancel a portion of the saturation current experienced by the choke to increase the portion of the common mode current carried by the return conductor and decrease the portion carried by the shield to reduce the RFI/EMI contributed by the shield.
US07741793B2 Hybrid electric device
A device includes a housing configured with a working element. The device further includes a motor configured for urging motion of the working element. The device further includes a power control module. The power control module is configurable for being in electrical connection with at least one of the motor, a first power source configuration and a second power source configuration. The first power source configuration is configurable for being electrically connected to a battery assembly having a DC power output. The second power source configuration is configurable for being electrically connected to a power inverter, the power inverter configured for receiving an AC power and further configured for outputting a DC power to the second power source configuration. The motor receives power via the power control module from the first power source configuration and/or the second power source configuration.
US07741792B2 Motor control device
A motor control device includes: a motor that has a plurality of rotors which respectively have a magnetic piece, which drives or supplementarily drives a vehicle; a phase changing mechanism that changes relative phases of the plurality of rotors, and sets these to a predetermined induced voltage constant; and a speed control device that controls a phase changing speed of the phase changing mechanism.
US07741791B2 High pressure discharge lamp control method
A system for providing a controllable current to a high intensity discharge lamp is provided. The system includes a current controller that is configured to receive input power and to provide an output current waveform to the high intensity discharge lamp. This current causes a discharge of light from the lamp. The output current waveform includes an absolute value amplitude in each half cycle that is generally constant during a first portion and that which increases non-linearly from the generally constant amplitude to a peak amplitude during a second portion.
US07741788B2 Light emitting apparatus with current limiting
In conduction of light emitting diodes LEDs 1 to 4, a switching signal 101 is converted into a voltage V2 or 0V through a signal converter 26 in accordance with a logic level thereof. The voltage obtained by the conversion is compared with a voltage V1 on both ends of a resistor R1 through an operational amplifier 20 to open/close an output loop by an NMOS transistor 22, a current If of the light emitting diodes LEDs 1 to 4 is limited to a current If1 so as not to exceed a maximum current, and a current defined with an ON duty of the switching signal 101 is caused to flow as a mean current to the light emitting diodes LEDs 1 to 4 to inhibit an overshoot current from flowing to the light emitting diodes LEDs 1 to 4 while the output loop is closed.
US07741787B2 Light-emitting diode driving circuit
A light-emitting diode driving circuit includes a control circuit, a transistor switch and a compensating circuit. The control circuit receives an oscillating signal to generate a pulse drive signal. The transistor switch is activated by the pulse drive signal such that an inductor is charged by an input voltage, in which the inductor is arranged to deliver an inducting current to at least one light-emitting diode when the transistor switch is deactivated. The compensating circuit is coupled between the control circuit and a capacitor provided for reducing ripples of an output voltage corresponding to the inducting current. The compensating circuit performs a charging and discharging operation along with the capacitor when controlled by a dimming control signal provided to control brightness of the light-emitting diode.
US07741786B2 Lighting control with season detect
An outdoor lighting control method and apparatus for use with an outdoor lighting fixture that automatically detects the changing length of the day and provides for automatically turning off the light after a shorter period of illumination during shorter summer nights and after a longer period of illumination during longer winter nights. The control method measures the elapsed time interval over which night sets in, for example, by sensing light levels characteristic of the onset of dusk and the onset of night and measuring the elapsed time between the two sensed light levels, and then automatically turns on the lighting fixture for nighttime operation for a duration that depends on the measured elapsed night-onset time.
US07741785B2 Method and device for dimming lighting control devices to a predefined level
A method for driving an electronically controlled lighting means operating device, by evaluating an output signal of a motion sensor which is connected to a supply voltage and outputs the supply voltage as an output signal as a function of the detection of a motion, and setting the electronically controlled lighting means operating device to one of a plurality of predetermined dimming levels as a function of an output signal of the motion sensor. At least one of the predetermined dimming levels is programmed or the output signal of the motion sensor is detected at a control input of a digital interface of the operating device.
US07741783B2 Microwave generator
A microwave generator has at least one resonator with two mutually opposite resonator electrodes which are separated by a spark gap. The spark gap breaks down when a high-voltage is applied. The resonator electrodes are designed in the area of the spark gap such that they result in a two-dimensional or three-dimensional section with a substantially constant, minimum electrode separation.
US07741780B2 Ceramic discharge vessel having a sealing composition
A sealing composition for ceramic discharge vessels is described. The sealing composition contains about 20 to about 40 mole percent MgO, about 20 to about 45 mole percent Y2O3, and about 20 to about 60 mole percent Al2O3 and has a melting point of less than about 1800° C., and preferably from about 1700° C. to about 1800° C. The sealing composition may be used for making ceramic-to-ceramic or ceramic-to-metal seals in ceramic discharge vessels.
US07741777B2 Display panel and manufacturing method of the display panel
A PDP includes a guide partition (127) that extends substantially along a center line F between a pair of first partitions (125) at a position spaced apart from an end of the nearest first partition (125) by a distance H. In a phosphor forming step, a phosphor paste is initially applied on the guide partition (127) by a nozzle (200), which has been located above the guide partition (127). Then, the nozzle (200) is moved to provide a phosphor layer whose end is formed on the guide partition (127).
US07741775B2 Electro-optical device and electronic device
An object of the present invention is to provide an EL display device having a high operation performance and reliability.The switching TFT 201 formed within a pixel has a multi-gate structure, which is a structure which imposes an importance on reduction of OFF current value. Further, the current control TFT 202 has a channel width wider than that of the switching TFT to make a structure appropriate for flowing electric current. Morever, the LDD region 33 of the current control TFT 202 is formed so as to overlap a portion of the gate electrode 35 to make a structure which imposes importance on prevention of hot carrier injection and reduction of OFF current value.
US07741773B2 Thick film dielectric structure for thick dielectric electroluminescent displays
An improved smoothing layer for use with a thick film dielectric layer, and improved composite thick film dielectric structure is provided. The smoothing layer is a piezoelectric or ferroelectric material that has a reduced amount of defects. The smoothing layer is formed by the addition of surfactant to a sol gel or metal organic solution of organo metallic precursor compounds. The composite thick film dielectric structure comprises a thick film dielectric composition having a PZT smoothing layer thereon, the smoothing layer being made by a process incorporating surfactant. Both the smoothing layer and the composite thick film dielectric structure are for use in electroluminescent displays.
US07741764B1 DLC emitter devices and associated methods
Diamond-like carbon field emission surfaces, including associated devices and methods for using such devices are disclosed. In one aspect, for example, a field emission surface is provided, including a smooth layer of diamond-like carbon disposed on a smooth substrate, the diamond-like carbon layer having a uniformly distributed ablation pattern configured to emit electrons. The diamond-like carbon layer should be smooth in order to allow the uniform distribution of the ablation pattern.
US07741755B2 Recess-protrusion structure body, process for producing the same, piezoelectric device, and ink jet type recording head
In a step (A), a selectively removable resist layer or a selectively removable sacrifice layer is formed in a predetermined pattern in a protrusion non-forming region on a base plate. In a step (B), a pillar-shaped structure film is formed on a side of the base plate, on which side the resist layer or the sacrifice layer has been formed in the predetermined pattern. The pillar-shaped structure film contains a plurality of pillar-shaped bodies, each of which extends in a direction nonparallel with a base plate surface of the base plate. In a step (C), the resist layer or the sacrifice layer, and a region of the pillar-shaped structure film, which region is located on the resist layer or the sacrifice layer, are removed by use of a lift-off technique. At least one protruding region, which contains the pillar-shaped bodies, is thus formed.
US07741753B2 Megasonic apparatus, circuitry, signals and methods for cleaning and/or processing
The invention utilizes multiple frequency megasonic generators driving multiple frequency harmonic transducers. Generator signals that increase cavitation efficiency and that have successive time periods with predominantly stable cavitation and predominantly transient cavitation further improve the performance of the cleaning, microbiological inactivation, sonochemistry or processing systems. Probes that monitor the megasonics and feedback the information to the generator provide consistency of process.
US07741749B2 Inner cross over support clip
An inner crossover support clip may be used to support a crossover wire joining two adjacent rotor coils on a rotating machine, such as a generator. The support clip of the present invention may be capable of withstanding forces, such as centrifugal forces, that lead to the failure of conventional crossover wires. The support clip may be formed of a sheet material bent at an angle to form an inside surface thereon and may include a tie edge formed on each end of the sheet material. The tie edge attaches to adjacent rotor coils of a rotating machine and the inside surface supports a crossover wire electrically connecting the adjacent rotor coils.
US07741746B2 Magnetic torque limiter
A magnetic slip clutch has an outer rotor and an inner rotor, one of the rotors includes permanent magnets, and one of the rotors includes slots, and both rotors are located coaxially to one another; the outer rotor is embodied as a hollow cylinder open on one end, which cylinder includes a face-end covering with a central recess, by which the hollow cylinder can be located on a shaft, and the inner rotor is embodied as a solid cylinder, which is located inside the outer rotor, and a shaft can be located in a central recess in the solid cylinder, and a separate shaft is connectable to each rotor, so that the axis of rotation of the two separate shafts is identical, and a torque transmission is possible from one shaft to the other shaft by both rotors.
US07741742B2 Alternator
A vehicular alternator is provided which can suppress the vibration of a circuit board. The vehicular alternator has a rectifier that includes a plurality of diodes forming a full-wave rectifier circuit, a pair of negative and positive terminal side heat sinks that hold the diodes, and a circuit board connecting the diodes and a stator coil to one another, wherein the negative and positive terminal side heat sinks and the circuit board are mounted on a casing at a plurality of mounting portions, which are superposed with one another in an axial direction of a shaft, by using mounting members. Between adjacent ones of the mounting portions, there are formed abutment portions in which the circuit board is superposed on and placed in abutment with the negative terminal side heat sink or the positive terminal side heat sink, and the abutment portions are fixed to each other by rivets.
US07741741B2 Drive apparatus for a washing machine
A drive apparatus for a washing machine includes an electric motor, a drive shaft connected to the electric motor for rotary drive, a fan for cooling the electric motor and electronics for controlling operation of the electric motor. In order to achieve a compact construction, the electric motor and the electronics are integrated in a common unit, such as a motor housing. In order to protect the electronics and at the same time ensure that the electronics are sufficiently cooled, the common unit has a dividing wall, with the electric motor and a printed circuit board of the electronics disposed on opposite sides of the dividing wall. The dividing wall has at least one aperture. The electronics include power components protruding at least partially through the aperture and being in contact with the dividing wall and/or with a cooling air stream generated by the fan.
US07741740B2 Gas-cooled electrical device
The invention relates to a gas-cooled electrical device (13), especially a gas-cooled generator, which comprises at least a rotor (1), a stator (2) and also a stator casing (3) which encloses this stator, and an end-winding space (5). In this case, passages for a cooling gas are provided both in the rotor (1) and in the stator (2), wherein the end-winding space (5), especially connectors (7) and/or output conductors (7) which are arranged therein, are impinged by at least some of the cooling gas flow (8) which issues from the rotor (1). In order to be able to achieve an especially concentrated and controlled cooling, at least the connectors (7) and the output conductors (7) are arranged in the working area of at least one guiding device (14) which guides the cooling gas flow (8).
US07741739B2 Automotive alternator
A cooling airflow introducing guide portion is disposed on a portion of a connector that faces fins of a voltage regulator heatsink so as to extend in a direction of array of the fins so as to ensure a predetermined clearance relative to the fins. An air intake aperture is disposed through a portion of the rear bracket that faces the voltage regulator heatsink.
US07741734B2 Wireless non-radiative energy transfer
The electromagnetic energy transfer device includes a first resonator structure receiving energy from an external power supply. The first resonator structure has a first Q-factor. A second resonator structure is positioned distal from the first resonator structure, and supplies useful working power to an external load. The second resonator structure has a second Q-factor. The distance between the two resonators can be larger than the characteristic size of each resonator. Non-radiative energy transfer between the first resonator structure and the second resonator structure is mediated through coupling of their resonant-field evanescent tails.
US07741725B2 Semiconductor apparatus and method of producing the same
With a semiconductor apparatus package of example embodiments of the technology disclosed herein and a method of producing the semiconductor apparatus package, the semiconductor apparatus package includes a circuit board and a semiconductor device sealed with sealing resin. The circuit board has a groove in a section of a surface of the circuit board. The section is outside of the resin sealing section, and the surface includes the resin sealing section. The groove is at least partially filled with sealing resin having seeped from a resin sealing section. Thus, in the semiconductor apparatus package including the circuit board, which is exposed from the resin sealing section, and the semiconductor device sealed on the circuit board with the sealing resin, the spread of a thin resin film onto that exposed circuit board resulting from seepage of resin sealing the semiconductor device is prevented.
US07741724B2 Semiconductor device
This invention is directed to offer a semiconductor device having a structure capable of relaxing a mechanical stress applied to a bonding pad. A third interlayer insulation film having via holes is formed on a second interlayer insulation film to cover a third wiring layer. A third conductive layer is formed in the via hole. The third interlayer insulation film is composed of an array of a plurality of hexagonal column-shaped interlayer insulation films. And the via hole and the third conductive layer are formed to surround each hexagonal column-shaped interlayer insulation film. A fourth wiring layer connected with the third wiring layer through the third conductive layer is formed. The fourth wiring layer makes an uppermost wiring layer in an embodiment of this invention and serves as the bonding pad.
US07741717B2 Metal line of semiconductor device and method of fabricating the same
A metal line of a semiconductor device comprising contact plugs, a plurality of first trenches, first metal lines, a plurality of second trenches, and second metal lines. The contact plugs are formed over a semiconductor substrate and are insulated from each other by a first insulating layer. The plurality of first trenches are formed in the first insulating layer and are connected to first contact plugs of the contact plugs. The first metal lines are formed within the first trenches and are connected to the first contact plugs. The plurality of second trenches are formed over the first metal lines and the first insulating layer and comprise a second insulating layer connected to second contact plugs of the contact plugs. The second metal lines are formed within the second trenches and are connected to the second contact plugs.
US07741714B2 Bond pad structure with stress-buffering layer capping interconnection metal layer
A bond pad structure for an integrated circuit chip has a stress-buffering layer between a top interconnection level metal layer and a bond pad layer to prevent damages to the bond pad structure from wafer probing and packaging impacts. The stress-buffering layer is a conductive material having a property selected from the group consisting of Young's modulus, hardness, strength and toughness greater than the top interconnection level metal layer or the bond pad layer. For improving adhesion and bonding strength, the lower portion of the stress-buffering layer may be modified as various forms of a ring, a mesh or interlocking-grid structures embedded in a passivation layer, alternatively, the stress-buffering layer may has openings filled with the bond pad layer.
US07741710B2 Module with multiple power amplifiers and power sensors
Systems and methods are disclosed for a device having one or more power amplifier and/or LNA circuits positioned on the amplifier module.
US07741706B2 Plastic surface mount large area power device
A low profile, 1 or 2 die design, surface mount high power microelectronic package with coefficient of expansion (CTE) matched materials such as Silicon die to Molybdenum conductor (bond pads). The CTE matching of the materials in the package enables the device to withstand repeated, extreme temperature range cycling without failing or cracking. The package can be used for transient voltage suppression (TVS), Schottky diode, rectifier diode, or high voltage diodes, among other uses. The use of a heat sink metal conductor that has a very high modulus of elasticity allows for a very thin wall plastic locking to be utilized in order to minimize the footprint of the package.
US07741705B2 Semiconductor device and method of producing the same
A semiconductor device includes a semiconductor substrate having an internal circuit; an electrode pad electrically connected to the internal circuit; an insulating film having a through hole exposing the electrode pad; and a re-distribution wiring pattern formed on the insulating film and electrically connected to the electrode pad. The semiconductor device further includes a recess groove formed in the insulating film around and adjacent to the re-distribution wiring pattern.
US07741704B2 Leadframe and mold compound interlock in packaged semiconductor device
An interference interlock between leadframe features and a mold compound is provided in a packaged semiconductor device by exposing at least one predetermined surface area to an etching process prior to a molding step. This produces an etched recess with a recessed wall delimited by a step wall, generally perpendicular and adjacent to the recessed wall. The step wall is partially undercut by etching. During the molding step, the recessed wall and the step wall are both contacted by and embedded in the molding compound.
US07741699B2 Semiconductor device having ultra-shallow and highly activated source/drain extensions
A semiconductor device includes a gate stack over a semiconductor substrate, a lightly doped n-type source/drain (LDD) region in the semiconductor substrate and adjacent the gate stack wherein the LDD region comprises an n-type impurity, a heavily doped n-type source/drain (N+ S/D) region in the semiconductor substrate and adjacent the gate stack wherein the N+ S/D region comprises an n-type impurity, a pre-amorphized implantation (PAI) region in the semiconductor substrate wherein the PAI region comprises an end of range (EOR) region, and an interstitial blocker region in the semiconductor substrate wherein the interstitial blocker region has a depth greater than a depth of the LDD region but less than a depth of the EOR region.
US07741696B2 Semiconductor integrated circuit including metal mesh structure
A metal mesh structure for use in an integrated circuit is described. In one embodiment, a semiconductor integrated circuit includes a first region including, for example, a device layer having one or more active semiconductor devices. The circuit also includes a second region, which may include a metalization layer including circuit wires. The circuit further includes a layer of metal mesh interposed between the first and second regions, and which may be implemented on at least a portion of another metalization layer.
US07741691B2 Semiconductor photodetector
A semiconductor photodetector includes a semiconductor substrate of a first conductivity type, a light absorption layer of the first conductivity type on the semiconductor substrate and absorbing light, a diffraction grating layer on the light absorption layer and including a diffraction grating diffracting light, a first light transmissive layer of a second conductivity type on the diffraction grating layer and transmitting light, and a second light transmissive layer of the first conductivity type on the diffraction grating layer and surrounding the first light transmissive layer, the second light transmissive layer transmitting light. The diffraction grating surrounds a region of the diffraction grating layer that is directly below the first light transmissive layer.
US07741687B2 Microstructure, semiconductor device, and manufacturing method of the microstructure
A microstructure includes a first structural layer and a second structural layer which faces the first structural layer with a space interposed therebetween and is partially fixed to the first structural layer. At least one of the first structural layer and the second structural layer can be displaced. Further, opposed surfaces of the first structural layer and the second structural layer are different in roughness.
US07741685B1 Method and apparatus for an actuator system having buried interconnect lines
A micromachined actuator including a body or platform mounted to a suspension system anchored to a substrate. In one embodiment, the suspension system is comprised of a set of one or more spring flexures connecting the actuator body to the substrate with strain relief provided via connecting torsional elements. In another embodiment, the suspension system includes a first set of one or more spring flexures each with one end anchored to a largely rigid intermediate frame and the other end attached to the body. A second set of one or more flexures is attached between the intermediate frame and the substrate. A third actuator embodiment maximizes force electrode area to minimize voltage required for electrostatic actuation. A fourth embodiment provides electrical interconnect to an actuator or an actuator array using polysilicon with silicon nitride isolation. Actuators may be fabricated by combining the key features of all four embodiments or actuators may be fabricated using any combination of two or three of the embodiments.
US07741683B2 Semiconductor device
A semiconductor device is disclosed. Embodiments relate to a semiconductor device which includes an active region including a source region, a drain region, and a channel region. A gate electrode, source electrodes, and a drain electrode are formed around the active region. A plurality of gate fingers diverge from the gate electrode into the channel region. A plurality of source fingers diverge from the source electrodes into the source region, the source fingers being disposed between the gate fingers in a predetermined pattern, the source fingers having at least two finger lines connected to each other via at least one grid line. A plurality of drain fingers diverge from the drain electrode into the drain region, the drain fingers being disposed between the gate fingers where the source fingers are not disposed.
US07741671B2 Capacitor for a semiconductor device and manufacturing method thereof
Disclosed is a capacitor for a semiconductor device, comprising: a lower electrode formed over a predetermined lower structure on a semiconductor substrate; an aluminum oxynitride film formed over the lower electrode and having a low leakage current characteristic; a yttrium oxynitride film formed over the aluminum oxynitride film and having a higher dielectric constant than the aluminum oxynitride film; and an upper electrode formed over the yttrium oxynitride film, and a manufacturing method thereof.
US07741669B2 Nonvolatile memory cells employing a transition metal oxide layers as a data storage material layer and methods of manufacturing the same
Non-volatile memory cells employing a transition metal oxide layer as a data storage material layer are provided. The non-volatile memory cells include a lower and upper electrodes overlapped with each other. A transition metal oxide layer pattern is provided between the lower and upper electrodes. The transition metal oxide layer pattern is represented by a chemical formula MxOy. In the chemical formula, the characters “M”, “O”, “x” and “y” indicate transition metal, oxygen, a transitional metal composition and an oxygen composition, respectively. The transition metal oxide layer pattern has excessive transition metal content in comparison to a stabilized transition metal oxide layer pattern. Methods of fabricating the non-volatile memory cells are also provided.
US07741668B2 Nonvolatile ferroelectric memory device
A nonvolatile ferroelectric memory device is provided so as to control read/write operations of a nonvolatile memory cell using a channel resistance of the memory cell which is differentiated by polarity states of a ferroelectric material. In the memory device, an insulating layer is formed on a bottom word line, and a floating channel layer comprising a N-type drain region, a P-type channel region and a N-type source region is formed on the insulating layer. Then, a ferroelectric layer is formed on the floating channel layer, and a word line is formed on the ferroelectric layer. As a result, the resistance state induced to the channel region is controlled depending on the polarity of the ferroelectric layer, thereby regulating the read/write operations of the memory cell array.
US07741664B2 Complementary metal oxide semiconductor image sensor and method for fabricating the same
Provided are a CMOS image sensor and a method for fabricating the same. A nanopillar is plurally formed at an upper end of a light receiving element.
US07741663B2 Air gap spacer formation
Miniaturized complex transistor devices are formed with reduced leakage and reduced miller capacitance. Embodiments include transistors having reduced capacitance between the gate electrode and source/drain contact, as by utilizing a low-K dielectric constant sidewall spacer material. An embodiment includes forming a gate electrode on a semiconductor substrate, forming a sidewall spacer on the side surfaces of the gate electrode, forming source/drain regions by ion implantation, forming an interlayer dielectric over the gate electrode, sidewall spacers, and substrate, and forming a source/drain contact through the interlayer dielectric. The sidewall spacers and interlayer dielectric are then removed. A dielectric material, such as a low-K dielectric material, is then deposited in the gap between the gate electrode and the source/drain contact so that an air gap is formed, thereby reducing the parasitic “miller” capacitance.
US07741655B2 Semiconductor device
A semiconductor device includes a semiconductor substrate having a main surface and a semiconductor element having an insulated gate field effect portion formed in the semiconductor substrate. The semiconductor element includes an n− region, an n-type source region, a p-type base region, an n+ region, and a gate electrode. The n− region and the n-type source region are formed in the main surface. The p-type base region is formed in the main surface adjacent to the n-type source region. The n+ region is formed in the main surface adjacent to the p-type base region and opposed to the n-type source region with the p-type base region being interposed, and has an impurity concentration higher than the n− region. The n− region is formed in the main surface adjacent to the p-type base region and to the n+ region.
US07741652B2 Alignment device and application thereof
An alignment device and applications thereof are disclosed. The device comprises a dam structure disposed on a first substrate, and a post disposed on a second substrate at a position corresponding to the dam structure. The dam structure comprises a groove. The post is disposed in the groove of the dam structure when bonding the first and second substrates.
US07741648B2 Penetrating hole type LED chip package structure using a ceramic material as a substrate and method for manufacturing the same
An LED chip package structure includes a ceramic substrate, a conductive unit, a hollow ceramic casing, many LED chips, and a package colloid. The ceramic substrate has a main body, many protrusions extended from the main body, many penetrating holes respectively penetrating through the protrusions, and many half through holes formed on a lateral side of the main body and respectively formed between each two protrusions. The conductive unit has many first conductive layers respectively formed on the protrusions, many second conductive layers respectively formed on inner surfaces of the half through holes and a bottom face of the main body, and many third conductive layers respectively filled in the penetrating holes. The hollow ceramic casing is fixed on the main body to form a receiving space. The LED chips is received in the receiving space. The package colloid is filled in the receiving space for covering the LED chips.
US07741647B2 Utilizing nanowire for different applications
One embodiment in accordance with the invention is an apparatus that can include a non-single crystal substrate and a nanowire grown from a surface of the non-single crystal substrate. Furthermore, the apparatus can also include an electrode coupled to the nanowire. It is noted that the nanowire can be electrically conductive and/or optically active.
US07741645B2 Three-dimensional integrated heterogeneous semiconductor structure
A first set of semiconductor devices is formed on a first semiconductor substrate comprising a first semiconductor material having a first melting point. A first via-level dielectric layer containing first contact vias is formed on the first semiconductor substrate. A second semiconductor substrate comprising a second semiconductor material having a second melting point lower than the first melting point is formed either by bonding or deposition. A second set of semiconductor devices is formed on the second semiconductor substrate. A second via-level dielectric layer, second contact vias contacting the second set of semiconductor devices, and inter-substrate vias electrically connecting the first contact vias are thereafter formed. A metal interconnect layer containing a metal interconnect structure is formed over the second via-level dielectric layer to electrically connect the first and second set of semiconductor devices through the second contact vias and the inter-substrate vias.
US07741642B2 Semiconductor device and manufacturing method thereof
The object is to provide a lightened semiconductor device and a manufacturing method thereof by pasting a layer to be peeled to various base materials.In the present invention, a layer to be peeled is formed on a substrate, then a seal substrate provided with an etching stopper film is pasted with a binding material on the layer to be peeled, followed by removing only the seal substrate by etching or polishing. The remaining etching stopper film is functioned as a blocking film. In addition, a magnet sheet may be pasted as a pasting member.
US07741638B2 Control layer for a nanoscale electronic switching device
A control layer for use in a junction of a nanoscale electronic switching device is disclosed. The control layer includes a material that is chemically compatible with a connecting layer and at least one electrode in the nanoscale switching device. The control layer is adapted to control at least one of electrochemical reaction paths, electrophysical reaction paths, and combinations thereof during operation of the device.
US07741637B2 ZnO-based semiconductor device
Provided is a ZnO-based semiconductor device capable of growing a flat ZnO-based semiconductor layer on an MgZnO substrate having a main surface on the lamination side oriented in a c-axis direction. ZnO-based semiconductor layers 2 to 6 are epitaxially grown on an MgxZn1-xO (0≦x<1) substrate 1 having a +C surface (0001), as a main surface, inclined at least in an m-axis direction. A p-electrode 8 is formed on the ZnO-based semiconductor layer 5, and an n-electrode 9 is formed on the underside of the MgxZn1-xO substrate 1. Thereby, steps regularly arranged in the m-axis direction can be formed on the surface of the MgxZn1-xO substrate 1, and a phenomenon called step bunching is prevented. Consequently, the flatness of a film of the semiconductor layers laminated on the substrate 1 can be improved.
US07741636B2 Programmable resistive RAM and manufacturing method
Integrated circuit nonvolatile memory uses programmable resistive elements. In some examples, conductive structures such as electrodes are prepared, and the programmable resistive elements are laid upon the prepared electrodes. This prevents contamination of the programmable resistive elements from previous fabrication steps.
US07741633B2 Ferroelectric oxide artificial lattice, method for fabricating the same and ferroelectric storage medium for ultrahigh density data storage device
The present invention is related to a ferroelectric storage medium for ultrahigh density data storage device and a method for fabricating the same. A supercell having high anisotropy is formed by controlling crystal structure and symmetry of unit structure (supercell) of artificial lattice by using an ordered alignment of predetermined ions having orientation of (perpendicular) deposition direction. Unit atomic layers of oxides having different polarization characteristic are deposited so that the supercell itself shows electric polarization having only two, upward and downward directions as one block of supercell having single-directional polarization. Oxide artificial lattices can be formed so as to have solely 180 degree domain structure, thus a single electric domain having improved anisotropic characteristic can be formed, thereby allowing capability of ultrahigh density data storage and long term data retention.
US07741630B2 Resistive memory element and method of fabrication
An integrated circuit including a memory cell and a method of manufacturing the integrated circuit are described. The memory cell includes a buried gate select transistor and a resistive memory element coupled to the buried gate select transistor. The resistive memory element stores information based on a resistivity of the resistive memory element.
US07741629B2 Apparatus for analysing surface properties with indirect illumination
An apparatus (1) for analysing surface properties, comprising a first radiation device (4) which emits radiation directly onto a surface (9) to be analyzed, a first illumination device (6, 7) for indirectly illuminating the surface (9) to be analyzed, a first radiation detector device (8) which receives at least part of the radiation thrown back from the surface (9) to be analyzed and outputs at least one signal which is characteristic of this part of the radiation. According to the invention, a radiation scattering device (10, 11) is provided which is at least partially illuminated by the first illumination device (6, 7) and which transmits scattered radiation onto the surface (9) to be analyzed.
US07741624B1 Single session interactive ultra-short duration super-high biological dose rate radiation therapy and radiosurgery
A medical accelerator system consisting of coplanar and non-coplanar beams, on line magnetic resonance anatomic and functional imaging and cone beam computed tomographic imaging for single session image guided all field simultaneous radiation therapy and radiosurgery is provided. This system enables single session simulation, field-shaping block making, treatment planning, dose calculations and treatment of tumors. The radiation exposure time to the tumor and the normal tissue is reduced to a few seconds to less than a minute. In filed intensity modulated radiation is rendered by combined divergent and pencil beam, multiple smaller fields within a larger field, selectively varying beam's energy, dose rate and beam weight. Since all the treatment fields are treated simultaneously the dose rate at the tumor site is the sum of each of the converging beam's dose rate at depth. This super-high biological dose rate impairs the lethal and sublethal damage repair.
US07741623B2 Patient positioning device
The invention relates to a patient-positioning device for positioning a patient in an irradiation position in a radiation therapy arrangement, in particular in a particle radiation therapy arrangement comprising a patient supporting module, which is provided with a patient supporting device for holding the patient in a body holder where the irradiation is to be carried out, wherein, said patient supporting device is mounted on a base unit in such a way that it is rotatable about an axis by means of a bearing, said base unit is provided with a coupling element, the inventive device is also provided with a positioning arm, which comprises several joints and a coupling point for coupling the coupling element and for freely positioning the patient in any predefined irradiation position by adjusting the angle of rotation of the patient supporting module.
US07741618B2 Enhanced portable digital lidar system
A system for detecting airborne agents. The system can include a laser source that provides laser pulses of at least two wavelengths, a transmitter that transmits the laser pulses, and a coupling mechanism configured to remotely couple the laser pulses between the laser source and the transmitter. The system can include a receiver receives both elastically backscattered signals from airborne agents and fluorescence signals from the airborne agents. The system can include a telescope both transmits a collimated laser beam of the laser pulse from the transmitter to a far field and receives the elastically backscattered signals and the fluorescence signals from the far field. The system can include a detection system having at least one of a backscatter optical detector that detects the elastically backscattered signals and one or more fluorescence optical detectors that detect the fluorescence signals in selected spectral band(s) from the airborne agents.
US07741614B2 Lithography system and lithography method using the same
The window-frame judgment unit judges that a section to be drawn has entered a window-frame area according to the main deflector data and the stage position information to output judgment signal. The main deflector calculator receives the main deflector data and calculates calculation data for driving a driving unit based on the main deflector data. The transfer controller detects output of the judgment signal and completion of drawing in the section under drawing to receive a transfer of the calculation data from the main deflector calculator and transfer the calculation data to the driving unit.
US07741612B2 Integrated neutron-gamma radiation detector with optical waveguide and neutron scintillating material
An integrated neutron-gamma radiation detector includes a gamma sensing element, a neutron sensing element comprising a neutron scintillating material at least partially surrounded by an optical waveguide material, and a photosensing element optically coupled to both the gamma sensing element and the neutron sensing element. A portion of the gamma sensing element is capable of being disposed within a central aperture of the neutron sensing element. In one aspect, the neutron sensing element comprises a plurality of cylindrical, concentric shells forming the central aperture for receiving the gamma sensing element. In another aspect, the neutron sensing element comprises a plurality of strands forming a multi-layered structure and forming the central aperture for receiving the gamma sensing element.
US07741610B2 CdTe/CdZnTe radiation imaging detector and high/biasing voltage means
A CdTe or CdZnTe radiation imaging detector and high voltage bias part for applying a high voltage to the continuous electrode to ensure stable performance of the detector. The high voltage bias part includes conductors of >30 um diameter and preferably selected from a group of materials that do not oxidize easily or oxidize less than aluminium.
US07741609B2 Adapting a high-performance pulse processor to an existing spectrometry system
A method of utilizing the output of a first pulse processor, such as processor designed for use with an SDD, to generate the input signal expected by the second pulse processor, such as an existing processor not designed for use with an SDD. In one embodiment, piled-up pulses which would not be detected as such by the second pulse processor are omitted from the generated input signal. The method generates an output (which then serves as the input signal for the second pulse processor) of the same general form as the ramp signal from a detector with a pulsed-reset preamplifier, but which does not have the same noise characteristics. In addition, the method may alter the timing between the reconstructed steps in the ramp to increase the maximum throughput of the second pulse processor beyond what is normally possible with a direct connection to the associated detector.
US07741606B2 Motor driven variable optical attenuator with IR sensor closed-loop control
Attenuators used to regulate optical signals are disclosed. According to one aspect of the present invention, an assembly including an IR source and an IR sensor is provided to sense blockage of optical signals transmitted between two collimators via a fixed common light blocker that is driven by a stepper motor. The movement of the light blocker is sensed by a sensing assembly including an IR source and IR sensor. By detecting the photocurrent from the IR sensor and a feedback circuit, the attenuation of the optical signals can be well controlled.
US07741605B2 Method and apparatus for detecting gas conveyed by drilling fluids
A method of detecting gas conveyed in a drilling fluid (M) returning from a well (26), which method comprises the steps of: (a) extracting gas from said drilling fluid (M); (b) transmitting infra-red radiation through said gas; and (c) detecting with a detector (50) infra-red red radiation that has passed through said gas and providing an output signal representative thereof; characterised by the step of: (d) examining the intensity of a portion of the infra-red spectrum within a range of approximately 3.1 μm and 3.6 μm to estimate whether or not said gas comprises any light or heavy hydrocarbons.
US07741604B2 Bolometer-type THz-wave detector
In a micro-bridge structure in which a temperature detecting portion 14 (diaphragm) including a bolometer thin film 7 is supported by a supporting portion 13 in a state floated from a circuit substrate 2, a reflective film 3 reflecting a THz wave is formed on the circuit substrate 2, an absorbing film 11 absorbing the THz wave is formed on the temperature detecting portion 14, and an optical resonance structure is formed by the reflective film 3 and the temperature detecting portion 14. And a gap between the reflective film 3 and the temperature detecting portion 14 is set approximately ¼ of a wavelength of an infrared ray on the basis of the wavelength of the infrared ray (in a range of approximately 1.5 to 2.5 μm, for example), and a sheet resistance of the temperature detecting portion 14 is set in a range in which an absorptance of the THz wave becomes a predetermined value or above on the basis of the THz wave (in a range of approximately 10 to 100 Ω/sq.). By this arrangement, the absorptance of the THz wave is drastically improved while using the structure and manufacturing technique of a bolometer-type infrared detector.
US07741603B2 Microcantilever infrared sensor array
A radiation sensor array that exhibits improved fill factor is disclosed. The radiation sensor array incorporates sensors having support arms that are nested in vertical fashion with the support arms of neighboring sensors. This vertically-nested structure enables the radiation-sensing portions of the sensors to be more closely-packed.
US07741602B2 Phase contrast electron microscope
A phase contrast electron microscope has an objective (8) with a back focal plane (10), a first diffraction lens (11), which images the back focal plane (10) of the objective (8) magnified into a diffraction intermediate image plane, a second diffraction lens (15) whose principal plane is mounted in the proximity of the diffraction intermediate image plane and a phase-shifting element (16) which is mounted in or in the proximity of the diffraction intermediate image plane. Also, a phase contrast electron microscope has an objective (8) having a back focal plane (10), a first diffraction lens (11), a first phase-shifting element and a second phase-shifting element which is mounted in or in the proximity of the diffraction intermediate image plane. The first diffraction lens (11) images the back focal plane of the objective magnified into a diffraction intermediate image plane and the first phase-shifting element is mounted in the back focal plane (10) of the objective (8). With the magnified imaging of the diffraction plane by the diffraction lens, the dimensional requirements imposed on the phase plate having the phase-shifting element are reduced.
US07741601B2 Testing apparatus using charged particles and device manufacturing method using the testing apparatus
A system for further enhancing speed, i.e. improving throughput in a SEM-type inspection apparatus is provided. An inspection apparatus for inspecting a surface of a substrate produces a crossover from electrons emitted from an electron beam source 25•1, then forms an image under a desired magnification in the direction of a sample W to produce a crossover. When the crossover is passed, electrons as noises are removed from the crossover with an aperture, an adjustment is made so that the crossover becomes a parallel electron beam to irradiate the substrate in a desired sectional form. The electron beam is produced such that the unevenness of illuminance is 10% or less. Electrons emitted from the sample W are detected by a detector 25•11.
US07741600B2 Apparatus and method for providing ions to a mass analyzer
A method and apparatus for directing ions from an ionization source to a mass analyzer is provided. The method includes producing ions from a sample in an ionization source. Some of the ions are transferred to a first region via a passageway that is in fluid communication with the ionization source. Next, some of the ions are sampled from the first region into a second region via an aperture that is defined thorough a partition element. The aperture is centered about a longitudinal axis that passes through an ion transfer element within the second region. An electric field is established for deflecting some of the ions that pass through the aperture of the partition element. In particular, the electric field is directed transverse to the longitudinal axis such that relatively more ions enter an input end of the ion transfer element compared to when the ions are not deflected.
US07741598B2 Optical interrogation system and method for using same
An optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which can be located within the wells of a microplate. In one embodiment, the optical interrogation system has a tunable laser, N-fiber launches, N-lenses and N-detectors that are set-up to interrogate N-biosensors. In another embodiment, the optical interrogation system has a tunable laser, N-fiber launches, N+1 lenses and N-detectors that are set-up to interrogate N-biosensors.
US07741593B2 Photoelectric conversion device and imaging system
A photoelectric conversion device comprises: a clipping unit including a MOS transistor which has a source connected to a signal line and a drain being connected to a power supply, and the clipping unit clipping an electric potential of the signal line to an electric potential corresponding to an electric potential of the source; a holding capacitance which has a first electrode and a second electrode, the first electrode being connected to a gate of the MOS transistor, and the holding capacitance holding at least a voltage transferred to the signal line while the charge-voltage converter has been reset; and a shift unit which shifts an electric potential of the second electrode in a direction such that the electric potential of the second electrode comes close to a level to be transferred to the signal line while the charge-voltage converter has been reset.
US07741590B2 Image sensor and image sensing apparatus comprising waveguide and multilayer wiring structure
An image sensor comprises a photoelectric conversion unit; a transfer transistor which has a gate electrode; a multilayer wiring structure which defines an aperture region above the photoelectric conversion unit; and a waveguide which guides light entering the aperture region to the light receiving surface, wherein the multilayer wiring structure includes a first wiring layer which is an uppermost wiring layer and defines two contour sides of the aperture region in a first direction, and a second wiring layer which is arranged between the gate electrode and the first wiring layer in a direction perpendicular to the light receiving surface, and defines two contour sides of the aperture region in a second direction, and wherein the gate electrode is arranged to overlap part of the light receiving surface and have a longitudinal direction along the first direction.
US07741587B2 Method for applying an isolation layer to a brazed end of a generator armature winding bar
A method of forming a brazed joint between an armature bar and a hydraulic header clip including: assembling free ends of hollow strands and of solid strands of the armature winding bar and positioning the assembly within the hydraulic header clip; interleaving a silver based braze alloy between the strands, wherein a portion of the braze alloy extends axially beyond the free ends of a plurality of the solid strands and the free ends of a plurality of the hollow strands extend axially beyond the braze material; positioning the assembly of the free ends, hydraulic header clip and the braze alloy in a braze chamber, such that the clip is seated in an induction heating coil of the chamber; heating the assembly to a first temperature below a solidus temperature of the braze alloy and within a 200 degrees Fahrenheit of the solidus temperature activating the induction heat coil to heat the clip; heating the assembly to a second temperature above the liquidus temperature of the braze alloy; pooling liquid braze alloy on ends of the armature bar, and cooling the assembly and clip thereby forming a braze isolation layer on the end of the armature bar.
US07741585B2 Integrated thermal unit having a shuttle with two-axis movement
An integrated thermal unit comprising a bake plate configured to heat a substrate supported on a surface of the bake plate; a chill plate configured to cool a substrate supported on a surface of the chill plate; and a substrate transfer shuttle configured to transfer substrates from the bake plate to the cool plate, wherein the substrate transfer shuttle has a temperature controlled substrate holding surface that is capable of cooling a substrate heated by the bake plate.
US07741583B2 Bake plate lid cleaner and cleaning method
A method and system for positioning a wafer on a bake plate in a processing module that includes lowering a bake plate cover assembly over the wafer during a baking process, raising the bake plate cover assembly after the baking process, removing the wafer, determining whether the bake plate cover assembly requires cleaning, then either processing another wafer if the cover assembly does not need cleaning or establishing a cleaning process for the bake plate cover assembly if the cover does need cleaning. Automated sensing of the state of the cover assembly may be employed, and cleaning process may be automatically performed in response to the cleaning need determination.
US07741582B2 Heater for automotive vehicle and method of forming same
There is disclosed a heater for an automotive vehicle or other article of manufacture. The heater typically includes a first conductive medium and a second conductive medium disposed upon a carrier. In a preferred embodiment, the first conductive medium includes a first section and a second section that are electrically connected by a second conductive medium. The second conductive medium preferably exhibits a positive thermal coefficient.
US07741574B2 Particle separation/purification system, diffuser and related methods
A separator and related separation methods are for intended use in separating particles having a selected charge from a particle mixture entrained in or carried by a fluid flow. The separator comprises a tubular, elongated body for receiving the fluid flow. At least one and preferably a pair of electrodes may be provided to create an electric field in at least a portion of the body through which the fluid flow passes, and at least one partition defines first and second channels for receiving the flow downstream of the portion of the body including the electric field. In one embodiment, the electrode is oriented such that a direction of gravity acting on particles having a selected charge passing through the electric field directs the selectively charged particles towards the first or second electrode. A system may incorporate the separator, along with a diffuser.
US07741573B2 Push switch
An operating body being made of a metal plate and being overlaid with polyamide resin layer, a side of the operating body having an operating part protruding from a front side of a switch case, and an other side having a driving part in an arm shape and a sliding guide in a frame shape surrounding the driving part, in which the driving part in the arm shape being compression pressed to be a thin plate, and the sliding guide being formed with an upper sliding contact in a hemisphere shape coming into contact with an undersurface of cover above the contact and a lower sliding contact formed long in back and forth direction coming into contact with a protective sheet under the contact.
US07741572B2 Switching device module
A switching device module comprising a frame (2), the switching device module being adapted to be connected to another switching device module for providing a modular switching device. The frame (2) of the switching device module is provided with one or more wire troughs (8), each of which is adapted to receive at least one wire of an auxiliary circuit of said modular switching device.
US07741568B2 Downward facing receptacle assembly for cable raceway
A cable raceway system includes a device bracket and a device cover for outfitting an elongate cable raceway with a downward facing electrical device. The raceway, configured for attachment to a wall surface, is of the type having an interior wireway. The device bracket is cooperative with the raceway for access to the wireway, and includes a device support for connecting an electrical device to the bracket, in a downward facing orientation with respect to the raceway. More particularly, when an electrical device is attached to the device support, an access face of the electrical device is oriented generally perpendicularly with respect to the wall surface. The cover cooperates with the bracket and raceway for covering the bracket, and has a faceplate portion complementary to the electrical device.
US07741566B2 Microelectronic substrates with thermally conductive pathways and methods of making same
This disclosure suggests microelectronic substrates with thermally conductive pathways. In one implementation, such a substrate includes a body and a thermally conductive member. The Body has a first surface that includes a microelectronic component mounting site, a second surface separated from the first surface by a thickness, and an opening extending through at least a portion of the thickness. The opening is outwardly open at one or both of the surfaces and has a first portion having a first transverse dimension and a second portion having a larger second transverse dimension. The thermally conductive member includes a first thickness, which is received in the first portion of the opening, and a second thickness, which is received in the second portion of the opening. A transverse dimension of the second thickness of the thermally conductive member is greater than the first transverse dimension of the opening.
US07741557B2 Apparatus for obtaining radiant energy
An apparatus for obtaining energy from a polychromatic radiant energy source has a light concentrator for concentrating and redirecting incident radiant energy, having an optical axis, and a spectral separator disposed along the optical axis, apart from the light concentrator and in the path of concentrated, redirected radiant energy. The spectral separator has a first planar surface treated to reflect a first spectral band of light toward a first focal region and to transmit a second spectral band and a second planar surface spaced apart from the first planar surface and oblique with respect to the first planar surface. The second planar surface is treated to reflect the second spectral band back through the first planar surface and toward a second focal region spaced apart from the first focal region. First and second light receivers are disposed nearest each respective focal region for receiving the first and second spectral bands.
US07741556B2 Methods and systems for interfacing an electric stringed musical instrument to an electronic device
Various embodiments of the present invention are directed to an electronic-device interface integrated into an electric stringed musical instrument. The electronic-device interface can be used for interconnecting an electric stringed musical instrument to an electronic device. In one embodiment of the present invention, an electronic-device interface includes a universal-serial-bus interface, a tip-ring-ring-sleeve output jack, and an enhanced electric-stringed-musical-instrument cable with a tip-ring-ring-sleeve connection at a first end and a universal-serial-bus connection at a second end. When an electric stringed musical instrument is equipped with an electronic-device interface, a user may insert the first end of the enhanced electric-stringed-musical-instrument cable into the tip-ring-ring-sleeve output jack and the second end of the enhanced electric-stringed-musical-instrument cable into a universal-serial-bus port for an electronic device. The user may then input music to the electronic device by playing music on the electric stringed musical instrument.
US07741554B2 Apparatus and method for automatically creating music piece data
A plurality of template data files are provided, each designating a structure and conditions of a music piece, and having a plurality of tracks, each track being assigned to a particular instrument group and defining a time progression structure of music to be performed by the assigned instrument group by setting performance sections at time positions to be performed by the assigned instrument group along the time progression of music. A plurality of component data files are provided, each representing a length of musical phrase that constitutes a predetermined tone progression pattern of a predetermined tone color for a performance by a particular instrument group. When conditions such as a tempo for a music piece to be created are given, a template data file that satisfies the given conditions is selected. Then, component data files are picked up according to the conditions designated by the selected template data file and the musical phrases are placed on the tracks in the template data file. Thus, data files of many and versatile music pieces are automatically created, satisfying the given conditions.
US07741550B2 Strainer system of snare drum and snare drum with the strainer system
A snare drum includes a strainer system which switches the position of a snare wire between an OFF position spaced from a lower drumhead and an ON position in contact with the lower drumhead. The strainer system includes a frame to which the snare wire is attached, and a pair of link mechanisms which are joined to the respective end portions of the frame and attach the respective end portions of the frame to a shell of the snare drum. After switching the position of the snare wire to the ON position, the position of the snare wire with respect to the lower drumhead is adjusted by operating an adjust screw of the second link mechanism.
US07741545B1 Maize variety X6K203
A novel maize variety designated X6K203 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety X6K203 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X6K203 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X6K203, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X6K203. This invention further relates to methods for producing maize varieties derived from maize variety X6K203 and to the maize varieties derived by the use of those methods.
US07741539B2 Transformed plant cell expressing five mammalian proteins involved in sialylation and a protein involved in galactosylation
The present invention relates to a method for producing heterologous glycosylated proteins in non-animal eukaryotic cells such as in transformed bryophyte, yeast, ciliate or algae cells. In particular, the method relates to a method for producing glycosylated proteins comprising animal glycosylation patterns—comprising sialic acid residues—, such as pharmaceutical proteins for use in mammals, e.g. humans, in bryophyte cells such as those of Physcomitrella patens, the genetic material required therefore, such as DNA and RNA, vectors, host cells, methods of introducing genetic material there into, and uses thereof. Furthermore, the present invention relates to novel polypeptides and proteins obtained by the method according to the invention. Moreover, the present invention provides a method of producing sialic acid or CMP-sialic acid in a transformed non-mammalian eukaryotic cell, tissue or organism.
US07741533B2 Grain quality through altered expression of seed proteins
The present invention is directed to compositions and methods for altering the levels of seed proteins in cereal grain. The invention is directed to the alteration of seed protein levels in plant grain, resulting in grain with increased digestibility/nutrient availability, improved amino acid composition/nutritional value, increased response to feed processing, improved silage quality, and increased efficiency of wet milling.
US07741531B2 Method for modifying gene expression of a phytopathogenic fungus
The present invention relates to a system for controlling the development of fungi during a phytopathogenic attack which enables the plant to express a construct for inhibiting the expression of a gene essential to the development or to the pathogenicity of the fungus. The technology used is based on the mechanism of RNA interference. The present invention provides methods for producing plants resistant to a phytopathogenic fungus, plant cells and plants resistant to a phytopathogenic fungus, and methods of identifying a gene essential to the development or to the pathogenicity of a phytopathogenic fungus.
US07741530B2 Multi-gene expression constructs containing modified inteins
Methods and constructs for the introduction of multiple genes into plants using a single transformation event are described. Constructs contain a single 5′ promoter operably linked to DNA encoding a modified intein splicing unit. The splicing unit is expressed as a polyprotein and consists of a first protein fused to an intein fused to a second protein. The splicing unit has been engineered to promote excision of all non-essential components in the polyprotein but prevent the ligation reactions normally associated with protein splicing. Additional genetic elements encoding inteins and additional proteins can be fused in frame to the 5′-terminus of the coding region for the second protein to form a construct for expression of more than two proteins. A single 3′ termination sequence, follows the last coding sequence. These methods and constructs are particularly useful for creating plants with stacked input traits and/or value added products.
US07741525B2 Blending processes and systems
Processes and systems are provided for monitoring and blending a first stream and a second stream to produce a third stream of desired compositional characteristics. The processes and systems are found to be particularly useful for the blending of two or more hydrocarbon streams to economically produce a targeted hydrocarbon product stream meeting prescribed compositional specifications. Specifically, the processes and systems are found to be especially useful to blend a propane containing stream, having a vapor pressure lower than the vapor pressure of a targeted vapor pressure for a propane product, with an ethane containing stream. The blending processes and systems allow for production of an “on-spec” propane product stream while at the same time maximizing the value of the ethane stream. The processes and systems may incorporate continuous real-time analysis and flow control of the various streams to effectuate precise control the blending processes.
US07741521B2 Inhibition of bid-induced cell-death using small organic molecules
Various phenylamine derivatives are described as well as the use of compounds to inhibit BID protein for controlling apoptotic cascade.
US07741520B2 Sulfonanilide analogs as selective aromatase modulators (SAMs)
Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloalkyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alkyl, aryl, alkylaryl, arylalkyl, and cycloalkyl; R3, with the base nitrogen, forms an amide or sulfonamide; R4 is selected from nitro, amine, amide, and benzamide; or a pharmaceutically acceptable salts thereof. Also provided are small molecule selective aromatase inhibitors having a molecular weight of less 500 g/mol. In some embodiments, the small molecule selective aromatase inhibitors described herein have a molecular weight of less than 450 g/mol. Also provided are methods for suppressing aromatase activity expression in cancer cells comprising the step of administering a pharmaceutically effective amount of a small molecule aromatase inhibitor to a subject in need of such treatment. In one embodiment, the cancer cells are breast cancer cells.
US07741516B2 Process to enrich a carboxylic acid composition
A process is provided for producing an enriched carboxylic acid compositions produced by contacting composition comprising a carboxylic acid with an enrichment feed in an enrichment zone to form an enriched carboxylic acid composition. This invention also relates to a process and the resulting compositions for removing catalyst from a carboxylic acid composition to produce a post catalyst removal composition.
US07741514B2 Catalyst comprising N-substituted cyclic imide compound and process for producing organic compound using the catalyst
A catalyst of the invention includes an imide compound having a N-substituted cyclic imide skeleton represented by following Formula (I): wherein R is a hydroxyl-protecting group. Preferred R is a hydrolyzable protecting group. R may be a group obtained from an acid by eliminating an OH group therefrom. Such acids include, for example, carboxylic acids, sulfonic acids, carbonic acid, carbamic acid, sulfuric acid, nitric acid, phosphoric acids and boric acids. The catalyst may include the imide compound and a metallic compound in combination. In the presence of the catalyst, (A) a compound capable of forming a radical is allowed to react with (B) a radical scavenging compound and thereby yields an addition or substitution reaction product of the compound (A) and the compound (B) or a derivative thereof. This catalyst can produce an organic compound with a high selectivity in a high yield as a result of, for example, an addition or substitution reaction under mild conditions.
US07741503B2 Mobile self-spreading biocides
A compound having the formula: Each R1 is C1-C3 alkyl group or fluoridated C1-C3 alkyl group. The value n is a positive integer. Each R2 is alkylene group or polyethylene glycol group. Y1 is hydrogen, quaternary ammonium-containing group, or phenol-containing group. Y2 is quaternary ammonium-containing group or phenol-containing group. The quaternary ammonium-containing group is non-aromatic and contains no more than one quaternary ammonium.
US07741501B2 Process for heterogeneously catalyzed hydrogenation
A process for carrying out heterogeneously catalyzed hydrogenation reactions in a fixed-bed reactor includes providing at least one main reactor containing a first amount of catalyst; providing a first auxiliary reactor and a second auxiliary reactor, each containing a second amount of catalyst, wherein the first amount of catalyst is relatively larger than the second amount of catalyst; passing a starting product of a fatty compound through the first auxiliary reactor and reacting the starting product with hydrogen in the presence of the catalyst; continuing the reaction through the at least one main reactor; and continuing the reaction through the second auxiliary reactor, wherein the first auxiliary reactor is reactivated. Another process provided includes a first and second main reactor, and a first and second auxiliary reactor, where relatively pure and impure starting products of a fatty compound are processed substantially continuously by cyclic switching of the reactors.
US07741494B2 Histone deacetylase inhibitors
Compounds, pharmaceutical compositions, kits and methods are provided for use with HDAC that comprise a compound selected from the group consisting of: wherein the substituents are as defined herein.
US07741492B2 Method for obtaining a pharmaceutically active compound (Irbesartan) and its synthesis intermediate
It is provided a method for obtaining Irbesartan polymorph A, with few synthesis steps, by coupling the intermediate of formula (II) with the compound of formula (III), neutralising one of its alkaline salts in an aqueous medium and recrystallising the crude product obtained. The utilisation of said method obviates protection and deprotection of the tetrazole ring and is therefore of considerable interest for obtaining Irbesartan on a large industrial scale. The invention also refers to the synthesis intermediate of formula (II).
US07741486B1 Water-soluble titanium alkoxide material
A water soluble, water stable, titanium alkoxide composition represented by the chemical formula (OC6H6N)2Ti(OC6H2(CH2N(CH3)2)3-2,4,6)2 with a theoretical molecular weight of 792.8 and an elemental composition of 63.6% C, 8.1% H, 14.1% N, 8.1% O and 6.0% Ti.
US07741484B2 Process for synthesis of phenoxy diaminopyrimidine derivatives
A method for preparing a compound of formula I the method comprising treating a compound of formula d with an iodination reagent, to form the compound of formula I, wherein R1, R2 and R3 are as defined herein.
US07741476B2 Cross-linking of low and high molecular weight polysaccharides preparation of injectable monophase hydrogels and polysaccharides and hydrogels thus obtained
A process for the crosslinking of at least one polymer selected from polysaccharides and derivatives thereof, which is carried out in an aqueous solvent by the action of an effective and non-excessive amount of at least one crosslinking agent, characterized in that it is carried out on a mixture containing at least one low-molecular weight polymer and at least one high-molecular weight polymer. A process for the preparation of an injectable monophase hydrogel of at least one crosslinked polymer selected from polysaccharides and derivatives thereof is also disclosed. Crosslinked polymers and injectable monophase hydrogels, respectively, are obtainable by each of said processes.
US07741474B2 Solubilising polysaccharides substituted with dydrophilic and hydrophobic groups
This invention relates to novel carbohydrate polymers with hydrophobic and hydrophilic side-groups suitable for solubilising, for example, hydrophobic drugs. The chain length of the carbohydrate polymeric backbone, and the type and number of the hydrophobic and hydrophilic side-groups are specifically chosen to improve the solubility properties of the carbohydrate polymers.
US07741470B2 siRNA targeting gremlin
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to CKSF1B1.
US07741469B2 Compositions for treating hearing loss and methods of use thereof
This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of genes encoding proteins involved in deafness caused by dominant negative mechanism of action by RNA interference (RNAi) using small nucleic acid molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid, short interfering RNA, double-stranded RNA (dsRNA), micro-RNA (mRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of genes involved in deafness caused by dominant negative mechanism of action.
US07741468B2 Human liver regeneration associated protein and the use thereof
This invention provides a novel human liver regeneration associated protein hLRTM4 and the polynucleotide which encodes the hLRTM4 protein. Furthermore, this invention provides a method of preparing and using hLRTM4 protein and its polynucleotides. hLRTM4 protein can be used to treat liver injury, and its antagonists (e.g. antisense nucleic acids and antibodies) can be used to treat hepatocellular carcinoma. This invention also provides the corresponding pharmaceutical compositions.
US07741462B2 Feline hemoplasma isolate
A newly identified hemoplasma agent, Candidatus Mycoplasma turicensis, is disclosed. Also disclosed are detection methods, screening methods and methods of diagnosis for the hemoplasma agent.
US07741460B2 Polynucleotides encoding a truncated ORF2 from Corynebacterium
The invention provides methods to increase the production of an amino acid from Corynebacterium species by way of the amplification of amino acid biosynthetic pathway genes in a host cell chromosome. Amplification may be by integration of one or more copies of a gene or genes into a host cell chromosome. One gene that may be incorporated is the gene ORF2, which encodes an unnamed hypothetical protein and which may be obtained from Corynebacterium glutamicum. The invention also provides novel isolated nucleic acid molecules for L-lysine biosynthetic pathway genes of Corynebacterium glutamicum.
US07741458B2 Spinocerebellar ataxia type 8 and methods of detection
The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
US07741457B2 6-modified bicyclic nucleic acid analogs
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
US07741455B2 Method for purifying FSH
The invention relates to a method for purifying recombinant human FSH or an FSH variant starting from crude FSH, comprising the following steps: 1) dye-affinity chromatography; 2) hydrophobic interaction chromatography; and 3) reverse phase chromatography.
US07741454B2 Biological low-molecular-weight derivatives
The crosslinking agents and condensing agents that have been employed in biological adhesives and in treating medical devices such as cardiac valves are non-natural compounds synthesized artificially. Thus, they are not metabolized in vivo and exhibit toxicity to living bodies. These compounds are thus used only in a restricted amount and for limited purposes in the clinical sites. The present invention provides a biological low-molecular-weight derivative obtained by modifying carboxyl groups of a biological low-molecular-weight compound with N-hydroxysuccinimide, N-hydroxysulfosuccinimide, or a derivative thereof and a crosslinked high-molecular-weight product obtained by crosslinking various high-molecular-weight compounds with this derivative.
US07741451B2 Antibodies that specifically bind hedgehog-derived polypeptides
The present invention provides two novel polypeptides, referred to as the “N” and “C” fragments of hedgehog, or N-terminal and C-terminal fragments, respectively, which are derived after specific cleavage at a G′CF site recognized by the autoproteolytic domain in the native protein. Also included are sterol-modified hedgehog polypeptides and functional fragments thereof. Methods of identifying compositions which affect hedgehog activity based on inhibition of cholesterol modification of hedgehog protein are described.
US07741448B2 Antibody having inhibitory effect on amyloid fibril formation
Disclosed is an antibody having a high inhibitory effect on amyloid fibril formation. An antibody is produced by using a liposome containing a GM1 ganglioside at a predetermined ratio as an immunogen. Thus, the sequences of four types of antibodies each having a high inhibitory effect on amyloid fibril formation can be provided.
US07741440B2 Apoptin-associating protein
The invention relates to the field of apoptosis. The invention provides novel therapies, for example, novel combinatorial therapies or novel therapeutic compounds that can work alone, sequentially to, or jointly with Apoptin, especially in those cases wherein p53 is completely or partially non-functional.
US07741435B2 Substance P-saporin (SP-SAP) conjugates and methods of use thereof
This invention provides a conjugate comprising Substance P, or an analog thereof, and a protein, such as Saporin, that inhibits protein synthesis.This invention provides a method of reducing the perception of pain by a subject comprising administering to the subject an effective amount of the pharmaceutical composition of the conjugate comprising Substance P, or an analog thereof, and a protein such as Saporin that inhibits protein synthesis, so as to reduce the perception of pain by the subject.This invention provides a method of selectively destroying NK-1R-expressing neuronal cells in a subject comprising administering to the subject an effective amount of the conjugate comprising Substance P, or an analog thereof, and a protein such as Saporin that inhibits protein synthesis, so as to selectively destroy NK-1R-expressing neuronal cells.Lastly, this invention provides a method for treating a NK-1R-associated disorder in a subject, which comprises administering to the subject an amount of the pharmaceutical composition comprising substance P, or an analog thereof, and a protein such as Saporin that inhibits protein synthesis, in an effective amount to treat the disorder associated with the NK-1R.
US07741431B2 Liposomes containing novel targeting and/or fusogenic peptides, preparations containing them and therapeutic use thereof
A novel targeting peptide from the C-terminal of endothelin and/or a novel fusogenic peptide from hemagglutinin are optionally conjugated to the carboxy group of 1,2-dioleoyl-sn-glycero-3-succinate and incorporated into liposomes for therapeutic treatment. The novel targeting peptide directs liposomes to lung cells, and, therefore, is useful for delivering liposomes encapsulating cholinesterase genes, particularly, the human serum butyryl cholinesterase (Hu BChE) gene, as a treatment against nerve agents. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims. 37 CFR §1.72(b).
US07741430B2 Polymerisation process
A process for the polymerisation of olefins is disclosed wherein at least part of a stream, preferably a catalytically active stream, withdrawn from a polymerisation reactor is passed through a fractionator so as to remove hydrogen and active fines.
US07741423B2 Highly oxygen permeable polymer
A polymer having a number average molecular weight (Mn) of from 10,000 to 5,000,000, as determined by gel permeation chromatography and reduced to polystyrene, and repeating units represented by the following formula (1): wherein R1 and R2 may be the same with or different from each other and are substituted or unsubstituted alkyl groups having 1 to 12 carbon atoms, a is a number of 0, 1, 2 or a mixture thereof, and b is a number of 0, 1, 2 or a mixture thereof.
US07741420B2 Polymer production at supercritical conditions
This invention relates to a process to polymerize olefins comprising contacting, under supercritical conditions, olefin monomers with a catalyst compound, an activator, optional comonomer, and optional hydrocarbon diluent or solvent.
US07741418B2 Process for producing polydienes
A process for preparing a polydiene, the process comprising the step of polymerizing conjugated diene monomer in the presence of a dihydrocarbyl ether, where said step of polymerizing employs a lanthanide-based catalyst system.
US07741416B2 Colloidal photonic crystals using colloidal nanoparticles and method for preparation thereof
The present invention relates to colloidal photonic crystals using colloidal nanoparticles and a method for the preparation thereof, wherein by adding a viscoelastic material into a solution containing the colloidal nanoparticles when preparing the colloidal photonic crystals, a uniform volume contraction occurs due to the elasticity of the viscoelastic material even when a nonuniform volume contraction occurs while drying a dispersion medium in the colloidal solution. Thus, it is possible to prepare 2 or 3 dimensional colloidal photonic crystals of large scale with no defects in less time.
US07741414B2 On the fly catalyst transitions
A process for transitioning between Ziegler Natta (Z/N) polymerization catalysts and Second Polymerization catalysts in a polymerization system which includes at least two polymerization reactors. During the transition, the Z/N catalyst is used in the “downstream” reactor, thereby providing a flow of polymer to finishing operations. This eliminates the need for lengthy shutdowns of finishing equipment and thereby improves the efficiency of the plant operations.
US07741405B2 Elastomeric composition
An elastomeric composition includes a reaction product of an isocyanate component and a resin component comprising a polyol and a polyetheramine in the presence of a first catalyst comprising a metal and a second catalyst comprising an amine. An elastomeric system and a method of making an elastomer are provided. The method includes providing the isocyanate component and the resin component, combining the resin component and the isocyanate component in the presence of the first and second catalysts to form an elastomeric composition, applying the elastomeric composition to a mold having a mold cavity, curing the elastomeric composition to form the elastomer, and demolding the elastomer from the mold cavity. An article including a first layer formed from the elastomeric composition emits less than 100 μg/g of volatile organic compounds over 0.5 hour at 90° C.
US07741401B2 Thickener blend composition and method for thickening aqueous systems
A thickener blend composition, and method for thickening aqueous systems, comprising an associative thickener wherein the same group that is attached to or within the backbone of the associative thickener is reversibly switched between being hydrophilic and hydrophobic in nature. When the group that is attached to or within the backbone is rendered hydrophilic, the aqueous thickener is pourable and readily incorporated into aqueous polymer compositions. When this group is rendered hydrophobic, the thickener performs its thickening function efficiently. Switching is readily accomplished by adjusting the pH of the associative thickener composition and the aqueous polymer composition being thickened.
US07741400B2 Water-absorbent resin, hydropolymer, process for producing them, and uses of them
The present invention provides a production process by which a water-absorbent resin of excellent quality can be obtained at a low cost by reasonable steps in aqueous solution polymerization. The process for producing a water-absorbent resin comprises the step of polymerizing an aqueous solution of water-absorbent resin-forming monomers including acrylic acid and/or its sodium salt as major components, wherein: (1) the aqueous solution has a monomer component concentration of not less than 45 weight %; (2) the polymerization is carried out while water is evaporated so that the ratio (concentration ratio) between a solid component concentration in a hydropolymer as formed by the polymerization and a solid component concentration in the aqueous monomer solution will not be less than 1.10; and (3) the solid component concentration in the hydropolymer as formed by the polymerization is not more than 80 weight %.
US07741398B2 Filled, low gloss, TPO compositions as substitutes for polycarbonate-abs blends
Compositions comprising (i) a crystalline, isotactic propylene homopolymer, (ii) an ethylene/α-olefin elastomeric impact modifier, and (iii) a reinforcing grade of filler, for example, talc. The crystalline isotactic propylene homopolymer has a flex modulus of greater than about 1930 MPa and a heat deflection temperature (HDT) of greater than about 100° C.; the ethylene/α-olefin interpolymer has a Tg of less than about −30° C., and a tan delta measured at 0.1 radians/s at 190° C. of less than about 2; and the filler has a HDT reinforcing efficiency of at least about 2. The composition has an HDT of greater than about 100° C. and a flex modulus of greater than about 1930 MPa.
US07741389B2 Resin composition and molded article
A resin composition with a high crystallization rate that contains a polyalkylene furan dicarboxylate resin and a porphyrin compound, and a molded article composed of the resin composition. The polyalkylene furan dicarboxylate resin is preferably a polybutylene furan dicarboxylate resin. The porphyrin compound is preferably hematoporphyrin dihydrochloride. The molded article is obtained by molding the resin composition.
US07741383B2 Versatile pigmented ink-jet inks with improved image quality
The present invention is drawn to versatile ink-jet inks, ink-jet ink sets, and methods of printing images with improved quality when printed on both glossy coated media and on plain paper. In accordance with these embodiments, an ink-jet ink formulated for printing on plain paper and glossy coated media can comprise a liquid vehicle including water, an organic solvent, and an organic amine; and a polymer-encapsulated, acid-sensitive pigment colorant dispersed the liquid vehicle.
US07741379B2 System and a method for a UV curable ink having infrared sensitivity
An ultraviolet (UV) curable ink having infrared (IR) sensitivity includes a UV light curable matrix, a UV photoinitiator, and an IR sensitive dye.
US07741377B2 Solid carbonaceous feed to liquid process
A process to prepare a paraffinic hydrocarbon from a solid carbonaceous feedstock, preferably coal by performing the following steps,(a) feeding an oxygen comprising gas and the carbonaceous feedstock to a burner positioned horizontal and firing into a reactor vessel,(b) performing a partial oxidation of the carbonaceous feedstock in said burner to obtain a stream of hot synthesis gas which flows upwardly relative to the burner and a liquid slag which flows downwardly relative to the burner,(c) cooling the hot synthesis gas by first cooling the gas to a temperature of between 500 and 900° C. by injecting a gaseous or liquid cooling medium into the synthesis gas and subsequently second cooling the gas in to below 500° C. by directly contacting with water, (d) separating solids from the cooled synthesis gas by means of a water scrubbing process step, (e) performing a water shift reaction on at least part of the scrubbed synthesis gas, (f) separating sulphur compounds, carbon dioxide and other possible impurities from the shifted gas to obtain a purified synthesis gas, and (g) performing a Fischer-Tropsch synthesis using the purified synthesis gas of step (f) to obtain a synthesis product comprising paraffinic hydrocarbons.
US07741376B2 Process for preparing dispersed ingredient having metal-oxygen bonds
A dispersed ingredient having metal-oxygen bonds which is obtained by hydrolyzing a metal alkoxide in an organic solvent in the absence of an acid, a base, and/or a dispersion stabilizer, either with 0.5 to less than 1 mol of water per mol of the metal alkoxide or at −20° C. or lower with 1.0 to less than 2.0 mol of water per mol of the metal alkoxide. In the organic solvent, the dispersed ingredient is stably dispersed without aggregating. Use of the dispersed ingredient enables a thin metal oxide film and a homogeneous organic/inorganic composite to be produced at a temperature as low as 200° C. or below.
US07741375B2 Polyketal polymers, and methods of making and using same
Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal polymers are biodegradable.
US07741373B1 Methods of use of fenofibric acid
Fenofibric acid formulations comprising 105 mg of fenofibric acid are described as well as methods of use thereof. Dosage forms include, for example, immediate-release dosage forms.
US07741370B2 Double salts of (−)-hydroxycitric acid and a process for preparing the same
This invention relates to new double salts of (−)-hydroxycitric acid with group II metals. Preferred double salts are calcium and magnesium double salts of hydroxycitric acid of the formula II. This invention also includes a process for the preparation of these double salts by the addition of one metal compound from group II to (−)-hydroxycitric acid solution followed by the addition of other metal compound solution from group II. These double salts are tasteless and are soluble in water. They are useful as dietary supplements and in beverages.
US07741362B2 Somatostatin receptor 1 and/or 4 selective agonists and antagonists
The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful.
US07741356B2 Compounds as opioid receptor modulators
The present invention is directed to novel opioid receptor modulators of Formula (I). The invention further relates to methods for preparing such compounds, pharmaceutical compositions containing them, and their use in the treatment of disorders that may be ameliorated or treated by the modulation of opioid receptors.
US07741354B2 Inhibitors of glutaminyl cyclase
The present invention relates to compounds of formula (I), combinations and uses thereof for disease therapy, wherein: R1 represents heteroaryl, -carbocyclyl-heteroaryl, -alkenylheteroaryl or -alkylheteroaryl; R2 represents alkyl, which may optionally be substituted by one or more groups selected from amino, halogen, hydroxyl, -alkoxy, -thioalkyl, —C(O)O-alkyl and —C(O)OH; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl, haloalkyl, amino, halogen, hydroxyl, alkoxy-, -thioalkyl, —C(O)O-alkyl and —C(O)OH; alkenyl; alkynyl; -alkyl-aryl; -alkyl-heteroaryl; -alkyl-heterocyclyl; -alkyl-carbocyclyl; -aryl-heteroaryl; -heteroaryl-aryl; -heteroaryl-heteroaryl; -aryl-aryl; -aryl (monocyclic or bicyclic); heteroaryl (monocyclic or bicyclic); heterocyclyl; or R2 together with R4 may form a carbocyclyl group optionally substituted by one or more alkyl groups; R3 represents alkyl, which may optionally be substituted by one or more groups selected from amino, halogen, hydroxyl, alkoxy-, -thioalkyl, —C(O)OH and —C(O)O-alkyl; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl, amino, halogen, haloalkyl, hydroxyl, -alkoxy, -thioalkyl, —C(O)OH and —C(O)O-alkyl; alkenyl; -alkyl-aryl; -alkyl(aryl)2, -alkyl(heteroaryl)2, -alkyl(aryl)(heteroaryl), -alkyl-heteroaryl; -alkyl-heterocyclyl which heterocyclyl group may optionally be substituted by one or more groups selected from alkyl, hydroxy and oxo ; -alkyl-carbocyclyl; -aryl-heteroaryl; -heteroaryl-aryl; -aryl-aryl; -aryl-O-aryl, -heteroaryl-heteroaryl; -aryl; heteroaryl; heterocyclyl; -aryl-alkyl-aryl; -aryl-O-alkyl-aryl; -alkyl-C(O)—NH-alkyl-aryl; -alkyl-C(O)—NH-alkyl-heteroaryl; -alkyl-C(O)—NH-alkyl-heterocyclyl; -alkyl-C(O)—(N-piperidinyl) or -alkyl-C(O)—(N-pyrrolidinyl) in which piperidinyl or pyrrolidinyl may optionally be fused to optionally substituted phenyl. R4 represents H or alkyl.
US07741352B2 KCNQ channel modulating compounds and their pharmaceutical use
This invention relates to novel compounds useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.
US07741346B2 Angiogenesis inhibitor
An object of the present invention is to find new pharmacological actions of urea compounds having structure represented by the general formula [1]. The urea compounds having the structure represented by the general formula [1] have excellent angiogenesis inhibitory actions. [wherein “A” is —(NR4)—, —(CR5R6)— or —O—, “B” is alkylene or alkenylene, R1, R2, R4, R5 and R6 are hydrogen, alkyl, alkenyl, adamantylalkyl or the like, R3 is aryl or an unsaturated heterocycle, and X is oxygen or sulfur].
US07741340B2 Hydroxy piperidine derivatives to treat gaucher disease
The present invention provides novel hydroxy piperidine (HP) derivatives having (i) a positive charge at the position corresponding to the anomeric position of a pyranose ring; (ii) a short, flexible linker emanating from the corresponding position of the ring oxygen in a pyranose; and (iii) a lipophilic moiety connected to the linker and pharmaceutically acceptable salts thereof. The linker can be absent if the lipophilic moiety corresponds to a hydrocarbon chain with a linear length of 6 or more carbons. The present invention further provides a method for treating individuals having Gaucher disease by administering the novel HP derivative as “active-site specific chaperones” for the mutant glucocerebrosidase associated with the disease.
US07741339B2 Fab I inhibitors
Compounds are disclosed which are Fab I inhibitors and are useful in the treatment bacterial infections.
US07741336B2 Pyrimidine derivatives for the treatment of abnormal cell growth
The present invention relates to a compound of the formula 1 wherein R1-R4 are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
US07741333B2 Quinazoline derivatives, their preparation, their use, and medicaments comprising them
The present invention relates to a quinazoline derivative having the general formula (A): in which R1, R2, X, Y and Z are indicated in the description and the claims, the use of the compounds of the general formula (A) for the treatment of various disorders, and the preparation of compounds of the general formula (A).
US07741331B2 A2B adenosine receptor antagonists
Disclosed are novel A2B adenosine receptor antagonists having the structure of Formula I or Formula II: The compounds are particularly useful for treating asthma, inflammatory gastrointestinal tract disorders, cardiovascular diseases, neurological disorders, and diseases related to undesirable angiogenesis.
US07741324B2 Imidazotriazines as protein kinase inhibitors
Compounds of the formula and pharmaceuticaly acceptable salts thereof, wherein Q1 and R1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of various diseases and conditions that respond to treatment by inhibition of tyrosine kinases.
US07741323B2 Indene derivatives and process for the preparation thereof
An indene derivative for selectively modulating the activities of peroxisome proliferator activated receptors (PPARs) having the following formula (I): wherein, R1 is C1-6 alkyl, C1-6 alkenyl, or C3-6 cycloalkyl, each of which is unsubstituted or substituted with one or more phenyl groups; R2 is H, CN, CO2Ra, CH2CO2Ra, CONRbRc, or phenyl; R3 is C1-6 alkyl, C3-6 cycloalkyl, naphthyl, phenyl, being each unsubstituted or substituted with one or more substituents selected from the group consisting of halogen, CN, NH2, NO2, ORa, phenyloxy, C1-6 alkyl, and C3-6 cycloalkyl; and R4, R5, R6, and R7 are each independently H, OH, OSO2CH3, O(CH2)mRe, CH2Rf, OCOCH2ORg, OCH2CH2ORg, OCH2CH═CHRg, or pyridine-2-yloxy, or R5 and R6 together form OCH2O.
US07741322B2 Isoquinolinone potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.
US07741321B2 Modulators of ATP-binding cassette transporters
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
US07741320B2 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compositions containing them
Compounds of formula (I): wherein: RCy represents an unsubstituted or substituted cycloalkyl group or cycloalkylalkyl group, R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen or halogen atom or a nitro group; a cyano group; a hydroxy group; an alkoxy group; an alkyl group; an unsubstituted or substituted amino group; a carboxy group; an alkoxycarbonyl group; an aryloxycarbonyl group; an unsubstituted or substituted aminocarbonyl group. Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator.
US07741314B2 2-Methylene-(20R,25S)-19,27-Dinor-(22E)-Vitamin D Analogs
This invention discloses 2-methylene-(20R,25S)-19,27-dinor-(22E)-vitamin D analogs, and specifically 2-methylene-(20R,25S)-19,27-dinor-(22E)-1α,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also has little, if any, calcemic activity and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.
US07741313B2 17,20(E)-dehydro vitamin D analogs and their uses
This invention discloses 17,20(E)-dehydro vitamin D analogs, and specifically 17(E)-1α,25-dihydroxy-17(20)-dehydro-2-methylene-19-nor-vitamin D3 and pharmaceutical uses therefor. This compound exhibits pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also has little, if any, calcemic activity and therefore may be used to treat autoimmune disorders and inflammatory diseases in humans as well as renal osteodystrophy and obesity.
US07741311B2 Composition and method for treating occlusive vascular diseases, nerve regeneration, and wound healing
A composition and a method of treating a subject with respect to a pathological condition comprised by the subject. The composition comprises a sulfated saccharide conjugated to a polymer. The method comprises administering to the subject a composition comprising a sulfated saccharide conjugated to a polymer or a sulfated saccharide. The sulfated saccharide has a molecular weight less than 5000 Dalton.
US07741310B2 Methods for stimulating nervous system regeneration and repair by regulating arginase I and polyamine synthesis
This invention relates to the novel identification of arginase as an enzymatic activity which can reverse inhibition of neuronal regeneration in the central and peripheral nervous system. Assays to monitor the effects of various agents on arginase expression and thus on neuronal regeneration and repair and to identify agents which will block or promote the inhibitory effects on neuronal outgrowth are provided. This invention also relates to compositions and methods using agents that can reverse the inhibitory effects of myelin on neural regeneration by affecting arginase activity or putrescine and derivative polyamine levels in a neuron. Methods for regulating and for promoting (or repressing) neuronal growth or regeneration in the nervous system, methods for treating injuries or damage to nervous tissue or neurons, and methods for treating neural degeneration associated with conditions, disorders or diseases, comprising the step of administering at least one of the compositions according to this invention, are provided.
US07741302B2 Transposase and method of gene modification
A transposase encoded by the Tol2 element; a polynucleotide encoding the same; a method of modifying the gene structure of a cell (preferably a vertebrate cell) by using the above protein; a method of modifying the function of a cell by modifying the gene structure thereof; and a cell having been modified in function by these methods. Also the structure of a cis element necessary in gene transfer is clarified and presented.
US07741301B2 Transposase and method of gene modification
A transposase encoded by the Tol2 element; a polynucleotide encoding the same; a method of modifying the gene structure of a cell (preferably a vertebrate cell) by using the above protein; a method of modifying the function of a cell by modifying the gene structure thereof; and a cell having been modified in function by these methods. Also the structure of a cis element necessary in gene transfer is clarified and presented.
US07741300B2 Methods of using nucleic acid vector-lipid complexes
This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, an infectious disease, or a condition associated with a deleterious activity of a self-antigen. Also disclosed are therapeutic compositions useful in such a method.
US07741296B2 Modulation of telomere length in telomerase positive cells and cancer therapy
Induction of telomere shortening, G2 arrest and apoptosis in telomerase positive cancer cells using acyclic nucleoside analogs has been disclosed. In addition, methods for impairment or prevention of tumorigenic telomerase positive cells from having a chance to grow into a tumor and methods for promoting tumor regression (decrease in size of an established tumor) using acyclic nucleoside analogs has been disclosed.
US07741292B2 Method of inhibiting the emigration of cells from the intravascular compartment into tissues
A method of inhibiting the emigration of cells from the intravascular compartment into tissues (or through any membrane limiting any body compartment from another) by confronting the cells with an agonist specific for receptors involved with migration of said cells via a receptor thereby making the cell unresponsive to further activation.
US07741290B2 Method of preventing progression of hypertension-induced heart failure with PKC peptides
Methods are described for slowing or inhibiting the progression of heart failure in a mammalian subject suffering from chronic hypertension. The methods involve administering an εPKC, β1PKC, or βIIPKC peptide inhibitor, examples of which are provided.
US07741288B2 Methods of screening of PP1-interacting polypeptides or proteins, peptides inhibiting PP1c binding to Bcl-2 proteins, Bcl-xL and Bcl-w, and uses thereof
The present invention relates to methods for identifying novel PP1-interacting polypeptides and proteins, compounds which are able to inhibit the binding of PP1c to certain factors naturally interacting with it, especially proteins of the Bcl-2 family (such as BCl-xL and Bcl-w), and pharmaceutical compositions comprising the same.
US07741286B2 Long lasting anti-angiogenic peptides
Modified anti-angiogenic peptides are disclosed. The modified peptides are capable of forming a peptidase stabilized anti-angiogenic peptide. The modified anti-angiogenic peptides, particularly modified kringle 5 peptides are capable of forming a conjugate with a blood protein. Conjugates are prepared from anti-angiogenic peptides, particularly kringle 5 peptides, by combining the peptide with a reactive functional group with a blood protein. The conjugates may be formed in vivo or ex vivo. The conjugates are administered to patients to provide an anti-angiogenic effect.
US07741284B2 BMP10 propeptides and related methods
In certain aspects, the present invention provides BMP10 propeptides for use in treating a variety of disorders including heart disorders and other disorders associated with unwanted activity of the mature BMP10 polypeptide. The present invention also provides methods of screening compounds that modulate activity of BMP10.
US07741283B2 Compositions and methods for inhibiting cell proliferation
Disclosed are compositions and methods useful in the regulation of cell proliferation. The invention provides TGF-β (transforming growth factor β) and IGFBP-3 (insulin like growth factor binding protein 3) as ligands that engage LRP (low density lipoprotein receptor-related protein), heretofore known as TβR-V (TGF-β receptor V) and IGFBP-3 receptor, to effect a change in the phosphorylation and activation status of IRS (insulin receptor substrate) proteins. Compositions comprising TGF-β or IGFBP-3 and LRP or IRS protein are useful in the inhibition of cell proliferation and in the treatment of various diseases associated with unregulated cell proliferation.
US07741279B2 Modified peptides and their uses
A modified pro-α chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-α chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecule may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.
US07741275B2 Agents and use thereof
The present invention provides agents for inhibiting the proliferation of cancer cells, wherein the agent inhibits the biological activity of hCAP18/LL-37. In a preferred embodiment, the agent alters the transcription, translation and/or binding properties of hCAP18/LL-37. Preferably, the agent is selected from the group consisting of short interfering RNA (siRNA) molecules, antisense oligonucleotides and compounds with binding affinity for hCAP18/LL-37. The invention further provides methods for inhibiting the proliferation of cancer cells in a patient, as well as methods and kits for diagnosing cancer.
US07741272B2 Artery- and vein-specific proteins and uses therefor
Arterial and venous endothelial cells are molecularly distinct from the earliest stages of angiogenesis. This distinction is revealed by expression on arterial cells of a transmembrane ligand, called EphrinB2 whose receptor EphB4 is expressed on venous cells. Targeted disruption of the EphrinB2 gene prevents the remodeling of veins from a capillary plexus into properly branched structures. Moreover, it also disrupts the remodeling of arteries, suggesting that reciprocal interactions between pre-specified arterial and venous endothelial cells are necessary for angiogenesis.
US07741270B2 Luminescent markers
The invention relates to luminescent proteins, nucleic acids encoding same, compositions and combinations comprising the proteins, and methods using the proteins, nucleic acids, compositions and combinations. In particular, a luminescent protein is provided comprising oncomodulin in which a salt bridge has been introduced to provide greater stability. The protein may be used as a luminescent marker in, for example, luminescent items, immunoassays, and fluorescent energy transfer assays.
US07741269B2 Exendins and exendin agonists for weight reduction and obesity
Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that affect satiety. The methods are useful for treating conditions or disorders, including obesity, Type II diabetes, eating disorders, and insulin-resistance syndrome. The methods are also useful for lowering the plasma glucose level, lowering the plasma lipid level, reducing the cardiac risk, reducing the appetite, and reducing the weight of subjects. Pharmaceutical compositions for use in the methods of the invention are also disclosed.
US07741267B2 Citronella and floral perfuming ingredient
The present invention relates to a perfuming ingredient of a compound of formula in the form of any one of its isomers or of a mixture thereof, and having a boiling point above 250° C., as measured at a pressure of 1013 mbar and its use in a method to confer, enhance, improve or modify the odor properties of a perfuming composition or perfumed article. The perfuming compositions and perfumed articles having the desirable odor characters are also part of this invention.
US07741260B2 Rinsing fluid for lithography
The invention provides a novel rinsing fluid which can convert an easily wettable resist pattern surface having a contact angle of 40° or below into one having a contact angle of 70° or above to inhibit pattern collapse effectively and thereby give high-quality products. The rinsing fluid consists of a solution containing at least one fluorine compound soluble in water or alcoholic solvents which is selected from among compounds represented by the general formula (I), those represented by the general formula (II), and those represented by the general formula: Rf′—COOH: wherein R1 and R2 are each optionally substituted C1-5 alkyl whose hydrogen atoms are partially or wholly replaced by fluorine, or R1 and R2 together with the SO2 groups to which they are bonded and the nitrogen atom may form a five- or six-membered ring; Rf is optionally substituted C1-5 alkyl whose hydrogen atoms are partially or wholly replaced by fluorine; m and n are each an integer of 2 or 3; and Rf′ is at least partially fluorinated alkyl having 8 to 20 carbon atoms.
US07741255B2 Aqueous compositions useful in filling and conveying of beverage bottles wherein the compositions comprise hardness ions and have improved compatibility with pet
The passage of a container along a conveyor is facilitated by applying to the container or conveyor aqueous compositions containing hardness ions. The compatibility of the aqueous compositions with PET bottles is improved when the ratio of hardness as CaCO3 to alkalinity as CaCO3 is greater than about 1 to 1.
US07741249B2 Geosynthetic composite for borehole strengthening
Disclosed is a composition comprising a chemical formulation useful for creating geosynthetic composites in-situ that includes a melamine-formaldehyde resin in a non-aqueous drilling fluid.
US07741247B2 Methods and compositions for sealing fractures, voids, and pores of subterranean rock formations
A region of a borehole with one or more openings to be sealed off, such as one or more fractures, voids, and or pores, may or may not be sealed off around a tubular string with a borehole seal such as a packer or plug. A carrying fluid may be utilized to transport a filtration material into the opening to create a bridge, which at least partially seals the opening, but still provides a flow path that permits fluid flow therethrough. A solid material and/or settable material may then utilize the fluid flow subsequently or be simultaneously spotted with or behind the filtration material to thereby form compositions which effectively seals off the flow path into the one or more openings.
US07741243B2 Production method of catalyst layer
Provided is a production method of a catalyst layer which is improved in catalyst activity and catalyst utilization efficiency. The method of producing a catalyst layer includes the steps of forming a first layer including a catalyst precursor on a substrate by a vapor phase process; forming cracks in the first layer; and reducing the first layer having the cracks formed therein.
US07741241B2 Hydroprocessing catalyst, method for the preparation thereof and use of the same
The invention relates to a hydrocarbon hydroconversion catalyst comprising a carrier based on refractory oxide, a metal of the group VIII, and a metal of the group VIB. Said catalyst is characterised in that it also comprises at least one organic compound selected from the alkene diols of formula (I) wherein R1 represents a C2-10 alkenylene group, preferably C2-4 alkenylene, a C6-18 arylene group, or a C7-18 alkylene-arylene group, and each R2 independently represents a hydrogen atom or a C1-18 alkyl group, a C1-18 alkenyl group, a C6-18 aryl group, a C3-8 cycloalkyl group, or a C7-20 alkylaryl or arylalkyl group, or the two groups R2 together form a divalent C2-18 group, the carbonated chain of the R2 groups containing or carrying at least one heteroatom selected from S, N and O. The invention also relates to a method for preparing one such catalyst, and to the use of said catalyst for hydrotreatment or hydroconversion.
US07741239B2 Methods of regeneration of SCR catalyst poisoned by phosphorous components in flue gas
A method of regeneration of a SCR catalyst for use in high temperature thermal processes such as in a power plant facility burning fossil fuels, bio-based fuels, or a combination thereof, wherein the catalyst is poisoned by phosphorous components in the flue gas and the catalyst is treated using a base, preferably an alkali metal hydroxide.
US07741232B2 Electron-emitting woven fabric and display device using same
An electron-emitting woven fabric according to the present invention is intended to provide an electron emission source that can be produced extremely easily, readily shaped to have a large area, and used for a wide variety of applications including a display device. The electron-emitting woven fabric according to the present invention is characterized in that first linear bodies 3 composed of a conductive layer 1 and an insulating layer 2 covering the conductive layer 1 and second linear bodies 4 of a conductive material are crossed. Another mode of the electron-emitting woven fabric according to the present invention is characterized in that a carbonaceous material is provided on a surface of each of crossed parts of the second linear bodies crossing the first linear bodies at lifted portions and/or sunk portions of the first linear bodies.
US07741225B2 Method for cleaning a solar cell surface opening made with a solar etch paste
A thin silicon solar cell having a back dielectric passivation and rear contact with local back surface field is described. Specifically, the solar cell may be fabricated from a crystalline silicon wafer having a thickness from 50 to 500 micrometers. A barrier layer and a dielectric layer are applied at least to the back surface of the silicon wafer to protect the silicon wafer from deformation when the rear contact is formed. At least one opening is made to the dielectric layer. An aluminum contact that provides a back surface field is formed in the opening and on the dielectric layer. The aluminum contact may be applied by screen printing an aluminum paste having from one to 12 atomic percent silicon and then applying a heat treatment at 750 degrees Celsius.
US07741224B2 Plasma treatment and repair processes for reducing sidewall damage in low-k dielectrics
A method of forming an interconnect structure for an integrated circuit, including the steps of providing a substrate and forming a dielectric stack on the substrate including an etch-stop layer, a low-k dielectric layer, and a hardmask layer. The method further includes the steps of patterning a photoresist masking layer on the dielectric stack to define a plurality of feature defining regions and plasma processing the substrate in a plasma-based reactor, The processing step includes etching a plurality of features into the hardmask layer and at least a portion of the low-k dielectric layer and performing a plasma treatment process in situ in the plasma-based reactor, where the plasma treatment process includes flowing at least one hydrocarbon into the reactor and generating a plasma, where a mass flow rate of the hydrocarbon is at least 0.1 sccm. The method also includes forming a metal conductor in the plurality of features.
US07741223B2 Semiconductor device with bulb type recess gate and method for fabricating the same
A method for fabricating a semiconductor device includes etching a substrate to form a first recess having a micro trench, etching the substrate disposed under the first recess to form a second recess having a profile substantially vertical and a width greater than a portion of the first recess where no micro trench is formed, etching the substrate disposed under the second recess to form a third recess having a profile substantially spherical, and forming a gate pattern over a resultant recess including the first to third recesses.
US07741216B2 Metal line of semiconductor device and method for forming the same
A metal line of a semiconductor device includes an insulation layer formed on a semiconductor substrate and having a metal line forming region. A diffusion barrier is formed on a surface of the metal line forming region of the insulation layer. The diffusion barrier has a multi-layered structure of a V layer, a VxNy layer and a VxNyOz layer. A metal layer is formed on the diffusion barrier to fill the metal line forming region of the insulation layer.
US07741207B2 Semiconductor device with multilayered metal pattern
A semiconductor device comprises a first insulating film formed on a semiconductor substrate, a first metal pattern formed on the first insulating film, a second insulating film formed on the first metal pattern, a second metal pattern formed on the second insulating film, and a third metal pattern formed in the second insulating film and connecting between the first metal pattern and the second metal pattern. The third metal pattern is a single continuous structure, and the principal orientation axes of crystals of a metal constituting the third metal pattern are parallel to the principal surface of the semiconductor substrate.
US07741199B2 Method for introducing impurities and apparatus for introducing impurities
A method for introducing impurities includes a step for forming an amorphous layer at a surface of a semiconductor substrate, and a step for forming a shallow impurity-introducing layer at the semiconductor substrate which has been made amorphous, and an apparatus used therefore. Particularly, the step for forming the amorphous layer is a step for irradiating plasma to the surface of the semiconductor substrate, and the step for forming the shallow impurity-introducing layer is a step for introducing impurities into the surface which has been made amorphous.
US07741197B1 Systems and methods for harvesting and reducing contamination in nanowires
The present invention is directed to methods to harvest, integrate and exploit nanomaterials, and particularly elongated nanowire materials. The invention provides methods for harvesting nanowires that include selectively etching a sacrificial layer placed on a nanowire growth substrate to remove nanowires. The invention also provides methods for integrating nanowires into electronic devices that include placing an outer surface of a cylinder in contact with a fluid suspension of nanowires and rolling the nanowire coated cylinder to deposit nanowires onto a surface. Methods are also provided to deposit nanowires using an ink-jet printer or an aperture to align nanowires. Additional aspects of the invention provide methods for preventing gate shorts in nanowire based transistors. Additional methods for harvesting and integrating nanowires are provided.
US07741194B2 Removable layer manufacturing method
A method (200) is described for an electronic assembly (30). An electronic die (24) with a sacrificial layer (28) on its back (27) and electrical contacts (26) on its front (25) is temporarily attached by its front (25) to a substrate (32). The back (27) is over-molded by a first material (34) extending over the substrate (32). The substrate (32) is removed leaving the die contacts (26) and the first material (33, 34) exposed. Interconnect layer(s) (44, 64) are provided over the first material (33, 34) and the die (24), electrically coupled to the contacts (26). Further components (66) can be coupled to the upper-most interconnects (64, 53). A second material (68) is over-molded over the components (66) and upper-most interconnects (64, 53). Thinning the first material (34) exposes the sacrificial layer (28) for removal. The die back (27) and vias (70) in the first material (34) extending to the first interconnect layer (43-2) laterally outside the die (24) are filled with a conductor (72, 72′, 73), providing single surface electrical and thermal contact (73-1, 73-2), separated by just the die thickness from heat generating regions of the die (24).
US07741190B2 Method of selective oxygen implantation to dielectrically isolate semiconductor devices using no extra masks
A method of fabricating integrated circuit structures utilizes selective oxygen implantation to dielectrically isolate semiconductor structures using no extra masks. Existing masks are utilized to introduce oxygen into bulk silicon with subsequent thermal oxide growth. Since the method uses bulk silicon, it is cheaper than silicon-on-insulator (SOI) techniques. It also results in bulk-silicon that is latch-up immune.
US07741189B2 Electrodes, inner layers, capacitors, electronic devices and methods of making thereof
A method of embedding thick-film fired-on-foil capacitors includes entirely covering the dielectric with an encapsulating electrode to avoid cracking in the dielectric due to shrinkage and temperature coefficient of expansion differences between the electrode and dielectric.
US07741188B2 Deep trench (DT) metal-insulator-metal (MIM) capacitor
A deep trench metal-insulator-metal (MIM) capacitor in an SOI-type substrate. In the deep trench, a layer of TiN, followed by a layer of high-k dielectric, followed by a second layer of TiN. The resulting capacitor is completely buried below the SOI layer, thereby allowing for subsequent structures to be placed over the deep trench.
US07741186B2 Creating increased mobility in a bipolar device
The mobility of charge carriers in a bipolar (BJT) device is increased by creating compressive strain in the device to increase mobility of electrons in the device, and creating tensile strain in the device to increase mobility of holes in the device. The compressive and tensile strain are created by applying a stress film adjacent an emitter structure of the device and atop a base film of the device. In this manner, the compressive and tensile strain are located in close proximity to an intrinsic portion of the device. A suitable material for the stress film is nitride. The emitter structure may be “T-shaped”, having a lateral portion atop an upright portion, a bottom of the upright portion forms a contact to the base film, and the lateral portion overhangs the base film.
US07741165B2 Polycrystalline SiGe Junctions for advanced devices
A structure and method of fabrication for MOSFET devices with a polycrystalline SiGe junction is disclosed. Ge is selectively grown on Si while Si is selectively grown on Ge. Alternating depositions of Ge and Si layers yield the SiGe junction. The deposited layers are doped, and subsequently the dopants outdiffused into the device body. A thin porous oxide layer between the polycrystalline Ge and Si layers enhances the isotropy of the SiGe junctions.
US07741163B2 Method of fabricating thin film transistor and organic electro-luminescent display device
A method of fabricating a thin film transistor is provided. A gate is formed on a substrate. A gate insulator is formed on the substrate to cover the gate. A source/drain layer is formed on the gate insulator, and a portion of the gate insulator above the gate is exposed by the source/drain layer. An isolated layer is formed on the source/drain layer and has an opening to expose a portion of the gate insulator and a portion of the source/drain layer above the gate. A channel layer is formed in the opening of the isolated layer to be electrically connected to the source/drain layer, and the channel layer is exposed by the opening.
US07741161B2 Method of making integrated circuit package with transparent encapsulant
A method for making an IC package with transparent encapsulant includes providing a leadframe, where the leadframe includes a first die pad and a second die pad, disposing a first die on the first die pad and a second die on the second die pad, forming a cavity on the leadframe, where the cavity includes the first die pad and the second die pad, injecting an encapsulant material into the cavity and cutting the injected encapsulant material and the leadframe to form a first IC package and a second IC package. The encapsulant material is transparent for visible wavelengths. The injection of the encapsulant material is performed at an encapsulant temperature ranging from 140° C. to 160° C.
US07741154B2 Integrated circuit package system with stacking module
An integrated circuit package system comprising: providing a module lead array; attaching a module integrated circuit adjacent the module lead array; attaching a module substrate over the module integrated circuit; and applying a module encapsulant over the module integrated circuit wherein the module lead array and the module substrate are partially exposed.
US07741152B2 Three-dimensional package and method of making the same
A method of making a three-dimensional package, including: (a) providing a wafer; (b) forming at least one blind hole; (c) forming an isolation layer; (d) forming a conductive layer; (e) forming a dry film; (f) filling the blind hole with a solder; (g) removing the dry film; (h) patterning the conductive layer; (i) removing a part of the lower surface of the wafer and the isolation layer, so as to expose the conductive layer; (j) stacking a plurality of the wafers, and performing a reflow process; and (k) cutting the stacked wafers, so as to form a plurality of three-dimensional packages. As such, the lower end of the conductive layer is inserted into the solder of the lower wafer, so as to enhance the joint between the conductive layer and the solder, and effectively reduce the overall height of the three-dimensional packages after joining.
US07741142B2 Method of fabricating a biosensor
The present invention provides a method of fabricating a biosensor. The method includes providing a substrate which has a surface coating. The surface coating is deformable and the substrate includes a layered structure which has at least two electrically conductive layers separated by at least one electrically insulating layer. The method also includes imprinting a structure into the surface coating. Further, the method includes etching at least a region of the imprinted structure and the substrate to remove at least a portion of the structure and the substrate. The structure is shaped so that the etching forms at least a portion of the biosensor in the substrate and exposes at least a portion of each electrically conductive layer to form electrodes of the biosensor.
US07741133B2 Resistance measurements of a helical coil
Test methods and components are disclosed for testing resistances of helical coils formed in magnetic recording heads. Helical coils in magnetic recording heads include a bottom coil structure, a top coil structure, and connecting structures that electrically connect the top and bottom coil structures. A test component is fabricated on the wafer along with the magnetic recording heads. The test component includes a bottom coil structure connected in series, and includes a top coil structure connected in series which is electrically disconnected from the bottom coil structure. Resistances of the top and bottom coil structures are measured in the test component. A total resistance of a helical coil is also measured. The resistance of the connecting structures in the helical coil may then be determined based on the resistance of the bottom coil structure, the resistance of the top coil structure, and the total resistance of the helical coil.
US07741130B2 Fluidic arrays and method of using
The present invention relates to fluidic systems and, in particular, fluidic arrays and methods for using them to promote interaction of materials. In one embodiment, the present invention is directed to a microfluidic system. The microfluidic system includes a first fluid path and a second fluid path segregated from the first fluid path by a first convection controller at a first contact region, wherein at least one of the first fluid path and the second fluid path has a cross-sectional dimension of less than about 1 millimeter. In another aspect, the present invention is directed to a method of promoting interaction. In another aspect, the invention relates to a device and method for performing titrations.
US07741129B2 Method for treating magnetic particles and biological analysis device using magnets
A method for treating magnetic particles present in a solution in a container by redispersion, rinsing or displacement, the particles having novel characteristics under the effect of a specific magnet and being associated or not with biological entities. The magnetic particles undergo at least one low-intensity magnetization where they are disposed in filaments oriented according to the north-south axis of the magnet; the magnetization source and/or container is/are displaced while the magnetic effect is maintained on the magnetic particles; the magnetization source and/or container is/are displaced or the magnetization is stopped, in order to suppress the magnetic field on the magnetic particles. Preferably, the invention can be used in the field of biology.
US07741128B2 Cooperative reporter systems, components, and methods for analyte detection
The present invention relates to methods and compositions to detect analytes in a sample using antibody molecules that are transformed into nanoscale “self-signaling” biosensors. It relates in particular to those methods and compositions that provide for single-step detection of target analytes without the need for labor-intensive steps necessary in conventional assays.
US07741126B2 Automated identification of carbohydrates in mass spectra
Disclosed is a computerized method for identifying peaks corresponding to glycans from a mass spectrum. At least one glycan spectrum is received from a mass spectrometer, with each glycan spectrum including peaks having a measured mass. Glycan identifications are automatically assigned to each of the peaks and these assignments are then reported.
US07741122B2 Determination of total base number in marine engine lubricants by elements
The present invention provides a method for determining the TBN of a used lubricating oil by measuring with a single device at least one element, such as sulfur, and correlating the measured amount to the oil's TBN. Preferably, a spectroscopic device is used to make the measurement.
US07741117B2 Bone mineralization protein expression systems, and methods of studying intracellular signaling pathways induced thereby
The present invention is directed to methods of switching a differentiation of a cell from a non-osteogenic lineage into an osteogenic lineage. The present invention is also directed to methods of generating a model system for assessing the intracellular signaling pathways of bone growth factors.
US07741116B2 Surgical device for skin therapy or testing
A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin, and provides structures and functions as in normal uninjured skin, such as barrier function, which is a definitive property of normal skin. The device contains cultured dermal and epidermal cells on a biocompatible, biodegradable reticulated matrix. All or part of the cells may be autologous, from the recipient of the cultured skin device, which advantageously eliminates concerns of tissue compatibility. The cells may also be modified genetically to provide one or more factors to facilitate healing of the engrafted skin replacement, such as an angiogenic factor to stimulate growth of blood vessels. The inventive device is easy to handle and manipulate for surgical transplant, can be made into large sheets to minimize the number of grafts required to cover a large surface area to be treated, and can be produced within the time frame to treat a burned individual requiring a skin graft.
US07741112B2 Vector mediated organelle transfection
The present invention provides compositions and methods for direct transfection of mitochondria and chloroplast DNA in living cells. More particularly, the present invention is based on the use of viral vectors that specifically bind to receptors uniquely found on the target organelle. In one embodiment, as shown in FIG. 1, a eukaryotic cell containing an organelle (1) that has been modified to express a viral receptor (2) on the organelle's surface is provided. A viral vector (6) comprising a desired recombinant DNA construct (3) is introduced into the cytosol of the cell, wherein the viral vector binds to its receptor and introduces the recombinant DNA into the interior of the organelle.
US07741107B2 Biological indicator
A biological indicator for monitoring the effectiveness of a sterilizing, disinfecting treatment or process. A compound or condition is disclosed which comprises a substrate having a surface layer containing functional groups thereon desirably free of silicon linking groups. The functional groups are desirably in the form of a monolayer of a uniformed distribution and of a selected quantity. Various types of microorganism indicators, such as spores and/or etiological agent indicators are covalently bonded to the surface layer functional groups through a crosslinking reagent and thus form a uniform number and distribution of the microorganism and/or etiological agent indicators. After being subjected to sterilization or other similar disinfecting treatments or processes, along with various articles such as instruments, the indicator can be cultivated to determine the effectiveness of the sterilization, disinfection, etc. treatment or process.
US07741105B2 Biomolecule chip and fabrication method thereof
Disclosed is a biomolecule chip and a fabrication method thereof. The biomolecule chip of the invention includes: a substrate; an insulating layer formed on the substrate; an adhesive layer formed on the insulating layer; a seed layer formed on the adhesive layer; an opening patterned at a predetermined location within the adhesive layer, the seed layer and the electroplating layer; and a biomolecule immobilized layer formed on the electroplating layer, the electroplating layer comprising a plasma-treated electroplating layer prior to the formation of the biomolecule immobilized layer. Accordingly, the immobilization of biomolecules onto the surface can be done more effectively by modifying the surface of the substrate in favor of biomolecules.
US07741102B2 Analyte detection and apparatus therefor
The present invention relates to sensitive SE(R)RS based methods for detecting analytes such as explosives and drugs, which may be present in a sample at extremely low levels. The methods may be generally carried out in situ employing novel chemistry which is compatible with flow-cell technology and with time-scales and concentrations required for rapid and informative screening of large numbers of samples. The present invention also relates to novel compounds e.g. synthons and apparatus for use with the methods disclosed.
US07741098B2 Production of eukaryotic proteins and nucleic acid molecules in C. elegans
Plasmid vectors for expression in Caenorhabditis elegans harbouring a heat inducible promoter nucleotide sequence, a synthetic intron nucleotide sequence optionally containing a Shine-Dalgarno sequence for efficient shuttling between C. elegans and E. coli, optionally a nucleotide sequence coding for a nuclear localisation signal or secretion signal, a nucleotide sequence coding for a recognizable tag, optionally a nucleotide sequence coding for a fluorescent protein, a nucleotide sequence coding for a protease cleavage site, a multiple cloning site containing a nucleotide sequence coding for an eukaryotic, such as human, protein or a nucleic acid molecule and a nucleotide sequence coding for termination of translation, are described. Methods of particularly large scale production of eukaryotic, such as human, proteins and nucleic acid molecules in nematodes are also described.
US07741097B2 Process for the preparation of amides
A novel biotechnological process for the preparation of nitriles, starting from amides, is described. Micro-organisms of the genus Amycolatopsis, Actinomadura or Rhodococcus are employed for this process.
US07741091B2 Methods of producing hyaluronic acid and chimeric and hybrid glycosaminoglycan polymers
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella multocida, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure.
US07741081B2 Process for producing L-arginine, L-ornithine or L-citrulline
The present invention provides a polypeptide which has: (i) an amino acid sequence wherein one or more amino acid residues are substituted in the region at positions 20 to 38 from the N terminus of the amino acid sequence shown in SEQ ID NO: 1; or (ii) an amino acid sequence wherein one or more amino acid residues are substituted in the region at positions 20 to 38 from the N terminus of the amino acid sequence shown in SEQ ID NO: 1 and one or more amino acid residues are deleted, substituted or added in the region at positions 1 to 19 or 39 to 294; and which has N-acetylglutamate kinase activity.
US07741079B2 Method of making a genetically modified mammalian cell
A method of making a genetically modified mammalian cell, the method including selecting a first codon of a parent polynucleotide that encodes a polypeptide for replacement with a synonymous codon, wherein the synonymous codon is selected on the basis that it exhibits a higher translational efficiency in a first type of mammalian cell than the first codon in a comparison of translational efficiencies of codons in cells of the first type, replacing the first codon with the synonymous codon to form a synthetic polynucleotide, and introducing the synthetic polynucleotide into a mammalian cell to produce the genetically modified mammalian cell.
US07741075B2 Pichia pastoris PIR1 secretion signal peptide for recombinant protein expression and Pichia pastoris PIR1 and PIR2 anchor domain peptides for recombinant surface display
The present invention is directed to recombinant nucleic acid constructs comprising nucleic acid sequences encoding a Pichia pastoris PIR secretion signal peptide for secretion or an anchor domain peptide for surface display of a heterologous polypeptide. The present invention is further directed to methods for obtaining a heterologous polypeptide secreted into the culture medium or displayed on the cell surface. The present invention is also directed to transformed cells containing the recombinant nucleic acid constructs.
US07741074B2 Polypeptides having endoglucanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US07741073B2 Plastidial targeting peptide
The invention relates to a non-cleavable, plastidial targeting polypeptide derived from a protein from the inner membrane of plant chloroplasts. Said peptide is particularly suitable for importing proteins of interest in plants.
US07741072B2 Polypeptide variants
A variant of a polypeptide comprising a human IgG Fc region is described, which variant comprises an amino acid substitution at one or more of amino acid positions 270, 322, 326, 327, 329, 331, 333 or 334 of the human IgG Fc region. Such variants display altered effector function. For example, C1q binding and/or complement dependent cytotoxicity (CDC) activity may be altered in the variant polypeptide. The application also discloses a variant of a parent polypeptide comprising a human IgG Fc region, which variant has a better binding affinity for human C1q than the parent polypeptide.
US07741069B2 Mesoporous material having dendritic skeleton containing immobilized glucose dehydrogenase
A porous material containing mesopores with immobilized glucose dehydrogenase is provided. The pore size is at least 10 nm.
US07741068B2 Methods for differentiation between cardiac and pulmonary causes of chronic dyspnea
The present invention relates to a method for differentiating in a subject suffering from chronic shortness of breath (dyspnea) between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease and (iv) dyspnea without cardiovascular or pulmonary causes. The method comprises the steps of determining an amount of a pulmonary surfactant protein in a sample of a subject, determining an amount of a natriuretic peptide in a sample of said subject, and differentiating between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease and (iv) chronic dyspnea without cardiovascular or pulmonary causes by comparing the amount determined in a) and the amount determined in b) with a reference amount for each. The present invention further provides a device and a kit for carrying out the inventive methods.
US07741062B2 Epitope-captured antibody display
Reagents and methods for detecting target proteins in a sample are provided. The reagents include a replicable genetic package, a protein displayed on an exterior surface of the package that is expressed from a heterologous nucleic acid borne by the package, and one or more antibodies complexed with the expressed protein and which have an open binding site for a target protein. Thus, a segment of the nucleic acid encodes for an epitope that is shared by the expressed polypeptide and the target protein. The reagents can be utilized individually or as part of a library or an array to bind target proteins within protein samples to form one or more complexes. By determining the sequence of the segment of the heterologous nucleic acid of a package within a complex, one can identify the target protein since the segment encodes for an epitope that is shared by the expressed and target proteins.
US07741061B2 Polysaccharide structure and sequence determination
The invention provides a method for the structural analysis of a saccharide, comprising: a) providing on a surface a plurality of essentially sequence- and/or site-specific binding agents; b) contacting said surface with a saccharide to be analyzed, or with a mixture comprising a plurality of fragments of said saccharide; c) washing or otherwise removing unbound saccharide or saccharide fragments; d) adding to the surface obtained in step c) an essentially sequence- and/or site-specific marker, or a mixture of essentially sequence- and/or site-specific markers; e) acquiring one or more images of the markers that are bound to said surface; and f) deriving information related to the identity of the saccharide being analyzed from said image.
US07741060B2 Methods and controls for monitoring assay quality and accuracy in parathyroid hormone measurement
The present invention relates to the use of control compositions and kits comprising such to evaluate and monitor the consistency of assays utilized to determine parathyroid hormone levels.
US07741058B2 Methods and compositions for detecting spermatozoa or semen in a sample
The present invention concerns compositions and methods for evaluating fertility in humans and animals. The invention may also be used to identify reproductive cancers such as testicular cancer. In various embodiments of the invention, an Sptrx-3 enzyme is used as a fertility marker. Sptrx-3 may be detected in accordance with the invention in vitro or in vivo.
US07741055B2 Prostatic growth factor
The present invention relates to human PGF polypeptides and DNA (RNA) encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques, and antibodies and antagonist/inhibitors against such polypeptides. Also provided are methods of using such polypeptides therapeutically for treating prostate cancer, to promote tissue regeneration and to facilitate wound healing. Also provided is a diagnostic assay to detect prostate cancer and benign prostatic hyperplasia.
US07741050B2 Identification of agonistic autoantibodies
The invention relates to a method for detecting disease-associated autoantibodies, which recognize extracellular structures of G protein-coupled receptors, and to the use of peptides, which comprise these loops or fragments thereof, for treating autoimmune diseases.
US07741045B2 Sequential analysis of biological samples
Methods for probing multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample containing multiple targets, binding at least one fluorescent probe to one or more target present in the sample, and binding at least at least one control probe to one or more target present in the sample. The methods include the steps of observing a signal from the fluorescent probe and a control signal from the control probe and applying to the sample a basic solution containing an oxidizing agent that selectively inactivates the fluorescent probe and not the control probe. The methods further include the steps of binding at least one fluorescent probe to one or more target present in the sample and observing a signal from the fluorescent probe. The methods disclosed herein also provide for multiple iterations of binding, observing, and oxidizing for deriving information about multiple targets in a single sample. An associated kit is also provided.
US07741038B2 Methods and compositions for evaluating graft survival in a solid organ transplant recipient
Methods are provided for evaluating a subject for graft survival, e.g., in terms of predicting graft survival, identifying the presence of a deleterious graft condition, such as CAN and DT, identifying the severity and class of acute rejection, etc, in a subject are provided. In practicing the subject methods, the expression of at least one gene in a sample from the subject, e.g., a blood or biopsy sample, is assayed, e.g., at the nucleic acid and/or protein level, to evaluate the subject. Also provided are compositions, systems and kits that find use in practicing the subject methods. The methods and compositions find use in a variety of applications.
US07741037B2 Method for pheromone discovery in insects
The present invention is directed generally to a method of identifying an insect pheromone. Initially, a candidate insect pheromone-binding protein is obtained and sequenced. Specific proteins may then be selected by observing the pattern of pheromone-binding protein expression in the insect stage, phase or caste; and/or in the antenna and other sensilla by, for example, in situ hybridization; and/or by comparison with sequence of known pheromone binding proteins. A composition of one or more pheromones may then be contacted with the pheromone-binding protein. Any pheromones bound to the protein may then be eluted and analyzed.
US07741036B2 Method for rapid detection and identification of bioagents
Method for detecting and identifying unknown bioagents, including bacteria, viruses and the like, by a combination of nucleic acid amplification and molecular weight determination using primers which hybridize to conserved sequence regions of nucleic acids derived from a bioagent and which bracket variable sequence regions that uniquely identify the bioagent. The result is a “base composition signature” (BCS) which is then matched against a database of base composition signatures, by which the bioagent is identified.
US07741035B2 Use of gene expression profiling to predict survival in cancer patient
Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to over-expression of genes such as ASPM, OPN3 and CKS1B which are located in chromosome 1q. Given the frequent amplification of 1q in many cancers, it is possible that these genes can be used as powerful prognostic markers and therapeutic targets for multiple myeloma and other cancer.
US07741033B2 Electrocatalytic nucleic acid hybridization detection
The detection of specific nucleic acid sequences using electrochemical readout would permit the rapid and inexpensive detection and identification of bacterial pathogens and the analysis of human genes. A new assay developed for this purpose is described that harnesses an electrocatalytic process to monitor nucleic acid hybridization. Furthermore, the new assay when used on nanoscale electrodes, provides ultrasensitive detection of nucleic acids.
US07741032B2 Genotyping assay to predict gamma glutamyl hydrolase (GGH) activity
Single nucleotide polymorphisms (SNPs) in the gene encoding gamma glutamyl hydrolase (GGH) associated with reduced GGH activity are disclosed. The primary SNP is a change from a cytosine to a thymine at a position corresponding to nucleotide 511 of Genbank sequence accession no. NM 003878. Methods and kits for detecting these SNPs are provided, along with primers useful in detecting these SNP and for amplifying portions of the GGH gene containing these SNPs.
US07741031B2 Optically decodable microcarries, arrays and methods
A coding scheme for microcarriers suitable for use in distributed arrays includes labeling the carriers with quenched signaling hairpin molecules with any one of three to eight distinguishable fluorophores wherein the hairpins are of at least two types, most preferably three types, that open and fluoresce differentially as a chemical or physical condition, for example temperature, is changed. Mixtures of microcarriers having immobilized capture probes can be decoded by measuring fluorescence from said fluorophores under conditions under which only one type of hairpin is open, under which two types of hairpin are open, and so on. Mixtures of coded microcarriers with capture probes are used in assays for nucleic acids utilizing microarray methods.
US07741028B2 Methods of identifying genetic markers in the human cystic fibrosis transmembrane conductance regulator (CFTR) gene
The present invention relates to the field of genetic screening. More specifically, the described embodiments concern methods to screen multiple samples, in a single assay, for the presence or absence of mutations or polymorphisms in a plurality of genes. Approaches to screen for the presence or absence of mutations that are associated with cystic fibrosis and approaches to design primers that generate extension products that facilitate the resolution of multiple extension products in a single lane of a gel or in a single run on a column are also provided.
US07741027B2 Amplification of HIV-1 sequences for detection of sequences associated with drug-resistance mutations
Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
US07741026B2 Circovirus sequences associated with piglet weight loss disease (PWD)
The genome sequences and the nucleotide sequences coding for the PWD circovirus polypeptides, such as the circovirus structural and non-structural polypeptides, vectors including the sequences, and cells and animals transformed by the vectors are provided. Methods for detecting the nucleic acids or polypeptides, and kits for diagnosing infection by a PWD circovirus, also are provided. Method for selecting compounds capable of modulating the viral infection are further provided. Pharmaceutical, including vaccines, compositions for preventing and/or treating viral infections caused by PWD circovirus and the use of vectors for preventing and/or treating diseases also are provided.
US07741022B2 Protein inhibitor of Ran activity and methods of use thereof
The invention provides a method of inhibiting Ran protein activity in at least one eukaryotic cell or cell-free extract, the method comprising exposing an amino acid sequence comprising at least a portion of EMCV or TMEV leader protein, wherein the amino acid sequence comprises SEQ. ID NO: 14 or SEQ. ID NO: 15, to at least one cell in an amount effective to inhibit Ran activity in the targeted cell and evaluating Ran protein activity in the cell.
US07741021B2 Protein O-sulfonation
Post-translational O-sulfonation of a serine or threonine residue of proteins is detected, optionally comparatively, wherein the detected O-sulfonation is detected under a first physiological condition, and is compared with a control O-sulfonation detected under a second physiological condition, and a difference between the detected and control O-sulfonations indicates a difference between the first and second physiological conditions.Predetermined changes in physiological conditions are used to infer specific changes in O-sulfonation. Proteins are modified by introducing a predetermined change in O-sulfonation at a serine or threonine residue of the protein, and optionally, detecting a resultant change in O-sulfonation. These methods include introducing or increasing O-sulfonation, eliminating or reducing O-sulfonation; and derivatizing or substituting O-sulfonation.
US07741019B2 Detection of ovarian cancer
A method for the diagnosis, prognosis, and monitoring of ovarian cancer in a subject by detecting hK10 in a sample from the subject, preferably a serum sample or tumor tissue extract. hK10 may be measured using a reagent that detects or binds to hK10 preferably antibodies specifically reactive with hK10 or a part thereof. Imaging methods for tumors associated with hK10 are also described using an agent that binds to hK10 which had a label for imaging the tumor.
US07741018B2 Advantageous vitrifiable cryoprotectant mixtures
Disclosed herein are aqueous carrier solutions for cryoprotectants that are useful for a variety of cryoprotectant solutions for use with cells, tissues, and whole organs, said aqueous carrier solutions permitting antinucleators to be fully effective in vitrification solutions, thereby allowing vitrification solutions to attain extreme effectiveness, and compatible vitrification solution compositions for use with these carrier solutions. The carrier solutions comprise lactose, mannitol or trehalose, and glucose in combination with other beneficial ingredients.
US07741016B2 Method for fabricating semiconductor device and exposure mask
The method for fabricating the semiconductor device includes the step of forming a photoresist film 84 over a substrate 10, the step of exposing interconnection patterns to the photoresist film 84, the step of exposing to the photoresist film 84 hole patterns of a plurality of holes positioned at ends or bent portions of the interconnection patterns where holes to be connected to the interconnection patterns are to be formed, and the step of developing the photoresist film 84 with the interconnection patterns and the holes patterns exposed to. Thus, the insufficient exposure energy at the ends or the bent portions of the patterns due to optical proximity effect is compensated to prevent the shortening at the pattern ends or the rounding at the pattern bent portions. The contacts with the contact plugs connected to the pattern ends or the pattern bent portions can be ensured.
US07741013B2 Process for thick film circuit patterning
A process for patterning thick film electrically functional patterns using a photosensitive polymer layer. A tacky photosensitive layer is applied onto a substrate surface. The photosensitive layer is imaged with a pattern using actinic radiation, the exposed areas of the photosensitive layer become hardened and non-tacky. A subsequent application of a thick film composition sheet will cause the thick film to adhere to the remaining tacky areas. Upon peeling the sheet, a thick film print pattern will be produced. This step is followed by a processing profile prescribed by the thick film composition used which results in a pattern having electrically functional properties. The invention also extends to a process wherein a thick film composition is recovered from a used sheet.
US07741012B1 Method for removal of immersion lithography medium in immersion lithography processes
A process for fabricating a semiconductor device, including applying an immersion lithography medium to a surface of a semiconductor wafer; exposing a material on the surface of the semiconductor wafer to electromagnetic radiation having a selected wavelength; and applying supercritical carbon dioxide to the semiconductor wafer to remove the immersion lithography medium from the surface of the semiconductor wafer. In one embodiment, the process includes recovery of the immersion lithography medium.
US07741007B2 Chemicallly amplified resist composition
The present invention provides a chemically amplified resist composition comprising: (A) a salt represented by the formula (1) wherein R21, Q1, Q2, and A+ defined in the specification; (B) a salt represented by the formula (II): wherein R22, Q3, Q4, and A′+ are defined in the specification; and (C) a resin which contains a structural unit having a structural unit having an acid-labile group and which itself is insoluble or poorly soluble in an aqueous alkali solution but becomes soluble in an aqueous alkali solution by the action of an acid.
US07741004B2 Method of forming pattern by utilizing coatable inorganic material
A coatable inorganic material is provided, which is suitable for being coated on a substrate in the form of sol-gel solution and then being directly written with thermochemical mode by using a laser beam. The coatable inorganic material is an oxide, in which the chemical element constitution is more than one element selected from Te, Al, Zr, and Ti.
US07741003B2 Photoresist transfer pads
A resist transfer pad and method of use are described for forming a uniform photoresist on the surface of a workpiece such as a slider. The resist transfer pad includes a layer of cured polydimethylsiloxane (PDMS) on a cushioning layer, e.g. silicone rubber, and an optional stiffening layer. The sliders are preferably mounted on a carrier or pallet. In one preferred embodiment the loaded resist transfer pads are applied to the slider surface by roll lamination where the loaded resist transfer pad is transported by a roller system using a cover-tape and pressed against the slider surface. Subsequently the cover-tape and the resist transfer pad are lifted off and the photoresist remains on the transducer. An alternative embodiment uses a vacuum, piston laminator to press the loaded resist transfer pad onto the surface of the transducer.
US07740998B2 Positively chargeable developer
A positively chargeable developer is provided which is capable of providing stable image quality without causing any image defect even in long-term use. The developer includes at least positively chargeable toner particles each containing at least a binder resin and magnetic iron oxide, silica and an inorganic fine powder. A unconfined yield strength at a major consolidation stress of 5 kPa of the developer is in the range of 0.1 to 2.5 kPa, and a unconfined yield strength at a major consolidation stress of 20 kPa of the developer is in the range of 2.5 to 5.5 kPa.
US07740997B2 Photoreceptor including multi-block polymeric charge transport material at least partially embedded within a carbon nanotube material
An electrophotographic imaging member includes a substrate, a photogenerating layer, and an optional overcoating layer, where the photogenerating layer includes a multi-block polymeric charge transport material at least partially embedded within a carbon nanotube material.
US07740996B2 Photosensitive resin composition and color filter
A positive photosensitive resin composition exhibiting excellent heat resistance is provided, which comprises an alkali-soluble resin component (A) and a photosensitizer (B), the component (A) including a resin component (A1) having a structural unit (a1) represented by general formula (a1) shown below: wherein R0 represents a hydrogen atom or a methyl group; R1 represents a single bond or an alkylene group of 1 to 5 carbon atoms; R2 represents an alkyl group of 1 to 5 carbon atoms; and a represents an integer of 1 to 5, and b represents 0 or an integer of 1 to 4, with the proviso that the sum of a and b is 5 or less, and when two or more R2 are present, R2 may be the same or different.
US07740993B2 Mask for sequential lateral solidification (SLS) process and a method for crystallizing amorphous silicon by using the same
A mask for sequential lateral solidification (SLS) processes including at least one first window, one second window, one third window, and one fourth window is provided. Each window has a length extending longitude on the mask. The second window is aligned to the first window. The width of the first window is greater than that of the second window. The fourth window is aligned to the third window. The width of the third window is greater than that of the fourth window.
US07740989B2 Micro fuel cell with an electrolytic membrane reinforced by an anchoring element and method for production of a micro fuel cell
A micro fuel cell comprises at least a substrate provided with front and rear faces. The front face of the substrate supports a successive stacking of a first electrode, a substantially flat electrolytic membrane and a second electrode. The electrolytic membrane comprises at least one anchoring element salient substantially perpendicularly to a main plane of said membrane. The anchoring element is arranged in a complementary part of an anchoring recess formed in the substrate. The substrate can also comprise a plurality of microchannels, substantially perpendicular to the main plane of the membrane. The anchoring recess can then be formed by one of the microchannels whereas the other microchannels enable supply of the first electrode with reactive fluid. Such a micro fuel cell is able to operate when a pressure difference exists between the two sides of the stacking.
US07740988B2 Fuel cell plate structure having baffles in wet seal area
An assembly having fuel cell plate structure adapted for use in a fuel cell in which gas flow channels are arranged to carry process gas adjacent the active and wet seal areas of the fuel cell, the plate structure having one or more baffles arranged such that when the plate structure is in the fuel cell the baffles of the plate structure cause the process gas flowing adjacent the wet seal areas to be directed away from the wet seal areas and toward the active areas of the cell.
US07740984B2 Alkaline cells having high capacity
Aspects of the present invention provide a high capacity electrochemical cell having an anode, a cathode, and a separator disposed between the anode and cathode. The cathode includes a mixture having a first component, a second component and a third component. The first component includes a first element, the second component includes a second element, and the third component includes the first element and the second element. The mixture can, for instance, be a mixed metal oxide. The separator is configured to provide suitable ionic transport between the anode and the cathode.
US07740981B2 Assembled battery including insulating support plate connected to a terminal surface
An assembled battery is equipped with an insulating support plate supporting bus bars, omits the bolting operation and can simplify the operation of electrically connecting the bus bars to electrode terminals. The assembled battery includes a plurality of battery modules having output terminals. An insulating bus bar plate (support plate) supports conductive bus bars that are electrically connected to the terminal surfaces. A guide movably guides the bus bar plate between a first position in which the bus bars are electrically connected to the terminal surfaces and a second position in which the bus bars are separated from the terminal surfaces. A lock supports the bus bar plate in the first position and maintains the bus bars in a state that is forcibly connected to the terminals surfaces.
US07740977B2 Vanadium redox battery incorporating multiple electrolyte reservoirs
A vanadium redox battery energy storage system (“VRB-ESS”) capable of modularly incorporating additional electrolyte reservoirs to increase energy capacity while allowing for efficient low-volume operation is disclosed. The VRB-ESS of the present invention may efficiently operate using a first volume of electrolyte solution, while maintaining a second volume of electrolyte solution to be made available to the VRB-ESS as additional energy storage capacity is required. Additionally, a cap mechanism to allow the VRB-ESS of the present invention to employ an industry standard IBC container as a secondary electrolyte reservoir is disclosed.
US07740974B2 Formic acid fuel cells and catalysts
An exemplary fuel cell of the invention includes a formic acid fuel solution in communication with an anode (12, 134), an oxidizer in communication with a cathode (16, 135) electrically linked to the anode, and an anode catalyst that includes Pd. An exemplary formic acid fuel cell membrane electrode assembly (130) includes a proton-conducting membrane (131) having opposing first (132) and second surfaces (133), a cathode catalyst on the second membrane surface, and an anode catalyst including Pd on the first surface.
US07740972B2 Fuel cell unit and composite block of fuel cells
In order to provide a fuel cell unit, comprising a housing which limits at least one gas chamber and has a gas opening in a first housing wall and a gas opening in a second housing wall located opposite the first housing wall, the housing of which has an adequate deformation stability in relation to the sealing surface pressure required for a flat seal even at high temperatures, it is suggested that the fuel cell unit comprise at least one supporting element which is arranged between the first housing wall and the second housing wall and keeps the two housing walls at a distance from one another.
US07740971B2 Separator for fuel cell and production process for the same
In order to provide a separator for a fuel cell which is improved in cell characteristics by controlling a wetting property of the separator for a fuel cell and a production process for the same, assumed is a constitution in which in a separator A for a fuel cell molded from at least from a carbon material, a hydrophilic functional group is formed and increased on a surface part of a flow passage surface 11 in the separator 10 by irradiation treatment of a YAG laser apparatus 20 and in which an uneven part having an average surface roughness Ra of less than 50 μm is formed.
US07740968B2 Ion-conductive binder membrane-electrode assembly and fuel cell
This invention relates to an ion-conducting binder used for a membrane electrode assembly for polymer electrolyte fuel cells, the assembly consisting of a polymer electrolyte membrane and two gas diffusion electrodes stuck to the polymer electrolyte membrane with the membrane put between the electrodes, which binder comprises a block copolymer which comprises a polymer block (A) having as a main unit an aromatic vinyl compound unit whose α-carbon is quaternary carbon, and a flexible polymer block (B), and has ion-conducting groups on the polymer block (A), and a solution or suspension thereof, and a membrane electrode assembly and a polymer electrolyte fuel cell.The ion-conducting binder, membrane electrode assembly and polymer electrolyte fuel cell of this invention are economical, mild to the environment and excellent in moldability and oxidation stability.
US07740967B2 Highly conductive ordered ion exchange membranes
Process for producing ion exchange membranes. A matrix material that comprises a polymeric component chosen from the group consisting of monomeric and oligomeric polymer precursors and cross-linkable polymers is provided. Ion cation or anion exchange particles, or proton or hydroxyl or ion conducting particles, or cation or anion exchange polymers, or proton or hydroxyl or ion conducting polymers are introduced in the matrix. The particles are mixed or the polymer is dissolved with the matrix. The resulting mixture is formed into membrane configuration. The particles or the domains of the polymer formed by polymer-matrix phase separation upon solvent evaporation or cooling, are ordered by an electric field. If the matrix comprises or consists of a polymer precursor or a cross-linkable polymer, the precursor is cured concurrently with the ordering of the particles, or if the matrix comprises a polymer solution or polymer melt the polymer solution is evaporated or the polymer melt is maintained and then cooled concurrently with the ordering of the particles.
US07740966B2 Electrochemical cell stack assembly
Multiple stacks of tubular electrochemical cells having a dense electrolyte disposed between an anode and a cathode preferably deposited as thin films arranged in parallel on stamped conductive interconnect sheets or ferrules. The stack allows one or more electrochemical cell to malfunction without disabling the entire stack. Stack efficiency is enhanced through simplified gas manifolding, gas recycling, reduced operating temperature and improved heat distribution.
US07740965B2 Battery
A battery includes a battery can housing an cell that supplies electrical energy at terminals of the cell by an electro-chemical reaction with oxygen, the can including, a first member having at least one hole that is exposed to air; and a second member. The battery also includes a mechanism coupled to one of the first and second members to move the one of the first and second members such that when current is drawn from the battery, the opening in the member allows air to pass into the battery, and to move the one of the first and second members such that when current is not drawn from the battery, the opening in the member is not in registration to inhibit air to pass into the battery. The battery also includes a circuit to control the mechanism. In one embodiment the circuit monitors levels of O2 in a air plenum that surrounds the cell. The circuit to monitor levels of O2 in the air plenum includes a florescent detector/sensor that senses and responds to changes in O2 in the plenum by using the “quenching effect” of oxygen on a fluorescent material.
US07740964B2 Adaptive anode nitrogen management control
A method is provided for controlling the concentration of nitrogen in a fuel cell stack. The method includes providing a fuel cell stack with cathode passages and anode passages including a valve in communication with the anode passages. The method further comprises selecting a maximum desired amount of nitrogen to be found in the fuel cell stack and calculating an actual amount of nitrogen in the fuel cell stack. Next, the method provides for comparing the maximum desired amount of nitrogen in the fuel cell stack to the actual amount of nitrogen in the fuel cell stack, and opening the valve if the actual amount of nitrogen in the fuel cell stack is greater than the maximum desired amount of nitrogen in the fuel cell stack. The method calculates the actual amount of nitrogen in the fuel cell stack based on an amount of nitrogen that enters the anode passages due to an age of the fuel cell stack.
US07740948B1 Thermal barrier coatings
This disclosure addresses the issue of providing a metallic-ceramic overlay coating that potentially serves as an interface or bond coat layer to provide enhanced oxidation resistance to the underlying superalloy substrate via the formation of a diffusion barrier regime within the supporting base material. Furthermore, the metallic-ceramic coating is expected to limit the growth of a continuous thermally grown oxide (TGO) layer that has been primarily considered to be the principal cause for failure of existing TBC systems. Compositional compatibility of the metallic-ceramic with traditional yttria-stabilized zirconia (YSZ) top coats is provided to further limit debond or spallation of the coating during operational use. A metallic-ceramic architecture is disclosed wherein enhanced oxidation resistance is imparted to the surface of nickel-based superalloy or single crystal metal substrate, with simultaneous integration of the yttria stabilized zirconia (YSZ) within the metallic-ceramic overlayer.
US07740946B2 Electroconductive laminate, and electromagnetic wave shielding film for plasma display and protective plate for plasma display
To provide an electroconductive laminate excellent in electrical conductivity and visible light transparency, an electromagnetic wave shielding film for a plasma display, and a protective plate for a plasma display having excellent electromagnetic wave shielding properties, a broad transmission/reflection band and a high visible light transmittance.An electroconductive laminate 10 comprising a substrate 11, and an electroconductive film 12 having a three-layer structure having a first oxide layer 12a, a metal layer 12b and a second oxide layer 12c laminated sequentially from the substrate 11 side, or having a 3×n layer structure (wherein n is an integer of at least 2) having the above three-layer structure repeated, wherein the first oxide layer 12a contains “zinc oxide” and “titanium oxide or niobium oxide”, the metal layer 12b is a layer containing silver, and the second oxide layer 12c contains a mixture of zinc oxide and aluminum oxide, or the like.
US07740941B2 Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein
This invention relates to thermoplastic article having one or more decorative materials embedded therein which is obtained by applying heat and pressure to one or more laminates wherein at least one of said laminates comprises, in order, (1) an upper sheet material; (2) one or more decorative materials; and (3) a lower sheet material; wherein the upper and lower sheet materials are formed from a polyester/aromatic polycarbonate blend wherein the thermoplastic article comprises at least one polyester composition comprising at least one polyester which comprises terephthalic acid and 2,2,4,4-tetramethyl-1,3-cyclobutanediol.
US07740935B2 Emblem for securing to an article
An emblem having a design for securing to an article by the application of at least one of heat and pressure comprises a base having a front surface and a rear surface, the base being comprised of a woven fabric. The emblem design is comprised of two portions, a first portion of the emblem design being woven into the fabric base when the fabric base is made and a second portion of the emblem design being embroidered into the fabric base. A layer of thermoplastic adhesive material is bonded to the rear surface of the fabric base for securing the emblem to the article.
US07740934B2 Optical low pass filter
An optical low pass filter includes: a plurality of optical elements formed by bonding together and an adhesion layer of adhesive that is installed at each of interfaces of the plurality of optical elements to be bonded. The transmitted wave aberration is ±1.5λ or less (λ representing incident wavelength).
US07740930B2 Stain-resistant flooring material
The present invention provides a flooring material including a base portion, a coating portion being positioned in contact with an upper surface of the base portion and creating an upper surface of the flooring material, wherein the coating portion is substantially free from contaminants from the base portion which decrease the stain resistance of the coating portion and wherein the coating portion includes a first particulate material which at least partially penetrates the base portion and is proud from the upper surface of the flooring material.
US07740925B2 Composite laminate and method of producing a composite laminate
The present invention provides a composite material including a substrate layer, a knit porous layer intermixed within the substrate material, and a thermoplastic layer disposed upon the porous layer. The porous layer is at least partially disposed within the thermoplastic layer. The present invention also provides a method for forming the composite material including the steps of: providing a substrate layer, providing a porous layer disposed on the substrate layer, providing a thermoplastic layer disposed on the porous layer, applying pressure and vacuum to mechanically interlock the thermoplastic layer with the porous layer; and bonding the porous layer to the substrate layer.
US07740923B2 Method and apparatus for producing a package or for packaging a food product
A package material with a tamper evident feature and methods of manufacture thereof, are disclosed herein. The package comprises a colored primer or lacquer coating applied along a portion of a seal and further comprising a peelable sealant. When opened the peelable sealant is separated from the portion of the seal containing colored primer or lacquer and removes a section of the coating, thus providing a visual indication that the package has been opened.
US07740922B2 Process for producing pipe sleeves from mineral wool
The invention relates to a process for producing pipe sleeves made of mineral wool for insulating pipelines or for reducing the sound level in pipeline systems, comprising the following steps: providing a nonwoven web (11) made of mineral wool which is provided with an uncured binder, winding up the nonwoven web (11) on a winding mandrel (2) of a winder, curing the binder. Here, at least one reinforcing layer (12, 13) is provided before the nonwoven web (11) runs into the winder, in such a way that during the winding the said reinforcing layer becomes a constituent part of the pipe sleeve produced as a result.
US07740921B2 Media sheet
A media sheet has a substrate with an image-receiving layer disposed thereon. The image-receiving layer has a first pigment having particles with a size of about 50 to about 400 nanometers, a second pigment having plate-like particles, and a third pigment that either having a porous structure with an oil absorption of about 50 to about 300 cubic centimeters of oil per 100 grams, or a porous structure comprising substantially non-porous particles.
US07740914B2 Method to manufacture metallized paper with curtain coating
The method comprises the stages of the curtain coating of a first aqueous film-forming composition on a substrate; and the curtain coating of a second aqueous film-forming composition on said metallized substrate, characterized in that said first and second aqueous film-forming composition comprises a first emulsion polymer and/or a second colloidal dispersion polymer.
US07740913B2 Copolymers for stain resistance
A method for imparting resistance to staining to a substrate comprising contacting the substrate with a copolymer comprising the monomers of Formula wherein D is at least one vinyl monomer selected from the group consisting of aryl olefin, alpha olefin and diene, each M is independently H, Ca, Mg, Al, Na, or K, each R1 is independently H, C1-C6 alkyl, or C1-C6 hydroxyalkyl, each R2 is independently linear or branched C1-C12 alkyl, C1-C6 hydroxyalkyl, C6F5, arylalkyl, C6H4OH, R3COOH, or R3SO3H, or R1 and R2 are linked together to form a morpholino or pyrrolidino ring, R3 is linear or branched C1-C12 alkyl, CH(COOH)CH2CH2, C6H4, or C6H3(OH), h1+h2 is h, h is a positive integer, k is zero or a positive integer, i and j are each independently zero or a positive integer, provided that the total of 1) h÷(k+h+i+j) is from about 0.005 to about 0.7, 2) k÷(k+h+i+j) is from about 0.3 to about 0.6, 3) [i+j]÷(k+h+i+j) is 0 to about 0.6, and provided that the sum of 1)+2)+3) is 1.0, said monomers occurring in any sequence.
US07740903B2 Method for manufacturing magnetic recording medium
A method for manufacturing magnetic recording media is provided, by which a magnetic recording medium that has a recording layer formed in a concavo-convex pattern, a sufficiently flat surface, and good recording/reproducing properties can be manufactured. The method includes the steps of: depositing a first filling material over a workpiece to cover recording elements formed as convex portions of the concavo-convex pattern, and to fill at least part of a concave portion; depositing a detection material over the first filling material; depositing a second filling material over the detection material; and irradiating a surface of the workpiece with a process gas to flatten the surface. In the flattening step, a component of the detection material removed from and flying off the workpiece is detected to stop the irradiation with the process gas based on a result of detecting the component of the detection material.
US07740897B2 Process for producing rigid reticulated articles
A method for forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout the volume and opening through the surface, includes, providing an organic open-pore structure, coating surface of pores of the structure with a ceramic slip, pyrolyzing the organic structure to leave a ceramic structure having struts defining a plurality of interconnecting interstices, and providing within the interstices a porous osteoconductive composition exposed to the interconnecting openings. In a preferred embodiment, the ceramic slip includes a strong, supportive ceramic material and a separate osteoconductive material.
US07740894B2 Fiber-containing rice-based cereals and methods of preparation
Methods for providing cooked rice with enhanced levels of fiber, wherein the fiber-containing cooked rice is suitable and especially adapted for use in preparing fiber-containing rice-based cereal products and especially for preparing fiber-containing puffed rice-based cereal products, are provided.
US07740893B2 Sports drink composition for enhancing glucose uptake into the muscle and extending endurance during physical exercise
The present invention provides for a nutritional composition in a dry powder form or a liquid drink form for optimizing muscle performance during exercise. The nutritional composition includes carbohydrate and protein in a ratio, in the range of 2.8 to 4.2 parts of the carbohydrate to 1.0 part of the protein. The carbohydrate is composed of a mixture of three sugars which are characterized by the fact that they are transported from the GI tract into the plasma via different transport pathways, specifically, the glucose pathway, the fructose pathway and the disaccharide pathway. One or more proteins are in the range of 10.29% to 32.25% by weight of the dry composition. The nutritional composition further includes electrolytes for replenishing electrolytes lost during exercise and for facilitating intestinal reabsorption of fluid. The carbohydrates are transported to the plasma via multiple transport pathways: one for glucose and similar sugars, another for fructose and similar sugars, and another for the complex sugars.
US07740887B2 Concentrated beverage composition for hair health care, method of manufacturing the concentrated beverage composition and natural tea comprising the same
Disclosed are a concentrated beverage composition for hair health care, a method of manufacturing the concentrated beverage composition, and a natural tea comprising the same. The concentrated beverage composition for hair health care comprises 100 parts by weight of water, 10 to 20 parts by weight of Pleuropterus multiflorus extract, 5 to 20 parts by weight of Sophora flavescens extract, 1 to 5 parts by weight of black bean extract, 5 to 10 parts by weight of African black sesame extract; 1 to 10 parts by weight of pomegranate extract; 5 to 10 parts by weight of Oenothera odorata seeds extract; and 5 to 10 parts by weight of Sophora japonica extract.
US07740883B2 Nanoparticles from chitosan
Methods are disclosed for preparing crosslinked core and core-shell nanoparticle polymers from chitosan. The final products of the present invention may be used as detergents and as additives for pharmaceutical composition and for drug delivery, and DNA carrier system. The nanoparticles made from biopolymers of the present invention may also be used in controlled release, superabsorbent materials and biomaterials like enzyme immobilization.
US07740880B2 Polymeric carrier for delivery of small interfering RNA
A carrier for delivering small interfering RNA (siRNA) into cells includes a cholesterol residue covalently bonded to oligoarginine. Mixing the siRNA with the carrier produces a complex-containing composition. Contacting a cell with the complex-containing composition results in delivery of the siRNA into the cell. Delivery of an siRNA targeted to vascular endothelial growth factor is a treatment for cancer. Methods of making the carrier and complex are also disclosed.
US07740875B2 Organo-gel formulations for therapeutic applications
A composition suitable for the local delivery of cosmetic and/or pharmaceutical agents into the skin containing at least two biocompatible organic solvents, a polar lipid, a surfactant, water, urea and a thickener wherein the organic solvents include an ester and a dihydric and/or polyhydric alcohol is provided. Also disclosed are compositions that further contain a cosmetic and/or pharmaceutical agent, along with the preparation and use thereof.
US07740872B2 Method of treating cancer cells to create a modified cancer cell that provokes an immunogenic response
The present invention relates to a delipidation method employing a solvent system useful for extracting lipids from cancer cells, thereby creating a modified cancer cell particle. Upon delipidation of the cancer cells, a portion of the cancer cell antigens remain intact. These exposed antigens, or epitopes, foster and promote antibody production. The resulting modified cancer cell particle, or portions of the cancer cell, initiate a positive immunogenic response when administered to an animal or human and help to treat, prevent or delay the onset of cancer. The present invention provides autologous and heterologous vaccine compositions comprising the modified cancer cell with a pharmaceutically acceptable carrier. The present invention provides method of administering these vaccines to treat, prevent or delay the onset of cancer.
US07740871B2 Cancer immunotherapy with a viral antigen-defined, immunomodulator-secreting cell vaccine
A human cell line, which lacks major histocompatibility class I (MHC-I) antigens and major histocompatibility class II (MHC-II) antigens and which has been modified to comprise and express (i) a nucleotide sequence encoding an immunomodulator and (ii) a nucleotide sequence encoding a viral antigen, and a method of inducing or stimulating an immune response in a human to a viral-associated disease or cancer comprising administering to the human (i) the aforementioned human cell line in an amount sufficient to induce or stimulate an immune response to the viral associated disease or cancer, (ii) a human cell line, which lacks MHC-I and MHC-11 antigens and which has been modified to comprise and express a nucleotide sequence encoding an immunomodulator, and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral-associated disease or cancer, or (iii) an immunomodulator and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral associated disease or cancer.
US07740863B2 Recombinant vaccine against West Nile Virus
An immunogenic or vaccine composition to induce an immune response or protective immune response against West Nile virus (WNV) in an animal susceptible to WNV. The composition includes a pharmaceutically or veterinarily acceptable vehicle or excipient, and a vector. The vector contains heterologous nucleic acid molecule(s), expresses in vivo in the animal WNV antigen, immunogen or epitope thereof, e.g., WNV E; WNV prM and E; WNV M and E; WNV prM, WNV M and E, WNV polyprotein prM-E, WNV polyprotein M-E, or WNV polyprotein prM-M-E. The composition can contain an adjuvant, such as carbomer. Methods for making and using such a composition, including prime-boost regimes and including as to differential diagnosis, are also contemplated.
US07740862B2 FSH mutants
FSH mutants with increased glycosylation and longer half-lives are described. The use of FSH mutants for inducing folliculogenesis in human patients is also described.
US07740859B2 Polypeptides for the diagnosis and therapy of Leishamaniasis
The present invention provides compounds and methods for the detection of anti-leishmanial antibodies in individuals suspected of infection with the protozoan parasite of the genus Leishmania, where the infectious agent is an Indian strain and similar or closely related to Indian Leishmania strains. The compounds provided include polypeptides as shown in SEQ ID NO: 5 or SEQ ID NO: 6 which are useful for the detection of anti-leishmanial antibodies in individuals where the immune responses are elicited against Leishmania species of Indian strains and similar or closely related to Indian Leishmania strains, the compounds are also useful as a vaccine and therapeutic agent to prevent and treat leishmaniasis. The present invention further provides a diagnostic kit consisting of antibody raised against polypeptides as shown in SEQ ID NO: 5 or SEQ ID NO: 6 for detecting leishmanial antigens.
US07740855B2 Inactivated CD8+ T-cells for the treatment of HIV infection
A method for the preparation of a T cell vaccine for the treatment of immunodeficient HIV-infected patients is described herein, based on the enrichment of autologous CD4-reactive CD8 T cells. Also described is a protocol for the implementation of T cell vaccination in immunodeficient HIV-infected, as well as a method of treatment, based on the T cell vaccine developed herein. Finally, kits for preparing the T cell vaccine as well as for implementing the protocol are also provided.
US07740848B2 Method of treatment of skin inflammation
Provided are methods for diagnosing the propensity of a subject to develop skin inflammation, in particular, psoriasis. Also provided are methods of treatment with antagonists of IL-17, IL-19, and/or IL-23.
US07740847B2 Variant Fc regions
The present invention provides humanized anti-CD20 antibodies comprising a human IgG1 Fc region comprising an isoleucine at position 247 and a glutamine at position 339 as well as nucleic acids encoding the antibodies and methods of using the antibodies for treating lymphoma. Furthermore, the invention provides compositions comprising the antibodies and methods of producing them.
US07740844B2 Anti-VEGF monoclonal antibody
The present invention provides novel monoclonal antibodies with a high binding affinity to all five isoforms of human VEGF.
US07740842B2 Stable liquid formulations of antibodies
The present invention provides stable liquid formulations of antibodies suitable for parenteral administration. Also, provided are aqueous solutions which have high concentrations of therapeutical antibodies which may be used to produce therapeutical liquid formulations. The present invention also relates to uses, such as medical uses, of the stable liquid formulations and processes for the production of the stable liquid formulations.
US07740840B1 High activity mutants of butyrylcholinesterase for cocaine hydrolysis
Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (−)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (−)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.
US07740835B2 Anaerobic bacterium as a drug for cancer gene therapy
The present invention provides a bacterium belonging to the genus Bifidobacterium, by which DNA coding for a protein having an antitumor activity or DNA coding for a protein having the activity of converting a precursor of an antitumor substance into the antitumor substance is delivered to tumor tissues specifically under anaerobic conditions thereby expressing the protein encoded by the DNA, as well as a pharmaceutical composition comprising said anaerobic bacterium.
US07740831B2 Compositions for potentiating glutathione
A composition for potentiating glutathione, which contains at least one member selected from the group consisting of 2-(3,4-dihydroxyphenyl)ethanol or a glycoside thereof, a plant containing 2-(3,4-dihydroxyphenyl)ethanol or a glycoside thereof, an extract of said plant, a hydrolysate of said plant, and a hydrolysate of the extract of said plant (excluding Olea europaea and an extract thereof), and which further contains at least one member selected from among an S-containing compound that is a supply source of cysteine, a protein that contains cysteine and/or cystine, a yeast that contains cysteine and/or cystine, and a vitamin.
US07740830B2 Imaging, diagnosis and treatment of disease
The present invention relates to endothelial cell-specific genes and encoded polypeptides and materials and uses thereof in the imaging, diagnosis and treatment of conditions involving the vascular endothelium.
US07740828B2 Process for preparing multimetallic anionic clays and products thereof
Multimetallic anionic clays (MACs) are prepared using economical raw materials or reactants and a procedure for obtaining a series of multimetallic mixed oxides derived from the thermal decomposition of the MACs which comprises: (1) dissolving water-soluble bimetallic and/or trimetallic sources in water, (2) dispersing and homogenizing separate water-insoluble divalent and/or trivalent metal precursors with a high-speed stirrer in order to obtain small and reactive particles; depending on the nature of the water-insoluble divalent and/or trivalent metal precursors, this process can be adjusted to a desired pH, (3) adding the suspension obtained in (2) to solution (1) with the reaction medium still dispersed to facilitate solid particle's reduction/dissociation, and (4) afterwards the slurry is aged for several hours and finally dried. This process enables raw materials or reactants to be easily handled, and eliminates unit operations involving product washing and/or purification steps.
US07740826B2 Method for functionalizing carbon nanotubes utilizing peroxides
A method for functionalizing the wall of single-wall or multi-wall carbon nanotubes involves the use of acyl peroxides to generate carbon-centered free radicals. The method allows for the chemical attachment of a variety of functional groups to the wall or end cap of carbon nanotubes through covalent carbon bonds without destroying the wall or endcap structure of the nanotube. Carbon-centered radicals generated from acyl peroxides can have terminal functional groups that provide sites for further reaction with other compounds. Organic groups with terminal carboxylic acid functionality can be converted to an acyl chloride and further reacted with an amine to form an amide or with a diamine to form an amide with terminal amine. The reactive functional groups attached to the nanotubes provide improved solvent dispersibility and provide reaction sites for monomers for incorporation in polymer structures. The nanotubes can also be functionalized by generating free radicals from organic sulfoxides.
US07740822B2 Method for purification of disilicon hexachloride and high purity disilicon hexachloride
The objective of the present invention is to provide a method for obtaining a high purity disilicon hexachloride by removing a silanol with good efficiency from a disilicon hexachloride material containing the silanol as an impurity. The purification method for disilicon hexachloride of the present invention comprises a process for contacting a disilicon hexachloride material containing disilicon hexachloride and a silanol as an impurity with an adsorbent material such as activated carbon to remove the silanol. The method may further comprise a distillation process. The above processes are preferably performed in an atmosphere of an inert gas.
US07740817B2 Catalyst for purifying exhaust emission from internal combustion engine, method for preparation thereof and method for purifying exhaust emission from internal combustion engine
A catalyst which efficiently removes particulate matter, SOF, sulfate, and SOOT and the like from the exhaust gas from such an internal combustion engine as a diesel engine without inducing a rise in the back pressure of the engine is provided. The catalyst for the purification of the exhaust gas of an internal combustion engine is formed by using an open flow honeycomb containing in the channel walls thereof such pores as possess an average diameter in the range of 10-40 μm.
US07740813B2 Automated endoscope reprocessor self-disinfection connection
An endoscope reprocessor having a water supply disinfection filter and a method for self-disinfection of the filter employ a pair of connectors to switch from a normal operating mode into a self-disinfection mode in which circulating germicidal fluid within the reprocessor flows through the filter, while the water supply remains connected to the system and isolated from the circulating fluid.
US07740812B2 Method and apparatus for separating aromatic dialdehyde
The present invention relates to a method and an apparatus for continuously separating aromatic dialdehyde from a reaction mixture obtained by gas-phase oxidation of dimethylbenzene. The method for continuously separating aromatic dialdehyde includes the steps of congealing aromatic dialdehyde by cooling the gas-phase reaction mixture including the aromatic dialdehyde, which is obtained by gas-phase oxidation of dimethylbenzene, to 5-70° C. and separating the congealed aromatic dialdehyde from the remaining reaction mixture. Using the method and apparatus in accordance with the present invention, aromatic dialdehyde can be effectively and selectively separated from a reaction mixture obtained by gas-phase oxidation of dimethylbenzene in high yield.
US07740809B2 Exhaust gas-cleaning apparatus
An apparatus for cleaning an exhaust gas containing nitrogen oxide and particulate matter and discharged from a diesel engine, wherein the apparatus comprises a porous ceramic honeycomb filter and an SCR catalytic converter in this order from upstream, wherein the honeycomb filter has pluralities of flow paths partitioned by porous cell walls and a catalyst supported by the porous cell walls, with desired flow paths sealed by plugs, and wherein at least one plug on the side of an exhaust gas inlet is separate inward from an exhaust gas inlet end. A ratio D/V of the diameter D (mm) of the honeycomb filter to the displacement V (liter) of the diesel engine is preferably 15 mm/liter or more. The honeycomb filter and an SCR catalytic converter are preferably contained in one case.
US07740807B2 Microfluidic device including displaceable material trap, and system
A microfluidic device is provided that can include an input liquid-containment feature. The microfluidic device can include an overflow channel in fluid communication with the input liquid-containment feature. The microfluidic device can include a fluid capture appendix in fluid communication with the overflow channel.
US07740806B2 Ceramic microarray spotting device for bioassay printing
Methods of making and the resultant micro-spotting plates having a plurality of feed holes, a plurality of dispensing nozzles, an open cavity in communication with the dispensing nozzles and a plurality of channels. The channels connect the feed holes to the dispensing nozzles for transferring a fluid from the feed holes to the dispensing nozzles under a capillary force. A channel may connect a single feed hole retaining a liquid to a dispensing nozzle for dispensing such liquid, or a channel may connect two or more feed holes to a dispensing nozzle for enabling mixing of fluids from the feed holes within the channel prior to dispensing such mixture. The micro-spotting plates allow the continuous self-feeding flow of fluids by capillary forces through its hydrophilic layers for enabling the controlled dispensing of a multi-array of drops of fluids onto a substrate, preferably a test slide, for later use.
US07740801B2 System for determination of an analyte in a bodily fluid sample that includes an electroluminescent component
A system for the determination of an analyte in a bodily fluid sample includes an analytical test strip and an analytical meter. The analytical test strip has a substrate layer, an electroluminescent component (either an electroluminescent module and/or an electroluminescent lamp) disposed on the substrate layer, and a sample chamber configured for receiving a bodily fluid sample disposed above the substrate layer. Moreover, the analytical meter is configured for insertion of the analytical test strip therein and subsequent determination of the analyte.
US07740800B2 Extracorporeal blood circuit air removal system and method
A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.
US07740799B2 System for, and method of, irradiating opposite sides or articles with optimal amounts of cumulative irradiation
Opposite sides of an article are irradiated to sterilize the article. The cumulative irradiation should be above a first value, and below a second value greater than the first value, at all of the positions in the article to provide the article with desired radiation benefits. Any amount of cumulative radiation between the first and second values is considered as optimal values. For a first range of article thicknesses, the cumulative radiation in the article is at the optimal values. For article thicknesses in a second range greater than in the first range, the cumulative radiation at positions in the article is greater than the optimal values. For article thicknesses in a third range greater than the second range, the cumulative radiation at the different positions in the article is at the optimal values. For the thicknesses in the second range, a member disposed in the radiation path weakens the radiation passing to the article, thereby reducing the cumulative radiation to an optimal value. For each thickness in the second range, a different amount of cumulative radiation above the optimal value may occur when the member is not disposed in the radiation path. The member may accordingly be provided with different thicknesses, dependent upon the amount of the cumulative radiation in the article for the different positions in the second thickness range, to reduce the cumulative radiation in the article to an optimal value. A system may automatically position the member properly for article thicknesses in the second range.
US07740798B2 Alloy compositions and devices including the compositions
Alloy compositions, including devices and instruments that include the compositions, are disclosed. The compositions have high hardness, strength, corrosion resistance, and biocompatibility. The compositions can be used to manufacture, for example, medical devices and products.
US07740796B2 Iron silicide powder and method for production thereof
Provided is iron silicide powder in which the content of oxygen as the gas component is 1500 ppm or less, and a method of manufacturing such iron silicide powder including the steps of reducing iron oxide with hydrogen to prepare iron powder, heating the iron powder and Si powder in a non-oxidizing atmosphere to prepare synthetic powder containing FeSi as its primary component, and adding and mixing Si powder once again thereto and heating this in a non-oxidizing atmosphere to prepare iron silicide powder containing FeSi2 as its primary component. The content of oxygen as the gas component contained in the iron silicide powder will decrease, and the iron silicide powder can be easily pulverized as a result thereof. Thus, the mixture of impurities when the pulverization is unsatisfactory will be reduced, the specific surface area of the iron silicide powder will increase, and the density can be enhanced upon sintering the iron silicide powder.
US07740792B2 Methods of molding a syringe
A syringe for use in a pressurized injection of a fluid includes a syringe barrel including a polymeric material having undergone expansion via blow molding. An inner diameter of the syringe barrel can, for example, be sufficiently constant (over at least a portion of the axial length of the syringe) that a plunger slidably positioned within the syringe barrel and in generally sealing contact with an inner wall of the syringe barrel can be used within the syringe barrel to generate a pressure of at least 1 psi within the syringe barrel. In several embodiment, the inner diameter of the syringe barrel is sufficiently constant to generate a pressure of at least 100 psi, at least 300 psi, or even at least 500 psi within the syringe barrel. A method of forming a syringe includes the steps of: injection molding at least one polymeric material to form a preform; placing the preform into an blow mold die; and expanding at least a portion of the preform while heating the preform within the die to form a barrel of the syringe. The syringes can be formed to withstand relatively high pressures as described above. The at least one polymeric material can, for example, be polyethyleneterephthalate, cyclic olefin polymer, polypropylene, polystyrene, polyvinylidene chloride, polyethylene napthalate and/or nylon.
US07740791B2 Method of fabricating a stent with features by blow molding
The invention provides a method of manufacturing a stent, the method comprising: disposing a polymeric tube into a cylindrical mold, the cylindrical mold having a variable diameter along a portion of the inside surface of the mold; radially expanding the tube by blowing a gas or liquid into the cylindrical mold, the outside surface of the tube conforming to the variable diameter portion of the outside surface of the mold, causing the radially expanded tube to have a variable diameter along the conformed length of the tube; and fabricating a stent from the expanded tube.
US07740787B2 Flexible carrier mold
A carrier mold having prongs that produces shaped tampons is provided. When subjected to pressure the prongs of the carrier mold flex to completely or substantially close one end of the carrier mold. A method of forming a shaped tampon using the carrier mold is also provided.
US07740785B2 Closure cap with injection molded annular gasket and method of making same
A closure cap and method of making the same wherein an annular or ring-shaped gasket is injection molded onto the inner surface of a cap shell formed of plastic or metal. The annular or ring-shaped gasket includes at least one radially extending tab integrally formed therewith. A channel in the working surface of a mold core cooperates with the inside surface of the cap to form a mold cavity having the shape of the gasket to be formed therein. The cavity includes a melt inlet and a melt outlet which is in flow communication with a cold well through a connecting portion of reduced cross-sectional area with respect to the cross-sectional areas of both the gasket-defining mold cavity and the cold well.
US07740780B2 Multitube catheter and method for making the same
Multitube catheter and method for making the same are provided. The assembly includes two or more tube fused together to form one catheter tube shaft. Each tube has at least one lumen extending longitudinally through the catheter from its distal end to its proximal end. The tubes are fused together by use of heat & pressure. Heat and pressure can be generated by heat sensitive tube slides over a segment of catheter tubes while metallic mandrels are passed through each tube lumen to protect the lumens during fusion. The heat sensitive tube will shrink once heat is applied. The heat sensitive tube will shrink and apply the required pressure over the catheter tubes. Continual heating will melt and re-shape the catheter tubes inside the heat sensitive tube while the letter will not be affected due to its high melting temperature. After cooling, the heat sensitive tube is to be removed, the metallic mandrels are pulled back and the tubes forming the united catheter tube. Distal end of the united catheter tube can be splited to form split tip, stepped tip or can be tapered tipped. The proximal segment (none fused) will form catheter extension legs. The pressure applied can also be created by silicon or rubber tube stretched over the catheter tubes, in a mould, by coextrusion, by over molding, through adhesions are other possible methods.
US07740776B2 Method for foam injection molding of thermoplastic resin
A method for injection foaming molding of a thermoplastic resin includes the steps of (1) injecting the foaming-agent-containing plasticized resin from an injection apparatus 30 to fill a mold cavity 10a, (2) releasing a clamping force of a mold 10 immediately after the foaming-agent-containing plasticized resin is injected and filled into the mold cavity 10a, so as to release the pressure of the foaming-agent-containing plasticized resin in the mold cavity 10a, (3) maintaining the pressure-released state of the foaming-agent-containing plasticized resin in the mold cavity 10a for a predetermined period of time, (4) expanding the mold cavity 10a to foam the foaming-agent-containing plasticized resin, and (5) cooling and maintaining the foaming-agent-containing plasticized resin while the mold cavity 10a is in the expanded state.
US07740774B2 Resonantly enhanced photosensitivity
A resonant enhanced photosensitive material includes a trap center that is adapted to interact with light and enhances the photosensitivity of the material based on a resonant interaction process with photons. The invention provides enhanced photosensitivity materials and, especially a method for enhancing photosensitivity in glasses, glass ceramics and ceramics.
US07740772B2 Ceramic anodes and method of producing the same
The present invention generally relates to ceramic anodes for use in solid oxide fuel cells, whereby the anodes are comprised primarily of ceramic material.
US07740766B2 Methods for treating water
Disclosed is a method of providing potable water that includes providing a filter, passing water through the filter, and removing bacteria and viruses from the water with the filter. The filter comprises a housing having an inlet and an outlet and a filter material disposed within the housing, the filter material formed at least in part from a plurality of mesoporous wood activated carbon filter particles and particles selected from the group consisting of mesoporous wood activated carbon filter particles coated entirely with a cationic polymer, mesoporous wood activated carbon filter particles partially coated with a cationic polymer, and mixtures thereof. A sum of mesopore and macropore volumes of the filter particles may be between about 0.2 mL/g and about 2 mL/g, wherein mesopore means an intra-particle pore having a diameter between 2 nm and 50 nm, and macropore means an intra-particle pore having a diameter greater than 50 nm, a total pore volume of the filter particles is greater than about 0.4 mL/g and less than about 3 mL/g, and a ratio of the sum of the mesopore and macropore volumes to the total pore volume of the filter particles is greater than about 0.3. The filter removes bacteria and viruses from the water at a level of Filter Bacteria Log Removal of greater than about 2 logs and a Filter Viruses Log Removal of greater than about 1 log.
US07740761B2 Screening Apparatus
The present invention provides a vibratory screening apparatus (1) for use in removing solids from a liquid feed, and a basket (4) therefore. The apparatus comprises a static outer housing (2), and a floating basket vibratable by a vibrator device (10). The basket mounts a stack (7) of screen assemblies (8) provided with respective flow directing trays (9) for receiving filtrates from the screen assemblies. A flow distributor (15) divides the feed into at least first and a second feed streams and directs them onto respective screen assemblies, and receives from the flow directing trays, filtrates from respective screen assemblies.
US07740756B2 Wastewater filter system
A filter unit for use in a casing disposed in a septic tank comprising a plurality of stacked filter plates. The individual filter plate is preferably substantially “D” shaped in circumference and has a substantially cone-shaped floor, tapering upward. The filter plates are preferably stacked in a superposed, spaced-apart manner with a particular diameter in relationship to the inner diameter of the case. The filter plates are preferably inserted into the filter case to define a seal horizontally around the bottom opening in the case, thereby allowing wastewater to enter into the filter plates to begin the filtering process. Solids preferably flow upward into the filter plates, where they are separated by size with a predetermined gap in the stacked filter plates.
US07740750B2 Application of visbreaker analysis tools to optimize performance
A system and method for quantifying opaque inhomogeneities within a fluid sample. The system uses an optical lens system to focus a light beam onto a stage where the sample is introduced. The light beam is directed onto the sample in a pattern such that the intensity of transmitted light is measured as a function of path length. A photo detector measures the transmitted light through the sample. Fluctuations in transmitted light intensity are then correlated with detection of opaque inclusions in the sample. The system also includes an automated program which utilizes these optical concentration measurements to determine the fouling potential of visbroken tars, and regulates the introduction of chemical inhibitors into a visbreaker unit to improve the yield of light streams and/or economic value of product.
US07740744B2 Method and apparatus for removing residual tissue from parent rolls
Cellulosic based cores used in manufacture of towel and tissue products can be effectively stripped of residual product with little damage to the core using a roll stripping air knife with a longitudinal air passageway having both primary discharge passages and interconnected auxiliary orifices, the auxiliary orifices are directed laterally away from the primary discharge direction and connect with a longitudinal exterior channel configured such that air flows inwardly through the auxiliary orifices when pressurized air is supplied to longitudinal air passageway and the primary discharge passages are unobstructed but outwardly when the primary discharge passages are obstructed so that the pressure achievable when the primary discharge passages are obstructed is within safety limits.
US07740743B2 Fine particle size lime slurries and their production
A polymer comprising i) a synthetic polymeric component that has been formed from an ethylenically unsaturated water-soluble or potentially water-soluble monomer and an ethylenically unsaturated monomer carrying a reactive group, wherein the reactive group is directly reactive with a cellulose binding domain protein; and ii) a protein component consisting of a cellulose binding domain protein, wherein the cellulose binding domain protein. The polymer is particularly suitable as a dry strength resin in a paper making process. It can also be used as a wet strength resin, internal sizing agent or surface sizing agent.
US07740740B2 Low density paperboard articles
The invention provides a low density paperboard material and associated method for use in producing an insulated container, and is especially well-suited for making cups. The paperboard material comprises a paperboard web including wood fibers and expanded microspheres, and has a relatively low density ranging from about 6 to about 10 lb/3 MSF/mil, a relatively high caliper ranging from about 24 to about 35 mil, and an internal bond strength of at least about 80×10−3 ft-lbf., preferably at least 100×10−3 lft-lbf. For applications such as cups the material is also coated on one or both sides with a barrier coating, preferably low density polyethylene, to limit liquid penetration into the web. The low density paperboard material of the invention is convertible for manufacture of containers, particularly cups, and exhibits insulative properties comparable to higher cost materials conventionally used to make cups. Also, the surface of the low density board may have a Sheffield smoothness of 300 SU or greater compared with the surface smoothness of 160 to 200 SU for conventional cupstock, the latter having been thought necessary for adequate print quality. However, it has been found that the low density board exhibits good printability on flexo printing machines despite its relatively rough surface, which is surprising and bonus effect realized along with the insulative and other properties of the board.
US07740739B2 Plasma processing apparatus and method
A plasma processing apparatus includes a gas ring forming a portion of a vacuum processing chamber and having a blowing port for a processing gas, a bell jar to define a vacuum processing chamber, an antenna for supplying an RF electric field into the vacuum processing chamber to form plasmas, a sample table, a Faraday shield, and a deposition preventive plate attached detachably at least to the inner surface of the gas ring excluding the blowing port. An area of the inner surface of the gas ring including the deposition preventive plate that can be viewed from the sample surface is set to about ½ or more of the area of the sample. A susceptor made of a dielectric material covers the outer surface and the outer lateral side of the sample table. A metal film is disposed with respect to the susceptor, and an RF voltage is applied to the metal film.
US07740736B2 Methods and apparatus for preventing plasma un-confinement events in a plasma processing chamber
Techniques and apparatus for substantially reducing and/or preventing the occurrence of plasma un-confinement events, including one or more of shielding a gap disposed between chamber components and along a RF current path with a dielectric shielding structure, shielding a sharp component structure with a dielectric shielding structure, and keeping the gap between adjacent pairs of plasma confinement rings smaller than the worst-case DeBye length for the plasma.
US07740726B2 Silicone fishing lure skirt with foil or holographic film and method of making the same
An elastomer fishing lure skirt comprising a silicone based elastomer substrate having a rough side wherein the substrate is separated into a plurality of filaments. The lure skirt further comprises an adhesive such as Chemlock 697, RTV adhesive, Lock Tight, or combinations thereof. The lure skirt further comprises a biaxially-oriented polyethylene terephthalate polyester film having a metalized foil, colored foil, holographic film, or combinations thereof bonded to its surface. Additionally, the lure skirt includes a means for semi-permanently binding the filaments together to form said lure skirt.
US07740725B2 Thick film conductor paste composition for LTCC tape in microwave applications
This invention is related to thick film conductor compositions comprising electrically conductive gold powder, one or more glass frit or ceramic oxide compositions and an organic vehicle. It is further directed to the composition's uses for LTCC (low temperature co-fired ceramic) tape, for fabrication of multilayer electronic circuits and in high frequency microelectronic applications.
US07740724B2 Method for preventing formation of cellular gamma prime in cast nickel superalloys
A method for preventing the formation of cellular gamma prime in nickel-based superalloys comprises the steps of: casting a nickel-based superalloy into a desired article; subjecting the cast article to hot isostatic pressing at a temperature in excess of 2000° F. at a pressure greater than 15,000 psi to close internal pores in the cast article; and avoiding any formation of the cellular gamma prime in the cast article.
US07740723B2 Controlled-grain-precious metal sputter targets
A precious metal sputter target has a composition selected from the group consisting of platinum, palladium, rhodium, iridium, ruthenium, osmium and single-phase alloys thereof. The sputter target's grain structure is at least about 99 percent recrystallized and has a grain size of less than about 200 μm for improving sputter uniformity. The cryogenic method for producing these sputter targets is also effective for improving sputter performance for silver an gold sputter targets.
US07740719B2 Cutter composed of Ni-Cr alloy
A cutter is composed of a Ni—Cr alloy containing from 32 to 44 mass percent of Cr, from 2.3 to 6.0 mass percent of Al, the balance being Ni, impurities, and additional trace elements and having a Rockwell C hardness of 52 or more. This Ni—Cr alloy provides a cutter produced with a superior workability and by a significantly simplified process, having a low deterioration in the hardness even when heated in use, having excellent corrosion resistance and low-temperature embrittlement resistance, and satisfactorily maintaining the cutting performance for a long time.
US07740711B2 Parts washer heater pump module
A parts washer including magnets located near a pump inlet to collect metallic particles suspended in the cleaning fluid; a casing to protect the pump mechanism from impact during handling; the pump oriented horizontally to take advantage of the separation of the cleaning fluid in successive vertical layers; two liquid level sensors to measure the level of the cleaning fluid in the reservoir; an evaporation control plate located at the interface between the reservoir and the receptacle of the reservoir to confine the vapor portion of the cleaning solution; protective handlebars placed next to the controls of a control module to protect the device from impact; and a pump motor control to provide a low flow rate of cleaning fluid using a pump without a variable regulator.
US07740710B2 Use of a mixture of esters of fatty acids as fuel or solvent
The present invention relates to the use of a mixture, comprising one or more alkyl esters of fatty acids and one or more esters of fatty acids of glycerol carbonate, as a fuel or solvent.
US07740708B2 Thermal fluid stimulation unit
A reservoir cleaning, treating and/or stimulation system allows the operator to control the speed and pressure of delivery of the treating fluid into the reservoir and remove or dissolve sediment particles settled in the reservoir or the reservoir formation. The system uses a thermal heater capable of heating the treating fluid from ambient temperature to about 400 degrees Fahrenheit. A charge pump mounted on an intake side of the heater forces the treating fluid through the heater, while the treating fluid passes through the tubing of the heater. The heated treating fluid is channeled to a discharge pump on an outlet side of the heater, where the treating fluid is pressurized to a value sufficient to overcome the pressure existing within the reservoir and cause displacement or dissolution of the sediment in the reservoir. A flow meter mounted between the heater and the charge pump regulates the volume of the treating fluid being admitted into the heater. A plurality of sensors and gauges strategically mounted within the system ensure safe operation of the system in the field. The system is mounted on a portable skid that can be delivered to the field and removed upon completion of the cleaning, treating and/or reservoir stimulation operation.
US07740701B2 Adhesive composition with lightweight filler
A hydraulically setting mortar composition containing at least one hydraulically setting component, at least one lightweight filler, at least one cellulose ether, at least one setting retarder and optionally further additional additives, particularly fillers and/or dispersion powders. In addition, a premix for producing a hydraulically setting mortar composition is described containing at least one lightweight filler and at least one cellulose ether and/or a setting retarder. As a result of the inventive ratio of these components, it is possible with much lower lightweight filler contents to obtain more cost effective mortar formulations and/or improved use characteristics, such as e.g. increased adhesive tensile strengths and/or an increased open time. The hydraulically setting mortar composition can be used in gypsum, gypsum-lime, lime-cement, cement and/or thermal plasters, tile adhesives, masonry mortars, full heat protection mortars, surfacers, self-levelling floor materials or repair mortars.
US07740696B2 Water-soluble azo compound, ink composition, and colored article
The present invention relates to a water-soluble azo compound for yellow represented by the following formula (1) wherein, A represents a hydroxy group, a morpholino group, an amino group, an aliphatic amine residue which may have a substituent, an aromatic amine residue which may have a substituent, a phenoxy group which may have a substituent, or an alkoxy group which may have a substituent, R1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R2 represents a hydrogen atom, a nitro group or a hydroxy group, and n represents an integer number of 1 to 3, respectively as a free acid, and an ink composition containing the same; said ink composition has good stability and is suitable for inkjet printing; and printed matters therewith have very high fastness such as ozone fastness and the like.
US07740695B2 Ink set, ink cartridge, inkjet recording method, and recorded matter
An ink set containing at least a yellow ink composition, a magenta ink composition, and a cyan ink composition: said magenta ink composition containing as a colorant at least one type of compound expressed by the formula M-1 in claim 1, and at least one type of compound expressed by the following formula M-2 in claim 1, the yellow ink composition containing as a colorant at least one type of compound expressed by the formula Y-1 in claim 1; and the cyan ink composition containing as a colorant at least one type of compound selected from the group consisting of compounds or salts thereof expressed by the Formula C-1 in claim 1.
US07740693B2 Organic fluorescent sulfonyl ureido benzoxazinone pigments
The present disclosure provides Benzoxazinone compounds represented by the formula: wherein each R1, R2, R3, and R4 is independently selected from hydrogen, alkyl of 1-12 carbon atoms, substituted alkyl, aryl of 6-12 carbon atoms, substituted aryl, halo, and alkoxy; and R5 is selected from alkyl of 1-12 carbon atoms, substituted alkyl, aryl of 6-12 carbon atoms, substituted aryl, halo, and alkoxy; wherein each of the substituted alkyl and the substituted aryl groups have a substituent selected from alkyl, aryl, halo, and alkoxy. The present disclosure provides a mark having a benzoxazinone compound, and a method for applying the mark onto an article. Also provided is a process for preparing benzoxazinone compounds.
US07740691B2 Gas treating method and apparatus
A method and apparatus for treating natural gas comprises a contactor having a manifold for spreading gas in the contactor vessel, a plurality of perforated plates above the manifold, a spray system for spraying a treating liquid into an upwardly rising column of gas and a liquid level controller for maintaining the treating liquid above the perforated plates. Gas and liquid from the contactor pass through a cooler and are then separated. A treating liquid regeneration system receives the treating liquid and flashes the liquid at low pressure to separate hydrocarbon gases, hydrocarbon liquid and treating liquid. The treating liquid is regenerated by heating and flashing off contaminant gases and is ultimately redelivered to the contactor.
US07740688B2 Process and apparatus for carbon dioxide recovery
The present invention generally relates to vacuum pressure swing adsorption (VPSA) processes and apparatus to recover carbon dioxide having a purity of approximately ≧90 mole % from streams containing at least carbon dioxide and hydrogen (e.g., syngas). The feed to the CO2 VPSA unit can be at super ambient pressure. The CO2 VPSA unit produces three streams, a H2-enriched stream, a H2-depleted stream and a CO2 product stream. When the CO2 VPSA unit is installed between an SMR/shift reactor and a H2 PSA unit, hydrogen recovery is expected to be increased by extracting CO2, thereby increasing hydrogen partial pressure in the H2 PSA feed. The stream from the CO2 VPSA unit, normally used as fuel, is recycled as feed to increase CO2 recovery. The recovered CO2 can be further upgraded, sequestered or used in applications such as enhanced oil recovery (EOR).
US07740687B2 Pressure swing adsorption method and system for separating gas components
A pressure swing adsorption method for separating gas components includes pressurizing an adsorption bed to an adsorption pressure using a first gas component of a feed gas, the adsorption bed including an adsorbent for substantially adsorbing a second gas component of a feed gas; introducing the feed gas to the pressurized adsorption bed, wherein the first gas component of the feed gas substantially passes through the pressurized adsorption bed and the second gas component of the feed gas substantially adsorbs onto the adsorbent; and depressurizing the pressurized adsorption bed to recover at least a portion of the second gas component of the feed gas in the pressurized adsorption bed.
US07740683B2 Powder for manufacturing precious metal products by free forming fabrication and products
The present invention relates to metal powders mixtures which are intended for manufacturing precious metal products which have special designs and complex geometries, also including those which consist of several uninterrupted parts which are indivisibly but flexibly coupled to each other. From the powder mixture jewelry and other objets d'art are manufactured by making use of free form fabrication (FFF) technique. The invention also comprises jewelry and other ornamental products which are manufactured from the powder material in question using the FFF technique.
US07740682B2 High-density composite material containing tungsten powder
An improved composite material, and method of manufacture thereof, comprising varying amounts tungsten powder, or metal/alloy powder of similar density, and clay or silicone is disclosed. The improved composite material may be useful as a replacement for lead and lead-based composites where similar densities are required but the use of lead is undesirable. The disclosed composite material permits a large variety of tungsten powder particle sizes to be utilized and results in improved ductility over known tungsten powder composites.
US07740681B2 Reductant addition in a channel induction furnace
A method of operating a channel induction furnace to process a feed material and obtain therefrom at least one of a molten metal product, a vapor phase metal product and a slag product. A molten metal bath is maintained in the channel induction furnace and the method includes adding a reductant such as carbon or a carbon containing material directly into the molten metal bath independently of the feed material.
US07740677B2 Oil separator
In order to provide an oil separator for separating oil from a blowby gas of a cylinder head of an internal combustion engine, which oil separator is manufactured separately from a basic body of a cylinder head cover but may nevertheless be easily integrated into the cylinder head cover, it is proposed that the oil separator comprises an oil separator module, which is manufactured separately from a basic body of a cylinder head cover and comprises a cyclone plate having at least one cyclone as well as a base plate, wherein the cyclone plate is fastened to the base plate and the oil separator module is fastenable to the basic body of the cylinder head cover.
US07740675B2 Cyclonic vacuum cleaner
A surface cleaning apparatus comprises a dirt inlet, a handle, a cyclonic cleaning unit comprising a plurality of cyclones and at least one dirt collection chamber, each of the plurality of cyclones having an outer wall, an interior, a fluid inlet downstream from the dirt inlet and a fluid outlet, the at least one dirt collection chamber having an outer wall and an interior, wherein the surface cleaning apparatus is constructed such that the interior of the at least one dirt collection chamber is visible from a position exterior to the surface cleaning apparatus and a fluid flow motor. The surface cleaning apparatus may have a filter with a housing that is at least partially transparent.
US07740672B2 Method and apparatus for a coal gasifier
A method and apparatus for efficiently forming a gaseous material from a solid starting material. The produced gaseous material includes a CGE HHV having a high percentage of an original HHV of the starting material. The gaseous product may be used to form a plurality of materials for various purposes.
US07740658B2 Intervertebral disk prosthesis methods of use
A method of using an intervertebral disk prosthesis includes the step of ensuring that the intervertebral space between first and second vertebrae of a patient is substantially free of nuclear matter. The method also includes the step of inserting a distal end of the disk prosthesis into a gap between the first and second vertebrae. The disk prosthesis includes a first part with a convexly-shaped and rounded outer surface and an inner surface having a concavely-shaped socket. The disk prosthesis also includes a second part that has a convexly-shaped and rounded outer surface and an inner surface that has a convexly-shaped portion that at least partially engages with the socket thereby allowing at least two-degrees of freedom of movement of the first part with respect to the second part. The method further includes the step of permitting the top of the first part to contact the first vertebra and the bottom of the second part to contact the second vertebra.
US07740657B2 Soft tissue sock enhancement devices
A sheath for organizing soft tissue includes a first tube having a flexible body sized and shaped to receive a fixation device, and a second tube coupled to the first tube having a flexible body sized and shaped to receive a soft tissue graft. A method for implanting soft tissue in a bone tunnel includes coupling a soft tissue graft to a sheath assembly; and positioning the sheath assembly relative to the soft tissue graft based on a measured depth of a bone tunnel. A set of surgical devices for implanting soft tissue grafts in a bone tunnel includes a sheath assembly, a measurement device for measuring the depth of the bone tunnel, a securing element configured to secure the sheath assembly to the soft tissue graft at a position determined by the measured bone tunnel depth, and a tensioning device configured to organize a plurality of soft tissue grafts.
US07740656B2 Implantable heart valve prosthetic devices having intrinsically conductive polymers
A heart valve sewing prosthesis including an intrinsically conductive polymer. The invention includes annuloplasty rings and bands, and sewing rings or cuffs for prosthetic heart valves. Some annuloplasty rings and sewing rings include fabric that is coated with an intrinsically conductive polymer. The coating can be formed over individual filaments or fibers, or on the fabric surface as a surface layer. One intrinsically conductive polymer is polypyrrole. The intrinsically conductive polymer can be doped to facilitate the intrinsic conductivity. Some devices have a polypyrrole surface layer doped with dialkyl-napthalene sulfonate. The intrinsically conductive polymer can be deposited on a fabric using in-situ polymerization of monomeric or oligomeric species, together with a dopant. Animal studies using implanted annuloplasty rings having an intrinsically conductive polymer coating have demonstrated a substantial reduction in pannus formation and inflammatory response.
US07740655B2 Reinforced surgical conduit for implantation of a stented valve therein
A pulmonary valve replacement system having a vascular conduit and a prosthetic valve device including a valve operably connected to a support structure. The prosthetic valve device is positioned within the vascular conduit. A conduit support includes a substantially circular cross-section. The conduit support is positioned adjacent to and reinforces the vascular conduit. In one embodiment, the pulmonary valve replacement system includes a catheter and an inflatable member operably attached to the catheter. The prosthetic valve device is disposed on the inflatable member. The invention provides a method for replacing a pulmonary valve including providing a vascular conduit positioned at a treatment site. The vascular conduit includes a conduit support positioned adjacent the vascular conduit. A prosthetic valve device is deployed within the vascular conduit via catheter. The prosthetic valve device includes a valve operably connected to a support structure. The vascular conduit is supported with the conduit support.
US07740649B2 Bone plate system and methods
Bone plate systems and anchor retainers are provided for use in surgical implants and bone repair. In a preferred form, the bone plate may include bores for receiving the bone anchors, and the bores may permit and define a path of translation or shifting of the bone anchors relative to the bone plate. The anchor retainers may be held in the bores to prevent back-out of the bone anchors. Once the anchor member is seated within the bone plate, the retainer may rest over a top surface of the anchor member so the anchor member is impeded from backing out of the bone plate. The retainer may expand or change shape to permit an anchor member to be driven through the retainer and may contract once an anchor member has been seated within the plate. In addition, a tool for insertion or extraction of the bone anchors is provided.
US07740648B2 Locking bone plate
A bone plate(s) of complex form is provided, particularly suited to tibial plateau-leveling osteotomy and a distal femoral osteotomy. The bone plate has a main longitudinal axis, a bone-contacting bottom side (not shown) and a top side with at least three sets of overlapping holes which communicate through the plate from the top to the bottom side. The sets of overlapping holes define threaded apertures having multifaceted surfaces. When applied to a bone, two sets of such overlapping holes are located so as to lie on opposite sides of an osteotomy site and on the tibial plate; a third is aligned at approximately 60 degrees with the longitudinal axis. The configuration of this complex bone plate vary, depending on the physiology of the patient. An object of the invention is to provide an orthopedic surgeon greater flexibility of choice in that a threaded peg providing secure fixing can be positioned at any interval along the bone plate, including at its extreme ends or on its elbow.
US07740642B2 Method for treating naturally obstructed paranasal sinuses
A method of treating a patient's paranasal sinus having an obstructed or narrowed naturally occurring bony and mucosal ostium or duct which does not have scar tissue or granulation tissue. A balloon of a balloon catheter is inflated in the obstructed or narrowed naturally occurring bony and mucosal ostium or duct to enlarge the naturally occurring bony and mucosal ostium or duct. The ostium or duct remains enlarged after the balloon catheter is removed.
US07740641B2 Clip applier with migrational resistance features
A surgical clip applier and methods for applying surgical clips to a vessel, duct, shunt, etc., during a surgical procedure are provided. In one exemplary embodiment, a surgical clip applier is provided having a housing with a trigger movably coupled thereto and a shaft extending therefrom with opposed jaws formed on a distal end thereof. The trigger is adapted to advance a clip to position the clip between the jaws, and to move the jaws from an open position to a closed position to crimp the clip positioned therebetween. The surgical clip applier can include a variety of features to facilitate use of the device, including features to align a clip with the jaws, features to prevent unintentional migration of a clip, and features to prevent clip fallout during formation.
US07740640B2 Clip apparatus for closing septal defects and methods of use
A device for closing a septal defect, such as a patent foramen ovale, includes a clip formed from a superelastic material that is inserted into a septum wall of a heart. The clip is advanced through a patient's vasculature, e.g., within a delivery apparatus, until the clip is disposed within a first chamber adjacent the septal defect. Tines of the clip are directed through a flap of tissue of the septal defect until the tines of the clip are disposed within a second opposing chamber. The clip then transforms into its relaxed state, wherein the tines of the clip engage with a surface of the second chamber, thereby substantially closing the septal opening.
US07740639B2 Method and device for the endoscopic application of self-closing medical clips
A method and apparatus for the endoscopic application of self-closing medical clips (3), in particular, for arresting internal bleeding. The distal end of a catheter tube (1) is introduced into the body of a living being to be treated. Several clips (3), arranged successively in the catheter tube (1), are pushed forward in the direction of the tube distal end by a user device located at the proximal end of the catheter tube (1). The foremost clip (3) to be applied is pushed out of the distal end and opened by an actuation device. The actuation device includes an actuation element (21) which can be actuated by the user device, moved longitudinally into the catheter tube (1), and acts on the first front clip (3), as well as a control part (25) which converts the actuation force of the actuation element into an opening movement of the legs (5) of the clip (3). After the opening of the clip (3), the actuation element (21) is separated from the clip (3), for releasing the clip to close its legs (5) for application, and to functionally link with the following clip (3) in the catheter tube (1).
US07740636B2 Multi-action device for inserting an intraocular lens into an eye
A device for inserting an intraocular lens (IOL) into an eye includes a tubular body member with an inner surface and a plunger with an gripping device that is receivable within the body member. The gripping device includes a locking member and is configured such that when urged longitudinally in a distal direction, the gripping device is movable in the distal direction within the body member. However, when urged longitudinally in a proximal direction, the gripping device is prevented from moving in the proximal direction by the locking member engaging with the inner surface of the body member. As such, inadvertent movement of the plunger in the proximal direction caused by pulling back on the plunger is substantially prevented. If proximal movement of the plunger is desired, then the plunger may include handle that is operatively coupled to the gripping device such rotation of the handle causes the handle to move longitudinally in the body member. Accordingly, the plunger may be advanced or moved distally by longitudinally pushing the handle and/or by rotating the handle.
US07740632B2 Vibratory syringe apparatus and in vivo delivery method
An apparatus and a method configured for the efficient delivery of a viscous material, such as bone cement, to a surgical site are described. A housing removably receives a large gauge syringe which is filled with the viscous material. The apparatus is a syringe-type assembly that uses at least one vibrating motor together with a plunger rod assembly. The method employs the continuous application of vibrational forces to the central barrel portion of the apparatus during the time that the viscous material is being delivered and/or applied in vivo. The vibration to the central barrel portion increases the tendency of the viscous material to flow thereby making delivery of such materials easier and more efficient.
US07740630B2 Anterior cervical plate system having vertebral body engaging anchors and connecting plate
An anterior cervical plating system includes vertebral body engaging anchors coupled to a connecting plate in moveable relationship to vary the spacing between the anchoring points of the plating system to the vertebral bodies and to allow and/or cause intersegmental compression of vertebral bodies. The plating system includes instrumentation and method for installation thereof. The plating system is capable of both passive and active dynamization and the ability to produce the former from the latter.
US07740627B2 Surgical method and apparatus for treating atrial fibrillation
The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.
US07740625B2 Surgical digitizing apparatus and method
A surgical digitizing apparatus and procedure will typically involve a pad having discrete segments which may be arranged in a specific order to accommodate a particular procedure. The individual segments can then be used to accomplish both diagnostic and therapeutic functions. For example, the segments can be interrogated to produce a map of body tissue and then electrosurgically energized to perform a therapeutic function in accordance with the map. Communication with the discrete segments will typically be accomplished through a microprocessor and associated switching circuits.
US07740624B2 Method for treating obesity by extracting food
To treat obesity, a tube is positioned that passes through a patient's abdominal wall into the upper digestive system of the patient. The patient is allowed to carry out his/her everyday affairs including ingesting food. After the patient has ingested food, the food is extracted by pumping it out of the upper digestive system through the tube. This approach is less invasive than current surgical procedures for reducing weight and allows patients to live a normal and active lifestyle without experiencing adverse side effects.
US07740622B2 Elastomeric gloves and methods of making
Elastomeric film-like products such as natural latex gloves are coated with novel lubricity compositions and compositions which protect the skin of the wearer from certain undesirable medical conditions. In powder-coated gloves, the coating composition comprises rice starch, and optionally USP-grade colloidal oatmeal in pharmaceutically accepted concentration. In powder-free gloves, the coating composition comprises colloidal oatmeal enhanced water or beta glucan solution, optionally in combination with one or more other starch components. Colloidal oatmeal enhanced water, and methods of making the colloidal oatmeal enhanced water are also disclosed. In addition, beta glucan solution, and methods of making the beta glucan solution are also disclosed. A liquid referred to herein as Polycoat may also be made by mixing colloidal oatmeal enhanced water with beta glucan solution, and the resulting liquid may be applied to elastomeric articles such as gloves.
US07740621B2 Medical needle and medical device
One of the aspects of the present invention is to provide a medical needle extending along a predetermined direction and having a vertical cross-section taken along a plane perpendicular to the predetermined direction of which cross-sectional area varies based upon a distance from a needle tip. The medical needle includes a plurality of maximal points where the cross-sectional area of the vertical cross-section is locally maximal, and a plurality of minimal points where the cross-sectional area of the vertical cross-section is locally minimal. The vertical cross-section at the maximal point closest to the needle tip has the cross-sectional area not less than those at any other maximal points.
US07740619B2 Spring driven ophthalmic injection device with safety actuator lockout feature
An ophthalmic injection device includes a dispensing chamber housing with an inner surface that partially defines a dispensing chamber for holding a substance, a plunger fluidly sealed to the interior surface of the dispensing chamber housing, and a needle fluidly coupled to the dispensing chamber. A temperature control device partially surrounds the dispensing chamber housing and alters a temperature of the substance. A piston is coupled to the plunger at one end and to a spring at the other end. The spring provides a force to drive the piston and the plunger. An actuator is coupled to the lockout bar with which a button is configured to interface. The actuator moves the lockout bar when the substance reaches a temperature, thereby allowing the button to be activated so that the spring provides the force to drive the plunger. An incorporated stop whose measurements may vary allow the expelled dosage to vary accordingly.
US07740618B2 Syringe device
A ratchet-free and gear-free one-to-one mechanism for setting a dose in a syringe device comprising a dose setting member adapted to be rotated along a piston rod with a threaded outer surface so as to set a dose to be ejected.During dose setting the piston rod is locked such that rotational movement of the dose setting member does not result in rotational movement of the piston rod.During dose ejection the piston rod and the dose setting member are locked in relation to each other such that translational movement of the dose setting member causes relative rotational and translational movement of the piston rod.
US07740615B2 IV catheter introducer with retractable needle—continuation
An IV catheter introducer having a retractable needle holder and a tubular plunger that are held by a detent structure in a preferred positional relationship prior to and during insertion of the catheter. Following insertion, the plunger is pushed past the detent structure, permitting a compressed spring to force the needle holder upwardly into the plunger. A vented end cap in the plunger permits rapid venting of air displaced during retraction of the needle holder. The needle holder includes a flash chamber that is easily viewable through a clear plastic housing. Wings are provided on the housing to facilitate one-handed operation of the device. A method for assembling the subject catheter introducer is also disclosed.
US07740614B2 Indwelling needle assembly
An indwelling needle assembly has an inner needle having a sharp point at its tip, an inner needle hub fixed to a base section of the inner needle, a hollow outer needle into which the inner needle is inserted, an outer needle hub fixed to a base section of the outer needle, and a tube inserted into the inner needle hub and connected to the base section of the outer needle hub such that the inner cavity of the tube communicates with the inner cavity of the outer needle. The center axis of the outer needle and the center axis of the tube at its head section are substantially parallel with each other with the inner needle inserted into the outer needle.
US07740613B2 Inserter for automatically inserting a cannula of an indwelling member of an infusion device
An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.
US07740610B2 Single-use syringe
An operable single-use syringe includes a barrel having an inside surface defining a chamber for retaining fluid and an open proximal end. A plunger rod having an elongate body portion and a stopper at its distal end slidably positioned in fluid-tight engagement in the barrel. A locking element is positioned in the barrel between the plunger rod and the inside surface of the barrel. The locking element has a base and two leg members projecting therefrom that are positioned in longitudinal grooves in the plunger rod. The locking element only moves distally in the barrel and prevents re-use of the syringe after its contents have been discharged.
US07740606B2 Method and apparatus for automated optimization of treatment plans
A method of adjusting infusion parameters that provide coverage of a selected target volume for direct infusions of a fluid includes using an algorithm for calculation of optimal packing of spheres or cylinders in a selected volume to determine the coverage of the selected target volume.
US07740605B2 Power-assisted liposuction instrument with cauterizing cannula assembly
An apparatus is disclosed for mechanically-assisted liposuction treatment. The apparatus includes a hand-holdable housing, an electro-cauterizing cannula assembly, and a reciprocation mechanism. The hand-holdable housing has a cavity adaptable for receipt of a portion of the electro-cauterizing cannula assembly. The electro-cauterizing cannula assembly has a distal end and a proximal end and at least one aspiration aperture about the distal end. The reciprocation mechanism is disposed within the housing and is operably associated with either the cannula so that the cannulas can be selectively caused to reciprocate relative to the housing. As the cannula is caused to reciprocate relative to the housing, the aspiration aperture formed through the distal end of the cannula assembly is caused to undergo periodic displacement. The cannula assembly is releasably detachable from the hand-holdable housing to facilitate cleaning and sterilization of the cannula assembly and the housing.
US07740604B2 Ocular implants for placement in schlemm's canal
An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
US07740599B2 Magazine for annulary capillary lancets
A device for receiving a body fluid for analysis, comprising a container and at least one sample-receiving unit which can be impinged upon by the body fluid at a receiving point and which can be extracted from a guide chamber of the container by means of a drive unit. According to the invention, a coupling device is provided in order to couple the sample receiving unit to the drive unit to ensure back and forth movement between the guide chamber and the receiving point.
US07740594B2 Cutter for biopsy device
A biopsy device and method are provided for obtaining tissue samples. The biopsy device can include a probe assembly having a cannula and a cutter assembly. The cutter assembly includes a hollow cutter, and the hollow cutter can be removed from the probe assembly without disassembling the probe assembly. The method can include the steps of positioning the tissue receiving port in the tissue to be sampled; removing the cutter from the biopsy device; imaging the biopsy site associated with the tissue receiving port of the biopsy device after removing the cutter from the biopsy device; inserting the cutter into the biopsy device; and severing tissue received in the tissue receiving port with the cutter.
US07740584B2 Method and system for mapping physiology information onto ultrasound-based anatomic structure
A physiology system is provided that includes an ultrasound beamformer that is configured to receive signals from an ultrasound probe that is located proximate the region of interest. The system includes an ultrasound processor module for generating an ultrasound image, based on the ultrasound data, that is representative of an anatomical structure of a portion of the region of interest contained in the scan plane. A physiology signal processor module is also provided and configured to receive physiology signals from a catheter located proximate the region of interest. The physiology signal processor module produces physiology data representative of the physiology activity of the portion of the region of interest contained in the scan plane. A display processor module forms a display image combining the ultrasound image and physiology data.
US07740583B2 Time delay estimation method and system for use in ultrasound imaging
A method for correcting a time delay between at least two signals in ultrasound systems is provided. The ultrasound system comprises a beamformer processor comprising a summer coupled to the transducer array and configured for performing a complex operation on a first plurality of receive signals to generate a beamsum signal; wherein each of the receive signals comprise a corresponding beamforming delay and a complex filter coupled to the summer and configured to transform the beamsum signal to an analytical signal. The beamformer processor further comprises a plurality of correlator processors coupled to at least one respective transducer element and the complex filter, each correlator processor configured to calculate a correlation sum for at least one receive signal and at least one time delay estimator adapted to receive the correlation sum of at least one receive signal and configured to estimate the corresponding time delay using the correlation sum.
US07740579B2 Otoscope with internal printer
An otoscope 800 includes a lens 802 and an eyepiece 801 by which a doctor can examine the external ear cavity of a patient. The otoscope includes a handle 803 within which there is situated a printer to provide an instantaneous permanent record of an image viewed by the doctor. Upon activation of a trigger 817, a permanent graphic image is printed onto a sheet 816 that passes out of the handle 803 via slot 804.
US07740573B2 Dunnage conversion machine with floating guides
A dunnage conversion machine (115), wherein sheet stock material is crumpled to form a crumpled strip, includes a feeding assembly (132). The feeding assembly (132) includes opposed feeding members that engage and advance the crumpled strip therebetween. One of the feeding members (141) includes a rotating member (141) supported on a shaft (144) for rotation about the axis of the shaft, the shaft being mounted for transverse movement toward and away from the other feeding member (140) to accommodate variations of the thickness of the crumpled strip as it is advanced between the opposed feeding members (140 and 141). The conversion machine (115) also includes a guide member (200) positioned laterally adjacent to the rotating member (141) progressively to guide a portion of the crumpled strip underneath the shaft (144). The guide member (200) has at least a portion adjacent the shaft (144) that is transversely movable.
US07740569B2 Weight-lifting apparatus and method of assembling same
A fixed weight/permanent weight-lifting apparatus including dumbbells and barbells is provided including an elongated shaft having threaded ends, a centrally located handle, collars distal the threaded ends and tapered splines between the threaded ends and the collar and a head to provide the fixed weight of the apparatus that has been forced onto each end of the elongated shaft and a nut securely fastened on each of the threaded ends. When the nut is tightened onto each end with sufficient torque, the tapered spline is forced into the head and forms grooves in the head that correspond to ridges in the spline, which has a higher tensile strength than that of the head.
US07740563B2 Elliptical exercise machine with integrated anaerobic exercise system
A combined anaerobic and aerobic exercise system comprises a multi-part frame, for example a telescoping frame, or a pivoting frame. The aerobic system may include an elliptical exercise device, while the anaerobic system may include a cable-based system wherein resistance is adjustable. An electronic console system at the exercise system allows a user to view progress in both anaerobic and aerobic workouts, and to send input signals that adjust anaerobic and aerobic resistance mechanisms.
US07740561B2 Hand exercising device
An exercising device for the hand is disclosed. A securement is secured to an anchoring member comprising a band with a pair of ends configured to extend around and be secured to the hand of the user and configured to support the anchoring member in a position overlying the palm of the hand of a user and is coupled to the hand of the user. A plurality of fingertip engaging members are each configured and dimensioned to be secured to a respective fingertip a plurality of fingertip anchorings. Each of the fingertip anchorings is secured to a respective fingertip engaging member. A plurality of respective palm anchorings are secured to the anchoring member. A plurality of respective elastic members each have first and second ends. The first end of each of the elastic members is secured to the fingertip anchorings. The second end of each of the elastic members is secured to the palm anchorings. Alternatively, the securement and the anchoring member comprise a closed loop elastic strap.
US07740558B2 Automatic transmission, control apparatus and control method for the same
A transmission control unit predicts a next gear position when a predetermined gear position is achieved. In accordance with a result of the prediction, the transmission control unit operates a predetermined synchromesh to execute a standby control (pre-shift control). In the standby control, a transmission input shaft connected to a friction transfer mechanism not used for achieving a current gear position and a transmission output shaft are connected to each other via a predetermined gear train, and made standby. The transmission control unit makes different from each other an engagement load of the synchromesh when a connection of the synchromesh is done in accordance with the prediction result and an engagement load of the synchromesh when a connection of the synchromesh is done in accordance with the other condition different from the prediction result.
US07740555B2 Sprocket tooth profile for a roller or bush chain
An improved sprocket profile for engaging a roller or bush chain smoothly and preventing radial impact with the root of the tooth during engagement. Contact between the sprocket teeth and the roller chain is altered by providing teeth with a root radius equivalent to that of the chain engaging component, with the center point of the root radius located one chordal distance inside the sprocket's pitch circle. This profile allows chain rollers or bushings to impact sprocket teeth tangentially on their flanks rather than radially on their tooth root.
US07740548B2 Basketball training apparatus
The present invention relates to the sports training aids, in particular a improved apparatus for providing drills for new basketball players to practice rebounding skills, not having a platform or base below the players as they jump which can twist an ankle or knee. Further an improved mechanism for tuning the action in the recoil assembly is provided.
US07740546B2 Golf ball
The invention provides a golf ball having a ball component made of a material molded under heat from a rubber composition of (a) a base rubber which includes a polybutadiene of at least 40% cis-1,4 structure, (b) an unsaturated carboxylic acid and/or a metal salt thereof, (c) an organic peroxide, and (d) a halogenated thiophenol, and/or a metal salt thereof, which is prepared by reacting starting materials in a polar solvent then washing with water and drying. The golf ball of the invention uses as a ball component a material of exceptional resilience which is obtained by molding a rubber composition under applied heat. As a result, the ball as a whole has an excellent rebound.
US07740545B2 Curved golf putter
A golf putter with a having a curved body and a high toe design is disclosed and claimed. The putter head includes a face member, which has a heel and a toe, and a body member. The body member is connected to and extends rearward from the face member. At least a portion of the body member is curved toward the heel of the club head. The face member preferably is angled such that the toe has a greater height than the heel. The body member may be similarly angled. The body member extends through the face member and forms at least a portion of a striking face of the club head.
US07740543B2 Pneumatically powered billiard cue stick
Various embodiments of a pneumatically powered cue stick are disclosed. Both embodiments employ the use of compressed gas to derive the full range of power necessary to engage in the various games of pool and billiards, including the break shot, without the need for modification of surface area of the game table. The preferred embodiment is adaptable to existing forms of metering, triggering, portable compressed gas dispensing devices such as, but not limited to, paintball marker guns. An alternative embodiment integrates the metering, triggering, and gas dispensing components of the adaptable type, eliminating the need for the separate, adaptable devices previously mentioned. Both embodiments incorporate a cylinder assembly 14 and a cue stick rod 12 threadably, or otherwise attached, slidably mounted within a support casement 10, to facilitate a predetermined length not unlike, but not limited to, that of a conventional cue stick. Both embodiments are suitable for one-handed operation.
US07740542B2 Water amusement method
A water transportation system and method are described, generally related to water amusement attractions and rides. Further, the disclosure generally relates to water-powered rides and to a system and method in which participants may be actively involved in a water attraction. This transportation system comprises at least two water stations and at least one water channel connecting the at least two water stations for the purpose of conveying participants between the at least two water stations. In addition, the water transportation system may include conveyor belt systems and water locks configured to convey participants from a first source of water to a second source of water which may or may not be at a different elevation.
US07740540B2 Gaming machine
A gaming machine, having a display unit that displays a game image for use in a game, including: an image data storage unit that stores common image data that is common to user countries in which the gaming machine is used and individual image data that differ from user country to user country; and a position changing unit that changes the display position of the game image displayed on the display unit, on a per user country basis, using the common image data and the individual image data, stored in the image data storage unit.
US07740532B2 Recording medium storing game progress control program, game progress control program, game progress control method and game device each defining a key set having correspondence to game display areas each having plural sections
A key reception processing unit 203 receives a key-designated area designated by means of a tenkey 211, a timing detector 205 detects a timing at which the key-designated area was received, a meet section detector 204 detects a meet section where the center position of a ball object 402 displayed to move on a display screen of a monitor 22 passes, and a game progress processing unit 206 proceeds a game in accordance with a batting result obtained by combining a batting result corresponded beforehand to the detected timing and a batting result corresponded beforehand to the detected meet section.
US07740525B2 Device for securing material plates, such as glass sheets, during the working thereof
A device for working of material plates (1), such as glass panes, has a supporting member (25, 26, 29) for the material plate (1) and a tool (12, 18) for working the material plates (1). The supporting member (25, 26, 29) has paired supporting elements (25′, 25″, 26′, 26″, 29′, 29″) with supporting surfaces (27′, 27″, 30′, 30″) facing one another, between which the material plate (1) is held. There are openings (31) for liquid emerging under pressure in the supporting surfaces (27′, 27″, 30′, 30″). The material plate (1), especially the glass pane, is therefore not mechanically supported, as is conventional in the prior art, but uses a liquid film which is formed under pressure in the gap between the material plate (1) and the supporting surfaces (27′, 27″, 30′, 30″) of the supporting elements (25′, 25″, 26′, 26″, 29′, 29″).
US07740524B2 Drywall corner sanding tool
A sanding tool for sanding drywall corner joints is provided. The tool has an elongated mounting plate with a swivel handle attached to one side, and to the other side is attached one or more circular sanding disk holders to which disks of sanding medium are removably attached to a flat face of the sanding disk holder. The sanding disk holders are rotatably mounted on short axles attached to the mounting plate, and are each configured having a relatively wide edge that frictionally engages a wall adjacent the wall being sanded. This causes the sanding disk holder to rotate, sanding the drywall joint with a rotary motion instead of a linear motion.
US07740523B2 Portable power tool with a guide channel
A portable power tool has at least one housing part (10) and a guide channel (12) for carrying chips and/or abrasive particles away from a working area (14). At least one wall region (16) of the guide channel (12) is movable relative to the housing part (10) for cleaning purposes.
US07740522B2 Knife sharpener
A motorized knife sharpener includes means of for sharpening heavy, medium, and fine blades at angles appropriate to the cutting edges of such blades.
US07740511B2 Electrical contact and electrical connector using the same
A contact having a support, a first arm supported by the support and configured to contact a mating contact, and a second arm facing the first arm in a facing direction and supported by the support and configured to contact the mating contact is disclosed. A first spring and a second spring are each connected to the support and bent in the facing direction and extend along a plane substantially perpendicular to the facing direction. The first spring and the second spring elastically support the support in the facing direction and a mount is connected to the first spring and the second spring.
US07740510B2 Electrode clamp
An electrode clamp (10; 100) for making contact with a film electrode and a snap electrode has a first part (12; 112), a second part (14; 114), and a contact element (60; 160). For clamping a film electrode, the two parts (12, 14; 112, 114) can be pivoted toward one another. In an initial state of the electrode clamp (10; 100), the first part (12; 112) and the second part (14; 114) have an offset (36; 136) relative to one another. The offset can be reduced by movement of the second part (14; 114) relative to the first part (12; 112) to such an extent that the snap electrode can be inserted into the electrode clamp. By a reset motion of the second part (14; 114) relative to the first part (12; 112) in the direction of the initial state, the snap electrode can be clamped against the contact element (60; 160) and contact can be made with the snap electrode. The electrode clamp (10; 100) can be connected in a mechanically detachable manner to the snap electrode.
US07740508B2 Probe block assembly
A probe block assembly includes a block and a cable terminated to a coaxial connector that is configured to electrically communicate with a plurality of probes inserted in the block. The coaxial connector includes a connector signal contact configured to separably connect to a first probe that is insertable into an aperture of the block and insulated from the block, and a resilient ground beam configured to commonly ground one or more second probes inserted in the block.
US07740506B2 Adapter and consumer electronic device functional unit
A functional unit of a video display, a main body and a connector associated with the main body for receiving an external electrical signal that is transmitted to the video display. The main body provides a first service to connect the video display to the host, a second service to support the functional unit on a generally horizontal surface, and a communication function in addition to the function provided by the video display.
US07740502B2 Reuseable coaxial connectors and related methods
Coaxial connectors include a connector body and an inner contact post. A compression sleeve is also provided that is configured to impart a generally circumferential compressive force to secure one or more elements of a coaxial cable between the connector body and the inner contact post when the compression sleeve is in a seated position. The compression sleeve or the connector body includes a first disengagement mechanism that is configured to assist moving the compression sleeve from the seated position to an unseated position in which at least some of the circumferential compressive force is eliminated.
US07740497B2 Electrical connection system
An electrical connection system for providing electrical connection between first and second devices comprises one or more electrical connection posts and one or more electrical connection tubes. Each post has a first end and an opposite second end, where the first end is configured to electrically connect with a first device such as a photovoltaic cell. Each tube has an opening to receive and provide electrical connection with the second end of a respective post. First and second end connectors are provided at respective opposite axial ends of a connection tube to enable end to end electrical connection between adjacent tubes. The opening comprises a longitudinal slot together with a plurality of secondary slots. Each secondary slot comprises a first length that extends in a circumferential direction, and a second length that extends in the axial direction, with a circular portion that acts as an electrical contact. In order to connect the posts to a tube the tube is orientated so that the ends of the posts are in alignment with the slot. The tube is then slid axially so that the ends of the post are located within the slot and inside the tube adjacent respective first lengths of a slot. The tube is then rotated about its longitudinal axis and then slid axially so as to finally locate the ends within the circular portions.
US07740491B2 Card connector
A card connector includes a housing which allows a card to inserted thereinto, and a plurality of terminal members which is arranged in the housing, and is respectively connectable to a plurality of external connections provided on the bottom face of the card. The plurality of terminal members is composed of first terminal members which are arranged on an inner bottom face of the housing, are provided side to side along an insertion direction of the card, and are connectable to first external connections of the plurality of external connections of the card which are provided on the side of a rear end of the card, and second terminal members which are connectable to second external connections of the plurality of external connections of the card which are provided on the side of a front end of the card. The card connector also includes a driving member which is able to displace the first terminal members which are provided on the inner bottom face of the housing, and located nearer to an insertion slot of the card when the card is inserted in a direction apart from the second external connections of the card. The driving member is provided with a grounding portion which is located nearer to the insertion slot of the card than the first terminal members.
US07740487B2 Connector and manufacturing method thereof
A connector and a method of manufacturing the same one are provided. The connector includes an insulating casing and a plurality of terminals. The insulating casing has a joining surface and a plurality of terminal holes. The terminal holes are arranged to pass through the joining surface in a manner to slant relative to the insulating casing. Each terminal hole has a pair of opposite inner walls. The insulating casing further has a plurality of positioning parts adjacent to at least one of the respective inner walls of the respective terminal holes. The terminals are located within the respective terminal holes. With the use of the positioning parts, when the terminal holes of the insulating casing is formed, the pins do not tend to break and then the slant terminal holes are smoothly formed.
US07740485B1 Electric power interrupt control
An apparatus, when in use, is connected to standby electrical power through a power cord. The apparatus controls the electrical power source to a transportation vehicle with an electrical control device. The electrical control device is energized by a switch. The switch is operated by attaching the transportation vehicle power cord by means of compression via two nylon ties. When tension is present on the transportation vehicle power cord the nylon ties will break. When the nylon ties break, the switch immediately de-energizes the electrical control device and the transportation vehicle power cord. If the transportation vehicle continues to pull on the transportation vehicle power cord, it will be in the de-energized mode. The transportation vehicle power cord will be pulled away from the apparatus and away from the electrical connections through a water tight grip.
US07740478B2 Applicator for dental compounds
An applicator for dental compounds includes a shaft, the front end of which can be connected with the aid of a fastening device to a syringe containing the dental compound, and a plunger. The shaft contains a ram for advancing the plunger. The fastening device has an inner sleeve, attached to the shaft, and an outer sleeve, attached on the inner sleeve rotatably with respect to it. The inner sleeve is substantially cylindrical and has such a cavity that its cross section is substantially U-shaped. Clamping takes place as a result of eccentricity.
US07740469B2 Method and apparatus for uniformly stretching thermoplastic film and products produced thereby
Thermoplastic films and laminates are made by extrusion and stretching using differential speed rollers employing a short stretching gap of no more than one inch immediately after the extruded film product is formed. The method and apparatus control the thickness of the stretched film and impart desirable mechanical properties thereto such as film products with a high modulus for handling and suitable tensile for softness.
US07740465B2 Casting mold for producing an optical semiconductor module
A method and a casting mold for producing an optical semiconductor module is provided, wherein a semiconductor body having at least one optically active element on its top is introduced into a leadframe. Then conductive connections are established between the semiconductor body and the leadframe, and then the leadframe and semiconductor body are encapsulated in a casting mold. Wherein provided in the part of the casting mold that faces the top of the semiconductor body are masking bodies, which extend from the top inner wall of the casting mold towards the optically active elements and cover the elements with their respective end face in a way that seals out casting material.
US07740464B2 Device for post-treating tyres
The invention relates to a device comprising a receiving device (3) for post-treating tires (1). After vulcanizing the elastomer material, the tires (1) are subjected to internal pressure by means of support gas, and cooled. Said receiving device (3) is embodied such that it can maintain the tires (1) and also seal the inner chamber of the tires. Also, a pressurized gas supply is connected to the receiving device (3). Said receiving device (3) comprises at least two fixed receiving areas (4) for at least two tires (1). The tires undergo at least one introduction process using a positionable handling device (19).
US07740462B2 Tire vulcanizer
The invention provides a tire vulcanizer having a vulcanizer body and a shaping unit and configured to be able to accurately mount a green tire in the shaping unit and shape it accurately when shaping the green tire in the shaping unit. As a result, the green tire can be placed and set accurately in a lower container of the vulcanizer body when the shaping unit is placed in a container of the vulcanizer body. In order to mount the green tire in the shaping unit (B) outside the vulcanizer body, the tire vulcanizer includes outside the vulcanizer body (A) a tire mounting device (D) which mounts the green tire in the shaping unit.
US07740461B2 Apparatus and method for manufacturing polymeric fibrils
An electrospinning apparatus is described. The electrospinning apparatus has a rotary nozzle mechanism that moves simultaneously along a non-linear track for forming polymeric fibrils, so that the polymeric fibrils can be piled to form a uniform web on a receiving carrier from any receiving angle. Therefore, the electrospinning apparatus resolves problems of the prior polymeric fibrils, such as various distribution and slow production rate. In addition, a method of manufacturing polymeric fibrils in the aforementioned electrospinning apparatus is further described.
US07740453B2 Multi-segment wind turbine blade and method for assembling the same
A multi-segment wind turbine blade comprises at least two blade segments. A first spar cap segment is attached to a first blade segment and a second spar cap segment is attached to a second blade segment. The first and second spar cap segments are configured to form a scarf joint. First and second spar cap brackets are attached in locations of the first and second spar cap segments, respectively, selected to facilitate alignment of the first and second spar cap segments at the scarf joint. At a field site, the first and second spar cap segments are bonded after fastening the first and second spar cap brackets.
US07740451B2 Turbomachine blade
The blades of a turbomachine comprise airfoils, which are bent such that the lean angle (φ), defined as the angle which the stacking line of the airfoil includes with the radial direction, and measured in the direction of rotation (ω), is variable along the width of the flow channel and decreases from the hub towards the housing.
US07740449B1 Process for adjusting a flow capacity of an airfoil
A process for adjusting a throat area (the flow capacity) between airfoils in an airfoil configuration such as a stator ring used in a small gas turbine engine. The airfoils are designed with an over-extending trailing edge forming a throat area sized such that a worst case tolerances design flow area would be achieved. A fluid with a flow rate representing the actual fluid for normal operation in the airfoil configuration is passed through the airfoil throats and the flow rate is measured. A specified portion of the leading edge of each airfoil is removed until the design flow rate through the airfoil configuration is achieved. A plurality of iterations of measuring flow rates and removing trailing edge material is performed until the design flow rate is achieved.
US07740446B2 Serial fan with a plurality of rotor vanes
A serial fan includes a frame, a plurality of rotor vanes, a support connected to the frame through a plurality of connecting parts. The plurality of rotor vanes are arranged in series in the frame along an axial direction and the plurality of connecting parts are disposed therebetween to minimize space occupied by the serial fan in the axial direction, and effectively increase the blast pressure.
US07740444B2 Methods and system for cooling integral turbine shround assemblies
A method for cooling a turbine shroud assembly includes providing a turbine shroud assembly including a shroud segment having a leading edge, a trailing edge and a midsection defined therebetween. A shroud support circumferentially spans and supports the shroud segment. The shroud support includes a forward hanger coupled to the leading edge, a midsection hanger coupled to the midsection and an aft hanger coupled to the trailing edge. An annular shroud ring structure includes a midsection position control ring coupled to the midsection hanger and an aft position control ring coupled to the aft hanger. Cooling air is extracted from a compressor positioned upstream of the turbine shroud assembly. Cooling air is metered through the shroud support directly into only at least one active convection cooling zone defined between the shroud segment and the shroud support while substantially preventing cooling air from entering an inactive convection cooling zone positioned radially outwardly from the at least one active convection cooling zone and defined between the shroud support and the shroud ring structure and between the midsection position control ring and the aft position control ring.
US07740443B2 Transpiration clearance control turbine
A row of turbine blades is surrounded by a turbine shroud. The shroud is supported by a turbine case having a pair of radially outwardly extending rails. The rails are perforate for channeling therethrough control air to control thermal radial movement of the case, and in turn radial position of the shroud supported therefrom.
US07740434B2 Fastener
There is provided a fastener able to prevent damage due to environmental factors such as ultraviolet rays, and impact from sanddust, lumps of ice, and raindrops without obstructing a flow of electric shock current that flows along a top surface of an outer skin. The fastener connects an outer skin of an aircraft to a structural member positioned inside this outer skin, and is provided with a dielectric layer arranged to cover one end surface of a head section, and a conductive layer arranged to cover one end surface of this dielectric layer.
US07740430B2 Support assembly for use with truck bed
A support assembly for use with truck bed comprises first mounting frame 5, second mounting frame 6, first horizontal arm portion 11, first vertical arm portion 12, first arm mounting holes 13, second horizontal arm portion 21, second vertical arm portion 22, first mounting end 24 of second vertical arm portion, distal, open end 25 of second horizontal arm portion, first support bracket 30, first vertical sleeve 40, second support bracket 50, second vertical sleeve 60, first brace 70, second brace 90, outer sleeve 100, first hitch pin assembly 110, and second hitch pin assembly 120.
US07740428B2 Rotor
A rotor, used particularly in a rotating tool for machining workpieces, includes a rotor base body with locations, which are formed on the periphery thereof in an interspaced manner and which are suited for fitting the rotor with functional elements. The rotor base body includes a first, radially outer base body element and a second, radially inner base body element. When the rotor is not rotating, a jointing pressure prevails along an encircling joining line, which is formed between both base body elements. The second, radially inner base body element has a higher modulus of elasticity than that of the first, radially outer base body element.
US07740426B2 Deep-hole drill having back-tapered web
A drill having a web which is provided by a central portion of a cylindrical main body of the drill and which includes a back-tapered portion and a constant-thickness portion. The cylindrical main body has a large diameter portion and a small diameter portion contiguous to the large diameter portion, such that a step is provided between the large and small diameter portions. The large diameter portion provided by the axially distal end portion of the cylindrical main body has an axial length which is larger than an axial length of the back tapered portion of the web provided by the axially distal end portion of the web, such that a boundary between the back-tapered portion and the constant-thickness portion of the web is located in the large diameter portion of the cylindrical main body.
US07740423B2 Vacuum modulating air control valve apparatus
A vacuum modulating air control valve includes a valve body with air intake ports, an output port, and a valve throat. A valve member is slidably mounted within the valve body between open positions relative to the valve throat and a closed position, to which the valve member is urged by a valve spring. A pneumatic cylinder has a piston forming a vacuum chamber and has a piston rod connected to the valve member. The output port is connected to a feedpoint of a vacuum conveying system, and the vacuum chamber is connected to a vacuum line communicating with the vacuum conveying system. A vacuum level within the vacuum chamber retracts the valve member from the throat, thereby admitting ambient air into the vacuum conveying system to control a material-to-air ratio within the system.
US07740422B2 Method for producing large surface area geogrids with high tensile strength and large surface area geogrids
The invention provides large surface area geogrids with a high tensile strength, a method and apparatus for producing them, and their use as drain and reinforcement grids and as fences. The method for the continuous production of geogrids which have a large surface area and comprise thermoplastic bars which cross one another and are joined together by welding at the areas where they cross one another is characterized in that single-layer, homogeneous, molecular-oriented plastic bars with a high tensile strength are used and a multiplicity of crossing areas arranged behind one another and next to one another are intermittently welded simultaneously using the vibration-welding technique. In this method, a newly developed vibration-welding apparatus is used, which is characterized in that it has at least one vibration device which can be used to weld at least 100 crossing areas, preferably up to 500 crossing areas, simultaneously.
US07740419B2 Method for improving soft ground
A method of improving soft ground, capable of effectively restricting settlement of a peripheral part of ground to be improved involved in improvement of the soft ground. A vertical supply path is formed by placing a vertical drain material in ground in the periphery of ground to be improved, and water containing a water stop material is charged in the vertical supply path to supply the water containing the water stop material to the ground through the vertical supply path. Then the water stop material charged in the vertical supply path follows a water flow and spreads in the periphery of the vertical supply path to form a water stop zone. The water stop zone formed by the water stop material prevents the movement of ground water in the ground and restricts lowering of the ground water in the ground caused by forced drainage from ground to be improved, effectively restricting settlement of the ground involved in improvement of soft ground.
US07740417B2 Construction method for installing underground pipes for high-tension cables by using trough
A construction method for installing underground pipes for high-tension cables uses a trough. The method includes the steps of forming an excavation trench by excavating the ground, installing the trough on the bottom of the excavation trench, pouring sand into the space section, placing the underground pipes on the sand, pouring again the sand onto the underground pipes, filling a gap formed between the trough and the excavation trench using sand and gravel, forming an upper protecting member on the trough, and performing surface treatment by using road pavement materials.
US07740416B2 Tamper device with replaceable tool head assembly
A hand or mechanically powered tamper tool which has a removeable, replaceable, tool head assembly. The tool head assembly is a separable component from the upper section of the tamper tool which consists of the mounting plate and its attached tamper handle. The tool head assembly has a rubber or similarly resilient material pad bonded to the underside of a backing plate. Connection elements, such as bolts, are permanently secured between the pad and the backing plate. The bolts extend through and are upstanding from the backing plate. The bolts are configured to then extend through openings in the tamper mounting plate, where nuts are used to secure the tool head assembly to the mounting plate. The tool head assembly is thus removeable from the mounting plate and its handle or supporting element and allows for the simple and ready replacement of a used and worn tool head assembly with a new tool head assembly.
US07740415B1 Manhole cutting and removing device
A device to secure, cut and sequentially remove a manhole from a street environment. The manhole removing device is supported and rotatably driven hydraulically by a mobile operation equipment. A circular disk assembly has adjustable pavement cutters adjustably positioned from there within inter-related manhole centering and a locking alignment and engagement plate assembly define a one-step cutting and removal of an existing manhole from the street for replacement.
US07740408B2 Coupling device, auxiliary device and adaptor fixing member
A coupling device for coupling optical fiber cables facilitates positioning in a circumferential direction for coupling a connector. When a connector fixing member is inserted into an adaptor fixing member, a protruding section of the connector fixing member slides along an end surface of the adaptor fixing member, and is automatically guided to a notched section.
US07740406B2 Linear motion guide system with highly-tight sealing units
A linear motion guide system is disclosed in which a clearance between a slider and a guide rail is closed truly to clear foreign matter away from entering inside the system through any end of the slider traveling on the guide rail. Thus, the linear motion guide system is befitting to severe working environment where much foreign matter occurs. A highly-tight sealing unit is comprised of a cassette constituted with a front panel and an enclosure, sealing plates stowed into the cassette, lubrication plates each interposed between any two adjacent sealing plates, and a rear panel to close an open edge of the enclosure. The sealing plates are each composed of an intermediate spongy medium flanked by skin layers and impregnated with lubricant. The lubrication plates have pores filled with lubricant.
US07740405B2 Cassette
A cassette includes a main cassette body having a radiation detector for detecting radiation that has passed through a subject and converting the detected radiation into radiation image information, and a communication unit for wireless communications with a console. The communication unit is connected to the main cassette body by a cable and detachably mounted in a cradle part on said main cassette body.
US07740403B2 High-temperature sensor
The invention relates to a high-temperature sensor, which can be used at temperatures of at least 600° C. and comprises a metallic protective tube and a measuring resistance that is surrounded by a ceramic powder. The measuring resistance is connected to the electric cable by means of stress-relieved measuring resistance connecting wires and internal conductors. The latter are provided with a solid and/or flexible insulation consisting of a ceramic material. The measuring resistance and the internal conductors are arranged in a metallic protective tube, which narrows in the vicinity of the measuring resistance. The ceramic powder contains admixtures of oxygen-giving oxide compounds.
US07740402B2 Fluid detector
A detector and a method for determining the presence of a fluid are disclosed. The detector comprises a probe having a thermistor with the probe being arranged to be exposed to a fluid and to allow thermal flow between the thermistor and the fluid, a temperature sensor for measuring the temperature of the thermistor and a controller. The controller is arranged to supply electrical power to the thermistor when it is below a predetermined temperature to heat it up and to turn off the supply of electrical power to the thermistor when it is at or above the predetermined temperature. The presence or identity of a fluid exposed to the probe is determined based on the proportion of time that power is supplied to the thermistor to maintain it substantially at the predetermined temperature. The ambient temperature of the fluid to which the probe is exposed may also be measured and electrical power may be supplied to the thermistor to keep it substantially at a predetermined temperature above the measured ambient temperature.
US07740399B2 Dry chemical feeder for a chemical mixing system
A feeder system comprising a hopper for holding dry chemical. A feed tube extends from the hopper and is for delivering dry chemical to a mixing tank. A first solenoid actuator is provided for controlling the opening and closing of a first solenoid actuated gate that is disposed in the feed tube. A second solenoid actuator is provided for controlling the opening and closing of a downstream second solenoid actuated gate disposed in the feed tube. A central controller is provided that is in communication with and controls the system components including the introduction of the dry chemical and process water into the mixing tank. The central controller controls a metering pump that pumps chemical mixed solution out of the mixing tank.
US07740397B2 Culinary whisk
There is provided a culinary whisk comprising one or more wire loops for mixing foodstuffs, the or at least one of the wire loops includes an inner metallic wire portion and an outer polymeric portion enclosing the inner portion, wherein the inner portion is provided with groove(s) along substantially the length thereof for increasing frictional contact with the outer portion or means for fixedly adhering the outer portion to the inner wire portion whereby in use relative movement between the external portion and the internal portion is reduced.
US07740394B2 Backlight module having two optical sheets
A backlight includes a case, pluralities of light sources, pluralities of needles, pluralities of supporting portions, a first optical sheet, a second optical sheet, and pluralities of first microstructures. The light sources are disposed inside the case, the needles are disposed on the bottom surface of the case, and the supporting portions are disposed on the needles. The first optical sheet is supported on the top of the needles. The second optical sheet placed under the first optical sheet has pluralities of holes, and the needles penetrate the holes. The second optical sheet is supported on the supporting portions. The first microstructures are disposed on the first optical sheet or on the second optical sheet to provide a light condensing function.
US07740382B2 Light source module including light converging element
A light source assembly provides an illumination beam and the light converging element is disposed on a transmission path of the illumination beam. A light converging element has a top end and a bottom end opposite to the top end. The light converging element is gradually reduced from the bottom end to the top end. The top end is opposite to the light source assembly and has a cavity. The illumination beam is incident into the light converging element from the cavity and exits the light converging element from the bottom end.
US07740380B2 Solid state lighting apparatus utilizing axial thermal dissipation
A solid state lighting apparatus characterized by its compact, predominately axial form factor, utilizes an axial thermal transfer member constructed of Highly Oriented Pyrolytic Graphite (HOPG) to aid in the dissipation of waste heat generated during its operation. The lighting apparatus is chiefly comprised of a Light Emitting Diode (LED) die array and circuit structure assembly affixed to one end of the axial thermal transfer member and further includes a transversely mounted heat sink structure, running the length of, and being affixed to, opposite sides of the axial member. The axial member serves to distribute waste heat down its length, and simultaneously, into a transverse plane where the waste heat is dissipated into the transversely mounted heat sink structure. A fan may be utilized to evacuate the waste heat out of the lighting apparatus and into the ambient environment.
US07740378B2 Device and system for an optical element holder
A supporting structure is disclosed for both securing optical elements and for providing optimal cooling of the optical elements and the light source.
US07740377B1 Holiday tree ornament having smoke alarm
A holiday tree ornament that incorporates a number of internal lights along with a smoke alarm that is connected to a power source is disclosed. The holiday tree ornament includes an outer housing, which is hollow, and a cover that can be placed atop the housing. The outer housing is fabricated from a base and a plurality of walls, with the outer housing preferably having the shape of a star. Within the outer housing is located a plurality of lights that are connected via lengths of wiring. In addition, a smoke alarm is connected to the wiring. A number of air holes are located on the base to ensure free air flow from the outside air to the air within the holiday tree ornament. The lights and the smoke alarm are connected to a power source, which preferably is standard household current.
US07740374B2 Optical plate and backlight module using the same
An exemplary optical plate includes one or more transparent plate unit. The transparent plate unit includes a light output surface, a bottom surface, a plurality of spherical depressions, a plurality of enclosing V-shaped protrusions, and one or more lamp-receiving portion. The light output surface is opposite to the bottom surface. The spherical depressions are formed on the light output surface. The enclosing V-shaped protrusions are formed on the bottom surface. The lamp-receiving portion is defined in the bottom surface. A backlight module using the present optical plate is also provided.
US07740372B2 Backlight unit and liquid crystal display using the same
A backlight unit includes a plurality a plurality of lamps, each having a first electrode and a second electrode. An alternating current (AC) signal having a high voltage is intermittently applied to the first electrode and the second electrode is connected to a ground. The backlight unit also includes: a pair of lamp guides comprising a first lamp guide and a second lamp guide, wherein the first lamp guide supports the lamps and is disposed to cross the lamps near the first electrodes, and the second lamp guide is disposed to cross the lamps near the second electrodes; a bottom cover for accommodating the lamps and the lamp guide pair; and a plurality of shock-absorbing holes formed in a bottom surface of the bottom cover near the first electrodes, a length of each shock-absorbing hole extending parallel to a corresponding one of the lamps.
US07740371B1 Method and apparatus for pulsed L.E.D. illumination for a camera
An illumination source for a camera includes one or more LEDs, and an electrical circuit that selectively applies power from the DC voltage source to the LEDs, wherein the illumination source is suitable for handheld portable operation. In some embodiments, the electrical circuit further includes a control circuit for driving the LEDs with electrical pulses at a frequency high enough that light produced has an appearance to a human user of being continuous rather than pulsed, the control circuit changing a pulse characteristic to adjust a proportion of light output having the first characteristic color spectrum output to that having the second characteristic color spectrum output. Some embodiments provide an illumination source including a housing including one or more LEDs; and a control circuit that selectively applies power from a source of electric power to the LEDs, thus controlling a light output color spectrum of the LEDs.
US07740368B2 Cap with a light emitting diode (LED) for illuminating a beverage container
A cap for illuminating a beverage container includes a lens, a light emitting diode (LED), a battery, a control circuit, a control button, and a transparent lower section. The LED is mounted between a top cover of the cap and the lens. The LED is positioned to project light downward towards the lens. The control circuit is powered by the battery to drive the LED when activated. The control button is mounted in the top cover of the cap to activate the control circuit. The lower section is mounted to a base of the lens. The lower section is configured to be removably attached to the beverage container.
US07740366B2 Two-sided illumination LED lens and LED module and LED two-sided illumination system using the same
The present invention relates to two-sided illumination LED lens and LED module and an LED two-sided illumination system using the same; and, more particularly, to two-sided illumination LED lens and LED module including an incidence unit on which light impinges; a first exit unit corresponding to the incidence unit and transmitting a portion of the light upward; a reflection unit extended from the first exit unit and reflecting another portion of the light; and a second exit unit facing the first exit unit and transmitting the light reflected at the reflection unit downward, and an LED two-sided illumination system using the same.
US07740363B2 Deformable-mirror holder
This invention relates to a deformable-mirror holder for holding a mirror in a desired position, to within accepted tolerances, even whilst the mirror is deforming or in a deformed state. In particular, this invention relates to a holder for a bimorph mirror. A deformable-mirror holder is provided comprising a body with a central aperture for receiving a deformable mirror, the central aperture being defined by a plurality of flexible beams, with each flexible beam having an end shaped to provide a supporting surface and a flexible portion that connects the beam's end to the holder's body.
US07740362B1 Mirror with thermally controlled radius of curvature
A radius of curvature controlled mirror for controlling precisely the focal point of a laser beam or other light beam. The radius of curvature controlled mirror provides nearly spherical distortion of the mirror in response to differential expansion between the front and rear surfaces of the mirror. The radius of curvature controlled mirror compensates for changes in other optical components due to heating or other physical changes. The radius of curvature controlled mirror includes an arrangement for adjusting the temperature of the front surface and separately adjusting the temperature of the rear surface to control the radius of curvature. The temperature adjustment arrangements can include cooling channels within the mirror body or convection of a gas upon the surface of the mirror. A control system controls the differential expansion between the front and rear surfaces to achieve the desired radius of curvature.
US07740360B2 Image display apparatus
An image display apparatus includes a reflection-type image display device providing partial images that constitute an image frame by reflecting light irradiated from a light-emitting unit, and a distributive projector unit displaying the image frame by discretely projecting the partial images onto different positions.
US07740358B2 Method for determination of a pair of progressive ophthalmic lenses
The invention relates to the determination of a pair of ophthalmic lenses, by measurement of the sagittal plane shift of the wearer for close vision with relation to the standard sagittal plane. Optimisation targets are then chosen as a function of the measured shift. The lenses are determined by optimisation with the chosen targets. Lenses are thus obtained with which the field of close vision is symmetrical with relation to the medial line as perceived by the wearer. A wearer with a displaced sagittal plane thus has a greater close vision field which facilitates binocular vision and increases acuity.
US07740357B2 Deformable mirror device and apparatus for observing retina of eye using the same
A deformable mirror device includes a substrate; a plurality of electrodes provided on the substrate; a spacer disposed on the substrate; a support member disposed above the spacer and having an opening passing through from a first face of the support member facing to the substrate to a second face of the support member opposite from the first face; a deformable electrode film formed below the first face of the support member so as to be opposed to the electrodes with a distance and so as to cover the opening; an insulation film provided between the deformable electrode film and the support member; a reflection film provided on a face of the deformable electrode film opposite from the electrodes so as to overlap the opening; and a plurality of through holes passing through the reflection film and the deformable electrode film and disposed so as to overlap the opening.
US07740350B2 Printing apparatus
An imaging drum maintenance assembly that includes an oil applicator device, and an elastomeric metering blade spaced from the applicator roller and having a bulk resistivity that is less than about 500,000 ohm*meter.
US07740348B2 Liquid ejecting apparatus
A liquid ejecting head is adapted to eject liquid toward a target medium, A transporter is adapted to transport a tray on which the target medium is mounted toward a region facing the liquid ejecting head via a transporting path. A tray guide is disposed in a front side of the liquid ejecting apparatus, and having a supporting face adapted to support the tray thereon. The tray guide is movable between a first position connecting the supporting face with the transporting path to allow the transporter to transport the tray to the transporting path and a second position escaping the supporting face from the transporting path. The supporting face is kept being parallel to the transporting path when the tray guide is moved between the first position and the second position.
US07740343B2 Inkjet printhead integrated circuit with suspended heater element spaced from chamber walls
An inkjet printhead that has a plurality of nozzles and a bubble forming chamber corresponding to each nozzle. The bubble forming chamber of each nozzle has at least one side wall and at least one heater element suspended within each of the bubble forming chambers respectively. Each heater element is configured to heat a bubble forming liquid in the printhead to a temperature above its boiling point to form a gas bubble therein. The generation of the bubble causes the ejection of a drop of an ejectable liquid (such as ink) through an ejection aperture in each nozzle, to effect printing. The heater element is spaced from the side wall of the bubble forming chamber by between 0.1 microns and 20 microns. The nucleation and growth of a gas bubble causes the pressure pulse that ejects ink from the nozzle aperture. By laterally enclosing the bubble with at least one of the side walls of the chamber, most of the pressure is dissipated by ejecting ink through the nozzle.
US07740341B2 Inkjet printhead
An inkjet printhead including a substrate, a plurality of heaters, multiple pairs of leads, an ink chamber layer, and a nozzle plate is provided. The substrate has a top surface and a plurality of ink channels through the substrate in the direction substantially vertical to the top surface. The heaters, the multiple pairs of leads, and the ink chamber layer are disposed on the surface of the substrate. The multiple pairs of leads are electrically coupled to the corresponding heaters respectively, and the heaters are respectively adjacent to the corresponding ink channels. The ink chamber layer has a plurality of ink chambers which respectively expose the corresponding heaters and the corresponding ink channels. The nozzle plate is disposed on the ink chamber layer and has a plurality of nozzles through the nozzle plate.
US07740338B2 Printhead assembly having a pressurised air supply
Provided is a printhead assembly with a pressurised air supply having an elongate ink distribution arrangement that defines a number of inlets, a number of corresponding ink distribution channels and a number of outlets in fluid communication with respective ink distribution channels. The assembly also includes an elongate ink distribution assembly mounted on the ink distribution arrangement, the ink distribution assembly having a plurality of layers together forming a stack, the layers being configured to define a plurality of inlets in fluid communication with the outlets of the ink distribution arrangement and mounting formations with passages opening into the mounting formations, the passages being in the form of ink passage sets in fluid communication with respective ink distribution channels, at least one passage from each set opening into each mounting formation. Also included are printhead integrated circuits mounted in respective mounting formations to receive ink from the passages, and an air duct having a base defining a series of air passages. The assembly further includes an air valve molding formed as a channel with a series of apertures defined in a base thereof, a spacing of the apertures corresponding to the series of air passages, the air valve molding being movable longitudinally within the air duct to facilitate alignment of the apertures with the air passages to allow pressurized air through the laminated stack to the cavity, or moved out of alignment to close off a supply of pressurized air to the cavity.
US07740334B2 Printer system having controller with correction for nozzle displacement
A printing system is provided having a carrier, a printhead module carried by the carrier and a controller. The printhead module has at least one row of ink ejection nozzles. Each of the nozzles is configured to eject ink in response to fire signals from the controller. The controller is configured to determine erroneous rotational displacement of the printhead module relative to the carrier, determine a correction factor based on a thickness of media being printed that at least partially compensates for ink dot displacement by at least one of the nozzles, and using the correction factor, alter the output of the fire signals to the nozzles so as to alter the ejection of ink dots to at least partially compensate for the rotational displacement.
US07740331B2 Refrigerator receptacle
Disclosed is a refrigerator receptacle including a first tray adapted to move into/out of a storage space like a drawer, a reception space being defined in the first tray, the reception space having an upward opening; a second tray adapted to move in an inward/outward movement direction of the first tray, a reception space being defined in the second tray, the reception space having an upward opening; a guide member for guiding movement of the second tray, an insertion groove being formed on the guide member, an upper end of both lateral surfaces of the first tray being inserted into the insertion groove; and a fastener extending through one of the first tray and the guide member so as to be fastened to other of the first tray and the guide member.
US07740330B2 Slide rail
A slide rail includes a first slide, a second slide, and a third slide, each of the first slide, the second slide, and the third slide comprising a pair of sidewalls. The first slide further includes a bottom wall, the pair of the sidewalls are extended from two edges of the bottom wall respectively. The second slide is received in a space bounded by the bottom wall and the sidewalls of the first slide; the sidewalls of the second slide extend out from the space to contact the sidewalls of the third slide.
US07740327B2 Drawer buffer and drawer slide rail with drawer buffer
A drawer Buffer includes: the base, cylinder and plate with the guide rod projected in the front end; the cylinder of which is fixed in the base and there is a projecting column on the front end of its piston rod; in the middle of the guide rod, there is a sliding chute for the move of piston rod; in the outer side of the guide rod, there is a guideway to coordinate with the projecting column, the front end of the guideway is linked with a positioning slot; on the plate, there is the guiding slot for traction and pushing the projecting column into the positioning slot; the section shape of the mentioned cylinder sleeve and piston rod of the cylinder is similar to the ellipse, the tail of the cylinder sleeve is linked with the head of piston rod via the spring. The buffer can be used with a drawer slide rail for drawer moving reposefully.
US07740325B1 Bicycle hub having enhanced strength
A hub for a bicycle includes a shaft, a hub body rotatably mounted on the shaft, a drive seat rotatably mounted on the shaft and engaged with the hub body, and a self-lubricating bearing mounted between the drive seat and the shaft. The self-lubricating bearing has a radially and outwardly extending limit flange rested on the drive seat. Thus, the self-lubricating bearing has an inner wall contacting with an outer wall of the shaft completely and an outer wall contacting with an inner wall of the drive seat completely, so that the external force applied on the self-lubricating bearing is distributed evenly and smoothly to prevent the self-lubricating bearing from being distorted or deformed due to a stress concentration, thereby enhancing the lifetime of the self-lubricating bearing.
US07740324B2 Drainable vehicle wheel and vehicle incorporating same
A drainable vehicle wheel having a hub, a plurality of spokes extending radially from the hub and a rim having tips ends of the spokes connected thereto. Each of the plurality of spokes has a hollow portion and a plurality of water-discharge hole formed therein. The hub has an outer hollow portion formed by a plurality of walls, and one the walls has a drain hole formed therein. The outer hollow portion of the hub is fluidly connected to a hollow portion formed in each of the spokes. A wall of the tip end portion of each of spokes is thickened or reinforced to increase stiffness of the spokes.