| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 161 | METHOD FOR THE PREVENTION AND TREATMENT OF BOVINE MASTITIS | EP94925425.4 | 1994-08-03 | EP0789581B1 | 2001-06-13 | PEEL, John Edmondson; SURI, Bruno |
| A method for treating or preventing mastitis in cows is disclosed. The method contemplates the intramammary injection or dipping the teat with Gallidermin and/or Epidermin or one of their pharmaceutically acceptable acid salts. Gallidermin and/or Epidermin or one of their pharmaceutically acceptable acid salts can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis. | ||||||
| 162 | Qtls for Mastitis Resistance in Cattle | US12223689 | 2007-02-05 | US20100003675A1 | 2010-01-07 | Mogens Sando Lund; Bente Flugel Majgren; Goutam Sahana; Ayman Mahmoud Sabry; Peter Sorensen; Soren Svendsen; Bo Thomsen; Ingrid Lena Anderson-Eklund; Helmi Johanna Vilkki; Christian Bendixen; Terhi Katariina Iso-Touru; Sirja Maria Viitala; Nina Frederika Schulman; Nicola Hastings; John Lewis William Williams; John Arthur Woolliams; Ana Isabel Fernandez Avila; Haldja Viinalass; Sirje Varv |
| The invention relates to a method for determining mastitis resistance in bovine subjects, wherein mastitis resistance comprise resistance to both sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of mastitis resistance in a bovine subject. The determination of mastitis resistance involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with mastitis resistance. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with mastitis resistance, thereby yielding cows less prone to mastitis. | ||||||
| 163 | Method of prophylaxis for bovine mastitis | US09873633 | 2001-06-04 | US06537577B1 | 2003-03-25 | Gregg Andrew Siegel |
| A method is provided for treating bovine mastitis by applying a porous strippable polymer film containing a medicament to the udders of the bovine. | ||||||
| 164 | Method for combatting bovine mastitis | US596203 | 1996-02-16 | US5710124A | 1998-01-20 | John Edmondson Peel; Bruno Suri |
| A method for treating or preventing mastitis in cows is disclosed. The method contemplates the intramammary injection or dipping the teat with Gallidermin and/or Epidermin or one of their pharmaceutically acceptable acid salts. Gallidermin and/or Epidermin or one of their pharmaceutically acceptable acid salts can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis. | ||||||
| 165 | Method of treating bovine masititis | US33566564 | 1964-01-03 | US3347743A | 1967-10-17 | REUTER GERALD L; HILL GEORGE N |
| 166 | Mastitis detector for dairy cattle | US959536 | 1992-10-13 | US5302903A | 1994-04-12 | Hendrik J. De Jong; Albertino B. M. Verstege; Pieter H. Hogewerf |
| A throughflow type mastitis detector having an inlet stub and an outlet stub by means of which the mastitis detector can be coupled to a milk tube; a measuring chamber having side walls, a closed bottom, and an opening opposite said bottom in spaced relationship to said inlet stub, through which opening the milk to be monitored, supplied through the inlet stub, can flow into the measuring chamber, and through which the milk can again leave the measuring chamber when the level of the milk within the measuring chamber exceeds the height of the lowest side wall portion; and a pair of electrodes in the bottom of said measuring chamber for measuring the electrical conductivity of the milk, characterized in that at least one of the electrodes has a convex head projecting above the bottom surface and a shank extending through an opening in the bottom. | ||||||
| 167 | Method of detecting mastitis in cows | US620157 | 1984-06-13 | US4659656A | 1987-04-21 | Markus Sandholm |
| There is disclosed a method for the quantitative determination of mastitis in a cow. This method comprises decaseinating and delipidating a milk sample from the cow to obtain a clear solution, substantially removing .alpha..sub.2 -macroglobulin from the sample, mixing the clear and substantially .alpha..sub.2 -macroglobulin free sample with a known amount to trypsin, and measuring the activity of the amount of trypsin which is in excess of the amount which is inactivated by the milk's antitrypsin. | ||||||
| 168 | Method of treating bovine mastitis | US58368656 | 1956-05-09 | US2908609A | 1959-10-13 | ATERNO JOSEPH P; LUTHER HERBERT G; HAWLEY GAIL E; SACCHI EDWARD M |
| 169 | Method for identifying cows with mastitis by bulk genotyping of tank milk | EP11190186.4 | 2011-11-28 | EP2597159A1 | 2013-05-29 | Georges, Michel; Blard, Grégoire; Coppieters, Wouter |
A method for indirectly quantifying the number of somatic cells in the milk of an individual animal, the method comprising the steps of: |
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| 170 | Bovine serum and bovine IgG as preventives and therapeutives for bovine mastitis | US177833 | 1994-01-05 | US5700465A | 1997-12-23 | Weng Tao; Martin John Corbett; Walter C. Pickett |
| Immunoglobulin G-2 (IgG2), e g. bovine IgG2, and its reaction with neutrophils can be used to enhance the neutrophil's functional status in host animal defense against bacterial infections. | ||||||
| 171 | Method for identifying cows with mastitis by bulk genotyping of tank milk | EP11190186.4 | 2011-11-28 | EP2597159B1 | 2014-01-29 | Georges, Michel; Blard, Grégoire; Coppieters, Wouter |
| A method for indirectly quantifying the number of somatic cells in the milk of an individual animal, the method comprising the steps of: a.obtaining a sample of milk from the farm's milk tank, b.extracting DNA from said sample, c.genotyping said DNA for a collection of DNA sequence polymorphisms, d.quantifying the proportion of the different alleles for each of the said DNA sequence polymorphisms in said DNA, e.estimating the proportion of DNA contributed by each animal on the farm to tank's milk, f.estimating the somatic cell scores of each animal on the farm from said proportion of DNA contributed. | ||||||
| 172 | Compounds for Treatment of Bovine Mastitis | US13703406 | 2011-06-13 | US20130281442A1 | 2013-10-24 | Barry Hafkin |
| Described herein are methods of treating mastitis in female mammals, e.g., cows, wherein the methods may include administering to mammals in need thereof compounds disclosed herein. | ||||||
| 173 | Method for determining quality of milk and presence of mastitis | US11137826 | 2005-05-25 | US20060280848A1 | 2006-12-14 | Geofrey Westfall |
| Methods of determining the quality of milk due to the presence of mastitis, by monitoring the concentration of various ions, and ratios of those ions, in the milk. As the level of mastitic infection progresses, the concentrations of sodium and chloride ions increase and the concentrations of potassium and calcium ions decrease. A ratio of sodium to potassium is more sensitive to infection detection than either ion concentration alone. Similarly, sodium to calcium, chloride to potassium and chloride to calcium is more sensitive than any of the ions alone. | ||||||
| 174 | Method for the prevention and treatment of bovine mastitis | US751181 | 1991-08-28 | US5234684A | 1993-08-10 | Lorraine M. Sordillo; Lorne A. Babiuk |
| A method for treating or preventing mastitis in cows is disclosed. The method contemplates the intramammary injection of bovine interferon-gamma. Interferon-gamma can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis. | ||||||
| 175 | Diagnostic test for Staphylococcal mastitis in cattle | US936750 | 1986-12-02 | US4849341A | 1989-07-18 | D. Scott Adams; Irwin C. McGuire, Jr. |
| The present invention relates to (1) an enzyme-linked immunosorbent assay (ELISA) for detection in milk of antibodies of any isotype which are specific for Staphylococcus aureus proteins in molecular weights ranging from 18,000 to 26,000 daltons, (2) a process for production and purification of said proteins, (3) a method of performing said ELISA utilizing said proteins and (4) use of said ELISA for detection of intramammary infection by S. aureus. | ||||||
| 176 | Bovine mastitis vaccine and method for detecting efficacy thereof | US265287 | 1981-05-20 | US4425330A | 1984-01-10 | Neil L. Norcross; Johanna P. Opdebeeck |
| This invention relates to a vaccine for the prevention and/or control of gram-positive cocci, e.g. Str. agalactiae and S. aureus, induced bovine mastitis infections and to an immunological method, an enzyme linked immunosorbent assay (ELISA), for assaying the humoral immue response of the lactating bovine mammary gland to detect antibody variables associated with the vaccinated or suspected infected bovine. | ||||||
| 177 | Implant for inhibiting mastitis in dairy cattle | US285259 | 1981-07-20 | US4418686A | 1983-12-06 | Francis W. Child |
| A method and instrument for placing an implant in the teat duct and udder of an animal, as a milk cow. The instrument has an elongated tubular member having a passage accommodating the implant. The tubular member is adapted to be inserted into the milk duct through the discharge end thereof. A head having finger gripping ears is attached to the tubular member. The implant is moved from the passage with a piston connected to a rod extended through the head. A hand engaging member secured to the rod is used in cooperation with the ears to apply force to the rod to move the piston in the passage to move the implant into the teat duct and udder. The implant has a core of an elongated flexible plastic string. A plurality of bands are clamped about the core. Alternate bands are coated with a first metal, as silver. The remaining bands are coated with a second metal, as gold. All of the bands may be coated with the same metal, such as silver. The implant includes a capsule implant containing material that reacts with the silver to produce silver ions which have advantageous antibacterial effects. | ||||||
| 178 | Product and process for treating bovine mastitis and bovine metritis | US913034 | 1992-07-14 | US5260341A | 1993-11-09 | A. H. J. Rajamannan |
| A product for treating bovine mastitis and bovine metritis includes mixture of diacetyl and acetoin. The diacetyl and acetoin is produced by fermentation of milk and is then distilled and concentrated. The concentrated mixture of diacetyl and acetoin is infused into the udder cistern of a cow when treating mastitis, and is infused into the uterus of a cow when treating metritis. | ||||||
| 179 | Method for determining quality of milk and presence of mastitis | US11137826 | 2005-05-25 | US08076143B2 | 2011-12-13 | Geofrey J. Westfall |
| Methods of determining the quality of milk due to the presence of mastitis, by monitoring the concentration of various ions, and ratios of those ions, in the milk. As the level of mastitic infection progresses, the concentrations of sodium and chloride ions increase and the concentrations of potassium and calcium ions decrease. A ratio of sodium to potassium is more sensitive to infection detection than either ion concentration alone. Similarly, sodium to calcium, chloride to potassium and chloride to calcium is more sensitive than any of the ions alone. | ||||||
| 180 | Antimicrobial composition useful for the treatment of bovine mastitis | US09619788 | 2000-07-20 | US06582734B1 | 2003-06-24 | Guang-jong Jason Wei; David Daniel McSherry; Francis Lawrence Richter; Richard K. Staub |
| The present invention relates to a two-part antimicrobial composition comprising at least one chlorine dioxide generating component comprising at least one metal chlorite and at least one acid-forming compound in a solid carrier, and at least one liquid aqueous component. The composition further comprises at least one antimicrobial fatty acid having from about 2 to about 15 carbon atoms, and preferably from about 6 to about 12 carbon atoms. The components, upon mixing, form a composition having a pH in the range of about 5 to about 10. | ||||||
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