| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 141 | 影响奶牛乳腺炎易感/抗性HMGB3基因的核心启动子及其功能性分子标记与应用 | CN201210257692.9 | 2012-07-25 | CN102899396A | 2013-01-30 | 黄金明; 王秀革; 李黎明; 鞠志花; 齐超; 张燕; 李秋玲; 王长法; 李荣岭; 杭苏琴; 侯明海; 高运东; 仲跻峰 |
| 本发明提供一种影响奶牛乳腺炎易感/抗性HMGB3基因的核心启动子及其功能性分子标记与应用，属于生物化学遗传育种技术领域，具体是通过反转录RT-PCR和实时荧光定量RT-qPCR的方法提供一个奶牛乳腺炎易感/抗性HMGB3候选基因，利用牛HMGB3基因P3启动子区的1个功能性SNP位点的信息，并且采用分子生物学相关技术鉴别奶牛在这个位点的基因型，选择具有乳腺炎抗性的基因型个体。选择有利的基因型个体留种，可以提高HMGB3基因抗性基因型在奶牛群体中的频率，从而提高群体抗奶牛乳腺炎的能力，降低奶牛乳腺炎的发病率，减少经济损失。本发明为奶牛的乳腺炎抗性遗传改良提供了一种新的方法。 | ||||||
| 142 | 一类具有二氨基吡咯并喹唑啉结构的化合物在防治奶牛乳腺炎致病菌中的用途 | CN202311685814.9 | 2023-12-11 | CN117815240A | 2024-04-05 | 刘映前; 周翰; 金亚瑞 |
| 本发明公开系列一类具有二氨基吡咯并喹唑啉结构的化合物在防治奶牛乳腺炎致病菌中的用途，属于天然药物化学领域。该类衍生物对奶牛乳腺炎致病菌无乳链球菌Streptococcus agalactiae ATCC12386，无乳链球菌Streptococcus agalactiae ATCC27956，停乳链球菌Streptococcus dysgalactiae ATCC27957表现出优异的抑制活性。本发明所涉及化合物合成路线简单且原料廉价易得，具有进一步开发的价值。所涉及化合物结构式如下： | ||||||
| 143 | 一种用于检测奶牛乳腺炎性金黄色葡萄球菌青霉素耐药基因的分子标记及其应用 | CN201710456952.8 | 2017-06-16 | CN107164503A | 2017-09-15 | 吕少波; 李苏杨; 李卓才 |
| 本发明公开了一种用于检测奶牛乳腺炎性金黄色葡萄球菌青霉素耐药基因的分子标记及其应用，所述分子标记及其序列为：P1，SEQ ID NO.1～2；P2，SEQ ID NO.3～4；P3，SEQ ID NO.5～6。(1)本发明所述分子标记具有重复性好、可比性强和分辨力高等优点；(2)所述方法无需大量测序，应用成本低。 | ||||||
| 144 | 젓소의 유방염 검출회로 | KR2019860007925 | 1986-06-04 | KR2019890002682Y1 | 1989-04-29 | 송기춘; 오일환 |
| 내용 없음. | ||||||
| 145 | 一种用于检测奶牛乳腺炎病原微生物耐药性的芯片 | CN201520560720.3 | 2015-07-29 | CN205011760U | 2016-02-03 | 车团结; 胡巍; 徐进章; 张成虎; 魏锁成 |
| 本实用新型提供一种用于检测奶牛乳腺炎病原微生物耐药性的芯片，所述芯片包括芯片主体，所述芯片主体上有12个凹槽，分别为：庆大霉素MH培养基凹槽，左氧氟沙星MH培养基凹槽，环丙沙星MH培养基凹槽，青霉素MH培养基凹槽，头孢曲松拉MH培养基凹槽，四环素MH培养基凹槽，红霉素MH培养基凹槽，卡那霉素MH培养基凹槽，克林霉素MH培养基凹槽，氟哌酸MH培养基凹槽，先锋VMH培养基凹槽，去离子水MH培养基凹槽。本实用新型的芯片能够高通量检测奶牛乳腺炎病原微生物及牛奶残留病原微生物的耐药性，大大降低了检测人员的劳动强度，减少了培养基的消耗，降低了成本，使用也更加方便；检测结果能够用肉眼判断。 | ||||||
| 146 | 一种用于检测奶牛乳腺炎病原微生物及牛奶残留病原微生物的芯片 | CN201520557060.3 | 2015-07-29 | CN204939479U | 2016-01-06 | 车团结; 胡巍; 徐进章; 张成虎; 魏锁成 |
| 本实用新型提供一种用于检测奶牛乳腺炎病原微生物及牛奶残留病原微生物的芯片，所述芯片包括芯片主体，所述芯片主体上有12个凹槽，分别为：Baird-Parker培养基凹槽，伊红美蓝培养基凹槽，BETA-SSA培养基凹槽，无乳链球菌显色培养基凹槽，B族链球菌培养基凹槽，克雷伯氏菌显色培养基凹槽，KF链球菌培养基凹槽，PALCAM培养基凹槽，沙门志贺菌属琼脂培养基凹槽，十六烷三甲基溴化铵琼脂培养基凹槽，沙保弱琼脂培养基凹槽，营养琼脂培养基凹槽。本实用新型的芯片能够同时检测引起奶牛乳腺炎的各种病原微生物以及牛奶残留的各种病原微生物，大大降低了检测人员的劳动强度，减少了培养基的消耗，降低了成本。 | ||||||
| 147 | 젖소 유방염 치료용 조성물 | KR1020100011967 | 2010-02-09 | KR101156082B1 | 2012-06-20 | 심승규; 김동건; 황용배; 김영희 |
| 본 발명은 정제봉독, 키토산 및 프로폴리스를 포함하는 젖소 유방염 치료용 조성물에 관한 것으로서, 상기 조성물은 상용봉독, 키토산 또는 프로폴리스 단독에 비해 상승된 효과를 나타내므로, 젖소 유방염 치료에 유용하게 사용될 수 있다.
|
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| 148 | QTLS FOR MASTITIS RESISTANCE IN CATTLE | EP07702476.8 | 2007-02-05 | EP2069531A2 | 2009-06-17 | LUND, Mogens, Sandø; BENDIXEN, Christian; SAHANA, Goutam; SØRENSEN, Peter; SVENDSEN, Søren; THOMSEN, Bo; MAJGREN, Bente, Flügel; SABRY, Ayman, Mahmoud; ANDERSSON-EKLUND, Ingrid, Lena; VILKKI, Helmi, Johanna; ISO-TOURU, Terhi, Katarlina; VIITALA, Sirja, Maria; SCHULMAN, Nina, Frederika; HASTINGS, Nicola; WILLIAMS, John, Lewis, William; WOOLLIAMS, John, Arthur; ÀVILA, Ana Isabel Fernández; VIINALASS, Haldja; VÅRV. Sirje |
| The invention relates to a method for determining mastitis resistance in bovine subjects, wherein mastitis resistance comprise resistance to both sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of mastitis resistance in a bovine subject. The determination of mastitis resistance involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with mastitis resistance. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with mastitis resistance, thereby yielding cows less prone to mastitis. | ||||||
| 149 | QTLS FOR MASTITIS RESISTANCE IN CATTLE | EP07702476.8 | 2007-02-05 | EP2069531B1 | 2013-04-10 | LUND, Mogens, Sandø; BENDIXEN, Christian; SAHANA, Goutam; SØRENSEN, Peter; SVENDSEN, Søren; THOMSEN, Bo; MAJGREN, Bente, Flügel; SABRY, Ayman, Mahmoud; ANDERSSON-EKLUND, Ingrid, Lena; VILKKI, Helmi, Johanna; ISO-TOURU, Terhi, Katarlina; VIITALA, Sirja, Maria; SCHULMAN, Nina, Frederika; HASTINGS, Nicola; WILLIAMS, John, Lewis, William; WOOLLIAMS, John, Arthur; ÀVILA, Ana Isabel Fernández; VIINALASS, Haldja; VÅRV, Sirje |
| 150 | 家畜用乳頭パック材料及び乳用家畜の乳房炎予防方法 | JP2016041401 | 2016-03-03 | JP2016214233A | 2016-12-22 | 近藤 仁志; 乾 洋治; 風間 秀樹 |
| 【課題】家畜の、主として乳牛の乳頭を乳房炎から予防するために使用される乳頭パック材料において、容易な操作により形成させることができるものであり、かつパック同士の癒着を防ぐことが可能である家畜用乳頭パック材料を提供する。 【解決手段】(A)高分子ラテックス、及び(B)離型剤を含む家畜の乳頭に密着させるためのパックを形成するための家畜用乳頭パック材料であり、該材料により幅20mm、長さ100mm、厚さ0.1mmのPETフィルム上に形成された2枚の厚さ0.1mmの膜を1Nで接触させ、続いてそれらの2枚の膜を180°方向に引きはがす際に要する力である粘着力が0.3N/10mm以下である家畜用乳頭パック材料。 【選択図】なし |
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| 151 | 젖소의 유두 소독과 유방염 예방을 위한 유두침지액 | KR1019980015847 | 1998-05-02 | KR100299669B1 | 2001-10-27 | 민경우; 김덕원 |
| PURPOSE: A solution containing chitosan, sodium benzoate and didecyldimethylammonium chloride to soak a nipple therein is provided which is free from irritation to the skin, protects the skin by formation of a film on the nipple and prevents invasion of bacteria that cause mastitis. CONSTITUTION: This solution comprises 0.4% by weight of chitosan, 0.1% by weight of sodium benzoate, 0.006% by weight of didecyldimethylammonium chloride and the remaining of distilled water and has a pH of 4.5 to 5.5. The solution also contains an acid or alkali and a pharmaceutically additive. | ||||||
| 152 | 家畜用乳頭パック材料及び乳用家畜の乳房炎予防方法 | JP2016054600 | 2016-03-18 | JP2016214234A | 2016-12-22 | 近藤 仁志; 乾 洋治; 風間 秀樹 |
| 【課題】 家畜の、主として乳牛の乳頭を乳房炎から予防するために使用される乳頭パックにおいて、乳頭が脂ぎっている場合においても均一な厚みのパックを容易な操作により形成させることができ、長期間乳頭に密着する家畜用乳頭パック材料を提供する。 【解決手段】 家畜の乳頭に密着させるパックを形成するための材料であって、(A)ラテックスと(B)界面活性剤を含み、かつ(B)界面活性剤の含有量が0.05質量%以上10質量%以下であることを特徴とする家畜用乳頭パック材料である。 【選択図】なし |
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| 153 | Treatment of mastitis in bovine udders | US438365 | 1974-01-31 | US3950554A | 1976-04-13 | Emanuel C. Prince |
| Mastitis in bovine udders is treated and controlled by dipping the teats into a composition consisting essentially of a semi-drying oil and a fatty acid ester and allowing the teat to dry to form a water repellent film on the teat skin and across the teat orifice. The composition may also contain a bactericide, a healing agent, a hydration agent and a dye. | ||||||
| 154 | Control of bovine mastitis | US615282 | 1975-09-22 | US4025628A | 1977-05-24 | Lloyd G. Dewey; James J. Jezeski |
| A powdered, storage stable, effervescent formulation readily dispersible in water and containing a watersoluble chlorinated cyanurate, such as sodium dichloroisocyanurate, is mixed with water to provide a stable, slightly acid to neutral, non-irritating aqueous liquid having about 3,000 to 7,000 ppm titratable chlorine which is used as a teat dip for hygienic control of bovine mastitis. | ||||||
| 155 | Bovine mastitis treatment | US547617 | 1995-10-24 | US5846543A | 1998-12-08 | Mark A. Hassler; Lisa M. Hassler |
| Chemical compositions for the treatment of bovine mastitis which compositions are combinations of four components i.e.; Echinechea Goldenseal Supreme; Wild Ginseng Supreme; gelsemium, pokeroot, and aconite; and aloe vera juice, which form a dose which is injected into the mastitis affected portion of a cow's udder for a minimum of two doses per day for at least three days, which results in a cure for the mastitis. | ||||||
| 156 | 키토산 또는 키토산 올리고당을유효성분으로 하는 젖소의 유방염 치료제 | KR1019980033405 | 1998-08-18 | KR100321932B1 | 2002-09-05 | 김희경; 강문일; 김희선; 김광윤; 김종염; 주이석; 문진산 |
| PURPOSE: Provided is a prophylactic and therapeutic agent containing chitosan and chitosan-oligosaccharide as an active ingredient for mastitis in a milch cow. CONSTITUTION: A prophylactic and therapeutic agent containing chitosan and chitosan-oligosaccharide as an active ingredient is characterized by adding 0.5-0.0001 wt.% of chitosan-oligosaccharide having 1-16 glycones(66.3-97.5%), acetylation rate of 75-100%, and molecular weight of 104-2310 to a livestock feed. It is dissolved in water and orally administered into a milch cow. | ||||||
| 157 | 소의 유방염 진단기구 및 이를 이용한 진단방법 | KR1019990040420 | 1999-09-20 | KR100315667B1 | 2001-11-30 | 김용철; 정충일; 이재현; 박홍양 |
| 본발명은소의유방염을일으키는균주의다가항체(polyclonal antibodies) 및단가항체(monoclonal antibodies)를제조한후 소에서채취한우유내유방염항원과항원·항체반응을일으켜소의유방염을정확하게진단하는진단기구및 이를이용한진단방법에관한것으로소의유방염원인균주의다가항체및 단가항체를라텍스, 염색졸 및금 졸로염색하여테스트멤브레인에적용시키므로유방염에감염된소의우유와반응시킬경우테스트멤브레인내의색깔을관찰하여유방염감염여부를신속, 정확하게진단할수 있는뛰어난효과가있다. | ||||||
| 158 | METHOD FOR THE PREVENTION AND TREATMENT OF BOVINE MASTITIS | EP94925425.0 | 1994-08-03 | EP0789581A1 | 1997-08-20 | PEEL, John Edmondson; SURI, Bruno |
| A method for treating or preventing mastitis in cows is disclosed. The method contemplates the intramammary injection or dipping the teat with Gallidermin and/or Epidermin or one of their pharmaceutically acceptable acid salts. Gallidermin and/or Epidermin or one of their pharmaceutically acceptable acid salts can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis. | ||||||
| 159 | Early diagnosis of mastitis or garget in milk | EP91306798.9 | 1991-07-25 | EP0472295B1 | 1995-09-27 | Yamamoto, Hideo, Sanwa Kagaku Kenkyusho Co., Ltd.; Furukawa, Eiji, Sanwa Kagaku Kenkyusho Co., Ltd.; Asai, Hiromoto, Sanwa Kagaku Kenkyusho Co., Ltd.; Kurono, Masayasu c/o Sanwa Kagaku Kenkyusho Co.Ltd; Sawai, Kiichi c/o Sanwa Kagaku Kenkyusho C0.Ltd |
| 160 | COMPOUNDS FOR TREATMENT OF BOVINE MASTITIS | EP11793310.1 | 2011-06-13 | EP2579863A2 | 2013-04-17 | HAFKIN, Barry |
| Described herein are methods of treating mastitis in female mammals, e.g., cows, wherein the methods may include administering to mammals in need thereof compounds disclosed herein. | ||||||
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