序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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261 | 콜레라 독소 B 서브유닛과 바이러스 항원 단백질의 융합 항원 단백질 백신, 이를 발현하는 식물체 및 이의 용도 | KR1020130002649 | 2013-01-09 | KR101566002B1 | 2015-11-05 | 양문식 |
본발명은콜레라독소 B 서브유닛과댕기바이러스항원단백질의융합항원단백질을이용한댕기바이러스백신에관한것으로, 콜레라독소 B 서브유닛 (cholera toxin B subunit; CTB)과댕기바이러스외피당단백질도메인 III (synthetic consensus dengue virus envelope protein domain III) 단백질이융합된 CTB-scEDIII 단백질을생산하는형질전환식물체는경구백신으로사용될수 있으며, 4가지혈청형의댕기바이러스에대한교차-중화활성을갖는항체형성을유도하여 4가지혈청형의댕기바이러스에대한감염을예방할수 있다. | ||||||
262 | 장관내독소 B 서브유닛과 ApxIIA 융합단편을 포함하는 재조합 유전자, 이를 발현하는 식물체 및 이의 용도 | KR1020100121786 | 2010-12-02 | KR101211396B1 | 2012-12-11 | 양문식; 김태금 |
본발명은대장균유래장관내독소 B 서브유닛(LTB) 유전자및 악티노바실러스플루로뉴모니애유래 ApxIIA유전자단편으로구성된융합유전자를포함하는재조합식물발현벡터, 상기벡터로형질전환된식물체및 이의종자, 상기벡터로식물체를형질전환시켜, 융합유전자를발현하는단계를포함하는 LTB-ApxIIA융합단백질의제조방법, 상기방법으로제조된재조합 LTB-ApxIIA 융합단백질을활성성분으로포함하는것을특징으로하는돼지흉막폐렴백신조성물에관한것이다. | ||||||
263 | COMPOSITIONS, METHOD AND USE OF COMPOUNDS MADE UP OF MICROORGANISMS FOR CONTROLLING PHYTOPATOGENIC AND/OR MYCOTOXIGENIC FUNGI AND LIMITING MYCOTOXIN LEVELS | PCT/IT2008/000182 | 2008-03-19 | WO2008114304A2 | 2008-09-25 | CASTORIA Raffaollo,; DE CICCO Vincenzo; DE CURTIS Filippo; LIMA Giuseppe |
The invention consists of a method for controlling fungal phytopathogens by applying compositions to grape vines and cereals in the field. These compositions are based on antagonistic microorganisms which are not only able to protect plants from phytopathogenic microorganisms, including mycotoxigenic agents, but they are also able to reduce the quantity of mycotoxins present in the edible portions since antagonist microorganisms also control mycotoxigenic fungi, even those already present at the time of application. The preparation of these compositions and their practical agricultural use are also described. |
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264 | 감태 추출물 또는 이로부터 분리한 플로로탄닌계 화합물을 유효성분으로 포함하는 인플루엔자의 예방 또는 치료용 조성물 | PCT/KR2017/012550 | 2017-11-07 | WO2018088777A1 | 2018-05-17 | 조태오; 오원근; 이준식; 조광원; 하티킴쿠이; 초효문 |
본 발명은 감태(Ecklonia cava) 추출물 또는 이로부터 분리한 플로로탄닌계 화합물을 유효성분으로 포함하는 인플루엔자의 예방 또는 치료용 조성물에 관한 것이다. 감태 추출물 또는 이로부터 분리한 플로로탄닌계 화합물인 디벤조[1,4]디오신-2,4,7,9-테트라올(Dibenzo[1,4]dioxine-2,4,7,9-tetraol)(화합물 1), 디옥시노데히드로에콜(Dioxinodehydroeckol)(화합물 2) 및 6,6'-비에콜(6,6'-bieckol)(화합물 3)이 조류 인플루엔자 바이러스 또는 돼지 인플루엔자 바이러스에 대해 항바이러스 활성을 가지고 있어, 인플루엔자 예방 및 치료용 조성물 개발에 유용하게 이용할 수 있을 것으로 기대된다. |
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265 | 含菲杂环类化合物及其制备方法和抗植物病毒应用 | PCT/CN2014/082337 | 2014-07-16 | WO2015027772A1 | 2015-03-05 | 汪清民; 刘玉秀; 王兹稳; 魏朋; 王蕾; 马双 |
公开了通式(I)所示的含菲杂环类化合物及其制备和在农药上的应用。该化合物的合成方法简单,易于工业化生产。所述含菲杂环类化合物可用作抗植物病毒剂来抑制烟草花叶病毒、辣椒病毒、水稻病毒、番茄病毒、甘薯病毒、马铃薯病毒和瓜类病毒及玉米矮花叶病毒等,尤其是抑制烟草花叶病毒。通式(I)中R1、R2、R3、X1-X7、m和n定义如说明书。 |
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266 | NOUVELLE UTILISATION DE SPORES , DE PROTEINES OU D ' ENDOTOXINES DE BACILLUS SPHAERICUS ET DE BACILLUS THURINGIENSIS COMME STIMULATEURS DES DEFENSES NATURELLES DES PLANTES | PCT/FR2005/003177 | 2005-12-16 | WO2006067318A1 | 2006-06-29 | BESNARD, Olivier |
L'invention concerne une nouvelle utilisation de spores, de protéines ou de delta- endotoxines issues : - de clones de Bacillus thu®ngiensis var kurstaki de Barjac et Lemille (sérotype 3a et 3b) déposé à l'ATCC sous le N0 33679 ; - de clones de Bacillus thuringiensis var israelensis de Barjac (sérotype H 14) déposé à l'ATCC sous le N0 35646 ; - de clones de Bacillus sphaericus déposé à l'ATCC sous le N° 10208 ; comme stimulateur des défenses naturelles des plantes entières par application foliaire, racinaire ou par injection, contre les pathogènes des cultures des types fongiques et/ou bactériens et/ou viraux. |
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267 | PHARMACEUTICAL PROTEINS, HUMAN THERAPEUTICS, HUMAN SERUM ALBUMIN, INSULIN, NATIVE CHOLERA TOXIC B SUBMITTED ON TRANSGENICS PLASTIDS | PCT/US0106288 | 2001-02-28 | WO0172959A2 | 2001-10-04 | DANIELL HENRY |
Plastid transformation vectors are described that encode a variety of biopharmaceutical proteins, including proinsulin and proinsulin fusion proteins, interferon, growth factors, cholera toxin, and human serum albumin. Vectors are also described that encode GVGVP polymers, Cry2aA2, and chaperonins. | ||||||
268 | METHOD OF PRODUCING CLOSTRIDIUM BOTULINUM TOXIN USING MEDIA CONTAINING PLANT-DERIVED COMPONENTS AND FLEXIBLE CLOSED CONTAINER | PCT/KR2008/003897 | 2008-07-02 | WO2009142352A1 | 2009-11-26 | JUNG, Hyun-Ho; YANG, Gi-Hyeok; KIM, Hack-Woo; LEE, Byung-Kook; YOON, Young-Suk; HONG, Hyung-Pyo |
Provided are a method of producing Clostridium botulinum toxin by using a media containing plant-derived components, and a method of producing Clostridium botulinum toxin by using a flexible closed container. |
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269 | TREATMENT OF PLANTS, FRUITS AND VEGETABLES TO INCREASE GROWTH, ELIMINATE INSECTS AND INCREASE SHELF-LIFE WITH ALOE VERA GEL | PCT/US2007/084998 | 2007-11-16 | WO2008061235A2 | 2008-05-22 | COATS, Billy, C. |
The present invention includes compositions and methods for the treatment of plants against pathogens, elimination of insects and to increase the shelf-life of fruits and vegetables that includes coating the plant with undiluted aloe vera gel. |
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270 | INSECT-RESISTANT TRANSGENIC PLANTS AND METHODS FOR IMPROVING delta -ENDOTOXIN ACTIVITY AGAINST TARGET INSECTS | PCT/US9826852 | 1998-12-17 | WO9931248A9 | 1999-09-16 | ENGLISH LEIGH; BRUSSOCK SUSAN M; MALVAR THOMAS M; BRYSON JAMES W; KULESZA CAROLINE A; WALTERS FREDERICK S; SLATIN STEPHEN L; VON TERSCH MICHAEL A; ROMANO CHARLES |
Disclosed are methods for increasing the activity of B. thuringiensis delta -endotoxins against Coleopteran insect pests. Also disclosed are methods for mutagenizing nucleic acid sequences encoding these polypeptides, and increasing insect resistance in transgenic plants expressing these genes. | ||||||
271 | MYCOTOXIN BINDING FOOD AND FEED ADDITIVES AND PROCESSING AIDS, FUNGISTATIC AND BACTERIOSTATIC PLANT PROTECTING AGENTS AND METHODS OF UTILIZING THE SAME | PCT/US2011/051666 | 2011-09-15 | WO2012037297A1 | 2012-03-22 | TRANQUIL, Dennis, Theodore; KANARSKY, Albert, Vladimiirovich; TRANQUIL, Elizabeth; KANARSKAYA, Zosya, Albertovna; KOPYLOV, Arthur, Tigranovich |
Method is proposed useful to render harmless mycotoxins that contaminate food, animal feed and assist infection of plant hosts by microbial parasites, comprising binding mycotoxins by a novel adsorbent, consisting partially or in full of plant lignocellulosic biomass or isolated biomass components, e.g., acid hydrolysis lignin, enzymatic hydrolysis lignin, coniferous and deciduous wood, bark and needle particles, rice hulls, used coffee grounds, apricot stone shells, almond, walnut, sunflower hulls, cocoa and peanut shells. The materials may be further improved through genetic modification of plants and physicochemical treatment of lignocellulosic biomass, such as micronization. The resulting adsorbent can bind wide range of mycotoxins, including mycotoxins difficult to bind (Ochratoxin, T-2, Deoxynivalenol, Nivalenol). Ability of porous materials containing lignin to thermally collapse at melting can be used to irreversibly entrap mycotoxins by adsorbing them in a wet system and then closing lignin pore structure under high-temperature treatment, such as drying. |
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272 | Suppression of Gliocladium virens phytotoxin production with steroid inhibitors | US901439 | 1992-06-19 | US5268173A | 1993-12-07 | Charles R. Howell; Robert D. Stipanovic |
A process for producing cultures of Gliocladium virens for use as biocontrol agents wherein the production of viridiol is inhibited. Cells of Gliocladium virens are grown in a culture medium and under conditions effective to produce gliotoxin and/or gliovirin, wherein the culture medium includes an amount of a fungicidal steroid inhibitor which is effective to inhibit production of viridiol but which does not substantially inhibit the growth of G. virens. Following recovery, the resultant culture may be used as a biocontrol agent for the control of plant diseases by application to the locus of a plant, seedling or seed to be protected. Coating seeds with the biocontrol agent prior to planting has been found to be particularly effective for the control of soilborne root or seedling diseases. | ||||||
273 | Insektizide Toxine, Gene, die diese Toxine kodieren, Antikörper, die sie binden, sowie transgene Pflanzenzellen und transgene Pflanzen, die diese Toxine exprimieren | EP89123226.6 | 1989-12-15 | EP0374753A3 | 1991-05-29 | Zlotkin, Eliahu; Eitan, Michal; Ben-Yehuda, Oz; Fowler, Elizabeth; Belagaje, Rama M.; Roberts, Jean L. |
Diese Erfindung betrifft transgene Pflanzen, Pflanzenzellen und Mikroorganismen, die unter Einsatz der rekombinanten DNA-Techniken so transformiert sind, dass sie selektiv auf Insekten wirkende Toxine aus giftigen Tieren, vorteilhafterweise aus Vertretern des Stammes Arthropoda, insbesondere aus Vertretern der Klasse Arachnida (Spinnentiere), vor allem aus Vertretern der Ordnung Scorpiones, sowie insbesondere aus Vertretern der Klasse Chilopoda (Hundertfüssler) synthetisieren können. Die Erfindung betrifft ferner Gene, die besagte Toxine kodieren, und den Einsatz dieser Gene, um Pflanzen eine genetisch vermittelte Resistenz gegenüber Insekten zu verleihen und um phytopathogene Insekten zu bekämpfen. Die Erfindung betrifft auch ein Toxin aus dem Gift des Skorpions Leiurus quinquestriatus hebraeus mit der Aminosäuresequenz VRDAYIAKNY NCVYECFRDA YCNELCTKNG ASSGYCQWAG KYGNACWCYA LPDNVPIRVP GKCR. Die Erfindung betrifft weiterhin Antikörper gegen besagte Toxine und insektizide Mittel, die besagte Toxine enthalten. |
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274 | CONOTOXIN PEPTIDES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EP14803477.0 | 2014-05-30 | EP3003344A1 | 2016-04-13 | MCINTOSH, J. Michael |
The present disclosure describes analog conotoxin peptides of the α-contoxin peptide RgIA. These analog conotoxin peptides block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain, inflammatory conditions, inflammation, and/or cancer. | ||||||
275 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL FOR THE REDUCTION OF MYCOTOXIN CONTAMINATION IN PLANTS | EP11788178.9 | 2011-11-28 | EP2645859A1 | 2013-10-09 | HOFFMANN, Sebastian; MEISSNER, Ruth; COQUERON, Pierre-Yves; DESBORDES, Philippe |
The present invention relates to the novel use of pyrazole carboxylic acid amides, compositions comprising these compounds and their use in methods for the reduction of mycotoxin contamination in plants. | ||||||
276 | PLANT-OPTIMIZED GENES ENCODING PESTICIDAL TOXINS | EP98956551.0 | 1998-11-04 | EP1029056B1 | 2006-01-11 | CARDINEAU, Guy, A.; STELMAN, Steven, J.; NARVA, Kenneth, E. |
The subject invention concerns materials and methods useful in the control of pests and, particularly, plant pests. More specifically, the subject invention provides plant-optimized, polynucleotide sequences that encode pesticidal toxins (full-lengthand truncated). Truncated polynucleotide sequences can be used to produce truncated toxins or for the production of fusion (or chimeric) genes and proteins. The polynucleotide sequences of the subject invention have certain modifications, compared to wild-type sequences, that make them particularly well-suited for optimized expression in plants. Using techniques known to those skilled in the art, the polynucleotide sequences described herein can be used to transform plants in order to confer pest resistance upon the plants. | ||||||
277 | EXPRESSION IN PLANTS OF ANTIBODIES AGAINST ENTEROTOXIGENIC ESCHERICHIA COLI | EP04711367.5 | 2004-02-16 | EP1597372A2 | 2005-11-23 | BROWN, Devon,Syngenta Limited; CAMPOS, Manuel,Syngenta Limited; DALMIA, Bipin,Syngenta Limited; DEMAREST, Stephen,Syngenta Limited; HANSEN, Genevieve,Syngenta Limited; HEIFETZ, Peter Bernard,Syngenta Limited |
The present invention relates to the expression of antibodies and/or fragments thereof in plants, and in particular to the expression of antibodies and/or fragments thereof that have specificity for enterotoxigenic Escherichia coli. Nucleotide and amino acid sequences of such antibodies and/or fragments are disclosed, as are methods of producing such antibodies and /or fragments, transgenic plants expressing such antibodies and/or fragments thereof, and methods of using such transgenic plants or material derived therefrom, in particular in the treatment or prevention of enteric disease. Also described are methods of enhancing the stability antibodies and fragments thereof. | ||||||
278 | PLANTS TRANSFORMED TO PRODUCE BACILLUS THURINGIENSIS INSECTICIDAL TOXINS | EP90902780.7 | 1990-02-14 | EP0458819B1 | 1994-01-12 | PEFEROEN, Marnix; LAMBERT, Bart; JOOS, Henk |
Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession nos. 5131 and 5132, produce crystal proteins during sporulation that are toxic to Coleoptera. The crystal proteins contain 74 kDa and 129 kDa protoxins, respectively, which can yield 67 and 66 kDa toxins, respectively, as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that codes for its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Coleoptera. | ||||||
279 | PLANTS TRANSFORMED TO PRODUCE BACILLUS THURINGIENSIS INSECTICIDAL TOXINS | EP90902780.0 | 1990-02-14 | EP0458819A1 | 1991-12-04 | PEFEROEN, Marnix; LAMBERT, Bart; JOOS, Henk |
Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession nos. 5131 and 5132, produce crystal proteins during sporulation that are toxic to Coleoptera. The crystal proteins contain 74 kDa and 129 kDa protoxins, respectively, which can yield 67 and 66 kDa toxins, respectively, as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that codes for its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Coleoptera. | ||||||
280 | Plastid transformation vectors for expressing proinsulin fused to the cholera toxin B-subunit in plants | EP08020922.4 | 2001-02-28 | EP2080803B1 | 2011-05-25 | Daniell, Henry |