ADVANCED DRUG DEVELOPMENT AND MANUFACTURING |
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| 申请号 | PCT/US2007021888 | 申请日 | 2007-10-10 | 公开(公告)号 | WO2008127291A2 | 公开(公告)日 | 2008-10-23 |
| 申请人 | LOS ALAMOS NAT SECURITY LLC; CALDERA PHARMACEUTICALS INC; BIRNBAUM EVA R; KOPPISCH ANDREW T; BALDWIN SHARON M; WARNER BENJAMIN P; MCCLESKEY MARK T; BERGER JENNIFER A; STEWART JEFFREY J; HARRIS MICHAEL N; BURRELL ANTHONY K; | 发明人 | BIRNBAUM EVA R; KOPPISCH ANDREW T; BALDWIN SHARON M; WARNER BENJAMIN P; MCCLESKEY MARK T; BERGER JENNIFER A; STEWART JEFFREY J; HARRIS MICHAEL N; BURRELL ANTHONY K; | ||||
| 摘要 | X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical, for estimating the binding selectivity of a chemical versus chemical analogs, for measuring post-translational modifications of proteins, and for drug manufacturing. | ||||||
| 权利要求 | |||||||
| 说明书全文 | |||||||
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