Thyroglobulin quantitation by mass spectroscopy |
|||||||
| 申请号 | US15443805 | 申请日 | 2017-02-27 | 公开(公告)号 | US09915663B2 | 公开(公告)日 | 2018-03-13 |
| 申请人 | Quest Diagnostics Investments Incorporated; | 发明人 | Yanni Zhang; Nigel J. Clarke; Richard E. Reitz; | ||||
| 摘要 | Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample. | ||||||
| 权利要求 | |||||||
| 说明书全文 | |||||||
QQ群二维码
意见反馈
意见反馈