TAMPERPROOF ORAL DOSAGE FORM |
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| 申请号 | US15769509 | 申请日 | 2016-08-08 | 公开(公告)号 | US20180303717A1 | 公开(公告)日 | 2018-10-25 |
| 申请人 | Capsugel Belgium NV; | 发明人 | Tom Huysmans; Tarryn Dierckx; Stefaan Jaak Vanquickenborne; | ||||
| 摘要 | A tamperproof dosage form for oral administration comprising: a caplet comprising first and second ends, a middle region extending between said first and second ends, parallel and oppositely disposed top and bottom faces, and a land interposed between the top and bottom faces and extending along a perimeter of the caplet on a plane parallel to a caplet length axis; and first and second shells, each comprising an open end and a closed dome-shaped end, each fitted over at least a portion of the caplet, the portion comprising at least the first and/or second ends of the caplet and at least part of the middle region. An adhesive substance being arranged between the caplet and the shells at least over a portion of the top and/or bottom faces proximal to the first and second ends of the caplet and a corresponding portion of an inner surface of the closed dome-shaped end of the shells to fixedly join the shells to the caplet. | ||||||
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