子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 161 | Affinity membrane system and method of using same | US668582 | 1996-06-20 | US5868936A | 1999-02-09 | Norma J. Ofsthun; Paul J. Soltys; Gretchen A. Kunas |
| The present invention provides an improved affinity membrane device and method for the effective removal of target molecules in plasma. The affinity membrane device is designed for use in an extracorporeal blood circuit and can be employed concurrently with other therapeutic processes for the purification of blood. The device of the present invention consists of hollow fiber membranes having specified dimensions and transfer properties, ligand immobilized to the pore surface of the hollow fibers, and a housing to encase the hollow fibers and allow appropriate entry and exit of the blood. In a preferred embodiment, specific immobilization chemistries are utilized to attach the ligands to the hollow fibers for optimal function. | ||||||
| 162 | Centrifugal adsorptive sample preparation device and method | US623688 | 1996-03-29 | US5833860A | 1998-11-10 | William Kopaciewicz; Ingeborg Cann; Donald G. Sheer |
| Adsorptive sample preparation device and method effective for concentrating, desalting and/or purifying biomolecules. An adsorptive membrane is used to bind biomolecules, which biomolecules can then be eluted with a suitable desorption agent. In a preferred form, the adsorptive filter means is a particle-laden semipermeable membrane having at least one of its major surfaces, preferably both of its major surfaces, covered with a thin fabric. In the method of the invention for concentrating biomolecules or desalting or purify from a solution, the sample reservoir of the above-described adsorptive sample preparation device is filled with an analyte solution, placed in a fixed angle or swinging bucket centrifuge rotor, the solution is driven through the membrane, and analyte obtained as a result of adsorption on the membrane is recovered by washing and then eluting with a suitable desorption agent. A method of sealing the membrane in the device is also set forth. | ||||||
| 163 | Methods and apparatus using hydrogels | US591139 | 1996-01-25 | US5770086A | 1998-06-23 | Andris Indriksons; Patricia C. Andrews |
| The hydrogel-forming polymers are used as absorbents for collecting and concentrating solutions. A solution to be concentrated can be contained in a dialysis membrane, with the hydrogel-forming polymer, or mixture thereof, on the outer surface of the membrane. A hydrogel-forming polymer can be added directly to the solution to be concentrated and the resulting concentrate separated from the gel by filtration of decanting. A hydrogel-forming polymer can be placed in a container formed of porous material and the container can be added to the solution to be concentrated and physically removed after concentration has occurred. Hydrogel-forming polymer can be used as a liquid collection in diagnostic membrane assay cartridges. | ||||||
| 164 | Membrane affinity apparatus and purification methods related thereto | US465479 | 1995-06-05 | US5683916A | 1997-11-04 | Randal A. Goffe; Stephen E. Zale; James L. O'Connor; Stephen B. Kessler |
| A method and apparatus for carrying out affinity purification of a ligate. The method comprising, (a) providing a ligate containing liquid to a first side of at least one porous hollow fiber membrane with a ligand immobilized thereto that binds and separates the ligate from the liquid, (b) withdrawing a first portion of the liquid from the first side of the porous hollow fiber membrane, (c) recirculating the first portion of liquid to the first side of the porous hollow fiber membrane, (d) repeating steps (a) to (c) until a majority of the liquid has flowed through the porous hollow fiber membrane, and (e) providing an elution solution to one side of the porous hollow fiber membrane under a pressure sufficient to cause the elution solution to flow into and through the membrane to effect disassociation of any ligate-ligand bonds wherein any ligate bound to the ligand is eluted with the elution solution. | ||||||
| 165 | Concentration of pesticides by membrane perstraction | US396511 | 1995-03-01 | US5639375A | 1997-06-17 | Nomura Hiroshi |
| Disclosed is a method for concentrating by 20 to 10,000 fold a semivolatile or essentially nonvolatile organic compound, such as a herbicide or pesticide, from a contaminated aqueous solution into a carrier fluid for simultaneous or subsequent analysis. A perstraction membrane is contacted on one surface with a large volume of an aqueous feedstream containing a low concentration of an organic compound, and an opposite surface of the same membrane is contacted with a small volume of a carrier fluid. The perstraction membrane is characterized by a nonporous layer therein which precludes convective flow and mixing between the aqueous and carrier fluid phases. The organic compound is absorbed into the nonporous skin layer from the aqueous fluid and is transferred from the nonporous skin layer into the carrier fluid by an affinity driving force, the affinity of the carrier fluid for the organic compound being greater than the affinity of water for the same compound. The carrier fluid containing the organic compound in concentrated form is passed through a flow cell of an analytical instrument for detection and analysis, or is presented to a sampling port of an analytical instrument, or is otherwise sampled for analysis in a subsequent operation. | ||||||
| 166 | Ozone water treatment method and apparatus | US285698 | 1994-08-04 | US5626769A | 1997-05-06 | Isao Sawamoto |
| There are provided an ozone water treatment method by comprising the steps of injecting an ozone-containing gas into pure water to prepare ozone water, supplying the ozone water to use point(s) for treatment of materials to be treated, and circulating for reuse or discharging the ozone water after use, which comprises disposing a deozonizing apparatus, the inside of which is divided into an ozone water passing zone and a reduced pressure zone by a diaphragm, at the downstream side of the use point(s), supplying the ozone water after use to the ozone water passing zone of the deozonizing apparatus, and removing residual ozone and residual oxygen in the ozone water after use by contacting the water with the reduced pressure zone through the diaphragm and an apparatus utilized in the ozone treatment method. | ||||||
| 167 | Membrane deaerator apparatus | US381863 | 1995-02-07 | US5584914A | 1996-12-17 | Yasutoshi Senoo; Hitoshi Shiraishi; Norio Yasu; Yasuhiro Kawakami; Yukinori Tobisaka; Yasuo Ochi; Yasuhito Mitsukami; Toshitaka Shigematsu; Kazuhiro Tachino; Yasuhiro Miyagama; Kenichiro Takematsu; Nobuaki Yanagihara |
| The membrane deaerator according to the present invention includes a plurality of membrane deaerator modules and a water sealed vacuum pump connected thereto. These modules are series-connected between a raw water supply line and a deaeration water supply line. A first vacuum pump is connected to a first deaerator module via a deaeration line, and a second vacuum pump is connected to a second deaerator module via the deaeration line. These vacuum pumps are each provided with a seal water supply line which is used to send the raw water introduced from the water supply line thereinto as seal water to each of the first and second vacuum pumps. A discharge line for the second vacuum pump is connected to the deaeration line for the first vacuum pump. In the membrane deaerator thus formed, the deaeration performance is improved greatly, and a deaeration with dissolved oxygen concentration of several PPB can be carried out. | ||||||
| 168 | Method for deaerating liquid products | US298619 | 1994-08-31 | US5522917A | 1996-06-04 | Katsuhisa Honda; Masazumi Yamashita |
| A deaeration method for eliminating dissolved gases from a liquid product, which method involves low initial cost and running cost, compact equipment, and simple arrangement to accomplish the deaeration. For the method to eliminate dissolved gases from a liquid product, a deaeration module which is divided by a gas-pervious membrane into a liquid phase side and a vapor phase side is used. A deaeration-use gas composed of one or more kinds of inactive gases is previously dissolved in a liquid product to be deaerated, whereby a deaeration-target liquid is prepared. The deaeration-target liquid is distributed on the liquid phase side, in which distribution process the deaeration-use gas moves to the vapor phase side via the gas-pervious membrane, while the dissolved gases move to the vapor phase side along with the movement of the deaeration-use gas. This movement of the gases is carried out during passage through the deaeration module under ambient pressure. | ||||||
| 169 | Method of deodorizing a formulation containing at least one compound bearing a thiol group and deodorized formulation thus obtained | US235462 | 1994-04-29 | US5458848A | 1995-10-17 | Herve Burgaud |
| Method of deodorizing in order to remove malodorous compounds which are present in or formed from a liquid formulation containing at least one compound bearing a thiol functional group, of formula:HS--A--Y--B (I)in which:1) the liquid formulation is placed in contact with an inert membrane which is permeable to the malodorous compounds and impermeable to the compound(s) of formula (I); and2) the malodorous compounds which have passed through the membrane are placed in contact with at least one chemical substance reacting with the said malodorous compounds and/or with at least one physical adsorption substance having a large specific surface area which binds the said malodorous compounds. | ||||||
| 170 | Method for recycling cleaning fluid | US210353 | 1994-03-18 | US5456842A | 1995-10-10 | Harry Kibblehouse; Michael Presley; Jared Finney; Harvey Grace |
| A method and apparatus for recycling water based workpart cleaning fluid of the type used to wash workparts (B) free of soils, such as emulsified and non-emulsified cutting oils and lubricants, particulate matter and other hydrophobic fluids. A parts washer (12) is provided for cleaning workparts (B) contaminated with soils. The contaminated cleaning fluid is discharged from the parts washer (12) in a slip stream and directed to a process tank (22). The contaminated cleaning fluid is pumped from the process tank (22) to a prefilter (28) where large particles are screened. The cleaning fluid is then directed to regenerated cellulose membrane filters (34) where the water based cleaning fluid and the hydrophilic water soluble substances in the base, i.e., the detergents, are imbibed through the membrane (34) as permeate while the soils pass as retentate. The permeate is returned to the parts washer (12), whereas the retentate is directed back to the process tank (22). | ||||||
| 171 | Recovery plant for surplus water paint | US9562 | 1993-01-26 | US5443738A | 1995-08-22 | Satpal Bhatnagar; Hans-Ulrich Frey; Juergen Weschke |
| To provide a recovery plant for surplus water paint in paint-spraying booths comprising a circuit of water circulating in the booth, wherein such problems with sedimenting water paint particles no longer arise, it is proposed that a volume flow of water circulating in the booth flow from the circuit of water circulating in the booth through a branch pipe to a preconcentration stage, that the preconcentration stage comprise a ring circuit with an ultrafiltration unit for continuously producing a preconcentrate in the ring circuit and a permeate which leaves the ring circuit, that the permeate flow into the circuit of water circulating in the booth and the preconcentrate into a final concentration stage, that the final concentration stage comprise a ring circuit with an ultrafiltration unit which increases the concentration of the preconcentrate in batches to the final concentrate and produces a permeate which flows into the circuit of water circulating in the booth. | ||||||
| 172 | Microporous polysulfone supports suitable for removal of low density lipoprotein-cholesterol | US95617 | 1993-07-21 | US5418061A | 1995-05-23 | Marc E. Parham; Richard L. Duffy |
| The present invention relates to the efficient removal of low density lipoprotein cholesterol complex (LDL-C) from whole blood. More specifically, it relates to a microporous plasmapheresis support having an immobilized affinity agent. The immobilized affinity agent is polyacrylic acid bound directly and/or through an interaction with silica and/or calcium chloride to a microporous polysulfone support. | ||||||
| 173 | Device for the removal and concentration of organic compounds from the atmosphere | US87374 | 1993-07-08 | US5395426A | 1995-03-07 | James N. Huckins; Jimmie D. Petty; James A. Zajicek; Virginia L. Gibson |
| A device and method for removing, concentrating and analyzing airborne organic compounds. The device includes a nonporous membrane which contains a collection media. The liquid collection media typically includes a component which has a molecular weight that is too large to pass through transport corridors in the nonporous membrane and a component which has a molecular weight which is sufficiently small enough to pass through the transport corridors in the nonporous membrane and thereby forming a thin film on the exterior surface of the device. The collection media can consist of only components too large to pass through the membrane transport corridors. Organic contaminants are trapped in the thin film on the exterior surface of the device or the membrane and transported by concentration gradient diffusion forces into the bulk of the collection media within the nonporous membrane. | ||||||
| 174 | Method for preparing membranes with adjustable separation performance | US135223 | 1993-10-13 | US5385672A | 1995-01-31 | Eric S. Peterson; Christopher J. Orme; Mark L. Stone |
| Methods for adjustable separation of solutes and solvents involve the combination of the use of a maximally swollen membrane and subsequent vacuum depressurization exerted on the permeate side of that membrane. By adjusting the extent of depressurization it is possible to separate solvent from solutes and solutes from each other. Improved control of separation parameters as well as improved flux rates characterize the present invention. | ||||||
| 175 | Process for at least partial dehydration of an aqueous composition and devices for implementing the process | US964220 | 1992-10-21 | US5382365A | 1995-01-17 | Philippe Deblay |
| The present invention relates to a process for at least partial dehydration of an aqueous composition, in which said composition to be dehydrated is brought into contact, through the intermediacy of a microporous hydrophobic membrane, with a receiving phase whose water activity is substantially lower than that of the aqueous composition and in which the aqueous composition, at least partially dehydrated, is recovered. The invention also relates to devices enabling the process to be implemented, especially continuously. | ||||||
| 176 | Hydraulic reservoir with gas/oil separator | US45602 | 1993-04-09 | US5326386A | 1994-07-05 | Leung Lee; James J. Pavlica |
| A reservoir for use in a hydraulic circuit is disclosed which includes a passive gas separating medium to separate gas from the hydraulic fluid as it circulates through the reservoir. The gas separating medium, which may be a membrane-type diffuser, is permeable to air, but not hydraulic fluid. This allows entrained air to diffuse through the membrane element after which it may be expelled to the atmosphere. The membrane diffuser is located within the reservoir housing in a low-pressure portion of the hydraulic circuit in a space between spaced apart double walls of the reservoir such that hydraulic fluid returning to the reservoir must first pass through the membrane. The membrane may have several concentric or spiral layers, depending upon the capacity of the circuit. Gas separated from the hydraulic fluid is withdrawn from the membrane diffuser structure and may be vented to atmosphere through a valve associated with the reservoir housing. | ||||||
| 177 | Device and method for extracorporeal blood treatment | US832080 | 1992-02-06 | US5277820A | 1994-01-11 | Stephen R. Ash |
| Disclosed are preferred devices and methods which provide extracorporeal treatment of blood to effectively and consistently remove toxins therefrom and from patients over extended periods of time. | ||||||
| 178 | Apparatus and method for reversed permeation membrane extraction of compounds from sample solutions | US893874 | 1992-06-05 | US5221477A | 1993-06-22 | Richard G. Melcher; Paul J. O'Connor |
| A reversed permeation membrane assembly and method for collecting one or more compounds of interest from a sample solution. The membrane assembly includes a semi-permeable membrane of predetermined thickness and length, and having inner and outer surfaces. The membrane is attached adjacent its outer surface to a substantially rigid membrane support, and a non-porous barrier contacts the outer surface of the membrane to prevent permeation of compounds beyond the outer surface in use. In a preferred embodiment, the semi-permeable membrane assumes a substantially tubular conformation through which sample solution may be passed. The membrane support also preferably features a tubular conformation within which the semi-permeable membrane is mounted. Because of its unique structure and improved efficiency, the assembly of the present invention may be incorporated for in-line use with liquid and gas chromatography devices and GC/MS units. In some applications, the extractant can even be flowed through the membrane cell to collect analytes and directly to an LC column for analysis in a substantially non-stop manner. | ||||||
| 179 | Spiral wound gas permeable membrane module and apparatus and method for using the same | US660443 | 1991-02-26 | US5154832A | 1992-10-13 | Hiroyuki Yamamura; Hiroyuki Ikada; Yukuo Toyoda; Kazuhiko Nishimura; Kazuo Imai |
| A spiral wound gas permeable membrane module having a hollow mandrel with a plurality of holes, at least one envelope-like gas permeable membrane wrapped spirally around the mandrel, at least one feed water spacer positioned on the outer surfaces of the spirally wrapped envelope-like membrane, and at least one permeation side spacer provided in the envelope-like membrane. The module contains a partition block for blocking the flow of a gas flowing in the mandrel in its longitudinal direction and a flow regulating wall directing the flow of the gas introduced into the envelope-like membrane through the holes aligned on one side of the partition block so that the gas travels in the envelope-like membrane in a spirally outer direction, then returns in a spiral inner direction and flows into the mandrel through the holes aligned on the other side of the partition block. The gas dissolved in raw water supplied to the feed water spacer side is degasified by gas permeation to the permeation side spacer through the membrane which has a broad area for permeation with a high efficiency. | ||||||
| 180 | Hollow fiber bundle element | US618424 | 1990-11-27 | US5139668A | 1992-08-18 | Chuen Y. Pan; Curtis W. McMinis |
| A hollow fiber bundle element comprises a bundle of microporous hollow fibers disposed in a cylindrical impermeable casing. Each fiber, wall provide a permeability in the microfiltration range (0.05 to 5 micrometers). The bundle forms two longitudinal passageways, being the lumina of the fibers and the other being the void space between the fibers. A first of these passageways is densely and uniformly packed with minute solid particles. No binder is used to fix the particles--they maintain their distribution in the passageway as a result of having been densely packed under pressure. The ends of the first passageway are sealed, and since the fiber wall pores are smaller than the particles, the particles are immobilized therein. The hollow fiber module packed with minute adsorbent particles in the first passageway provides an adsorber. A fluid mixture comprising a carrier and an adsorbate is introduced into the second passageway, and diffuses through the fiber walls and is collected by the adsorbent particles. The use of small adsorbent particles enhances adsorption rate, and availability of a separate longitudinal flow passageway reduces pressure drop across the adsorber. Alternatively, the hollow fiber module may be packed with minute catalyst particles to provide an effective catalytic reactor with improved mass transfer between the catalyst particles in the first passageway and surrounding fluid containing the reactants, in the second passageway. | ||||||
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