序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
61 Adjustable support for tubular medical device processing US14949377 2015-11-23 US09724717B2 2017-08-08 Adam K. Hoopai
An apparatus and method for supporting a tubular medical device, such as a stent or scaffold, includes a rod disposed between two collets. The rod can be shaped to form a range of different size or length helical supports to support a wide range of tubular medical devices. The rod is shaped into a full or partial helix by rotating one of the collets relative to the other.
62 Medical device coatings for releasing a therapeutic agent at multiple rates US14564604 2014-12-09 US09656003B2 2017-05-23 William F. Moore; Gary Bradford Shirley
Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodiment, medical device coatings are provided having a higher concentration of the therapeutic agent in a first region of the coating than in a second region of the coating. In a third embodiment, medical device coatings are provided that are formed by certain coating processes wherein the droplet size of a spray coating solution is changed during the coating process. These coating processes preferably include applying a solution comprising a therapeutic agent and a suitable solvent to a surface of an implantable medical device. In a fourth embodiment, methods of treatment are provided that include implanting a coated medical device.
63 BIODEGRADABLE VASCULAR FILTER US15291681 2016-10-12 US20170105830A1 2017-04-20 Kasper KLAUSEN
A vascular filter includes filtration struts formed between a hub and a supporting stent structure including stent struts. The hub and the filtration basket are formed from a material that is more biodegradable that the material from which the supporting stent structure is formed. The vascular filter is laser cut from an intermediate tube.
64 Embolic protection devices having short landing zones US13400424 2012-02-20 US09572650B2 2017-02-21 Richard S. Kusleika; Steven G. Zaver; Christopher G. Quinn
The invention provides an embolic protection device for removing emboli from a blood vessel in a patient's body. The device comprises an elongate host element, an embolic protection element having a collapsed configuration and an expanded configuration, and a flexible tether connected to a distal end of the host element and to a proximal portion of the embolic protection element. The tether allows the host element to move axially and laterally relative to the embolic protection element over a limited range of motion when the embolic protection element is in an expanded configuration. The embolic protection device has a landing zone of 4 cm or less.
65 Time-dependent polymer scaffolds US13842432 2013-03-15 US09517150B2 2016-12-13 Syed Hossainy; Mikael Trollsas; Michael Huy Ngo; Erik David Eli
A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
66 Apparatus for attaching radiopaque markers to a stent US14584431 2014-12-29 US09452067B2 2016-09-27 Patrick P. Wu
A mandrel for supporting a stent and rollers for pressing a radiopaque marker into a stent are disclosed. The mandrel can have a forward portion for carrying the stent and a rear portion for urging the stent forward portion into a gap between the rollers. The mandrel may be pushed or pulled into the gap, which is sized to allow the rollers to press the marker into engagement with the stent. Prior to moving the mandrel into the gap, the marker may be placed on a surface of the stent or partially inside a recess in the stent. Several markers can be efficiently and uniformly pressed onto the stent by moving the mandrel into the gap in one continuous movement in an axial or lateral direction. Markers can also be pressed onto the stent by placing the stent in the gap and rotating the stent about its central axis.
67 Stent And Filter US15053970 2016-02-25 US20160242893A1 2016-08-25 Kaushik Joshi; Matthew J. Fitz
A stent utilizing an integral filter is described. The filter portion of the stent can be connected directly to the end of the stent or can be space apart via a plurality of struts. The filter stent can be used to catch embolic material and/or the filter portion can be filled with embolic material (e.g., embolic coils) for the purpose of occluding a vessel.
68 SYSTEM AND METHOD FOR ATTACHING A RADIOPAQUE MARKER BEAD TO AN ENDOPROSTHESIS US14629669 2015-02-24 US20160242851A1 2016-08-25 Rommel Lumauig
A radiopaque marker bead can be attached to an endoprosthesis by pressing an end of bead into a through hole formed into the endoprosthesis and allowing the opposite end of the bead to pass through the hole and protrude out of the other end of the hole. Both ends of the bead can then be pressed and flattened so as to frictionally engage both ends of the hole. A support tool having a curved outer surface can be inserted into the endoprosthesis to support the endoprosthesis luminal surface while the bead is being pushed into the hole. The support tool has a depression which allows the opposite end of the bead to protrude out of the hole.
69 HEAT-TREATED BRAIDED INTRAVASCULAR DEVICES AND METHODS US14879167 2015-10-09 US20160081825A1 2016-03-24 Yuri SUDIN; Ronen ECKHOUSE; Aharon FRIEDMAN
A process for making a product including an expandable member is provided. The process can include braiding a plurality of wires to form a tubular structure that is capable of being manipulated such that a region of the tubular structure changes in diameter from a first dimension to a second dimension different from the first dimension. The process can also include initially heat-treating the tubular structure while the region is in the first dimension, changing the diameter of the tubular structure such that the region achieves the second dimension, and subsequently heat-treating the tubular structure while the region is in the second dimension.
70 MEDICAL CONSTRUCTS INCLUDING TUBES AND COLLAGEN FIBERS US14875202 2015-10-05 US20160022874A1 2016-01-28 Leon Paulos; Mengyan Li; Daniel Hernandez; Thomas Koob
Medical constructs with collagen fibers and gelatin and related collagen fibers. The collagen fibers can be derived from extruded soluble dermal collagen and can include a gelatin film attached to the at least one collagen fiber. The gelatin film can include one or more minerals and has a gelatin concentration of between about 0.1% to about 40% weight per volume.
71 LASER TUBE CUTTER WITH IN-SITU MEASURING AND SORTING US14801627 2015-07-16 US20160016273A1 2016-01-21 Andrew Honegger; Andrew Phillip; Onik Bhattacharyya; Kyle Stacy; Grzegorz Nowobilski; Kamil Szczepanik
A laser tube-cutting machine is disclosed. The tube-cutting machine may include a processing station where raw material enter the machine, a holding and positioning station configured to hold and position the raw material, at least one combined measurement and laser cutting station including a laser and at least one sensor configured to measure various aspects of the tube both before and after cutting, and an outflow processing station where cut material exit the machine.
72 Systems and Methods for Ligament Graft Preparation US14327358 2014-07-09 US20160008123A1 2016-01-14 Scott A. Woodruff; Mehmet Z. Sengun
Systems and methods for preparing a ligament graft for a ligament reconstruction procedure are provided. In general, the described techniques utilize a graft preparation system having a holder and a delivery suture assembly removably coupled thereto. The delivery suture assembly can include a spine coupled with an anchor suture configured to form a self-tightening knot used to position the assembly around a graft and a plurality of suture windings configured to be affixed to the graft when the assembly is deployed. The assembly is delivered to the graft using the holder and the sutures can be affixed to the graft without penetrating therethrough. The spine helps to evenly distribute the load among the windings compressing the graft which are thus are capable of withstanding increased loads. Thus, an improved, simplified, and time- and labor-saving approach to preparing ligament grafts is provided.
73 MOBILE BIO-SCAFFOLD CONTROLLED BY MAGNETIC FIELD AND METHOD OF MANUFACTURING THE SAME US14735967 2015-06-10 US20150351897A1 2015-12-10 Hong Soo CHOI; Sang Won KIM; Seung Min LEE
A mobile bio-scaffold controlled by a magnetic field is provided. A mobile bio-scaffold controlled by a magnetic field according to the present invention comprises a spherical body including a first ring, a second ring connected to the first ring that intersects the second ring, and a third ring connected to the first and second rings that intersect the third ring, with a plurality of openings being defined by the first to third rings. A magnetic layer is disposed on the spherical body. The spherical body rotates through interaction between the magnetic layer and a rotational magnetic field applied from an external source, thereby moving by rolling in a single direction.
74 Adjustable support for tubular medical device processing US13273133 2011-10-13 US09199261B2 2015-12-01 Adam K. Hoopai
An apparatus and method for supporting a tubular medical device, such as a stent or scaffold, includes a rod disposed between two collets. The rod can be shaped to form a range of different size or length helical supports to support a wide range of tubular medical devices. The rod is shaped into a full or partial helix by rotating one of the collets relative to the other.
75 METHODS OF MAKING COLLAGEN FIBER MEDICAL CONSTRUCTS AND RELATED MEDICAL CONSTRUCTS, INCLUDING NERVE GUIDES AND PATCHES US14734548 2015-06-09 US20150283305A1 2015-10-08 Mengyan Li; Thomas J. Koob
The disclosure describes methods of winding collagen fiber to make medical constructs and related collagen fiber tube and patch devices.
76 MANUFACTURING AN ARTICULATING OPHTHALMIC SURGICAL PROBE US14612576 2015-02-03 US20150223976A1 2015-08-13 DUSTIN J. BOUCH; RAFFI S. PINEDJIAN; TIMOTHY C. RYAN
A method of manufacturing an articulating ophthalmic surgical probe includes providing a cannula having an outer diameter of 20 Ga or less and a slotted tip, permanently attaching a pull wire to the slotted tip, permanently attaching a metal anchor to a distal end of the pull wire, positioning a weld pin within a handle assembly that is sized to fit within a single hand, and welding the metal anchor to the weld pin within the handle assembly.
77 CUP FOR AN ORTHOPAEDIC IMPLANT, ORTHOPAEDIC IMPLANT COMPRISING SUCH A CUP AND METHOD FOR PRODUCING SUCH A CUP US14378967 2013-02-19 US20150012109A1 2015-01-08 Pierre-Etienne Moreau; Thibault Loriot De Rouvray; Thomas Brosset; Julien Dumas; Jean-Michel Delobelle; Henri-Paul Prudent; Jean-François Bataille; Bertrand Blandet
A cup having an inner cavity, for an articulation organ, and a metallic outer layer and in a portion of a spheroid, the outer layer including networks of meshes with nodes and struts, where the struts are tapered struts each having a tapered shape and being arranged such that the tapered shapes are uniformly oriented.
78 INTERVENTIONAL MEDICAL DEVICE AND MANUFACTURING METHOD THEREOF US14348815 2012-01-17 US20150004207A1 2015-01-01 Xu Cai; Dadong Zhang; Yan Hu; Peng Huang; Junfei Li; Chengyun Yue; Zhirong Tang; Qiyi Luo
An interventional medical device and manufacturing method thereof, the interventional medical device comprising a stent body (1); the stent body (1) is provided with a drug releasing structure on the surface, the drug in the drug releasing structure being a drug for inhibiting adventitial fibroblast proliferation. When the interventional medical device is implanted into a human body, the drug for inhibiting the adventitial fibroblast proliferation can be slowly released into vessel wall cells in contact with the stent body (1), thus inhibiting the proliferation of the adventitial fibroblasts, promoting vascular compensatory expansion, and reducing the incidence rate of instent restenosis.
79 METHODS FOR VASCULAR RESTORATION THERAPY US13842547 2013-03-15 US20140114399A1 2014-04-24 Syed HOSSAINY; Chad J. ABUNASSAR; Michael Huy NGO; Erik David ELI; Santosh V. PRABHU; Mikael TROLLSAS; Richard RAPOZA
A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
80 TIME-DEPENDENT POLYMER SCAFFOLDS US13842432 2013-03-15 US20140114398A1 2014-04-24 Syed HOSSAINY; Mikael TROLLSAS; Michael Huy NGO; Erik David ELI
A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
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