| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 241 | Optical material and method for modifying the refractive index | US11948298 | 2007-11-30 | US07789910B2 | 2010-09-07 | Wayne H. Knox; Li Ding; Jay F. Kunzler; Dharmendra Jani; Candido D. Pinto |
| A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. | ||||||
| 242 | Apparatus and method of correcting higher-order aberrations of the human eye | US11869607 | 2007-10-09 | US07695134B2 | 2010-04-13 | Andreas W. Dreher; Shui T. Lai; Donald G. Bruns |
| The wavefront aberrator is applicable to correct aberrations of the human eye. In one embodiment, the aberrator device comprises a pair of transparent lenses separated by a layer of curable resin comprising monomers and polymerization initiators. By controlling the extent of its curing, this monomer layer provides an adjustable index of refraction profile across the layer. Curing of the resin may be made by exposure to light, such as ultraviolet light. By controlling the extent of light exposure across the surface of the curable resin, for example, a particular and unique refractive index profile can be produced. | ||||||
| 243 | LASER MODIFICATION OF INTRAOCULAR LENS | US12239462 | 2008-09-26 | US20100082017A1 | 2010-04-01 | Leander Zickler; Jim Deacon |
| A system of modifying an intraocular device located within an eye, wherein the system includes a laser assembly and a controller coupled to the laser assembly. The laser assembly outputs a pulsed laser beam having a pulse width between about 300 picoseconds and about 10 femtoseconds, and the controller directs the laser assembly to output the pulsed laser beam into the intraocular device. One or more slip zones are formed within the intraocular device in response thereto, and the slip zones are configured to modify a refractive profile of the intraocular device. A method of modifying a refractive profile of an eye having an intraocular device implanted therein, wherein the method includes determining a corrected refractive profile for the eye based on an initial refractive profile, identifying one or more locations within the intraocular device based on the corrected refractive profile, and directing a pulsed laser beam at the locations to produce the corrected refractive profile. | ||||||
| 244 | Optical hydrogel material with photosensitizer and method for modifying the refractive index | US12380892 | 2009-03-04 | US20090287306A1 | 2009-11-19 | Thomas Smith; Wayne H. Knox; Li Ding; Dharmendra Jani; Jeffrey G. Linhardt |
| A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures. | ||||||
| 245 | Two-photon absorption decolorizable material, two-photon absorption refractive index modulation material, two-photon absorption polymerization material, two-photon absorption polymerization method and three-dimensional optical recording material | US11219737 | 2005-09-07 | US07582391B2 | 2009-09-01 | Hiroo Takizawa |
| A two-photon absorption decolorizable material comprising: a two-photon absorption dye executing a two-photon absorption; and a decolorizable dye having a molar absorption coefficient equal to or less than 100 at a wavelength of a light irradiated at the two-photon absorption, wherein the decolorizable dye is decolorized by an electron transfer or an energy transfer utilizing an excitation energy obtained by the two-photon absorption of the two-photon absorption dye. | ||||||
| 246 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX | US11948298 | 2007-11-30 | US20090143858A1 | 2009-06-04 | Wayne H. Knox; Li Ding; Jay F. Kunzler; Dharmendra Jani; Candido D. Pinto |
| A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. | ||||||
| 247 | APPARATUS AND METHOD OF CORRECTING HIGHER-ORDER ABERRATIONS OF THE HUMAN EYE | US11869607 | 2007-10-09 | US20080252845A1 | 2008-10-16 | Andreas W. DREHER; Shui T. LAI; Donald G. BRUNS |
| The wavefront aberrator is applicable to correct aberrations of the human eye. In one embodiment, the aberrator device comprises a pair of transparent lenses separated by a layer of curable resin comprising monomers and polymerization initiators. By controlling the extent of its curing, this monomer layer provides an adjustable index of refraction profile across the layer. Curing of the resin may be made by exposure to light, such as ultraviolet light. By controlling the extent of light exposure across the surface of the curable resin, for example, a particular and unique refractive index profile can be produced. | ||||||
| 248 | VISION IN MACULAR DEGENERATION PATIENTS | US12048169 | 2008-03-13 | US20080218688A1 | 2008-09-11 | Andreas W. Dreher |
| An eyeglass lens and manufacturing method using a variable refractive index material, such as epoxy. In one embodiment, a method of making an eyeglass lens includes: imaging a patient's eye to determine a wavefront prescription for the patient; and curing the lens based on the wavefront prescription such that the wavefront guided lens corrects for aberrations over the lens for a plurality of gazing angles of the patient. | ||||||
| 249 | APPARATUS AND METHOD OF FABRICATING AN OPHTHALMIC LENS FOR WAVEFRONT CORRECTION USING SPATIALLY LOCALIZED CURING OF PHOTO-POLYMERIZATION MATERIALS | US12027907 | 2008-02-07 | US20080123197A1 | 2008-05-29 | Shui T. LAI |
| A method for making an optical compensating element for, e.g., correcting aberrations in human vision or other applications. A curable material is held between two plates, and based on the aberrations sought to be corrected, a desired curing contour is determined to establish a line below which a predetermined index of refraction will be obtained. A light beam is focused along the line to cure material along the line. Uncured material above the line can be removed and uncured material below the line then cured in bulk, to speed the manufacturing process. | ||||||
| 250 | Monomers and polymers for optical elements | US10936030 | 2004-09-07 | US07371804B2 | 2008-05-13 | Jagdish Jethmalani; Andreas W. Dreher; Gomaa Abdel-Sadek; Jeffrey Chomyn; Jieming Li; Maher Qaddoura |
| Compositions comprising a matrix polymer and a mixture of monomers are used for making polymer mixtures containing the matrix polymer and a second polymer formed from the monomer mixture. Preferably, the matrix polymer comprises a polyester, polystyrene, polyacrylate, thiol-cured epoxy polymer, thiol-cured isocyanate polymer, or mixtures thereof. Preferably, the monomer mixture comprises a thiol monomer and at least one second monomer selected from the group consisting of ene monomer and yne monomer. The compositions may be used to fabricate optical elements such as lenses. | ||||||
| 251 | APPARATUS AND METHOD OF FABRICATING A COMPENSATING ELEMENT FOR WAVEFRONT CORRECTION USING SPATIALLY LOCALIZED CURING OF RESIN MIXTURES | US11749058 | 2007-05-15 | US20080088938A1 | 2008-04-17 | Shui LAI |
| An optical wavefront correction plate incorporates a unique, three-dimensional spatial retardation distribution utilizing the index of refraction change of resin mixture in its cured state. The optical wave plate comprises a pair of transparent plates, containing a layer of a monomers and polymerization initiators, such as resin mixture. This resin mixture exhibits a variable index of refraction as a function of the extent of its curing. Curing of the resin mixture may be made by exposure to light, such as ultraviolet light, and may be varied across and through the surface of the resin mixture to create a particular and unique three-dimensional wavefront retardation profile. The optical wave plate provides improved performance in large area mirrors, lenses, telescopes, microscopes, and ophthalmic diagnostic systems. | ||||||
| 252 | Light Adjustable Multifocal Lenses | US11871574 | 2007-10-12 | US20080086207A1 | 2008-04-10 | Christian Sandstedt; Jagdish Jethmalani; Shiao Chang |
| The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses. | ||||||
| 253 | MONOMERS AND POLYMERS FOR OPTICAL ELEMENTS | US11935989 | 2007-11-06 | US20080068723A1 | 2008-03-20 | Jagdish JETHMALANI; Andreas Dreher; Gomaa Abdel-Sadek; Jeffrey Chomyn; Jieming Li; Maher Qaddoura |
| An optical element includes a first lens; a cover; and a cured matrix polymer sandwiched between the first lens and the cover; the matrix polymer, prior to curing, having a monomer mixture dispersed therein; the matrix polymer being selected from the group consisting of polyester, polystyrene, polyacrylate, thiol-cured epoxy polymer, thiol-cured isocyanate polymer, and mixtures thereof; and the monomer mixture comprising a thiol monomer and at least one second monomer selected from the group consisting of ene monomer and yne monomer. | ||||||
| 254 | Method for improved retinal safety using the light adjustable lens (LAL) | US11493358 | 2006-07-26 | US20080027537A1 | 2008-01-31 | Mario Gerlach; Christian A. Sandstedt; Shiao H. Chang |
| Embodiments of the invention involve intraocular lenses that are light adjustable to change a focal length of the lens after it has been implanted into a person or animal. The lens includes a layer of UV absorbent material located on a rear side, which is the side facing a retina. The lens may comprise a UV reducing rim that surrounds a peripheral portion of the lens, and reduces or blocks UV light from striking the retina. | ||||||
| 255 | Eyeglass manufacturing method using variable index layer | US11703855 | 2007-02-07 | US20070171359A1 | 2007-07-26 | Andreas Dreher |
| An eyeglass lens and manufacturing method using a variable refractive index material, such as epoxy. In one embodiment, a method of making an eyeglass lens includes: imaging a patient's eye to determine a wavefront prescription for the patient; and curing the lens based on the wavefront prescription such that the wavefront guided lens corrects for aberrations over the lens for a plurality of gazing angles of the patient. | ||||||
| 256 | Eyeglass manufacturing method using variable index layer | US11649995 | 2007-01-05 | US20070109494A1 | 2007-05-17 | Andreas Dreher |
| An eyeglass lens and manufacturing method using a variable refractive index material, such as epoxy. In one embodiment, a method of making an eyeglass lens includes: imaging a patient's eye to determine a wavefront prescription for the patient; and curing the lens based on the wavefront prescription such that the wavefront guided lens corrects for aberrations over the lens for a plurality of gazing angles of the patient. | ||||||
| 257 | Apparatus and method of fabricating a compensating element for wavefront correction using spatially localized curing of resin mixtures | US10265517 | 2002-10-03 | US07217375B2 | 2007-05-15 | Shui T. Lai |
| An optical wavefront correction plate incorporates a unique, three-dimensional spatial retardation distribution utilizing the index of refraction change of resin mixture in its cured state. The optical wave plate comprises a pair of transparent plates, containing a layer of a monomers and polymerization initiators, such as resin mixture. This resin mixture exhibits a variable index of refraction as a function of the extent of its curing. Curing of the resin mixture may be made by exposure to light, such as ultraviolet light, and may be varied across and through the surface of the resin mixture to create a particular and unique three-dimensional wavefront retardation profile. The optical wave plate provides improved performance in large area mirrors, lenses, telescopes, microscopes, and ophthalmic diagnostic systems. | ||||||
| 258 | Lenses capable of post-fabrication power modification | US10175552 | 2002-06-18 | US07210783B2 | 2007-05-01 | Jagdish M. Jethmalani; Daniel M. Schwartz; Julia A. Kornfield; Robert H. Grubbs; Christian A. Sandstedt |
| The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively. | ||||||
| 259 | Delivery system for post-operative power adjustment of adjustable lens | US11114861 | 2005-04-25 | US07105110B2 | 2006-09-12 | Ben C. Platt; Christian A. Sandstedt; James A. Ebel |
| A method and instrument to irradiate a light adjustable lens, for example, inside a human eye, with an appropriate amount of radiation in an appropriate pattern by measuring aberrations in the system containing the lens; aligning a source of the modifying radiation so as to impinge the radiation onto the lens in a pattern that corresponds to the aberration; and controlling the quantity of the impinging radiation whereby to decrease the aberration. The quantity of the impinging radiation is controlled by controlling the intensity and duration of the irradiation. The pattern is controlled and monitored while the lens is irradiated. | ||||||
| 260 | Initiator and ultraviolet absorber blends for changing lens power by ultraviolet light | US11149837 | 2005-06-10 | US20060142528A1 | 2006-06-29 | Jagdish Jethmalani; Shiao Chang; Robert Grubbs |
| Novel blends of photo-initiators and photo-absorbers are disclosed. By the proper selection of the type and amount of absorber and initiator used in a composition, it is possible to regulate the conditions under which photo-induced reactions occur. In a specific embodiment, blends of UV initiators and photoabsorbers are used to control the conditions under which UV initiated polymerization occurs. | ||||||
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