最新美国发明专利
Document Document Title
US11459598B2 Multiplex DNA immuno-sandwich assay (MDISA)
This invention is directed to a method for detecting near and distant interactions between cells, organelles and other large structures. This method can also be used for specific detection and quantification of Antibody or other binding moiety protein-protein and macro-molecular interactions, as well as quantitative analysis of multiple proteins and their modifications.
US11459592B2 Processes for the production of cannabinoids from a carbon source precursor
A method is provided for biosynthetic production of cannabinoids in microorganisms from a carbon source precursor. This method describes the genetic modifications needed to engineer microorganisms to produce cannabinoids as well as a method for identifying and quantifying cannabinoids from fermentation broth. A system is also provided for tuning the method to produce different cannabinoids of interest by systematically modulating the enzymes encoded by the genetic modifications introduced in the microorganism.
US11459589B2 Microbial fermentation for the production of terpenes
The invention provides a method for producing a terpene or a precursor thereof by microbial fermentation. Typically, the method involves culturing a recombinant bacterium in the presence of a gaseous substrate whereby the bacterium produces a terpene or a precursor thereof, such as mevalonic acid, isopentenyl pyrophosphate, dimethylallyl pyrophosphate, isoprene, geranyl pyrophosphate, farnesyl pyrophosphate, and/or farnesene. The bacterium may comprise one or more exogenous enzymes, such as enzymes in mevalonate, DXS, or terpene biosynthesis pathways.
US11459584B2 Gene sequence of recombinant human type II mitochondrial dynein-like GTPase and uses thereof
A gene sequence of recombinant human type II mitochondrial dynein-like GTPase having a nucleotide sequence shown in SEQ ID NO: 1 and uses thereof. A fusion nucleic acid comprising a nucleic acid encoding human type II mitochondrial dynein-like GTPase. A recombinant expression vector comprising the nucleic acid or a fusion nucleic acid. A transformant by which the nucleic acid or the fusion nucleic acid is introduced into a host. A non-human mammalian ADOA model based on the inactivation of the gene of type II mitochondrial dynein-like GTPase, which can effectively improve the pathological manifestations of ADOA using a recombinant expression vector encoding the human type II mitochondrial dynein-like GTPase. The expression level of the nucleic acid encoding the human type II mitochondrial dynein-like GTPase is higher, therefore, more human type II mitochondrial dynein-like GTPase can be obtained in the mitochondria. which can better treat eye diseases such as ADOA.
US11459581B2 Nucleotide sequences and corresponding polypeptides conferring modulated growth rate and biomass in plants grown in saline and oxidative conditions
The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of improved plant size, vegetative growth, growth rate, seedling vigor and/or biomass in plants challenged with saline and/or oxidative stress conditions. The present invention further relates to the use of these nucleic acid molecules and polypeptides in making transgenic plants, plant cells, plant materials or seeds of a plant having plant size, vegetative growth, growth rate, seedling vigor and/or biomass that are improved in saline and/or oxidative stress conditions with respect to wild-type plants grown under similar conditions.
US11459579B2 Transgenic plants produced with a K-domain, and methods and expression cassettes related thereto
Methods and compositions of improving plant yield by introducing into a plant the K-domain of a MADS box gene are disclosed. The expression of the K-domain provides plants with altered flower development, plant size and leaf development.
US11459571B2 Protein extraction method without lysing cells
A method for extracting protein without lysing cells includes: step 1: combining a penetrating peptide CPP gene having a sequence as set forth in SEQ ID NO: 1 and a bacterial lyase T4L gene having a sequence as set forth in SEQ ID NO: 2 through a flexible connecting peptide GGGGS gene having a sequence as set forth in SEQ ID NO: 3 to form a fusion enzyme CPP-T4L gene having a sequence as set forth in SEQ ID NO: 4; step 2: inserting the fusion enzyme CPP-T4L gene, and obtaining a recombinant host strain; step 3: cloning a target protein expression gene, and then constructing a recombinant expression strain; step 4: first inducing the expression of the target protein expression gene; starting the expression of the fusion enzyme CPP-T4L gene, and releasing a target protein; step 5: collecting cell lysis supernatant to recover the target protein.
US11459569B2 Nanometric pharmaceutical composition in the form of liposomes or nanoemulsion containing specific sequences of interference RNA
The present invention is inserted in the fields of nanotechnology, pharmacy and genetics and refers to specific sequences of interference RNA (siRNA), capable of silencing the gene responsible for the expression of an adhesion protein, which produces overexpressed extracellular adenosine in tumors, the enzyme ecto-5′-nucleotidase/CD73 (CD73). The specific siRNA sequences for CD73 are proposed in a nanometer scale composition in the form of liposomes or nanoemulsions in order to promote a site-directed release complex capable of being incorporated into several types of formulation, such as intratumor, intravenous injection or administration nasal. The siRNA sequences to silence CD73 can also be applied in the manufacture of kits and/or in silencing tests of CD73 for scientific research using liposomes, nanoemulsions or other transfection reagents.
US11459566B1 Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA
This invention relates to compounds, compositions, and methods useful for reducing α-1 antitrypsin target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
US11459565B2 Hippo and dystrophin complex signaling in cardiomyocyte renewal
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
US11459564B2 Modulation of frataxin expression
Certain embodiments are directed to methods and compounds for increasing FXN. Such methods and compounds are useful for increasing expression of FXN in cells and animals.
US11459560B2 Methods and compositions for reprogramming cells
The present disclosure relates to methods and compositions for reprogramming cells to a pluripotent state. In particular, it relates to an integration- and feeder cell-free method for reprogramming primary human fibroblast cells to induced pluripotent stem cells (iPSCs).
US11459556B2 Methods of preparing a solid composition containing proteases
Described are compositions, in particular lyophilizates, containing proteolytic enzymes, and methods for producing the compositions. Typically these compositions contain one or more proteases with collagenase activity and a neutral protease, for example, thermolysin. The compositions are free of acetate salts. Surprisingly, such compositions can be dissolved in water more rapidly than lyophilized protease mixtures of the state of the art.
US11459554B2 Enzyme complex comprising beta-agarase, kappa-carrageenase and anhydro-galactosidase, and use thereof
The present invention relates to an enzyme complex which the following (i) to (iv) are combined: (i) chimeric beta-agarase formed by a fusion of beta-agarase and the dockerin module of endo-β-1,4-glucanase-B; (ii) chimeric kappa-carrageenase formed by a fusion of kappa-carrageenase and the dockerin module of endo-β-1,4-glucanase-B; (iii) chimeric anhydro-galactosidase formed by a fusion of anhydro-galactosidase and the dockerin module of endoβ-1,4-glucanase-B; and (iv) mini cellulose-binding protein A, and to a method of degrading red algal biomass using the same. According to the present invention, an enzymatic degradation process is applied for the production of agar degradation products, deviating from conventional methods that relied on physical and chemical pretreatment processes. Thus, the present invention will greatly contribute to efficiently converting marine algae into valuable products by use of a convenient, cost-effective, highly efficient and environmentally friendly degradation system while controlling the products.
US11459546B2 Method for producing somatic cell, somatic cell, and composition
The present invention addresses the problem of providing: a method for producing brown adipocytes, osteoblasts, cartilage cells, neural cells, or cardiac cells from somatic cells without performing artificial gene transfer; brown adipocytes, osteoblasts, cartilage cells, neural cells, or cardiac cells; or a composition including a combination of chemical substances that can be used for the aforementioned production method. An example of the present invention is a method for producing brown adipocytes, osteoblasts, cartilage cells, neural cells, or cardiac cells including a step for culturing somatic cells in the presence or absence of an inhibitor or activator selected from the group consisting of an ALK5 inhibitor, an ALK6 inhibitor, an AMPK inhibitor, a cAMP activator, an ALK2 inhibitor, an ALK3 inhibitor, a GSK3 inhibitor, and an Erk inhibitor.
US11459544B2 Gene-regulating compositions and methods for improved immunotherapy
The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.
US11459542B2 Micro-physiological organoid culture
The present invention is in the field of the cultivation of biological cells and tissues with organ-like function on a microphysiological scale and provides a method for the microphysiological co-cultivation of 3D organoid tissue and at least one 2D cell layer.
US11459536B1 Closed cell culturing and harvesting system
A bioreactor includes a base and a lid. The base includes two opposing curved or convoluted surfaces, two opposing flat surfaces, a window disposed on one of the flat surfaces, the window having a higher degree of transparency compared to other portions of the base, wherein images or videos of cells are captured through the window by non-invasive ISM device, and a rounded bottom. The lid is attachable to the base. The lid includes a shaft and a semipermeable membrane attached to the shaft, the semipermeable membrane being permeable to oxygen but impermeable to viruses and bacteria. The PAT-based online analysis directs the adaptive manipulations of bioreactor towards efficient, automated, and GMP-compliant clinical protocols of cell culture.
US11459534B2 Organ container
An organ container includes flexible films and a tube holder. The films hold an organ in contact with the surface of the organ. The tube holder holds tubes that extend between the organ in the films and an outside of the films. This makes it possible to hold and preserve the organ while allowing a liquid to be perfused through the organ via the tubes. It is also possible to reduce movements of the organ relative to the organ container and to reduce damage to the organ.
US11459530B2 Solution for removing various types of deposits from a surface
The invention relates to the field of removing various types of deposits from a surface, specifically to means for cleaning metallic and ceramic surfaces of industrial equipment, and can be used for removing deposits, such as oxides of metals (iron, chromium, nickel, etc.), carbonate and salt deposits, asphaltene-resin-paraffin deposits and deposits of a petroleum nature, and deposits of an organic and biological deposits. The proposed solution for removing various types of deposits contains hydrogen peroxide, complexone, an anti-foaming agent, water-soluble calixarene and water in the following ratio: hydrogen peroxide, a catalyst for decomposing peroxide compounds, an antifoaming agent, complexone, water-soluble calixarene and water in the following quantitative ratio:2-35% by mass of hydrogen peroxide; 2-20% by mass of a catalyst for decomposing peroxide compounds; 3-10% by mass of complexone; 0.1-5% by mass of surface-active agent; 0.01%-1.0% by mass of anti-foaming agent; 0.01-1% by mass of water-soluble calixarene, with the remainder being water. The technical result is an increase in the effectiveness of action of a solution (degree of cleaning) for cleaning surfaces soiled with deposits having a high content of organic substances, while simultaneously extending the field of use of said solution.
US11459527B2 Cleansing compositions and use thereof
A cleansing composition comprising an aqueous solution of an anionic polymer, a nonionic polymer and a system of surfactants. Solutions as described herein comprise two distinct aqueous phases having different compositions and density. Further methods of use are also disclosed.
US11459524B2 Fragrance composition
The present disclosure provides a fragrance accord comprising a mixture of dihydromyrcene and at least one compound selected from peppermint cyclohexanone, menthol, isopulegol, pulegol, menthyl acetate, and optionally at least one compound selected from citroxide, elemicin, elemol, geranic oxide, vanillyl ethyl ether, vanillyl butyl ether, caryophyllene beta, and zingiberene alpha. Consumer products containing said fragrance accord are also provided herein.
US11459523B2 Method for the pretreatment of a biofuel feedstock
In an aspect, a method is disclosed that includes contacting a composition with an aqueous solution to yield a mixture, where the composition includes one or more of animal fats, animal oils, plant fats, plant oils, vegetable fats, vegetable oils, greases, and used cooking oil, about 5 wt. % or more of free fatty acids, about 10 wppm or more of total metals, about 8 wppm or more phosphorus, about 20 wppm or more of nitrogen, and the aqueous solution includes ((NH4)2H2EDTA, (NH4)4EDTA, a monoammonium salt of diethylenetriaminepentaacetic acid, a diammonium salt of diethylenetriaminepentaacetic acid, a triammonium salt of diethylenetriaminepentaacetic acid, a tetraammonium salt of diethylenetriaminepentaacetic acid, (NH4)5DTPA, a combination of citric acid and Na4EDTA, a combination of citric acid and Na2H2EDTA, a combination of citric acid and a monosodium salt of diethylenetriaminepentaacetic acid, a combination of citric acid and a disodium salt of diethylenetriaminepentaacetic acid, a combination of citric acid and a trisodium salt of diethylenetriaminepentaacetic acid, a combination of citric acid and a tetrasodium salt of diethylenetriaminepentaacetic acid, a combination of citric acid and Na5DTPA, or a combination of any two or more thereof, where the method further includes centrifuging the mixture to yield a first treated composition, wherein the first treated composition has less total metals and less phosphorus than the composition.
US11459521B2 Lubricant composition and dispersants therefor having a beneficial effect on oxidation stability
A lubricant composition having greater than 50 percent by weight of a base oil, a dispersant composition comprising: i) a first dispersant comprising one or more reaction products of at least one polyisobutenyl succinic acid or anhydride having a polyisobutenyl group with a number average molecular weight that is less than or equal to 1300, and at least one polyamine; and ii) a second dispersant comprising one or more reaction products of at least one polyisobutenyl succinic acid or anhydride having a polyisobutenyl group with a number average molecular weight greater than 1300, and at least one polyamine; and at least one ashless antioxidant; and wherein a weight ratio of the second dispersant to the dispersant composition is 0.66:1 to 1:1 or a ratio of the weight percentages of nitrogen contributed by the second dispersant to nitrogen of the dispersant composition is 0.62:1 to 1:1.
US11459520B2 Aliphatic tetrahedral borate compounds for lubricating compositions
An additive for a lubricating composition includes an ionic tetrahedral borate compound which includes a cation and a tetrahedral borate anion having a boron atom, the boron atom has at least one aliphatic bidentate di-oxo ligand. The cation may be selected to provide detergent and/or dispersant and/or antioxidant properties to a lubricating composition.
US11459516B2 Two stage hydrodearylation systems to convert heavy aromatics into gasoline blending components and chemical grade aromatics
Systems and methods include an aromatics complex (ARC), the ARC in fluid communication with a naphtha reforming unit (NREF) and operable to receive a reformate stream produced by the NREF, and the ARC further operable to separate the reformate stream into a gasoline pool stream, an aromatics stream, and an aromatic bottoms stream; and a hydrodearylation unit operable to receive heavy, non-condensed, alkyl-bridged, multi-aromatic compounds from the aromatic bottoms stream, the hydrodearylation unit further operable to hydrogenate and hydrocrack the heavy, non-condensed, alkyl-bridged, multi-aromatic compounds to produce a stream suitable for recycle to the NREF or the reformate stream, where the hydrodearylation unit is further operable to receive hydrogen produced in the NREF.
US11459515B2 Process for upgrading hydrocarbon feedstock utilizing low pressure hydroprocessing and catalyst rejuvenation/regeneration steps
Heavy hydrocarbon feedstocks including crude oil are upgraded under relatively low pressure conditions in an ebullated-bed hydroprocessing zone to remove the heteroatom containing hydrocarbons. Catalyst particles are regenerated/rejuvenated and recycled back to the ebullated-bed hydroprocessing reaction zone. The regeneration/rejuvenation is effective to restore catalytic activity while minimizing leaching of the active components(s).
US11459509B2 Catalytic hot-gas filtration of biomass pyrolysis vapors
The present disclosure relates to a device that includes a filter element and a catalyst, where the filter element is configured to remove particulate from a stream that includes at least one of a gas and/or a vapor to form a filtered stream of the gas and/or the vapor, the catalyst is configured to receive the filtered stream and react a compound in the filtered stream to form an upgraded stream of the gas and/or the vapor, further including an upgraded compound, and both the filter element and the catalyst are configured to be substantially stable at temperatures up to about 500° C.
US11459505B1 Environmentally safe concrete or mortar etching composition and methods thereof
Disclosed herein is an environmentally safe etching composition and method for a concrete or mortar surface. The composition includes, in some embodiments, an aqueous solution of urea, acetic acid, a buffering agent, an anticorrosive agent, and a surfactant with no more than about 30% (w/v) urea and at least about 10% (v/v) acetic acid. The method includes, in some embodiments, obtaining the etching composition; applying the etching composition to the concrete or mortar surface at a prescribed ratio of the etching composition to the concrete or mortar surface; allowing the etching composition to stand on the concrete or mortar surface for a prescribed amount of time; and washing the concrete or mortar surface with water to produce an etched surface of the concrete or mortar.
US11459502B2 Method for making nano- and micro-particles for use as a proppant and fluid-loss-control additive
Nano- and micro-particles (NMP) can be formed from an oil/water emulsion. The emulsion is made by mixing a liquid solvent, at least one surfactant, a particle-forming compound, and at least curing agent. If desired, pH control agents and viscosity enhancers can be added to the liquid solvent. The particle-forming compound and the curing agents are mixed together and form the oil phase in the emulsion and after curing, the particles are formed. The nano- and micro-particles can be used as proppant to enhance the conductivity of nano- and microfractures and fluid-loss-control additive for hydraulic fracturing operations.
US11459500B2 Foamed treatment fluids comprising nanoparticles
Foamed treatment fluids for use in subterranean formations are provided. In one embodiment, a method of using a foamed treatment fluid comprises: introducing a foamed treatment fluid into a wellbore penetrating at least a portion of a subterranean formation at or above a pressure sufficient to create or enhance one or more fractures in the subterranean formation, wherein the foamed treatment fluid comprises an aqueous base fluid, one or more surfactants, a natural gas, and a plurality of nanoparticles.
US11459498B2 Alkyl lactone-derived corrosion inhibitors
Disclosed are alkyl lactone-derived hydroxyamide and alkyl lactone-derived hydroxyester used in compositions and methods for inhibiting corrosion. The alkyl lactone-derived hydroxyamide and alkyl lactone-derived hydroxyester are reaction products of an alkyl lactone and an amine, and an alkyl lactone and an alcohol, respectively.
US11459494B2 Silicone composition for release paper or release film, and release paper and release film
A compound that is devoid of epoxy groups and has a quantity of alkenyl groups corresponding to 5-1000 times the alkenyl content of a base polymer, and/or an organopolysiloxane that is devoid of alkenyl groups, has an average degree of polymerization of 2-50, and contains, per molecule, 30 mol % or more of siloxane units having epoxycyclohexyl groups bonded to silicon atoms via carbon atoms, are/is blended with a silicone composition for a release film as adhesion-enhancing components.
US11459493B2 Curable acetoacetylated resin compositions and additives comprising adhesion promoters, green strength enhancers, or combinations thereof
This invention relates to a curable composition comprising: I. Component (I) comprising at least one resin having at least one functional group selected from the group consisting of β-ketoester and malonate functional groups, II. Component (II) comprising at least one curing agent having at least one aldehyde functional group, and III. Component (III) comprising at least one compound having amine functionality, salts thereof, or combinations thereof; IV. Component (IV) which is at least one additive comprising at least one adhesion promoter, at least one green strength enhancer, or combinations thereof, or wherein said at least one additive is both an adhesion promoter and a green strength enhancer.
US11459492B2 Adhesive composition having anti-fogging property
The present invention aims to provide an adhesive composition having excellent adhesive property and excellent anti-fogging property by way of simple and easy means such as co-extrusion with a substrate film, extrusion coating, solvent coating, etc. According to the present invention, there is provided an adhesive composition, characterized in that it contains a polyester resin (A) and an anti-fogging agent (C), and satisfies the following requirement (1): (1) Glass transition temperature of the polyester resin (A) is from −30 to 30° C.
US11459491B2 Structural adhesive composition having high elongation and impact resistance
A structural adhesive composition having high elongation and impact resistance contains an epoxy resin, a urethane resin formed by using a polyol comprising a long chain as a functional group, and an epoxy curing agent.
US11459486B2 Polishing composition containing amphoteric surfactant
There are provided a polishing composition that gives, in the step of polishing a wafer, a flat polished surface having a reduced height difference between a central region and a peripheral region (laser mark region) of the wafer, and a method for producing a wafer using the polished composition. A polishing composition comprising water, silica particles, an alkaline substance, and an amphoteric surfactant of formula (1): wherein R1 is a C10-20 alkyl group, or a C1-5 alkyl group containing an amide group; R2 and R3 are each independently a C1-9 alkyl group; and X−is a C1-5 anionic organic group containing a carboxylate ion or a sulfonate ion. Silica particles in the form of an aqueous dispersion of silica particles having a mean primary particle diameter of 5 to 100 nm may be used. A method for producing a wafer, wherein in the step of polishing a wafer, polishing is performed until a height difference between a central region and a peripheral region of the wafer becomes 100 nm or less.
US11459485B2 Non-fluorinated coating and finish agents
The present invention relates to a coating composition with 10 to 100% by weight of a non-fluorinated compound mixture, which comprises at least one compound b and at least one compound a, c, or d: a) alkali metal salt of poly(meth)acrylic acid, alkali metal salt of poly(meth)acrylic acid copolymer, ammonium compound or amine salt of poly(meth)acrylic acid, ammonium compound or amine salt of poly(meth)acrylic acid copolymer, or mixtures thereof; b) silicone polyether, alkali metal salt of silicone polyether carboxylate, ammonium compound or amine salt of silicone polyether carboxylate, or mixtures thereof; c) salt of hydrolyzed α-olefin/maleic anhydride copolymer, salt of esterified α-olefin/maleic anhydride copolymer, α-olefin/maleic anhydride copolymer amic acid resin or salt thereof, or mixtures thereof; or d) polycarboxylate calcium sequestrants or mixtures thereof. Such coatings exhibit improved soil and stain cleaning performance.
US11459483B2 Low temperature cure coating formed via polarity-facilitated catalyst migration between layers in a double layer curing mechanism
A double coating, curing method, cured coating, and kit are provided. A first layer of the double coating can be a first cure coating composition, which has a first hydroxy-functional resin, a first crosslinking agent, and a non-polar catalyst. A second layer of a second cure coating composition can have a second hydroxy-functional resin, a second crosslinking agent, and a polar catalyst. The non-polar catalyst catalyzes crosslinking between the second hydroxy-functional resin and crosslinking agent, and not between the first hydroxy-functional resin and crosslinking agent. The polar catalyst catalyzes crosslinking between the first hydroxy-functional resin and crosslinking agent, and not between the second hydroxy-functional resin and crosslinking agent. The polarity of the catalysts can facilitate catalyst migration from one layer to the other. The separate compositions can be shelf-stable and/or the curing can occur at low temperature.
US11459478B2 Coating compositions containing a hydropyphenyl functional polymer and a latex polymer
Coating compositions comprising a hydroxyphenyl functional polymer, a latex polymer, a cross linker, and one or more solvents, and optionally a dispersant, a lubricant and/or one or more pigments are disclosed. In some embodiments the compositions can be used to coat substrates such as cans and other packaging for food and beverages. The coating compositions of the disclosure show favorable flavor scalping properties.
US11459476B2 Production method for pigment aqueous dispersion
The present invention relates to [1] a process for producing a pigment water dispersion liquid of polymer particles containing an azomethine metal complex pigment (A), said process including the step of subjecting a mixture containing the azomethine metal complex pigment (A), an uncrosslinked aromatic group-containing polymer (b) and water to dispersion treatment using a medialess disperser at an accumulated input energy of not more than 5.0 kWh/kg, [2] a pigment water dispersion liquid containing an azomethine metal complex pigment (A) and a polymer dispersant (B), in which in an optical absorption spectrum of the pigment water dispersion liquid, a ratio of a maximum absorbance (A1max) in a wavelength range of not less than 440 nm and less than 465 nm to a maximum absorbance (A2max) in a wavelength range of not less than 420 nm and less than 440 nm [(A1max)/(A2max)] is not less than 1.000, and [3] a water-based ink for ink-jet printing, containing the aforementioned pigment water dispersion liquid.
US11459472B2 Microwavable solvent-based packaging ink composition
Described herein are printing ink compositions suitable for printing of microwavable flexible packaging. The printed black ink exhibits low microwave energy absorption, thus minimizing the risk of charring, arcing, ignition, distortion or burning during microwave heating processes. Nitrocellulose resin, a solvent, a polyurethane resin, and a carbon black pigment having at least one of an imaginary permittivity of ≤3, preferably ≤2, and a surface oxygen content of 1 wt % to 3 wt %, preferably 1.5 wt % to 2.5 wt % are among the components of the printing ink compositions. Also described is packaging suitable for exposure to microwave energy upon which the inks have been printed.
US11459469B2 Effect pigments
Effect pigments based on Al2O3 flakes with high weather resistance and less photoactivity and to their use thereof in paints, industrial coatings, automotive coatings, printing inks, cosmetic formulations. The effect pigments have a ratio of the amount by weight of Al2O3 of the Al2O3 flake and the amount by weight of the metal oxide(s) of the coating layer(s) in the range of from 27:73 to 83:17 based on the total weight of the effect pigment.
US11459468B2 Conductive doped-epoxy hybrid surfacing film
Conductive films comprising epoxy materials doped with graphene, and combined with a metal component to form a hybrid conductive surfacing film for use as lightning strike protection surfacing films for composite structures are disclosed, along with their methods of manufacture.
US11459466B2 Compositions and coatings with non-chrome corrosion inhibitor particles
Compositions are described for protecting a metal surface against corrosion. The composition includes a corrosion-inhibiting particle. The corrosion inhibiting particle may be usable in an epoxy resin-based coating or an olefin resin-based coating. The particle may include a core and a protectant. The core may include a water soluble corrosion inhibitor. The protectant may be disposed on at least a portion of a surface of the core and may be covalently or ionically bonded to a thiol group of the corrosion inhibitor. The protectant may be configured to reduce reaction between the core and the epoxy resin or the olefin resin. Methods of making the compositions are also disclosed.
US11459464B2 Mold coating agent with adjusted acid value having function as concrete releasing agent
The present invention relates to a form coating agent, which has an adjusted acid value and a function of releasing forms from concrete. The present invention uses a copolymer containing: A) melamine polymer resin; B) polystyrene resin; C) phenol-formalin resin; D) polymethylmethacrylate; E) polyacrylate-based resin; and F) polyvinyl chloride.
US11459462B2 Charge-transport material and utilization thereof
A charge transport material containing a charge transport polymer that satisfies at least one of (I) or (II) described below: (I) to independently have both a monovalent substituent having an alicyclic structure of 7 or more carbon atoms, and a monovalent substituent having a carbonyl-containing group; and (II) to have a monovalent substituent that includes a monovalent substituent having an alicyclic structure of 7 or more carbon atoms bonded directly to a carbonyl-containing group.
US11459458B2 Hydrolysis resistant polyamides
A hydrolysis resistant polyamide composition comprising from 50 wt % to 80 wt % polyamide polymer having a theoretical amine end group content of at least 55 μeq/gram; and from 25 wt % to 60 wt % glass fibers. The weight ratio of polyamide polymer to glass fibers ranges from 0.5:1 to 4.0:1. The polyamide composition comprises less than 0.06 wt % copper; and/or from 1 ppb to 0.24 wt % non-copper metal halide compound. The polyamide composition, when hydrolysis aged for 500 hours at 130° C., demonstrates an impact resilience greater than 40 kJ/m2, as measured at 23° C.
US11459456B2 Thermoplastic resin composition for plating
A thermoplastic resin composition for plating of the present invention comprises: about 35 wt % to about 60 wt % of a polycarbonate resin; about 1 wt % to about 20 wt % of a first rubber modified vinyl graft copolymer; about 5 wt % to about 30 wt % of a second rubber modified vinyl graft copolymer; and about 25 wt % to about 50 wt % of an aromatic vinyl copolymer resin, wherein the first rubber modified aromatic vinyl graft copolymer and the second rubber modified aromatic vinyl graft copolymer are present in a weight ratio of about 1:1 to about 1:10. The thermoplastic resin composition for plating and a plated molded product comprising the same have good etching property, plating adhesion, impact resistance, heat resistance and the like.
US11459455B2 Method for producing polyhydroxyalkanoic acid
An object of the present invention is to provide a method for producing PHA capable of providing PHA (for example, a PHA powder) having excellent thermal stability with high productivity. The present invention is a method for producing polyhydroxyalkanoic acid, the method including a step (a) and a step (b) below: step (a) of preparing an aqueous suspension liquid containing polyhydroxyalkanoic acid and polyvinyl alcohol and having a pH of 7 or less; and step (b) of spray-drying the aqueous suspension liquid prepared in the step (a).
US11459453B2 Broad molecular weight distribution polypropylenes with high melt flow rates and high flexural modulus
Provided is a reactor grade polypropylene suitable for injection molding applications comprising within a range from 0 wt % to 4 wt % ethylene and/or C4 to C12 α-olefin derived units, the polypropylene produced from a single catalyst and single stage polymerization process, and having a melt flow rate (MFR, 230° C./2.16 kg) greater than 10 g/10 min, and a 1% secant flexural modulus of at least 250 kpsi (1720 MPa).
US11459446B2 Flame retardant containing aromatic phosphoric acid ester, and thermoplastic resin composition containing same
A flame retardant containing an aromatic phosphoric acid ester represented by the general formula (I): wherein R1 to R4, R7, and R8 each independently represent a C1-4 alkyl group or a C1-4 alkoxy group; R5, R6, and R9 each independently represent a C1-10 alkyl group or a C1-10 alkoxy group; n represents an integer of 1 to 10; n1 and n2 each independently represent an integer of 0 to 3; m1 and m2 each independently represent an integer of 0 to 4; p represents an integer of 0 to 26; and k represents an integer of 1 to 12; and when p is 2 or more, any two substituents R9 may be bonded to each other, and may be bonded to a carbon atom(s) of a ring to which the above substituents R9 are bonded, forming another ring.
US11459442B2 Ethylene acrylate rubber composition and molded article thereof
The present disclosure provides an ethylene acrylate rubber composition which has all of oil resistance, heat resistance and hydrolysis resistance with good balance after molding and cross-linking, and a molded article formed of a cross-linked substance of the ethylene acrylate rubber composition. The ethylene acrylate rubber composition contains 100 parts by mass of an ethylene acrylate rubber, 10 to 50 parts by mass of a plasticizer with an SP value of 7 or more and 0.05 to 30 parts by mass of a cross-linking agent selected from polyvalent aliphatic primary amine or derivatives thereof. The content of a plasticizer with an SP value of less than 7 in the ethylene acrylate rubber is less than 0.1 parts by mass. Further, a molded article formed of a cross-linked product of the ethylene acrylate rubber composition is provided.
US11459438B2 Hollow polymer particles for thermal insulation
A thermal insulating additive, product formed therefrom, and method of making the same, wherein the thermal insulating additive comprises a plurality of hollow polymeric particles having an average particle size up to about 0.3 micrometers. The hollow polymeric particles exhibit a mechanical strength in a compression test up to about 420 psi and a thermal conductivity that is less than 0.150 W/m-k. The hollow polymeric particles are individually formed as an alkaline swellable core that is at least partially encapsulated with two or more shell layers; the alkaline swellable core prior to swelling exhibits an average particle size that is less than about 50 nanometers.
US11459430B2 Method for preparing superabsorbent polymer, and superabsorbent polymer
The present invention relates to a method for preparing superabsorbent polymer that introduces a plate type and rod-shaped clay additive in the superabsorbent polymer, and thus exhibits basic properties of a superabsorbent polymer equivalent to or much better than the existing superabsorbent polymer through multi-crosslinking, and particularly, can improve absorbency under pressure (AUP), and a superabsorbent polymer obtained thereby.
US11459429B2 Perfluoroelastomer composition
The invention pertains to a perfluoroelastomer composition comprising: at least one perfluoroelastomer comprising iodine and/or bromine atoms [perfluoroelastomer (A)]; from 0.5 to 5 weight parts, per 100 parts by weight of said perfluoroelastomer (A), of at least one bis-olefin [bis-olefin (OF)] having general formula (1) wherein R1, R2, R3, R4, R5 and R6, equal or different from each other, are H, a halogen, or a C1-C5 optionally halogenated group, possibly comprising one or more oxygen group; Z is a linear or branched C1-C18 optionally halogenated alkylene or cycloalkylene radical, optionally containing oxygen atoms, or a (per)fluoropolyoxyalkylene radical; from 0.1 to 3 weight parts, per 100 parts by weight of said perfluoroelastomer (A), of at least one organic peroxide; from 0.1 to 3 weight parts, per 100 parts by weight of said perfluoroelastomer (A), of at least one organic base [base (B)] selected from the group consisting of: (i) non-aromatic primary amines or amides complying with general formula (B1m) or (Bid): Rbm—[C(0)]t—NH2 (B1m) H2N—[C(O)]t′—Rdm—[C(O)]t″—NH2 (Bid) wherein: each of t, t′ and t″, equal to or different from each other and at each occurrence is zero or 1; Rbm is a monovalent hydrocarbon non-aromatic group having 12 to 30 carbon atoms; Rdm is a divalent hydrocarbon non-aromatic group having 6 to 30 carbon atoms; and (ii) cycloaliphatic secondary or tertiary amines complying with general formula (II) (B2m) or (B2d) wherein: Cy represents a divalent aliphatic group comprising at least 4 carbon atoms, optionally comprising one or more than one ethylenically unsaturated double bond, and optionally comprising one or more catenary nitrogen atoms, forming a cycle with the nitrogen atom which is connected thereto; Cy′ represent a trivalent aliphatic group comprising at least 5 carbon atoms, optionally comprising one or more than one ethylenically unsaturated double bond, and optionally comprising one or more catenary nitrogen atoms, forming a cycle with the nitrogen atom which is connected thereto.
US11459427B1 Synthesis of polyaniline or derivatives thereof
Provided are synthesis methods of polymerizing aniline or derivatives thereof. The production of polyaniline or polyaniline derivatives is controlled by the type of oxidant added in the reaction medium. The methods include the step of using a safe and environmentally friendly carbomethyl cellulose (CMC) or modified CMC as an oxidant in the polymerization reaction to produce polyaniline or aniline derivatives. Synthesis methods of producing O-CMC and O-CMC-S oxidants are also provided herein.
US11459420B2 Block copolymers, membranes and methods
Block copolymers, thin films including block copolymers, and methods for forming block copolymers and thin films. The block copolymers, due to self-assembly or otherwise, may include one or more regions. The one or more regions may permit a thin film including a block copolymer to be used as a nanostructured membrane.
US11459414B2 Film forming composition containing fluorine-containing surfactant
Methods for forming a film with reduced formation of an edge reservoir at a periphery of a film in which the edge reservoir causes an unnecessary residue that cannot be removed by an etching process. A film forming composition for use in a lithography process includes a surfactant containing a polymer and an oligomer having a C3-5 perfluoroalkyl partial structure. The perfluoroalkyl partial structure may further include an alkyl partial structure. The surfactant is contained in an amount of 0.0001% by mass to 1.5% by mass based on the total solid content of the film forming composition. The film forming composition further includes a coating film resin, the coating film resin is a novolac resin, a condensation epoxy resin, a (meth)acrylic resin, a polyether-based resin, or a silicon-containing resin, etc. The formed film can be used as a resist underlayer film or a resist overlayer film.
US11459413B2 Process control for long chain branching control in polyethylene production
Polymerization process control methods for making polyethylene are provided. The process control methods include performing a polymerization reaction in a polymerization reactor to produce the polyethylene, where ethylene, and optionally one or more comonomers, in the polymerization reaction is catalyzed by an electron donor-free Ziegler-Natta catalyst and an alkyl aluminum co-catalyst. A melt flow ratio (I21/I2) of the polyethylene removed from the polymerization reactor is measured and an amount of long chain branching (LCB) of the polyethylene from the polymerization reactor is controlled by adjusting a weight concentration of the alkyl aluminum co-catalyst present in the polymerization reactor. In addition, an electron donor-free Ziegler-Natta catalyst productivity of the polyethylene being produced in the polymerization reactor is measured from which the amount of LCB of the polyethylene from the polymerization reactor is determined using the measured electron donor-free Ziegler-Natta catalyst productivity and a predetermined relationship between the electron donor-free Ziegler-Natta catalyst productivity and the LCB.
US11459407B2 Chemically modified cellulose fiber and method for producing the same
A sulfated cellulose fiber having a cellulose I crystal structure is provided.A chemically modified cellulose fiber which has a cellulose I crystal and in which some hydroxyl groups of cellulose are substituted with a substituent represented by formula (1). An amount of the substituent introduced is 0.1 mmol to 3.0 mmol per 1 g of the chemically modified cellulose fiber, and an average degree of polymerization is 350 or more. (In formula (1), M represents a monovalent to trivalent cation.) In the production of the chemically modified cellulose fiber, a cellulose fiber is treated with sulfamic acid while maintaining a cellulose fiber shape to allow sulfamic acid and a cellulose fine fiber which is a constituent of the cellulose fiber to react with each other.
US11459392B2 Anti-CD70 antibody drug conjugates
This invention relates to anti-CD70 antibodies and antibody drug conjugates comprising at least one non-naturally-encoded amino acid. Disclosed herein are αCD70 antibodies with one or more non-naturally encoded amino acids and further disclosed are antibody drug conjugates wherein the αCD70 antibodies of the invention are conjugated to one or more toxins. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, including therapeutic, diagnostic, and other biotechnology uses.
US11459391B2 Combination therapies and patient stratification with bispecific anti-EGFR/c-Met antibodies
The present invention relates to combination therapies and patient stratification with bispecific anti-EGFR/c-Met antibodies.
US11459379B2 Immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis
The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.
US11459378B2 Passive antibody dependent cell-mediated activation
In certain embodiments, described herein is a method of treating a subject infected with a pathogen encoding an Fc-binding protein comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. Also described herein is a method for treating cancer in a subject undergoing oncolytic viral therapy comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. Further described herein is a method of activating natural killer (NK) cells in a subject infected with a pathogen, comprising administering to the subject a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody.
US11459377B2 Synthetic library of specific binding molecules
The present invention provides methods for the production of a library of antigen specific antigen binding molecules having a peptide domain structure represented by the following formula (I): FW 1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 comprising (1) isolating RNA from a member of a species in the Elasmobranchii subclass; (2) amplifying DNA sequences from RNA obtained; (3) selecting a DNA sequence from the database prepared; (4) amplifying DNA sequences encoding two or more contiguous peptide domains of FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4; (5) ligating together said amplified DNA sequences to form DNA sequences encoding an antigen specific binding molecule; (6) cloning the amplified DNA obtained into a display vector; and (7) transforming a host with said display vector to produce a library of said antigen specific antigen binding molecules. The invention also provides methods for the production of an antigen specific antigen binding molecule as defined, pharmaceutical compositions comprising such molecules and uses thereof in medicine.
US11459376B2 Compositions and methods for the delivery of therapeutic biologics for treatment of disease
The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier.
US11459375B2 Cyclic peptides for the treatment of Graves' disease
The present invention relates to a cyclic peptide, its use in the treatment, amelioration or prevention of a disease caused by antibodies targeting the thyrotropin-TSH receptor (TSHR) in the thyroid gland, in particular Graves' disease and orbitopathy, and to pharmaceutical compositions comprising the same.
US11459368B2 Insulin-transferrin fusion protein and its prodrug, proinsulin-transferrin, for overcoming insulin resistance
A method of treating Type 2 diabetes (T2D) is provided. The method includes administering to a subject in need thereof an effective amount of a pharmaceutical composition that includes an insulin-transferrin fusion protein or its prodrug, proinsulin-transferrin fusion protein.
US11459366B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11459365B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11459363B2 Materials and methods for treating Friedreich's Ataxia
A Transactivator of Transcription-frataxin (TAT-FXN) fusion polypeptide useful in treating subjects diagnosed with Friedreich's Ataxia, hypertrophic cardiomyopathy, or both are disclosed, as are related methods of treatment and pharmaceutical compositions.
US11459362B2 Recombinant polypepties for membrane fusion and uses thereof
Disclosed is a recombinant polypeptide for facilitating membrane fusion. The recombinant polypeptide having a sequence with at least 80% sequence identity with the ectodomain of p14 fusion-associated small transmembrane (FAST) protein and having a functional myristoylation motif, a transmembrane domain from a FAST protein and a sequence with at least 80% sequence identity with the endodomain of p15 FAST protein. A targeting ligand can be added to the recombinant polypeptide for selective fusion. The recombinant polypeptide can be included in the membrane of a liposome, or the like, to facilitate the delivery of bioactive compounds, such as siRNA, or the recombinant polypeptide can be mixed with a lipid carrier and added to cultured cells to induce cell-cell fusion and heterokaryon formation.
US11459358B2 Substances for targeting various selected organs or tissues
The invention provides conjugates, comprising an organ or tissue targeting moiety linked to a biologically active moiety or linked to a diagnostic moiety. Such a biologically active or diagnostic moiety can be, for example, an oligonucleotide, small interfering RNA, a gene, a virus, a protein, a drug, a small organic molecule, a pharmaceutical, or a detectable agent.
US11459357B2 Polymyxin compounds
The invention provides a polymyxin compound of formula (I) and salts, solvates and protected forms thereof, pharmaceutical compositions comprising the compounds of formula (I), and the use of the compounds and compositions in methods of treatment, such as methods for the treatment of microbial infections. The compounds of formula (I) are represented thus: wherein —R15 is a group: and —R16 is hydrogen; —R17 is hydrogen -L- is a covalent bond or methylene; and —Ar is optionally substituted aryl. The groups —X—, —R1, —R2, —R3, —R4, and —R8 are as defined herein.
US11459355B2 Peptides having octopus octopressin activity and use thereof
The present invention relates to an Octopus minor-specific octopressin peptide comprising the amino acid sequence of SEQ ID NO: 3, and the peptide, by promoting the brooding behaviors of mother Octopus minor to protect her eggs, may increase the hatched larva rate when applied to partial cultivation of octopuses, and thus may be used for the growth of octopus resources.
US11459354B2 Process for purifying liraglutide
The present invention provides improved processes for purifying liraglutide. Liraglutide is purified via two sequential RP-HPLC purifications followed by a salt-exchange step, where a pH is kept constant in the first and second purification steps. In particular, the processes utilize a halogenated solvent in a sample preparation step, which provides better solubility and an environment suitable for decarboxylation for crude liraglutide prior to a RP-HPLC purification.
US11459352B2 Method for polyalkoxylation of nucleic acids that enables recovery and reuse of excess polyalkoxylation reagent
The present invention is related to a method for the preparation of a modified nucleic acid molecule comprising a nucleic acid moiety and a non-nucleic acid moiety by reacting a first reactant and a second reactant, wherein the first reactant comprises the non-nucleic acid moiety and a carboxyl group, and wherein the second reactant is an amino-modified nucleic acid molecule comprising the nucleic acid moiety and an amino modification comprising an amino group which is attached to the nucleic acid moiety, wherein the method comprises the following steps: a) activating the first reactant, preferably the carboxyl group of the first reactant, by a condensation reagent in a water miscible organic solvent, and b) reacting the activated first reactant, preferably the activated carboxyl group of the first reactant, of step a) and the second reactant, preferably the amino group of the amino modification of the amino-modified nucleic acid molecule which has been dissolved in water or a mixture of a water miscible organic solvent and water, whereby the modified nucleic acid molecule is formed.
US11459342B1 Multivariate carboxylate derivatized phenyl-based metal-organic frameworks
A composition having the structure of formula I: [R—Ar—(COOH)2]x[Ar—(COOH)3]2-xM32+  (I) is provided where M is Mn, Cu, Co, Fe, Zn, Cd, Ni, or Pt; R is a bromine, nitro, a primary amine, C1-C4 alkyl secondary amine, C1-C4 alkyl oxy, Br—(C1-C4 alkyl), NO2—(C1-C4 alkyl), a mercaptan, and reaction products of any of the aforementioned with acyl chlorides of the formulas: CH3(CH2)mC(O)Cl, or CH3(CH(C1-C4 alkyl)CH2)mC(O)Cl, or CH3(CH2)m-Ph-(CH2)pC(O)Cl, where Ph is a C6 phenyl or C6 phenyl with one or more hydrogens replaced with F, C1-C4 fluoroalkyl, or C1-C4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>x>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided.
US11459339B2 Biaryl derivative, preparation method thereof and pharmaceutical application thereof
Disclosed are a biaryl derivative having a structure represented by Formula (I) and inhibitory activity against PD-1/PD-L1 interaction, a preparation method thereof, and a pharmaceutical application thereof. The series of compounds of the can be widely applied to the preparation of a medicament for preventing and/or treating cancer or tumors, immune-related diseases and disorders, contagious diseases, infectious diseases or metabolic diseases that are mediated by a PD-1/PD-L1 signaling pathway, and shows promise for the development of a new generation of PD-1/PD-L1 inhibitors.
US11459337B2 Isothiazolo[5,4-D]pyrimidine compound as IRAK4 inhibitor
Disclosed in the present invention are an IRAK4 inhibitor, and an application thereof in preparation of a drug for treating IRAK4-related diseases. Specifically disclosed are a compound represented by formula (III) and a pharmaceutically acceptable salt thereof.
US11459331B2 Chemical compounds
The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the disclosure have activity as prostaglandin EP4 receptor antagonists, and are useful in the treatment or alleviation of pain and inflammation and other inflammation-associated disorders, such as arthritis, treating or preventing disorders or medical conditions selected from pain, inflammatory diseases and the like. Also described herein are methods of treating pain by administering the compounds of the disclosure, which are EP4 receptor antagonists.
US11459330B2 Substituted bicyclic heterocyclic compounds as PRMT5 inhibitors
The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
US11459326B2 N-pyridinyl acetamide derivatives as Wnt signalling pathway inhibitors
Disclosed are compounds useful as inhibitors of the Wnt signalling pathway. Specifically, inhibitors of Porcupine (Porcn) are contemplated by the invention. In addition, the invention contemplates processes to prepare the compounds and uses of the compounds. The compounds of the invention may therefore be used in treating conditions mediated by the Wnt signalling pathway, for example, in treating cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia; or enhancing the effectiveness of an anti-cancer treatment.
US11459322B2 Indole compounds and their use
The present disclosure relates to indole compounds and pharmaceutical compositions thereof, and their use in stimulating the immune system of patients in need thereof and in treating cancer.
US11459321B2 Broad spectrum antiviral compositions and methods
Novel thiazole- and isoquinoline-containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-spectrum viral infections are also presented. These compounds have shown inhibition of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.
US11459320B2 Deuterated Alpha5 subunit-selective negative allosteric modulators of gamma-aminobutyric acid type A receptors as fast acting treatment for depression and mood disorders
The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders.
US11459309B2 Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making
Described herein are crystalline forms of pharmaceutically acceptable salts of the lysyl oxidase-like 2 (LOXL2) inhibitor (3-(4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yloxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone. Also described are methods of making the LOXL2 inhibitor, pharmaceutical compositions and medicaments comprising the LOXL2 inhibitor, and methods of using the LOXL2 inhibitor in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.
US11459306B2 Compounds, compositions, and methods for treating T-cell acute lymphoblastic leukemia
In an aspect, the disclosure provides for compounds (II), compositions, and methods of administering the compounds and compositions to a patient in need thereof. In another aspect, the disclosure relates to compounds and compositions for treating cancer, for example, lymphoid leukemia. The disclosure further provides for compounds which inhibit two phosphoinositide 3-kinase (PI3K) isoforms, y and δ, pharmaceutical compositions comprising said compounds, and methods of using said compounds and pharmaceutical compositions for treatment, amelioration, and/or prevention of non-Hodgkin lymphoma.
US11459304B2 Ionizable lipidoids and their uses
Provided herein are lipidoid compounds of Formulae (I) and (II), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive lipidoid compounds, compositions, or formulations for treating and/or preventing diseases (e.g., genetic disease, proliferative disease, hematological disease, neurological disease, painful condition, psychiatric disorder, metabolic disorder, long-term medical condition, inflammatory disease, autoinflammatory disease, liver disease, lung disease, spleen disease, familial amyloid neuropathy, cardiovascular disease, viral infection, infectious disease, fibrotic condition, or autoimmune disease) in a subject, methods for synthesizing the compounds described herein, and compounds described herein synthesized by the synthetic methods described herein. The compounds are effective carriers for the delivery of an agent such as a polynucleotide (e.g., RNA) to a cell.
US11459303B2 Process for the synthesis of lofexidine
Disclosed is a process for the synthesis of lofexidine of formula (I) and the hydrochloride salt thereof (II), from ethyl 2-(2,6-dichlorophenoxy)propionate (III) and ethylenediamine in the presence of tetravalent titanium alkoxides, preferably titanium isopropoxide, in an apolar solvent such as toluene. A further object of the present invention is a process for the preparation of the intermediate ethyl 2-(2,6-dichlorophenoxy)propionate (III) from 2,6-dichlorophenol and ethyl 2-chloropropionate in the presence of a polar aprotic solvent and an alkali or alkaline earth carbonate salt, preferably potassium carbonate. Both processes are more cost-effective and more easily industrially scalable than the known procedures, thus enabling the active ingredient to be obtained with high yields at a limited cost.
US11459301B2 Crystalline form of s-apomorphine
The invention is directed to a novel crystalline S-apomorphine hydrochloride hydrate salt.
US11459295B2 2-beta-naphthyl-acetic acid analogs as AKR1C3 inhibitors and methods of using same
The invention includes 2-β-naphthyl-acetic acid derivatives, which are selective AKR1C3 inhibitors. In certain embodiments, the compounds of the invention are (R)-naproxen analogs. The invention further includes methods of treating cancer, such as prostate cancer and/or castration-resistant prostate cancer, using at least one compound of the invention.
US11459292B2 Metal salts and uses thereof
The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
US11459287B1 Arene-immobilized ru(II)TsDPEN complexes: synthesis and applications to the asymetric transfer hydrogenation of ketones
Arene-immobilized Ru(II)TsDPEN Noyori-Ikariya catalysts anchored to silica through the coordinated η6-arene are provided. The catalysts efficiently catalyze many reactions, including the asymmetric transfer hydrogenation of ketones to alcohols.
US11459283B2 Method for producing xylene
A method for producing xylene, including a conversion reaction step of bringing a raw material containing a light hydrocarbon having 2 to 7 carbon atoms as a main component into contact with a crystalline aluminosilicate-containing catalyst to produce a product containing a monocyclic aromatic hydrocarbon having 6 to 8 carbon atoms and a xylene conversion step of subjecting the product to a disproportionation reaction or a transalkylation reaction.
US11459281B2 Method for producing acetylene and syngas
A process for producing acetylene and syngas by partial oxidation of hydrocarbons with oxygen, involving: separately preheating a hydrocarbon and a oxygen-comprising input stream; mixing in a mass flow ratio of the oxygen-comprising to hydrocarbon stream at an oxygen number no more than 0.31; feeding the streams via a burner block to a combustion chamber and therein partially oxidizing the hydrocarbon(s) to a cracking gas; quenching the cracking gas to 80 to 90° C. downstream by injecting an aqueous quench medium to obtain a process water stream-1 and a product gas stream-2; cooling the product gas stream-2 in a cooling column by direct heat exchange with cooling water to obtain a process water stream-2 as bottoms, a product gas stream-2 as uppers, and a sidestream; and depleting the sidestream of soot in an electrofilter to generate therein a process water stream-3 combined with water streams-1/2 to afford the process water stream-4.
US11459277B2 Process for the production of micronized sulfur
The present document describes a method of producing sulfur particles by injecting an unbroken stream of molten sulfur under a pulsation free pressure, from a distance, into tempered water moving at a velocity, to produce a physical reaction of said molten sulfur with said tempered water to produce sulfur particles. Also described are sulfur particles produced by the process and methods of using the same for fertilizing soil.
US11459276B2 Alumina-based heat conductive oxide and method for producing same
The present invention provides an alumina-based thermally conductive oxide that is excellent not only in thermal conductivity but also in chemical resistance, water resistance, and electrical insulation, that has a good kneadability (miscibility) into resins, and that enables to produce a material or an article, such as a resin composition, which is excellent in shapability. The present invention is an alumina-based thermally conductive oxide obtained by firing a starting material mixture containing an aluminum starting material. The aluminum starting material is at least one selected from the group consisting of boehmite, aluminum hydroxide, and alumina, the starting material mixture further contains at least one additional starting material selected from the group consisting of talc, a frit, a boric acid compound, a molybdenum compound, titanium oxide, a magnesium compound, a zinc compound, a zirconium compound, a phosphoric acid compound, and a tungsten compound, and the content of the additional starting material in the starting material mixture is 0.1 to 20 parts by mass based on 100 parts by mass of the aluminum starting material.
US11459269B2 Glazing comprising a stack of thin layers acting on solar radiation and a barrier layer
A transparent substrate, in particular made of glass, provided with a stack of thin layers acting on solar radiation, includes at least one functional layer, this functional layer being combined with at least one barrier underlayer, wherein this barrier underlayer is a layer of silicon dioxide having a thickness of between 15 and 25 nm.
US11459268B2 Tactile elements for deadfronted glass and methods of making the same
Deadfront articles that include a tactile element formed on a first surface of a substrate and a visual element disposed on a second surface of the substrate opposite the first surface. The tactile element is positioned on the first surface of the substrate in a complimentary fashion to the visual element disposed on the second surface of the substrate. The tactile element may include a surface roughness portion having a surface roughness different than the surface roughness of an area bordering the surface roughness portion. The deadfront articles may be incorporated into an automobile interior to provide a visual and haptic display interface for a user.
US11459267B2 Glass plate
A glass sheet contains, as represented by mass percentage based on oxides, SiO2: 65-75%, Al2O3: 0-20%, MgO: 0-5%, CaO: 2-20%, Na2O: 5-20%, K2O: 0-10%, total iron in terms of Fe2O3 (t-Fe2O3): 0.2-1.0%, TiO2: 0.65-1.5%, and CeO2: 0.1-2.0%. A ratio of the content of MgO to RO is 0.20 or less, where RO is a total amount of MgO, CaO, SrO and BaO. Fe-redox is from 30 to 57%. The glass sheet has a visible light transmittance Tv_A of 65% or more, a solar transmittance Te of 50% or less, and a dominant wavelength Dw of transmitted light of from 508 to 580 nm, in terms of a 3.9-mm thickness of the glass sheet. A value of A=([t-Fe2O3]×Fe-redox)/[TiO2] is from 20 to 40, where [t-Fe2O3] is the content of t-Fe2O3 and [TiO2] is the content of TiO2.
US11459263B2 Selective chemical fining of small bubbles in glass
A method of fining glass is disclosed that includes flowing a molten glass bath through a fining chamber. The molten glass bath has an undercurrent that flows beneath a skimmer that is partially submerged in the molten glass bath. One or more fining agents are introduced into the undercurrent of the molten glass bath directly beneath the skimmer from a dissolvable fining material component. In this way, the fining agent(s) may selectively target the gas bubbles drawn under the skimmer within the undercurrent of the molten glass for removal. The method may be employed to fine molten gas produced in a submerged combustion melter. A fining vessel for fining molten glass is also disclosed.
US11459257B1 Method of treating a liquid with nanobubbles
A method of treating a liquid by creating nanobubbles of a desired gas within a target liquid and allowing the desired gas to react with a target component of the target liquid. The desired gas can be selected to be reactive with the target component, and a desired liquid can be formed after the desired gas reacts with the target component.
US11459254B2 Maintaining a steady microbial community in a combined anaerobic-aerobic apparatus
A method and an apparatus for maintaining a stable microbial community in a combined anaerobic-aerobic waste processing system. The system comprises cycling of waste activated sludge between reactors, thereby ensuring a healthy microbial community and an efficient waste decomposition.
US11459245B2 Wastewater and effluent separation and treatment systems
Automated systems and methods for treating wastewater or effluent are provided. In some embodiments, the methods include: using a set of sensors to measure one or more properties of untreated wastewater or effluent; performing at least one potential chemical treatment and at least one potential mechanical treatment on a sample of the untreated wastewater or effluent, wherein the potential chemical and mechanical treatments are selected based on the properties of the untreated wastewater or effluent; using a set of sensors to measure one or more properties of the treated sample; based at least in part on the data regarding the properties of the treated sample, using an information handling system to select at least one chemical treatment and at least one mechanical treatment; and using the information handling system to control one or more components of a chemical treatment subsystem and a mechanical treatment subsystem to perform the selected chemical and mechanical treatments on the untreated wastewater or effluent to produce treated water.
US11459241B2 Method for preparing artificial graphite
A method for preparing artificial graphite includes (A) preparing heavy oil, and forming coke from the heavy oil through continuous coking reaction such that the coke has a plurality of mesophase domains, wherein a size of the mesophase domains ranges between 1 and 30 μm by polarizing microscope analysis; and (B) processing the coke formed by step (A) sequentially by pre-burning carbonization treatment, grinding classification, high-temperature carbonization treatment and graphitization treatment to form polycrystalline artificial graphite from the coke. The method for preparing artificial graphite of the present invention and the polycrystalline artificial graphite prepared thereby are applicable to batteries.
US11459239B2 Graphene, device for producing graphene, and method for producing graphene
A method for producing graphene includes:a pretreatment process of drying and pulverizing a vegetable material to obtain a carbon source;a carbonization process of carbonizing the carbon source to obtain a carbide; anda purification process of removing an impurity containing silica from the carbide obtained in the carbonization process,wherein the carbonization process including a heating process of supplying an inert gas into a chamber and heating the carbon source in the chamber in a plasma atmosphere.
US11459233B2 Process and plant for producing and storing hydrogen
A process for producing and storing hydrogen includes providing an intermediate gas mixture having an increased proportion of hydrogen and contacting of the intermediate gas mixture with a hydrogen carrier medium in order to hydrogenate the hydrogen carrier medium.
US11459230B2 MEMS microphone
A MEMS microphone includes a substrate, a backplate disposed on a side of the substrate, a diaphragm movably disposed between the substrate and the backplate, and a plurality of slots formed on the diaphragm. The slots are spaced apart from each other and have a non-constant width to relieve the residual stress on the diaphragm.
US11459227B2 Hinged microelectromechanical and/or nanoelectromechanical device with out-of-plane movement
Disclosed is a hinged MEMS and/or NEMS device with out-of-plane movement including a first portion and a second portion that is hinged so as to be able to rotate with respect to the first portion about an axis of rotation contained in a first mean plane of the device. The device also includes a hinging element that connects the first portion and the second portion and that is stressed flexurally and a sensing element that extends between the first portion and the second portion and that deforms during the movement of the second portion. Finally, the device includes two blades that extend perpendicularly to the mean plane of the hinge device and parallel to the axis of rotation, the blades being placed between the hinging element and the sensing element and connecting the first portion and the second portion and being stressed torsionally during the movement of the second portion.
US11459226B2 Semiconductor device and semiconductor device manufacturing method
A semiconductor device includes a substrate, a movable portion provided on the substrate, a junction frame provided on the substrate to surround the movable portion, a cap bonded to the junction frame, the cap having a recessed portion and covering a space over the movable portion with the recessed portion facing the movable portion, the cap having an inside wall provided with irregularities, and a prevention film formed on the inside wall of the cap, the prevention film having irregularities on a surface thereof.
US11459225B2 Systems and methods for managing refueling interactions
System, methods, and other embodiments described herein relate to controlling a fuel dispenser. In one embodiment, a method of controlling a fuel dispenser includes broadcasting a pairing signal to a vehicle, receiving, from the vehicle, a confirmation signal confirming completion of a pairing process between the fuel dispenser and the vehicle, transmitting, subsequent to the confirmation signal, a disable signal to the vehicle in response to data from one or more proximity sensors indicating that the vehicle is within a threshold range and a determination that the vehicle is refueling, and transmitting an enable signal to the vehicle in response to a determination that the vehicle is no longer refueling. The disable signal disables a moving capability of the vehicle, and the enable signal restores the moving capability of the vehicle.
US11459224B2 Beverage maker and method of controlling the same
A beverage maker includes: a container; a fermentation tank; a beverage dispenser including a lever configured to control dispensing of the beverage and a limit switch configured to be turned on and off based on manipulation of the lever; a beverage dispensing channel that connects the container and the beverage dispenser and that guides the beverage; a beverage dispensing valve disposed in the beverage dispensing channel; a pressure sensor that measures gas pressure inside the container; and a controller. The controller detects whether the limit switch is turned on, opens the beverage dispensing valve to dispense the beverage accommodated in the container through the beverage dispenser based on detecting that the limit switch is turned on, determines a gas pressure value corresponding to the gas pressure inside the container measured by the pressure sensor, and determines a dispensed amount of beverage based on the gas pressure value.
US11459217B2 Rotary tower crane
A rotary tower crane with a tower, which carries a jib and a counterjib, with a jib stay being guided from a tower top to the jib and to the counterjib. The jib stay tensions only an inner jib portion, the length of which is less than 40% of the total length of the jib, and an outer portion, the length of which is more than 60% of the total length of the jib, forms an untensioned bending beam jib which includes at least one jib piece which tapers in height and which is adjoined on the inner side by at least one jib part of greater height and on the outer side by a jib piece of smaller height.
US11459216B2 Nacelle mountable lift system for a wind turbine
A lift system mountable in a nacelle of a wind turbine has a boom having a proximal end mountable in the nacelle and a distal end extending over a hub of a rotor of the wind turbine when the lift system is mounted in the nacelle. The lift system has a frame structure for mounting the proximal end of the boom in the nacelle, a winch mounted to the boom, a fastener situated below the boom and operatively connected to the winch by at least one cable, and a trolley movably mounted to the boom to permit translation of the trolley longitudinally along the boom thereby permitting longitudinal movement of the fastener with respect to the boom.
US11459215B2 Safety system for a machine
A safety system for a load carrying machine including: a controller, a location sensing arrangement in electronic communication with the processor, the location sensing arrangement configured to determine a location parameter of a load, a monitoring arrangement, the controller configured to receive the location parameter and determine a projected area of the load and control the monitoring arrangement to focus on the projected area to monitor the projected area.
US11459209B2 Light weight load bearing member for elevator system
A lifting member for an elevator system includes a rope formed from plurality of load carrying fibers extending along a length of the lifting member. The plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A coating layer at least partially encapsulates the rope. An elevator system includes a hoistway, an elevator car disposed in the hoistway and movable therein, and a lifting member operably connected to the elevator car to suspend and/or drive the elevator car along the hoistway. The lifting member includes a rope formed from plurality of load carrying fibers extending along a length of the lifting member. The plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A coating layer at least partially encapsulates the rope.
US11459207B2 Safety link with pulley
A safety link for an elevator car traveling in an elevator hoistway includes a hitch bracket slidably mounted to the elevator car frame so as to be movable in the moving directions of the elevator car and biased toward the downward movement direction of the elevator car in normal operating condition, the hitch bracket connected to the governor rope, and a pulley rotatably mounted to the hitch bracket and including an actuation wire wrapped around the pulley and connected to a safety device.
US11459197B2 Document feeder
The document feeder includes a lift plate, a pickup roller, a lift motor, a retard roller, and a control unit. In a manual feed mode, the control unit rotates the retard roller to feed a document in a document conveyance direction. Further, the control unit causes the lift motor to start lowering the lift plate while the pickup roller is feeding a document after starting to rotate the pickup roller. When there is a document set on the lift plate at the time when the pickup roller stops, the control unit automatically resumes the feeding in the manual feed mode.
US11459195B2 Original reading apparatus
An original reading apparatus includes a reading unit, a pick-up roller, a feed roller, a conveyance roller, a conveyance motor, a clutch, and a controller unit to control the clutch and the conveyance motor such that the pick-up roller and the feed roller that receive a driving force from the conveyance motor rotate at a given rotation speed. The rotation speed is set to a first speed when reading an original having a first size at a first resolution, to a second speed higher than the first speed when reading an original having the first size at a second resolution lower than the first resolution, and to a third speed lower than the second speed, regardless of designation of the reading resolution, when reading an original having a second size smaller than the first size.
US11459192B2 Container supply device and container supply method
A container supply device includes a guide plate that guides stacking of a plurality of lids in a vertical direction, a lower claw capable of advancing/retreating and mounting a first container located at the lowermost position in a plurality of stacked containers, an upper claw capable of advancing/retreating and including a recess into which a flange portion of a second container sequentially stacked on the first container in the plurality of stacked containers is inserted, and a suction pad that adsorbs and separates the first container from the second container in a state where the second container is supported by the upper claw.
US11459190B2 Systems and methods for die transfer
In certain embodiments, a system includes: a source lane configured to move a first die container between a load port and a source lane staging area; an inspection sensor configured to produce a sensor result based on a die on the first die container; a pass target lane configured to move a second die container between a pass target lane out port and a pass target lane staging area; a fail target lane configured to move a third die container between a fail target lane out port and a fail target lane staging area; and a conveyor configured to move the die from the first die container at the source lane staging area to either the second die container at the pass target lane staging area or the fail target lane staging area based on the sensor result.
US11459187B2 Method and device for aligning rectangular packaging boxes
A method for aligning rectangular packaging boxes comprises the steps of conveying packaging boxes along a transport path and of aligning each packaging box by means of at least one stop element. The step of aligning a packaging box comprises the steps of positioning the at least one stop element in a first position, in which it projects into the transport path; conveying the packaging box against the at least one stop element until each section of the packaging box facing the at least one stop element is resting against it; and moving the at least one stop element into a second position, in which it does not project into the transport path and thus releases the aligned packaging box for further transport.
US11459184B2 Mass shaped detaching razor device and system thereof
A mass shaped detaching razor device for detaching mass shapes from a laminating roller without damaging the same is provided, said device comprises a main support coupled on its upper section with a lower end of a pressure arm by means of a 5 pivot coupling, the main support is coupled on its lower section with a razor support having on a frontal end a detachment razor, a shock absorber coupled on its lower end to a back end of the main support and coupled by its upper end to an upper end of the pressure arm.
US11459179B2 Vertical dough conveyor
A vertical dough conveyor includes a base frame, and a vertical conveyor assembly pivotably connected to the base frame for pivoting movement between a use position and an access position. The vertical conveyor assembly includes a first conveyor belt unit and a second conveyor belt unit, wherein the second conveyor belt unit is pivotably connected to the first conveyor unit such that, when the vertical conveyor assembly is in the access position, the first conveyor belt unit is pivotably movable between a first position and a second position. In the first position, a belt of the second conveyor belt unit is positioned in opposed relation to a belt of the first conveyor belt unit to define a dough feed gap therebetween. In the second position, the belt of second conveyor belt unit is pivoted away from the belt of the first conveyor belt unit.
US11459174B1 Portable air-tight water-tight reusable trash receptacle
A system and method for preventing leaks from rubbish containing liquids and noxious smells has an air-tight and water-tight reusable trash receptacle. The receptacle uses an inner ring and an outer ring to secure a trash bag. A lid contains a seal such that an air-tight and water-tight seal is formed when the lid is engaged with the outer ring. The outer ring has a seal that engages the trash bag such that an air-tight and water-tight seal is formed when the outer ring is engaged with the liner on the inner ring. A fabric cover attaches to the outer ring and protects and hides the trash bag held within. The lid is attached to the outer ring in a variety of ways, including hinges, threads, tether, and tabs. The outer ring secures to the inner ring in a number of ways including threads, clips, and tabs.
US11459171B2 Locking device
The present invention generally relates to waste containers and, more particularly, relates to a locking device for waste containers. The locking device is gravity actuated to an opened position on tilting of the container for dumping. The locking device allows the lid of the container, when the container is in an upright position, to be locked to prevent unauthorized access to the container. When the container is tilted from the upright position, e.g. to empty the contents of the container, the locking device is gravity actuated to allow the lid to open.
US11459168B2 Single-portion package, use, and preparation machine
The invention relates to a single-portion package (1) for producing a beverage from a beverage concentrate, comprising a closable concentrate container (2) for holding the beverage concentrate. According to the invention, the single-portion package (1) has an extraction and mixing device (3), comprising: an extraction means (4a, 4b) for extracting the beverage concentrate from the concentrate container (2), a mixing chamber (5) for preparing the beverage from the beverage concentrate extracted from the concentrate container (2) and from a mixing liquid that can be supplied, an inlet (6) for letting the mixing liquid into the mixing chamber (5), and an outlet (7) for letting the beverage out of the mixing chamber (5).
US11459167B2 Pouch container containing a beverage and exterior sheet material therefor
A pouch container generating hydrogen water is provided. A beverage containing at least water and a hydrogen generating substance that reacts with water to generate hydrogen gas are contained in a pouch container that is sealed. Even when hydrogen in a gas form leaks from a sealed part or the like of the pouch container to the outside, new hydrogen gas is generated by the reaction of the water and the hydrogen generating substance in the pouch container. Hydrogen water having sufficient hydrogen gas dissolved therein can be provided even after the long-term preservation. For example, the hydrogen generating substance may be contained in a straw or may be kneaded into an exterior sheet material.
US11459164B2 Pill dispenser
The invention relates to a pill dispenser (1), which has a sleeve (2) and a magazine (3) guided in this sleeve (2) to hold a stack of pills. For filling purposes, the magazine can be partially pushed out of the sleeve (2) in the longitudinal direction (4) of the magazine against the force of a spring (5) and receives at its upper end a cap (6) in a pivotally adjustable manner, which cap (6) is pivotally adjustable against the force of a spring (7) from a rest position into a dispensing position and supports a decorative head (8). In order to create advantageous fastening conditions for the decorative head, it is proposed that the cap (6) has a transverse guide (9) onto which the at least two-part, in particular at least two-shell, decorative head (8) is pushed transversely to the longitudinal direction (4) of the magazine.
US11459160B2 Packaging box and container
The present application discloses a packaging box and a container, the packaging box includes a box body and a desiccant, the box body includes a bottom plate and a side wall, where the bottom plate and the side wall form a cavity for holding a product, a desiccant groove is provided in the side wall, the desiccant groove includes an opening in communication with the cavity, and an anti-gipping structure is disposed at the opening.
US11459155B2 Pallet container with drainage tube
A pallet container for storage and for transportation of liquid or free-flowing contents has a thin-walled, rigid plastic inner container composed of thermoplastic material, having a tubular lattice frame, which, in the form of a supporting jacket, tightly encloses the plastic inner container and which is composed of horizontal and vertical tubular bars which are welded to one another, and having a rectangular bottom pallet, on which the plastic inner container bears and to which the tubular lattice frame is firmly connected.
US11459147B2 Grip container system
A food packaging container is provided. The container comprises a molded body defining a longitudinal axis, and including a plurality of sides and a plurality of axial corners. Each corner has a recess including a first portion and a second portion. Each of the first portions includes an axial grip surface where the grip surfaces are aligned with the body in an orientation for gripping. In some embodiments, packaging products, containers, handles, tooling, applicators and methods are disclosed.
US11459143B2 Integrated, portable and hybrid package and carrier
Embodiments disclosed herein relate to a hybrid package and carrier system. The system can include a container for storing a plurality of items set at a first position, wherein the container is configured with a trapezoidal configuration. The system can also include the plurality of items set at a second position, wherein the plurality of items are positioned within the container to enable the container to store the plurality of items. Further, the system can include a cover set at a third position with a trapezoidal shape, wherein the cover is positioned over the container to protect the plurality of items stored in the container. The system can also include a handle configured to an exterior portion of the cover with the trapezoidal shape, wherein the handle is set to lift the cover along with the plurality of items stored within the container in a vertical direction.
US11459142B2 Carton with first hinge panel and second hinge panel
The carton includes a back panel, a first inner panel, a first surface of the first inner panel contacting a second surface of the back panel, and walls positioned on sides of the back panel, the walls, the back panel and the first inner panel collectively defining a recess. The walls includes a first hinge panel connecting a top panel to the back panel, a second hinge panel connecting a bottom panel to the back panel, a first side panel and a second side panel each connected to the back panel, a top front panel connecting a second inner panel to the top panel, a third surface of the second inner panel contacting the second surface of the back panel, and a fourth surface of the first hinge panel and a fifth surface of the second hinge panel connected to the back panel.
US11459135B2 Method and apparatus for packing product in a tubular casing
A method and apparatus of packing product in a tubular casing is provided. The method includes providing a continuous length of tubular casing, providing an expansion plug within the tubular casing, grasping the casing upstream end with a casing grabber, moving the casing grabber away from the expansion plug towards an outlet end of a product feed conduit, feeding product from the product feed conduit through the casing upstream end into the tubular casing, and cutting the tubular casing downstream of the product to sever an upstream casing segment from the remaining continuous length of tubular casing.
US11459134B2 Thermoforming packaging machine with space-saving film source
A thermoforming packaging machine comprises a film source, a forming station, a sealing station and a conveying device. The film source is configured to receive a lower film supply roll and provide a lower film web unwound from the lower film supply roll. The conveying device is configured to convey the lower film web from the film source to the forming station and further to the sealing station. The film source comprises a holding mandrel for receiving thereon the lower film supply roll and a film storage device configured for accommodating a variable length of the lower film web and regulating a film tension of the lower film web. The holding mandrel and the film storage device are arranged one above the other in a vertical direction.
US11459133B2 Method of aligning a spacecraft frame
A method is provided for realigning or relieving mechanical stress in a spacecraft frame. The process includes providing a spacecraft which includes at least two frame subsections connected by a mechanical connector. The mechanical connector provides both a soft dock connection which mechanically connects the two frame subsections but allows relative movement between the two frame sections and a hard dock connection which mechanically connects the two frame subsections but does not allow relative movement between the two frame sections. Once in space, a controller causes the mechanical connector to transition from a hard dock connection to a soft dock connection, which is maintained for a predetermined time period to realign or relieve stress within the spacecraft frame. Thereafter, the controller causes the mechanical connector to transition from the soft dock connection back to the hard dock connection.
US11459131B2 Satellite with a thermal switch and associated methods
A satellite includes a satellite housing, a temperature sensitive component carried by the satellite housing, and a thermal radiator carried by the satellite housing. A thermal switch is movable between a coupled state and a decoupled state. In the coupled state, the temperature sensitive component and the thermal radiator are thermally coupled. In the decoupled state, the temperature sensitive component and the thermal radiator are thermally decoupled.
US11459130B2 Integration of fuel cell with cryogenic source for cooling and reactant
A fuel cell-based power system comprises a fuel cell configured for continuously receiving a first reactant and a second reactant to produce chemical reactions that generate electrical power, water, and heat, a coolant subsystem configured for circulating a primary coolant in association with the fuel cell, thereby absorbing the generated heat, a tank configured for storing a reactant, and a reactant distribution subsystem configured for conveying the reactant from the tank to an independent system, the fuel cell as the first reactant, and the coolant subsystem as a secondary coolant to remove the absorbed heat from the primary coolant and/or a water accumulator. The secondary coolant may be conveyed to a gas thruster as a gas after the absorbed heat has been removed from the secondary coolant. The reactant may boil off of a cryogenic liquid or vapor or gas transformed from a cryogenic liquid via a heater.
US11459124B2 Assembly tool for fuselage structure splice
An apparatus for mounting a splice component for joining two or more workpieces includes a base plate and one or more bias assemblies. The base plate includes one or more passageways extending through the base plate and one or more barrier elements mounted proximate to the passageway(s). Each barrier element and associated passageway are configured to freely receive a protrusion of a splice component. The bias assembly includes a bias element that extends proximate to the passageway and is configured to move resiliently to urge the protrusion against the barrier element. The passageway, the barrier element, and the bias assembly are configured to allow movement of the splice component relative to the base plate transverse to a direction of force applied by the bias element on the protrusion.
US11459122B2 Modular floor system for large vehicle construction
A modular floor system with an integral utility for temporary installation in an unfinished aircraft fuselage to facilitate construction. The system includes multiple floor modules, each including a catch pan defining a pan volume, a grid top surface supported on the catch pan over the pan volume, and a utility manifold carrying a utility across the module and to the next module. The modules may be sized and shaped to conform to different installation locations within the vehicle body. The grid top surface is openable to access the pan volume to remove debris or items. Adjacent modules are coupled together with connectors. The utility may be vacuum, air, electricity, or water, and one manifold may carry air and another manifold may carry vacuum. A fixture may be connected to the vacuum manifold and receive an end of a drill so as to remove debris resulting from operation of the drill.
US11459120B2 Control device, control device system, runway flash lighting device control system, program, and recording medium
A control device includes: a control signal transmitter transmitting a signal to a controlled device; a control signal receiver receiving a signal from the controlled device; a control signal generator generating a control signal of 2 bytes or more in one transmission cycle, in which an address is assigned to each byte, is ON/OFF switchable, and includes a main signal address and a collation signal address; and a control signal controller that, when the main and collation signal addresses are the same address, turns the collation signal address ON when the main signal address is ON and turns the collation signal address OFF when the main signal address is OFF, and when the main and collation signal addresses are inverted, turns the collation signal address OFF when the main signal address is ON and turns the collation signal address ON when the main signal address is OFF.
US11459119B2 Installation and method for controlling signalling lights arranged in series
An installation powers and controls a plurality of signaling lights arranged in series, each having at least one light source. The installation includes a unit with a primary power supply situated upstream for remotely programming or managing operation of the installation; a primary series circuit with a transformer for each signaling light; a control module for each signaling light; a secondary power supply circuit for powering the control modules, independent of the primary circuit; a first optical cable for bi-directionally connecting a first upstream module to the programming or managing unit; and a second optical cable for bi-directionally connecting a last downstream control module to the programming/management unit, with each control module being connected in series to an adjacent upstream module and to an adjacent downstream module by means of a respective bi-directional optical connection.
US11459118B2 Protective cover for an aircraft comprising electromagnets
A protective cover for the protection of an aircraft having a fuselage and two wings, includes an anchoring system fixing the protective cover to the aircraft, a tarpaulin having a retracted position wherein it is gathered up and a deployed position wherein it is spread over the wing, a deployment device making the tarpaulin move from the retracted to the deployed position, an electromagnet fixed to the tarpaulin face against the wing, and having a deactivated state and an active state, a remote control, and a control system including a control unit in communication with the remote control. When the control unit receives activation information from the remote control, the control unit controls the deployment device, to make the tarpaulin move from the retracted position to the deployed position, and activates each electromagnet. When the control unit receives deactivation information from the remote control, the control unit deactivates each electromagnet.
US11459109B2 Automatic aircraft pilot seat side-stick armrest
An armrest is disclosed that includes an armrest frame rotationally coupled to a seat frame, an armrest subframe pivotably couple to a second end of the armrest frame, and an arm pad laterally aligned and translatably coupled to the armrest subframe. The armrest further includes a tilting mechanism configured to pivot the armrest subframe relative to the armrest frame. The armrest further includes a translation mechanism configured to translate the arm pad relative to the armrest subframe. The armrest further includes a rotation mechanism configured to rotate the armrest relative to the seat frame. At least one of the tilting mechanism, the translation mechanism, or the rotation mechanism includes a spring-loaded linkage.
US11459108B2 Life vest container device
The invention relates to a life vest container device, in particular aircraft seat life vest container device, for a life vest unit, with a life vest container comprising an accommodation unit that has an accommodation space as well as an access opening to the accommodation space, and with a monitoring device.It is proposed that the monitoring device is at least configured to capture a change of at least one characteristic via at least one electric and/or electronic signal.
US11459106B2 Aircraft water supply system
An aircraft water supply system supplies water to a water discharge port in an aircraft. A cold water flow path supplies cold water to the water discharge port. A hot water flow path supplies hot water to the water discharge port. A first control valve adjusts the flow rate of cold water flowing through the cold water flow path. A second control valve adjusts the flow rate of hot water flowing through the hot water flow path. A flow sensor detects the flow rate of water at any point up to the water discharge port. A flow control unit controls the opening/closing state of the first control valve and the second control valve based on the water temperature detected by the flow sensor so that the amount of the water discharged from the water discharge port reaches a predetermined target flow rate.
US11459101B2 Method of flying unmanned aerial robot in unmanned aerial system and apparatus for supporting the same
A method of analyzing a propeller status of a wireless aerial robot can include measuring status information related to the propeller status by a sensor of a propeller; determining whether an operation of the propeller is abnormal based on the status information; transmitting the status information and operation information regarding whether an operation of the propeller is abnormal to a control unit using short range wireless communication; and analyzing, by the control unit, a flight status of the wireless aerial robot based on the status information and the operation information regarding whether the operation of the propeller is abnormal.
US11459097B2 Erosion protection coating with screen
The present invention includes an apparatus for protecting an aerodynamic surface from erosion including a screen capable of being applied to a leading edge of the aerodynamic surface; and an erosion protection coating applied to the screen before or after the screen is applied to the leading edge, wherein the erosion protection coating protects the aerodynamic surface from erosion.
US11459092B2 Aircraft steering system, aircraft, and aircraft steering method
An aircraft steering system includes an electric actuator, a clutch, at least one plasma actuator, and a controller. The electric actuator is configured to vary an angle of a flight control surface of an aircraft. The clutch is configured to cut off torque by driving of the electric actuator. The torque is to be transmitted to the flight control surface. The at least one plasma actuator is configured to form a flow of air on a surface of the flight control surface when the torque is cut off. The controller is configured to control the electric actuator, the clutch, and the at least one plasma actuator.
US11459085B2 Energy attenuation stabilizers and methods
According to one implementation of the present disclosure, a stabilizer of an aircraft includes an energy attenuating portion. The energy attenuating portion includes first and second edge sections separated by an adaptable section. The adaptable section may be rigid in a first range of directions and compressible in a second range of directions.
US11459084B2 Wing for an aircraft
A wing for an aircraft, comprising a fixed wing, a foldable wing tip portion mounted to the fixed wing via a first hinge rotatably about a first hinge axis between an extended and folded positions, and an actuation unit to actuate the foldable wing tip portion for movement about the first hinge axis. The actuation unit comprises a link, a first and a second linear actuator. The link is rotatably mounted to the fixed wing via a second hinge, the first linear actuator is rotatably mounted to the fixed wing via a third hinge spaced from the second hinge, and is rotatably mounted to the link via a fourth hinge spaced from the second hinge. The second linear actuator is rotatably mounted to the foldable wing tip portion via a fifth hinge, and is rotatably mounted to the link via a sixth hinge spaced from the second hinge.
US11459080B2 Transformable stratospheric airship
A transformable stratospheric airship includes an upper shell, a lower shell, a foldable hull, and a plurality of cable control mechanisms provided on the upper shell and the lower shell. The foldable hull includes a sealed body, a plurality of guide holes arranged outside the sealed body and a cable which passes through the guide holes according to a predetermined order. The cable is configured to keep a shape of the sealed body and connected to the cable control mechanisms to fix the sealed body to the upper shell and the lower shell. The foldable hull is foldable and extendable along a vertical direction of the transformable stratospheric airship by controlling a length of the cable via the cable control mechanisms.
US11459079B2 Ship propulsion machine
There is provided a ship propulsion machine including: a drive shaft; a drive gear fixed to the drive shaft; a front gear meshed with the drive gear; a rear gear meshed with the drive gear; a rear propeller provided on an inner propeller shaft; a front propeller provided on an outer propeller shaft; a casing having a gear chamber; a second bearing that supports a front end side of the outer propeller shaft at a rear portion of the casing; a third bearing that supports the inner propeller shaft and the outer propeller shaft in a manner rotatable with respect to each other. The third bearing is disposed on an inner peripheral side of a shaft portion of the rear gear, and the second bearing is disposed on an outer peripheral side of the shaft portion of the rear gear.
US11459076B1 Systems and methods for controlling transmission valves in a marine propulsion device
A method for controlling a valve to disengage a gear in a transmission. The method includes reducing, after receiving a request to disengage the gear, a current supplied to the valve from a starting to a first current. The method further includes counting a first elapsed time since the valve was reduced to the first current, comparing the first elapsed time to a first wait time, and increasing the current supplied to the valve to a second current once the first elapsed time exceeds the first wait time. The method further includes counting a second elapsed time since the valve was increased to the second current, comparing the second elapsed time to a second wait time, and reducing the current supplied to the valve to a third current once the second elapsed exceeds the second wait time. The valve is closed when the current is the third current.
US11459075B2 Drive for a boat with electric motor
A drive for a boat includes a housing that is arranged underwater during operation, and that houses an electric motor that drives a propeller. The housing includes a cooling section that includes a coolant duct.
US11459074B1 Marine drives and methods of making marine drives so as to minimize deleterious effects of cavitation
A method is for making a marine drive for propelling a marine vessel in water. The method includes providing a gearcase; installing a propeller shaft assembly that extends forwardly from the gearcase; coupling front and rear propellers to the propeller shaft assembly, forwardly of the gearcase, such that rotation of the propeller shaft assembly causes rotation of the front and rear propellers, respectively, which thereby propels the marine vessel in the water; and reducing deleterious effects of cavitation on the gearcase by the combination of forming the gearcase with a wide trailing end portion, in particular to maintain pressure alongside the gearcase, and configuring the front and rear propellers so that the front propeller absorbs more torque/thrust load than the rear propeller during said rotation.
US11459070B2 Posture control system for hull, posture control method for the hull, and marine vessel
A posture control system for a hull offers a more comfortable ride to crew on a marine vessel. A posture control tab is mounted on a stern of the hull and controls the posture of the hull. An actuator actuates the posture control tab. At least one propeller generates a propulsive force for the hull. An engine turns the propeller. A controller controls the actuator according to at least one of engine torque generated by the engine and propeller torque generated by the propeller.
US11459061B2 Bicycle component motion control
Bicycle component motion control begins when a motorized bicycle component is commanded to shift or actuate. The bicycle component motion control compares parameters of a component of the bicycle to be moved, to predetermined thresholds to provide safe shifting or actuation. The shift or actuation starts only when the battery voltage and the battery temperature are within predetermined acceptable ranges, respectively. Once the shift or actuation has started, the shift or actuation is aborted if the battery voltage remains below a predetermined low voltage threshold for a predetermined amount of time. If the shift or actuation is aborted when the component is in a position, in which the bicycle may not operate at a particular level or is inoperable, the shift or actuation command is modified to move the component to a previous position or an intermediate position.
US11459057B2 Adjustable axle retaining structure
An adjustable axle retaining structure is disclosed. The structure includes an axle receiving feature on a first leg of a fork assembly and a retaining sleeve within a clamping member on a second leg of the fork assembly. An axle is inserted through the clamping member, the wheel hub and coupled with the axle receiving feature. A component of the axle is tightened thereby moving the retaining sleeve partially out of the clamping member and toward the wheel hub until the wheel hub is in contact with both the retaining sleeve and the axle receiving feature, wherein the moving of the retaining sleeve allows the axle to radially couple the wheel hub with the fork assembly without modifying a preestablished geometry of the fork assembly.
US11459053B2 Electric vehicle
An electric self-balancing vehicle including a top cover, a bottom cover, an inner cover, a rotating mechanism, two wheels, two hub motors, a plurality of sensors, a power supply, and a controller is described herein. The top cover includes a first top cover and a second top cover disposed symmetrically and rotatable relative to each other. The bottom cover is fixed to the top cover and includes a first bottom cover and a second bottom cover disposed symmetrically and rotatable relative to each other. The inner cover is fixed between the top cover and the bottom cover and includes a first inner cover and a second inner cover disposed symmetrically and rotatable relative to each other. The rotating mechanism is fixed between the first inner cover and the second inner cover. The two wheels are rotatably fixed at two sides of the inner cover, respectively. The two hub motors are fixed in the two wheels, respectively. The plurality of sensors is disposed between the bottom cover and the inner cover, respectively. The power supply is fixed between the first bottom cover and the first inner cover. The controller is fixed between the second bottom cover and the second inner cover, the controller is electrically connected with the plurality of sensors, the power supply, and the hub motors, and the controller controls the hub motors to drive the corresponding wheels to rotate according to sensing signals transmitted by the sensors.
US11459052B2 Control method for use with longitudinal motion-sensing two-wheeled vehicles and control system
A control method for use with longitudinal motion-sensing two-wheeled vehicles is provided. The control method includes: collecting posture data of a human body leaning forward and backward and controlling an output of a circuit drive module to thereby control a rotational output of a motor; a motor rotor of the motor outputting a movement vector and an acceleration to control a rotation of wheels under the control of the output of the circuit drive module, a motor stator receiving a reaction force during a rotating and outputting process of the motor rotor, and the reaction force being transmitted to a motion-sensing platform through a mechanical structure by the motor stator, and the motion-sensing platform transferring and feeding back the reaction force to a user standing on the motion-sensing platform, thereby adjusting posture data of the motion-sensing platform again by means of a human body posture to achieve a motion-sensing balance control.
US11459051B2 Gerbilling-proof mono wheel vehicle
A gerbilling-proof monowheel vehicle comprises: (a) a wheel felloe with a tire thereon; (b) a frame rotatably mounted within the wheel felloe; the frame carrying a passenger seat; (c) moving means configured for propelling the gerbilling-proof monowheel vehicle; and (d) braking means configured for decelerating the gerbilling-proof monowheel vehicle. The gerbilling-proof monowheel further comprises at least two auxiliary wheels side-mounted on the frame for vertically stabilizing the passenger seat and preventing the gerbilling-proof monowheel from side tipover and maintaining said passenger seat in a horizontal position within said wheel felloe.
US11459047B2 Tolerance compensation system for setting a joint pattern between two outer trim elements to be mounted in the region of a vehicle pillar of a motor vehicle
A tolerance compensation system for setting a joint pattern between two outer trim elements to be mounted on respective door frames in the region of a vehicle pillar of a motor vehicle. The tolerance compensation system includes a set of tolerance compensation elements which are insertable into respective cutouts in the door frame and which each have a receiving region for receiving the outer trim elements. The set has at least two different variants of the tolerance compensation elements which differ in terms of the positioning of their respective receiving regions in order to set the joint pattern or the set has only one variant of the tolerance compensation elements in which the receiving region is arranged eccentrically and the tolerance compensation elements are insertable into the cutouts in the door frames in two positions rotated through 180° with respect to one another in order to set the joint pattern.
US11459046B1 Service table for transporting a battery pack of a motor vehicle along a floor surface
A service table for transporting a battery pack comprises four frame members arranged end-to-end in a circuit, four hinges between adjacent frame members, and wheels. The service table further comprises a support bed mounted to at least one of the frame members and configured to support the battery pack. At least one hinge lock is disposed between adjacent frame members and arranged to be rigidly fixed to both of the adjacent frame members in a locked configuration and arranged to be decoupled from at least one of the adjacent frame members in an unlocked configuration. The frame members are arranged in a service configuration having a first width when the hinge lock is arranged in the locked configuration for transporting the battery pack thereon and in a storage configuration having a second width, less than the first width, when the hinge lock is arranged in the unlocked configuration.
US11459039B2 Vehicular under cover
A vehicular under cover includes an oblong hole-shaped through-hole and is assembled to a lower side of a vehicle so as to cover a lower part of the heat source. In a plan view, the through-hole is formed so that a longitudinal direction of the through-hole is inclined with respect to a front-rear direction of the vehicle. The inclination excludes an orthogonal direction to the front-rear direction of the vehicle.
US11459036B2 Vehicle body front structure
Provided is a vehicle body front structure including a front hood (7) provided in a front part of a vehicle body (3), and a port device (30) mounted to the vehicle body and positioned under the front hood. The front hood includes an outer panel (7A) and an inner panel (7B) attached to a back side of the outer panel, the outer panel and the inner panel defining a port opening (21) facing the port device and passed through the outer panel and the inner panel in a thicknesswise direction thereof, and being welded to each other along a peripheral edge (22) of the port opening, and a garnish (23) is provided on an outer surface of a peripheral part of the outer panel surrounding the port opening, and a lid (58) for selectively closing the port opening is provided on the vehicle body.
US11459032B2 Trailer assembly
A trailer assembly with improved lateral support structure and steering system control of the axial wheels on a front elongated trailer and a rear elongated trailer to remain in a collinear following configuration to carry elongated loads extending over the extended lengths of the combination of the front elongated trailer and the rear elongated trailer and allow ready turning control.
US11459029B2 Steering system and vehicle equipped with same
The steering system includes: a first steering device to-steer left and right wheels in a mechanically associated manner by changing an angle of left and right chassis frame components; and a second steering device to drive a supplementary turning actuator to change angles of the wheels relative to the chassis frame components. The second steering device includes a supplementary turning control section to perform a control to cause turning by a steering angle that is a difference between a steering angle determined by a numerical model of vehicle motion on the basis of the steering command angle and the vehicle velocity and an actual steering angle.
US11459027B2 Hydraulic steering arrangement
A hydraulic steering arrangement 1 is described comprising a supply port arrangement having a pressure port (4) and a tank port (5), a working port arrangement having two working ports (6, 7), a steering unit (2) arranged in a flow path (9) between the supply port arrangement (4, 5) and the working port arrangement (6, 7), and a second flow path (13) in form of an amplification flow path bridging the steering unit (2) and having an amplification orifice (AU1) which is controlled as function of the steering unit (2). Such a steering arrangement should have a possibility to change the steering behaviour. To this end at least a third flow path (14) in form of an amplification flow path is arranged in parallel to the second flow path (13), wherein the second/or the third flow path (13, 14) comprise an valve (15).
US11459026B2 Backup control of electric power steering system when sensor failure occurs
Systems and methods for controlling an electric power steering system. The system includes an electric motor configured to provide a torque to a steering mechanism of a vehicle, a torsion bar torque sensor, a vehicle speed sensor, and a steering angle sensor. The system also includes an electronic controller configured to determine a failure of the torsion bar torque sensor, receive a vehicle speed from the vehicle speed sensor and a steering angle from the steering angle sensor, calculate a steering assistance torque based on the vehicle speed and the steering angle, calculate a hysteresis torque based on the steering angle, sum the steering assistance torque and the hysteresis torque to determine a turning torque, calculate a return torque and sum the turning torque and return torque to obtain an output torque, and generate a command for the electric motor to provide the output torque to the steering mechanism.
US11459025B2 Detection unit
In a detection unit, a control unit includes an abnormality monitoring unit and a control calculation unit, and obtains an angle signal from different sensor units. The abnormality monitoring unit monitors abnormality of the angle signal. The control calculation unit performs calculation by using the angle signal. A second control unit obtains the angle signal by communication with a first control unit, i.e., from an other control unit. The abnormality monitoring unit, when comparing a subject system calculation value with an other system calculation value, uses a communication delay corrected value which has a correction of communication delay as at least one of the subject system calculation value and the other system calculation value.
US11459019B2 Vehicle steering apparatus
A vehicle steering apparatus, including: a steering column; a link member; an actuator including: a vehicle body side engaging portion, and a link side engaging portion, and when operated, the actuator changing a spacing between the vehicle body side engaging portion and the link side engaging portion, and swinging the steering column between the first position and the second position; a steering support that supports the steering column from the vehicle lower side in a state in which the steering column is disposed at the first position; and a clamp member provided at the link member, the clamp member being engaged with the steering support in the state in which the steering column is disposed at the first position, and the clamp member moving away from the steering support when the steering column is to swing from the first position toward the second position.
US11459017B2 Energy absorption device for a steering column, steering column and method for operating a steering column
An energy absorption device for a steering column for a motor vehicle includes an energy absorption element for absorbing energy by a relative movement between at least two components of the steering column in a crash situation, and at least one arresting element for arranging in a blocking position for blocking the relative movement.
US11459009B2 Shopping bag
A shopping bag includes a main bag body, two fixing bar members, and at least one hanger member. The main bag body includes two opposite fixing segments and two opposite connecting segments interconnected between the two fixing segments. The two fixing bar members are attached respectively to the two fixing segments. The at least one hanger member includes a housing formed with a fixing groove that is secured with one of the fixing bar members and a respective one of the fixing segments of the main bag body, and first and second retaining grooves. One of the first and second retaining grooves is adapted to be engaged detachably with a longitudinal frame member of a shopping cart.
US11459008B2 Container assembly
Provided are container assemblies, including at least two containers detachably attached to one another by locking arrangements.
US11459006B2 Modular lamp system for railroad crossing warning device
A modular lamp system (200) for a railroad crossing warning device includes a crossing lamp (210) and a crossing lamp base (220) controllable by a wayside control device (40), and a module (230) comprising an electronic circuit (250), wherein the crossing lamp base (220) is configured to provide power to the crossing lamp (210) and the module (230), and wherein, when the crossing lamp (210), the crossing lamp base (220) and the module (230) are assembled and in operation, the crossing lamp (210) performs a first action and the module (230) performs a second action, which is different from the first action.
US11459002B2 Methods and systems for dynamic weight management
Systems and methods for reducing slack in a linkage chain of a vehicle truck assembly is provided. In one example, a method includes compressing a vehicle suspension by actuating an actuator with a cylinder abutted to a piston rod, the piston rod coupled to the vehicle suspension and, when deactivating the actuator, maintaining at least nominal compression on the vehicle suspension with the piston rod spaced away from a piston of the cylinder via a biasing member, the piston configured to slide within the cylinder along a central axis of the cylinder.
US11459000B2 Deflector for vehicle
A deflector for use with railcars and containers. The deflector may be used to retrofit railcars and other container to reduce aerodynamic drag. The deflector may be collapsible for use with stacked containers.
US11458998B2 Information processing apparatus, information processing method and non-transitory storage medium
A control unit of a server device as an information processing apparatus is configured to: provide first information on a service for each of a plurality of moving objects, each of which is configured to provide a different service and autonomous travel; acquire second information on time and location of at least one service that a user wants to use; and determine at least one moving object that matches with the user based on the first information and the second information, and generate a travel plan of the at least one moving object.
US11458997B2 Autonomous vehicle computing system with processing assurance
Systems and methods are directed to a method for assured autonomous vehicle compute processing. The method can include providing sensor data to first and second functional circuitry of an autonomy computing system. The first and second functional circuitry can be configured to generate first and second outputs associated with a first autonomous compute function. The method can include generating, by the first and second functional circuitry in response to the sensor data, first and second output data associated with the first autonomous compute function. The method can include generating, by monitoring circuitry of the autonomy computing system, comparative data associated with differences between the first output data and the second output data. The method can include generating one or more vehicle control signals for the autonomous vehicle based at least in part on the comparative data.
US11458995B2 Passenger health screening and monitoring
Among other things, techniques are described for screening and monitoring the health of a vehicle user including receiving sensor data produced by a sensor at the vehicle, processing the sensor data to determine at least one health condition of the user of the vehicle, and in response to determining the at least one health condition, executing a vehicle function selected from a plurality of vehicle functions based on the at least one health condition.
US11458987B2 Driver-centric risk assessment: risk object identification via causal inference with intent-aware driving models
A system and method for predicting driving actions based on intent-aware driving models that include receiving at least one image of a driving scene of an ego vehicle. The system and method also include analyzing the at least one image to detect and track dynamic objects located within the driving scene and to detect and identify driving scene characteristics associated with the driving scene and processing an ego-thing graph associated with the dynamic objects and an ego-stuff graph associated with the driving scene characteristics. The system and method further include predicting a driver stimulus action based on a fusion of representations of the ego-thing graph and the ego-stuff graph and a driver intention action based on an intention representation associated with driving intentions of a driver of the ego vehicle.
US11458986B2 System and method for providing driving assistance to safely overtake a vehicle
Various aspects of a system and method to provide driving assistance to safely overtake a vehicle are disclosed herein. In accordance with an embodiment, an electronic control unit used in a first vehicle is configured to detect a second vehicle in front of the first vehicle. A first position associated with the first vehicle and a second position associated with the detected second vehicle is determined for a first time instance. It may be determined whether a lateral distance between the determined first position and the determined second position is below a pre-defined threshold distance. A first alert is generated when the determined lateral distance is below the pre-defined threshold distance.
US11458985B2 Method, device, and computer program for the operation of a vehicle operation system
A method for operating a vehicle operating system, wherein a navigation system provides map information, and a monitoring system monitors driver assistance information, which are displayed on a display device, wherein the navigation system, the monitoring system, the display device, and an operating device are coupled to a control device for data transfer, to display the map information and/or driver assistance information on the display, wherein an operating action is carried out by the operating device in order to change a display scale and/or a display angle in relation to a road surface between a first perspective and a second perspective, wherein the display scale and/or angle are adjusted continuously and/or discretely in at least two steps located within the two perspectives on a virtual visualization path, and wherein the first perspective is substantially perpendicular to the road surface and the second perspective is substantially parallel to the road surface.
US11458981B2 Autonomous vehicles and methods of using same
A vehicle includes one or more sensors arranged on at least one of a dashboard, a roof, and a center console of the vehicle, or one or more image capturing devices for capturing one or more images from a left side and a right side of the vehicle, an electronic control unit (ECU) configured to communicate with the one or more sensors or the one or more image capturing devices, and at least one of a morphing surface, a windshield display, and one or more displays configured to be controlled by the ECU, where the one or more sensors are arranged under a black panel surface.
US11458979B2 Information processing system, information processing device, information processing method, and non-transitory computer readable storage medium storing program
An information processing system includes an acquisition unit configured to acquire traveling information indicating traveling conditions of a first vehicle traveling on a road, a determination unit configured to determine one or more driving operations of a driver driving the first vehicle by using the traveling information acquired when a second vehicle approaches the first vehicle, an evaluation unit configured to perform evaluation of safety related to the driver's driving by using determination results of the determination unit, and an updating unit configured to acquire first evaluation results of the evaluation unit during a first predetermined period to compare the first evaluation results with second evaluation results of the evaluation unit during a second predetermined period before the first predetermined period, and to update the second evaluation results based on comparison results.
US11458977B2 Driving load estimation apparatus
A driving load estimation apparatus can estimate the driving load of individual drivers in accordance with the driving environment. The driving load estimation apparatus can include a first VACP calculator configured to calculate a first VACP value based on information related to a driving environment of a vehicle and a correction value calculator configured to calculate a VACP correction value of each driver based on a steering operation in the driving environment. The driving load estimation apparatus estimates a driving load of the driver by correcting the first VACP value based on the VACP correction value.
US11458974B2 Fleet-based average lane change and driver-specific behavior modelling for autonomous vehicle lane change operation
Systems and methods are provided for creating more organic lane change models for autonomous or semi-autonomous operation of a vehicle. A plurality of data associated with a plurality of driver-performed lane change maneuvers is collected from a plurality of different vehicle. Driver-performed lane change maneuvers are discarded when determined to fall outside a threshold of safety. A generic model is generated from the non-discarded data for average lane change maneuvers. Specific models can be generated for different drivers, vehicle types, and other metrics by comparison with the generic model.
US11458972B2 Vehicle control apparatus
A vehicle control apparatus is disclosed. The vehicle control apparatus includes a distance sensor configured to sense a distance from a speed bump, a speed sensor configured to sense a speed of a vehicle, a vehicle driver configured to control an operation of a brake or an operation of an accelerator, and a processor configured to provide an input parameter comprising a speed and a weight of the vehicle to a prediction model and control the vehicle driver so that the brake is operated at a braking intensity outputted from the prediction model when the vehicle enters the speed bump on the basis of the distance from the speed bump.
US11458971B2 Apparatus for controlling platooning and method thereof
An apparatus for controlling platooning and a method thereof are provided. The apparatus includes a communication part to transmit or receive information on the platooning and information on a restricted area from or to vehicles in a platooning line and a vehicle external server. The apparatus further includes a processor to restrict an inter-vehicle distance from being increased or an acceleration when a leading vehicle in the platooning line enters the restricted area based on the information on the restricted area.
US11458969B2 Vehicle control device, and vehicle
A vehicle control device which controls acceleration/deceleration of a vehicle includes: a switch controller; a recognizer; an actual vehicle-to-vehicle distance calculator; and a target vehicle-to-vehicle distance calculator. Switching criteria for the switch controller's switching the control condition from the first control condition to the second control condition include a criterion that the absolute value of a difference between an actual vehicle-to-vehicle distance calculated by the actual vehicle-to-vehicle distance calculator and a target vehicle-to-vehicle distance calculated by the target vehicle-to-vehicle distance calculator is less than or equal to a predetermined threshold.
US11458968B2 Braking/driving force control system
A braking/driving force control system, during control for maintaining a target vehicle speed, performs fuel cut and then, when a required braking/driving force for maintaining the target vehicle speed reduces, makes a downshift while fuel cut is continued. The braking/driving force control system causes a brake to generate a braking force such that the sum of a braking/driving force that a powertrain generates and the braking force that the brake generates agrees with the required braking/driving force. Thus, good fuel efficiency and riding comfort are obtained.
US11458962B2 Automatic parking system
An automatic parking system park autonomous driving vehicles in a target parking space in a parking lot by instructing the autonomous driving vehicle in the parking lot. The system includes: a failure type determination unit configured to determine a failure type from among a plurality of preset failure type candidates, when a vehicle-induced failure occurs in an automated vehicle under autonomous driving in accordance with the instruction, an evacuation space determination unit configured to determine an evacuation space based on the failure type determined by the failure type determination unit, the position information of the autonomous driving vehicle, and the parking lot map information, and a vehicle instruction unit configured to execute an evacuation instruction to evacuate the autonomous driving vehicle to the evacuation space.
US11458961B2 Vehicle parking assist apparatus
A vehicle parking assist apparatus acquires a camera image when the vehicle stops by a non-determined parking lot and acquires feature points of a ground of an entrance of the non-determined parking lot as non-compared entrance feature points from the camera image. The vehicle parking assist apparatus determines whether the non-determined parking lot is a registered parking lot by comparing information on the non-compared entrance feature points with registered entrance feature point information. The vehicle parking assist apparatus executes a parking assist control with using the currently-acquired parking lot information and the registered parking lot information when the vehicle parking assist apparatus determines that the non-determined parking lot is the registered parking lot.
US11458960B2 Parking assistance device
The invention relates to a parking assistance device, comprising an autonomous vehicle detecting unit adapted to detect whether a parked vehicle is an autonomous vehicle (16) capable of moving autonomously, a parking space optimization area detecting unit adapted to detect at least one parking space optimization area (20), a distance measuring unit adapted to measure a distance (24) in front of or behind the at least one autonomous vehicle (16), a parking spot determining unit adapted to determine whether or not a subset of the distances (24) measured by the distance measuring unit is equal to or larger than a predetermined distance required for parking a host vehicle (26), and a communication unit (38) adapted to output a movement command to the at least one parked autonomous vehicle (16). The invention further relates to an according parking assistance method.
US11458959B2 Parking assist system
A parking assist system includes: a control device configured to control an autonomous parking operation to move a vehicle autonomously to a prescribed target parking position; and a vehicle state detecting device configured to detect a state of the vehicle. During control of the parking operation, when the control device determines that the state of the vehicle detected by the vehicle state detecting device is a prohibition state in which the parking operation should be prohibited, the control device executes a prohibition deceleration process to decelerate the vehicle so as to stop the vehicle. The control device is configured to set an upper limit on deceleration of the vehicle in the prohibition deceleration process to be larger than an upper limit on deceleration of the vehicle in a stop operation to stop the vehicle at the target parking position.
US11458956B2 Driving assistance device of vehicle connected to trailer, system including the same, and method thereof
A driving assistance device of a vehicle connected to a trailer, a vehicle system including the same, and a method thereof are provided. The vehicle driving assistance device includes a processor that determines a driving situation and a braking situation of a vehicle towing a trailer based on vehicle's internal signals and determines an amount of rear wheel steering control and an amount of braking control based on the driving situation and the braking situation of the vehicle and a storage storing the amount of rear wheel steering control and the amount of braking control, determined by the processor, and the vehicle's internal signals.
US11458951B2 Driving system
A driving system includes an engine, a motor generator, an output unit, a power transmission mechanism, and a controller. The output unit outputs at least one of an engine driving force generated by the engine or a motor driving force generated by the motor generator. The power transmission mechanism selects a first drive mode in which both of the engine driving force and the motor driving force are transmitted to the output unit, and a second drive mode in which only the engine driving force is transmitted to the output unit. The controller controls the power transmission mechanism to select the first drive mode when a first fuel consumption rate of the engine in the first drive mode is or is estimated to be lower than a second fuel consumption rate of the engine in the second drive mode.
US11458950B2 Drive force control system for hybrid vehicle
A drive force control system configured to reduce a total energy consumption of a hybrid vehicle. The drive force control system calculates: an output power of the engine which can optimize a thermal efficiency given that the engine is operated at a best fuel point; and a required electric power to be supplied from a battery or to be generated by a control motor, which can adjust the drive power established by the output power of the engine to the required power. A power exchange between the control motor and the battery is interrupted if the required electric power to be supplied from the electric storage device or to be generated by the control motor is less than a first predetermined electric power.
US11458946B2 Hybrid vehicle and method of controlling hybrid vehicle
A clutch is disengaged when a torque condition is satisfied at a predetermined time when a system is stopped as a fuel supply to an engine is stopped from a state where the engine is operating with the clutch being engaged. The torque condition is a condition under which torque acting on an output shaft of the engine is torque in a direction in which an engine speed of the engine is decreased and torque output to a rotary shaft of a motor is torque in a direction in which a motor speed of the motor is decreased.
US11458942B2 Solenoid valve, in particular for slip-controlled motor-vehicle brake systems
An electromagnetic valve whose inlet and outlet ducts are oriented transversely with respect to the valve holding bore in the valve carrier, wherein the outlet duct opens out, at a distance from the discharge of the filter element, in a portion of the valve holding bore in which the filter element has a closed sleeve portion, in order to achieve a noise reduction through targeted diversion of the flow in the direction of the outlet duct.
US11458941B2 Method for decelerating a trailer vehicle, wheel module for performing the method and vehicle combination having a wheel module of this type
A method for decelerating a trailer vehicle in a vehicle combination having a tractor vehicle and at least one trailer vehicle includes determining, by a wheel module at a respective wheel of the trailer vehicle, acceleration measurement values of the respective wheel, generating, by the wheel module, an information signal taking into account the acceleration measurement values of the respective wheel, and transmitting the information signal in a wireless fashion. The method further includes evaluating the acceleration measurement values and monitoring the acceleration measurement values with respect to a locking tendency of the respective wheel, and when an information signal of the wheel module is received, adjusting, by an electronic brake control unit, the trailer brake pressure taking into account the information signal.
US11458936B2 Drive assist apparatus
A drive assist apparatus includes a detector and a traveling controller. The detector detects an operation target of automatic emergency braking of a vehicle. The traveling controller includes a calculator and a determiner, and controls the automatic emergency braking on the basis of a result of the detection performed by the detector. The calculator calculates each of a target deceleration rate and a variation rate. The target deceleration rate is a target value of a deceleration rate of the automatic emergency braking. The variation rate is a rate of variation in the deceleration rate required for the deceleration rate of the automatic emergency braking to reach the target deceleration rate. The determiner determines a contact risk of the vehicle with the operation target on the basis of the target deceleration rate. The calculator increases the variation rate when the contact risk is determined by the determiner as being relatively high.
US11458931B2 Wiper drive circuit
When a power failure does not occur, power supply to a first terminal of a wiper motor is performed by a first battery, and power supply to a second terminal of the wiper motor is performed by a second battery. When a power failure occurs in one of the first battery or the second battery, power supply to the wiper motor is performed by the other battery that is not in power failure.
US11458928B2 Vehicle control apparatus
A vehicle control apparatus is mounted on a vehicle to perform wireless communication with a portable terminal. The vehicle control apparatus includes a first processor and a second processor. The first processor execute a first process to determine whether or not a wireless signal is a regular wireless signal transmitted from the portable terminal. The second processor executes a second process including an authentication of the portable terminal in response to the received wireless signal being determined to be the regular wireless signal, and does not execute the second process in response to the received wireless signal being determined to be not the regular wireless signal. Herein, a power consumption when the first processor executes the first process is smaller than a power consumption when the second processor executes the second process.
US11458921B2 Instrument panel
An instrument panel mounted on a vehicle and covering an airbag may include: a panel body including a first slit at a position opposing the airbag; a decorative sheet constituted of at least one of cloth and leather, the decorative sheet covering an area of the panel body including the first slit, and the decorative sheet including at least one second slit arranged along the first slit; and a fastener fastening the decorative sheet on the panel body. The fastener may include: a cover plate covering the at least one second slit; and at least one anchor extending from a back surface of the cover plate and passing through the first slit and the at least one second slit, the at least one anchor being fixed to the panel body.
US11458916B2 Side protection device for vehicle
A side protection device fora vehicle according to an embodiment of the present invention may comprise: a main body housing detachably attached to a side of a vehicle; a guard unit rotatably installed in the main body housing, deployed along the full-length direction of the vehicle for protecting the side of the vehicle from an external physical impact; and a fixing unit installed in the main body housing for catching and fixing the main body housing from the side of the vehicle by a manual operation.
US11458914B2 Method of onboard AC power generation for vehicles with combustion engine
An AC inverter in a vehicle operates using a 24 V input when a vehicle powertrain is in a parked/idling state. A first 12 V battery is connected with a first bus segment. A second 12 V battery is connected with a second bus segment. A switch module selectably interconnects the first and second bus segments. In a nominal 12 V state, the batteries are connected in parallel from the bus segments to ground. In a dual voltage state, the batteries are connected in series so the first bus segment is at 12 V and the second bus segment is at 24 V. A first alternator driven by the powertrain provides a regulated voltage to the second bus segment, wherein the regulated voltage corresponds to 12 V when the switch module is in the nominal state and corresponds to 24 V when the switch module is in the dual voltage state.
US11458911B2 OS monitor
An in-vehicle communication network comprising a bus and at least one node connected to the bus; an in-vehicle network operating system (OS) that manages OS processes, to enable a processor to run the processes and execute their respective process codes; and a module hosted in the OS that is configured to monitor the OS and vet a process that the OS enables for running by a processor to determine if the process is potentially damaging.
US11458910B2 Wire harness unit
A wire harness unit includes a first electrical cable, a first tubular member that covers the first electrical cable, a rubber member that is attached to an outer circumferential surface of the first tubular member, a bracket that includes a first fixing portion supporting the first tubular member with the rubber member in between, and a fastening member that surrounds and fastens the rubber member and the first fixing portion. The first tubular member is made of a metal that contains a first metal as a major component. The bracket is made of a metal that contains a second metal, which is different from the first metal, as a major component.
US11458909B2 Adapter clip
An adapter clip includes a first portion configured to fit within an engine clip or an engine clamp, a second portion including an annular portion, the annular portion being configured to fit around an engine component, and a web portion connected to the annular portion and the first portion. A diameter of the first portion differs from a diameter of the annular portion.
US11458903B2 Vehicle storage assembly
A storage assembly for a vehicle includes retention features that are operable between a first position and a second position. A receiving portion defines a first opening and a second opening. A support body is coupled to the receiving portion via at least one coupling member, and a retention member is operably coupled to the support body and is selectively coupled to the retention features.
US11458901B2 Fibrous front storage compartment for a vehicle
A moulded front storage compartment for a vehicle, comprising a structural layer wherein the structural layer is shaped as a three-dimensional storage cavity for holding luggage or goods wherein the structural layer comprises at least one porous fibrous layer and wherein the at least one porous fibrous layer comprises staple fibers and a binder.
US11458898B2 Overhead console
An overhead console includes a console housing, an illumination board, a vehicle interior checking mirror, a mirror surface light source mounted on the illumination board together with the illumination light source and configured to emit light toward the mirror surface of the vehicle interior checking mirror in the mirror surface visible position, and a see-through display plate that is a display plate capable of transparently displaying a symbol indicating predetermined information, the see-through display plate being provided in the console housing at a location between the mirror surface light source and the mirror surface so as not to hinder the passenger from visually recognizing the mirror surface and so as to face a partial region of the mirror surface, and the see-through display plate being configured to allow light from the mirror surface light source to transmit therethrough to display the symbol on the partial region of the mirror surface.
US11458894B2 Structure and method for mounting flag-type side mirror
A structure and method for mounting a flag-type side mirror securely fastens the flag-type side mirror on a door panel of a vehicle. The structure includes: a mirror neck (11) of the flag-type side mirror which is fastened to the door (20) formed with a plurality of panels bonded to each other, where the mirror neck (11) has an end fastened to one panel of the plurality of panels of the door (20), and a portion of the panel to which the mirror neck (11) is fastened is circumferentially bonded to another panel of the plurality of panels of the door (20).
US11458887B2 Reflective lamp assembly for a vehicle
A vehicle includes a lift gate that is operable between a closed position and an open position, and a lamp assembly. The lamp assembly includes a housing coupled to the lift gate and having a backing with a reflective surface, a light source that is coupled to the housing and configured to emit light, and a lid that is operably coupled to the housing. The lid includes a reflective interior surface and reflective exterior surface that is opposite the reflective interior surface. The lid is operable between an open position, wherein the reflective surface of the backing is exposed, and a closed position.
US11458886B2 System and method for the detection of a second vehicle in a detection zone of a first vehicle
A detection system designed to be mounted in a first vehicle. The detection system has a detection device configured to detect the presence of a second vehicle in a detection zone of the first vehicle, an alert device configured to generate a first stimulus perceptible by the driver of the first vehicle if a second vehicle is present in the detection zone, and a monitoring device configured to detect a reaction by the driver of the first vehicle in response to the first stimulus. The alert device is configured to generate a second stimulus in case of reaction by the driver of the first vehicle in reaction to the first stimulus.
US11458883B2 Adjustment device for a motor vehicle headlight
Adjusting device for adjusting an optically relevant assembly of a motor vehicle headlight. The device includes: a drive device with a first actuator adjustable along a displacement axis and having a first engaging portion, a transfer element mechanically engaged with the first actuator, and which has a first counter engaging portion corresponding to the first engaging portion, a supporting bushing in which the transfer element is supported and rotatable about the displacement axis, wherein the supporting bushing is firmly connected to a carrying frame, wherein the assembly is arranged on the carrying frame, and a second actuator rotatable about the displacement axis and having a second engaging portion, wherein the transfer element has a second counter engaging portion arranged opposite to the first counter engaging portion on the displacement axis, and wherein the second counter engaging portion is mechanically engaged with the second engaging portion.
US11458882B1 Load securing device
A load securing device for securing a load in a container. In an example embodiment, the load securing device includes a first support, a second support telescopic connected to the first support and a locking mechanism connected between the first support and the second support. In an adjustment mode, the locking mechanism moves the first support away from the second support until the first support touches a wall of the container and the second support touches the load. In a locked mode, the locking mechanism applies the force against the wall and against the load to secure the load. Another example implementation includes a second adjustment mechanism.
US11458881B2 System and method to anchor a position detector of a vehicle to a support plane
An anchoring system designed to anchor a position detector on a support plane in a predetermined lateral position relative to a vehicle. The anchoring system comprises a positioning plate, which is firmly fixed on the support plane in the predetermined lateral position, a flat base, which is firmly fixed to the position detector and is designed, in use, to be laid on the positioning plate, magnetic devices, which are arranged on the flat base and on the positioning plate and are structured so as to magnetically attract one another so as to firmly anchor, though in a removable manner, the base of the position detector on the positioning plate.
US11458878B2 System and method for determining carryback in surface haulage
A system for removing carryback material from the interior surface of a dump body. A controller is configured to determine a pose of the dump body, determine the current profile of the dump body, and determine the pose of the perception sensor. The controller is further configured to determine a difference between the current profile and the reference profile, determine whether the difference between the current profile and the reference profile exceeds the carryback threshold. Upon the difference between the current profile to the reference profile exceeding a carryback threshold, the dump body is designated for a clean out operation. The controller is further configured to generate movement command signals to perform a clean out operation on the dump body to remove an amount of material from the interior surface so that the difference between the current profile to the reference profile is less than the carryback threshold.
US11458877B2 Materials transport vehicle
A vehicle on which a container (1) is mounted for transporting materials, said container comprising a movable partition (10) extending transversely inside the container. The vehicle comprises a motor (16) pulling on a pair of cables (14a, 14b), the front ends of which are connected to the partition (10) on either side, in order to pull the partition (10) towards the rear of the container so as to unload the materials. The cables run along the side walls (4a, 4b) of the container, at a distance from a bottom of the container. The side walls (4a, 4b) of the container have projections (24a, 24b) each extending towards the inside of the container and overhanging the cables so that said cables are protected from falling materials during loading of the container from above.
US11458874B2 Vehicle seat
A vehicle seat includes a lock-to-neutral-position mechanism that locks a seat cushion at a neutral position, and an immediate lock mechanism that locks the seat cushion immediately at a current position when locking is required. A steering sensor senses a steering angle and a steering angular velocity. The immediate lock mechanism performs the locking when the steering angle is large, whereas the lock-to-neutral-position mechanism performs the locking when the steering velocity is high. When the steering wheel is at the neutral position, the locking by the immediate lock mechanism is released and the locking is switched over to the lock-to-neutral-position mechanism that is in a lock ready state.
US11458873B2 Method for determining a fluid pressure
A method for determining a fluid pressure in a pneumatic bladder of a pneumatic adjusting device of a vehicle seat is disclosed, wherein the pneumatic bladder is connected to a valve for the filling or emptying of the bladder with or of fluid. Fluid start pressure at the valve is provided as initial pressure for determining of the fluid pressure in the bladder. Fluid throughflow through the valve device is determined using a first assignment rule which assigns the fluid throughflow to the fluid start pressure at the valve. The fluid throughflow obtained using the first assignment rule over a predetermined period of time is summed to determine a fluid quantity that has flowed through the valve. Fluid pressure present in the bladder is determined using a second assignment rule which assigns the fluid pressure present in the bladder to the determined fluid quantity.
US11458871B2 Seat cover
Seat covers for a seat with a headrest are disclosed. The design includes a seat cover for a seat having a headrest, including a backrest cover sized to at least partially cover a backrest of the seat, an opening disposed on the backrest cover sized to allow the headrest to pass therethrough, and a flap sized to cover the opening and that is transitionable between a closed position and an open position. The opening is sized similar to the flap and the backrest cover has a securable slit provided therein. The flap in the open position and the slit in an unsecured orientation enables the seat cover to fit over the headrest, and the flap can be closed under the headrest and the securable slit secured to form a closed orientation.
US11458870B2 Seat with air vent
It is an object to provide a seat of which a seating comfort can be improved. The seat includes a seat cushion pad having an air passage formed inside and an air vent formed at an upper surface thereof, and is configured to allow air in the air passage to blow out through the air vent, wherein the seat cushion pad includes a pad body and a cover member which is disposed over the pad body to form the air passage between the pad body and the cover member and in which the air vent is formed, and a front end portion of the cover member extends downward over a front end portion of the pad body.
US11458865B2 Seat track mechanism
A seat track mechanism for a vehicle seat. The seat track mechanism may include an upper track, a lower track, a striker, a lever, and a pawl. The lever may be rotatable about a lever axis. The pawl may be rotatable with respect to the lever about a pawl axis when the striker engages the pawl.
US11458863B2 Vehicle
A vehicle includes a high-voltage system circuit including a high-voltage battery, a low-voltage system circuit including an updater and a low-voltage battery having a lower output voltage than the high-voltage battery, a DC-DC converter coupled between the two circuits, a controller that controls the two circuits and the DC-DC converter, and a wireless communication device. The updater updates a program of an update-target device. The wireless communication device wirelessly receives update data for the program. The controller calculates time taken for updating the program, based on information on the update data. The controller causes the DC-DC converter to reduce in voltage output electric power of the high-voltage battery and then supply the electric power to the low-voltage system circuit, and thus charges the low-voltage battery in accordance with the calculated time. The updater updates the program using output electric power of the charged low-voltage battery.
US11458856B2 Combined BMS, charger, and DC-DC in electric vehicles
A controller of an electric vehicle is disclosed. The controller includes: a BMS LV module configured to manage a low voltage battery; a BMS HV module configured to manage a high voltage battery; a DC-DC module configured to control a plurality of DC-DC FETs; and an ampSwitch module configured to detect a short on a bus and switch to an open state, and further configured to command the DC-DC module or an alternator to match the low battery's voltage and switch to a closed state when voltage returns to normal.
US11458853B2 Methods and apparatus for powering a vehicle
This application is directed to an apparatus for providing electrical charge to a vehicle. The apparatus comprises a driven mass, a generator, a charger, a hardware controller, and a communication circuit. The driven mass rotates in response to a kinetic energy of the vehicle and is coupled to a shaft such that rotation of the driven mass causes the shaft to rotate. The driven mass exists in one of (1) an extended position and (2) a retracted position. The generator generates an electrical output based on a mechanical input coupled to the shaft such that rotation of the shaft causes the mechanical input to rotate. The charger is electrically coupled to the generator and: receives the electrical output, generates a charge output based on the electrical output, and conveys the charge output to the vehicle. The controller controls whether the driven mass is in the extended position or the retracted position in response to a signal received from the communication circuit.
US11458846B2 Brake control apparatus for vehicle
A brake force control apparatus allocates all of required brake force to a target front wheel friction brake force when the required brake force is equal to or smaller than a maximum regeneration brake force. The apparatus decreases the target regeneration brake force by a first predetermined amount at a first time point at which a front wheel acceleration varies from a value larger than a first acceleration threshold to a value equal to or smaller than the first acceleration threshold. The apparatus increases the target regeneration brake force in such a manner that the target regeneration brake force coincides with the required brake force, if the front wheel acceleration becomes larger than a second acceleration threshold in a period from the first time point to a second time point at which a predetermined time elapses from the first time point.
US11458843B2 Operating unit for a device, in particular for a vehicle component
The operating unit for a vehicle, in particular for a vehicle component, is provided with a housing (10) which has an operating element (12), such as a display for example, and is designed to be secured in a device, in particular in a vehicle dashboard. The operating element (12) is elastically mounted on the housing (10). An actuator (16) is additionally provided for mechanically exciting the operating element (12) when an operation of the operating element (12) has been detected. Finally, the operating unit also has a vibration compensating mass (20) which can be mechanically excited by the actuator or by one actuator (16) when an operation of the operating element (12) has been detected and/or which is mounted on the housing (10) and can be moved in order to substantially compensate for forces acting on the housing (10) when the operating element (12) is moved.
US11458839B2 Device and method for preventing driving under influence
A device and a method for preventing driving under influence, may include a first measuring device configured for detecting alcohol in indoor air of a vehicle, and a processor connected to the first measuring device, wherein the processor performs a first check of checking a presence or an absence of the alcohol in the indoor air through the first measuring device before a driver boards the vehicle, performs a second check of checking the presence or the absence of the alcohol in the indoor air through the first measuring device after the driver boards the vehicle, and determines whether there is a possibility that the driver is drunken based on the results of performing the first check and the second check.
US11458837B2 Drive train for an agricultural machine
A drive-train of an agricultural machine, such as a tractor, has a power-split transmission (1) and a separate transfer case (2). The transfer case (2) can be connected to a drive motor and the gear ratio of the transfer case (2) can be adapted in such manner that the power-split transmission (1) can be used for various drive powers.
US11458835B2 Cover apparatus for a motor vehicle body
A cover apparatus for a motor vehicle body has a movement device (5) with first and second guide rails (8, 9) that are spaced from one another and received rigidly on the motor vehicle body (2). A covering element (4) covers a filling connector (7) of the motor vehicle body (2) and is received movably on the motor vehicle body (2). The covering element (4) is coupled to the first and second guide rails (8, 9). A third guide rail (10) is transverse to the first and second guide rails (8, 9). The third guide rail (10) is configured to be movable relative to the motor vehicle body (2) and the first and second guide rails (8, 9). The third guide rail (10) is configured to receive the covering element (4), and the covering element can be moved relative to the third guide rail.
US11458834B2 Fluid control valve and evaporated fuel processing device
A fluid control valve is made compact by changing the shape of a communication passage within the fluid control valve. The fluid control valve includes a valve casing, an electric valve disposed in the valve casing, and a relief valve disposed in the valve casing. The valve casing includes: a main passage that has a first valve port sealed by the electric valve; a bypass passage for bypassing the first valve port; a first valve chamber in fluid communication with the downstream side of the first valve port and housing the electric valve; and a second valve chamber in fluid communication with the upstream side of the first valve port and housing the relief valve. The bypass passage includes a communication passage configured to allow the first valve chamber and the second valve chamber to fluidly communicate with each other. The communication passage opens to a first side surface of the first valve chamber and/or into a side surface of the second valve chamber.
US11458832B2 Motorcycle engine cooling system
A cooling system of an internal combustion engine of a motorcycle, which has a suction side guard (4), enables a high ratio between the open surface of the guard and its overall surface, ensuring an improved penetration of the air through the radiator and thus avoiding oversizing of the suction fan, wherein: said guard (4), having a lower edge (6), an upper edge (7), a front edge (8) and a rear edge (9) with respect to a running direction (F) of the vehicle, has a grate mesh structure extending on a plane whereby a deviation space (12) of motion of the air sucked by the fan is defined behind the guard (4); said grate mesh structure being surrounded by a rib (13) having, at the front edge (8), a lower height than that at the rear edge (9).
US11458830B2 Powertrain system
A powertrain system includes an internal combustion engine, a motor generator and a control device. The motor generator includes a rotating shaft connected to a crankshaft of the internal combustion engine via a torsional damper. The powertrain system is configured such that the crankshaft and the above-described rotating shaft are not connected to a drive shaft of a vehicle at least at the time of engine start. The control device is configured to execute a cranking torque amplification control that controls the motor generator such that the MG torque output from the motor generator for cranking the internal combustion engine fluctuates in a resonant period of the torsional damper while making a fluctuation center of the MG torque higher than zero.
US11458825B2 Battery and seat assembly for a hybrid motor vehicle
An assembly for a hybrid motor vehicle, in particular a partially electrified hybrid motor vehicle, having a vehicle battery and a vehicle seat comprising a seat surface. The vehicle seat is connected or connectable to a vehicle floor of the hybrid motor vehicle by means of a substructure having at least two seat rails. The vehicle battery is arranged or arrangeable beneath the vehicle seat and above the vehicle floor. The vehicle battery is held on the vehicle seat by means of a suspension means attached to the top side, or in an upper region, of the vehicle battery.
US11458814B2 Rotary operating element for operating a ventilation nozzle in an automobile passenger compartment
A rotary operating element for operating a ventilation nozzle in an automobile passenger compartment. The rotary operating element includes a first rotation body and a second rotation body, which are held against one another in a form-locked manner by tensioning elements. The tensioning elements are disposed spaced radially apart from a rotary operating element longitudinal axis and, starting at a particular torque threshold value, the form fit between the first and second rotation bodies is released, whereby the ventilation nozzle to be operated is protected against damage and/or faulty operation.
US11458804B2 Air conditioner cut control system and method thereof
An air conditioner cut control system may include a driving condition detection unit detecting operation conditions of a vehicle, an air conditioner controller configured of determining an intake manifold negative pressure stored in a brake booster at a value obtained by subtracting intake manifold pressure from an atmospheric pressure detected by the driving condition detection unit when the air conditioner is operated and an engine control unit (ECU) for integrating the intake manifold negative pressure according to a brake negative pressure prediction logic and determining a virtual brake booster sensor value by modeling change of booster negative pressure according to driving information, and the ECU, and if the virtual brake booster sensor value is below a reference negative pressure of an A/C CUT standard logic, the ECU determines that brake negative pressure is insufficient and activates A/C CUT.
US11458802B2 Optimized power management for a transport climate control energy source
An optimized power converter for use in a transport electrical system that provides power to a transport climate control system is provided. The optimized power converter includes an optimized DC/DC converter and an inverter/active rectifier. The optimized DC/DC converter is only boosts a voltage level when current is directed from a rechargeable energy storage to the inverter/active rectifier and only bucks a voltage level when current is directed from the inverter/active rectifier to the rechargeable energy storage. In a charging mode, the inverter/active rectifier converts three phase AC power into DC power, and the optimized power converter bucks the DC power to a voltage level that is acceptable for charging the rechargeable energy storage. In a discharge mode, the optimized DC/DC converter boosts voltage from the rechargeable energy storage, and the inverter/active rectifier converts boosted DC power into three phase AC power for powering a transport climate control system load.
US11458799B2 Vehicle thermal management systems and methods
An electric vehicle has a thermal management system that comprises a common radiator, a brake resistor loop, and an electric power source loop. The brake resistor loop comprises a brake resistor and a brake resistor controller that are coupled to the common radiator. The electric power source loop comprises an electric power source coupled to the common radiator. When the brake resistor loop is determined to be in operation, the common radiator is utilized by the brake resistor loop to absorb heat generated by the brake resistor loop. When the brake resistor loop is determined to not be in operation, the common radiator is utilized by the electric power source to absorb heat generated by the electric power source loop.
US11458798B2 Thermal management system for vehicle
The present invention relates to a thermal management system for a vehicle, which can provide various effects, such as a reduction of weight, a cost reduction, and a reduction of a package size due to a reduction in the number of components. The thermal management system for a vehicle, which includes a refrigerant circulation loop circulating refrigerant and exchanging heat between the refrigerant and inside air of an air-conditioning case in order to perform air-conditioning inside the vehicle, includes: a first coolant loop for cooling electric parts of the vehicle; and a second coolant loop for cooling a battery of the vehicle, wherein the first coolant loop and the second coolant loop are configured independently, and coolant flowing in the first coolant loop selectively circulates in the second coolant loop.
US11458793B2 Vehicle height adjustment device
A vehicle height adjustment device of the present invention includes a motion conversion unit that includes a rotating member and a linear motion member, and that converts a rotational motion of the rotating member into a linear motion of the linear motion member, a plurality of motors, a driven gear coupled to the rotating member, a plurality of drive gears that meshes with the driven gear, and a spring seat that is coupled to the linear motion member, and that supports one end of a suspension spring interposed between a vehicle body and an axle of a vehicle, wherein after driving the spring seat and then stopping the spring seat, some drive gears of the drive gears are driven in a direction opposite a drive direction of the spring seat.
US11458792B2 Methods and apparatus for center pivot suspension system
A center pivot suspension system according to various aspects of the present technology may include a multi-piece axle having controls arms that are pivotally connected to a center beam section of the axle. Each control arm may be able to pivot about the center section independently from the opposing control arm. A leaf spring may be coupled to each control arm to help absorb loads applied to a given control arm.
US11458791B2 Spring assembly for a vehicle bogie suspension arrangement
A spring assembly for a vehicle bogie suspension arrangement. The spring assembly includes a set of washers moulded into an elastomer body. The spring assembly has an axial extension in an axial direction and the washers are arranged relative to each other in the axial direction. At least one of the washers is a spring washer including a spring washer body and at least two spring tongues. Each spring tongue has a spring base connected to the spring washer body and a spring tip distal to the spring base. At least a portion of the spring tongue is located at a non-zero distance from the spring base in the axial direction.
US11458781B1 System for vehicle monitoring utilizing tire pressure sensors
A system for monitoring of a vehicle with an inflation signaling apparatus having at least one inflation reporting assembly. The inflation reporting assembly may be configured to wirelessly transmit an information signal including an identification (ID) code. The system may also include at least one vehicle monitoring apparatus configured to monitor a characteristic of the vehicle based upon the inflation signaling apparatus associated with the vehicle. The vehicle monitoring apparatus may be configured to sense a presence of the inflation reporting assembly proximate to the vehicle monitoring apparatus via reception by the monitoring apparatus of a transmission of the ID code by the inflation signaling apparatus associated with the vehicle.
US11458773B2 Tyre for running on rough terrain
A tyre for running on rough terrain includes a tread portion. The tread portion includes a crown region, middle regions, and shoulder regions. The crown region is provided with a plurality of crown blocks. The middle regions are provided with a plurality of middle blocks. The shoulder regions are provided with a plurality of shoulder blocks. Each of the middle blocks is connected with at least one of the crown blocks by a crown tie bar and connected with at least one of the shoulder blocks by a shoulder tie bar. A land ratio of the shoulder regions is 90% or more and 115% or less of a land ratio of the crown region.
US11458772B2 Two-layer multi-strand cords having very low, low and medium moduli
A two-layer multi-strand cord (60) comprises an internal layer (CI) of the cord made up of J>1 internal strands (TI) and an external layer (CE) of the cord made up of L>1 external strands (TE). The cord satisfies the relationship 95≤MC≤175, where MC=(J×MI+L×ME)/(J+L); MI=200×cos4(α)×[Q×(D1/2)2×cos4(β)+N×(D2/2)2×cos4(γ)]/[Q×(D1/2)2+N×(D2/2)2]; and ME=200×cos4(α′)×[Q′×(D1′/2)2×cos4(β′)+P′×(D2′/2)2×cos4(δ′)+N′×(D3′/2)2×cos4(β′)]/[Q′×(D1′/2)2+P′×(D2/2)2+N′×(D3′/2)2], where D1, D1′, D2, D2′, and D3′ are in mm, α and α′ are the helix angle of each internal and external strand (TI), β and β′ are the helix angle of each internal thread (F1, F1′), δ′ is the helix angle of each intermediate thread (F2′) and γ and γ′ are the helix angle of each external thread (F2, F3′).
US11458771B2 Wheels having shock absorbing characteristics and a surface treatment apparatus using the same
A vacuum cleaner can include an upright section, a surface cleaning head coupled to the upright section, and at least one wheel coupled to the surface cleaning head. The at least one wheel can include a hub, a rim, and an absorber. The absorber can extend between the hub and the rim. The absorber can be configured to deform before the rim experiences substantial deformation. A deformation limiter can be provided that is configured to limit the deformation in the absorber.
US11458769B2 Pneumatic tire
Provided is a pneumatic tire having at least one carcass layer as a skeleton extending in toroidal shape over a pair of bead portions, at least one belt layer and a tread disposed on an outer side in the radial direction of a crown portion of the carcass. In a tire section in the widthwise direction in state where the tire is assembled to an application rim, ratio BD/BW of radius difference BD between radius at a center portion and radius at an end portion in the widthwise direction of an innermost layer of the belt layer, to width BW of the innermost layer, ranges from 0.01 to 0.04, and ratio TD/TW of radius difference TD between radius at a center portion and radius at an end portion of the tread in the widthwise direction of a tread ground surface, to tread ground-contact width TW, satisfies BD/BW
US11458767B2 Pneumatic tire and crosslinked rubber composition
A pneumatic tire includes bead cores, a carcass ply, an inner liner and the tread, and the crosslinked rubber composition, of the present invention, wherein the tread and the crosslinked rubber composition have a volume of the low density region of 35% or more at elongation by an applied stress of 1.5 MPa, a volume of the void portion of 7.5 or less at elongation by an applied stress of 3.0 MPa and a ratio of 40% by mass or more of a component having a weight-average molecular weight of not less than 1,000,000 in a molecular weight distribution measured by gel permeation chromatography are excellent in abrasion resistance.
US11458757B2 Lithographic printing plate precursor and method of producing lithographic printing plate
A lithographic printing plate precursor includes an image recording layer on a support, in which the lithographic printing plate precursor has projections which are discontinuously formed on a surface of an outermost layer on a side where the image recording layer is provided, and a melting point of each projection is in a range of 70° C. to 150° C.A method of producing a lithographic printing plate includes a step of image-wise exposing the lithographic printing plate precursor to form an exposed portion and an unexposed portion, and a step of supplying at least one of printing ink or dampening water to remove the unexposed portion.
US11458755B2 Printing process for transferring a printing substance
The present invention relates to a printing method for transferring printing substance from an ink carrier to a substrate, in which the printing substance undergoes a change in volume and/or position with the aid of an energy-emitting device that emits energy during a process time in the form of electromagnetic waves wherein the printing substance comprises a high molecular weight binder. In addition, the present invention describes a printing substance for carrying out the method and the use thereof.
US11458752B2 Printer
A printer includes head that performs printing by ejecting ink at a position of ejection of the ink in a print coordinate system, camera that captures an image of an area where the ink is ejected and outputs the image in an image coordinate system, camera capturing an image of calibration pattern printed by ejecting the ink at a calibration ejection position and outputting the image including calibration pattern, the calibration ejection position being a position at which calibration pattern is printed by ejecting the ink, and calculator that calculates the amount of displacement between the position of calibration pattern in the image coordinate system and the calibration ejection position in the print coordinate system.
US11458750B2 Accommodation body and tape printing system
Disclosed is an accommodation body including: a tape roll accommodation part in which a tape roll on which a tape to be fed to a tape printing apparatus is wound is accommodated; a wall part that is provided with a tape discharge port from which the tape fed from the tape roll is to be discharged; and a cartridge accommodation part in which a ribbon cartridge that has an ink ribbon and is to be installed in the tape printing apparatus while retaining the tape fed from the tape roll is accommodated.
US11458738B2 Image forming apparatus and image forming method
An image forming apparatus includes: a hardware processor that forms an image on a conveyed recording medium; and a determining device that determines whether a type of the recording medium is a first recording medium or a second recording medium, wherein if the type of the recording medium is determined to be the first recording medium, the hardware processor forms a normal image on the recording medium, whereas if the type of the recording medium is determined to be the second recording medium, the hardware processor forms a test image on the recording medium.
US11458735B2 Liquid discharge apparatus
A liquid discharge apparatus includes: a casing having: a first surface and a second surface positioned apart in a first direction; a third surface and a fourth surface positioned apart in a second direction; and a fifth surface and a sixth surface positioned apart in a third direction; a head; a tank storing a liquid to be supplied to the head; and a sheet accommodating portion accommodating a sheet. The tank is positioned between the first surface and the sheet accommodating portion in the first direction. A range occupied by the tank at least partially overlaps with a range occupied by the sheet accommodating portion in the second direction. A range occupied by the tank at least partially overlaps with a range occupied by the sheet accommodating portion in the third direction.
US11458733B2 Recording apparatus
A printer includes a line head, a transport unit, a head moving unit, a maintenance unit, a lid unit, and a rotation mechanism portion. The head moving unit moves the line head to a retreat position and a recording position along a B direction. The maintenance unit includes a cap portion configured to cover the nozzles, is formed with an opening, and is movable in a transport direction of a medium. A lid unit is rotatable about a rotation axis, and closes the opening in a closed posture. When the head moving unit moves the line head from the recording position to the retreat position, the rotation mechanism portion rotates the lid unit so that a posture of the lid unit becomes the closed posture.
US11458731B2 Image forming apparatus
An image forming apparatus includes an ink having a dynamic surface tension of from 30 to 50 mN/m at a life time of 15 msec at 25 degrees C., a container containing the ink, and a head configured to discharge the ink to a fabric including a first fabric containing synthetic fiber in an amount of more than 50 percent by mass and a second fabric containing natural fiber in an amount of 50 percent by mass or greater, wherein the droplet of the ink discharged to the first fabric is larger than the droplet of the ink discharged to the second fabric.
US11458723B2 Support material formulation and additive manufacturing processes employing same
Novel support material formulations, characterized as providing a cured support material which is readily removable by contacting with water, are disclosed. The formulations comprise a curable water-soluble mono-functional monomer, a water-miscible polymer and a silicone polyether. Methods of fabricating a three-dimensional object, and a three-dimensional object fabricated thereby are also disclosed.
US11458720B2 Composite material bonding apparatus and composite material bonding method
The embodiment includes: a planar graphite heater; a clamp device that moves the graphite heater, which is arranged between a first bonding surface W1a of a first composite material member and a second bonding surface of a second composite material member facing the first bonding surface, in a traveling direction with the graphite heater being in contact with the first bonding surface and the second bonding surface; and a control unit that controls the graphite heater to heat the first bonding surface and the second bonding surface while the graphite heater is in contact with the first bonding surface and the second bonding surface.
US11458716B2 Lamination apparatus and method of manufacturing display device using the same
A lamination apparatus including a first stage including a first body portion and an accommodation portion disposed on a bottom surface of the first body portion, a second stage disposed to face the first stage, and a jig device disposed between the first stage and the second stage, the jig device including a second body portion and at least one jig portion, in which the at least one jig portion has one end fastened to the second body portion and the other end having a rounded shape.
US11458709B2 Three shot plastic tailgate
A plastic glazing of a tailgate of a vehicle is provided, the plastic glazing comprising a translucent component, wherein a portion of the translucent component forms a rear window of the vehicle, a colored component molded onto the translucent component in a second shot, wherein the colored component comprises a lens of a light unit, a non-transparent component molded onto the translucent component, wherein an overlapping portion of the translucent component and the non-transparent component forms a blackout region proximate to the rear window, wherein the plastic glazing is of one-piece molded plastic construction, wherein the translucent component comprises a first textured surface in a region adjacent to the blackout region, where the first textured surface is configured to conceal a component of the vehicle.
US11458708B2 Decorative sheet, decorative panel, and coating agent for forming surface protective layer
A decorative sheet having a surface-protecting layer, the surface-protecting layer having excellent contamination resistance, alkali resistance, etc., for a long period of time, while limiting the occurrence of breakage and cracks when an impact is applied thereto or during processing; and a decorative plate using the decorative sheet is provided. Specifically, a decorative sheet comprising a laminate, the laminate comprising at least a base material sheet and a first surface-protecting layer in sequence in the thickness direction; (1) the first surface-protecting layer comprising an ionizing radiation-curable resin containing two kinds of aliphatic urethane acrylates, i.e., resin A and resin B, wherein resin A is an aliphatic urethane acrylate with an isocyanurate skeleton, and resin B is an aliphatic urethane acrylate with an alicyclic skeleton without an isocyanurate skeleton, and (2) the first surface-protecting layer having a nanoindentation hardness of 160 MPa or more and 240 MPa or less.
US11458704B2 Carrier film for transferring microelement
The present invention relates to a carrier film for transferring a microelement, wherein, when a microelement is pressurized, a uniform pressurizing force is provided to the entire microelement, and a damage to the microelement can be prevented. The carrier film for transferring a microelement comprises: a load control layer having a first elastic modulus and having a space formed in a part of the interior thereof; and an adhesive layer having a second elastic modulus that is smaller than the first elastic modulus, the adhesive layer being provided on the upper portion of the load control layer and configured such that a microelement supposed to be transferred to a target substrate is attached thereto. The load control layer has a first zero-rigidity area that maintains a first stress in a first deformation range from a first strain to a second strain.
US11458701B2 Device and method for pressing organic material out of waste
A press for processing organic waste has two plungers. Preferably, the plungers have rectangular cross sections. The two plungers are mounted in the press such that they are perpendicular to each other and have partially overlapping stokes. The press has walls that partially enclose a pressing chamber. The pressing chamber is as wide as one plunger on one side, and as wide as the other plunger on another side. In operation, one of the two plungers is used to optionally load organic waste into the pressing chamber, to partially enclose the pressing chamber while the waste is compressed, and to eject compressed waste from the pressing chamber. The other plunger is used to compress waste in the pressing chamber whereby a pressate is produced through perforations in a wall of the pressing chamber. The other plunger may also partially enclose the pressing chamber while compressed waste is ejected.
US11458700B2 Mold apparatus, mold system, and method for molding sole component of article of footwear
Mold systems for molding fluid-filled elements include a lower mold body having a lower mold surface and an upper mold body having an upper mold surface. A mold apparatus is disposed between the lower and upper mold bodies. This mold apparatus includes: (i) a first arm providing a first mold surface extending between first and second ends of the first arm, and (ii) a second arm providing a second mold surface extending between first and second ends of the second arm. The first and second mold surfaces have surface contours configured to form molded undercut surface features of the fluid-filled element. Methods of molding fluid-filled elements using such mold systems also are described.
US11458697B2 Method for polishing polyamide objects obtained by additive manufacturing or 3D printing techniques
The present invention refers to a method for polishing polyamide objects obtained by additive manufacturing or 3D printing techniques, which comprises immersion of the polyamide object in a mixture of formic acid and dichloromethane at room temperature for a period of time comprised between 5 seconds and 6 minutes. This method allows effectively elimination or reduction of the roughness of the polyamide objects obtained by additive manufacturing or 3D printing techniques, for example, obtained by techniques such as the Selective Laser Sintering (SLS) with a simple procedure which does not require neither high temperatures nor extended treatment times. The present invention also refers to the object obtainable according to such method.
US11458690B2 Method and apparatus for bonding substrates
The present disclosure relates to methods for bonding first and second substrates together with tackifier free adhesives. The tackifier free adhesive may be applied to the second substrate to define an adherence zone. The first substrate is positioned on the adherence zone of the second substrate to define a first region and a second region of the adherence zone. In the first region, the tackifier free adhesive is positioned between the first substrate and the second substrate. In the second region, the tackifier free adhesive may or may not be positioned between the first substrate and the second substrate, and may not bond the first substrate with the second substrate. Thus, tackifier free adhesive may be applied to the second substrate to create an adherence zone defining a relatively large area that permits the placement of the first substrate thereon without the need to completely cover the adherence zone.
US11458686B2 Method for calibrating a device for producing a three-dimensional object and device configured for implementing said method
A calibration method serves for calibrating a manufacturing device for additively producing a three-dimensional object by applying layer by layer and selectively solidifying a building material. The manufacturing device comprises at least two scanning units, each of which is capable of directing a beam to different target points in the working plane, which are located within a scanning region assigned to the respective scanning unit, wherein the scanning regions region of the at least two scanning units overlap in an overlap area. At least a first of the at least two scanning units is assigned a first monitoring unit whose monitoring region extends to a target point of the first scanning unit and its proximity, wherein a change of a position of the monitoring region is carried out as a function of a change of a position of the target point.
US11458684B2 High-throughput and high-precision pharmaceutical additive manufacturing system
The present disclosure relates generally to manufacturing pharmaceutical products using additive manufacturing technology. An exemplary printing system comprises: a material supply module for receiving a set of printing materials; a flow distribution module comprising a flow distribution plate, wherein the material supply module is configured to transport a single flow corresponding to the set of printing materials to the flow distribution plate; wherein the flow distribution plate comprises a plurality of channels for dividing the single flow into a plurality of flows; a plurality of nozzles, wherein the plurality of nozzles comprises a plurality of needle-valve mechanisms; one or more controllers for controlling the plurality of needle-valve mechanisms to dispense the plurality of flows based on a plurality of nozzle-specific parameters; and a printing platform configured to receive the dispensed plurality of flows, wherein the printing platform is configured to move to form a batch of the pharmaceutical product.
US11458682B2 Compact build tank for an additive manufacturing apparatus
The invention relates to a build chamber (1) for an additive manufacturing apparatus (100) for forming a three-dimensional article layer by layer from a powder. The build chamber (1) comprising a build chamber base body (2) and the build chamber base body (2) is formed by at least two segments (4) telescopically coupled together. Associated with the telescopically coupled segments are one or more bellows assemblies, further coupled to support structure configured to raise and/or lower the build table. An associated method is also provided.
US11458680B2 Calibrating a head system of a power radiation source of an additive manufacturing device
A kit for the calibration of a head system of a power radiation source of an additive manufacturing device comprises: a calibration plate having a plurality of reference marks, and a firing support made from at least one material sensitive to the radiation of the source, this support leaving the reference marks of the calibration plate visible when it is in place thereon, characterized in that the firing support comprises a plurality of windows distributed in such a way as to become superposed with the various reference marks of the calibration plate and leave them visible when the firing support is in place on the calibration plate. There is also a method for calibrating such a system.
US11458676B2 Resin powder and method of manufacturing solid freeform fabrication object
A resin powder contains a resin contains columnar particles, wherein the proportion of the columnar particles having a ratio (L/W) of less than 1 is 50 percent by volume or more in the total volume of the resin powder, where W represents the width in the radial direction of the columnar particles and L represents the length in the axis direction of the columnar particles.
US11458674B2 Method and device for producing a workpiece
A device and production method, in which a workpiece is built up gradually in layers. To build up the workpiece, preformed layers, which are individually formed on a layer support using an electrophotographic printing process are transferred one at a time from the layer support to the workpiece. For this purpose, the layer is transferred to the workpiece in a printing operation, the layer being preferably laid on the workpiece by a die. In one embodiment, a plurality of workpieces are built up simultaneously and a plurality of preformed layers are transferred simultaneously to different respective workpieces. In another embodiment, the layer is formed on the layer support, which is preferably a film or paper, prior to being transferred.
US11458672B2 Method and device for building a shaped body by stereolithographic solidification of building material by photopolymerization
The present invention is directed to a method and a device for building a shaped body by stereolithographic solidification of building material by photopolymerization.
US11458669B2 Process of changing cross sectional shape within a textile
Methods, systems, and devices for changing cross-sectional sizes and/or shapes of flat braided sutures and the resulting constructs are disclosed. The flat braided sutures can have a textile first cross-sectional shape that can be changed to a textile second cross-sectional shape. The systems can have a heater and a die. The flat braided sutures can be movable through the heater and the die. When the flat braided sutures are in the heater, the flat braided sutures can be heatable from a textile first temperature to a textile second temperature greater than the textile first temperature. When the flat braided sutures are at the textile second temperature, the textile first cross-sectional shape can be changeable to the textile second cross-sectional shape.
US11458666B2 Method and apparatus for cooling
The present invention relates to a method and apparatus for cooling. An apparatus includes an annular cooling ring operable for receiving a flow of a molten film bubble and expelling a flow of cooling gas, the annular cooling ring comprising a middle lip and an adjacent radially spaced apart outer lip, the middle lip having an extended length longer than the outer lip, a radially inner surface of the outer lip and a radially outer surface of the middle lip define a channel operable to allow the flow of cooling gas along the radially outer surface of the middle lip, wherein the middle lip is located radially intermediate the channel and the molten film bubble, and wherein the middle lip isolates the molten film bubble from the flow of cooling gas until the flow of cooling gas passes beyond the extended length of the middle lip
US11458662B2 Method for producing plastic/metal hybrid components
A method produces plastic/metal hybrid components, in particular for the automotive field. A plastic compound is injected into a tool mold, and the tool mold has a core onto which a metal is injected. The plastic compound is then injected into the tool mold such that the metal is back-molded with the plastic compound and is fixed to the plastic in order to produce a blank. The tool mold is used to produce at least one depression in the surface of the blank, the depression being at least partly filled with a metal as part of a first additional processing.
US11458660B2 Method for manufacturing an enclosure assembly for a utility meter and same
A method for manufacturing an enclosure for a utility meter is provided, wherein at least two of a main cover part, an exterior terminal cover part, and an interior terminal cover part are at least partly formed jointly as a cover assembly in an injection moulding device. Further provided is a utility meter with an enclosure manufactured by the method.
US11458651B2 Pre-consolidation of thermoplastic fiber preforms and method of making the same
A process is provided for forming a pre-consolidated fiber preform for use in a molding process. The process includes layering a plurality of preform sheets on a pre-consolidation mold. Heating the plurality of preform sheets to a first temperature. Applying a first pressure to the plurality of preform sheets using the pre-consolidated mold. Maintaining the first temperature and the first pressure and heating for a first duration of time. A second pressure and a second temperature are then applied to the plurality of preform sheets for a second duration of time.
US11458646B2 Method and apparatus for removing wrapping from rolls
In a method for removing a wrapping, such as plastic film, from a roll of material an apparatus is used, which has a roll supporting unit, and a cutting means. The roll supporting unit is configured to rotate the roll supported thereon, and the cutting means is movable into cutting abutment against the envelope surface of the supported roll for removal of the wrapping during rotation of the roll.
US11458637B2 Control apparatus, control method, and medical support arm apparatus
[Object] To enable further suppression of the movement amount of an arm section when switching states.[Solution] There is provided a control apparatus configured to execute a current tracking control on a basis of a measurement value of a torque sensor of an actuator provided in at least one of multiple joint sections included in an arm section of a medical support arm apparatus, the current tracking control causing a motor of the actuator to output torque by which a position and an attitude of the arm section are maintained, and switch a first state in which the motor is driven in accordance with a predetermined control method, and a second state in which the joint section is locked using a brake of the actuator.
US11458635B2 Method and system for manipulating articles
Various example embodiments described herein relate to an item manipulation system including a control system and a robotic arm coupled to the control system. The item manipulation system includes an end effector communicatively coupled to the control system and defines a first end and a second end. The first end of the end effector is rotatably engaged to the robotic arm. The item manipulation system also includes a gripper unit attached to the second end of the end effector. The gripper unit is configured to grip the item. The gripper unit includes at least one flexible suction cup and at least one rigid gripper. Each of the flexible suction cup and the at least one rigid gripper engage a surface of the item based on vacuum suction force generated through the at least one flexible suction cup or the at least one rigid gripper.
US11458633B2 Article transfer apparatus
An article transfer apparatus includes a holding portion, a driving portion that moves the holding portion, a control unit, and a reference detection portion that detects a reference position of a target article held by the holding portion. The control unit performs reference detection control to detect, by the reference detection portion, the reference position in a state in which the target article is lifted, determination control to determine a positional relationship between the holding portion and the reference position based on a result of detection by the reference detection control, and position calculation control to calculate, based on the positional relationship determined by the determination control, a movement destination position that is a position, of the holding portion at the movement destination, at which an outer edge of the target article held by the holding portion fits within a movement region.
US11458632B2 Robot having reduced vibration generation in in arm portion
There is provided a robot capable of reducing vibration generated in an arm portion performing work. The robot includes: a first arm portion connected to a body portion and configured to perform work; and a second arm portion connected to the body portion and to be controlled to support the first arm portion, in which the first arm portion includes a first connecting portion connected to the body portion, a first end effector located at an end of the first arm portion opposite to an end where the first connecting portion is located, and a support target portion located between the first connecting portion and the first end effector, and the second arm portion is controlled to support the support target portion.
US11458631B2 Vehicle transport apparatus
A vehicle transport apparatus is formed by a first robot and a second robot that enter underneath a vehicle, lift up wheels of the vehicle, and travel. The first robot and the second robot each include a distance sensor that detects a distance between the corresponding robot and an object near the corresponding robot, and a robot computing section that controls a travel operation and a loading operation of the corresponding robot. When the vehicle is to be lowered in a parking region, the robot computing section adjusts a parking position of the vehicle based on information detected by the distance sensor.
US11458630B2 Mitigating reality gap through simulating compliant control and/or compliant contact in robotic simulator
Mitigating the reality gap through utilization of technique(s) that enable compliant robotic control and/or compliant robotic contact to be simulated effectively by a robotic simulator. The technique(s) can include, for example: (1) utilizing a compliant end effector model in simulated episodes of the robotic simulator; (2) using, during the simulated episodes, a soft constraint for a contact constraint of a simulated contact model of the robotic simulator; and/or (3) using proportional derivative (PD) control in generating joint control forces, for simulated joints of the simulated robot, during the simulated episodes. Implementations additionally or alternatively relate to determining parameter(s), for use in one or more of the techniques that enable effective simulation of compliant robotic control and/or compliant robotic contact.
US11458629B2 Robot system and method of operating the same
A robot system includes a transfer device, a plurality of robots, a sensor configured to detect a workpiece to which a work has not yet been performed, and a controller provided to each of the plurality of robots. The plurality of robots are disposed in series in a transferring direction of a workpiece. When the sensor detects the unworked workpiece and the robot is in a stand-by state, the controller causes the robot to perform the work to the unworked workpiece, and when the sensor detects the unworked workpiece and the robot is working, the controller inhibits the robot to perform the work to the unworked workpiece.
US11458628B1 Method for efficient operation of mobile robotic devices
A method for a robot to autonomously plan a navigational route and work duties in an environment of the robot including accessing historical sensor data stored from prior work cycles, determining the navigational route and work duties of the robot by processing probabilities based on the historical sensor data, enacting the navigational route and work duties by the robot, capturing new sensor data while the robot enacts the navigational route and work duties, processing the new sensor data, and altering the navigational route and work duties based on the new sensor data processed.
US11458627B2 Method and system of robot for human following
A system of a robot for human following includes the robot faced toward a first direction. The robot includes a detecting device, a controlling device and a mobile device. The detecting device detects a target human and a obstacle. The controlling device generates a first parameter according to a first vector between the target human and the robot, generates a second parameter according to a second vector between the obstacle and the robot, and generates a driving command according to a first resultant force parameter generated from the first parameter and the second parameter and an angle value between the first direction and the first vector to drive the robot. The mobile device performs the driving command to enable the robot dodging the at least one obstacle and following the target human, simultaneously. A controlling method of a robot for human following is also disclosed herein.
US11458624B2 Control server and method for controlling robot using artificial neural network, and robot implementing the same
Disclosed herein are a control server and method for controlling a robot using an artificial neural network, and a robot implementing the same. The robot includes a driver, a processor controlling the driver using an artificial neural network-based algorithm model, and a learning processor learning the algorithm model, where the algorithm model includes a first GAN (generative adversarial network) and a second GAN, the processor generates a plurality of real-like-fake images using a first generator included in a learned first GAN, the learning processor learns a second GAN based on a plurality of random texture rendered images and the plurality of real-like-fake images, and the processor generates a canonical image by inputting a real image to a second generator included in a learned second GAN, and controls the driver using the canonical image.
US11458622B2 System using natural conversation for monitoring a facility
A self-guided robot (bot) mechanism. An example bot may have a channel having an input for users, a cloud platform connected to the channel, a bot framework connected to the cloud platform, a web services module connected to the bot framework, and one or more drivers connected to the web services module. The one, the bot framework, the web services module and the drivers may be electronic hardware devices that effect their respective functions with a level of software managed and manipulated by the devices according to their respective algorithms.
US11458621B2 Systems, devices, articles, and methods for parallelization of robots in synchronous communication framework
A system including a controller, and at least two agents that communicatively access the controller. At least one of the agents is a robot. The system includes at least one processor communicatively coupled to the agents, and at least one storage device, communicatively coupled to the processor(s), that stores processor-executable instructions which, when executed, cause the processor(s) to: receive first job set of instructions provided by the controller, for a first agent included in at least two agents; and send, on behalf of the first agent, a sham status message before actual completion of the first job. The processor-executable instructions may, when executed, further cause the at least one processor to: update a data store to reflect the first job set of instructions; and receive for a second one of the at least two agents a second job set of instructions before completion of the first job.
US11458620B2 Correction method and system for constructing modular robot and control method for modular robot
The present disclosure relates to the field of modular robot control, and more particularly to a correction method and system for constructing a modular robot thereof. The correction method and system for constructing a modular robot according to the present invention can be corrected according to whether the assembly structure matches the target structure during the assembly of the modular robot, avoiding repeated assembly work by users, Which brings a good user experience to users.
US11458619B2 Method for controlling the motion of a robot arm, computing device and robot
A method for calculating an arm angle range of a robot arm includes: determining a pose at an tail end position of the robot arm; judging whether an angle of an elbow joint is within a limit thereof when an arm angle is 180 degrees; if yes, constructing a first position matrix characterizing the elbow joint by using the pose and the arm angle; constructing a second position matrix of the elbow joint by using DH parameters of other joints of the robot arm; calculating, according to the first position matrix and the second position matrix, a first arm angle feasible region satisfying a limit of a position joint; judging whether the robot arm has a secondary position joint; and intersecting with the calculated first arm angle feasible region to obtain an arm angle range if no secondary position joint is present at the robot arm.
US11458618B2 Collaborative operation support device
The collaborative operation support device includes a display device including a display area; and a processor configured to detect, based on an image in which the operator or the robot is represented, a position of a section of the robot in the display area when the operator looks at the robot through the display area, the section associated with an operation mode of the robot specified by means of an input device; select, in accordance with the specified operation mode of the robot, display data corresponding to the specified mode among display data stored in a memory; and display the selected display data in the display area of the display device in such a way that the selected display data is displayed at a position that satisfies a certain positional relationship with the position of the section of the robot in the display area.
US11458616B2 Robot
A robot includes a base, a robot arm having a first arm coupled to the base and rotating about a first axis, and a force detection unit provided in the base and detecting a force acting on the base or the robot arm, wherein the first arm is coupled to the base in a position shifted from a first center line passing through a center of the base and being parallel to the first axis, and a second center line passing through a center of the force detection unit and being parallel to the first axis is closer to the first axis than the first center line.
US11458611B2 Bendable partition for storage surface
A storage system is disclosed, and that may be in the form of a drawer, shelf, or the like. One or more customized, flexible partitions may be attached to a relevant storage surface. For instance, each partition may be cut to a desired length from a bulk source (e.g., a roll). Moreover, each partition may be flexed into a desired shape and then adhesively bonded to a relevant storage surface. A release liner may be removed from a bottom surface of the partition to adhesively bond the partition to the relevant storage surface. Double-sided adhesive tape could also be applied to the bottom surface of the partition to adhesively bond the partition to the relevant storage surface.
US11458607B2 Press device
A press device comprising a press ring for pressing together tubular workpieces in between, and at least a first and a second pivotable jaw is described. The jaws comprise engagement sections. The press ring comprises receiving sections for receiving the engagement sections of the press jaws. A first and a second surface of the receiving sections, contact the engagement sections. Each of the first and second surface comprises a planar surface. The engagement sections comprise contact surfaces. The contact surfaces oppose each other for applying a press force F. The contact surfaces each comprise at least one convex surface, such that a radius of curvature r of the first and the second contact surface is larger than half a width Wx, Wz, measured perpendicular to an axis of curvature, of the respective first and second contact surface.
US11458606B2 Shaft driving tool
A tool for driving a shaft a shaft within an apertured member, the tool incorporating a segmented sleeve having upper, lower, and medial segments, each segment having upper and lower ends, a hollow bore of the lower segment being helically threaded; a shaft biasing screw mounted within the lower segment's hollow bore, upper and lower joints, the upper joint connecting the upper end of the screw with the upper segment, and the lower joint connecting the medial segment with the lower segment; a first gear component attached to the upper segment; a support frame attached to the medial segment; a second gear component mounted rotatably upon the support frame, the second gear component being positioned for rotating the first gear component; a rotary power input stem fixedly attached to the second gear component; and a clamp or hook arms adapted for positioning the apertured member beneath the screw's shaft biasing lower end.
US11458600B2 Roller wrench
A roller wrench having a body with a circular chamber; a driving member being a regular polygonal component capable of rotating in the chamber; a plurality of rollers installed in the chamber, each of the rollers is located between a side of the driving member and a peripheral wall of the chamber; a reversing knob capable of driving the rollers to move in the chamber so that each of the rollers moves between two edges of each of sides of the driving member; and at least one elastic positioning component installed on one of the sides of the driving member, and capable of elastically moving into the driving member or protruding from a peripheral surface of the driving member. The elastic positioning component is moved into the driving member when being compressed; and is protruded from the driving member when not being acted on by an external force.
US11458599B2 Quick clamping device
The present invention relates to a quick clamping device. A pressing flange and a top plate are respectively installed on both sides of a bracket; one end of a top rod is rotatably connected with the top plate, and the other end is in threaded connection with a center pressing element; a slip ring copper sleeve is sleeved on the center pressing element; a synchronous slip ring can be sleeved outside the slip ring copper sleeve relatively movably; the outer end part of the slip ring copper sleeve is provided with a copper sleeve flange; a spring sleeved on the slip ring copper sleeve is arranged between the synchronous slip ring and the copper sleeve flange; both ends of the spring are respectively abutted against the synchronous slip ring and the copper sleeve flange; a plurality of pull rods are evenly distributed along the circumferential direction of a clamped element; one end of each of the pull rods is respectively hinged to the center pressing element, and the other end is a pressing end; the clamped element is positioned between the pressing flange and the pressing end of each pull rod; a connecting rod is connected between each of the pull rods and the synchronous slip ring; and both ends of the connecting rod are respectively hinged with the pull rods and the synchronous slip ring. The present invention has the advantages of novel structure, simple operation, small size, and the like.
US11458598B2 Holding head for a vacuum holding device for handling a plate-shaped workpiece and corresponding vacuum holding device
A holding head is provided for a vacuum holding device for handling a plate-shaped workpiece about an axis. An arrangement of operating elements on a base body of the holding head includes at least three operating elements connected as actuating elements in a double actuation circuit for releasing the plate-shaped workpiece. Two of the actuating elements are arranged on sides of the arrangement opposite to one another with respect to the position of the axis and the third actuating element is designed ring-shaped and surrounds the axis circumferentially.
US11458595B2 Tool attachment means for power trowels
A tool driver for a power trowel, the tool driver comprising a combination of a magnetic fastening arrangement and a hook and loop based fastening arrangement for releasably holding an abrasive tool to the tool driver, wherein the magnetic fastening arrangement is configured symmetrically around a rotational center of the tool driver, wherein the hook and loop based fastening arrangement is adapted to provide increased shear strength during abrasive operation of the tool, and wherein the magnetic fastening arrangement is adapted to provide increased pull strength during lifting of the tool driver.
US11458587B2 Carrier head having retainer ring, polishing system including the carrier head and method of using the polishing system
Some embodiments relate to a carrier head. The carrier head includes a housing configured to enclose a wafer, wherein the housing includes a retaining ring recess configured to circumferentially surround the wafer. A retaining ring, which includes a first ring-shaped layer and a second ring-shaped layer, is disposed in the retaining ring recess. The second ring-shaped layer is disposed deeper in the retaining ring recess than the first ring-shaped layer and separates the first ring-shaped layer from a bottom of the retaining ring recess. A hardness of the second ring-shaped layer is less than a hardness of the first ring-shaped layer.
US11458584B2 Machine tool, machined-object manufacturing method, and machining system
A machine tool includes a tool that machines a workpiece while being contact with the workpiece, a state-quantity-data acquisition unit that acquires state quantity data of the workpiece and of the tool, a state-quantity-estimation-data calculation unit that calculates state quantity estimation data from a simulation model including a device dynamic characteristic model indicating a dynamic characteristic of the tool and a workpiece model indicating a target shape of the workpiece, and a machining-state calculation unit that calculates machining state data indicating a machining state of the workpiece based on the state quantity data and the state quantity estimation data.
US11458580B2 Oversized part hold down apparatus
The present disclosure includes a part hold-down assembly for retaining an oversized part. The part hold-down assembly is aligned along a central force axis and applies a downward force onto the part. The part-hold down assembly includes a top plate, a bottom plate, and a compression assembly extending between the top and bottom plates. The compression assembly includes two, parallel biasing assemblies that extend along compression axes that are parallel to but offset from the central force axis. Each biasing assembly including an upper collar, a lower collar and a resilient biasing member, in one embodiment in the form of a coil spring, retained between the upper and lower collar. The parallel biasing assemblies are positioned on opposite sides from each other about the central force axis, and may be spaced away from the central force axis an equal distance.
US11458578B2 Method for the laser alignment of guide rails
A method includes producing a preform of a guide rail from steel, putting the preform in a holding device so that the preform is held fixed in position, analyzing the preform held in the holding device, a deviation from a straight shape being measured at a plurality of locations along the longitudinal axis. The method further includes irradiating the preform held in the holding device with a laser beam, a surface section being irradiated with the laser beam along the longitudinal axis at a plurality of locations, respectively on one of two side surfaces facing in opposite directions in relation to the first transverse axis, in such a way that it is heated into the plastic range.
US11458576B2 Methods and systems for quality inference and control for additive manufacturing processes
This disclosure describes an additive manufacturing method that includes monitoring a temperature of a portion of a build plane during an additive manufacturing operation using a temperature sensor as a heat source passes through the portion of the build plane; detecting a peak temperature associated with one or more passes of the heat source through the portion of the build plane; determining a threshold temperature by reducing the peak temperature by a predetermined amount; identifying a time interval during which the monitored temperature exceeds the threshold temperature; identifying, using the time interval, a change in manufacturing conditions likely to result in a manufacturing defect; and changing a process parameter of the heat source in response to the change in manufacturing conditions.
US11458575B2 Device and method for the preparation and operation on biological specimen
A device for shaping tissue includes a tip with an internal close-looped circulation system. The tip is configured to connect to tubes. One tube is configured to connect to a submersible cold-water pump. Another tube is an outlet. The tip has a sapphire window on one face and, on opposite face, a shaft with a laser fiber therein, and an opening for laser beam to shine through.
US11458568B2 Laser processing method
According to an embodiment of the invention, a laser processing method includes a first irradiation process and a second irradiation process. In the first irradiation process, a first laser light is irradiated on a first region of a processing object including a metal. A first output value of the first laser light is 3000 W or more. In the second irradiation process, a second laser light is irradiated on the first region. A second output value of the second laser light is not less than 60% and not more than 70% of the first output value.
US11458566B2 Monitoring material processing using imaging signal density determined from inline coherent imaging (ICI)
Systems, methods and apparatuses are used for monitoring material processing using imaging signal density calculated for an imaging beam directed to a workpiece or processing region, for example, during inline coherent imaging (ICI). The imaging signal density may be used, for example, to monitor laser and e-beam welding processes such as full or partial penetration welding. In some examples, the imaging signal density is indicative of weld penetration as a result of reflections from a keyhole floor and/or from a subsurface structure beneath the keyhole. The monitoring may include, for example, automated pass/fail or quality assessment of the welding or material processing or parts produced thereby. The imaging signal density may also be used to control the welding or material processing, for example, using imaging signal density data as feedback. The imaging signal density may be used alone or together with other measurements or metrics, such as distance or depth measurements.
US11458562B2 Method for welding electrical conductors by means of ultrasound and ultrasonic metal welding device
The invention relates to an ultrasonic metal welding device and a method for welding electrical conductors using a compression chamber that is adjustable at least in height and that is delimited on opposite sides by a section of a sonotrode as a first delimiting surface and by at least one section of a counter electrode (156) as a second delimiting surface, wherein for welding, the counter electrode and the sonotrode are displaced relative to one another. The counter electrode used is one that comprises sections (152, 154) of geometrically different working surfaces or is composed of at least two sections that are displaceable relative to one another.
US11458561B2 Electron beam column for three-dimensional printing device, three-dimensional printing device, and three-dimensional printing method
To provide a three-dimensional printing device that irradiates approximately the same ranges on the surface of a powder layer simultaneously with a plurality of electron beams having different beam shapes. An electron beam column 200 of the three-dimensional printing device 100 includes a plurality of electron sources 20 including electron sources having anisotropically-shaped beam generating units, and beam shape deforming elements 30 that deform the beam shapes of electron beams output from the electron sources 20 on a surface 63 of a powder layer 62. A deflector 50 included in the electron beam column 200 deflects an electron beam output from each of the plurality of electron sources 20 by a distance larger than the beam space between electron beams before passing through the deflector 50.
US11458559B2 Method and apparatus for arc welding by remote control
A welding apparatus can comprise an electrode holder configured to removably receive a consumable electrode and an actuator configured to move the electrode holder. The apparatus can comprise a base and an arm having first and second ends, where the first end is coupled to the arm such that the arm extends in a first direction that is angularly disposed relative to the base. The base can be configured to be placed relative to a workpiece such that the second end of the arm is disposed further from the workpiece than is the first end and the electrode, when received by the electrode holder, extends from the electrode holder toward the workpiece. A controller can be configured to adjust a rate at which the actuator moves the electrode holder relative to the arm, optionally based at least in part on an arc voltage measured across the electrode and the workpiece.
US11458557B2 Apparatus for soldering a terminal on window glass for a vehicle and a method thereof
An apparatus for soldering a terminal to which a solder alloy is attached on window glass for a vehicle, includes a terminal to which the solder alloy is attached; a coil unit including a coil which generates induction heat; a gripper which grips and releases the terminal and is configured to be movable upward and downward relative to the coil unit in a state of gripping the terminal; and a ferrite core unit including a ferrite core which is configured to be surrounded by the coil unit to receive the induction heat, and is configured to be movable upward and downward relative to the coil unit, wherein the solder alloy attached to the terminal, in a state of being in contact with the window glass, is melted by the induction heat from the coil unit and the ferrite core unit such that the terminal is attached to the window glass.
US11458556B2 Hand-held heating tool
A hand-held heating tool includes a handle unit, a pivot unit, a positioning unit, and a heating unit. The handle unit has a recess and a positioning portion. The pivot unit is pivotally connected to the handle unit and has a guiding groove and an abutment section. The positioning unit includes a positioning member, a control member, and an elastic member arranged between the control member and the abutment section. The control member is movably arranged in the guiding groove to actuate the positioning member to move relative to the recess so that the positioning member is selectively engaged with the positioning portion for adjusting a relative angle between the handle unit and the heating unit.
US11458545B2 Cutting insert and cutting tool
A cutting insert may include a base member including a plurality of tungsten carbide particles. In cases where a particle diameter distribution of the tungsten carbide particles is measured at intervals of 0.025 μm, the particle diameter distribution may include, as a maximum peak and a second peak, a first peak value that appears in a particle diameter range of 0.5-0.9 μm, and a second peak value that appears in a particle diameter range of 1.1-1.5 μm. A value of a particle diameter distribution frequency is larger than zero at a valley part where a value of the particle diameter distribution frequency reaches a minimum between the first peak value and the second peak value.
US11458531B2 Casting mold
A casting mold includes a cavity for molding a product, and a pouring basin and a passageway that guide molten metal into the cavity. The passageway includes, at portions thereof positioned below the pouring basin and the cavity, bent portions (a first bent portion, a second bent portion) that change the advancing direction of the molten metal, and the casting mold further includes a cover member, which covers the inner wall of the bent portion, allows the passageway positioned on the upstream side of the bent portion to communicate with the passageway positioned on the downstream side of the bent portion, and has a lower thermal conductivity than the base material of the mold.
US11458529B2 Chain tool
A chain tool includes a body having a driving hole, a stop portion, and a receiving portion located between the driving hole and the stop portion in an axial direction. A pressing member is received in the receiving portion and is movable relative to the body in the axial direction. A push member is in threading connection with the first threaded portion and is movable relative to the body between a first position distant to the stop portion and a second position adjacent to the stop portion. The pressing member is pressed by the push member and moves in an arcuate path when the push member moves between the first and second positions.
US11458526B2 Method of machining an opening in a plurality of blanks
A method and a system are disclosed for making an article of manufacture from a blank defining an internal opening. A stack of blanks are aligned and the internal openings of the blanks in the stack of blanks are machined by a rotary cutting tool to a finished dimension. The blanks are clamped together before machining in a numerically controlled machine tool. The blanks are subsequently formed individually in a sheet metal forming operation in which the inner perimeter of the internal openings is expanded as the blank is formed.
US11458525B2 Machine and method to work metal products
Machine to work oblong metal products, including a drawing apparatus to feed at least one of said metal products in a direction of feed and a work apparatus aligned in said direction of feed. The drawing apparatus includes a first drawing unit and a second drawing unit opposite each other with respect to said direction of feed. The first drawing unit and the second drawing unit define between them, in said direction of feed, a drawing channel for the at least one metal product. The drawing channel has a lying plane, defined by a plurality of anchoring inserts, for the at least one metal product, a supply apparatus being possibly present upstream of said drawing apparatus.
US11458520B2 Bender tool measuring system, apparatus, and method
A bender tool measuring system includes a conduit bender, a bent piece of conduit, and a measurement apparatus coupled to the conduit. The conduit bender includes a bender head comprising a hook and a handle coupled to and extending from the bender head. The measurement apparatus is configured to project an optical projection onto the handle of the conduit bender, and the location of the optical projection on the length of the handle indicates the position of the bent piece of conduit in relation to the bender head.
US11458516B2 Circular distribution apparatus
A circular distribution apparatus for distributing loose products has a top portion (17) with an inlet (19) positioned centrally relative to a vertical central axis, a base portion (7) comprising an annular horizontal floor (11); a plurality of openable and closable outlets (23) provided in the annular floor (11); a side wall (9) surrounding entirely the annular floor (11); a central elevation (13) disposed between the annular floor (11) and the inlet (19); and a vibrator (51) configured to vibrate the base portion (7) so that products received on the base portion (7) circulate around the elevation (13) on the annular floor (11). The top portion (17); the elevation (13); the annular floor (11); and the side wall (9) provide a housing (3) comprising a distribution chamber (5), where at least the elevation (13), the annular floor (11) and the side wall (9) are provided integrally.
US11458510B2 Blade cleaning and storage system
A device for cleaning and organizing sheetrock knives is disclosed. The device includes a panel having an orifice covered on at least one side with brush bristles. The panel has at least one slot for holding sheetrock knives and may contain additional compartments for holding utility knives and pencils. When a user places the device in a five gallon bucket, she may rinse and brush sheet rock knives using the orifice and cleaning liquid in the bucket or she may store the knives and other tools in the slots and other compartments.
US11458509B2 Sorter
The invention concerns a sorter having a base element that can be swiveled around a horizontal swivel axis with a number of support surfaces uniformly arranged about the swivel axis. Each of the support surfaces can be swiveled into a conveyor for conveying a product along a product stream and swiveled out of the conveyor for ejection of a product from the product stream.
US11458508B2 Sensor separation apparatus and method
A separation apparatus, comprising an identifier arranged to identify the particles in a group of particles that have a specific property, an affinity modifier arranged to modify an affinity of the identified particles relative to that affinity of non-identified particles in an group, and a separator arranged to separate the particles in the group based on their difference in the affinity.
US11458507B2 Systems and methods for dynamic processing of objects
A method of processing objects is disclosed using a programmable motion device. The method includes the steps of acquiring an object from a plurality of mixed objects at an input area, perceiving identifying indicia in connection with the object, assigning an intermediate station to a destination location for the object responsive to the identifying indicia in connection with the object, and moving the acquired object toward the intermediate station.
US11458505B2 Deblinding apparatuses and methods for screening
Deblinding apparatuses and deblinding methods are provided. A deblinding apparatus may include a support frame including a grid structure and multiple compartments. Multiple compartments may be formed by a respective portion of the grid structure and a respective set of support members. Further, multiple scattering members may be disposed within a compartment. Scattering members be removably affixed to a portion of the grid structure that forms a part of a compartment. Multiple unsecured objects may be placed within a compartment. When attached to a screen and in response to movement of support frame, at least one unsecured object of the multiple unsecured objects may collide with a first scattering member and with a surface of the screen to thereby cause deblinding of the screen. Sizes, shapes, masses, and morphologies of unsecured objects may be designed to optimize collision rates of unsecured objects with scattering members and with the screen assembly.
US11458503B2 Method for operating an extrusion system and extrusion system
A process for operating an extrusion system is provided. An extrusion device is provided that has at least two extrusion pistons operable with different feed ratios. The process involves storing a ratio of feed rates of the extrusion pistons in a storage device of the control device in dependence on the second signal. A least one drive device is actuated by the control device for displacing the two extrusion pistons into a start position, in which a plunger of the first extrusion piston substantially abuts the first cartridge of the cartridge device and a plunger of the second extrusion piston substantially abuts the second cartridge the cartridge device. The at least one drive device is actuated by the control device with a ratio of feed rates stored in the storage device of the control device for the extrusion pistons at user request.
US11458501B2 Liquid material discharge device, and application device and application method therefor
A liquid material discharge device and method capable of suppressing generation of bubbles caused with a rod raising operation in a negative pressure environment. In a liquid material discharge device used in a negative pressure space and including a storage container; a compressed-gas supply source pressurizing the storage container; a nozzle having a discharge flow path; a reciprocating valve rod; an actuator driving the valve rod; a valve seat having a communication hole that is communicated with the discharge flow path; and a discharge control device controlling the actuator to open and close the communication hole by a tip of the valve rod, the discharge control device controls an acceleration time Au in rising of the valve rod by the actuator to be held within a range of 2 to 300 [ms], thus preventing generation of bubbles caused with the rising of the valve rod.
US11458495B2 Paint shield
Embodiments are disclosed for an apparatus that enables the user to paint a surface and keep the paint focused in the desired area intended to receive the paint and minimize overspray. The disclosed apparatus is a paint shield. The paint shield includes an elongated planar body, a right fin, a left fin, and one or more reinforcing ridges that extend along the planar body. The paint shield can include an attached or attachable handle and the handle can rotate. The user may adjust the angle of the right fin and the left fin to provide additional protection from the side to protect a surface area from receiving any paint and then orient the back surface of the planar body against a surface to be painted. Once the paint shield is positioned, while holding the paint shield using the handle, the user paints the area not covered by the paint shield. The paint shield protects the surface that is covered by the paint shield so that no or minimal paint is deposited on that surface.
US11458494B2 Backpack sprayer
A backpack sprayer includes a housing, a spray nozzle assembly, a fan assembly and a switch assembly. The housing is configured to contain a liquid. The spray nozzle assembly is communicated with the housing, and is configured to spray the liquid out from the housing. The fan assembly is connected to the spray nozzle assembly, and is configured to provide the spray nozzle assembly with power to spray the liquid out from the housing. The switch assembly is connected to the spray nozzle assembly and electrically connected to the fan assembly, and is configured to control opening and closing of the spray nozzle assembly and start and shutdown of the fan assembly simultaneously.
US11458491B2 Fluid delivery assembly for a spraying apparatus
The present invention relates to a fluid delivery assembly for a spraying apparatus. The assembly comprises an outer cup, a lid having a fluid outlet adapted to couple the lid to the spraying apparatus, and a liner for holding paint. The fluid delivery assembly comprises an interlocking keyed geometry adapted to prevent rotation of at least one of the lid and the liner with respect to the cup. The interlocking keyed geometry comprises at least one of (a) at least one protrusion of the cup extending into at least one recess of the lid, and (b) at least one protrusion of the lid extending into at least one recess of the cup, wherein the liner is trapped between the protrusion and the recess. The invention also relates to liners for such fluid delivery assemblies, which may be provided as a set of liners having different inners volumes.
US11458488B2 Linearly actuated pause assembly for showerheads
A showerhead including a housing defining a plurality of nozzles and an inlet and having a water control assembly is disclosed. The water control assembly may be positioned at least partially within the housing between the plurality of nozzles and the inlet to control water flow from the inlet to the plurality of nozzles. The water control assembly including an actuator linearly movable along a length of the housing, a valve operably coupled to the actuator that rotates from a first position allowing fluid flow from the inlet to reach the nozzles to a second position reducing fluid flow from the inlet to the nozzles, and a valve driver coupled between the actuator and the valve, where the valve driver converts the linear motion of the actuator into a rotational movement of the valve.
US11458487B2 Filtered showerhead with multiple nozzle assemblies
A multi-mode showerhead having a housing with a front and a rear and an offset integrated water filter system incorporated into the showerhead. The multi-mode offset filtered showerhead has multiple nozzle assemblies, one of which is movable or rotatable and another of which is removable and may contain a unit to hold a water filter cartridge for insertion and removal from the integrated water filter system incorporated into the showerhead. A selector switch and other water flow control devices are used to selectively control the flow of water through the showerhead to the nozzle assemblies. The showerhead is mounted on a shower arm by way of a single water inlet on the rear of the housing and is fluidly connected to a hollow filter chamber in the integrated water filter system.
US11458485B2 Dust collector with negative pressure bagging
A negative-pressure dust collector system employs a dust separator device to separate the dust that is entrained in a stream of dust-laden air, exhausts the air stream to a vacuum-inducing machine, and discharge the separated dust downward into a bagger arrangement. The latter employs an open-bottom generally rigid hopper with a grid across its open bottom. A flexible dust collection bag is clamped onto an exterior of the hopper and hangs from the hopper. Under vacuum, the bag closes off the open bottom of said hopper. The grid has openings dimensioned so that dust in the container passes freely through the grid when the vacuum-inducing machine is shut off, but so that the bag may be sucked up against the grid, but not sucked into the open-bottom hopper when vacuum is applied. A flexible apron may be attached to the bottom of the hopper between the grid and the dust-collection bag.
US11458481B2 Impact crusher rotor position detection and control
An apparatus including a rotor position detection unit with a sensor configured to detect an angular position of a rotor of a horizontal shaft impact crusher, the rotor having attached thereon a group of hammers. A motor control system is configured to change the rotation speed of the rotor and an automation and control system is configured to control the motor control system in response to the detected angular position of the rotor. The rotor position detection unit is configured to detect a first and second angular position of the rotor corresponding to a first and second position of a hammer of the group of hammers attached to the rotor. The motor control system comprises a frequency converter and a brake configured to enable the stopping of the rotor.
US11458479B2 Home cardboard shredder
A cardboard shredder provides a shredder for cardboard to facilitate recycling while reducing storage space needed before cardboard enters a recycling stream cutting out the middle man, thus the recycler receives uncontaminated cardboard since it is not mixed in with other materials. The manufacturer receives clean shredded cardboard for reuse, reducing headcount for the plant by reducing and eliminating their shredders being jammed with plastic. Thus, an improvement in efficiency and reduction in costs of material and water.
US11458478B2 Integrated stage for holding rapid test reagent cards
An integrated stage for holding rapid test reagent cards includes two U-shaped sidewalls opposite to each other, a first receiving space, a second receiving space, and an elastic sheet. The U-shaped sidewalls cooperatively define the first receiving space. The second receiving space is formed in the first receiving space and is lower than the first receiving space. The elastic sheet is arranged on a short side of the first receiving space. The first receiving space is used for allowing the integrated stage to hold a first rapid test reagent card. The second receiving space is used for allowing the integrated stage to hold a second rapid test reagent card. The integrated stage utilizes the elastic sheet to hold and fix the first rapid test reagent card or the second rapid test reagent card.
US11458473B2 Systems and devices for analysis of samples
Systems and methods for analysis of samples, and in certain embodiments, microfluidic sample analyzers configured to receive a cassette containing a sample therein to perform an analysis of the sample are described. The microfluidic sample analyzers may be used to control fluid flow, mixing, and sample analysis in a variety of microfluidic systems such as microfluidic point-of-care diagnostic platforms. Advantageously, the microfluidic sample analyzers may be, in some embodiments, inexpensive, reduced in size compared to conventional bench top systems, and simple to use. Cassettes that can operate with the sample analyzers are also described.
US11458470B2 Systems and methods for analyzing platelet function
Provided herein are devices, systems, and methods for analyzing platelet function. In particular, provided herein are simple, portable, accurate and inexpensive small footprint platelet aggregometry devices, systems, and methods.
US11458461B2 Metal-semiconductor hybrid structures, syntheses thereof, and uses thereof
Aspects of the present disclosure generally relate to semiconductor nanoparticles, metal-semiconductor hybrid structures, processes for producing semiconductor nanoparticles, processes for producing metal-semiconductor hybrid structures, and processes for producing conversion products. In an aspect is provided a process for producing a metal-semiconductor hybrid structure that includes introducing a first precursor comprising a metal from Group 11-Group 14 to an amine and an anion precursor to form a semiconductor nanoparticle comprising the Group 11-Group 14 metal; introducing a second precursor comprising a metal from Group 7-Group 11 to the semiconductor nanoparticle to form a metal-semiconductor mixture; and introducing the metal-semiconductor mixture to separation conditions to produce the metal-semiconductor hybrid structure. In another aspect is provided a metal-semiconductor hybrid structure that includes a first component comprising a metal from Group 11-Group 14 and an element from Group 15-Group 16; and a second component comprising a metal from Group 7-Group 11.
US11458456B2 FCC catalyst prepared by a process involving more than one silica material
Process for the preparation of a catalyst and a catalyst comprising more than one silica is provided herein. Thus, in one embodiment, the invention provides a particulate FCC catalyst comprising about 5 to about 60 wt % one or more zeolites, about 10 to about 45 wt % quasicrystalline boehmite (QCB), about 0 to about 35 wt % microcrystalline boehmite (MCB), greater than about 0 to about 15 wt % silica from sodium stabilized colloidal silica, greater than about 0 to about 30 wt % silica from ammonia stabilized or lower sodium colloidal silica, and the balance clay and the process for making the same. This process results in attrition resistant catalysts with good performance.
US11458453B2 Molecularly imprinted polymer beads for extraction of metals and uses thereof
The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
US11458452B2 Highly mesoporous activated carbon
Highly mesoporous activated carbon products are disclosed with mesoporosities characterized by mesopore volumes of 0.7 to 1.0 cubic centimeters per gram or greater. Also disclosed are activated carbon products characterized by a Molasses Number of about 500 to 1000 or greater. Also disclosed are activated carbon products characterized by a Tannin Value of about 100 to 35 or less. The activated carbon products may be further characterized by total pore volumes of at least 0.85 cubic centimeters per gram and BET surface areas of at least about 800 square meters per gram. The activated carbon product may be derived from a renewable feedstock.
US11458444B2 Methods of forming a bicontinuous intraphase jammed emulsion gel and uses thereof
Provided herein is a method of forming a bicontinuous intraphase jammed emulsion gel.
US11458440B2 Thin-film composite polyamide reverse osmosis membrane with anti-bacterial and anti-biofouling effects and preparation method thereof
A thin-film composite polyamide reverse osmosis membrane with anti-bacterial and anti-biofouling effects and a preparation method thereof are disclosed. The preparation method includes: dissolving a highly water-stable metal organic framework CuBTTri in an n-hexane solution containing trimesoyl chloride by ultrasonic wave, immersing a polyethersulfone ultrafiltration membrane in an aqueous solution of m-phenylene diamine and taking out, and then immersing the ultrafiltration membrane in the trimesoyl chloride-n-hexane solution containing the aforementioned metal organic framework for reaction and modification, so as to obtain the thin-film composite polyamide reverse osmosis membrane. The resulting composite reverse osmosis membrane integrated with the anti-bacterial metal organic framework CuBTTri has a high reverse osmosis membrane permeability and possesses greatly improved and persistent anti-bacterial and anti-biofouling properties. The preparation method is simple and conducive to promotion, and has mild conditions.
US11458438B2 Polyurethane/polyvinylidene fluoride composite membrane for extracting organic sulfide from naphtha and preparation method therefor
The present invention relates to the field of composite membrane and discloses a polyurethane/polyvinylidene fluoride composite membrane for extracting organic sulfide from naphtha. The polyurethane/polyvinylidene fluoride composite membrane includes an active layer and a support layer where the active layer is a polyurethane casting membrane and the support layer is a polyvinylidene fluoride membrane. The polyurethane/polyvinylidene fluoride composite membrane is prepared by coating the active layer onto the support layer. At the same time, a preparation method for the polyurethane/polyvinylidene fluoride composite membrane is disclosed. The present invention has the following beneficial effects: the polyurethane/polyvinylidene fluoride composite membrane prepared in the present invention may be used to extract organic sulfide in naphtha with high separation efficiency. Further, the composite membrane almost does not change the octane number and the like of the raw material oil, thereby improving the extraction rate of the organic sulfide.
US11458433B2 Absorbent and process for selectively removing hydrogen sulfide
An absorbent for the selective removal of hydrogen sulfide over carbon dioxide from a fluid stream, wherein the absorbent contains an aqueous solution, comprising an amine of formula (I) and/or an amine of formula (II) wherein U—V—W is CH—O—CHR5, N—CO—CHR5 or N—CO—NR5; U′—V′—W is C—O—CR5; R1 is independently C1-C5-alkyl; R2 is selected from hydrogen and C1-C5-alkyl; R3 is independently selected from hydrogen and C1-C5-alkyl; R4 is independently selected from hydrogen and C1-C5-alkyl; R5 is selected from hydrogen, C1-C5-alkyl, (C1-C5-alkoxy)-C1-C5-alkyl, and hydroxy-C1-C5-alkyl; and x is an integer from 1 to 10. The absorbent has a reduced tendency for phase separation at temperatures falling within the usual range of regeneration temperatures for the aqueous amine mixtures and a low volatility in aqueous solvents.
US11458432B2 Rechargeable dehumidifier
Rechargeable dehumidifier including inside it the components it consists of, with the possibility that none of them project outward so that it can have an outward appearance without projections, as well as being simple to manufacture, comprising a casing with at least one first opening and open on the top, which configures a first internal cavity, a first lid arranged on top of the casing, provided in the first cavity with a container that in turn comprises a body open on the top that configures a second cavity, a second lid provided on top of the body and having at least one second opening; on top of the second lid may be provided a desiccant agent such that the water absorbed by it is collected in the body when it falls by gravity.
US11458430B2 Flush valve, dust collector and dust collection system
A flush valve, a dust collector provided with such a flush valve and a dust collection system, are disclosed. The flush valve includes a valve body and a valve spool. The valve body is internally provided with a fluid passageway. The valve body is provided with an inlet, a first outlet and a second outlet. The first outlet is fluidly connected to a device to be flushed. The valve spool includes a movable part, a fixed part and an elastic part, the fixed part being provided in the valve body, and the elastic part elastically connecting said fixed part to the movable part. One end of the movable part being provided with a first spool land for blocking the first outlet. The first spool land being configured to be pushed away from said first outlet by fluid in the fluid passageway when the pressure drops due to blockage.
US11458429B2 Air filter wear level estimation and replacement timing prediction method
A system is disclosed for use in inspecting a vehicle's air filter. The system includes a receptacle defining an enclosed interior space that is configured to receive the air filter, and a light source that is positioned within the receptacle. The receptacle includes an upper wall with an aperture that is arranged in generally parallel relation to the air filter, and the light source is configured to support the air filter such that the light source backlights the air filter to facilitate capture of an image of the air filter through the aperture in the upper wall of the receptacle.
US11458427B2 Fine fiber filter media and processes
Fine fiber products including fiber webs, as well as related assemblies, systems and methods, are described. In some embodiments, fiber webs described herein may include fine fibers and relatively low amounts of degraded polymer formed during a fiber extrusion process. The fiber webs may be used for filter media applications.
US11458424B2 Filter device
A filter device has a filter housing (1) having a fluid inlet (8) for unfiltered matter and having a fluid outlet (9) for filtrate, and has at least one one-piece or multi-part filter insert (15, 17) held in the filter housing (1). Filter insert (15, 17) can be cleaned using a backwash device (25) having at least one backwash element (31) in counter flow to the direction of filtration. The backwash element can be moved along the inside of the relevant filter insert (15, 17) by a fluid-conveying drive shaft (29) of a rotary drive (69, 71). The individual backwash element (31) has, at the end adjacent to this inside, at least one gap-shaped passage opening, which extends in parallel to the axis of rotation of the drive shaft (29) and which opens into a flow chamber connected to the drive shaft (29) in a fluid-conveying manner. At least one further backwash device (27) has a further backwash element (31). The fluid-conveying drive shaft (29) is divided into chambers (73, 75) separated from each other. One backwash element (31) of one backwash device (25) is connected to one of the chambers (73, 75). The other backwash element (31) of the other backwash device (27) is connected to another chamber (73, 75).
US11458423B2 Fluid filter with a filter connecting piece having an outer section, a middle section and an inner section
A fluid filter for a fluid device with one or more of a pump element and a solenoid valve in a motor vehicle, in particular for an ESP system. The fluid filter is formed by direct injection molding and has at least one filter connecting piece. The filter connecting piece has an outer section, a middle section, and an inner section. The outer section is in the form of a projection that is directed outwards with respect to the fluid filter. The inner section is in the form of a projection that is directed inwards with respect to the fluid filter.
US11458420B2 Purification of oil
A method and a system for purification of oil, said method comprising the steps of: —providing separation aid and oil to be purified to at least one sedimentation tank; —waiting for allowing a sludge phase to sediment to a bottom part of the sedimentation tank, said sludge phase comprising the separation aid together with impurities from the oil; —removing an oil phase not comprising said sludge phase from the at least one sedimentation tank; and —filtering said oil phase through a depth filter for removing any possible remaining separation aid and impurities.
US11458416B2 Carbon block/filtration bed/conical reactor with fluidized bed system allowing small sorbent particles to regenerate fluid during extracorporeal blood treatment
Methods and devices for powdered sorbent regeneration of biologic fluids are disclosed. The present invention includes three novel methods, which may be used singly or in any combination, for constraining or immobilizing powders so that they can be perfused with a biological fluid or dialysate: a porous carbon block filter, a filtration bed of very fine powder, and a cone-shaped reactor.
US11458413B2 Energy-efficient systems including vapor compression for biofuel or biochemical plants
Processes and systems are provided to compress vapors produced in distillation and recover the heat of condensation through vapor compression and to derive mechanical, thermal, and electrical energy from a combined heat and power system, while maintaining the plant's original ability to operate. The plant's existing distillation system, steam generation, and electrical demand determine the design basis for the retrofit system that is targeted at an optimized combination of energy usage, energy cost, and environmental impact. Vapor compression (by mechanical vapor recompression and/or thermal vapor recompression) minimizes the total energy usage. Optionally, combined heat and power provides a means of converting energy between fuel, electricity, and thermal energy in a manner that best complements plant requirements and energy economics and minimizes inefficiencies and energy losses.
US11458412B2 Controlled vapor delivery into low pressure processes
Provided herein are methods, systems, and device for control, delivery, and purification of low vapor pressure gases in conjunction with carrier gas in micro-electronics and other critical process applications. The present invention is based on the observation that when temperature and pressure of a device for delivering a gas stream are held constant, the concentration of vapor in the gas stream may be modulated based on the level of liquid within the chamber thereof.
US11458410B2 All dimensions free connection magnetic building block
The present disclosure provides a magnetic building block for connecting with other magnetic building block. The magnetic building block includes a base, a cover, at least one horizontal magnet and at least one vertical magnet. The base includes at least two vertical accommodating grooves and at least one horizontal accommodating groove. The cover is configured to connect with the base and cover the at least two vertical accommodating grooves and the at least one horizontal accommodate groove. The at least one horizontal magnet is located at the at least one horizontal accommodating groove. The at least two vertical magnets are located at the at least two vertical accommodating grooves respectively. Magnetic pole directions of two adjacent vertical magnets of the at least two vertical magnets are opposite to each other.
US11458408B2 Race royale gameplay through video game
The present disclosure relates to processing operations configured for generation and rendering of a race royale gaming environment that improves processing efficiency and racing gameplay in multiplayer scenarios. An exemplary race royale gaming environment provides a time-adjustable video game map configured to enable racing gameplay between a plurality of players (e.g., player-controlled vehicles) until an overall winner is determined. The race royale gaming environment is further configured to provide persistent vehicle upgrades that persist during at least one instance of racing gameplay (e.g., one or more races) in the race royale gaming environment. In other examples, the race royale gaming environment is configured to enable a player to challenge one or more other players to an elimination race within the time-adjustable video game map. The race royale gaming environment may further execute a predetermined number of rounds of gameplay that continuously reduces the time-adjustable video game map during racing gameplay.
US11458404B2 Systems and methods for verifying activity associated with a play of a game
A method for verifying behavior associated with play of a game is described. The method includes receiving a characterization of a first player from a user account as being abusive and accessing a recording of the behavior of the first player stored for a pre-determined time period in response to receiving the characterization of the first player. The method further includes analyzing, by an artificial intelligence model, the behavior of the first player to determine whether the behavior is abusive. The operation of analyzing whether the behavior of the first player is abusive is performed to determine whether the characterization of the first player is accurate.
US11458393B2 Apparatus and method of generating a representation of a virtual environment
A method of generating a representation of a virtual environment includes obtaining a mesh of at least part of the virtual environment; detecting the continuous and non-overlapping portions of that mesh, hereafter ‘patches’; populating a texture map with representations of the patches by, for successive patches in order of large to small, identifying a position on the texture map where a current patch meets a non-overwrite criterion, wherein the a non-overwrite criterion requires that texels corresponding to the current patch do not overwrite texels of any previously positioned patch, and successive positions for each current patch are tested at intervals starting from a common origin position; and associating the current patch with the identified position; setting colour values for the texels of the texture map responsive to colour information corresponding to the obtained mesh; and outputting the obtained mesh and texture map for use by a third party.
US11458391B2 System and method for improving smoothness in cloud gaming applications
A method for cloud gaming. The method including generating a video frame when executing a video game at a server. The method including performing a scan-out process to deliver the video frame to an encoder configured to compress the video frame, wherein the scan-out process begins at a flip-time of the video frame. The method including transmitting the video frame that is compressed to a client. The method including determining at the client a target display time for the video frame. The method including scheduling at the client a display time for the video frame based on the target display time.
US11458389B2 Vibration control apparatus
Disclosed herein is a vibration control apparatus that receives a vibration instruction and vibrates a vibration device in accordance with content obtained by correcting the content of the received vibration instruction, wherein the vibration control apparatus determines the correction content for vibration in accordance with a user using the vibration device.
US11458388B1 Automated controller configuration recommendation system
Various aspects of the subject technology relate to systems, methods, and machine-readable media for adjusting controller settings. The method includes receiving, through a controller associated with a user, controller input for software. The method also includes determining, based on the controller input, a user profile for the user comprising at least a skill level and an input tendency of the user. The method also includes providing suggested adjustments to the controller settings intended to improve performance of the user in relation to the software, the controller settings comprising at least one of controller sensitivity or controller assignments. The method also includes receiving approval of the user to implement the suggested adjustments to the controller settings. The method also includes adjusting the controller settings based on the approval of the user.
US11458383B2 Skateboard truck with inverted king pin and integrated kingpin fastener
A skateboard truck includes a metal bolt called a kingpin and a threaded fastener, called a hex nut, which when combined hold the two main components of a truck together: the baseplate, which is mounted to the bottom surface of the skateboard deck; and the turning part of the truck called the hanger, which is mounted onto the baseplate by means of the kingpin, and affixed tightly into the baseplate by means of a threaded hex nut. Two bushings placed along the shaft of the kingpin and on either side of a flange protruding from the hanger hold the hanger in place by the tightening of the kingpin into the threaded shaft nut fastener. The kingpin is oriented such that a threaded portion of the kingpin (on an end opposite a bolt head portion) is generally facing towards a bottom surface of the skateboard deck.
US11458382B2 Immersive upper limb rehabilitation training system
An immersive upper limb rehabilitation training system includes a dual-arm rehabilitation robot, a base, a position tracker, a VR headset, a force-feedback glove, a host computer control center and passive compliant end-effectors. The dual-arm rehabilitation robot is mounted on the base, and drives an arm of a patient to move through two passive compliant end effectors. The visual sensor is used for recording a motion of an upper limb of the patient and feedback-controlling a motion of the dual-arm rehabilitation robot. The position tracker is used for real-time collecting position and posture information of the arm and transmitting it to the upper computer control center. The two passive compliant end-effectors are respectively worn on a forearm and an upper arm of the patient. The upper computer control center is used to provide a quantitative index and control a display of a training screen.
US11458380B2 Retractable gaff guard
A retractable gaff guard which can be attached to a climber for use in protecting the gaff of a climber. A small retractable reel attached to a gaff guard via a cord woundable in an out of a housing of the reel that can attach on the outside of the leg iron of a climber. The cord is moveable between a retracted position and an extended position. Attached to the cord is a protective body that has a cavity which is dimensioned to receive a gaff of a climber.
US11458378B2 Baseball simulation and gamification system
An interactive baseball gamification system can be facilitated via the use of sensors, data tracking, gamification, and virtualization. A first user can play against a second user in real-time, near real-time, or based on historical user data. Additionally, the first user can be geographically remote from the second user. The interactive baseball gamification system can be used to train baseball players or baseball teams. Alternatively, the interactive baseball gamification system can be used for recreational purposes to pit users against each other.
US11458376B2 All surface, counter-weighted, teetering, free-standing, mobile field sport shooting target device and methods of making and using same
A mobile, free standing field sport shooting target device, including a pole having a first end and a second end, wherein an opening is located at the first and second ends of the pole, a counter weight plate having a plurality of openings, wherein the counter weight plate is located adjacent to the first end of the pole, and a collar operatively connected to the first end of the pole, wherein the collar has a first end and a second end such that the counter weight plate is located adjacent to the first end of the collar and the collar is used to retain the counter weight on the first end of the pole, and wherein a distance between the first end of the pole and the second end of the collar can be adjusted.
US11458374B2 Golf club
A shim or badge is affixed to a golf cub body to produce a cap-back iron, giving the appearance of a hollow-body iron. In this way, the golf club can be manufactured with the performance benefits of a game improvement iron, while providing the appearance of a blade, player's iron, and/or a hollow-body iron. For example, by using a lightweight and rigid shim or badge to close a cavity opening and extend into the toe portion in the golf club body, the golf club head can provide increased stiffness in the topline, while lowering CG. Various shim or badge arrangements and materials can be used, and a filler material and/or damper can be included within the cavity to improve sound and feel, while minimizing loss in COR.
US11458373B2 Golf club heads with internal undercuts
Described herein is a hollow body iron-type golf club head having a sole and ballast configured to relieve stress within a forward portion of the sole. In a first configuration, the golf club head comprises a ballast undercut for relieving stress. In other configurations, the ballast undercut is combined with additional stress relief features, such as a cascading sole near the face sole juncture, for further reductions to face thickness.
US11458367B2 Filtering control signals
An exercise system includes a load bearing element having a control element. It further includes a resistance mechanism responsive to a signal from the control element. The signal from the control element is selectively rejected based on state information relating to a state of the load bearing element.
US11458366B2 Haptic feedback
An exercise accessory includes a load bearing element. It further includes a haptic actuator. In response to an indication of an event pertaining to a load on the load bearing element, the haptic actuator is configured to generate a vibration pattern corresponding to the event. Different events are associated with different vibration patterns.
US11458362B1 Swing analysis system
A swing analysis system is disclosed herein. The swing analysis system includes a motion capture system and a force measurement assembly configured to receive a user; and at least one data processing device operatively coupled to the motion capture system and the force measurement assembly, the at least one data processing device configured to determine positional information for the one or more body segments of the user from the output data of the at least one motion capture device and output forces and/or moments from the force measurement assembly, the at least one data processing device further configured to determine one or more swing performance parameters for the user using at least one of: (i) the positional information of the one or more body segments of the user from the at least one motion capture device, and (ii) the output forces and/or moments from the force measurement assembly.
US11458361B1 Lung exercise apparatus and method
A lung exercise apparatus and method with an enclosure, with an inside, an outside and an open top, configured to hold a liquid of a first density. An additive to the liquid that increases the first density such that a person in the liquid is more buoyant. Weight removably connectable with the person such that a person in the enclosure is held vertical in the enclosure and partially immersed in the liquid below a surface of the liquid and with some of a person's body above the surface of the liquid. And a harness that is removably connectable with the person to hold some of the person's body above the surface of the liquid where lungs in a person's body are below the surface of the liquid.
US11458358B1 Climbing exercise apparatus
An exercise apparatus having multiple exercise modes of operation may include a frame supporting generally vertically oriented reciprocating members spaced apart and in substantial parallel relationship to one another. Reciprocating leg members may include foot supports secured at the lower distal ends thereof. Reciprocating arm members may include hand grips coupled proximate the upper distal ends of the arm members. The arm members and leg members may be operably coupled in multiple configurations for a user to perform various climbing exercise movements.
US11458349B1 Weightlifting exercising system
A weightlifting exercising system includes a frame having a pair of columns. A pair of lifting assemblies is provided and each of the columns has one of the lifting assemblies mounted thereon. The lifting assemblies each include a mount and an axle extending through the mount and rotational relative to the mount. A first arm is fixedly attached to the axle. A second arm is rotationally coupled to the axle. A lift angle is defined between the first and second arms and is alterable from 0° to 180°. A locking member releasably locks the second arm with respect to the axle such that the lift angle is releasably retained. One of the first and second arms has a handle attached thereto and the other of the first and second arms has a weight receiver attached thereto. One or more weight plates is removably positionable on the weight receiver.
US11458347B2 Kettlebell handle with weight attachment means
An exercise device includes a rigid handle having a lower end and an upper end. The upper end is adapted for grasping by a person's hand, and the lower end is fixed with a shaft receiver. A bottom end of the shaft receiver is adapted for receiving a top end of a rigid shaft that is adapted to receive one or more weights. A weight stop projects away from a lower end of the rigid shaft to prevent the weights from sliding off of the rigid shaft. In use, with one or more of the weights fixed on the rigid shaft, and with the top end of the rigid shaft fixed with the shaft receiver, the person may grasp the handle to perform exercises. A latch of the shaft receiver selectively locks the rigid shaft with the shaft receiver. The shaft and shaft receiver may include cooperative screw threads.
US11458346B1 Portable and variable exercise device
The apparatus provides an exercise device that is portable, versatile, and enables the user to match the resistance of the device with the normal physiologic length-tension relationship of skeletal muscle. The device adds resistance in the form of cartridges that are stackable to summate resistance and can connect to a variety of attachments for use with arms, legs, or trunk, i.e., handle, bar, loop, etc. Given the device's portability, it can be used freestyle or mounted to various surfaces.
US11458344B2 Jump rope with spring-supported collet handle
In one example in accordance with the present disclosure, a jump rope handle assembly is described. The jump rope handle assembly includes a handle having a longitudinal axis. A shaft assembly is disposed within the handle. The shaft assembly is to receive a jump rope section and is to rotate and slide within the handle. The shaft assembly includes a collet to retain the jump rope section. The jump rope handle assembly also includes a spring to compress between the shaft assembly and an interior impact surface of the handle.
US11458341B2 System and method for monitoring differential pressure across a dry pipe valve in a fire suppression system
A differential pressure monitoring system includes a differential pressure monitoring device and at least one client device. The differential pressure monitoring device includes a water pressure sensor that detects a water pressure at an inlet of the dry pipe valve, a valve air pressure sensor that detects an air pressure at an outlet of the dry pipe valve, and a control circuit that computes a ratio of the water pressure and the air pressure, predicts whether a valve tripping event is expected to occur based on the computed ratio, and in response to predicting that the valve tripping event is expected to occur, provides a prediction that the valve tripping event is expected to occur for remedial action. The system includes at least one client device that receives the prediction from the control circuit and presents display data regarding the prediction.
US11458339B2 Hot melt safely door holder device
A hot melt safety door holder device includes: a first fixing part on one side of swing end of swing door sheet; a holder with a transverse through hole and the outer hole end faces towards the first fixing part; a second fixing part in the transverse through hole, the first radial end faces towards the outer hole end of transverse through hole, the second radial end faces towards the inner hole end; a conically cylindrical space, formed between the periphery of the second fixing part and the transverse through hole, and the inside and outside diameters of the end between the transverse through hole and the second fixing part corresponding to the space tapering end of conically cylindrical space are fitted with each other. The shape of the low-melting metal material filled in the conically cylindrical space matches the shape of conically cylindrical space, resulting in equal wall thickness.
US11458338B2 Facial shielding system for protection from environmental hazards
A system which protects the user from electromagnetic radiation, in particular the eyes, face and/or head from UV radiation and/or excessive light as required, while also protecting from thrown particles, projectiles or fluids from striking a user, in particular the eyes, face and/or head, and at the same time providing clean air to breathe.
US11458334B2 System and method for diagnosis and treatment
A method may include acquiring a first image including a target point and a first reference point, the target point corresponding to at least one part of a subject, the first reference point corresponding to a first marker disposed on the couch of the medical device; determining a first spatial position of the first marker, the first spatial position corresponding to a first working position of the couch; determining a first spatial position of the at least one part of the subject based on the first image and the first spatial position of the first marker; determining a second spatial position of the first marker, the second spatial position corresponding to a second working position of the couch; determining a second spatial position of the at least one part of the subject based on the second spatial position of the first marker and the first spatial position of the at least one part of the subject. In some embodiments, the method may further include adjusting the second working position of the couch based on the second spatial position of the at least one part of the subject.
US11458328B2 Photobiomodulation therapy device accessories
A light therapy device mounting system may include an elongate pole comprising a plurality of holes, a first portion, a second portion, and a coupler configured to couple the first portion and the second portion. In some embodiments, the system includes a slider mount slidably coupled to the elongate pole via at least one hole of the plurality of holes, a top bracket slidably coupled to the first portion of the elongate pole, and a bottom bracket slidably coupled to the second portion of the elongate pole. The top bracket may include a top hook for receiving a top portion of a door, and the bottom bracket may include a bottom hook for receiving a bottom portion of the door.
US11458327B2 High-power pulsed electromagnetic field applicator system
Described herein are high-power pulsed electromagnetic field (PEMF) applicator systems. The systems can comprise a base housing including a controller configured to generate a low-power control signal and one or more applicators coupled to the base. Each applicator can include a drive circuitry comprising a generator configured to receive the low-power control signal and to produce, in the applicator, a high-power, pulsed electromagnetic field signal based on the low-power control signal. The high-power pulsed electromagnetic field signal can have a power of greater than 40W. Each applicator can further include a coil circuit configured to emit the high-power pulsed electromagnetic field signal, and an electromagnetic energy shield disposed between the drive circuitry and the coil circuit.
US11458323B2 Plasma treatment unit
A plasma treatment unit having a high-voltage stage (5, 6), arranged in a housing, for generating high-voltage signals suitable for the generation of a plasma, and having a head part (2) which is connectable to the high-voltage stage (5, 6) and in which there is situated an electrode arrangement (13) shielded by a dielectric (9), is suitable for plasma treatments in particular in the body interior by virtue of the fact that the head part (2) has an elongate transition piece (10) which is attachable to the housing and on that end of which which is not connectable to the housing there is arranged a treatment head (16, 16′), the dimensions of which perpendicular to the longitudinal direction of the transition piece (10) greatly exceed the dimensions of the transition piece (10), and that, in the treatment head (16, 16′), the electrode arrangement (13) forms a spatially closed flexible sheath (12) around a resiliently elastic core (14) and is covered at its outer lateral surface by a thin layer (15) of the flexible dielectric (9), such that the treatment head (16, 16′) can, as it is inserted into a body interior, assume the shape of the surrounding tissue in the body interior.
US11458320B2 Method of cardiac resynchronization therapy
Various embodiments include methods of cardiac resynchronization therapy (CRT). Various embodiments may include: generating, using a processing unit, a cardiac activation map including a three-dimensional (3D) heart model of the heart that shows coronary vessels of a patient and shows the propagation of electrical signals through the 3D heart model; determining the location of a left bundle branch block (LBBB) based on the cardiac activation map; implanting a first pacing device and a second pacing device into the patient; stimulating the His Bundle of the heart using the first pacing device; and stimulating the left ventricle (LV) of the heart at a position downstream of the LBBB with respect to a direction of electrical conduction through the LV using the second pacing device after stimulating the His bundle.
US11458319B2 Adjustable sensing in a His-bundle pacemaker
Systems and methods for pacing cardiac conductive tissue are described. An embodiment of a medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses to stimulate a His bundle, and a cardiac event detector to detect a His-bundle activity within a time window following an atrial activity. The cardiac event detector may use a cross-chamber blanking, or an adjustable His-bundle sensing threshold, to avoid or reduce over-sensing of far-field atrial activity and inappropriate inhibition of HBP therapy. The electrostimulation circuit may deliver HBP in the presence of the His-bundle activity. The system may further recognize the detected His-bundle activity as either a FFPW or a valid inhibitory event, and deliver or withhold HBP therapy based on the recognition of the His-bundle activity.
US11458316B1 Method and system for ocular stimulation
Devices and methods to deliver microcurrent stimulation therapy to the human body, when connected to a micro-stimulation current-generating apparatus. The method of applying microcurrent stimulation therapy to key points around the eye for treatment of problems such as macular degeneration, retinitis pigmentosa, glaucoma, optic neuritis and other eye-related or nerve-related conditions, as well as other diseases, such as Bell's Palsy, requiring localized stimulation to the eyes and/or on other body parts.
US11458314B2 Method for configuring an electroanalgesia and electrotherapy apparatus
A method for configuring an electroanalgesia and electrotherapy apparatus using wireless control, with multiple stimulators, particularly used in the segment of pain control and aid in postoperative tissue repair and reduction of measures and body weight. According to the embodiments, a user with electrodes generically distributed simultaneously in several parts of the body, where at the pain site the frequency is from 80 Hz to 300 Hz or 1000 Hz and then to a range of 15 Hz to 35 Hz or among 0.5 Hz and 10 Hz on that electrode, and at distant points, for example, in upper or lower limbs the frequency is from 0.5 Hz to 10 Hz and, so the person can be submitted to this analgesia procedure, according to the pre-determined frequencies, pulse width and pulse form already pre-defined.
US11458312B2 Implantable medical systems, devices, and methods for affecting cardiac function through diaphragm stimulation, and for monitoring diaphragmatic health
Devices, systems and methods provide forms of asymptomatic diaphragmatic stimulation (ADS) therapy that affect pressures within the intrathoracic cavity, including: 1) dual-pulse ADS therapy, during which a first ADS pulse is delivered during a diastolic phase of a cardiac cycle and a second ADS pulse is delivered during a systolic phase, 2) paired-pulse ADS therapy, during which a first ADS pulse is delivered, closely followed by a second ADS pulse, with the second ADS pulse functioning to extend or enhance a phase of a transient, partial contraction of the diaphragm, and 3) multiple-pulse ADS therapy, during which a stream of ADS pulses is delivered, wherein the time between pulses is based on heart rate. Devices, systems and methods also monitor electromyography (EMG) activity of the diaphragm relative to baseline activity to assess the health of a diaphragm subject to ADS therapy and to adjust ADS therapy parameters or sensing parameters.
US11458311B2 Non-invasive nerve activator patch with adaptive circuit
A topical nerve activation patch includes a flexible substrate, a dermis conforming bottom surface of the substrate comprising adhesive and adapted to contact a dermis of a user, a flexible top outer surface of the substrate, a plurality of electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and coupled to the flexible substrate, a power source, and electronic circuitry that generates an output voltage applied to the electrodes. The electronic circuitry includes a controller, a voltage monitoring circuit coupled to the controller, a current monitoring circuit coupled to the controller, a switch coupled to the controller and a two stage boosted voltage circuit coupled to the switch and the power source that is configured to increase a switch voltage level to approximately a half value of a final output voltage before increasing to the final output voltage.
US11458310B2 Electro-stimulation type indoor bicycle
An electrical stimulation indoor bike includes a stationary bicycle; an electrical stimulation unit connected to the stationary bicycle either with wire or without wire, and including an electrode pad for applying electrical stimulation to a user's body; and a control unit to control electrical stimulation of the electrical stimulation unit in accordance with an exercise mode of the stationary bicycle. By the electrical stimulation indoor bike, a variety of electrical stimulation according to pedal movement is applied to a body through an indoor bike connected with a low-frequency stimulator, thereby maximizing exercise effect.
US11458306B2 Termination of a shield within an implantable medical lead
A shield located within an implantable medical lead may be terminated in various ways. The shield may be terminated by butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. For lap joints, a portion of an outer insulation layer may be removed and a replacement outer insulation layer is positioned in place of the removed outer insulation layer, where the replacement layer extends beyond an inner insulation layer and the shield. The replacement layer may also lap onto a portion of the insulation extension. The barbs may be located between the replacement layer and the inner insulation layer or the insulation extension. The shield wires have ends at the termination point that may be folded over individually or may be capped with a ring located within one of the insulation layers of the jacket.
US11458303B2 Implantable medical leads having fewer conductors than distal electrodes
Implantable medical systems include implantable percutaneous medical leads and/or implantable medical lead extensions that have fewer conductors than distal electrodes, or distal connectors for extensions, by having one or more conductors be electrically coupled to multiple distal electrodes. The multiple distal electrodes may span a general area of a body of a patient that includes a specific point that requires therapy, such as multiple vertebral segments. Because all distal electrodes spanning the general area that are coupled to an active conductor will output the stimulation therapy, the specific point within the general area will receive the therapy even without identifying which electrode is most effective. Bipolar and unipolar stimulation modes may be used. Multiple leads may be used where each lead has more distal electrodes than conductors. Additionally, a single lead may have more distal electrodes than conductors while also carrying multiple stimulation waveforms.
US11458300B2 Overmolded segmented electrode
One aspect is forming a medical lead for implantation. The method includes forming a plurality of non-ground electrodes, at least one non-ground electrode having a plurality of segments. Overmold portions are formed for the at least one of the plurality of non-ground electrodes, including keys and tabs. One of a plurality of conductors is attached to one segment of the at least one non-ground electrode using the keys and tabs. The non-ground electrodes and plurality of conductors are assembled into electrode assembly and the overmold portions are reflowed. The reflowed electrode assembly is then ground to form the medical lead.
US11458293B2 Self-flushing connector
A self-flushing connector includes a housing having a cavity, a first inlet port, a second inlet port, and an outlet port. A collapsible valve is disposed within the cavity. A first flow path extends from the first inlet port to the outlet port. The first inlet port and the second inlet port are fluidly connected through a gap defined between the body of the collapsible valve and an inner wall of the housing defining the cavity. A second flow path extends from the second inlet port to the first flow path. When the collapsible valve is in a closed state, the collapsible valve fluidly disconnects the second flow path from the first flow path while allowing fluid to flow through the first flow path. When the collapsible valve is in an open state, the second flow path is fluidly connected to the first flow path.
US11458292B2 Rotatable infusion device and methods thereof
An infusion set that has a base having an opening to receive a cannula device, the base having a lower base part and an upper base part, wherein the upper base part is coupled to the lower base part and is rotatable relative to the lower base part and a connector that has a fluid connector tube. The connector prevents the upper base from substantially rotating relative to the lower base and the fluid connector tube is in fluid connection with the cannula device when the connector is coupled to the base.
US11458283B2 Urinary catheter assemblies and packaging for such assemblies
A urinary catheter assembly (10) Includes a catheter tube (14), a connector (16), and a urine collection bag. The assembly further includes a package with a body receiving the catheter tube (18) and the urine collection bag (18) is in its compact configuration. The bag (18) may be variously configured, such as having a non-woven fabric backing portion and/or an outer adhesive or containing a superabsorbent polymer additive.
US11458279B2 Sleep enhancement system and wearable device for use therewith
A system in which a wearable device detects an electroencephalographic (EEG) response from a user during sleep-related activity, e.g. trying to fall asleep, being asleep or waking up, and outputs an audio signal that is tailored, based on the EEG response, to enhance the user's sleep experience. In particular, an audio, thermal and/or olfactory signal may be used to facilitate any one or more of (i) a smooth path into REM sleep, (ii) a reduced potential for sleep being disturbed, and (iii) exit from sleep at an optimum time. In one example, the system synchronizes properties of an audio signal comprising a dominant white and/or pink noise component with the identified sleep-related parameters. The synchronized properties can include any of intensity, frequency, tone, volume and rhythm.
US11458278B2 Gas supply device for respiration and control method therefor
The device of the invention is equipped with a pressure sensor and a control unit, and the control unit judges a point at which a pressure gradient calculated from a signal of the pressure sensor becomes larger in the absolute value than a pressure gradient threshold as an inspiration sensing point and starts respiratory gas supply. In addition, the device judges from a frequency of the inspiration sensing point during predetermined time whether a pressure gradient threshold used as a criterion for the inspiration sensing point corresponds to an activity state of the user, and when the pressure gradient threshold does not correspond to the activity state, switches the pressure gradient threshold to another threshold and thus fits the pressure gradient threshold to the activity state.
US11458277B2 Bioactivation method for enhancing neural activity and blood circulation activity of living body
Provided are a bioactivation method for enhancing a neural activity and/or a blood circulation activity of a living body and a hydrogen generating device for executing this method. In the method, a gas mixture containing hydrogen and oxygen at predetermined concentrations is suctioned by spontaneous breathing continuously for a predetermined time. Moreover, this hydrogen generating device for executing the bioactivation method for enhancing a neural activity and/or a blood circulation activity of a living body includes a body cover member including a battery, a control substrate for controlling power supply from the battery, and a pair of positive/negative electrodes electrically conducted with or shut down from a positive electrode and a negative electrode of the battery by the control substrate.
US11458271B2 Ultrasonic welding of fabrics for sleep apnea treatment
A respiratory apparatus may employ ultrasonic welds. The ultrasonic welding may be used to join a variety of headgear, mask and accessory components. This process may enhance comfort, fit and/or performance of the joined components and/or overall mask assembly. A component may be a single layer component such as a textile or fabric, or a composite or multiple layer component such as fabric and foam composites, or outer fabric layers and inner spacer fabrics. Further, a component may be a strap, some other headgear component, a mask component, an accessory component or the like.
US11458270B2 High flow therapy device utilizing a non-sealing respiratory interface and related methods
A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient, the system including a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the pressurized respiratory gas is controlled by a microprocessor.
US11458254B2 Adjustable injection device
An apparatus and method for adjusting an injection device for administering a substance that includes a device housing with an array of fastening points. The apparatus has at least two housing-like shells, each having at least one holding device and at least one blocking device for attaching to the housing. The holding device of a first shell can be attached to a fastening point, and the holding device of a second shell can be attached to a further fastening point. Upon attaching all of the plurality of housing-like shells to the housing, the blocking devices of the plurality of housing-like shells prevent the disengagement of the plurality of housing-like shells from the housing by blocking detachment of the holding devices from the fastening points. At least one of the housing-like shells comprises an electronic assembly and shell attachment to the housing activates the electronic assembly.
US11458248B2 Catheter insertion device
A catheter insertion device (18) includes a housing (12) with a base (14), a catheter (28), an introducer needle (30) and an actuator (26) mounted within the housing. The catheter (28) and needle (30) are coupled to the actuator (26) and movable between a first position where the catheter and needle are retracted within the housing and a second position where the catheter and needle extend from the housing, and where the needle retracts into the actuator when the catheter and needle reach the second position. The actuator (26) has a detent (84) that engages a first recess (76) to require a predetermined force to depress the actuator (26) which is greater than the force necessary to slide the actuator (26) to the second position where the detent (84) engages a second recess (80) in the housing (12) to hold the actuator in the deployed position.
US11458245B2 Accessory holder with syringe assembly removal tool
A medical procedure accessory components holding unit and methods of using thereof. The accessory holder is designed to hold and store one or more components or medical devices that could be used in a medical procedure, particularly medical devices, for applying an anesthetic. The accessory holder may include four (4) medical device storage or use modules: a syringe disposal device module, a dispensing tool module, a canister module, and a syringe attachment module.
US11458244B2 Irrigating surgical apparatus with positive pressure fluid
A surgical instrument including an elongated tubular body portion and an irrigation assembly. The elongated tubular body portion extending distally to an end effector and defining an interior cavity. The irrigation assembly includes an inlet port and a shaft assembly supported by the elongated tubular body portion. The inlet port and the shaft assembly are disposed in fluid communication with one another to deliver fluid from the inlet port into the interior cavity of the elongated tubular body portion to irrigate the interior cavity with positive fluid pressure.
US11458243B2 Irrigation device and system for delivering pressurized fluid to same for wound lavage and biofilm control
A medical device is provided for irrigation of a patient wound site. The device contains a tube having a proximal portion adapted to receive an irrigation solution, a distal portion having a nozzle and an intermediate portion for transporting the solution. The tube has a barrel portion that may be manipulated by a user to position the device relative to the wound site. A distinctive nozzle has a body formed with a distally leading channel presenting a semispherical first spatial conformation and a proximally leading opening formed in the body presenting a second spatial conformation intersecting the semispherical terminus. This geometry, derived from principles of flow mechanics discussed herein, defines what will be described as an “effective diameter” of the nozzle. An assembly and system utilizing the device am also disclosed. The invention utilizes a fluid-isolating durable peristaltic pump for a continuous flow of irrigation solution, along with a single use tube set that embodies the device.
US11458242B2 Liquid-gas separator
A method and system for separating a flow of matter is shown and described. The system includes one or more flow separation devices, one or more surgical instruments, and one or more suction sources. In some embodiments, the flow of matter comprises biological material. In some embodiments, the flow of matter comprises surgical waste.
US11458241B2 High flow manifold
Implementations described herein include a system for guiding medical waste fluid into a medical waste collection canister. The system includes a manifold and a filter. The manifold includes a top surface and a sidewall extending from the top surface in a first direction. The top surface and the sidewall define an interior chamber of the manifold. The top surface includes an inlet port and a vacuum port disposed therein. The inlet port connects to a source of medical waste fluid and the vacuum port connects to a vacuum source. The manifold can be formed from a first polymer. A filter is positioned within the interior chamber of the manifold and immediately upstream of the vacuum port so as to filter air flowing into the vacuum port. The filter extends away from the top surface of the manifold in the first direction and the filter is formed from a second polymer. The filter is fused to a surface of the interior chamber of the manifold or to a peripheral surface of the vacuum port so as to form a fused interface, and not merely a press fit connection.
US11458240B2 Biological component collection system with internal pressure sensor and method
A blood component collection system, which is one form of a biological component collection system, is equipped with a centrifugal separation device and a biological component collection device. The biological component collection device comprises a pressed soft portion pressed by a load detecting unit. The centrifugal separation device includes a collection and returning pump, and a control unit having an internal pressure computation unit which calculates a circuit internal pressure of the biological component collection device on the basis of a detection value of the load detecting unit. The internal pressure computation unit performs a zero reset process of setting a pressure value corresponding to the detection value of the load detecting unit, so as to become zero at each instance of a predetermined timing at which the collection and returning pump is stopped.
US11458236B2 Reduced leaching of a ligand
A column for removal of a component from a fluid is disclosed. The column has a compartment with a cross sectional area. The compartment contains beads having a diameter. A ligand selected to bind to the component is coupled to the beads. The cross-sectional area and bead diameter are selected to maintain a flow velocity of the fluid within the compartment below a first threshold, thereby reducing leaching of the ligand into the fluid. Also described herein is an adsorbent comprising a ligand that is attached to a substrate by an amine bond, wherein the ligand is resistant to dissociation from the substrate.
US11458232B2 Medical fluid delivery system including remote machine updating and control
A medical fluid delivery system including remote machine updating and control is disclosed. An example medical fluid delivery system includes a medical fluid delivery device for a patient. The medical fluid delivery system also includes a server in communication with the medical fluid delivery device and a software application for a mobile device. The software application causes an icon to be displayed representing the medical fluid delivery device. The medical fluid delivery system further includes a first communication link between the medical fluid delivery device and the server, and a second communication link between the server and the software application. The software application receives status updates from the medical fluid delivery device via the server and the first and second links.
US11458230B2 Method comprising contacting tissue with a cross-linkable polyester prepolymer
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.
US11458229B2 Viscoelastic composition
The purpose of the present invention is to provide a viscoelastic composition having excellent operability, which is suitable for use in securing the field of view of an endoscope when opaque dark-colored liquid accumulates inside a canal and obstructs the field of view of the endoscope, the viscoelastic composition securing the field of view by pushing the liquid aside, and to provide a method for securing the field of view of an endoscope using the viscoelastic composition. The viscoelastic composition for securing the field of view of an endoscope comprises a substance having viscoelastic properties and water, preferably has a hardness of 550 N/m2 or less, a viscosity (25° C.) of 200 to 2,000 mPa·s, and a loss tangent of 0.6 or less, and more preferably has an electrical conductivity of 250 μS/cm or less. The method for securing the field of view of an endoscope comprises feeding the viscoelastic composition from a proximal part of the endoscope, through a channel, into a distal part of the endoscope.
US11458228B2 Monolithic composite orthopedic implants and associated methods
Implementations described herein provide for functionless monolithic composite implants and methods for manufacturing the same. The implant includes a monolithic composite body having a first region comprising a first metal alloy, a second region comprising a second metal alloy, and a transition region disposed between the first region and the second region formed from a bonded mixture of the first alloy and the second alloy. In one example, the transition region is a sintered mixture of the first alloy and the second alloy. In another example, the transition region is disposed at a region of minimum stress within the monolithic composite body under physiological loading conditions of the implant.
US11458223B2 Discharge device and electric machine
Provided is a discharge device that can improve the efficiency of generating reactive species. The discharge device includes a discharging unit, which has a tip end and discharges from the tip end in response to an application of a voltage, an induction electrode, which forms an electric field between the induction electrode end the discharging unit, and a second electrode, which is disposed between the discharging unit and the induction electrode and receives a voltage having a polarity the same as a polarity of the voltage applied to the discharging unit.
US11458222B2 Articles formed of pulp base materials with modulated scent release
Described are articles formed of a pulp base material comprising fibers, wherein pores are formed between the fibers. A volatile composition with at least one top note component and at least one base note component at least partially fills the pores of the pulp base material. A release rate of the at least one top note component is modulated by the pulp base material, and a release rate of the at least one base note component is enhanced by the pulp base material.
US11458221B2 Diatom microbubbler for biofilm removal
Diatom microbubblers comprising diatom biosilica or other silica linked to a catalyst for the decomposition of hydrogen peroxide, such as manganese oxide (MnO2), platinum (Pt), CuO (copper II oxide), or zinc peroxide (ZnO2) particles or nanosheets, or catalase are provided. Further provided are methods of reducing or eliminating biofilm or biofouling conditions.
US11458220B2 Microbial disinfection for personal protection equipment
A photosensitizer formulation can be disposed on or in a mesh; net; netting; screen; curtain of strands, fibers, or monofilaments; substrate, personal protective gear, mask, or any other suitable object. The photosensitizer formulation, when in contact with molecular oxygen and activated by light or ultrasound, produces microbicidal singlet oxygen. A variety of different arrangements and applications are described. For example, an air flow device may also be included to generate a flow of air through or over the photosensitizer formulation. A fluorescent formulation may be included to monitor photobleaching. The photosensitizer formulation may be disposed in a concentration gradient to generate antigenic particles by damaging or destroying microbes.
US11458215B1 Wearable sanitizing dispenser
A device for wearing on a person's wrist and dispensing a liquid, such as sanitizing liquid, includes a wristband that has a central mount and two opposing ends. Each end has one part of a two-part mechanical fastener. A container is fixed with the central mount of the wristband and has a top side, a side wall, and a bottom side. The side wall includes an open portion that is fixed with a nozzle. The top side includes a resilient pump diaphragm. The top side, side wall, and bottom side all define an internal volume within the container. Preferably the bottom side of the container includes a removable cap that is removable form the container to provide access to the internal space for refilling the container with the liquid. Depressing the pump diaphragm forces the liquid to be dispensed out of the nozzle.
US11458209B2 Compositions and methods for delivery of nucleic acid-lipid nanoparticle complexes encoding for viral RNA polymerase region and protein antigen
The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. Compositions of the disclosure include nucleic-acid lipid nanoparticle complexes encoding for viral RNA polymerase region and protein antigen. The nanoemulsion compositions of the disclosure comprises a hydrophobic core, optionally including inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided, including methods for administering to a subject a composition of the disclosure in an amount sufficient to generate an immune response.
US11458208B2 Desmoglein 2 antibody fusion proteins for drug delivery
The invention relates to antibody fusion proteins. Particularly, the invention relates to antibody fusion proteins for intra-cellular and intra-nucleus drugs delivery. The fusion protein of the invention can be used as a peptide penetration system that specifically binds to various targets for the delivery of effector peptides across a biological barrier.
US11458203B2 Pharmaceutical compositions comprising caffeic acid chelates
The present disclosure relates to pharmaceutical compositions comprising caffeic acid chelates, kits, and methods for using such compounds and pharmaceutical compositions.
US11458197B2 AipA, OmpA, and Asp14 in vaccine compositions and diagnostic targets for Anaplasma phagocytophilum infection
Anaplasma phagocytophilum surface protein AipA and/or fragments thereof which comprise an invasin domain are used in compositions suitable to elicit an immune response to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. AipA proteins and protein fragments or antibodies directed to AipA proteins and protein fragments are also used in diagnostic assays to detect exposure to and/or infection with Anaplasmatacaea. AipA and/or fragments thereof are also used for these purposes in combination with one or both of Asp14 and OmpA proteins and/or fragments thereof which comprise an invasin domain. Homologs of these proteins are also used in the compositions and assays.
US11458196B2 Composition, preparation method and evaluation of a complex immunogen named I-SPGA for production of immunological active proteins (IAP)
The present invention relates to the composition and method of preparing an immunogen designated as I-spga consisting of a complex antigen prepared from 18 to 26 species of pathogenic microorganisms isolated from patients, inactivated with binary ethyleneamine (BEI) and formalin, diluted in a SPGA immunopotentiator mixed with QS-21 adjuvant. By inoculating the hens with the I-spga immunogen, hyperimmune eggs (Immunospga) are obtained which contain immunologically active proteins specific to the 18-26 antigens used for immunization. The immune response of the hens is specific to the used antigens by amplification of the antigenic signal by the SPGA immunopotentiator and due to a special immunization program that allows the immune system to act complex and intense: The I-spga complex antigen contains 18-26 microorganisms isolated from patients, bacterial bodies, components from bodies obtained by ultrasonography, cilia, exotoxins, endotoxins, spores, viruses, fungi or yeasts. This pathogenic material is inactivated with BEI and formalin. The I-spga antigen is of three types. The standard I-spga antigen is composed of 18 to 24 antibiotic-resistant bacterial species isolated from patients in Romania. The specific I-spga complex antigen is composed of the I-spga complex antigen containing a mixture of 7-9 strains from a single species of bacteria, fungi or yeasts isolated from patients in Romania mixed with SPGA and QS-21, used for inoculation of hens previously immunized with standard I-spga antigen. The personalized I-spga antigen is composed of patient-derived pathological material containing cellular debris and pathogenic germs inactivated with BEI and formalin and mixed with SPGA and QS-21 and is used to immunize hens previously immunized with the standard I-spga antigen. This now patented technology encompasses a new generation of biological products in which the immune response of the hens to different groups of parenterally inoculated antigens at different time intervals is overlapping. Chicken response is uniform and additional administration of immunogens and SPGA as an immunopotentiator amplifies the antigenic signal and immune response. The I-spga immunogen as well as the immune response contain two markers, G and A, which identify the I-spga antigen used for immunization against the antigens used to produce the Imunoinstant group bio-preparations or similar products. The I-spga immunogen is used to immunize the hens for obtaining immunologically active proteins that can be used to treat immune deficiencies, psoriasis, epidermolysis bullosa, other dermatitises, nosocomial infections, antibiotic-resistant infections in the urinary system of children and grownups.
US11458189B2 Cytoprotective drugs
The invention relates to compounds of the echinocandin family or a semi-synthetic derivative thereof or a salt thereof or an ester thereof, or an ester salt thereof, intended to be used as a cytoprotective drug, particularly as a drug for the prevention and/or protection and/or treatment of cell death and/or of degenerative pathological situations or processes which result in cell death, and even more particularly as a drug for the prevention and/or protection and/or treatment of cell death and/or degenerative pathological situations or processes which result in cell death, when they are associated with ischaemia-reperfusion.
US11458188B2 ABC transporter peptide inhibitor XH-14C and application thereof
Provided are an ABC transporter peptide inhibitor XH-14C and an application thereof in the treatment of a tumor with multidrug resistance mediated by an ABC transporter. In the application, the peptide inhibitor XH-14C shown in SEQ ID NO: 1 is administered in combination with an ABC transporter substrate chemotherapeutic drug. This disclosure also provides a pharmaceutical composition for treating a tumor with multidrug resistance mediated by the ABC transporter, containing the peptide XH-14C shown in SEQ ID NO: 1 and an ABC transporter substrate chemotherapeutic drug.
US11458184B2 Compositions and methods for treating skin conditions, acne form lesions, and acne
A topically administered synergistic composition for treating skin conditions, acne form lesions, and acne that simultaneously downregulates the production of TNF alpha, IL-1a, IL-8, Leptin, and Sebum in human skin as well as inhibiting bacterial biofilm growth on human skin as well as inhibition and/or prevention of inflammation in the pilosebaceous unit and/or hair follicle of human skin.
US11458177B2 Enterococcus faecium bacteriophage Ent-FAP-4 and use for inhibiting Enterococcus faecium proliferation of same
The present invention relates to Siphoviridae bacteriophage Ent-FAP-4 (accession number KCTC 12854BP), separated from nature, which is capable of specifically killing Enterococcus faecium and has a genome expressed by sequence number 1, a pharmaceutical composition, which comprises same as an active ingredient, and a method for preventing or treating diseases, induced by Enterococcus faecium, by administering the pharmaceutical composition.
US11458176B2 Composition for use in the treatment and/or improvement of sleep and mood disorders
The present invention refers to a composition for use in the treatment of sleep disorder, in particular, in the improvement of sleep quality. Furthermore, the present invention refers to a composition for use in the treatment of mood modulation.
US11458173B2 Synergistic bacterial compositions and methods of production and use thereof
Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
US11458172B2 Nucleic acid systems that enable bacteria to specifically target solid tumors via glucose-dependent viability
Provided is a nucleic acid system introduced into a bacterial strain to generate a genetically engineered bacterial strain that grows in solid tumors but does not grow in non-tumor tissues, the nucleic acid system comprising: a first DNA fragment that encodes a toxin gene that expresses a toxin that kills the genetically engineered bacterial strain; a second DNA fragment that encodes an antidote gene that expresses an antidote that negates the toxin; a first promotor that controls transcription of the antidote gene, such that glucose represses the transcription of the antidote gene; and a first constitutive promoter that causes constitutive expression of the toxin gene; wherein the second DNA fragment is transcribed in the solid tumors but not transcribed in the non-tumor tissues.
US11458170B2 Pharmaceutical composition comprising erythrocytes encapsulating a PLP-dependent enzyme and, a non-phosphate PLP precursor
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine beta-synthase.
US11458169B2 TIM3-binding chimeric antigen receptors
Disclosed herein are chimeric antigen receptor (CAR) polypeptides that can be used with adoptive cell transfer to target and kill TIM3-expressing cancers. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with a TIM3-expressing cancer that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
US11458163B2 Platinum(IV) conjugates and methods of use
Provided are platinum(IV) compounds of Formula I or pharmaceutically acceptable salts thereof. Also provided are compositions including such compounds as well as methods of using the same.
US11458158B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof
Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R′, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.
US11458157B2 Compositions and methods for modifying a predetermined target nucleic acid sequence
Provided herein are compositions and methods for modifying a predetermined nucleic acid sequence. A programmable nucleoprotein molecular complex containing a polypeptide moiety and a specificity conferring nucleic acid (SCNA) which assembles in-vivo, in a target cell, and is capable of interacting with the predetermined target nucleic acid sequence is provided. The programmable nucleoprotein molecular complex is capable of specifically modifying and/or editing a target site within the target nucleic acid sequence and/or modifying the function of the target nucleic acid sequence.
US11458156B2 Compositions comprising circular polyribonucleotides and uses thereof
This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof.
US11458155B1 Active ingredient complexes, compositions and methods for hangover relief and to ameliorate alcohol-induced liver damage
An active ingredient complex is effective to treat, reduce the likelihood of developing, reduce the severity of, or ameliorate acute alcoholic liver damage or the symptoms of a hangover. In some embodiments, the active ingredient complex includes NADH (nicotinamide adenine dinucleotide (NAD)+hydrogen (H)), L-cysteine, dihydromyricetin (DHM), N-acetyl-cysteine (NAC), L-theanine, and buffered vitamin C, or pharmaceutically acceptable salts or derivative thereof. According to some embodiments, a pharmaceutical composition or dietary supplement may include the active ingredient complex and one or more pharmaceutically acceptable carriers, excipients, adjuvants and/or diluents.
US11458153B2 Drug delivery composition comprising a self-assembled gelator
This invention discloses drug-delivery compositions, methods of making prodrugs, and methods of drug delivery using a self-assembled gelator. The backbone of the gelator can contain a drug or prodrug, such as acetaminophen or salicin. Additional drugs or agents can be encapsulated in the gelator. Enzymatic or hydrolytic cleavage can be used to release the drugs.
US11458148B2 Method and compositions for the treatment of anemia through the inhibition of furin
Methods and compositions that can be used to modulate the activity of furin in a subject are disclosed herein. In some embodiments, the methods include administering a pharmaceutical composition including a protease inhibitor. In some embodiments, the protease inhibitor inhibits furin activity by binding to the catalytic site, the allosteric site, or both.
US11458146B2 Compositions and methods for the treatment of myelin related and inflammation related diseases or disorders
Described are oxysterols, pharmaceutical compositions including the oxysterols, and methods of using the oxysterols and compositions for treating diseases and/or disorders related to inflammation, such as necrotizing enterocolitis, mesenteric ischemia, inflammatory bowel diseases including Crohn's disease and ulcerative colitis, lymphocytic colitis, Celiac disease. Behcet's disease, rheumatoid arthritis, psoriasis, and autoimmune thyroid disease.
US11458140B2 Annulated glycosidase inhibitors
Compounds of formula (I), wherein A, R, W1, W2, W3, W4, W5, W6, L, Q, Rx and u have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
US11458139B2 Use of BRAF inhibitors for treating cutaneous reactions caused by treatment with a MEK inhibitor
The present technology relates to compositions comprising BRAF inhibitors and uses thereof for treating and/or preventing a MEK inhibitor-associated cutaneous condition in a subject. Kits for use in practicing the methods are also provided.
US11458134B2 1-[2-(2,4-dimeihylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
US11458133B2 Methods for solid tumor treatment
Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
US11458132B2 Quinolin-2(1H)-one inhibitors of Late SV40 Factor
The present invention is directed to compositions, methods and kits for treatment of cancer, e.g., hepatocellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I) to inhibit tubulin acetylation, to inhibit cell migration, or to modulate cell compaction.
US11458129B2 Neurokinin antagonists and uses thereof
In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described.
US11458126B2 DHODH inhibitor for use in treating hematologic cancers
A method of use for Cpd 1 as an inhibitor of dihydroorotate dehydrogenase (DHODH) function in treating or ameliorating a hematological cancer in a subject in need thereof comprising, administering an effective amount of Cpd 1 to the subject, having the structure: or a form or pharmaceutical composition thereof.
US11458124B2 Spirocyclic indane analogues as IL-17 modulators
A series of substituted spirocyclic indane derivatives of Formula (I), and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.
US11458119B2 Amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.
US11458116B2 Method of improving sleep
The invention provides methods of improving sleep in a patient having a variant of the cryptochrome circadian clock 1 (CRY 1) genotype associated with a circadian rhythm sleep disorder (CRSD) Delayed Sleep Wake Phase Disorder (DSWPD).
US11458115B2 Method for treatment of Parkinson's disease
Disclosed is a method for the treatment of a neurological or movement disorder, e.g., Parkinson's disease, in an individual in need thereof, by parenteral administration of levodopa and a dopa decarboxylase inhibitor (DDCI), such as carbidopa, benserazide or any combination thereof, concomitantly with oral administration of levodopa, a DDCI, such as carbidopa, benserazide, or any combination thereof.
US11458114B2 Methods and compositions for enhancing synthesis secretion and transport of collagen to increase wound strength
A method for, and medicinal composition for, treatment of mammalian cells for enhancing synthesis, secretion and transport of collagen to increase wound strength, that includes magnesium pyruvate; calcium pyruvate; L proline; citrulline: and a liquid carrier.
US11458111B2 Ketogenic diet compatible fenfluramine formulation
A method of treating symptoms of a subtype of epilepsy, e.g., Dravet syndrome, in a patient diagnosed with a subtype of epilepsy, by administering to the patient an effective dose of a fenfluramine formulation in combination with a ketogenic diet over a period of time sufficient to reduce or completely eliminate seizures in the patient. Also provided are compositions and kits finding use in practicing embodiments of the methods.
US11458110B2 Treatment of Fragile X Syndrome with cannabidiol
The present technology relates to a method of treating one or more behavioral symptoms of Fragile X Syndrome in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of Fragile X Syndrome are treated in the subject.
US11458108B2 Topical pharmaceutical compositions
The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
US11458107B2 Abiotic anti-VEGF nanoparticle
The present invention relates generally to compositions and methods comprising abiotic, synthetic polymers with affinity and specificity to proteins. The synthetic polymers are an improvement over biological agents by providing a simpler, less expensive, and customizable platform for binding to proteins. In one embodiment, the compositions and methods relate to synthetic polymers with affinity and specificity to vascular endothelial growth factor (VEGF). In one embodiment, the compositions are useful for treating diseases and disorders related to the overexpression of VEGF. In one embodiment, the compositions are useful for treating cancer. In one embodiment, the compositions are useful for detecting VEGF levels from biological samples. In one embodiment, the compositions are useful for detecting overexpression of VEGF from biological samples. In one embodiment, the compositions are used to diagnose cancer.
US11458106B2 Lipid nanoparticles comprising lipophilic anti-inflammatory agents and methods of use thereof
The immunostimulatory effect of lipid nanoparticles (LNPs) continues to block their use for safe and effective delivery of pharmaceutical drugs. Consequently, there exists a need to develop effective LNP delivery systems with an increased therapeutic window that do not trigger an inflammatory response. Disclosed herein are lipid nanoparticles comprising a lipid phase and at least one lipophilic anti-inflammatory agent, and pharmaceutical compositions comprising lipid nanoparticles and methods for using lipid nanoparticles. The anti-inflammatory lipid nanoparticles disclosed herein may further serve as platforms for selective delivery of, for example, nucleic acid segments to target cells and tissues, such as antisense oligonucleotides, DNA, mRNAs, siRNAs, Cas9-guideRNA complex.
US11458103B2 Delayed release deferiprone tablets and methods of using the same
The invention is directed to pharmaceutical compositions such as tablets that exhibit delayed release properties when administered as either whole or half tablets. The invention is also directed to delayed release tablets comprising deferiprone for oral administration, for which twice daily administration is bioequivalent to the same daily dose of an immediate release tablet administered thrice daily. The invention is also directed to methods of making and using the same.
US11458098B2 Dry powder compositions of treprostinil prodrugs and methods of use thereof
The present disclosure provides a dry powder composition of treprostinil prodrugs and a method of treating pulmonary hypertension (e.g., pulmonary arterial hypertension), portopulmonary hypertension, or pulmonary fibrosis in a patient in need thereof. The dry powder composition includes (a) from about 0.1 wt % to about 3 wt % of a compound of Formula (I): or an enantiomer, diastereomer, or a pharmaceutically acceptable salt thereof, (b) from about 0.01 wt % to about 3 wt % of DSPE-PEG2000, (c) from about 10 wt % to about 50 wt % of leucine, and the balance being (d) a sugar selected from the group consisting of trehalose and mannitol. The entirety of (a), (b), (c), and (d) is 100 wt %, and R1 is tetradecyl, pentadecyl, hexadecyl, heptadecyl, or octadecyl. The method includes administering an effective amount of the dry powder composition to the lungs of the patient by inhalation via a dry powder inhaler. In certain compositions and methods provided herein, R1 is hexadecyl, e.g., linear hexadecyl.
US11458095B2 Pharmaceutical solution of amlodipine
Disclosed herein is a liquid pharmaceutical formulation substantially free of water, comprising: (i) amlodipine or a pharmaceutically acceptable salt thereof, (ii) at least one pharmaceutically acceptable excipient, and (iii) a sufficient amount of a vehicle comprising glycerin. Also disclosed herein is a liquid pharmaceutical formulation substantially free of water and ethanol, comprising: (i) amlodipine or a pharmaceutically acceptable salt thereof, (ii) at least one pharmaceutically acceptable excipient, and (iii) a sufficient amount of a vehicle comprising glycerin.
US11458092B2 Composition with enhanced passenger molecule loading
A composition comprising surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein is disclosed, wherein one or more surfactant is utilized for enhancing loading and increasing encapsulation efficiency of cannabinoid passenger molecules within phospholipid structures. A method is disclosed for making a surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein, wherein one or more surfactant is used for enhancing loading and increasing encapsulation efficiency of passenger molecules in phospholipid structures. A method of using surfactant-enhanced phospholipid vesicles with one or more cannabinoid substance encapsulated therein is disclosed wherein one or more surfactant enhances loading and increases encapsulation efficiency of cannabinoid substances in phospholipid structures. A composition and method of making surfactant-enhanced phospholipid vesicles with one or more lipophilic passenger substance encapsulated therein is disclosed wherein one or more surfactant is utilized for enhancing loading and increasing encapsulation efficiency of passenger molecules within phospholipid structures.
US11458091B2 Compositions and methods for the treatment of opioid overdose
Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising nalmefene are provided. Methods of treating opioid overdose with the drug products are also provided.
US11458090B2 SPF-enhanced water-releasing sunscreen composition
A sunscreen composition includes a silicone phase that includes at least one silicone film former, a blend of silicones that includes at least one of each of a low viscosity silicone fluid, a silicone co-emulsifier and a self-emulsifying silicone elastomer. The composition includes a UV filter system that includes one or more UV filters. The silicone film former and blend of silicones are present in quantities sufficient to provide an SPF that is boosted by at least 100% as compared to a composition that lacks silicone film former, and the cosmetic composition has a unique texture that provides low friction and high glide.
US11458088B2 Cosmetic molded article and method for manufacturing same
The present invention provides a cosmetic shaped product: which is substantially formed with relatively low-molecular-weight hyaluronic acid or a water-soluble salt thereof having a high penetrability into the skin; which is easily soluble to water; and which has satisfactory handling properties, and a method for producing the cosmetic shaped product. There is provided a cosmetic shaped product being a sponge-like shaped body formed with at least one polyanionic polysaccharide of hyaluronic acid and a water-soluble salt thereof each having an average molecular weight of 30,000 or lower, the sponge-like shaped body having a bulk specific gravity of 5 to 500 mg/mL. This cosmetic shaped product can be produced by freeze-drying an aqueous solution having a content of the polyanionic polysaccharide of 0.5 to 30% by mass.
US11458087B2 Method of isolating cannabidiol from Cannabis plant and use thereof
Provided are a method of preparing a cannabis processed product having an increased CBD content in an efficient and economic manner, through decarboxylic acid reaction by microwave irradiation of cannabis using various extraction solvents, and use of the processed product having an increased CBD content prepared by the method, a fraction thereof, and a single ingredient of CBD, in foods, drugs, and cosmetics.
US11458083B2 Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities
The present invention relates to a cosmetic and/or dermatological composition comprising in a physiologically acceptable medium at least one merocyanine derivative of formula (1) or (2) and/or its E,E-, E,Z- or Z,Z-geometrical isomer forms: comprising specific polar groups consisting of hydroxyl- and ether-functionalities. Another object of the present invention relates to a cosmetic process for controlling and/or improving the darkening of the skin under exposure to UV radiation and the homogeneity of the colour of the complexion which comprises the application onto the skin of a cosmetic composition as above defined. Another object of the present invention relates to a cosmetic process for protecting the keratinic materials and particularly the skin against photo-ageing which comprises the application onto the keratinic material of a cosmetic composition as above defined.
US11458082B1 Tanning compositions including dihydroxyacetone
Embodiments disclosed relate to self-tanning compositions that include at least 0.1 weight percent dihydroxyacetone and at least 1 weight percent water in an internal phase in addition to an external phase formulated to provide a solid body, and the self-tanning composition is stable at ambient temperatures.
US11458081B2 Personal care compositions
Described herein are low pH, high water, personal care compositions providing an acceptable level of micropreservation. Methods of making and using these compositions are also described.
US11458077B2 Two-phase cosmetic composition comprising a 4-(3-alkoxy-4-hydroxyphenyl)alkyl ketone
The invention relates to a composition comprising an aqueous phase and an oily phase which are visually separate and superimposed, 1,3-propanediol and a ketone compound of formula (I): wherein R1 is a C2-C4 alkyl radical; R2 is H or a C1-C4 hydrocarbon-based radical; R3 is a C1-C4 hydrocarbon-based radical; and C—X is C═O. The invention can be used for the cosmetic treatment of keratin materials.
US11458076B2 Dental composite material with adapted ratio of flexural strength to elastic modulus, and mill blanks made of said composite material
A polymerisable dental composite material comprising (i) 60 to 85% by weight of an inorganic filler component comprising at least one tectosilicate and optionally at least one dental glass and/or at least one amorphous metal oxide, (ii) 10 to 40% by weight of a mixture of at least two different urethane(meth)acrylates, (iii) 0.01 to 5% by weight of at least one di-, tri-, tetra- or multi-functional monomer not being a urethane(meth)acrylate, (iv) 0.01 to 10% by weight of at least one initiator, an initiator system and optionally at least one stabiliser and optionally at least one pigment, wherein the total composition of the composite material amounts to 100% by weight, and a polymerised composite material having a flexural strength of greater than or equal to 240 MPa and an elastic modulus of 16 to 20 GPa for the production of indirect dentures.
US11458073B1 Smart bottle system and methods thereof
This invention relates to smart bottle system that informs the user through a display, the time and date that the contents are to be taken. More specifically, the smart bottle system provides an information to the user/patient, the time to take medication and inform the caregiver, physician, pharmacy personnel, or patient/users of missed doses, the profile, and/or the health condition of the patient/user. The bottle system may track the dosses remaining in the bottle, and inform the caregiver or patient/user, or pharmacy personnel the time to get a refill of the medication. The system can able to compute the profile and/or health condition of the users, based on the medication intake, and/or missed, or users image, and can communicate with the persons located remotely by sending/receiving information.
US11458071B2 Torque enhancer device for grasping and tooling, and assemblies and uses thereof
A torque enhancement device having one or more torque enhancement member(s) with each having an exterior (preferably bi-symmetric or essentially bi-symmetric) surface configuration with parallel, longer side walls extending in a Y-axis direction and shorter side walls extending in an X-axis direction and corner recesses positioned between ends of adjacent longer and shorter side walls, and with some embodiments of the invention featuring a torque enhancement device having a hole extending in a Z-axis direction. A fastener assembly is also provided that includes one or more torque enhancement devices as well as methods for utilization of the torque enhancement device or utilization or assemblage of an assembly including a torque enhancement device. The surface configuration includes arrangements where there is a torque differential in one direction or the other as well as arrangements that are adapted to handle both standard fastener configurations and torque enhancement configurations with a common torque enhancement device.
US11458068B2 Apparatus and method for promoting shallow breathing of a patient
An apparatus for promoting shallow breathing of a patient includes a paddle, a belt, and a bladder. The paddle may be configured to contact the body of the patient. The belt may be configured to secure the paddle against the body of the patient. Finally, the bladder may be interposed between the belt and the paddle in the installed condition, such that inflating the bladder urges the paddle toward the body of the patient so as to apply pressure to the abdomen of the patient. A method of promoting shallow breathing is also provided that includes attaching a paddle and a bladder to a belt, such that the bladder is between the paddle and the belt, positioning the paddle on the patient, and inflating the bladder to urge the paddle toward the body of the patient such that the paddle applies pressure to the abdomen of the patient.
US11458067B2 Soft portable wearable pneumatic interactive suit
A fully wearable system used for communication and information transfer between two users or between a user and a machine to render an effective and intuitive physical interface for combined input and output functions, the fully wearable system including a bidirectional wearable skin including distributed actuator and sensing elements, the actuator and sensing elements including a multimodal actuation layer and a sensing layer, the bidirectional wearable skin being flexible and stretchable, and a portable control device for controlling the distributed actuator and sensing elements, and reading signals from the sensing layer, the portable control device is configured to perform pixilated actuation for both micro- and macrostimulation of a body of a wearer by an actuation frequency and stimulation amplitude.
US11458062B2 Motion stabilizing device for a cosmetic applicator
An apparatus is provided that stabilizes an applicator in response to the motion caused by a user, comprising: a receiver configured to be coupled with a cosmetic applicator; at least one sensor configured to detect a movement caused by a user; circuitry configured to determine a compensation movement to offset the detected movement; and at least one motion generation device embedded in the receiver configured to control a motion of the cosmetic applicator according to the determined compensation movement.
US11458061B1 Control of multiple joints of an upper body support system
Methods and system to partially support the weight of a human user engaged in task performance at ground level are presented herein. An upper body support system includes multiple degrees of freedom to adapt the physical geometry of the support system to meet the demands of the task at hand. Each degree of freedom of the upper body support system is passively controlled by the human user from a convenient user interface. In some embodiments, each end-effector of the support system is positioned and fixed in three degrees of freedom over a relatively large workspace by manually controlling the brake torque of two rotational joints and the state of a locking mechanism of a linear joint. In another aspect, an end-effector is removeably attached to the support system with a quick-change coupler. In some embodiments, a swivel joint mechanism compensates for misalignment with the work environment.
US11458060B2 Reclinable therapeutic massage chair
A therapeutic massage chair is reclinable between a horizontal and an inclined position. The chair includes an upper back support member and a lower support member that is axially movable along a support frame, and is also rotatable about an axis which is perpendicular to the plane of the upper back support member. Electric linear actuators are provided to both axially move and oscillate the lower body support member.
US11458059B2 Cremation vessel and display
A web connected ornamental funerary apparatus is controlled over a data network comprised of (1) a microprocessor and network connectivity for device and remote sound, image projection, communication and actuation, (2) a cremains repository that serves as (a) an ornament platform, (b) apparatus base, and (c) housing for microelectronic elements, (3) a cap which serves to (a) isolate and protect the cremains, (b) house micro circuitry, and (c) secure a physical hyaloid ornament sculpture and/or project light or a holographic image above the cap, (4) a locking mechanism, and (5) an ornamental feature situated above the repository.
US11458058B2 Support system for mounting a medical device
A support system for mounting a medical-technical device, comprises a fixation unit, a support module that is attachable to fixation unit, a support arm that comprises a mounting end and an attachment end, wherein the mounting end is mountable to support module; and a joint member that is attachable to attachment end of support arm.
US11458055B2 Mobility device for assisting a patient
A mobility device for assisting a patient includes a frame having a wheel arranged to maneuver the mobility device; a lift assembly coupled to the frame and movable between a lowered position and a raised position; and a support arm coupled to the lift assembly for movement with the lift assembly and arranged to support an upper part of a body of the patient and to support at least part of his weight on the mobility device when the lift assembly is raised from the lowered position to the raised position and when maneuvering the mobility device.
US11458052B2 Skin injury resistant occupant support structures and methods for resisting skin injuries
An occupant support structure for supporting an occupant includes an orientation adjustable torso section, a lower body section, and a control system. The lower body section includes a heel region subsection which supports the heel region of an occupant of the occupant support. The control system is adapted to A) cause the heel region subsection to temporarily substantially disengage from the heel region of the occupant in response to a change of angular orientation of the torso section which begins at a time t0, and B) cause the heel region subsection to subsequently re-engage with the heel region of the occupant, the re-engagement occurring at a time tB which is later than t0.
US11458049B2 Absorbent articles including perfume and cyclodextrins
An absorbent article comprising a perfume which is suitable for improved release from a cyclodextrin complex, wherein the perfume includes 10% or more, by weight of the perfume, of one or more perfume raw materials having: a cyclodextrin complex stability constant (log k) of less than about 3.0, a ClogP of about 2.5 or less, and a weight average molecular weight of about 200 Daltons or less.
US11458048B1 Closable sanitary napkin system
A closable sanitary napkin system that is secured once rolled or closed by flaps attached towards one end. The flaps remain in contact with the bottom of the napkin until the time of disposal when they are pulled out and used to secure the napkin closed. The napkin could also have a pattern or image printed on the bottom surface to obscure any contents of the napkin.
US11458046B2 Chassis design for absorbent article
A disposable absorbent article may include a first waist region, a second waist region, a crotch region disposed between the first and the second waist regions, and a chassis having a topsheet, backsheet, absorbent core, and chassis periphery. The chassis periphery has a varying width, Wv.
US11458042B2 Bilayered devices for enhanced healing
Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process.
US11458036B2 Oral appliance apparatus and method of operation thereof
A device for treating sleep disorders such as snoring and sleep apnea comprising an upper portion, and a lower portion; wherein a first bottom surface of the upper portion, is joined to a second top surface of the lower portion using a sealant. A method of treating sleep disorders such as snoring and sleep apnea includes using an oral appliance, and a positive airway pressure machine for assisting a user to breathe through the nose.
关于PatentHub
关于我们 加入我们 联系我们 帮助中心
PatentHub产品
专利百科 商标查询 专利交易 大学排行榜 行业专题库
API接口 排行榜 专利资讯 最新中国发明专利 最新美国发明专利
PatentHub联系方式
QQ：3307693423 QQ：3236401158