最新美国发明专利第2022-08-23期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US11421361B2	Device for the production of nonwoven fabric webs and method for installing such a device A device for the production of nonwoven fabric webs. The device includes a nonwoven production device comprising a supporting structure, and an auxiliary unit comprising at least one liquid tank and a platform arranged on a top side of the auxiliary unit. The nonwoven production device is arranged on the supporting structure in an assembled state. The nonwoven production device and the auxiliary unit are arranged in relation to each other so that, for at least one of assembling, operating, and repairing the nonwoven production device, access to the nonwoven production device is provided from the platform.
US11421360B2	Fiber sheet and method for manufacturing same According to one embodiment, a fiber sheet includes a plurality of fibers. The plurality of fibers are in a closely-adhered state. All of the following (1) to (3) are satisfied, where F1 is a tensile strength in a first direction, and F2 is a tensile strength in a second direction orthogonal to the first direction: (1) F2>F1; (2) F1 is 1 MPa or more; and (3) F2/F1 is 2 or more.
US11421354B2	Flat knitting machine yarn feeder with variable yarn feeding positions A flat knitting machine yarn feeder with variable yarn feeding positions is provided. The flat knitting machine yarn feeder includes a driving mechanism and a yarn feeding mechanism. The driving mechanism is controlled by an electronic signal and includes a driving plate which makes a push stroke after started. The yarn feeding mechanism comprises a joining plate connected with the driving plate and a yarn feeding arm assembled with the joining plate. The joining plate comprises a guide hole. The yarn feeding arm comprises a guide column disposed in the guide hole. The joining plate makes a displacement stroke when the driving plate makes the push stroke. The guide column changes a position in the guide hole when the joining plate makes the displacement stroke. The yarn feeding arm changes a yarn feeding position when the guide column changes the position.
US11421352B2	Woven textile A woven textile defines a longitudinal direction and a transverse direction and includes a first layer, a second layer, and at least one binding thread. The first layer includes at least one first braid extending in a sinusoidal wave pattern. The second layer includes a plurality of rows of second braid extending along the transverse direction in a sinusoidal wave pattern. The rows of second braid are aligned along the longitudinal direction and are separated. Each of the rows of second braid is stacked with the at least one first braid to form a plurality of overlap portions. The at least one binding thread is woven with each of the rows of second braid and the at least one first braid together at the overlap portions to fix the row of second braid and the at least one first braid.
US11421348B2	Flame resistant fabrics having fibers containing energy absorbing and/or reflecting additives Embodiments of the invention relate to flame resistant fabrics containing fibers having at least one energy absorbing and/or reflecting additive incorporated into the fibers. Inclusion of such fibers into the fabric increases the arc rating/fabric weight ratio of the fabric while still complying with all requisite thermal protective requirements.
US11421346B2	Active cleaning vacuum system and method A vacuum system for silicon crystal growth includes a silicon crystal growth chamber, a first vacuum pipe, a second vacuum pipe, and an oxides container. The first vacuum pipe is coupled to the chamber and has within a first brush that is movable in a first direction for removing internal oxides. The second vacuum pipe is coupled to the first vacuum pipe for receiving the internal oxides via the first brush and has within a second brush that is movable in a second direction different from the first direction. The second brush transports the received internal oxides away from the first vacuum pipe. The oxides container is coupled to the second vacuum pipe for receiving the internal oxides via the second brush.
US11421343B2	Method and apparatus for producing bulk silicon carbide using a silicon carbide seed A method of producing silicon carbide is disclosed. The method comprises the steps of providing a sublimation furnace comprising a furnace shell, at least one heating element positioned outside the furnace shell, and a hot zone positioned inside the furnace shell surrounded by insulation. The hot zone comprises a crucible with a silicon carbide precursor positioned in the lower region and a silicon carbide seed positioned in the upper region. The hot zone is heated to sublimate the silicon carbide precursor, forming silicon carbide on the bottom surface of the silicon carbide seed. Also disclosed is the sublimation furnace to produce the silicon carbide as well as the resulting silicon carbide material.
US11421339B2	Method of manufacturing SiC single crystal and covering member A method of manufacturing a SiC single crystal includes: a storing step of storing a SiC source, which is a powder, in an inner bottom part of a crucible, wherein the crucible is configured to store the SiC source and to attach a seed crystal to a position of the crucible which faces the SiC source; a placing step of placing a porous material on at least a portion of a first surface of the SiC source, wherein the first surface is positioned on a side of the seed crystal; and a crystal growth step of sublimating the SiC source by heating to grow a crystal on the seed crystal, in which the porous material is formed of carbon or a carbide, and the hole diameter of the porous material is smaller than the average particle diameter of the SiC source.
US11421337B2	Electrolytic on-site generator Method and apparatus for a low maintenance, high reliability on-site electrolytic generator incorporating automatic cell monitoring for contaminant film buildup, as well as automatically removing or cleaning the contaminant film. This method and apparatus preferably does not require human intervention to clean. For high current density cells, cleaning is preferably performed by reversing the polarity of the electrodes and applying a lower current density to the electrodes, preferably by adjusting the salinity or brine concentration of the electrolyte while keeping the voltage constant. Electrolyte flow preferably comprises water and brine flows which are preferably separately monitored and automatically adjusted. For bipolar cells, flow between modules arranged in parallel is preferably approximately equally distributed between modules and between intermediate electrodes within each module.
US11421336B2	Systems and methods for electroplating sources for alpha spectroscopy Disclosed herein are a system and method for electroplating an alpha emitting radionuclide, such as an actinide, for use in alpha spectroscopy. The electrodeposition system for electroplating an alpha emitting radionuclide can include an electroplating cell containing a solution of an electrolyte and the alpha emitting radionuclide, a metal target within the electroplating cell, and a metal anode at a distance from the metal target. The system also includes a platform for supporting the electroplating cell, coupling mechanism connected to the platform, an electric motor on the elastic cushion, and a flywheel with an uneven weight distribution operatively connected to the electric motor. Rotation of the unevenly distributed flywheel generates a vibration in the electroplating cell which dislodges gas bubbles that have formed between the metal target and the metal anode.
US11421335B2	Electrolyte for the deposition of anthracite/black rhodium/ruthenium alloy layers The present invention is directed toward an electrolyte which allows for electrolytically producing a black metal layer consisting of rhodium and ruthenium. The present invention also relates to a method for producing a corresponding article, and to the use of the electrolyte.
US11421330B2	Methods for carbon dioxide hydrogenation A method of carbon dioxide hydrogenation comprises introducing gaseous water to a positive electrode of an electrolysis cell comprising the positive electrode, a negative electrode, and a proton-conducting membrane between the positive electrode and the negative electrode. The proton-conducting membrane comprises an electrolyte material having an ionic conductivity greater than or equal to about 10-2 S/cm at one or more temperatures within a range of from about 150° C. to about 650° C. Carbon dioxide is introduced to the negative electrode of the electrolysis cell. A potential difference is applied between the positive electrode and the negative electrode of the electrolysis cell to generate hydrogen ions from the gaseous water that diffuses through the proton-conducting membrane and hydrogenates the carbon dioxide at the negative electrode. A carbon dioxide hydrogenation system is also described.
US11421329B2	Hydrogen production system A hydrogen production system includes: a hydrogen production device connected to an electric power system and configured to produce hydrogen by electrolyzing pure water; an output control unit capable of controlling an amount of power supplied from the electric power system to the hydrogen production device according to request from the electric power system; a first pure water line for supplying pure water to the hydrogen production device; a first adjustment device capable of adjusting an amount of pure water supplied to the hydrogen production device via the first pure water line; and a first control unit configured to control the first adjustment device, based on a power amount signal indicating information on an amount of power supplied from the electric power system to the hydrogen production device.
US11421326B2	Hyperbranched polymers with active groups as efficient corrosion inhibitors In accordance with one or more embodiments of the present disclosure, a process for preventing corrosion of a metallic surface of a pipeline includes contacting the metallic surface with a corrosion inhibitor. The corrosion inhibitor comprises a polymer of formula R—O—(POL)-Z. R is a straight or branched alkyl or aryl; POL is a polyglycerol based polymer; Z is a non-ionic amine, a cyclic amine having 5 to 8 atoms, a diamine, a triamine, a tetra-amine, a polymeric amine, a thiol, a disulfide, or —NH—R1—SH; and R1 is a hydrocarbyl. The corrosion inhibitor is also disclosed.
US11421321B2	Apparatuses for thin film deposition In accordance with some embodiments herein, apparatuses for deposition of thin films are provided. In some embodiments, a plurality of stations is provided, in which each station provides a different reactant or combination of reactants. The stations can be in gas isolation from each other so as to minimize or prevent undesired chemical vapor deposition (CVD) and/or atomic layer deposition (ALD) reactions between the different reactants or combinations of reactants.
US11421320B2	Chemical delivery system and method of operating the chemical delivery system A chemical delivery system includes a bulk container, a run/refill chamber, a first conduit and a second conduit. The bulk container stores a precursor. The run/refill chamber includes a plurality of spaced tubes having a plurality of surfaces for receiving the precursor in vapor form and storing the precursor in solid form. The first conduit connects the bulk container to the run/refill chamber for transporting the precursor from the bulk container to the run/refill chamber in vapor form. The second conduit connects the run/refill chamber to a deposition chamber for transporting the precursor from the run/refill chamber to the deposition chamber in vapor form.
US11421315B2	Sputtering target and method of producing sputtering target [Object] To provide a sputtering target with further improved sputtering efficiency, and a method of producing the sputtering target.[Solving Means] In order to achieve the above-mentioned object, a sputtering target according to an embodiment of the present invention is a cobalt target having a sputtering surface and a purity of 99.95 wt % or more. An intensity ratio (I(002)+I(004))/(I(100)+I(002)+I(101)+I(102)+I(110)+I(103)+I(112)+I(004)) of X-ray diffraction peaks corresponding to a (100) plane, a (002) plane, a (101) plane, a (102) plane, a (110) plane, a (103) plane, a (112) plane, and a (004) plane of a hexagonal close-packed lattice structure along the sputtering surface is 0.85 or more.
US11421302B2	Free-cutting copper alloy and method for producing free-cutting copper alloy This free-cutting copper alloy comprises 76.0-78.7% Cu, 3.1-3.6% Si, 0.40-0.85% Sn, 0.05-0.14% P, and at least 0.005% to less than 0.020% Pb, with the remainder comprising Zn and inevitable impurities. The composition satisfies the following relations: 75.0≤f1=Cu+0.8×Si−7.5×Sn+P+0.5×Pb≤78.2; 60.0≤f2=Cu−4.8×Si−0.8×Sn−P+0.5×Pb≤61.5; and 0.09≤f3=P/Sn≤0.30. The area percentage (%) of respective constituent phases satisfies the following relations: 30≤κ≤65; 0≤γ≤2.0; 0≤β≤0.3; 0≤μ≤2.0; 96.5≤f4=α+κ; 99.4≤f5=α+κ+γ+μ; 0≤f6=γ+μ≤3.0; and 35≤f7=1.05×κ+6×γ1/2+0.5×μ≤70. κ phase is present in α phase, the long side of the γ phase is at most 50 μm, and the long side of the μ phase is at most 25 μm.
US11421297B2	Non-oriented electrical steel sheet A non-oriented electrical steel sheet includes a silicon steel sheet and an insulation coating. When t is a thickness of the silicon steel sheet and when PDR is defined as (PDR=(maximum−minimum)/minimum×100) which indicates a ratio concerned with maximum and minimum of number densities of AlN precipitates in three areas which are 1/10t area, ⅕t area, and ½t area from a surface of the silicon steel sheet along a thickness direction, the PDR is 50% or less.
US11421291B2	Process for local hardening A process for the local hardening of a workpiece by means of local induction hardening includes performing a local perlitization grain transformation on the workpiece after a local inductive diffusion heat treatment and before a local induction hardening on the workpiece.
US11421289B2	Method and apparatus for the production of cast iron, cast iron produced according to said method A method for the production of cast iron starting from pre-reduced iron ore (DRI) with an electric arc furnace includes the steps of preparing a charge of pre-reduced iron ore DRI having a metallization higher than 90% and containing over 2.8% by weight of carbon, wherein at least 80% of the carbon is combined with the iron to form iron carbide Fe3C; charging the charge of pre-reduced iron ore into the electric arc furnace; and melting the DRI charge to form liquid cast iron having at least 80% by weight of actual carbon content deriving from the carbon in the charge of pre-reduced iron ore, the melting step being in a reducing atmosphere and in a melting chamber of the electric arc furnace subjected to a positive internal pressure generated by the gases produced by reduction reactions that develop during melting.
US11421288B2	Ultra formed leather molding Leather and similar materials are formed using graduated molds. A solvent is applied to the leather to saturate the leather. The saturated leather is put through a series of molds, each being more pronounced than the previous. An elastomer is applied after molding to provide structural support for features created through molding.
US11421277B2	Methods and compositions for predicting chronic lung allograft dysfunction The present invention relates to a method for predicting the risk of having the CLAD in a subject by measuring the expression level of TCL1A in a biological sample obtained from said subject. Inventors have used a large-scale gene expression profiling of whole blood cells to identify early biomarkers of BOS. Microarray experiments performed from 80 patients (40 stable (STA) and 40 BOS) identified 47 genes differentially expressed between STA and BOS recipients. An independent set of patients (13 STA, 11 BOS) was then used for external validation by qPCR. T-cell leukemia/lymphoma protein 1A (TCL1A) gene was identified and validated as a predictive marker of BOS more than 6 months before diagnosis with area under curve of 0.77. Accordingly, the invention relates to a method for predicting the risk of having the chronic lung allograft dysfunction (CLAD) and to a method for preventing the risk of having CLAD by administering immunosuppressive drugs.
US11421273B2	In situ readout of DNA barcodes Disclosed herein include systems, methods, compositions, and kits for in situ readout of barcodes, such as DNA barcodes. Barcode constructs containing a promoter (e.g., a phage promoter) that is inactive in live cells can be integrated in the genomes of cells. Cells can be fixed, and phage RNA polymerase can be used for transcription of the barcode to RNA transcripts. The RNA transcripts can be detected using, for example, fluorescent imaging and used to determine barcode sequences.
US11421271B2	Methods and compositions for nucleic acid sequencing using photoswitchable labels Embodiments of the present disclosure relate to nucleotides labeled with photoswitchable compounds. Also provided herein are methods and kits of using these labeled nucleotides for sequencing applications.
US11421270B2	Screening of nucleic acid sequence variations via random loading of optically-encoded particles Embodiments disclosed herein provide reagents and methods for high-throughput screening of nucleic acid sequence variations in nucleic acid containing specimens. Nucleic acid specimens to be screened are loaded into separate discrete volumes. Optically encoded particles are used to deliver primers to amplify one or more sequences comprising the nucleic acid sequence variation. The optically encoded particles may be delivered to the discrete volumes randomly resulting in a random combination of optically encoded particles in each well, or a unique combination of optically encoded particles may be specifically assigned to each discrete volume. The observable combination of optically encoded particles may then be used to identify each discrete volume.
US11421269B2	Target enrichment by single probe primer extension The invention comprises methods and compositions for enriching for a target nucleic acid with a single primer extension and low-bias limited amplification.
US11421268B2	Methods and compositions for nucleic acid detection Methods, compositions, reaction mixtures, kits, and/or systems for producing a complementary sequence to a region in a target polynucleotide in a sample are provided. In some aspects, the methods, compositions, reaction mixtures, kits, and/or systems comprise subjecting the sample to a nucleic acid amplification reaction in a reaction mixture under conditions to yield the complete sequence to the region of the target polynucleotide. In some aspects, the complementary sequence produced is amplified.
US11421266B2	Set of oligonucleotide probes as well as methods and uses thereto The present disclosure relates to a set of at least 100 single-stranded oligonucleotide probes directed against (or complementary to) portions of a genomic target sequence of interest. The present disclosure also relates to a method of detecting a genomic target sequence of interest using the set of oligonucleotide probes and a method of generating the set of oligonucleotide probes. Further, the present disclosure relates to a kit comprising the set of oligonucleotide probes and at least one further component.
US11421262B2	Serial formation of ternary complex species A method for identifying a nucleotide in a primed template nucleic acid, including the steps of (a) providing a vessel having a primed template nucleic acid, polymerase and a nucleotide cognate of a first base type; (b) examining the vessel for a stabilized ternary complex including the polymerase and the nucleotide cognate of the first base type bound at a base position of the primed template nucleic acid; (c) delivering a nucleotide cognate of a second base type to the vessel, whereby the vessel retains the primed template nucleic acid and the polymerase from step (b); (d) examining the vessel for a stabilized ternary complex including the polymerase and the nucleotide cognate of the second base type bound at the base position of the primed template nucleic acid; and (e) identifying the type of nucleotide at the base position of the primed template nucleic acid.
US11421254B2	Biotechnological production of alcohols and derivatives thereof A method for oxidizing an alkyl, including a) contacting the alkyl with an aqueous solution comprising a microorganism where the microorganism has a reduced fatty acid degradation capacity compared to its wild type, wherein the fatty acid degradation capacity is reduced by deletion, inhibition or inactivation of a gene encoding an enzyme involved in the β-oxidation pathway; and the microorganism expresses a recombinant alkane oxidase, and b) contacting the aqueous solution from a) with a water-immiscible organic solvent.
US11421253B2	Engineered tyrosine ammonia lyase The present invention provides engineered tyrosine ammonia-lyase (TAL) polypeptides and compositions thereof. In some embodiments, the engineered TAL polypeptides have been optimized to provide enhanced catalytic activity and enhanced acid stability, while reducing sensitivity to proteolysis and increasing tolerance to acidic pH levels. The invention also provides methods for utilization of the compositions comprising the engineered TAL polypeptides for therapeutic and industrial purposes.
US11421251B2	Genome engineering with type I CRISPR systems in eukaryotic cells Disclosed herein are Type I Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) system related compositions and methods of using said Type I CRISPR/Cas system related compositions for altering gene expression and genome engineering. The invention relates to compositions comprising Type I CRISPR-Cas polypeptides and CRISPR array nucleic acids designed for genome modification in eukaryotic cells and for targeted killing of eukaryotic cells.
US11421246B2	Rust resistance gene The present invention relates to new transporter polypeptides, and genes encoding therefor, which can be used to confer upon a plant resistance to one or more biotrophic fungal pathogens.
US11421244B2	Nucleotide sequences and corresponding polypeptides conferring modulated growth rate and biomass in plants grown in saline conditions The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of improved plant size, vegetative growth, growth rate, seedling vigor and/or biomass in plants challenged with saline conditions. The present invention further relates to the use of these nucleic acid molecules and polypeptides in making transgenic plants, plant cells, plant materials or seeds of a plant having plant size, vegetative growth, growth rate, seedling vigor and/or biomass that are improved in saline conditions with respect to wild-type plants grown under similar conditions.
US11421242B2	Genes, constructs and maize event DP-202216-6 The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
US11421241B2	Method for conducting site-specific modification on entire plant via gene transient expression The present invention discloses a method for site-directed modification of whole plant through gene transient expression. The method as provided for conducting site-directed modification to a target fragment of a target gene in a whole plant comprises the following steps: transiently expressing a sequence-specific nuclease in said plant, wherein a whole plant is used as the subject for transient expression, said sequence-specific nuclease targets and cleaves said target fragment, thereby the site-directed modification is achieved via the self DNA repairing of said plant. In the present invention, tissue culture is omitted by transient expression of the sequence-specific nuclease; mutation is obtained at whole plant level; the method is independent of the genotype and recipient, and thus can be applied to various varieties of various species; T1 mutants can be obtained directly and the mutation can be stable inherited; more importantly, the mutant plant as obtained is free of exogenous genes, and thus have higher bio-safety.
US11421235B2	Methods and microorganisms for the fermentation of methane to multi-carbon compounds Genetically modified microorganisms that have the ability to convert carbon substrates into multicarbon products. Methods of making these genetically modified microorganisms and methods of using them. Vectors encoding enzymes for use in converting carbon substrates into multicarbon products.
US11421233B2	Methods relating to circulating tumor cell clusters and the treatment of cancer Described herein are methods and assays relating to the presence and/or level of circulating tumor cells (CTCs). These CTC-Cs represent a highly metastatic subpopulation of CTCs. In some embodiments, the methods and assays described herein relate to the treatment of cancer.
US11421229B2	p63 inactivation for the treatment of heart failure Embodiments of the disclosure include methods and compositions for in situ cardiac cell regeneration, including transdifferentiation of cardiac cells to cardiomyocytes. In particular embodiments, in situ cardiac cell regeneration encompasses delivery of p63 shRNA and one or both of Hand2 and myocardin, and in specific embodiments further includes one or more of Gata4, Mef2c, and Tbx5. In specific aspects of the disclosure, adult cardiac fibroblasts are reprogrammed into cardiomyocytes using viral vectors that harbor p63 shRNA and one or both of the transcription factors Hand2 and myocardin.
US11421227B2	Treating and preventing microbial infections The invention provides methods for treating or preventing microbial (eg, bacterial) infections and means for performing these methods. In particular, treatment of infections requiring rapid and durable therapy is made possible, such as for treating acute conditions such as septicemia, sepsis, SIRS or septic shock. The invention is particularly useful, for example, for treatment of microbes such as for environmental, food and beverage use. The invention relates inter alia to methods of controlling microbiologically influenced corrosion (MIC) or biofouling of a substrate or fluid in an industrial or domestic system. The invention also useful for the treatment of pathogenic bacterial infections in subjects receiving a treatment for a disease or condition, such as a transplant or a treatment for cancer, a viral infection or an autoimmune disease.
US11421226B2	Programmable artificial cell The present invention provides cell-free systems comprising: (i) a transcription compartment; (ii) a barrier; and (iii) a translation compartment, methods for producing proteins and performing post-translational modifications thereon using such systems, and kits comprising such systems.
US11421224B2	Microarray based multiplex pathogen analysis and uses thereof Provided herein is a method for manufacturing a 3-dimensional lattice microarray system for DNA sequence detection and analysis. A solid support is contacted with a formulation containing a plurality of nucleic acid probes, a plurality of bifunctional polymer liners and a solvent mixture of water and a water-miscible liquid. In a first attachment reaction the bifunctional polymer linkers are attached to the solid support and the water is evaporated. In a second attachment reaction the nucleic acid probes are attached to the bifunctional polymer linker.
US11421221B2	Combinatorial photo-controlled spatial sequencing and labeling Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers.
US11421220B2	Engineered cells expressing anti-viral T cell receptors and methods of use thereof Provided herein are compositions comprising recombinant mammalian cells that express recombinant T cell rectors with specificity against EBV or CMV peptide:MHC antigens. Also provided are therapeutic methods of using the recombinant mammalian cells as cell therapies against viral infections.
US11421219B2	Methods and compositions for treating Leber congenital amaurosis Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
US11421218B2	Methods for enhancing the efficiency of gene editing The present invention provides methods of increasing the efficiency of genome editing.
US11421217B1	Methods and compositions for collection and preservation of biologicals Provided herein are compositions and methods of use thereof for collection, preservation and/or extraction of biologicals from a subject. For example, a solution that enables collection, preservation, and extraction of nucleic acids in a single step, and methods of using such solution are provided. In some embodiments, the compositions, kits, and methods are useful for the collection and analysis of samples from patients that have or are suspected of having SARS-CoV-2 virus that can cause Covid-19.
US11421214B2	System based on a new nitrile hydratase for highly efficient catalytic hydration reaction of aliphatic dinitriles The invention belongs to the technical field of green chemistry, and provides a novel system based on a new nitrile hydratase for highly efficient catalytic conversion of aliphatic dinitriles. The invention discloses a new application of nitrile hydratase using Rhodococcus erythropolis CCM 2595 in catalyzing aliphatic dinitrile. In particular, the enzyme can regioselectivity catalyze the formation of 5-cyanopyramides from adiponitrile with high reaction rate under mild reaction conditions, which provides a new method for the industrial production of 5-cyanopyramides.
US11421208B2	Materials and methods for increasing gene editing frequency Materials and methods for gene editing using improved targeted endonucleases and endonuclease systems (e.g., Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) endonuclease systems) are provided herein.
US11421207B2	Method for producing trehalose employing a trehalose phosphorylase variant The present invention relates to a method for producing trehalose, comprising the steps of mixing and reacting, in any order, (i) at least one alpha-phosphorylase capable of catalyzing the production of alpha-D-glucose 1-phosphate intermediate from a saccharide raw material, and from at least one phosphorus source; (ii) at least one trehalose phosphorylase capable of catalyzing the production of trehalose from an alpha-D-glucose 1-phosphate intermediate and a glucose substrate, wherein the trehalose phosphorylase is a trehalose phosphorylase variant with an amino acid sequence which differs from the amino acid sequence of a wild type trehalose phosphorylase in at least one amino acid position, (iii) at least one saccharide raw material which produces an alpha-D-glucose 1-phosphate intermediate and a co-product by catalytic action of the alpha-phosphorylase; and (iv) at least one phosphorus source selected from the group consisting of a phosphoric acids and an inorganic salt thereof.
US11421204B2	Method of removing pluripotent cells from culture A stem cell removing method that certainly-removes an undifferentiated stem cell is provided. For this object, a cell group including a stem cell and a somatic cell performed differentiation induction is cultivated in culture medium composition including photosensitizer. Light of a specific wavelength is irradiated with the cell group, and the stem cell is removed, selectively. The stem cell is a pluripotent stem cell or a somatic stem cell. The pluripotent stem cell includes either an ES cell (Embryonic Stem Cell) or an iPS cell (induced Pluripotent Stem Cell). Also, somatic stem cell includes any one of a germ stem cell, a productive cell, a pluripotent stem cell and a stem cell having unipotency.
US11421203B2	Method of producing human retinal pigment epithelial cells The invention relates to a method of producing a retinal pigment epithelial cell from a human pluripotent stem cell, and a method of treating or preventing a retinal disease by using the produced cell. The retinal pigment epithelial cell is prepared by (a) inducing differentiation of a human pluripotent stem cell into a pigment cell by adhesion cultivation of a human pluripotent stem cell in a medium containing a Nodal signal inhibitor and a Wnt signal inhibitor in the absence of a feeder cell to give a culture containing the pigment cell, (b) subjecting the obtained culture to further adhesion culture to give a culture containing a pigment cell colony, and (c) isolating the pigment cell from the obtained culture and culturing the cell to give a retinal pigment epithelial cell.
US11421201B2	Biomass with bioengineered yeast, associated organic compounds, and related methods Provided are various genetically engineered strains of TEKK microorganisms, e.g., yeast in a container of industrial-scale volume containing biomass, wherein the microorganisms are capable of fermenting C5 material to produce desirable organic compounds. Also provided are methods for efficiently producing industrial-scale volumes of the desirable organic compounds, e.g., lactic acid, by TEKK strains of microorganisms such as TEKK-LAC and variants thereof.
US11421199B2	Recombinant yeast and use thereof Provided is a recombinant yeast expressing germacrene A synthetase or a fusion protein thereof, wherein the fusion protein is germacrene A synthetase and farnesyl pyrophosphate synthase. The recombinant yeast improves the yield of germacrene A, and is suitable for the industrialized production of β-elemene and/or germacrene A.
US11421197B2	Apparatus for controlling fermentation of natural material An apparatus for controlling fermentation of natural material. The apparatus includes one or more sensors configured to measure at least one property of natural material, a container configured to contain a chemical reactive agent reducing or limiting a fermentation process of the natural material; a valve coupled with the container; and a controller configured to process the measured at least one property of the natural material, and, if the processing meets a predetermined condition, control the valve to open so that the chemical reactive agent is released into the natural material in order to limit the fermentation process of the natural material.
US11421195B2	Culture device Provided is a culture device, including: a culture tank (110) configured to store an object liquid that is a culture solution having suspended therein an object; a screen (210) made of a metal, the screen including a main body (212) and a plurality of through holes (214) passing through the main body from a front surface (212a) thereof to a back surface (212b) thereof; a spray portion (220) configured to spray the object liquid stored in the culture tank onto the front surface of the body; an accommodation portion (240) surrounding the back surface of the main body and configured to accommodate the culture solution having passed through the through holes; a UV light irradiation portion (250) arranged in the accommodation portion and configured to radiate UV light; and a return portion (290) configured to return the culture solution in the accommodation portion to the culture tank.
US11421182B2	Oil extraction apparatus An oil extraction apparatus includes an ultrasonication vessel that receives raw plant material and ethanol. An ultrasonication probe ultrasonicates the raw plant material received in the ultrasonication vessel and generates a mixture including ultrasonicated raw plant material, plant oil, and ethanol. A collection vessel is in fluid communication with the ultrasonication vessel. The collection vessel receives a mixture including plant oil and ethanol from the ultrasonication vessel. A heater heats the collection vessel to separate ethanol from the mixture including plant oil and ethanol. A reclamation vessel is in fluid communication with the collection vessel. The reclamation vessel receives separated ethanol from the mixture including plant oil and ethanol. An ethanol collection tube is connected with the reclamation vessel. The ethanol collection tube is arranged to carry separated ethanol from the mixture including plant oil and ethanol to the reclamation vessel from the collection vessel.
US11421175B2	Gear oil composition for automobile, and lubrication method Disclosed are a gear oil composition for automobiles containing at least (A) a base oil, (B) a sulfur-based extreme pressure agent, and (C) a phosphorus-based extreme pressure agent and satisfying specific requirements (i) and (ii), which is excellent in seizing resistance and wear resistance and also in fuel-saving performance, and a lubrication method using the gear oil composition.
US11421172B2	Fluoropolyether compound, lubricant using same, and usage thereof Provided are a lubricant that is highly resistant to contamination and highly thermally stable, a lubricant that is highly durable and highly heat resistant, and a magnetic disk. A fluoropolyether compound contains perfluoropolyether groups, end groups each containing at least one hydroxyl group, and a linking group that is comprised of a C4-C14 hydrocarbon group and that contains at least one hydroxyl group.
US11421170B2	Mineral base oil, molded article, and method for producing mineral base oil Provided are a mineral base oil satisfying the following requirements (I) to (IV), which is excellent in safety and environmental aspects and has good compatibility with resin; a molded article formed of a resin composition containing the mineral base oil and a resin; and a method for producing the mineral base oil. Requirement (I): The flash point is 200° C. or higher. Requirement (II): The pour point is 0° C. or lower. Requirement (III); The aromatic content (% CA) is 2.6 or more. Requirement (IV): The toluene content, as measured according to JIS A1965:2015, is more than 0 μg/m3 and less than 500 μg/m3.
US11421167B2	Integrated pyrolysis and hydrocracking units for crude oil to chemicals Integrated pyrolysis and hydrocracking systems and processes for efficiently cracking of hydrocarbon mixtures, such as mixtures including compounds having a normal boiling temperature of greater than 450° C., 500° C., or even greater than 550° C., such as whole crudes for example, are disclosed.
US11421165B2	Disaggregation of biomass pyrolysis oil Described is a novel process for disaggregating biomass pyrolysis oil quantitatively into energy dense hydrophobic aromatic fraction (HAF), fermentable pyrolytic sugars and phenolics based products in a highly economical and energy efficient manner. Phase separation of the esterified pyrolysis oil after an oxidative pre-treatment and the quantitative recovery of the separate fractions is described. Phase separation uses batch as well as continuous reactor systems. The resulting HAF is an energy dense, thermally stable, water free, non-corrosive to carbon steel, and is a free flowing liquid suitable for combustion and for upgrading to transportation fuels. Pyrolytic sugars which are mainly anhydrosugars can be further converted by fermentation to ethanol or other products. Monomeric phenols are useful industrial intermediates and the organic acids in the original pyrolysis oil are mainly recovered as esters of the separation solvents.
US11421158B2	Methods for expanding and enriching hydrocarbon diluent pools The invention provides a method for enriching diluents with butane so as not to violate pre-defined limits for liquid hydrocarbon fuels with respect to density, volatility and low density hydrocarbon content.
US11421150B2	Methods for improving hydrocarbon production from an unconventional subterranean formation Disclosed are compositions and methods for the pressure protection of existing wells during infill drilling operations. The methods can include injecting an aqueous pressure protection composition into an unconventional subterranean formation via an existing wellbore in fluid communication with a rock matrix of the unconventional subterranean formation prior to and/or during injection of a fracturing fluid into the unconventional subterranean formation via a new wellbore in fluid communication with the rock matrix of the unconventional subterranean formation; and producing a hydrocarbon from the existing wellbore during and/or after the injection of the fracturing fluid into the unconventional subterranean formation via the new wellbore.
US11421149B2	Alkyl polyglycoside surfactants for use in subterranean formations Methods and compositions for treating subterranean formations with treatment fluids comprising alkyl polyglycoside surfactants are provided. In one embodiment, the methods comprise providing a treatment fluid comprising an aqueous base fluid; and a surfactant comprising an alkyl polyglycoside or derivative thereof; introducing the treatment fluid into a wellbore penetrating at least a portion of a subterranean formation; and producing fluids from the wellbore during or subsequent to introducing the treatment fluid into the wellbore.
US11421147B2	Aqueous formulations of surfactants and associative polymers for the assisted recovery of petroleum An aqueous formulation for enhanced oil recovery may include at least one surfactant and at least one associative polymer. The associative polymer may be obtained by micellar radical polymerization by bringing into contact, in an aqueous medium, hydrophilic monomer dissolved in the aqueous medium, hydrophobic monomers in the form of a micellar solution, at least one radical polymerization initiator, and preferably at least one radical polymerization control agent.
US11421145B2	Oil recovery methods using a formulation containing an unsaturated zwitterionic surfactant and a polymer A method of recovering oil from a reservoir using an aqueous composition that contains an unsaturated zwitterionic surfactant and a copolymer. The unsaturated zwitterionic surfactant is an amidoamine-based surfactant having a sulfonate head group and an alkenyl tail. The copolymer contains reacted units of acrylamide and 2-acrylamido-2-methylpropane sulfonic acid (AM-AMPS). This method is particularly effective for enhanced oil recovery in carbonate reservoirs of high temperature and/or high salinity.
US11421144B2	Delayed release of resin curing agent A variety of systems, methods and compositions are disclosed for delayed release of a resin curing agent. An example method may comprise introducing a treatment fluid comprising a resin and delayed release curing agent particulates into a subterranean formation, wherein the delayed release curing agent particulates comprises a carrier, a curing agent disposed on the carrier, and a coating; degrading the coating; and curing the resin in the subterranean formation.
US11421142B2	Composition which makes it possible to delay the formation of gas hydrates Provided is a composition comprising at least one polymer, the repeat unit of which comprises at least one amide functional group, at least one polyetheramine with a weight-average molecular weight (Mw) of greater than 100 g.mo1−1 and exhibiting at least two secondary and/or tertiary amine functional groups, and optionally, but preferably, at least one organic solvent. Also provided is method of using of the composition for delaying, indeed even preventing, the formation of gas hydrates, in particular in a process for extracting oil and/or gas and/or condensates, and also to the process for delaying, indeed even preventing, the formation and/or the agglomeration of gas hydrates, employing a composition as defined above.
US11421136B2	Working fluid for heat cycle, composition for heat cycle system, and heat cycle system A working fluid for heat cycle, a composition for a heat cycle system containing the working fluid, and a heat cycle system employing the composition are provided. The working fluid has a low global warming potential and can replace R410A. The working fluid contains trifluoroethylene, 2,3,3,3-tetrafluoropropene, and optionally a hydrofluoroolefin other than trifluoroethylene and 2,3,3,3-tetrafluoropropene. The total proportion of trifluoroethylene and 2,3,3,3-tetrafluoropropene based on the entire amount of the working fluid is from 70 to 100 mass %.
US11421134B2	Pressure-sensitive adhesive composition and use therefor An adhesive composition which contains a vinyl polymer and an acrylic adhesive polymer, and wherein: the vinyl polymer has a glass transition temperature (Tg) of from 60° C. to 200° C. (inclusive) and a number-average molecular weight of from 500 to 10,000; and the vinyl polymer is contained in an amount of from 0.5 part by mass to 60 parts by mass per 100 parts by mass of the acrylic adhesive polymer. If this adhesive composition is applied to a separator and then dried, thereby obtaining an adhesive layer, a first Tg that is the glass transition temperature of the entire adhesive layer is from −80° C. to 10° C., and a second Tg that is the glass transition temperature calculated from a surface layer portion of the adhesive layer as determined by X-ray photoelectron spectroscopy is 40° C. or higher, and is higher than the first Tg by 30° C. or more.
US11421131B2	Polishing composition and method for producing same Provided is a polishing composition which contains a water-soluble polymer and is suitable for reducing LPDs. The polishing composition provided in this application includes an abrasive, a water-soluble polymer, and a basic compound. In the polishing composition, the content of a reaction product of a polymerization initiator and a polymerization inhibitor is 0.1 ppb or less of the polishing composition on a weight basis.
US11421128B2	Composition of spin-on materials containing metal oxide nanoparticles and an organic polymer A coating composition, and uses thereof, including a solvent, metal oxide nanoparticles dispersed in this solvent, and a high carbon polymer dissolved in this solvent, where the high carbon polymer includes a repeat unit of structure (1), a hydroxybiphenyl repeat unit of structure (2) and a moiety containing a fused aromatic containing moiety of structure (3) where R1 and R2 are independently selected from the group of hydrogen, an alkyl and a substituted alkyl, Ar is an unsubstituted or substituted fused aromatic ring and X1 is an alkylene spacer, or a direct valence bound.
US11421126B2	Vinyl polymer microparticles, and masterbatch and resin film containing the same Provided are vinyl polymer microparticle which can reduce an average volume of the microparticles dropping off from a film surface while reducing the friction of the film. The vinyl polymer microparticles satisfy the following (1) to (3):(1) a coefficient of variation of particle sizes is 30% or more on a volume basis;(2) a proportion of vinyl polymer microparticles having a particle size of 1.7 times or more and 2.5 times or less a volume average particle size is 0.040% or less on a number basis; and(3) a volume average particle size is 3.7 μm or more.
US11421123B2	Dispersion and jettable composition containing cesium tungsten oxide nanoparticles and a zwitterionic stabilizer An example of a dispersion includes cesium tungsten oxide nanoparticles, a zwitterionic stabilizer, and a balance of water. An example of a jettable composition includes cesium tungsten oxide nanoparticles, a zwitterionic stabilizer, a surfactant, a co-solvent, and a balance of water. A method for improving the stabilization of a jettable composition includes incorporating a zwitterionic stabilizer in the jettable composition, which includes the cesium tungsten oxide nanoparticles, the surfactant, the co-solvent, and the balance of water.
US11421122B2	Aqueous ink, ink for inkjet recording, printed material and method for producing printed material A problem to be solved by the invention is to provide an aqueous ink capable of forming a clear print image without causing deterioration in print quality due to uneven drying (mottling) of the ink even when continuous printing is performed for a long period of time or when printing is resumed after printing is suspended for several minutes to several hours. The invention relates to an aqueous ink containing: an acetylene-based surfactant (A); a nonionic surfactant (B) other than the acetylene-based surfactant (A); and an aqueous medium (C), in which the nonionic surfactant (B) contains a nonionic surfactant that satisfies at least one of the following three requirements: (i) having an HLB of less than 13.5, (ii) having a clouding point of 75° C. or lower, and (iii) having no clouding point.
US11421120B2	Ink composition, method for producing the same, and image-forming method An ink composition contains: water; and a particle including a photopolymerizable monomer and a polymer having a blocked isocyanate group having an unblocking temperature of 150° C. or less.
US11421119B2	Resin composition, and three-dimensional moulding production method The purpose of the present invention is to provide a liquid resin composition which includes polysaccharide nanofibres, and which is used in a three-dimensional moulding production method in which a moulding obtained by curing the resin composition by irradiating the resin composition with active energy rays is three-dimensionally formed, wherein unevenness in strength in the height direction is not readily produced in the formed three-dimensional moulding. The present invention relates to a liquid resin composition which is used to produce a three-dimensional moulding, and which three-dimensionally forms a moulding as a result of being cured by being selectively irradiated with active energy rays. The resin composition includes an active energy ray-curable compound and polysaccharide nanofibres. The ratio of the number of polysaccharide nanofibres having a branched structure to the total number of polysaccharide nanofibres is less than 20%.
US11421111B2	Radar frequency transparent effect pigment mixture, formulations and coatings thereof This invention deals with effect pigment mixture comprising platelet-like aluminum effect pigments obtained by grinding of aluminum or aluminum based alloy shot and silvery pearlescent pigments, wherein the silvery pearlescent pigments are taken from the group consisting of: a) pearlescent pigments comprising a transparent substrate which is coated with a high-refractive index layer with n>1.8, which comprises or consists of an iron-oxide with Fe(II)-ions, b) pearlescent pigments comprising a transparent substrate which is coated with a high-refractive index layer with n>1.8, which comprises or consists of titanium suboxide or a pearlescent pigment comprising a substrate with a high-refractive index with n>1.8 layer, which comprises or consists of a titanium suboxide that is optionally coated with a high-refractive index layer with n>1.8, c) pearlescent pigments comprising a transparent substrate which is coated with a high-refractive index layer with n>1.8, which comprises or consists of titanium oxynitride, d) pearlescent pigments comprising a transparent substrate which is coated with a layer comprising carbon, wherein the carbon is enclosed in a particulate form in another metal oxide layer or is formed as a separate, individual layer, e) a transparent substrate coated with a first layer comprising or consisting of a mixture of the oxides of titanium, iron and at least one of cobalt and chromium and a second layer on the first layer, wherein the second layer comprises an oxide of titanium, and mixtures or combinations of the pearlescent pigments a) to e) or pearlescent pigments with mixtures or combinations of the various coating layers mentioned in the pearlescent pigments a) to e), wherein the weight ratio of the pearlescent pigment to the aluminum effect pigment is in a range of 0.4 to 5.0. The invention deals also with a coating formulation containing this effect pigment mixture.
US11421108B2	Curable organopolysiloxane compositions Addition curable composition containing specific silicone resins containing aliphatically unsaturated groups and an organic compound containing unsaturated groups such as acrylate or methacrylate groups are suitable when used with fine and coarse fillers to produce artificial stone with both high hardness and high flexural strength.
US11421105B2	Low specific gravity PET composite material A use of a low specific gravity PET composite material that is suitable for manufacturing a tableware article by injection molding is provided. The tableware article provides a balance between aesthetic appearance and food safety and can be used in place of melamine tableware. The low specific gravity PET composite material includes 66.5-96.3 wt % of PET, 0-20 wt % of PBT, 3-10 wt % of an inorganic filler, 0.1-0.5 wt % of an antioxidant, 0.1-1 wt % of a processing aid, and 0.5-2 wt % of a nucleating agent, and the total amount of all components is 100 wt %.
US11421097B2	Container sealant composition Disclosed is a container sealant composition with improved can sealing performance and reduced hot water absorption. The composition comprises a latex of a carboxylated styrene-butadiene rubber, a filler (preferably kaolin clay), an organosilane, and a tackifier. Also disclosed is a method of sealing a can with the aforedescribed container sealant composition.
US11421096B2	Compositions comprising vinylidene fluoride polymers and adsorbent carbon materials Composition comprising a) a polymer comprising recurring units derived from vinylidene fluoride monomer and at least one monomer carrying at least one functional group selected from carboxyl groups, ester groups and hydroxyl groups, and b) a microporous adsorbent carbon material having a specific surface area (BET) of at least 700 m2/g, a pore volume in the range of from 0.1 to 0.7 m3/g, at least 60% of said pore volume being formed by micropores having a pore radius of 2 nm or less.
US11421095B2	Methods of recycling and reshaping thermosetting polymers and composites thereof Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
US11421092B2	Method for preparing unidirectionally aligned discontinuous fiber reinforcement composite material, unidirectionally aligned discontinuous fiber reinforcement composite material, and sandwich structure Provided are a method for preparing a unidirectionally aligned discontinuous fiber reinforcement composite material, a unidirectionally aligned discontinuous fiber reinforcement composite material, and a sandwich structure. The method for preparing a unidirectionally aligned discontinuous fiber reinforcement composite material comprises discontinuously aligning short fibers on a polymer substrate in one direction by using an air-laid method.
US11421090B2	Systems, devices, and methods for promoting in situ polymerization within nanomaterial assemblies The present disclosure is directed to synthesizing a nanomaterial-polymer composite via in situ interfacial polymerization. A nanomaterial is exposed to a solution having a first solute dissolved in an aqueous solvent to uniformly, or substantially uniformly, distribute the solvent throughout the porosity of the network of the nanomaterial. The nanomaterial is then exposed to a second solution having a second solute dissolved in an organic solvent, which is substantially immiscible with the first solvent, with the first solute reacting with the second solute. The first and second solutions can be stirred, or otherwise moved with respect to each other, to facilitate transport of the second solution throughout the nanomaterial to promote reaction of the polymer within the nanomaterial to produce a polymer composite having uniform morphology.
US11421087B2	Carbon fiber composite, a medium incorporating the carbon fiber composite, and a related method Carbon fiber composite additives, media incorporating the carbon fiber composites, and related methods are provided herein. In some aspects, a composition includes at least one medium; and a carbon fiber composite incorporated with the at least one medium, the carbon fiber composite including one or more carbon fibers with an epoxy resin matrix applied thereto to produce a composition having improved characteristics and filtration performance.
US11421086B2	Processes for forming fluoropolymer articles The present invention relates to a process for producing a fluoropolymer article having a high surface roughness and high coarseness which comprises the following steps: a) forming a paste comprising a fluoropolymer into a paste-formed fluoropolymer product at a temperature lower than 50° C., b) densifying the paste-formed product, and c) stretching the densified paste-formed fluoropolymer product in at least one direction. The present invention further relates to a fluoropolymer article obtainable by a process according to the invention.The present invention furthermore relates to a fiber comprising, or consisting of, a fluoropolymer having a surface roughness expressed as a peak to valley distance (Rt) greater than 10 micrometer and/or an average surface roughness (Ra) greater than 1.5 micrometer.The present invention furthermore relates to a membrane comprising, or consisting of, a fluoropolymer having a coarseness index ρ/EBP of at least 0.3, an air permeability of 15 ft3/ft2/min or higher and a node aspect ratio of below 25.
US11421076B2	Highly heat-resistant polycarbonate ester and preparation method therefor A heat-resistant, bio-based polycarbonate ester prepared by melt polycondensation of 1,4:3,6-dianhydrohexitol and a carbonate, 1,4-cyclohexanedicarboxylate, or a terephthalate is disclosed. The heat-resistant, bio-based polycarbonate ester includes a repeat unit 1 of Formula 1, a repeat unit 2 of Formula 2, and a repeat unit 3 of Formula 3: The polycarbonate ester has excellent heat resistance, transparency, and processability. A method of producing the polycarbonate includes a step of melt polycondensation of 1,4:3,6-dianhydrohexitol and a carbonate, 1,4-cyclohexanedicarboxylate, or a terephthalate.
US11421075B2	Curative A curative for epoxidized plant-based oils and epoxidized natural rubber is created from the reaction between a naturally occurring polyfunctional acid and an epoxidized plant-based oil is disclosed. The curative may be used to produce porosity-free castable resins and vulcanize rubber formulations based on epoxidized natural rubber. Materials made from disclosed materials may be advantageously used as leather substitutes.
US11421068B2	Method for producing organyloxysilyl-terminated polymers Metal catalysts employed in the preparation of organyloxysilyl-functional, moisture curable polymers, are deactivated by cheating with specific chelating agents. Compositions containing the polymers exhibit improved storage stability.
US11421067B2	Acrylic polyester resin and an aqueous coating composition containing the same There is described an aqueous coating composition, the aqueous coating composition comprising an acrylic polyester resin, obtainable by grafting an acrylic polymer and a polyester material, the polyester material being obtainable by polymerizing: (i) a polyacid component, with (ii) a polyol component. At least one of the polyacid component and/or the polyol component comprises a functional monomer operable to impart functionality on to the polyester resin, such that an acrylic polymer may be grafted with the polyester material via the use of said functionality. The coating composition further containing a crosslinking material, wherein the crosslinking material comprises material according to formula (I); as shown in claim 1; wherein R1 is selected from aryl (such as C4 to C24 aryl), or aralkyl (such as C5 to C25 aralkyl); R2 to R5 are each independently hydrogen, alkyl (such as C1 to C20 alkyl), aryl (such as C4 to C24 aryl), aralkyl (such as C5 to C25 aralkyl) or —CHR8OR9; wherein R8 and R9 are each independently hydrogen, alkyl (such as C1 to C20 alkyl), aryl (such as C4 to C24 aryl), aralkyl (such as C5 to C25 aralkyl), alkoxyalkyl (such as C2 to C40 alkoxyalkyl) or an alkaryl (such as C5 to C25 alkaryl); wherein at least one of R2 to R5, is —CHR8OR9, suitably all of R2 to R5, are —CHR8OR9.
US11421065B2	Adhesive resin composition and adhesive sheet Provided are an adhesive resin composition capable of forming an adhesive layer excellent in holding force, wet heat clouding resistance, and low corrosiveness; and an adhesive sheet. The adhesive resin composition includes a (meth)acrylic copolymer (A) having a constituent unit derived from a macromonomer (a) and a constituent unit derived from a vinyl monomer (b), in which the (meth)acrylic copolymer (A) has at least one of an amide bond and a radical polymerizable group.
US11421058B2	Modified polytetrafluoroethylene and method for producing same A modified polytetrafluoroethylene which can be formed under a low extrusion pressure and with which changes of the extrusion pressure are suppressed, even in paste extrusion at a high RR ratio, and its production method. The modified polytetrafluoroethylene having units based on tetrafluoroethylene, 0.020 to 0.040 mass % of units based on a monomer represented by the following formula (1), and 0.003 to 0.080 mass % of units based on a monomer represented by the following formula (2), each based on all units of the modified polytetrafluoroethylene. The monomers of formulae (1) and (2) are represented by: CH2═CH—CnF2n+1 (1), wherein n is from 2 to 6; and CF2═CFO(LO)mRf (2), wherein L is a perfluoroalkylene group, Rf is a perfluoroalkyl group, and m is an integer of from 0 to 4.
US11421056B2	Polyolefin polymer composition The present disclosure is generally directed to polyolefin polymers, such as polypropylene homopolymers, and propylene-ethylene copolymers that have improved flow properties. In one embodiment, the polymers can be produced using a solid catalyst component that includes a) dissolving a halide-containing magnesium compound in a mixture, the mixture including an epoxy compound, an organic phosphorus compound, and a hydrocarbon solvent to form a homogenous solution; b) treating the homogenous solution with an organosilicon compound during or after the dissolving step; c) treating the homogenous solution with a first titanium compound in the presence of a first non-phthalate electron donor, and an organosilicon compound, to form a solid precipitate; and d) treating the solid precipitate with a second titanium compound in the presence of a second non-phthalate electron donor to form the solid catalyst component, where the process is free of carboxylic acids and anhydrides.
US11421052B2	Treatment of epoxidized unsaturated isoolefin copolymers A process for producing a crosslinked polymer involves contacting an epoxidized unsaturated isoolefin copolymer with a catalytic amount of an acid in an absence of a solvent. A process for producing a hydroxylated unsaturated isoolefin copolymer involves contacting an epoxidized unsaturated isoolefin copolymer with a catalytic amount of an acid in an absence of a solvent. A hydroxylated unsaturated isoolefin copolymer having hydroxyl groups in endo configurations may be produced thereby.
US11421050B2	Long chain branched polypropylene via polymerization with aluminum vinyl transfer agent The present disclosure provides the use of quinolinyldiamido transition metal complexes, an activator and a metal hydrocarbenyl chain transfer agent, such as an aluminum vinyl-transfer agent, to produce long chain branched propylene polymers.
US11421047B2	Crosslinked polymeric network and use thereof A packaging system for the storage of an ophthalmic device includes a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising one or more crosslinked polymeric networks. The one or more crosslinked polymeric network comprises a reaction product of a first glycosaminoglycan, a second glycosaminoglycan, and a first crosslinking agent, wherein the first glycosaminoglycan is different than the second glycosaminoglycan. The aqueous packaging solution has an osmolality of at least about 180 mOsm/kg, a pH of about 6 to about 9 and is heat sterilized.
US11421042B2	Use of molar mass controlled cellulose According to an example aspect of the present invention, there is provided a use of molar mass controlled cellulose in injection molding, extrusion and three dimensional printing applications.
US11421040B2	Antibodies specific for FLT3 and their uses The present invention provides antibodies that specifically bind to FLT3 (Fms-Like Tyrosine Kinase 3). The invention further provides bispecific antibodies that bind to FLT3 and another antigen (e.g., CD3). The invention further relates to antibody encoding nucleic acids, and methods of obtaining such antibodies (monospecific and bispecific). The invention further relates to therapeutic methods for use of these antibodies for the treatment of FLT3-mediated pathologies, including cancer such as Acute Myeloid Leukemia (AML).
US11421035B2	Stable antibody variable domain framework combinations and methods of use thereof The present invention relates to novel antibody variable domain combinations with advantageous properties.
US11421030B2	BTLA antibodies This invention relates generally to antibodies or antigen binding fragments that bind to human B and T lymphocyte attenuator (BTLA) and uses thereof. More specifically, the invention relates to agonistic antibodies that bind human BTLA and modulate its activity, and their use in treating inflammatory, autoimmune and proliferative diseases and disorders.
US11421027B2	CD3 binding antibodies The present invention relates to human CD3 antigen-binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also relates to bispecific antibody molecules capable of activating immune effector cells and their use in diagnosis and/or treatment of various diseases.
US11421024B2	Agents, uses and methods for the treatment of synucleinopathy The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
US11421022B2	Method for making antibody Fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof Herein is reported a method for producing an antibody Fc-region conjugate comprising as first component an antibody Fc-region and as second component at least one binding entity that specifically binds to a target using a transpeptidase for enzymatic conjugation of the antibody Fc-region to at least one binding entity.
US11421021B2	Immunogenic compositions comprising Staphylococcus aureus leukocidin LukA and LukB derived polypeptides The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides methods of inducing an immune response against a LukAB-expressing S. aureus, methods of preventing or treating S. aureus infections, and composition for preventing or treating S. aureus infections.
US11421020B2	Antibodies that neutralize RSV, MPV and PVM and uses thereof The invention relates to antibodies, and antigen binding fragments thereof, that neutralize infection of both RSV, MPV and PVM. The invention also relates to nucleic acids that encode, immortalized B cells and cultured plasma cells that produce, and to polypeptides that bind to such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and polypeptides recognized by the antibodies of the invention in screening methods as well as in the diagnosis, treatment and prevention of RSV or MPV infection and RSV and MPV co-infection.
US11421011B2	Polynucleotides encoding tethered interleukin-12 (IL12) polypeptides and uses thereof The present disclosure relates to polynucleotides encoding tethered interleukin-12 (IL-12) polypeptides comprising an IL-12 polypeptide and a membrane domain. The present disclosure also relates to vectors comprising the polynucleotides; host cells comprising the polynucleotides or vectors, polypeptides encoded by the polynucleotides; compositions comprising the polynucleotides, vectors, host cells, or polypeptides and a delivery agent; and uses thereof, including treatment of cancer.
US11421009B2	Pharmaceutical composition containing, as active ingredient, granulocyte-colony stimulating factor mutant protein or transferrin fusion protein thereof The present invention relates to a fusion protein in which transferrin is peptide-bonded to a terminal of a granulocyte-colony stimulating factor (G-CSF) protein or a G-CSF mutant protein in which the 116th threonine is substituted with cysteine in the amino acid sequence of the G-CSF. Specifically, the granulocyte-colony stimulating factor (G-CSF) mutant protein of the present invention or the transferrin fusion protein thereof displays a significantly increased specific activity and blood stability, compared with the conventional human G-CSF, and has a higher purification efficiency than the conventional PEGylated G-CSF characterized by the extended half-life, so that it can be advantageously used for preventing or treating ischemic diseases or neutropenia.
US11421008B2	Anti-tumor properties of Dickkopf 3b The invention relates to novel therapeutic approaches to cancer treatment that exploits tumor suppressor functions of DKK3b by site-specific delivery of DKK3b. Novel therapeutics and methods for treating tumors and cancers utilizing DKK3b tumor suppressor functions are disclosed.
US11421000B2	Pharmaceutical composition and the use thereof in the treatment of autoimmune diseases The present invention relates to compounds comprising formula I: Amino Acid Sequence-(L)n-DMARD wherein the amino acid sequence comprises QKRAAYDQYGHAAFE-NH2 (SEQ ID NO: 1), DMARD is a disease modifying antirheumatic agent, L is a linker unit; —is a covalent bond and n is 0 or 1 and methods of using the compound for treatment of autoimmune diseases. In a preferred embodiment the DMARD is selected from Chloroquine and Hydroxychloroquine.
US11420999B2	Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives Disclosed herein are non-natural amino acids and dolastatin analogs that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The dolastatin analogs can include a wide range of possible functionalities, but typically have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid dolastatin analogs that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such dolastatin analogs. Typically, the modified dolastatin analogs include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid dolastatin analogs and modified non-natural amino acid dolastatin analogs, including therapeutic, diagnostic, and other biotechnology use.
US11420997B2	Peptide synthesis method The present invention has an object of shortening the process time and reducing use of a poor solvent for solidifying a carrier (Tag)-peptide component, by removing impurities without conducting solid-liquid separation (condensation, solid-liquid separation and drying operation) of a Tag-peptide component, in an Fmoc method using a Tag for liquid phase peptide synthesis. Provided is the peptide synthesis method that includes the following steps a-d: step a: a carrier-protected amino acid, carrier-protected peptide, or a carrier-protected amino acid amide, and an N-Fmoc-protected amino acid or an N-Fmoc-protected peptide are condensed in an organic solvent or a mixed solution of organic solvents, to obtain an N-Fmoc-carrier-protected peptide, step b: a water-soluble amine is added to the reaction solution after the condensation reaction, step c: the Fmoc group is deprotected from the protected amino group in the presence of a water-soluble amine, and step d: the reaction solution is neutralized by adding an acid, and further, by adding and washing with an acidic aqueous solution, then, by liquid-liquid separation an aqueous layer is removed to obtain an organic layer.
US11420991B2	Confined porphyrin Co(II) and preparation method and application thereof A confined porphyrin Co(II), which is prepared by the following method: Equimolar amounts of aromatic aldehyde and pyrrole are condensed under acidic conditions to synthesize phenyl porphyrin compounds; the phenyl porphyrin compounds are metallized in a chloroform-methanol solution to obtain porphyrin Cu(II), which is brominated and demetallized to obtain confined porphyrin; the confined porphyrin is stirred and refluxed in a methanol solution for 12.0-24.0 h to obtain confined porphyrin Co(II). Its application is as follows: The confined porphyrin Co(II) is dissolved in cycloalkanes; the reaction system is sealed, and heated to 100 to 130° C. with stirring, to which oxygen is introduced to 0.2 to 3.0 MPa; the reaction is carried out for 3.0 to 24.0 h with stirring with the set temperature and oxygen pressure being maintained; and then the reaction solution is subjected to post-treatment to obtain the products.
US11420990B2	Ruthenium complex containing alkynyl group, method of synthesizing the same and use thereof A Ruthenium complex containing alkynyl group, a method of synthesizing the Ruthenium complex containing alkynyl group and a use thereof are provided. The Ruthenium complex has a chemical formula of Ru(L)2(DPPZ′). DPPZ′ is a main ligand having structural formula of R is any one selected from the group consisting of H, substituted or unsubstituted phenyl, R1NH2, R1OH, and SiMe3; R1 is C1-C5 chain alkyl group; L is an auxiliary ligand with N as coordinating atom. Sonogashira coupling reaction is utilized to introduce alkynyl group into a DPPZ-type Ruthenium complex; the introduced alkynyl group is beneficial to promote the transmembrane absorption of drug molecules, increase the probability of drug entry into cells, and can also increase efficacy and reduce toxic and side effects of drugs. The Ruthenium complex provided has significant anti-tumor activity, especially anti-breast cancer activity, and can provide new ideas for designing anti-tumor drug molecules in the future.
US11420987B2	Triaryl phosphine ligands, preparation method therefor, and use in catalysing coupling reactions Provided are triaryl phosphine ligands, as shown in general formulae Ia and Ib, or a mixture thereof, and a preparation method therefor. The invention addresses the deficiencies of biaryl phosphine ligands invented by Buchwald et al. Also provided are a triaryl phosphine coordinated palladium complex, a system composed of triaryl phosphine ligand and a palladium salt or complex, and a use of the triaryl phosphine coordinated palladium complex in catalysing organic reactions, in particular a use in catalysis of coupling reactions involving (pseudo)halogenated aromatic hydrocarbon as substrate.
US11420985B2	Acetoxy systems Reaction system for preparing acetoxy function-bearing siloxanes having chain lengths of more than 3 silicon atoms, comprising silanes and/or siloxanes bearing alkoxy groups, silanes and/or siloxanes bearing acetoxy groups, silanes and/or siloxanes bearing hydroxy groups and/or simple siloxane cycles and/or DT cycles, and also a reaction medium comprising acetic anhydride, Brønsted acid and acetic acid, wherein Brønsted acids having a pKa ≤−1.30 are used, and wherein the acetic acid is present in the reaction system in amounts of 0.4 to 15.0 percent by weight, based on the reaction system, wherein the molar ratio of Brønsted acid used to acetic acid is in a defined range, with the proviso that either the sole use of trifluoromethanesulfonic acid and also of trifluoromethanesulfonic acid and acetic acid is excluded, and/or that the Brønsted acid used at least in part has a pKa between −1.3 and >−13.5.
US11420984B2	Arginase inhibitors and methods of use thereof Disclosed are compounds of formula (Ia) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of formula (Ia) and methods of using the same for treating cancer or a respiratory inflammatory disease and inhibiting arginase: wherein R1 is —NHR1a; R1a is —H or —C(O)CH(R1b)NHR1c; R1b is selected from —H, —(C1-C4) alkyl and CH2OR1d; R1c is —H; or R1b and R1c, together with the atom to which they are attached, form a 5-membered heterocyclic ring; and R1d is H or —CH3.
US11420983B2	Molecular hydrogen adsorbent comprising copper-BTC MOF Mixed metal metal-organic frameworks (MM-MOFs) of copper-1,3,5-benzenetricarboxylate (BTC), M—Cu-BTC, wherein M is Zn(II), Ni(II), Co(II), and/or Fe(II) may be made using post-synthetic exchange (PSE) with metal ions. Such MM-MOFs may be used in H2 storage, especially Ni(II) and Co(II) MM-MOFs. Selected metal exchanged materials can provide gravimetric H2 uptake around 1.63 wt. % for Zn—Cu-BTC, around 1.61 wt. % for Ni—Cu-BTC, around 1.63 wt. % for Fe—Cu-BTC, and around 1.12 wt. % for Co—Cu-BTC.
US11420978B2	Method for synthesizing 3-phenyl-2,8-dihydropyrano [2,3-f] chromene derivative The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.
US11420977B2	Late SV40 (LSF) inhibitors The present invention is directed to compositions, methods and kits for treatment of cancer, e.g. heptacellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I)-(V) to inhibit tubulin methylation or to modulate chromatin or cytoskeleton modification in a cell.
US11420976B2	Heterocyclic compounds as anti-viral agents The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV) or HMPV. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV or HMPV infection. The invention also relates to methods of treating an RSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US11420968B2	Bcl-2 inhibitors Disclosed herein is a compound of Formula (I) for inhibiting Bcl-2 and treating disease associated with undesirable bcl-2 activity (Bcl-2 related diseases), a method of using the compounds disclosed herein for treating dysregulated apoptotic diseases including cancers and treating autoimmune disease, and a pharmaceutical composition comprising the same.
US11420962B2	Indene derivatives useful in treating pain and inflammation Compounds of formula (I) wherein, R1, R2, R3, R4a, R4b and R5 are described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable salt or solvate thereof, are described herein, as well as other compounds. These compounds are useful in treating inflammation and/or pain. Compositions comprising a compound of the invention are also disclosed, as are methods of using the compounds to treat inflammation and/or pain.
US11420952B2	Organotin catalysts in esterification processes of furan-2,5-dicarboxylic acid (FDCA) Sugar-based mono and diesters are prepared by esterification of 2,5-furan-dicarboxylic acid (FDCA) with an alcohol in the presence of low loadings of a homogeneous organotin (IV) catalyst.
US11420950B2	Heterocyclicalkyl derivative compounds as selective histone deacetylase inhibitors and pharmaceutical compositions comprising the same The present invention relates to novel heterocyclicalkyl derivatives having histone deacetylase (HDAC) inhibitory activity, optical isomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel heterocyclicalkyl derivatives. The novel heterocyclicalkyl derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be effectively used for the treatment of histone deacetylase-mediated diseases, such as cell proliferative diseases, inflammatory diseases, autosomal dominant diseases, genetic metabolic diseases, autoimmune diseases, acute/chronic neurological disease, hypertrophy, heart failure, ocular diseases, or neurodegenerative diseases.
US11420944B2	Voltage-dependent t-type calcium channel blocker A compound represented by the following General Formula (I), a tautomer or a stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, is used as a voltage-dependent T-type calcium channel blocker: wherein A represents a 5-membered heteroaryl group or a fused ring of a 5-membered or 6-membered heterocyclic ring with a benzene ring or a pyridine ring, each of which may have a substituent; R represents a hydrogen atom or the like; B represents CR5(Q1) or NQ2, herein Q1 represents a benzimidazole group which may have a substituent, or the like; Q2 represents an alkyl group having 1 to 8 carbon atoms which may have a substituent, a heteroaryl group which may have a substituent, or the like; R0, R1, R2, R3, R4, and R5 each represent a hydrogen atom or the like; and n and m each represent 0, 1, or 2.
US11420942B2	Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine The present invention relates to crystalline forms of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethylamine (“COMPOUND I”) useful in the treatment of RAGE mediated diseases.
US11420936B2	Hypoxia inducible factor-2(alpha) inhibitors and their use in the treatment of diseases The present disclosure is directed certain Hypoxia Inducible Factor 2α (HIF-2α) inhibitors and their use in the treatment of diseases mediated by HIF-2α such as cancer. Also provided is the use of HIF-2α inhibitors in combination with a poly (ADP-ribose) polymerase (PARP) inhibitor. In particular, the present disclosure is directed to methods for the treatment of cancers using a HIF-2α inhibitor in combination with a PARP inhibitor and pharmaceutical compositions comprising the same.
US11420934B2	PPAR agonists Provided herein are compounds and compositions useful in increasing PPARδ activity. The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
US11420933B2	Lipids and lipid compositions for the delivery of active agents This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R4, L1, n and p are defined herein. The compounds of formula (X) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
US11420931B2	Lipid containing formulations Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described.
US11420929B2	Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPARδ and may be useful for treating conditions mediated by the same.
US11420925B2	Reduction method and reduction product of alkenyl active methylene compound Disclosed are a reduction method and reduction product of an alkenyl active methylene compound. The reduction reaction comprises the following steps: taking an alkenyl active methylene compound as a substrate, a metal hydride as a reducing agent, and a palladium compound as a catalyst, performing a reduction reaction to obtain a reduction product, and then reducing the alkenyl active methylene compound. The reduction system is a simple method for reducing the alkenyl active methylene compound, and the used hydride and palladium compound catalyst are both reagents that could easily be obtained in a laboratory. Compared with conventional hydrogen hydrogenation methods and reduction methods of reducing agents, the method is easier to operate, higher in safety, mild in conditions, and high in reaction yield, a reaction in a one-pot two-step manner can be achieved, and high atom economy and step economy can be obtained.
US11420918B2	Method for producing a hydroxy compound by decarboxylation in the absence of a catalyst The invention relates to a method for producing a specific hydroxyl compound by decarboxylating a specific carboxylic acid compound or a salt of said carboxylic acid compound in the absence of a catalyst and to a method for producing a bisphenol.
US11420911B2	Catalyst containing LF-type B acid and method for preparing ethylene using direct conversion of syngas A catalyst containing LF-type B acid preparing ethylene using direct conversion of syngas is a composite catalyst and formed by compounding component A and component B in a mechanical mixing mode. The active ingredient of the component A is a metal oxide; the component B is a zeolite of MOR topology; and a weight ratio of the active ingredients in the component A to the component B is 0.1-20. The reaction process has an extremely high product yield and selectivity, with the selectivity for light olefin reaching 80-90%, wherein ethylene has high space time yield and can reach selectivity of 75-80%. Meanwhile, the selectivity for a methane side product is extremely low (<15%).
US11420909B2	Method for enantiomeric enrichment According to the present invention there is provided a method for enantiomeric enrichment of a mixture of two enantiomers of a chiral compound, the method comprises the application of the mixture of two enantiomers of a chiral compound onto a surface of a support material for producing a coated support, the determination a first value of an optical activity (OA0) of the coated support, the irradiation of the coated support with a light beam having an intensity at least higher than a desorption threshold of one of the enantiomers from the coated support, wherein, if the support material is achiral, the light beam is circularly polarized and, if the support material is chiral, the light beam is unpolarized, linearly polarized or circularly polarized, and the determination of a second value of the optical activity (OAe) of the coated support after said irradiation, wherein the second value of the optical activity (OAe) differs from the first value of the optical activity (OA0).
US11420906B2	Synergistic disposal method of hazardous waste incineration residues and solid wastes, ceramsite and application thereof A synergistic disposal method of hazardous waste incineration residues and solid wastes, ceramsite and an application thereof, all belonging to the field of resources and environment. The disposal method includes the following steps: mixing of the hazardous waste incineration residues and solid wastes, granulation and dehydration of the resulting mixture and calcination to obtain ceramsite. In the preparation of ceramsite by the synergistic disposal of hazardous waste incineration residues and solid wastes as the raw materials, dioxin and organic matters in the hazardous waste incineration residues and solid wastes are decomposed, meanwhile the contained heavy metals are reduced and solidified, solving the disposal problem of hazardous waste incineration residues and solid wastes, saving a lot of land for landfills, decreasing the cost for comprehensive disposal, not producing new hazardous wastes, and reducing the burden of ecological environment.
US11420905B2	Ceramic substrate and production method for same The present invention focuses on a silicon nitride substrate having high mechanical strength, high thermal conductivity and the like, and takes advantage of such properties to provide: a ceramic substrate capable of providing improvement in a bonding property between a silicon nitride substrate and a ceramic layer which uses a dielectric ceramic material capable of being simultaneously sintered with a low-resistance conductive material such as a low-melting metal (Ag or Cu); and a method for producing the ceramic substrate. The ceramic substrate of the present invention is obtained by stacking and bonding a silicon nitride substrate and a ceramic layer composed of a dielectric ceramic material, wherein: the dielectric ceramic material contains Mg, Al, and Si as main ingredients, and Bi or B as an accessory ingredient; and the ceramic layer includes a region with a high Si element concentration at a bonding interface with the silicon nitride substrate.
US11420902B2	Material comprising a stack with thermal properties A material includes a transparent substrate on which is deposited a stack of layers including n silver-based metal functional layers and n+1 dielectric sets of layers, with n≥3 and each silver-based metal functional layer being placed between two dielectric sets of layers. The dielectric set of layers located below the first silver-based metal functional layer starting from the substrate and the dielectric set of layers located above the last silver-based metal functional layer starting from the substrate each include a high-refractive-index layer, the value of the index≥2.15 at the wavelength of 550 nm; the value of the refractive index of at least one of the high-index layers≥2.40 at the wavelength 550 nm; and the value of the ratio of the optical thickness of each of the high-refractive-index layers to the optical thickness of the dielectric set of layers in which it is included is included between 0.25 and 0.55.
US11420901B2	Coated glass or glass ceramic substrate, coating comprising closed pores, and method for coating a substrate Coated glass or glass ceramic substrates having high temperature resistance, high strength, and a low coefficient of thermal expansion. The coating includes pores, is fluid-tight and suitable for coating a temperature-resistant, high-strength glass or glass ceramic substrate with a low coefficient of thermal expansion, and to a method for producing such a coated substrate.
US11420896B2	Cobalt-based alloy with a high resistance at high temperatures, spinner for the production of mineral fibers comprising said alloy and process for the production of mineral fibers which uses such a spinner The present invention relates to a metal alloy, characterized in that it comprises, in percent by weight on the total weight of the alloy, 1-4% of niobium (Nb), 0-0.5% of hafnium (Hf), 27-29% of chromium, 1-5% of nickel (Ni), 0.3-0.45% of carbon (C), 0-2% of tantalum (Ta), 0-2% of titanium, 1-3% of iron, less than 0.5% of manganese (Mn), less than 0.3% of silicon (Si), less than 0.2% of zirconium (Zr), the remainder being cobalt (Co) and unavoidable impurities. This metal alloy has superior mechanical strength characteristics at high temperature which make it suitable for the manufacture of a manufactured article, in particular a spinner, for the production of mineral fibers, such as glass fiber, rock fiber and the like.
US11420888B2	Treatment process and device for submerged lifting circulation type bio-membrane filter The present invention discloses a treatment process for a submerged lifting circulation type bio-membrane filter, wherein the treatment process comprises the following steps: two groups of symmetrically staggered filter curtains (2A and 2B) are adopted; the two groups of filter curtains (2A and 2B) are periodically lifted up and down in a reciprocating manner in a biofilter (1) under the action of a lifting mechanism (4), so that bio-membranes on the two groups of filter curtains (2A and 2B) are in contact with the atmosphere and sewage in turns, absorb organic matters in the sewage when lifting down for submerging, absorb oxygen when lifting up and exposing into to the atmosphere, and bring oxygen into the sewage and cause sewage turbulence in a water tank when lifting down for submerging again, so that the dissolved oxygen is uniformly distributed, thereby purifying the sewage.
US11420887B2	Real-time dewatering optimization Provided for example is a system and method for real-time monitoring or controlling wastewater or sludge dewatering or thickening processes. The system and method can also enable operators to remotely monitor their own system off-site.
US11420886B2	Method for purifying water A method for purification of water with a water purifier. The water purifier includes an anode and a cathode as electrodes in such a way that a gap remains between the anode and the cathode. In the method, an electric field is generated between the anode and the cathode, water for purification is conveyed to the gap and an additive enhancing floc formation is introduced to water for purification or to purified water in an amount of less than 50 g and at least 1 g, measured as dry matter, per each cubic metre of water for purification. Floc material manufactured with the method, when water for purification is municipal wastewater. The use of the floc material produced in this way as a soil conditioner or for manufacturing a soil conditioner.
US11420878B2	Methods for removal of lead and/or other contaminants from limestone and resultant calcium oxide Systems and methods for impurity removal to limestone using modifications to the typical calcination process of turning calcium carbonate into calcium oxide. Specifically, substantially increasing the temperature to 1100° C. or higher and increasing soak time can result in reductions in certain undesirable impurities, particularly with regards to lead and lead compounds.
US11420873B2	Graphenic carbon nanoparticles having a low polyaromatic hydrocarbon concentration and processes of making same Provided are graphene nanosheets having a polyaromatic hydrocarbon concentration of less than about 0.7% by weight and a tap density of less than about 0.08 g/cm3, as measured by ASTM B527-15 standard. The graphene nanosheets also have a specific surface area (B.E.T.) greater than about 250 m2/g. Also provided are processes for producing graphene nanosheets as well as for removing polyaromatic hydrocarbons from graphene nanosheets, comprising heating said graphene nanosheets under oxidative atmosphere, at a temperature of at least about 200° C.
US11420871B2	Polyoxometalate compound and method for producing same, sintered body of polyoxometalate compound, and reaction catalyst Disclosed is a polyoxometalate compound including a metal-substituted polyoxometalate. The metal-substituted polyoxometalate includes a polyoxometalate having defect sites, a substituting metal atom introduced into the defect sites, and an organic ligand. The substituting metal atom is divalent platinum or palladium. The organic ligand may be a bidentate ligand having an aliphatic heterocycle containing two nitrogen atoms coordinately bonded to the substituting metal atom. One substituting metal atom is introduced into one defect site.
US11420870B2	Method for directly synthesizing sodium borohydride by solid-state ball milling at room temperature The present invention discloses a method for directly synthesizing sodium borohydride by solid-state ball milling at room temperature, which comprises: performing solid-state ball milling on a mixture of a reducing agent and a reduced material by using a ball mill under room temperature, and performing purification to obtain sodium borohydride. The reducing agent comprises one or more of magnesium, magnesium hydride, aluminum, calcium, and magnesium silicide. The reduced material is sodium metaborate containing crystallization water or sodium metaborate, or is a mixture of sodium metaborate containing crystallization water and sodium metaborate. The solid-state milling is performed in a mixed atmosphere of argon and hydrogen, or an argon atmosphere, or a hydrogen atmosphere. The present invention has a simple process, a controllable and adjustable reaction procedure, mild reaction conditions, low energy consumption, low costs, high yield, no pollution, good safety, and easy industrial production.
US11420868B2	Method for the preparation of synthesis gas Method for the preparation of synthesis gas combining electrolysis of carbon dioxide, autothermal reforming and 5 optionally tubular steam reforming of a hydrocarbon feed stock.
US11420862B2	Fuel management system for a fuel dispensing facility including a fuel deliver system Fuel management systems for a fuel dispensing facility including a fuel delivery system are disclosed. The fuel delivery system includes at least one storage tank configured to contain a fuel, at least one dispenser configured to receive the fuel from the at least one storage tank, and a fuel handling system which is configured to one of (1) deliver the fuel to the at least one storage tank, (2) receive the fuel from the at least one storage tank, (3) monitor for a leak within the fuel delivery system, and (4) monitor for a fuel inventory within the fuel delivery system. The fuel management system may include installation records of the fuel handling components. The fuel management system may monitor cameras positioned in sumps of the fuel delivery system. The fuel delivery system may include a camera positioned to monitor an interior of a sump, the interior of the sump being provided by a sump basin and a sump cover. The sump cover may be a sump lid. The sump cover may be a dispenser. The sump cover may be another portion of the fuel delivery system.
US11420861B2	Dispenser with haptic feedback touch-to-pour user interface Described herein are example systems and methods of user interfaces on a product dispenser. The product dispenser includes a touch-to-pour user interface configured to provide a pattern of haptic feedback to a user while a touch is sensed on the touch-to-pour user interface. At the same time, the product dispenser is configured to dispense a product while the touch is sensed on the touch-to-pour user interface. The pattern of haptic feedback is dependent upon the product being dispensed from the product dispenser.
US11420857B2	Fork adjuster for a forklift truck, forklift truck provided therewith and method for adjusting forks The invention relates to a fork adjuster, forklift truck provided therewith and method for adjusting forks. The fork adjuster according to the invention comprises: a frame provided with coupling means configured to operatively couple the fork adjuster to the forklift truck; an adjusting mechanism arranged in or on the frame and configured to adjust the forks; a drive mechanism which can be connected operatively to the adjusting mechanism for driving the adjusting mechanism, wherein the drive mechanism is provided with contact means such that the adjusting mechanism is driveable by contact of the contact means with a ground surface.
US11420850B2	Retracting rail clamp A retracting rail clamp for braking or anchoring a rail-mounted machine such as a crane by clamping opposite sides of a longitudinal rail member, the retracting rail clamp comprising: a load transfer frame rigidly secured to the crane, such as by bolting; and a clamp mechanism suspended within the load transfer frame by at least one lateral pair of pivotally mounted lift levers, and operable through a first and second stage of motion between a raised, brake release position, in which the entirety of the rail clamp is disposed substantially vertically clear of the rail, and a lowered, brake set position wherein at least one opposed facing pair of main levers of the clamp mechanism engage the side surfaces of the rail.
US11420849B2	Traction machine and lifting equipment The present application relates to the technical field of lifting equipment, and provides a traction machine and a lifting equipment. The traction machine includes traction pulleys, traction ropes driven by the traction pulleys and fixed pulleys for changing directions of the traction ropes. The fixed pulley is provided with a sensor sensing member rotating with the fixed pulley, a traction machine sensor is arranged beside the fixed pulley; the traction machine sensor is configured to detect a rotation speed of the sensor sensing member, and send the rotation speed to a controller of the traction machine; the controller controls a rotation of the traction pulley according to detected data of the traction machine sensor. Since this kind of traction machine is provided with the sensor sensing member and the traction machine sensor, it is capable of detecting whether the traction machine has an abnormal operation, and stopping the traction machine immediately in an abnormal state.
US11420844B2	Elevator system Provided is an elevator system capable of improving the operation efficiency of an elevator. An elevator system according to the present invention includes: first processing circuitry to receive destination floor information transmitted from a movable body having a movement mechanism and second processing circuitry and being capable of boarding and alighting from a car of an elevator, to assign the car, in which a plurality of onboard positions are set, to a call based on the destination floor information received, and to assign one of the plurality of onboard positions to one movable body based on a destination floor of the movable body. The first processing circuitry transmits to the movable body information indicative of the onboard position assigned to the movable body.
US11420842B2	System and method for heat assisted saddle finisher folding A system and method for assembling booklets in document finishers such as saddle staplers includes first and second opposed rollers configured to receive an edge of a stapled crease of a stack of printed documents. The rollers apply both heat and pressure to the crease to form a tight fold. A second set of rollers provides further heat and pressure to the fold to increase tightness even further. Pressure and temperature of one or both roller sets is controllable to accommodate paper stacks having different numbers of pages or different paper characteristics.
US11420840B2	Method for franking packages individually supplied from a stack by a franking machine A method for franking packages individually supplied from a stack on a conveyor line to a franking machine, such as envelopes, mailing bags, sleeves, cards, labels, printed products, or the like, which are removed at the lower side of the stack for separation and which are supplied on the upstream conveyor line to a printing mechanism of the franking machine and which, after printing of the packages, are discharged from the franking machine. The packages are supplied on the conveyor portion via a switch to the franking machine and after printing are supplied counter to the supply direction from the printing mechanism of the franking machine via the transposed switch of a depositing device which is provided therebelow for printed packages.
US11420833B2	Linear sorter having variably running cross-belt supports A linear sorter sorts piece goods. The linear sorter contains a closed circulation of tracks having a plurality of cross-belt elements, in which the piece goods are transported on an upper run on the cross-belt elements and are sorted by unloading to corresponding destination points, and the cross-belt elements return on a lower run. The cross-belt elements are driven by linear motors. In order to simplify the maintenance and to have to keep fewer cross-belt elements available as replacement components, the linear motors for the cross-belt elements are controlled such that, as the cross-belt elements return on the lower run, the speed of the cross-belt elements is higher than the speed of the cross-belt elements while travelling on the upper run.
US11420832B2	Transport fixing jig Provided is a transport fixing jig that has a high gripping force, hardly contaminates an object to be processed (object to be transported), and is excellent in heat resistance. The transport fixing jig of the present invention includes: a first base material; a carbon nanotube aggregate; and an adhesive layer arranged between the first base material and the carbon nanotube aggregate, wherein the first base material and the carbon nanotube aggregate are bonded to each other via the adhesive layer, and wherein a ratio (adhesive layer/base material) between a linear expansion coefficient of the first base material and a linear expansion coefficient of the adhesive layer is from 0.7 to 1.8.
US11420827B2	Belt scraper and method for operating a belt scraper A belt scraper having a scraper element to be brought into abutment with a belt. The scraper element is pivotably arranged with reference to a pivoting axis. A spring element generates a torque acting on the scraper element. A sensor for determining a pivoting angle of the scraper element is a contactless sensor with an index part and a detecting part for detecting the position of the index part. The index part is arranged, at a distance from the pivoting axis, on a movable element that is coupled to the scraper element.
US11420823B1	Consolidation and transportation of items An inventory management system can include a mobile sorting assembly for sorting and transporting items to storage locations. The mobile sort assembly can receive and sort an item, move the item to storage location, and transfer the item to the storage location. The mobile sorting system can include a platform for receiving and positioning the items and one or more sorting shelves for receiving the items.
US11420821B2	Garbage can retention clip The invention includes two interconnecting side release buckles configured to releasable connect to each other. A pair of webbing separately secured to one of the opposing ends of one of the side release buckles. Each of the webbing has a distal end with a stitched loop. A pair of D-rings secured within the stitched loops and secured to either the garbage can or lid by an attachment. Fasteners are secured through attachments and secured to the garbage can or lid, such that when the two interconnecting side release buckles are connected the hinged lid is prevented from opening away from the trash can.
US11420818B2	Movable cover for fluid containment tanks A system for covering fluid containment tanks to contain vapors and minimize evaporation of the vapors into the surrounding atmosphere. The system includes a flexible cover and restraint elements, guiding rails which support the cover over a tank and provide guidance for extending and retracting the flexible cover, a belt drive extends the leading end of the flexible cover and a drivable drum provides a way to retract the flexible cover and upon which the flexible cover will be rolled and stored, and a method to locate tank elements beneath the flexible cover system to prevent operating interferences.
US11420816B2	Air reservoir assembly for a submergible enclosure The present technology relates to an air reservoir for an enclosure where, upon submersion in water, the pressure differential between the water and the enclosure displaces air from the air reservoir into the enclosure to reduce the pressure differential.
US11420815B2	Low profile transportable holding tank A holding tank system for holding a waste, the holding tank system including: a holding tank including a floor disposed in a first plane, the holding tank configured to be supported on at least one joist disposed in a second plane, wherein the second plane is disposed at an incline with respect to the first plane.
US11420814B2	Rapidly cooling food and drinks Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
US11420812B2	Storage container, microneedle unit, storage container group, and method of producing microneedle unit Provided are a storage container, a microneedle unit, a storage container group, and a method of producing a microneedle unit that enable protection of a microneedle array before puncture and realization of a puncturing property of the microneedle array using a simple member.The storage container, which stores a microneedle array including a sheet having a first surface and a second surface that oppose each other and a plurality of needles arranged on the first surface of the sheet, includes a first member having an edge portion that defines a second opening and a second member having a depression, in which the microneedle array is stored by superimposing the second member on the first member, and the second member and the first member are deformed by applying a force to the second member in a state in which the second member is superimposed on the first member, and the needles of the microneedle array are allowed to protrude from the first member to puncture a skin.
US11420811B2	Collar support strap for shirt packaging A single piece of collar support strap to package collar portion of a shirt is described. Shirt collars are traditionally packaged in a way to reflect the collar's positioning and shape in actual use. Conventional methods employ multiple pieces of support items placed in different locations. A collar support strap provides the positioning of the collar in a packaged shirt not only through a single piece item, but also provides ease of packaging by avoiding multiple steps of operations to package the shirt. The collar support strap enables adjustment to varying collar sizes, anchoring to the collar button, and accommodation of the different collar types.
US11420810B1	Refillable solution dispensing device A refillable solution dispensing device includes a housing having an upper section and a lower section. An actuator exposed through the exterior of the upper section. The actuator is movably connected to an air chamber and a solution chamber. The solution chamber is in fluid communication with the solution reservoir and a discharge nozzle. The air chamber is fluidly connected to the discharge nozzle. The actuator is coupled to a mixing shaft that protrudes into the lower section. The lower section comprises an interior volume that functions as a solution reservoir. A solution cartridge and water are inserted into the solution reservoir. A solution mixer is rotatably coupled to the mixing shaft combining the solution within the solution cartridge, the solution cartridge, and the water into one solution. Upon an activation of the actuator, the solution and the air will mix and exit the discharge nozzle.
US11420809B1	Tissue container A tissue container including a housing, a top opening, a bottom opening, and a membrane disposed inside the housing. The housing has a top wall, a bottom wall, and four side walls between the top and bottom walls. The top opening is in the top wall and tissue can be dispensed therethrough. The bottom opening is in the bottom wall and tissue can be inserted therethrough. The membrane is disposed inside the housing between the top wall and the bottom wall to divide the housing into an upper compartment and a lower compartment. The upper compartment is above the membrane and the lower compartment is below the membrane. The membrane has a center portion and a perimeter portion surrounding the center portion. The perimeter portion may be connected the top wall, the bottom wall, or the four side walls. The center portion is flexibly movable between a first position at which the center portion is closer to the bottom wall than to the top wall and a second position at which the center portion is closer to the top wall than to the bottom wall.
US11420805B2	Fragile object holding device provided with protecting mechanism A device for stably maintaining the shape of a fragile object in a liquid includes a container for accommodating the fragile object, a lid member for sealing the container, and a protecting member. The device is configured to form a liquid-tight space by covering a liquid surface in the container which accommodates the fragile object and the liquid with the protecting member and further covering the protecting member and an open portion of the container with the lid member.
US11420804B2	Detachably securable container assembly for a unit load device A container assembly configured for loading into/onto a Unit Load Device (ULD) generally includes first and second containers. Rearward sides of the first and second containers include a securing catchment assembly for mating and securing the first and second containers. Frontward sides of the first and second containers each include a plurality of female/male door securing assemblies that complementarily mate with male/female door securing assemblies of a door assembly. When the first and second containers are mated, the container assembly defines an outer perimeter that is smaller than an inner perimeter of the ULD. The outer perimeter of the container assembly has a shape generally conforming with the shape of the inner perimeter of the ULD. One or more shock absorption assemblies/airbag assemblies configured to reduce vibration and movement of the container assembly are disposable between one or more walls of the ULD and the first and second containers/container assembly.
US11420801B2	Metal sheet for containers and method for manufacturing same A metal sheet for containers includes a metal sheet and a polyester film which is laminated on a surface of the metal sheet to be an inner surface side of containers. The polyester film contains a wax in an amount of 0.010 to 2.000 mass %, and has a dipole-dipole force of 40 mN/m or less.
US11420800B2	Packaging system and method of using same A reusable packaging system for a gift, comprising: a decorative wrapping for wrapping around the gift so that the gift is concealed thereby, the decorative wrapping defining a plurality of mounting apertures; and a mount securable to the gift independently from the decorative wrapping, the mount being provided with a wrapping attachment insertable in each of the mounting apertures. The decorative wrapping is movable between attached and detached configurations. In the detached configuration, the decorative wrapping is detached from the mount. In the attached configuration, with the mount secured to the gift, the decorative wrapping is attached to the mount and encloses the gift, the decorative wrapping being secured to the wrapping attachment with the wrapping attachment inserted through at least some of the mounting apertures.
US11420796B2	Recyclable bag Front and back panels have side seams that fix the panel side edges of the front panel to the panel side edges of the back panel and each extend a full vertical length of the respective panel side edges. A label formed from a separate piece of film covers one of the face panels between the side edges thereof, is disconnected from the one face panel between the panel side seams, has label side edges generally at the respective side panel edges, and secures the label to the one face panel. Respective secondary side seams are provided between the side edges of the label and the side edges of the one panel, and respective tear lines are formed in the label closely adjacent and generally parallel to each of the label side edges. There is printing on the label only between the tear lines.
US11420794B2	Transparent container with fitted insert Embodiments of the subject invention are directed to a transparent container with an insert that maintains its form and position when fit snugly inside of the container. The container and insert material are chosen to take advantage of inherent properties including stiffness, static friction and static cling such that no further fastening material, such as glue, is needed to secure the insert inside the container.
US11420793B2	Paint bucket insert A paint bucket insert. The paint bucket insert includes a base dimensioned to removably secure within a bucket, wherein an annular sidewall extends orthogonally away from the base along a perimeter thereof. The base is further concave defining an apex. A well is disposed within the base at the apex, wherein the well extends from a lower side of the base. The well can receive a paint sprayer hose or alternatively a paint roller therein.
US11420791B2	Plastic pallet with handle The invention relates to a plastic pallet having an underside provided with skids and an upper side, wherein one skid runs along the centre of the plastic pallet and the skid along the centre has a handle which may be gripped from the underside of the pallet. The handle is preferably arranged on the underside of the central skid preferably parallel to the surface of the upper side and preferably along the central longitudinal axis of the central skid.
US11420789B2	Pallet made of plastic having reinforcing elements A pallet includes a cover plate configured to accommodate articles, and at least two runners arranged underneath the cover plate, each runner including a runner standing surface, wherein each runner standing surface is subdivided centrally of each runner transversely thereto at a dividing plane and into at least two separate runner elements including a first runner element and a second runner element which, in the mounted position, combine to form the runner standing surface, and wherein each runner element includes an elongated reinforcing element which is held at a first end remote from the dividing plane by a stop in the first runner element and is held at a second end by the second runner element.
US11420788B2	Collapsible wall scooping storage system A storage system includes a floor; a pair of end walls hingedly and detachably affixable to the floor; a pair of side walls hingedly and detachably affixable to the floor; and a cover hingedly and detachably affixable to one of the end walls.
US11420787B2	Bottom chime and beverage keg The present invention relates to a bottom chime for a beverage keg. The bottom chime is configured to be push fitted onto the keg, and to subsequently be removable from the keg, for example to enable recycling of the bottom chime separately to the keg. The bottom chime comprises a plurality of inwardly extending engagement elements that are configured to form a snap fit engagement with a corresponding plurality of recesses provided in the body of the keg.
US11420783B1	Bottles for packaging liquids for retail A bottle for packaging a beverage for retail includes a floor and at least one wall extending upwardly from the floor. The floor and the at least one wall collectively define part of a watertight cavity. A primary spout extends from the at least one wall and has a distal opening spaced apart from the at least one wall. Secondary and tertiary openings are located along the at least one wall or the primary spout and are in communication with the watertight cavity. The secondary opening has an internal perimeter smaller than an internal perimeter of the primary spout distal opening. Primary, secondary, and tertiary closures are configured to removably seal the primary spout distal opening, the secondary opening, and the tertiary opening. A tube has a flared receptacle end and a submersible end configured to pass through the secondary opening for adding content to the watertight cavity.
US11420782B2	Automatic ground-coffee capsule manufacturing machine This invention involves with a kind of coffee machine, especially involves with a kind of automatic coffee grinding capsule making machine. The machine consists of the base, automatic rotating operation platform, coffee cup unloading device, coffee bean grinding device, coffee powder temporary storage device, powder tamping and removal device, coffee cap unloading device and capping device; the said automatic rotating operation platform is provided at the said base; the said automatic rotating operation platform can rotate based on the coffee capsule making status. This invention discloses the non-industrial and automatic coffee capsule maker that integrates coffee bean grinding, powder tamping and injection for capsule and capsule capping and improves the licensed process of such maker. This invention has more compact structure, smaller volume and lower cost, and can be operated simply and conveniently.
US11420781B2	Packaging device and packaging process A method and a baling system includes at least one baler (14) for producing highly compressed bales (2) made of artificial fibers. The baler (14) includes a securing device for applying a securing device (3), in particular strapping, to the compressed bales (2). A packaging device (1) applies a bale casing (4) that is closed on all sides to the secured compressed bales (2). The packaging device (1) includes a production and application device (21) for producing a sleeve-type casing (5) and for the application thereof to the compressed bales (2), as well as a sealing device (22) for closing and sealing axial ends (6, 7) of the sleeve-type casing (5) on the uncovered sides of the bales.
US11420780B2	Binding machine A binding machine includes a wire feeding unit configured to feed a wire to be wound on an object to be bound, a binding unit configured to twist the wire wound on the object to be bound, a curl guide configured to curl the wire being fed by the wire feeding unit, an inductive guide configured to guide the wire curled by the curl guide toward the binding unit, and a retraction guide part configured to retract the wire to a downstream side of the binding unit with respect to a feeding direction of the wire that is fed by the wire feeding unit in a direction of curling the wire by the curl guide.
US11420771B2	System and method for providing electrical power to a tethered aerial vehicle An aerial vehicle electrical power system for use with a tethered aerial vehicle, and related methods are provided. The aerial vehicle electric power system includes a plurality of light-emitting diodes (LEDs) carried by an aerial vehicle. At least one electrical circuit is carried by the aerial vehicle. The at least one electrical circuit has a DC buck converter electrically in series with at least a portion of the plurality of LEDs. A tether is connected between the aerial vehicle and a power source positioned remote from the aerial vehicle. Electrical power is transmitted to the aerial vehicle and at least a portion of the plurality of LEDs through the tether. The electrical circuit minimizes variances in power supplied to the aerial vehicle and the plurality of LEDs.
US11420765B2	Aircraft fuselage with internal current return network A lightning strike protection (LSP) system minimizes or eliminates both the direct and indirect effects of lightning strikes on aircraft with composite fuselages without adding excessive weight to the aircraft. The LSP system comprises an external current return network and an internal current return network. The internal current return network comprises a wide plane of conductive foil material adhered to, or embedded within, an innermost surface of the fuselage and other portions of the aircraft formed primarily of composite materials. The conductive foil material is provided in wide planar sheets, and in one embodiment, is formed of expanded copper foil mesh. The internal current return network is installed in all areas or zones of the aircraft where cables and wires are routed.
US11420763B2	Fuel delivery system having a fuel oxygen reduction unit A fuel system is provided for an aircraft having a fuel source. The fuel system includes a fuel oxygen reduction unit defining a liquid fuel supply path, a stripping gas supply path, a liquid fuel outlet path, and a stripping gas return path, wherein the stripping gas return path is in airflow communication with the fuel source.
US11420762B2	Rotor assembly A rotor assembly including a rotor mast, a rotor hub coupled to the rotor mast, a plurality of rotor blades coupled to the rotor hub, a control tube extending through the rotor mast, a crosshead coupled to the control tube, and a mechanism configured to drive the rotor mast in rotation. Wherein the mechanism is longitudinally positioned between a top portion and a bottom portion of the control tube and translation of the control tube relative to the rotor mast causes rotation of the rotor blades about their pitch-change axes. While the crosshead is installed, the crosshead is prevented from angular rotation about the mast axis. A pin of a rotor blade assembly is captured between opposing tabs of the crosshead and movable relative to the opposing tabs in response to translation of the crosshead along the mast axis.
US11420761B2	Autonomous propeller propulsion system for an aircraft, said autonomous propeller propulsion system comprising a fuel cell An autonomous propeller propulsion system for an aircraft. The autonomous system comprises a chassis with first attachment systems which engage with second attachment systems of the wing to ensure detachable attachment of the autonomous system, a fuel cell attached to the chassis, an electric motor attached to the chassis and having an output shaft, a propshaft rotated by the output shaft, a propeller attached to the propshaft, a controller converting an electric current delivered by the fuel cells into an electric current delivered to the electric motor, a hydrogen feed duct and an air feed duct, a set of auxiliary equipment, and a first connection arrangement, which connects with a second connection arrangement of the aircraft.
US11420756B1	Systems and methods for fault detection and control in an electric aircraft A system for fault detection and control in an electric aircraft including an inertial measurement unit, the inertial measurement unit including at least a sensor configured to detect a torque datum associated with at least a propulsor. The system includes an observer, the observer configured to generate a torque prediction datum associated with the at least a propulsor, compare the torque prediction datum with the torque datum, and generate a residual datum as a function of the comparison. The system includes a mixer, the mixer comprising circuitry configured to generate, as a function of the residual datum, a torque priority command datum and transmit, to the at least a propulsor, the torque priority command datum.
US11420754B2	Unmanned flight equipment, alarm device, aerial vehicle, and alarm device release apparatus An unmanned flight equipment according to an embodiment of the present invention includes: an aerial vehicle capable of flying in an unmanned manner; an abnormality recognition part-configured to recognize an abnormal situation in which a determination is made that it is difficult for the aerial vehicle to continue flight; and an alarm device held on the aerial vehicle and configured to be detached from the aerial vehicle and to warn neighborhood of abnormality when the abnormality recognition part recognizes the abnormal situation.
US11420753B2	Apparatus and method for operating a gliding parachute/kite Disclosed is an apparatus and method for operating a gliding parachute/kite. The gliding parachute/kite has a wing with a flexible material, and a set of suspension lines adapted for coupling a load to the wing, such that the coupling is configurable in any one of a plurality of possible states based on relative lengths of the suspension lines. In some implementations, the possible states include a first state enabling gliding in a first direction, and a second state enabling gliding in a second direction that is opposite to the first direction. Reversing direction is possible with the first and second states. Additionally, or alternatively, the possible states include a spinning state enabling spinning of the gliding parachute/kite. Adjusting a rate of decent is possible with the spinning. Reversing direction and/or spinning operations can be used to improve control of trajectory.
US11420751B2	Multi-latch assembly for selective retention of aircraft passenger tray table and/or other deployable components A multi-latch assembly may be utilized, for example, in an aircraft passenger seat to hold separately deployable components such as a tray table and secondary member for separately supporting a personal entertainment device. The multi-latch assembly can include a first latch member and a second latch member. The first latch member can include a first arm. The first latch member can further include a first shaft that extends from the first arm and that is at least partially hollow. The second latch member can include a second arm. The second latch member can further include a second shaft that extends from the second arm and that is received within the first shaft of the first latch member so that the first arm and the second arm are rotatable independently of one another.
US11420750B2	Consolidated electronics packages for staggered aircraft seats A set of consolidated electronics packages for staggered aircraft seats may include a first consolidated electronics package and a second consolidated electronics package. The first consolidated electronics package and a second consolidated electronics package may be installed within a primary passenger compartment. The first consolidated electronics package and the second consolidated electronics package may be configured to provide electrical connectivity to the primary passenger compartment and an auxiliary passenger compartment including an auxiliary aircraft seat. A primary aircraft seat and the auxiliary aircraft seat may be installed in a staggered configuration within an aircraft cabin including the primary passenger compartment and the auxiliary passenger compartment.
US11420749B2	Electrical connection system for a seat An electrical connecting system for a seat, in particular a passenger seat in a means of transportation, including an elongated carrier foil that is provided at least in regions with conductor tracks, the carrier foil having a first section so as to be arranged on a seat frame, a second section so as to be arranged on a backrest that may pivot and a transition section that lies between said first section and second section, wherein the transition section is embodied as V-shaped. As a consequence, an electrical connection may be achieved between an electronic unit that is arranged on a passenger seat and components that are arranged on the passenger seat.
US11420748B2	Galley cart extraction and retention system for multiple-cart bays A galley structure for an aircraft cabin includes double-depth cart bays capable of stowing an outer full-size cart in front of an inner fell-size cart. An extraction and retention (E&R) system is mounted to a sidewall of the double-depth cart bay and includes a stowable retainer arm and fixed extractor arm coupled to and articulable via an extraction handle that may be pulled or pushed out of or toward the cart bay. When the outer cart is removed, the inner cart can be brought forward for extraction via the extractor arm (the inner cart extractable once the retainer arm is stowed) and returned to its inner stowed position via the retainer arm (in both cases, by pulling or pushing the extraction handle). The extraction handle includes a retainer actuator for stowing or deploying the retainer arm as needed.
US11420746B2	Interior panel for an interior of an aircraft and a method for making the same Interior panels for interiors of aircraft, aircraft, and methods from making interior panels for interiors of aircraft are provided. In one example, the interior panel includes an outer covering that has a first surface. The first surface is configured to be exposed to the interior of the aircraft. A second surface is disposed opposite the first surface. The second surface has a first pattern formed therein that is hidden from the first surface. A first light source is operative to generate a first light and is disposed adjacent to the second surface generally aligned with the first pattern. When the first light source generates the first light, a first illuminated pattern corresponding to the first pattern formed in the second surface is visible on the first surface.
US11420743B2	Windproof aerial dispensing method and system An aerial dispensing method includes obtaining a wind velocity of a wind that causes a drift to a substance dispensed from an unmanned aerial vehicle (UAV), and controlling one or more components of the UAV based on the obtained wind velocity to cause at least mitigation to the drift.
US11420739B2	Aeronautical car and associated features An aeronautical car includes a ground-travel system including a drivetrain; an air-travel system including a detachable portion configured to house a propulsion device configured to provide thrust and to be driven by the drivetrain when the detachable portion is connected to the aeronautical car, and at least one flight mechanism configured to provide lift once the aeronautical car is in motion; and a weather manipulation device. The weather manipulation device may be configured to manipulate at least one aspect of a weather condition while the aeronautical car is in the air.
US11420736B1	System and method for vibration monitoring of an electric aircraft In an aspect, a system for vibration monitoring of an electric aircraft. A system include a propulsor. A system includes a sensor coupled to a propulsor. A sensor is configured to measure a vibration datum of a propulsor and transmit the vibration datum to a flight controller. A flight controller is configured to receive a vibration datum from a sensor. A flight controller is configured to generate a throttle datum as a function of a vibration datum. A flight controller is configured to transmit a throttle datum to a propulsor.
US11420734B2	Propeller, propeller kit, power assembly, power kit and unmanned aerial vehicle A propeller, a propeller kit, a power assembly, a power kit and an unmanned aerial vehicle (UAV). The propeller includes a hub and at least two blades connected to the hub. The hub is detachably mounted on a corresponding drive apparatus by a mounting member corresponding to the hub, so that the propeller is mounted on the corresponding drive apparatus. A surface, facing the mounting member, of the hub is provided with a first fitting portion. A surface, facing the hub, of the mounting member is provided with a second fitting portion corresponding to the first fitting portion. The first fitting portion matches the second fitting portion. In the foregoing manner, a user can be prevented from incorrectly mounting a forward propeller and a counter-rotating propeller during the use of a quick-detachable propeller in the embodiments of the present application.
US11420733B2	Additively manufactured flyaway tools for aircraft An airfoil component assembly for an aircraft includes an additively manufactured flyaway tool including an infill support core and an interface sheet surrounding the infill support core, a spar formed from one or more layers of composite material disposed on the interface sheet of the flyaway tool and a skin formed from one or more layers of composite material disposed on the spar and the interface sheet of the flyaway tool. The flyaway tool, the spar and the skin form the airfoil component assembly for use by the aircraft in flight.
US11420732B2	Aircraft and aircraft control system An aircraft includes a frame body that includes an attaching unit on an upper portion thereof, that is formed into a frame-shape structure, and that couples an object to a lower portion thereof, the attaching unit being configured to be capable of adjusting a position in an up-down direction of the attaching unit. A main body including a flying mechanism is positioned on an upper portion of the frame body. A control unit controls a position in the up-down direction of the attaching unit such that a flying posture of the object is controlled in accordance with a posture of the flying mechanism.
US11420731B2	Nose structure for an aircraft A nose structure of an aircraft includes an airframe. A wheel well assembly is coupled to the airframe and forms a portion of a nose landing gear bay. The wheel well assembly includes a pressure deck that extends from a right side of the airframe to a left side of the airframe and that forms a portion of a pressure boundary delimiting a pressurized space and a non-pressurized space. A floor-panel support is supported by the pressure deck in the pressurized space. The pressure deck and the floor-panel support form a portion of a flight deck floor of a flight deck of the aircraft. A plurality of transport elements is located between the floor-panel support and the pressure deck. The plurality of transport elements is associated with at least one high-level system of the aircraft.
US11420730B2	Management of an aircraft Methods and systems for assisting the piloting of an aircraft are provided. The system includes at least one avionics type system and at least one non-avionics type system. The method includes steps involving receiving avionics type data associated with a flying context of the aircraft; forwarding the avionics type data to a non-avionics type system or computer; determining, in the non-avionics computer, one or more adjustment recommendations for equipment based on the received flying context and/or on predetermined data; displaying one or more recommendations. Various developments are described, in particular the conditions for requesting and/or computing recommendations (e.g. ongoing adjustment of the avionics, similar previous configuration, etc.), the selection and the categorization of recommendations, the handling of adjustment data for the avionics, etc. Software aspects are described.
US11420729B2	Systems, methods and devices for determining lift heights for launching unmanned aerial vehicles Systems and methods for determining a vehicle elevation height for launching an unmanned aerial vehicle may include performing a quantitative balancing analysis using baseline factors, establishing optimal values for operational goals of a vehicle based on the quantitative balancing analysis, determining a vehicle elevation height that achieves the established optimal values for the operational goals of the vehicle by evaluating vehicle delivery parameters using normalized values, and initiating on a winch system elevation of the unmanned aerial vehicle to the determined vehicle elevation height for launching.
US11420724B2	Wheel well fairing for an aircraft A wheel well fairing for reducing drag on an aircraft fuselage configured with an open wheel well for stowing landing gear of the aircraft. The wheel well fairing includes a Coanda fairing having a convex-shaped lower portion and an upper portion. The upper portion is configured for positioning adjacent an interior vertically-orientated sidewall of the wheel well, and the convex-shaped lower portion has a bottom surface configured to extend substantially parallel to and positioned adjacent with an outer hull surface of the fuselage. The convex-shaped lower portion is curved inwardly within the wheel well between the upper portion and bottom surface. The Coanda fairing is positioned at an aft portion of the wheel well to redirect airflow out of the wheel well in a rearward direction along the bottom hull surface of the fuselage.
US11420723B2	Aircraft wing and wing tip device An aircraft wing (1) including a fixed wing (3) and a wing tip device (4) at the tip of the fixed wing (3), the wing tip device (4) being rotatable relative to the fixed wing (3) between a flight configuration (4a) for use during flight, and a ground configuration (4b) for use during ground-based operations, in which ground configuration the wing tip device (4) is rotated relative to the fixed wing (3) such that the span of the wing (1) is reduced. The aircraft wing (1) has a gear assembly (31) that couples the wing tip device (4) to an actuator (30) such that the actuator (30) drives the rotation of the wing tip device (4) between the flight and ground configurations, the gear assembly (31) comprising a worm drive (32).
US11420721B2	Internal cladding part for cladding a fuselage structure of an aircraft An internal cladding part for cladding a fuselage structure of an aircraft is disclosed having a first cover layer that extends in a planar manner, a second cover layer that extends in a planar manner, a core layer which is disposed between the first and the second cover layer and is connected to the first and the second cover layer and defines a receptacle cavity, and an insulation structure having a porous insulation core and an evacuated film sheath that encases the insulation core in a gas-tight manner. The insulation structure is disposed in the receptacle cavity between the first and the second cover layer.
US11420719B2	Shear connection for connecting airframe parts in an aircraft A shear connection for interchangeably connecting two airframe parts of an aircraft. The shear connection may include first and second interface parts. The second interface part may overlap in the longitudinal direction at an overlap section with at least one of the first interface part and the first airframe part. The shear connection may further comprise means that rigidly and non-interchangeably attach the first interface part to the first airframe part and the second interface part to the second airframe part and a shear bolt that rigidly and interchangeably connects the second interface part with the at least one of the first interface part and the first airframe part at the overlap section, thereby interchangeably connecting the first and second airframe parts.
US11420717B2	Watercraft propulsion and transportation mechanism An oar for use in propelling a watercraft through water includes a first circular paddle portion. An edge hole extends into an edge of the first paddle portion. The oar also includes a second circular paddle portion, with an edge hole extending into an edge of the second paddle portion. The oar also includes a handle portion having a first end and a second end opposite the first end. The first paddle portion edge hole and the handle portion first end are structured so that the handle portion first end is detachably securable in the first paddle portion edge hole. The second paddle portion edge hole and the handle portion second end are structured so that the handle portion second end is detachably securable in the second paddle portion edge hole.
US11420715B1	Multihull watercraft A watercraft includes: a central frame; a deck supported by the central frame; and first and second lateral hulls laterally spaced apart from one another, the central frame being disposed at least in part laterally between the first and second lateral hulls. Each of the lateral hulls includes: a plurality of lower hull panels mounted to the central frame, at least part of an outer surface of each lower hull panel forming a running surface of the watercraft; a plurality of braces connected between the central frame, the plurality of lower hull panels and the deck; and at least one buoyant element received in and substantially filling a space defined between the lower hull panels and the deck. Each brace includes: an inner mount connected to the central frame, a lower mount connected to at least one lower hull panel, and an upper mount connected to the deck.
US11420712B2	System and method for the deployment, towing and recovery of marine equipment from a waterborne carrier This document describes a system for the deployment, towing and recovery of marine equipment from a waterborne carrier, which carrier comprises a hoisting arrangement for lifting the marine equipment into the water. The system cooperates with the hoisting arrangement, and comprises a lateral deployment-recovery assembly for deployment and recovery on a lateral side of the carrier, and includes: a tow winch and an aft lateral outrigger connected to the carrier. The assembly also comprises a tow line guide and a guider winch including a guide line attachable to the tow line guide. The aft outrigger comprises a seat for the tow line guide and a sheave for the guide line to enable guiding of the tow line guide to the seat. The document also describes a method.
US11420711B2	Structure and assembly for recessed deck portion in pontoon boat A pontoon boat is provided that includes at least two pontoons running longitudinally beneath the boat and providing buoyancy thereto; a deck framework mounted above and connected to the pontoons; a deck mounted on the deck framework; a recessed deck portion extending downwardly through the deck and the deck framework, the recessed deck portion forming a cavity into the deck including a bottom and side walls forming a basin extending into and beneath the deck; and at least one seat adjacent the recessed deck portion and mounted to the deck.
US11420703B2	Scooter and method for operating a scooter A scooter with a footboard providing a contact surface for a user of the scooter, with a front axle including a first front wheel and a second front wheel and a rear axle comprising a first rear wheel and a second rear wheel, and with a steering column for steering at least the front wheels. Inclination of the footboard about a roll axis of the footboard effects a steering angle of the two front wheels in a first direction and, at the same time, a steering angle of the two rear wheels in a second direction opposite the first direction. The disclosure further relates to a method for operating such a scooter.
US11420701B2	Mirror assembly for a handlebar of a vehicle A mirror assembly for a handlebar of a vehicle has a stem assembly and a mirror connect to the stem assembly. The stem assembly includes a base, a stem connected to the base, and a clamp connected to and extending from the base. The clamp is adapted for being disposed inside a handle of the handlebar. The base, the stem and the clamp are integral. The clamp defines a ramp. A threaded fastener inserted through the base and extends in part in the clamp. A nut engages the threaded fastener, and at least a portion of the nut abuts the clamp. Translating the nut toward the base by rotating the fastener causes the nut to move over the ramp thereby deflecting the ramp.
US11420698B2	Saddle type electric vehicle A saddle type electric vehicle (1) includes a charging cord (245) that is connectable to an external power supply, a cord accommodating section (230) configured to accommodate a charging cord (245), and a step floor (9) on which an occupant places his/her legs, a center tunnel (CT) bulging above the step floor (9) is provided in front of a front end of a seat (8) and below a handle (2), and the cord accommodating section (230) is disposed in the center tunnel (CT).
US11420695B2	Semi-autonomous trailer hauler An unmanned and self-powered vehicle or Towable Autonomous Dray (TOAD) may follow a vehicle and tow a trailer, haul a load, and/or recharge a pilot vehicle. The TOAD may be semi-autonomous and may attach to a pilot vehicle by an electronic identification. Further, wireless charging of the pilot vehicle may be provided by the TOAD. Smart trailer brakes, electric trailer axles, and a mechanically coupled tow vehicle may be provided by the TOAD in combination with additional units. A smart trailer controller may include a smart head unit and a smart tail unit in a trailer that may offer trailer security and increased safety. A smart trailer brake controller on the pilot vehicle and a smart module on the trailer may be applied where no unmanned vehicle is employed, such as, in a classic pick-up/trailer combination.
US11420694B2	Robot gait planning method and robot with the same The present disclosure provides a robot gait planning method and a robot with the same. The method includes: obtaining, through the sensor set, force information of feet of the robot under a force applied by a target object; calculating coordinates of zero moment points of the feet of the robot with respect to a centroid of a body of the robot based on the force information; and determining a gait planning result for the robot based on the coordinates of the zero moment points with respect to the centroid of the body. The present disclosure is capable of converting the force of the target object to the zero moment points, and using the zero moment points to perform the gait planning, so that the robot follows the target object in the case that the robot is subjected to a force of the target object.
US11420691B2	Coupling system A coupling system includes a coupling plug and a coupling receptacle, wherein the coupling plug and the coupling receptacle engage with one another in such a way that the first coupling part makes fluid-tight contact with the first receiving part, the second coupling part makes fluid-tight contact with the second receiving part and the third coupling part makes fluid-tight contact with the third receiving part, and wherein the contact surfaces of the coupling parts and the receiving parts are substantially rotationally symmetrical about the first axis.
US11420679B2	Steering assist apparatus A steering assist apparatus is configured to, when performing a steering assist control for parking, perform one or both of the following processes (a) and (b): (a) a first setting process for setting a movement path when an oncoming lane is present, the first setting process being a process for setting the movement path in such a manner that a vehicle body does not enter the oncoming lane side from an own lane across a center line or a predetermined line obtained by translating the center line; and (b) a second setting process for setting the movement path when a following vehicle is present, the second setting process being a process for setting the movement path in such a manner that a distance between the vehicle body and a parking-possible region is less than a predetermined threshold.
US11420676B2	Sliding kingpin assembly for use in vehicles Disclosed is a truck comprising a hanger having a first pivot support and a second pivot support and an axis of rotation passing through the first pivot support and the second pivot support, a base having a structure providing the first pivot support, a pivot arm attached to the base providing the second pivot support, a pivot bushing passing through an aperture of the base, a kingpin passing through the pivot bushing, the base, and the hanger, and a locknut arranged at an end of the kingpin. In at least one example embodiment the first and second pivot support structures prevent an axis of rotation of the hanger from moving as the locknut is moved along the kingpin.
US11420674B2	Rotation detection device and electric power steering apparatus using the same An ECU includes plural sensor units and plural control units. The sensor units include magnetic field detection elements for detecting a rotation of a motor, and output mechanical angles related to the rotation angle in one rotation and count values related to the number of rotations of the motor, respectively. One rotation of the motor is divided into indefinite regions, in which detection deviation of the count values may occur, and definite regions, in which no detection deviation occurs. The definite region of the count value is set to deviate from the definite region of the other count value. Absolute angle calculation units calculate the absolute angles using the count values of the definite regions.
US11420673B2	Method for operating a steering system, and steering system In a method for operating a steering system, in particular an electrically supported steering system that includes at least one first fluid sensor unit for sensing at least one ingressing first fluid and at least one second fluid sensor unit, spatially separated from the first fluid sensor unit, for sensing at least one ingressing second fluid, at least one first response behaviour is triggered in response to the sensing of the first fluid and at least one second response behaviour, which differs from the first response behaviour at least in part, is triggered in response to the sensing of the second fluid.
US11420670B2	Steer-by-wire system and control method thereof A steer-by-wire system and a control method thereof. A reaction motor generates a reaction in a direction opposite to a direction in which a steering wheel is manipulated by a driver. A current sensor senses a phase current output by the reaction motor. A motor position sensor senses an angle of rotation of the reaction motor. A state and disturbance observer estimates a plurality of state variables and a driver torque by receiving information regarding the phase current and information regarding the angle of rotation of the reaction motor. A reaction controller determines a reaction torque output by the reaction motor, in accordance with the plurality of state variables and the driver torque estimated by the state and disturbance observer. A steering intention of a driver is accurately determined when the torque sensor or the steering angle sensor is not provided or malfunctions.
US11420666B2	Support roller, vehicle with a support roller and method for stabilizing a vehicle A support roller (30, 30′) for supporting a vehicle on an underlying surface, comprising at least one bearing element which is at least indirectly connectable to at least one supporting structure of the vehicle, at least one fork connected to the bearing element, and at least one wheel (90, 90′) which is mounted in the fork so as to be rotatable about a first rolling axis (R) and can be brought into contact with the underlying surface, at least one sensing device (190) for sensing at least one supporting force with which the wheel (90, 90′) is supported on the underlying surface. A vehicle, in particular an industrial truck, comprising at least one support roller and a method for stabilizing a vehicle.
US11420657B2	Levelling system for a vehicle, in particular a rail vehicle A levelling system for a vehicle, in particular a rail vehicle, includes at least one levelling cylinder and a levelling piston. The levelling piston is at least partially provided in the levelling cylinder in a movable manner for setting the level of the rail vehicle. Further, the levelling system includes at least one guiding element, which is arranged within the levelling piston and partially protrudes from the levelling piston into at least one recess of the levelling cylinder such that an end stop in a longitudinal direction is provided for the relative movement between the levelling piston and the levelling cylinder.
US11420655B2	System and method for safety and efficacy override of an autonomous system Described is a system for competency assessment of an autonomous system. The system extracts semantic concepts representing a situation. Actions taken by the autonomous system are associated with semantic concepts that are activated when the actions are taken in the situation. The system measures an outcome of the actions taken in the situation and generates a reward metric. The semantic concepts representing the situation are stored as a memory with the actions taken in the situation and the reward metric as a memory. A prospective simulation is generated based on recall of the memory. A competency metric and an experience metric are determined. Competent operational control of the autonomous system is maintained when at least one of the competency metric and the experience metric is above a minimum value. An alert is generated when at least one of the competency metric and the experience metric falls below the minimum value.
US11420653B2	Autonomous driving apparatus and method An autonomous driving apparatus and method, in which the apparatus includes a sensor unit detecting a surrounding vehicle around an ego vehicle that autonomously travels, an output unit, a memory storing map information, and a processor controlling the autonomous driving of the ego vehicle based on the map information. The processor is configured to generate an actual driving trajectory and expected driving trajectory of the surrounding vehicle based on driving information of the surrounding vehicle detected by the sensor unit and the map information, determine whether a driving mode of the surrounding vehicle is an autonomous driving mode and an autonomous driving risk of the ego vehicle based on a trajectory error between the actual driving trajectory and expected driving trajectory of the surrounding vehicle, and output a warning to a passenger through the output unit at a level corresponding to the determined autonomous driving risk.
US11420645B2	Method and apparatus for personalizing autonomous transportation Aspects of the subject disclosure may include, for example, a method including receiving, by a processing system at an autonomous vehicle including a processor, a personalized driving style profile associated with a first driver according to first driving information, wherein the personalized driving style profile includes key driving style parameter values associated with the first driver, wherein the first driving information comprises monitoring vehicle context and control information captured during a vehicle driving session, and modifying, by the processing system at the autonomous vehicle, a default driving style algorithm according to the personalized driving style profile to mimic at an autonomous vehicle a driving style of the first driver during operation of the autonomous vehicle. Other embodiments are disclosed.
US11420640B2	Method for autonomously operating a vehicle, controller device for a vehicle, and vehicle A method for operating an autonomously driving vehicle includes operating the vehicle in a first autonomous driving mode by means of a controller device based on sensor data captured by a sensor system of the vehicle, determining, from environmental data which includes at least the sensor data, presence of a handover condition at a handover location within a planned trajectory of the vehicle, establishing a data communication to a leading vehicle being operated in an autonomous driving mode to travel along a leading trajectory including the handover location, and operating the vehicle in a second autonomous driving mode based at least partially on first auxiliary data provided by the leading vehicle.
US11420634B2	Kalman filter based road grade estimation method using accelerometer, gyroscope, and vehicle velocity Kalman filter based road grade estimation techniques use models of a longitudinal accelerometer, an angular pitch rate gyroscope, and a velocity sensor and their outputs, and fuses the sensor measurements to optimally estimate the road grade. The proposed Kalman filter formulation is unique in that it uses a mathematical model of the sensors where the gyroscope output is considered as the input and the combined accelerometer and velocity sensor output is considered as the output of the model whose states are to be estimated. By using this unique second-order state space model, a Kalman filter based estimation algorithm is developed to estimate road grade accurately in real-time. This estimated road grade is then being utilized by various vehicle efficiency and/or safety systems to improve vehicle efficiency and/or vehicle safety.
US11420628B2	Vehicle control method and vehicle control device A vehicle control device controls a vehicle including a drive motor connected to a rotation shaft of wheels, a battery that supplies electricity to the drive motor, and an internal combustion engine connected to the drive motor. The vehicle is equipped with, as traveling modes, a normal mode, and an eco-mode having a larger regenerative braking force than the normal mode obtained such that rotational energy of the wheels is converted into electrical energy. A controller stops the internal combustion engine and switches from the normal mode to the eco-mode when detecting at least an abnormality in the internal combustion engine during traveling of the vehicle.
US11420622B2	Driving assistance apparatus A driving assistance apparatus can provide deceleration assistance of decelerating a host vehicle independently of an operation by a driver. The driving assistance apparatus is provided with: a specifier configured to specify a type of a target associated with the deceleration assistance, wherein the target is ahead of the host vehicle on a course thereof and requires the host vehicle to decelerate or stop; and a controller programmed to change an end condition associated with deceleration assistance, in accordance with the specified type.
US11420620B1	Vehicle parking assistance systems and methods Systems and methods for driver presence and position detection are disclosed herein. A method can include determining whether a vehicle is in an open area or an enclosed area, determining that a key of the vehicle is no longer present inside the vehicle and an ignition of the vehicle is on, suppressing or delaying a warning message that indicates that the key of the vehicle is no longer present inside the vehicle and the vehicle is in the open area, and providing the warning message when the vehicle is in the enclosed area.
US11420616B2	Onboard engine control for vehicles Onboard engine control for vehicles is disclosed herein. An example method includes determining a moving average of duty cycle periods for a power component of a vehicle for recent power load events, each of the duty cycle periods having both on-time portions and off-time portions; and when the on-time portions of the moving average are above a predetermined percentage, an engine of the vehicle remains in an on-state condition, further wherein when a current off-time period of the power component exceeds a value equal to a predetermined multiplier applied to the off-time portions, the engine is placed in an off-state condition.
US11420615B2	Powertrain system A powertrain system includes a control device configured, where an engine speed at the time of detection of an acceleration request with a high acceleration request index value is lower than a specific engine speed, to: set the specific engine speed as an initial target engine speed for an acceleration associated with the acceleration request; and in a first acceleration time period before reaching the initial target engine speed, control an internal combustion engine in accordance with a first target engine power based on the initial target engine speed and supply, to an electric motor, a battery power corresponding to a difference obtained by subtracting the first target engine power from a required vehicle power. The specific engine speed is a value predetermined as a lower limit value of an engine speed range in which engine sound of the internal combustion engine is heard inside the vehicle.
US11420613B1	Drivetrain with infinitely and electrically variable transmission capabilities Methods and systems are provided for an electric drive train of a hybrid electric vehicle (HEV). In one example, the electric drive train may include a four-node planetary gear set with a first motor coupled to a first input node, a second motor coupled to a second input node and an engine coupled to a third input node of the planetary gear set. The third node is positioned between the first and second input nodes. Torque delivered to each input node is summed at an output node of the four-node planetary gear set.
US11420612B2	Systems and methods for hybrid vehicle engine and motor torque coordination Methods and systems are provided for coordinating engine and motor torque in a hybrid vehicle system. The systems and methods use an engine torque command to obtain a motor torque command, and adjust the engine torque command based on an estimate of a time delay between commanded and actual motor torque prior to the engine command being sent to an engine controller. In this way, crankshaft torque accuracy may be improved.
US11420607B2	Brake control valve assembly An assembly may be provided that may include a valve body having a piston within a piston bore in the valve body, the piston bore including a valve chamber section and a brake pipe section such that a pressure differential between the valve chamber section and the brake pipe section moves the piston within the piston bore. The assembly may also include a slide valve seat coupled to the valve body. The slide valve seat may include a brake pipe port, an additional discharge channel pilot valve port, and at least one exhaust port, and a slide valve coupled to the piston and configured to move along the slide valve seat with the piston. The slide valve may be configured to move between at least a piloting position and an exhaust position to vary an exhaust rate of the brake pipe section and an exhaust rate of the valve chamber section during braking.
US11420606B2	Parking brake apparatus for vehicle A parking brake apparatus for a vehicle includes a pair of pressing units receiving power from a driving unit, and pressing a brake pad; and a load transmission unit installed between the pair of pressing units, connected to each of the pair of pressing units, and transmitting a pressing load of any one of the pair of pressing units to the other pressing unit, wherein the load transmission unit comprises a pair of ring gear sections, and the pair of ring gear sections are meshed with each other.
US11420604B2	Electric brake device A brake controller is provided with a positive efficiency operation limiter configured to provide a time for maintaining or decreasing a torque to be generated by a motor, such that a braking force generated by pressing between a brake rotor and friction pads does not decrease, while a braking force command value outputted from a braking force command section increases. For example, the limiter limits a ratio of a time for increasing the braking force, relative to a sum of the time for increasing the braking force and the time for maintaining or decreasing the braking force, to a predetermined value or less.
US11420601B2	Vehicle stoppage assistance apparatus A control device is provided with: a moving distance estimation unit that calculates an estimated value of a vehicle moving distance on the basis of a pulse signal inputted from a wheel speed sensor and a wheel dynamic load radius stored in a storage unit; a moving distance deriving unit that derives the calculated value of the vehicle moving distance on the basis of information acquired by monitoring systems; a vehicle stop position setting unit that sets a target vehicle stop position on the basis of the information acquired by the monitoring systems; a correction unit that corrects the target vehicle stop position on the basis of the calculated value of the moving distance and the estimated value of the moving distance; and a brake control unit that assists vehicle stoppage so as to stop the vehicle when it is determined that the vehicle has reached the target vehicle stop position on the basis of the vehicle moving distance calculated from a wheel rotation amount and the target vehicle stop position.
US11420599B2	Apparatus and systems for air-borne cleaning of surfaces There is provided a system and method of cleaning surfaces of an interior cabin space of a contamination comprising a microbial and viral load. The method includes the steps of sealing the interior cabin space and placing water, and a solid or gel pack, into a container and generating a vortex the container by rotating an impeller. The agitation causes the solid or gel pack to release a gaseous cleaning agent. An air-borne spray exiting from the container spreads throughout the interior cabin space to coat the surfaces to be cleaned within the interior cabin space. The cabin is maintained closed for an effective time period while the coating from the air-borne spray dwells on the surfaces to eliminate or substantially reduce the load of the contamination.
US11420595B2	Cleaning unit for cleaning foreign matter from a cover, in particular a cover of a transmitter/receiver window of a driving environment sensor, and device for sensing the environment and method A cleaning unit for cleaning foreign matter from a cover, in particular a cover of a transmitter/receiver window of an environment sensor, including at least one movable wiper blade, which is arranged so as to wipe off foreign matter such as water or dirt on the cover by movement along the cover. For this purpose, the wiper blade touches the cover for example with one or multiple rubber lips. The wiper blade is positioned in an inclined manner with respect to a direction of movement of the wiper blade and is thus movable in such a way that a force exerted by the moved wiper blade on the foreign matter has a component in the direction of the force of gravity. Also described is a related device for sensing the environment as well as a method for cleaning a cover.
US11420589B2	Systems and methods to localize a recreational trailer Trailer localizing systems and methods include a trailer to be coupled to the tow vehicle for towing and comprising solar panels and a tracking device communicatively coupled with a location determination device to transmit a current real time position of the trailer when active. The system is configured to determine whether the trailer is electronically connected to the tow vehicle, whether the solar panels are active upon a determination that the trailer is not electrically connected to the tow vehicle, activate the tracking device along with the location determination device upon a determination that the trailer is electronically connected to the tow vehicle, the plurality of solar panels are active, or both, generate an alert that the tracking device is active upon activation of the tracking device, and transmit the current real time position of the trailer with the alert to track the trailer.
US11420588B2	Wheelchair occupant restraint device A wheelchair occupant restraint device includes: a wheelchair retractor which is disposed in a vehicle cabin, and around which one end portion of a wheelchair belt member is wound; a wheelchair buckle which is disposed on the opposite side of a securing space for a wheelchair from the wheelchair retractor, and on which a wheelchair tongue plate attached to the other end portion of the wheelchair belt member is able to be mounted; an occupant retractor which is disposed on the opposite side of the securing space from the wheelchair retractor, and around which one end portion of an occupant belt member is wound; and an occupant buckle which is disposed on the opposite side of the securing space from the occupant retractor, and on which an occupant tongue plate attached to the other end portion of the occupant belt member is able to be mounted.
US11420584B2	Covering cap for an airbag module and airbag module having a covering cap of this type The invention relates to a cover cap (10) for an airbag module (12), especially for a driver airbag module, comprising a front panel (14) including an outer face (16) as well as an opposed inner face (18) which in the assembled state of the airbag module (12) faces a folded airbag (20), and an emblem (22) including two separate emblem elements (24, 26) fastened to the front panel (14), wherein the front panel (14) has a tear line (32) along which the cover cap (10) tears upon activation of the assembled airbag module (12), and wherein the tear line (32) extends between the two separate emblem elements (24, 26). Furthermore, the invention also includes an airbag module (12) comprising said cover cap (10).
US11420582B2	Attachment structure for side airbag device An attachment structure, for a side airbag device including an airbag that is to be deployed and inflated on a side of an occupant seated on a seat in a vehicle interior under pressure of a gas supplied from an inflator, includes an attachment member via which the airbag is attached inside the seat. The attachment member includes a support portion that supports the airbag before the airbag is deployed and inflated, an attachment portion that is attached inside the seat, and a guide portion that guides the airbag to a seat outer side at a time when the airbag is deployed and inflated. The guide portion is provided so as to correspond to a part of the airbag supported by the support portion.
US11420568B2	Display assembly for a means of transport A display assembly for a means of transport and a correspondingly equipped means of transport are disclosed. The display assembly includes a display unit, a bus subscriber and a housing comprising a data interface arranged at its outside, and a mechanical interface for fixing the housing in the means of transport, wherein the display unit and the bus subscriber are arranged in the housing and the bus subscriber is configured to be connected by information technology to a bus of the means of transport via the data interface.
US11420564B2	Configurable storage systems Configurable and reconfigurable stowage systems for vehicle storage areas for a vehicles including cars, truck, boats, recreation vehicles, snowmobiles, all-terrain vehicles and the like are disclosed. In some embodiments, vehicle storage areas include saddle bags and trunks of vehicles. In some embodiments the stowage systems include a contourable reconfigurable liner that includes configuration features and partitioning devices.
US11420563B2	Running boards and vehicles The present disclosure relates to a running board and a vehicle comprising the same. The running board includes an intermediate connector, a first running board body, and the second running board body. The intermediate connector includes a first rotating shaft, a second rotating shaft, a first mounting member, and a second mounting member. The first rotating shaft is connected to the second rotating shaft. The first rotating shaft is inserted into the first mounting member, and the first mounting member rotates about the first rotating shaft. The second rotating shaft is inserted into the second mounting member, and the second mounting member rotates about the second rotating shaft. The first running board body and the second running board body are foldable side-to-side through the intermediate connector.
US11420561B2	Lateral image processing apparatus and method of mirrorless car The present invention relates to a lateral image processing method, and the method includes recognizing areas in which amounts of image change are different from each other in an image captured by a camera; determining whether a car is in a driving state; and converting an image in one area in which an amount of image change is different according to the driving state of the car.
US11420558B2	Interior trim part of motor vehicle with thin-film display device The disclosure relates to an interior trim part of a motor vehicle which comprises: a shaped part made of glass or a glass-like material which is arranged on the side of the interior trim part facing the interior of the motor vehicle, a thin-film display device which as seen from the motor vehicle interior is arranged behind the shaped part or is integrated therein, and a control device for activating the thin-film display device, so that the latter transmits an image through the shaped part to the interior of the motor vehicle.
US11420557B2	Light converting device with confined light converter A light converting device comprising: a light converter with a light entrance surface and a light emission surface, wherein the light converter is arranged to convert laser light scanned over the light entrance surface to converted light, wherein a peak emission wavelength of the converted light is in a longer wavelength range than a laser peak emission wavelength of the laser light, a confinement structure enclosing the light converter, wherein the confinement structure is arranged to preserve a geometric shape of the light converter in case of a mechanical failure of the light converter. A laser-based light source comprising such a light converting device and a vehicle headlight comprising such a laser-based light source.
US11420556B2	Directional speed and distance sensor A method of using a directional sensor for the purposes of detecting the presence of a vehicle or an object within a zone of interest on a roadway or in a parking space. The method comprises the following steps: transmitting a microwave transmit pulse of less than 5 feet; radiating the transmitted pulse by a directional antenna system; receiving received pulses by an adjustable receive window; integrating or combining signals from multiple received pulses; amplifying and filtering the integrated receive signal; digitizing the combined signal; comparing the digitized signal to at least one preset or dynamically computed threshold values to determine the presence or absence of an object in the field of view of the sensor; and providing at least one pulse generator with rise and fall times of less than 3 ns each and capable of generating pulses less than 10 ns in duration.
US11420555B2	Non-visual notifications for autonomous vehicles An audio notification system for an autonomous vehicle (AV) determines that the AV is within range of a user and emits a sound though a speaker of the AV to notify that the user that the vehicle has arrived. The audio notification system may include a sensor for sensing that the user has accessed the AV, and turns off the sound in response to the user accessing the AV. The audio notification may be generated according to one or more audio options, e.g., volume, pitch, or audio pattern.
US11420551B2	Light emitting device A light emitting device for a leaning vehicle, including a pair of cornering lamps, including a first cornering lamp and a second cornering lamp, that emit light to form a single left-front light emission area and a single right-front light emission area, and a control device that controls light emission by the pair of cornering lamps based on a lean angle of the vehicle body. The control device is configured to cause a first quantity of light and a second quantity of light, which are respectively a quality of light outputted from the at least one light source included in the first cornering lamp and in the second cornering lamp, respectively, to vary in accordance with the lean angle of the vehicle body, such that each of the single left-front light emission area and the single right-front light emission area becomes larger as the lean angle of the vehicle body increases.
US11420549B1	Exhaust component with illumination One embodiment of exhaust component (30) contains a shield (40). The shield being opaque allows indefinite designs to be cut out. These designs are illuminated by illumination assembly (36), which enhances cutouts (44), thereby allowing them to remain visible under all conditions. Another embodiment of the exhaust component without the shield contains illumination modules (58). These modules illuminate the exhaust component's mouth (32) through base (22) or outer wall (34), and this allows the shape of the exhaust component to be the design feature. The illumination of the mouth both enhances the shape and allows it to remain visible under all conditions. These embodiments can occur alone or together for both maximal design enhancement and additional visibility of the vehicle thereby increasing safety.
US11420544B2	Cooling fan and seat cooling device comprising same Provided is a cooling fan including: a fan housing having an air inlet formed on a front surface thereof and through which air flows and an air outlet formed at a side surface of the fan housing and through which air is discharged; and an impeller mounted inside the fan housing to introduce air in an axial direction thereof and discharge air in a radial direction thereof, wherein a bypass passage is formed at an edge of the air inlet so that air flowing in a direction opposite to the air outlet can be discharged to the outside. At high power of a cooling fan, backward-flow air is discharged to the outside to minimize noise and improve blowing efficiency.
US11420539B2	Vehicle seat with inclining backrest feature The invention relates to a vehicle seat comprising a backrest element having a first contact surface which is arranged within a first imaginary plane, and a seat element having a second contact surface which is arranged within a second imaginary plane which is defined by a longitudinal axis and a width axis of the vehicle seat, wherein the first imaginary plane and the second imaginary plane intersect in an intersecting axis, wherein the backrest element is pivotable relative to the seat element about a rotational axis, wherein an inclination angle of the backrest element extends between the first imaginary plane and a central axis which runs perpendicularly to the second imaginary plane, wherein, in a first position of the backrest element, a distance along the longitudinal axis between the rotational axis and the intersecting axis is at least 60 mm, wherein, in the first position of the backrest element, the inclination angle is substantially 10°.
US11420533B2	Battery system A battery system for an electric vehicle, including: a high voltage (HV) battery subsystem including a battery cell stack with battery cells electrically connected between stack nodes; a low voltage (LV) battery subsystem including a LV battery and a supply node connectFed to the LV battery; a DC/DC converter with a primary coil in the HV battery subsystem and a secondary coil in the LV battery subsystem, wherein the primary coil is connected to one of the stack nodes via a switch. A threshold signal indicative of a voltage at the supply node may be generated in the LV battery subsystem and may be transmitted to the HV battery system. A state of the switch may be controlled based on the threshold signal.
US11420527B2	Electric vehicle charging system with battery temperature control A method of charging a battery of an electric vehicle includes: determining that a battery temperature of a secondary battery is below a predetermined lower temperature limit suitable for charging the secondary battery at a high charging power greater than 18 kW; externally applying, by contactless energy transfer means, electromagnetic energy to an energy conversion module of the electric vehicle; converting the electromagnetic energy to heat and heating the secondary battery to a temperature above the lower temperature limit; and charging the secondary battery at the high charging power while maintaining the battery temperature between the lower temperature limit and an upper temperature limit at least in part by controlling a magnitude of the electromagnetic energy.
US11420526B2	Charge controller, charging system, and vehicle A processor included in a server acquires, by a weather information acquisition unit, weather information related to rainfall in a region where an external charging of a vehicle is performed. The processor also acquires flooding information indicative of prediction of flood damage to the region from a flooding information DB included in a storage device. If the vehicle is determined, based on the acquired weather information and flooding information, as likely to be inundated with water while the vehicle is stationary in the charging station, the processor transmits to the vehicle a stop instruction for stopping the external charging. The vehicle stops the external charging if the vehicle receives the stop instruction for stopping the external charging from the server.
US11420522B1	Vehicle activation systems and methods for electric vehicles Methods and systems for activating electric vehicles are provided. One method includes, in response to a first command to activate the vehicle, transitioning the vehicle from an inactive state to a wake state where a controller of the vehicle is activated and the vehicle is prevented from being propelled by an electric motor of the vehicle. The method also includes, in response to receiving a second command to activate the vehicle after receiving the first command, transitioning the vehicle from the wake state to a ready state where the vehicle is permitted to be propelled by the electric motor.
US11420520B2	Decorative component A decorative component for an interior space of a motor vehicle includes a display panel configured to cover a display element and/or constituting a display element. The decorative component further includes a decorative element, adjoining the display panel, configured to provide a visually and haptically perceptible decorative surface. The haptic and/or visual perception of the decorative surface is different than the haptic and/or visual perception of a panel surface of the display panel. The display panel overlaps the decorative element in an overlapping region and a material thickness of the display panel is designed such that it becomes monotonously thinner toward the decorative element in the overlapping region.
US11420514B2	Multispeed transaxle with sprung powertrain mounting and methods therefor Vehicles, powertrains for vehicles, and methods of mounting powertrains to chassis of vehicles are disclosed herein. A vehicle includes a chassis, a plurality of wheels, and a powertrain. The chassis extends along a longitudinal axis from a first end to a second end arranged opposite the first end. The plurality of wheels are coupled to the chassis between the first end and the second end and configured for rotation about a rotational axis. The powertrain is mounted to the chassis transverse to the longitudinal axis between the first end and the second end. The powertrain is configured to drive rotation of the plurality of wheels about the rotational axis in use of the vehicle.
US11420510B2	Battery mounted vehicle A battery-mounted vehicle according to an example of the present disclosure accommodates one or a plurality of batteries under the floor panel. The battery-mounted vehicle includes a battery-cooler unit, a condenser, a refrigerant liquid pipe, and a plurality of refrigerant gas pipes. The refrigerant liquid pipe guides the refrigerant liquid from the condenser to the battery-cooler unit. The refrigerant gas pipe guides the refrigerant gas generated by vaporization of the refrigerant liquid from the battery-cooler unit to the condenser. The plurality of refrigerant gas pipes include a first and a second refrigerant gas pipes. The first refrigerant gas pipe extends in a first direction from the battery-cooler unit to the condenser, and connects the condenser and the battery-cooler unit. The second refrigerant gas pipe extends from the battery-cooler unit in a second direction opposite to the first direction, and is connected to the condenser by being bended or curved.
US11420507B2	Power train support structure for vehicle A power train support structure includes a first front side frame disposed on one of left and right sides of a power train; a second front side frame disposed on the other of the left and right sides of the power train, and being greatly away from the power train with respect to the first front side frame; a mounting bracket having one of left and right ends connected to the power train; and a connecting member for connecting the mounting bracket and the second front side frame. The mounting bracket includes a front fixing portion and a rear fixing portion to be fixed to the power train. A strength of the front fixing portion and the rear fixing portion is set to such a strength that the rear fixing portion is broken by a collision load from a front side, and the front fixing portion is not broken.
US11420506B2	Modular and collapsible vehicle frame for attaching to a vehicle body Apparatus and associated methods relate to a modular vehicle roof frame with at least two support members having at an upper end at least one coupling member through which the support member is axially assembled and releasably coupled to a plurality of top frame members such that each top frame member is releasably coupled to a plurality of support members. In an illustrative example, when the frame is assembled the support members may be substantially vertical and the top frame members may be substantially horizontal. When the frame is coupled to a vehicle the coupling members may, for example, be oriented substantially parallel to a longitudinal axis of the vehicle. The frame may be assembled, for example, by alternately assembling top frame members and support members. Various embodiments may advantageously allow a disassembled frame to be stored within a small sized container suitable for various ground shipping services.
US11420501B1	Cabin air filtering and dehumidifying apparatus A vehicle cabin air filter apparatus for dehumidifying air within its vicinity prior to filtering particulates from air that flows through it along the normal path of flow from the HVAC system into the vehicle passenger cabin.
US11420493B2	Space frame front lower suspension connection A front lower suspension connection for a space frame comprises a U-shaped base and upper suspension control arm support sections on the U-shaped base. The U-shaped base can have a cross-beam section and suspension column support beam sections positioned at opposite ends of the cross-beam section, where each suspension column support beam section may include lower suspension control arm pivot joint supports located at opposite ends of the suspension column support beam sections. Each upper suspension control arm support section can have a first support column and a second support column spaced from the first support column, where the first support column may include a first upper suspension control arm pivot joint support, and the second support column may include a second upper suspension control arm pivot joint support and a front mounting surface. A rear mounting may be provided on a rear surface of the front lower suspension connection.
US11420489B2	Height adjustable implement mount for single-point hitch equipped vehicles An implement mount for height adjustable mounting of an implement to a vehicle. The mount features a hitch coupler for mating with a single-point hitch of the vehicle to reach longitudinally therefrom, and a guide frame defining at least one guide slot lying transverse to the longitudinal direction of the hitch coupler in an upright orientation. At least one link arm is pivotally supported on the hitch coupler, and an implement carrier is coupled to the link arm proximate a rear end thereof. A follower arrangement is engaged between the link arm and the guide slot to constrain movement of the implement carrier to movement along the guide slot. Pivotal movement of the link arm in a first direction lifts the implement carrier along the guide slot, while pivotal moment in a second direction lowers the implement carrier along the guide slot.
US11420487B2	Method and apparatus for mounting a tire sensor A tire sensor dock for installing an electronic tire sensor module on the inner surface of a tire, including a base portion with an upper side and an underside, the underside configured for affixation on the inner surface of a pneumatic tire, and a body portion integrally formed on the upper side and configured to receive and securely capture a tire sensor in a fixed position and unchanging orientation relative to the tire sensor dock. The tire dock may include an energy generator which converts tire kinetic energy into electrical current provided to the tire sensor module.
US11420486B2	Wheel release detection A method for determining an item of fastening information of a wheel of a motor vehicle, wherein rotational movements of the wheel are detected by at least one sensor. The sensor provides a wheel speed signal to an electronic control unit, which determines the fastening information from the wheel speed signal. A first time-frequency transformation of the wheel speed signal is carried out, whereby a first transformation signal is generated, after which a second time-frequency transformation of the first transformation signal is carried out. A second transformation signal is generated, in particular after which a first fastening parameter is obtained from the second transformation signal, after which the fastening information is calculated/determined as a function of the second transformation signal and/or the first fastening parameter.
US11420478B2	Tyre A tyre includes a tread portion including a groove bottom surface and a plurality of blocks protruding from the groove bottom surface. The plurality of blocks includes one or more multi-height blocks. Each multi-height block includes a first block portion having a first height from the groove bottom surface, a second block portion having a second height from the groove bottom surface, a third block portion having a third height from the groove bottom surface, and a block groove to define the first block portion, the second block portion and the third block portion. The second height is higher than the first height, and the third height is higher than the second height.
US11420473B2	Bicycle and tire structure A tire structure disposed at a rim is provided. The tire structure includes a tire body, a flexible sealing member and a nozzle. The tire body is ring-shaped and includes a groove and two beads. The flexible sealing member is connected to the tire body to form an inflating space with the groove, and the flexible sealing member includes a through hole. The nozzle is disposed at the flexible sealing member. The nozzle includes a base and a valve stem. The base includes a screw hole and is disposed at a far side of the flexible sealing member. The screw hole corresponds to the through hole. The valve stem includes a fastening end and an inflating channel. The fastening end is configured to insert into the screw hole, and the inflating channel is configured to allow the gas to pass therethrough.
US11420470B2	Wheel bearing A wheel bearing including at least one inner ring. In order to achieve a greater efficiency, the inner ring forms an outer ring of a tripod constant-velocity joint. The wheel bearing may further include an outer ring and two rolling-element rows including a first rolling-element row and a second rolling-element row.
US11420468B2	Wheel hub and bearing assembly packaging A packaging system having an outboard guard and an outboard retainer cap. The outboard guard includes an outboard guard opening having a hole through the planform of the outboard guard, an engagement portion having an annular surface radially surrounding the outboard guard opening, an outboard bearing protector portion having an annular surface radially surrounding the engagement portion of the outboard guard, and an outer rim having an annular surface radially surrounding the outboard bearing protector portion. The outboard retainer cap is configured to be removably affixed to the outboard guard and includes an outboard alignment protrusion having a circular surface, an engagement portion having an annular surface radially surrounding the outboard alignment protrusion, and a retaining flange having an annular surface radially surrounding the engagement portion of the outboard retainer cap.
US11420467B2	Low-friction sealing device for wheel hub assemblies connected to constant-velocity joints A sealing device for wheel hubs connected to constant-velocity joints including a first sealing assembly arranged between inner and outer rings of the wheel hub, and a second sealing assembly mounted on the inner ring and straddling the wheel hub and an outer ring of the constant-velocity joint. The first sealing assembly has a signal generating element having an annular insert mounted externally on a shield facing the constant-velocity joint and extending axially projecting above part of an annular step formed, on the same side as the constant-velocity joint, on a radially outer side surface of the inner ring, in a position immediately adjacent to the sleeve portion of the first shield. The second sealing assembly includes a tubular support keyed onto the inner ring by its first end on the outside edge folded in the manner of an L and shaped to engage inside the annular insert.
US11420464B2	Photosensitive printing form for a flexographic printing method comprising visible and non-printable information, and method for preparing such a printing form A photosensitive flexographic printing form, and process for manufacturing the same. The printing form includes a base, a first series of relief patterns having a first elevation with respect to the base in an image area of the base, and a second series of relief patterns having one or more elevations lower than the first elevation and located outside of the image area.
US11420463B2	Ink jet recording method and ink jet recording apparatus Provided is an ink jet recording method using an ink jet recording apparatus having an ink jet head, the method including: a colored ink adhesion step of discharging an aqueous colored ink composition containing a coloring material from an ink jet head to adhere to a recording medium; and a clear ink adhesion step of discharging an aqueous clear ink composition from an ink jet head to adhere to the recording medium, in which the aqueous clear ink composition contains wax particles, the ink jet recording apparatus has a circulation path for circulating the aqueous clear ink composition, and in the clear ink adhesion step, the aqueous clear ink composition circulated in the circulation path is discharged.
US11420453B2	Conveyance device and liquid discharge apparatus A conveyance device includes a support having a support face configured to support a conveyed object and a fluid introduction device disposed outside the support. The fluid introduction device is configured to introduce a fluid between the support face of the support and the conveyed object, to form a fluid layer for floating the conveyed object. The conveyance device further includes a conveyor configured to convey the conveyed object being floating from the support via the fluid layer.
US11420448B2	Thermal head control device, thermal printer, and thermal head control method A thermal head control device includes: a printing rate calculation range determination unit configured to determine, as a printing rate calculation range, a range from a left-end energization dot to a right-end energization dot among energization dots present in printing data corresponding to heating elements to be controlled among a plurality of heating elements included in a thermal head; a printing rate calculation unit configured to calculate a printing rate of the printing rate calculation range determined by the printing rate calculation range determination unit; an energizing time calculation unit configured to calculate an energizing time for which a current is caused to flow through the heating elements based on the printing rate calculated by the printing rate calculation unit; and an output unit configured to output a control signal for driving the heating elements to be controlled of the thermal head, based on the calculated energizing time.
US11420446B2	Liquid discharge device A liquid discharge device includes: a tank including a second liquid chamber connectable to a cartridge having a first liquid chamber storing a liquid; a head; and a controller configured to: discharge ink from the head based on a recording instruction; receive a second signal from a liquid level sensor when a position of the liquid level in the second liquid chamber is less than a predetermined position after the ink is discharged based on the recording instruction; after receiving the second signal, determine whether the cartridge is installed in an installation case; based on determining that the cartridge is installed in the installation case after receiving the second signal from the liquid level sensor, accept a maintenance process; and based on receiving the first signal from the liquid level sensor, perform the maintenance process.
US11420445B2	Quick connect assembly for fluid and electrical connections A quick connect assembly includes a connector housing and fluid connectors that fluidly couple an ink assembly and a print assembly. The quick connect assembly also includes conductive connectors that conductively couple hardware circuitry in the ink assembly with hardware circuitry in the print assembly. First and second portions of the connector housing mate with each other to couple the fluid connectors and to couple the conductive connectors. The first and second housing portions mate with each other by rotating the first housing portion and/or the second housing portion relative to the other of the first housing portion and/or the second housing portion.
US11420440B2	Inkjet head and method for producing same An inkjet head having a metal wiring on a board in an ink flow path or an ink tank includes a base layer and an organic protective layer on the metal wiring, arranged in an order of the metal wiring, the base layer, and the organic protective layer. The base layer has an interface that is in contact with the metal wiring and that includes at least one of a metal oxide and a metal nitride. The base layer has an interface that is in contact with the organic protective layer and that includes at least one of a silicon oxide and a silicon nitride.
US11420438B2	Liquid ejecting apparatus, drive circuit, and circuit substrate A liquid ejecting apparatus includes a print head including a drive element; a first circuit substrate electrically coupled to the print head; a second circuit substrate electrically coupled to the first circuit substrate; and a fixing portion that fixes the second circuit substrate to the first circuit substrate, wherein the first circuit substrate includes a coupling terminal electrically coupled to the print head, and a first substrate on which the coupling terminal is provided, wherein the second circuit substrate includes a drive signal output circuit that outputs a drive signal for driving the drive element and a second substrate on which the drive signal output circuit is provided, and wherein the fixing portion also serves as a output terminal through which the drive signal is output to the first circuit substrate.
US11420432B1	Method and apparatus for adhesive dispensing A method of dispensing an adhesive on a substrate includes flowing an extrudate of the adhesive through a flow control valve and an application nozzle, and introducing a non-adhesive fluid into the extrudate within the flow control valve upstream from a distal end of the application nozzle such that the non-adhesive fluid interrupts a boundary layer of the extrudate and a non-contact cut of the extrudate is provided. The non-adhesive fluid can be air that forms a bubble in the extrudate of the adhesive flowing through the application nozzle and adhesive dispensed onto the substrate is free of a string and/or a teardrop.
US11420422B2	Switchable optical device and method for manufacturing of a switchable optical device A switchable optical device is provided having a first substrate (11), a second substrate (12) and a seal (114). The two substrates (11, 12) and the seal (114) are arranged such that a cell having a cell gap is formed and a switchable medium (10) is located inside the cell gap. The first substrate (11) has a first transparent electrode (21) and the second substrate (12) has a second transparent electrode (22). The electrodes (21, 22) are facing towards the cell gap. The two substrates (11, 12) are arranged such that the first substrate (11) has a first region (71) adjacent to a first edge (41) of the first substrate (11) which does not overlap with the second substrate (12) and the second substrate (12) has a second region (72) which does not overlap with the first substrate (11). A first electrically conducting busbar (31) is arranged in the first region (71) and a second electrically conducting busbar (32) is arranged in the second region (72). A first terminal is electrically connected to the first busbar (31) and a second terminal is electrically connected to the second busbar (32). The first substrate (11) and the second substrate (12) each have an edge deletion (116) in which the respective transparent electrode (21, 22) is removed. The edge deletion (116) is complete on the edges non-adjacent to a busbar (31, 32) and there is no edge deletion or only partial edge deletion on edges adjacent to a busbar (31, 32).Further aspects of the invention relate to a method for designing a switchable optical device, a method for driving a switchable optical device, a method for manufacturing a switchable optical device and a system comprising a switchable optical device and a controller for driving the switchable optical device.
US11420420B2	Composite material steel sheet A composite material steel sheet comprises: at least one steel sheet, and a resin-impregnated paper composite layer, wherein the resin-impregnated paper composite layer may comprise stacked sheets of paper, and impregnated resin provide adhesion between the sheets of paper in contact with each other.
US11420411B2	Electro-active polymer device and method for manufacturing such a device Disclosed is a method for manufacturing an electro-active polymer layer structure including an elastomer layer and at least one electrode layer that is arranged on a first surface of the dielectric elastomer layer, the method including: applying a layer of conductive material on the first surface of the elastomer layer. The layer of conductive material consists of agglomerated graphene based nanoplatelets, having a flattened shape between two main surfaces parallel to the graphene molecular lattice plane. The method further includes: obtaining a texture of the nanoplatelets in the applied layer by orienting the nanoplatelets on the first surface of the elastomer layer with the main surfaces of the nanoplatelets being parallel with the first surface of the elastomer layer, such that the graphene molecular lattice plane of the nanoplatelets is parallel to the first surface of the elastomer layer.
US11420406B2	Method and apparatus for manufacturing a tyre tread and a tyre A method of manufacturing an agricultural tyre (1) with deep cross-lugs (6), comprising the steps of: (a) proving a tyre case (2) and tread belts (3); (b) applying rubber blocks (206) onto tread belts (3), each of such rubber blocks (206) being arranged to make a respective lug (6) of the final tread (4); (c) winding a rubber ribbon (200) above said rubber blocks (206) so as to completely enclose said rubber blocks (206); (d) curing the rubber blocks (206) together with the wound ribbon (200) in a curing mould (105) negatively reproducing a desired pattern of the tread (4).
US11420398B2	Resonant reactive support structure for additive manufacturing process A system for separating support structure from a three-dimensional (3D)-printed component integrally printed with the support structure during an additive manufacturing (AM) process includes one or more transducers, indexing features configured to engage the transducer(s) and position the transducer(s) in contact with the support structure, and an electronic control unit (ECU). The ECU activates the transducer(s) which then vibrate at a predetermined resonant frequency of the support structure until the support structure fractures. A method includes engaging a transducer with an indexing feature, positioning the indexing feature with respect to the support structure such that the transducer is in contact with the support structure, and activating the transducer during a post-processing stage of the AM process, via the ECU, to cause the transducer to vibrate at the predetermined resonant frequency until the support structure fractures or breaks.
US11420394B2	3D printing system A 3D printing system comprises a 3D printing arrangement operable to print a 3D object, a processing unit operable to analyse images captured by an infra-red camera to detect the state of the object being printed, a substrate upon which the 3D printed object is adhered during the 3D printing process; and an infra-red light source arranged to illuminate the substrate in such a manner so as to cause total internal reflection of the infra-red light to occur in the substrate when the 3D object is not adhered to the substrate, wherein the infra-red camera is arranged to view the surface of the substrate opposite to that which the 3D object is printed upon so that the camera may capture images of the 3D object when it is correctly adhered to the substrate; and the processing unit is operable to analyses the captured images to detect whether the 3D object is correctly adhered to the substrate.
US11420393B2	Support fabrication techniques in three-dimensional printing The strength of a bond between two adjacent layers of a three-dimensional print is weakened by initiating fabrication of a top layer at a height greater than the processing height for the print. This technique may be used in particular at the interface between a raft or other support and an object being fabricated, after which the printing process may return to a regular process height for additional layers used to fabricate the remainder of the object.
US11420392B2	Transport unit and preparation of a three-dimensional component A transport unit for transporting an additively manufactured three-dimensional component including a transfer interface which can be closed in a substantially gastight manner for the three-dimensional component and/or a container containing the three-dimensional component and/or a platform carrying the three-dimensional component, which transfer interface is configured and disposed so that it cooperates with an output interface of an additive manufacturing machine which has manufactured the three-dimensional component within the framework of a component transfer as intended and when a connection is made as intended between the transfer interface and output interface a substantially gastight connection can be produced, and a storage chamber for storing the component and/or the container and/or the platform in a substantially gastight sealed state towards the outside.
US11420391B2	Cleaning mechanism for 3D printer A novel machine tool featuring a rotary tool changer is disclosed. In one embodiment, the tool changer is pre-tensioned, preferably by a counterweight, to improve repeatability when shifting from one tool to another. In another embodiment, the machine tool is principally a 3D printer, and features a novel cleaning mechanism that improves print quality, especially when printing elastomeric materials. In another embodiment, the machine tool features a rubbing tool that is heated and passed over the surface of a workpiece to improve the smoothness and precision of the workpiece.
US11420380B2	Shaping device and production method for shaped object In a shaping device, a sheet that distends due to being irradiated with electromagnetic waves is placed a conveyor belt. An irradiator irradiates the sheet placed on and conveyed by the conveyor belt with electromagnetic waves. At least one heater heats the conveyor belt.
US11420379B2	Method for hot-forming a thermoplastic material and implementation facility A method for shaping a preform made from thermoplastic material, and a facility for implementing the method, comprising the following steps: a) providing a preform made from thermoplastic material having a surface; b) supplying thermal energy to the preform by radiation in such a way as to make it ductile; and c) shaping the ductile preform inside a forming mould. Step b) further involves simultaneously spraying a gaseous fluid onto the surface of the preform in order to preserve the surface.
US11420373B2	Preform device for positioning extruded rubber mixtures, and extruder mold system comprising the preform device for molding extruded rubber mixtures into a complete rubber element, and corresponding extruder system The invention relates to a preform device for positioning extruded rubber mixtures, characterized in that the preform device consists of an inlet module (2) and an outlet module (3), wherein both the inlet module (2) and the outlet module (3) each have a base surface (11, 12) and a contact face (19, 21) opposite the base surface (11, 12, 13), and wherein the surface of the contact face (19, 21) of the inlet module (2) is smaller than the surface of the base surface (11, 12) of the inlet module (2). The invention also relates to an extruder mold system for molding extruded rubber mixtures into a complete rubber element (40), having the preform device and at least one final forming device, and to a corresponding extruder system (22).
US11420367B2	Foam molding process by modifying amorphous PLA A process of microcellular foam molding an article includes using a modifier to modify properties of amorphous PLA, pouring the modified amorphous PLA into a high pressure vessel, dissolving an SCF in the high pressure vessel to impregnate the modified amorphous PLA in the high pressure vessel which is configured to allow the SCF to effuse through, forming foamed pellets, conveying the foamed pellets to a mold in a second vessel filled with water or oil, heating the second vessel, and cooling the second vessel until a foamed article is finished in the mold.
US11420365B2	Method for producing foamed particle molded article provided with skin A method for producing a foamed particle molded article provided with a skin, includes: forming a hollow molded article; filling a hollow part of the hollow molded article with polypropylene-based resin foamed particles; and heating and fusing the particles to each other. A melt elongation at 190° C. of the polypropylene-based resin forming the hollow molded article is 100 m/min or more. A half-crystallization time at 100° C. of the polypropylene-based resin is between 25 to 80 seconds. In heat flux differential scanning calorimetry, a melting peak temperature of the polypropylene-based resin is between 130 to 155° C., a partial heat of fusion at 140° C. or more of the polypropylene-based resin is between 20 to 50 J/g, and a ratio of the partial heat of fusion of the polypropylene-based resin to the total (partial heat of fusion/total heat of fusion) is between 0.2 to 0.8.
US11420362B2	Mechanisms to automate removal of aligner from mold Embodiments relate to automating removal of an untrimmed shell from a mold. In one embodiment, a shell removal device includes a body and a platform disposed within the body. The platform is configured to secure a mold that has an untrimmed shell formed over the mold. The shell removal device further includes a cover configured to secure the untrimmed shell to an upper surface of one or more sidewalls of the body and provide a seal between a lower surface of the untrimmed shell and the upper surface of the one or more sidewalls of the body. The shell removal device may include a media inlet in the body to permit pressurized media into the interior of the body to cause a pressure differential between an upper surface of the untrimmed shell and the lower surface of the untrimmed shell to cause the untrimmed shell to release from the mold.
US11420360B2	Latching mechanism for suppository mold A latching mechanism suitable for suppository molds, where the latching mechanism is designed to assist the separation of mold when the latch is released. In embodiments, the latching mechanism has a lever portion on a first mold half and a catch portion on a second mold half. The lever portion is configured to impinge upon the catch portion to provide a force to bias the first mold half away from the second mold half. Other embodiments include methods of utilizing such a catching mechanism with a suppository mold.
US11420356B2	Splitter profiler In various embodiments, a splitter profiler apparatus may include at least one profiler head and at least one circular saw mounted to a common arbor. The circular saw may be mounted to a saw arm, and the saw arm may be coupled with an actuator that is selectively operable to move the circular saw along the arbor. The circular saw may be used in a profiling position, in which the circular saw and profiler head are in close proximity, such that the profiler head and circular saw function collectively to form a sideboard edge with a sawn finish. The circular saw may also be used in a splitting position, in which the circular saw is at a distance from the profiler, to divide the sideboard into narrower sideboards before the sideboards are sawn from the primary workpiece. Corresponding methods and systems are also described herein.
US11420355B2	Multi-pack container and machine for manufacturing the same The invention relates to a multi-pack container which defines a series of containers (11) formed in a plastic sheet (L) that comprises at least a layer of PET (polyethylene terephthalate), and in which said containers (11) are joined by bridges (12), provided with a pre-cut upper line (13) and a pre-cut lower line (14) for breaking the bridge (12). The pre-cut upper line (13) and a pre-cut lower line (14) are arranged parallel to one another, laterally separated in a horizontal direction and vertically separated to prevent heating by compression and a variation of the properties of the PET layer, allowing for clean breakage of the bridge by rotating the containers with respect to said pre-cut upper and lower lines. The invention also comprises a machine for manufacturing the multi-pack container.
US11420354B2	Film cutting jig and method of mounting film Object: To provide a film cutting jig and a method of mounting a film that can easily mount a film that not only covers a roof of an object but also wraps around to the sidewalls of the object. Resolution means: The present invention provides a film cutting jig used when cutting a film to cover at least a roof of an object that includes a sidewall and the roof, the film cutting jig including: a main jig body that is to be attached to the object to continuously surround a covered region that includes the roof and at least a portion of a top edge side of the sidewall when the object is viewed from above, wherein a guide for guiding a cutting tool to cut the film is formed in the main jig body, and wherein the guide is formed to continuously surround the covered region when the object is viewed from above.
US11420350B2	Shaving cartridge with enhanced rinsability The present invention relates to razor cartridge with a multifunctional seat that is attachable to a handle, plurality of blades without the spacers and a multifunctional cap obviating the use of spacers in between blades. The multifunctional seat provided with protrusions/selective seat and multifunctional cap with corresponding provisions to hold respective blade on the seat enables to dispose plurality of blades parallelly with respect to each other without the use of spacers and yet holding the blades rigidly in their predisposed positions during shaving and providing flushing channels for cleaning of the shaving debris during rinsing of the cartridge after shaving.
US11420348B2	Rotatable body hair clipper A rotatable body hair clipper is disclosed including a handle, a first cutting portion, a second cutting portion comprising a holding portion comprising a first tapered surface and a second tapered surface. The handle includes a handle main-body and a protrusion combination portion comprising a fastening portion comprising a first inclination surface and a second inclination surface. The protrusion combination portion comprises at least one slit such that when the second cutting portion is separated from the protrusion combination portion, the first tapered surface is brought into close contact with the second inclination surface and a part of the protrusion combination portion is elastically transformed inward in the radial direction when the second cutting portion is combined with the protrusion combination portion. The second tapered surface is brought into close contact with the first inclination surface and the part thereof returns to an original position thereof.
US11420347B2	Trimmer blade and body hair cutting device Trimmer blade includes stationary blade that includes a plurality of first unit blades, and movable blade that includes a plurality of second unit blades and slides relative to stationary blade. A leading end of first unit blade includes projection that projects from first sliding surface of first unit blade. A leading end face of one of the plurality of second unit blades touches projection.
US11420344B2	Smooth surfaced flexible and stretchable skin for covering robotic arms in restaurant and food preparation applications A sleeve apparatus for protecting a robotic kitchen arm from contamination. The sleeve includes a proximal end, a distal end, a passageway extending from the proximal end to the distal end, and an exterior surface. The passageway has an effective diameter less than the effective diameter of the robotic kitchen arm such that the exterior surface of the sleeve apparatus is substantially fold-free when the robotic arm is in the extended configuration. Methods of cleaning a robotic kitchen arm are also described.
US11420343B2	Parallel link robot A parallel link robot includes a main body, a number of driving mechanisms provided in the main body, a number of link units each having one end connected to corresponding one of the plurality of driving mechanisms, a movable plate disposed beneath the main body, and supported by the other ends of the number of link units, and an oil tray placed adjacently to the lower surface of the main body, where the oil tray is detachably attached to the main body.
US11420341B2	Five-degree-of-freedom parallel mechanism and its extended equipment A five-degree-of-freedom parallel mechanism and a series-parallel multi-degree-of-freedom equipment having the parallel mechanism are disclosed, and can machine complex components and parts as well as large structural parts and implement multi-degree-of-freedom numerical control machining, such as offsite maintenance of large equipment. The parallel mechanism includes: a rack; a movable platform; a first chain connected with the rack by at least two revolute pairs with axes intersecting with each other perpendicularly, and connected with the movable platform by at least two revolute pairs with axes intersecting with one another perpendicularly; a second chain having the same structure as the first chain; and a third chain including a main branch chain and two auxiliary branch chains, wherein the first chain, the second chain, and the third chain are separately connected between the rack and the movable platform.
US11420337B2	Transport apparatus A substrate transport apparatus for transporting substrates, the substrate transport apparatus including a frame, at least one transfer arm connected to the frame, at least one end effector mounted to the at least one transfer arm and at least one substrate support pad disposed on the at least one end effector, the at least one substrate support pad has a configuration that effects increased friction force, resulting from an increased friction coefficient, in at least one predetermined direction.
US11420335B2	Information processing apparatus, information processing method, and information processing system There is provided an information processing apparatus to estimate a position of a distal end of a movable unit with a reduced processing load, the information processing including a position computer that computes, on the basis of first positional information obtained from reading of a projected marker by a first visual sensor and second positional information including positional information obtained from reading of the marker by a second visual sensor that moves relative to the first visual sensor, a position of a movable unit in which the second visual sensor is disposed. This makes it possible to estimate the position of the distal end of the movable unit with a reduced processing load.
US11420334B2	Candidate six dimensional pose hypothesis selection The present disclosure relates to methods, devices, and systems for selecting a candidate six dimensional pose hypothesis from among a plurality of six dimensional pose hypotheses. For example, the systems, devices, and methods described herein may be used to quickly, accurately, and precisely select a candidate six dimensional pose hypothesis from among a plurality of six dimensional pose hypotheses so that the selected candidate six dimensional pose hypothesis substantially overlaps with an image of an object to be identified from an image of a plurality of objects. In this manner, an object can be identified from among a plurality of objects based on the selected candidate six dimensional pose hypothesis.
US11420331B2	Motion retargeting control for human-robot interaction Controlling a robot may be performed by calculating a desired velocity based on an operator contact force and a robot contact force, calculating a transformation matrix based on an operator pose, a robot pose, a robot trajectory, the operator contact force, and the robot contact force, calculating a least square solution to Jf+{circumflex over (v)}f based on the desired velocity, calculating a scaling factor based on a current joint position of a joint of the robot, calculating a first trajectory based on the least square solution, the scaling factor, and the transformation matrix, calculating the robot trajectory, calculating a joint command based on the robot trajectory and the robot pose, and implementing the joint command.
US11420325B2	Method, apparatus and system for controlling a robot, and storage medium The present disclosure relates to a method, an apparatus and a system for controlling a robot, and a storage medium. The method uses a neural network connected to an external memory to conduct the controlling of the robot, and comprises: inputting input data into the learned neural network to obtain output data, wherein said input data comprises an image about an object, said output data comprises control data about said robot; and establishing an association between part or all of the information generated by said neural network during the calculation and said input data and/or said output data, wherein said part or all of the information represents a feature of said object related to said control data. Thus, the user can grasp the calculation process of the neural network.
US11420323B2	Method and control system for controlling movement sequences of a robot A method for controlling movement sequences of a robot, the method including predicting values of at least one parameter related to the execution of alternative movement sequences by the robot, where each movement sequence includes at least one movement segment associated with a handling location; selecting a movement sequence based on the predicted values of the at least one parameter; and executing the selected movement sequence by the robot. A control system for controlling movement sequences of a robot is also provided.
US11420321B2	Specifying data generating apparatus, specifying data generating method, and computer-readable medium having recorded thereon specifying data generating program A specifying data generating apparatus configured to generate specifying data for causing a robot to reproduce a motion of a target object including a generating unit configured to generate, based on manual data indicative of a motion of a target object manually operated, specifying data for specifying, in association with a time, a position and a posture of an end effector of a robot configured to imitate the motion of the target object, and a correcting unit configured, when a period during which a motion of the end effector operated according to the specifying data generated by the generating unit deviates from a predetermined tolerance has occurred, to correct, through extension in a time direction, the specifying data of at least the period during which there is the deviation from the tolerance.
US11420319B2	Platform extension mechanism A platform extension mechanism includes at least a bumper, a rolling bearing, an adjuster, and an axle. The axle has a first end surface and a second end surface. The axle is elongated along a first axis. The axle includes interior wall portions that define a slot from the first end surface to the second end surface. The axle is structured to receive the bumper and the adjuster via the slot. The axle is structured to support the bumper and the adjuster in relation to a platform and a structural channel. The axle includes a mounting portion and a shaft portion. The mounting portion has a flange with a first side and a second side. The first side of the flange is mountable to a sidewall portion of the platform. The shaft portion protrudes outward from the second side of the flange. The shaft portion has a peripheral portion that is structured to support the rolling bearing at a designated location along the first axis and enable the rolling bearing to move along the structural channel. The shaft portion is structured to support the bumper and the rolling bearing in a coaxial arrangement. The adjuster is aligned with the bumper and configured to adjust a position of the bumper along the first axis of the axle.
US11420318B1	Sturdy convertible worktable The present invention discloses a convertible worktable convertible between a storage configuration and an assembled use configuration. The worktable comprises a tabletop has a top surface and a bottom surface, a top frame fixed to the bottom surface of the tabletop and a bottom frame being spaced apart and coaxial to the top frame. The bottom frame having a first side and a second side opposite to the first side. The worktable further comprises a plurality of legs fastened to the top frame and extends beyond and in contact with the bottom frame. A fastener assembly detachably fastens the plurality of legs to the top frame and the bottom frame and defines an assembled use configuration. The fastener assembly allows detachment of the plurality of legs from the top and bottom frame, fastens the plurality of legs and the bottom frame alongside the top frame, and defines a storage configuration.
US11420310B2	Power tool A power tool, such as a hammer driver-drill (1), includes: a motor (8); a motor housing (7A) that holds the motor (8); a grip housing (7B) connected to the motor housing (7A); a battery mount housing or enlarged-part housing (7C) connected to the grip housing (7B); and a dial (24) that is provided in the enlarged-part housing (7C) such that it is rotatable about a dial shaft (29). A threshold for stopping the motor (8) is settable by rotating the dial (24).
US11420300B2	Component fitting structure and automatic assembly system having disengagement prevention function A component fitting structure includes: a first component including an elastic column provided with an engaging piece; and a second component including a cutout capable of being engaged by the engaging piece, in which the engaging piece includes a first protrusion protruding laterally from the elastic column and a second protrusion protruding in a direction opposite to a protrusion direction of the first protrusion, and the cutout includes a first edge configured to oppose the first protrusion and a second edge configured to oppose a part of the second protrusion and open a remainder of the second protrusion, after the first component and the second component are assembled.
US11420288B2	Laser machining systems and methods A laser machining method includes directing, from an F-theta lens having a long focal length of greater than about 250 millimeters, a laser beam at a non-perpendicular beam tilt angle from an optical axis of the lens having a top-hat profile and a narrow beam divergence angle of between about 1 degree and about 3 degrees towards a workpiece on a stage movable in at least an X-direction and a Y-direction, engaging the directed laser beam with the workpiece disposed in the usable field of view, moving the workpiece and the directed laser beam relative to each other, and removing portions of the workpiece with the directed laser beam to define a machined surface.
US11420286B2	Consumable designs for a plasma arc torch A liquid cooled electrode for a contact start plasma arc cutting torch is provided. The electrode includes an elongated body defining a longitudinal axis. The elongated body includes a proximal end shaped to matingly engage a torch body of the plasma arc cutting torch and a distal end located substantially opposite of the proximal end along the longitudinal axis. The electrode also includes one or more contact surfaces disposed on an external surface of the distal end of the electrode body between the proximal and distal ends. The one or more contact surfaces are shaped to physically contact a nozzle disposed within the plasma arc cutting torch during a portion of a pilot arc initiation process. The physical contact is configured to support transmission of a pilot arc current between the electrode and the nozzle with a density of at least about 3000 amps per square inch.
US11420285B2	Systems and methods for automated cleaning of wire electrodes after welding Systems and methods for cleaning a wire electrode after a welding process has ended are described. During a welding process, a wire electrode may be fed forward from a wire feeder through a welding torch to create a molten weld pool. While, conventionally, feeding of the wire electrode stops when the welding process ends, the present disclosure contemplates instead continuing to feed the wire electrode forward after the welding process ends. More particularly, the present disclosure contemplates feeding the wire electrode into the weld pool so that the wire electrode can be “cleaned” in the molten weld pool created by the welding process. The “cleaned” wire electrode end can be more easily used to establish an electrical arc at the beginning of the next welding process.
US11420279B2	Method of selectively bonding braze powders to a surface A method for selectively adhering braze powders to a surface comprises applying a binder material to a surface, depositing a braze powder on the binder material, and then directing a laser beam onto the braze powder while the laser beam moves along a predetermined path relative to the surface. The laser beam selectively heats the braze powder and the binder material along the predetermined path such that the binder material is removed and the braze powder is sintered and bonded to the surface. Thus, a braze deposit is formed at one or more predetermined locations on the surface. After forming the braze deposit, excess braze powder and binder material, that is, the braze powder and binder material not selectively heated by the laser, are removed from the surface.
US11420278B2	System and method employing active thermal buffer element for improved joule heating A system and method for more consistent joule heating of a material blank to a desired temperature. An electrical terminal delivers a current to an end portion of the blank. The terminal has a heat sink effect which would otherwise prevent the end portion from reaching the desired temperature. An active thermal buffer element is interposed between the terminal and the end portion. The buffer element includes a first surface which abuts the end portion and a second surface which abuts the terminal. The buffer element is joule heated with the blank, and a temperature gradient is created across the buffer element such that the first surface is at the desired temperature and the second surface is at a lower temperature due to the heat sink effect of the terminal. The buffer element thereby compensates for the heat sink effect and allows the end portion to reach the desired temperature.
US11420277B2	Wire electrical discharge machine and control method of wire electrical discharge machine A wire electrical discharge machine for machining a workpiece by generating electric discharge at a discharge gap between the workpiece and a wire electrode includes: a machining current setting unit for setting the magnitude of a normal machining current depending on the discharge gap state at application of a discharge induction voltage at the previous time or previous times; and a machining current control unit configured to control a main discharge circuit so as to supply the normal machining current to the discharge gap when the present discharge gap state is the normal state, control the main discharge circuit so as to supply a short-circuit machining current smaller than a predetermined current to the gap when the discharge gap state is the short-circuited state, and control the main discharge circuit so as not to supply any machining current to the gap when the discharge gap state is the open state.
US11420271B2	Adapter sleeve and cutting device An adapter sleeve is described for inserting into an expansion chuck of a cutting device with a substantially cylindrical body that defines a longitudinal axis (L) of the adapter sleeve and a seat area for a cutting tool. The body comprises an axial front end and an axial rear end opposite the front end by means of which the adapter sleeve can be inserted into the expansion chuck of the cutting device. An outlet element is provided at the axial front end through which a coolant can be discharged toward the cutting tool. At least one cooling line extends along the body up to the outlet element and comprises a body line section and an outlet element section. At least one channel-like outlet nozzle is formed in the outlet element and is in fluidic connection with the at least one cooling line. The flow cross-section of the cooling line decreases or remains the same toward the axial front end. In addition, a cutting device is described.
US11420269B2	Clamping assembly, a toolholder assembly comprising a clamping assembly and a toolholder, and a method of changing a toolholder in a toolholder assembly A clamping assembly includes a base member having an internal bore, a lock rod within the internal bore of the base member and moveable in a forward direction and rearward direction between an unlocked position and a locked position, a crank wheel having an axis of rotation, and a linkage coupled to the lock rod and coupled to the crank wheel at a position radially offset from the axis of rotation of the crank wheel.
US11420267B2	Cutting insert, cutting tool, and method for manufacturing machined product A cutting insert may include a first surface, a second surface, a third surface, and a land surface. The first surface may include a first corner, a first side, and a second side. The land surface may be inclined relative to the first surface and the third surface. The land surface may include a first land surface connecting to the first corner. An imaginary flat surface orthogonal to a central axis connecting a center of the first surface and a center of the second surface may be a reference plane, a first inclination angle of a part of the first land surface which connects to a midportion of the first corner may be larger than a second inclination angle of a part of the first land surface which connects to an end portion at a side of the first side of the first corner.
US11420265B2	Apparatus and method for continuous additive manufacturing An apparatus for continuous powder-based additive manufacturing of a large annular object or multiple smaller objects simultaneously is described. The build unit(s) of the apparatus includes a powder delivery mechanism, a powder recoating mechanism and an irradiation beam directing mechanism. The build unit(s) is attached to a rotating mechanism such that the build unit(s) rotates around and above the annular powder bed during production. The rotating mechanism is supported onto a central tower, and both the rotating mechanism and the tower are concentric with the non-rotating annular powder bed. An additive manufacturing method using the apparatus involves repetitive and continuous cycles of at least simultaneously rotating the build unit(s) to deposit powder onto the powder bed and irradiating the powder to form a fused additive layer. The continuous additive manufacturing process may be further aided with a helical configuration of the powder bed build surface.
US11420264B2	Method and a system for producing a three-dimensional object The present invention relates to a method for producing a 3D object and to a system adapted to implement the method, wherein the method comprises: —providing a powder material (G); —providing a radiation absorbent material, in the form of optically resonant particles (P), on a region to be sintered of the powder material; and—sintering the region to be sintered of the powder material (G), by exposing to light the optically resonant particles (P) to radiation. The method comprises providing the optically resonant particles (P) according to a distribution and proportion, with respect to the powder material (G) included in the region to be sintered, selected: —to disperse the optically resonant particles (P) within the powder material (G) included in said region, and—to avoid substantial agglomeration and substantial self-sintering of the optically resonant particles (P).
US11420263B2	Additive manufacturing cover gas shield A gas shield for an additive manufacturing system includes a bracket and a flexible curtain mounted to the bracket. A method of additively manufacturing includes removably mounting a gas shield to at least partially segregate a powder dispenser and a chamber.
US11420258B2	Method for manufacture of transition metal oxide fine particles The present invention provides a method for the manufacture of transition metal oxide fine particles, the method comprising the steps of: heating a strong-alkaline aqueous solution while stirring same; adding to and dissolving in the heated strong-alkaline aqueous solution a transition metal oxide; adding a strong-acid aqueous solution to the strong alkaline aqueous solution in which the transition metal oxide is dissolved, while stirring same, thereby re-dissolving a solid generated at the interface between the strong-alkaline aqueous solution and the strong-acid aqueous solution; adjusting the pH of the mixed aqueous solution resulting from mixing the strong-alkaline aqueous solution and the strong acid aqueous solution, through adjustment of the adding rate and amount of the strong-acid aqueous solution, to precipitate transition metal oxide fine particles; and separating the transition metal oxide fine particles from the mixed aqueous solution and sequentially washing, drying, and thermally treating the separated transition metal oxide fine particles.
US11420256B2	Silver powder and method for producing same A silver powder which has a small content of carbon and which is difficult to be agglutinated, and a method for producing the same. While a molten metal, which is prepared by melting silver to which 40 ppm or more of copper is added, is allowed to drop, a high-pressure water is sprayed onto the molten metal to rapidly cool and solidify the molten metal to produce a silver powder which contains 40 ppm or more of copper, 0.1% by weight or less of carbon and 0.1% by weight or less of oxygen and wherein the particle diameter (D50 diameter) corresponding to 50% of accumulation in volume-based cumulative distribution of the silver powder, which is measured by means of a laser diffraction particle size analyzer, is in the range of from 1 μm to 15 μm, the average particle diameter (SEM diameter) of single particles being in the range of from 1 μm to 8 μm when it is measured by means of a field emission scanning electron microscope (SEM), the ratio (SEM diameter/D50 diameter) of the SEM diameter to the D50 diameter being in the range of from 0.3 to 1.0.
US11420255B2	Film-shaped firing material and film-shaped firing material with a support sheet A film-shaped firing material 1 is provided, including sinterable metal particles 10 and a binder component 20, in which a content of the sinterable metal particles 10 is in a range of 15% to 98% by mass, a content of the binder component 20 is in a range of 2% to 50% by mass, a shrinkage factor in a planar direction of the film-shaped firing material after being pressurized and fired under conditions of a temperature of 350° C. and a pressure of 10 MPa for 3 minutes is 10% or less with respect to the shrinkage factor before the firing, and a volume shrinkage factor thereof is in a range of 15% to 90% with respect to the volume shrinkage factor before the firing, and a contact ratio of the film-shaped firing material with an adherend after being pressurized and fired under conditions of a temperature of 350° C. and a pressure of 10 MPa for 3 minutes in a state in which the film-shaped firing material is in contact with the adherend is 90% or greater with respect to a contact area of the adherend.
US11420253B2	Aluminum casting design with alloy set cores for improved intermetallic bond strength An engine block formed according to a method that includes forming an insert, coating the insert with a bond material, placing the insert within a casting mold or die, purging the casting mold or die with an inert gas, filling the casting mold or die with molten metal to encapsulate the insert, diffusion bonding the molten metal to the insert to form a diffusion bonded insert, placing the diffusion bonded insert within a cavity of a secondary casting mold or die, filling the secondary casting mold or die with molten metal to form an engine block composite casting assembly, and casting and heat treating the engine block composite casting assembly is provided. The insert can be free of serrations for mechanical coupling between the insert and the engine block.
US11420249B2	Aluminum wheels and methods of manufacture Aluminum wheels include a rim and a disc having a mounting portion. The mounting portion includes an inner mounting face and an outer mounting face. The mounting portion also includes a coarse grain region and a fine grain region. The coarse grain region can be adjacent, and at least partially form, one of the inner mounting face or the outer mounting face. The coarse grain region includes aluminum alloy grains of a first average grain length that is greater than 1 mm. The fine grain region extends between the coarse grain region and the other of the inner mounting face or the outer mounting face. The fine grain region includes aluminum alloy grains of a second average grain length that is less than 0.5 mm.
US11420246B2	Method for improving fatigue strength of a workpiece and the workpiece thereof The present disclosure discloses a method for improving fatigue strength of a workpiece (100). The method comprises positioning the workpiece (100) in a punch and die assembly (102). Operating the punch and die assembly (102) one or more times to imprint surface features (2) on a portion of a surface of the workpiece (100), wherein the surface features (2) induces compressive residual stresses at a sub-surface level of the workpiece (100), and improves the fatigue strength of the workpiece (100).
US11420244B2	Rolling mill with cooling or lubricating device Disclosed is a rolling mill including: a stand; two working rolls, two support rolls, and two intermediate rolls; lateral support rolls, able to support the working rolls laterally, each lateral support roll being borne by a support arm, mounted with the ability to pivot; load spreading beams and a mechanism for applying a preload on each support arm, including at least one preload actuating cylinder; one or more spray nozzles for a lubricating/cooling fluid, and wherein at least one of the nozzles, is carried on one of the support arms and in which the fluid supply circuit for the at least one nozzle comprises a device for connection/disconnection with the support arm with actuator. The actuator is an actuator distinct from the actuating cylinder of the mechanism for applying a preload.
US11420235B2	Powered scrubbing wand assembly A powered scrubbing wand assembly for scrubbing a surface includes a handle that can be gripped during cleaning activities. A cleaning head is coupled to the handle and a drive unit is integrated into the handle. The drive unit rotates in a first direction when the drive unit is turned on. A spray unit is integrated into the handle for spraying a fluid soap when the spray unit is turned on. A plurality of scrubbers is each removably attachable to the cleaning head. The drive unit rotates the scrubber on the cleaning head when the drive unit is turned on thereby facilitating the scrubber to scrub a surface.
US11420228B2	Apparatus and method for removing bubbles in flexible substrate The present disclosure provides an apparatus for removing bubbles in a flexible substrate. The flexible substrate includes a baseplate and a polyimide layer coated on the baseplate. The apparatus includes a chamber including a top wall, a sidewall, and a bottom wall, wherein the top wall, the sidewall, and the bottom wall define an accommodation space; a heating plate disposed in the accommodation space; and a cooling conduit embedded in at least one of the top wall and the sidewall of the chamber.
US11420224B2	Apparatus and method for coating substrates with washcoats An apparatus and method of coating a substrate with a washcoat comprising: engaging the substrate (110) with a headset (6) of a substrate coating apparatus (100) so as to locate an upper surface of the substrate below a washcoat showerhead of the substrate coating apparatus; arranging a partition (200) between the washcoat showerhead and the upper surface of the substrate, the partition comprising a plurality of holes (202) and being located in the headset to maintain a first gap between a lower face (203) of the partition and the upper surface of the substrate; discharging a washcoat out of the washcoat showerhead onto an upper face (204) of the partition; and passing the washcoat through the holes (202) in the partition, onto the upper surface of the substrate and into the substrate, at least in part by applying a suction force to a lower surface of the substrate.
US11420223B2	High pressure spray head A device for spraying substrates comprises a longitudinal extending fluid dispensing head coupled to a supply of fluid and including a perpendicularly extending flange, a spacer having first and second ends, the first end of the spacer coupled to the extending flange of the dispensing head, a nozzle adapted to eject fluid coupled to the second end of the spacer, and a locking nut enclosing the spacer and securely the dispensing head, spacer and nozzle.
US11420222B2	Vehicle painting method and painting system A method of painting a vehicle according to an embodiment including a first member and a second member which includes a painting surface and which is made of a material different from that of the first member. The method includes acquiring an environmental condition and a painting condition when the first member has been painted, and determining an environmental condition and a painting condition for the second member, which are determined in advance so that a color of the second member and a color of the first member will have a sameness in view of the acquired environmental condition and painting condition for the first member, as the environmental condition and the painting condition at the time of painting the second member which may be used together with the first member.
US11420219B2	Printing apparatus for printed electronics A printing apparatus for printed electronics according to the present invention may include: ejection head units which each have at least one nozzle for ejecting ink droplets to perform drop-on-demand or continuous printing; a jetting observation unit which is provided at one side of the nozzle and configured to observe the ink droplet ejected from the nozzle; a lighting unit which is provided at the other side of the nozzle and configured to provide light to the jetting observation unit; an alignment observation unit which is configured to observe an aligned state between the nozzle and a substrate; and a fluid supply unit which is configured to supply the ink to the nozzle, in which the ejection head units include a single-nozzle head unit, and a multi-nozzle head unit provided separately from the single-nozzle head unit.
US11420217B2	Showerhead for ALD precursor delivery Embodiments of showerheads for use in a process chamber are provided herein. In some embodiments, a showerhead includes a first spiral channel extending from a central region to a peripheral region of the showerhead; a second spiral channel extending from a central region to a peripheral region of the showerhead, wherein the second spiral channel is interleaved with the first spiral channel and fluidly independent from the first spiral channel; a plurality of first channels extending from the first spiral channel to a plurality of first gas distribution holes on a lower surface of the showerhead, wherein each first channel is a singular channel extending at an angle; and a plurality of second channels extending from the second spiral channel to a plurality of second gas distribution holes on the lower surface of the showerhead, wherein each second channel is a singular channel extending at an angle.
US11420213B2	Machine for magnetic separation A machine is described for magnetic separation of material, wherein the machine includes a supporting structure and at least one magnetic rotating drum supported by the supporting structure, wherein the machine further includes a vehicle for moving and transporting the supporting structure. The magnetic drum includes an outer rotating shell and a magnetic portion including at least one magnet positioned and housed within the outer shell, wherein the outer shell is rotatable around a central axis by a drive mechanism and the at least one magnet is positioned in a fixed location within the outer shell.
US11420212B2	Methods and devices for controlling the dry granulation process The invention relates to a continuous dry granulation method and non-invasive monitoring and control of the dry granulation method. The invention further describes a dry granulation system and uses thereof. In particular, the non-invasive monitoring methods employ a sound, force, strain, vibration and/or acceleration sensor in order to determine the mechanical strength of a compacted material during a dry granulation process. Further, the compaction parameters of the compacting unit of the granulation process may be controlled to maintain a target mechanical strength of the compacted material.
US11420209B2	Variable spacing rack A variable spacing PCR amp tube rack can include a plurality of rotors and a plurality of carriages engaged with the rotors so that rotation of the rotors causes translation of the carriages with respect to one another. The rack can include a blade assembly that allows an operator to separate sets of coupled PCR amp tubes from one another. The rack can be designed to accommodate 0.1 ml PCR amp tubes and adjust their spacing from 4.5 mm to 9.0 mm.
US11420205B2	Instrument and method for energizing molecules in charged droplets An instrument for energizing molecules contained in a sample solution may include a droplet generator configured to generate droplets of the sample solution. The droplet generator illustratively has an elongated nozzle defining an orifice at one end thereof from which the droplets exit the droplet generator, and the orifice illustratively defines a first longitudinal axis centrally therethrough. A molecule energizing source is configured to produce a molecule energizing field, and is positioned relative to the nozzle orifice such that the molecule energizing field extends into at least some of the generated droplets along a direction non-parallel with the first longitudinal axis. The molecule energizing field illustratively carries energy which heats at least one of the generated droplets sufficiently to induce structural changes in at least one molecule contained in the at least one of the generated droplets.
US11420203B2	Point-of-care diagnostic assay cartridge The invention provides a microfluidic system comprising a cartridge coupled to a motor and adapted to move a fluid sample to a plurality of locations on the cartridge. The cartridge comprises a chevron shaped or substantially V shaped reaction chamber having at least three zones, a first zone positioned near the apex of the V shaped reaction chamber to define a detection zone, a second zone positioned near a first end of the V shaped reaction chamber and a third zone positioned near a second end of the V shaped reaction chamber. The motor and a control module is configured to provide a combination of centrifugal force and gravitational force to move said fluid sample between at least three zones.
US11420197B2	Apparatus and method for mixing fluid or media by vibrating a pipette using nonconcentric masses Methods and apparatuses for mixing a fluid/media for an assay are disclosed herein. In an embodiment, a mixing device for an immunochemistry system includes a pipette configured to aspirate fluid and/or paramagnetic particles from or dispense fluid and/or paramagnetic particles into a cuvette, at least one nonconcentric mass configured cause the pipette to move in a mixing motion, and a control unit configured to activate the at least one nonconcentric mass while the pipette is located within the cuvette so as to mix the fluid and/or paramagnetic particles within the cuvette.
US11420191B2	Shaped dehydrogenation catalysts and process for converting paraffins to corresponding olefins, using same Disclosed herein are a dehydrogenation catalyst having single-atom cobalt loaded on a silica-based, shaped support, a preparation method therefor, and a method for preparing an olefin by dehydrogenating a corresponding paraffin, particularly light paraffin in the presence of the dehydrogenation catalyst.
US11420188B2	Smart paper transformer for enhanced catalytic efficiency and reusability of nanocatalysts A method of synthesizing a smart paper transformer is provided. The method comprises combining paper with HAuCl4 and stirring together in an aqueous solution to form a pulp. The pulp is treated with NaBH4 aqueous solution. The treated pulp is then washed and centrifuged with water a number of times to form a gold nanosponge (AuNS) catalyst pulp.
US11420183B2	Method of preparing carbon-based sulfur-loading iron-containing adsorbent for mercury removal This invention introduces a method of preparing a carbon-based sulfur-loading iron-containing adsorbent for mercury removal, which can solve the problems in the prior art that sulfur-rich heavy organic materials have low-value utilization and the elemental mercury in atmosphere is hard to be efficiently and economically removed by the existing mercury removal agents. A carbon-based sulfur-loading iron-containing adsorbent for mercury removal is prepared in this invention. The adsorbent with a porous structure is prepared in situ by performing steps such as chemical activation of sulfur-rich heavy organic materials that are rich in iron. The adsorbent prepared herein has good mercury removal performance in simulated coal-fired flue gas. This invention not only improves the utilization value of sulfur-rich heavy organic materials, but also prevents SOX pollution caused by the combustion of sulfur-rich heavy organic materials and controls mercury pollution in the coal-fired flue gas.
US11420181B2	Methods for suppression of ammonia formation from staphylococcus-xylosus and staphylococcus-cohnii A method for suppressing the formation of ammonia comprising providing a carrier material to a container having a headspace; providing a bacteria, an acidifier and an odor inhibitor to the carrier material, the bacteria comprising Staphylococcus-xylosus or Staphylococcus-cohnii bacteria, and the odor inhibitor comprising a salt of an aminopolycarboxylic acid compound; and applying animal waste to the carrier material; wherein there is a 5 to 98 percent improvement of ammonia content in the headspace as compared to an untreated control comprising a container containing the carrier material and the bacteria and not contain the odor inhibitor.
US11420180B2	Reactor arrangement and method for pre-hydrolysis of biomass material A reactor arrangement for pre-hydrolysis of biomass material. The reactor arrangement comprises a reactor vessel arranged substantially horizontally, wherein the vessel comprises an inlet for receiving the biomass material arranged at an upper portion of the vessel. The inlet may be arranged at a first longitudinal end of the vessel. The vessel may furthermore comprise an outlet at a second longitudinal end of the vessel. The reactor arrangement further comprises a set of steam injection orifices arranged to inject or supply steam into the reactor vessel. The set of steam injection orifices comprises at least two orifices arranged below the inlet at a distance from each other. The at least two orifices may be arranged at a distance from each other in the lateral direction of the reactor vessel. Furthermore, a method for pre-hydrolysis treatment of biomass in a substantially horizontal reactor vessel is provided.
US11420177B2	Flexible chemical production method Disclosed herein is a method for converting an epoxide to a first C3 product, a second C3 product, and/or a first C4 product within an integrated system. The method includes converting the epoxide to a beta lactone to produce an outlet stream comprising beta lactone. The method includes converting the beta lactone of the outlet stream to a first C3 product in the first C3 reactor to produce an outlet stream comprising the first C3 product; converting the beta lactone to a second C3 product in the second C3 reactor to produce an outlet stream comprising the second C3 product, and/or converting the beta lactone to a first C4 product in the first C4 reactor to produce an outlet stream comprising the first C4 product.
US11420173B2	Reaction analysis device, reaction analysis system, and reaction analysis method A reaction analysis device specifies a reaction state of a reaction fluid flowing through a flow reactor. The reaction analysis device includes a processor configured to specify the reaction state of the reaction fluid based on a reaction parameter indicating the reaction state of the reaction fluid which is obtained from a temperature distribution of the reaction fluid immediately after a reaction starts in a flow direction of the reaction fluid.
US11420172B2	Jacketed vessel A jacketed vessel for temperature control of contents within the vessel is provided. The vessel has a shell and an external jacket through which heating or cooling fluid is circulated. The jacket is formed by a length of conduit arranged in a spiral orientation around the vessel shell. The conduit has a center portion having a concave inner surface and has opposing side portions having convex inner surfaces. Edge sections of each side portion are welded to the exterior surface of the shell to form the jacket. Edge sections of adjacent arcs of conduit may be simultaneously welded to the shell in a single weld pass. The shape of the conduit provides improved heat transfer and pressure drop characteristics, as well as improvements in the vessel manufacturing process.
US11420168B2	Mixing machine and related methods A mixing machine (1) for the mixing of a homogeneous mixture with one or more components to obtain a viscous mixture, comprising a mixing chamber (2) which is divided in a push (A), a mixing (B) and a discharge zone (C), and wherein the mixing chamber (2) comprises the following parts: multiple walls, consisting of one or more top plates (22) with multiple inflow channels (10, 11, 12), one or more bottom plates (24) and multiple side walls (6); an outlet mouth (18); an outlet valve (13); several rotors (5); in and out sliding push and/or mixing blades (3, 4); and a self-cleaning system (16, 17); characterised in that the rotors (5) are integrated in the side walls (6) of the mixing chamber (2); the rotors are equipped with transit channels (30) for the in and out sliding push or mixing blades (3, 4); and the self-cleaning system comprises a cleaning plate (16) and a driving mechanism (17) wherein the cleaning plate (16) can move longitudinally through the mixing chamber (2).
US11420166B2	Agitator device and method An agitator device is provided having at least one carrier unit, which has at least one connection element for a connection to a drive shaft and at least one beam element for the fastening of at least one agitator blade. The beam element and the connection element may be connected to one another in a one-part implementation.
US11420164B2	Method of deionizing saline water with a diffusion barrier A method of deionizing saline water by contacting the saline water with a diffusion barrier to remove at least a portion of divalent ions to form deionized water, in order to desalinate the deionized water without scale formation, and a method of fabricating the diffusion barrier. Various embodiments of the diffusion barrier, the method of fabricating thereof, and the method of deionizing the saline water are provided.
US11420163B2	Nanofiltration composite membrane, and preparation method and application thereof The present invention discloses a nanofiltration composite membrane, a preparation method and application thereof. The preparation method comprises: A) preparing 2D nano-material dispersion; B) first preparing a solution of a polymer material with a certain concentration, continuously adding a poor solvent under stirring conditions to subject the polymer material to chemical reaction to obtain a dispersion containing negatively charged polymer gel particles; C) subjecting the nano-material dispersion in step A) and the dispersion prepared in step B) to blending, membrane preparation and drying, and then placing the membrane into an alkaline solution with a certain concentration and pure water for soaking to obtain a nanofiltration composite membrane. The nanofiltration composite membrane can efficiently remove heavy metal complex ions through the synergistic effect of pore size screening and charge repulsion. Moreover, the rejection rate and flux of the nanofiltration composite membrane have not changed obviously after use for a long time.
US11420162B2	Method for preparing porous membrane of fluorine-based resin The present invention provides a method for preparing a porous membrane of a fluorine-based resin having an improved shrinkage while maintaining excellent filtration efficiency and air permeability.
US11420156B2	Electrochemical dehumidification device based on screen-type amphoteric ion exchange membrane electrode Disclosed is an electrochemical dehumidification device based on a screen-type amphoteric ion exchange membrane electrode, comprising a core dehumidification unit which comprises, sequentially from one side to the other side, an anode air pathway, a screen-type anode electrode, an amphoteric ion exchange membrane, a screen-type cathode electrode and a cathode air pathway. The core dehumidification unit performs active dehumidification when a voltage is applied, and performs passive dehumidification when no voltage is applied. A number of the core dehumidification unit is equal to or more than one, the core dehumidification units are capable of being connected in parallel, in serial or in an overlapping mode; meanwhile, the units may also be used in combination with other dehumidification devices. The device achieves active/passive dehumidification, and is ultra-compact and flexible.
US11420152B2	Bandpass filter for separation of a specifically selected gas from a group of gases or an atmosphere A method of separation of predetermined gas from the mixture of gases or an atmosphere, wherein said method of separation of predetermined gas from a mixture of gases or an atmosphere comprises passing a mixture of gases or an atmosphere through the reinforced mass selective fluid bandpass filter (8). The reinforced mass selective fluid bandpass filter comprises the mass selective fluid bandpass filter element (9) permanently affixed to the sintered metal load bearing structure (14). The mass selective fluid bandpass filter element consists of quartz glass, of either natural or manmade origin. This method provides removing predetermined gas from the group consisting of: 1H2, 1H2H, 2H2, 1H3H, 2H3H, 3H2, 1H2O, 1H2HO, 2H2O, 1H3HO, 2H3HO, 3H2O, O2, O3, 12CO2, 13CO2, 14CO2, 4 CO, N2, NO, NO2, NOx, SiO2, FeO, Fe2O3, SiF4, HF, NH3, SO2, SO3, H2SO4, H2S, 35Cl2, 37Cl2, F2, Al2O3, CaO, MnO, P2O5, phenols, volatile organic compounds, and peroxyacyl nitrates.
US11420151B2	Air separation modules, nitrogen generation systems, and methods of making air separation modules An air separation module includes a canister, a separator, and a first end cap. The canister has an interior, a first open end in fluid communication with the interior of the canister, and a second end opposite the first open end of the canister. The separator is arranged within the interior of the canister, the separator fluidly coupling the second open end of the canister with the first open end of the canister. The first end cap has a one-piece first end cap body, is fixed to the first open end of the canister and has a first flange portion and a first aircraft-mounting portion. The canister supported by the first aircraft-mounting portion through the first flange portion of the one-piece first end cap body without an intermediate support structure. Nitrogen generation systems and methods of making nitrogen generation systems are also described.
US11420149B2	Efficient method and device for adsorption/desorption of carbon dioxide from gas streams A method for separating carbon dioxide and water from a gas mixture by cyclic adsorption/desorption, using a unit containing an adsorber structure, comprising the following repeating steps: (a) contacting said mixture with sorbent material; (b) at least one of evacuating said unit and heating said sorbent material and extracting the gaseous carbon dioxide and water vapour and separating gaseous carbon dioxide from water vapour; (c) cooling the adsorber structure and re-pressurisation; wherein (i) in step (c) the heat released is stored in a first heat storage device; (ii) during step (b) the sensible and latent heat of gaseous carbon dioxide and water vapour as product gases is stored in second heat storage device; and (iii) during step (b) the heat required for heating said sorbent material is supplied from heat recovered in at least one of step actions (i) and (ii) of previous sequence(s).
US11420147B2	Filter cartridges; air cleaner assemblies; housings; features; components; and, methods According to the present disclosure, air cleaner assemblies, housings, serviceable filter cartridges and features, components, and methods, relating thereto are disclosed. In general, the features relate to systems that are configured to aid in inhibiting an improper cartridge from being installed in an air cleaner housing, during servicing. A variety of features are characterized, and in many examples, the cartridge includes a seal arrangement having radially directed seal surface with at least a first non-wavy or non-projection/recess section and a second wavy or projection/recess section. Examples are shown and described in detail.
US11420145B2	Tubular filter and system for filtration of polluted ambient air A tubular filter for dynamic cleaning of an air flow containing suspended particles and a system for filtration using this filter includes a flow channel (1), carried out curved and a unit (6, 8) for generating an air flow in the flow channel (1). The tubular filter is arranged in a low pressure chamber (2) and is configured to generate Dean vortices in its curved portion. On outer and inner parts of the curved portion of the flow channel (1) are provided outer (10) and inner (20) openings, respectively, for discharging suspended particles from the flow channel (1) in the low pressure chamber (2). The system for filtration includes a filtration unit (22) with at least one tubular filter (21), a control unit (17) for controlled regulation of the unit (6) for generating a flow in the flow channel (1) and an electric power supply unit (18).
US11420143B2	Filter media with irregular structure and/or reversibly stretchable layers Articles and methods relating to filter media are generally provided. In some embodiments, a filter media has an irregular surface structure. For instance, the filter media may comprise a plurality of peaks that are irregular in one or more ways. A ratio of a peak height standard deviation to an average peak height may be greater than or equal to 0.05, and/or a ratio of a peak spacing standard deviation to an average peak spacing may be greater than or equal to 0.08. In some embodiments, a filter media comprises a non-woven fiber web having a layer thickness of greater than 0.3 mm and/or a stiffness of less than or equal to 100 mg.
US11420141B2	Fuel filter cartridge with keyed profile A filtration system comprises a filter head assembly comprising an outlet slot, valve element, and latch element. The valve element is in fluid communication with the outlet slot and includes an open position and a closed position. In the open position fluid flow travels through the outlet slot. In the closed position fluid flow is prevented through the outlet slot. The latch element is configured to lock the valve element in the closed position. The filtration further comprises a filter cartridge structured to engage the filter head assembly. The filter cartridge comprises a first and second filter end. The filter cartridge comprises filter media and a keyed element disposed on the first filter end. The keyed element is structured for engagement of the latch element, wherein the engagement unlocks the valve element causing the valve element to be in the open position.
US11420139B2	Filter press and filter press of spiral vibration cake unloading by pulling apart filter plates twice A filter press includes a frame, a power component and a plurality of filter plates driven by the power component to move to and fro along the frame to be at a pressure filtration position and an unloading position; a vibration cake unloading device includes a driving component and a vibration shaft longitudinally arranged; and protrusions are provided on an outer circumferential wall of the vibration shaft, when the filter plates are located at the unloading position, in the process that the driving component drives the vibration shaft to rotate around its own axis, the protrusions on the vibration shaft collide with the filter plate to assist in unloading. The vibration shaft has a simple structure, which can greatly reduce the cost, and the vibration cake unloading device is flexible in use. A filter press of spiral vibration cake unloading by pulling apart the filter plate twice is further provided.
US11420138B2	Container for use when making a multi-layered blood product A container to be used for preparing a multi-layered blood product by centrifugation comprises a substantially cylindrical body (2) with a closed bottom (3) and a top (4) having a filling opening as well as a filter device (15), which is slidable inside the container (1). The filing opening is closed by means of a penetrable membrane (13), and the filter device (15) comprises a substantially planar mesh (16) and a supporting buoyancy body (18). In addition to this, there are means (35, 36, 39, 40, 42), for releasable fixation of the filter device (15) adjacent to the bottom (3) of the container (1).
US11420137B2	Effluent processing apparatus for a vehicle air brake charging system An effluent processing device includes an input port to receive an effluent mixture containing air, oil, and water. One or more baffles are positioned between the input port and at least one air outlet to deflect the effluent mixture to assist in separating the oil and the water from the air. A member positioned below the one or more baffles selectively allows only oil of the separated oil and water to pass from a first side of the member through openings in the member to a second side of the member. A sump is arranged to receive and retain the oil on the second side of the member as the oil passes from the first side to the second side. The effluent processing devices includes at least one air outlet through which air is exhausted to atmosphere.
US11420135B2	Multi-pass contact tray for a mass transfer column and method involving same A multi-pass contact tray for use in a mass transfer column has a mixture of fixed valves to movable valves, with the numbers of the respective valves being selected to balance the volumetric flow of vapor through deck segments when the vapor is ascending at volumetric flow rates insufficient to maintain the movable valves in an open position.
US11420133B2	Moldable material toy builder A toy set includes: a first mold portion including: a first base portion, andan indentation formation portion extending from the first base portion, the indentation formation portion including an edge. The first mold portion is configured to receive a moldable material, the indentation formation portion is configured to form an indentation in a first side of the moldable material, and the indentation allows the moldable material to fold without separating.
US11420131B2	Systems and methods for facilitating secret communication between players during game play Systems and methods for facilitating secret communication between players are described. One of the methods includes receiving image data of a first player to identify one or more gestures and receiving input data indicating a response of a second player to the one or more gestures. The method further includes training a model using the image data and the input data to generate an inference of communication between the first user and the second user. The method also includes generating additional inferences of communication between the first user and the second user. The method includes generating a recommendation to the second user based on the inference of communication and the additional inferences of communication.
US11420127B2	Device and method for recording game result by conducting game among plurality of users, and computer program A method of playing a game between a plurality of users and recording a game result thereof includes: registering the plurality of users including a first user and a second user in a blockchain network; performing, by the first user and the second user, a game according to execution of a first game application; obtaining, from the first game application, first game result information as a game result the game played between the first user and the second user; and updating game history information of the blockchain network based on the first game result information.
US11420120B2	Program, information processing apparatus, and control method for providing a strategic battle game A computer program product which may cause an information processing apparatus to execute steps of associating one group with each of a plurality of game media, arranging a plurality of game media on a field, starting a battle, arranging a first object associated with a plurality of parameters on the field according to a progress situation of the battle, executing a first change process of changing a parameter of the first object according to a control process of the game medium, stopping the executing of the first change process of the parameter if the parameter of the first object reaches the predetermined value, increasing points of the group corresponding to the parameter that has reached the predetermined value, and determining a result of the battle.
US11420118B2	Overlapping encode and transmit at the server A method for cloud gaming. The method including generating a video frame when executing a video game at a server. The method including scanning-in the video frame to an encoder at the server scanline-by-scanline. The method including encoding one or more encoder slices as one or more encoded slices at the encoder, wherein each encoded slice is delivered to a buffer at an encoder fill rate. The method including draining a first encoded slice from the buffer to stream the first encoded slice at a buffer drain rate over a network to a client, wherein the first encoded slice is streamed over the network before fully encoding the one or more slices of the video frame.
US11420117B2	Methods implementing doorbell register/file identification table with high-speed data communication fabric for cloud gaming data storage and retrieval A method provides for requesting data in a cloud gaming system that includes a cloud storage system and a cloud compute system, each of which has a respective peripheral component interconnect express (PCIe) interface and a respective computer memory. The cloud gaming system includes a PCIe switch connected to both the PCIe interface of the cloud storage system and the PCIe interface of the cloud compute system. The PCIe switch exposes a doorbell register that is monitored by the cloud storage system. The cloud compute system writes to the doorbell register, which causes an interrupt to fire on the cloud storage system. The cloud storage system handles the interrupt, which directs the cloud storage system to read a message from a specified computer memory location. The message directs the cloud storage system to read requested data from a storage device accessible by the cloud storage system.
US11420116B2	Augmented reality mobile edge computing Processing of actions within a shared augmented reality experience is split between an edge node of a communications network (e.g., a cell tower) and a server. As a result, computation of the current state may be sharded naturally based on real-world location, with state updates generally provided by the edge node and the server providing conflict resolution based on a master state (e.g., where actions connected to different edge nodes potentially interfere with each other). In this way, latency may be reduced as game actions are communicated between clients connected to the same edge node using a peer-to-peer (P2P) protocol without routing the actions via the game server.
US11420114B2	Systems and methods for enabling time-shifted coaching for cloud gaming systems Systems and methods are provided for enabling users playing online games to create coaching videos of gameplay, and post such coaching videos to a cloud gaming system. In one example, coaching videos include a video clip of the gameplay and a video of the user, guiding and/or explaining how the game was played. A user playing the same game may desire coaching, and the cloud gaming system can identify previously posted coaching videos that correspond to the point in time or action in which the user requesting coaching is currently playing. The cloud system can access a database of coaching options, which are then presented to a user. The coaching options may be videos of gameplay and videos of the user providing coaching. The user can then view the coaching videos, rate them if desired, and then resume with his or her gameplay.
US11420112B2	System and method for operating match-up game The system for operating a match-up game includes a display unit having a plurality of player screen regions configured to display game screens a first input unit configured to receive an input from a first player a second input unit configured to receive an input from a second player a first air outlet configured to discharge air to the first player a second air outlet configured to discharge air to the second player; a control unit configured to control the display unit to count a game time and change the game screens displayed on the player screen regions for each counted game time, and when receiving an input to the first input unit from the first player, control the second air outlet so as to discharge air corresponding to the received input. The system for operating a match-up game may increase a player's sense of immersion.
US11420111B2	Large-screen VR integrated game machine A large-screen VR integrated game machine comprises an upper assembly moveably attached to a lower assembly. A VR head mounted display retracting device positioned within the interior of the upper display, comprises a power transmission system, an electrical control system and a pulley system. The VR integrated game machine moveable upper assembly provides a folding structure that allows easier maintenance and upgrades of the equipment under unattended operation. Because the game machine is foldable the height can be shortened to alleviate transportation difficulties and set up at an operation site.
US11420109B2	Method for tracking the physical activities of a user in real world to interact with a virtual environment The invention discloses a system and method for tracking physical activities of a user in real world engaging in a virtual world. Based on at least one of a sensor data received from the user by means of a communication channel while performing a real-world activity, The system further generates a virtual journey schedule in the virtual world based on a user preference or a system preference and maps the real-world activity to the virtual journey by analyzing the received sensor data. The virtual journey schedule is generated based on the pace of the user.
US11420107B2	Method and apparatus for detecting a dealing sequence, storage medium and electronic device The present disclosure provides a method and apparatus for detecting a dealing sequence, a storage medium, and an electronic device. The method includes: obtaining a video stream of a game desktop, and detecting a game card from multiple image frames included in the video stream; in response to detecting a newly added game card from at least one of the multiple image frames, determining whether the newly added game card is in a target state in which dealing ends; after it is determined that the newly added game card is in the target state in which dealing ends, determining game information corresponding to the newly added game card; and determining, based on the game information, whether a sequence of dealing the newly added game card conforms to a predetermined dealing sequence.
US11420106B2	Adjustable hockey runner assembly A multi-degree of freedom ice skate post that connects an ice skate blade to the sole of an ice-skating boot generally comprises a plurality of adjustable elements that include a pronate/supinate platform, a bi-directional module and a side/side module. In some configurations, the pronate/supinate platform is configured to move the ice skate blade in a pronate and supinate direction. In some configurations the pronate supinate platform is connected with the bi-directional module providing movement of the ice skate blade in the fore and aft position. In some configurations the side/side module is connected with the bi-directional module providing movement in a side by side direction. Additional configurations can include vertical adjustments as well.
US11420105B2	Oral device having wedges and method of manufacture An oral device may include a body. The body may have a main portion having an arch-shaped central portion, a first side portion extending from a first end of the central portion, and a second side portion extending from a second end of the central portion. The body may further include a first wedge portion provided on a bottom surface of the first side portion, and a second wedge portion provided on a bottom surface of the second side portion. Each of the first wedge portion and the second wedge portion may have a varying thickness.
US11420103B2	Systems and methods for playing enhanced disc golf A method for playing disc golf on a course having a plurality of targets includes the steps of (a) obtaining a random selection device configured to randomly select one of a plurality of different types of throws, and one of a plurality of different types of discs, (b) the player activates the random selection device to obtain a randomly selected throw, and a randomly selected disc, and (c) the player throws the randomly selected disc with the randomly selected throw at the target. The steps are repeated for each target until the course is completed. The random selection device can be a set of dice.
US11420100B2	Grooves of golf club heads and methods to manufacture grooves of golf club heads Putter type club head with vertical groove patterns are described herein. A putter type club head comprises a putter face having a plurality of first curved grooves and a plurality of second curved grooves. The first curved grooves and the second curved grooves extend in a general vertical direction, and intersect each other at a plurality of points across the putter face. The width and depth of the first curved grooves and the second curved grooves can vary across the putter face in a direction extending from a heel end to a toe end, and/or in a direction extending from a top rail to a sole. The vertical groove pattern provides consistent ball speed performance for any impact location on the putter face.
US11420099B2	Putter striking face configuration to progressively reduce dispersion A putter type golf club head having a frontal ball striking face that engages and grips a golf ball during the execution of a putting stroke to direct the golf ball in a straight line toward the intended target. The face includes a plurality of ball striking land areas and a plurality of adjacent and complimentary recessed channels that form an opening toward and on either side of the midpoint of the hitting area of the face. The ball contact areas are smaller than the adjacent recessed channels at the midpoint of the hitting area of the face. Gripping edges at the interface of the land areas and the recessed channels redirect the golf ball toward the intended target when the ball is miss hit away from the midpoint of the face.
US11420097B2	Golf club head Described herein is a golf club head that comprises a body and a strike plate. The body comprises a heel portion, a sole portion, a toe portion, and a top portion. The strike plate comprises an outer peripheral edge and at least a portion of a strike face. Furthermore, the strike plate is welded to the body via a peripheral weld between the outer peripheral edge of the strike plate and the body. The outer peripheral edge of the strike plate comprises at least one welded portion, welded to the body via the peripheral weld, and at least one non-welded portion, not welded to the body.
US11420095B2	Breath control device A breath control device comprising t least one longitudinal tube with a wall with at least a resilient part, wherein the tube is embodied with a proximal open end and a closed distal end, and that the wall of the tube is provided with one or more at least in part active user-controlled closable openings or slits so that the fidgeting device also embodies a breath exercise device.
US11420091B2	Closed-circuit sliding-belt gymnastic machine and manufacturing method thereof A gymnastic machine comprising a frame having a base, wherein said base comprises a first and a second longitudinal member, a closed-circuit sliding-belt associated with said base, arranged between said first and said second longitudinal member, on which a user can execute a gymnastic exercise, and a transmission assembly having an electric motor, configured to move said closed-circuit sliding-belt, wherein said gymnastic machine. The electric motor is arranged below said closed-circuit sliding-belt.
US11420087B2	Pilates reformer exercise machine A device for use with an exerciser device, such as a reformer, which permits adjustment of a resistance system, even when connected to a resistance source, by selectively relieving a resistance force imparted on the resistance adjustment system when changing a resistance and automatically reengaging the resistance force when exercising. A strain relief is coupled to a linkage between the resistance source and a resistance adjuster. When engaged, the strain relief selectively reduces the resistance force transmitted through the linkage to the resistance adjuster to permit movement of the resistance adjuster relative to a purchase. When disengaged the strain relief permits transmission of the resistance force through the linkage to the resistance adjuster.
US11420085B2	Ozone cleaning system An ozone cleaning system includes a decontamination chamber, a utility chamber coupled to the decontamination chamber, and a utility assembly disposed within the utility chamber. The utility assembly is configured to decontaminate at least one of contaminated gear and contaminated equipment positioned in the decontamination chamber by treating organic carcinogens. The utility assembly includes an ozone generator configured to provide ozone to the decontamination chamber, a humidifying unit configured to provide humidity to the decontamination chamber, and a vacuum blower configured to at least one of (i) generate a vacuum within the decontamination chamber and (ii) pull the ozone from the decontamination chamber following a decontamination process.
US11420084B2	Long-term fire retardant with corrosion inhibitors and methods for making and using same A forest fire retardant composition contains a retardant compound that includes a phosphate salt. The phosphate salt may include diammonium phosphate, diammonium orthophosphate, monoammonium phosphate, monoammonium orthophosphate, monosodium phosphate, disodium phosphate, disodium phosphate hydrate, sodium ammonium phosphate, sodium ammonium phosphate hydrate, sodium tripolyphosphate, trisodium phosphate, or dipotassium phosphate, and combinations thereof. The forest fire retardant composition may include an ammonium source. The composition may be in the form of a dry concentrate, a liquid concentrate, or a final diluted product. The final diluted product is effective in suppressing, retarding, and controlling forest fires while exhibiting corrosion resistance and low toxicity.
US11420083B2	Zwitterionic and glucoside surfactant formulations for fire-fighting foam applications A composition having water and first and second surfactants having the formulas below. The values m and y are non-negative integers, and n and x are positive integers. R is a zwitterionic group. R′ is a siloxane group. A foam of the composition may be used to extinguish a fire.
US11420080B2	Secure liquid consumption face covering A secure liquid consumption face covering is created for the general public that is flexible so that the user does not need to remove or open a mask when thirsty or hungry to consume liquid. Through a tube attached with connector(s) and lock(s) to the mask and with an optional disposable straw unit, the wearer can drink liquid from any vessel easily without taking the mask off or breaking the seal of the mask around the user's nose and mouth.
US11420078B2	Implantable ultrasound generating treating device for spinal cord and/or spinal nerve treatment, apparatus comprising such device and method An implantable ultrasound generating treating device (12) to induce spinal cord or spinal nerves treatment, suitable for implantation in the spinal canal and comprises an elongate support member (22, 32) and an array of several treatment transducers (20) distributed along the elongate support member. The several treatment transducers (20) comprise radial transducers emitting an ultrasound treatment beam oriented radially, wherein the treatment transducers (20) have a resonant frequency comprised between 0.5 and 4 MHz. The device has articulating portions so that the implantable device can adapt its shape to a curved elongation path. Also disclosed is an apparatus including the implantable ultrasound generating treating device and methods comprising inserting the implantable ultrasound generating treating device (12) inside the spinal canal of the spine of the patient.
US11420075B2	System and method for reconstructing image volumes from sparse two-dimensional projection data A system and method for acquiring medical images of a subject includes performing two-dimensional (2D) scan of a subject using a medical imaging system to acquire 2D data from at least two view angles and generating a three-dimensional (3D) model of the subject from the 2D data. The method also includes extracting desired images of the subject from the 3D model. The desired images are at view angles different from the at least two view angles. The method further includes prescribing an imaging study of the subject using the desired images of the subject to control at least one of a signal-to-noise ratio of data acquired using the imaging study or a dose of ionizing radiation delivered to the subject during the imaging study. The method also includes performing the imaging study using the medical imaging system to acquire imaging data from the subject and reconstructing images of the subject from the imaging data.
US11420074B2	System for detecting stent slippage The invention provides a method for locating radioactive material implanted in a living body, the method having the steps of implanting a stent into the body, the stent containing the radioactive material; imaging the body to determine a first position of the stent relative to remote points on the body; determining a second position of the stent at a second time later than the time of the implanting step; and measuring the distance between said first position and said second position. Also provided is a system for determining movement of a radiation source implanted in a living body, the device having a radiographic film overlaying a region of the body so as to oppose the radiation source, whereby the film is positioned relative to a reference point on the body; a grid disposed between the film and the body; and a radio-opaque substrate overlaying the film.
US11420070B2	System and method of generating high voltage variable frequency electromagnetic radiation In a high voltage, variable frequency radiation generation system, a carrier signal supplied to a primary coil of a transformer is varied, e.g., turned ON and OFF at variable frequencies. The ON duration and/or the average amplitude of the carrier signal may also be varied. Moreover, the carrier signal may be modulated using an audio signal. The parameters to control the variation of the carrier can be provided as a recipe via a software application. A server can provide different types of apps providing different control features. The server may also collect user characteristic data and recipe usage data, and may facilitate exchange of these data and may recommend recipes based on a particular user characteristic.
US11420065B2	Neural stimulation system to deliver different pulse types A method, electrical tissue stimulation system, and programmer for providing therapy to a patient are provided. Electrodes are placed adjacent tissue (e.g., spinal cord tissue) of the patient, electrical stimulation energy is delivered from the electrodes to the tissue in accordance with a defined waveform, and a pulse shape of the defined waveform is modified, thereby changing the characteristics of the electrical stimulation energy delivered from the electrode(s) to the tissue. The pulse shape may be modified by selecting one of a plurality of different pulse shape types or by adjusting a time constant of the pulse shape.
US11420062B2	Neurostimulation system for central nervous stimulation (CNS) and peripheral nervous stimulation (PNS) The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stimulation module, at least one Peripheral Nervous System (PNS) stimulation module, wherein at least one of the components of the neuromodulation and/or neurostimulation system is implantable.
US11420061B2	Biased neuromodulation lead and method of using same A neuromodulation lead that is biased towards a substantially omega shape when fully deployed is provided. The neuromodulation lead includes a left set of electrodes disposed on a left portion of the lead body of the neuromodulation lead and a right set of electrodes disposed on a right portion of the lead body of the neuromodulation lead. The neuromodulation lead can be positioned in the plane between the genioglossus muscle and the geniohyoid muscle.
US11420059B1	Personalized network searching Personalized network searching, in which a search query is received from a user, and a request is received to personalize a search result. Responsive to the search query and the request to personalize the search result, a personalized search result is generated by searching a personalized search object. Responsive to the search query, a general search result is generated by searching the general search object. The personalized search result and the general search result are provided to a client device, an advertisement is selected based at least in part upon the personalized search object, and the advertisement, the personalized search result, and the general search result are displayed.
US11420058B2	Nerve root and dorsal root ganglion stimulation from the lateral epidural space A system comprises a bendable, pre-formed lead body operable to be implanted proximate a neural pathway of a patient. A first electrode comprising a plurality of first segments at a first longitudinal location of the lead body is configured to be positioned at a lateral epidural region proximate at least one nerve root of the patient, and a second electrode comprising a plurality of second segments at a second longitudinal location of the lead body is configured to be positioned along a midline of the patient's spinal column. The system further includes a signal generator electrically coupled to at least one of the first and second electrodes and a processor coupled to the signal generator and operable to apply a stimulation signal to at least one of the first and second electrodes.
US11420055B2	Systems and methods for determining a stapedius reflex threshold based on electro-acoustic stimulation A stapedius reflex threshold determination system directs a cochlear implant and a loudspeaker to apply a first electro-acoustic stimulation event to a patient, and determines that a first evoked response that occurs within the patient in response to the first electro-acoustic stimulation event has a level within a predetermined threshold amount of a baseline evoked response level. Based on that determination, the system detects that a stapedius reflex within the patient is not triggered. The system also directs the cochlear implant and the loudspeaker to apply a second electro-acoustic stimulation event to the patient, and determines that a second evoked response that occurs within the patient in response to the second electro-acoustic stimulation event has a level at least the predetermined threshold amount lower than the baseline evoked response level. Based on this determination, the system detects that the stapedius reflex within the patient is triggered.
US11420054B2	Device and method to modulate a nervous system structure to non-invasively and non-destructively inhibit nervous signaling The present disclosure is directed to a system and method modulating targeted neural and non-neural tissue of a nervous system for the treatment of head-and-face pain. Electrical stimulation is delivered transcutaneously to the treatment site that modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting nervous signaling and the perception of pain.
US11420052B2	Device and method for neuromodulation treatment The invention provides a device for stimulating peripheral nerves, comprising a memory, at least one electrode attached to the patient's body for generating pulses, and a control unit connected with an electrode for setting at least one electrode pulse parameter. The device further includes a detector of response to neuromodulation connected with a control unit for transmitting information on a frequency of movement of at least a part of the body to the control unit, and a controller connected with the control unit for acquiring a user input. The control unit of the device further sets flow of current of electrode pulses automatically, depending on information on a frequency value of movement of a part of the body. The invention further provides a method for treating the syndromes of an overactive bladder using a neuromodulation device. And method of collecting information of such devices.
US11420048B2	Skin rejuvenation device A device and method for rejuvenating skin includes a power supply adapted to generate a voltage and an applicator. The applicator includes a first node and a second node, wherein the first node is adapted to be configurable between a positive electrode or electrically isolated from the power supply, and wherein the second node is adapted to be configurable between a negative electrode or electrically isolated from the power supply. The power supply delivers a current through the first node when the first node is configured as the positive electrode and current returns to the power supply through the second node when the second node is configured to be the negative electrode.
US11420045B2	Leads having sidewall openings, and associated systems and methods The present technology is generally directed to spinal cord modulation leads having one or more sidewall openings configured for inserting stylets to steer and/or position the leads within a patient and/or with respect to a pulse generator, and associated systems and methods. In some embodiments, sidewall opening is generally positioned in an intermediate portion of the lead and is operatively coupled to a lumen extending distally to a distal end of the lead, and/or proximally to a proximal end of the lead.
US11420042B2	Systems and methods for delivering neurostimulation using exogenous electrodes The present disclosure provides systems and methods for exogenous neurostimulation. An exogenous neurostimulation system includes an electrode pad comprising a plurality of electrodes configured to be applied to skin of a patient, and a pulse generator communicatively coupled to the electrode pad, the pulse generator operable to generate burst waveforms for delivery to the skin of the patient via the electrode pad.
US11420040B2	Methods, system, and computer readable media for a rotational speed-based control system for ventricular assist devices Methods, systems, and computer readable media for controlling ventricular assist devices are disclosed. In some embodiments, the method includes receiving at least one reference pump speed differential associated with a pump of a ventricular assist device; determining a filtered pump speed differential associated with the pump of a ventricular assist device; and adjusting, using a feedback based controller algorithm, current to the pump based on the at least one reference pump speed differential and the filtered pump speed differential. In some embodiments, the system includes a controller implemented using the non-transitory computer readable medium, wherein the controller is configured for receiving at least one reference pump speed differential associated with a pump of a ventricular assist device; determining a filtered pump speed differential associated with the pump of a ventricular assist device; and adjusting current to the pump based on the at least one reference pump speed differential and the filtered pump speed differential.
US11420039B2	Tree-based data exploration and data-driven protocol A method for providing a treatment recommendation to a physician for treating a patient is disclosed. The method comprises determining, from a processor in communication with a patient data repository, a first treatment recommendation based on a combination of selected patient demographics from the patient data repository applicable to the patient, and operational parameters of a plurality of ventricular assist devices (VADs) suitable for treating the patient, the first treatment recommendation having a first survival rate and comprising the use of a first VAD. The method then obtains a first signal from using the first VAD on the patient. The method then determines a second treatment recommendation based on the first signal and the first treatment recommendation, the second treatment recommendation having a second survival rate. The method then provides the second treatment recommendation to the physician if the second survival rate is higher than the first survival rate.
US11420038B2	Breaker device for acting onto a closure element of a medical tubing A breaker device (1) for acting onto a closure element (40) of a medical tubing (4) comprises a drive arrangement (2) having an electric drive device (20) and a drive element (23) driven by the drive device (20), and a breaker module (3) which is arrangeable on the drive arrangement (2). The breaker module (3) comprises a housing (30), a movable part (31) movably arranged on the housing (30) and a breaking element (315) for acting onto the closure element (40) of the tubing (4), wherein the breaker module (3) in an attached state is placed on the drive arrangement (2), the drive element (23) being in operative connection with the movable part (31) in the attached state such that a movement of the drive element (23) causes the movable part (31) to move for actuating the breaking element (315). A control device (5) serves for controlling the electric drive device (20) for driving the drive element (23). Herein, the control device (5) is constituted to control, during a detection routine, the electric drive device (20) to drive the drive element (23) in order to move the movable part (31), wherein the control device (5) is further constituted to analyse at least one feedback signal received during the detection routine for determining a type of the breaker module (3), the feedback signal being indicative of a movement of the movable part (31) during the detection routine.
US11420030B2	Methods and systems for delivering substances into luminal walls Angioplasty and other dilatation devices are provided with scoring elements which incorporate a drug to be delivered to a body lumen, typically a blood vessel. The scoring elements have drugs and other active substances coated over a portion thereof or incorporated within internal structure of the element so that the drug is released into the luminal wall closely associated diseased regions of the body lumen as the scoring structure is radially expanded into the wall.
US11420029B2	Inflatable medical devices An inflatable structure for use in biological lumens and methods of making and using the same are disclosed. The structure can have an inflatable balloon encircled by a shell. The shell can have proximal and distal tapered necks, longitudinally-oriented flutes, and apertures at the proximal and distal ends of the shell. The apertures can be recessed in the flutes in the necks. The shell can also have fiber reinforced walls.
US11420027B2	Sheath The present application includes a sheath that is suitable for use in a variety of medical procedures. In one or more implementations, the sheath includes a shunt member, and a curvable portion. The curvable portion may be configured in various orientations to facilitate an intervention, such as a hemodialysis intervention, or the like, by an operator. The curvable portion may be configured to bend between a substantially straight configuration and a curved configuration. In implementations, the sheath may be configured to have detachable and/or interchangeable components (e.g., shunt member, curvable portion, etc.).
US11420023B2	Stabilizing device having a snap clamp A retainer includes a first arcuate wall and a second arcuate wall that together define a channel designed to receive a medical article. The retainer has an open configuration wherein a first end of the first arcuate wall is spaced away from a first end of the second arcuate wall, and a closed configuration wherein the first end of the first arcuate wall is adjacent the first end of the second arcuate wall. A second end of the first arcuate wall opposite the first end of the arcuate wall may be spaced away from the base in the open configuration and pressed against the base in the closed configuration. The retainer also may include a first support and a second support fixed to the base, and a first and second flexible coupling connecting the first and second supports to the first and second arcuate walls.
US11420018B2	Catheter-based user interface device for remote control of display images In the present invention, an interface control module for controlling a mapping/imaging/recording system is provided for placement on a catheter control handle. The interface control module includes control elements that are operably connected to the mapping/imaging/recording system in order to control various functions of the imaging/recording system relating to images represented on a display forming a part of the mapping/imaging/recording system. The interface control module can be integrated with the catheter control handle or can be formed as a separate component that is releasably attachable to the catheter control handle to enable a use to operate the mapping/imaging/recording system from the catheter control handle being utilized in an interventional medical procedure.
US11420017B2	Catheter wetting devices A urinary catheter wetting apparatus (121) has a chamber defined by a forward section (123) opposite to a rearward section (125) each having an aperture (143,153) of which are axially aligned. A catheter tube is connected to a connector (161), the latter of which spans the chamber and initially seals the two apertures. The connector is slideable through the first facial surface (129) of forward section and the second end wall (131) of the rearward section so the catheter tube can be drawn through the chamber. A wetting applicator (151) holding a wetting agent is disposed in the chamber. Upon use, the connector passes through the chamber, applying pressure to the wetting applicator, thereby releasing the wetting agent from the wetting applicator and onto the catheter tube as it follows the connector through the chamber.
US11420013B2	Vibration suppression apparatus Systems and methods for reducing vibrations perceived by a human due to an artificial heart valve include a vest that is wearable around a torso of the human, a plurality of sensors mounted to the vest, a plurality of vibration-generating actuators mounted to the vest, and a controller. The plurality of sensors detects vibrations in the human generated by the artificial heart valve. The controller is operable to receive signals representing the detected vibrations from the plurality of sensors, and is operable to produce anti-vibration signals that substantially attenuate the detected vibrations. A first sensor of the plurality of sensors is located near a first vibration-generating actuator of the plurality of vibration-generating actuators to form a sensor/actuator set. In the sensor/actuator set, the anti-vibration signals generated by the controller for the first vibration-generating actuator correspond to the vibrations detected by the first sensor.
US11420011B2	Sleep assistance device A sleep assistance device includes a contactless biometric sensor, a processor, memory, and a speaker. The processor detects a user's sleep state by reading signals from the contactless biometric sensor. The processor may then initiate a wind-down routine upon detecting a sleep-readiness state, including playing relaxing sounds or playing a respiration entrainment sound. The processor may also play noise-masking sounds upon detecting that a user has fallen asleep and seamlessly transition between the sounds played during the wind-down routine and the noise-masking sounds.
US11420008B2	Vent and vent adaptor for patient interface A vent system for use during respiratory therapy with a flow of pressurized gas may provide a continuous vent flow of gas. The vent system may include a vent housing having an outer wall; an inner wall, the inner wall defining an inlet for the flow of gas; and a base positioned between the outer wall and the inner wall, the base having at least one first orifice and at least one second orifice. The vent system may include a membrane, the membrane being shaped and dimensioned such that the membrane does not cover the at least one first orifice to allow the vent flow through the at least one first orifice, and the membrane being shaped and dimensioned such that in a first position the membrane is positioned over the at least one second orifice to allow the vent flow through the at least one second orifice.
US11420004B2	Mask assembly A nasal assembly for delivering breathable gas to a patient includes a frame having an integrally formed first connector portion. A nozzle assembly includes a gusset or base portion and a pair of nozzles. At least one inlet conduit is structured to deliver breathable gas into the frame and nozzle assembly for breathing by the patient. A pair of second connector portions are removably and rotatably connected to respective first connector portions of the frame and are in communication with respective inlet conduits, e.g., directly or via angle connectors. A headgear assembly is removably connected to the pair of second connector portions and/or the angle connectors so as to maintain the frame and the nozzle assembly in a desired adjusted position on the patient's face.
US11420003B2	Supplemental gas delivery device for mask assembly A supplemental gas delivery device is described for a mask assembly having at least one supplemental gas port, the at least one supplemental gas port including an aperture in communication with an interior of the mask assembly. The mask assembly may include an aperture communicating with an interior of the mask assembly, and a cannula for communicating with the supplemental gas port. The cannula is positioned to deliver supplemental gas adjacent to the patient's nares and/or mouth, to increase an efficacy of treatment for the patient by more directly applying the flow of supplemental gas to the patient's nares. An optional bridging portion may be included to provide a connection between supplemental gas port and the cannula.
US11420001B2	Mask system A mask system includes a cushion adapted to seal with a face of a patient. In one form an unobtrusive full-face masks system is provided which is comfortable and has a wide fit range. The cushion may include a sealing structure and a supporting structure. The supporting structure may include gaps or spacing in a nasal bridge region (NBR) and/or a lip region (CHN).
US11419998B2	Device for securing airway and ventilation during robotic surgery of the head and neck There is provided an LMA mask integrated for robotic surgery with ventilation or anesthesia tubes and for receiving the robot head with medical instruments through the mask. The inflatable cuff of the mask surrounds the robot head and ventilation so that the items necessary for surgical procedures are contained within a compact defined area. Increased maneuverability and visibility for the medical professional. Integration of the mask with processes for ventilation or anesthesia by accessories is also provided.
US11419996B2	Device for respiration by using a tubus The invention relates to a breathing apparatus, which comprises a respiratory gas source, a control unit and a device for connection to a tube. The control unit of the apparatus is connected to at least one sensor for recording a measurement value, the control unit comprising a pressure generator for setting at least two pressure levels generated by the respiratory gas source and a memory for measurement values, and the sensor being configured for measuring a flow and being coupled to an analyzer which determines the volume. The apparatus operates as specified in the claims.
US11419994B2	Vaporization device having channel structure The present application relates to a vaporization device. The vaporization device includes a housing, a heating component, a heating component cap, a heating component base, and a first sealing element disposed on the heating component cap. The housing and the first sealing element define a liquid storage compartment, and the heating component and the heating component base define an vaporization chamber. The heating component cap includes a first opening on a first surface, a second opening on a second surface, and a first channel passing through the first opening and the second opening. The first sealing element covers the first opening, and the second opening is in fluid communication with the vaporization chamber.
US11419989B2	Removal member for removing a needle protective cap A removal member for removing a needle protective cap includes a housing having a longitudinal axis and receiving the cap along an insertion direction, the housing having a first support area and a second support area the first area being carried by a blocking element, movable relative to the housing between a cap insertion configuration, in which the orthogonal projections of the first and second areas in a transverse plane substantially perpendicular to the longitudinal axis are separated by an insertion distance, and a cap blocking configuration, in which the first and second areas are located in separate transverse planes, and in which the orthogonal projections of the first and second areas in said transverse plane are separated by a blocking distance less than the insertion distance and adapted to block the translation of the cap relative to the removal member in a removal direction opposite to the insertion direction.
US11419984B2	Compressible reservoir for liquid medicament A reservoir for a liquid medicament is described. The reservoir includes a first boundary portion and a second boundary portion forming a cavity to receive the medicament. The first boundary portion is substantially opaque and flexible. The second boundary portion is substantially transparent and rigid.
US11419981B2	Priming apparatus and method A priming system including a resilient chamber having flexible walls and a first check valve in a first fluid pathway between the resilient chamber and a fluid reservoir such that a fluid flows through the first check valve only in a direction from the fluid reservoir toward the resilient chamber and the fluid returns to the fluid reservoir through a second fluid pathway between the resilient chamber and the fluid reservoir upon compression of the walls of the resilient chamber.
US11419977B2	Self-orienting syringe and syringe interface A medical injector including at least one syringe port for engaging at least one syringe and having a locking mechanism. The locking mechanism enables the syringe to self-align with the syringe port for locking engagement upon insertion of the syringe into the syringe port and to axially eject the syringe from the port upon rotational disengagement of the syringe from the port.
US11419974B2	System and method for the effective, reliable and foolproof delivery of controlled amounts of a medical fluid A method for using CO2 as a contrast material in medical imaging procedures is disclosed. The method includes providing a source of pressurized CO2. The step of providing includes connecting the source of pressurized CO2 to a compressed gas unit for controlling delivery of the CO2. The method also includes regulating pressure of the CO2 delivered by the compressed gas unit, transmitting the pressurized CO2 from the compressed gas unit to a control valve assembly for delivery to a patient in controlled dosages, and sequentially processing the CO2 with the control valve assembly and delivering the CO2 to the patient as a contrast media.
US11419973B2	Medical/surgical lavage unit with a pump that includes a bellows chamber and a supplemental chamber A lavage unit may include a handpiece configured to house a pump to which an irrigation tube is connected. The pump may include a bellows defining a pump chamber. When the bellows is reciprocated by a linkage, the bellows draws irrigation fluid from the irrigation tube into the pump chamber and then discharges the fluid out of the pump chamber through an outlet. The pump further includes a section formed from compressible or flexible material that defines a supplemental chamber. The linkage is connected to said pump to alternatively compress the bellows forming the pump chamber and the material forming the supplemental chamber. During the movement of the linkage a valve located between the pump chamber and the supplemental chamber reciprocates with the linkage.
US11419972B2	Wound therapy device, kit, and method for improved application to wounds on complex geometries A negative pressure wound therapy device, kit, and method are provided for improved treatment of wounds on complex three-dimensional anatomies. The device includes a conformable manifold made of a porous and permeable material with a pattern of cuts designed to transform the manifold from a relaxed, planar state to a pliable three-dimensional state when extended along the lateral axis. The kit further may include a wound interface layer, an adhesive, breathable drape, and a pneumatic connection to a negative pressure wound therapy device. Finally, a method for treating wounds using reduced pressure and the presently disclosed kit is provided.
US11419970B2	Blood filter Provided is a blood filter that resists deterioration in properties as a result of electron beam sterilization treatment performed before or during use as a blood filter, has durability, dimensional stability, and chemical resistance at excellent levels, also has biocompatibility, and resists deterioration in properties even upon the electron beam sterilization treatment. The blood filter according to the present invention includes a nonwoven fabric made of PEEK fibers. Preferably, the blood filter according to the present invention has an average pore size of 3 to 280 μm and has a porosity of 15% to 70%; and the PEEK fibers have an average fiber diameter of 10 μm or less.
US11419969B2	Neonatal and pediatric blood filtration system A blood filtration system may to couple to an infusion pump that is external to the blood filtration system. The blood filtration system may include a blood circuit, for instance a variable-volume blood circuit. An infusion port may be in communication with the blood circuit and may receive an infusion fluid pumped by the infusion pump. A filtration pump may extract a filtrate fluid from a filter. The filtrate fluid may include filtered plasma constituents. A fluid characteristic sensor may measure one or more of pressure or flow rate of the infusion fluid pumped by the infusion pump. A controller may monitor the fluid characteristic sensor to determine a change in the pressure or flow rate of the infusion fluid. The controller may modulate a speed of the variable-speed filtration pump based on the change in the pressure or flow rate of the infusion fluid.
US11419963B2	Blood purification apparatus A blood purification apparatus with a blood circuit that allows a patient's blood to extracorporeally circulate and a blood purifier connected to the blood circuit and that purifies the blood in extracorporeal circulation are attachable, the blood purification apparatus including a dialysate introduction line through which dialysate is introduced into the blood purifier; a dialysate drain line through which waste dialysate resulting from blood purification performed by the blood purifier is drained from the blood purifier; and a concentration-detecting unit that detects a concentration of a predetermined substance in the waste dialysate flowing through the dialysate drain line. The blood purification apparatus includes a control unit that establishes a state of equilibrium where the concentration of the predetermined substance in the waste dialysate flowing through the dialysate drain line and a concentration of the predetermined substance in the blood flowing through the blood circuit are equal or approximate to each other; a storage unit that stores a value detected by the concentration-detecting unit in the state of equilibrium as an equilibrium value; and a clear-space-calculating unit that calculates clear space in accordance with the value detected by the concentration-detecting unit and the equilibrium value stored in the storage unit, the clear space being an index representing a volume of purification of a patient achieved by blood purification treatment.
US11419960B2	Portable UV-sanitizing box The present disclosure provides a portable UV-sanitizing box, providing a lower shell, an upper shell hinged to the lower shell, a sterilizing assembly having an ultraviolet ray lamp assembly arranged on the upper shell, a first conductive component arranged on the lower shell for electrically connecting to the first printed circuit board assembly, a first magnetic member adjacent to the first conductive component mounted on the lower shell, a second conductive component arranged on the upper shell for electrically connecting to the ultraviolet ray lamp assembly, a second magnetic member corresponding to the first magnetic member adjacent to the second conductive component mounted on the lower shell, the second magnetic member and the first magnetic member are magnetically attracted to each other.
US11419959B2	Portable ultraviolet sterilization container The invention discloses a portable ultraviolet sterilization container, which comprises a sterilization container body, the sterilization container body has an article storage cavity and a cover, and the sterilization container body is further provided with an illumination device, a heating air duct and a control system. The control system is electrically connected to the illumination device and the heating air duct for controlling the illumination device and the heating air duct to release ultraviolet light and hot air to the article storage cavity, wherein the illumination device comprises a plurality of light-emitting devices which are fixed to a plurality of cavity walls of the article storage cavity. The inner circulation of the heating air duct is from the article storage cavity, through the interior of the cavity wall of the article storage cavity, and then to the article storage cavity.
US11419956B1	Light fixture with removable auxiliary light modules A light fixture includes a housing defining a channel and an insert lighting module. The insert lighting module includes an insert housing, a visible light engine coupled to a bottom portion of the insert housing for emitting visible light for general illumination, and an auxiliary light module coupled to the insert housing and including an auxiliary light engine for emitting germicidal light effective in deactivating pathogens. A top portion of the insert lighting module may be positioned within the channel and the insert lighting module may be coupled to the housing. The auxiliary light module may be uncoupled and removed from the insert housing by performing the steps of: uncoupling the insert lighting module from the housing and removing the insert lighting module from the channel, and uncoupling the auxiliary light module from the insert housing and removing the auxiliary module from the top portion of the insert housing.
US11419955B2	Multimodal silica-based nanoparticles The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo. In order to target a specific cell type, the nanoparticle may further be conjugated to a ligand, which is capable of binding to a cellular component associated with the specific cell type, such as a tumor marker. In one embodiment, a therapeutic agent may be attached to the nanoparticle. To permit the nanoparticle to be detectable by not only optical fluorescence imaging, but also other imaging techniques, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), bioluminescence imaging, and magnetic resonance imaging (MRI), radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle.
US11419953B2	Reduced metastable complex macrocyclic contrast agents Gadolinium based contrast agents (GCA) incorporating linear ligand chelation are fundamentally different from GCAs incorporating macrocyclic ligands. The macrocyclic\GCAs are synthesized by pathways characterized by the formation of a sequence of metastable complexes before obtaining the final stable complex. The synthesis of linear GCAs do not form metastable complexes. Commercial macrocyclic GCAs contain unstable metastable complexes. These metastable species are not regulated and quickly release free Gd3+ ions upon administration into the body. Gadolinium based contrast agents with near zero metastable species content and methods of synthesizing the same are disclosed. Gadolinium based contrast agents with long dissociation time in the body, and low free Gd3+ ion formation are obtained using a synthesis method which departs in novel ways from the traditional free Gd3+-based synthesis methods.
US11419951B2	Peptide-based cancer imaging agents Disclosed are compositions and methods relating to novel tumor targeting peptides.
US11419946B2	Heterobifunctional monodispersed polyethylene glycol and conjugate using same A heterobifunctional monodispersed polyethylene glycol represented by formula (1) which has two adjacent monodispersed polyethylene glycol side chains and does not have a chiral center in the molecular structure: wherein X1 and Y1 are each an atomic group containing a functional group capable of forming a covalent bond upon a reaction with a functional group present in a biofunctional molecule. R1 is a hydrocarbon group or the like. n is an integer of 3 to 72. A1 represents -L1-(CH2)m1— or the like, L1 and L2 represent each an ether bond or the like, and m1 and m2 each independently represent an integer of 1 to 5. B1 represents -L3-(CH2)m3— or the like, L3 and L4 represent an amide bond or the like, and m3 and m4 each independently represent an integer of 1 to 5. Also disclosed is an antibody-drug conjugate including the heterobifunctional monodispersed polyethylene glycol.
US11419945B2	Antigen binding proteins The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
US11419942B2	Angiotensinogen (AGT) iRNA compositions and methods of use thereof The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the angiotensinogen (AGT) gene, and methods of using such RNAi agents to inhibit expression of AGT and methods of treating subjects having an AGT-associated disorder, e.g., hypertension.
US11419941B2	Vaginal hydrogel The vaginal hydrogel may be a composition which includes a glycosaminoglycan, a reactive molecule, and, in some embodiments, a therapeutic agent. The glycosaminoglycan and the reactive molecule may include either thiol groups or thiol reactive sites and have a pH that is within a range of a normal vaginal environment. Some of the thiol groups may interact with the vaginal mucosa and allow the hydrogel to remain in the vagina for a longer period than existing compounds intended for intravaginal administration. Therapeutic agents may be included in the composition. In these embodiments, the hydrogel acts as a vehicle which delivers the therapeutic agent.
US11419936B2	Immunoglobulin preparation and storage system for an immunoglobulin preparation The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 μmol/l.
US11419935B2	Immunotherapy method comprising administering a combination of immune effector cells and non-target hematopoietic cells The invention provides a system that comprises pharmaceutical agents for use in immunotherapy for reducing the side-effects of an antigen-recognizing receptor against antigen-expressing non-target cells in an individual. The system includes an antigen-recognizing receptor that specifically recognizes an antigen on target cells and at least on one hematopoietic cell type in the individual. The antigen-recognizing receptor is exemplified by chimeric antigen receptors (CAR) be expressed on the surface of an immune effector cells. The system also includes hematopoietic cells resistant to recognition of the same antigen by the antigen-recognizing receptor.
US11419933B2	Pharmaceutical composition comprising bispecific antibody constructs The present invention provides novel and stable pharmaceutical compositions comprising bispecific single chain antibody constructs, cyclodextrins and a buffer.
US11419931B2	Compositions comprising bacterial strains The invention provides compositions comprising bacterial strains for stimulating the immune system and treating and preventing diseases.
US11419929B2	Alphavirus neoantigen vectors Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.
US11419924B2	Immunotherapeutic compositions for the treatment of Alzheimer's disease A safe and effective vaccine to prevent, slow, halt or reverse progression of Alzheimer's disease in human patients is disclosed. The vaccine includes Aβ1-42 or an beta amyloid self epitope (e.g. Aβ1-15, or other 7-mer or 15-mer peptide epitopes derived from Aβ1-42) conjugated to an immunogenic carrier formulated in a water-in-oil Th2-biased adjuvant/delivery system.
US11419922B2	Treatment of post-traumatic stress disorder using botulinum toxin A Methods are disclosed for treating post traumatic stress disorder (PTSD) in a subject. The methods include administering a therapeutically effective amount of a neurotoxin to a corrugator supercilii and/or a procerus muscle of the subject to cause paralysis of the corrugator supercilii and/or a procerus muscle in the subject, thereby treating PTSD. The neurotoxin can be Botulinum toxin A, such as at a dose of about 20 to about 50 units of Botulinum toxin A.
US11419919B1	High-purity adrenocorticotropic hormone, analogue and a large-scale preparation method thereof The invention belongs to the technical field of polypeptide preparation methods, and in particular relates to a high-purity ACTH (human sequence) or analogue and large-scale preparation method thereof. The main steps include: amino acids are coupled from the C-terminal to the N-terminal by Fmoc solid-phase synthesis method to obtain the crude ACTH (human sequence) or analogue peptidyl-resin with protective groups, wherein the reaction temperature of C-15 peptide synthesis is 40-60° C. After cleavge and precipitation, the crude product of ACTH (human sequence) or analogue is obtained, and then the high-purity product is obtained by liquid chromatography. The chromatographic purity of ACTH (human sequence) or analogue prepared by the invention is more than 99%, the stability is good, and the yield of the target peptide is ≥63%.
US11419914B2	Safe desmopressin administration Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients. The dispensers of the invention may be used in the treatment of nocturia, primary nocturnal enuresis, incontinence, urinary frequency, diabetes insipidus, or any disease or syndrome where desmopressin therapy is useful or where safe temporary suppression of urine production may lead to beneficial health effects or increased convenience in voiding control.
US11419911B2	Pain-relieving composition A pain-relieving composition for topical administration and processes for preparing and using the same. The pain-relieving composition comprises beeswax, coconut oil, and peppermint essential oil, and, at a minimum, does not comprise dimethylsulfoxide, methylsulfonylmethane, a non-steroidal anti-inflammatory drug, an analgesic, an anesthetic, olecanthal, an olecanthal-related compound, potassium aluminum sulfate, stearic acid, camphor, cayenne, a non-essential oil in addition to the coconut oil, or water; and does not further comprise both Eucalyptus essential oil and lavender essential oil. The processes for preparing such pain-relieving compositions comprises providing beeswax, coconut oil, and peppermint essential oil, melting the beeswax and coconut oil to form a molten beeswax and coconut oil mixture, and combining the peppermint essential oil with the molten beeswax and coconut oil mixture.
US11419909B2	Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract The present disclosure provides compositions and methods for making and using topical compositions comprised of an isotonic, biome-friendly solution containing xylose and/or a Salvia extract. The compositions are useful for, for example, maintaining or enhancing female lower reproductive tract (LRT) homeostasis and physiological function. In particular, topical compositions of this disclosure can be formulated for use as a freshening, menopausal, fertility, and/or perineal composition.
US11419906B2	Method and composition for therapeutic management of gluten intolerance The present invention discloses the potential of probiotic bacteria Bacillus coagulans individually or in combination with multi-enzyme complex for reducing gluten content in foods rich in gluten and for the increased utilization of gluten. The invention further discloses a method for the management of gluten intolerance using composition comprising Bacillus coagulans and multi-enzyme complex in mammals.
US11419901B2	Porphyromonas gingivalis immune modulators and uses thereof A heat killed Porphyromonas gingivalis bacterium expressing a homogenous lipid A structure having a molecular negative mass ion of 1368, 1435/1449, or 1690/1768 is used as an immunomodulator. The immunomodulator may be used in combination with an antigen of interest to potentiate or restrain a host immune response toward the selected antigen.
US11419890B2	Compositions prepared from poultry and methods of their use Broth compositions prepared from poultry are disclosed. Selected poultry raw materials are processed to obtain a broth having high protein content. Certain specific amino acids are present in relatively higher concentration as compared to home-made broth and other commercial products. The disclosed broth compositions are effective in preventing and/or treating joint diseases and may also provide other nutritional and health benefits.
US11419887B2	Vehicle for delivering a compound to a mucous membrane and related compositions, methods and systems PSA is delivered to the host by outer membrane vesicles (OMVs), secretion structures that target bacterial molecules to host cells. Purified OMVs direct the in vitro differentiation of functional Tregs with potent suppressive activity in a PSA dependent manner. Treatment of animals with OMVs containing PSA prevents experimental colitis and suppresses pro-inflammatory cytokine responses in the gut, and indicate that compositions, medicaments, and methods useful for the treatment of inflammation, and more particularly, inflammatory bowel diseases.
US11419885B2	Compositions for use in the prevention or treatment of URT infections in infants or young children at risk A composition contains at least one fucosylated oligosaccharide, for use in preventing and/or treating a URT infection in an infant or young child fulfilling at least one of the following criteria: i) the infant or young child is born from a non-secretor mother and/or is fed with a mother's milk deficient in at least one fucosylated oligosaccharide, ii) the infant or young child has at least one sibling, and iii) the infant or young child was born by C-section.
US11419884B2	Compositions comprising HMOS, their production and use for the prevention and/or treatment of viral and/or bacterial infections The present disclosure relates to synthetic mixtures of certain human milk oligosaccharides and uses thereof. Particular mixtures provided herein include: lacto-N-triose II, lacto-N-neotetraose, para-lacto-N-neohexaose, and, optionally, lactose; and lacto-N-triose II, lacto-N-tetraose, para-lacto-N-hexaose II, and, optionally, lactose. These mixtures are useful in the prevention and treatment of viral and bacterial infections.
US11419883B2	Inhibiting senescent processes in beta cells for the prevention of type 1 diabetes The inventor of the present disclosure has advantageously elucidated the role of senescent processes in the development of Type 1 diabetes. Genotoxic stress responses, senescence, and acquisition of a SASP condition in beta cells are drivers that progress at-risk individuals to overt Type 1 diabetes. The administration of senolytic agents to at risk individuals selectively removes senescent cells and relieves beta cells from the factors which drive the development of overt Type 1 diabetes. Accordingly, Type 1 diabetes can be prevented in at-risk individuals by the administration of senolytic compositions. Additionally, given the major role of SASP in the development of Type 1 diabetes, the inhibition of SASP factors may be used to prevent Type 1 diabetes.
US11419878B2	Medicine obtained by combining FXR agonist and ARB The present invention provides an NASH therapeutic agent including: an FXR agonist, preferably obeticholic acid or a pharmaceutically acceptable salt thereof; and an ARB or a pharmaceutically acceptable salt thereof.
US11419876B2	Mirtazapine as a pre-shipping inhibitor of bovine respiratory disease Methods for preventing feedlot bovine respiratory diseases employing mirtazapine as pre-shipment treatments are disclosed. Compositions are further disclosed. Beneficially, the methods and compositions provide safe and cost-effective management of a costly disease.
US11419875B2	Compounds and compositions for treating hematological disorders The present invention provides methods of treating hematological disorders, such as acute myeloid leukemia, using substituted heterocyclic compounds and pharmaceutically acceptable salts thereof. The compounds inhibit IRAK4 and FLT-3 kinases.
US11419871B2	Therapeutic agent for lung cancer that has acquired EGFR-TKI resistance A drug containing, as an active ingredient, a compound represented by ALK inhibitors such as brigatinib, AP26113-analog, and AZD3463 has been found to be effective against a non-small cell lung cancer having a point mutation at C797S in EGFR which has acquired a resistance to chemotherapy agents. Further, the drug used in combination with an anti-EGFR antibody demonstrates a notable suppression effect on the tumor growth. The drug has a potential to be a therapeutic agent effective against a non-small cell lung cancer which is resistant to gefitinib, a first generation therapeutic agent and osimertinib, a third generation therapeutic agent.
US11419870B2	Intermittent dosing of MDM2 inhibitor The present disclosure relates to mdm2 inhibitors for use in specific dosing schedules. It was found that if sufficiently potent or, in alternative, sufficiently high dose of a Mdm2 inhibitor is used, it can cause antineoplastic effect by triggering much longer lasting antiproliferative mechanism in cells. The long lasting effect can sustain for several weeks after a single dose, which eliminates the need for daily treatment and allows administering the Mdm2i intermittently. A treatment with the intermittent dosing schedule of a Mdm2 inhibitor can be combined with a daily treatment of the Mdm2i or with another pharmaceutically acceptable ingredient.
US11419869B2	Dosage forms and regimens for amino acid compounds The invention relates to dosage forms for daily administration of compounds of formula (A) and formula (I): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).
US11419868B2	Low dose product and method for treating diarrhea A method of treating diarrhea in a patient includes administering a dose of 2.0-7.0 mg of cetirizine and 3.0-15.0 mg of famotidine.
US11419866B2	Pharmaceutical composition for sustained release delivery of buprenorphine The present invention is directed to a depot composition for sustained release delivery of buprenorphine with enhanced stability and bioavailability. The composition is an injectable, low viscosity liquid and can form a depot in situ capable of delivering therapeutic level of buprenorphine over a period of time from one week to 3 months.
US11419865B2	Method for inducing a sustained immune response A method for inducing a sustained immune response in humans or animal patient suffering from human immunodeficiency virus (HIV) acquired immune deficiency syndrome (AIDS, autoimmune disease, cancer, inflammation, and neurodegenerative diseases comprises daily administration to such patients a single oral tablet, rapidly dissolving film, capsule, liquid or cream dose of an Immediate release naltrexone composition comprising between about 0.01 to about 10 mg of naltrexone. In order to provide a benefit the naltrexone must be an Immediate release composition comprising between about 0.01 and about 10 mg of naltrexone.
US11419859B2	Combination therapy for treating malignancies Provided are methods and compositions for treating acute myelogenous leukemia (AML) in patients carrying an IDH1 mutation using an inhibitor of a mutant IDH1 enzyme, (S)—N—((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide in combination with cytarabine and doxorubicin or idarubicin as an induction therapy and either cytarabine or a combination of combination of mitoxantrone and etoposide as consolidation therapy.
US11419857B2	Methods and compositions for treating pain The invention features combinations of dopaminergic agents and analgesic agents useful for treating pain. In particular, the combinations feature a low ratio of dopaminergic agent to analgesic agent. The dopaminergic agent can be an agonist of the dopamine receptor D1-like family or the dopamine receptor D2-like family. Such combinations potentiate analgesia to 1) alleviate acute pain, 2) prevent the transition from acute pain to chronic pain, and 3) manage chronic pain.
US11419850B2	Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases A method administers quaternary ammonium anti-cholinergic muscarinic receptor antagonists in combination with acetyl-cholinesterase inhibitors to treat either cognitive impairment or acute delirium. This therapy results in a modification of a cognitive disorder or disease, namely a slow down in the disease progression. In one preferred embodiment, the disease is dementia with Lewy Bodies. New formulations for quaternary ammonium anti-cholinergic muscarinic receptor antagonists are also disclosed.
US11419849B1	Methods and products for adverse effects of air travel, jet lag, or a change to a sleep wake timing cycle Methods and products are provided for preventing or reducing adverse effects of air travel, jet lag, and shift switching. Doses of antioxidant, anti-inflammatory, mitochondrial support, circadian shift support, and/or other agents are administered to or by the subject at selected times, and the subject sleeps or refrains from sleep, and/or is exposed to or protected from light, for selected times.
US11419844B2	Halogenated xanthene composition and method for treating hematologic cancers A method of treating a mammalian subject having hematologic, non-tumorous cancer cells is disclosed. The method comprises the steps of: (A) administering to such a mammalian subject a therapeutically effective amount of a halogenated xanthene, a pharmaceutically acceptable salt or a C1-C4 alkyl ester thereof as a first cancer cytotoxic agent dissolved or dispersed in a pharmaceutically acceptable aqueous medium. The mammalian subject is maintained for a period of time sufficient to induce death of hematologic, non-tumorous cancer cells. A contemplated administration is typically repeated. A contemplated treatment method can also be carried out in conjunction with administration to said mammalian subject of a second therapeutically effective amount of a second, differently-acting cancer cytotoxic agent dissolved or dispersed in a pharmaceutically acceptable medium. The second cancer cytotoxic agent can be a small molecule or an intact antibody or paratope-containing portion thereof.
US11419842B2	Neutral pH compositions of Docetaxel and human serum albumin This document relates to non-covalently bound complexes including Docetaxel and human serum albumin, and to compositions comprising such complexes. This document also relates to compositions comprising Docetaxel and human serum albumin, wherein the composition is a clear aqueous solution when the composition is dissolved in an aqueous solution, and wherein the composition has a solubility in an aqueous solution of at least 10 mg/ml. This document also relates to compositions comprising Docetaxel and human serum albumin, wherein the Docetaxel and the human serum albumin in the composition have a weight ratio from about 1:50 to about 1:1000. This document also relates to compositions consisting essentially of Docetaxel and human serum albumin, wherein the Docetaxel and the human serum albumin in the composition have a weight ratio from about 1:50 to about 1:1000. The pH of the docetaxel compositions of the present disclosure is from about 5 to about 8.
US11419840B2	Compositions and methods comprising C16:1N7-palmitoleate One embodiment described herein is related to methods and compositions, such as nutraceutical formulations and dietary supplements, comprising C16:1n7-palmitoleate or derivatives thereof. The methods and compositions comprising C16:1n7-palmitoleate, or derivatives thereof, safely and effectively prevent or mitigate manifestations of cardiovascular disease, including coronary artery disease and the accumulation of cholesterol or lipid deposits in the blood vessels of a subject.
US11419835B2	Method of treatment and prevention of bacterial vaginosis Described herein are methods of reducing the risk of recurrence of bacterial vaginosis by intravaginal administration of compositions comprising L-lactic acid, polymer thickener, and preservative.
US11419831B2	Dosage forms and related therapies This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogues, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.
US11419829B2	Use of cannabidiol in combination with 5-HT2B receptor agonists or amphetamines in the treatment of epilepsy The present invention relates to the use of cannabidiol (CBD) in combination with an agonist of 5-HT2B receptors. Such a combination provides protection against the adverse effects caused by agonists of 5-HT2B receptors. The invention further relates to the use of CBD in combination5 with an amphetamine or amphetamine derivative in the treatment of epilepsy. In one embodiment the CBD is used in combination with the amphetamine derivative fenfluramine to produce a significant reduction in seizures. Preferably the CBD used is in the form of a highly purified extract of cannabis such that the CBD is present at greater than 98% of the total extract (w/w) and the other components of the extract are characterised. In particular the cannabinoid10 tetrahydrocannabinol (THC) has been substantially removed, to a level of not more than 0.15% (w/w) and the propyl analogue of CBD, cannabidivarin, (CBDV) is present in amounts of up to 1%. Alternatively, the CBD may be a synthetically produced CBD. In use the CBD in combination with an agonist of 5-HT2B receptors, amphetamine or amphetamine derivative may be formulated for administration separately, sequentially or simultaneously with the15 amphetamine or amphetamine derivative or the combination may be provided in a single dosage form. Where the CBD is formulated for administration separately, sequentially or simultaneously it may be provided as a kit or together with instructions to administer the one or more components in the manner indicated.

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