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US11408134B2 |
Paving operation control method and system
In one aspect, a method of controlling an operation of a compactor during a paving operation may include obtaining thermal image data and position data of an asphalt mat using a measuring device on a paving machine, and determining, using a controller, whether a person is on the asphalt mat based on a temperature range and the thermal image data. The method also includes determining, using the controller, a distance between the person and the compactor using the obtained position data and a position of the compactor, and generating, using the controller, a signal for reducing a speed of the compactor when the determined distance between the person and the compactor is less than a maintain speed threshold distance. In other aspects, a related system is provided for controlling a compactor during a paving operation. |
US11408132B2 |
Pedestal mounted paver heating system
Some deck or patio areas constructed of pavers mounted on adjustable pedestal supports must remain snow and ice free on their top surfaces. The pedestal-mounted paver heating system is designed to allow easy installation of electric heating cable that is positioned against the bottom surface of pavers so that heat generated by the cable is efficiently transferred up into the pavers to raise their temperature enough to prevent the accumulation of snow and ice on their top surfaces. |
US11408130B2 |
Switch element for a track carrying a rubber-tyred vehicle, track switchgear made from said elements and method for transporting passengers along a rail provided with such switchgear
The disclosure relates to a flexible switch element for a track carrying rubber-tyred trains comprising two parallel rails each having an upper running surface for the tyres and an inner side surface for supporting a continuous strip (B) for guiding the train. The switch element has at least one hinge providing the longitudinal link with an adjacent switch element. The switch element also has a set of longitudinal abutments engaging, on the one hand, with the hinge in order to adjust the relative angular orientation of the element and, on the other hand, with a pivoting bottom rod providing the connection to and the alignment with an identical switch element arranged symmetrically on the opposite side of the switch. The disclosure also relates to a track switchgear comprising the assembly of such elements and a method for transporting passengers along a track provided with said track switchgear. |
US11408128B2 |
Sheet with high sizing acceptance
A process is provided for applying sizing to a wet laid fibrous sheet that comprises providing an aqueous slurry that comprises cellulose fibers and cellulose ester staple fibers; forming the wet laid fibrous sheet from the slurry; and applying an aqueous sizing composition that comprises one or more sizing agents to the wet laid fibrous sheet. In embodiments, the cellulose ester staple fibers are present in an amount sufficient to permit the sheet to have a higher sizing composition uptake and to impart higher sizing properties to the sheet, compared to a sheet formed from a 100% cellulose fiber slurry, when processed under similar conditions. |
US11408123B2 |
Base interlining, methods for their manufacture and application thereof
The invention relates to a novel binder system and its use for bonding textile fabrics as well as products containing such bonded textile fabrics. The materials according to the invention are suitable for manufacturing base interlinings which may be used for manufacturing base interlinings for sarking, roofing and sealing membranes, particularly for manufacturing coated sarking, roofing and sealing membranes. |
US11408120B2 |
Portable shower garment washer
A portable shower garment washer is an apparatus that utilizes existing shower heads to wash garments. The apparatus includes frame assembly, an enclosure, and a washing mechanism. The frame assembly upholds the enclosure and the washing mechanism. The apparatus further includes a length-adjustable fastener that attaches the frame, and consequently the enclosure, with an existing shower head. The apparatus further includes a water supply, from an existing shower head, and the enclosure contains the water from the water supply, as well as soapy water, around the garments positioned within the enclosure. The washing mechanism provides a pre-rinse cycle, a pre-soak cycle, a rinse cycle and a drip cycle within the enclosure. The apparatus is preferably manually operated with valves but may also be automatically operated with actuators. The apparatus may further include a first inflatable bladder and a second inflatable bladder that squeeze the garments in order to facilitate drying. |
US11408118B2 |
Cloth clamping chuck and cloth handling device
A cloth clamping chuck includes a pair of chuck jaws and a driving process that rotates at least one of the pair of chuck jaws around an open-close axis x to change an opening degree of the pair of chuck jaws. The cloth clamping chuck has a catching portion which is arranged in a position out of an extension line of the chuck jaws, and in associated with the pulling operation of cloth, is caught in a portion of the cloth other than the portion clamped by the pair of chuck jaws to deflect a force applied to the clamped portion of the cloth toward a side along the open-close axis. |
US11408115B2 |
Laundry washing machine equipped with a liquid supply line
A laundry washing machine comprising a cabinet supporting a washing tub external to a washing drum adapted to receive laundry and a liquid supply line for supplying liquid into the washing tub/drum through a nozzle having a tubular portion and a sprayer portion comprising a bent zone. The nozzle comprises an obstruction arranged upstream of the bent zone. |
US11408111B2 |
Easy-to-open storage container and clothes treating machine including the same
A storage container and a clothes treating machine including the same are described. The storage container is received in a detergent supply device and includes a cover portion including a cover rear protruding portion that protrudes outward from one side thereof. The storage container includes a detergent receiving portion including a container rear protruding portion that protrudes outward from one side thereof and that is aligned with the cover rear protruding portion. A user may grip the cover rear protruding portion provided in the cover portion to easily separate the cover portion and the detergent receiving portion. In addition, the user may grip the cover rear protruding portion and the container rear protruding portion to more easily separate the cover portion and the detergent receiving portion. |
US11408110B2 |
Washing machine
A washing machine includes a water tank, a washing tub, a pulsator, a drive motor, a drive shaft, a dewatering shaft that rotates about the same axis of the drive shaft and spins the washing tub, a coupler that is mounted to move up and down along the dewatering shaft and transmits the torque of the drive motor to the dewatering shaft, a solenoid module that moves the coupler upward in a lengthwise direction of the dewatering shaft so as to cut off torque from the drive motor to the dewatering shaft or transmit the torque to the dewatering shaft, when a magnetic field is generated by applying an electric current to a coil, and a coupler guide that rotates itself or fixes the position of the coupler, by coming into contact with the coupler when the coupler moves upward in the lengthwise direction of the dewatering shaft. |
US11408107B2 |
Method for controlling washing machine
A method of controlling a washing machine that includes a tub, a drum rotatably disposed in the tub, at least one nozzle spraying water into the drum, a washing motor rotating the drum relative to the tub, and a circulation pump circulating water discharged from the tub, the method including: rotating the drum to cause laundry in the drum (i) to be raised with respect to a bottom of the drum and (ii) to fall downwards into the drum while water is supplied to the drum; spraying water through the at least one nozzle while the drum rotates; based on a first water level in the tub, controlling the circulation pump to rotate at a first rotation speed; supplying water to the drum to increase the water in the tub to a second water level; and controlling the circulation pump to rotate at a second rotation speed. |
US11408104B2 |
Footwear article including circular knit structures
An aspect of the disclosure is a footwear article. The footwear article includes a double layer knitted upper having a foot bed, an upper portion continuous with the foot bed, an ankle opening, and an inner void for receiving a foot of a wearer. The double layer knitted upper has an outer knit layer defining an exterior surface of the double layer knitted upper. The double layer knitted upper also has an inner knit layer monolithically knit to the outer knit layer. The inner knit layer has a plurality of inner knit regions that spatially correspond to the plurality of outer knit regions of the outer knit layer. The outer knit layer and the inner knit layer substantially define the foot bed and the upper portion of the double layer knitted upper. |
US11408102B2 |
Upper for an article of footwear with a lattice structure
An upper for an article of footwear may have a knitted component, where the knitted component has a first edge extending from a first side of a throat area of the upper, through a heel area of the upper, and to a second side of the throat area. At least a portion of the first edge may include a lattice structure, the lattice structuring having a first lattice band and a second lattice band, the first lattice band and the second lattice band having loops that are intermeshed in at least one location, where a plurality of first openings are located between the first lattice band and the second lattice band. At least one of the lattice bands may include a yarn having a tenacity of at least 5 g/d, and/or the first and second lattice bands may be formed from separate yarns. |
US11408100B2 |
Terry fabric with faux dobby and methods of making terry fabric with faux dobby
Described is a woven terry fabric article that includes a body having a first end and a second end opposite one another, and a first side edge and a second side edge opposite one another and generally perpendicular to the first and second opposite ends. The article further includes a first terry zone having a pile with a first pile height, a second terry zone having a pile with a second pile height, and a first faux dobby zone intermediate to the first and second terry zones. The first faux dobby zone has a pile with one or more pile heights that are visibly distinct from the pile heights of the first and second terry zones. In embodiments, the one or more pile heights in the faux dobby zone are less than the pile height of the adjacent zones, such as 50% less, 40% less, or 35% less. |
US11408092B2 |
Method for heat-treating silicon single crystal wafer
A method for heat-treating a silicon single crystal wafer to control a BMD density thereof to achieve a predetermined BMD density by performing an RTA heat treatment on a silicon single crystal wafer composed of an Nv region in a nitriding atmosphere, and then performing a second heat treatment, the method including: formulating a relational equation for a relation between BMD density and RTA temperature in advance; and determining an RTA temperature for achieving the predetermined BMD density according to the relational equation. Consequently, a method for heat-treating a silicon single crystal wafer for manufacturing an annealed wafer or an epitaxial wafer each having defect-free surface and a predetermined BMD density in a bulk portion thereof. |
US11408089B2 |
Devices and methods for growing crystals
The present disclosure provides a device for preparing a crystal and a method for growing a crystal. The device may include a growth chamber configured to execute a crystal growth; and a temperature control system configured to heat the growth chamber to cause that a radial temperature difference in the growth chamber does not exceed a first preset range of an average temperature in the growth chamber during the crystal growth. The method may include placing a seed crystal and a source material in a growth chamber to grow a crystal; and controlling a heating component based on information of a temperature sensing component, to cause that a radial temperature difference in the growth chamber does not exceed a first preset range of an average temperature in the growth chamber during a crystal growth. |
US11408086B2 |
Method for creating multiple electrical current pathways on a work piece
A method for plating a work piece. An electroless layer of material is applied to the work piece using an electroless plating process. The method includes creating a barrier in electrical conductivity in the work piece to divide the work piece into a first segment and a second segment which are substantially electrically insulated from one another, prior to electroplating the work piece. A plurality of methods are disclosed for dividing the work piece into the first and second segments. |
US11408084B2 |
Thin film electrode containing nanostructured cobalt oxide for water splitting
A thin film electrode involving a nanostructured catalytic material deposited onto a surface of a conducting substrate and method of making is described. The nanostructured catalytic material contains cobalt oxide nanoflowers having a central core and nanopetals extending from the central core. The method of making the thin film electrode involves contacting the conducting substrate with an aerosol containing a cobalt complex and a solvent. A method of using the thin film electrode in an electrochemical cell for water splitting is also provided. |
US11408083B2 |
Filter press device for electrodeposition of metal from solutions, which is made up of separating elements conformed by ion exchange membranes forming a plurality of anolyte and catholyte chambers, wherein the electrodes are connected in series with automatic detachment of the metal product
A filter press device for electrolytic production of metal for electrodeposition of metal from solutions, constructed from a plurality of cells connected electrically and hydraulically in series. Each has alternating frames and ion-exchange membranes to form alternating anode and cathode compartments, allowing the free path of liquid. Anolyte or catholyte passes through each compartment. The electrolyzed product is discharged from the compartment in the form of metal or a metallic compound. The electrodes are designed with a vertical base plate acting as an anode with the respective anolyte in a cell unit and in the other, acting as a cathode with the respective catholyte in the adjacent cell unit. Completed the production cycle, the device is stopped, the cell is opened, allowing the metal deposition electrodes, cathodes, can be removed and replaced to start a new productive cycle or remain in place with automatic detachment of metal product. |
US11408082B2 |
Electrochemical compression system
An electrochemical system includes an electrochemical compressor through which a working fluid that includes a component that primarily acts as an electrochemically-active component flows; a sealed vessel in which the electrochemical compressor is housed; an inlet conduit for passing working fluid into the vessel; and an outlet conduit for passing fluid out of the vessel. The working fluid that leaks from the electrochemical compressor is contained within the vessel. |
US11408079B2 |
Corrosion inhibitor composition and methods of inhibiting corrosion during acid pickling
A corrosion inhibitor composition, which includes i) an aqueous alcohol base fluid, ii) a mixture of at least three polysaccharides selected from carboxymethyl cellulose, gum arabic, pectin, a salt of alginic acid, chitosan, dextran, hydroxyethyl cellulose, and soluble starch, with each polysaccharide that is present in the mixture being present in an amount of 0.05 to 0.5 wt. %, based on a total weight of the corrosion inhibitor composition, iii) silver nanoparticles, and iv) a pineapple leaves extract. A method of inhibiting corrosion of metal during acid cleaning/pickling whereby the metal is treated with an acidic treatment fluid containing an acid and the corrosion inhibitor composition. |
US11408078B2 |
Method for the anti-corrosion and cleaning pretreatment of metal components
The invention relates to a multiple-step method for the corrosion-protective pretreatment of components, said pretreatment being at least partially produced from a metal material predominantly consisting of at least one of the elements iron zinc and/or aluminium, according to which the components are first brought into contact with an acid aqueous composition (A) containing water-soluble compounds of the elements Zr and/or Ti and then with an acid aqueous composition (B) containing phosphate ions and an accelerator. The method is particularly suitable for the pretreatment before an electrocoating. |
US11408073B2 |
Method for growth of atomic layer ribbons and nanoribbons of transition metal dichalcogenides
A method of making an atomic layer nanoribbon that includes forming a double atomic layer ribbon having a first monolayer and a second monolayer on a surface of the first monolayer, wherein the first monolayer and the second monolayer each contains a transition metal dichalcogenide material, oxidizing at least a portion of the first monolayer to provide an oxidized portion, and removing the oxidized portion to provide an atomic layer nanoribbon of the transition metal dichalcogenide material. Also provided are double atomic layer ribbons, double atomic layer nanoribbons, and single atomic layer nanoribbons prepared according to the method. |
US11408070B2 |
Wafer processing apparatus and wafer processing method
A wafer processing apparatus includes a reaction tube extending in a vertical direction, a door plate configured to load a boat into the reaction tube and positioned under the reaction tube to seal the reaction tube, the boat supporting a plurality of wafers thereon, a gas injector extending in the vertical direction along the boat within the reaction tube and including a plurality of ejection holes formed therein, a rotary mechanism configured to rotate the gas injector about its center axis to adjust an angle of the ejection hole toward the wafer, and a lift mechanism configured to move the gas injector upward and downward to adjust a height of the ejection hole on the wafer. |
US11408068B2 |
Deposition of tellurium-containing thin films
Methods for depositing tellurium-containing films on a substrate are described. The substrate is exposed to a tellurium precursor and a reactant to form the tellurium-containing film (e.g., elemental tellurium, tellurium oxide, tellurium carbide, tellurium silicide, germanium telluride, antimony telluride, germanium antimony telluride). The exposures can be sequential or simultaneous. |
US11408064B2 |
Mask structure and FCVA apparatus
Embodiments of the present disclosure provide a mask structure and a filtered cathodic vacuum arc (FCVA) apparatus. The mask structure is configured to prepare protrusions on a carrying surface of an electrostatic chuck and includes a main mask plate and a side mask plate that are made of a conductive metal. The main mask plate is configured to form a patterned film layer corresponding to the protrusions on the carrying surface of the electrostatic chuck. The side mask is configured to cover a side surface of the electrostatic chuck to avoid forming a film layer on the side surface. The mask structure can be electrically conductive. The mask structure may prevent the side surface of the electrostatic chuck from being coated when the protrusions are prepared on the carrying surface of the electrostatic chuck. Thus, the mask structure may be applied to an FCVA process. |
US11408063B2 |
Mask frame assembly and method of manufacturing the same
A method of manufacturing a mask frame assembly includes: welding fixing ends of a long-side support bar on a frame; and fixing a mask having a pattern area to be divided by the long-side support bar, on the frame, wherein the welding of the fixing ends of the long-side support bar on the frame includes forming welds asymmetrically with respect to a longitudinal central axis of the fixing ends. |
US11408062B2 |
System and method for heat treating aluminum alloy castings
A method for heat treating cast aluminum alloy components that includes obtaining a casting formed from an aluminum alloy having a silicon constituent and at least one metal alloying constituent, and heating the casting to a first casting temperature that is below but within 10° C. of a predetermined silicon solution temperature at which the silicon constituent rapidly enters into solid solution. The method also includes increasing the rate of heat input into the casting to raise the temperature of the casting to a second casting temperature that is above but within 10° C. of a predetermined alloying metal solution temperature at which the at least one metal alloying constituent rapidly enters into solid solution, maintaining the casting at the second casting temperature for a period of time that is less than about 20 minutes, and then quenching the casting to a temperature less than or about 250° C. |
US11408060B2 |
High performance solid lubricating titanium amorphous alloy
The present invention relates to an amorphous alloy having low frictional resistance and capable of improving abrasion resistance, a target made of the amorphous alloy, and a compressor comprising a layer of the amorphous alloy as a coating layer. According to the present invention, it is possible to secure high hardness and a low elastic modulus of the coating layer by controlling a microstructure having an amorphous phase as a primary phase by using Ti-based three-component to five-component amorphous alloys. As a result, it is possible to prevent the coating layer from being peeled off from a matrix or destroyed, and thus it is possible to achieve the effect of improving reliability or durability of a mechanical apparatus such as a compressor. |
US11408055B2 |
Copper alloy production method and method for manufacturing foil from copper alloy
The present invention relates to a copper alloy production method and a method for manufacturing foil from a copper alloy, and the copper alloy production method of the present invention includes: a metal oxide preparing process of preparing at least two metals, including copper, each of which is in the form of a metal oxide, a nano powder producing process of pulverizing the metal oxides to produce metal oxide nano powder having a nano size, and an alloy producing process of heat-treating the metal oxide nano powder to produce an alloy, whereby, when a copper alloy is produced, precipitates can be minimized, the characteristics of the alloy can be optimized, and the generation of oxides on the outer wall of a molten metal furnace can be suppressed. |
US11408051B2 |
Method and system for metal recovery from arsenical bearing sulfides ores
There is provided a method for the removal of arsenic from an arsenical bearing sulfides ore, comprising a thermal treatment of arsenical sulfide in the presence of sulfur dioxide, yielding a calcine and a sublimate, the sublimate containing arsenious oxide. The method allows recovering metallic value from an arsenic-bearing metallic sulfides ore, by recovery of the calcine comprising the metallic value of the ore. |
US11408048B2 |
High-strength, hot rolled abrasive wear resistant steel strip
A high strength, hot rolled abrasive wear resistant steel strip with low carbon equivalent values, with a Brinell hardness in the range of 400-465 HBW and a tensile strength in the range of 1180-1500 MPa for strip thicknesses in the range of 3-20 mm, as well as a process for producing such a high strength, hot rolled abrasive wear resistant steel strip. |
US11408047B2 |
Alloyed hot-dip galvanized steel sheet and alloyed hot-dip galvanized steel sheet production method
In one aspect of the present invention, a hot-dip galvannealed steel sheet includes a steel sheet and a hot-dip galvannealed layer on the surface of the steel sheet. The steel sheet has a predetermined composition and has an average oxygen concentration of 0.10 mass % or less in the region of 1 μm from the interface between the steel sheet and the hot-dip galvannealed layer toward the steel sheet. The metal microstructure of the steel sheet at a position of t/4 where t represents the sheet thickness of the hot-dip galvannealed steel sheet includes 50 to 85 area % of martensite, 15 to 50 area % of bainite, and 5 area % or less of ferrite. |
US11408046B2 |
High strength steel sheet
High strength steel sheet having a tensile strength of 800 MPa or more comprising a middle part in sheet thickness and a soft surface layer arranged at one side or both sides of the middle part in sheet thickness, wherein each soft surface layer has a thickness of more than 10 μM and 30% or less of the sheet thickness, the soft surface layer has an average Vickers hardness of more than 0.60 time and 0.90 time or less the average Vickers hardness of the sheet thickness 1/2 position, and the soft surface layer has a nano-hardness standard deviation of 0.8 or less is provided. |
US11408045B2 |
Steel sheet
There is provided a steel sheet including an inner layer and a hard layer formed on one or both surfaces of the inner layer, wherein each content of C and Mn in the hard layer is more than each content of C and Mn in the inner layer, a thickness of the hard layer is 20 μm or more and a total of the thickness of the hard layer is ⅖ or less of the entire sheet thickness, an average micro-Vickers hardness of the hard layer is 400 HV or more and less than 800 HV, an average micro-Vickers hardness of the inner layer is 350 HV or more and is 50 HV or more smaller than a hardness of the hard layer, and a screw dislocation density of the inner layer is 2.0×1013 m/m3 or more. |
US11408035B2 |
Risk stratification method for a patient having a polymorphism
A risk stratification method for a patient in a disease state and specifically patients presenting a tumor, includes determining if the patient is a homozygote or heterozygote and further determining the allelic expression for the patient, CC, T/C, or C/T. For patients having the cytosine methylated, they have a C/T allelic expression and patients without a methylated cytosine have a T/C allelic expression. A patient with a TT allelic expression is classified as a highest risk patient, a patient with a T/C allelic expression is classified as a second highest risk patient, a patient with a C/T allelic expression is classified as a third highest risk patient and a patient with a CC allelic expression is classified as a lowest risk patient. The risk stratification method may further include identification of an abnormal expression or mutation/function of a gene product produced by CTCF binding site 6. |
US11408034B2 |
Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection. |
US11408032B2 |
Tube lens design for improved depth-of-field
Imaging systems and methods comprising imaging a first interior surface and a second interior surface of a flow cell are described. In some embodiments, the imaging systems may comprise: a) an objective lens; b) at least one image sensor; and c) at least one tube lens disposed in an optical path between the objective lens and the at least one image sensor; wherein the at least one tube lens is configured to correct imaging performance such that images of the first interior surface of the flow cell and the second interior surface of the flow cell have substantially the same optical resolution. |
US11408030B2 |
Test for detecting Alzheimer's disease
Provided herein is technology for Alzheimer's disease testing and particularly, but not exclusively, methods, compositions, and related uses for detecting the presence of Alzheimer's disease. |
US11408028B2 |
Nucleic acid hybridization assay
Provided herein is a method and device for performing a homogeneous nucleic acid detection assay. The device can contain a pair of plates where one of the plates comprises (i) surface amplification surface; and (ii) target-specific nucleic acid probes that are immobilized on said amplification surface and that specifically binds to a part of the target nucleic acid; and the second plate comprises a sample contact area comprising a reagent storage site that comprises target-specific nucleic acid detection agents that specifically binds to another part of the target nucleic acid. In some embodiments, the device can be read without a washing unbound label from the surface of the device. |
US11408027B2 |
Method of evaluating quality of miRNA derived from body fluid
A method of evaluating quality of miRNA derived from a body fluid sample includes a measuring step; comparing a measured value(s) of the abundance(s) of the one or more reference miRNAs in a body fluid sample or a representative value thereof to a measured value(s) of the abundance(s) of the one or more reference miRNAs in a standard body fluid sample or a representative value thereof, to obtain a difference(s) or a ratio(s) of the measured value(s) of the abundance(s) of the one or more reference miRNAs or the representative value thereof between the body fluid sample and the standard body fluid sample; and judging the quality of the miRNA derived from the body fluid sample based on the difference(s) or the ratio(s) of the measured value(s) of the abundance(s) of the one or more reference miRNAs or the representative value thereof obtained in the comparing step. |
US11408026B2 |
Methods of predicting susceptibility to infectious disease and related methods of treatment
Disclosed herein are methods for predicting susceptibility to an infection based on the observation of specific mutations in blood cells, as well as methods for treating or reducing susceptibility to an infection in a subject. |
US11408024B2 |
Methods for selectively suppressing non-target sequences
The invention generally relates to negative selection of nucleic acids. The invention provides methods and systems that remove unwanted segments of nucleic acid in a sample so that a target gene or region of interest may be analyzed without interference from the unwanted segments. A sample is obtained that includes single-stranded nucleic acid with one or more unwanted segments. Complementary nucleic acid is added to the single-stranded nucleic acid to create a double-stranded region that includes the unwanted segment. The double-stranded region is then digested, leaving single-stranded nucleic acid that includes the target gene or region of interest. This allows paralogs, pseudogenes, repetitive elements, and other segments of the genome that may be similar to the target gene or region of interest to be removed from the sample. |
US11408023B2 |
Microbial detection devices including adhesive masked nutrients and methods of using the same
Devices for microbial detection of microorganisms are provided including a body member including a substrate having a first major surface and a second major surface. The device further includes a substantially dry, first microbial growth nutrient composition disposed on a portion of the first major surface, a first adhesive composition adhered to the first microbial growth nutrient composition, and a cold-water-soluble first hydrogel-forming composition adhered to the first adhesive composition. The device also includes a cover sheet attached to the body member, where the cover sheet includes a first major surface facing the body member. Devices including a water-proof pouch are also provided. Methods for detecting and enumerating at least one microorganism in a sample are additionally provided, using the devices. |
US11408020B2 |
Methods for in vitro joining and combinatorial assembly of nucleic acid molecules
The present invention relates to methods of joining two or more double-stranded (ds) or single-stranded (ss) DNA molecules of interest in vitro, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule of each pair share a region of sequence identity. The method allows the joining of a large number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. It can be used, e.g., to join synthetically produced sub-fragments of a gene or genome of interest. Kits for performing the method are also disclosed. The methods of joining DNA molecules may be used to generate combinatorial libraries useful to generate, for example, optimal protein expression through codon optimization, gene optimization, and pathway optimization. |
US11408018B2 |
Fructose-C4-epimerase and preparation method for producing tagatose using the same
The present disclosure relates to a composition for producing tagatose comprising a protein having fructose-4-epimerase activity and a method for producing tagatose using the same. |
US11408012B2 |
Nucleic acid-guided nucleases
Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered non-naturally occurring nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Targetable nuclease systems can be used to edit genetic targets, including recursive genetic engineering and trackable genetic engineering methods. |
US11408010B2 |
Mutant-type flowering-inducing gene, transformed plant having the mutant-type flowering-inducing gene, and flowering regulation method using the mutant-type flowering-inducing gene
A mutant-type flowering-inducing gene encoding a protein comprising an amino acid sequence in which tyrosine corresponding to the tyrosine at position 85 in the amino acid sequence of SEQ ID NO: 2 is substituted by a different amino acid, whereby flowering time is accelerated more slowly than conventionally known flowering-inducing genes, is provided. |
US11408006B2 |
Method for preparing DNA unit composition, and method for creating concatenated DNA
Provided are: a method for preparing a DNA unit composition in which the mol number of a plurality of DNA units is more uniform, and a method for creating concatenated DNA. The method for preparing a DNA unit composition has: a step for preparing solutions which contain a plurality of DNA units to which an added sequence is linked, and preparing a solution for each type of DNA unit and a step for, after preparing each of the solutions, measuring the concentration of the DNA unit in each of the solutions in a state where the added sequence is linked to the DNA unit, and on the basis of the results thereof, fractionating each of the solutions and making the mol number of the DNA unit in each of the solutions closer to being identical to one another. |
US11408005B2 |
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
Provided herein is a system for inducible expression of a chimeric antigen receptor in cells, such as mammalian cells. The system comprises: a) a first nucleic acid comprising a first promoter inducible by a drug, wherein the first nucleic acid is operably linked to a first polynucleotide that encodes a chimeric antigen receptor, which comprises a ligand binding domain that is specific for a ligand selected from the group consisting of a tumor specific molecule, a viral specific molecule, and any other selected molecule expressed on a target cell population, wherein the ligand elicits recognition, modulation, inhibition, and/or elimination by a lymphocyte, a second polynucleotide, which encodes a spacer or an optimized polypeptide spacer, a third polynucleotide, which encodes a transmembrane domain and a fourth polynucleotide, which encodes an intracellular signaling domain and b) a second nucleic acid comprising a second promoter that is operably linked to a nucleic acid encoding a transcriptional activator for the first promoter inducible by drug, wherein the system is inducible by an amount of the drug that is less than a comparable system utilizing a wild type HEA3 chimeric transcription factor, or the system has an enhanced transcriptional expression at a given concentration of the drug compared to a wild type HEA3. Methods of making such cells and methods of treatment using these cells are also provided. |
US11408004B2 |
Treatment of Sirtuin (SIRT) related diseases by inhibition of natural antisense transcript to a Sirtuin (SIRT)
The present invention relates to antisense oligonucleotide that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s. |
US11407995B1 |
RNA-guided nucleases and DNA binding proteins
Compositions and methods related to Cas proteins, nucleic acids encoding the Cas proteins, and modified host cells comprising the Cas proteins and/or encoding nucleic acids are disclosed. Cas proteins are useful in a variety of applications. Cas proteins bind guide RNAs that in turn provide functional specificity to the Cas proteins, nucleic acids encoding the Cas guide RNAs, and modified host cells comprising the Cas guide RNAs and/or encoding nucleic acids. The Cas polypeptides and corresponding guide RNAs can be used in a variety of applications. |
US11407994B2 |
Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells via viral delivery
This invention relates to compositions of matter, methods, modules and instruments for automated mammalian cell growth and mammalian cell transduction followed by nucleic acid-guided nuclease editing in live mammalian cells. The present compositions and methods entail viral delivery of an editing cassette to live mammalian cells such that the editing cassettes edit the cells and the edited cells continue to grow, preferably using a fully-automated end-to-end instrument to process the cells without human intervention to enhance cell processing uniformity and to maintain the integrity of the cell culture. |
US11407993B2 |
Method for the synthesis of DNA conjugates by micellar catalysis
A method for the synthesis of a chimeric conjugate molecule by micellar catalysis that may form part of DNA-encoded compound libraries. A DNA-coupled organic starter molecule may be reacted with another organic compound, using a catalyst located within a micelle, to form a conjugate of an organic candidate compound coupled to a DNA identifier tag. |
US11407992B2 |
Methods of determining a surgical margin and methods of use thereof
Provided herein are methods of determining a surgical margin and the site and size of a tissue to be resected from a subject, and methods of use thereof. |
US11407989B2 |
Protease variants and polynucleotides encoding same
The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. |
US11407988B2 |
Composition and uses thereof
The present invention relates to a composition for degrading prion material comprising a Thermitase. Such compositions may be formed in solution and are particularly suited to degrading prion material on medical equipment or in the environment due to the Thermitases mild pH range and activity at relatively low temperatures. The present invention also relates to novel proteases, methods for prion degradation, decontamination or disinfection and a kit of parts. |
US11407986B2 |
Enzyme variants and polynucleotides encoding same
The present invention relates to polypeptide having alpha-amylase activity. The present invention also relates to polynucleotides encoding the polypeptides; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the polypeptides. |
US11407983B2 |
Nucleic acid molecules comprising a variant RpoC coding sequence
A nucleic acid molecule comprising a variant rpoC coding sequence is disclosed. The variant rpoC coding sequence encodes a variant RpoC which regulates copy number of a plasmid. Also disclosed are a recombinant microorganism comprising the nucleic acid molecule, a method for regulating copy number of a subject vector in the recombinant microorganism, and a method for making a target product by use of the recombinant microorganism. |
US11407982B2 |
Transaminase mutant and use thereof
Disclosed are transaminase mutants and use thereof. The amino acid sequence of the transaminase mutant is obtained by the mutation of the amino acid sequence as shown in SEQ ID NO: 1, and the mutation at least comprises one of the following mutation sites: the 19-th site, the 41-th site, the 43-th site, the 72-th site, the 76-th site, the 92-th site, the 107-th site, the 125-th site, the 132-th site, the 226-th site, the 292-th site, the 295-th site, the 308-th site, and the 332-th site; and the 19-th site is mutated into a serine, the 41-th site is mutated into a serine, the 43-th site is mutated into an asparagine, a glycine in the 72-th site is mutated into a leucine, etc.; or the amino acid sequence of the transaminase mutant has the mutation sites in the mutanted amino acid sequence, and has more than 80% homology to the mutanted amino acid sequence. |
US11407981B2 |
Methods for continuously inactivating a virus during manufacture of a protein
Methods for continuously inactivating a virus during manufacture of a protein are provided. Steps include (1) combining, at a single predetermined volumetric ratio, a composition including the protein, and a composition including a virus-inactivation reagent, to obtain a treatment composition having a predetermined property for inactivation of a virus; (2) transferring the treatment composition to a treatment vessel; (3) incubating the treatment composition in the treatment vessel at predetermined conditions; and (4) subjecting the treatment composition to a post-treatment processing operation. The single predetermined volumetric ratio has been selected to ensure that the predetermined property of the treatment composition is maintained across a range of concentrations predicted for the protein in the composition including the protein. Steps (1) to (3) are carried out (a) continuously and (b) without feedback control being exerted by either adjustment of the volumetric ratio or diversion of the treatment composition. |
US11407980B2 |
Cell culture medium for culturing organoid, culture method, and organoid
A cell culture medium for culturing organoid containing at least two types of components selected from the group consisting of insulin-like growth factor 1 (IGF1), fibroblast growth factor 2 (FGF2) and epiregulin (EREG), and at least one type of component among the following components i) to iii): i) Wnt agonist, ii) bone morphogenetic protein (BMP) inhibitor, and iii) transforming growth factor-β (TGF-β) inhibitor. |
US11407977B2 |
Tissue scaffolds for electrically excitable cells
Inventive concepts relate generally to nanofibrous scaffolds useful for electrophysiological assays. Scaffolds include polymeric nanofibrous components and electrically excitable cells immobilized at a distinct cell seeding domains on the scaffold. Methods and kits including the scaffolds are also described. |
US11407976B2 |
Genetically modified microorganisms having improved tolerance towards L-serine
The present invention generally relates to the microbiological industry, and specifically to the production of L-serine or L-serine derivatives using genetically modified bacteria. The present invention provides genetically modified microorganisms, such as bacteria, wherein the expression of genes encoding for enzymes involved in the degradation of L-serine is attenuated, such as by inactivation, which makes them particularly suitable for the production of L-serine at higher yield. The present invention also provides means by which the microorganism, and more particularly a bacterium, can be made tolerant towards higher concentrations of serine. The present invention also provides methods for the production of L-serine or L-serine derivative using such genetically modified microorganisms. |
US11407973B2 |
Methods for culturing filamentous fungi in fermentation media
Methods for culturing filamentous fungi, in which the filamentous fungi are grown in a colloid of air and a fermentation medium, are provided. The methods result in more rapid and prolific growth of the filamentous fungus than has been achieved by previous methods. Biomats produced by the methods and air-medium colloids for use in the methods are also provided. |
US11407972B1 |
Fungal-derived formulations and associated methods
Methods for stimulating in-vitro Paecilomyces hepiali or Hirsutella sinensis growth, and nutritional supplement formulations containing such fungal strains are disclosed and described. In some embodiments, such a method may include providing a an effective amount of a P. hepiali fungus strain for use as a stimulating agent on a culture medium for which H. sinensis is grown and regulating the temperature to induce and maintain the growth of the H. sinensis fungus. Alternatively, a P. hepiali fungus may be grown in a similar manner using H. sinensis as the stimulating agent. In some aspects, the growth of one fungus may be sequentially switched with the other in order to improve fungi potency. |
US11407969B2 |
System and method for generating biological tissue
The present invention relates in part to devices, systems, and methods for the production and characterization of engineered tissue constructs. The devices and methods generate decellularized tissue constructs that can be recellularized using donor cells for high-throughput studies of organ physiology, and/or organ pathology. The devices and methods can be used with the systems to mechanically and electrically stimulate the engineered tissue constructs under culture or physiological conditions to detect and assess the presence and degree of any organ pathologies. |
US11407968B2 |
Systems, methods, and apparatuses for media rehydration
The present set of embodiments relate to a system, method, and apparatus for hydrating and mixing a liquid medium from a dry medium. Such systems, methods, and apparatuses can be used in the biotech industry because they can be used to provide prepackaged dry media in a format that can be quickly rehydrated free of issues with operator error found in more conventional media rehydration systems using mixing tanks and reactors. |
US11407959B2 |
Driveline fluids comprising API group II base oil
Described herein is a process, comprising: a) selecting an API Group II base stock with selected viscosity index and pour point; b) blending a base oil with the base stock, and c) adding to the base oil: i) a liquid ethylene propylene copolymer viscosity modifier that reduces a traction coefficient, and ii) an additive package, to make a driveline fluid that has a defined viscosity index and excellent shear stability. Also provided is a driveline fluid composition having the high viscosity index and excellent shear stability, comprising: a) a base oil comprising from 50 wt % to 100 wt % API Group II base stock; b) a liquid ethylene propylene copolymer viscosity modifier that reduces a traction coefficient; and c) an additive package. Further provided is a method for lubricating an axle or manual transmission by supplying the driveline fluid composition. |
US11407957B2 |
Wear resistant polymer composition having improved surface appearance
A tribologically modified polyoxymethylene polymer composition is disclosed. The polyoxymethylene polymer composition is comprised of a polyoxymethylene polymer in combination with a tribological modifier system. The tribological modifier system may include the combination of a fluoropolymer with a high density polyethylene, such as an oxidized high density polyethylene. The particular formulation provides a synergistic blend of properties. For instance, the polymer composition not only has an excellent surface appearance when molded into articles but has excellent low friction characteristics when tested against aluminum. |
US11407955B2 |
Method of agglomerating fine particles using a concentrated water in oil emulsion
A method of agglomerating fine particles such as ultrafine coal in a beneficiation process, uses a water in oil emulsion to significantly reduce the amount of oil needed compared with known oil in water emulsions. A solution of oil and emulsifying agent is provided to which water is progressively added forming a concentrated water in oil emulsion with stabilized water drops (1) packed inside the oil solution phase (2). Fine particles in a slurry are then added, causing the fine particles to collide and stick to the emulsion particles. An optional form of the invention coats tiny portions of the emulsion in a thin film of low viscosity oil (5) to achieve a higher level of selectivity. |
US11407954B2 |
Processing of low rank coal
A method of preparing a fuel composition includes placing coal having a heat content between about 3,000 BTU/lb and about 9,000 BTU/lb and a moisture content between about 20 wt % and about 60 wt % in a vessel. The coal is exposed to heat and a pressure less than atmospheric pressure within the vessel, thereby reducing the coal, such that an average primary particle size of the coal is less than 1 millimeter. A binder is introduced to the vessel, such that the coal combines with the binder to yield a mixture. The mixture is shaped to yield a fuel composition. |
US11407951B2 |
Aviation gasolines containing mesitylene and isopentane
Describe are preferred formulations for Avgas meeting the requirements for use in aircraft, including requirements established under ASTM standards and by the Federal Aviation Administration. In one embodiment, a binary mixture of 1,3,5-trimethyl benzene (mesitylene) and isopentane is used to provide a MON of at least 100, and more preferably at least 102. In other embodiments, the amounts of mesitylene and/or isopentane may be changed, and other fuel components are included. These various Avgas formulations are thereby adjusted to meet a variety of requirements as to octane rating, RVP, cold start, and other fuel characteristics. |
US11407950B2 |
Process for mixing dilution steam with liquid hydrocarbons before steam cracking
A process for steam cracking a whole crude including a volatilization step performed to maintain a relatively large hydrocarbon droplet size. The process may include contacting a whole crude with steam to volatilize a portion of the hydrocarbons, wherein the contacting of the hydrocarbon feedstock and steam is conducted at an initial relative velocity of less than 30 m/s, for example. The resulting vapor phase, including volatilized hydrocarbons and steam may then be separated from a liquid phase comprising unvaporized hydrocarbons. The hydrocarbons in the vapor phase may then be forwarded to a steam pyrolysis reactor for steam cracking of the hydrocarbons in the vapor phase. |
US11407944B2 |
Light-absorbing anisotropic film, optical laminate, and image display device
An object of the present invention is to provide a light-absorbing anisotropic film having an excellent degree of alignment of a dichroic azo coloring agent; an optical laminate including the same; and an image display device using the same. The light-absorbing anisotropic film according to an embodiment of the present invention is a light-absorbing anisotropic film which is formed of a liquid crystal composition containing a dichroic azo coloring agent compound, a liquid crystalline compound, and a compound represented by Formula (1) and has a front transmittance of 60% or less, and in which a content mass ratio of the dichroic azo coloring agent compound to the liquid crystalline compound is 5% to 35% by mass. |
US11407942B2 |
Garnet silicate, garnet silicate phosphor, and wavelength converter and light emitting device which use the garnet silicate phosphor
Garnet silicate is garnet silicate containing, as a main component, silicate represented by a general formula: Lu2CaMg2(SiO4)3. The garnet silicate includes primary particles having a particle shape derived from a crystal structure of garnet. Moreover, the garnet silicate further contains alkaline metal including at least lithium, in which a content of the alkaline metal is less than 2000 ppm. The garnet silicate phosphor includes garnet silicate and ions which are included in the garnet silicate and function as a light emission center. The wavelength converter includes the garnet silicate phosphor. A light emitting device includes the garnet silicate phosphor or the wavelength converter. |
US11407938B2 |
Structure, agglomerate, conversion element and method of producing a structure
A structure may include a quantum structure and a barrier layer that may coat the quantum structure. The barrier layer may include aluminum and at least one material that is X1, X2, Si, O, or combinations thereof where X1 and X2 are monovalent positively charged elements and/or divalent positively charged elements. In addition, an agglomerate, a conversion element, and a method of producing a structure are disclosed. |
US11407937B2 |
In-situ cross-linking of emulsified quantum dot-containing domains within a carrier resin
The present invention provides quantum dot compositions and methods of producing quantum dot compositions. The quantum dot compositions comprise a population of quantum dots, an aminosilicone polymer, an epoxy-functional silicone, and an organic resin. The present invention also provides quantum dot films comprising a quantum dot layer and methods of making quantum dot films. |
US11407936B2 |
Composition for forming a quantum dot layer, quantum dot film, backlight unit, and liquid crystal display
The present invention relates to a composition for forming a quantum dot layer comprising: at least one active energy ray-curable compound (A) having an ethylenically unsaturated double bond, at least one thiol compound (B) having at least two mercapto groups in one molecule, a photo-initiator (C); quantum particles (D), and scattering particles (E), wherein the composition contains 0.20-0.80 equivalents of the compound (B) per one equivalent of the compound (A), and the W value of the compound (A) calculated by Math formula 1 is 3.0 or more, and the present invention also relates to a quantum dot film, a backlight unit, and a liquid crystal display. |
US11407930B2 |
Compositions and methods for enhancement of production of liquid and gaseous hydrocarbons
A well treatment composition designed for the simultaneous enhancement of the production of both liquid and gaseous hydrocarbons from the same reservoir on a non-selective basis. The well treatment composition includes a first surfactant and a second surfactant, wherein the second surfactant is selected from the group consisting of ethylenediaminealkoxylate, diethylenetriaminealkoxylate, ethoxylated alkylene amines, ethoxylated alkyl amines, propoxylated alkylene amines, propoxylated alkyl amines, ethoxylated-propoxylated alkylene amines and ethoxylated-propoxylated alkyl amines. The well treatment composition also includes a first solvent, a second solvent and water. Methods for using the well treatment composition include the steps of emplacing the well treatment composition into wells having high and low gas-to-oil ratios. |
US11407928B2 |
Organophilic clay based drilling fluids containing Gemini surfactant and polyacrylamide
A drilling fluid formulation which includes an aqueous phase, and additives including an organophilic clay, a gemini surfactant, and a polyacrylamide. The organophilic clay contains an ion-exchange reaction product of a clay material (e.g. smectite) and quaternary ammonium cations. The polyacrylamide contains reacted units of an acrylamide monomer, an acrylate monomer, and a hydrophobicity modifying monomer. Rheology properties of the drilling fluid including gel strength, yield stress, and storage modulus are specified. The additives present in the drilling fluid synergistically boost its shale swelling inhibition capability. |
US11407927B2 |
Additives for oil and gas drilling and production
A quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of synthesizing a quaternary amine composition comprising the steps of reacting an alkoxylated dimer diamine with a methyl halogen, where the methyl halogen is selected from the group consisting of methyl chloride, methyl iodine, and combinations of the same; and allowing the reaction to proceed to produce the quaternary amine composition, the quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of treating a well comprising the steps of introducing an additive-containing well fluid to a well, where the additive-containing well fluid comprises a quaternary amine composition and a well fluid, allowing the additive-containing well fluid to interact with the well, and treating the well with the additive-containing fluid. |
US11407926B2 |
Water-based adhesives
An adhesive includes a polymeric latex, a penetrant selected from the group consisting of: terpenes, polylimonene, limonene, carvone, α-pinene, citral, dipentene, 1,8-cineole, eucalyptol, citronellol, geraniol, citronellene, terpinen-4-ol, borneol, camphor, guayule resin, and combinations thereof; and a reinforcing filler. The adhesive has a solids content of 35-65% and a pH of 9 to 12. Articles of manufacture, such as tires and air springs incorporate the adhesive to join rubber interfaces. A method of making the adhesive is also is provided. |
US11407923B2 |
Polishing compositions for reduced defectivity and methods of using the same
Chemical mechanical polishing compositions include an abrasive, an additive, and water. The polishing compositions have a value of less than 800,000 for the relation: large particle counts/weight percent abrasive, when measured using a 0.2 μm bin size. |
US11407922B2 |
Si-containing film forming compositions and methods of making and using the same
Si-containing film forming compositions are disclosed comprising a precursor having the formula [—NR—R4R5Si—(CH2)t—SiR2R3—]n wherein n=2 to 400; R, R2, R3, R4, and R5 are independently H, a hydrocarbon group, or an alkylamino group, and provided that at least one of R2, R3, R4, and R5 is H; and R is independently H, a hydrocarbon group, or a silyl group. Exemplary pre-cursors include, but are not limited to, [—NH—SiH2—CH2—SiH2—]n, and [—N(SiH2—CH2—SiH3)—SiH2—CH2—SiH2—]n. |
US11407921B2 |
Reaction products of catechol compounds and functionalized co-reactant compounds for metal pretreatment applications
An aqueous, acidic, anti-corrosion conversion coating composition (in particular, an aqueous, acidic Group IV metal-containing anti-corrosion conversion coating composition) for metal substrates comprising as an additive a catechol compound and/or the reaction products of at least one catechol compound and at least one co-reactant compound having one or more functional groups reactive with the at least one catechol compound, desirably the reaction product of a catechol and an polyamine (e.g., a polyethyleneimine), that enhances the anti-corrosion effects of the conversion coating composition; methods of making and applying the conversion coating compositions and coated metal substrates. The catechol-containing conversion coating composition can be applied to metal substrate surfaces at temperatures as low as below 40° C. and with exposure times of 5 minutes or less. The catechol compound or reaction product thereof can become incorporated into the conversion coating formed on the metal substrate. |
US11407919B2 |
Curable film-forming compositions demonstrating increased wet-edge time
The present invention is directed to a curable film-forming composition comprising: (a) a curing agent comprising reactive isocyanate functional groups; (b) a film-forming compound comprising functional groups reactive with the reactive isocyanate functional groups in (a); (c) a photo-latent catalyst; (d) a beta-diketone having a flash point higher than 60 C (140 F); and (e) a beta-diketone having a flash point lower than or equal to 60 C (140 F). The invention is further directed to methods of controlling the rate of cure and increasing the wet-edge time of a curable film-forming composition comprising an isocyanate functional curing agent, by adding to the curable film-forming composition a catalyst component comprising: (i) a photo-latent catalyst; (ii) a beta-diketone having a flash point higher than 60 C (140 F); and (iii) a beta-diketone having a flash point lower than or equal to 60 C (140 F). |
US11407916B2 |
Formulations containing a mixture of at least two different solvents
The present invention relates to formulations for the preparation of organic electronic devices which comprise at least one organic functional material and a mixture of at least two different solvents wherein a first organic solvent exhibits a lower boiling point than a second organic solvent and said first organic solvent exhibits a higher viscosity than said second organic solvent. |
US11407907B2 |
Formulation of an organic functional material
The present invention relates to a formulation containing at least one organic functional material and at least two different solvents, a first organic solvent A and a second organic solvent B, wherein the first organic solvent A comprises a group, which is capable of receiving or giving a hydrogen bonding, and wherein the second organic solvent B has a boiling point in the range from 150 to 350° C. and the solubility of the at least one organic functional material in the second organic solvent is ≥5 g/l. |
US11407906B2 |
Powder composition of polyarylene ether ketone ketones allowing an excellent castability/coalescence balance suitable for laser sintering
A method for producing a surface coated with a coating having an improved coalescence, the method including: providing a composition comprising from 99.6% to 99.99% by weight of at least one powder of at least one polyarylene ether ketone and 0.01 to 0.4% by weight of a hydrophilic flow agent, the hydrophilic flow agent being hydrophilic silica; depositing the composition onto a surface forming a coated surface; and baking the coated surface to form a film on the surface. |
US11407900B2 |
Pearlescent pigment for security purposes including organic or inorganic fluorescent material
A pearlescent pigment for security purposes according to an embodiment of the present invention includes a single or a plurality of coating layers containing a metal oxide and an organic or inorganic fluorescent material. Since the pearlescent pigment for security purposes according to the present disclosure includes a fluorescent layer containing the organic or inorganic fluorescent material, it can be used as a pigment for security purposes due to its optical characteristics and can also provide effects such as magnetism, high color intensity, multiple colors, etc. Also, since the pearlescent pigment for security purposes has aesthetic benefit and security characteristic at the same time, it is economical, easy to use and applicable in various industries. |
US11407898B2 |
Curable fluorinated silsequioxane compositions
Curable silsesquioxane compositions, include three dimension networks of Formula I, Formula II, or a combination of Formula I and Formula II, where the oxygen atom at the * is bonded to another Si atom, R is a fluorinated organic group, R2 is an ethylenically unsaturated organic group, n+m is greater than 3, and the —OH groups are present in an amount of at least 15 wt-% of the network. The curable composition may also include a silanol-terminated fluorinated polysiloxane fluid. The curable composition is a coatable composition that is solvent free and wets glass. The curable composition, when cured, has a refractive index of 1.40 or lower. |
US11407891B2 |
Epoxy acrylic hybrid resins
An aqueous dispersion comprising at least one fatty acid-modified epoxy amine adduct wherein the fatty acid has an iodine number of lower than 30 and at least one polymer obtained from the polymerization of one or more ethylenically unsaturated monomers and their use for forming coatings or binder agents, especially for decorative and protective coating applications on various substrates. |
US11407890B2 |
Dual cure additive manufacturing resins for production of flame retardant objects
The present invention concerns methods of forming a three-dimensional object, and polymerizable liquids such as dual cure resins useful for making a three-dimensional object by stereolithography, such as by continuous liquid interface production (CLIP), wherein the three-dimensional object is flame retardant. |
US11407888B2 |
Ethylene-vinyl alcohol copolymer composition, pellets, and multilayer structure
An ethylene-vinyl alcohol copolymer composition contains: (A) an ethylene-vinyl alcohol copolymer; (B) a styrene derivative; and (C) an iron compound; wherein the iron compound (C) is present in an amount of 0.01 to 5 ppm on a metal basis based on the weight of the ethylene-vinyl alcohol copolymer composition. The ethylene-vinyl alcohol copolymer composition has ultraviolet absorbability even without a known ultraviolet-absorbing agent blended therein, and is excellent in heat stability and reduced susceptibility to coloration. |
US11407881B2 |
Process for the preparation of precipitated silicas, precipitated silicas and their uses, in particular for the reinforcement of polymers
The invention relates to a process for the preparation of a novel precipitated silica, wherein: a silicate is reacted with an acidifying agent, so as to obtain a silica suspension; said silica suspension is filtered, so as to obtain a filter cake; said filter cake is subjected to a liquefaction operation, optionally in the presence of an aluminium compound; wherein at least one polycarboxylic acid is added to the filter cake, during or after the liquefaction operation. It also relates to a novel precipitated silica and to its uses. |
US11407875B2 |
Process for producing foam beads using a modified ethylene-based polymer
The present disclosure provides a process. The process includes (i) forming a composition containing a peroxide-modified ethylene-based polymer selected from the group consisting of a peroxide-modified ethylene/a-olefin multi-block copolymer, a peroxide-modified low density polyethylene, and combinations thereof; (ii) contacting the composition with a blowing agent to form a foam composition; and (iii) forming foam beads comprising the foam composition. The present disclosure also provides a foam bead produced by said process. |
US11407872B2 |
Foam compositions comprising polylactic acid polymer, polyvinyl acetate polymer and plasticizer, articles, and methods of making and using same
Foam compositions are provided including a polylactic acid polymer; second (e.g., polyvinyl acetate) polymer having a glass transition temperature (Tg) of at least 25° C.; and plasticizer. Also described are articles comprising the foam compositions, such as a sheet or hearing protection article. Methods of making and using the foam compositions are further described herein. |
US11407871B2 |
Method for modifying polymer, method for producing modified polymer using the same, and modified polymer
The present invention provides a new method by which polymers can be modified. The present invention provides a method for modifying a polymer including the step of: irradiating a reaction system containing a polymer with light to react the reaction system in a presence of a compound radical, wherein the compound radical is a radical containing one element selected from the group consisting of Group 15 elements and Group 16 elements, and a Group 17 element. |
US11407870B2 |
Hard coat laminated film
Embodiments relate to a hard coat laminated film having a first hard coat, a second hard coat, and a transparent resin film layer, where: the first hard coat is formed from paint which contains predetermined amounts of (A) a multifunctional (meth)acrylate, (B) a water repellent, and (C) a silane coupling agent, and which does not contain inorganic particles; and the second hard coat is formed from paint containing predetermined amounts of (D) a polymerizable compound and (E) inorganic fine particles having an average particle size of 1-300 nm. The (D) polymerizable compound contains: (d1) a multifunctional (meth)acrylate having three or more (meth)acryloyl groups in one molecule; (d2) a compound having two or more secondary thiol groups in one molecule; and optionally, (d3) at least one (meth)acrylate selected from the group consisting of a (meth)acrylate having two (meth)acryloyl groups in one molecule, a (meth)acrylate having one (meth)acryloyl group in one molecule, and a urethane(meth)acrylate. |
US11407864B2 |
Fiber-reinforced resin, process for producing same, and molded article
(A) A reinforcing fiber, (B) a resin particle, and (C) a matrix resin are combined to prepare a resin composition which improves a reinforcing effect by the reinforcing fiber. The reinforcing fiber (A) contains a carbon fiber. The resin particle (B) contains a semicrystalline thermoplastic resin, the semicrystalline thermoplastic resin in the resin particle (B) has an exothermic peak in a temperature range between a glass transition temperature of the semicrystalline thermoplastic resin and a melting point of the semicrystalline thermoplastic resin, the peak being determined by heating the resin particle (B) at a rate of 10° C./min. by differential scanning calorimetry (DSC), and the resin particle (B) has an average particle size of 3 to 40 μm. The semicrystalline thermoplastic resin may be a polyamide resin having a melting point of not lower than 150° C. (particularly, a polyamide resin having an alicyclic structure and a glass transition temperature of not lower than 100° C., or a polyamide resin having a γ-type crystal structure or a degree of crystallinity of not more than 50%). The matrix resin (C) may be a thermosetting resin. |
US11407862B2 |
Silicone and a method for preparing the same
One of the purposes of the present invention is to provide a silicone which has polymerizable groups at the both terminals and a hydrophilic side chain having three or four hydroxyl groups, is colorless and transparent and is well compatible with another monomer, particularly with hydrophilic monomer, and a method for preparing the same. The present inventor has made research to solve the afore-mentioned problems and found that a silicone represented by the formula (1), which has an unbranched or branched alkyl group represented by —CpH2p+1−q(OH) and a hydrophilic side chain containing an ether bond, has no coloration and is well compatible with other hydrophilic monomers. Therefore, the silicone polymerizes with a monomer having high hydrophilicity to give a colorless, transparent and highly hydrophilic copolymer. Further, the present inventors have found that the silicone represented by the formula (1) is obtained by addition reacting an organohydrogenpolysiloxane represented by the formula (4) with a compound represented by the formula (5). |
US11407858B2 |
Polyamide-imide resin film
The present invention relates to a polyamide-imide resin film having a low birefringence index, including: a polyamide-imide block copolymer containing an amide repeating unit to which an isophthaloyl group and an aromatic diamine residue are bonded; an imide repeating unit; and a trivalent functional group containing an aromatic tricarbonyl group. |
US11407857B2 |
Method for producing aqueous polyimide precursor solution composition
A method for producing an aqueous polyimide precursor solution composition includes forming a polyamic acid by the reaction of a tetracarboxylic acid component and a diamine component in an aqueous solvent together with an imidazole in an amount of 1.6 mole or more per mole of the tetracarboxylic acid component of the polyamic acid. |
US11407855B2 |
Ring opening polymerization in an aqueous dispersion
We have developed a ring opening polymerization method in an aqueous dispersion for the formation of latex. By encapsulating a catalyst in micelles dispersed in water, a seeded catalytic polymerization of various monomers in water was successfully performed. An amphiphilic molecule was used to form a micelle with a hydrophobic core in water. The catalyst that was encapsulated within this structure and the formed microcapsules were used as microreactors for the formation of biodegradable elastomers. |
US11407849B2 |
Method for manufacturing graft polymer, graft polymer, and initiator of graft polymer
A method for manufacturing a graft polymer, that ensures more stable progress of a living radical polymerization by using a monomer structural unit containing an iodine initiating group as an initiator, includes performing a living radical polymerization of a compound with a vinyl monomer by an organic catalyst to manufacture the graft polymer. The compound has a recurring unit represented by a formula (1) below in a main chain: where, R1: linking group (linear, branched, or cyclic alkylene group having 1 to 30 carbon atoms that may contain an ether bond, an amide bond, or an ester bond, an aromatic group), R2, R3, R4, R5, R6: an aromatic group, an aliphatic group, a hydrogen atom, an aliphatic group, and n=1 to 5. |
US11407846B2 |
(Meth)acrylate, monomer composition, dental material obtained from composition, and production method thereof
Provided are a monomer which can provide a cured product having both high toughness and rigidity, a monomer composition containing the monomer, the monomer composition used as a dental material monomer composition, a dental material composition containing the monomer composition or the dental material monomer composition, a cured product thereof having excellent mechanical properties, a dental material formed by curing the dental material composition, a method for producing the monomer composition, and a method for producing the dental material. A (meth)acrylate (D) is a reaction product of an amine compound (A) having two or more amino groups, an iso(thio)cyanate compound (B) having two or more iso(thio)cyanato groups, and a hydroxy (meth)acrylate compound (C) having one or more polymerizable groups. |
US11407845B2 |
Residual monomer content controlling method of polymer
A method for controlling a residual monomer content of a polymer, wherein when a hot-air temperature and a hot-air velocity are maintained, the controlling method can predict the content of the residual monomer by controlling a hot-air mass ratio without influence of other external factors. |
US11407844B2 |
Catalyst components for the polymerization of olefins
A solid catalyst component for the polymerization of olefins made from or containing Mg, Ti, Cl and at least an electron donor compound which is the reaction product obtained by bringing into contact a Mg compound and a Ti compound having at least a Ti-halogen bond with an electron donor selected from diphenol derivatives. |
US11407843B2 |
Process for producing nitrile rubbers using ruthenium complex catalysts
The present invention relates to a process for preparing nitrile rubbers having reduced molecular weight by metathesis of a first nitrile rubber in the presence of specific ruthenium complex catalysts that have particular N-heterocyclic carbene ligands. |
US11407837B2 |
GPCR binding proteins and synthesis thereof
Provided herein are methods and compositions relating to G protein-coupled receptor (GPCR) libraries having nucleic acids encoding for a scaffold comprising a GPCR binding domain. Libraries described herein include variegated libraries comprising nucleic acids each encoding for a predetermined variant of at least one predetermined reference nucleic acid sequence. Further described herein are protein libraries generated when the nucleic acid libraries are translated. Further described herein are cell libraries expressing variegated nucleic acid libraries described herein. |
US11407832B2 |
Recombinant protein targeting PD-L1 and VEGF
Disclosed is a recombinant protein containing 1) an anti-PD-L1 antibody heavy chain and an anti-PD-L1 antibody light chain, which two are linked by a disulfide bond to bind PD-L1, and 2) an extracellular Ig-like domain of a vascular epithelial growth factor receptor (VEGFR), linked via a linker to the N-terminus or C-terminus of the heavy chain or the light chain, wherein the recombinant protein is capable of binding PD-L1, VEGF and Fc receptor simultaneously. Also disclosed are a recombinant antibody containing two recombinant proteins of the disclosure, a polynucleotide encoding the recombinant protein, an expression vector containing the polynucleotide, a method for producing the recombinant protein and a method for treating a disease caused by over expression of VEGF and/or PD-L1 using the recombinant protein. |
US11407829B2 |
LAG3 binding peptides
This disclosure provides peptides which bind to LAG3, such as SAPWEPLHWPEDWWQGTGEW (SEQ ID NO:1), and can be used to block the interaction of LAG 3 with other molecules such as MHC-II, FGL1, and α-synuclein. These peptides can be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, or inhibiting the progression of a synucleinopathy, inhibiting the progression of sepsis, inhibiting the progression of an infectious disease, and enhancing a response to a vaccine. |
US11407826B2 |
Screening method for pain suppressor and pharmaceutical composition for prevention or treatment of pain
The present invention provides a screening method for a pain suppressor, which method comprises using FLRT3 to select a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. In addition, the present invention provides a pharmaceutical composition for prevention or treatment of pain, which pharmaceutical composition comprises, as an active ingredient, a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. |
US11407824B2 |
Nucleic acids encoding antibodies against IL-1 beta
The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions. |
US11407823B2 |
Treatment of cancer with anti-LAP monoclonal antibodies
Described herein are compositions and methods relating to LAP-binding agents, including, for example, anti-LAP antibodies, and to their use in methods of treatment of cancer. LAP-binding agents affected both systemic and intra-tumor immunity and were shown effective to treat a broad spectrum of cancer types. |
US11407822B2 |
Treatment of fibrodysplasia ossificans progressiva
Methods for treating Fibrodysplasia Ossificans Progressiva (FOP) are provided. Such methods involve administering to a subject having FOP an effective regime of an activin receptor type 2A (ACVR2A) and/or an activin receptor type 2B (ACVR2B) antagonist or an activin receptor type 1 (ACVR1) antagonist. Antagonists include fusion proteins of one or more extracellular domains (ECDs) of ACVR2A, ACVR2B and/or ACVR1 and the Fc domain of an immunoglobulin heavy chain, and antibodies against ACVR2A, ACVR2B, ACVR1 or Activin A. |
US11407821B2 |
Anti-C5A antibodies
The present disclosure relates to, inter alia, antibodies, or antigen-binding fragments thereof, that bind to C5a and to use of the antibodies in methods for treating or preventing complement-associated disorders such as, but not limited to, atypical hemolytic uremic syndrome, age-related macular degeneration, rheumatoid arthritis, sepsis, severe burn, antiphospho lipid syndrome, asthma, lupus nephritis, Goodpasture's syndrome, and chronic obstructive pulmonary disease. |
US11407817B2 |
Monoclonal antibodies and cocktails for treatment of Ebola infections
Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus. |
US11407815B2 |
Stabilized fibronectin based scaffold molecules
Provided herein are proteins comprising a fibronectin based scaffold (FBS) domain, e.g., 10Fn3 molecules, that bind specifically to a target, and wherein the FBS domain is linked at its C-terminus to a region consisting of PmXn, wherein P is proline, X is any amino acid and wherein n is 0 or an integer that is at least 1 and m is an integer that is at least 1, and wherein the PmXn moiety provides an enhanced property to the FBS domain, e.g., enhanced stability, relative to the protein that is not linked to the PmXn moiety. |
US11407814B2 |
Multi-functional and multi-valent interleukin-TGF-beta receptor fusion polypeptides
Provided are multi-functional and multi-valent fusion polypeptides comprising an interleukin polypeptide and two or more TGFβ ligand-binding polypeptides. The compositions and methods provided herein are useful in the application of preventing tumorigenesis and treating cancer. |
US11407811B2 |
Fusion protein, preparation method therefor and use thereof
The invention discloses a fusion protein, preparation method thereof and use thereof and belongs to the field of biopharmaceutical technology. The fusion protein according to the present invention has anti-tumor, anti-autoimmune diseases and anti-inflammatory functions, and therapeutic effects on ophthalmic diseases. According to the long-acting, multifunctional fusion protein of the present invention, the EDSM-Y or EDSM-X polypeptide is fused to the antibody immunoglobulin Fc fragment by a flexible linker so as to obtain the fusion proteins I-V, which can improve the efficacy, prolong the half-life and enhance stability, have characteristics of strong effect, low toxicity and the like, and can be used for the prevention and treatment of solid tumors and various types of inflammation and neovascular ophthalmic diseases. The fusion protein is expressed in a prokaryotic cell or a eukaryotic cell by a genetic engineering method, and the expressed fusion protein is obtained by affinity chromatography. |
US11407810B2 |
Peptides and combination of peptides for use in immunotherapy against various tumors
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
US11407807B2 |
Peptides and combination of peptides for use in immunotherapy against various tumors
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
US11407805B2 |
Modified monocytes/macrophage expressing chimeric antigen receptors and uses thereof
The present invention includes methods and compositions for treating cancer, whether a solid tumor or a hematologic malignancy. By expressing a chimeric antigen receptor in a monocyte, macrophage or dendritic cell, the modified cell is recruited to the tumor microenvironment where it acts as a potent immune effector by infiltrating the tumor and killing the target cells. One aspect includes a modified cell and pharmaceutical compositions comprising the modified cell for adoptive cell therapy and treating a disease or condition associated with immunosuppression. |
US11407803B2 |
Compositions and methods of chimeric autoantibody receptor T cells
The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an autoantibody, vectors comprising the same, compositions comprising CAAR vectors packaged in viral particles, and recombinant T cells comprising the CAAR. The invention also includes methods of making a genetically modified T cell expressing a CAAR (CAART) wherein the expressed CAAR comprises a desmoglein extracellular domain. |
US11407799B2 |
Muscle performance improvement compounds comprising C-terminus agrin fragment and an ACTR2B inhibitor
A compound comprising at least two components, a first component being the nLG3 or (h)nLG3 domain from the C-terminus of mouse or human agrin, and at least one second component, selected from proteins or an antagonistic antibody that inhibit ActR2B-induced signaling activity in the presence of myostatin, the components being linked by means of linking entities.Such compounds are effective treatments for neuromuscular diseases and problems. |
US11407798B2 |
Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
US11407789B2 |
Cell-penetrating compstatin analogs and uses thereof
In some aspects, the present invention cell-penetrating compstatin analog and compositions comprising cell-penetrating compstatin analog. In some aspects, the invention further provides methods of using cell-penetrating compstatin analogs treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ, to inhibit production or release of biologically active C3 cleavage products. |
US11407788B2 |
Prostate-specific membrane antigen (PSMA) targeting peptides
Described herein is the discovery of novel PSMA-specific peptides, which were identified through a novel combinatorial biopanning method. One of the novel PSMA-specific peptides discovered, GTIQPYPFSWGY (or GTI) (SEQ ID NO: 2), exhibits high binding affinity and selectivity to PSMA and PSMA-positive prostate cancer cells. It was found that GTI can mediate internalization of the apoptotic KLA peptide to PSMA-positive LNCaP cells and induce cell death. Moreover, a FAM-labeled GTI peptide shows a high and specific tumor uptake in nude mice bearing human prostate cancer xenografts. It was demonstrated that the GTI peptide can be employed as a PSMA-specific ligand for prostate cancer diagnosis and/or for targeted drug delivery to prostate cancer cells. |
US11407787B2 |
Crystal of oxidized glutathione dication salt and production method therefor
The present application discloses a crystal of oxidized glutathione dication salt and a method of producing the same. |
US11407778B2 |
Method and an apparatus for recovering chemicals from an alkaline lignin material
In a method and an apparatus for recovering chemicals from an alkaline lignin material, the alkaline lignin material (3) which comprises NaOH or KOH is precipitated in presence of an acid in a precipitation stage (6) for forming a precipitated lignin (7), the precipitated lignin (7) is supplied to a separation stage (8) in which a purified lignin (9) is recovered and from which at least one fraction (10) which comprises Na or K is supplied to a crystallization stage (11), and the fraction (10) which comprises Na or K is treated by crystallization in the crystallization stage (11) for forming a crystallized compound (12). Further, the invention relates to use of the purified lignin, and lignin and chemical products. |
US11407775B2 |
Compositions and methods for phosphoramidite and oligonucleotide synthesis
The present disclosure, among other things, provides technologies for preparing and purifying phosphoramidites for oligonucleotide synthesis. |
US11407774B2 |
Polycyclic aromatic compound
By providing a novel polycyclic aromatic compound in which a plurality of aromatic rings is linked via a nitrogen atom, a boron atom, or the like, options of a material for an organic EL element are increased. In addition, by using the novel polycyclic aromatic compound as a material for an organic electroluminescent element, an excellent organic EL element is provided. |
US11407772B2 |
Optically-active cyclopentenone derivatives
The present invention provides: industrially desirable and novel optically-active cyclopentenone derivatives; and a novel industrial manufacturing method. The novel optically-active cyclopentenone derivatives and method for manufacturing the same are, respectively: an intermediate for industrially desirable and novel prostaglandin derivatives and the like; and a method for manufacturing the same. It is expected that the present invention will be commercialized and industrialized. |
US11407767B2 |
Heterocyclyl substituted pyrrolopyridines that are inhibitors of the CDK12 kinase
This invention related to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by the CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular, the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein. |
US11407763B2 |
Tryptophan hydroxylase inhibitor and pharmaceutical composition including same
The present invention relates to a novel tryptophan hydroxylase inhibitor and a pharmaceutical composition including same, wherein the novel tryptophan hydroxylase inhibitor has an excellent inhibitory effect on TPH1, and thus can be usefully used for the prevention or treatment of disorders, such as metabolic disorders, cancer, digestive or cardiovascular system disorders, related to TPH1 activity. In particular, the novel tryptophan hydroxylase inhibitor has an excellent treatment effect on inflammatory bowel disorders, and thus can be usefully used for the treatment of inflammatory bowel disorder. |
US11407762B2 |
Macrocyclic compounds and uses thereof
The present invention provides novel compounds (e.g., compounds of Formulae (I), (II), (III), (IV)) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or pharmaceutically acceptable salts thereof, optionally in a pharmaceutically acceptable carrier, and a medical uses thereof. |
US11407761B2 |
Derivative of β-apopicropodophyllin and method of preparing thereof
Provided are a novel derivative of β-apopicropodophyllin and a method of preparing the same, and more particularly, a compound represented by Formula 1 below, which is a novel derivative of β-apopicropodophyllin derived from podophyllotoxin, which is an anticancer agent, a method of preparing the same, and a composition for treating cancer, which includes the compound. In Formula 1, R is a C2 to C10 alkyl group, a C2 to C10 alkyl group containing an allyl- or alkyne, a —[CH2]n—C3 to C8 cycloalkyl group, a substituted or unsubstituted —[CH2]n-phenyl group, a substituted or unsubstituted —[CH2]n—C5 to C6 heteroaromatic group, a —C(═O)—C1 to C8 alkyl group, a substituted or unsubstituted —C(═O)—[CH2]n-phenyl group, or a substituted or unsubstituted —C(═O)—[CH2]n—C5 to C6 heteroaromatic group, wherein n is an integer of 0 to 6. |
US11407760B2 |
Dioxinoquinoline compounds, preparation method and uses thereof
The present invention relates to a dioxinoquinoline compound of formula (I) or a pharmaceutically acceptable salt thereof. The invention also provides a preparation method of the compound of formula (I) and a pharmaceutically acceptable salt thereof, as well as uses thereof as a drug, wherein the drug acting as a tyrosine kinase (i.e. VEGFR-2 and c-MET) inhibitor is used for treating disorders related to tyrosine kinase. |
US11407758B2 |
Tricyclic compounds, compositions and medicinal applications thereof
The present disclosure relates to a series of tricyclic compounds, their tautomers, polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by adenosine receptor (AR) activity. The disclosure also relates to process of preparation of these tricyclic compounds of Formula I. These compounds are useful in the treatment, prevention or suppression of diseases and disorders that may be susceptible to improvement by antagonism of the adenosine receptor. The disclosure also relates to the process of preparation of the tricyclic compounds, and to pharmaceutical compositions containing them. Formula (I) wherein D represents a tricyclic ring system selected from: Formula (II) or Formula (III). |
US11407757B2 |
Heterocycle compounds as Tyro3, Axl and MerTK (TAM) family of receptor tyrosine kinase inhibitors
Disclosed are compounds of formula (I) below and tautomers, stereoisomers, isotopologues, or pharmaceutically acceptable salts thereof: in which each of variables R1, ring A, L, W, V, and G is defined herein. Also disclosed are a method for treating disease or disorder mediated by Tyro3, Axl, and/or Mer kinase with a compound of formula (I) or a tautomer, stereoisomer, isotopologue, or salt thereof and a pharmaceutical composition containing same. |
US11407756B2 |
Heterocyclic compounds and noxious arthropod control agent containing same
A compound controlling harmful arthropods, represented by formula (I) [wherein Q represents a group represented by Q1 or a group represented by Q2; Z represents an oxygen atom or a sulfur atom; A1 represents a nitrogen atom; A2 represents a CR4a; A3 represents a nitrogen atom or a CR4b; B1 represents a CR1; B2 represents a nitrogen atom or a CR6b; B3 represents a nitrogen atom or a CR6c; R1 represents a C1-C6 chain hydrocarbon group having one or more substituent(s) selected from the group consisting of a cyano group and a halogen atom; R2 represents a C1-C6 chain hydrocarbon group; R3 represents a C1-C6 chain hydrocarbon group; R4a, R4b, R6b, and R6c are identical to or different from each other, and each represent a hydrogen atom; n represents 0, 1, or 2; and q represents 0, 1, 2, or 3] or an N-oxide compound thereof. |
US11407755B2 |
[1,2,4]triazolo[4,3-b]pyridazines for use in the treatment of proliferative diseases
The invention concerns compounds of Formula (I) or pharmaceutically-acceptable salts thereof, wherein R1, R2 and n have any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use as anti-proliferative and/or cell-killing agents. |
US11407752B2 |
Substituted 4,6-dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3′-indoline]-2′,5(3H)-dione analogues
A series of substituted 4,6-dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3′-indoline]-2′,5(3H)-dione analogues, the use thereof and the preparation thereof. |
US11407751B2 |
Hydrochloric acid salt of (6bR,10aS)-3-methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxaline
The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, such as Formula 2J, as shown below, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines, and as further defined herein: |
US11407749B2 |
Heterocyclic compounds as immunomodulators
Disclosed are compounds of Formula (I′), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections. |
US11407748B2 |
Substituted pyrido[1,2-a]pyrimidines and pyrazino[1,2-a]pyrimidines for enhancing AMPA receptor function
The present invention aims to provide a heterocyclic compound having an AMPA receptor potentiator effect, which is expected to be useful as an agent for the prophylaxis or treatment of depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like.The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof. |
US11407746B2 |
Griseofulvin compound and pharmaceutical use thereof
The present invention addresses the problem of providing a compound for prophylaxis and/or treatment of central inflammatory diseases, or a pharmacologically acceptable salt thereof. The present invention addresses a compound of a general formula (I) or a pharmacologically acceptable salt thereof as a means to solve the problem. [R1: a C1-C6 alkyl group or the like, R2: a C1-C6 alkyl group or the like, A: a 5-membered aromatic hetero-ring or the like, R3, R3′: a C1-C6 alkyl group or the like. |
US11407745B2 |
Indazole derivatives and pharmaceutical composition for preventing, alleviating or treating cancer containing the same
Disclosed are a compound selected from novel indazole derivatives, pharmaceutically acceptable salts thereof, hydrates thereof and stereoisomers thereof, a method for preparing the compound, and a pharmaceutical composition for preventing, alleviating or treating cancer containing the compound as an active ingredient. The novel indazole derivatives exhibit excellent ABL/DDR1 inhibitory efficacy and anti-proliferative efficacy against cancer cells, specifically blood cancer cells, and inhibitory activity against ABL T315I point mutations, thus being useful for the prevention, alleviation or treatment of cancer, specifically blood cancer, especially chronic myelogenous leukemia. |
US11407740B2 |
Antibacterial compounds
Provided herein are heterocyclic derivative compounds of Formula (II), and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like. |
US11407737B2 |
Inhibitors of RAF kinases
Provided herein are inhibitors of receptor tyrosine kinase effector, RAF, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases. |
US11407732B1 |
Tricyclic degraders of Ikaros and Aiolos
Tricyclic cereblon binders for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway for therapeutic applications are described. |
US11407729B2 |
Quinoline and quinazoline compounds and methods of use thereof
Compounds and methods for their preparation and use as therapeutic or prophylactic agents, for example for treatment of cancer, bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1). |
US11407728B2 |
Derivatives of EPA endocannabinoid epoxides as anti-inflammatory, anti-cancerous, anti-angiogenc and antiplatelet aggregation compounds
The present disclosure provides chemical compound derivatives of a class of biological lipid mediators known as endocannabinoids and methods of synthesizing the compositions. These compounds are useful for treating cancer, reducing inflammation, reducing platelet aggregation, and reducing angiogenesis. |
US11407727B2 |
Indenyl compounds, pharmaceutical compositions, and medical uses thereof
Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer. |
US11407723B2 |
Selective histone deacetylase inhibitors for the treatment of human disease
Selective HDAC inhibitors, and pharmaceutical compositions that include the same, are described herein for the treatment of cancer, immunological diseases, inflammatory diseases, and neurological diseases. |
US11407714B2 |
Process for producing an organic peroxide
This present disclosure relates to a process for producing an organic peroxide and isolating, purifying, and concentrating the sulfuric acid from the aqueous effluents of said organic peroxide production process. |
US11407711B2 |
Benzamide compound and use thereof
The present disclosure relates to a benzamide compound as shown in Formula I, an insecticidal comprising same, and a use of the compound as an insecticide in the fields of agriculture, forestry and health. |
US11407707B2 |
Treprostinil derivatives and compositions and uses thereof
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension. |
US11407700B2 |
Process for preparing 2,3-unsaturated alcohols
The present invention provides a process for preparing an unsaturated alcohol of the formula (I), wherein one of R1 and R2 is preferably C2-C10-alkyl or C2-C10-alkenyl containing one double bond and the other one is preferably hydrogen or methyl; R3 is preferably hydrogen; which comprises subjecting an educt composition including at least 75% by weight of an unsaturated aldehyde of the formula (II) wherein R1, R2 and R3 preferably have the above defined meanings, to a hydrogenation in the presence of a catalyst and a tertiary amine; wherein the tertiary amine is used in an amount ranging from 0.001 to 0.7% by weight, based on the total amount of the liquid reaction mixture. The invention further relates to the nerol compound obtainable by the inventive process, to a fragrance or aroma substance composition comprising the nerol compound obtainable by the inventive process, to a method for imparting and/or intensifying an odor or flavor of a product, and also to perfumed or aromatized products comprising a nerol compound obtainable by the inventive process. |
US11407698B2 |
Synthesis method for highly selective 2-methylallyl chloride and synthesis reactor thereof
The present invention relates to a synthesis method and synthesis reactor of high-selectivity 2-methylallyl chloride by taking isobutylene and chlorine gas as raw materials and performing a gas-phase chlorination reaction in a microchannel reactor with a cooling surface. The isobutylene and the chlorine gas are reacted in a T-shaped microchannel reactor, and the mixing speed is extremely fast. Meanwhile, the huge heat exchange area per unit volume can ensure that the reaction proceeds stably at a substantially constant temperature and has good controllability. Therefore, side reactions caused by excessive local temperature can be effectively suppressed, the reaction selectivity is high, and no coking phenomenon occurs. |
US11407697B2 |
Process for producing high purity 1-butene
Methods of and systems for producing an olefin are disclosed. A paraffin is dehydrogenated to produce a mixture comprising the olefin and unreacted paraffin. The mixture is then fed to an extractive distillation unit that uses soybean oil as a solvent to extract at least some n-butane from the mixture. |
US11407696B2 |
Apparatus and process for converting aromatic compounds by benzene alkylation with ethanol
Apparatus and process for converting aromatic compounds, comprising/using: a fractionating train (4-7) suitable for extracting at least one benzene-comprising fraction (22), one toluene-comprising fraction (23) and one fraction (24) comprising xylenes and ethylbenzene from the feedstock (2); a xylene separating unit (10) suitable for treating the fraction comprising xylenes and ethylbenzene and producing a para-xylene-comprising extract (39) and a raffinate (40) comprising ortho-xylene, meta-xylene and ethylbenzene; an isomerizing unit (11) for treating the raffinate and producing a para-xylene-enriched isomerizate (42), which is sent to the fractionated train; and an alkylating reaction section (13) for treating at least part of the benzene-comprising fraction with an ethanol source (30) and producing an alkylation effluent (31) comprising ethylbenzene, which is sent to the isomerizing unit. |
US11407695B2 |
Reactors and systems for oxidative coupling of methane
In an aspect, the present disclosure provides a method for the oxidative coupling of methane to generate hydrocarbon compounds containing at least two carbon atoms (C2+ compounds). The method can include mixing a first gas stream comprising methane with a second gas stream comprising oxygen to form a third gas stream comprising methane and oxygen and performing an oxidative coupling of methane (OCM) reaction using the third gas stream to produce a product stream comprising one or more C2+ compounds. |
US11407692B2 |
Method for oxidative cleavage of compounds with unsaturated double bond
A method for oxidative cleavage of a compound with an unsaturated double bond is provided. The method includes the steps of: (A) providing a compound (I) with an unsaturated double bond, a trifluoromethyl-containing reagent, and a catalyst; wherein, the catalyst is represented by Formula (II): M(O)mL1yL2z (II); wherein, M, L1, L2, m, y, z, R1, R2 and R3 are defined in the specification; and (B) mixing the compound with an unsaturated double bond and the trifluoromethyl-containing reagent to perform an oxidative cleavage of the compound with the unsaturated double bond by using the catalyst in air or under oxygen atmosphere condition to obtain a compound represented by Formula (III): |
US11407691B2 |
Nematicidal composition and the use thereof
A composition is provided comprising as component (A) at least one insecticide; and as component (B) at least one fertilizer. The composition is effective in controlling nematodes and in promoting plant growth. The at least one insecticide is preferably selected from thiodicarb, abamectin, imidacloprid, fipronil and mixtures thereof. The fertilizer component preferably comprises one or more amino acids and one or more micronutrients. A method of controlling nematodes and/or promoting plant growth using a combination of component (A) and component (B) is also provided. |
US11407689B2 |
Black urea enhanced efficiency controllable release fertilizer compositions
Calcium cyanamide fertilizer compositions and methods for their use are disclosed. The compositions and methods stabilize active ionic compositions comprising calcium cyanamide and enhance the effectiveness of calcium cyanamide alone or synergistically in combination with nitrogen containing materials such as urea and organics, for example, manures. The compositions and methods also facilitate controllable site directed delivery of the contents of the stabilized compositions. The compositions and methods are effective for fertilizing, soil amending, metal stabilizing and odor and organism inhibition. The compositions are stable, easily calibrated, and non-clogging for spray delivery to target sites. |
US11407685B2 |
Batch for producing a refractory product, method for producing a refractory product, a refractory product and the use of a synthetic raw material
The invention relates to a batch composition for producing a refractory product, a method for producing a refractory product, a refractory product, and to the use of a synthetic raw material. |
US11407667B1 |
Systems and methods for removal of carbon dioxide from seawater
The present invention generally relates to a system and methods for the separation and removal of carbon dioxide from seawater. The system includes an extraction system that collects carbon dioxide from the seawater through a medium, and removes carbon dioxide from the medium; the extraction system comprising a reactor and a membrane. Alternatively, the extraction system includes a reactor, a membrane and a catalyst. |
US11407666B2 |
Salt separation and destruction of PFAS utilizing reverse osmosis and salt separation
Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water is concentrated in a reverse osmosis step and salt from the resulting solution is removed in supercritical conditions prior to destruction of PFAS in supercritical conditions. |
US11407663B2 |
Flow-through electrode capacitive deionization cell
Disclosed here is a capacitive deionization device for removing ions from a target solution. The capacitive deionization device includes a first porous electrode, a second porous electrode, a first header plate, a second header plate, and a sealant. The second porous electrode is disposed below and spaced from the first porous electrode. The first header plate is disposed on the first porous electrode. The first header plate defines an input flow channel that is in fluidic communication with the first porous electrode. The second header plate is disposed below the second porous electrode. The second header plate defines an output flow channel that is in fluidic communication with the second porous electrode. The sealant is disposed between the first header plate and the second header plate and surrounds the first porous electrode and the second porous electrode. |
US11407658B2 |
Passive gravity filter cell and methods of use thereof
A passive filter cell having a basin with a floor and two or more vertical or upright sidewalls forming chute or container having first or left sidewall, second or right sidewall, and third or back sidewall, and fourth or front downwardly curved sidewall, an inlet positioned proximate a top of the fourth or front sidewall and an outlet positioned proximate the top of the third or back sidewall, wherein the floor is configured angled from the fourth or front sidewall to the third or back sidewall, discharge pipe positioned proximate junction between the floor and the third or back sidewall, and lip configured to extend from the top of the third or back sidewall into an interior of the basin. |
US11407655B2 |
System for decontaminating water and generating water vapor
A system and method for decontaminating a fluid and recovered vapor, particularly processing and recycling water used in an oil zone steam process, utilizing a vaporizer-desalination unit to separate a contaminated water flow into a contaminated disposal flow and a clean water vapor flow. The contaminated water flow is recovered after separation from a combined oil and water flow from an oil well. The clean water vapor flow is preferably passed through a steam generator to produce the steam used in the oil zone steam process. The steam is injected into the oil zone of a designated well and then extracted as the combined oil and water flow. Once primed with sufficient external water, the system and method is designed to operate continuously with minimal replenishment because of the water/vapor/steam cycle. |
US11407650B2 |
Method for the reduction of metal halides
The invention relates to a method for producing a compound of formula MXn from a precursor compound of formula MXm, where M is a metal, X is a halide selected from F, Cl, Br, J, m is a number selected from the range 2 to 8, and n is a number selected from the range 1 to 7, with the condition that n |
US11407647B2 |
Synthetic caustic composition
An aqueous caustic composition comprising: a caustic component; an amino acid additive adapted to provide an extended buffering effect to the caustic composition when such is exposed to an acid; and water, wherein the caustic component and the amino acid additive are present in a molar ratio ranging from 15:1 to 5:1. Methods of using such compositions are also disclosed. |
US11407646B2 |
Method for synthesizing ammonia, and apparatus for said method
The purpose of the present invention is to provide a method for synthesizing ammonia and an apparatus for the method. The method for synthesizing ammonia according to the present invention comprises: a step of melting a metal containing at least an alkali metal; and a step of supplying a hydrogen gas and a nitrogen gas to the molten metal. |
US11407644B2 |
Graphene with nanosized openings
Synthesizing holey graphene oxide includes dispersing graphene oxide in an aqueous solution to yield a first graphene oxide dispersion, irradiating the first graphene oxide dispersion with microwave radiation, thereby at least partially reducing the graphene oxide in the first graphene oxide dispersion to yield a second graphene oxide dispersion that includes partially reduced graphene oxide, combining the second graphene oxide dispersion with an etching agent to form a third graphene oxide dispersion, and irradiating the third graphene oxide dispersion with microwave radiation to yield a fourth graphene oxide dispersion comprising holey graphene oxide. |
US11407637B2 |
Direct graphene growing method
A method of preparing crystalline graphene includes performing a first thermal treatment including supplying heat to an inorganic substrate in a reactor, introducing a vapor carbon supply source into the reactor during the first thermal treatment to form activated carbon, and binding of the activated carbon on the inorganic substrate to grow the crystalline graphene. |
US11407636B2 |
Inter-poly connection for parasitic capacitor and die size improvement
The present disclosure, in some embodiments, relates to a method of forming a micro-electromechanical system (MEMS) package. The method includes forming one or more depressions within a capping substrate. A back-side of a MEMS substrate is bonded to the capping substrate after forming the one or more depressions, so that the one or more depressions define one or more cavities between the capping substrate and the MEMS substrate. A front-side of the MEMS substrate is selectively etched to form one or more trenches extending through the MEMS substrate, and one or more polysilicon vias are formed within the one or more trenches. A conductive bonding structure is formed on the front-side of the MEMS substrate at a location contacting the one or more polysilicon vias. The MEMS substrate is bonded to a CMOS substrate having one or more semiconductor devices by way of the conductive bonding structure. |
US11407634B2 |
MEMS actuation systems and methods
A method of manufacturing a micro-electrical-mechanical system (MEMS) assembly includes mounting a micro-electrical-mechanical system (MEMS) actuator to a metal plate. An image sensor assembly is mounted to the micro-electrical-mechanical system (MEMS) actuator. The image sensor assembly is electrically coupled to the micro-electrical-mechanical system (MEMS) actuator, thus forming a micro-electrical-mechanical system (MEMS) subassembly. |
US11407633B2 |
System and method for forming a foundation truss
A system and method for forming a foundation truss for a box spring or mattress foundation frame includes a first truss rail assembly station having a series of block feeders, a top rail hopper and a filler strip hopper that received stacks of truss components such as blocks, top rails and filler strips and feed such truss components into stacked registration. The stacked truss components are moved into engagement with a series of staplers that secure the filler strips, top rails and blocks together to form first truss rail portions, which are then fed to a second truss rail assembly station where a bottom rail is automatically applied thereto. |
US11407632B2 |
Package design for dosing systems and methods of manufacture thereof
Disclosed herein is a dispensable container comprising a container for a fluid; and a fitting for discharging the fluid from the container; wherein the dispensable container is monolithic and where the container and the fitting contact each other seamlessly; and wherein the fitting comprises a conduit that has a higher aspect ratio than the container. |
US11407631B2 |
Cleaning unit for supplying a cleaning liquid to a beverage dispensing system
A cleaning unit (38) for supplying a cleaning liquid to a beverage dispensing system, in which the cleaning unit (38) comprises a first inlet (36) for receiving a pressure fluid, a second inlet (44) for receiving a cleaning liquid, an outlet (42) for supplying the cleaning liquid to a discharge valve of the beverage dispensing system, and a drive mechanism for forcing the cleaning liquid from the second inlet (44) to said outlet (42) by using the pressure fluid received at the first inlet. |
US11407629B1 |
Methods and systems for an intelligent concentrate mixing and delivery device
Intelligent concentrate mixing and delivery devices, systems, and methods are described. An intelligent concentrate mixing and delivery device includes at least one ingredient storage device (e.g., an ingredient cartridge) configured to store one or more ingredients and at least one micro-ingredient pump configured to pump the one or more ingredients into a mixing chamber. The mixing chamber reconstructs at least one finished concentrate from the one or more ingredients. The intelligent concentrate mixing and delivery device further includes at least one pump configured to pump the finished concentrate into a beverage dispensing system. |
US11407628B2 |
Filling system for filling containers with a fluid filling material and filling machine
A filling element includes a radar for measuring fill level in a container during filling thereof and an antenna connected to the radar. The antenna is disposed along a flow path formed in a gas pipe that forms a flow path for fluid while the container is being filled. The antenna provides the radar with a signal indicative of a measurement of a level of the filing material in the container. |
US11407623B2 |
Configurable lift system
A lift system including an extendable column mounted to a wall or free standing on which rides one or more carriages that are raised and lowered by a lifting mechanism. The carriages are removable and capable of having various attachments. |
US11407609B1 |
Wire spool cover
Cover adapted for covering a spool of wire mounted on a shaft for preventing tangling of the wire during use, comprising a first cover portion comprising an outer wall and side walls, and a second cover portion comprising an outer wall and side walls adapted to attach to the shaft adjacent sides of the spool of wire without removing it from the shaft, the first and second cover portions being adapted for mating to cover the wire spool on the shaft, the second cover portion comprising an opening for allowing the wire on the spool to pass through the outer wall and allowing the spool of wire to rotate freely on the shaft to dispense the wire in a tangle-free manner from the spool as the wire is pulled through the opening. |
US11407604B2 |
Sheet suction device, sheet conveyor, printer, and suction area switching device
A sheet suction device includes a sheet bearer having a plurality of suction holes on a plurality of bearing areas, a rotational portion having a plurality of holes that is connectable to the plurality of suction holes, a suction unit configured to suck air via the plurality of holes of the rotational portion. The sheet bearer bears a plurality of sheets on the plurality of bearing areas of the circumferential surface of the sheet bearer and rotates. The rotational portion rotates in a same cycle of the sheet bearer. The sheet suction device further includes a switching unit that switches combinations of whether or not to suck the air among the plurality of bearing areas of the sheet bearer according to a phase of rotation of the sheet bearer or the rotational portion. |
US11407597B2 |
System and method for processing irregular parcels
A system for sorting and delivering packages to one of a plurality of loading points includes a first movable cart positioned adjacent a first conveyor in a receiving position to receive packages from the first conveyor, a second movable cart positioned in a staging position, the second movable cart being empty, and a vehicle selectively engageable with the second movable cart to move the second movable cart from the staging position to the receiving position while simultaneously abutting and displacing the first movable cart from the receiving position to a transfer position. |
US11407595B2 |
Methods and apparatuses for performing article singulation
Methods and apparatuses for performing article singulation are provided. An article singulator can include an intake conveyor, an out-take conveyor, and multiple intermediate conveyors. The intake conveyor can receive multiple articles and convey the articles to the multiple intermediate conveyors. Further, the out-take conveyor may convey singulated articles from amongst the multiple articles (e.g. to an outfeed). Further, the multiple intermediate conveyors may include successive conveyors to convey the articles and provide the singulated articles to the out-take conveyor. In some examples, each successive conveyor of the multiple intermediate conveyors may be positioned at a lower level than a preceding conveyor. Further, each successive conveyor can convey the articles in a different direction and at a different speed than a preceding conveyor such that the articles are singulated upon conveyance by the article singulator. |
US11407594B2 |
Method for tracking packages on a conveyor section
In a method for tracking packages on a conveyor section, the tracking rate of packages is intended to be maximized. This is achieved by providing a method for tracking packages on a conveyor section, the method comprising the following steps: a) providing a conveyor section having a conveyor surface for conveying a sequence of packages, the conveyor section comprising at least one photoelectric barrier for detecting the packages, b) detecting a photoelectric barrier pattern by means of the photoelectric barrier, the photoelectric barrier pattern being caused by the sequence of packages, c) detecting a conveyor speed of at least one subsection of the conveyor section, d) estimating an event sequence which has with the highest probability caused the photoelectric barrier pattern, while taking into account the conveyor speed of the conveyor section, by means of an algorithm, the algorithm comprising the following further steps: e) compiling a list of possible event sequences, f) sorting the event sequences with the aid of their occurrence probability, g) extending the most probable event sequence by all possible consecutive events, the probability of the event sequence being determined for each extension, h) incorporating the extensions as a new event sequence into the list of event sequences, i) repeating steps g) to h) until the most probable event sequence fully reflects the detected photoelectric barrier pattern. |
US11407587B1 |
Automated container retrieval and delivery systems
Systems, methods, and apparatuses are disclosed for automated container retrieval and delivery systems. In one embodiment, an example container handling system may include a platform, a first rotatable arm disposed on a lower side of the platform, where the first rotatable arm is offset from a front end of the platform, a motor configured to rotate the first rotatable arm from a first position to a second position, and a first wheel disposed at a distal end of the first rotatable arm. The container handling system may be configured to raise a container from an angled position to a horizontal position, and the container may be in the horizontal position when the first rotatable arm is in the second position. |
US11407585B2 |
Automatic control of a refuse front end loader
An automatic control system for a refuse vehicle includes a mode select switch disposed within the vehicle that generates a mode select signal based on input from an operator of the vehicle, a control mechanism disposed within the vehicle that operates in response to the mode select signal, and a plurality of sensors adapted to sense a plurality of characteristics of the vehicle and adapted to communicate the plurality of sensed characteristics. The system further includes a control module that receives control instructions from the control mechanism and selectively controls at least one component of a plurality of components of the vehicle based on the mode select signal, at least one of the plurality of sensed characteristics, and the control instructions. |
US11407578B1 |
Disposable beverage container sleeve and coaster
A unitary disposable beverage container sleeve that can also be used as a coaster and that can be comprised of (optionally recyclable) cardstock for economically imprinting with advertising logos or slogans. The upper body vertical rectangular edges are connected to form sides of the sleeve and a gusset extends across the diameter at the lower edge to form the base of the sleeve. The gusset has a hinge that opens and closes the sleeve. Arched grooves positioned at that lower edge above the gusset where the gusset attaches to opposing sides of the sleeve allows flex in the sleeve and affords a level base. |
US11407577B1 |
Microwave popcorn bag
A microwave popcorn bag for containing and heating popcorn kernels in a microwave oven. The bag is constructed of a laminated fibrous material and comprises a base panel, top panel, side panels, and interior space. The side panels have gussets with fold areas and fold lines that are adjacent to the base panel and that enable the bag to expand. An oil-resistant microwave susceptor film is laminated with the fibrous material and extends laterally across the base panel and the fold lines into the fold areas. Microwave interactive material is confined to the base panel. As the popcorn is heated, the bag expands and the microwave susceptor film forms a tray structure that collects oil and resists it penetrating through the fibrous material. |
US11407576B2 |
Patterned dual susceptor
A microwave packaging material including a plurality of susceptors is disclosed. Each susceptor includes a plastic film or polymer with a metal layer on one surface of the plastic film and a paper adhered to the plastic film opposite the metal layer. A patterned adhesive is bonded between a first susceptor layer and a second susceptor layer in a pattern bond creating sealed air pockets. A paper board substrate is adhered using an adhesive in a bond pattern to one of the susceptor layers facing the metal of the respective susceptor layer to provide the microwave packing material rigidity. Upon exposure to microwave energy in a microwave oven, moisture is trapped between the paper board substrate and the susceptor layer creating a vapor pressure that causes the sealed air pockets to form expanded air pockets. |
US11407573B2 |
System for transporting fragile objects
According to certain embodiments, a vibration-isolating system comprises a platform adapted to carry one or more loads and an adjustable load-positioning system. The platform is suspended within a support structure by a plurality of isolators. The isolators are tuned to impede vibrations in a pre-determined frequency range for a payload having a pre-determined mass. The adjustable load-positioning system is adapted to facilitate positioning the one or more loads such that the payload having the pre-determined mass is centered at the center of gravity of the platform. |
US11407564B2 |
Cap assembly
The present application is directed to cap assemblies and particularly, cap assembly for closing an opening in a vessel, the cap assembly including a stopper including an polymer body adapted to fit an opening of a vessel, the stopper also including a tubular portion which defines an internal passageway extending through the polymer body; and a rigid cap attached to and integral with the stopper, wherein the cap is adapted to engage the vessel and provide a sealing force between the stopper and the vessel. |
US11407560B2 |
Liquid container having integrated auxiliary flask
A liquid container having an integrated flask is defined by an outer wall having a recess. A flask is configured to fit within the recess. Tabs for lips extend partially over the recess from the outer wall of the bottle and secure the flask with in the recess by a snap fit. The flask may be removed from the bottle and filled with a lesser amount of liquid and used when traveling. |
US11407558B2 |
Shipping frame and shield
An improved shipping frame for use with storage and/or transporting goods includes four corner posts and a top surface and a bottom surface. The corner posts comprise of telescoping leg sections whereby the smaller dimensioned section fits within the larger dimensioned section and can be locked at a particular height. A shield assembly comprises a rear shield and two side shields is affixed to the top section of the frame to brace any upper load therein. |
US11407554B2 |
Reclosable folding box with a tamper-evident closure, and folding box blank for producing same
In a reclosable folding box (41, 42, 43) having a safety and tamper-evident closure (84), the side wall surfaces (2 to 6, 64, 65) of which are formed by a one-piece blank (1, 1a, 1b) and glued together in such a way that the folding box (41, 42, 43) cannot be opened without destroying a glued joint and/or at least one disconnectable tear line area (16, 17, 16a, 16b, 17a, 17b), a solution for a reclosable medical packaging having a safety and tamper-evident closure is to be created, which provides an improved graspability and visual recognizability of a pull tab forming at least the substantial part of the safety and tamper-evident closure. This is achieved by the fact that the pull tab (18) reaches a folding box edge (39, 52) with an edge-side boundary line (85) and is printed on a folding box outer side with a first linear pattern (20), in particular a guilloche pattern, extending at least in part with at least one pattern line beyond the tear line area(s) (16, 17, 16a, 16b, 17a, 17b), which first linear pattern (20) adjoins an area (21, 22) visible from the folding box outer side and printed in contrast color with respect to the first linear pattern (20), which is formed in a way to encompass, at least to include the pull tab (18), in the area of an edge-side limiting edge (86) of the pull tab (18) on the outer side on a first side wall surface (2), or which is formed in the area of the boundary line (85) at least on a surface area of a second side wall surface (3) facing the folding box outer side and covered by the pull tab (18), as well on the outer side of a third side wall surface (4) hinged to the second side wall surface (3) and adjoining the pull tab (18), in a way to graduate into the same. |
US11407544B2 |
Part packing system and method
A part packing system for packing a part in an elongated bag includes a bag holding machine including a first bag gripper mechanism, a second bag gripper mechanism, and an air nozzle. The first bag gripper mechanism is configured to hold a first end of the elongated bag. The first bag gripper mechanism opens the first end of the elongated bag. The second bag gripper mechanism is configured to hold a second end of the elongated bag. The second bag gripper mechanism closes the second end of the elongated bag. The air nozzle is located proximate to the first bag gripper mechanism. The air nozzle is configured to inflate the elongated bag with an airflow directed into the first end of the elongated bag. The first bag gripper mechanism holds the inflated elongated bag with the first end open to receive the part in the open first end while the air nozzle directs the airflow into the elongated bag. |
US11407541B2 |
Large industrial vacuum sealer system
The present invention proposes a large industrial vacuum sealer system. The system comprises the following working steps: after materials are placed, a box base moves upwards to be jointed with a box cover in a sealing manner; the first valve 120 is switched on; a rotary vane pump starts roughly pumping the air; next, a roots pump starts working; when the pressure reaches a preset value, the first valve 120 is switched off; valves 110 and the second valve 130 are switched on; diffusion pumps start working; after the air is pumped out completely, all pumps stop working. A box body comprises the box cover and the box base, wherein the box body is fixedly mounted. The box base is driven by air cylinders to move along a rail. In the present invention, a light curtain sensor is mounted between the box cover and the box base. |
US11407539B2 |
Apparatus and method for constructing a package
Aspects of the disclosure relate to an apparatus and method of packaging one or more articles. The device being adapted to applying a plurality of top-engaging carriers to a plurality of groups of articles simultaneously. The device comprises a metering base for facilitating arranging a plurality of articles into groups of articles and an applicator for pressing top-engaging carriers onto groups of articles. The metering base comprises a spacer structure for maintaining a predetermined space between each group of articles and at least a next adjacent group of articles; and a first aligning feature. The applicator comprises an applicator plate having a plurality of receiving cavities each for receiving a top of an article and a second aligning feature for engaging the first aligning feature for sliding movement with each other. |
US11407532B2 |
Innovative system for deploying satellites from launch vehicles
The invention concerns a satellite deployment system (30) for launch vehicles. Said satellite deployment system (30) comprises an outer dispenser (31) that is fitted, externally, with first releasable attachment means for releasably attaching first satellites (81) to said outer dispenser (31) and, internally, with an internal housing volume (310). Moreover, the satellite deployment system (30) further comprises at least an inner dispenser (32,33) that is externally fitted with second releasable attachment means for releasably attaching second satellites (82,83) to said inner dispenser (32,33), and that is accommodated in the internal housing volume (310) of the outer dispenser (31). |
US11407511B1 |
Delivery drop platforms, tethers, and stabilization
An unmanned aerial vehicle (UAV) can deliver a package to a delivery destination. Packages delivered by a UAV may be lowered towards the ground while the UAV continues to fly rather than the UAV landing on the ground and releasing the package. Packages may sway during lowering as a result of wind or movement of the UAV. A package sway may be monitored and mitigated by rapidly paying out a tether, when using a winch mechanism, to dissipate the energy of the sway as downward energy. Further, the UAV may navigate in the direction of the sway or reduce the altitude of the UAV to dissipate the energy of the sway. Open-loop and/or closed loop drop techniques may be utilized to lower a package from the UAV, and the package may be released in the air or on the ground. |
US11407507B2 |
Lift rotor system
A lift rotor arrangement (100) for a VTOL aircraft (200). The lift rotor arrangement (100) comprises: a fairing (6) mounted on a wing segment (10); and first and second rotor blades (17, 18) mounted on a first shaft (4) extending vertically from the fairing (6). The first shaft (4) is movable between an extended position in which the first and second rotor blades (17, 18) are vertically spaced above the wing segment (10) and are rotatable to provide vertical lift, and a retracted position in which the first and second rotor blades (17, 18) are rotationally-fixed with the first rotor blade (17) stowed within the wing segment (10). The blades (17, 18) may be rotatable around an axis substantially perpendicular to the axis of the respective first shaft (4) so as to act as ailerons/elevons in the retracted position. |
US11407505B2 |
Dynamically adjustable rotorcraft swashplate with undulating surface
A rotorcraft swashplate assembly includes a rotationally fixed swashplate fixed against rotating with a rotorcraft rotor. The swashplate assembly also includes a rotatable swashplate coupled to the rotor to rotate with the rotor. The swashplate assembly also includes multiple pitch change links, each pitch change link coupled to a respective rotor blade and to the rotatable swashplate to rotate with the rotor. The swashplate assembly also includes an annular track coupled to the rotationally fixed swashplate and configured to support each pitch change link riding on the annular track as each pitch change link rotates with the rotor. The track includes multiple bearings upon which a pitch change link rides, and actuators that move the bearings changing a shape of the annular track and thereby the pitch of each rotor blade as each pitch change link rides on the annular track during rotation of the rotor blades. |
US11407501B2 |
Roller gear for a drive system
A roller gear for use in a roller gear and sprocket configuration of a drive system is disclosed, particularly for use in a landing gear drive system of an aircraft. Alternative embodiments and, in particular, means for permitting removal and replacement of rollers and roller mounting pins in the roller gear are disclosed. |
US11407499B2 |
Aircraft landing gear having a lever assembly, aircraft including the same, and related methods
An aircraft landing gear structure includes a strut assembly and a wheel assembly operatively coupled to the strut assembly. The strut assembly includes an upper tubular housing and a lower tubular housing configured to be longitudinally translated with respect to the upper tubular housing such that the overall length of the strut assembly is transitioned between an extended configuration and a retracted configuration for stowage during flight. The wheel assembly includes a forward link pivotally coupled to the upper tubular housing and a truck beam that is pivotally coupled to the lower tubular housing such that translation of the lower tubular housing with respect to the upper tubular housing causes pivoting of the forward link and the truck beam with respect to one another, thereby tilting and/or raising a wheel of the wheel assembly with respect to the upper tubular housing. |
US11407497B2 |
Cavity acoustic tones suppression
A cavity system, comprising: a cavity (2) comprising a cavity opening; and an acoustically reflective structure (18, 20) located at least partially within the cavity (2), the acoustically reflective structure (18, 20) comprising one or more acoustically reflective surfaces (24, 26, 30, 32), each acoustically reflective surface (24, 26, 30, 32) being oblique to a plane of the cavity opening (27). The one or more acoustically reflective surfaces (24, 26, 30, 32) may be arranged to reflect incident acoustic waves out of the cavity opening while avoiding reflection into a region (48) at or proximate to a leading edge (14) of the cavity (2). |
US11407495B2 |
Actuator assembly for a high-lift device, wing assembly and aircraft equipped with such an actuator arrangement
To improve reliability and safety of an actuator assembly for a high-lift device, a torque sensing device is provided on a static structural part, which is used to mount the actuator of the actuator assembly to an aircraft interface, such as a rib or an interconnection strut. A controller determines a reaction torque value based on the output signal of the torque sensing device and monitors and controls the actuator based on the reaction torque value and predetermined load thresholds. |
US11407494B2 |
Pitch control assembly
A method of controlling a propeller assembly, having a blade, piston end cap, and piston, with a pitch control unit, having a transfer bearing and a blade angle unit, the method comprising: axially moving a transfer tube relative to and circumscribing the transfer bearing, and sensing an axial movement of the transfer tube with the blade angle unit. |
US11407493B2 |
Rotating shroud for rotator blade systems
A system and method for improving the flight control and efficiency of an aerial vehicle. Many embodiments are directed to a rotor-shroud assembly system where a plurality of rotor blades are connected to the internal side of a shroud and are set up to pivot through the use of a pitching mechanism. The entire assembly is configured to rotate when attached to a motor. |
US11407492B2 |
Control surface for an aircraft and control structure for an aircraft with anti-flutter balance weight
A leading edge (3) of a control surface (1) for an aircraft includes a balance weight (6) attached to the forward-most region of the leading edge (3). The control surface (1) rotates with respect to the stabilizer (2) around a hinge line (5). The balance weight (6) is ahead of and adjacent to the most frontal portion (7) of the leading edge (3) of the control surface (1) are is inside the trailing edge of the stabilizer (2). This arrangement allows to have an anti-flutter balance weight without any impact in aerodynamic drag. |
US11407491B2 |
Lift-sharing wing with rotatable trailing edge
One embodiment includes a rotary aircraft, including: a rotary propulsion system; a body; and a pair of wings connected on opposite sides of the body, wherein each of the wings includes a flap rotatably connected to a trailing edge thereof and configured to rotate downward relative to the wing during low speed and stationary flight of the aircraft, and to rotate upward relative to the wing during high-speed flight of the aircraft. |
US11407490B2 |
Aircraft structural component with aircraft skeleton component and fluid conduit component
An aircraft structural component is described, including an aircraft skeleton component which divides a space along a longitudinal axis of the aircraft skeleton component into two spatial portions arranged on opposite sides of the aircraft skeleton component, and including a fluid conduit component which runs on an outer side of the aircraft skeleton component and fluidically connects the two spatial portions. Also described is an aircraft wing with an aircraft structural component, as well as an aircraft with an aircraft structural component or with an aircraft wing. |
US11407487B2 |
Unitary aircraft windshield with conical single curvature
A windshield for an aircraft cockpit is provided which includes a glazed windshield part which has a single curvature corresponding to a portion of the envelope of a cone extending between a lower plane and an upper plane which intersect an axis of the cone. The single curvature of the glazed part of the windshield enables the glazed part to be produced more easily, for example by rolling or by hydroforming. It also makes it possible to create configurations for a cockpit for two pilots, a single pilot or even no pilot, on the basis of a single aerodynamic shape of the fuselage of the aircraft by only adapting the structure of the windshield. Also provided are a windshield frame for such a windshield, a windshield assembly including such a windshield frame and such a windshield, and an aircraft equipped with such a windshield. |
US11407481B1 |
Trolling motor control system
A trolling motor control system to control the operation of a trolling motor including a rotatable propulsion support shaft to couple a propulsion unit to a boat including a plurality of modules and one or more control devices including a foot pedal control having a foot pedal pivotally mounted to the deck of the boat wherein the plurality of modules includes logic and circuitry to send and receive signals between the modules and to send and receive signals to and from the foot pedal control to synchronize or align the corresponding angular position of rotatable propulsion support shaft in the horizontal plane relative to the longitudinal axis of the boat with the angular position of the foot pedal control in the vertical plane relative to the deck of the boat and to generate tactile feedback to the pivotal foot pedal. |
US11407479B2 |
Jet propulsion watercraft
A jet propulsion watercraft includes a vessel body, a jet pump that is disposed at the vessel body and that includes a water jet opening, and a first guide that is attached to the vessel body. The jet pump generates a thrust by sucking in water existing around the vessel body and jetting the water from the water jet opening. The first guide receives water flowing on a lateral side of the vessel body and generates a downforce that generates a wake behind the vessel body. |
US11407478B2 |
System for storing and transporting a cryogenic fluid on a ship
An installation for storing and transporting a cryogenic fluid on a ship includes: a sealed and thermally insulating tank, having a ceiling wall including, from the outside to the inside, a primary thermally insulating barrier and a primary sealing membrane intended to be in contact with the cryogenic fluid; and a sealed line penetrating through the ceiling wall of the tank, the line including a bottom portion of which a first end is situated inside the ceiling wall of the tank and a second end is situated outside the ceiling wall of the tank in a thicknesswise direction of the ceiling wall, and a top portion fixed to the second end of the bottom portion. The bottom portion includes an alloy with low thermal expansion coefficient. The primary sealing membrane is tightly fixed to the bottom portion of the line around the line. |
US11407477B2 |
System and method for enhancing a wake profile for pontoon boats
A system for enhancing a wake profile produced by a pontoon boat is provided. The system includes a pair of ramps attached to the bottom of a platform supported by at least two pontoons. The ramps may be oriented downward with a rear end of the ramp disposed in the water between the pontoons. The water flowing between the pontoons is displaced downward by the ramps, thereby increasing water displacement and directing the water to produce an improved wake profile. Downforce may be applied to the boat by one or more wake plates, with a faceted portion of the wake plate facing forward and upward, such that when water impacts the faceted portion a downforce is provided. The wake plates may be attached to the ramps or may be separate from the ramps. |
US11407476B2 |
Derailleur for human-powered vehicle
A derailleur comprises a base member configured to be attached to a human-powered vehicle frame, a movable member movable relative to the base member, a pulley assembly configured to be pivotally attached to the movable member with respect to a pivot axis, and a biasing member configured to apply biasing force to the pulley assembly. The biasing member includes a first biasing member and a second biasing member. |
US11407475B2 |
Bicycle derailleur
A user interface of a bicycle derailleur is configured to receive a user input to execute at least one of: calibration in which a sensor is reset; changing an assist operation of an assist driving unit; changing information displayed in a display; a recovering operation by an actuator of the bicycle derailleur; a reset of a pairing operation; changing a shifting threshold used in an automatic shifting mode; changing a communication channel between a wired communication channel and a wireless communication channel; changing a function assigned to an operating device; a shut-down of a system of the bicycle derailleur; a wake-up operation of the system; a restart of the system; an operation of at least one additional bicycle component; changing a shifting mode between the automatic shifting mode and a manual shifting mode; and changing the shifting operation between a synchronized shifting mode and a non-synchronized shifting mode. |
US11407474B2 |
Operating device for human-powered vehicle
An operating device for a human-powered vehicle comprises a base member, an informing unit, and an operating member. The base member is configured to be mounted to a handlebar. The informing unit is configured to inform a user of first information relating to an assist driving unit configured to assist a human power. The operating member is movably coupled to the base member to control a component different from the assist driving unit. |
US11407473B2 |
Operating device and assist driving system for human-powered vehicle
An operating device for a human-powered vehicle comprises a base member, an operating member, and an assist operating interface. The base member includes a coupling end, a free end, and a grip portion. The coupling end is configured to be coupled to a handlebar. The free end is opposite to the coupling end. The grip portion is provided between the coupling end and the free end. The operating member is pivotally coupled to the base member about a pivot axis. The assist operating interface is configured to receive a first user input indicating that an assist driving unit generates a temporary assist driving force for a limited period corresponding to an operation of the first user input. |
US11407472B2 |
Human-powered vehicle control device
A human-powered vehicle control device includes an electronic controller configured to control an electric component of a human-powered vehicle including a crank and a drive wheel. The electronic controller is configured to control the electric component so as to change at least one of a first ratio of a rotational speed of the drive wheel to a rotational speed of the crank and a second ratio of a drive force assisting propulsion of the human-powered vehicle to the human drive force upon determining a human drive force input to the crank shifts from a first range to outside the first range. The electronic controller is configured to change the first range in accordance with at least one of a state of a rider and a running state of the human-powered vehicle. |
US11407467B2 |
Stable balance controller
According to one aspect, a control system for providing stable balance control may include an H∞ controller, a state-feedback circuit, a first feedback loop, and a second feedback loop. The control system may be implemented in a robot as a controller for the robot. The H∞ controller may receive an input signal and generate a control effort signal. The state-feedback circuit may receive the control effort signal as an input and generate an output signal. The feedback loop may include the H∞ controller and the state-feedback circuit and may transfer the output signal of the state-feedback circuit back to the input of the H∞ controller and input a tracking error input signal to the H∞ controller. The tracking error input signal may be the difference between the output signal of the state-feedback circuit and the input signal. |
US11407463B2 |
Headlamp device including headlamp and pair of cornering lamps
A headlamp device for use in a leaning vehicle, including at least one headlamp that emits light in a front direction, and a pair of cornering lamps that emit light to form left-front and right-front light emission areas. Each of the at least one headlamp includes at least one headlamp light source, and a headlamp housing that stores the at least one headlamp light source and that is arranged inside the front cover. Each cornering lamp includes at least one cornering lamp light source, a light travel direction changing member having a light travel direction changing surface that changes a travel direction of light outputted from the at least one cornering lamp light source, and a cornering lamp housing that stores therein the at least one cornering lamp light source and the light travel direction changing member, and that is arranged inside the front cover. The cornering lamp housing and the headlamp housing are separate from each other. |
US11407462B2 |
Vehicle operation with interchangeable drive modules
Vehicles may be composed of a relatively few number of “modules” that are assembled together during a final assembly process. An example vehicle may include a body module, a first drive module coupled to a first end of the body module, and a second drive module coupled to a second end of the body module. One or both of the drive modules may include a pair of wheels, a battery, an electric drive motor, and/or a heating ventilation and air conditioning (HVAC) system. One or both of the drive modules may also include a crash structure to absorb impacts. If a component of a drive module fails or is damaged, the drive module can be quickly and easily replaced with a new drive module, minimizing vehicle down time. |
US11407461B2 |
Attaching doors to vehicles
A method of assembling a vehicle is disclosed, comprising the steps of (in sequence) providing a chassis structure, affixing a door inner panel to the chassis structure via a hinged attachment, at a location adjacent to a door opening defined by the chassis structure, attaching at least one external body panel to the chassis structure, attaching a door outer panel to the door inner panel via an adhesive fixing. In this way, the door inner panel can be attached in place during the build, at a position tailored to the needs of the seals provided between the door and the chassis structure. Production of the vehicle can continue, and in due course the exterior body panels can be fitted to the chassis structure. The door outer panel can then be attached to the door inner panel, using the tolerance in the adhesive attachment to adjust for panel gap and flushness of fit. The application also relates to a vehicle made in this way. |
US11407460B2 |
Nonlinear walking apparatus
A load transporting apparatus is configured to move a load bearing frame carrying a load over a base surface. A support foot provides a first load bearing surface. A lift mechanism during a step operation raises the support foot off of the base surface, lowers the support foot onto the base surface, and raise the load off of the base surface. A first travel mechanism moves the lift mechanism and attached load along a non-linear horizontal path and a second travel mechanism moves the lift mechanism along a different horizontal path. A control system operates the first travel mechanism and the second travel mechanism to move the lift mechanism along a selected horizontal path. |
US11407459B1 |
Lubricating oil maintenance cap assembly with thermally resistant shield
A lubricating oil maintenance cap assembly includes a cap having an outer side, and an inner side, a shield, anchor assemblies, the shield is applied to the inner side of the cap, and the anchor assemblies anchor the shield to the cap. The cap is fashioned of a first material, the shield is fashioned of a second material, and the second material is different from the first material and is more thermally resistant than the first material enabling the shield to thermally shield the inner side of the cap. |
US11407456B2 |
Rotating spare tire lift system
A system for accessing a wheel of a vehicle includes a support, a carrier, and a hinge joint. The support is affixed in a recess of a vehicle bed, and is positioned below the surface of the vehicle bed. The carrier is configured to be affixed to the wheel. When the carrier is affixed to the wheel, both the carrier and the wheel are accommodated in the recess and move as a substantially rigid body. The hinge joint couples the support and the carrier. The hinge joint has an axis substantially parallel to the ground and laterally across the vehicle bed. The carrier is capable of rotating about the hinge joint. The carrier and the wheel are capable of being rotated about the hinge joint out of the recess and onto the vehicle bed. One or more rotational elements may be included to affect rotational motion of the carrier. |
US11407455B2 |
Efficient autonomous trucks
The technology relates to enhancing the operation of autonomous vehicles. Extendible sensors are deployed based on detected or predicted conditions around a vehicle while operating in a self-driving mode. When not needed, the sensors are fully retracted into the vehicle to reduce drag and increase fuel economy. When the onboard system determines that there is a need for a deployable sensor, such as to enhance the field of view of the perception system, the sensor is extended in a predetermined manner. The deployment may depend on one or more operating conditions and/or particular driving scenarios. These and other sensors of the vehicle may be protected with a rugged housing, for instance to protect against damage from the elements. And in other situations, deployable foils may extend from the vehicle's chassis to increase drag and enhance braking. This may be helpful for large trucks in steep descent situations. |
US11407452B2 |
Vehicle body structure member
Provided is a vehicle body structure member molded by a die. The vehicle body structure member includes a general portion constituting a main part of the vehicle body structure member, ribs provided in a standing manner from the general portion, and thickened portions provided in a standing manner from the general portion, each of the thickened portions being thicker than each of the ribs. |
US11407451B1 |
Canopy for lightweight vehicle
A canopy for a lightweight vehicle comprising a canopy main panel mountable to a hollow front canopy downspout-strut. The main panel including a first water channel extending, a second water channel extending, a forward water channel integrally and fluidly connected to the first water channel and the second water channel. The main panel additionally including at least one water egress orifice formed in a bottom of an intermediate portion of the forward water channel, and a spout extending from a perimeter of each egress orifice, the spout integrally formed with and extending from an underside of the main panel, wherein each spout is structured and operable to extend into a water ingress opening in the front canopy downspout-strut of the vehicle when the canopy main panel is mounted to the front canopy downspout-strut. |
US11407450B2 |
Reinforcement for a vehicle
There is provided a reinforcement for a vehicle having a main body portion that is formed in a hollow beam shape, and extends in a vehicle width direction while having both end portions thereof in the vehicle width direction supported by structural components of a vehicle, and whose cross-sectional surface area in a vehicle front-rear direction becomes progressively larger from the end portions in the vehicle width direction towards a central portion thereof. |
US11407445B2 |
Electric power steering system
An electric power steering system includes an electric motor, a rotational angle detection unit, a current detection circuit, a steering torque detection unit, a target torque setting unit, a current command value setting unit, and a current control unit. The target torque setting unit includes a basic target torque setting unit, a first compensation value computation unit, a second compensation value computation unit, and a correction unit. The basic target torque setting unit sets basic target torque for the electric motor. The first compensation value computation unit sets a first compensation value based on steering torque. The second compensation value computation unit computes a second compensation value which is an estimated value of disturbance torque other than the steering torque. The correction unit corrects the basic target torque. |
US11407442B2 |
Steer-by-wire system
A steer-by-wire system includes a transmission torque sensor, a handwheel position sensor, and a controller. The transmission torque sensor is configured to measure and output a transmission torque signal. The handwheel position sensor is configured to measure and output a handwheel position signal. The controller includes an angle-based load calculation submodule, a torque steer ratio calculation submodule, and a torque control module. The angle-based load calculation submodule is configured to transform the transmission torque signal and the handwheel position signal into an estimated second load value. The torque steer ratio calculation submodule is configured to transform the estimated second load value, a first load value indicative of roadwheel load including torque steer influence, and the transmission torque signal into a torque steer ratio. The torque control module is configured to transform the first load value, the handwheel position signal, and the torque steer ratio into a handwheel torque command signal. |
US11407439B2 |
Steering shaft assembly
A steering shaft assembly includes a first member having a first member inner surface and a first member outer surface. Each surface extending between a first member first end and a first member second end along an axis. A second member having a second member inner surface and a second member outer surface. Each surface extending between a second member first end and a second member second end along the axis. The first member first end arranged to be received within the second member such that the second member inner surface is disposed about a portion of the first member outer surface. Also included is a shaft extending from a third member. The shaft extending into the first member second end along the axis. |
US11407435B2 |
Articulated joint connection device, and coupling device with a coupling bar with coupling bar parts which can be connected via an articulated joint connection device
An articulated joint connection device force-transmits the connection of two components, each extending along a common longitudinal axis in a first working position, and for pivoting one of the two components relative to the other component about a pivot axis, which is arranged perpendicularly and parallel to the longitudinal axis, into at least one other, second working position. Furthermore, a coupling device, particularly for rail vehicles, has a coupling bar with two components which are coupled together via such an articulated joint connection device. The design configuration of the coupling elements is characterized by a drawbar sleeve joint connection. |
US11407434B2 |
Rubbing plate of side bearer of railcar bogie and side bearer
A rubbing plate of a side bearer of a railcar bogie is a rubbing plate of a side bearer provided at the railcar bogie so as to slidably contact a slide member arranged above or under the side bearer. The rubbing plate includes a recess-projection provided on an opposing surface of the rubbing plate, the opposing surface being opposed to a sliding surface of the slide member. |
US11407433B2 |
Articulated vehicle having a passage with a noise insulating layer
The invention relates to an articulated vehicle including a plurality of vehicles or vehicle parts connected to one another in an articulated manner, a passage arranged between adjacent ones of the vehicles or the vehicle parts, the passage having an inner lining and an outer lining laterally spaced from the inner lining so as to define an empty cavity therebetween, one front wall on each side of the passage between the two adjacent vehicles or vehicle parts, the inner lining and the outer lining being arranged at the front walls of the two adjacent vehicles or vehicle parts while forming the empty cavity therebetween, a noise-absorbing noise insulation layer applied to a free surface on each of the front walls in the empty cavity between the inner and outer lining, wherein each of the noise-absorbing noise insulation layer extends into the empty cavity and terminates at a surface facing opposite to the each of the front walls respectively. |
US11407432B2 |
Connectivity-enabled traffic-aware supplemental sensor control for informed driving
A sensor control system for a vehicle includes one or more processors and a memory communicably coupled to the one or more processors. The memory stores a zone of interest determination module including computer-readable instructions that when executed by the one or more processors cause the one or more processors to determine if at least one localized zone of interest resides within a preliminary zone of interest of the vehicle. The memory also stores a sensor control module including computer-readable instructions that when executed by the one or more processors cause the one or more processors to control one or more operational parameters of at least one sensor so as to, if at least one localized zone of interest resides within the preliminary zone of interest, bring at least a portion of the at least one localized zone of interest into a of field view of the at least one sensor. |
US11407429B2 |
Road resource conflict resolution algorithm
A road resource is identified, according to one or more maneuver sharing intent messages received to the vehicle via a transceiver of a vehicle, where the road resource is contested between the vehicle and one or more other vehicles and includes a portion of a roadway to be traversed by the vehicle and also the one or more other vehicles. A conflict resolution procedure is performed to determine whether the vehicle gains access to the road resource, wherein the conflict resolution procedure is independently performed by each of the vehicle and the one or more other vehicles. One of the vehicle or the one or more other vehicles is granted access to the road resource based on the conflict resolution procedure. |
US11407423B2 |
Ego actions in response to misbehaving vehicle identification
Systems, apparatus, methods, and techniques for an ego vehicle to respond to detecting misbehaving information from remote vehicles are provided. An ego vehicle, in addition to reporting misbehaving vehicles to a misbehavior authority via a vehicle-to-anything communication network, can, take additional actions based in part on how confident the ego vehicle is about the evidence of misbehavior. Where the confidence is high the ego vehicle can simply discard the misbehaving data and provide an alternative estimate for such data from alternative sources. Where the confidence is not high the ego vehicle can request assistance from neighboring vehicles and roadside units to provide independent estimates of the data to increase confidence in the evidence of misbehavior. |
US11407422B2 |
Operation appropriateness determination system, method for determining operation appropriateness, and non-transitory computer readable medium storing program for determining operation appropriateness
An operation appropriateness determination system includes an authentication apparatus that identifies an operator on a basis of a feature of the operator and that outputs information for identifying the operator, a biometric sensing apparatus that obtains biological information regarding the operator and that outputs the biological information, an operation sensing apparatus that detects a load of an operation that is being performed by the operator and that outputs operation information indicating the load of the operation, a storage device, and a signal processing apparatus. |
US11407419B2 |
Central line shifting based pre-change lane path planning
A method, apparatus, and system for executing a lane change is disclosed. That an ADV is in a lane changing region for an anticipated lane change into a neighboring target lane in a first direction is determined. The first direction is either a left direction or a right direction in a direction of travel of the ADV. A reference line is moved toward the target lane in the first direction at a predetermined rate while the reference line is kept within a current lane of the ADV. A gap in traffic for the anticipated lane change is searched for. Thereafter, in response to finding the gap in traffic for the anticipated lane change, the ADV is controlled to complete the lane change into the target lane. |
US11407417B2 |
Vehicle driving assist apparatus
A vehicle driving assist apparatus includes an first calculator to calculate a degree of acceleration suppression, a controller to suppress target acceleration based on the degree of acceleration suppression, a map information storage to store road map information, an estimator to estimate a vehicle position and identify a traveling lane on the road map information, a detector to detect whether there is a crossing road ahead of the identified traveling lane, and a second calculator to calculate an azimuth angle difference between an azimuth of the crossing road where the own vehicle is about to turn and an azimuth in the traveling direction of the own vehicle. The acceleration suppression degree calculator makes a degree of acceleration suppression for suppressing the acceleration of the own vehicle higher then an azimuth angle difference becomes narrower based on the azimuth angle difference. |
US11407414B2 |
Method and apparatus for controlling vehicle driving depending on baby mode
Disclosed herein is a method of controlling a vehicle driving depending on a baby mode, including activating an apparatus for automatically controlling and limiting a speed of a vehicle, and determining a state of a car seat when the car seat is installed, correcting a speed profile of the apparatus for automatically controlling and limiting the speed of the vehicle based on the state of the car seat, determining whether the vehicle enters a turning section, when the vehicle enters the turning section, performing at least one of turning section acceleration control or turning section deceleration control based on the state of the car seat, and determining whether the vehicle passes through the turning section after performing at least one of the turning section acceleration or deceleration. |
US11407413B2 |
Techniques for monitoring powertrain cruise control propulsive torque in electrified vehicles
Powertrain propulsive torque monitoring and remedial action techniques for a cruise control mode of an electrified vehicle comprise obtaining a set of inputs indicative of a driver torque request and a state/grade of a road along which the vehicle is traveling, operating in a cruise control mode including determining a total torque request for an electrified powertrain, determining and commanding a distribution of the total torque request to the electrified powertrain, and determining the road state/grade based on at least some of the set of inputs, and monitoring the operating in the cruise control mode including determining an actual torque being generated by the electrified powertrain, determining upper and lower acceptable torque limits for the cruise control mode based on the road state/grade, and taking remedial action regarding the cruise control mode when the actual torque is outside of the upper and lower acceptable torque limits. |
US11407412B2 |
Automatic driving assist apparatus for vehicle
An automatic driving assist apparatus for a vehicle includes: a map information storage unit; an own vehicle position estimator; a route information input unit; a traveling route setting unit; a target path setting unit configured to set a target path to a center of a traveling lane; a road condition acquirer; and an automatic driving controller. The automatic driving controller further includes a branch lane determiner and a target path lateral position change amount calculator. The target path setting unit corrects the target path with a lateral position change amount calculated by the target path lateral position change amount calculator, to set a new target path. |
US11407411B2 |
Other lane monitoring device
An other lane monitoring device of the present disclosure includes an other vehicle acquisition section, a path acquisition section, a lane estimation section, and a position estimation section. The other vehicle acquisition section is configured to acquire other vehicle position information that indicates the current position of an other vehicle near the own vehicle. The path acquisition section is configured to acquire an own vehicle travel path that indicates a path along which the own vehicle has traveled. The lane estimation section is configured to use the own vehicle travel path as a basis for estimating an other lane area that is a lane where the other lane is present. The position estimation section is configured to estimate a future position of the other vehicle, assuming that the other vehicle moves along the own vehicle travel path or in the other lane area. |
US11407408B2 |
Method for performing an evasive maneuver with a utility vehicle combination, and emergency evasion system
A method for performing an evasive maneuver with a commercial vehicle-trailer combination includes ascertaining that a collision between the commercial vehicle-trailer combination and a collision object is impending. The method further includes determining an evasion trajectory by which the commercial vehicle-trailer combination can evade the collision object without coming into contact with the collision object, determining a desired steering angle based on the evasion trajectory and activating an active steering system of the commercial vehicle-trailer combination in dependence on the determined desired steering angle such that the commercial vehicle-trailer combination moves along the evasion trajectory from a starting traffic lane to a target traffic lane so as to perform the evasive maneuver. The method additionally includes determining a desired vehicle deceleration and initiating an electronic braking system of the commercial vehicle-trailer combination in dependence on the desired vehicle deceleration so as to brake the commercial vehicle-trailer combination. |
US11407407B2 |
Vehicle control device, vehicle control method, and storage medium
According to an embodiment, there is provided a vehicle control device including a recognizer configured to recognize a surrounding environment of a vehicle, a driving controller configured to perform driving control based on speed control and steering control of the vehicle on the basis of a recognition result, and an acquirer configured to acquire the remaining amount of energy of the vehicle, wherein the driving controller causes the vehicle to move from a first parking area to a second parking area where parking is possible according to traveling based on the driving control and traveling based on manual driving in a state in which the vehicle is parked or has been parked in the first parking area where the vehicle is parked according to the traveling based on the driving control and when the remaining amount of energy acquired is less than or equal to a threshold value. |
US11407406B2 |
Parking assistance device
A parking assist device according to the present invention includes a backward-direction-path calculation unit that calculates a backward-direction path for taking an own vehicle out from a target parking position B based on constraint conditions of a parking space and an own-vehicle behavior, a connection-candidate-position storage unit that sets a plurality of connection candidate positions D on the backward-direction path, a forward-direction-path calculation unit that calculates a forward-direction path leadable to one of the connection candidate positions D from a current position A of the own vehicle, and a parking-path setting unit that sets a parking path by combining the backward-direction path and the forward-direction path. |
US11407403B2 |
Vehicle control apparatus
A vehicle control apparatus includes a controller that selects an electric vehicle (EV) mode where an output clutch is disengaged and a wheel is driven by a motor, or a hybrid electric vehicle (HEV) mode where the output clutch is engaged and the wheel is driven by an engine and the motor. The controller engages the output clutch during the EV mode to adjust a gear ratio of a continuously variable transmission, and switches, in accordance with a battery state, an adjustment mode for the gear ratio, during the EV mode, between a first adjustment mode that allows the gear ratio to be adjusted in accordance with a vehicle speed, and a second adjustment mode that allows the gear ratio to be adjusted to and kept at a reference gear ratio smaller than a lowest speed gear ratio regardless of the vehicle speed. |
US11407401B2 |
Apparatus and method for starting engine of mild hybrid electric vehicle
An apparatus for starting engine of mild hybrid electric vehicle may include: an ignition switch; an ambient temperature detector; a state of charge (SOC) detector; a mild starter & generator (MHSG) including a stator and a rotor mounted inside the stator; a starter which is configured to start the engine independently of the MHSG; a converter which is configured to voltage-drop an electric power of a high voltage battery and supply it to the low voltage battery or the starter; an MHSG wheel rotating integrally with the rotor; an MHSG position detector; and a controller configured for determining a top dead center (TDC) of a predetermined cylinder based on a signal of the MHSG position detector. |
US11407399B2 |
Hybrid drive device
During shift control of a transmission mechanism, a hybrid drive device computes the amount of change in input torque (deTr) acting on the transmission mechanism and an input torque change time (t15), and controls a motor so that motor torque is changed by the amount of change in input torque (deTr), when the motor can change the amount of change in input torque (deTr), and outputs, when the motor cannot change the amount of change in input torque (deTr), an engine torque signal (Tesig1) at an engine torque change time (t14) earlier than the input torque change time (t15) at which drive power of the motor is changed when the motor can change the amount of change in input torque (deTr). |
US11407397B2 |
Brake temperature and turnaround time estimation systems and methods
A method for cooling a brake system is disclosed. In various embodiments, the method includes determining a turnaround time parameter; determining a time to cool parameter; determining a parameter difference between the time to cool parameter and the turnaround time parameter; and adjusting a flow of air directed at the brake system based on the parameter difference. |
US11407394B2 |
Method and parking brake apparatus for an autonomously drivable vehicle
A parking brake apparatus is provided for an autonomously drivable vehicle having components of a parking brake system for applying a parking brake. The parking brake apparatus comprises a first controller arranged to provide one or more control signals to be applied to components of the parking brake system to apply the parking brake in response to a signal requesting the parking brake to be applied. The parking brake apparatus also comprises a second controller arranged to provide one or more control signals to be applied to other components of the parking brake system to apply the parking brake in response to unavailability of the first controller to cause the parking brake to be applied. |
US11407392B2 |
Braking device for vehicles
The braking device for vehicles includes a reduction amount setting part for setting the amount by which to reduce the revolution of a pump motor during maintenance or reduction of controllable differential pressure so that the reduction amount decreases as the probability increases of needing to discharge the brake fluid by pumps, during a period from when a brake controller begins reducing the revolution until the lapse of prescribed time. |
US11407387B2 |
Operator interface for a vehicle wheel brake control system
An operator interface for a wheel brake control system in a vehicle includes a handle configured for coupling to a fixed reference frame in the vehicle. The handle is configured for movement relative to the fixed reference frame about a pivot axis between a neutral position and one or more input positions. One or more inertial sensors are disposed within the handle. Each sensor is configured to generate an inertial measurement signal indicative of a value of a corresponding inertial measurement associated with movement of the handle and the sensor between the neutral position and the input positions. A controller disposed within the handle is configured to generate an operator command signal responsive to the inertial measurement signals. The operator command signal is configured to cause application or release of a brake in the vehicle. |
US11407386B2 |
Vehicle turntable
Embodiments include a vehicle turntable comprising a central hub communicatively coupled to a control unit for receiving control signals; a plurality of wedge-shaped panels radially coupled to the central hub so as to form a circular surface; a plurality of wheels coupled to a number of the plurality of panels; and at least one motor configured to drive a corresponding one of the plurality of wheels and to receive the control signals from the central hub. Embodiments also include a system comprising a first turntable hub configured to control operation of a first turntable; and a control unit communicatively coupled to the first turntable hub to provide control signals to the first turntable hub. |
US11407385B2 |
Real time fuel additization
A fuel dispensing system includes that receives fuel from a fuel storage tank, and a blending system in fluid communication with the fuel dispensing unit. The blending system including a fuel conveyance device that receives the fuel from the fuel dispensing unit, and an additive conveyance device that pumps a fuel additive to be blended with the fuel based on a volumetric flow rate of the fuel, whereby the blending system provides a product mixture having a known fuel-to-fuel additive ratio. A hose and a nozzle are fluid communication with the blending system to dispense the product mixture. |
US11407382B2 |
Automated vehicle windshield wiper systems for minimizing the buildup of frozen precipitation
This disclosure details vehicle windshield wiper systems and methods for controlling windshield wipers in a manner that reduces the buildup of frozen precipitation on the vehicle windshield. In exemplary embodiments, a windshield wiper can be automatically commanded to wipe a windshield at a pre-calculated wiping interval rate when precipitation is detected on a vehicle surface, a vehicle ambient temperature is below a predefined ambient temperature threshold, and a vehicle interior temperature exceeds a predefined interior temperature threshold. |
US11407379B2 |
Vehicle occupant restraint system
A vehicle occupant restraint system is configured to, when a vehicle speed is higher than or equal to a vehicle speed threshold, a steering angle velocity is higher than or equal to a steering angle velocity threshold set for each vehicle speed, and an estimated lateral acceleration is higher than or equal to an acceleration threshold, drive a retractor motor. The steering angle velocity threshold is as a condition to drive the retractor motor. Therefore, by setting an appropriate steering angle velocity threshold according to an amount of movement of an occupant with inertia in a vehicle width direction, the vehicle occupant restraint system is able to take up a webbing when the occupant is estimated to move with inertia by a relatively large amount in the vehicle width direction. The amount of movement with inertia varies for each vehicle speed even at the same steering angle velocity. |
US11407374B2 |
Processing device, processing method, and program for at least one of controlling a traveling state of a movable object depending on use information of a first training device and restricting use states of one or more training devices depending on the traveling state of the movable object
A processing device includes a control unit configured to execute identifying a first training device that is of one or more training devices equipped in a movable object for providing a training opportunity to a passenger and that is used by the passenger, and at least one process of controlling a traveling state of the movable object depending on a content of a training using the first training device and restricting use states of the one or more training devices depending on the traveling state of the movable object. |
US11407373B2 |
Occupant protection device
An occupant protection device for a vehicle includes a collision predictor, a main airbag, and a deployment controller. The collision predictor is configured to predict a collision of the vehicle. The main airbag is configured to deploy toward an occupant from a front of the vehicle when a collision of the vehicle is predicted by the collision predictor. The main airbag includes a first deployment part, an arm-push-away deployment part, and a second deployment part. The controller is configured to cause the main airbag to deploy toward the occupant when a collision of the vehicle is predicted by the collision predictor. The controller is configured to, when a collision of the vehicle is predicted by the collision predictor, cause the first deployment part to deploy, subsequently cause the arm-push-away deployment part to deploy to push an arm of the occupant away, and thereafter, cause the second deployment part to deploy. |
US11407367B2 |
Soundproof body and silencer for motor vehicles
A soundproof body is formed by a two-layer lamination structure of a felt layer and a film layer. Some of plural fibers constructing the felt layer are formed to be thicker than the remaining fibers. |
US11407366B2 |
Bracket for a pillar assembly
A bracket for a vehicle includes a first surface that defines support ribs and a second surface. A cantilevered end defines an attachment aperture. A retention feature is coupled to an upper edge of the cantilevered end and defines a retention notch. A central portion defines an arcuate notch and a fastening aperture. An attachment end includes a coupling feature that extends outwardly from the first surface. |
US11407363B2 |
Method for calculating a tow hitch position
A method for calculating a tow hitch position of a trailer is presented. A first and a second image of the trailer is captured and a trailer rotation and translation relative to a known zero pose of the trailer based on the captured first and second images is calculated. The rotation axes of the trailer in the first and second image is calculated based on the calculated trailer rotations and translations. An intersection of the first and second rotation axis is calculated to determine a ray to the tow hitch position. The ray to the tow hitch position and a geometrical condition are used to calculate the tow hitch position. |
US11407361B2 |
Side folding tow behind motorcycle transporter
A motorcycle transporter includes a main frame comprising a hitch connection to couple to a tow hitch on a tow vehicle. A front tire carrier assembly is coupled to the main frame through a lift and comprises a rear tilting cradle hingedly coupled to a forward stationary cradle, each formed into a channel shaped to receive a motorcycle tire. The stationary cradle is coupled to the lift, a cradle side rail latch housing and a corresponding side rail latch coupled to the cradles to lock the rear tilting cradle in an open position and in a closed position. The open position enables the motorcycle tire to roll into the channel at ground level. The closed position restrains the motorcycle tire in the channel. The lift is arranged to raise the cradle from the ground level. |
US11407359B2 |
Method and system of displaying multimedia content on glass window of vehicle
Disclosed is a method of displaying content on a glass window of a vehicle, including capturing sight information of surrounding scenery of the vehicle during a first time period, by using at least one first image capturing device, identifying a request for displaying content related to the sight information from a user during a second time period after the first time period, and displaying the content related to the sight information on the glass window of the vehicle based on the request. |
US11407357B2 |
Absolute acceleration sensor for use within moving vehicles
A communication system for a vehicle comprises a mechanism for sensing a braking of the vehicle and a control device for sending a signal to a headlight activation circuit to modulate the vehicle's headlights based upon the braking of the vehicle. In particular, a headlight of the vehicle is able to be modulated based upon an application of one or both of a front brake and a rear brake. The headlight activation circuit is able to modulate the headlight between an on position and an off position or modulate the headlight between a high beam position and a low beam position. Consequently, the vehicle is better seen as it approaches likely congestion areas such as intersections and slowing or stopped traffic and attempts to enter traffic. |
US11407353B2 |
Method for adjusting light distribution pattern of vehicle lamp and electronic device thereof
An electronic device may include: a camera module; a plurality of light source devices; and a processor operatively coupled to the camera module and the plurality of light source devices. The processor may detect a forward vehicle based on an image acquired through the camera module while a vehicle travels, identify a distance between the vehicle and the forward vehicle, and adjust light distribution patterns of the plurality of light source devices based on the identified distance. |
US11407351B2 |
Loading arm assembly for a load-handling vehicle for loading ISO containers and for loading transportation containers having a hook
A loading arm assembly for a load-handling vehicle has a main arm and an auxiliary arm. The loading arm assembly is configured for unloading and loading ISO containers and for unloading and loading transportation containers having a hook. The loading arm assembly is improved in that a crossbeam having two corner grippers and furthermore, separately therefrom, a telescopic gripping hook is disposed on the auxiliary arm. |
US11407349B2 |
Bus occupancy check safety apparatus kit
A bus occupancy check safety apparatus kit for confirming seats are not occupied includes a seat occupancy cover belt system comprising a rear mount configured to be coupled to a rear of a bus. A belt has a back end coupled to the rear mount and a front end coupled to a male buckle. A front mount is coupled to a front of the bus and to a female buckle that is selectively engageable with the male buckle. The belt is drawn across a plurality of seats within the bus to engage the male buckle with the female buckle. A seat occupancy window indicator comprises a suction cup, a pull nub, and a sign having a lettered side displaying a message. |
US11407347B2 |
Multiple stage headrest
A headrest may be fixed relative to a seat or a bank of seats in a vehicle and can provide multiple stages of deformation in response to a collision event. The headrest can include a resilient member that deforms in response to a first force caused by the collision event. The headrest can also include a frame that deforms in a first manner in response to a second force greater than the first force and in a second manner in response to a third force greater than the second force. Such a headrest can provide improved impact mitigation for occupants, regardless of height and/or weight such that occupants ranging from the 5th to 95th percentile in height and/or weight are afforded similar impact mitigation despite a fixed headrest structure. In some examples, multiple such headrests may be conjoined. |
US11407344B2 |
Work vehicle having driver's seat
A work vehicle includes a driver's seat attached to a seat base, a support shaft attached to the seat base and extending in a vehicle body transverse direction, the support shaft pivotably connecting the seat base with the vehicle body frame, and an isolator mounted on the support shaft to absorb only vibration in a vehicle body front/rear direction. |
US11407336B2 |
Stamped splined locking mechanism for rotating automotive seat bracket
A vehicle seat rotates in response to activation of an electric motor. The electric motor is part of a non-back-drivable mechanism such that it acts to lock the seat in position. The seat mechanism is assembled from stamped components for efficient manufacturing. A bracket includes integrally formed gear teeth which mesh with gear teeth driven by the electric motor. The bracket is held between two stamped parts using four-point angular contact ball bearings. The races of the ball bearings are stamped into the respective stamped parts. |
US11407335B2 |
Vehicle seat
Provided is a vehicle seat that is rotatable relative to a vehicle body and can prevent a collision between an object located around a seat body and an occupant by airbags. A vehicle seat includes: a seat body (6) supported by a vehicle body (2b) so as to be rotatable around a substantially vertical axis; a pair of airbags (17) provided on either lateral side edge of the seat body and configured to deploy to respective lateral sides of an occupant seated on the seat body; a rotation angle detecting device (15) provided on the seat body and configured to detect a rotation angle of the seat body relative to the vehicle body; and a control device (22) configured to control deploying operation of the respective airbags independently of each other. The deploying operation includes a deploying amount and/or a deploying timing. The control device is configured to individually control the deploying operation of the pair of airbags according to the rotation angle detected by the rotation angle detecting device. |
US11407331B2 |
Battery heating system
In a battery heating system an inverter includes a first-phase bridge arm, a second-phase bridge arm and a third-phase bridge arm connected in parallel, each of a upper bridge arm and a lower bridge arm is provided with a switch module, the switch module is connected in parallel with a buffer module; and a motor controller in the inverter is provided for providing driving signals to the switch module of a target upper bridge arm and the switch module of a target lower bridge arm to control the switch module of the upper bridge arm of any bridge arm among the three phases of bridge arms and the switch module of the lower bridge arm of at least one bridge arm among the bridge arms except the bridge arm where the switch module of the target upper bridge arm is located to be periodically turned on and off. |
US11407325B2 |
Systems and methods for integrating on-premises electric appliances with vehicle-to-grid electric vehicles
An energy management system includes a local power grid configured to route electricity, the local power grid configured to receive electricity from a municipal power grid of a utility service provider; an electric appliance electrically coupled to the local power grid, the electric appliance configured to receive electricity from the local power grid for operating according to an energy usage state; an electric vehicle electrically coupleable to the local power grid, the electric vehicle configured to exchange electricity with the local power grid; and a system server communicatively coupled to the electric appliance and the electric vehicle. The system server configured to: receive utility related data, appliance related data, and vehicle related data, determine, based on the received data, a vehicle-to-grid energy cost and a utility energy cost, and control the electric vehicle to discharge electric energy to the local power grid for operating the electric appliance, based on a comparison of the vehicle-to-grid energy cost with the utility energy cost for operating the electric appliance according to the energy usage state. |
US11407319B2 |
Method and apparatus for charging an energy store
An energy store (14a) has at least three energy storage sections (u, v, w) and at least two switching elements. Each energy storage sections (u, v, w) has multiple energy storage modules and each energy storage module has at least one energy storage element that receives and stores energy from an energy source (12). The energy store (14a) is connected to a first coil (50) so that a voltage induced in the first coil (50) is used to charge the energy storage elements. The energy store (14a) is matched to properties of the voltage provided by the first coil (50) by switching the switching elements. As a result, the energy storage modules of an energy storage section (u, v, w) are connected in parallel and/or in series with one another and/or at least one energy storage module of at least one energy storage section (u, v, w) is bypassed. |
US11407318B2 |
Method and apparatus for controlling wireless power transfer
A method for controlling wireless power transfer (WPT), performed by an electric vehicle (EV) device receiving power from a supply device is provided. The method includes checking service details regarding at least one method for fine positioning and pairing between the supply device and the EV device and selecting a service. Fine positioning is performed with the supply device according to a pairing method associated with the selected service. Additionally, LF pairing is performed based on the selected service; an initial alignment check is performed using pre-charging power transmission; and LPE pairing is performed based on the selected service and a result of the initial alignment check. |
US11407315B2 |
Method for determining a load distribution, control unit, powertrain and motor vehicle
A method for determining a load distribution in a powertrain of a motor vehicle, whereby the powertrain has at least two drive machines, whereby the first drive machine is provided for a front-wheel drive and the second drive machine is provided for a rear-wheel drive, whereby the method comprises: determining a load distribution characteristic map that is based on a first efficiency characteristic map of the first drive machine and on a second efficiency characteristic map of the second drive machine. |
US11407314B2 |
Brake system
A brake system includes: a friction brake mechanism; a regenerative brake mechanism; and an electronic control unit. The electronic control unit is configured to obtain a target regenerative braking force. The electronic control unit is configured to perform replacement control between the friction brake mechanism and the regenerative brake mechanism when a predetermined replacement condition is satisfied. The replacement control is control in which a shortfall of the required total braking force, which is caused by a decrease in the regenerative braking force, is covered by increasing the front wheel friction braking force and the rear wheel friction braking force while satisfying a set relationship between the front wheel friction braking force and the rear wheel friction braking force or between an increase gradient of the front wheel friction braking force and an increase gradient of the rear wheel friction braking force. |
US11407312B2 |
Charging cable for a motor vehicle which can be operated by electricity
A charging cable for a motor vehicle can be operated by electricity having a filter device. The charging cable includes a first conductor and a second conductor configured to transfer a current, a safety ground line, and a signal line configured to transfer charging information relating to a charging process. The filter device includes a core around which the first and second conductors and the safety ground line are wound, and the signal line is wound around the core. |
US11407309B2 |
Vehicle controlling apparatus and vehicle having the same
Disclosed is a vehicle controlling apparatus for controlling a vehicle having a display. The vehicle controlling apparatus includes: a communication unit configured to communicate with the display; and a processor configured to set at least one region among an entire region of the display as a display region, based on a sight line range changed according to a position of a passenger who got on the vehicle, and configured to control the communication unit so that visual information is displayed on the display region. |
US11407307B2 |
Drive axle system having multiple electric motors
A drive axle system having at least one differential assembly, a first electric motor, and a second electric motor. The first electric motor and the second electric motor may be selectively connectable to the differential assembly. The first electric motor, the second electric motor, or both may provide torque to the differential assembly. |
US11407303B2 |
Control device
A control device with an electronic control unit that is configured to perform specific supply control, the specific supply control driving at least one of the rotating electrical machine and the internal combustion engine in a neutral state, and supplying hydraulic pressure to an engagement operating part of a target engagement device with at least one of the rotating electrical machine and the internal combustion engine being driven, the automatic transmission not transmitting power in the neutral state, and the target engagement device being one of the plurality of transmission engagement devices. |
US11407302B2 |
Torque transfer assembly and vehicle including the same
A torque transfer assembly includes an engine starter, an electric machine, a torque converter, and a disconnect clutch further defined as a mechanical clutch. The vehicle includes an internal combustion engine including an output shaft, and a transmission. The engine starter is adapted to be rotatably coupled to the output shaft for rotating the output shaft to start the internal combustion engine. The electric machine is adapted to be rotatably coupled to the transmission for delivering rotational torque to the transmission. The torque converter is rotatably coupled to the electric machine and adapted to be rotatably coupled to the transmission. The mechanical clutch is adapted to be rotatably coupled to the output shaft and the torque converter. The mechanical clutch is adapted to selectively rotatably couple the output shaft to the torque converter and is adapted to selectively rotatably decouple the output shaft from the torque converter. |
US11407297B2 |
Impact energy absorbing carrier and impact energy absorbing member
The invention provides an impact energy absorbing carrier including a frame, a carrier, and multiple impact energy absorbing units. Each of the impact energy absorbing units includes a first link, a second link, and an impact energy absorbing member. The first link and the second link are respectively fixed to the frame and the carrier. The impact energy absorbing member includes a periphery part and two protrusion parts. The periphery part includes a first side portion and a second side portion located opposite to each other. The first side portion of the periphery part are respectively and pivotably disposed on the first link and the second link. The periphery part surrounds the protrusion parts, the protrusion parts are respectively connected to the first side portion and the second side portion of the periphery part, and a first buffering space is located between the protrusion parts. |
US11407289B2 |
Method and apparatus for windshield heating using carbon nanotube heating pad
Methods and apparatus are provided for heating a vehicle window to remove ice and condensation using a carbon nanotube heating pad. The apparatus includes a user interface operative to receive a user request, a vehicle windshield, a heating pad wherein the heating pad includes a carbon nanotube heating element and a reflective surface and is oriented such that the carbon nanotube heating element is directed towards the windshield, a power supply operative to supply power to the carbon nanotube heating element in response to a control signal, and a processor operative to generate the control signal in response to the user request. |
US11407285B2 |
Vehicle cooling mechanism
A vehicle cooling mechanism includes a first radiator configured to cool a battery of a vehicle, a second radiator configured to cool a power conversion device that converts electric power supplied from the battery and electric power supplied to the battery, and an air guide duct portion configured to guide outside air from an opening portion provided in a front end portion of the vehicle to the first radiator and the second radiator. The first radiator is arranged above the second radiator. At least a part of the second radiator is arranged so as to overlap the opening portion as viewed from a front side of the vehicle. An upper end portion of the second radiator is positioned above an upper end portion of the opening portion. A lower end portion of the second radiator is positioned below the upper end portion of the opening portion. |
US11407283B2 |
Cab heating systems and methods for vehicles
A cab heating system for a vehicle comprising a turbine engine, a heat exchanger, and a duct. The turbine engine generates exhaust containing waste heat. The heat exchanger comprises a first portion, a second portion, and first and second lines for carrying auxiliary working fluid between the first and second portions. The duct is operatively connected to carry exhaust from the turbine engine to the first portion of the heat exchanger. The first portion of the heat exchanger transfers waste heat of the exhaust generated by the turbine engine to the auxiliary working fluid. The first line carries the auxiliary working fluid to the second portion of the heat exchanger. The heat exchanger extracts heat from the auxiliary working fluid. The second line carries the auxiliary working fluid to the first portion of the heat exchanger. |
US11407280B1 |
Ultra-low-cost coolant heating apparatus for electric vehicle applications
An ultra low cost electric vehicle heating apparatus, components thereof, and related method are herein described. A driver circuit operates a switching device at an intermediate state between fully-turned-off and fully-turned-on, in a high power dissipation heating mode, to efficiently produce heat energy for heating a passenger compartment, or energy storage system, of an electric vehicle. The driver circuit operates the switching device to have a fully-turned-off state and a fully-turned-on state in a main function mode for a traction inverter or an energy storage system charger of the electric vehicle. The driver circuit is operable to cycle the heating mode and the main function mode for combining such heating and such main function operation of the traction inverter, or the charger, without compromising the operation of the traction motor, or charger, while simultaneously eliminating many of the expensive resistive heating components in use by practitioners of the art. |
US11407278B2 |
Vehicle cabin thermal management system
A vehicle cabin thermal management system includes a first heat exchange system adapted to operate primarily based upon a convective mode of heat transfer within a vehicle cabin, a second heat exchange system adapted to operate primary based upon a non-convective mode of heat transfer within the vehicle cabin, and a controller in communication with the first heat exchange system and the second heat exchange system, wherein the controller controls a thermal output of the second heat exchange system, and wherein the controller controls the first heat exchange system to reduce the operating level of the first heat exchange system in response to the controller operating the second heat exchange system. |
US11407275B2 |
Heat flow management device and method for operating a heat flow management device
Heat flow management device for motor vehicles has a refrigerant circulation, a power train coolant circulation and a heating line heat carrier circulation. The refrigerant circulation includes a compressor, an indirect condenser, an expansion element, an ambient heat exchanger, an evaporator and a chiller. The power train coolant circulation includes a coolant pump, the chiller, an electric motor heat exchanger and a power train coolant radiator, wherein the heating line heat carrier circulation comprises a coolant pump, the indirect condenser and a heating heat exchanger, wherein the refrigerant circulation and the power train coolant circulation are directly thermally coupled with one another across the chiller. Refrigerant circulation and heating line heat carrier circulation are directly thermally coupled with one another across the indirect condenser. Power train coolant circulation and the heating line heat carrier circulation are only indirectly thermally coupled with one another across the refrigerant circulation. |
US11407274B2 |
Accumulator pressure drop regulation system for a heat pump
A refrigeration circuit for a vehicle system includes a compressor, an evaporator, an accumulator, an inlet tube, an outlet tube, and a bypass valve. The inlet tube is configured to deliver refrigerant from the evaporator to the accumulator. The outlet tube is configured to deliver refrigerant from the accumulator to the compressor. The bypass valve is in fluid communication with the inlet and outlet tubes. The bypass valve has an open position and a closed position. The bypass valve is configured to direct refrigerant flow from the inlet tube to the outlet tube to bypass the accumulator when in the open position. The bypass valve is configured to restrict refrigerant from flowing from the inlet tube to the outlet tube when in the closed position. |
US11407268B2 |
Variable tracking active suspension system
An active suspension system for a sprung mass that is supported and movable relative to an unsprung mass. The active suspension system has a suspension that comprises an electromagnetic actuator that is adapted to produce an arbitrary force on the sprung mass that is independent of the position, velocity and acceleration of the sprung mass, a control system that provides control signals that cause the suspension to exert force on the sprung mass, to control the position of the sprung mass relative to the unsprung mass, wherein the control system implements a control algorithm with one or more constants, and a user interface that is operable to cause a change of one or more of the control algorithm constants so as to vary how closely motion of the sprung mass follows motion of the unsprung mass. |
US11407267B2 |
Silencer for leaf spring for commercial vehicle
A silencer for a leaf spring for a commercial vehicle is provided. The silencer includes an upper rubber body having defined therein a fitting hole into which a second leaf spring is press-fitted, with a top surface of the upper rubber body serving as a contact surface in contact with a first leaf spring, and a lower rubber body having defined therein an accommodation space, with a first buffering protrusion being provided on a bottom surface of the lower rubber body such that a third leaf spring is able to be in contact with the first buffering protrusion. |
US11407264B2 |
Hitch for an agricultural vehicle
A first assembly combinable to the heavy equipment and a second assembly pivotally attached to the first assembly for rotation about a first axis and configured for pivotal attachment to the vehicle for rotation about a second axis. A tow rod extending from the first assembly with a third axis extending therethrough and combinable to the heavy equipment and configured for rotation with respect to the heavy equipment about the third axis. |
US11407263B1 |
Swivel trailer
A swivel trailer is described that can include a swivel hitch and swivel axle configuration which prevents a vehicle and trailer from jackknifing. |
US11407260B2 |
Ball and socket articulating TPM sensor
A tire monitoring apparatus comprises a sensor housing having a connection part integrated with the sensor housing, the connection part having an elongated opening and a corresponding mounting feature in a wheel rim, wherein a screw extends through the elongated opening and connects with the corresponding mounting feature in the wheel rim, thereby when the screw is not tightened fully, the sensor housing can be rotated with respect to the corresponding mounting feature in the wheel rim, and when the screw is tightened fully, the sensor housing is secured in place and does not rotate with respect to the corresponding mounting feature in the wheel rim. |
US11407259B2 |
Method of monitoring the pressure of an aircraft tire
A method of monitoring the pressure of a tire of an aircraft, the method including: taking two or more pressure readings from the tire at different times; calculating an estimated deflation rate based on the pressure readings; and calculating a time for the tire to deflate to a reference pressure level based on the estimated deflation rate. Two or more temperature readings are each associated with one of the pressure readings, and the estimated deflation rate is calculated by normalising each pressure reading based on its associated temperature reading and a common reference temperature to obtain a temperature-normalised pressure reading, and calculating the estimated deflation rate based on the temperature-normalised pressure readings. The estimated deflation rate is compared with a threshold, and a warning provided if the estimated deflation rate exceeds the threshold. |
US11407258B2 |
Pneumatic tire
Provided is a pneumatic tire with a side pattern including a ridge pattern region provided with first ridges extending continuously in one direction at an interval; and a marking display region bordering and being surrounded by the ridge pattern region, the marking display region displaying markings including one or more of a letter, a number, a symbol, and/or a figure. The marking display region includes: a bordering ridge that borders an outer edge of the markings; and second ridges provided in an inner region of the markings and extending continuously in one direction at an interval from each other. Ends of the first ridges and the second ridges are connected to the bordering ridge, and apexes of the first ridges and the second ridges are flush with and connected to an apex of the bordering ridge. |
US11407257B2 |
Pneumatic tire
A tread pattern of a pneumatic tire includes one center continuous land portion and two intermediate continuous land portions that are divided by four circumferential main grooves and that are not provided with lug grooves. Edges on both sides of one center main groove include groove chamfered portions having a chamfered width changing in the circumferential direction in a zigzag shape. In the regions of the intermediate continuous land portions, first sipes extending inward in the lateral direction from shoulder main grooves of the main grooves, which are positioned on outer sides in the lateral direction, are provided. The first sipes each include a sipe main body portion having a constant distance between sipe wall surfaces on a sipe bottom side and a sipe chamfered portion inclined so that the sipe wall surfaces are open toward the tread surface. |
US11407256B2 |
Tyre
A tyre includes a tread portion including a crown land portion defined between two main grooves extending continuously in a tyre circumferential direction. The crown land portion is provided with crown lateral grooves traversing the crown land portion. Each of the crown lateral grooves, in a cross-sectional view perpendicular to its longitudinal direction, includes a sipe portion having a width equal to or less than 1.5 mm, and a main portion connected to the sipe portion and opening at a ground contact surface of the crown land portion. The main portion has a width enlarging from the sipe portion. The main portion has a depth smaller than depths of the main grooves. The sipe portion has a first wall extending in a tyre radial direction so as to be continuous with a first wall of the main portion to form a single groove wall together. |
US11407254B2 |
Non-pneumatic tyre with an improved cavity aperture
A tire comprising a plurality of cavities formed on each of the first and second tire sidewalls. The cavities are extending longitudinally from a cavity opening up to a predetermined distance in the radial middle portion, wherein each cavity comprises a bottom surface and at least one cavity sidewall surface extending from the bottom surface to the cavity opening, said bottom surface and at least one sidewall surface defining an unpressurised cavity space. At least one of the tire cavities comprises at least one structural element extending outwardly from at least one of the cavity surfaces. |
US11407252B2 |
Trim on an automobile wheel rim
A decorative trim panel on an automobile rim composed of at least one plate-shaped trim element that at least partially covers the visible side of the automobile rim, which can be secured by retaining means on the spokes of the rim, wherein a fastening plate bears on the back surface of the at least one spoke in a load transferring manner, and can be attached to the trim element in each case via retaining connections. |
US11407249B2 |
Tab press and method of marking indicia on tab stock
A method of marking indicia on tab stock used to provide tabs for use with can ends. The method comprises providing the tab stock to a tab press comprising a punch and a die. The punch comprises a set of raised features and the die comprises a respective set of recessed features such that the features cooperate to deboss said indicia on regions of the tab stock within tab forming areas that face outwardly when the tabs are attached to a tab end. The features are such that, when the press is fully closed, the spacing between at least part of each of the raised features and at least part of each of the respective recessed features is less than the thickness of the tab stock in said regions within tab forming areas. |
US11407246B2 |
Embedded variable line patterns
A system is capable of generating identifications that include distinctive line patterns corresponding to different portions of secure customer information. In some implementations, data indicating one or more linear patterns and data indicating customer information to be embedded within an identification document is obtained. Respective subsets of the customer information are assigned to each of the one or more linear patterns. A photographic image to be included within the identification document is then modified based at least on generating a portion of the photographic image that is composed of at least one of the one or more linear patterns. The modified photographic image is then disposed on an identification document to yield embedded customer information. |
US11407245B1 |
Sublimation systems and related methods
A sublimation device includes a first heater and a second heater. The first heater includes a proximal end, a distal end, and an inner surface. The distal end is disposed opposite the proximal end. The inner surface extends between the proximal end and the distal end and at least partially forms a cavity. The second heater is disposed proximate the distal end of the first heater. |
US11407243B2 |
Image forming system and method to control an image forming system
An image forming system, having a recording head, a sheet conveyer, an inverting mechanism, and a controller, is provided. The sheet conveyer conveys a sheet in a sheet-conveying direction. The sheet is nipped at nipping points located at positions upstream and downstream in the sheet-conveying direction with respect to a discharging position. The inverting mechanism inverts the sheet from a first side to the second side. The controller determines an initial arrangement of the sheet in the sheet conveyer where image-forming on the second side starts, and controls a length of a period between time, when image-forming on the first side of the sheet in the posture with the first side facing the recording sheet is completed, and time, when the image-forming on the second side of the sheet inverted and refed to the sheet conveyer starts, based on the determined initial arrangement of the sheet in the sheet conveyer. |
US11407237B2 |
Light-irradiating device and printing device
A light-irradiating device according to the disclosure includes: a light-emitting element; a housing in which the light-emitting element is disposed, the housing including a light-irradiating surface provided with an irradiating opening which is capable of allowing light from the light-emitting element to pass therethrough; a flow path configured to supply gas, the flow path including an end located near the irradiating opening of the light-irradiating surface of the housing; and a discharging port configured to discharge the gas, the discharging port being disposed at the end of the flow path, the discharging port including a plurality of first openings arranged in a width direction of the irradiating opening in correspondence with the irradiating opening, and a second opening positioned in correspondence with each end in the width direction of the irradiating opening. This makes it possible to reduce uneven distribution of discharged gas improve the reliability of a curing reaction. |
US11407234B2 |
Printer
A printer includes a treatment liquid applier configured to apply a treatment liquid onto a sheet, a printing device configured to print on the sheet onto which the treatment liquid has been applied, a heater configured to heat the treatment liquid in the treatment liquid applier, and circuitry configured to control the heater according to a printing condition to print on the sheet. |
US11407232B2 |
Method of printing and printing apparatus
A method comprises printing an image using a printhead cartridge including a number of dies, each die comprising a nozzle array, the printing comprising: determining a drop parameter of fluid drops ejected from nozzles of the nozzle array of at least one die; comparing the drop parameter to a threshold value; and determining an image characteristic of an image to be printed; and if the image characteristic meets a defined criterion and if the drop parameter exceeds the threshold value, applying a second print mask for printing the image; and if the image characteristic does not meet the defined criterion or if the drop parameter does not exceed the threshold value, applying a first print mask for printing the image, wherein the second print mask uses less nozzles of the nozzle arrays than the first print mask. |
US11407231B2 |
Image processing method
A surface tension difference between a first ink and a third ink is smaller than a surface tension difference between the first ink and a second ink. A first gradation value for the first ink is quantized to generate a first quantized value, a second gradation value for the second ink is quantized to generate a second quantized value, and a third gradation value for the third ink is quantized to generate a third quantized value. The above quantization processing is performed such that, in a predetermined pixel region, the number of pixels for each of which the second quantized value and the third quantized value both indicate printing is greater than the number of pixels for each of which the first quantized value and the third quantized value both indicate printing. |
US11407229B2 |
Logic circuitry package
A logic circuitry package for a replaceable print apparatus component includes an interface to communicate with a print apparatus logic circuit, and a logic circuit having a communication address to communicate with the print apparatus logic circuit. The logic circuit is configured to detect, via the interface, communications that include an other communication address. The logic circuit is configured to respond, via the interface, to a command series directed to the logic circuit that include the communication address of the logic circuit, based on the detected communications. |
US11407228B2 |
Logic circuitry package
A logic circuitry package for a replaceable print apparatus component includes an I2C interface to communicate with a print apparatus logic circuit and at least one logic circuit. The at least one logic circuit is configured to respond to communications over the I2C interface that are directed to an initial or reconfigured I2C address. The at least one logic circuit is configured to receive, via the I2C interface, a write command to a first memory address of the logic circuit to initiate a first function of the logic circuit. The at least one logic circuit is configured to generate first data in response to the first function. The at least one logic circuit is configured to receive, via the I2C interface, a first read command to a second memory address of the logic circuit. The at least one logic circuit is configured to transmit, via the I2C interface, the first data in response to the first read command to the second memory address. |
US11407226B2 |
Image recording method and ink set
An image recording method is provided. The image recording method includes the steps of: applying a treatment liquid containing a pore forming material onto a recording medium to form a porous layer; and applying a metallic ink containing a metallic pigment onto the porous layer. A surface tension of the metallic ink at 23° C. is equal to or greater than a surface tension of the treatment liquid at 23° C. The surface tension of the metallic ink at 23° C. is 19 mN/m or more and 28 mN/m or less. |
US11407221B2 |
Maintaining a print quality parameter in a printer
A printer includes a print head to print a pixel by ejecting drops of a printing fluid from the print head, and a controller. The controller monitors a drop volume of the printing fluid ejected by the print head. When the drop volume is below a threshold, the controller controls the print head in accordance with a first print mode to increase the frequency of ejecting drops of the printing fluid within the pixel print time with a decrease in the drop volume that maintains a print quality parameter. The controller changes to a second print mode to increase the pixel print time that maintains the print quality parameter. |
US11407219B2 |
Liquid discharge apparatus
A liquid discharge apparatus includes a head to discharge a liquid containing a solvent from a discharge port toward an object, a concentration detector to detect a vapor concentration of the solvent, and circuitry to causes the head to discharge the liquid from the discharge port while moving the discharge port of the head in a movement direction perpendicular to a discharge direction to discharge the liquid. When the vaper concentration is equal to or higher than a first threshold, the circuitry stops moving the head in the movement direction and causes the head to stop discharging the liquid from the discharge port. When the vaper concentration is less than a second threshold, the circuitry resumes moving the head in the movement direction from a stop position where the head stops moving in the movement direction and causes the head to resume discharging the liquid from the discharge port. |
US11407218B2 |
Identifying random bits in control data packets
A fluid ejection controller interface includes input logic to receive control data packets and a first clock signal, each control data packet including a set of primitive data bits and a set of random bits, wherein the input logic identifies the random bits in the received control data packets to facilitate the creation of modified control data packets. The fluid ejection controller interface includes a clock signal generator to generate a second clock signal that is different than the first clock signal, and output logic to receive the modified control data packets, and output the modified control data packets to a fluid ejection controller of a fluid ejection device based on the second clock signal. |
US11407211B1 |
Fabrication of shaped voids
In some examples, a method includes forming a material layer on a substrate, partially polymerizing a component of the material layer, to form fluid-filled droplets within a partially polymerized matrix, deforming the material layer to form anisotropic fluid-filled droplets, and further polymerizing the partially polymerized matrix to form an anisotropic voided polymer, including anisotropic voids in a polymer matrix. The anisotropic voids may include anisotropic nanovoids. Example methods may further include depositing electrodes on the anisotropic voided polymer so that at least a portion of the anisotropic voided polymer is located between the electrodes. Examples may include forming electroactive elements including an anisotropic nanovoided polymer, and devices (such as sensors and/or actuators) including electroactive elements. |
US11407204B2 |
Laminated glazing with an electrically controllable device and manufacture
A laminated glazing incorporates an electrically controllable device and the manufacture thereof including an operation of preassembly with a thin plastic strip. |
US11407201B2 |
Composite member
A composite member (1) satisfies the following expressions. X/(E×|CTE(B)−CTE(A)|)≥50, X/(E×|CTE(B)−CTE(C)|)≥50, Y/|CTE(B)−CTE(A)|×L(BA)≤50, and Y/|CTE(B)−CTE(C)|×L(BC)≥50. X: shear bond strength (MPa) between the heat dissipating base substrate and heat generating member, Y: fracture elongation of the thermoconductive insulating adhesive film, E: modulus of elasticity (MPa) of the thermoconductive insulating adhesive film, CTE(A): linear expansion coefficient (° C.−1) of the heat dissipating base substrate, CTE(B): linear expansion coefficient (° C.−1) of the thermoconductive insulating adhesive film, CTE(C): linear expansion coefficient (° C.−1) of the material of the surface of the heat generating member in contact with the thermoconductive insulating adhesive film, L(BA): initial contact length (m) between the thermoconductive insulating adhesive film and the heat dissipating base substrate, and L(BC): initial contact length (m) between the thermoconductive insulating adhesive film and the heat generating member. |
US11407198B2 |
Roofing underlay, particularly for using as roof cladding underlay and/or roof lining membrane
The invention relates to a roofing underlay (1), especially one intended for use as roof cladding underlay and/or roof lining membrane, having at least one outer nonwoven layer (2), at least one inner nonwoven layer (3) and at least one microporous membrane layer (4) based on at least one polyolefin plastic, wherein the membrane layer (4) is arranged between the outer nonwoven layer (2) and the inner nonwoven layer. According to the invention, it is provided that at least one further microporous membrane layer (5) based on a polyolefin plastic is provided between the outer nonwoven layer (2) and the inner nonwoven layer and the further membrane layer (5) is separated from the membrane layer (4) by a separating layer (6), wherein the separating layer (6) is water-permeable and/or embodied as a structure made of fibers, especially nonwoven. |
US11407196B2 |
Article with microstructured layer
Article comprising a first, microstructured layer comprising a first material, and having first and second opposed major surfaces, the first major surface being a microstructured surface, and the microstructured surface having peaks and valleys, wherein the peaks are microstructural features each having a height defined by the distance between the peak of the respective microstructural feature and an adjacent valley; and a second layer comprising at least one of a crosslinkable or crosslinked composition, wherein at least a portion of the second major surface of the second layer is directly attached to at least a portion of the first major surface of the first, microstructured layer. Articles described herein are useful, for example, for optical film applications. For example. An article including a regular prismatic microstructured pattern can act as a totally internal reflecting film for use as a brightness enchancement film; an article including a corner-cube prismatic microstructured pattern can act as a retroreflecting film or element for use as reflecting film when combined with a back reflector; and an article including a prismatic microstructured pattern can act as an optical turning film or element for use in an optical display. |
US11407191B2 |
Method for the manufacture of a shoe sole, shoe sole, and shoe with pre-manufactured TPU article
Described are a method for the manufacture of a shoe sole, the sole manufactured by the method, and a shoe including the sole. The method includes loading a pre-manufactured article comprising thermoplastic polyurethane (TPU) material into a mold; loading pellets of an expanded thermoplastic polyurethane (eTPU) material into said mold; and connecting the pellets with each other and to the pre-manufactured TPU article by providing an interconnecting medium, wherein the material of the pre-manufactured TPU article either comprises an additive to increase the viscosity of the material of the pre-manufactured TPU article, or has been annealed. |
US11407189B2 |
Additively-manufactured corner cube substrate
Techniques are disclosed to enable manufacture of open-air corner-cube retroreflectors having a corner-cube cavity. The techniques involve additively forming a substrate by way of additive manufacturing technologies such as three-dimensional printing technologies. The techniques further involve optionally machining the additively formed surface of the substrate and replicating a reflective surface in the corner-cube cavity using a master that is coated with a reflective material. An adhesive is applied to the corner-cube cavity so that when the adhesive cures and the master is withdrawn from the corner-cube cavity, the reflective surface adheres to the adhesive and remains an integral part of the retroreflector. |
US11407187B2 |
Continuous channel resin transfer molding with rapid cycle time
A process for resin transfer molding (RTM) with injection and overflowing of a resin through one or more troughs is provided that includes the injection of resin into a plurality of injection ports feeding the one or more troughs and overflowing the resin in into a mold. The temperature and pressure are controlled as applied to the mold. The injection ports are activated for injecting the resin in any order of individually, in groups, or pairings. A resin transfer molding (RTM) system for performing the process includes a mold having a cavity. A set of injection ports feed one or more continuous channels between the cavity and a reservoir of resin. A numerical controller selectively activates the injection ports to overflow the resin into the cavity in any order of individually, in groups, or pairing. |
US11407186B2 |
Fiber application head with flexible roller provided with an anti-adherent sheath
A fiber application head for producing composite material parts, comprising a compacting system comprising a compacting roller comprising a rigid central tube and at least one cylindrical part made of a flexible material and assembled on said central tube, and an anti-adherent sheath covering the cylindrical part, and a heating system that is able to emit thermal radiation in the direction of the (s). The anti-adherent sheath has lateral portions extending beyond the cylindrical surface of the cylindrical part in the direction of the rotation axis of the roller, the assembly of the anti-adherent sheath to said cylindrical part being carried out by the lateral portions. |
US11407182B1 |
Depth control of seal line penetration for rotary ultrasonic horn/anvil welding without mechanical stop
An apparatus for joining a first film portion and a second film portion together along a seal line. The apparatus includes a horn and an anvil. The anvil is positionable in close proximity to the horn. Either the horn or the anvil has a face with a width dimension and a circumference and is rotatable about a rotation axis. The face has a raised profile, and a height of the raised profile has a dimension corresponding to 50% to 150% of a thickness of the first film portion or the second film portion. The face is positioned such that the raised profile extends along the circumference such that continuous running contact is provided between the raised profile and the other of the one of the horn or the anvil when rotated about the rotation axis, to form the seal line without any external structure to control a distance between the horn and the anvil. |
US11407179B2 |
Recoater automated monitoring systems and methods for additive manufacturing machines
A system monitoring an additive manufacturing (AM) machine recoat operation includes an automatic defect recognition subsystem having a predictive model catalog each applicable to a product and to one recoat error indication having a domain dependent feature, the predicative models representative of a recoat error indication appearance at a pixel level of an image captured during recoat operations. The system includes an online monitoring subsystem having an image classifier unit that classifies recoat error indications at the pixel level based on predictive models selected on their metadata, a virtual depiction unit that creates a virtual depiction of an ongoing AM build from successive captured image, and a processor unit to monitor the build for recoat error indications, classify a detected indication, and provide a determination regarding the severity of the detected indication on the ongoing build. A method and a non-transitory computer-readable medium are also disclosed. |
US11407178B2 |
Pressure sensing in an additive manufacturing system
An additive manufacturing system includes an extruder that includes a drive mechanism, a nozzle, and a pressure sensor. The drive mechanism is configured to feed a molten consumable material. The nozzle is attached at a distal end of the extruder and includes a nozzle tip, through which the molten consumable material is discharged as an extrudate. A pressure interface is fluidically coupled to an interior cavity of the nozzle. The pressure sensor is configured to operably measure a pressure within the interior cavity of the nozzle through the pressure interface. |
US11407172B2 |
Recoater using alternating current to planarize top surface of powder bed
A system for recoating a powder bed includes a platform holding a powder bed, a brush and an electrode assembly including an electrode and insulating shield. After powder is distributed on the powder bed the top surface of the powder bed is smoothed by the brush. A voltage supply produces a high voltage alternating current and communicates with the powder bed and the electrode. When the electrode assembly is positioned over the powder bed, the shield is between the electrode and powder bed top surface. The voltage supply produces a high voltage alternating current that creates an alternating electric field between the electrode and the powder bed that causes the powder on the top surface to oscillate in a region between the shield and the bed and then reposition themselves on the bed such that the top layer of the powder bed is smoother than it was prior to when the powder particles began oscillating. |
US11407171B2 |
Liquid cooling for pellet extruder in a fused deposition modeling system
In the context of a system that uses a pellet-type extruder head to form solid objects by moving the extruder relative to a build surface while melting and extruding pellets of raw material, systems and methods are provided which comprise cooling at least a portion of a pathway by which the pellets of raw material are conveyed to a rotating extruder lead screw of the extruder head. |
US11407167B2 |
Three-dimensional object manufacturing method and three-dimensional object manufacturing system
In a three-dimensional object manufacturing method using a three-dimensional object manufacturing device for manufacturing a three-dimensional object by layering and stacking an ink layer in which a surface is flattened by a flattening roller for removing one part of the surface of the ink layer to adjust a thickness of the ink layer to a thickness t, where when forming ink layers with an inkjet head, an ink ejection amount reduction region in which an ejection amount of ink ejected by the inkjet head is reduced from an amount corresponding to the thickness t in a part corresponding to an interior of the three-dimensional object, and when forming the ink layers on an upper side of the specific ink layers with the inkjet head, an ejection amount of ink ejected by the inkjet head is increased from an amount corresponding to the thickness t. |
US11407156B1 |
Molding system for preparing an injection-molded article
The present disclosure provides an injection-molding system for preparing an injection-molded article using a computer-aided engineering (CAE) simulation. The molding system includes a molding machine; a mold disposed on the molding machine and having a mold cavity for being filled with a molding resin; a processing module configured to generate a stress distribution of the molding resin in the mold cavity based on a molding condition for the molding machine, wherein the stress distribution of the molding resin is generated by taking into consideration an elastic effect of the molding resin; and a controller coupled to the processing module and configured to control the molding machine with the molding condition using the generated stress distribution of the molding resin to perform an actual molding process for preparing the injection-molded article. |
US11407154B2 |
Method for producing a vehicle trim part
A method for producing a trim part (1) with a visible side (S) for use in vehicles has steps of producing a support substrate (2) from a fiber composite material. The fiber composite material is injected into a mold cavity of an injection mold. A surface is formed on a first side of the support substrate (2) that faces the visible side (S) of the trim part (1). A lacquer layer (3) is formed by directly coating the surface of the support substrate (2). The lacquer layer (3) is coated with a protective layer (4). |
US11407153B2 |
Method for producing a cladding part for vehicles
A method for producing a cladding part for vehicles with a cladding part body that forms a cladding in the mounted state. A sandwich panel is formed and extends two-dimensionally in a plane with at least one transparent thermoplastic upper layer, a prefabricated, postprocessing-free intermediate layer, and a thermoplastic base layer. The at least three-layered sandwich plate is subsequently three-dimensionally formed under the influence of heat into a sandwich element forming the cladding part body. |
US11407142B2 |
Table saw
A table saw includes a table, a saw unit movably coupled underneath the table, a riving knife extending through the table, and a quick-release assembly selectively coupling the riving knife to the table. The quick-release assembly includes a mounting plate coupled to the table and a clamping plate movable relative to the mounting plate between a clamping position, in which the riving knife is clamped between the mounting plate and the clamping plate to secure the riving knife to the table, and a release position, in which the riving knife is releasable from the table. The quick-release assembly further includes a pin coupled for movement with the clamping plate and a handle pivotably coupled to the pin. The pin has a cam portion engageable with the saw unit. The clamping plate is movable between the clamping position and the release position in response to pivoting movement of the handle. |
US11407139B2 |
Lumber handling and cutting apparatus
Various embodiments of the present disclosure provide a lumber handling and cutting apparatus, including an incoming material conveyor assembly, a material infeed assembly adjacent to the incoming material conveyor assembly, a cutting assembly adjacent to the material infeed assembly, a material outfeed assembly adjacent to the cutting assembly, an outgoing material conveyor assembly adjacent to the cutting assembly, and a printer assembly adjacent to the incoming material conveyor assembly and the material infeed assembly. |
US11407138B2 |
Electric tool
An electric tool includes a functional piece, a motor, a case and a fan. The case includes a motor case portion. An airflow inlet and an airflow outlet are formed in the case. When the fan operates, an airflow at the airflow inlet is taken out and is directed to the airflow outlet after the airflow flows through the motor. The motor case portion includes an encircling portion which encircles the motor and an end portion arranged on one end of the encircling portion. A stopping piece stops the airflow from flowing back from one side of the motor to the other side. |
US11407137B2 |
Conveyor system for conveying food products and associated operating method
The invention concerns a conveyor system (2) for formatting slice-shaped food products in product stacks. The conveyor system (2) comprises an inlet (4), a lower product conveyor (8), an upper product conveyor (7, 9), a vertically swivelling distributor conveyor (6) for distributing the incoming food products selectively to the lower product conveyor (8) or to the upper product conveyor (7, 9), an output conveyor (10) receiving the food products partially stacked from the lower prod-uct conveyor (8) and the upper product conveyor (7, 9), and an outlet (11) for outputting the stacked food products in product rows. The invention provides that the individual conveying tracks (6G, 6H) of the distributor conveyor (6) can be swivelled vertically independently of one another in order to forward the incoming food products individually for each conveying track selectively to the lower product conveyor (8) or to the upper product conveyor (7, 9). The invention also includes a corresponding operating method. |
US11407135B2 |
Longitudinal cutting of a band of a soft food mass
A device for the longitudinal cutting of a wide food band of a soft food mass which is moved in a conveyance direction on a conveyor belt, wherein a cutting cylinder rotating in the conveyance direction is provided on which is mounted a number of cutting disks disposed coaxially to the rotational axis A for cutting into the food band with the edge thereof, wherein a comb having a plurality of comb tines is provided, which in an operating position engage into the intermediate spaces between the cutting disks during the longitudinal cutting in order to hold down the cut strips on the conveyor belt, wherein the comb is held on a comb holder so as to be pivotable about the rotational axis, wherein the comb holder can be transferred from the operating position and a maintenance position by pivoting about the rotational axis. |
US11407134B2 |
Finished products formed from cutting convolutely wound logs of web materials
Described herein is an array of finished products, each finished product in said array may have a Percent Compressibility of greater than 3.00% and an actual length ranging from about 10.955 inches to about 11.045 inches. The finished products may be paper towels, where the actual length is different for at least two finished products of the array and where at least one of the finished products of the array of finished products may comprise a protruding core and where at least one of the finished products may comprise a hidden core, and where each of the finished products are in a package. |
US11407130B2 |
Knife assembly having a spacer or switch button including tritium
A knife assembly includes a handle having a first and second handle portion each extending in spaced relationship with one another between a first and second knife end to define a working gap. A knife blade is pivotably secured to the second knife end and pivotable between a closed and engaged position. A switch button is interconnected to the handle for releasing the knife blade from the closed or engaged positions. A spacer is disposed within the working gap and extends between the first and second handle portions. A vial of tritium is housed within the switch button for allowing tritium produced by the tritium vial to be viewable by a user of the knife assembly. |
US11407129B2 |
Cutlery implement with continuous longitudinal ridge
A cutlery implement or cutting instrument having a blade with opposed side surfaces, a knife edge extending along one terminal edge of the blade, and a narrow continuous longitudinally extending ridge of either hemispherical cross-sectional shape or rectangular cross-sectional shape extending along a pre-determined length of the knife edge at a pre-determined continuous spaced distance from the knife edge. The rectangular cross-sectional shape includes fillets on each opposite side thereof for providing a smooth transition to the blade surface. The narrow longitudinally extending ridge protrudes from at least one or both of the opposed side surfaces of the blade. |
US11407126B1 |
Knife with handle inlay
A foldable knife having a handle inlay through which the knife blade can be viewed may include a knife handle having an interior handle liner and at least one outer handle portion on the handle liner. At least one knife handle inlay may be provided in the knife handle. The knife handle inlay may include a walled or ridged inlay structure which extends from the handle liner and has a selected size and shape. An inlay window may extend through the outer handle portion. The inlay window may generally correspond to a size and shape of the inlay structure and the inlay structure extends through the inlay window. |
US11407125B2 |
Sensorized robotic gripping device
A robotic gripping device is provided. The robotic gripping device includes a palm and a plurality of digits coupled to the palm. The robotic gripping device also includes a time-of-flight sensor arranged on the palm such that the time-of-flight sensor is configured to generate time-of-flight distance data in a direction between the plurality of digits. The robotic gripping device additionally includes an infrared camera, including an infrared illumination source, where the infrared camera is arranged on the palm such that the infrared camera is configured to generate grayscale image data in the direction between the plurality of digits. |
US11407123B2 |
Systems and methods for a telescoping suction gripper assembly
Systems and methods for a telescoping suction gripper assembly are provided. In one embodiment, a robotic system comprises: a robot comprising a robotic actuator and at least one robotic arm mechanically coupled to the robotic actuator; a telescoping suction gripper assembly comprising a telescoping member and a suction gripper mechanism, wherein a first end of the telescoping member is coupled to a vacuum supply conduit via a first flexible conduit member and a second end of the telescoping member is coupled to the suction gripper mechanism by a second flexible conduit member, and wherein the suction gripper mechanism is pivotally coupled to the at least one robotic; wherein the telescoping member is configured to adjust in length in response to the at least one robotic arm relocating the suction gripper mechanism from a first position to a second position. |
US11407122B2 |
Dovetail tool changer for industrial manipulators
A dovetail tool changer includes a first plate to be constrained to an external handling system, a second plate to be constrained to a tool and locking device to lock the second plate in the first plate. The second plate is insertable along a longitudinal direction in a pocket defined in the first plate, both plates have complementary cross sectional shapes and define a dovetailed coupling. The locking device includes at least one floating element movable between a lock position at which it exerts a thrust onto the second plate preventing disengagement thereof from the first plate, and an unlock position, at which the second plate can be separated from the first plate. The locking device includes at least one thrust element connected to the at least one floating element, which are together able to be displaced along a first direction in response to an exerted user force. |
US11407120B2 |
Control device, and control method
To provide a control device and a control method enabled to more simply execute initialization of a force sensor included in a legged walking robot. Provided is a control device including: a leg control unit that controls at least one or more legs of a legged walking robot including a plurality of legs, and stores a force sensor provided in each of the legs in a predetermined space in which the force sensor provided in each of the legs is in a non-contact state; and an initialization execution unit that performs initialization of the force sensor provided in each of the legs. |
US11407110B2 |
Real time feedback and dynamic adjustment for welding robots
Systems and methods for real time feedback and for updating welding instructions for a welding robot in real time is described herein. The data of a workspace that includes a part to be welded can be received via at least one sensor. This data can be transformed into a point cloud data representing a three-dimensional surface of the part. A desired state indicative of a desired position of at least a portion of the welding robot with respect to the part can be identified. An estimated state indicative of an estimated position of at least the portion of the welding robot with respect to the part can be compared to the desired state. The welding instructions can be updated based on the comparison. |
US11407104B2 |
Tooth contact position adjustment amount estimation device, machine learning device, and robot system
A tooth contact position adjustment amount estimation device that performs processing with respect to estimating a tooth contact position adjustment amount for dimensional data of parts constituting a power transmission mechanism according to the present invention, comprising: a machine learning device that performs processing with respect to estimating the tooth contact position adjustment amount for the dimensional data of parts constituting the power transmission mechanism, wherein the machine learning device observes part dimensional data, which is the dimensional data of parts constituting the power transmission mechanism, as a state variable indicating a current state of an environment, and performs processing with respect to estimating the tooth contact position adjustment amount for the dimensional data of parts constituting the power transmission mechanism in assembling the power transmission mechanism by performing processing with respect to machine learning based on the observed state variable. |
US11407103B2 |
Intelligent gripper with individual cup control
Systems and methods related to intelligent grippers with individual cup control are disclosed. One aspect of the disclosure provides a method of determining grip quality between a robotic gripper and an object. The method comprises applying a vacuum to two or more cup assemblies of the robotic gripper in contact with the object, moving the object with the robotic gripper after applying the vacuum to the two or more cup assemblies, and determining, using at least one pressure sensor associated with each of the two or more cup assemblies, a grip quality between the robotic gripper and the object. |
US11407102B2 |
Grasping robot and control program for grasping robot
A grasping robot includes: a grasping mechanism configured to grasp a target object; an image-pickup unit configured to shoot a surrounding environment; an extraction unit configured to extract a graspable part that can be grasped by the grasping mechanism in the surrounding environment by using a learned model that uses an image acquired by the image-pickup unit as an input image; a position detection unit configured to detect a position of the graspable part; a recognition unit configured to recognize a state of the graspable part by referring to a lookup table that associates the position of the graspable part with a movable state thereof; and a grasping control unit configured to control the grasping mechanism so as to displace the graspable part in accordance with the state of the graspable part recognized by the recognition unit. |
US11407098B2 |
Smart push button device utilizing MEMS sensors
A device for generating a control signal based on the linear movement of a linear member is provided. The device includes a linear member, a rotatable member, a first inertial measurement unit (IMU) coupled to the rotatable member and a second IMU having a fixed position. The device also includes a processing circuit which uses sensing signals from the IMUS to determine an attitude of the first IMU referenced to the second IMU and generate a control signal based on the attitude. |
US11407097B2 |
Power base module
A drive base module of a modularly constructed multifunctional handheld machine is configured to connect to at least one attachment device. The drive base module includes at least one connection device including at least one drive-technological interface and/or a data-technological interface configured to connect to the at least one attachment device. The drive base module further includes at least one drive unit configured to drive the at least one attachment device in a state in which the at least one attachment device is connected to the at least one connection device. The drive base module further includes at least one rechargeable battery unit; and at least one information output unit configured to output information to an operator acoustically and/or haptically. |
US11407096B2 |
Multi-purpose tool and attachments
A handheld multi-tool is provided. The tool has an elongate central handle with an integrally formed tool at each opposite end of the handle. A plurality of additional tools may be attached to the multi-tool by slideably fitting over one of the integrally formed tools, leading to a wide variety of operational modes for the multi-tool. |
US11407095B2 |
Striking tool
A striking tool includes: a driver which is provided to be slidable toward an ejecting port provided in a tip end of the striking tool so as to strike out a fastener from the ejecting port; a plunger to which the driver is coupled; a plunger urging member which is configured to urge the plunger toward the ejecting port: and a drive mechanism which is configured to move the plunger to accumulate urging force in the plunger urging member. A standby position of the plunger before striking out the fastener can be switched between a usual standby position and a standby position for maintenance closer to the ejecting port than the usual standby position. |
US11407092B2 |
Electric pulse tool
An electric pulse tool performs a tightening operation in which torque is delivered in pulses to tighten a screw joint. The electric pulse tool includes an output shaft, a torque sensor to determine a torque value associated with tightening of the screw joint, and an angle sensor to determine an angular displacement of the screw joint. The tool provides low torque pulses of a torque value of less than 15 percent of an electric pulse tool max torque value on the output shaft until a low threshold torque value is reached. Next the tool starts measuring an angular displacement of an element of the screw joint and provides tightening torque pulses of a torque value of more than 15 percent of the electric pulse tool max torque value on the output shaft. The tool stops providing torque pulses on the output shaft when a target parameter is reached. |
US11407091B2 |
Power tool
A power tool includes a motor disposed in a motor housing, a handle extending downward from the motor housing, a main switch provided on the handle and configured to switch the motor ON and OFF, and a state-changing operation part located on a lower portion of the motor housing or on an upper-end portion of the handle. The state-changing operation part is located upward of the main switch and is configured to effect a change of a rotational state of the motor, other than a direction of rotation of the motor, or an illumination level of a light. |
US11407090B2 |
Tool bit
A tool bit includes a hexagonal drive portion, a working end, and a shank interconnecting the drive portion and the working end. The shank includes an outer peripheral surface. The outer peripheral surface tapers an entire length of at least one of the shank and the working end in a direction away from the drive portion. |
US11407087B2 |
Abrasive product
Provided is a flexible abrasive product (1) comprising a knitted cloth (2) on a first side of the flexible abrasive product (1), grinding agents (50) applied on a second side of the flexible abrasive product (1) facing the first side, and a plurality of loops (71) protruding from the cloth (2) and from the first side, each loop (71) being formed by a pair of bottom-half arcs (76) connected by a protruding head (77) and the loops (71) being arranged in rows extending in the wale direction (W) of the cloth (2), wherein the bottom-half arcs (76) are interlaced in the cloth (2), and the protruding heads (77) of the loops (71) are interconnected with one another outside of the cloth (2) so as to form rows (73) of interconnected loops (71), which rows (73) extend in the wale direction (W) of the cloth (2). |
US11407086B2 |
Method of manufacturing an abrasive member, in particular rotary abrasive disc, and abrasive member, in particular rotary abrasive disc
A method of manufacturing an abrasive member, in particular having the general shape of a disc such as a cutting or grinding disc, comprises arranging a reinforcing insert or reinforcing member into a mold between a layer of curable abrasive resin compound, in particular a layer of curable abrasive granulate, a backing member such that at least a section of the reinforcing insert or reinforcing member is in direct physical contact with the curable abrasive resin compound, the reinforcing insert or reinforcing member is at least partially covered by the backing member and at least a section of the backing member is in direct physical contact with the curable abrasive resin compound; bonding the reinforcing insert or reinforcing member and the backing member by curing the curable abrasive resin compound, wherein the cured abrasive resin compound forms an abrasive layer of the abrasive member. |
US11407077B2 |
Device for repairing appearance defects and repair method
The present disclosure provides a device for repairing appearance defects and repair method. The device comprises: a moving platform and at least one repair mechanism, each the repair mechanism comprises at least one sub-repair mechanism, each the sub-repair mechanism comprises a first moving portion, a second moving portion, and a repair portion; the moving platform is configured to support an apparatus to be repaired and move in a first direction to drive the apparatus to be repaired to move in the first direction; the first moving portion is configured to move in a second direction to drive the repair portion to move in the second direction, and the second direction intersects the first direction perpendicularly; the second moving portion is configured to move in a third direction to drive the repair portion to move in the third direction. |
US11407074B2 |
Processing machine line
A processing machine line including multiple processing modules arranged in a width direction and loaded on a base where a machine body is movable in a front-rear direction; an automatic workpiece transfer machine to perform transferring of a workpiece by moving a conveyance robot in front of the base; an external cover to cover the processing module; a front cover to form a conveyance space of the conveyance robot, the front cover being provided with, for each processing module, an upper section cover that is open-and-closable in a lifting up manner, and a lower section cover configuring a cover front surface with the upper section cover; and a chip receiving box to be removable and attachable by being attached between the lower section cover and the base via an installation bracket that is attachable and removable with respect to a top section of the lower section cover. |
US11407071B2 |
Machine tool
A machine tool has: a main shaft head that supports the main shaft; a main shaft head support part which supports the main shaft head such that the main shaft head can rotate around a first axis that extends perpendicular to the main shaft axis of rotation; a first rotary feed shaft device which is provided in the main shaft head support part, and rotates and feeds the main shaft head around the first axis; a saddle which supports the main shaft head support part such that the main shaft head support part can rotate around a second axis that is perpendicular to the first axis and inclined with respect to the vertical direction; and a second rotary feed shaft device which is provided in the saddle, and rotates and feeds the main shaft head support part around a second axis of rotation. |
US11407067B2 |
Method for repairing a part
Methods for repairing a coated part with holes extending therethrough are disclosed. In one embodiment, a method comprises receiving a part where a coating on a first side of the part at least partially obstructs a first opening of a hole on the first side of the part. Measured hole data indicative of a position of a second opening of the hole on a second side of the part opposite the first side is then acquired. Based on the measured hole data, the first opening of the hole is cleared of the coating by laser drilling via the second opening of the hole. |
US11407065B2 |
Systems and methods for manufacturing film cooling hole diffuser portion
A gas path component for a gas turbine engine includes a film cooling hole disposed in the gas path component. The film cooling hole includes a metering section, a diffuser, and a tapered surface extending between the metering section and the diffuser. The tapered surface is oriented between twenty degrees and seventy degrees with respect to a centerline axis of the metering section. The tapered surface is oriented at an obtuse angle with respect to an immediately adjacent surface of the diffuser, the obtuse angle is open towards the centerline axis. The tapered surface is configured to mitigate flow separation in the diffuser. |
US11407059B2 |
Friction stir welding (FSW) tool with adjustable probe length and shoulder groove depth
Disclosed is a friction stir welding tool with an adjustable probe length and shoulder groove depth, wherein a support shaft, made of a material having low thermal conductivity so as to inhibit thermal conduction between a probe and a shank, is coupled to the center of an upper locking member together with the shank, the probe and inner and outer shoulders are coupled inside a lower part of the upper locking member, and a lower locking member is fastened and fixed to the lower part of the upper locking member, and a washer and a locking nut are fastened to an upper part of the lower locking member, whereby the locking nut pushes the lower locking member via the washer. |
US11407058B2 |
Cladded amorphous metal products
An embodiment relates to a cladded composite comprising a cladding layer of a bulk metallic glass and a substrate; wherein the bulk metallic glass comprises approximately 0% crystallinity, approximately 0% porosity, less than 50 MPa thermal stress, approximately 0% distortion, approximately 0 inch heat affected zone, approximately 0% dilution, and a strength of about 2,000-3,500 MPa. |
US11407057B2 |
Bonding system for dual walled turbine components
A bonding system is used for bonding a cover sheet to a core to form or repair a dual wall structure. The bonding system includes a plurality of bonding probes and controller circuitry. The bonding probes include a three dimensional (3D) contoured tip configured to align with a predetermined area of a 3D contoured cover sheet of a dual wall structure. The controller circuitry comprises processor circuitry and sensor circuitry. The sensor circuitry provides a location of an area of the 3D contoured cover sheet for bonding. The processor circuitry identifies a bonding probe having a contacting area that aligns with the 3D contour of the cover sheet in the location provided by the sensor circuitry. |
US11407056B2 |
Pierce metal for joining different materials and method of joining different materials using pierce metal
A pierce metal includes a head and a shaft. The shaft is configured to penetrate through an aluminum die-cast member with a protruded tip surface of the shaft being exposed from the aluminum die-cast member, and an outer peripheral surface of the shaft is configured to come into contact with a through-hole of the aluminum die-cast member, upon joining the aluminum die-cast member and the iron-based member together. The head and the iron-based member in contact with the protruded tip surface are configured to be held under pressure and applied with electric power by weld electrodes to perform spot welding of the protruded tip surface and the iron-based member, upon joining the aluminum die-cast member and the iron-based member together. The outer peripheral surface includes a non-contact part configured to come into non-contact with the through-hole in a state in which the shaft is penetrated through the aluminum die-cast member. |
US11407053B2 |
Welding device having two welding torches and control unit for starting the arc ignition process, and welding method for welding with two welding processes under an adapted starting process
A welding device has a central unit and a welding torch unit, which can be connected to the central unit. The central unit includes at least one welding current source for providing electric current needed to operate the welding torch unit and includes a control unit. The welding torch unit includes at least a first welding torch with a first welding wire and a second welding torch with a second welding wire. The control unit is configured to carry out a starting process in such a way that firstly a first arc ignition takes place at one of the two welding torches and after a waiting time since the first arc ignition has passed, a second arc ignition takes place at the other of the two welding torches, which until then was not ignited. |
US11407050B2 |
Electrical discharge machining device, electrical discharge machining method, and design method
An electrical discharge machining device provided, using a floating capacitance to provide a machining target with improved surface roughness. An electrical discharge machining device 1 includes a current supply circuit 3 that supplies a current to a gap between an electrode 17 and a machining target 19 so as to provide electrical discharge machining. A floating capacitance portion 21 occurs between the electrode 17 and the machining target 19 in the electrical discharge machining. The floating capacitance portion 21 supplies its stored charge to the gap in the electrical discharge machining. A capacitor 11 stores a charge before the floating capacitance portion 21 is discharged. After the floating capacitance portion is discharged, the capacitor 11 charges the floating capacitance portion 21. The floating capacitance portion 21 is discharged again after it is charged. Such an operation generates a pulse current, thereby providing electrical discharge machining. |
US11407047B2 |
Reamer
A reamer includes a core, a plurality of outer-circumference cutting edges provided on an outer circumference of the core and made of a hard tool material, and a margin provided on a rear side of each the plurality of outer-circumference cutting edges in a rotational direction. A distance from an axis of rotation to a position of a center of gravity of the reamer is greater than 0.01 mm and not greater than 0.5 mm. |
US11407043B2 |
Cutting insert
Provided is a cutting insert, within which a burr being generated at an outer edge of a finished surface is inhibited and chipping of the cutting insert is inhibited even when the cutting insert is formed to have multiple corners superior in economical efficiency. The cutting insert has an upper surface, a lower surface on an opposite side to the upper surface, and a circumferential side surface connecting the upper surface and the lower surface to each other. A first ridgeline at which the upper surface and the circumferential side surface intersect each other includes major cutting edges and wiper cutting edges which are alternately disposed one by one, and corners each disposed between each of the major cutting edges and each of the wiper cutting edges. A distance between the corners that are adjacent to each other is equal to or less than 60% of a diameter of an inscribed circle of the first ridgeline. The corner that is positioned at one end of the wiper cutting edge is formed at a deburring cutting edge that intersects the wiper cutting edge at an angle smaller than an angle formed by the major cutting edge and the wiper cutting edge. The corner that is positioned at the other end of the wiper cutting edge is formed at a corner cutting edge having a curvature larger than that of the wiper cutting edge. |
US11407039B2 |
Drill bit
A drill bit includes a body having a first end, a second end opposite the first end, and an axis of rotation extending centrally through the body. The drill bit includes a cutting head with a cutting tip on the axis of rotation and a cutting portion. The cutting portion includes first tip surfaces on opposite sides of the axis of rotation and second tip surfaces on opposite sides of the axis of rotation. Each first tip surface extends radially outward from the cutting tip to a corresponding second tip surface. Each second tip surface extends from a corresponding first tip surface to an outer periphery of the body. The first tip surfaces define a first tip angle measured through the axis of rotation that is oblique. The second tip surfaces define a second tip angle measured through the axis of rotation that is smaller than the first tip angle. |
US11407030B2 |
Silver powder and method for producing same
There is provided a silver powder which has a small average particle diameter and a small thermal shrinkage percentage, and a method for producing the same. While a molten metal of silver heated to a temperature (1292 to 1692° C.), which is higher than the melting point (962° C.) of silver by 330 to 730° C., is allowed to drop, a high-pressure water is sprayed onto the molten metal of silver (preferably at a water pressure of 90 to 160 MPa) to rapidly cool and solidify the molten metal of silver to powderize silver to produce a silver powder which has an average particle diameter of 1 to 6 μm and a shrinkage percentage of not greater than 8% (preferably not greater than 7%) at 500° C., the product of the average particle diameter by the shrinkage percentage at 500° C. being 1 to 11 μm·% (preferably 1.5 to 10.5 μm·%). |
US11407023B2 |
Cold rolling machine and method for producing a profile on a workpiece
A cold rolling machine and method for producing a profile on a workpiece. The cold rolling machine having two constructed tool units. Each tool unit has at least one rolling rod extending in the longitudinal direction, a tool slide, a slide drive device, a pivoting carrier and a pivot drive. The at least one rolling rod is fastened to the tool slide and can be moved in the longitudinal direction by the slide drive device. The pivoting carrier can be pivoted about a pivot axis extending in the longitudinal direction by a pivot drive. The tool slide is arranged on the pivoting carrier. An angle of inclination can thereby be set between the two rolling rods, which angle of inclination can have, for example, a value of 0 degrees to 2.0 degrees or to 0.2 degrees. Conical profiles can thereby be produced in the workpiece. |
US11407021B2 |
Forming finished parts using a movable gantry press and a plurality of die assemblies
Systems, devices, and methods for fabricating finished parts include a system that includes a plurality of die assemblies located at a plurality of respective locations, each die assembly being configured to fabricate a respective finished part. The system further includes a movable gantry press and a robot, each configured to move between the plurality of respective locations. The system further includes a controller configured to receive a input to fabricate a finished part and identify a die assembly of the plurality of die assemblies. The controller is further configured to instruct the movable gantry press and the robot to move to the location of the die assembly. The controller is further configured to instruct the robot to load a blank into the die assembly, and instruct the movable gantry press to operate the die assembly to fabricate the finished part. |
US11407017B2 |
Machine and method for bending oblong elements, preferably metal, such as bars, rod, section bars or suchlike
A machine for bending oblong elements, preferably metal, includes a feed unit configured to feed at least one of the oblong elements along a longitudinal axis. A bending device is located downstream of the feed unit and a curving unit is disposed downstream of the bending device and is configured to curve the oblong element along part of its oblong development. |
US11407015B1 |
Method of using pipeline flow for pipeline cleaning
The method of using the flow within a pipeline to clean the inner wall of the pipeline including placing the cleaning pig into the pipeline to be cleaned at a first location, using a restraining rope or cable to cause the cleaning pig to move along the pipeline at a speed slower than the speed of the flow within the pipeline and thereby causing a pressure differential between the upstream side and the downstream side of the cleaning pig, providing one or more jetting nozzles and using the pressure differential to jet a portion of the flow within the pipeline through the one or more jetting nozzles onto the inner wall of the pipeline while providing a flow area through the cleaning pig to bypass the portion of the flow which does not pass through the one or more jetting nozzles. |
US11407013B2 |
Apparatus and method for cleaning lidar sensor
An apparatus for cleaning a lidar sensor may include: a contaminant detector configured to detect a contaminant adhering to a window cover of the lidar sensor; a rotator configured to rotate the window cover; a cleaner configured to clean the window cover; and a controller configured to control the rotator to rotate the window cover to a cleaning region for removing the contaminant, and control the cleaner to remove the contaminant, when the contaminant is detected by the contaminant detector. |
US11407012B2 |
Sonic cleaning of optical fiber draw furnace
A process for cleaning particulate matter from the interior of a muffle of an optical fiber draw furnace includes propagating sound waves through the interior of the muffle at a frequency of from about 75 Hz to about 5000 Hz and an intensity of from about 110 dB to about 160 dB. |
US11407008B2 |
Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly
The present invention relates to an ultrasound transducer assembly (10), in particular for intra vascular ultrasound systems. The assembly (10) comprises a transducer array (12) including a plurality of transducer elements (14) for transmitting and receiving ultrasound waves. Two support elements (16, 18) are provided for supporting the transducer array (12) in a curved or polygonal shape. The support elements (16, 18) are connected via a flexible connection layer (20) to the transducer array (12) for flexibly connecting the support elements (16, 18) to the transducer array (12). |
US11407001B2 |
Curtain applicator and method for applying an application medium
A curtain applicator for applying a liquid or pasty application medium to at least one surface of a running material web, in particular a fibrous web. The curtain applicator has an applicator nozzle, in particular a slotted nozzle, which under the effect of gravity, and optionally with further forces, is suitable for dispensing a single-tier or multi-tier curtain onto the surface of the material web. The curtain applicator further has a wiping device which is suitable for keeping entrained air carried by the material web away from the curtain. Moreover, there is provided at least one further blocking device which is suitable for keeping air movements of the ambient air away from the curtain. |
US11406997B2 |
Apparatus for generating and optically characterizing an aerosol
An apparatus having: a vessel for containing a suspension of a liquid and solid particles; a tube having a narrowed portion to draw the suspension from the vessel into the tube when a gas flows through the tube; an aerosol generator coupled to the tube for forming an aerosol from the suspension; a dehydrator coupled to the aerosol generator for removing the liquid from the aerosol forming a dried aerosol; a multiple-pass spectroscopic absorption cell coupled to the dehydrator to pass the dried aerosol into the absorption cell; and a Fourier transform spectrometer coupled to the absorption cell to measure an absorption spectrum of the dried aerosol. |
US11406995B2 |
Material spray gun
A spray gun includes a gun body and valves configured to control flow of material and air through the gun body. A trigger is mounted to the gun body and is disposed relative to the valves such that the trigger actuates the valves in sequence to begin air flow and material flow. A sensor senses when the trigger is in an actuated state and the sensor causes a pump to begin pumping material to the spray gun. Release of the trigger causes the trigger to leave the actuated state. A detent mechanism holes the trigger in a detent state intermediate the actuated state and a resting state. The sensor does not sense the trigger with the trigger in the detent state. The trigger maintains the valves open with the trigger in the detent state. |
US11406994B2 |
Variable flow rate hand showers and showerheads
A shower device includes an elongated hollow waterway, a spray head configured to emit water, and a valve. The elongated hollow waterway extends in a longitudinal direction and has a first end configured to receive water, a second end, and an internal fluid passage extending from the first end to the second end. The second end has a port extending in a radial direction from the internal fluid passage through the waterway. The valve is configured to control a water flow rate from the internal fluid passage of the waterway to the spray head. The valve includes a valve body that surrounds the port and a control member operatively coupled to the valve body and surrounding at least a portion of the valve body. Rotation of the control member and valve body relative to the waterway provides a variable adjustment of the water flow rate to the spray head. |
US11406979B2 |
Rotatable cartridge for processing and analyzing a biological sample and dispensing method therewith
An automatic analyzer cartridge, spinnable about a rotational axis, has fluid and aliquoting chambers, a metering chamber connected to a vent that is nearer to the rotational axis than the metering chamber, first and second ducts connecting the fluid and aliquoting chambers, and the metering and aliquoting chambers, respectively. Metering chamber side walls taper away from a central region, wherein capillary action next to the walls is greater than in the central region. Fluid flows to the metering chamber using capillary action via the second duct that has an entrance and exit in the aliquoting and metering chambers, respectively; the exit being closer to the rotational axis than the entrance. A downstream fluidic element connects to the metering chamber via a valve. A fluidic structure receives and processes a biological sample into the processed biological sample and has a measurement structure that enables measurement of the processed biological sample. |
US11406978B2 |
Method for hemostasis testing
A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis. |
US11406975B2 |
Human lymphoid tissue-on-chip
An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels. |
US11406974B2 |
Processing system and method
In accordance with one embodiment, a processing device includes a heated internal wall and a rotating rod positioned within an interior space formed by the heated internal wall. The rotating rod may be hollow and act as an internal heat exchanger. The processing device also includes a plurality of baffles spaced apart from one another along the rotating rod and extending away from the rotating rod towards the heated internal wall. The plurality of baffles or porous, packed basket that rotates with the rotating rod that also may be configured to provide cooling relative to the heated internal wall. The processing device also includes at least one wiper or roller coupled to an edge of at least one of the plurality of baffles or porous, packed basket, coupled to the rotating rod and that contacts the heated internal wall while rotating together with the rotating rod. In another embodiment, a processing device may be used to adsorb reactive gases into a liquid phase while heat is exchanged. |
US11406964B2 |
Heterogeneous catalysts for the synthesis of carbamates
The present invention relates to a catalyst for preparing carbamates, in particular aromatic carbamates, comprising a binary oxide having the formula L1-xMxO2, wherein L is a metal selected from the lanthanoid series and M is a metal selected from the group consisting of Sc, Y, Ti, Zr, Hf, metals from the lanthanoid series and metals from the actinoid series, and wherein x ranges from 0.01 to 0.05. The present invention also relates to a method for producing said catalysts and a method of utilizing said catalysts in the production of carbamates, in particular aromatic carbamates. |
US11406963B2 |
Superabsorbent polymer and preparation method thereof
Provided are a superabsorbent polymer exhibiting more improved absorption rate and liquid permeability as well as excellent basic absorption performance, and a preparation method thereof. The superabsorbent polymer includes a base polymer powder including a crosslinked polymer of water-soluble ethylene-based unsaturated monomers having acidic groups which are at least partially neutralized; and a surface crosslinked layer which is formed on the base polymer powder and in which the base polymer powder is additionally crosslinked via a surface crosslinking agent, wherein the superabsorbent polymer includes 10% by number or more of superabsorbent polymer particles each particle having an aspect ratio of less than 0.5, the aspect ratio defined as the shortest diameter/the longest diameter of the superabsorbent polymer particle, and has SFC in a predetermined range. |
US11406962B2 |
Super absorbent polymer and method for producing same
The present invention relates to a superabsorbent polymer which exhibits more improved liquid permeability while maintaining excellent absorption performance, and suppresses aggregation and caking of particles even under high temperature/high humidity conditions, and to a method for producing the same. The super absorbent polymer comprises: a base polymer powder including a first crosslinked polymer of a water-soluble ethylenically unsaturated monomer having at least partially neutralized acidic groups; and a surface crosslinked layer formed on the base polymer powder and including a second cross-linked polymer in which the first cross-linked polymer is further crosslinked via a surface cross-linking agent, wherein the super absorbent polymer includes aluminum sulfate dispersed in the surface crosslinked layer and alumina dispersed on the surface crosslinked layer. |
US11406952B2 |
Portable custom cosmetic pigment dispenser
A portable custom cosmetic pigment dispenser creates a cosmetic pigment mixture that closely matches a person's skin color. The device is constructed with an RGB sensor at one end that scans the skin and records it in the RGB color space. A processor converts the RGB information into a CYMK+W color space. In an embodiment, a user is presented with a sample of the color as determined by the processor, and has an opportunity to accept or modify the color. Specific quantities of colored pigment are selected based on the corresponding weightings in the CYMK+W space. |
US11406951B2 |
Continuous and forced asphalt mixing production method
Disclosed is a continuous and forced asphalt mixing production method, which relates to the technical field of concrete processing and includes the following steps of: heating a cold aggregate to obtain a hot aggregate, hot mixing and/or cold mixing the milled materials to obtain recycled materials; blending the hot aggregate, the recycled materials, the powder materials and the asphalt to obtain a premix; temporarily storing the premix in a pre-stirring storage bin and then stirring the premix in a forced stirring cylinder, temporarily storing the obtained finished product materials in a finished product storage bin; in the finished product material loading area, unloading into a storage tank of a finished product material conveying vehicle. |
US11406950B2 |
Bubble volume control method and bubble volume controlling apparatus
Provided is a bubble volume control method and apparatus, and more particularly, to a bubble volume control method and apparatus for controlling the volume of a bubble by increasing or decreasing the volume of the bubble by emitting an ultrasonic wave having a resonance frequency corresponding to the size of the bubble located at the bottom of a container containing a liquid, such as water with bubbles composed of air, vapor, etc., toward the bubble by using an ultrasonic generator above the container, and maximizing a function of adjusting the volume of a bubble through a resonance effect by adjusting a liquid surface height of a liquid with the bubble according to a wavelength of an emitted ultrasonic wave. |
US11406949B2 |
Apparatus for agitation of fluids
An apparatus for agitation of fluids is described that comprises an agitation chamber, an impeller configured to have a motor, a shaft, and blades, and a plurality of baffles. Further, the plurality of baffles have a predetermined shape and configuration. Further, the plurality of baffles are placed on a side wall of the agitation chamber. |
US11406948B2 |
Smart entrainment atomisation mixing system
A nozzle for injecting a first liquid mass into a stream of second liquid mass flowing within a pipe, comprising a first, outer, cylinder and second, inner, cylinder concentrically arranged about a nozzle axis, securing means for securing the nozzle to a wall of the pipe with the nozzle axis orthogonal to the pipe wall, the nozzle projecting into an interior of the pipe in use, duct means for receiving the first liquid mass and transporting it to the interior of the inner and outer cylinders, the inner cylinder comprising at least one hole arranged to expel liquid therethrough, and the outer cylinder comprising at least one hole arranged to expel liquid therethrough. |
US11406944B2 |
Carbonation machine and a gas canister for a carbonation machine
A carbonation machine may include a carbonation head, a holder that is configured to hold a gas canister, the holder comprising a connector with a socket configured to enable linear insertion of a valve of the canister into the socket, the socket including a seal with at least one lateral opening to enable fluidic flow between one or more laterally oriented ports of the valve and a conduit of the holder while preventing leakage of gas from the fluidic flow, and a holding mechanism configured to hold a lateral projection from the canister after insertion of the valve into the socket such that the valve remains in the socket, and an activation mechanism configured to operate the valve to release the gas from the canister when inserted into the socket so as to enable the gas to flow via the conduit to the carbonation head. |
US11406940B2 |
Method for reducing monovalent ions in concentrate of nanofiltration system and the nanofiltration system
This specification describes a method for lowering the content of monovalent ions in a final concentrate of a nanofiltration system relative to a brine and a corresponding nanofiltration system. The nanofiltration system comprises at least three stages of nanofiltration, wherein the concentrate from each segment flows into the next segment. A feed stream is sent into one stage to generate a concentrate stream, and a first portion of the concentrate stream is recirculated to the one stage. The pH of the feed stream is controlled in a range of 2-7. The temperature of the feed stream is in a range of 20-60° C. The feed stream includes the recirculated concentrate stream and at least part of a concentrate generated from an upstream stage. The method and the system described herein can reduce the concentration of monovalent ions in the final concentrate during a nanofiltration separation process. |
US11406938B2 |
Process for obtaining carbon dioxide from furnace combustion fumes
A process for obtaining carbon dioxide from furnace combustion fumes is provided. The process comprises removing water vapour occurring in combustion fumes through successive gas compression and expansion steps; separating carbon dioxide from oxygen and nitrogen through the use of a filter comprising a gas-separating material, including fullerenes and zeolites, to obtain substantially pure gaseous carbon dioxide; subsequently optionally producing dry ice through further steps of compression and expansion of the substantially pure gaseous carbon dioxide obtained in the preceding steps. |
US11406936B2 |
H2S gas scrubbing and monitoring system for laboratory applications
A system for scrubbing and monitoring H2S includes: a sample inlet valve that controls an input stream of the hydrocarbon gas from the gas canister; a first scrubber that removes a first portion of H2S from the input stream and that outputs a first stream with less H2S than the input stream; a second scrubber that removes a second portion of H2S from the first stream and that outputs a second stream with less H2S than the first stream; a H2S converter that converts all remaining H2S in the second stream into a di-ketone and that outputs an output stream with a concentration of the di-ketone; an optical detector that measures the concentration of the di-ketone in the output stream; and a processor that determines a concentration of H2S in the second stream based on the concentration of the di-ketone in the output stream. |
US11406934B2 |
Device and system for decomposing and oxidizing gaseous pollutant
The invention provides a device and system for decomposing and oxidizing of gaseous pollutants. A novel reaction portion reduces particle formation in fluids during treatment, thereby improving the defect of particle accumulation in a reaction portion. Also, the system includes the device, wherein a modular design enables the system to have the advantage of easy repair and maintenance. |
US11406931B2 |
Method and apparatus for purification and treatment of air
The invention discloses methods and apparatus(es) for the removal and control of pollutants such as gases and suspended particulates in the air of an enclosed space or an outdoor environment by passing the air through absorbent media. The absorbent media includes any liquid, solid or combination of liquid and solid media that is capable of absorbing a material in which it comes in contact. In one aspect of the invention, formaldehyde is removed by air sparging through a liquid such as water, optionally containing additional scavenging agents. |
US11406925B2 |
Filter support, filter assembly including filter support, and method of modifying filter using filter support
A filter support for a filter is adjustable to modify the size and/or shape of the filter. The filter support may include one or more wedges engaging a wall of the filter, and a connector connecting the one or more wedges to one another. The connector allows selective adjustment of the filter support. |
US11406922B2 |
Security system for fluid filtration device
A security system for a fluid filtration device and, more particularly, a security system that is adapted to pair a filter with a fluid filtration device, log an effectiveness of each individually serialized filter, prevent re-usage of a filter in more than one filtration device and prevent usage of a filter for greater than its preprogrammed lifespan. |
US11406921B2 |
Gasket for screen frame
A screen assembly for a vibrating shaker is provided. The screen assembly utilizes an elastomeric gasket having a flat profile section and a bulb profile section, wherein said bulb profile section has a hollow interior and is configured so as to form a notched profile section where said bulb profile section connects to said flat profile section. |
US11406918B2 |
Adjustable particle separator system and method of using same
An adjustable separation system for separating particles suspended in a liquid and method of using same are disclosed. Embodiments are directed to an adjustable separation system that includes an adjustable particle separation channel including: a plurality of plate electrodes; and an adjustable inclination system configured to adjust inclination of the plate electrodes through a range of angles, or an adjustable spacing system configured to adjust spacing between adjacent plate electrodes. The adjustable separation system allows the particle-laden liquid to traverse the plate electrodes within the separation channel, thereby separating the particles from the liquid while using the Boycott effect. These and other embodiments achieve separation of particles suspended in a liquid via an adjustable separation system and, optionally, without the need for manual/technician adjustments, which can result in improved efficiency, quicker separation/operating time, and reduced power consumption and cost. |
US11406917B2 |
Oil droplet flotation unit with weirs and hydraulic means
A flotation apparatus for separating oil from a dispersion containing water as a continuous phase and oil as a dispersed phase. The apparatus comprises a vessel having one or more longitudinal cell sections in its longitudinal direction, at least one of the one or more longitudinal cell sections comprising: an underflow weir, an overflow weir displaced downstream from the underflow weir, a gas injection structure located below the underflow weir or in the channel formed between the underflow weir and the overflow weir, a removal structure for removing a fraction formed during the operation of the flotation apparatus on the liquid level from the liquid level, and a hydraulic structure for hydraulically pushing the fraction formed during the operation of the flotation apparatus on the liquid level into the removal structure using a liquid stream, a liquid/gas stream and/or a gas stream that is ejected by the hydraulic structure. |
US11406913B2 |
Method and apparatus for extracting botanical oils
Various aspects of this patent document relate to a method to extract an oil from a plant material using an apparatus by first exposing the plant material to a heated gas stream at a temperature sufficient to volatilize the oil from the plant material, and then rapidly cooling the gas stream to liquefy the oil. |
US11406911B2 |
Dispersion plate and purification column including the same
Disclosed is a dispersion plate for a purification column including a support plate, at least one first fluid tube penetrating through the support plate, and a plurality of second fluid tubes arranged to be spaced apart from the first fluid tube and surround the first fluid tube, wherein a length of at least one of the second fluid tubes is longer than lengths of another second fluid tubes, and is shorter than or equal to a length of the first fluid tube. |
US11406910B2 |
Apparatus for maximizing effluent liquid evaporation
The present invention generally relates to a system for treating effluent water. More particularly, it provides a robust apparatus for treating waste liquid by optimizing solar and wind energy to maximize the evaporation rate as compare to natural evaporation rate. The main object of the present invention is to provide a system for evaporating RO reject and other effluent liquid and other liquids, by optimizing system to solar and wind energy to maximize vaporization rate and recovery rate at marginal operational cost. |
US11406906B2 |
Network connected controller for direct to cloud gaming
A controller device for user interactivity with a server of a cloud gaming system is provided, including the following: at least one input device that generates inputs for the server; wherein the controller device communicates directly to an access device for connection to a network that connects the controller device to the server without connecting to a client device; wherein the server receives and processes the inputs to render gameplay video that is transmitted over the network for rendering to a display device that is local to the controller device. |
US11406901B2 |
Addressable assets in software development
A method for tracking game asset locations is disclosed. Content is created for an application using a first asset. The first asset includes asset data that describes at least a part of the content associated with the asset. The asset data is placed within one or more files within a location within one or more memories. A catalog associated with the application is created on the server. A catalog entry is created for the first asset. The catalog entry includes an address that uniquely identifies the first asset. A request is received from the application for asset data associated with the first asset, the request including the address. The address and the catalog are used to determine location data associated with the address. The determined location data is used to retrieve the asset data at the determined location. The retrieved asset data is returned to the application. |
US11406898B2 |
Non-transitory computer-readable medium and video game processing system
A non-transitory computer-readable medium including a video game processing program for causing a server to perform functions regarding a search of a moving route in a virtual space is provided. The functions includes: a setting function configured to set a navigation mesh corresponding to a movable area of an object in a virtual space; an arranging function configured to arrange a plurality of waypoints on the set navigation mesh in accordance with a predetermined arrangement rule; a generating function configured to generate a plurality of regions by grouping the plurality of waypoints arranged in the virtual space based on a predetermined classification rule; a determining function configured to determine movable regions based on arrangement of the plurality of regions thus generated; and a searching function configured to search a moving route of the object based on the waypoints included in the determined movable regions. |
US11406897B2 |
Method and system for dynamic control of game audio based on audio analysis
A headset, during play of a particular game, receives a plurality of audio channels carrying game sounds and determines whether a first of the game sounds overwhelms a second of the game sounds. In response to the determination, the headset adjusts a level of one or more of the audio channels such that perceptibility of the second game sound is improved relative to perceptibility of the first game sound prior to the adjustment, wherein for the adjustment, a level of one or more of the audio channels carrying the first game sound is decreased while a level of one or more of the audio channels carrying the second game sound is maintained or increased. The audio channels include three or more audio channels and the adjustment of the level of the audio channels is performed while the three or more audio channels are combined into two stereo channels. |
US11406894B2 |
Online software video capture and replay system
A user-activity video signal can be received. The user-activity video signal can comprise a video capture characterizing a user's interaction with a software application on a client. The software application can have an interface display space on the client and the software application can execute on the client in operation with at least one remote backend computing system. Backend user interaction data corresponding to the user's interaction with the software application as generated by the at least one remote backend computing system can be received. A new video comprising a plurality of divided segments of the user-activity video signal can be generated automatically using the backend user interaction data and a plurality of predefined rules. The new video can be provided. Related apparatus, systems, techniques, and articles are also described. |
US11406890B1 |
Skateboard assembly
A motorized or non-motorized multi-wheeled skateboard assembly including a board deck to support the user, a board having a top side, a bottom side, a flat and a rounded end, linkages, hinges, a steered wheel assembly, an input device and a drive assembly. The steered wheel assembly improves maneuverability, turn radius, and stability. The user steers the skateboard assembly by altering pressure between the top side first end and the top side second end causing the steered wheel to turn, thus manually steering the board. This change in pressure is also altered between the first linkage and second linkage in direct or inverse relation to altering pressure between the top side first end and the top side second end of the board deck. |
US11406889B1 |
Cupholder for snowboard
The cupholder for snowboard is configured for use with a snowboard. The snowboard further comprises a binding. The cupholder for snowboard is a containment structure. The cupholder for snowboard attaches to the binding of the snowboard. The cupholder for snowboard is configured for use with a beverage. The cupholder for snowboard stores the beverage during the use of the snowboard. The cupholder for snowboard comprises the snowboard and containment apparatus. The containment apparatus attaches to the binding of the snowboard. The containment apparatus stores the beverage. |
US11406888B2 |
Additive printing of an airway and oxygen enhancement mouthpiece
The present disclosure relates to systems and methods for manufacturing a mouthpiece with desired dimensions or thicknesses that may enhance the performance of an individual when participating in a contact sport. Mouthpieces and methods consistent with the present disclosure may include incremental steps of three dimensional printing that use different materials. Dimensions and materials used when manufacturing mouthpieces of the present disclosure may be optimized according to user preferences or settings. |
US11406885B2 |
Portable electronic devices
A variety of improvements to portable electronic devices are disclosed, particularly electronic devices designed for use in and around water. The improvements include a more secure interface jack, improved waterproofing techniques, improved battery stability, and improved device functionality. One or more of the disclosed improvements may be incorporated into a variety of portable electronic devices. |
US11406880B1 |
Systems and methods for a variable thickness club head
A method for forming a crownplate of a golf club head includes the steps of providing a first plurality of composite pre-preg plies, aligning the first plurality of pre-preg plies within a mold cavity in a first configuration in the shape of the crownplate, and heating the plurality of composite pre-preg plies to form the crownplate. The first configuration includes a first thickness area and a second thickness area. The second thickness area is thicker than the first thickness area. |
US11406877B1 |
Golf ball cover with silane coupling agent
A golf ball with a cover layer composed of a blend of non- or partially neutralized copolymeric or terpolymeric ionomer(s), hydroxyl-functionalized styrenic block copolymer and silane coupling agent (SCA). The amount of SCA is preferably between 0.01 and 2.0 weight percent based on the total weight of the polymer composition. The cover layer preferably has a Shore A hardness less than 90. |
US11406875B2 |
Sports apparatus
The invention relates to sports apparatuses with unstable surface intended for improving and maintaining ones physical condition. The sports apparatus according to a first embodiment comprises a flexible shell formed as a hermetic chamber with a valve and having an inner space for filling with a filler material and/or air. The hermetic chamber is accommodated within a case with handles. Once the chamber inner space is filled with a filler material and/or air, the sports apparatus in fact forms a rectangular parallelepiped with rounded corners. Side faces of the apparatus form a closed surface. The side face has a height not exceeding a half of the apparatus length. A supporting portion of the apparatus and a portion that the user interacts with are arranged to be identical and outwardly convex. The sports apparatus in operating condition has an elliptical cross-section. Said sports apparatus portions are unstable surfaces. |
US11406873B2 |
Timeline and media controller for exercise machine
A program is presented to a user including a stream of content including a first auditory content and a first visual content related to the workout. A context state of the user participating in the workout is determined based on information from a sensor. A responsive content is selectively added based on the context state of the user to the stream of content in a manner that avoids conflict with the stream of content. |
US11406867B1 |
Portable system and apparatus for dynamometry, exercise, and rehabilitation
A portable system for dynamometry, exercise, and rehabilitation comprises a base, a detachable servomotor assembly, an embedded control system, and a physical human-machine interface for securing a human limb into a stabilized position for use in a repeatable and ambidextrous manner. In another embodiment, the portable system includes a power source and a user interface subsystem for selecting operative modes and input parameters and for real-time processing, display, and storage of the values collected by the system during operation. In another embodiment, a method for determining strength of an isolated muscle group of a human joint is disclosed. The method includes the steps of mounting and securing a detachable servomotor assembly of a portable dynamometer upon a surface and securing the human joint to be tested into a stable position with an adjustable, ambidextrous distal limb attachment assembly for use of the portable dynamometer in a readily repeatable manner. |
US11406866B2 |
Exercise device for deep squat and body stretch
An exercise device for deep squat and body stretch has a device body, a damping assembly, and a pedal set. The device body has a base. The damping assembly is disposed on the base, and has a tube, a pneumatic cylinder which has multiple positioning through holes, and a seat. The pneumatic cylinder is mounted in the tube. An adjusting component is able to extend through the tube and is mounted with one of the positioning through holes. The seat is connected to the pneumatic cylinder for height adjustment. The pedal set is assembled on the device body, and has two pedals rotatably mounted on the device body. |
US11406864B2 |
Exercise machine inclination device
An exercise machine inclination device for providing variable exercise intensity on an exercise machine by inclining the exercise machine. The exercise machine inclination device generally includes a base adapted for being positioned upon a floor, a support structure adapted for supporting the exercise machine, a hinge pivotally connecting the base and the support structure and an actuator connected between the base and the support structure, wherein the actuator adjusts an angle of the support structure. |
US11406859B2 |
Gait pattern training device
A gait trainer adapted for use with a treadmill and, optionally, a spinning cycle, provides greater accessibility for therapeutic and rehabilitative gait pattern training to individuals confronting injury, illness, or disability. The gait trainer is adjustable, to accommodate a wide variety of users with different stride lengths and needs. |
US11406856B2 |
Fire extinguishing system valve
A fire-extinguishing-system valve (2) having a housing (4), having a fluid-entry chamber (26) provided in the housing (4), having a fluid-exit chamber (24) provided in the housing (4), and having a closing body (28) which can be moved back and forth between a blocking state (32) and a release state (34) and, in the blocking state (32) prevents direct fluid flow between the fluid-entry chamber (26) and the fluid-exit chamber (24) and, in the release position (34), connects the fluid-entry chamber (26) to the fluid-exit chamber (24) directly for fluid-conducting action. The fire-extinguishing-system valve (2) has at least one sensor device (18) for directly monitoring the position of the closing body (28). |
US11406855B2 |
Dynamic fire suppression system and method i'hereof
A fire suppression system having a first triggering mechanism capable of being remotely triggered in response to a fire condition and a second manual triggering mechanism. More particularly, the fire extinguisher includes a valve for a fire extinguisher capable of manual and automatic operation. The system further includes a mechanism to notify of inoperable local status. During automatic operation, the system can be being triggered by a control panel in electrical communication, such as in response to a signal from smoke detectors. This system may also be manually triggered or in response to a temperature threshold sensor or other sensors. The valve includes an actuator that provides a separate area to place a safety pin for storing securely, and which provides feedback to the control system that the safety pin is properly stored and therefore, the fire extinguisher is active. |
US11406854B2 |
System, apparatus and method for arresting propagation of a deflagration in a clean air return duct of an air-material separator
Disclosed herein are a system, method, and apparatus for arresting flames in an air return line. The apparatus includes a flame barrier containing one or more metal mesh layers and configured to permit airflow there through while preventing flame break-through. The flame barrier can also have or be connected to one or more temperature or pressure sensors configured to detect blockage of airflow through the flame barrier and to detect damage to the flame barrier. The apparatus can also include additional temperature or pressure sensors for detecting the propagation of deflagration in the air return line. |
US11406848B2 |
Ultrasonic therapy device using HIFU and control method thereof
The present disclosure relates to an ultrasound therapy device using high-intensity focused ultrasound (HIFU) and a control method thereof. The ultrasound therapy device comprises: an array type HIFU converter having a plurality of HIFU conversion elements; and a control unit for performing a control to treat tissues in a focusing area by selecting and driving some of the HIFU conversion elements of the array type HIFU converter and irradiating ultrasound signals to an object through the driven active conversion elements to generate heat energy, wherein, after an elapse of a predetermined time period, the control unit drives a combination of other conversion elements as new active conversion elements in replacement of the active conversion elements. |
US11406847B2 |
Proton linear accelerator system for irradiating tissue with two or more RF sources
Proton beams are a promising alternative to X-rays for therapeutic purposes because they may also destroy cancer cells, but with a greatly reduced damage to healthy tissue. The energy dose in tissue may be concentrated at the tumor site by configuring the beam to position the Bragg Peak proximate the tumor. The longitudinal range of a proton beam in tissue is generally dependent upon the energy of the beam. However, after switching energies, the proton-beam system requires some time for the beam energy to stabilize before it may be used for therapy. A proton linear accelerator system is provided for irradiating tissue with an improved beam energy control, configured to provide RF energy from a first RF energy source during the on-time of the proton beam operating cycle for changing the energy of the proton beam, and to provide RF energy from a second distinct RF energy source during the off-time of the proton beam operating cycle for increasing or maintaining the temperature of the cavity. Each RF source is operated independently, allowing higher RF pulse rates to reach the cavity, supporting a smaller time between proton beam energy pulses. In addition, the peak power requirements for the second RF energy source may, in general, be less than for the second RF energy source, allowing a less costly type to be used for the second source. The use of a first and second RF source may reduce the cavity settling time from minutes to less than 10 seconds. |
US11406844B2 |
Method and apparatus to derive and utilize virtual volumetric structures for predicting potential collisions when administering therapeutic radiation
A control circuit accesses topograms of a patient that include patient content that is beyond the portion of the patient that appears in the three-dimensional computed tomography (CT) images for that patient. The control circuit uses those topograms to derive a virtual volumetric structure representing at least some of the patient content that is beyond the aforementioned portion of the patient that appears in the 3D CT images. That virtual volumetric structure can then be used to predict potential collisions when assessing a radiation treatment plan for the patient that utilizes the aforementioned radiation treatment platform. By one approach the topograms include at least two substantially orthographic views of the aforementioned patient content. |
US11406842B2 |
Garment including therapeutic light source
A garment includes a fabric base layer and at least one side-emitting optical fiber retained to or integrated with the fabric base layer. The fabric base layer can stretch in the grain and cross grain direction of the fabric base layer. The at least one side-emitting optical fiber is located in at least one light-emitting zone to be located over a targeted body area of the person wearing the garment, and is configured to receive light from a light source and in the at least one light-emitting zone is configured to project light having a therapeutic wavelength toward the targeted body area. |
US11406840B2 |
Systems and methods for reducing the viscosity of blood, suppressing turbulence in blood circulation, and curing Rouleaux
Systems and methods for reducing blood viscosity along a flow direction, suppressing turbulence in blood flow, and treating rouleaux are disclosed. One method includes applying a unidirectional magnetic field to a flow of blood in a direction parallel or antiparallel to a direction of the flow of blood, and maintaining the application of the unidirectional magnetic field to the flow of blood until a blood viscosity along the direction of the flow of blood is reduced and/or the turbulence in the blood flow is suppressed. One system includes an annular magnet sized to encircle a portion of a patient's body. The magnet is adapted to generate a unidirectional magnetic field in a region within the annular magnet. The unidirectional magnetic field has a strength sufficient to reduce the blood viscosity in the portion of the patient's body and/or suppress turbulence in the blood flow by a predetermined amount. The system will also break rouleaux for patients with rouleaux, but the process will take more time. The blood viscosity reduction and turbulence suppression can make the blood flow laminar, lower the patient's blood pressure, cure hypertension, diminish heart murmur, and prevent development of astherosclerosis plaque in blood vessels. The curing rouleaux will improve the patient's blood oxygen function. |
US11406838B2 |
Extra-cardiovascular cardiac pacing system for delivering composite pacing pulses
An implantable medical device is configured to control a therapy module to couple a capacitor array comprising a plurality of capacitors to a plurality of extra-cardiovascular electrodes and control the therapy module to deliver a composite pacing pulse to a patient's heart via the plurality of extra-cardiovascular electrodes by sequentially discharging at least a portion of the plurality capacitors to produce a series of at least two individual pulses that define the composite pacing pulse. |
US11406837B2 |
Defibrillator providing cardio pulmonary resuscitation feedback
A defibrillator assesses cardio pulmonary resuscitation carried out on a subject and provides feedback. The defibrillator measures bio signals of the subject, determines when CPR is required and produces a start signal and determines and when CPR is no longer required and produces a stop signal. A measurement system measures compression signals during CPR chest compressions, a CPR assessment system receives the CPR start signal and the CPR stop signal and receives compression signals. The defibrillator uses the compression signals to establish a first CPR performance measurement, set a performance baseline of the person equal to the first CPR performance measurement of the person, compare the further CPR performance measurement of the person with the CPR performance baseline of the person, produce a feedback signal and set the CPR performance baseline of the person equal to the further CPR performance measurement of the person and return to earlier operations. |
US11406836B1 |
Wireless power receiver coil for neuromodulation device
The present disclosure relates to implantable neuromodulation devices, and in particular to a wireless power coil in a low profile environment such as with a neurostimulator. Particularly, aspects of the present disclosure are directed to a medical device that comprises a lossy housing surrounding a power supply, and a receiving coil configured to exchange power wirelessly via a wireless power transfer signal and deliver the power to the power supply. The receiving coil is adjacent the lossy housing. The receiving coil is a helical structure with a total rise that is less than or equal to a height of the lossy housing. |
US11406835B2 |
Medical devices and/or lead extensions having fixation structures with retained portions providing medical lead fixation
Medical devices include fixation structures that include retained portions that provide medical lead fixation within the medical devices. Lead extensions include fixation structures that include retained portions that provide medical lead fixation within the lead extensions. A grip that a clinician may grasp and manipulate is engaged with a nose structure of a header block of the medical device or a connector block of a lead extension and manipulation of the grip causes compression of a deformable structure to ultimately create fixation of the lead or lead extension within the header block or the lead within the extension connector block. The deformable structure may be the retained portion of the fixation structure or alternatively may be separate from the fixation structure. |
US11406832B2 |
Patient-intermediated therapy management
In some examples, controlling delivery of therapy includes using an implantable medical device comprising at least one electrode. Processing circuitry of a system comprising the device may receive, from an application running on a patient personal device, a patient request entered by the patient into the application. The processing circuitry may further determine, based on the patient request, a requested value of a therapy parameter, compare the requested value to information stored in a memory of the medical device system, the information indicating one or more allowable values of the therapy parameter, determine that the requested value is one of the allowable values based on the comparison of the requested value of the therapy parameter to the one or more allowable values, and control the implantable medical device to deliver cardiac pacing via the at least one electrode according to the requested value for a period of time. |
US11406829B2 |
Cardiac stimulation apparatus and method for the control of hypertension
A method that electrically stimulates a heart muscle to alter the ejection profile of the heart, to control the mechanical function of the heart and reduce the observed blood pressure of the patient. The therapy may be invoked by an implantable blood pressure sensor associated with a pacemaker like device. In some cases, where a measured pretreatment blood pressure exceeds a treatment threshold, a patient's heart may be stimulated with an electrical stimulus timed relative to the patient's cardiac ejection cycle. This is done to cause dyssynchrony between at least two cardiac chambers or within a cardiac chamber, which alters the patient's cardiac ejection profile from a pretreatment cardiac ejection profile. This has the effect of reducing the patient's blood pressure from the measured pretreatment blood pressure. |
US11406826B2 |
Methods and systems for optimizing selection and placement of cochlear implant electrode arrays using patient-specific cochlear information and applications of same
A method for using information of patient-specific cochlea size and/or shape to determine a patient-customized cochlear implant electrode insertion and placement plan includes segmenting shapes of structures of interest (SOIs) of the cochlea in a pre-operative CT image of the cochlea using a shape model; defining a 3D modiolar hugging curve within the shape model of the SOIs as a sequence of points; automatically transforming the defined 3D modiolar hugging curve to the pre-operative CT image so as to obtain a modiolar curve in the cochlea; rigidly registering an EA shape model of the EA to the modiolar curve in the cochlea, thereby placing a resting state shape of the EA within the patient's SOIs such that the EA matches the modiolar curve in the cochlea; and determining a patient-customized insertion plan for electrode placement using the registered EA shape model. |
US11406825B2 |
Mobile phone for treating a patient with dementia
Devices, systems and methods are disclosed that allow a patient to self-treat neurodegenerative diseases, such as dementia, Alzheimer's disease, ischemic stroke, post-concussion syndrome, chronic traumatic encephalopathy and the like by electrical noninvasive stimulation of a vagus nerve. The system comprises a handheld stimulator that is applied to the surface of the patient's neck, wherein the stimulator comprises or is joined to a smartphone. A camera of the smartphone may be used to position and reposition the stimulator to a particular location on the patient's neck. The system may also comprise a base station that is used to meter the charging of a rechargeable battery within the stimulator. The base station and stimulator transmit data to one another regarding the status of a stimulation session. |
US11406818B2 |
Tissue-penetrating electrochemical sensor featuring a co-electrodeposited thin film comprised of polymer and bio-recognition element
A method and device to impart the ability to selectively quantify chemical/biochemical analytes occupying physiological fluids via an automated process that allow the precise and spatially-defined simultaneous deposition of a thin-film of polymer containing an immobilized biorecognition element dispersed therein. A tissue penetrating electrochemical sensor comprises at least one working electrode and at least one of a reference electrode and a counter electrode. |
US11406817B2 |
Low equivalent series resistance RF filter circuit board for an active implantable medical device
A filtered feedthrough assembly includes a ferrule configured to be installed in an AIMD housing. An insulator is disposed within a ferrule opening. A conductive pathway is disposed within a passageway through the insulator. A filter capacitor is disposed on a device side having active and ground electrode plates disposed within a capacitor dielectric k greater than 0 and less than 1,000. A capacitor active metallization is electrically connected to the active electrode plates. A ground capacitor metallization is electrically connected to the ground electrode plates. The filter capacitor is the first filter capacitor electrically connected to the conductive pathway coming from a body fluid side into the device side. An active electrical connection electrically connects the conductive pathway to the capacitor active metallization. A ground electrical connection electrically connects the ground capacitor metallization to the ferrule. The filter capacitor is a flat-through or an X2Y attenuator filter capacitor. |
US11406813B2 |
Stimulation probe assemblies and methods of use
Aspects of the disclosure include a bio-electric stimulation probe assembly including a patch including a first aperture and also a guide socket including a grommet and a second aperture. The guide socket is positioned on the patch such that the first and second apertures are aligned. The assembly further includes a guide including a tip that is positioned within and rotatable within the grommet. A probe of the assembly having at least one electrode is interconnected with the guide and extends through the first and second apertures. The guide and guide socket are collectively arranged and configured so that the guide has three degrees of rotational freedom with respect to the grommet thus meaning the probe correspondingly has three degrees of rotational freedom with respect to the grommet. Methods of using stimulation probe assemblies are also disclosed. |
US11406805B2 |
Systems and methods for cross-linking treatments of an eye
Example eye treatments determine an area at a surface of a cornea for delivery of a cross-linking agent. The example treatments disrupt tissue at the area at the surface of the cornea up to a depth corresponding to apical layers of superficial squamous cells of the cornea, e.g., no greater than approximately 10 μm to approximately 15 μm. The example treatments apply a cross-linking agent to the area at the surface of the cornea. The cross-linking agent is transmitted through the disrupted area at a greater rate relative to non disrupted areas of the cornea. The example treatments deliver photoactivating light to the cornea. The photoactivating light activates the cross-linking agent to generate cross-linking activity in the cornea. |
US11406804B2 |
Liquid medicine supply device
A medical liquid supply device that includes: a container including a containing portion with a mouth (16); an interior cap (30); and an exterior cap (60). The interior and exterior caps (30, 60) include a ratchet mechanism (50, 80). The interior cap (30) includes: an interior-cap main body (32) and an interior-cap protrusion (54). The interior-cap main body (32) includes a contact ring (44). The exterior cap (60) includes: an exterior-cap main body (62); and an exterior-cap protrusion (84) configured to be engaged with the interior-cap protrusion (54). The contact ring (44) is distant from the interior-cap protrusion (54) in the radial direction of the interior-cap main body (32). |
US11406802B2 |
Stent trimming devices and methods
Devices and methods for trimming a stent to a desired length with an outer tube and an inner tube having a distal end and a diameter configured to receive a portion of the stent in excess of the desired length. The inner tube may move within the outer tube and the distal end may include an end effector configured to trim the portion from the stent while the device and stent are within a patient. |
US11406794B2 |
Needle hub and IV catheter system comprising such needle hub
An intravenous (IV) catheter system may include a catheter hub, a needle hub and a needle shield. The needle hub may include a needle having a high friction surface part. Furthermore, embodiments may include an open and closed IV catheter system. Embodiments may include a needle hub and a shielded needle system. |
US11406792B2 |
Antifouling urinary catheters with shape-memory topographic patterns
A system of topographic patterns for the prevention of bacterial adhesion and biofilm formation. The patterns may be provided on the surfaces of certain devices that are prone to bacterial adhesion and biofilm formation, such as urinary catheters. To reduce bacterial adhesion and biofilm formation, and to remove existing biofilms, the patterns are induced to transform from a first topography to a second topography. For example, the surface patterns may be formed from a shape memory polymer and then heated to transform the patterns from the first topography to the second topography to dislodge bacteria and prevent fouling. |
US11406786B2 |
Nebulizer monitoring device, system and method
Described herein are devices, systems and methods for monitoring the use of a nebulized medication, such as can be administered using a nebulizer. These can be used for monitoring a patient undergoing treatment for COPD and improve compliance to the recommended therapy. Monitored parameters include flow, humidity and acceleration and provide data as to the quantity and quality of nebulizer use. |
US11406778B2 |
Unlocking a respiratory mode
A system to configure respiratory therapy modes for users of respiratory therapy devices comprises one or more processors configured to execute computer program modules. The modules include a data gathering module for receiving usage information related to a respiratory therapy device in a first therapy mode, an analysis module for determining effectiveness information related to effectiveness of therapy, a provider interface module configured for receiving a first unlock selection based on the determined effectiveness information, the first unlock selection being received while the respiratory therapy device is operating in the first therapy mode, the first unlock selection indicating that a second therapy mode for the respiratory therapy device should be unlocked, and a device configuration module configured such that, responsive to reception of the first unlock selection by the provider interface module, the device configuration module activates the second therapy mode for the respiratory therapy device. |
US11406776B2 |
Life support and monitoring apparatus with malfunction correction guidance
A life support and monitoring apparatus with malfunction correction guidance is provided. The life support and monitoring apparatus of the present disclosure identifies the root cause or potential cause of a fault/failure and then prompts an operator to take appropriate steps to assure the continuance of life support and critical physiologic monitoring. When multiple faults/failures exist, the apparatus automatically prioritizes them based on risk to the patient and prompts the operator to do the most appropriate intervention to assure patient safety. |
US11406771B2 |
Apparatuses and methods for delivering powdered agents
In one aspect of the present disclosure, an apparatus for delivering a powdered agent into a subject's body may include a powder chamber housing the powdered agent. The apparatus also may include a chassis in fluid connection with the powder chamber. The chassis may include a first passage for receiving a pressurized gas, a second passage for receiving the powdered agent from the powder chamber, and a junction in fluid communication with the first passage and the second passage. At least a first portion of the pressurized gas is introduced into the powdered agent at the junction to fluidize the powdered agent. |
US11406769B2 |
Lubrication of an injection needle
A method for lubricating an injection needle when used multiple times at a single occasion to penetrate a support, the method including the steps of: a) depositing a layer of a lubricating composition on the support; b) penetrating multiple times the layer of the lubricating composition deposited in step a) with the injection needle, thereby providing a lubricated injection needle having a deposited layer of the lubricating composition thereon. |
US11406766B2 |
Applicator system and method for flowable compositions
Described are applicators having a plunger with a plunger body, and a tube having a receptacle end for insertion of the plunger, and a connector end formed of flexible plastic material having a bull-nose shape. As an example, the plunger body can include a viewing window. As another example, the connector end has an internal surface that is free of threaded connectors. The connector end can also have a snap-fit coupling design to couple to a snap-fit nozzle. The snap-fit nozzle can be connected to an adaptor cap or an administering tool of a metering dispenser. |
US11406760B2 |
Auto injector with charger safety
An auto injector is disclosed comprising: a housing, a cartridge receiver, and an ejector member. The cartridge receiver is configured to receive a cartridge containing the medicament. The auto injector further comprises a blocking member coupled to an ejector member. The blocking member is configured to move between a blocking position wherein a connector opening is blocked and a non-blocking position wherein the connector opening is not blocked. |
US11406759B2 |
Method and devices for pressure determination in an insulin pump
A method for connecting a force sensor to a circuit board is disclosed. A circuit board having first and second conductive leads located on the same surface of the circuit board is provided. Also provided is a force sensor with a first flexible contact tab having a first contact pad and a second flexible contact tab having a second contact pad. The first contact pad is arranged to face the first conductive lead. A first conductive rubber element establishes an electrical connection between the first contact pad and the first conductive lead, and the second contact pad and the second conductive lead are arranged to face in the same direction. A second conductive rubber element establishes an electrical connection between the second contact pad and the second conductive lead. Also disclosed are an associated device for determining fluid pressure in an insulin pump and an insulin pump. |
US11406757B2 |
Controller and method for refilling a dosing unit
Disclosed is a method for scheduling a refilling of a secondary reservoir of an ambulatory infusion system out of a primary reservoir storing a liquid drug. The method includes repeatedly and automatically carrying out a filling volume assessment routine. The filling volume assessment routine includes: determining, at a present point in time, an estimated filling volume of the secondary reservoir at a future estimation point in time, the future point in time being an estimation time interval after the present point in time, and determining in dependence of the estimated filling volume, if the secondary reservoir shall be refilled at the present point in time. |
US11406755B1 |
Sensing fluid flow irregularities in an on-body injector
An on-body injector includes a drug reservoir with an associated temperature sensor. A piston having an associated force sensor is driven to convey a drug out of the drug reservoir during a drug delivery routine. The temperature and force sensors are electrically coupled to a controller that controls the components of the on-body injector to execute a drug delivery routine. The controller receives signals from the temperature sensor indicative of a temperature of the drug within the reservoir and from the force sensor indicative of a force experienced by the piston during the drug delivery routine. The controller analyzes the signals to determine whether the measured force is different from an expected force at the measured temperature. The controller generates an error signal when the measured force is different from the expected force at the measured temperature. |
US11406752B2 |
Extensible infusion devices and related methods
Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a user in accordance with an operating mode involves identifying a fluid type associated with the fluid currently onboard the infusion device from among a plurality of possible fluid types that is different from a previous type of fluid previously onboard the infusion device. The identified fluid type has pharmacokinetics characteristics that are different from pharmacokinetics characteristics associated with the previous fluid type. The method continues by updating one or more parameters referenced by a control module of the infusion device implementing the operating mode to reflect the pharmacokinetics characteristics associated with the identified fluid type and autonomously operating the infusion device to deliver the fluid of the identified fluid type to the user in accordance with the operating mode and the one or more updated control parameters. |
US11406751B2 |
Determination of a time-dependent contrast agent injection curve as a function of CT scan parameters
A method for the automatic determination of a contrast agent protocol for a contrast agent-enhanced medical imaging method is described. The method includes an overview recording of a region of interest of an object under examination. In addition, an image recording protocol including a plurality of recording parameters is defined on the basis of the overview recording. Furthermore, recording time points are determined for a plurality of z-positions of the region of interest on the basis of the image recording protocol. In addition, the structures acquired with the overview recording are assigned to the recording time points determined. Finally, a contrast agent protocol including the temporal course of a contrast agent injection curve is defined as a function of the acquired structures and the assigned recording time points. A contrast agent protocol determination device is also described, as well as an imaging medicinal device. |
US11406747B2 |
Extracorporeal circulation apparatus and method of discharging bubbles therefrom
An extracorporeal circulation apparatus including a blood circuit including an arterial blood circuit and a venous blood circuit whose proximal ends are connected to a blood purifier, the blood circuit allowing a patient's blood to extracorporeally circulate from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a discharge unit through which a priming solution supplied into the blood circuit is discharged to an outside; a negative-pressure-generating unit that generates a negative pressure in a region of the blood circuit, the region being filled with the priming solution; and a control unit that controls the negative-pressure-generating unit. The control unit executes a priming step in which the priming solution supplied into the blood circuit is discharged through the discharge unit while a flow route in the blood circuit is filled with the priming solution; a negative-pressure-generating step in which, after the priming step, a negative pressure is generated in the region by the negative-pressure-generating unit; and a discharge step in which bubbles in the region subjected to the negative pressure generated in the negative-pressure-generating step are caused to flow and are discharged through the discharge unit. |
US11406746B2 |
User interface for dialysis treatment
A graphical user interface for a medical system comprises a display device, an electronic processor that operates with the display device to display a plurality of screens including a programming screen by which a user can enter or modify medical treatment parameters employed by a machine to perform a medical treatment. When a user modifies a first medical treatment parameter, the processor is programmed to adjust at least one other medical treatment parameters depending on the first medical treatment parameters. |
US11406745B2 |
Balancing method and balancing unit being independent of temperature disturbance
This disclosure relates to a method for determining a fluid balance between a first volume flow in a first section of a fluid circuit and a second volume flow of a second section of the fluid circuit. The method may also include adjusting, assuming or detecting a first temperature in the first section of the fluid circuit and a second temperature in the second section of the fluid circuit, or detecting a temperature difference between the first and the second sections. The method may also include detecting a second volume flow in a second section of the fluid circuit and forming a balance from at least the first volume flow and a corrected value of the second volume flow. The corrected value is determined from the detected second volume flow and the second temperature and/or the temperature difference. |
US11406743B2 |
Substrate having an electron donating surface with metal particles comprising palladium on said surface
There is disclosed a substrate with an electron donating surface, characterized in having metal particles on said surface, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, and platinum, wherein the amount of said metal particles is from about 0.001 to about 8 μg/cm2. Examples of coated objects include contact lenses, pacemakers, pacemaker electrodes, stents, dental implants, rupture nets, rupture mesh, blood centrifuge equipment, surgical instruments, gloves, blood bags, artificial heart valves, central venous catheters, peripheral venous catheters, vascular ports, haemodialysis equipment, peritoneal dialysis equipment, plasmapheresis devices, inhalation drug delivery devices, vascular grafts, arterial grafts, cardiac assist devices, wound dressings, intermittent catheters, ECG electrodes, peripheral stents, bone replacing implants, orthopaedic implants, orthopaedic devices, tissue replacing implants, intraocular lenses, sutures, needles, drug delivery devices, endotracheal tubes, shunts, drains, suction devices, hearing aid devices, urethral medical devices, and artificial blood vessels. |
US11406742B2 |
Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided. |
US11406741B2 |
Odor barrier film
A multilayer film for ostomy and bowel management applications includes a barrier layer comprising at least about 90% wt. nylon 6/69. The multilayer film provides excellent mechanical and odor barrier properties, and softness and quietness desired in ostomy and bowel management applications. |
US11406737B2 |
Gelatin/elastin composites for peripheral nerve repair
Neurosupportive materials that possess strong tissue adhesion were synthesized by photocrosslinking two polymers, gelatin methacryloyl (GelMA) and methacryloyl-substituted tropoelastin (MeTro). The engineered materials exhibited tunable mechanical properties by varying the GelMA/MeTro ratio. In addition, GelMA/MeTro hydrogels exhibited 15-fold higher adhesive strength to nerve tissue ex vivo compared to traditionally used fibrin-based materials. Furthermore, the composites were shown to support Schwann cell (SC) viability and proliferation, as well as neurite extension and glial cell participation in vitro, which are essential cellular components for nerve regeneration. Finally, subcutaneously implanted GelMA/MeTro hydrogels exhibited slower degradation in vivo compared with pure GelMA, indicating its potential to support the growth of slowly regenerating nerves. Thus, GelMA/MeTro composites may be used as clinically relevant biomaterials to regenerate nerves and reduce the need for microsurgical suturing during nerve reconstruction. |
US11406736B2 |
Vascular extracellular matrix hydrogel
Provided herein are methods of making an ECM gel from vascular tissue. Also provided herein are ECM compositions prepared from vascular tissue, and methods of use of those compositions, for example in treatment of aneurysms, and for vascularization or re-vascularization. |
US11406735B2 |
Methods of manufacturing cartilage products
This invention provides porated cartilage products and methods of producing porated cartilage products. Optionally, the cartilage products are sized, porated, and digested to provide a flexible cartilage product. Optionally, the cartilage products comprise viable chondrocytes, bioactive factors such as chondrogenic factors, and a collagen type II matrix. Optionally, the cartilage products are non-immunogenic. |
US11406734B2 |
Malleable demineralized bone composition and method of manufacture
A malleable demineralized bone composition consists of cortical bone made from a first portion and a second portion. The first portion and second portion of cortical bone is made from cut pieces freeze dried then ground into particles and demineralized then freeze-dried. A volume of the second portion is placed in a solution of sterile water to create a mixture, the water volume being seven times the volume of the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, and the first portion is mixed with the gelatin to form a malleable putty or paste. |
US11406733B2 |
Porous microparticles of biodegradable polymer, and polymer filler comprising same
The present invention relates to porous microparticles of a biodegradable polymer, and a polymer filler comprising the same. |
US11406732B2 |
Tunable, controlled-release, urethane-containing elastomers and processes of forming the same
A process forms an implantable product including poly(glycerol sebacate) urethane (PGSU) loaded with an active pharmaceutical ingredient (API). The process includes homogeneously mixing a flowable poly(glycerol sebacate) (PGS) resin with the API and a catalyst to form a resin blend. The process also includes homogeneously combining the resin blend with an isocyanate to form a reaction mixture and injecting the reaction mixture to form the PGSU loaded with the API. An implantable product includes a PGSU loaded with an API. In some embodiments, the implantable product includes at least 40% w/w of the API, and the implantable product releases the API by surface degradation of the PGSU at a predetermined release rate for at least three months under physiological conditions. In some embodiments, the PGSU is formed from a PGS reacted with an isocyanate at an isocyanate-to-hydroxyl stoichiometric (crosslinking) ratio in the range of 1:0.25 to 1:1.25. |
US11406731B2 |
Hygroscopic, crosslinking coatings and bioadhesives
According to the present disclosure, a bioadhesive formulation is provided. The bioadhesive formulation comprises a polycaprolactone dendrimer having a dendrimer core and a plurality of polycaprolactone chains extending from the dendrimer core, wherein at least one of the polycaprolactone chains has an end which is covalently attached with a diazirine, and wherein the diazirine converts to a carbene or a diazoalkyl when a stimulant is applied to the bioadhesive formulation. Methods of forming the bioadhesive formulation are also provided. The bioadhesive could be used in (i) the prevention of thrombosis from tissue fixation and/or (ii) the relief of discomfort and/or pain during and/or after surgery. Preferably, the bioadhesive formulation further comprises a hygroscopic additive, an antithrombotic agent, and/or an anaesthetic agent. |
US11406727B2 |
Endoscope reprocessor
An endoscope reprocessor having a tube and nozzles may be used to increase the effectiveness of an endoscope reprocessor. Fluid may be delivered into the tube through the nozzle, which may be oriented in various orientations. Energy of the flow within the tube may be increased by introduction of fluid through the nozzles, which may additionally move the endoscope within the tube. |
US11406725B2 |
Dual-pass-through countertop high velocity hot air sterilizer
A device and system for sterilizing objects, commonly dental, medical, or veterinary instruments, having a double door configuration that can provide entry of contaminated instruments into a sterilizer from a contaminated area and subsequently, post-sterilization, their pass-through directly into a sterile area through an exit door from said sterilizer. More specifically, the invention is a countertop, high velocity, dry heat sterilization device that is readily adaptable for those clinical areas requiring separation of contaminated and sterile areas for the processing of medical, dental, or veterinary instruments. The sterilization device utilizes a dual airflow pathway and a controlled heat delivery system to deliver to the sterilization chamber the supply air having temperature uniformity and air velocity required of the high velocity dry heat sterilization process. |
US11406724B2 |
Stabilized radiolabeled anti-CD45 immunoglobulin compositions
Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas. |
US11406723B2 |
Radiotherapeutic and companion imaging agents to target MC1R
The subject matter disclosed herein relates generally to cancer therapy and to anti-cancer compounds and imaging agents. More specifically, the subject matter disclosed herein relates to agents that target MC1R and their use in the treatment of cancer. Methods of screening for MC1R targeted agents are also disclosed. |
US11406722B2 |
Nanodroplets with improved properties
Stable perfluorocarbon nanodroplet compositions with properties such as low-boiling points and small particle diameters are provided for improved performance in ultrasound imaging and therapeutic applications. Methods of producing stabilized nanodroplet compositions and methods of using the compositions are further provided to allow for improved performance in ultrasound imaging techniques and/or therapeutic applications. |
US11406716B2 |
Modified RNAi agents
One aspect of the present invention relates to double-stranded RNAi (dsRNA) duplex agent capable of inhibiting the expression of a target gene. The dsRNA duplex comprises one or more motifs of three identical modifications on three consecutive nucleotides in one or both strand, particularly at or near the cleavage site of the strand. Other aspects of the invention relates to pharmaceutical compositions comprising these dsRNA agents suitable for therapeutic use, and methods of inhibiting the expression of a target gene by administering these dsRNA agents, e.g., for the treatment of various disease conditions. |
US11406715B2 |
Methods of treating HER2-positive metastatic breast cancer
Methods of treating patients having HER2-positive, locally advanced or previously untreated metastatic breast cancer having received prior treatment with a taxane using an anti-HER2-maytansinoid conjugate (for example trastuzumab emtansine) are provided. |
US11406713B2 |
Xanthine oxidase inhibitor formulations
Disclosed herein are methods and compositions for involving a xanthine oxidase inhibitor that has enhanced solubility. The compositions described herein include a xanthine oxidase inhibitor combined with an organic base. The compositions can be used to treat a disease or medical condition that involves elevated uric acid levels. |
US11406699B2 |
Alphavirus and compositions, methods, and kits related thereto
The present invention provides modified alphaviruses and compositions, methods, and kits for preparing and using them to elicit an immune response to an alphavirus in a subject. |
US11406694B2 |
Vaccine comprising drug and parasite administration
Apicomplexan parasites or red blood cells infected with apicomplexan parasites are administered to an animal in combination with a delayed death agent that initially allows parasite replication but subsequently kills the apicomplexan parasites. This allows the elicitation of an immune response by the animal while preventing the parasites producing a serious infection of the animal. The apicomplexan parasites may be malaria or babesia parasites. The delayed death agent may be a tetracycline class antibiotic, a macrolide antibiotic or a lincosamide antibiotic. |