Document | Document Title |
---|---|
US11254930B2 |
Methods for targeted insertion of DNA in genes
Methods and compositions for modifying the coding sequence of endogenous genes using rare-cutting endonucleases and transposases. The methods and compositions described herein can be used to modify the coding sequence of endogenous genes. |
US11254929B2 |
Method, substrate and kit for one-pot one-step assembly of DNA molecules
A method for one-pot one-step assembly of two or more DNA molecules to form at least one recombinant DNA molecule, and a substrate and a kit for this purpose. A simple and cost-effective assembly method for DNA molecules. A method for one-pot one-step assembly of two or more DNA molecules to form at least one recombinant DNA molecule is provided, wherein the two or more DNA molecules to be assembled are brought together in dry form with a suitable reaction medium on at least one substrate present in a reaction vessel. |
US11254925B2 |
Enzyme-porous carbon composite
The present invention relates to an enzyme-porous carbon composite, and more specifically, to an enzyme-porous material composite capable of realizing a much higher enzyme adsorption amount than porous silica and maintaining high stability of an immobilized enzyme. |
US11254921B2 |
ADAMTS13 protein cell culture supernatant
The present invention provides culture mediums that are useful for the expression of ADAMTS proteins, such as ADAMTS13. Methods for the expression and purification of ADAMTS proteins are also provided. In some embodiments, the mediums and methods of the invention are useful for the expression of ADAMTS proteins having high specific activities. Also provided are ADAMTS, e.g., ADAMTS13, protein compositions with high specific activities, which are expressed and purified according to the methods provided herein. |
US11254913B1 |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens. |
US11254912B2 |
Methods and compositions for treating cancer
Provided herein, in some embodiments, are methods and compositions (e.g., cell compositions) for the treatment of cancer. The methods and compositions involve genetically engineered immune cells (e.g., T cells), in which the endogenous CD70 gene is disrupted by genetic editing, for example, the CRISPR/Cas9 gene editing technology. |
US11254911B2 |
Generation of neural stem cells from human trophoblast stem cells
Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells. |
US11254908B2 |
Plants containing beneficial endophytes
This application relates to methods and materials for providing a benefit to a seed, seedling or plant by producing seeds that are internally colonized with endophytes. Beneficial endophytes with particular characteristics are provided. These may be used in the methods described to provide a benefit to a seed, seedling or plant. |
US11254906B2 |
Automatic purification system and biological sample purification method
An automatic purification system using magnetic particles comprises: 1) a first container module; and 2) a system controller module. The first container module comprises a first container and a first magnetic field supply device disposed outside the first container. A first container liquid inlet is formed in the upper portion of the first container, and a first container liquid outlet is formed in the bottom of the first container. The system controller module can generate a variable magnetic field in the first container by controlling the first magnetic field supply device. A method for purifying a target component from a biological sample comprises a step for allowing a biological sample containing a target component to be in contact with magnetic particles capable of specifically binding the target component, in the first container in the automatic purification system. The automatic purification system and method help to efficiently separate a target product from a biological sample, and helps to reduce process costs and time at the same time. |
US11254903B2 |
Method and system for suspension culture
The present invention relates to cell culture in bioreactors, such as flexible cellbag bioreactors. More closely the invention relates to a method and system for determining the cell density in a bioreactor culture and for controlling the perfusion rate of a suspension culture of cells in a bioreactor, comprising measuring the oxygen uptake of primary mononuclear cells in a non-static bioreactor. |
US11254901B2 |
System and method for printing tissue
A system and method for printing cells in a medium. A multi-dimensional printer, stably constructed of low-mass parts, can include a computer numerically controlled system that can enable motors driving delivery systems. The motors can include encoders that can enable achieving arbitrary resolution. The motors can drive ballscrews to enable linear motion of delivery systems, and the delivery systems can enable printing of a biological material in a pre-selected pattern in a petri dish. The petri dish can accommodate a medium such as a gel, and can further accommodate a vision system that can detect actual position and deflection of the delivery system needle. The printer can accommodate multiple delivery systems and therefore multiple needles of various sizes. |
US11254899B2 |
Maturation container for spirits and method of constructing same
A maturation container and method of maturing spirits that incorporates a polymeric material (10) into a wall of the container. The material (10) is preferably Polylactic Acid (PLA) which has known oxygen permeation properties suited to maturation but is substantially impermeable to ethanol. Use of such a material is proposed to supplement or replace traditional wooden barrel methods of storage. |
US11254897B2 |
Hard surface cleaning compositions
Cleaning compositions that include a non-functionalized alkyl polyglycoside, a nonionic surfactant system, and water. In certain embodiments, the cleaning compositions are substantially free of alkyl phenol ethoxylates. Additionally, some embodiments of the invention are substantially free of butyl cellosolve. The cleaning composition is capable of removing both proteinaceous food soils and hydrocarbon-based oily soils. The cleaning compositions include a biorenewable, environmentally friendly alternative to nonyl phenol ethoxylates and exhibit superior cleaning of food soils. |
US11254894B2 |
Conveyor lubricants including emulsion of a lipophilic compound and an emulsifier and/or an anionic surfactant and methods employing them
The present invention relates to conveyor lubricant compositions including an emulsion of a lipophilic compound and also including an emulsifier and/or an anionic surfactant. The present invention also relates to methods employing such lubricant compositions. In an embodiment, the method includes applying the present lubricant composition to a conveyor with a non-energized nozzle. |
US11254893B2 |
Lubricating composition
A hydraulic lubricating oil composition is provided which contains a synergistic mixture of three phosphorous antiwear components in order to provide good thermal stability and good demulsibility to the lubricating oil composition. |
US11254887B1 |
Separating sweet gas from a sour gas stream
An oxidation-reduction desulfurization system includes a reactor vessel with sour gas inlet at the bottom and a gas outlet at the top. A primary stage phase separator includes a vertically-oriented pipe with an inlet located inside the reactor vessel. The ratio of the reactor vessel diameter to the pipe inlet diameter is in a range of 2:1 to 5:1. Surface foam and non-gaseous multi-phase mixture including emulsion flow into a partially gas-filled upper section of the vertically-oriented pipe and freefall to a lower level, thereby facilitating mechanical breaking of the foam and the emulsion. A secondary stage phase separator connected to the gas outlet separates non-gaseous surge from sweet gas. Valves and a controller automatically maintain target levels of the non-gaseous multi-phase mixture and non-gaseous surge. |
US11254884B2 |
Fuel comprising ketone(s)
Provided are fuel components, a method for producing fuel components, use of the fuel components and fuel containing the fuel components based on ketone(s). |
US11254864B2 |
Films with narrow band emission phosphor materials
A color conversion film is provided. The film includes at least one narrow band emission phosphor dispersed within a binder matrix, wherein the narrow band emission phosphor has a D50 particle size from about 0.1 μm to about 15 μm and is selected from the group consisting of a green-emitting U6+-containing phosphor, a green-emitting Mn2+-containing phosphor, a red-emitting phosphor based on complex fluoride materials activated by Mn4+, and a mixture thereof. A device is also provided. |
US11254861B2 |
Delivery system for oil-soluble well treatment agents and methods of using the same
A system for slowly releasing an oil-soluble well treatment agent into a well or a subterranean formation includes a composite of the oil-soluble well treatment agent associated with a second component. The amount of the oil-soluble well treatment agent in the composite is from 20 to 35 weight percent and the average particle size of the oil-soluble well treatment agent in the composite is less than or equal to 1 micrometer. The composite may further contain a water-soluble well treatment agent. |
US11254860B2 |
Diversion using solid particulates
A method may comprise: introducing a treatment fluid into a wellbore penetrating a subterranean formation wherein the treatment fluid comprises a base fluid; a carbonate compound, wherein the carbonate compound at least partially plugs a zone in the subterranean formation; and an acid; and diverting at least a portion of the treatment fluid and/or a subsequently introduced fluid away from the zone. |
US11254851B2 |
Vulcanized rubber and date tree based lost circulation material (LCM) blend
A vulcanized rubber and date tree based lost circulation material (LCM) is provided. The vulcanized rubber and date tree based LCM includes vulcanized rubber particles, date tree seed particles produced from date tree seeds, and date tree fibers produced from date tree waste. The LCM may include vulcanized rubber particles in the range of 20 pounds-per-barrel (ppb) to 40 ppb in the drilling fluid, date tree seed particles in the range of 50 ppb to 70 ppb in the drilling fluid, and date tree fibers in the range of 10 ppb to 40 ppb in a drilling fluid, including a first size of fibers in the range of 5 ppb to 20 ppb, and a second size of fibers in the range of 5 ppb to 20 ppb. Methods of lost circulation control and manufacture of the vulcanized rubber and date tree based LCM are also provided. |
US11254846B2 |
Two part adhesive composition
The present disclosure relates to an acrylic adhesive composition exhibiting excellent lap shear strength and adhesive strength by including an adhesion enhancer of a specific component. |
US11254845B2 |
Adhesive composition and method for preparing same
Provided is an adhesive composition including lysine, itaconic acid, and water, wherein the lysine and the itaconic acid are present in the form of an aqueous solution of a salt such that precipitates are not formed in the aqueous solution. In addition, provided is a method of preparing an adhesive composition including mixing lysine, itaconic acid, and water to thereby form a mixture of the lysine, the citric acid, and the water, and stirring the mixture at a temperature of 80° C. or less, wherein amounts of the lysine, the itaconic acid, and the water are adjusted such that precipitates of the lysine and the itaconic acid do not form in the adhesive composition. |
US11254841B2 |
Additive manufacturing methods for adhesives and adhesive articles
A method of making an adhesive is provided, including obtaining an actinic radiation-polymerizable adhesive precursor composition disposed against a surface of an actinic radiation-transparent substrate and irradiating a first portion of the actinic radiation-polymerizable adhesive precursor composition through the actinic radiation-transparent substrate for a first irradiation dosage. The method further includes irradiating a second portion of the actinic radiation-polymerizable adhesive precursor composition through the actinic radiation-transparent substrate for a second irradiation dosage. The first portion and the second portion are adjacent to or overlapping with each other and the first irradiation dosage and the second irradiation dosage are not the same. The method forms an integral adhesive having a variable thickness in an axis normal to the surface of the actinic radiation-transparent substrate. Also, an adhesive article is provided, including a substrate having a major surface and an integral adhesive disposed on the major surface of the substrate. |
US11254831B2 |
Encapsulated oligomeric blocked isocyanates
An aqueous dispersion of a capsule is composed of a polymeric shell surrounding a core, the core containing an oligomeric blocked isocyanate characterized in that the blocked isocyanate is derived from a di-, tri- or tetrafunctional isocyanate terminated oligomer selected from the group of an isocyanate terminated oligo-ether, an isocyanate terminated oligo-ester, an isocyanate terminated oligo-carbonate, an isocyanate terminated butadiene oligomer, an isocyanate terminated hydrogenated butadiene, an isocyanate terminated isoprene oligomer, an isocyanate terminated silicone and combinations thereof. The dispersion is suitable for pre-treatment liquids and inkjet inks in textile printing. |
US11254829B2 |
Non-aqueous ink compositions
The present disclosure is drawn to non-aqueous ink compositions. The non-aqueous ink compositions can include from 70 wt % to 98 wt % alcohol solvent, from 1 wt % to 6 wt % phenol-formaldehyde resin, from 1 wt % to 5 wt % tackifier, and from 1 wt % to 14 wt % organic solvent-soluble dye. The tackifier can include a shellac having an acid number from 50 KOH/g to 100 mg KOH/g or a tackifier resin having an acid number from 100 mg KOH/g to 300 mg KOH/g. |
US11254828B2 |
Gravure printing method
The present invention relates to a gravure printing method of conducting printing on a printing substrate with an aqueous ink reserved in an ink pan using a furnisher roll, a gravure roll, a doctor blade and a nip roll, in which the aqueous ink contains a pigment, a polymer, an organic solvent, a surfactant and water; a content of organic solvent components of the organic solvent which have a boiling point of 100 to 260° C. in the aqueous ink is not less than 0.3% by mass and not more than 12% by mass; an average particle size of particles of the pigment is from 120 to 350 nm; and an arithmetic mean roughness (Ra) of a plate surface of the gravure roll is from 10 to 140 nm. According to the present invention, it is possible to improve transfer properties of the ink to the printing substrate such as a resin film, etc., and suppress fogging on the plate surface. |
US11254824B2 |
Solvent composition, cleaning method, method for producing substrate with coating film, and heat transfer fluid
To provide a solvent composition in which various organic substances are soluble, and which has no adverse effect on global environment. A solvent composition comprising 1-chloro-2,3,3,4,4,5,5-heptafluoro-1-pentene, a cleaning method using the solvent composition, a method for producing a substrate with a coating film, and a heat transfer fluid. |
US11254823B2 |
Antifouling coating material composition, antifouling coating film, substrate provided with antifouling coating film and production method therefor, and antifouling method
An object of the present invention is to provide an antifouling coating composition capable of forming an antifouling coating film that retains a high antifouling performance for a prolonged period of time and has an excellent damage resistance. Another object of the present invention is to provide an antifouling coating film formed with the antifouling coating composition, a substrate with an antifouling coating film and a method for producing the same, and an antifouling method using the antifouling coating film. The antifouling coating composition of the present invention contains a hydrolyzable polymer (A) containing a metal ester group, zinc oxide (B), and medetomidine (C), and has a content of the zinc oxide (B) in a solid content of the antifouling composition of 27 to 60% by mass. |
US11254819B2 |
Curing agent mixture
A curing agent mixture is for coatings that cure at room temperature. The curing agent mixture can include (A) 10-60% by weight, preferably 20-60% by weight, more preferably 30-50% by weight, of a polysiloxane, (B) 40-90% by weight, preferably 40-80% by weight, more preferably 40-70% by weight, of an amino-functional alkoxysilane and (C) 1-10% by weight, preferably 2-7% by weight, more preferably 3-5% by weight, of a guanidine compound. The stated amounts of components (A), (B), and (C) add up to 100% by weight and are based on the curing agent mixture. |
US11254817B2 |
Polyurethane composite material, article comprising the material and method of manufacture
The present disclosure relates generally to polyurethane matrix composite materials, for example, suitable for making an exterior cladding product for houses and other buildings. The present disclosure relates more particularly to a polymer matrix composite material including a polyurethane matrix and an inorganic filler in a range from 45% to 85% by weight of the composite material. The inorganic filler includes a first substance from the group consisting of calcium carbonate, sand, talc, kaolin clay, dolomite, feldspar and mica and any mixture thereof, and fly ash, and/or an iron oxide in a range from 0.5% to 7% by weight of the inorganic filler. |
US11254816B2 |
Melt-processable composition
The invention pertains to composition of fluoroplastic and poly(aryletherketone), to method of making the same, and to shaped products therefrom, including notably wire sheaths, which combine advantageous performances of both ingredients, which can be easily manufactured through conventional equipment's, and which notably deliver room temperature toughness, in combination with notably chemical resistance and dielectric properties of fluoroplastics and with mechanical performances of poly(aryl ether ketone)s. |
US11254815B2 |
Polyolefin polylactic acid polymer blends
The invention relates to a process of preparing a polyolefin polylactic acid polymer blend comprising the steps of i) providing a polyolefin selected from polyethylene, polypropylene, and mixtures and copolymers thereof, ii) providing polylactic acid, iii) providing a polyolefin selected from polyethylene, polypropylene, and mixtures and copolymers thereof grafted with at least one epoxide-functional monomer, iv) providing a polylactic acid grafted with at least one carboxylic acid or carboxylic anhydride functional monomer, v) mixing the components i) to iv) at elevated temperature in a range from 150° C. to 260° C., and wherein component i) is provided in an amount of 5.0 to 50.0% by weight, component ii) is provided in an amount of 40.0 to 90.0% by weight, component iii) is provided in an amount of 1.0 to 20.0% by weight, and component iv) is provided in an amount of 1.0 to 15.0% by weight, calculated on the sum of components i) to iv). |
US11254809B2 |
Polymer composition and a process for production of the polymer composition
A polymer composition comprising a base resin is disclosed herein. The base resin includes a very high molecular weight polyethylene component, a low molecular weight polyethylene component having a weight average molecular weight lower than a weight average molecular weight of the very high molecular weight component and a high molecular weight component having a weight average molecular weight higher than the weight average molecular weight of the low molecular weight component, but lower than the weight average molecular weight of the very high molecular weight component. The composition has a complex viscosity at 0.05 rad/s Eta0.05 rad/s of equal to or more than 800 kPa·s, a viscosity at a shear stress of 747 Pa (eta747) of equal to or less than 34000 kPas and a melt flow rate MFR5 of equal to or less than 0.17 g/10 min. |
US11254805B2 |
Eco-friendly flooring and method for manufacturing same
Described herein is flooring formed of an eco-friendly material, where the flooring has excellent heat resistance, durability, abrasion resistance and dimensional stability, and is formed of a non-PVC material and thus is recyclable via an extrusion processing at the time of disposal after use. Specifically, eco-friendly flooring is described in which a coating layer, an overlayer having ionomers, a printing layer, at least one middle layer, and at least one underlayer are laminated in order, where the overlayer of the flooring has ionomers, at least one of the middle layer and the underlayer has a thermoplastic polyolefin-based resin, a styrene-based resin, oil, and a filler, the thermoplastic polyolefin-based resin is contained in an amount of 50 to 150 parts by weight with respect to 100 parts by weight of the styrene-based resin, and the styrene-based resin may contain 25 to 45% styrene. |
US11254801B2 |
Modified polymerization initiator and modified conjugated diene- based polymer including functional group derived therefrom
The present invention relates to a modified polymerization initiator for a conjugated diene-based polymer, and a modified conjugated diene-based polymer including a functional group derived from the modified polymerization initiator. |
US11254800B2 |
Coating of inner plate part of vehicle
A coating of an outer plate contains a perylene-based pigment, and satisfies (ROH(P)/ROH(OA))≥74, where ROH(P) is the highlight reflectance of the coating of the outer plate at a peak wavelength at which reflectance reaches the maximum value in a spectral reflectance curve, and ROH(OA) is the average highlight reflectance of the coating of the outer plate in a complementary wavelength range. A coating of an inner plate part contains a perylene-based pigment and an iron oxide-based pigment, the content of the perylene-based pigment in the coating of the inner plate part is in units of PWC, and the mass ratio of the content of the iron oxide-based pigment to the content of the perylene-based pigment in the coating of the inner plate part is 3-20%. |
US11254799B2 |
Graphene composites
The present invention relates to novel nanocomposite materials, methods of making nanocomposites and uses of nanocomposite materials. In particular, the invention relates to composite materials which contain two-dimensional materials (e.g. graphene) in multi-layer form i.e. in a form which has a number of atomic layers. The properties of a composite material containing two-dimensional material is in multi-layer from are shown to be superior to those which contain the two-dimensional material in monolayer form. |
US11254798B2 |
One-pack type adhesive and fuel cell separator
Provided is a one-pack type adhesive which contains (A) an epoxy resin, (B) a curing agent, (C) a curing accelerator, (D) an inorganic filler and (E) a polycarbodiimide compound, and wherein: the curing agent (B) contains at least one amine-based curing agent; the curing accelerator (C) contains at least one capsule type curing accelerator; the inorganic filler (D) contains at least one flake-like inorganic filler; and the content of the inorganic filler (D) is 10-200 parts by mass relative to 100 parts by mass of the epoxy resin (A). |
US11254793B2 |
Catalyst-doped sizing agent for preparation of high areal weight fiber shelf-stable prepreg or molding compound intermediates
The present invention provides thermosetting resin pre-impregnated or infused fiber materials or prepregs comprising a thermosetting resin mixture and a fiber material component of a heat resistant fiber, such as carbon fiber, having an areal weight of from 500 to 3,000 g/m2 having a coating of from 0.5 to 4 phr of a latent, particulate curative or solid curative, preferably, dicyandiamide, wherein the prepregs are infused with a thermosetting resin mixture comprising (a) at least one liquid epoxy resin, and (b) a hardener and/or a catalyst, as well as methods of making the same. The prepregs of present invention enables the simple provision of lightweight composites having consistent resin cure throughout. |
US11254788B2 |
Mechanical ball-milling mthod for preparing a polydopamine-modified montmorillonite nanomaterial
A mechanical ball-milling method for preparing a polydopamine-modified montmorillonite nanomaterial is disclosed. The method includes dispersing a montmorillonite material in an aqueous solution, stirring, concentrating and collecting a concentrated montmorillonite solution for use; adding dopamine hydrochloride to a buffer solution to prepare a dopamine hydrochloride solution, with a concentration of 0.2-1 g/mL, and adjusting the pH value of the dopamine hydrochloride solution; and adding the dopamine hydrochloride solution and the concentrated montmorillonite solution simultaneously into a ball mill jar to form a mixture, and then subjecting the mixture to a ball milling for 0.3-6 hours, pouring the mixture out of the ball mill jar, and subjecting to a solid-liquid separation by a centrifugation, and then washing a solid product with deionized water for 3-6 times, and removing water from the solid product, to obtain the polydopamine-modified montmorillonite nanomaterial. |
US11254785B2 |
Process for preparing polyesters by using an additive
A process for reducing the amount of hydroxyl-end-groups of a polyester, wherein the polyester is prepared from at least one dicarboxylic acid and at least one dihydroxy alcohol, and at least one additive selected from the group consisting of carboxylic acid anhydride and mono-isocyanate, and wherein the additive is added during a step of prepolycondensation and/or during a step of polycondensation and/or after a step of polycondensation. |
US11254780B2 |
Method for preparing aqueous polyurethane dispersion
A method for preparing an aqueous polyurethane dispersion includes the following steps. The method characterized in that it introduces an ethoxy group to sodium ethylenediamine sulfonate (H2N—CH2CH2NHCH2CH2SO3Na) serving as an anionic chain extender to form sodium ethylenediamino ethoxyethyl sulfonate (H2NCH2CH2NHCH2CH2OCH2CH2SO3Na). Next, hydrophilic groups of sodium ethylenediamino ethoxyethyl sulfonate are used to prepare an aqueous polyurethane to improve the flowability of the resin, in which the polyurethane prepolymer has an isocyanate group at its end. More than one acrylate monomer is used for dilution and reduction of viscosity, and hydrophilic and amine groups containing sulfonate is used for water dispersion and to carry out a chain extension reaction. After that, an initiator is added for acrylic polymerization, so as to modify polyurethane with graft acrylic. |
US11254779B1 |
Reworkable ionomers
Some variations provide a reworkable ionomer composition comprising: a polymer containing a plurality of ionic monomers disposed in a chain backbone of the polymer, wherein the ionic monomers have a monomer charge polarity that is either positive or negative; and a plurality of ionic species disposed within the chain backbone of the polymer, wherein the ionic species have opposite charge polarity compared to the monomer charge polarity, wherein the ionic species and the ionic monomers are ionically bonded, and wherein the ionic species are capable of undergoing a reversible oxidation-state transition of at least +1 or −1 when in the presence of a redox reagent. The polymer may be selected from the group consisting of polyurethanes, polyacrylates, polyamides, polyesters, polyureas, polyurethane-ureas, polysiloxanes, polycarbonates, and combinations thereof. Many options for ionic monomers and ionic species are disclosed. These reworkable ionomers are useful for many commercial applications, including coatings and polymer parts. |
US11254769B1 |
Conducting polymer, 1-octadecene, polymer with 2,5 furandione, metal salts used as a barrier means
A Polymer used as a barrier means, having an acid number greater than 100. The Polymer has a valent metal ion which is bonded to at least one reactive group. The characteristics of the Polymer include, conductivities of 4 S/cm to 200 S/cm or more, depending upon the concentration and nature of the metal bound. The conductivity proportional to the amount of metal bound, the ability of the Polymer to bind metals having a +1, +2, +3, +4, or +5 valence charge to the Polymer, and the ability to bind two or more different metals to separate binding sites on the Polymer. |
US11254768B1 |
Conducting polymer, 1-octadecene, polymer with 2,5 furandione, metal salts used as an anti-infective means
A Polymer used as an anti-infective means, having an acid number greater than 100. The Polymer has a valent metal ion which is bonded to at least one reactive group. The characteristics of the Polymer include, conductivities of 4 S/cm to 200 S/cm or more, depending upon the concentration and nature of the metal bound. The conductivity proportional to the amount of metal bound, the ability of the Polymer to bind metals having a +1, +2, +3, +4, or +5 valence charge to the Polymer, and the ability to bind two or more different metals to separate binding sites on the Polymer. |
US11254766B2 |
Surfactant responsive emulsion polymerized micro-gels
A crosslinked, nonionic, amphiphilic polymer is prepared by polymerizing a monomer mixture comprising an amphiphilic additive. The obtained polymer is useful for forming a clearer yield stress fluid in combination with a surfactant. The yield stress fluid is capable of suspending insoluble materials in the presence of electrolytes, perfumes, fragrances and/or organic acid preservatives. |
US11254765B2 |
Polymers of haloalkyl and haloalkenyl ether (meth)acrylates
A curable composition containing at least one of a haloalkyl ether (meth)acrylate or a haloalkenyl ether (meth)acrylate and, optionally, one or more different types of co-monomers is cured to provide a polymer having advantageous properties as a result of the incorporation of halogenated functionality derived from the haloalkyl/haloalkenyl ether (meth)acrylate monomer. |
US11254764B2 |
Fluororpolymer compositions and coatings
A composition comprising at least one fluoropolymer and at least one solvent, wherein the solvent comprises a branched, partially fluorinated ether and wherein the partially fluorinated ether corresponds to the formula: CpF2p+1—O—CqH2q+1 wherein q is an integer from 1 to and 5 and p is an integer from 5 to 11; and wherein the fluoropolymer is a copolymer comprising at least 90% by weight (based on the total weight of the polymer, which is 100% by weight) of units derived from tetrafluoroethene (TFE) and one or more perfluorinated alkyl ethers selected from ethers corresponding to the general formula Rf—O—(CF2)n—CF═CF2 wherein n is 1 in which case the ether is an allyl ether, or 0 in which case the ether is a vinyl ether and Rf represents a perfluoroalkyl residue which may be interrupted once or more than once by an oxygen atom. Also provided are methods of preparing the compositions and methods for coating substrate with the compositions. |
US11254762B2 |
Multiple-component composition for producing a corrosion inhibiting hydrogel
A multiple-component composition that can be used for producing a corrosion inhibiting (meth)acrylic hydrogel. The multiple-component composition including at least one water soluble (meth)acrylic compound, at least one free radical initiator, at least one benzoate, and optionally at least one catalyst for free radical formation. A method for producing a hydrogel, to a hydrogel obtainable by the method, to a (meth)acrylic injection material, and to a method for sealing cracks, voids, flaws and cavities in building structures. |
US11254760B2 |
Method for producing purified fluoropolymer
Provided is a method for producing a purified fluoropolymer containing less fluoridable end groups. The production method includes: (a) melting a fluoropolymer to give a molten fluoropolymer; (b) reducing a reaction inhibitor in the molten fluoropolymer; (c) bringing the molten fluoropolymer into contact with an active substance after the step (b); and (d) removing a volatile matter from the molten fluoropolymer after the step (c). |
US11254758B2 |
Process for preparing a procatalyst for polymerization of olefins
The present invention relates to a process for preparing a procatalyst for polymerization of olefins, said process comprising contacting a magnesium-containing support with a halogen-containing titanium compound, an internal electron donor being a substituted 1,2-phenylene aromatic diester compound. |
US11254755B2 |
Modified conjugated diene-based polymer and rubber composition including the same
A modified conjugated diene-based polymer, and more particularly, a modified conjugated diene-based polymer having a unimodal molecular weight distribution curve measured by gel permeation chromatography (GPC), molecular weight distribution (PDI; MWD) of less than 1.7, and a Si content of 100 ppm or more based on weight, and including a repeating unit derived from an aromatic vinyl monomer in an amount of greater than 0 wt % and less than 15 wt %, and a rubber composition including the same. |
US11254754B2 |
Biocompatible polysaccharide hydrogels and methods of usage
The disclosure provides hydrogel compositions comprising polysaccharides with repeat units and methods of synthesis and usage. |
US11254751B2 |
EphA5-binding antibodies and uses thereof and selection of phage-displayed accessible recombinant targeted antibodies
Isolated or recombinant Eph A5 or GRP78 targeting antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. A method of rapidly identifying antibodies or antibody fragments for the treatment of cancer using a combination of in vitro and in vivo methodologies is also provided. |
US11254747B2 |
Covalent diabodies and uses thereof
The present invention is directed to diabody molecules and uses thereof in the treatment of a variety of diseases and disorders, including immunological disorders, infectious disease, intoxication and cancers. The diabody molecules of the invention comprise two polypeptide chains that associate to form at least two epitope binding sites, which may recognize the same or different epitopes on the same or differing antigens. Additionally, the antigens may be from the same or different molecules. The individual polypeptide chains of the diabody molecule may be covalently bound through nonpeptide bond covalent bonds, such as, but not limited to, disulfide bonding of cysteine residues located within each polypeptide chain. In particular embodiments, the diabody molecules of the present invention further comprise an Fc region, which allows antibody like functionality to engineered into the molecule. |
US11254745B1 |
Anti-CD4 antibodies
The present disclosure provides herein anti-CD4 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof. |
US11254743B2 |
Anti-CD33 antibodies and methods of use thereof
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof. |
US11254740B2 |
Methods of treatment using IL-23p19 monoclonal antibodies
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same. |
US11254736B2 |
Antibodies comprising a common light chain and uses thereof
Peptides and uses thereof, such as a common light chain in an antibody, are provided. |
US11254734B2 |
Fab molecules with a rodent hinge region and a non-rodent CH1 region
The disclosure relates to novel Fab molecules comprising a modified heavy chain constant region. The modified constant region prevents the recognition of the Fab molecules by anti-Fab antibodies present in a host's serum. The disclosure further relates to methods of generating such modified Fab molecules for biological, diagnostic, pharmaceutical and other uses. |
US11254730B2 |
N-terminal recombinant protein of CCR4 and use thereof
The present invention provides a recombinant protein or a derivative thereof, wherein the recombinant protein has an amino acid sequence of the N-terminal portion of CC chemokine receptor 4 (CCR4). The invention also provides the use of the recombinant protein or a derivative thereof for treating or preventing a disease or condition associated with CCR4 signaling, such as an allergic disease, inflammatory enteritis, psoriasis, an inflammatory skin disease, vasculitis, spondyloarthropathy, scleroderma, asthma, a respiratory allergic disease, an autoimmune disease, graft rejection, leukemia, lymphoma, a blood-borne cancer, a disease requiring inhibition of undesirable inflammation, and a cancer. |
US11254729B2 |
IL-7R-α binding compounds
IL-7Rα ligands and compounds comprising IL-7Rα ligands are disclosed. The IL-7Rα binding compounds include fusion proteins comprising the IL-7Rα ligands and can act as IL-7R agonists. |
US11254728B2 |
Method for producing monomeric and multimeric molecules and uses thereof
Herein is reported a method for the production of a polypeptide that is biologically active as n-mer comprising a nucleic acid encoding a fusion polypeptide according to the following formula (Bn-CSo-Is-CSp-FC-CSq-It-CSr-Bm)u, wherein B denotes a polypeptide that is biologically active as n-mer and forms non-defined aggregates/multimers upon expression in the absence of a fused Fc-region, FC denotes a heavy chain Fc-region polypeptide, CS denotes a cleavage site, and I denotes an intervening amino acid sequence, wherein FC does not substantially bind to an Fc-receptor, recovering the fusion polypeptide from the cell or the cultivation medium, optionally cleaving the fusion polypeptide with a protease, and thereby producing a polypeptide that is biologically active as n-mer and forms non-defined aggregates/multimers upon expression in the absence of a fused Fc-region. |
US11254725B2 |
Targeted therapeutic lysosomal enzyme fusion proteins and uses thereof
The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. |
US11254723B2 |
Recombinant human-basic fibroblast growth factor (rh-bFGF) and pharmaceutical composition comprising rh-bFGF
Provided are a mutated nucleic acid molecule of a recombinant human-basic fibroblast growth factor (rh-bFGF), a pharmaceutical composition of the rh-bFGF, and a use thereof. |
US11254720B2 |
Methods and systems for designing and/or characterizing soluble lipidated ligand agents
The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest. |
US11254719B2 |
Animal model of longevity and related methods for increasing longevity and inhibiting tumorigenesis
A genetically-modified non-human animal model of longevity and increased health span, which is associated with reduced tumorigenesis and tumor metastasis, as well as related methods for increasing longevity and health span, reducing tumorigenesis and tumor metastasis, and identifying active agents that confer increased longevity or health span, or reduced tumorigenesis or tumor metastasis. |
US11254716B2 |
Peptides for binding epidermal growth factor
A polypeptide having a sequence at least 60% identical to SEQ ID NO: 1 (WFEWPYWEMNVPDVWN) is provided. The polypeptide includes no more than 100 total amino acid residues. |
US11254715B2 |
Protein associated with disease resistance and encoding gene thereof, and use thereof in regulation of plant disease resistance
A protein provided is: a) a protein with an amino acid sequence as shown in amino acids 1-264 of SEQ ID NO: 1; b) a protein that is associated with disease resistance and obtained after an amino acid sequence as shown in amino acids 1-264 of SEQ ID NO: 1 in a Sequence Listing is subjected to substitution and/or deletion and/or addition of one or several amino acid residues; c) a protein with an amino acid sequence as shown in SEQ ID NO: 1; or d) a protein that is associated with disease resistance and obtained after the amino acid sequence as shown in SEQ ID NO: 1 in the Sequence Listing is subjected to substitution and/or deletion and/or addition of one or several amino acid residues. Experiments demonstrate that the protein associated with disease resistance and the encoding gene thereof can be used to enhance plant disease resistance. |
US11254713B2 |
Method to enhance immunogenicity of live typhoid vaccines and carriers
In certain embodiments, a recombinant attenuated derivative of a pathogenic Salmonella enterica serovar typhi cell is provided, (a) wherein one or more genes encoding subunits of a stg operon (Salmonella typhi Δstg) are inactivated or deleted resulting in a decrease of Stg adhesin/fimbriae production as compared to genes encoding a wild-type Stg operon (stgABCC′D), and/or (b) the cell comprises a nucleic acid encoding at least one of a gene encoding a subunit of a long polar fimbriae (Lpf) of S. enterica serovar Typhimurium protein. In certain embodiments, vaccines and compositions, and methods of use of the recombinant attenuated derivative of a pathogenic Salmonella enterica serovar typhi cell are provided. |
US11254709B2 |
Method for promoting Bacillus subtilis to synthesize surfactin based on multi-gene synergy
The present invention discloses a method for promoting B. subtilis to synthesize surfactin based on multi-gene synergy, and belongs to the field of genetic engineering. Firstly, B. subtilis is enabled to obtain the ability to synthesize surfactin by integrant expression of sfp protein derived from a high-yield strain, on this basis, by knocking out genes associated with a competitive pathway, overexpressing genes associated with the surfactin tolerance of B. subtilis, strengthening genes associated with a branched chain fatty acid synthesis pathway or improving the intracellular srfA gene transcription level, the synergy among genes is realized, and systemic metabolic engineering transformation is performed on the B. subtilis, thereby greatly improving the ability of B. subtilis genetically engineered bacteria to synthesize surfactin. Compared with a starting strain B. subtilis 168, the amount of extracellular accumulation of surfactin of the B. subtilis genetically engineered bacteria increases from 0 g/L to 12.8 g/L. The present invention obtains the recombinant B. subtilis with significantly improved ability to synthesize surfactin by multi-gene cooperative transformation of B. subtilis, and has a good application prospect. |
US11254706B2 |
Peptide and its derivatives capable of inhibiting replication of hepatitis V virus in human adipose-derived stem cells and hepatocytes
Hepatitis C virus (HCV) infection is a leading cause for liver cirrhosis and hepatocellular carcinoma worldwide2. Current therapeutic regimens are usually poorly tolerated and only effective in a proportion of infected individuals. We discovered a peptide with sequence of DEAQETAVSSHEQD (SEQ ID NO: 1), a fragment of rabbit α1-antiproteinase F, and its derivatives DEAQETAVSSHEQ (SEQ ID NO: 2) and QETAVSSHEQD (SEQ ID NO: 3), significantly inhibit serum-borne HCV replication in hADSC and human hepatocytes. |
US11254705B2 |
Cyclic peptide analogs and conjugates thereof
Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates. |
US11254704B2 |
Compounds and methods for reducing or inhibiting aggregation of proteins in a subject
Disclosed herein are compounds for the treatment of neurodegenerative diseases and compositions comprising the same. |
US11254702B2 |
Thionyl tetrafluoride modified compounds and uses
Thionyl tetrafluoride gas reacts efficiently with primary amines to form reactive iminosulfur oxydifluoride compounds. These dual SVI—F loaded iminosulfur oxydifluoride compounds, in turn, readily react with secondary amines or aryloxy silyl ethers (ArO—SiR3), yielding the corresponding fused heteroatom-linked substrates. Iminosulfur oxyfluoride polymers also are provided by disclosed methods. |
US11254697B2 |
Organic electroluminescent materials and devices
A compound including a first ligand LA having the structure of Formula I, is disclosed. In Formula I, rings A and B are each a 6-membered rings; Z1 and Z2 are each carbon or nitrogen; each RA and RB is independently hydrogen or a variety of substituents; any two substituents are optionally joined or fused into a ring; at least one RA or RB comprises an aromatic group substituted by a bridge structure, and this RA or RB joins with an adjacent substituent and fuses to ring A or B; the bridge structure comprises a backbone structure that forms a fused first ring; the backbone structure is saturated, comprises at least one heteroatom, and is optionally further substituted; and the ligand LA is coordinated to a metal M that can be coordinated to other ligands. |
US11254694B2 |
Polycyclic compound and organic electroluminescence device including the same
A polycyclic compound and an organic electroluminescence device including the same, the polycyclic compound being represented by Formula 1: |
US11254692B2 |
Method for producing trichlorosilylsulfide anion and its use in the preparation of organosulfur compounds
Preparation of sulfur fine chemicals from sulfur sources is described. |
US11254689B2 |
Compounds
The invention relates to compounds of Formula (I) and their use in therapy, for example in the treatment of mycobacterial infections or in the treatment of diseases caused by mycobacterium, such as tuberculosis. |
US11254688B2 |
Benzyl-, (pyridin-3-yl)methyl -or (pyridin-4-yl)-methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyl transferase (GOAT) inhibitors
The present invention relates to compounds of general formula (I), wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity. |
US11254681B2 |
Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy. |
US11254675B2 |
Process for preparation of grapiprant
The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof. |
US11254672B2 |
Dihydrobenzimidazolones for medical treatment
The present invention provides selected dihydrobenzimidazolones which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and alter the substrate specificity of the CRBN E3 ubiquitin ligase complex, resulting in breakdown of intrinsic downstream proteins. The disclosed compounds are useful for the treatment of cancer. |
US11254666B2 |
Compound as GLS1 inhibitor
A compound as a GLS1 inhibitor as represented by formula (I) or a pharmaceutically acceptable salt thereof. |
US11254664B2 |
Benzodiazepine derivatives as RSV inhibitors
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
US11254663B2 |
Substituted bicyclic compounds as farnesoid X receptor modulators
Disclosed are compounds of Formula (I): or a stereoisomer, a tautomer, or a salt or solvate thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. Also disclosed are pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions. |
US11254659B1 |
Capsaicinoid prodrug compounds and their use in treating medical conditions
The invention provides capsaicinoid prodrug compounds (e.g., prodrugs of resiniferatoxin, tinyatoxin, iodoresiniferatoxin, and related compounds), pharmaceutical compositions, and their use in the treatment of medical conditions, such as pain, and in agonizing TRPV1 activity. |
US11254657B2 |
Plinabulin compositions
Disclosed herein are plinabulin polymorphs, compositions, their use and preparation as therapeutic agents. In particular, some embodiments relate to plinabulin monohydrate in a crystalline form. |
US11254656B2 |
Muscarinic agonists
This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1 or a salt thereof, wherein q, r, s, Q, R1, R2′, R2″, R3 and R4 are as defined herein. |
US11254654B2 |
Heterochromatin gene repression inhibitors
The present disclosure relates to chemical compounds that inhibit HP1-mediated heterochromatin formation, pharmaceutical compositions containing such compounds, methods of identifying such compounds, and their use in the treatment of disorders related to heterochromatin formation such as, for example, a disorder of cellular proliferation (e.g., cancer). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
US11254653B2 |
NLRP3 inflammasome inhibitors
The present invention relates to novel pyridazin-3-yl phenol compounds of Formula (I): wherein R1, R2, R3, R4, R5 and Z are defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical compositions and medicaments containing them, and their use in the treatment of diseases and disorders mediated by NLRP3. |
US11254651B2 |
Histone methyltransferase inhibitors
The present disclosure provides certain compounds that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers and hemoglobinpathies such as beta-thalassemia and sickle cell disease. Also provided are pharmaceutical compositions containing such compounds as well as processes and intermediates for preparing such compounds. |
US11254649B2 |
Crystalline fumarate salt of (S)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone
This disclosure relates to the crystalline fumarate salt of (S)[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone. The disclosure also relates to pharmaceutical compositions comprising the crystalline fumarate salt of (S)[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone. The disclosure also relates to methods of treating cancers comprising administering to a patient in need thereof the crystalline fumarate salt of (S)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone. |
US11254646B2 |
Ultra-low molecular weight imide containing quaternary ammonium salts having short hydrocarbon tails
The present technology is related to imide containing quaternary ammonium salts having a hydrocarbyl substituent of number average molecular weight less 300, and additive packages having such quaternary ammonium salts and improved stability. |
US11254642B2 |
Method for preparing 2-chloro-5-trifluoromethylpyridine
The present invention provides a method for the preparing of 2-chloro-5-trifluoromethylpyridine, comprising two steps of chlorofluorination reaction and chlorination reaction, the chlorination catalyst used in the chlorination reaction was chosen from a fluoride, an oxide, a hydroxide, a carbonate, or a chloride of magnesium, calcium and barium and a supported palladium catalyst; or under the action of at least one catalyst chosen from ZSM-5, 5A, β and 13× molecular sieves, 3-trifluoromethylpyridine and chlorine gas phase have reaction to obtain 2-chloro-5-trifluoromethylpyridine. Or, under the action of a catalyst chosen from a fluoride, an oxide, a hydroxide, a carbonate, or a chloride of magnesium, calcium, and barium and a supported palladium catalyst, 3-trifluoromethylpyridine and chlorine gas phase have reaction to obtain 2-chloro-5-trifluoromethylpyridine. The present invention has the advantages of easily availability and low-cost of raw materials, safe operation, high yield, easy isolation and recovery of catalyst, environmental protection, fast reaction speed and continuous production on a large-scale, etc. |
US11254640B2 |
N-substituted indoles and other heterocycles for treating brain disorders
The present invention provides N-substituted indoles and other heterocycles and methods of using the compounds for treating brain disorders. |
US11254638B2 |
Nitrileoxide compound
A compound of the formula (III): wherein R21 is a hydrogen atom or an alkyl group; R22 is a hydrogen atom or an alkyl group; and R23 is a divalent organic group. |
US11254634B2 |
Method for producing at least one of unsaturated aldehyde and unsaturated carboxylic acid and catalyst for producing at least one of unsaturated aldehyde and unsaturated carboxylic acid
Provided is a method for producing at least one of an unsaturated aldehyde and an unsaturated carboxylic acid from an alkene by an oxidation reaction, in which a n-layered catalyst layer (n≥2) is provided in a gas flow direction in a reaction tube, two or more kinds of catalysts having different activities are used; and the catalysts are packed in such a manner that dT≤20° C. is satisfied, when a difference between a temperature PTn of an exothermic peak in a n-th layer as counted from a gas inlet and a minimum value mTn−1 of a temperature of a catalyst layer which appears between an exothermic peak in a (n-1)th layer and an exothermic peak in a n-th layer from the gas inlet is represented as dT (=PTn−mTn−1), and the change rate of dT is 2.5 or less at a reaction bath temperature within a range of ±6° C. of a reaction bath temperature at which the highest yield is obtained. |
US11254633B2 |
Cannabis thin layer decarboxylation
Dried and or decarboxylated cannabis containing a known composition of cannabinoids is blended with other dried or decarboxylated cannabis of a known composition of cannabinoids and or mixed with other extracts of, isolates of, cannabisor synthetic cannabinoids to achieve a prescribed amount of cannabinoids in the blend. Decarboxylated cannabis is preferentially produced using controlled thin layer decarboxylation. Precision decarboxylation is optionally used to produce a precise pair ratio of acidic to neutral cannabinoid, eg THCA to THC or CBDA to CBD. Further a prescribed or selected terpene profile is mixed and applied to the blend. Once mixed the plant material is suitable for ingestion without further treatment and is dosed appropriately. |
US11254625B2 |
Process for inhibiting oligomerization of C3- to C5-olefins
Oligomerization of C3- to C5-olefins using a catalyst is inhibited, wherein the oligomerization is carried out in at least one reaction stage including at least one reactor and at least one distillation column, and wherein the oligomer content in the feed stream to the at least one reactor of the at least one reaction stage is at least 1% by weight. |
US11254622B2 |
NPK-Si-humate fertilizer, method for production and use thereof
A combined organomineral NPK—Si-humate fertilizer having at least one particulate mineral NPK fertilizer is provided, which has at least one nutrient compound of nitrogen, phosphorous or potassium; and a particulate humic substance based silicon fertilizer, having chelates of monosilicic acid-humate compounds. The application also relates to a method of production of the combined organomineral NPK—Si-humate fertilizer. |
US11254619B2 |
Dry composition including effervescent agents, biostimulant, and plant nutrient
A method for fabricating a dry composition is disclosed including combining a solid carbonate or a solid bicarbonate compound, a solid acid yielding compound, a biostimulant, and a plant nutrient. The dry composition may be processed into a tablet, dry powder, meal, or pellets and produce effervescence when a liquid, such as water or a water-based liquid is mixed with the dry composition. |
US11254614B2 |
Lightweight conductive mortar material, preparation method therefor and method of using thereof
Disclosed are a lightweight conductive mortar material, a preparation method therefor and use thereof. The lightweight conductive mortar material includes the following components in parts by weight: 100 parts of cement, 25 parts to 60 parts of a conductive porous lightweight aggregate loaded with a modified agar gel, and 30 parts to 45 parts of water. |
US11254613B2 |
Pervious concrete having a super-absorbent polymer
A pervious concrete composition comprising a superabsorbent polymer in a proportion of 0.03 0.07 wt. % cement, preferably about 0.045 wt. % of cement, thereby enabling a water:cement ratio of 0.35 0.50. The superabsorbent polymer can be a cross-linked sodium polyacrylate-acrylamide/acrylic acid copolymer, and is introduced in powdered form to a concrete mix, wherein it is hydrated during the mixing process. The pervious concrete compositions herein can therefore be made with a desirable water:cement ratio and without the need for water-reducers or viscosity modifying additives. The invention further comprises methods of installing the pervious concrete compositions. |
US11254612B2 |
Method of preparing nano-thin film of cement hydration product
A method of preparing a cement hydration product nano-thin film, the method including: (1) preparing a cement hydration product; (2) preparing a water sacrificial layer film; (3) depositing the cement hydration product obtained in (1) on the surface of the water sacrificial layer film obtained in (2) to obtain a cement hydration product film; and (4) immersing the cement hydration product film in a saturated aqueous solution of calcium hydroxide to dissolve the water sacrificial layer film to obtain a nano-thin film of the cement hydration product. |
US11254610B2 |
Composition and method for simultaneous water softening and silica removal in boiler feed water
A slurry product is shown for treating water to both soften the water and to remove silica. The slurry is prepared by blending, in an aqueous medium, hydrated lime under the form of a slurry or of a powder with at least partly hydrated dolime, or magnesium hydroxide or magnesium oxide particles or a combination thereof under the form of a slurry or of a powder, to form an aqueous slurry where the amounts of the dolime, magnesium hydroxide or magnesium oxide particles or the combination thereof are provided such that the solid content of the slurry is up to 60% by weight of the slurry. The slurry also maintains a stable and pumpable viscosity for over a month. |
US11254603B2 |
Gradient tinted articles and methods of making the same
A glass-ceramic, includes a silicate-containing glass comprising a first portion and a second portion. A plurality of crystalline precipitates comprising at least one of W and Mo. The crystalline precipitates are distributed within at least one of the first and second portions of the silicate-containing glass. The glass-ceramic comprises a difference in absorbance between the first and second portions of 0.04 optical density (OD)/mm or greater over a wavelength range of from 400 nm to 1500 nm. |
US11254599B2 |
Method for producing rock wool and recoverable cast iron
The invention relates to a method for producing rock wool and cast iron by melting a mixture of materials such as basalt, blast-furnace slag, coke and components necessary for melting, with an admixture containing alumina, said admixture making it possible to adjust the alumina content in order to obtain a rock wool having the following composition (as wt %): Al2O3: 18-22; SiO2: 40-50; CaO: 10-15; MgO: <10; FeO: <2; Na2O: <4; K2O: <2. The method includes the following operations: producing by melting a slag and a cast iron, separating the slag and the cast iron, and performing a fibring operation on the slag followed by a bonding operation in order to obtain the rock wool. According to the invention, at least one spent adsorbent and/or catalyst is used as an admixture, said catalyst containing alumina in Al2O3 form. Said adsorbent and/or catalyst preferably contains at least one metal, and said metal is retrieved in the cast iron. |
US11254594B1 |
Floatable system and method for biologically treating wastewater using low density, high surface area substrates
A treatment system of the present invention generally includes a floating support structure having an upper flotation assembly, a base assembly that secures the bottom edges of a plurality of low density sheets, and vertical frame members that connect the upper flotation assembly to the base assembly. The sheets are generally vertically oriented although able to flex and sway independently. Substantially all regions of substantially all sheets are aerated. The sheets are constructed of an open weave substrate that allows the diffusion of gas, nutrients and food, while protecting and serving as an attachment site for a variety of microbial colonies in both anoxic and aerobic zones. In use a system of the present invention is inserted into a wastewater reservoir, and aerated, for treatment of the wastewater. |
US11254592B2 |
Processes and systems for treating sour water to remove sulfide compounds
A process for treating sour water includes combining the sour water with an alkali or alkaline metal hydroxide to produce a sour water mixture, the sour water comprising sulfides, passing an electric current through the sour water mixture, where passing the electric current through the sour water mixture causes at least a portion of the sulfides to react to produce a treated sour water comprising sulfates and having a pH of 7.1 to 9.8, saturating the at least a portion of the sulfates in an aqueous sulfate solution, and separating at least a portion of saturated sulfates from a saturated aqueous sulfate solution. |
US11254590B2 |
System and method for a hash table and data storage and access using the same
The present teaching relates to method, system, medium, and implementations for storage management. A hash table is constructed, having an index file having one or more slots, each of which includes one or more buckets. Each bucket stores one or more types of records, including a direct record, an indirect record, and a forwarding record. A direct record stores data directly in a bucket of a slot of the index file. When a storage request is received related to some relevant data, the request is handled based on the constructed hash table. |
US11254589B2 |
Systems and methods for separating surface materials from a fluid using acoustic pressure shock waves
A method of separating material, such as foam, sludge, oil or grease, at a fluid's surface, by applying acoustic pressure shock waves to the material and the fluid's surface such that acoustic pressure shock waves are propagated in liquid medium of the fluid and in gas medium above the fluid surface. |
US11254586B1 |
Selected serving and flavored sparkling beverage maker
A method for making a customized beverages in a beverage maker is provided using a filtered water system for processing pressurized potable water. The filter system is monitored to allow for certification of a filter system performance for a claimed contaminant reduction up through 320 gallons of use while providing NSF/ANSI Standard 42 or NSF/ANSI Standard 53 health claims when operated at a flow rate of at least 0.50 gallons per minute (gpm). |
US11254585B2 |
Method for treating pickling acid residue
A novel process for treating pickling acid residue and recovering sulfates and nickel therefrom has been developed. By lowering the pH of a magnesium compound slurry to 4-5.5 with sulfuric acid containing pickling acid residue in the presence of ammonium sulfate, both magnesium sulfate and nickel sulfate are solubilized. Magnesium sulfate and nickel sulfate solution is separated from the solids by filtration and an iron hydroxide and chromium hydroxide residue is obtained as a precipitate. Magnesium sulfate and nickel sulfate are then separated from the solution. |
US11254583B2 |
Titanium oxide powder, and dispersion and cosmetic using said powder
A titanium oxide powder of the present invention has a BET specific surface area of 5 m2/g or more and 15 m2/g or less and contains polyhedral-shaped titanium oxide particles having eight or more faces, in which a mass reduction rate in a case of being heated at 800° C. for 1 hour in an air atmosphere is 0.03% by mass or more and 0.5% by mass or less. |
US11254582B2 |
Processes for preparing lithium carbonate
There are provided methods for preparing lithium carbonate. For example, such methods can comprise reacting an aqueous composition comprising lithium hydroxide with CO2 by sparging the CO2 the said composition, thereby obtaining a precipitate comprising the lithium carbonate. The methods can also comprise inserting at least a portion of the precipitate into a clarifier and obtaining a supernatant comprising lithium bicarbonate and a solid comprising the lithium carbonate, separating the solid from the supernatant; and heating the supernatant at a desired temperature so as to at least partially convert the lithium bicarbonate into lithium carbonate. |
US11254581B2 |
Process to recover ammonium bicarbonate from wastewater
The present invention is a process, a method, and system for recovery and concentration of dissolved ammonium bicarbonate from a wastewater containing ammonia (NH3) using gas separation, condensation, and crystallization, each at controlled operating temperatures. The present invention includes 1) removal of ammonia from waste (sludges, semi-solids, and solids and liquids) without the use of chemicals at a temperature of at least 80 degrees Celsius, 2) condensing the gaseous containing ammonia, carbon dioxide and water vapor to remove water vapor concentrating the amount of gaseous ammonia and carbon dioxide, 3) concentrating the ammonia and carbon dioxide in the water by established means, such as concentrating the gas using partial condensation followed by passing the concentrated gas through an absorption column at a temperature of between about 20 and 50 degrees Celsius to form dissolved ammonium carbonate and ammonium bicarbonate, or total condensation followed by dewatering using reverse osmosis, and 4) crystallizing concentrated dissolved ammonium carbonate and ammonium bicarbonate at a temperature of less than about 35 degrees Celsius to form solid ammonium bicarbonate and ammonium carbonate. |
US11254580B2 |
Silica particle liquid dispersion and production method therefor
A method for producing a liquid dispersion containing irregular-shaped silica particles in which two or more primary particles are linked together, by simultaneously adding a liquid A containing silane alkoxide and a liquid B containing an alkali catalyst and water to a liquid I consisting substantially of an organic solvent to cause hydrolysis and polycondensation of the silane alkoxide, wherein the period from the start of the addition until the silica concentration of the reaction system at the end of the addition reaches 70% is 20% or less of the full reaction time period. |
US11254573B2 |
Lithium ion-conducting solid electrolyte and solid-state lithium ion rechargeable battery
A lithium ion-conducting solid electrolyte containing at least one metallic element selected from the group made of Zn, Ca, Mg, and Cu within a range of 0.01% by mass to 3.0% by mass, and a solid-state lithium ion rechargeable battery containing this lithium ion-conducting solid electrolyte. |
US11254570B2 |
Process for treating a mixed feed of hydrogen sulfide gas and ammonia gas to produce ammonium thiosulfate and including methodology for emissions control
This invention relates to production of an aqueous solution containing ammonium thiosulfate from a feed gas containing hydrogen sulfide (H2S) and ammonia (NH3). Sufficient separation of feed gas H2S from NH3 is achieved by controlling individual NH3 and H2S absorption mass-transfer rates in a single co-current stage, whereby a first gas contacts a first liquid containing ammonium bisulfite (ABS). Substantially more NH3 is absorbed than H2S, converting ABS to diammonium sulfite (DAS). A portion of DAS reacts with a sufficiently small portion of H2S to produce ATS and leaves as a second liquid stream. A larger portion of H2S leaves as a second gas stream. The second gas stream is oxidized to sulfur dioxide (SO2) comprising a third gas stream. The third gas stream contacts the second aqueous stream in a second contact stage whereby DAS in the second liquid stream is converted to ABS and returned to the first contacting zone. |
US11254569B2 |
Method and device for conversion of water into hydrogen peroxide
In a method and device for conversion of water into hydrogen peroxide (H2O2), a corona discharge zone is generated between a first electrode (10) and a second electrode (6) one of which is insulated and another of which is not insulated and wherein a respective surface of each of the electrodes face one another. The first electrode (10) is rotated so as to induce relative rotation between the first electrode and the second electrode; and liquid water is conveyed on to a surface of the first electrode facing the second electrode close to the axis of rotation (4) of the first electrode whereby the liquid water advances outward through the corona discharge zone towards a periphery of the first electrode under the action of centrifugal force caused by rotation of the first electrode. |
US11254568B2 |
Liquid fuel CPOX reformer and fuel cell systems, and methods of producing electricity
Integrated liquid fuel catalytic partial oxidation (CPOX) reformer and fuel cell systems can include a plurality or an array of spaced-apart CPOX reactor units, each reactor unit including an elongated tube having a gas-permeable wall with internal and external surfaces. The wall encloses an unobstructed gaseous flow passageway. At least a portion of the wall has CPOX catalyst disposed therein and/or comprising its structure. The catalyst-containing wall structure and open gaseous flow passageway enclosed thereby define a gaseous phase CPOX reaction zone, the catalyst-containing wall section being gas-permeable to allow gaseous CPOX reaction mixture to diffuse therein and hydrogen rich product reformate to diffuse therefrom. The liquid fuel CPOX reformer also can include a vaporizer, one or more igniters, and a source of liquid reformable fuel. The hydrogen-rich reformate can be converted to electricity within a fuel cell unit integrated with the CPOX reactor unit. |
US11254563B2 |
Mold material architecture for package device structures
Embodiments include a microelectronic device package structure having a die on a substrate, where a first side of the die is electrically coupled to the substrate, and a second side of the die is covered with a first material having a first thermal conductivity. A second material is adjacent to a sidewall of the die and adjacent to a sidewall of the first material. The second material has second thermal conductivity, smaller than the first thermal conductivity. The second material may have mechanical and/or underfill properties superior to those of the first material. Together, the two materials may provide a package structure having enhanced thermal and mechanical performance. |
US11254560B2 |
Transconductance amplifier
The present disclosure relates to an integrated circuit comprising a transconductance amplifier which is connectable to a microelectromechanical systems (MEMS) transducer. The transconductance amplifier comprises a first input coupled to a first current conveyor and a second input coupled to a second current conveyor for converting a single-ended or differential transducer signal voltage into an intermediate signal current representative of the transducer signal voltage through a shared reference resistor. The transconductance amplifier further comprises first and second output circuits coupled to the shared reference resistor and being configured to convert the intermediate current signal into a corresponding differential output current signal through first and second output terminals for driving a load. |
US11254556B2 |
Rope halter conversion attachment for bitless riding
A rope halter conversion attachment that attaches reins to a rope halter fitted to a horse's head to create a bitless bridle which allows a rider to communicate commands to the horse via the rope halter by manipulation of the reins. To accomplish this task, the rope halter conversion attachment forms an angle between the halter's cheek knot and the point of attachment of the reins. When rein tension is applied by the rider, this angle causes a pivoting motion at the halter's cheek knot that pulls on the nose band and creates pressure on the horse's nose. The pressure communicates nonverbal commands to the horse. |
US11254554B2 |
Dispensing nozzle assemblies
The present application provides a dispensing nozzle assembly for mixing a first fluid and a second fluid. The dispensing nozzle assembly may include a target assembly with a number of twisted fins and an injector ring assembly surrounding the target assembly in whole or in part. The injector ring assembly may include a number of first tubes with one or more threads therein directed towards the target assembly for the first fluid and a number of second tubes directed towards the target assembly for the second fluid such that the first fluid and the second fluid mix along the twisted fins of the target assembly. |
US11254553B2 |
Decapper and apparatus
A decapper for removing a cap from a laboratory sample container is presented. The decapper comprises a guidance. An apparatus comprising such a decapper is also presented. |
US11254552B2 |
Floor jack lift arm
A lift arm of a floor jack is composed of a number of components made from metal bar stock. The lift arm is adapted to transfer power and motion from a power unit to a saddle, which is adapted to be placed at a lift point of the vehicle, thereby applying pressure to the lift point and raising the vehicle. |
US11254551B2 |
Apparatus and method for placing and tensioning an aerial, rope through a traveler of a power line
An apparatus for controlling tension in a pulling rope that is attached to a flying, unmanned aerial device or drone may utilize a cylinder around which the rope is wound, a shaft that longitudinally passes through the cylinder, a disc brake rotor that is mounted to the shaft, a brake caliper that is mounted circumferentially at a periphery of the disc brake rotor, and a brake lever that tensions a cable that is attached to, and movable to control movement of, the brake caliper, which may be hydraulic, against surfaces the disc brake rotor. The brake lever may be hand actuated and mounted to a handlebar. A frame may be part of the apparatus and support apparatus components and may have a protruding hitch portion that inserts into a vehicle's receiver hitch. An adjustable pulling rope guide support through which the rope is threaded, mounts to the frame. |
US11254547B2 |
Work area monitoring system for lifting machines
A system includes a hoist drive mechanism that elevates and lowers a load hook from a boom and a detector that provides obstacle location and identification information. A processor receives the obstacle location and identification information from the detector and provides obstacle avoidance data in response thereto. |
US11254543B2 |
Elevator door panel
An elevator door panel including a front plate, a thermal insulation member, a fixing member, and a longitudinal reinforcement plate, wherein four bent parts are formed by bending upper and lower ends and both side ends of the front plate into a U shape toward the back surface, the longitudinal reinforcement plate is connected to the bent parts by two brim parts on the back surface of the front plate while forming a space between the back surface and the longitudinal reinforcement plate, and the thermal insulation member is provided in the space formed between the longitudinal reinforcement plate and the back surface and fixed by the fixing member. |
US11254538B2 |
Textile machine producing take-up packages and method of operating such a machine
A textile machine producing take-up packages, comprising a storage area for wound take-up packages, a detecting element for measuring the weight of each take-up package to be placed on the tray, a summing element for adding up the measured weights of the take-up packages to be placed on the storage area, and an output element for outputting an output signal if the sum of the measured weights of the take-up packages exceeds a predefined threshold value. |
US11254537B2 |
Printing apparatus and method of controlling printing apparatus
Provided is a printing apparatus comprising: a discharging unit configured to convey and discharge print media; a tray configured to receive print media discharged in a first direction from the discharging unit; and a drive unit configured to move the tray in a second direction perpendicular to the first direction. In discharging print media, the tray is moved in the second direction to thereby receive the discharged print media at a plurality of different positions on the tray. The tray is movable to a take-out position being a position closer in the second direction to a take-out side where print media are taken out than any of the positions at which the tray receives the print media discharged from the discharging unit. |
US11254536B2 |
Image forming apparatus
An image forming apparatus includes an image forming portion, a swingable member feeding portion, a sheet stacking portion including a stacking tray and a sheet feeding passage and movable between a first position where a sheet feed from the feeding portion is feedable to the sheet feeding passage and a second position away from the first position, and a movable member movable to a space, between the feeding portion and the stacking portion, generating with movement of the stacking portion from the first position to the second position in interrelation with the movement of the stacking portion from the first position to the second position. |
US11254532B2 |
Medium transport apparatus, image reading apparatus, and transport control method
A medium transport apparatus includes: a medium mounting section configured to mount a medium; a feed roller configured to feed the medium from the medium mounting section; a separation roller configured to nip and separate the medium from the feed roller; a plurality of sensors disposed at positions facing a surface of the medium and configured to detect movement of the medium; and a control unit configured to stop feeding of the medium based on detection values received from the sensors, wherein the plurality of sensors are disposed upstream of a nipping position by the feed roller and the separation roller with a gap in a width direction being a direction intersecting a medium feed direction and detect movement of the medium in the width direction. |
US11254527B2 |
Gangway having self-raising assembly
A gangway comprises a fixed platform and a support structure connected to the fixed platform in a manner that allows the support structure to rotate with respect to the fixed platform between a raised stowed position and a lowered deployed position. A self-raising assembly is operative to rotate the support structure from the deployed position to the stowed position. The self-raising assembly includes at least one fluid actuated cylinder connected between the fixed platform and a distal end of the support structure. A raising actuator is usable by an operator to cause operation of the cylinder in a manner that rotates the support structure toward the stowed position. |
US11254524B2 |
Debris carts and systems and methods of using same
Systems and methods for processing debris from job sites are disclosed. Carts for receiving the debris are also disclosed. Each cart has a base, a plurality of wheels extending downwardly from the base relative to a vertical axis, and a plurality of walls extending upwardly from the base. The walls and the base of each cart cooperate to define a debris-receiving space. The carts can be engaged by a lifting apparatus that rotates along an arcuate path to position the carts in an unloading position. |
US11254523B1 |
Slide mechanism for stacker
A system for eliminating the need to reposition a tracked/wheeled radial stacker during stacking operations is provided, the stacker having a linear conveyor having front and rear portions, the front and rear portions being displaceable between raised and lowered positions, a bogie having a pair of continuous tracks that are selectively elevated off the ground, a pair of wheels mounted to the bogie that are displaced upwardly and downwardly, the wheels defining axes that may be shifted to position the wheels in either a substantially radial or substantially longitudinal direction, and a hydraulic cylinder system mounted to the wheels for displacing the wheels upwardly to lower the tracks to the ground or downwardly to elevate the tracks off the ground. A pair of hydraulically driven, telescoping frame members may extend rearwardly from the bogie to a mounting system that mounts the frame members to the conveyor, the mounting system defining a longitudinally extending slot with a trolley slidably mounted to the slot, the telescoping frame members being mounted to the trolley at spaced mounting points so that by extending and retracting the frame members, the rear portion of the conveyor can be raised and lowered, thereby changing inclination of the conveyor, wherein the trolley moving longitudinally in the slot takes up longitudinal movement of the conveyor as the inclination of the conveyor is changed. |
US11254521B2 |
Mover for a transport apparatus
Mover for a transport apparatus in the beverage processing industry, the packaging industry, or the warehouse industry, where the mover can form a linear drive together with a guide rail and a long stator of the transport apparatus, and the mover comprises rolling mechanisms for moving along the guide rail, where the mover comprises a base body and one secondary part or two secondary parts, which, in the case of two secondary parts, are arranged on oppositely disposed sides of the base body and are suitable to interact with an electromagnetic field generated by the transport apparatus to drive the mover along the guide rail characterized in that the mover comprises a device for the continuously variable adjustment of the relative position of a secondary part relative to the base body. |
US11254519B1 |
Vehicle waste disposal system
A vehicle waste disposal system connected to a vehicle, the vehicle waste disposal system including a waste receiving container connected within a passenger compartment of the vehicle to receive at least one waste item therein, a waste storage container connected within a trunk of the vehicle to receive the at least one waste item from the waste receiving container and store the at least one waste item therein, a pipe connected at a first end to at least a portion of the waste receiving container and connected at a second end to at least a portion of the waste storage container, and an air dispensing unit connected to at least a portion of the waste receiving container and the pipe to move the at least one waste item from the waste receiving container to the waste storage container in response to extracting air from the waste receiving container and expelling the air into the pipe toward the waste storage container. |
US11254518B2 |
Automated unloading and loading robot system
A system includes a robot configured to load and/or unload from a location, such as a cargo carrier or building. The robot includes a base unit that has a transport system to move the base unit. A mast extends from the base unit, and the mast has a mast conveyor. An End of Arm Tool (EoAT) is coupled to the mast. The EoAT includes an EoAT conveyor configured to move a cargo item to and from the mast conveyor. A gripper mechanism is configured to move between a retracted position where the gripper mechanism is clear of the cargo item on the EoAT conveyor and an extended position where the gripper mechanism is able to grip the cargo item. |
US11254517B1 |
Liner and load assembly therefor
A load assembly includes a supply mechanism structured to supply a plurality of container closures, and a conveyance assembly comprising a star wheel including a number of load pockets structured to receive the container closures and move the container closures from the supply mechanism to a processing assembly. The star wheel has an outer perimeter. Each of the load pockets is structured to receive a corresponding one of the container closures inboard of the outer perimeter of the star wheel. |
US11254514B2 |
Feeding assembly, component handling assembly and method of feeding components
A feeding assembly and a method of feeding components comprising a track along which components can be moved, said track comprising a sloped surface and a ledge, wherein said sloped surface slopes in a direction perpendicular to the direction which the components move along the track so that the components maintain a tilted orientation as they move along the track, a pickup platform comprising a pocket which can receive components from said track, and a pivot on which the pickup platform can be selectively rotated between a first position and second position. In the first position, the pocket is aligned with the track and the pocket is parallel with the sloped surface of the track, so that a component can move from the track into the pocket of the pickup platform. In the second position the pocket is in a horizontal orientation. |
US11254510B2 |
Self-guiding and cargo-sensitive component platform and system for transferring components
A smart moving platform for transport of components in manufacturing includes a vehicle body, a transmission device, a conveying system, a detection device, a tag installation device, a control unit, and a tag reader. The conveying system conveys components. The detection device detects a location of the component and in a first predetermined area, the tag installation device installs and activates a tag on the component. The control unit writes component information to the activated tag and sets a predetermined period. The tag starts to count time elapsing, and the conveyor belt conveys the component to a second predetermined area. The tag reader reads the component information, the elapsed time, and a predetermined period of the tag. When the elapsed time matches the predetermined period, the conveying system sends the component to a third predetermined area. |
US11254502B2 |
Storage and retrieval system
An automated storage and retrieval system including at least one autonomous transport vehicle, a transfer deck that defines a transport surface for the vehicle, at least one reciprocating lift, a first and second pickface interface station connected to the deck and spaced apart from each other, each station forming a pickface transfer interfacing between the vehicle on the deck and the lift at each station so that a pickface is transferred between the lift and the vehicle at each station, wherein the vehicle is configured to pick a first pickface at the first station, traverse the deck and buffer the first pickface, or at least a portion thereof, at the second station so that the second station has multiple pickfaces buffered on a common support in an order sequence of pickfaces according to a predetermined case out order sequence of mixed case pickfaces. |
US11254501B2 |
Storage and retrieval system
A storage and retrieval system including a vertical array of storage levels, each storage level having storage locations, a multilevel vertical conveyor system configured to transport the uncontained case units to and from the vertical array of storage levels, each storage level being configured to receive uncontained case units from the multilevel vertical conveyor system, at least one autonomous transport confined to each storage level, the at least one autonomous transport being configured to transport the uncontained case units between respective storage locations and the multilevel vertical conveyor system, and a controller configured to effect operation of the multilevel vertical conveyor system and at least one autonomous transport for assembling orders of uncontained case units of different types without moving bundles of the same uncontained case unit type throughout the storage and retrieval system. |
US11254500B2 |
Refuse vehicle with electric reach apparatus
A refuse vehicle includes a chassis, tractive elements, a lift apparatus, and a reach assembly. The tractive elements couple with the chassis and support the refuse vehicle. The lift apparatus includes a track and a grabber assembly. The track includes a straight portion and a curved portion. The grabber assembly releasably grasps a refuse container and ascends or descends the track to lift and empty refuse into a body of the refuse vehicle. The reach assembly includes an outer member, a first extendable member, and a second extendable member. The first extendable member is received within an inner volume of the outer member and translates relative to the outer member. The second extendable member is received within an inner volume of the first extendable member and translates relative to the first extendable member. The lift apparatus is fixedly coupled at an outer end of the second extendable member. |
US11254490B2 |
All-in-one gift packaging system
A system for a greeting card. The greeting card has a planar greeting card portion and a greeting card cover moveably coupled to the planar greeting card portion. The greeting card cover can move from an open position whereby the planar greeting card portion is readable to a closed position adjacent to said planar greeting card portion whereby the planar greeting card portion is not readable. The greeting card portion is coupled to a gift storage compartment which has a volume and a depth for storing an item. The greeting card cover can open and close without moving the gift storage compartment. |
US11254488B2 |
Spray nozzle chip and a medicament delivery device comprising the same
A spray nozzle chip is presented having: a first layer provided with a first layer orifice, a mechanically flexible nozzle layer provided with a nozzle orifice, the spray nozzle chip having a valve functionality obtained by movement of the nozzle layer relative to the first layer due to pressure changes, wherein the nozzle orifice is closed when the nozzle layer is in a default non-pressurised state and wherein the nozzle orifice is opened and set in fluid communication with the first layer orifice when the nozzle layer is deformed due to pressure during a spraying operation, and wherein the spray nozzle chip further has a sealing layer configured to rupture when the nozzle layer is deformed due to applied pressure during a spraying operation. |
US11254486B2 |
Apparatus for dispensing objects and method
An apparatus for dispensing small objects is disclosed. The apparatus includes a frame forming an upper chamber and a lower chamber. The frame supports a rotatable barrel that is disposed between the chambers. The barrel is constructed from a folded rectangular sheet that forms a chamber with an opening. The rotatable barrel is oriented with the opening facing upward to receive objects from the upper chamber into the barrel's chamber, such that when the handle is rotated about a horizontal axis the barrel turns to orient the opening downward and deposit objects in the barrel's chamber into the lower chamber. |
US11254484B2 |
Evacuated bottle system
An evacuated bottle system including a bottle defining a hollow interior, the bottle having a neck defining an opening that provides fluid communication with the interior; a cap assembly including a funnel having a first portion and a second portion, where the second portion extends radially outward from the first portion to form a floor on an interior thereof and a shoulder on an exterior thereof, the first portion defining a first bore and the second portion defining a second bore fluidly connected to the first bore; a self serum stopper having a self sealing membrane that extends radially outward to overlie at least a portion of the floor of the funnel; and a cap having a cap wall sized to fit over the funnel and a cover portion extending radially inward from the cap wall. |
US11254479B2 |
Lid for a storage container
There is provided herein a lid for a vacuum storage container, which contains a lid body having a top side and an opposing bottom side, the lid comprising a pressure-release valve having a vacuum-sealed position and a vacuum-release position, and a collar on the bottom side of the lid body having an open end, the pressure-release valve extending from the top side of the lid body into the collar on the bottom side, and a sheath covering the open end of the collar on the bottom side, which sheath reduces a vacuum loss when the pressure-release valve is in the vacuum-sealed position while permitting a release of vacuum when the pressure-release valve is in the vacuum-release position. |
US11254478B2 |
Sanitary cover
A sanitary cover for various items is provided. The device includes a flexible member having a base opposite an end, an upper wall, a lower wall, and a pair of sidewalls defining an interior volume. In some embodiments, the end is open, wherein alternate embodiments an opening is defined through the lower wall. A closure is disposed along the opening, wherein the closure seals the interior volume when the closure is removably secured together. A germicidal coating is disposed on an exterior surface of the flexible member. |
US11254477B2 |
Extraction pressure vessel, method of manufacture, method of use
Devices and methods to extract a desired product from organic matter using supercritical fluid extraction processes are described herein. The extraction vessel generally includes a reaction chamber, a water jacket affixed to the reaction chamber capable of separate pressurization, and a closure mechanism with a gasket, a plug, and a cap ring with ACME threading. The extraction vessel may be sealed by hand closure without a need for additional tools to create a seal able to withstand pressures up to 5,000 psi. |
US11254475B2 |
Structure of mouth plug portion, and package
A structure of a mouth plug portion includes a nozzle and a cap, the nozzle includes a first outer protrusion and a second outer protrusion, the first outer protrusion includes a locking surface that locks the cap and a first guide surface spirally extending, the cap includes a cap body and a tamper band provided with a weak portion that can be broken by an external force received from the second outer protrusion during rotation of the cap body, the cap body includes a first inner protrusion and a second inner protrusion, an outer peripheral surface of the nozzle is provided with a second guide surface along which the first inner protrusion and the second inner protrusion can move in an axial direction. |
US11254472B2 |
Smart capsules
The technology relates to a cap 1 having a head 4 and a skirt 7 with a circumferential opening area 20 characterized in that the cap 1 may include a transponder 10 including and antenna circuit 14 and a leg circuit 17 the leg circuit 17 extending to the skirt 7 and being non-releasably affixed to the opening area 20, whereby the leg circuit 17 is breakable by disruption of the opening area 20. The transponder 10 stores and is able to transmit information on the integrity of the cap 1 to a reading device. |
US11254471B2 |
Tamper-evident, tear-open resealable package
A tamper-evident package utilizes a transparent resealable adhesive structure such as a tape or a label to cover the closure opening. Upon a first opening of the package frangible portions of the package front between adjacent arcuate cuts and slits defining the opening are torn. This tearing distorts the packaging film so that re-registration of the opposing lateral edges upon reclosing is not possible. This results in a package which is visually tamper-evident. The tamper-evident condition can be enhanced by graphics or other printing on the front of the package in the area of the closure to make the misalignment of a resealed closure viewed through the transparent structure more visually apparent. In one embodiment of the invention a series of arcuate cuts are centered laterally and are flanked on the right and left sides by two continuous wavy slits which form a portion of the closure opening. |
US11254468B1 |
Pallet system for railings
A pallet system for shipping and storage of railing segments. The pallet system captures the corners of a plurality of railing segments, thereby diminishing the weight, footprint, and materials of construction requirements. In some embodiments, a plurality of the pallet systems can be stacked. The diminished size of the pallet system components after removal of the railing segments can be returned to the shipper in a refund exchange arrangement. In some embodiments, the plurality of railing segments is maintained in a fixed relationship using a spacer that is inserted laterally through the plurality of railing segments. |
US11254467B2 |
A-Z EZ caddy
A foldable fabric lawn and indoor/outdoor caddy that opens with a flexible spring wire loaded frame when placed on the ground. Debris/material can be swept/raked into the invention via its flexible 27″ rubber sweeping edge or by other means (shovel, hands, drop-cloth). The invention can then be closed together with its two handles and locked together for transport by the user. A rear fabric handle aides in the dumping/disposal of the aforementioned debris. The invention can then be placed on the ground ready for its next use. The invention can be used for clean-up, yard/garden work, as a drop-cloth, gather trash, and construction debris. |
US11254463B1 |
Non-round plastic container with structural features
A non-round plastic container includes an upper portion, a sidewall portion, and a base portion. The upper portion includes an opening and the sidewall portion extends downwardly from the upper portion, and the base portion extends downwardly from the sidewall portion. In embodiments, the sidewall portion includes a front surface, a rear surface, and opposing side surfaces disposed between the front surface and the rear surface, and the front surface, rear surface, and opposing side surfaces each include a flat configured to contact a flat on an opposing surface associated with a similar container. In embodiments, the opposing sides may have a substantially straight or a curved/tapered configurations, and/or one or more surface of the container may include one or more reinforcing formations. In embodiments, the container has a substantially oval or ovaloid shape. |
US11254461B1 |
High speed label applicator systems and methods
A label application system for applying paper non-pressure adhesive labels to relatively short, round, straight-walled articles is constructed and designed so that labels to be applied to passing articles are delivered to the label application zone on a vacuum conveyor in a short feed orientation, with each label being oriented lengthwise across a width of the vacuum conveyor. At the time of labeling, the label is held stationary on a flat vacuum surface, and the label is applied by spinning the articles past the vacuum surface. As a result, the system is capable of labeling articles at processing speeds of up to or exceeding 800 articles per minute. |
US11254460B2 |
Cut and seal method and apparatus
The present disclosure provides an apparatus for forming a stream of individual packets, comprising a folder arranged to form a tubular web structure, a feeder arranged to feed the formed tubular web structure to a nip; a first rotor comprising a first sealing jaw and a knife, a second rotor comprising a second sealing jaw and an anvil, the sealing jaws, the knife and anvil rotating into opposing relation at the nip so as to form a severed, completed packet beyond the nip. The apparatus includes an open ended packet catcher adjacent the first and second rotors, which is arranged to catch the severed, completed packets beyond the nip whereby a stream of packets is established. The packet catcher includes a stripper disposed in a proximal location to at least one of the anvil, the knife and the sealing jaws when the anvil, the knife and/or the sealing jaws are rotated beyond the nip, whereby, should a completed packet stick to any of the anvil, the knife and/or the sealing jaws, the stripper is operative to free the stuck packet from the anvil, the knife and/or the sealing jaw. The present disclosure provides a fin sealer and method to seal a radially outwardly directed fin of a tubular web structure by directing the fin through a nip between a first and a second fin sealing rollers while communicating heat to the fin through at least one of the fin sealing rollers, the fin sealer being further arranged to maintain a nominal face-to-face relation between an outer annulus of the first fin sealing roller and an outer annulus of the second fin sealing roller with a flexible connection between a hub element of the second fin sealing roller with the outer annulus of the second fin sealing roller. A cooling system is also provided, which is operative upon one of the rotors of a cut and seal station. |
US11254458B2 |
Packaging machine with heated grid
A packaging machine for packaging products under vacuum, the packaging machine comprising a lid and a chamber bottom which together form a chamber, the chamber bottom having formed therein a suction opening which can be closed in a gas-tight manner and to which a suction device for evacuating the chamber is connected. An electrically heatable grid is arranged on the suction opening to prevent ice forming near or around the suction opening during evacuation of the chamber. |
US11254456B2 |
Component mounting system and tape scraps collecting device
There is provided a component mounting system including: a component mounting device group in which a plurality of component mounting devices that mount components supplied to a board transported in from an upstream side by a tape feeder and transport out the board to a downstream side, and cut a carrier tape after supplying the components by a cutter device and discharge scraps of carrier tape, are installed on a floor surface while being arranged in a direction of conveying the board; a main conveyor that is installed along an arrangement direction of the plurality of component mounting devices in a region on the floor surface under the component mounting device group, and transports the scraps of carrier tape discharged from each of the plurality of component mounting devices; and a scraps storage that is installed outside the region and stores the scraps of carrier tape transported by the main conveyor. |
US11254455B2 |
Packaging apparatus and method for wrapping absorbent paper product
Aspects of the present disclosure relate to packaging apparatuses and methods adapted to wrap absorbent paper product in a continuous sheet of film formed into tube shape with an asymmetric opening. A former may include a plurality of forming members, wherein each forming member includes an outer surface connected with an inner surface along an edge. In operation, a continuous sheet of film advances around the edges of the forming members and forms an opening. In addition, opposing longitudinal edges of the continuous sheet are guided into an overlapping arrangement that forms the plastic film into a tube shape that extends downstream from the opening in the machine direction. The opening is symmetrical about a first axis and is asymmetrical about a second axis. Absorbent paper product to be packaged advances in the machine direction through the opening and into the tube. |
US11254453B2 |
Smallsat payload configuration
Techniques for deploying a plurality of smallsats from a common launch vehicle are disclosed where a structural arrangement provides a load path between an upper stage of the launch and the plurality of spacecraft. Each spacecraft is mechanically coupled with the launch vehicle upper stage only by the structural arrangement. The structural arrangement includes at least one trunk member that is approximately aligned with the longitudinal axis of the launch vehicle upper stage, a plurality of branch members, each branch member being attached to the trunk member and having at least a first end portion that is substantially outboard from the longitudinal axis; and a plurality of mechanical linkages, each linkage coupled at a first end with a first respective spacecraft and coupled at a second end with one of the plurality of branch members, the trunk member or a second respective spacecraft. |
US11254452B2 |
Flexible radiative fin for a spacecraft
A radiative fin for a spacecraft is disclosed having an end fitting of heat conductive material, configured to be mounted on the spacecraft, a flexible radiative laminate, connected to the end fitting at one end and having an opposite free end, at least one pyrolytic graphite sheet, and at least one heat emission layer in contact with the pyrolythic graphite sheet on at least part of the surface of the pyrolythic graphite sheet, and a flexible rod, extending from the end fitting along at least part of a side of the flexible radiative laminate and being affixed to the latter. The flexible rod is adapted to occupy a folded position and a deployed position and to exert, while in the folded position, a deployment torque adapted to bring the flexible rod back to the deployed position. |
US11254451B2 |
Pre-deployment battery power conservation for spacecraft
Embodiments of the present disclosure are directed to techniques for autonomously transitioning a spacecraft from a power-saving state to a power-consuming state at a time after launch of the spacecraft on a launch vehicle. Because the spacecraft can autonomously detect conditions for transitioning to the power-consuming state, commands received via an umbilical connection to the launch vehicle, or detecting the presence or absence of such a connection, is unnecessary, thereby removing several technical barriers to eliminating such umbilical connections altogether. In some embodiments, low-cost vacuum detection devices that use very small amounts of power may be used by the spacecraft to detect when the spacecraft has reached an altitude suitable for transitioning to the power-consuming state. |
US11254444B2 |
Gimbal, photographing apparatus having same, and unmanned aerial vehicle
An embodiment of the present invention provides a gimbal, a photographing apparatus having same, and an unmanned aerial vehicle. The gimbal includes at least two drive assemblies connected successively; a carrying housing configured to mount the photographing apparatus; one drive assembly of the at least two drive assemblies being mounted within the carrying housing, and the at least two drive assemblies being capable of driving the carrying housing to rotate toward at least two directions, so as to adjust an angle of the photographing apparatus from the at least two directions. |
US11254442B2 |
Logic control for autonomously and manually locking overhead bins for enhanced safety
A control system and method of controlling access to storage bins in a vehicle. The system includes a lock configured to be selectively movable between a locked position to prevent access to an interior of the storage bins and an unlocked position to allow access to the interior of the storage bins. A switch is positioned in a cabin of the vehicle. A control circuit is configured to determine an operational status of the vehicle and selectively position the locks. The control circuit can also receive an override signal from the switch and unlock the locks in certain situations. |
US11254439B2 |
Catalytic fuel tank inerting apparatus for aircraft
Fuel tank inerting systems for aircraft are provided. The systems include a fuel tank, a catalytic reactor arranged to receive a first reactant from a first reactant source and a second reactant from a second reactant source to generate an inert gas that is supplied to the fuel tank to fill an ullage space of the fuel tank, a heat exchanger arranged between the catalytic reactor and the fuel tank and configured to at least one of cool and condense an output from the catalytic reactor to separate out the inert gas, and a controller configured to perform a light-off operation of the catalytic reactor by controlling at least one light-off parameter and, after light-off occurs, adjusting the at least one light-off parameter to an operating level, wherein the at least one light-off parameter comprises a temperature of the catalytic reactor. |
US11254438B2 |
Vessel for enclosing at least one sensor within a fuel tank
A vessel designed for enclosing at least one sensor is arranged within a fuel tank. The vessel is provided with a fuel inlet connected to a refuelling arrangement of the tank, and with through-holes for the fuel to exit the vessel to the tank or to enter the vessel from the tank. It allows that measurement results which are provided by the sensor during a refuelling operation relate to the fuel currently admitted into the tank, separately from the fuel initially contained in the tank before the refuelling operation has started. |
US11254435B2 |
Supplemental pack driven by bleed air and cabin air
An airplane is provided. The airplane includes a pack. The pack includes a shaft, a compressor, and a turbine coupled to the compressor via the shaft. The turbine receives and expands a first medium to provide power to the compressor via the shaft. The compressor receives and compresses a second medium in accordance with the power provided by the turbine via the shaft. The turbine is fluidly coupled to a heat exchanger of an air conditioning system. |
US11254432B2 |
Storage compartment for the overhead region of a passenger cabin
A storage compartment for the overhead region of a passenger cabin of a passenger aircraft has a carrier which can be mounted in the passenger aircraft, and a pivoting part for receiving a storage item. The pivoting part is mounted on the carrier so as to be pivotable about a pivot axis in a pivoting region between an open position and a closing position. The storage compartment further contains a closing force module. The closing force module contains a switching module by which the closing force module can be brought into an active state or into a passive state. In the active state, a greater closing moment is brought about in the direction of the closing position on the pivoting part by the closing force module, at least in a partial region of the pivoting region, than in the passive state. The closing force module is configured free from electricity with respect to the generation of the closing moment and/or with respect to the switching over between the active state and passive state. |
US11254431B2 |
Airstair system with deployable upper step
Airstair systems and associated methods are disclosed. In one embodiment, the airstair comprises a deployable upper step, a primary deployment device and a secondary deployment device. The upper step is movable between a stowed configuration when a door of the aircraft is closed and a deployed configuration when the door is open. The primary deployment device resiliently biases the upper step toward the deployed configuration. The secondary deployment device is movable in coordination with a movement of the door and configured to drive the deployable upper step toward the deployed configuration during opening of the door and during a failure of the primary deployment device. |
US11254428B2 |
Method for controlling unmanned aircraft, server, and remote control device
A method for controlling an unmanned aerial vehicle (“UAV”) includes receiving locking instruction information from a user terminal for locking the UAV. The method also includes transmitting a locking command to a remote control device of the UAV based on the locking instruction information, to instruct the remote control device to lock the UAV based on the locking command. |
US11254427B2 |
Unmanned aerial vehicle having camera, and method for unmanned aerial vehicle to process image
An unmanned aerial vehicle has a main body, a plurality of propeller connection parts extending from at least one side surface of the main body by a specific length, a plurality of propellers respectively connected to ends of the plurality of propeller connection parts, and a plurality of cameras mounted on at least one surface of the main body. A first camera interposed between the plurality of propeller connection parts among the plurality of cameras is disposed spaced from a center point of the main body by a distance of a first size. A first virtual straight line connecting a center point of a first propeller disposed adjacent to the first camera among the plurality of propellers to a center point of the main body has a length of a second size. |
US11254426B2 |
Wing unit, wing flapping apparatus, and method of manufacturing wing unit
A wing unit is used in a wing flapping apparatus to perform a swinging motion to thereby generate levitation force. The wing unit includes a nonwoven fabric that forms a wing surface; a frame body overlaid on the nonwoven fabric and extending along the wing surface; and a resin material disposed in a cavity included in the nonwoven fabric to integrate the nonwoven fabric and the frame body with each other. According to this configuration, a light-weight and high-strength wing unit that produces a suppressed wing flapping noise, a wing flapping apparatus including the wing unit, and a method of manufacturing the wing unit are provided. |
US11254425B2 |
Differential blade geometry for rotor assemblies
Rotor assemblies for aircraft are described that include a plurality of blades that are disposed vertically on a common axis along different horizontal planes. When the rotor assemblies are free-wheeling, the blades form a vertically stacked configuration, and when the rotor assembly is driven in rotation to generate lift, the blades bloom out from the vertically stacked configuration. At least one of the blades in the rotor assembly has a blade geometry that is different with respect to other blades such that when the blades are vertically stacked and free-wheeling, the collective shape of the blades is aerodynamic in shape, based on the different blade geometry, that reduces aerodynamic drag on the rotor assembly. |
US11254424B2 |
Balance weight assemblies for rotor blades
A balance weight assembly for a rotor blade of a rotorcraft. The balance weight assembly includes a balance weight pocket formed by a balance weight tray and a cover. The balance weight tray has an upper surface including a lip region extending outwardly from a projected region with an outboard boss. A balance weight receiving cavity is recessed from the upper surface and contains a plurality of balance weights. The projected region is disposed within an opening in a hollow blade spar such that the outboard boss of the balance weight tray has a contact relationship with an outboard surface of the opening. The cover is coupled to the balance weight tray such that the lip region of the balance weight tray and at least a portion of the cover have a clamping relationship with the blade spar, thereby coupling the balance weight pocket to the blade spar. |
US11254422B2 |
System and method for reducing aircraft brake wear
A system and method are provided for continuous monitoring and controlling of aircraft braking that can reduce brake wear and aircraft operating costs through the retention of carbon brake powder from the brakes or addition of carbon powder in a device mounted with respect to the brake disc stack. The use of carbon powder reduces brake wear by providing small particles between the brake discs, acting as a buffer between the brake discs when the brake stack is clamped together. Moreover, when carbon powder or small particles are used at application, such use reduces the roughness of the carbon surface and reduces the number of large particles from braking off the carbon surface, thereby reducing brake wear. Adaptive or selective braking may be used in conjunction with carbon powder to further reduce carbon brake wear. |
US11254419B2 |
Bistable pitch propeller system with bidirectional propeller rotation
A propeller includes a blade free to rotate. A first stop is positioned to mechanically engage one or both of a first portion of the blade and a first structure coupled to the blade when the blade is in a first position at a first end of the rotational range of motion. A second stop is positioned to mechanically engage one or both of a second portion of the blade and a second structure coupled to the blade when the blade is in a second position at a second end of the defined rotational range. The blade rotates to the first position against the first stop when the propeller is rotated in a first direction and to the second position against the second stop when the propeller is rotated in a second direction. |
US11254411B2 |
Airfoil-shaped body with a variable outer shape
An airfoil-shaped body having a variable outer shape, comprising: a first skin, defining a suction surface, a second skin, defining a pressure surface and connected to the first skin at least at a leading edge and/or a trailing edge of the airfoil-shaped body, at least one elongate stiffening beam, arranged inside a cavity of the airfoil-shaped body and secured to at least one of said first and second skins, the stiffening beam including at least a first and a second beam section arranged one after the other and a joining member, arranged between end portions of the beam sections and connected thereto, said joining member being adapted to allow relative movement between the beam sections by an elastic deformation; and an actuator that is operationally associated with said elongate stiffening beam, wherein, upon operating the actuator, the first beam section is moved with respect to the second beam section, or vice versa, changing the orientation of the beam sections with respect to each other, which causes a change in the variable outer shape of the airfoil-shaped body. |
US11254407B2 |
Watercraft
A controller receives a signal indicating an operating amount and an operating direction of a steering member. When the operating amount of the steering member is greater than or equal to a steering threshold, the controller causes right and left propulsion devices to generate thrusts oriented in opposite directions in a back-and-forth direction such that a vessel body is turned in a corresponding direction to the operating direction of the steering member. |
US11254403B2 |
Salvage suit for shipwrecks with high functionality and insulation
This suit (1) includes an access opening (30) to the inner cavity or receptacle (10) and a facial opening (50) that are independent; around the facial opening (50), the structure of insulation walls (2) includes a hood (5) and both openings (30, 50), access (30) and facial (50), surrounded by a unfoldable sleeve (4) that is projected from the structure of insulation walls (2); the outer cover of protection includes a headpiece cover (7) that covers the hood (5) and a body cover (6) that are separated by a surrounding passage (9) through which the unfoldable sleeve (4) is capable of unfolding, until forming an environmental protection over said hood (5) and over said access opening (30). |
US11254402B1 |
Method and system for automated launch control of a marine vessel
A method of controlling propulsion for automated launch control includes receiving a user-selected command associated with wake surfing, accessing a predetermined RPM limit associated with the user-selected command, and automatically increasing rotational speed of a powerhead to accelerate the marine vessel to a vessel speed setpoint such that the rotational speed does not exceed the predetermined RPM limit. Once the marine vessel is traveling at the vessel speed setpoint, a cruising RPM value associated with the vessel speed setpoint is identified. A difference between the predetermined RPM limit and the cruising RPM value is determined, and then the predetermined RPM limit is adjusted to an adapted RPM limit based on the difference. The adapted RPM limit is then stored for use during a subsequent launch. |
US11254399B2 |
Floating platform for maritime surveillance
An unmanned, autonomous, self-sustaining and self-repairable floating platform which is positioned at a fixed location within the sea, capable of constantly monitoring, without having to be removed, a specific maritime zone including a sea surface area and the aerial and underwater space pertaining to this sea surface area, the platform comprising telecommunication means adapted to exchange surveillance related information with a Command, Communication and Control center. The platform comprises a deck maintained well above sea surface through a connecting member with an underlying, fully or partially submerged, system of floaters and is equipped with a variety of sensors and surveillance systems such as radar, Li-dar, sonar, electromagnetic, unmanned vehicles (UAVs, UUVs and USVs), active and passive self-protection systems as well as research and rescue equipment. A mast having a substantial height (usually 40-50 m) and equipped with appropriate surveillance devices is mounted and ex-tends vertically upwardly the deck. |
US11254392B2 |
Mooring apparatus
A mooring apparatus (10a; 10b; 10c; 10d) comprising a socket (15a; 15b; 15c; 15d), a connection member (20a; 20b; 20c; 20d), and an arrangement (25a; 25b; 25c; 25d) for positioning and/or controlling the disposition of the connection member (20a; 20b; 20c; 20d) relative to the socket (15a; 15b; 15c; 15d), the connection member (20a; 20b; 20c; 20d) being receivable and/or retainable in the socket (15a; 15b; 15c; 15d). A method of configuring a mooring apparatus (10a; 10b; 10c; 10d), wherein the method comprises providing the mooring apparatus (10a; 10b; 10c; 10d), the method further comprising connecting a first portion of a line (35) to a line engaging apparatus (30a) and positioning or extending the line (35) around the positioning arrangement (25a; 25b; 25c; 25d). |
US11254386B2 |
Electric bicycle having a communication system
An electric bicycle that has a communication system, including at least one electronic processing module for processing information for the rider of the electric bicycle, and at least one signal device for providing the processed information to the rider. To reduce safety risks due to the rider being distracted by his/her surroundings while riding the electric bicycle and to increase riding comfort, the at least one signal device is designed to output the information as a tactile, optical, and/or acoustic signal emitted by the electric bicycle in order to spontaneously influence the rider. |
US11254385B2 |
Headlight device
A headlight device includes a first light source for high beam, a second light source for low beam and a third light source for low beam. In the headlight device, the second light source and the third light source are disposed on opposite sides of the first light source so as to sandwich the first light source therebetween. Thus, it is possible to provide a headlight device for which the entirety can be made to appear bright. |
US11254384B2 |
Vehicle lamp
This vehicular lighting equipment provided on a vehicle (100), which is capable of travelling around a corner by tilting the vehicle body toward the turning direction, comprises a light source, an optical member by which the light emitted from the light source is directed forward from the lighting equipment to form a predetermined light distribution pattern (PL), and a control unit for adjusting the predetermined light distribution pattern (PL) according to the tilted state of the vehicle body. The control unit is configured to adjust a predetermined light distribution pattern (PL2) such that in a light distribution pattern (PL1) corresponding to when the vehicle body is tilted, no light is irradiated in a region located outside the light distribution pattern (PL) corresponding to when the vehicle body is in the vertical state. |
US11254382B2 |
Side-stand for motorcycle and manufacturing method thereof
A side-stand for a motorcycle enables both improvement in appearance and weight reduction by using a tapered pipe member. A side-stand for a motorcycle includes an elongate portion having a hollow structure, and a grounding portion. An outer shape of the elongate portion is tapered in appearance toward the grounding portion and, in a state in which the side-stand is unfolded, the elongate portion looks thinner as a whole in a side view than in a front view of a vehicle body. The elongate portion has a wall thickness on the distal end side equivalent to or smaller than a wall thickness on a proximal end side. The elongate portion is formed by increasing a diameter of a distal end side inner peripheral portion of a round pipe member by cutting, and then swaging an outer peripheral portion to reduce the diameter and obtain a tapered shape. |
US11254373B2 |
Aerodynamic systems and fairings with fairing caps
A fairing assembly adapted to control flow proximate to a vehicle wheel, the fairing assembly having an aerodynamic outer surface to direct flow. The fairing assembly comprises a fairing having a fairing outboard surface. The assembly further comprises a fairing cap coupled to the fairing to cover at least a portion of the fairing outboard surface. |
US11254369B2 |
Vehicle body joint structure
A vehicle body joint structure is disclosed. The vehicle body joint is configured such that elements configured to connect pillars of a vehicle body can be easily shared by various kinds and designs of vehicles, thereby being capable of securing assemblability of elements including the pillars while achieving enhancement in strength and rigidity. |
US11254362B2 |
Vehicle rocker with load transferring spacer
A vehicle including a rocker extending in a vehicle longitudinal direction having a first surface and a second surface, at least one crossmember extending in a vehicle width direction from the first surface of the rocker, and at least one spacer coupled to the second surface of the rocker, the at least one spacer being in line with the at least one crossmember. |
US11254359B1 |
Leg assembly for construction machine
A leg assembly includes a guide tube, a power drive coupled to a flange of the guide tube, a steering ring coupled to the power drive, a tube weldment coupled to the steering ring, and a hydraulic actuator coupled within the guide tube and within the tube weldment. The power drive includes a slew drive or a hydraulic cylinder steering assembly. The tube weldment is translated through the power drive by the actuator. To achieve a minimal width, the tube weldment includes a keyway. The steering ring includes a key by which relative rotational movements may be imparted to the keyway. The steering ring is rotated by the power drive. Thus, the guide tube may be rotated relative to the tube weldment. |
US11254356B2 |
Vehicle control system
The vehicle control system is applied as a system of a vehicle mounted with an EPS device having an electric motor driven to control the steering angle. The vehicle control system includes a controller configured to perform steering control for controlling an energization of the electric motor to control the steering angle of the wheels. When the wheels are held after being steered by a specific steering in the steering control, the controller performs a steering return process in which the wheels are turned back and held in a direction opposite to a steering direction of the specific steering. And during a stationary steering-holding in which the steering angle is held and the vehicle is stopped, the controller performs an energization suppression process for reducing energization to the electric motor to be smaller than the energization before the stationary steering-holding. |
US11254355B2 |
Electronic control device, control method, and non-transitory computer readable medium
An electronic control device controls an electronic power steering apparatus including a motor configured to assist steering of a steering wheel provided in a vehicle and a torque sensor configured to detect a steering torque applied to the steering wheel. The electronic control device includes: a torque current control unit that sets a first current command value to be supplied to the motor according to a value of the steering torque applied to the steering wheel; a differential control unit that calculates a torque differential value as a differential value of the steering torque and sets a second current command value according to the torque differential value and a rotation speed of the motor; and a command value calculation unit that calculates a motor current command value to be supplied to the motor based on the first current command value and the second current command value. |
US11254354B2 |
Method and apparatus for controlling motor of electric power assisted steering system
A motor control method for controlling a motor of an electric power assisted steering system includes: generating a low pass torque signal and a high pass torque signal, respectively; generating a low frequency assist torque signal using the low pass torque signal and the vehicle speed; generating a high frequency assist torque signal using a high pass torque signal and the vehicle speed; generating a torque command signal using a sum of the low frequency assist torque signal and the high frequency assist torque signal; and generating a voltage output signal for driving the motor using the torque command signal. |
US11254349B2 |
Linear worm and worm gear assembly
A power steering assembly includes a first housing containing a worm gear operatively coupled to a steering shaft, the worm gear rotatable about a worm gear axis. The power steering assembly also includes a second housing containing an electric motor and a worm arranged to engage the worm gear. The power steering assembly further includes a worm gear axis bearing disposed between the worm gear and an inner surface of the first housing, the worm gear axis bearing protruding from the second housing to position the first housing relative to the worm gear axis. |
US11254343B1 |
Steering wheels having an adjustable coefficient of friction
A vehicle system including one or more sensors, a steering wheel including a rim and an adjusting mechanism for adjusting a coefficient of friction between a surface of the rim and a driver's hand, and a controller configured to determine whether a deviation factor between a target path and an actual path based on the one or more sensors exceeds a threshold deviation, send a first signal to the adjusting mechanism for operating to a first state in response to determining that the deviation factor exceeds the threshold deviation, the coefficient of friction being decreased when the adjusting mechanism is in the first state, and send a second signal to the adjusting mechanism for operating to a second state in response to determining that the deviation factor does not exceed the threshold deviation, the coefficient of friction being increased when the adjusting mechanism is in the second state. |
US11254342B2 |
Delivery sled brake system
A pallet sled includes a base and a plurality of tines extending forward from the base. At least one of the plurality of tines includes a wheel supporting the tine away from the base. A brake assembly is positioned adjacent the wheel to selectively brake the wheel. The brake assembly may include a drum adjacent the wheel. Alternatively, the brake assembly may include a brake shoe selectively directly contacting the wheel to brake the sled. |
US11254338B2 |
Guideway mounted vehicle localization and alignment system and method
A system comprises a first sensor on a first end of a vehicle and an on-board controller coupled to the first sensor. The first sensor is configured to detect a radio frequency (RF) signature of a marker along a guideway. The first sensor is a radar detection device. The on-board controller is configured to determine a first position of the vehicle on the guideway or a first distance from the position of the vehicle to a stopping location along the guideway based on at least the RF signature received from the first sensor. The marker is a metasurface plate comprising a first diffused element, a first retroreflector element, a first absorbing element and a second diffused element between the first retroreflector element and the first absorbing element. |
US11254337B2 |
Determining location of a rail vehicle based on a radio frequency signal
A system for determining a location of a rail vehicle based on a radio frequency (RF) signal includes at least one processor programmed or configured to receive an RF signal transmitted by at least one radio transmitter device, where the RF signal includes location data associated with the location of the at least one radio transmitter device, determine a location of the at least one radio transmitter device based on the location data associated with the location of the at least one radio transmitter included in the RF signal, and determine a location of a rail vehicle based on the location of the at least one radio transmitter device. A method and computer program product are also disclosed. |
US11254336B2 |
Rail flaw detector
A rail flaw detector is configured for locating flaws in rails of a railroad track and for use with a vehicle travelling on the railroad track. The detector includes at least one signal applicator configured for applying ultrasonic signals to the rail and for receiving return signals; a mechanical subsystem connected to the applicator and to the vehicle and configured for maintaining the at least one signal applicator in operational position on the track. A human-machine interface is connected to the at least one signal applicator, is configured to control the detector and to monitor sensed rail condition. In one embodiment, the human-machine interface includes a schematic display of the rail being monitored and at least one touch screen control for controlling the mechanical subsystem and the at least one signal applicator. |
US11254333B2 |
Electronic control device, vehicle control method, and vehicle control program product
An electronic control device acquires at least one of subject vehicle information, surrounding environment information, and road information, detects an abnormality that has occurred in a vehicle during an autonomous driving based on a first travel plan, identifying a cause of the abnormality based on at least one of a content of the abnormality, the subject vehicle information, the surrounding environment information, and the road information, determines a situation around the vehicle based on at least one of the subject vehicle information, the surrounding environment information, and the road information, determines a target stop position for stopping the vehicle in a stoppable location based on the cause of the abnormality and the situation around the vehicle, and changes the first travel plan to a second travel plan for stopping the vehicle to the target stop position. |
US11254331B2 |
Learning method and learning device for updating object detector, based on deep learning, of autonomous vehicle to adapt the object detector to driving circumstance, and updating method and updating device using the same
A method for updating an object detector of an autonomous vehicle to adapt the object detector to a driving circumstance is provided. The method includes steps of: a learning device (a) (i) inputting a training image, corresponding to a driving circumstance, into a circumstance-specific object detector to apply (i-1) convolution to the training image to generate a circumstance-specific feature map, (i-2) ROI pooling to the circumstance-specific feature map to generate a circumstance-specific pooled feature map, and (i-3) fully-connected operation to the circumstance-specific pooled feature map to generate circumstance-specific object detection information and (ii) inputting the circumstance-specific feature map into a circumstance-specific ranking network to (ii-1) apply deconvolution to the circumstance-specific feature map and generate a circumstance-specific segmentation map and (ii-2) generate a circumstance-specific rank score via a circumstance-specific discriminator; and (b) training the circumstance-specific object detector, the circumstance-specific deconvolutional layer, the circumstance-specific convolutional layer, and the circumstance-specific discriminator. |
US11254323B2 |
Localization error monitoring
Localization error monitoring using vehicle state information is described. A computing system associated with a vehicle may determine a current state of the vehicle, such as a location, position, orientation, velocity, acceleration, or the like. The vehicle computing system may determine one or more metrics associated with the state of the vehicle. The metrics may include a variance associated with the state, a residual associated with a measurement corresponding to the state, or a correction factor applied to correct an input error. The computing system may determine whether the metric exceeds a threshold value. Based on a threshold exceedance, the computing system may determine one or more errors associated with a state of the vehicle. The vehicle computing system may control the vehicle based on the one or more errors. |
US11254320B2 |
Systems and methods for selective driver coaching based on driver efficiency
Systems and methods of selective driver coaching are provided. Driver coaching systems learn the characteristics of a deceleration event. With the goal of increasing recouped energy while operating a hybrid electric vehicle (HEV), driver coaching systems predict when the HEV can begin coasting at the start of the deceleration event. In this way, the amount of time during which regenerative braking can be applied may be increased. Coaching cues are provided to the driver so that the HEV can be operated in way that achieves the goal of increasing recouped energy. However, engaging in excessive regenerative breaking can negate its advantages if the amount needed to reaccelerate the HEV to a cruising/steady speed is too great. Selective driver coaching provides coaching cues only if the operating efficiency of the HEV exceeds the operating efficiency of the HEV when controlled by the driver without coaching cues. |
US11254315B2 |
Friction adaptive vehicle control
A system control a vehicle using a friction function describing a friction between a type of surface of the road and a tire of the vehicle as a function of a slip of a wheel of the vehicle. The parameters of each friction function include an initial slope of the friction function defining a stiffness of the tire and one or combination of a peak friction, a shape factor and a curvature factor of the friction function. Upon estimating a slip and a stiffness of the tire, the system selects from the memory parameters of the friction function corresponding to the current stiffness of the tire, determines a control command using a value of the friction corresponding to the slip of the tire according to the friction function defined by the selected parameters, and submits the control command to an actuator of the vehicle. |
US11254313B2 |
Travelling control apparatus
A travelling control apparatus includes a preceding vehicle information acquiring unit acquiring a preceding vehicle travelling speed pattern indicating a travelling speed change of a preceding vehicle; an energy efficiency index calculation unit calculating an energy efficiency index indicating a degree of improvement in an energy efficiency of the vehicle, in the case where the vehicle travels based on an own vehicle travelling speed pattern indicating a travelling speed change of the vehicle when the vehicle travels tracking the preceding vehicle; a compatibility index calculation unit calculating a compatibility index indicating a degree of compatibility between the vehicle and a following vehicle based on a travelling speed of the vehicle and the following vehicle; and a control unit performing a coasting travel determination determining whether to perform a coasting travel of the vehicle based on a degree of the energy efficiency index and the compatibility index. |
US11254311B2 |
Lateral adaptive cruise control
A system for lateral adaptive cruise control for use in a vehicle includes a main body, a power source, and a brake. The system further includes an input device to receive an adaptive cruise control request. The system further includes an object sensor to detect lateral object data. The system further includes an ECU designed to determine a velocity of the lateral object or a relative distance to the lateral object based on the lateral object data, determine a lane entrance event corresponding to the lateral object traveling towards a current lane occupied by the main body based on the at least one of the velocity of the lateral object or the relative distance to the lateral object, and control at least one of the power source or the brake to adjust a current speed of the main body based on the lane entrance event. |
US11254309B2 |
Cruise control system and method for vehicle
A cruise control system capable of: determining, by a controller, whether the vehicle is in a cruise mode-on state; determining, by the controller, an operation mode of the vehicle selected by a driver; and when it is determined that the vehicle is in the cruise mode-on state, performing, by the controller, cruise control of the vehicle for the operation mode selected by the driver, and a method therefor. Herein, the operation mode includes an eco mode which performs driving control prioritizing fuel consumption reduction. |
US11254307B2 |
Damage reduction device, damage reduction method, and program
A damage reduction device according to an embodiment of the present technology includes an input unit, a prediction unit, a recognition unit, and a determination unit. The input unit inputs status data regarding a status in a moving direction of a moving body apparatus. The prediction unit predicts a collision with an object in the moving direction on the basis of the status data. The recognition unit recognizes whether the object includes a person. The determination unit determines, when the collision with the object is predicted and it is recognized that the object includes a person, a steering direction of the moving body apparatus in which a collision with the person is avoidable, on the basis of the status data. |
US11254302B2 |
Stabilized real time trajectory optimization for hybrid energy management utilizing connected information technologies
A vehicle control method in a hybrid electric vehicle including an internal combustion engine, a battery, an electric motor, and a control unit. The method includes estimating an estimated vehicle velocity trajectory, estimating an initial engine power trajectory, simulating state of charge of the battery with the vehicle velocity trajectory and the initial engine power trajectory, estimating an initial terminal co-state value, simulating backward co-state dynamics using the state of charge and vehicle velocity trajectory, to obtain a resulting co-state trajectory. The co-state trajectory is used to solve a minimization control and propagate state of charge dynamics forward in time. The method includes updating control and the co-state trajectory, adjusting the terminal co-state value, and controlling a usage of the battery and the internal combustion engine. The method can be performed to optimize the engine power trajectory to minimize fuel consumption in real time. |
US11254298B2 |
System and method for compensation of turbo lag in hybrid vehicles
A system and method for compensation of turbo lag in hybrid vehicles is disclosed. The system identifies a zero boost power limit of the engine and a torque curve power limit. A turbocharger dynamic model is then developed based on measurements of the input engine power and the output max available engine power. The model is used to determine an overall propulsion power limit based on the combination of the engine and motor in operation. A power request by the driver may then be limited to the overall propulsion power limit to compensate for the effect of the turbocharger when propelling the vehicle using both the engine and motor and better simulate the engine-only response. |
US11254296B2 |
Method and a system for estimating the water content of brake fluid in a brake system
A method for estimating water content of brake fluid in a brake system including brake calipers and a brake fluid container, the brake calipers and the container each including a sensor configured to detect a water content of the brake fluid, the method including: arranging the brake system in a controlled environment; for a predetermined time period, exposing the brake system to a controlled temperature and humidity such that an increase in water content in the brake fluid is accelerated; determining the water content of the brake fluid in the brake fluid container and in each brake caliper as a function of time; and based on the determined water content as a function of time, establishing a model describing the relation between the water content of brake fluid in a brake caliper and the water content in the brake fluid in the brake fluid container. |
US11254292B2 |
Coupling clip, wiper lever, and wiper blade
A coupling clip includes a clip body that includes a wiper lever anchor portion to be anchored to a coupling shaft provided at a wiper lever assembly supporting a blade rubber, and a wiper arm anchor portion for anchoring a wiper arm. The coupling clip also includes a damper member that is attached to the clip body. When the wiper lever assembly is displaced with respect to the clip body, the damper member is deformed between the wiper lever assembly and the clip body. |
US11254285B2 |
Apparatus for preventing forcible separation of shift cable
An apparatus is provided to inhibit forcible separation of a shift cable 100 coupled to a shift lever 220 by a cover member 300 combined with a shifting device 200 which includes a shift lever housing 210 and the shift lever 220, thereby preventing forcible changing of a current gear from a P-stage to a N-stage in a vehicle. Accordingly, it is possible to help prevent theft of the vehicle. |
US11254279B2 |
Curtain airbag apparatus
A curtain airbag apparatus may include: a cushion part disposed at the top of a pillar part; one or more guide members connected to the cushion part and configured to fix the cushion part to a vehicle body; and a cushion moving part connected to the cushion part, disposed between the guide members and the vehicle body, fixed to the guide members, and configured to deform the guide members to move the cushion part to an indoor side of the vehicle body, while inflated by gas injected from an inflator. |
US11254271B2 |
Shock-absorbing member
A shock absorbing member of the present disclosure is a shock absorbing member including a first hollow member (11) and a second hollow member (12) that are made of aluminum alloy and are weld joined to each other, in which a weld material and weld beads (W) do not project from a side on which a joined surface between the first hollow member (11) and the second hollow member (12) is located. |
US11254268B2 |
All-terrain vehicle and wheel speed signal collecting device
An outer ring of an inner joint of the constant speed transmission shaft is provided with a vehicle speed sensor rotating synchronously with the inner joint, and the drive axle is fixedly equipped with a signal collecting device opposite to the vehicle speed sensor and configured to monitor a rotation speed signal of the vehicle speed sensor. The inner joint of the constant speed transmission shaft transmits torque during the running of a vehicle, and through monitoring a rotation speed of the inner joint, the rotation data of rear wheels can be obtained. By mounting the vehicle speed sensor on the inner joint and fixing the signal collecting device on the drive axle for monitoring the rotation speed signal of the vehicle speed sensor, the signal reading is stable, which facilitates the maintenance, reduces the cost, and can satisfy the environmental requirements. |
US11254263B2 |
Vehicular vision system
A vehicular vision system includes a plurality of cameras mounted at the vehicle and having respective fields of view exterior of the vehicle. The cameras include a CMOS image sensor and a serial data interface configured for transmission of captured image data to an image processing system via a serial data bus linking the respective camera to the image processing system, which processes the transmitted captured image data. The vehicular vision system transmits data to the cameras via the respective serial data bus linking the respective camera to the image processing system. The vehicular vision system activates at least one camera of the plurality of cameras (i) responsive to a gear position of the vehicle, (ii) based on situational analysis information derived from the image processing system, or (iii) based on a driving condition. |
US11254261B2 |
Method for forming an emergency lane on a multi-lane road and transportation vehicle having an apparatus for carrying out the method
A method for forming an emergency lane on a multi-lane road on which multiple transportation vehicles are located on at least two parallel driving lanes and on which at least one emergency vehicle is located, wherein the emergency vehicle is connected to more than one of the transportation vehicles via a wireless communications connection to exchange data and the transportation vehicles are prompted to form an emergency lane via the wireless communications connection. A transportation vehicle having an apparatus for implementing the method. |
US11254256B2 |
Method for detecting misadjustments of the cut-off line of a headlamp
A method for detecting misadjustments of a headlamp of a vehicle and to a device for this purpose. It is provided that the vehicle is provided with a detector with which at least one light signal of another road user is detected, and wherein the vehicle is equipped with a control unit with which light signal information of the detector is captured and by means of which adjustment information for correcting the misadjustment of the headlamp is output as a function of the captured light signal information. |
US11254254B2 |
Loading and unloading systems and methods
Methods and systems are provided for loading and unloading an item onto a vehicle. In one embodiment, a system includes: a loading system configured to receive a locker configured to store the item; a shuttle transfer system configured to transfer the locker to a storage position within the vehicle; and a swing arm system that couples to the loading system and the shuttle transfer system, the swing arm system configured to adjust a position of the loading system relative to the vehicle. |
US11254251B2 |
Grab handle and human body standing assist device
A grab handle includes a first shell, a second shell, and a display member between the first shell and the second shell. The first shell has a first accommodating portion and a first fixing mechanism. The second shell has a second accommodating portion and a second fixing mechanism. The grab handle is configured to, through a cooperation of the first fixing mechanism and the second fixing mechanism, fix the first shell and the second shell to each other and form an accommodating space by the first accommodating portion and the second accommodating portion together for accommodating the display member. |
US11254246B2 |
Decorative sheet
In a decorative sheet, a base material has a concave portion on a front face. The concave portion includes a bottom surface. The bottom surface includes a first surface, a second surface and a third surface. A depth dimension of the first surface is a first value. The depth dimension is a dimension from the front face of the base material along a thickness direction of the base material. The depth dimension of the second surface is a second value which is smaller than the first value. The third surface is a surface which is connected with the first surface at a back side of the thickness direction, and is connected with the second surface at a front side of the thickness direction. |
US11254245B2 |
Vehicle seat with inclinable seatback
A vehicle seat comprising a seatback pivoting relative to a frame around the first transverse axis, a seat cushion pivoting relative to the seatback around a second transverse axis, a link pivoting relative to the seat cushion around a third transverse axis, wherein the link is further pivoting relative to the frame around a fourth transverse axis, a mechanism for releasing the angular position of the seatback relative to the frame around the first transverse axis, and an actuator, attached under the seat cushion. The angular position of the seatback relative to the frame released, the actuator commands a movement of the link relative to the seat cushion and consequently of the seatback relative to the seat cushion, from a comfort position of the seat to a flat floor position. |
US11254239B2 |
Vehicle power controller, system including the same, and method thereof for smart key authentication
A vehicle power controller includes a processor capable of switching a power source of a vehicle based on whether a user rides in the vehicle, or whether a brake input occurs. The processor determines whether the user rides in the vehicle based on whether a smart key is authenticated in an interior of the vehicle, whether a door of the vehicle is opened or closed, or whether the user is seated in a seat. |
US11254238B2 |
Occupant position detection with active electric field sensor
A vehicle seating assembly comprises a seat including a back having an array of at least two electrodes arranged in the back such that a master electrode has an electric field being greater than an electric field of each of the other electrodes within the array to detect a total change in capacitance from the array. A controller is responsive to a change in capacitance calculated from the master electrode being greater than a first threshold and each of the other electrodes in the array being greater than a second threshold and outputs occupant movement data indicative of a first status of the seat to a vehicle control sub-system. |
US11254237B2 |
Method and system for operating a fuel cell system
The invention relates to a method and to a system for operating a fuel cell system (22) and at least one sub-system (30) of the fuel cell system (22). According to the invention, these are arranged in a vehicle (10), wherein the energy for a drive train (12) of the vehicle (10) can be drawn both from the fuel cell system (22) and from an alternative energy store (26). The method comprises the following method steps: first, the number and duration of shut-down and/or stop phases of the vehicles (10) in a defined time interval in a first vehicle state (86) or in a second vehicle state (88) is determined based on vehicle state-specific learning functions (90, 112). Operating parameters of the fuel cell system (22) and of the at least one sub-system (30) of the fuel cell system (22) are then adjusted in dependence on the determined number and duration of shut-down and/or stop phases of the vehicle (10). |
US11254228B2 |
Cover module of charging port for electric vehicle
A cover module of a charging port for an electric vehicle includes a panel coupling body comprising a charging housing fixed to an inner panel of a vehicle body of the electric vehicle to form a mounting hole, and a side outer coupled to face the inner panel fixed to the charging housing so that the mounting hole formed by the charging housing and the inner panel is maintained, and a cover main body formed in a shape corresponding to the mounting hole, provided with a plurality of hooks along an edge thereof to cover the mounting hole, and coupled to the panel coupling body by the hooks. |
US11254225B2 |
Managing vehicle information
A system includes a computing device for receiving information representative of activities of an operating first vehicle that includes a propulsion system. The computing device is configured to produce one or more control parameters from the received information in combination with information received from other vehicles, and, provide the one or more control parameters to control operations of a second vehicle. |
US11254223B2 |
Operating mode optimization for electric propulsion system with downsized DC-DC converter
An electric propulsion system includes a battery pack and a DC-DC converter. The converter has a bypass switch and semiconductor switches. A traction power inverter module (“TPIM”) rectifies a DC bus voltage on the voltage bus to produce an AC bus voltage. An electric machine is connected to the TPIM and energized via the AC bus voltage. A controller calculates required output power from the converter based on a requested operating mode, and speed and torque of the electric machine. When the output power exceeds a threshold, the bypass switch closes to bypass the converter. When the output power is less than the threshold, the controller uses a minimum loss voltage from a loss map as a target control voltage of the converter to optimize efficiency of the electric propulsion system. |
US11254219B2 |
Systems and methods for maintaining attitude control under degraded energy source conditions using multiple propulsors
A system for maintaining attitude control under degraded or depleted energy source conditions using multiple electric propulsors includes a plurality of propulsors, at least an energy source providing electric power to the plurality of propulsors and a vehicle controller communicatively coupled to each propulsor and configured to calculate initial power levels for the plurality of propulsors, the initial power levels including an initial power level for each propulsor, determine an energy output capacity of the least an energy source under load, calculate, by the vehicle controller, an aggregate potential demand of the plurality of propulsors as a function of the initial power levels, determine that electric potential is insufficient to match the aggregate potential demand, and for each initial power level generate a reduced power level, the reduced power level less than the initial power level and direct a corresponding propulsor to consume electrical power at the reduced power level. |
US11254216B2 |
Control system and method for controlling a torque generator
The invention relates to a control system for controlling a torque generator of a vehicle. The control system is configured to receive one or more electrical signals indicative of a surface indicator; receive one or more electrical signals indicative of a deceleration demand; select a surface type from a plurality of predetermined surface types based on said one or more electrical signals indicative of a surface indicator; determine a target vehicle deceleration in dependence on the selected surface type; determine, based on said one or more electrical signals indicative of a deceleration demand, a requirement to decelerate the vehicle; and in dependence on determining said requirement, output a control signal to the torque generator. The control signal is configured to cause the torque generator to provide the target vehicle deceleration. |
US11254215B2 |
Isolation resistance measurement of power system in vehicle
This disclosure describes techniques for separately determining isolation resistances from nodes of a power system of an electric vehicle (EV) to a chassis of the EV. Processing circuitry may determine a first isolation resistance between a first node of the power system in the EV and a chassis of the EV, determine a second isolation resistance between a second node of the power system in the EV and the chassis of the EV, determine that the first isolation resistance or the second isolation resistance is less than a threshold resistance, and output information based on the determination that the first isolation resistance or the second isolation resistance is less than the threshold resistance. |
US11254201B2 |
Work vehicle
A work vehicle of the invention includes: a pair of right and left front wheels disposed in a front part of the vehicle body; a pair of right and left rear wheels disposed in a rear part of the vehicle body; a side wall disposed at an outer end part of one side in a right-left direction of the vehicle body; and a radiator disposed between the front wheels and the rear wheels in a side view and on an inner side relative to the side wall in a plane view, wherein the radiator is disposed with an air-suction surface thereof facing toward the side wall to form an air-suction opening in a bottom part of a space between the air-suction surface and an inner surface of the side wall, and wherein a dust-proof body protruding downward to a lower level than a level of a lower end of the vehicle body is disposed on at least one of: a front side of the air-suction opening and a rear side of the front wheels; and a rear side of the air-suction opening and a front side of the rear wheels. |
US11254200B2 |
Vehicle drive device
A vehicle drive device includes: rotary electric machine; rotor support member; friction engagement device disposed at position on inner side in radial direction with respect to a rotor and at which friction engagement device overlaps rotor as viewed in radial direction along radial direction; and a first and second bearing that rotatably support rotor support member. Friction engagement device has a first and second engagement device disposed side by side in axial direction. First piston portion of first engagement device and a second piston portion of second engagement device are disposed separately on both sides in axial direction across a first and a second friction member. First bearing is disposed at a position at which first bearing overlaps first piston portion as viewed in the radial direction. Second bearing is disposed at a position at which second bearing overlaps second piston portion as viewed in the radial direction. |
US11254197B2 |
Tour bus
A tour bus includes a vehicle body, a front door, a rear door, a plurality of wheels, a luggage compartment door and a movable placing portion. The front door, the rear door and the luggage compartment door are all disposed at one lateral side of the vehicle body, with the luggage compartment door between the front door and the rear door. The wheels connected individually to a bottom of the vehicle body are used for displacing the vehicle body. The movable placing portion is foldably disposed in a storage area of the vehicle body. The movable placing portion includes a placing platform and a supportive structure. The placing platform can protrude out of the storage area of the vehicle body. The supportive structure is pivotally connected with the placing platform, and the supportive structure supports the placing platform while the placing platform is moved out of the vehicle body. |
US11254191B2 |
Air conditioning register
An air conditioning register includes: a downstream side fin; an upstream side fin; an operation knob; and a fork including a pair of transmission pieces, and connected to the operation knob. A transmission shaft is provided in the upstream side fin, and is interposed between the pair of transmission pieces. The transmission shaft is provided with a stopper that regulates further displacement of the fork. A surface of the stopper is an inclined surface that is inclined with respect to a center axis of the transmission shaft so as to be located outside in a radial direction centering on the center axis of the transmission shaft as approaching an end of the transmission shaft. An inclination angle of the inclined surface with respect to the center axis of the transmission shaft is an angle equal to or greater than 9° and equal to or less than 14°. |
US11254189B2 |
Electric heating device
An electric heating device may heat an air flow through a duct of a ventilation, heating and/or air-conditioning installation of an automotive vehicle. The heating device may include at least one heating module that is contained in a heating body. The heating body may include a housing for controlling and supplying electrical power to the at least one heating module. The housing may include, in its interior, a printed circuit board from which a power supply connector and a control connector protrude. The housing may also include a power supply opening such that the power supply connector emerges from the housing and a control opening such that the control connector emerges from the housing. The housing may include a skirt that protrudes in parallel to the control connector on the periphery of the control opening. The skirt may be formed as a single part with the housing. |
US11254181B2 |
Forecarriage of a rolling motor vehicle with roll control
The present invention relates to a forecarriage of a rolling motor vehicle with three or four wheels, comprising: a forecarriage frame (16); at least one pair of front wheels (10′, 10″) kinematically connected to each other and to the forecarriage frame by a kinematic roll mechanism (20) which enables the same to roll in a synchronous and specular manner; a roll control system (100) comprising a rod (110) having a first (111) and a second end (112) opposite each other which connect by means of hinging means (101′, 101″; 102′, 102″) a first (60) and a second anchoring portion (60) of forecarriage (8) directly to each other. At least one of said first and second anchoring portions is subject to roll movements of said two front wheels. The hinging means are configured to passively follow the movements of the two anchoring portions. The hinging means (101′, 101″) at the first end of the rod comprise at least a first roll hinge (101′) which has its hinge axis substantially orthogonal to a rolling plane of the two front wheels and is connected to the first anchoring portion. The roll control system comprises a first damper device suitable to dampen—in a predetermined angular range—the rotation movements of the rod with respect to the first roll hinge at the first end (111). The above angular range corresponds to the angular roll range of the rod. |
US11254177B2 |
Hollow coil spring and suspension device for vehicle
A hollow coil spring is made of a hollow wire in which a terminal sealed portion is formed on an end portion of the wire. The terminal sealed portion has a rotationally symmetric shape in which an axis passing through the center of the wire is the symmetric axis. The hollow coil spring includes an end wall portion, and an end face arc-shaped curved surface. The end wall portion includes an end face perpendicular to the axis. A distal-end-center closure portion is formed on the axis at the center of the end wall portion. A spring seat includes a base member and a sheet member. An end turn portion of the hollow coil spring is in contact with the sheet member. The end face of the end turn portion is opposed to a stopper wall of the spring seat. |
US11254174B2 |
Machine for mounting and/or removing vehicle wheels, in particular truck wheels
The present invention regards a machine for mounting and/or removing tyred wheels for vehicles including a framework, means for driving a wheel in rotation, a first arm extending or supported by the framework and a first mounting and/or removal tool supported by the first arm. |
US11254172B2 |
Tire pressure sensor with elastic telescopic valve assembly
The invention relates to the field of tire pressure detection technologies, and discloses a tire pressure sensor including: a valve assembly including a mounting portion and an elastic telescopic structure mounted to the mounting portion, the elastic telescopic structure elastically extending and retracting on at least one side of the mounting portion; a sensor assembly having two opposite clamping surfaces, at least one of the two clamping surfaces being provided with a locking hole, the mounting portion being located between two of the clamping surfaces, and the elastic telescopic structure being inserted into the locking hole. After the elastic telescopic structure is shortened, the mounting portion of the valve assembly may be inserted between the two clamping surfaces. When the mounting portion of the valve assembly is located between the two clamping surfaces, the elastic telescopic structure may be extended and inserted into the locking hole automatically, so that the valve assembly and the sensor assembly may be installed conveniently, and no additional tools are required. |
US11254171B1 |
Self contained tire inflator
An inflator disposed within a tubeless tire for inflating the tubeless tire. A rechargeable electric storage disposed within a tubeless for providing electricity. An electric air compressor is mounted on an inside surface of the rim of the tubeless tire within the pressure cavity of the tubeless tire. The electric air compressor and an air pressure sensor disposed within the tubeless tire runs by a controller. The electric air compressor has a compressed air inlet vented to atmosphere in a custom valve stem through a conventional hole of a valve stem in the rim of the tubeless tire. A motion activated power generator recharges the rechargeable electric storage. A short-range radio transmits measured pressure data for each tire to a central OBD module plugged into in the vehicle. The central OBD module connects through a smartphone indirectly or directly to a central server via a networked cellular radio tower. |
US11254169B2 |
Tread with concealed cavities comprising a wear indicator having improved visibility
A tire (1) comprising a tread (8), this tread comprising at least one channel (2), at least one wear indicator (3) disposed on the bottom of the channel (2), the wear indicator comprising a contact face (7) intended to come into contact with a road surface when the tire reaches a wear limit, the channel (2) comprising a texture (4) surrounding the wear indicator (3) and contrasting with the contact face (7) of the wear indicator. |
US11254168B2 |
Vehicle tire
The tread profile of a vehicle tire has a circumferential rib. Grooves are formed in the circumferential rib with a width, which increases along its entire extent, wherein the grooves are formed with a vertex point between a first portion and a second portion. The groove direction from the beginning to the vertex point is formed with a greater directional component in the circumferential direction than in the axial direction and between the vertex point and the entry into the circumferential groove is formed with a greater directional component in the axial direction than in the circumferential direction. The groove is formed in the first portion with a depth T1, which increases continuously from the beginning over the first portion up to reaching its maximum value T1max at the vertex point and is formed with a constant depth T2 in the second portion wherein T2≥T1max. |
US11254164B2 |
Tire comprising a tread
A tire has a tread comprising a rubber composition based on at least an elastomer matrix comprising more than 50 phr and up to 100 phr of a first diene elastomer bearing at least one SiOR function, R being a hydrogen atom or a hydrocarbon radical, and optionally, 0 to less than 50 phr of a second diene elastomer which is different from the first diene elastomer; a reinforcing filler predominately comprising a reinforcing inorganic filler, wherein the content of reinforcing inorganic filler is 20 to 200 phr; and a plasticizing agent comprising 5 to 100 phr of a liquid phosphate plasticizer having a glass transition temperature of less than −80° C. |
US11254162B1 |
Tire assembly and disassembly auxiliary device
A tire assembly and disassembly auxiliary device includes a base frame for loading a tire and a handle. The base frame includes a main bar member and two branch bar members. The main bar member is pivotally connected with a joint member. Each of the branch bar members has a front shaft seat at an end, a rear shaft seat having a rear wheel at an opposite end and a rotatable roller between the front shaft seat and the rear shaft seat. The rear shaft seat has a connecting member capable of movably connecting to the main bar member and being fixed to the main bar member through a positioning member. The handle connects with the joint member so as to pivot relative to the main bar member. A restricting member selectively connects with the handle and the main bar member in order to fix the handle. |
US11254160B2 |
Snap-on automotive wheel cover overlay with extended surround and method for manufacturing the same
An improved snap-on automotive wheel cover overlay with extended surround having hook-shaped members for the purpose of securing the wheel cover overlay of the present invention to a damaged manufacturer's wheel cover. The wheel cover overlay of the present invention is further secured by inserting a tension rotation device from the reversed position of a tire into a manufactured in wheel cover overlay tension tabs assembly, and having an extended surround covering the entire rim of a vehicle when installed there on. During manufacturing of the present invention, a three dimensional (3D) scanned imaging of the individual embodiment component parts is generated, after rigorous testing, and is transferred to an injection molding computer to generate the injection molding designed precisely corresponding to each individual component parts of the present invention. |
US11254158B2 |
Blanket manufacturing apparatus and blanket manufacturing method
The present specification relates to an apparatus for manufacturing a blanket, a method for manufacturing a blanket, a blanket manufactured using the same, a reverse offset printing roll provided with the blanket, and a reverse offset printing apparatus including the same. |
US11254153B2 |
Modifying control data packets that include random bits
A fluid ejection controller interface includes output logic to receive control data packets, each control data packet including a set of primitive data bits and a set of random bits. The fluid ejection controller interface includes counter logic to cause the output logic to output modified control data packets to a fluid ejection controller of a fluid ejection device. |
US11254150B2 |
Adjusting method for printing apparatus, and printing apparatus
An adjusting method for a printing apparatus includes a head configured onto perform printing on a medium, a winding shaft configured to wind thereon the transported medium, a shaft adjustment mechanism configured to adjust a position of the winding shaft, and a notification part configured to provide a notification, the method including a printing step for printing a scale onto the medium, a transporting step for transporting the scale to the winding shaft, an image-capturing step for image-capturing the scale, which is transported to the winding shaft, at two different locations of the medium in a direction along an axis of the winding shaft, a notification step for providing to the notification part a notification about a result based on a captured image of the scale, and an adjustment step for adjusting a position of the winding shaft in accordance with a result notified to the notification part. |
US11254141B2 |
Printing system
A printing system includes: a control unit; and a printing device including: a supply unit configured to be attached with a supply roll configured by an ink ribbon; a winding unit configured to be attached with a winding roll for winding the ink ribbon fed out from the supply roll; a ribbon motor configured to rotationally drive at least one of the supply unit and the winding unit; a thermal head configured to perform printing by heating the ink ribbon transported from the supply roll toward the winding roll by driving the ribbon motor; and a head drive source configured to move the thermal head. The control unit is configured to control the ribbon motor to decrease tension of the ink ribbon when the thermal head is moved in a first direction, in which the tension of the ink ribbon increases, with the head drive source. |
US11254137B2 |
Recording apparatus
A recording apparatus including a recording unit that performs recording by discharging a liquid on a medium transported in a transport direction, a liquid storage portion that is disposed on an apparatus front side in an apparatus depth direction and that includes a liquid container that contains the liquid discharged from the recording unit, and a maintenance unit that performs maintenance on the recording unit. In the recording apparatus, the maintenance unit is provided in an end portion area on a first direction side in a width direction, the width direction being a direction intersecting the depth direction, and the liquid storage portion is provided in an end portion area on a second direction side, the second direction side being a side opposite the first direction side in the width direction, the liquid storage portion extending in the depth direction to an occupying area of the maintenance unit. |
US11254132B2 |
Head chip, liquid jet head, and liquid jet recording device
There is provided a head chip and so on capable of achieving the reduction in power consumption and the improvement in print image quality while suppressing the manufacturing cost of the head chip. The head chip according to an embodiment of the present disclosure includes an actuator plate having a plurality of ejection grooves and a plurality of electrodes, a nozzle plate having a plurality of nozzle holes, and a cover plate having a wall part, a first through hole, and a second through hole. The plurality of nozzle holes includes a plurality of first nozzle holes arranged so as to be shifted toward the first through hole, and a plurality of second nozzle holes arranged so as to be shifted toward the second through hole. In a first ejection groove communicated with the first nozzle hole, a first cross-sectional area of a part communicated with the first through hole is smaller than a second cross-sectional area of a part communicated with the second through hole. Positions of both ends of the electrode along the extending direction of the ejection grooves are each aligned in the plurality of electrodes along a predetermined direction. |
US11254129B2 |
Head unit
There is provided a head unit including: at least two head modules, and at least one head module. The head unit further includes: a tank; a first and second tubes; and a joint unit including at least one first joint which includes a first port connected to the first tube and a second port connected to the second tube, and which relays the first tube and the second tube to each other. The first port of the at least one first joint extends in one side in a third direction orthogonal to the first direction and the second direction. |
US11254125B2 |
Liquid discharging head unit and liquid discharging apparatus
A first flow path is provided between the first layer and the second layer, a second flow path is provided between the second layer and the third layer, a filter chamber is provided inside the third layer, and the second layer is thinner than each of the first layer and the third layer. |
US11254116B1 |
Platen assembly for printing on face masks
A platen assembly for printing on face masks which includes a base member having a plurality of jig members mounted thereon. The base member has a top surface and a bottom surface, with its bottom surface operative to attach to a platen holding mechanism of a conventional direct to garment printer. Each of the jig members may be attached to the top surface of the base member and hold a single face mask in such a manner that it can be printed on. Edges of the base member and of each jig member include interface portions which allow portions of the face mask to be selectively threaded through to more effectively keep the face masks in place, being held smooth and taught. |
US11254115B2 |
Outlet structure
A build material container outlet structure (100) comprises: a connector (107) comprising an interface surface (116) and an adaptor to receive a nozzle structure (202) of an external aspiration system; and a retaining structure (128) to releasably hold the nozzle structure in an engagement position with the interface surface of the connector; wherein the retaining structure comprises one or more retaining elements (118-1, 118-2, 118-3) disposed in the connector to exert an attractive magnetic biasing force on the nozzle structure of the external aspiration system to releasably hold the nozzle structure in the engagement position with the interface surface of the connector. |
US11254108B2 |
Laminate structure for biocompatible barrier packaging
Biocompatible flexible laminate structure comprising an alternating stack of layers from polymers A and B or polymer blends AC and BD having the sequence -A-[B-A-]n- or AC-[BD-AC-]n with n from 4 to 36, wherein the layer thickness of layers A or AC and layers B or BD is less than 3 μm, wherein A and B are thermoplastic polymers and C and D are thermoplastic elastomers, at least part of the monomeric building blocks of polymer A, B or A and B are from renewable sources wherein the thermoplastic polymer B has functional barrier properties, wherein the amount of the thermoplastic elastomers C and D in the polymer blends AC and BD is each from 3 to 45 wt.-%, and polymer B and elastomer D are essentially incompatible. |
US11254103B2 |
Bullet-resistent insulating glazing unit
An insulating glazing unit may be configured to provide both visible transparency and bullet-resistance. The bullet resistant properties of the unit may be achieved through the combination and coordination of different materials forming the panes of the unit. For example, the insulating glazing unit may include multiple laminate panes separated by a spacer. Each laminate pane may include at least two transparent rigid substrates joined by a layer of laminate material. The laminate material used in one laminate pane may be different than the laminate material used in another pane. For example, one pane may utilize a laminate material that is soft and flexible. This may help absorb and dissipate the impact of a projectile. By contrast, another laminate pane may utilize a laminate material that is stiff and rigid. This may help provide a final stopping force to a projectile. |
US11254097B2 |
Barrier film laminate, method of producing the same, wavelength conversion sheet, backlight unit, and electroluminescent light-emitting unit
The present invention provides a barrier film laminate including a first barrier film that includes a first substrate layer and a first barrier layer formed on the first substrate layer, a second barrier film that includes a second substrate layer and a second barrier layer formed on the substrate layer, and an adhesive layer. In the barrier film laminate, the first barrier film is bonded with the second barrier film so that the first barrier layer faces the second barrier layer with the adhesive layer interposed therebetween. In one embodiment of the barrier film laminate, the adhesive layer is formed of an adhesive containing an epoxy resin, a curing agent having an amino group, and either a silane coupling agent having an epoxy group or a silane coupling agent having an amino group and two hydrolyzable functional groups. |
US11254091B2 |
Protective thermal sleeve for portable electronic devices and pharmaceuticals
Protective sleeves for portable electronic devices or thermally sensitive pharmaceuticals are provided. More particularly, embodiments relate to a protective sleeve that is capable of protecting a portable electronic device or a thermally sensitive pharmaceutical enclosed within from multiple environmental effects, including heat, cold, water, impact forces from being dropped, and germs and bacteria. In embodiments, provided is a protective sleeve comprising: an outer layer of material with a reflective surface; and an inner layer of material with a protective surface that can include an antimicrobial agent; wherein the outer layer of material and the inner layer of material are layered together and configured to receive a portable electronic device or thermally sensitive pharmaceutical. A thermal masking material and products thereof which can be used in a variety of applications where reduced visibility and heat detection is desired such as military, law enforcement, and hunting are also described. |
US11254090B2 |
Method for fabricating a spacer fabric composite having a pattern
The invention provides a method for fabricating a spacer fabric composite having a pattern, fabricating machine and composite fabricated by method thereof. The method comprises a film forming step, a patterning step, a laminating step and a hole opening step. |
US11254089B2 |
Lightweight inner dash
Moulded inner dash trim part for a vehicle comprising a porous fibrous layer comprising fibers and thermoplastic binder, and an air permeable foil laminated together wherein the fibers comprise conjugate frizzy fibers made of at least 2 sides with a difference between the two sides inducing an intrinsic permanent frizzy or curved shape in a random 3 dimensional form, and wherein the air permeable foil has an airflow resistance that is between 30-75% of the total airflow resistance of the trim part. |
US11254087B2 |
Micro-perforated glass laminates and methods of making the same
Some embodiments of present disclosure are directed to a micro-perforated glass or glass-ceramics laminate, comprising a first substrate laminated to a second substrate by a first polymer interlayer, wherein the first and the second substrates are independently selected from glass or glass-ceramics, and a plurality of micro-perforations, each of the plurality of micro-perforations extending through the first substrate, the first polymer interlayer, and the second substrate. Some embodiments are directed to methods of forming such micro-perforated glass or glass-ceramics laminates. |
US11254086B2 |
Packaging material for packaging of light-sensitive goods and method for producing said packaging material
A packaging material for packaging of light-sensitive goods, said packaging material comprising a first layer and a second layer, at least one hole penetrating said first layer and being covered by said second layer, and a light barrier, wherein said light barrier comprises a layer of ink being essentially nontransparent to light and provided on said second layer to at least partly cover said hole. The disclosure further relates to a method for providing a light barrier covering a hole in a packaging material as well as to a package for packaging of light-sensitive goods. |
US11254074B2 |
Apparatus and method for making radius composite gap filler
A die assembly for forming a composite gap filler, including a first die having a first portion which extends along a first central axis of the first die and has a first curved surface which has a radius which changes as the first curved surface extends about the first central axis. A second die a second portion which extends along a second central axis of the second die and has a second curved surface which has a radius which changes as the second curved surface extends about the second central axis. A third die defines a third wall member which extends about the third die and which changes in width dimension wherein with the first die abutting the second die and with the third wall member abutting the first and second dies, a closed gap is formed. |
US11254072B2 |
Fiber tow wrap resistant fiber placement head
A fiber placement head for applying a plurality of composite tape segments on a mold including one or more powered wheels that are configured to engage and move composite tape; and one or more elongated fingers that closely conform to or abut an outer surface of the powered wheel(s) such that a portion of the elongated finger(s) forms at least a portion of a lane path. |
US11254065B2 |
Support device for a tubular element for a welding apparatus and welding apparatus comprising the support device
A support device for a tubular element, includes a housing part configured to house, during use, the tubular element, and at least a mobile part for guiding and positioning the tubular element and for protecting the housing part. The mobile part is configured to assume at least a first position to access the housing part of the tubular element, in order to easily insert the tubular element into the housing part, and to assume at least a second position to retain the tubular element and to at least partly cover said housing part and the tubular element positioned therein. The mobile part includes a lever for passage from the first position to the second position and drivable by the tubular element during its insertion into the housing part. |
US11254062B2 |
Apparatus and system for fabricating an elastic nonwoven material
An apparatus for fabricating an elastic nonwoven material generally includes a rotary ultrasonic horn and a rotary anvil positionable in close proximity to the ultrasonic horn. The anvil has a face with a width and a circumferential axis. The face has a plurality of ridges each of which defines a plurality of interspaced lands and notches. |
US11254060B2 |
Systems and methods for determining tool paths in three-dimensional printing
The present disclosure provides methods and systems for printing a three-dimensional (3D) object. A method for printing a 3D object may comprise receiving a computer model of the 3D object in computer memory and generating a parametric representation of the computer model of the 3D object. Next, a first edge in a parametric representation of a curved surface of the computer model may be selected, and a 3D tool path may be generated at least in part by: (i) selecting a first set of points on the first edge; and (ii) computing coordinates of a second set of points on a second edge parallel to the first edge in the parametric representation, wherein the first edge and the second edge define the 3D tool path. Printing instructions may then be generated for printing at least a portion of the 3D object along the tool path. |
US11254059B2 |
System and method for additive manufacturing of skin-formulation applicators
Systems and methods suitable for making skin-formulation applicators through additive manufacturing are described. |
US11254058B2 |
Adjustable carriage and optimized bearing surface means
A three-dimensional printer with improved adjustment mechanisms for calibrating the orientation of the build platform and an extrusion assembly to optimize the accuracy of models deposited on the build platform. The printer includes a frame carrying an extrusion assembly proximate the top, and a carriage within. A build platform is mounted on the top of the carriage. Carriage adjustment mechanisms are provided at at least two corners of the carriage for calibrating the orientation of the build platform with respect to the X-Y plane. An extrusion assembly adjustment mechanism is provided at at least one end of the extrusion mechanism for calibrating the orientation of the extrusion mechanism with respect to the Y-axis. A height adjustment mechanism is provided for translating the carriage within the frame along the Z-axis. |
US11254056B2 |
Feeding mechanisms for 3D printers
In order to have ensure a proper dosing of a 3D printing system, it is disclosed a feeding mechanism for feeding build material to a surface that comprises: a receptacle to receive build material; and an outlet of the build material having a substantially quadrilateral opening with a first dimension and a second dimension orthogonal to one another; the outlet further comprising a third dimension orthogonal to the first dimension and the second dimension defining the height of the outlet, and the feeding mechanism being to selectively feed build material from the receptacle through the outlet onto a surface as the feeding mechanism moves along a travel direction over the surface, being such travel direction parallel to the first dimension of the outlet, the feeding mechanism further comprising an actuator to modify the magnitude of at least one of the second dimension or the third dimension outlet. |
US11254054B2 |
Exposure systems, printing systems, methods for additive manufacturing, compositions, and the use thereof
Printing systems, compositions suitable for the printing system, use of the compositions, methods for additive manufacturing, and exposure systems, all allowing for improved 3D manufacturing of products, include the exposure of layers of photopolymer material by two different wavelengths coming from LEDs. |
US11254052B2 |
Vatless additive manufacturing apparatus and method
An additive manufacturing apparatus includes: a build table, at least a portion of which is transparent, the build table defining a build surface; a material applicator operable to deposit a radio-energy-curable resin on the build surface; a stage positioned facing the build surface of the build table and configured to hold a one or more cured layers of the resin; one or more actuators operable to change the relative positions of the build table and the stage; a radiant energy apparatus positioned adjacent to the build table opposite to the stage, and operable to generate and project radiant energy on the resin through the build table in a predetermined pattern; a drive mechanism operable to move the build table so as to expose a new portion thereof for each layer; and material remover operable to remove remnants from the build surface. A method for using the apparatus is provided. |
US11254051B2 |
Build material containers
There is provided a 3D printing build material container (1). The container (1) comprises a reservoir (3) and a reinforcement structure (4). The reservoir is to hold build material. The reinforcement structure is attached to the reservoir at at least one selected location. The reservoir and reinforcement structure are to permit reconfiguration of the container from a relatively flat configuration to an in-use configuration in which the reservoir is tillable with build material. |
US11254048B2 |
Additive manufacturing of continuous fiber thermoplastic composites
Additive manufacturing systems and methods used for creating 3D parts from continuous-fiber reinforced composites such as, e.g., carbon-fiber or glass-fiber pre-impregnated tape are provided. The systems and methods lay tape in successive layers and cut each layer according to a 2D slice of a 3D CAD file. During the placement of each piece of tape, a laser welds the tape to other tape, eliminating the need for post-processing of each layer. By utilizing tape instead of large fiber-reinforced sheets, the systems and methods described herein reduce waste compared to known manufacturing techniques. |
US11254039B2 |
Apparatus and method for heating a side gate nozzle
An injection molding machine includes an edge gate nozzle with a nozzle body having a primary melt channel and a nozzle head having first and second secondary melt channels that feed melt to first and second nozzle tips. First and second heaters are disposed in the nozzle head to provide heat to the secondary melt channels. In some embodiments, the heaters are positioned adjacent to the secondary melt channels, with first heater is closer to the first secondary melt channel than to the second secondary melt channel. In some embodiments, the heaters are positioned adjacent to the nozzle tips, with the first heater closer to the first nozzle tip than to the second nozzle tip. In some embodiments, each heater is adjacent to both the respective nozzle tip and secondary melt channel. In some embodiments, each heater is individually controllable. |
US11254038B2 |
Injection unit, with closure pin, for the injection moulding of plastic material, with capacity to recover thermal dilatations and avoid leakage of the plastic material
Injection unit for injection molding of plastic material including: an injection nozzle; a closure pin; and a guide and cooling assembly, interposed between the back driving plate and the hot distribution plate, in turn comprising: a guide and seal element for guiding the axial motion of the closure pin; a cooling ring; and pressure means configured to press the cooling ring directly and against the back driving plate; wherein the guide and seal element is slidably coupled, at an upper end, with a central hole of the cooling ring, and is fixed integrally, at the other end, to the hot distribution plate; and the cooling ring is able to slide laterally with respect to the back driving plate to recover the differences in thermal expansion between the hot distribution plate and the back driving plate and to transmit heat from the guide and seal element towards the back driving plate. |
US11254037B2 |
Water-assisted injection molded cross-car beam
A method of forming a cross-car beam is provided. A composite is melted to form a viscous polymer. The polymer is injected into a mold. Pressurized fluid is injected into the mold to evacuate a portion of the viscous polymer from the mold and to form a channel therethrough. The remaining viscous polymer is cooled within the mold to form a cross-car beam. |
US11254035B2 |
Injection molded component and method of injection molding
An injection molded component includes a wall that has an inner wall surface and an outer wall surface. A sensor is molded into one of the inner wall surface and the outer wall surface. A channel is at least partially surrounding the sensor. |
US11254034B2 |
Mould and method for injection moulding a closure assembly
A mould for injection moulding a closure assembly having a cap and lid includes a first and second mould part moveable with respect to each other. The lid includes a nipple made from a first material. The cap includes a dispensing passage to be sealed by the nipple and is made from a second material. The mould includes a holder adapted for receiving a pre-formed body with the nipple. This holder holds the body and nipple in place in a closure cavity for moulding the closure assembly. The holder includes a core having a recess for receiving the nipple. The holder further includes a tube part for insertion into the tubular nipple. This tube part can be connected with a suction source. |
US11254032B2 |
Surface texturing for advanced polymers
Surface micro-texturing has been proven an effective way to reduce friction and wear for tribological applications. There is provided a low cost hot sintering method to apply micro-texturing on an advanced bearing polymer material. First, one face of the mold was micro-textured using a micro-casting method. Second, the cured Aromatic Thermosetting coPolyester (ATSP) powder was filled in the mold. Next, the filled mold was placed in a hot press for a hot sintering process. Finally, the textured bulk ATSP was cooled. The micro-textured ATSP bulk material was machined and compared with plain untextured material. The micro-textured material could effectively reduce friction at speeds lower than 2.46 m/s: 14% reduction in average. |
US11254029B2 |
Wafer dividing apparatus
A wafer dividing apparatus for dividing a wafer stuck to an adhesive tape and supported at an opening of a frame into individual chips along a scheduled division line is provided. The wafer dividing apparatus includes a cassette table movable upwardly and downwardly in a Z axis direction, a first carry-out/in unit that carries out the frame from the cassette placed on the cassette table or carry in the frame to the cassette, a first temporary receiving unit including a pair of first guide rails extending in the X axis direction and a guide rail opening/closing portion that increases the distance between the pair of first guide rails, a reversing unit including a holding portion that holds the frame and rotates by 180 degrees to reverse the front and back of the frame, and a transport unit that moves the reversed frame. |
US11254028B2 |
Systems and processes for accelerated carbonation curing of pre-cast cementitious structures
Systems for accelerated carbonation curing of a pre-cast cementitious structure may include an ejector and a curing chamber downstream of the ejector. The ejector may be operable to combine a lesser-pressure carbon dioxide containing stream from a carbon dioxide source with a greater-pressure steam to produce a mixed stream including at least steam and carbon dioxide. The mixed stream may have a pressure greater than the pressure of the lesser-pressure carbon dioxide containing stream. The curing chamber may be operable to receive the mixed stream from the ejector and contact the mixed stream with the pre-cast cementitious structure to cure the pre-cast cementitious structure. Processes for accelerated carbonation curing of pre-cast cementitious structures using the systems are also disclosed. |
US11254018B2 |
Industrial robot and a device for transferring media from the robot to a tool
The present invention relates to a device for transferring media from an industrial robot to a tool, and an industrial robot including the device. The device comprises a swivel adapter (1) having a body (5) including a first coupling unit (7) arranged in one end of the body for coupling the swivel adapter to the robot, and second coupling unit (9) arranged in an opposite end of the body for coupling the swivel adapter to the tool, and a distance element (13) having a lower portion (15) attached to the first coupling unit and an upper portion (17) attached to the second coupling unit, wherein the first and second coupling units are spaced apart from each other along a common central axis (C1) so that a gap (11) is formed between them. The lower portion of the distance element is disposed at a distance the periphery of the first coupling unit, and the second coupling unit is provided with a penetration hole (19) in communication with the gap (11). The upper portion (17) of the distance element is arranged so that a space is formed between the upper portion of the distance element (13) and the first coupling unit (7). The penetration hole is formed between the distance element and the second coupling unit (9). The penetration hole is partly surrounding the distance element. The penetration hole extends an angle around the common central axis and in a curved direction around the distance element. |
US11254017B1 |
Mechanical positioning structure
A mechanical positioning structure includes a first positioning mechanism, a fixing post arranged through a central axis of the first positioning mechanism, a first driving mechanism, a second positioning mechanism rotationally arranged on the fixing post and coupled to the first driving mechanism, a second driving mechanism, and a platform. One end of the first driving mechanism is fixed on the fixing post. Another end of the first driving mechanism is slidably arranged on the first positioning mechanism. The second driving mechanism is arranged on the second positioning mechanism. The platform is arranged on the second driving mechanism. The first driving mechanism drives the second positioning mechanism to move on a surface of the first positioning mechanism and rotate the second positioning mechanism around the fixing post. The second driving mechanism drives the platform to move on the second positioning mechanism. |
US11254016B2 |
Joint mechanism, method for controlling the same, multi-arm device, and robot
The present invention relates to a joint mechanism (100), a method for controlling the joint mechanism (100), a multi-arm device (200) including the joint mechanism (100), and a robot. The joint mechanism (100) comprises: a base (4) having a pivot shaft (41); a swinging arm (1) having a first end (11) mounted on the pivot shall (41); a first driving member (2) and a second driving member (3) mounted on the pivot shall (41) for interacting with the swinging arm (1) through magnetorheological fluid; and a first electromagnetic component (22) and a second electromagnetic component (32), configured to change phase state of the magnetorheological fluid. The first driving member (2) and the second driving member (3) can selectively drive tire swinging arm (1) to rotate along a first direction or a second direction. |
US11254013B2 |
Interchangeable robot gripper base
Systems and methods of a robotic arm coupling for connecting a tool with a robotic arm are disclosed. In an embodiment, the robotic arm coupling includes: a mounting interface for mounting the robotic arm coupling on a robotic arm; a coupler interface on which differently actuated tools are releasably and interchangeably coupled; a fluid inlet port connected to an external fluid source to receive a pneumatic fluid; a plurality of interface fluid ports; at least one valve in fluid a communication with the fluid inlet port and settable to at least a first and a second operating state; and a suction device configured to apply a fluid suction pressure to an interface fluid port when a fluid pressure is provided to the suction device. |
US11254011B1 |
System and method for robotic resolution of scan alarm
Systems and methods are described, and an example system includes a transport bin configured to carry a baggage item and having spatial reference frame marking detectable by electromagnetic scan and by machine vision. The system includes a robotic arm apparatus at an inspection area, and includes a switched path baggage conveyor that, responsive to electromagnetic scan detection of an object-of-interest (OOI) within the baggage item, conveys the transport bin to the inspection area. The electromagnetic scan generates OOI geometric position information indicating geometric position of the OOI relative to the spatial reference frame marking. The robotic arm apparatus, responsive to receiving the transport bin, uses machine vision to detect orientation of the spatial reference frame marking, then translates OOI geometric position information to local reference frame, for robotic opening of the baggage item, and robotic accessing and contact swab testing on the OOI. |
US11254004B2 |
System identification of industrial robot dynamics for safety-critical applications
Embodiments of the present invention provide automated robotic system identification and stopping time and distance estimation, significantly improving on existing ad-hoc methods of robotic system identification. Systems and methods in accordance herewith can be used by end users, system integrators, and the robot manufacturers to estimate the dynamic parameters of a robot on an application-by-application basis. |
US11254001B2 |
Controller, control system and ladder program
To provide a controller capable of facilitating changing of the order of robot cells, a control system, and a ladder program. A master PLC includes a master input unit that receives a first input signal indicating the order of operation of robot cells, and a second input signal indicating work completion in the robot cells from each of the plurality of robot cells; a master output unit that outputs an output signal for instruction of operation to the robot cell specified on the basis of combination of the first input signals, and the second input signal according to the ladder program; and a storage unit that stores a plurality of the ladder programs corresponding to a plurality of patterns of the order of operation comprising at least some of the plurality of robot cells. |
US11254000B2 |
Machine teaching terminal, machine, non-transitory computer readable medium storing a program, and safety confirmation method for teaching machine
To provide a machine teaching terminal, a machine, a program, and a safety confirmation method capable of ensuring the safety of a worker without providing an additional device or the like. A machine teaching terminal communicably connected to a robot so as to be used for teaching the robot within a work area of the robot includes a touch panel display configured to accept input performed by a worker, an input detection part configured to detect input to the touch panel display, an abnormality detection part configured to detect an abnormal state on the basis of the detection by the input detection part, and an abnormal signal transmission part configured to transmit, in the case where the abnormality detection part detects the abnormal state, a signal indicating the abnormal state to the robot. |
US11253999B2 |
Machine learning device, robot control device and robot vision system using machine learning device, and machine learning method
A machine learning device includes a state observation unit for observing, as state variables, an image of a workpiece captured by a vision sensor, and a movement amount of an arm end portion from an arbitrary position, the movement amount being calculated so as to bring the image close to a target image; a determination data retrieval unit for retrieving the target image as determination data; and a learning unit for learning the movement amount to move the arm end portion or the workpiece from the arbitrary position to a target position. The target position is a position in which the vision sensor and the workpiece have a predetermined relative positional relationship. The target image is an image of the workpiece captured by the vision sensor when the arm end portion or the workpiece is disposed in the target position. |
US11253997B2 |
Method for tracking multiple target objects, device, and computer program for implementing the tracking of multiple target objects for the case of moving objects
A method for tracking multiple target objects, moving objects to be tracked being projected onto a grid map having grid cells, the method including the following tasks to be executed in each time: computing the velocity distribution for the next time step with the aid of a transition velocity distribution, which indicates how the objects associated with a grid cell in question move from one time step to the next, based on the preceding velocity distribution; for each grid cell, calculating a transitional probability information item, which indicates, for objects in each grid cell, probabilities of the objects in question reaching possible, further grid cells, as a function of the velocity distribution; calculating an occupancy probability for each grid cell for a subsequent time, based on the transitional probability information item; operating a system as a function of the occupancy probabilities for the grid cells. |
US11253990B1 |
Robot control
Methods, apparatus, and computer readable media applicable to balancing robots. Some implementations are directed to maintaining a given end effector pose (relative to a world frame) of an end effector of a balancing robot when there is a disturbance to a balancing base of the balancing robot. Some implementations are additionally or alternatively directed to transitioning a balancing robot from a fallen configuration to a balanced configuration. Some implementations are additionally or alternatively directed to mitigating the risk that a balancing robot will fall when interacting with actuable environmental objects (e.g., doors) and/or to lessen the disturbance to a balancing base when interacting with actuable environmental objects. |
US11253983B2 |
Torque screwdriver device
A torque screwdriver device is provided, including: a housing, including a barrel and a cover coveringly connected with the barrel; an input shaft portion, rotatably assembled with the barrel; an output shaft portion, rotatably assembled with the barrel and including a socket mechanism; a torque clutch mechanism, including a first engaging portion disposed on the input shaft portion and a second engaging portion disposed on the output shaft portion, an elastic preload member biasing one of the first and second engaging portions, and a first bearing mechanism, the first bearing mechanism including a stop member abutted against the housing, a support member and at least one low friction member disposed between the stop member and the support member, at least one of the stop member and the support member being movable relative to the at least one low friction member. |
US11253979B2 |
Adjustable single handle tool
Adjustable-size jaw sub-assemblies, jaw assemblies made from such sub-assemblies, and tools, particularly hand tools, made using such jaw assemblies. A plurality of jaws are connected to a base ring by pivot pins. Cam follower recess can be defined at positions of the inner perimeter of the base ring, and between opposing faces of the base ring. In the jaw assemblies, an actuator, such as a cover plate, covers at least a portion of one of opposing faces of the base ring, and one or more bridges connect the jaws to the actuator. Movement of the base ring relative to the actuator causes the jaws to pivot about the pivot pin axes, with the jaws moving in concert with each other thereby to reduce or expand the size of a work opening defined by the jaws. |
US11253973B2 |
Fluid pressure vise actuator
A fluid pressure vise actuator includes a housing and an inner bore of the housing. A piston is disposed in the housing, and the piston is configured to actuate based on a pressure increase in ports of the housing. A gear is also disposed in the inner bore of the housing, and a portion of the gear is adjacent to the piston such that an actuation of the piston is configured to rotate the gear. The gear includes a socket configured to interface with a vise and operate the vise based on a rotation of the gear. The housing also includes adjustable clamping blocks configured to engage with the vise to provide support for the housing during operation. An adjustment of the clamping blocks enables the fluid pressure vise actuator to interface with multiple types of existing vises. |
US11253970B2 |
Slurry cooling device and slurry supply system having the same
According to the present invention, there is provided a slurry supply system including: a slurry mixing unit configured to mix slurry; a slurry supply unit in which the slurry mixed in the slurry mixing unit is stored and configured to supply the slurry to a polishing apparatus; a pipe configured to connect the slurry mixing unit and the slurry supply unit; and a slurry cooling unit installed in at least one of pipes configured to connect the slurry supply unit and the polishing apparatus to cool down the mixed slurry. |
US11253969B2 |
Belt sander having fast-lift cover structure
A belt sander having a fast-lift cover structure includes a drive mechanism, a body and a cover. The drive mechanism includes a drive module, a tension arm, a sanding belt surrounding the drive module and the tension arm. The body receives the drive module. The body includes a base, an extendable support rod extended from the body and connected to the tension arm, and a cover fastening assembly disposed at the base. The cover fastening assembly includes a release and a resilient element for restoring the release to its original position. One end of a cover is pivotally connected at one side of the body, and the other end of the cover includes a fastening portion engaged with the release. Operation is easy, no hand tools are required, and the cover does not fall off. |
US11253966B2 |
Modular frame structure for machining center
A modular frame structure for a machining center which includes at least one modular unit having a first and a second individual module. Each individual module includes two mutually parallel vertical columns, each one extending parallel to a vertical direction; a pair of first horizontal cross-members, each one extending parallel to a first horizontal direction, each horizontal cross-member of the pair of first cross-members being joined to both columns.The modular unit further includes two pairs of second horizontal cross-members, each horizontal cross-member parallel to a second horizontal direction that is perpendicular to the first horizontal direction. |
US11253965B2 |
Supporting a workpiece on support slats of a workpiece support
Methods and devices for supporting a workpiece on support slats of a workpiece support during machining of the workpiece by thermal separation by a separation beam directed onto the workpiece are provided. In one aspect, a support slat includes support projections on a workpiece side extending in a longitudinal direction of the support slat. The support projections follow one after another in the longitudinal direction at a mutual distance to form projection gaps. On an underside of at least one support projection remote from the workpiece side, the support slat defines a recess covered by the support projection toward the workpiece side. The recess extends in a transverse direction of the support slat. The support projection covering the recess is separably connected to the rest of the support slat and is separable from the support slat with opening the recess toward the workpiece side. |
US11253963B1 |
Separable component assembly having reduced seal stiction
A separable component assembly is disclosed. The separable component assembly can include a first component having a first interface portion. The separable component assembly can also include a second component coupled to the first component. The second component can have a second interface portion. In addition, the separable component assembly can include a seal disposed between the first and second interface portions. The seal can have a first interface surface associated with the first interface portion. The seal can also have a second interface surface in contact with the second interface portion. Additionally, the seal can have a peel initiator defining a discontinuity in a portion of the second interface surface. Upon separation of the first and second components from one another, the discontinuity can create a stress concentration in the second interface surface that initiates peeling of the second interface surface away from the second interface portion. |
US11253952B2 |
Laser processing apparatus
A laser processing apparatus includes a light source configured to generate a laser beam, and a light converging optical system configured to converge laser beam to a focal point at an object to be processed, the light converging optical system including a through-hole optical element and a composite optical element under the through-hole optical element, wherein the through-hole optical element includes a first recess portion configured as a concave mirror at a lower surface of the through-hole optical element, and wherein an upper surface of the composite optical element is convex and includes a first region configured to reflect the laser beam and a second region configured to transmit the laser beam. |
US11253951B2 |
Method for the pretreatment of rare-earth magnets prior to soldering using nanocrystalline soldering foils and magnetic component
A magnetic component with a rare-earth magnet is provided. The rare-earth magnet has a bronze coating that partially or entirely covers the surface of the rare-earth magnet. Further, the tin coating partially or entirely covers the bronze coating. A production process for the magnetic component as well as a soldering method for connecting the magnetic component with a substrate is also provided. |
US11253949B2 |
Device and method for welding together two joining partners by means of friction stir welding, which prevents the joining partners being contaminated by the welding residue
The invention relates to a method and to a device for welding together two joining partners by means of friction stir welding, which prevents the joining partners being contaminated by welding residue. The method comprises the following features: a welding head that can be integrated into any machine, said welding head being in the form of a spindle drive driven by a drive unit, comprising a mounting flange for securing the device assisting the welding process, and a clamping system for receiving a frustoconical-shaped tool having a welding and smoothing shoe for guiding a welding pin (11), a device (17) integrated into the welding and smoothing shoe for grinding the waste produced during the welding process, the waste produced during welding is then removed by means of one inlet channels for fluid arranged in the upper and/or lower area of the frustoconical-shaped tool for the fluid (20, 18) and a suction channel (19). |
US11253947B2 |
Magnet wire bonding method and bonding structure
The present invention relates to a magnet wire bonding method and a bonding structure, and more particularly to a new improvement for ultrasonically bonding a longitudinal outer peripheral surface of a magnet wire having no entangling part to a flat surface of a flat part of a terminal pin. A magnet wire bonding method and structure, comprising: using a terminal pin (11) having a flat plate part (40) provided in a pin part (11a) as a terminal pin holding part (3); placing a magnet wire (13) in a longitudinally spread state on a flat surface (40a) of the flat plate part (40) without being entangled; and ultrasonically bonding an outer peripheral surface (13E) of the magnet wire (13) onto the flat surface (40a) with an ultrasonic horn (50). |
US11253945B2 |
Method for joining hot-stamped steel sheets
A method for manufacturing a hot-stamped steel sheet is provided. The method includes forming a welding portion of one steel sheet of a plurality of steel sheets to be joined. The welding portion has a thickness that is greater than that of a non-welding portion. The method also includes aligning welding portions of the plurality of steel sheets with each other, and joining the plurality of steel sheets by spot welding between the welding portions. |
US11253936B2 |
Reciprocating saw blade for a machine tool
A reciprocating saw blade for a machine tool, in particular a jigsaw blade, includes a first row of saw teeth and a second row of saw teeth. The first and second rows of saw teeth are arranged at an angle to a longitudinal axis of the reciprocating saw blade. The angle of the first row of saw teeth opposes the angle of the second row of saw teeth. The reciprocating saw blade also includes a further row of saw teeth arranged between the first and second rows of saw teeth. The further row of saw teeth is set back, in particular suddenly set back, towards the longitudinal axis in relation to the first and second rows of saw teeth. |
US11253932B2 |
Pipeline reinstatement tool
A new, innovative tool useful in fluidly coupling a lateral pipeline to a reinstated pipeline containing a continuous liner is provided. The pipeline reinstatement tool includes a flexible shaft that is coupled to a cutting head at a first end and a coupling assembly at a second end. The cutting head includes a hollow cylindrical member having cutting teeth that project longitudinally from the first end of the hollow cylindrical member. The tool includes a first compressible tensioner portion disposed about the flexible shaft proximate cutting head, a second compressible tensioner portion disposed about the flexible shaft proximate the coupling assembly, and a flexible sleeve portion disposed about the flexible shaft between the first compressible tensioner portion and the second compressible tensioner portion. |
US11253931B2 |
Coupling device
A device (1) for controlling operation of a chuck (2), the device (1) comprising a chuck (2) for centering a workpiece (3) to be machined; at least one electric motor (6) connected to at least one moveable clamping jaw (4), the at least one movable clamping jaw (4) being configured to be selectively moved by the at least one electric motor (6); a first inductive transmission device; a second inductive transmission device (8) disposed in alignment with the first inductive transmission device (7) such that measurement signals and/or electric power are inductively transmitted between the first transmission device (7) and the second transmission device (8); and an external control device (11) by means of which command and monitoring data required for the operation of the at least one clamping jaw (4), and for the operation and locking of the electric motors (6) can be entered and/or read. |
US11253927B2 |
Coated cutting tool
A coated cutting tool comprising a substrate and a coating layer formed on a surface of the substrate, wherein: the coating layer comprises a lower layer, an intermediate layer, and an upper layer in this order from the substrate side; the lower layer comprises one or two or more Ti compound layers containing a Ti compound of Ti and an element of at least one kind selected from the group consisting of C, N, O and B, the intermediate layer comprises an α-Al2O3 layer containing α-Al2O3, and the upper layer comprises a TiCNO layer containing TiCNO; an average thickness of the coating layer is 5.0 μm or more and 30.0 μm or less; in a specific first cross section, a misorientation A satisfies a specific condition; and in a specific second cross section, a misorientation B satisfies a specific condition. |
US11253926B2 |
Coated tool and cutting tool
A coated tool may include a base member including a first surface, and a coating layer located at least on the first surface of the base member. The coating layer may include a first layer and a second layer. The first layer may be located on the first surface and may include a titanium compound. The second layer may be contactedly located on the first layer and may include aluminum oxide. The coating layer may include a plurality of voids located side by side in the first layer in a direction along a boundary between the first layer and the second layer in a cross section orthogonal to the first surface. |
US11253925B2 |
Diamond tool piece
A high-pressure high-temperature, HPHT, diamond tool piece and a method of producing an HPHT diamond tool piece. At least a portion of the HPHT diamond tool piece comprises an aggregated nitrogen centre to C-nitrogen centre ratio of greater than 30%. The method includes irradiating an HPHT diamond material to introduce vacancies in the diamond crystal lattice, annealing the HPHT diamond material such that at least a portion of the HPHT diamond material comprises an aggregated nitrogen centre to C-nitrogen centre ratio of greater than 30%, and processing the HPHT diamond material to form an HPHT diamond tool piece. |
US11253924B2 |
Control device for machine tool and machine tool
A control device for a machine tool and a machine tool, for which settings of the number of vibrations per rotation become easy, is provided. The control device of the machine tool controls a relative rotation between a workpiece and a cutting tool and a relative reciprocal movement between the workpiece and the cutting tool in a feed direction to perform vibration cutting to the workpiece. The control device includes a control section for controlling a spindle headstock, a first tool post, and a second tool post, the workpiece W being installed on the spindle headstock, the first tool post being provided to be reciprocally movable along the feed direction with respect to the spindle headstock and installed with a first cutting tool for cutting the workpiece, and the second tool post being provided to be reciprocally movable along the feed direction with respect to the spindle headstock independently of the first tool post and installed with a second cutting tool for cutting the workpiece. |
US11253922B2 |
Method for real-time simultaneous and calibrated additive and subtractive manufacturing
A method for large-scale, real-time simultaneous additive and subtractive manufacturing is described. The apparatus used in the method includes a build unit and a machining mechanism that are attached to a positioning mechanism, a rotating platform, and a rotary encoder attached to the rotating platform. The method involves rotating the build platform; determining the rotational speed; growing the object and the build wall through repetitive cycles of moving the build unit(s) over and substantially parallel to multiple build areas within the build platform to deposit a layer of powder at each build area, leveling the powder, and irradiating the powder to form a fused additive layer at each build area; machining the object being manufactured; and cutting and removing the build wall. The irradiation parameters are calibrated based on the determined rotational speed. |
US11253921B2 |
Copper fine particle, method for producing same, and sintered body
An object of the present invention to provide copper fine particles which can be sintered at a lower temperature than that of the conventional copper fine particles without causing a cost increase, a decrease in productivity, a method for producing the copper fine particles, and a sintered body, and the present invention provides copper fine particles having a coating film containing cuprous oxide and copper carbonate on the surface thereof. |
US11253920B2 |
Method for preparation of copper nanocubes utilizing tributylphosphine as a ligand
A method for preparing copper nanocubes with specific facets and uniform size, the method comprising combining a copper complex solution in a reaction mixture with a ligand. Using a ligand of pure, unoxidized tributylphosphine, uniform copper nanocubes with six facets are prepared. |
US11253916B2 |
Method of production using melting and hot isostatic pressing
A method is provided for producing a three-dimensional object that includes an external skin, a 3D mesh enclosed in the skin and having a portion that penetrates at least a part of a thickness of the skin, and an unmelted portion enclosed in the skin. The object is formed from superposed layers each including an outer edge and an inner mesh, with the superposed outer edges forming the skin, and with the superposed inner meshes forming the 3D mesh. Each superposed layer is formed by scanning a powder layer using an energy beam to form micro-connections between grains of the powder without melting the metal powder. First and second melting and solidifying steps are performed using the energy beam to form the outer edge in one of the first and second steps and the inner mesh in the other of the first and second steps. |
US11253915B2 |
Vibrational densification of powder supply in additive manufacturing
Disclosed are an apparatus and method for densifying or compacting powder material in the supply bin of an additive manufacture machine to improve the quality of the object being made. For example, a removable or portable apparatus can be applied to the surface of the supply bin once the bin has been filled. The apparatus can include a vibrational component that agitates the underlying powder to compact the material. The apparatus can then be removed during the remainder of the additive manufacturing process, which then follows in its normal course. A vacuum can also be used the remove of air or other gases that are emitted during the compaction process, for example, as voids are filled during densification. |
US11253908B2 |
Ultrasonic rivet joining of dissimilar materials
A method for joining dissimilar materials is provided. The method includes a solid-state joining process in which a rivet is plunged into a predrilled hole in a top workpiece. When the rivet contacts the bottom workpiece, ultrasonic vibration by oscillatory motion of a sonotrode, such as horizontal, vertical, or rotational motion, creates frictional heat at the interface between the rivet and the lower workpiece. With the aid of frictional heat and axial compression, metallurgical bonding is achieved at the interface between the rivet and the bottom sheet, while being below the melting temperature of the bottom workpiece. The sonotrode is retracted while the rivet remains. |
US11253903B2 |
Centering method of rotary caulking device, rotary caulking device manufacturing method, hub unit bearing manufacturing method, vehicle manufacturing method, centering device of rotary caulking device, and rotary caulking system
In a preparation step, a frame (10), a concave spherical seat (15), a convex spherical seat (13), a rotation body (16), a rotating shaft (12), and a work holder (17) are assembled, a laser head (33) is attached to the convex spherical seat (13), and a light receiving unit (38) is attached to the work holder (17). In a rotation body centering step, an irradiation position of a laser beam (LB) with respect to a laser irradiation surface (41) is changed by rotating the rotation body (16) while allowing the laser irradiation surface (41) to be irradiated with the laser beam (LB) emitted from the laser head (33) and a trajectory of the irradiation position is checked. |
US11253899B2 |
Production of reinforced double-layer parts
A method for fabricating a double layer cup-shaped part may include shaping a first material into a hollow cylinder, mounting the hollow cylinder on a draw punch, where the draw punch may include an upper punch portion with a first diameter and a lower punch portion with a second smaller diameter. Mounting the hollow cylinder on the draw punch may include tightly fitting the hollow cylinder around the lower punch portion. The method may further include forming the double layer cup-shaped part by drawing a blank material through a draw die by placing the blank material over an upper opening of the draw die, and pressing the draw punch over the blank material. The first material may form an inner layer of the double layer cup-shaped part and the blank material may form an outer cup-shaped layer of the double layer cup-shaped part. |
US11253898B2 |
Hot-forming presses and methods of hot-forming workpieces
A hot-forming press (100) comprises a lower press assembly (102) and an upper press assembly (108). The lower press assembly (102) is movable along a vertical axis and comprises a lower die (106), and a lower hot-box portion (104), configured to receive the lower die (106). The upper press assembly (108) is movable along the vertical axis above the lower press assembly (102) and comprises an upper die (112), and an upper hot-box portion (110). The upper hot-box portion (110) is configured to receive the upper die (112) so that the upper die (112) is positioned opposite the lower die (106). The lower die (106) and the upper die (112) are configured to apply a forming pressure to a workpiece (114) that is received between the lower die (106) and the upper die (112). The lower hot-box portion (104) and the upper hot-box portion (110) are configured to heat the workpiece (114). |
US11253897B2 |
Method and device for manufacturing plate parts for a heat exchanger
The present invention relates to a method and a device for manufacturing plate part blanks for a heat exchanger. A sheet material (2) in the form of continuous sheeting is worked between two rolls (5, 6) with opposite surface patterns (7, 7′, 8) to form profiled plate part blanks (3, 3′,3″) into the sheet material (2) so that the rolls (5, 6) are synchronized to rotate at substantially same rate by controlling the rotation of them in relation to each other with common synchronization gear (9), which gear is coupled to the rolls (5, 6) by means of shafts (10, 11) with disk pack or gear couplings. |
US11253894B1 |
Waste destruction device
A device for converting harmful waste products into environmentally friendly discharge is provided. The discharge, as a result of the waste destruction process, meets or exceeds the Environmental Protection Agency (EPA) standards. The device includes a waste disposal chamber where a crucible is positioned. The crucible is configured to retain a removable basket that is heated via induction heating. The waste residing within the removable basket is then vaporized and ionized within a vacuum to form a waste gas that is drawn through an accelerated jet of thermal plasma via vacuum suction. Once the waste gas passes through the plasma, it passes through a discharge duct where it is condensed by a heat exchanger and exhausted into the environment surrounding the device. |
US11253893B2 |
Suction unit for a robotic sorter
An item sorting system (1) includes a moving belt (1a) and one or more sorting units (2). The sorting unit (2) has an enclosure (3) with a work aperture (4), a suction unit (5) with a suction head (6), and a robot arm unit (7) mounted in the enclosure (3) for moving the suction head (6) within a predetermined operating space within the enclosure (3). The enclosure (3) has one or more shell sections (3a) forming a side wall (3b) of the enclosure (3). In a further aspect, the suction unit (5) has a suction head (6) connected to a suction head channel (11), a low pressure source (12a) connected to the suction head channel (11) via a first valve (13), and a control unit (15) connected to the first valve (13) and arranged to actuate the first valve (13) between a suction position and a release position. |
US11253885B2 |
Aseptic aerosol misting device
A handheld misting device includes a sonic generator, a power source coupled to the sonic generator, at least one reservoir containing a first liquid, and a conduit from the at least one reservoir. The sonic generator includes a converter and an elongate horn comprising a first horn section coupled to the converter and a second horn section physically connected to and removable from the first horn section. Sonic energy delivered to the first horn section is conducted to the second horn section. The conduit transports liquid from the at least one reservoir to the second horn section to a delivery opening distal the first horn section. |
US11253884B2 |
Device for cleaning and drying a spraying unit
A device for cleaning and drying a spraying unit, the device containing: a top end and a bottom end; the top and bottom end connected to each other by a housing; the housing having an opening proximate the top end, for receiving at least a portion of a spraying unit; a first liner within the housing; a second liner within the first liner; the first liner fitting within the housing forming a space between an outside wall of the first liner and an inside wall of the housing; the second liner fitting within the first liner forming a space between an outside wall of the second liner and an inside wall of the first liner; the opening further containing an open cap, proximate the top end; the device having at least one vacuum air supply influent port, at least one drying air supply influent port and at least one solvent supply influent port. |
US11253881B2 |
Pump assembly of non-metal pump type cosmetic container
A non-metal pump type cosmetic container according to an embodiment of the present invention may efficiently process recycling after use. Also, Due to an operation of the elastic pump that is more flexible than a rigid metal spring, pumping may be achieved and thus a cosmetic material may be sensitively discharged even by a small force, leading to increases in tactile sensitivity and operational sensitivity. In addition, the structure of the elastic pump formed of resin having a relatively good deformation property is improved such that the elastic pump delicately may descend without being distorted during deformation, contributing to an improvement in product reliability according to a precise operation of each component. |
US11253877B2 |
Oil distribution assembly
The present disclosure concerns an oil distribution assembly for a system having rotating components requiring a supply of oil, such as bearing components of a gas turbine engine. Example embodiments include an oil distribution assembly for a gas turbine engine, comprising: an oil distributor mounted for rotation about a rotation axis of the assembly and comprising an internal volume having a plurality of channels extending along an inner radial surface of the oil distributor; and an oil injector arranged to direct a supply of oil to the plurality of channels in a direction having a component in a first direction along the rotation axis; wherein each of the plurality of channels is angled relative to the rotation axis such that a radial distance between each channel and the rotation axis increases along the rotation axis. |
US11253875B2 |
Multi-dimple orifice disc for a fluid injector, and methods for constructing and utilizing same
A fluid injector for injecting fluid is disclosed, including a body; a fluid passageway defined in the body and extending from an inlet to an outlet of the fluid injector; a valve seat disposed internally of the body and forming part of the passageway; a valve element that is selectively reciprocated relative to the valve seat to close and open the passageway to fluid flow by seating and unseating the valve element on and from the valve seat, respectively; and an orifice disc disposed in the passageway downstream of the valve seat in a direction of the fluid flow through the fluid injector, the orifice disc including a plurality of dimples and a plurality of orifices defined through the orifice disc, each dimple including at least one orifice located thereon and each dimple having an asymmetrical cross-section. |
US11253871B2 |
Electrostatic precipitator integrated with double-skin facade of building
An electrostatic precipitator integrated with a double-skin facade of a building, includes: an outer window installed at an outdoor side of the building; an outer upper opening and an outer lower opening installed at upper and lower portions, respectively, of the outer window for indoor ventilation; an inner window providing a hollow layer between the inner window and the outer window by being installed at a room side facing the outer window; an inner upper opening and an inner lower opening installed at upper and lower portions, respectively, of the inner window for ventilation; at least one discharge electrode charging particles introduced into the hollow layer through the outer lower opening by being installed in the hollow layer; and dust collecting electrodes precipitating charged particles by being installed in contact with the hollow layer. |
US11253870B2 |
Magnetic baffle insert for use with a basket strainer
A basket strainer insert having a body with one or more magnets disposed therein. The basket strainer insert includes a baffle that is removable. The movement of withdrawing the baffle from the body allows magnetic debris to be removed. A baffle may be disposed at the center of the elongate intermediate portion of the body. The baffle may comprise a collar and two or more symmetrical lobes, each lobe comprising an upper portion and a lower portion. Alternatively, the baffle may be a hollow shape with a plurality of apertures. |
US11253869B2 |
Magneto-centrifugal flotation cell for concentrating materials which reduces water consumption and method of use
The invention relates to a magneto-centrifugal flotation cell for ore concentration which reduces water consumption. A disadvantage of conventional flotation cells is the use of a large amount of water, some flotation cells requiring at least 60% water. The present invention uses ore pulp with increased density and viscosity, owing to the application of an axial magnetic field, wherein the Lorentz force, which is the force exerted by an electromagnetic field that receives a charged particle or an electrical current, can be used. The solution is a cell which, in addition to the forces that usually act on conventional flotation cells, uses external forces which, in principle, produce synergy in the separation of ore particles that have different gravitational and magnetic properties. |
US11253868B2 |
Gold panning machine
An apparatus and method for separating heavy metals and precious stones from alluvial material wherein the apparatus comprises a frame, a gold pan supported on the frame and a vibration means supported on the frame adapted to provide a vibration to the gold pan. The apparatus may further comprise a water pump supported on the frame operable to introduce a quantity of water to the gold pan. The apparatus may further comprise a screen supported above the gold pan. The method comprises providing a gold pan supported on a frame, introducing a quantity of an alluvial material to the gold pan and vibrating the gold pan so as to remove lighter material leaving the heavy metals and precious stones therein. |
US11253865B2 |
Comminuting device
An exemplary aspect encompasses a comminution apparatus for comminution of material to be comminuted which includes a machine frame, a driven comminution roller which is mounted on the machine frame and comminution tools. A comb including counter tools and a comb flap is pivotably mounted on the machine frame, wherein the comminution roller cooperates with the comb for comminution, wherein the comb is pivotably mounted on the comb flap in the range of its upper end, wherein at least one spring means engages the comb with its first end and wherein the comb is resiliently supported via the spring means. In accordance with one aspect the spring means is supported by its second end on the machine frame. |
US11253860B2 |
Digital microfluidic devices and methods
Digital microfluidic (DMF) apparatuses, systems, devices and associated fluid manipulation and extraction devices, and methods of using them are presented. The devices may be useful for analysis of clinical, laboratory, chemical, or biological samples. A fluid application and extraction interface device may include a waste reservoir with a fluid trap and a transfer conduit extending through the waste reservoir so that fluid may pass from the transfer conduit into the waste reservoir and be trapped within the waste chamber. A transfer conduit may be configured to double back on itself and to hold a fluid sample. A DMF apparatus may be configured to hold and process large sample volumes. |
US11253855B2 |
Arrangement in a capillary driven microfluidic system for dissolving a reagent in a fluid
There is provided an arrangement in a capillary driven microfluidic system for dissolving a reagent in a fluid. The arrangement (200) comprises a channel (102) for receiving a fluid at a first end, a valve (105) arranged at a second end of the channel so as to control a flow of the fluid to stop as it reaches the second end of the channel, and an actuator (108) for opening the valve (105) a predetermined time after receipt of the fluid by the channel (102). The arrangement further comprises one or more structures (106) for holding a dried reagent. The one or more structures (106) each has a width (W2) which is larger than a width (W1) of the channel (102), and the one or more structures are coupled to a side wall of the channel such that the fluid is allowed to enter the one or more structures from the channel, dissolve the dried reagent held therein, and diffuse back into the channel. |
US11253853B2 |
Fluidic systems comprising an incubation channel, including fluidic systems formed by molding
Fluidic devices and methods are provided. |
US11253846B2 |
Metal complexes for depositing films and method of making and using the same
Provided herein are methods of catalytic hydrosilylation, including triggerable methods, using metal-ligand complexes as catalysts, characterized by formula MLxDy; wherein: M is a metal; x is equal to the oxidation state of M; each D is independently a neutral coordinating ligand; y is zero or an integer selected from the range of 1 to 4; and each L is independently a mono-anionic ligand. L may be a η1,η2-β,β-disubstituted-ω-alkenyl ligand. |
US11253845B2 |
Activation of inert metal components to catalysts
Processes for transforming an inert metal component into an active metal catalyst are provided. Apparatus and methods using active metal catalyst prepared according the process described herein are also provided. |
US11253844B2 |
Oligomerization catalyst and process for the production thereof
The invention relates to an oligomerization catalyst comprising nickel oxide and silica-alumina support material and to a process for oligomerization of C3- to C6-olefins using the oligomerization catalyst. |
US11253841B2 |
Copper aluminium oxide catalyst for preparing furfuryl alcohol from furfural and a preparation of said catalyst
The present invention relates to a copper aluminium oxide catalyst for preparing a furfuryl alcohol from a furfural, comprising a copper-alumina spinel structure and having surface area in the range from 0.5 to 5 m2/g; wherein said catalyst is prepared from a process comprising the following steps: (i) dissolving copper salt and aluminium salt in a solvent; (ii) adding organic acid into mixture obtained from step (i); (iii) heating mixture obtained from step (ii) at the temperature higher than 150° C. until said mixture is combusted into solid; and (iv) calcining the solid obtained from step (iii) at the temperature in the range from 700 to 1,000° C. The catalyst according to the invention gives a high conversion of furfural to furfuryl alcohol and high furfuryl alcohol yield. |
US11253839B2 |
Shaped porous carbon products
Shaped porous carbon products and processes for preparing these products are provided. The shaped porous carbon products can be used, for example, as catalyst supports and adsorbents. Catalyst compositions including these shaped porous carbon products, processes of preparing the catalyst compositions, and various processes of using the shaped porous carbon products and catalyst compositions are also provided. |
US11253831B2 |
Catalytically heated fuel processor with replaceable structured supports bearing catalyst for fuel cell
A highly compact heat integrated fuel processor, which can be used for the production of hydrogen from a fuel source, suitable to feed a fuel cell, is described. The fuel processor assembly comprises a catalytic reforming zone (29) and a catalytic combustion zone (28), separated by a wall (27). Catalyst able to induce the reforming reactions is placed in the reforming zone and catalyst able to induce the combustion reaction is placed in the combustion zone, both in the form of coating on a suitable structured substrate, in the form of a metal monolith. Fe—Cr—Al—Y steel foils, in corrugated form so as to enhance the available area for reaction, can be used as suitable substrates. The reforming and the combustion zones can be either in rectangular shape, forming a stack with alternating combustion/reforming zones or in cylindrical shape forming annular sections with alternating combustion/reforming zones, in close contact to each other. The close placement of the combustion and reforming catalyst facilitate efficient heat transfer through the wall which separates the reforming and combustion chambers. |
US11253829B2 |
Process for producing solid particles
Process for the production of solid particles comprising a material with melting point from −20 to 300° C. at atmospheric pressure, characterized in that a mixture comprising: a1) the material in molten form and a2) the material in solid form is mixed by means of an extruder to give a paste, this is forced through a pelletizing die to give strands, and the strands are comminuted. |
US11253825B2 |
Mixing paddle
A mixing paddle is comprised of a compound, integral center shaft, a rim, a first plurality of parallel blades and a second plurality of parallel blades. The compound, integral center shaft bisects the rim, creating a first side of the rim and a second side of the rim. The first plurality of parallel blades is disposed between the compound, integral center shaft and the first side of the rim. The second plurality of parallel blades is disposed between the compound, integral center shaft and the second side of the rim. The first plurality of parallel blades is orthogonal to the second plurality of parallel blades. |
US11253820B2 |
Lithium extraction composite for recovery of lithium from brines, and process of using said composition
A lithium extraction composite comprising: (i) a porous support and (ii) particles of a lithium-selective sorbent material coated on at least one surface of the support, wherein the support has a planar membrane, fiber (or rod), or tubular shape. A method for extracting and recovering a lithium salt from an aqueous solution by use of the above-described composition is also described, the method comprising (a) flowing the aqueous source solution through a first zone or over a first surface of the lithium extraction composite to result in selective lithium intercalation in the lithium-selective sorbent material in the first zone or first surface; and (b) simultaneously recovering lithium salt extracted in step (a) from said lithium-selective sorbent material by flowing an aqueous stripping solution through a second zone or over a second surface of the lithium extraction composite in which lithium ions from the first zone or first surface diffuse. |
US11253819B2 |
Production of thin film composite hollow fiber membranes
System, devices, and method for the production of thin film composite hollow fiber membranes on a hollow fiber support structure. The system includes a comb and roller device, or comb and dual roller device, which can be used to define a submerged travel path in a first solution bath for a hollow fiber. The combs and rollers control the amount of time the hollow fiber spends in the first solution. The first solution contains a first monomer, and the hollow fiber is impregnated with the first monomer. The amount of impregnation depends on the time spent in the first solution. Subsequent immersion in a second solution containing a second monomer results in the formation of a thin film composite hollow fiber membrane. |
US11253818B2 |
Method for producing cellulase and apparatus for said method
A method of producing cellulase includes steps (1) to (3): (1) subjecting an aqueous solution of cellulase derived from filamentous fungi to filtration through an ultrafiltration membrane with a molecular weight cut off of 100,000 to 200,000 to obtain a filtrate and concurrently obtain a concentrated enzyme liquid as a retentate; (2) further subjecting the filtrate obtained in step (1) to filtration through a second ultrafiltration membrane with a molecular weight cut off of 5,000 to 50,000 to obtain a second concentrated enzyme liquid as a retentate; and (3) mixing the concentrated enzyme liquid obtained in steps (1) and (2) to obtain cellulase derived from filamentous fungi. |
US11253811B2 |
Process for reducing energy consumption in the regeneration of hybrid solvents
Disclosed is a process for regenerating a hybrid solvent used to remove contaminants from a fluid stream and to provide an improved yield of purified fluid. Said process comprises at least one purification unit (12) and at least one regeneration unit (40) wherein condensed water 62 from the regeneration unit is recycled back into the purification unit and none of the condensed water is reintroduced into the regeneration unit. |
US11253810B2 |
Adsorbent for hydrocarbon recovery
Disclosed in certain embodiments are sorbents for capturing heavy hydrocarbons via thermal swing adsorption processes. |
US11253807B2 |
Channel-framed, pleated air filter with bridging filaments
A rigid, channel-framed, non-compressible, non-nestable, pleated air filter, comprising: a tightly-pleated air filter media comprised of a nonwoven fibrous web and with an upstream face and a downstream face, wherein the tightly-pleated air filter media comprises a plurality of upstream (and downstream) pleat tips and upstream (and downstream) pleat valleys, the tightly-pleated air filter media comprising a plurality of upstream (and downstream) linear bridging filaments that are at least substantially parallel to each other and are oriented at least substantially orthogonal to the pleat direction and are extrusion-bonded to at least some of the upstream (and downstream) pleat tips, and, a channel frame comprising four major frame portions, with each major frame portion being mounted on one of the four major edges of the pleated air filter media. |
US11253804B2 |
Apparatus and method to clean particle loaded fluid using low energy multi-flow splitter technology requiring no filter media
The present invention relates to an apparatus and a method of cleaning particle loaded “dirty” air using a multi flow-splitter technology in combination with at least one cyclone system which requires minimal energy to operate due to low pressure drops used to generate the fluid flows whilst allowing to exert high centrifugal or G-Force on the infeed fluid stream. This further allows to operate the particle removal process such that conventional additional filter media become optional, such that the technology may operate a significantly reduced or even without the need for maintenance and/or repair. Low internal air turbulence ensures a very high separation efficiency. Optionally adding additional explosion safe low-energy down-stream filtration stages with variable speed system fan provides optimal operational performance and operational flexibility. |
US11253803B2 |
Dust collector and electronic system capable of automatically removing dust
A dust collector includes a housing, a passage structure and a dust collecting region. The passage structure is disposed in the housing, and configured to accelerate an airflow containing dust particles and separate the dust particles from the airflow. The dust collecting region is connected to the passage structure, and is configured to collect at least part of the dust particles of the airflow. |
US11253799B2 |
Enclosed media fluid filtration device
A filtration device comprising a media basket, a baseplate, and a canister. The media basket is affixed to the baseplate. The canister has a cavity therein and is detachably coupled with the baseplate to enclose the media basket. The media basket contains a porous filtration material that efficiently removes contaminants from liquid. The device is configured to establish a first siphon to convey liquid from outside the device into the canister cavity through a canister pipe when a liquid level outside the filtration device is higher than the top of the weir in the canister pipe and configured to establish a second siphon to convey liquid from canister cavity through the top of a center riser pipe and out an outlet pipe when the first siphon has been established and the liquid level outside the filtration device is higher than the top of the center riser pipe. |
US11253798B2 |
Nutrient removal filtration system and method
Systems, devices, and methods for providing nutrient removals in an up flow filtration storm water system for treating water to very high clean levels using filtration media. A filtration media can be supported by a screen above a floor in a vault allows for incoming storm water to pass into a void space above the floor into the screen and filtration media and then out an outlet to the vault. The filtration media can include recyclable and/or natural particles. Layers of river rocks can be placed on top of and below the filtration media. The captured debris can drop to the floor. The long lasting filtration media can be cleaned by being backwashed. |
US11253793B1 |
Isolating components from plants
The invention relates to methods of separating or isolating a component from a plant using freeze separation. The invention includes products produced by said methods. |
US11253790B2 |
Numerical operation system
A numerical operation system for a plurality of individuals includes a contactless communication tag each included in a plurality of individuals, a reader allowed to read the contactless communication tag, and a control unit to which a result read by the reader is input, wherein the control unit is configured such as to acquire, from the result read by the reader, at least numerical values each corresponding to the plurality of individuals and operator symbols for operating the numerical values to calculate a total value based on the numerical values and the operator symbols. |
US11253783B2 |
Method for training AI bot in computer game
The invention discloses a pure end-to-end deep reinforcement learning for training car racing game AI bot that uses only the velocity information extracted from screen for both training and testing phases without using any internal state from game environment, such as the car facing angle. The learned AI bot can play better than the average performance of human players. In addition, the reward function is designed to consist only the velocity value, and use Ape-X distributed training framework combined with a variant of Deep Q Network to solve the sparse training signal problem caused by the reward function of an original design. Moreover, limit learner rate method is designed that improves the training efficiency and training performance. The AI bot trained in this way can achieve performance beyond the average human level and reach a level close to professional players. |
US11253781B2 |
Player biofeedback for dynamically controlling a video game state
Various embodiments are directed towards employing one or more physical sensors arranged on or in proximity to a video game player to obtain biofeedback measures that are then useable to dynamically modify a state of play of a video game. The sensors may be connected or even unconnected to the game player, replace, or otherwise augment traditional physical game controllers. The sensors gather various biofeedback measures and provide such measures to a biofeedback application programming interface (API). Before and/or during video game play, the video game queries the biofeedback API to request inferences about the game player's state of arousal. The response to the query is then used to modify the state of the video game play. Where the video game is a multi-player video game, biofeedback measures from other game players may also be obtained and used to further modify the state of the video game play. |
US11253775B2 |
Game tile shuffler
A game tile shuffler may include a tile loader, a tile container, a belt, and a tile dispenser. The tile loader may be capable of holding a plurality of game tiles. The game tiles pass from the tile loader to the tile dispenser through the tile loader and the belt. The belt may be capable of capturing and carrying the game tiles. The tile dispenser may include a chute opening and a tunnel that may split into multiple directions. A tunnel door may direct the game tiles between the multiple directions. The tile dispenser may be capable of identifying individual game tiles prior to dispensing. The game tile shuffler may be operable between a shuffle mode, whereby game tiles are circulated through the device, and a dispensing mode, whereby game tiles pass through the tunnel. |
US11253763B2 |
Baseball hitting apparatus
An apparatus for assisting and improving baseball hitting is described. The apparatus includes a spherical object having an interior anchor and a cord extending therefrom. An adjustable mass body is disposed within the spherical object along the cord. The interior anchor allows the spherical object to rotate about the cord. |
US11253761B2 |
Ergonomic knob insert for hollow stick
Described is a knob for application to the gripping end of a hollow stick. The knob comprises a rounded, oblique, cylindrical support structure, transitional shaft and tang aligned on a common longitudinal central axis. The support structure comprises a greater diameter rounded, cantle-like support and gripping structures. |
US11253760B2 |
Removable and reattachable golf club grip
Attachment of an interchangeable grip sleeve particularly suited for golf requires three basic securing movements. In the first movement, the grip is situated and secured into place on the shaft by fastening toe components at the lower, distal portion of the grip onto the shaft using an insertion tool. In the second movement, heel components of the grip are positioned onto the shaft, by either rotational torque or downward pressure, optionally using a tightening tool, which results in securing the upper, proximal portion of the grip onto the shaft. In the third movement, once both heel and toe embodiments of the grip have been fastened to the shaft, the internal core diameter of the grip is decreased in order to secure the grip to the shaft, such as by rotating or twisting the entire grip body, wherein an internal mechanism maintains the grip body in the torqued or twisted position, thereby preventing the grip body from rotating back. |
US11253746B2 |
Exercise bar and grip handle
Handle grip are configured to interface to the end of a bar allowing a user to employ the bar for motion, exercise, stretching or other activity. For example, the handle grips may slip onto the bar under force. The handle grips include a grip section, configured to provide a surface the user can grab. Accordingly, the grip surface may include features that increase the effective friction coefficient. The handle grip also includes an end section configured to react both axial and lateral loads applied by the user via the grip section. The bar can be sectioned, making storage and transport easier. Accordingly, the sectioned bar can be assembly to provide the desired length of exercise bar. |
US11253740B2 |
Linear bearings and alignment method for weight lifting apparatus
A weight system having at least one weight stack moveable in a vertical direction on a lift rod, and a bearing block for housing a linear bearing. The invention further includes a method and apparatus for aligning the linear bearing. |
US11253736B2 |
Dispatching UAVs for wildfire surveillance
A dispatch system includes an unmanned aerial vehicle (UAV) interface for interfacing with one or more UAVs for wildfire detection. The UAV interface transmits an instruction for a UAV to navigate to a location of a potential wildfire, and receives data captured by at least one sensor of the UAV. The dispatch system further includes a fire detection engine to process the received data to identify the presence of a wildfire, and a web server to provide a user interface that includes an alert regarding the wildfire. The alert may include the location of the wildfire. |
US11253735B1 |
System and method for safe sipper mask
A system and method for safe sipper mask with a slidable element to open and close an opening on the mask as well as straw placed in the opening with a protrusion to stop the straw from entering too far into the mouth of the wearer whereby the mask has a stabilizer positioned between the inner and outer surfaces to provide stiffness. |
US11253727B2 |
Magnetic resonance visible markers for magnetic resonance imaging guided brachytherapy
Magnetic resonance (“MR”) visible markers for use in MR-guided placement of brachytherapy seeds, and for use in other MR-guided interventional procedures, are described. The MR-visible markers generally include a tube in which an absorbent thread assembly is disposed. The tube is made fluid-tight by sealing it at both ends with suitable end plugs. The absorbent thread assembly is soaked in a suitable MR-visible fluid. |
US11253725B2 |
Time optimized radiation treatment
In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area. |
US11253724B2 |
Method for treating cancerous and pre-cancerous skin
The present disclosure provides a method for treating clinical or pre-clinical skin damage in a skin field of a subject, wherein the skin field has been allocated a skin cancerization field index (SCFI) score of at least 1 as determined by a process comprising the steps of: (i) assessing the number of keratoses in the skin field; (ii) assessing the thickness of the thickest keratosis in the skin field; and (iii) assessing the proportion of the field affected by clinical or subclinical skin damage. Based on the assessments made in (i), (ii) and (iii) the subject is optionally treated by at least one of (a) freezing one or more lesions, (b) shaving, curetting or surgically removing one or more lesions, (c) applying a topical treatment for actinic keratosis, basal cell carcinoma or squamous cell carcinoma, and (d) radiation therapy. |
US11253719B2 |
Photobiomodulation therapy systems and methods
Photobiomodulation therapy systems provide a highly effective way to treat many common ailments to the human body. Many embodiments described herein enable two or more light therapy devices to be communicatively coupled together in various ways. In some embodiments, the light therapy system includes a first light device and a second light device arranged and configured to be communicatively coupled to the first light device. Each of the light devices may include a housing, a communication module, and a plurality of lights arranged and configured to emit at least one of red light and near infrared light. |
US11253715B2 |
Wearable medical device with disposable and reusable components
Embodiments of a wearable device are provided. The wearable device comprises a reusable component and a disposable component. The disposable component comprises a patient engagement substrate comprising adhesive on a bottom side, an electrode on the bottom side, a disposable component electrical connector, and a disposable component mechanical connector. The reusable component comprises a plurality of sealed housings mechanically coupled to each other and movable with respect to each other, each of the plurality of housings containing one or more of a capacitor and a controller, a reusable component mechanical connector adapted to removably connect to the disposable component mechanical connector, and a reusable component electrical connector adapted to removably connect to the disposable component electrical connector. The device can comprise a cardiopulmonary physiologic monitor or an automatic external defibrillator, among other types of devices. |
US11253713B2 |
Incorporation of the electrodes for defibrillation into the patient-facing components of automated cardiopulmonary resuscitation systems
An automated resuscitation system is provided, which can improve the outcome of patients suffering ventricular fibrillation or the ventricular tachycardia variants of cardiac arrest. This outcome can be achieved by a device that integrates automatic mechanical or pneumatic capability with electrical countershock capability such that the probability of defibrillation or cardioversion with return of spontaneous circulation is increased. |
US11253711B2 |
Implantable energy storage device including a connection post to connect multiple electrodes
An example includes a capacitor case sealed to retain electrolyte, at least one anode disposed in the capacitor case, the at least one anode comprising a sintered portion disposed on a substrate, an anode conductor coupled to the substrate in electrical communication with the sintered portion, the anode conductor sealingly extending through the capacitor case to an anode terminal disposed on the exterior of the capacitor case with the anode terminal in electrical communication with the sintered portion, a second electrode disposed in the capacitor case, a separator disposed between the second electrode and the anode and a second electrode terminal disposed on an exterior of the capacitor case and in electrical communication with the second electrode, with the anode terminal and the second electrode terminal electrically isolated from one another. |
US11253709B2 |
Electrode lead with continuously variable fixation length
An electrode lead for the coronary sinus, with a lead body that has a distal section for insertion into the coronary sinus, and at least one electrode to make contact with body tissue, the at least one electrode being arranged on the distal section of the lead body. The electrode lead has a fixation device that can be extended out of the lead body to fix the electrode lead in a blood vessel. |
US11253704B2 |
Devices and methods for treating tinnitus using electrical stimulation
Electrical stimulation devices can be used to treat tinnitus. For example, tinnitus can be treated using implantable electrodes and stimulation devices for delivering electrical stimulation to a patient's cochlear region. Cochlear surface electrode(s), endosteal electrode(s), subendosteal electrode(s), intraosseous electrode(s), or short intracochlear electrode(s) (or a combination thereof), connected to existing or modified cochlear implant receiver/stimulator technology, can provide a successful model for long-term treatment of tinnitus in a large number of patients. In some cases, patients can simply turn on the tinnitus implant when experiencing troublesome tinnitus and gain instant relief. |
US11253699B1 |
Cardiac pacing lead
A medical lead includes a lead body, a connector pin proximate to a proximal end of the lead body, a helix extending from a distal end of the lead body, an electrode proximate to the distal end of the lead body, and a cable conductor within the lead body and including an electrode proximate a distal end of the cable conductor, the cable conductor being slideable within the lead body to extend and retract the electrode relative to the distal end of the lead body. |
US11253698B2 |
Method for positioning terminal end of pacemaker lead, which has passed through coronary sinus, in interventricular septum
The present invention relates to a method for positioning a tip of a pacemaker lead that has passed through coronary sinus into an interventricular septum. More particularly, it relates to a method for positioning a tip of a pacemaker lead that has passed through a coronary sinus into an interventricular septum in order to more effectively transmit an electrical stimulus in a treatment using a pacemaker for patients with arrhythmia.A method of positioning a tip of a pacemaker lead, which has passed through a coronary sinus, into an interventricular septum, in order to effectively transmit electrical stimulus, includes: inserting into an intervention wire through a superior vena cava and a coronary sinus to pass through the interventricular septum and then guiding the intervention wire to an inferior vena cava; and positioning the tip of the lead into the interventricular septum by inserting the pacemaker lead along the intervention wire. |
US11253693B2 |
Catheter device
The catheter device comprises a drive shaft connected to a motor, and a rotor mounted on the drive shaft at the distal end section. The rotor has a frame structure which is formed by a screw-like boundary frame and rotor struts extending radially inwards from the boundary frame. The rotor struts are fastened to the drive shaft by their ends opposite the boundary frame. Between the boundary frame and the drive shaft extends an elastic covering. The frame structure is made of an elastic material such that, after forced compression, the rotor unfolds automatically. |
US11253690B2 |
Circulatory assist device
An example medical device is disclosed. The example medical device includes a tubular scaffold having an inner surface and an outer surface. The medical device also includes a flexible inner member extending along at least a portion of the inner surface of the scaffold. Further, the medical device includes an activation assembly positioned along a portion of the inner member, the activation assembly including a conductive member having a first end region and a second end region, wherein a portion of the first end region is coupled to an activation element, and wherein the second end region is coupled to a power source. Additionally, the power source is configured to deliver an electrical stimulus to the activation element which shifts the inner member between a first configuration and a second expanded configuration. |
US11253688B2 |
Induction heating systems
A method of making and using a medical delivery device includes forming a first compartment to contain at least a portion of an activator, where forming the first compartment includes forming a first wall with a first ferrous material such that the first wall disintegrates in response to first electromagnetic radiation received by the first ferrous material. Upon contact, the activator activates one or more molecular nanomachines. The method also includes forming a second compartment adjacent to the first wall of the first compartment to contain the one or more molecular nanomachines. The second compartment includes a second wall that includes a second ferrous material. The second wall is configured to disintegrate and release one or more activated molecular nanomachines into a patient in response to second electromagnetic radiation received by the second ferrous material. |
US11253687B2 |
Cleansing swab for needle pen assembly
A needle cap assembly for use in combination with a needle pen comprising: (i) a needle cap having a needle cannula for injecting a fluid medication into an injection site, (ii) an internal cap configured to be disposed over an injection end of the needle cap, (iii) an external cap having a cavity configured to envelop the internal and needle caps, (iv) a sealing tab configured to seal a cavity of the external cap for enclosing or housing the needle cap assembly, and (v) a cleansing swab disposed in internally of the needle cap assembly. The cleansing swab is disposed internally of the needle cap and includes an absorptive material loaded with a cleansing fluid to clean an injection site prior to injection of fluid medication. |
US11253686B2 |
Swallowable drug delivery device and methods of drug delivery
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. |
US11253685B2 |
Implantable shunt systems and methods
The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes interatrial shunting systems that include a shunting element having a lumen extending therethrough that is configured to fluidly couple the left atrium and the right atrium when the shunting element is implanted in a patient. The system can also include an energy receiving component for receiving energy from an energy source positioned external to the body, an energy storage component for storing the received energy, and/or a flow control mechanism for adjusting a geometry of the lumen. |
US11253672B2 |
Sleep apnea treatment system and improvements thereto
A valve structure for treating a patient suffering from obstructive sleep apnea is provided. The valve structure is connected to an air flow generator and is connected to a mask that covers at least the nostrils of a patient. The valve structure includes an inlet pressure port attached to the air flow generator and an expiration valve that includes an expiratory membrane, a primary seat and a secondary seat. During inspiration, the expiratory membrane forms a seal with the primary seat, and during expiration, the expiratory membrane forms a seal with the secondary seat. |
US11253671B2 |
Inhaler component
The invention relates to an inhaler component for forming a vapor/air mixture or/and condensation aerosol by evaporation of a liquid material and, if appropriate, condensation of the formed vapor, comprising: an electric heating element for evaporating a portion of the liquid material; a wick with a capillary structure, which wick forms a composite with the heating element and automatically supplies the heating element with the liquid material; a carrier plate, preferably a printed circuit board, which carries the composite and on which the heating element is electrically contacted; a capillary gap formed at least partially by the carrier plate and automatically supplying the composite with the liquid material, by means of an end portion of the wick extending into the capillary gap; a liquid container which contains the liquid material and from which the capillary gap draws the liquid material. In order to achieve a compact overall arrangement, it is proposed that the capillary gap at least partially covers the liquid container on the outside, in a view perpendicular to the carrier plate. |
US11253668B2 |
Strap assembly, strap connector, headgear, headgear assembly, method of forming headgear, tubular connector, patient interface and method of joining straps
FIGS. 1-16D & 66A-92D disclose a large variety of methods of forming the headgear for use in combination with a breathing apparatus including a unitary plastic core within textile casings. In some configurations, the plastic core material penetrates or bursts-through the textile casing of the straps. Some configurations include over moulding, alignment posts, T-joints and joint housings with injection aperture. FIGS. 17-65 & 93A-94C disclose a large variety of different headgear arrangements including top strap, front strap, rear strap and pairs of straps extending from the mask above and below the ear to meet behind the ear. FIGS. 95-121B disclose a large variety of connectors connecting the headgear assembly to the mask assembly where the headgear, mask and connector form a closed loop the connector is disengaged with the mask assembly. |
US11253665B2 |
Larynx mask having a connector
A larynx mask is provided that comprises a dorsal cover plate with an inflatable cuff integrally formed thereon and a tube connecting connector having an insertion section for connecting to an insertion tube. Two separate lumens are provided in the region of the insertion section, these being the esophageal lumen and a respiration lumen. These two lumens are separated from each other by a separating and supporting, wall. The separating and supporting wall extends from the insertion section to the tip of the larynx mask. While the esophageal lumen opens into an esophageal outlet at the proximal end of the mask, the respiration lumen opens in the ventral direction and is closed in the proximal direction close to the tip of the mask. Such a larynx mask is produced in one piece by way of injection of molding and is reinforced by the separating or supporting wall to prevent kinking. |
US11253660B2 |
Aerosol-generating devices and aerosol-generating systems
An aerosol-generating system includes an aerosol-generating device and at least two consumables. Each consumable includes an aerosol-forming substrate. The aerosol-generating device further includes a device housing comprising at least two receiving chambers, wherein each consumable is accommodated in a separate receiving chamber of the at least two receiving chambers. The aerosol-generating device further includes at least two mouthpieces, wherein each mouthpiece of the at least two mouthpieces is aligned with a separate consumable of the at least two consumables and wherein the aerosol-generating device is configured to isolate airflows through separate, respective mouthpieces of the at least two mouthpieces. |
US11253658B2 |
Personal inhaling device
A personal inhaling apparatus is provided. The apparatus includes an ultrasonic personal inhaler with ultra-fine mist transducer that delivers both cool and warm mist using a heater, a face mask, a fluid supply means, and a power source including batteries and/or corded power supply. The apparatus may include a receptacle for a scented pad placed in contact with the heater. Indicators functioning in a pre-determined manner provide indication on if the device is delivering a cool mist, a warm mist, is switched-OFF, a level of charge of a power source, and a level of the fluid in the fluid supply means. |
US11253653B2 |
Segmented piston rod for a medication delivery device
A segmented piston rod for an injection device includes multiple segments joined together via a hinge located on one side of each segment. The piston rod can be bent in one direction by articulating subsequent hinges while an axial force can be transmitted by the segmented piston rod to the stopper when the subsequent hinges are closed and the segments abut each other opposite to the one side of the hinge. The segmented piston rod is secured against rotation relative to the housing around the longitudinal axis of the segmented piston rod. The segmented piston rod has a last element which abuts the stopper in the reservoir and a first segment which is opposite to the last segment. The first segment is includes an internal thread matching an external thread of a drive sleeve and rotation of the drive sleeve advances the piston rod towards the stopper of the reservoir. |
US11253651B2 |
Medicament delivery device
A medicament delivery device (100) for delivery of medicament through a cannula (132) from a cartridge (10), the device comprising a first container (11) for storage of a first substance, a second container (12), and valve means for closing a distal end of the second chamber (12), the second container (12) being arranged coaxially with respect to the first container (11), a mixing element (304) being provided for causing displacement of the second substance into the first container (11) through the valve means in a mixing stroke, a release element being provided for holding the mixing element (304) in an initial position and being operable to release the mixing element (304) to initiate the mixing stroke, there being a needle shroud (400) for shrouding the cannula, and removal of the needle shroud (400) from the cannula (132) causing operation of the release element. |
US11253648B2 |
Multi-chamber injection device
A multi-chamber injection device includes multiple syringes. The multiple syringes may be arrayed in a circular, linear, or other format. In some implementations, a needle, port, or similar may be shared by all the syringes in configuration that allows only one syringe to deliver contents at a time while blocking the other syringes from delivering their respective contents. In some implementations, the syringes may be all stored in the same container. One or more of the chambers of a multi-chamber injection device may be preloaded with medication. Different medications may be loaded into different chambers. The medications may be selected to treat the same medical condition. |
US11253643B2 |
Apparatus for securely and gently holding a flexible elongated medical device
A clip for holding a flexible elongated medical device. In embodiments, the clip has a hinge; first and second jaws movable with respect to each other about the hinge from a closed position to an open position, each of the jaws having a contact surface, the contact surface of the first jaw being disposed against the contact surface of the second jaw when the clip is in the closed position and away from the contact surface of the second jaw when the clip is in the open position; and flexible material disposed on at least one of the jaws, the flexible material comprising the contact surface. The invention also includes methods of holding a flexible elongated medical device. |
US11253642B2 |
Perfusion system
A perfusion container for directly administering to patients a dose of an antineoplastic drug calculated according to a patient's parameter, wherein the first perfusion container comprises a solution of antineoplastic drug at a concentration and volume such that the amount of antineoplastic drug in the container is equal to the calculated dose for one patient but less than the calculated dose for a second patient, the calculated dose is provided to first patient within 5% variance by directly administering the full volume of the solution of antineoplastic drug from the first perfusion container, further the first perfusion container is accompanied by a second top-up perfusion container comprising a solution of antineoplastic drug at a concentration and volume such that the calculated dose is provided within 5% variance by directly administering the full volume of the solution of antineoplastic drug from the first perfusion container and the second top-up container to the second patient. |
US11253640B2 |
Fluid management apparatus and method
In one example embodiment, a vibration apparatus can augment and enhance negative-pressure therapy systems. The apparatus can be attached to an external surface of a dressing, fluid conductor, or other components. The apparatus can generate low-amplitude vibrations, which can be transmitted through the components. Kinetic energy of the oscillations can agitate fluid in the components, which can lower the viscosity of the fluid and reduce the frequency of blockages in fluid conductors. Vibrations may also agitate a tissue site, which can encourage blood flow and granulation. |
US11253639B2 |
Reduced pressure therapy apparatuses and methods of using same
Some embodiments comprise a pump assembly for reduced pressure wound therapy, comprising a housing, a flow pathway through the pump, one or more valves in communication with the flow pathway, a pump supported within or by the housing, and a one-way flow valve in fluid communication with the pump. The pump assembly can have a pressure sensor in communication with the flow pathway through the pump, and at least one switch or button supported by the housing, the at least one switch or button being accessible to a user and being in communication with the controller. The one-way flow valve can be configured to substantially prevent a flow of gas through the one-way flow valve in a direction of flow away from the pump. The pump assembly can have a controller supported within or by the housing, the controller being configured to control an operation of the pump. The pump has been sterilized following the assembly of the pump such that an inside and an outside of the housing, the flow pathway, the one or more valves, the pump, the controller, the battery compartment, and the at least one switch or button have been sterilized. |
US11253638B2 |
Monitoring device and method for monitoring an extracorporeal blood treatment device
A device and method are used for monitoring an extracorporeal blood treatment device, such as a dialysis machine, which includes an extracorporeal blood circuit having an arterial blood line with an arterial patient port and/or at least one venous blood line with a venous patient port, and a dialysis fluid system which has a dialysis fluid supply line and a dialysis fluid drain line. The monitoring device selects and senses a measured value during operation of the extracorporeal blood treatment device which is suitable for monitoring the blood treatment device to compare a time-related actual course of the measured value with a target course of the measured value stored in a memory, and to determine that there is a defect if, at least in sections, the actual course of the measured value deviates from the target course by more than a defined tolerance. |
US11253636B2 |
Disposable components for fluid line autoconnect systems and methods
Components for a medical infusion fluid handling system, such as an APD system, in which one or more lines (such as solution lines), spikes or other connection ports may be automatically capped and/or de-capped. This feature may provide advantages, such as a reduced likelihood of contamination since no human interaction is required to de-cap and connect the one or more lines, the spikes or the other connection ports. For example, a fluid handling cassette may include one or more caps that cover a corresponding spike and include a raised and/or recessed feature to assist in removal of the one or more caps from the cassette. A solution line cap may include a hole and a recess, a groove or other feature to engage with a spike cap and enable removal of the spike cap. |
US11253634B2 |
Cationic steroidal antibiotic compositions for the treatment of dermal tissue
This disclosure relates to dermal treatment compositions, such as dermal fillers and tissue glues, and injectable compositions that incorporate one or more cationic steroidal antimicrobials (CSAs). The CSAs are incorporated into the dermal treatment compositions to provide effective antimicrobial, anti-inflammatory, analgesic, anti-swelling and/or tissue-healing properties. A treatment composition includes a component formed from a biologically compatible material suitable for injection into and/or application onto tissue at a treatment site. One or more CSA compounds are mixed with the biologically compatible material so that the one or more CSA compounds are incorporated within the composition, forming a reservoir of CSA compounds within the resulting bolus of the treatment composition after injection and/or application. |
US11253628B2 |
Neurogenic regulation of bone growth and bone degradation
This disclosure relates to methods for promoting bone formation or reducing bone destruction. This disclosure also relates to methods for promoting the recruitment of mesenchymal stem cells (MSCs) to a local site of injury or surgical intervention in bone to promote healing. In addition, this disclosure relates to methods for reducing or preventing mineral formation or bone growth, or reducing bone mass. The methods disclosed herein are useful for treating conditions such as osteopetrosis or osteoradionecrosis. |
US11253626B2 |
Use for peptide uniquely binding to vascular endothelial cells, and peptide
Provided is a use for a peptide in surface-treating a medical device or medical material to be used in contact with blood, with which it is possible to obtain a medical device or medical material that can achieve highly efficient vascular endothelialization through the use of a peptide uniquely binding to vascular endothelial cells. Also provided are: a peptide suitable for use in said surface treatment; a method for producing a medical device or medical material surfaced-treated with said peptide and to be used in contact with blood; and a surface treatment agent including said peptide, said agent to be used in surface-treating a medical device or medical material to be used in contact with blood. In the present invention, a medical device or medical material is surface-treated using a peptide that includes any one of ten specific amino acid sequences and uniquely binds to the surface of endothelial progenitor cells. |
US11253625B2 |
Ophthalmic device packaging solutions comprising a poloxamine/erythritol mixture
A packaging system for storing ophthalmic devices such as contact lenses and methods for packaging such ophthalmic devices with solutions is disclosed. The packaging system contains an unused, ophthalmic device in an aqueous packaging solution comprising tris(hydroxymethyl)aminomethane or a salt thereof; wherein the solution has an osmolality of at least about 200 mOsm/kg and a pH in the range of about 6 to about 9. |
US11253610B2 |
Plant virus particles for delivery of antimitotic agents
Anti-lymphoma plant virus particles are described. The anti-lymphoma plant virus particles include a filamentous or rod-shaped plant virus particle linked to an antimitotic agent. A therapeutically effective amount of an anti-lymphoma plant virus particle can be administered to a subject to provide a method of treating lymphoma. |
US11253604B2 |
Conjugate of methotrexate and peptide
The present invention relates to a compound having a structure in which methotrexate and a peptide are connected via a covalent bond, and an anticancer or anti-inflammatory pharmaceutical composition comprising same. The compound having a structure in which methotrexate and a peptide are connected via a covalent bond of the present invention has excellent biological activity such as anticancer or anti-inflammatory action and has markedly reduced toxicity with respect to cells, and thus, may be usefully used in various fields such as medicine and medical supplies. |
US11253600B2 |
Bioorthogonal compositions
Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections. |
US11253599B2 |
Analgesic preparation with nanocarriers and use thereof
The invention relates to the field of analgesics. According to the invention, a kit or composition, particularly a pharmaceutical composition or a pharmaceutical kit, is provided, comprising a nanocarrier which is a hyperbranched polymer, such as a dendritic polymer or dendrimer, preferably having a molecular weight of 1,000-100,000 g/mol, and an analgesic which, when administered without nanocarrier, has both peripheral and central analgesic effect, preferably an opioid such as nalbuphine. According to the invention, the analgesic in this composition mainly or exclusively has a peripheral effect and thus reduces side effects triggered by the activation of central or intestinal opioid receptors. It is used for the treatment of peripheral pain and/or inflammation. The invention also relates to particularly suitable nanocarriers. |
US11253598B2 |
Pharmaceutical composition containing anionic drug, and preparation method therefor
Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug delivery containing: an anionic drug as an active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the anionic drug formed a complex with the cationic lipid, and the complex is encapsulated within a micelle structure formed by the amphiphilic block copolymer and the polylactate. |
US11253597B2 |
Polymer hydrogels for in vivo applications and methods for using and preparing same
Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated. |
US11253595B2 |
Treatment for reducing adverse events including chemotherapy discomfort and other conditions
This disclosure relates to treatments for reducing the side effects associated with treatment of a medication or drug, such as a chemotherapy medication, being experienced by a patient. This may be accomplished by administering to a patient taking the medication, a buffered aqueous liquid having a pH of about 10 to about 11.5, wherein the buffered aqueous liquid comprises sodium bicarbonate, sodium carbonate, and trisodium phosphate. |
US11253591B2 |
Combination of lenalidomide and polypeptide construct, and uses thereof
Methods for cancer treatment include administering to a cancer patient an anti-CD38 antibody-attenuated human IFN alpha-2b construct and lenalidomide or pomalidomide. Tumors that may be treated according to these methods include tumors which comprise CD-38 expressing tumor cells, including B-cell lymphoma, multiple myeloma, non-Hodgkin's lymphoma, chronic myelogenous leukemia, chronic lymphocytic leukemia, and acute lymphocytic leukemia. |
US11253586B2 |
Coronavirus vaccine formulations
Disclosed herein are coronavirus Spike (S) proteins and nanoparticles comprising the same, which are suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed. |
US11253584B2 |
Influenza virus vectors and uses therefor
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination. |
US11253582B2 |
Chlamydia-activated B cell platforms and methods thereof
Disclosed herein is a Chlamydia-activated B cell (CAB) platform. Also disclosed is a method of enhancing a population of B cells, comprising exposing said B cells to Chlamydia spp. under conditions suitable to enhance the population of B cells, such that expansion and differentiation of said B cells takes place, and said B cells are exposed or crosslinked to an antigen. Also disclosed are methods of producing said CABs, and treating a subject in need thereof with said CABs. |
US11253581B2 |
Composition for preventing or treating Mycoplasma synoviae infection
The present disclosure relates to a composition for preventing and treating Mycoplasma synoviae infection, the composition comprising Tuf, NOX, MS53-0285 or a combination thereof as active ingredients. The composition of the present disclosure is effective in alleviating symptoms caused by Mycoplasma synoviae infection and can be used as an effective tool in preventing or treating poultry diseases. |
US11253573B2 |
Compositions and methods for treating heart failure
The present invention provides methods for treating chronic heart failure patients using the medication comprising neuregulin. The methods comprise first performing a companion diagnostic test of each patient before treatment; and then providing a suitable treatment to the patient according to the results of the companion diagnostic test. When the result of the test is within a favorite treatment zone, the patient is suitable for heart failure treatment by administering an effective amount of neuregulin. |
US11253565B2 |
Nanoparticle ophthalmic composition for the treatment of ocular disorders or diseases
Is herein described a nanoparticle ophthalmic composition comprising at least 0.1% of Perilla frutescens extract and at least 0.1% of hyaluronic acid or a salt thereof wherein the Perilla frutescens extract has a content of polyphenols of at least 2.5% by weight of the total weight of the extract and to the use of said ophthalmic composition in the treatment of ocular disorders or diseases such as tear dysfunction syndrome, dry eye, diabetic retinopathy and glaucoma, preferably in the treatment of tear dysfunction syndrome. |
US11253558B2 |
Optimized oncolytic viruses and uses thereof
Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer treatments. Also disclosed are methods of creating synthetic viruses for targeting cancerous tumors. |
US11253555B2 |
Food composition and pharmaceutical composition for inhibiting Sjogren's syndrome each containing Bifidobacterium pseudocatenulatum C-RAPO (KCTC13986BP) and Bifidobacterium bifidum ATT (KCTC13474BP)
Disclosed are Bifidobacterium pseudocatenulatum C-RAPO (KCTC13986BP) and Bifidobacterium bifidum ATT (KCTC13474BP) strains that have the effects of inhibiting sialoadenitis, which is a symptom of the Sjogren's syndrome, and inhibiting a reduction in saliva flow rate. Based on this, these strains can be used for prevention or treatment of Sjogren's syndrome and can be developed into food, health food and pharmaceuticals. |
US11253554B2 |
Bacterial profile to detect fungal taxa abundance in the gut
Disclosed herein are compositions and methods for diagnosing fungal dysbiosis in the gut of a subject with cirrhosis that involves assaying a sample from the subject for bacterial taxa. These compositions and methods are based on the discovery that there is significant correlation between fungal and bacterial diversity in gut microbiota of cirrhotic patients. Therefore, disclosed herein is a method for treating a subject with liver cirrhosis that involves assaying a gut sample from the subject for bacterial taxa to generate a bacterial profile, comparing the bacterial profile to control profiles to predict fungal dysbiosis; and treating the subject for fungal dysbiosis. |
US11253552B2 |
Process for producing egg yolk with high content of AF-16
The present invention relates to a process for producing an egg yolk with a very high content of antisecretory factor (AF) proteins, in particular with a very high content of AF protein fragment consisting essentially of the amino acid sequence as shown in SEQ.ID.NO.1 (AF-16) and/or in SEQ.ID.NO.2 (AF-8), said process comprising for at least 4 weeks feeding a poultry, such as a hen, an AF-16 inducing pelleted feed for poultry comprising at least 0.14% free tryptophan, such as 1-2 g tryptophan/kg feed, and thereafter harvesting egg from said poultry, separating egg yolk from egg white, and alternatively spray-drying, grinding, leaching, extracting, evaporating, membrane filtrating, and/or or freeze-drying said egg yolk.The present invention further relates to said egg yolk with a very high content of antisecretory factor (AF) proteins, produced according to the herein described process, and to their use for the preparation of functional food products and pharmaceutical products for the treatment and prophylaxis of abnormal physiological conditions caused e.g. by exceptionally high levels of body fluid discharge. The invention also relates to food products and pharmaceutical products so prepared. |
US11253550B2 |
Method for treating fibrotic liver disease
The purpose of the present invention is to provide a novel therapeutic agent for liver disease. The present invention is a mesenchymal stem cell characterized by high expression of the Tissue Factor Pathway Inhibitor (TFPI). It is preferable that the mesenchymal stem cell is allogeneic and is derived from a fatty tissue. Moreover, the present invention includes a therapeutic agent for liver disease containing the mesenchymal stem cell. |
US11253547B2 |
CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
Provided for herein in several embodiments are immune cell-based (e.g., natural killer (NK) cell) compositions comprising CD19-directed chimeric antigen receptors. In some, embodiments the anti-CD19 binder portion of the CAR is humanized. In several embodiments, the humanized anti-CD19 CAR expressing cells exhibit enhanced expression of the CAR as well as enhanced cytotoxicity and/or persistence. Several embodiments include methods of using of the anti-CD19 CAR expressing immune cells in immunotherapy. |
US11253540B2 |
Composition including glycosaminoglycan derivative and chemokine receptor activity regulator
Provided are a composition comprising a GAG derivative and a chemokine receptor activity regulator, and a pharmaceutical composition comprising said composition. |
US11253539B2 |
Antithrombotic medical material using nickel titanium alloy
A medical material uses a nickel-titanium alloy wherein a polyelectrolyte has a reduced thickness while a sufficient amount of an antithrombogenic compound for production of a therapeutic effect is supported. The medical material in which a porous surface is formed on a nickel-titanium alloy to allow infiltration of a polyelectrolyte into the pores, to thereby reduce the thickness of the polyelectrolyte exposed on the surface of the nickel-titanium alloy while allowing supporting of a sufficient amount of an antithrombogenic compound due to contribution of the polyelectrolyte infiltrate. |
US11253533B1 |
Water dissolvable macrocyclic lactone cyclodextrin complexes
Injectable Ivermectin solution is safely administrable to humans and animals used the disclosed technology. A macrocyclic lactone cyclodextrin complex which is completely dissolvable or dissolved in water in a ratio of at least 5 or 10 mg of macrocyclic lactone to 1 mL of water. The macrocyclic lactone cyclodextrin complex is non-toxic, without using organic solvents, and in embodiments, formed by adding a surfactant to the macrocyclic lactone complex to water. The macrocyclic lactone cyclodextrin complex is Ivermectin or an Ivermectin derivative in some embodiments. The cyclodextrin complex is 2-hydroxypropyl-beta-cyclodextrin in some embodiments of the disclosed technology. The surfactant can be polysorbate 80 and is in a ratio of 0.01% to 25%, by weight, to said water. The water soluble complexes can be added to the water. The water-soluble complexes can have at least one of an anti-parasitic, anti-viral and anti-cancer complex. |
US11253527B2 |
Method and composition for inhibiting virus infection
The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof. |
US11253526B2 |
Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases
Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases. |
US11253520B2 |
Pulse dosing regimen and methods of treatment
A novel dosing regimen for erlotinib or a pharmaceutically acceptable salt thereof is described herein. The dosing regimen demonstrates impressive control of central nervous system disease, which is better than that reported with standard dose erlotinib. The use of the novel dosing regimen for treating patients in need thereof, including for controlling formation of metastatic brain, leptomeninges, or CNS lesions in a patient with non-small cell lung cancer (NSCLC) that harbors epidermal growth factor receptor (EGFR) mutation with or without pre-existing brain metastases, is also described herein. |
US11253518B2 |
Methods and compositions for the treatment of hair loss
Compositions and methods for the treatment of hair growth and the prevention of hair loss. |
US11253515B2 |
Pharmaceutical compositions and dosage forms
Disclosed herein are pharmaceutical compositions and dosage forms including N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino) benzamide that are useful in the treatment of subjects having cancer. The present disclosure also provides methods for preparing these pharmaceutical compositions and dosage forms, and methods of treating subjects having cancer utilizing the pharmaceutical compositions and dosage forms provided herein. |
US11253514B2 |
Triple combination of pure 5-HT6 receptor antagonists, acetylcholinesterase inhibitors and NMDA receptor antagonist
The present invention relates to a combination of pure 5-HT6 receptor antagonist, acetylcholinesterase inhibitor and NMDA receptor antagonist. Also, the present invention provides pure 5-HT6 receptor (5-HT6R) antagonists, or the pharmaceutically acceptable salt(s) thereof in combination with or as adjunct to acetylcholinesterase inhibitor and N-Methyl-D-aspartate (NMDA) receptor antagonist and their use in the treatment of cognitive disorders. The invention further provides the pharmaceutical composition containing the said combination. |
US11253513B2 |
Dosing regimen for injectable cetirizine
Described herein is a method of administering injectable cetirizine or levocetirizine including intravenously injecting a mammal in need thereof with a therapeutically effective amount of an injectable cetirizine or levocetirizine composition, wherein the mammal receives a maximum daily dose of the cetirizine or levocetirizine that is no more than 15 times a maximum recommended daily clinical dose for the mammal. |
US11253510B2 |
Anti-neutrophil activity on innate immune response
Disclosed are compositions, medical devices and methods for ameliorating sterile injury due object use in a subject in need thereof. More particularly, the present disclosure relates to compositions including N-Acetylcysteine and an aminoquinoline. The present disclosure also relates to compositions including an endonuclease and an aminoquinoline. The present disclosure also relates to medical devices including a coating comprising N-Acetylcysteine, an aminoquinoline, an endonuclease, and combinations thereof. |
US11253506B2 |
Compounds, compositions and methods for preventing and/or treating chlorine inhalation toxicity and/or injury
The present invention includes compounds, compositions and methods for treating and/or preventing chlorine inhalation toxicity and/or injury in a subject subjected to chlorine inhalation. |
US11253504B2 |
Compositions of a polyorthoester and an aprotic solvent
Delivery systems and compositions comprised of a biodegradable polyorthoester polymer, an aprotic solvent, and a drug are described. The solvent is selected to modulate release of drug from the composition, where, in some embodiments, the solvent is rapidly released after administration and provides a corresponding rapid rate of drug release. Alternatively, in other embodiments, the solvent is slowly released from the composition after its administration, and provides a correspondingly slow rate of drug release. |
US11253503B2 |
Inhibitors of SARM1 NADase activity and uses thereof
The present disclosure provides compounds useful as inhibitors of SARM1 NADase activity, compositions thereof, and methods of using the same. The present disclosure provides compounds useful for treating a neurodegenerative or neurological disease or disorder, compositions thereof, and methods of using the same. |
US11253502B2 |
Tie-2 activators targeting the Schlemm's canal
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for eye conditions, for example, intraocular pressure, ocular hypertension, and glaucoma. |
US11253492B2 |
Bupropion as a modulator of drug activity
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan. |
US11253484B2 |
Transdermal absorption preparation
Provided is a transdermal absorption preparation having superior drug skin permeability, which can uniformly disperse the drug in the preparation and maintain the uniform dispersion state of the drug.A transdermal absorption preparation having a plaster layer containing a drug, a polymer and a pH adjuster, in which the aforementioned polymer contains a polymer having a particular glass transition temperature of 30° C.-200° C., and the surface of the plaster layer has a pH of 6.7-10.0. |
US11253483B2 |
Protease assisted native-protein delivery approach (PANDA)
A method for intracellular delivery of single proteins or other cargo molecules by encapsulation within nanocapsules formed by interfacial polymerization of one or more types of monomers and selected protease cleavable cross-linkers is provided. The thin positively charged capsules are readily brought into the cytosol of target cells by endocytosis. The capsules are degraded by the action of endogenous proteases or co-delivered proteases on the cross-linkers releasing the functional cargo unaltered. The cross-linkers can be adapted to be cleavable by specific enzymes selected from available intracellular enzymes within the target cell or co-delivered or self-cleaving when the cargo itself is a protease. The nanocapsules produced by the methods have been shown to have long-term stability, high cell penetration capability, low toxicity and efficient protease-modulated specific degradability without affecting cargo protein function. |
US11253481B1 |
Self-nanoemulsifying 3D-printed tablet composition and method of use thereof
Provided are a self-nanoemulsifying 3D printer ink composition and a method of using such composition to manufacture a 3D-printed tablet having compartmentalized active pharmaceutical ingredients. In particular, the 3D-printed tablet composition includes glimepiride and/or rosuvastatin in a curcuma oil based self-nanoemulsifying drug delivery system (SNEDDS). |
US11253479B2 |
Hydrobromide salt of an anti-HIV compound
Solid dispersions and dosage forms comprising the hydrobromide salt of a diarylpyrimidine derivative, useful as an anti-HIV agent. |
US11253477B2 |
Compositions based on propolis nanocapsules which can be used as carriers for substances of interest, methods for producing same and use thereof
A process for obtaining compositions constituted by propolis nanoparticles is disclosed. The nanoparticles are optionally associated to a substance of interest such as active ingredients, and, optionally, substances of secondary effect such as synergists and adjuvants. The process includes preparing a fraction A, which consists of propolis extract dissolved in an organic solvent, to which stabilizer and/or emulsifier may be added, and, optionally, substances of interest and/or of secondary effect; ii) preparing a fraction B, aqueous phase, constituted by: (ii.1) water; or (ii.2) an aqueous solution or dispersion, to which stabilizer and/or emulsifier may be added; (iii) dropping the fraction A onto the fraction B or vice versa; iv) homogenizing the mixture by stirring and spontaneous formation of nanoparticles with average size from 1 to 1000 nm in a dispersion; and v) optionally (v-1) removing organic solvent and/or (v-2) drying the nanodispersion. |
US11253461B2 |
Matte nail compositions containing polylactic acid microparticles
The invention relates to matte nail compositions including polylactic acid microparticles, as well as to methods, kits and nail composition sets related to such compositions. |
US11253460B2 |
Cosmetic compositions
Disclosed are compositions and methods for their use that can be used individually or in combination. The compositions have the ability to treat a wide range of skin and skin conditions, and particularly men's skin. |
US11253456B2 |
Anti-inflammatory peptides, and uses thereof
An anti-inflammatory peptide comprises an anti-inflammatory fragment of a protein selected from SEQ ID NOs: 1 to 16, the anti-inflammatory fragment being 7 to 37 amino acids in length and having a charge of between −9 and +3; wherein the c-terminal amino acid is not cysteine (C) or methionine (M), and the n-terminal amino acid is not cysteine (C), histidine (H), proline (P) or threonine (T). The anti-inflammatory fragment does not contain cysteine (C). The anti-inflammatory fragment is from a region of the proteins of SEQ ID NOs: 1 to 16, which region is characterised by being 17 to 109 amino acids in length and having a charge of between −6 and +4, wherein the c-terminal amino acid of the region is not aspartic acid (D), phenylalanine (F), methionine (M) or tryptophan (W), and the n-terminal amino acid of the region is not aspartic acid (D), histidine (H), methionine (M), proline (P) or tryptophan (W). Examples of peptides are provided in SEQ ID NOs: 71 to 221. |
US11253452B2 |
Methods and compositions for combatting color loss
A method of combating colour loss from a dyed material, the method comprising contacting the material with a composition comprising a hydroxy-substituted aldehyde. |
US11253446B2 |
Stable metal ion containing compositions
Disclosed herein are oral care compositions comprising: a) one or more pyrophosphate compounds, wherein the total concentration of pyrophosphate compounds in the composition is 0.5 wt % to 1.5 wt %, based on the weight of the oral care composition; b) one or more thickening gums, wherein the total concentration of thickening gums in the composition is 1.25 wt % to 1.6 wt %, based on the weight of the oral care composition; and c) a metal ion source. |
US11253445B1 |
Oxidative hair color remover in tablet or pellet form
An oxidative composition for the removal of natural and/or synthetic color from keratinaceous fibers may include a pellet or tablet that when added to a sufficient quantity of a peroxide developer solution readily disperses. The composition may include a gas generating agent to facilitate breakdown and dispersion of the pellet or tablet. The composition added to the developer may be agitated to forms homogeneous cream-like mixture for application to keratinaceous fibers. |
US11253436B2 |
Method of making a dental restoration
A method of making a monolithic dental restoration. The method includes the steps of providing a monolithic precursor of a dental restoration and firing the monolithic dental restoration precursor to provide the monolithic dental restoration. The zirconia material of both the dental restoration precursor as well as the dental restoration has a relative density of greater than 98% of the theoretic density of the zirconia material. The invention helps providing a color of a non-glazed dental restoration which resembles the color of a glazed dental restoration. |
US11253432B1 |
Systems, methods, assemblies, and components for medication reminders
To address the widespread problem of half of all patients failing to take prescribed medications as directed by their physicians, the present inventor devised, among other things, one or more medication reminders. For example, one embodiment, particularly suitable for only two- or three-a-day prescriptions, comprises a repositionable indicator mechanism that attaches via a self-adhesive microsuction backing to the top or other surface of a plastic prescription medication bottle. The indicator, which can take the form of a slider that moves between two or three indicator positions, in some cases using a detent locking mechanism, to simultaneously indicate the prescribed dosage frequency, last dosage taken, and remaining dosages for a day. |
US11253427B2 |
Spa with air intake system
A spa has an insulated cabinet with an uninsulated shell disposed therein. A filter assembly is downstream of a water intake. A heater is downstream of the filter assembly and a pump is downstream of the heater. A diversion line is in fluid line connection with an outlet of the pump. An ozonizor is in fluid communication with the diversion line. The filter assembly is coupled to the diversion line. A data processing system is coupled to the heater, pump, a control panel and a temperature sensor, wherein the data processing system responsive to when the actual temperature of an amount of water in the shell is a magnitude in degrees below a set temperature 1) turns the heater off if it is on or does not turn the heater on if it is already off and 2) turns the pump on if it is off or if it is already running does not turn the pump off. |
US11253425B2 |
Pain management device
The invention relates to a pain management device with a body portion having an hourglass shaped, elongated handle with an arm at one end for releasably attaching one or more treatment attachments, one or more generally planar scraping wings for Gua Sha treatment, and a motor inside configured to impart vibration in each of several modes optimized for vibration therapy. The invention may also include a kit with the pain management device, and one or more treatment attachments designed for unilateral or bilateral vibration application adjacent to trigeminal and/or vagus nerves. The treatment attachment may have two or more pivotable arms that extend along an axis generally perpendicular to the elongated handle when attached to the pain management device. |
US11253413B2 |
Integrated dissection board table lid
An anatomy table for use in autopsies and dissections comprises a base and an immersion storage tank arranged in the base. The anatomy table further comprises a dissection lid arranged on the base, wherein the dissection lid covers the immersion storage tank in its closed position. The table also comprises a hinge secured between the dissection lid and a top edge of the base, wherein the dissection lid rotates about the hinge between a first and second position, wherein the first position allows for access to the body stored in the anatomy table immersion storage tank while the second or closed position of the dissection lid allows for dissecting to occur directly on top of the anatomy table. |
US11253411B2 |
Patient support system control using radar
A patient immersion sensor includes a radio detection and ranging (RADAR) apparatus to determine a time of flight (TOF) of a RADAR pulse and a reflected signal that is reflected by a patient or by a portion of a patient support surface supporting the patient. The TOF is indicative of an immersion depth or a distance toward bottoming out of a patient supported on the patient support surface, such as a mattress or a pad. The RADAR apparatus emits pulses of very short duration so as to be able to detect objects, such as a patient or a portion of a mattress or pad, at very close distances. The RADAR apparatus may use time-of-flight (TOF) between transmission of the pulse and receipt of a reflected signal to determine a distance toward bottoming out by the patient, thereby to determine if the patient is properly immersed into the patient support surface. Adjustments to inflation or deflation of one or more bladders are made to achieve a desired immersion amount within a tolerance range between upper and lower TOF thresholds. |
US11253408B2 |
Refastenable disposable garment having a curled edge, and process for making same
A refastenable disposable garment defines a longitudinal direction and a transverse direction, and comprises a first waist region contiguous with a first waist edge. The first waist region defines first and second side edges transversely spaced apart and defines first and second surfaces. The first waist region is elastomeric proximal both the first and second side edges. The garment can include a second waist region and a crotch region that interconnects the first and second waist regions. The garment comprises non-extensible, relatively rigid first and second fastening components attached to the first surface of the first waist region adjacent the first and second side edges, respectively. The first waist region defines first and second flange portions transversely outward of the first and second fastening components, respectively. Each flange portion is transversely curled toward the second surface. A process for making such an article is also disclosed. |
US11253405B2 |
Underpants-type disposable diaper with seepage-minimizing display sheet structure
An underpants-type disposable diaper has outer members that separately or integrally configures a front body and a back body. An inner member is attached to the outer members from the front body to the back body. The outer members have a waist extended section that extends to a side of the waist opening of an edge of the inner member on a waist side. The underpants-type disposable diaper further has a display sheet containing a liquid impervious resin film on an outer side of the inner member in a region in which the outer members and the inner member overlap with each other in at least one of the front body and the back body, in which the display sheet extends from a region overlapping the inner member into the waist extended section. |
US11253400B2 |
Negative pressure wound apposition dressing system
The present disclosure relates generally to the field of medical treatment and therapy of mammalian tissue. More specifically, it relates to coverings and/or dressings that provide negative pressure at mammalian tissue sites, such as at one or more sites of surgical, non-surgical, and/or traumatic wounds, to promote closure and healing of the wounds. A key embodiment of the disclosed invention entails the use of a dressing that comprises a sponge that is shaped so as to create a vector force inward bringing wound edges together to promote healing, especially upon application of negative pressure. Other key features of the disclosed invention are its simplicity, its low cost, and that it is completely mechanical and lacks the need for any electronic components. The disclosure also relates to devices, systems, kits and methods for providing said negative pressure at said mammalian tissue sites and promote healing. |
US11253399B2 |
Wound filling apparatuses and methods
Many embodiments of wound filling devices and methods of their use in systems for the application of negative pressure therapy are described herein. In one embodiment, a wound filling device comprises: an inflatable bag member having at least one fluid carrying conduit operably connected thereto to inflate/deflate said bag member; a separate textured covering sock member at least partially covering the inflatable bag member. Another embodiment comprises a three-dimensional wound packing member, and may optionally comprise a plurality of such members linked together. Certain embodiments of wound packing members may comprise a porous bag member adapted to be non-adherent to the wound. Yet other embodiments may comprise a non-porous bag member provided with means to connect a fluid supply to the interior. |
US11253395B2 |
Systems and methods for generating and applying biomimicry tear films
Systems and methods are provided for generating and applying artificial tear film layers to a cornea surface. An example method includes forming an artificial tear film that is optically transparent, ultra-thin, and smoothly conforming to cornea surface. The artificial tear film includes a lipid layer that prevents evaporation of moisture from the cornea (e.g., from the underlying aqueous layer of the artificial tear film, and/or from the natural tear film on the cornea, etc.). A dispenser, such as an atomizer/nebulizer/micronizer, can be used to generate and applying the artificial tear film layers, especially the lipid layer, with reduced dispensing volume and average droplet size, etc., such that the deposit thickness of the artificial tear film layers remains thin and better spreads and conforms to the surface of the cornea, as compared to the results of conventional eye droppers dispensing conventional artificial tears. |
US11253391B2 |
Systems and methods for delivering biomaterials
Delivery systems and methods for forming and delivering biomaterials from two components are described herein. In particular, apparatus and methods for performing controlled delivery of multicomponent delivery of biomaterials into or onto a body part, such as a body lumen are described. More specifically, in some embodiments, the apparatus and methods are directed towards controlled delivery of micro-volumes of biomaterials into or onto a target location, the micro-volumes being defined as 0.001 mL-1 mL (or 1 μL-1,000 μL) of volume. |
US11253388B2 |
Ostomy barrier
An ostomy barrier includes an adhesive layer having a body-facing side, a distal side opposite to the body-facing side, and an opening, a seal substantially aligned with the opening, the seal having an aperture configured to receive a stoma therein, and a flexible connector extending between the seal and the adhesive layer to connect the seal to the adhesive layer. The flexible connector formed from a flexible material to allow relative movement between the seal and the adhesive layer. |
US11253387B2 |
Anatomical ring with discrete thumping element
An anatomical ring device for attachment to a penis includes a ring body defining an interior opening that is shaped and sized to receive a penis. A stimulation unit is disposed on one side of the ring body. A discrete stimulation element is movably disposed on the stimulation unit. A motor is disposed within the stimulation unit. The motor is operably connected to the discrete stimulation element to cause independent movement thereof relative to the stimulation unit. |
US11253380B2 |
Absorbable stent
An absorbable stent includes an absorbable matrix. The matrix includes a number of wave-shaped rings connected by connection units and arranged in an axial direction. The wave-shaped ring includes a number of waves arranged in a circumferential direction. A peak, a valley and a support connecting the peak and the valley form the wave. Two adjacent wave-shaped rings and the connection unit form a closed side supporting unit. The matrix has a volume of [4, 40] μm per unit blood vessel area. The absorbable stent has sufficient radial supporting strength for clinical applications. Moreover, the volume of the matrix per unit blood vessel area is less than volumes of existing stents. When the absorbable stent and existing stents are made of the same material, the absorbable stent has a shorter degradation and absorption cycle. |
US11253377B2 |
Prosthetic suspension mounting assembly
A prosthetic suspension-mounting system which employs an improved flathead bolt and socket centering cup combination for securement of an amputee-limb enveloping liner within a prosthesis. The liner has a strap fixedly attached on the bottom end of the liner by a flathead bolt. The mounting system also includes a containment socket for seating the liner in the prosthesis using the head of the flathead bolt as a bearing surface against a floor of the socket. The containment socket has a slot there through at a position corresponding to the strap of the liner. The socket is provided with a disk-shaped recess having a flat floor, and the liner is provided with a distal flathead bolt having a flat head to provide a direct bearing surface against the floor of the socket. This provides a delimited bearing surface to keep the liner substantially centered within the prosthesis while still affording a lateral degree of freedom to avoid concentration of lateral forces. |
US11253376B2 |
System for distracting and measuring an intervertebral space
Systems and methods for distracting an intervertebral disc space are provided. The systems use an expandable trial with telescopic stabilizers. The systems and methods of distracting an intervertebral space are provided in a manner that addresses the problem of subsidence. The method includes inserting the trial into the intervertebral space in a collapsed state and, once inserted, the trial is then used for distracting the intervertebral space using an expansion that includes a first stage and a second stage. The first stage includes expanding the trial laterally toward the peripheral zones of the top vertebral plate and the bottom vertebral plate, and the second stage includes expanding the trial vertically to distract the intervertebral space. |
US11253375B2 |
Device for positioning a resurfacing prosthesis and method of assembling said device
Disclosed is a device for positioning a resurfacing prosthesis, including: a gripping and handling instrument for a main body of a resurfacing prosthesis; a connecting body, interposed between said gripping and handling instrument and said main body of said resurfacing prosthesis and suitable to connect them; a coupler which secures said connecting body to said main body, said coupler comprising: a plurality of bonding elements adapted to be interlocked, in an irremovable manner, in respective recesses provided in said connecting body; and a shear releaser, interposed between said main body of said resurfacing prosthesis and said connecting body, adapted to detach said connecting body from said main body. Other aspects are described and claimed. |
US11253374B2 |
Percutaneous bone graft delivery system and method
A bone graft delivery system includes a bone graft injector and an access portal. The access portal may include a handle having a first arm pivotably connected to, and biased away from, a second arm. A ratchet including a pawl may extend from the second arm. A delivery tube may be configured to mate with the first arm and be configured to store a bone graft material therein. A plunger including a shaft and a plunger tip at the distal end thereof may be configured to move through the delivery tube. At least a portion of the shaft may include teeth, the pawl of the ratchet being configured to iteratively contact the teeth. A user may hold the access portal with a first hand and the bone graft injector with a second hand, iteratively squeezing the handle to iteratively eject amounts of bone graft material into a patient. |
US11253373B2 |
Limited profile intervertebral implant with incorporated fastening and locking mechanism
In some embodiments, an intervertebral implant may include a body including a superior and an inferior surface. The implant may include a first channel extending from an anterior end towards the posterior end of the body. The implant may include a first anchor channel. The implant may include a first guide member positionable in the first channel. The implant may include a first anchor. When the first guide member moves from a first position to a second position the first anchor may be conveyed through the first anchor channel and couple the body to an adjacent vertebra. In some embodiments, the implant may include a first locking mechanism which inhibits, during use, the first guide member from moving from the second position to the first position upon activation of the first locking mechanism. |
US11253372B2 |
Universally expanding cages
An expandable medical implant that includes a lower lifting plate, an upper lifting plat, a distal lifting block, a proximal lifting block, a rotational block, a lifting screw, and a locking nut, and related methods of use. Also, an expandable medical implant that includes a lower lifting plate having a proximal lower angled lifting portion, an upper lifting plate having a proximal upper angled lifting portion, a center fork block, a lifting lobe, a distal screw, and a proximal nut, and related methods of use. |
US11253371B2 |
Vertebral body shaver assembly
A vertebral body shaver assembly may include a shaver inserter and a shaver instrument. The shaver inserter may be used to insert the shaver instrument into an intradiscal space between vertebral body endplates in a non-expanded condition with a footprint area A1. The shaver instrument may then be adjusted into a to an expanded condition with a footprint area A2that is greater than footprint area A1. As the shaver instrument is adjusted into the expanded condition, at least one blade may shave osteochondral material off at least one of the first vertebral body endplates. |
US11253365B2 |
Pneumatic or hydraulic cardiac assist devices
The embodiments relate to cardiac assist devices that comprise a jacket that wraps the exterior of the heart, where the jacket comprises one or more pneumatic or hydraulic bladders. The pneumatic or hydraulic bladders are linked to a pump, and the pump fills the bladders with fluid and withdraws the fluid in a cycle to match beats of the heart to assist contraction and pumping of the heart in systole or to assist expansion and filling of the heart in diastole. |
US11253363B2 |
Heart valve prosthesis
The present disclosure relates to heart valve prostheses, delivery devices, actuation handles, and other improved devices and methods that facilitate delivery of a heart valve prosthesis to a defective native valve structure in a patient, such as the aortic valve. |
US11253361B2 |
Heart valve pinch devices and delivery systems
Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. The two elements can clamp/pinch the heart valve leaflets to hold the prosthetic heart valve in place. The pinch device can have a flexible, expandable annular frame. A combined delivery system can deliver the pinch device and prosthetic heart valve with just a single access point and aid more accurate coaxial deployment. The pinch device can be mounted near distal end of an access sheath, and a catheter for delivering the prosthetic heart valve can be passed through a lumen of the same access sheath. |
US11253356B2 |
Methods and apparatus for percutaneous aortic valve replacement
A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve including a reversibly expandable occluder surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluder is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The stent(s) displace the native tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the stent(s) at the aortic annulus with precision and relative ease. |
US11253354B2 |
Apparatus and methods for anterior valve leaflet management
In some embodiments, a method includes delivering to a native valve annulus (e.g., a native mitral valve annulus) of a heart a prosthetic heart valve having a body expandable from a collapsed, delivery configuration to an expanded, deployed configuration. The method can further include, after the delivering, causing the prosthetic heart valve to move from the delivery configuration to the deployed configuration. With the prosthetic heart valve in its deployed configuration, an anchor can be delivered and secured to at least one of a fibrous trigone of the heart or an anterior native leaflet of the native valve. With the prosthetic heart valve disposed in the native valve annulus and in its deployed configuration, an anchoring tether can extending from the anchor can be secured to a wall of the heart to urge the anterior native leaflet towards the body of the prosthetic heart valve. |
US11253351B2 |
Apparatus for use in a surgical procedure
A tapered sleeve is provided that includes a lubricating coating on an inner surface. An implant (e.g., a pre-filled silicon breast implant) is introduced into a large end of the sleeve and extruded into a surgical pocket of minimal access incision size through a small-sized end of the apparatus. |
US11253346B2 |
Apparatus and method for a single sensor action plate
A vaccination device can be used to vaccinate day-old chicks. To vaccinate the day-old chicks safely while ensuring vaccination efficacy, the vaccination device can include a vaccination needle configured to extend from the vaccination device at a vaccination delivery location and an action plate. The action plate can be coupled to the vaccination device such that the action plate is positioned next to the vaccination delivery location. The action plate can include an action button, wherein the action button is configured to receive a day-old chick presented to the action plate in a predetermined loading position, receive a press of the action button, and in response to pressing the action button, cause the vaccination needle to extend from the vaccination device at the vaccination delivery location to deliver a subcutaneous injection to the day-old chick. |
US11253345B2 |
Methods for integrating scans including 3D cone beam scan for positioning of implant and fabrication of dental prosthesis
Methods for taking a scan of a patient's oral cavity for use in fabricating a dental prosthesis. Such methods may include providing a healing cap configured to be received within a subgingival void of a given tooth position, taking a first scan of the healing cap, wherein the first scan is taken outside of a patient's oral cavity, seating the healing cap, taking a second scan, which is an intraoral scan of the healing cap and surrounding surfaces once the healing cap is seated, taken inside the patient's oral cavity; and integrating the first scan of the healing cap with the intraoral second scan of the healing cap and the surrounding surfaces into an overall oral cavity scan. A third scan, (e.g., 3D cone beam scan), can also be taken, which is overlaid or otherwise integrated with the first and second scans, for use in fabrication of a dental prosthesis. |
US11253335B2 |
Lighting devices for attachment to a handheld electrosurgical instrument
A cordless, battery powered lighting device is disclosed which is configured to be removably installed on a distal end portion of a handheld electrosurgical instrument, and once the lighting device is installed on the distal end portion of the instrument, light automatically projects from the lighting device along the longitudinal axis of the surgical instrument. |
US11253333B2 |
Devices for surgical navigation systems
Trajectory frame assemblies for image guided surgical systems have a trajectory frame with a support column that can removably secure different components such as a tracking probe and an MER driver adapter to define and/or follow a desired intrabody trajectory. The trajectory frame assemblies include fins attached to the column support and a platform optionally with an X-Y table and/or arcuate reference brackets that are attached to the trajectory frame assemblies and can hold a reference frame with fiducials. |
US11253330B2 |
Systems and tools for use with surgical robotic manipulators
A tool for use with a surgical robotic manipulator that comprises an energy applicator including a shaft extending along an axis between a proximal end and a distal end. The shaft has a retention surface and an ejection surface. A tool assembly comprises a support structure to support the energy applicator and an axial connector assembly arranged to engage and releasably lock the energy applicator to the support structure in a locked state via the retention surface. The tool assembly is also configured to apply an ejection force to the energy applicator to provide a tactile indication to the user that the energy applicator is not fully engaged by the axial connector assembly if a suitable force is not provided by the user to overcome the ejection force and place the energy applicator in the locked state. |
US11253328B2 |
Articulation assembly for a surgical instrument such as for use in a robotic surgical system and methods of assembling the same
A surgical instrument articulation assembly includes a lead screw sub-assembly including four lead screws. A first gear sub-assembly includes first and second gears coupled to the first and third lead screws. A second gear sub-assembly includes third and fourth gears coupled to the second and fourth lead screws, respectively, a first compound gear including a distal gear coupling the first and second gears with one another, and a proximal gear coupled with a first coupling gear disposed about a first input. The third gear sub-assembly includes a second compound gear including a distal gear coupling the third and fourth gears with one another, and a proximal gear coupled with a second coupling gear disposed about a second input. A rotational input provided to the first or second input respectively rotates the first and third lead screws and or the second and fourth lead screws. |
US11253327B2 |
Systems and methods for automatically changing an end-effector on a surgical robot
Devices, systems, and methods for automatically exchanging a first end-effector on a robot arm with a second end-effector housed in a docking station. The first end-effector has a clamp that either engages or disengages the robot arm based upon an application of force of the robot arm onto the end-effector. The clamp has a spring loaded clip that disengages the first end-effector to allow the robot arm to move away from the released first end-effector. The robot arm is configured to automatically move to a port of a docking station housing the desired second end-effector using magnetic coils on the robot arm and the docking station to guide the robot arm. |
US11253322B2 |
Fluoro-navigation system for navigating a tool relative to a medical image
A fluoro-navigation system for navigating a tool relative to a medical image. The system includes a motorized X-ray imaging system for acquiring a plurality of images of a region of interest of a patient, the position of each image being known. Also included is a localization system, a registration phantom with a plurality of radiopaque fiducials, a tracker for being tracked by the localization system, a processor for receiving the plurality of images and for reconstructing a 3D medical image from the images using radiopaque fiducials visible in the plurality of images. Also included is base made of a substantially radiotransparent material, to be rigidly secured to a patient's bone and having a reproducible fixation system for attaching the registration phantom and/or tracker. |
US11253317B2 |
Soft tissue selective ablation surgical systems
A laser can produce pulses of light energy for tissue-type selective ejection of a volume of the target tissue, and the energy can be delivered to a treatment site through a waveguide, such as a fiber optic waveguide. The incident laser energy can be absorbed within a volume of the target tissue with a tissue penetration depth and pulse direction such that the propagation of the energy from the tissue volume is inhibited and such that the target tissue within the volume reaches the spinodal threshold of decomposition and ejects the volume, for example without substantial damage to tissue adjacent the ejected volume. The pulses are set to be tissue selective. |
US11253310B2 |
Gas-enhanced electrosurgical generator
A gas-enhanced electrosurgical generator. The gas-enhanced generator has a housing, a first gas control module in the housing and configured to control flow of a first gas, a second gas control module in the housing and configured to control flow of a second gas, a high frequency power module, and a controller, processor or CPU within the housing and configured to control the first gas control module, the second gas control module and the high frequency power module. The first gas and second gas may be any of CO2, argon and helium or another gas. The gas-enhanced electrosurgical generator may have a third gas control module in the housing and configured to control flow of a third gas and a third connector secured on an exterior of the housing. |
US11253309B2 |
Surgical tools for spinal facet therapy to alleviate pain and related methods
Methods and surgical tools for treating back pain use a spinal facet debridement tool with cautery and denuding action and minimally invasive protocol that can denude and cauterize soft tissue associated with a synovial capsule of the spinal facet joint. |