| Document | Document Title |
|---|---|
| US11078563B2 |
TiAl alloy and method of manufacturing the same
A TiAl alloy for forging, contains 41 at % or more and 44 at % or less of Al, 4 at % or more and 6 at % or less of Nb, 4 at % or more and 6 at % or less of V, 0.1 at % or more and 1 at % or less of B, and the balance being Ti and inevitable impurities. |
| US11078561B2 |
Soft magnetic material and method for producing the same
There are provided a soft magnetic material having a high saturation magnetization and a low coercive force and excellent in thermal endurance, and a method for producing the same. The present disclosure relates to a soft magnetic material represented by the following composition formula: Fe100-x-yBxNiy, wherein x satisfies 10≤x≤16 in at %, and y satisfies 0 |
| US11078560B2 |
System and method for applying amorphous metal coatings on surfaces for the reduction of friction
An embodiment relates to a composition comprising an amorphous alloy having a low coefficient of friction (COF) of 0.15 or less, wherein the amorphous alloy is substantially free of phosphor (P) and substantially free of boron (B). An embodiment relates to a method comprising solidifying a molten layer of an amorphous feedstock on a preexisting layer by controlling a heating source and a cooling rate so as to avoid formation of crystals in the molten layer and not affect a crystalline structure of the preexisting layer, and forming a specimen; wherein, the at least a portion specimen has the low COF. Another embodiment relates to a system comprising a drill string, wherein the drill string comprises a drilling bit and a drill pipe connected thereto, wherein at least a portion of the drill pipe comprises a coating having the low COF. |
| US11078557B2 |
Systems and methods for alkaline earth production
Hydrometallurgical systems, methods, and compositions are described in which amine-based lixiviants are utilized in substoichiometric amounts to recover alkaline earths from raw or waste materials. The lixiviant can be regenerated and recycled for use in subsequent iterations of the process or returned to a reactor in a continuous process. Extraction of the alkaline earth from the raw material and precipitation of the extracted alkaline earth is performed in the same reactor and essentially simultaneously. |
| US11078556B2 |
Method for production of a composite material using excess oxidant
A method of producing a composite material comprising: supplying a metal compound (MPC) of a product metal (MP) and a reductant (R) capable of reducing the metal compound (MPC) of the product metal (MP) to a reactor; forming a composite material comprising a matrix of oxidised reductant (R0) of the reductant (R), the product metal (MP) dispersed in the matrix of oxidised reductant (R0), and at least one of (i) one or more metal compounds (MPCR) of the metal compound (MPC) in one or more oxidation states and (ii) the reductant (R); and recovering the composite material from the reactor, wherein the metal compound (MPC) of the product metal (MP) is fed to the reactor such that it is in excess relative to the reductant (R). |
| US11078553B2 |
Method and device for the heat treatment of a metal component
Disclosed are implementations for heat treatment of a metal component, and a use of a furnace for heating a metal component. The implementations can be used in the partial hardening of optionally pre-coated components made of a high-strength manganese-boron steel. An example method for heat treatment of a metal component comprises at least the following steps: a) heating the component in a first furnace; b) moving the component into a temperature control station; c) cooling at least one first sub-region of the component in the temperature control station, wherein a temperature difference is set between the at least one first sub-region and at least one second sub-region of the component; d) moving the component from the temperature control station into a second furnace; and e) heating at least the at least one first sub-region of the component in the second furnace by at least 200 K. |
| US11078551B2 |
Three-dimensional cooling type hot-stamping method and system and vehicle structural member manufactured by the same
A hot-stamping method may include a three-dimensional cooling mode in which, when a closed-section product placed in an upper mold and a lower mold that are coupled each other is heat-treated under control of a controller, an external cooling water direct spraying operation of directly spraying cooling water onto an external portion of the closed-section product is performed and, simultaneously, an internal cooling water direct spraying operation of directly spraying cooling water into an internal of the closed-section product is performed. |
| US11078549B2 |
Reduction gas extraction from saturated top gas
The invention relates to a method for reducing metal oxides to metallized material by means of contact with reduction gas, wherein an accumulated top gas is dry dedusted and reformed in a raw gas mixture together with gaseous hydrocarbons. The water vapor content of the dry dedusted top gas designated for the preparation of the raw gas mixture is adjusted in a saturator in the countercurrent by means of saturation water, wherein the temperature of the saturation water is adjusted, by mixing cold water with a hot water having a higher temperature than the cold water, in order to produce the saturation water at a target value. The invention further relates to a device for carrying out such a method, having corresponding conduits. |
| US11078545B2 |
Detection of bacterial (Mollicutes) contamination
The present disclosure provides a method and system for the PCR amplification of a target sequence which suppresses non-specific amplification products. The disclosure concerns the use of a primer pair optimized to amplify a nucleic acid of a contaminant in the background of genomic DNA of a first organism. When DNA from a second organism suspected for comprising the contaminant is subjected to the same PCR-based amplification reaction, detection sensitivity and specificity of the contaminant is enhanced when an amount of genomic DNA of the first organism is present in the amplification reaction. |
| US11078539B2 |
Detecting colorectal neoplasm
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer. |
| US11078538B2 |
Post-treatment breast cancer prognosis
The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to extended treatment and cancer-free survival in a patient. In particular, the disclosure includes the identities of genes that are expressed in correlation with benefit in a switch in endocrine therapy used to treat a patient. The levels of gene expression are disclosed as a molecular index for predicting clinical outcome, and so prognosis, for the patient. The disclosure further includes methods for predicting cancer recurrence, and/or predicting occurrence of metastatic cancer, after initial treatment with an anti-estrogen agent. The disclosure further includes methods for determining or selecting the treatment of a subject based upon the likelihood of life expectancy, cancer recurrence, and/or cancer metastasis. |
| US11078535B2 |
Presymptomatic micro RNA targets for treatment of neurodegeneration pathology
Compositions and methods are provided for the early detection of neuroinflammation in a patient in a presymptomatic stage of a neurodegenerative disease. The method comprises identifying patients with elevated expression levels of a micro RNA selected from the group consisting of miR142-3p, miR142-5p, miR181a, miR181b, miR219-3p and miR219-5p. The identified patients can then be treated with a therapeutic pharmaceutical composition comprising antimiR oligonucleotides. |
| US11078534B2 |
Photocleavable nucleotide reagents with high stability
The present invention provides for stable nucleotide reagents used for nucleic acid amplification by PCR and RT-PCR (Reverse Transcriptase-PCR) that comprises modified nucleoside triphosphates. The present invention also provides for methods for using the modified nucleoside triphosphates for detecting the presence or absence of a target nucleic acid sequence in a sample in an amplification reaction. |
| US11078527B2 |
Method for quantifying and/or detecting human male DNA
According to a first aspect of the present invention, a method is provided for detecting and/or quantifying male genomic DNA in a sample, wherein the method comprises the step of amplification of a multicopy locus within the human Y-chromosome (MCL-Y), wherein said locus shares at least 80% sequence identity to a sequence according to SEQ ID NO. 3 over a stretch of at least 60 base pairs (bp). A second aspect of the present invention relates to a primer or primer pair which hybridizes under stringent conditions to a sequence according to SEQ ID NO. 3 and/or any of 4 to 11. The invention also relates to a kit. |
| US11078523B2 |
Processing particle-containing samples
A microfluidic device includes an input port for inputting a particle-containing liquidic samples into the device, a retention member, and a pressure actuator. The retention member is in communication with the input port and is configured to spatially separate particles of the particle-containing liquidic sample from a first portion of the liquid of the particle containing fluidic sample. The pressure actuator recombines at least some of the separated particles with a subset of the first portion of the liquid separated from the particles. The device can also include a lysing chamber that receives the particles and liquid from the retention member. The lysing chamber thermally lyses the particles to release contents thereof. |
| US11078521B2 |
Stabilization of nucleic acids on paper
The present invention and embodiments thereof relates to compositions and methods for storage, stabilization and preservation of biological samples and/or nucleic acids on a solid matrix. Methods for extracting, collecting, and recovering the biological samples and/or nucleic acids from the solid matrix are also described. |
| US11078519B2 |
Bioluminescent assays utilising secreted luciferases
Disclosed herein are methods for determining the amount or activity of one or more luciferases and methods for measuring the luminescent signal generated by one or more luciferases in a sample, the methods comprising incubating the sample with a reactive substrate(s) of the luciferase(s) to be analysed and a reducing agent to inactivate a first luciferase, wherein the first luciferase, in its native form, is a secreted luciferase. |
| US11078518B2 |
Method for evaluating blood coagulation reaction
Various methods for evaluating hemostatic effect and various blood coagulation initiation reagents were studied to construct a method for evaluating blood coagulation reaction mediated by a substance having an activity of substituting for coagulation factor VIII (FVIII). As a result, it was discovered that by using a coagulation initiation reagent containing activated coagulation factor XI (FXIa) and phospholipids, the effect of a substance having an activity of substituting for coagulation factor VIII (FVIII) on blood coagulation reaction can be evaluated using the amount of thrombin generated in the blood sample as an indicator. |
| US11078517B2 |
Hemoglobin A1c measurement method and measurement kit
This invention provides an amadoriase that acts on the β-chain of hemoglobin A1c (HbA1c) and generates hydrogen peroxide, a method for measurement of HbA1c using such amadoriase, and a reagent kit for measurement of HbA1c using such amadoriase. The method for measurement of HbA1c involves the use of an amadoriase that has specific activity of 0.1 U/mg or greater to αF6P and oxidizes the HbA1c β-chain amino terminus so as to generate hydrogen peroxide, and the reagent kit for measurement of HbA1c comprises such amadoriase. The method and the kit for measurement of HbA1c enable quantification of HbA1c to be performed rapidly, simply, and accurately. |
| US11078514B2 |
Fast detection of the presence of a target microbe in a liquid sample
A system is provided that includes a tray having a number of compartments for holding liquid samples and partitioning the liquid samples from one another. The liquid samples are prepared by adding an indicator configured to produce a characteristic change in light from the liquid samples when a target microbe metabolizes the indicator while the liquid samples are incubated. The system also includes a light sensor for sensing light from the liquid samples held in the tray while the plurality of liquid samples is incubated. The system further includes a processor coupled with the light sensor and configured to analyze the light from the liquid samples while the liquid samples are incubated to detect the characteristic change in light from one or more of the liquid samples if the target microbe is present in the liquid samples. |
| US11078513B2 |
Enzyme stabilization in electrochemical sensors
The present invention relates to a composition for forming an electrode, an electrochemical sensor comprising the same, and a method for determining an analyte using the electrochemical sensor. |
| US11078510B2 |
Methods for producing polypeptides in protease-deficient mutants of Trichoderma
The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants. |
| US11078507B2 |
Probability-directed isolation of nucleotide sequences (PINS)
The present invention pertains to an in vitro method in which the frequency of the targeted nucleotide sequence containing the DNA fragment of interest is increased stepwise, by several rounds of 1) dilution of a sample containing the DNA fragment of interest into several replicates (separation), 2) randomly amplifying DNA in the replicates (concentration), 3) detecting the DNA fragment of interest in at least one of the diluted and amplified replicates (selection) and repeating steps 1) through 3) until the DNA fragment of interest can be sequenced by standard sequencing techniques. |
| US11078505B2 |
Transaminase biocatalysts
The present disclosure relates to polypeptides having transaminase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides. |
| US11078501B2 |
Methods of fermenting mixtures that include di- and tri-saccharides formed at low temperature using a maltophilic yeast
Disclosed herein are materials and methods for the production of high concentrations of ethanol from plant starch material broken down into disaccharide and trisaccharide sugars such as maltose, isomaltose, and maltotriose from uncooked starch. Herein is also described use of a yeast strain capable of fermenting high maltose syrups into ethanol without the need to convert disaccharides or trisaccharides into glucose using exogenous glucoamylases. |
| US11078500B2 |
Method for the simultaneous production of ethanol and a fermented, solid product
The invention relates to a method for the simultaneous production of a fermented, solid product and ethanol comprising the following steps: 1) providing a mixture of milled or flaked or otherwise disintegrated biomass, comprising oligosaccharides and/or polysaccharides and live yeast in a dry matter ratio of from 2:1 to 100:1, and water; 2) fermenting the mixture resulting from step (1) under conditions where the water content in the initial mixture does not exceed 65% by weight, for 1-36 hours at a temperature of about 25-60° C. under anaerobic conditions; 3) incubating the fermented mixture resulting from step (2) for 0.5-240 minutes at a temperature of about 70-150° C.; and 4) separating wet fermented, solid product from the fermented mixture resulting from step (3); further comprising either a) that the fermentation in step (2) is performed in one or more interconnected paddle worm or continuous worm conveyers with inlet means for the fermentation mixture and additives and outlet means for the ferment as well as control means for rotation speed, temperature and pH, or b) that one or more processing aids are added in any of steps (1), (2) and (3) and further comprising a step of 5) separating crude ethanol from the fermented mixture in step (2) by vacuum and/or in step (3) by vacuum or by injection of steam and condensing the surplus stripping steam. The invention further relates to the products of this method as well as uses thereof. |
| US11078499B2 |
Host cells and methods for producing toluene biochemically
The present invention provides for a genetically modified host cell comprising a first polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase, and having an enzymatic activity to decarboxylate a phenylacetic acid into a toluene and a carbon dioxide, and a second polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase activating enzyme, and having an enzymatic activity to cleave a S-adenosylmethionine (SAM) to form a methionine and a 5′-deoxyadenosyl radical. |
| US11078496B2 |
System for F-box hormone receptor regulated protein expression in mammalian cells
The present invention relates to a system for F-box hormone receptor regulated protein expression in mammalian cells. The system includes a silencing nucleic acid molecule comprising a first promoter and an shRNA operably linked to the first promoter, where the shRNA silences expression of a target protein. The system also includes an expression nucleic acid molecule comprising a second promoter, an F-box hormone receptor operably linked to the second promoter, and a nucleic acid molecule encoding a fusion protein comprising a degron fused to the target protein, where the nucleic acid molecule encoding the fusion protein is operably linked to the second promoter. Also disclosed are vectors comprising the system of the present application and methods of use thereof. |
| US11078495B2 |
Methods and compositions for integration defective lentiviral vectors
The present invention provides an integration-defective lentiviral vector based on a parental lentivirus and related methods, the integration-defective lentiviral vector including one or more of the following: (a) a mutation, deletion or other modification of one or more binding sites for a host factor involved in gene silencing; (b) an addition of one or more binding sites for a transcription activator, which can be natural (such as but not limited to ubiquitous and/or tissue/cell type specific) including but not limited to SP1 NFkB, or synthetic including but not limited to binding sites for tetracycline regulated trans activators tTA, rtTA, tT65, and/or rtT65; (c) one or more nucleic acid sequences from a SV40 genome, wherein the one or more sequences are obtained from a region of the SV40 genome upstream to the SV40 poly-adenylation signal; (d) a shRNA expression cassette, which encodes a shRNA directed to a host gene involved in epigenetic silencing and/or in DNA repair pathways; or (e) any combination of (a), (b), (c) and (d), wherein as compared to the parental lentivirus, the integration-defective lentiviral vector resists gene silencing. |
| US11078494B2 |
Vector for targeting the human Rosa26 gene
The invention provides a method for generating a transgenic eukaryotic cell population having a modified human Rosa26 locus, which method includes introducing a functional DNA sequence into the human Rosa26 locus of starting eukaryotic cells. Also provided are targeting vectors useful in the method, as well as a cell population and a transgenic non-human animal comprising a modified human Rosa26 locus. Finally, the invention provides an isolated DNA sequence corresponding to the human Rosa26 locus. |
| US11078492B2 |
Isolated polynucleotides and polypeptides, and methods of using same for increasing nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and/or abiotic stress tolerance
Provided are methods of increasing nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence at least 80% identical to SEQ ID NO: 387, 1-386, 388-469, 763-3704 and 3705; or an exogenous polynucleotide encoding a polypeptide at least 80% identical to SEQ ID NO: 602, 470-601, 603-762, 3706-5858, 5860-5910, 5912, 5914-5923, 5925-6046 or 6047. Also provided is an isolated polynucleotide comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOs: 387, 1-386, 388-469, 763-3704 and 3705, which can be used to increase the nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant. |
| US11078491B2 |
Vaccines against Zika virus based on Zika structure proteins
Compositions including a virus-like particle (VLP)-based vaccine displaying a portion of ZIKV envelope protein (E) domain III (DIII) and a portion of ZIKV envelope protein (E) and related methods are disclosed herein. Further, compositions including vaccines comprising a portion of ZIKA virus E protein, wherein the portion of ZIKA virus E protein is either a full-length version of ZIKA virus E protein or a functionally equivalent version of the full-length ZIKA virus E protein, are disclosed. |
| US11078490B2 |
Optimized vector for delivery in microbial populations
The present invention relates to a vector, preferably included in a delivery vehicle, comprising no more than 100, preferably no more than 10, restriction sites recognized by the restriction enzymes encoded by each bacterium of a group of bacteria of interest. The invention also relates to the use of said vector, preferably included in a delivery vehicle, as a drug, especially in the treatment of a disease in a patient in need thereof. |
| US11078488B2 |
Fibrotic treatment
The present invention relates to compositions, methods and kits for the treatment of fibrosis. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment of cardiac fibrosis. The invention provides a method of treating fibrosis in an individual comprising administering an inhibitor of insulin-regulated aminopeptidase (IRAP), thereby treating fibrosis. |
| US11078486B2 |
Compounds and methods for reducing ATXN2 expression
Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of ATXN2 RNA in a cell or animal, and in certain instances reducing the amount of Ataxin-2 protein in a cell or animal. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom or hallmark of a neurodegenerative disease. Such symptoms and hallmarks include ataxia, neuropathy, and aggregate formation. Such neurodegenerative diseases include spinocerebellar ataxia type 2 (SCA2), amyotrophic lateral sclerosis (ALS), and parkinsonism. |
| US11078482B2 |
Duplex sequencing using direct repeat molecules
Described herein is a population of direct repeat molecules, where each molecule of the population contains a direct repeat composed of sequences that are amplified from the opposite strands of a double-stranded fragment of genomic DNA. Within each molecule, the first repeat (referred to as TOP) is amplified from the one strand of a double-stranded fragment of genomic DNA and the second repeat (referred to as BOT′) is amplified from the other strand of the same fragment of double-stranded fragment of genomic DNA. |
| US11078481B1 |
Methods for screening for cancer targets
This invention describes a novel CRISPR/Cas9 target identification platform permitting the discovery of novel genes and pathways involved in the ability of T cells and NK cells to react against and generate an anti-tumor response. |
| US11078480B2 |
High-throughput identification of intermolecular interactions
Methods of detecting an interaction between a macromolecule and an interaction partner are described. Kits are also described. |
| US11078477B2 |
Automated isolation and chemical reaction(s) of nucleic acids
The present teachings relate to methods, kits and devices for performing automated sequential nucleic acid isolation and conversion/purification in a single closed system. In various embodiments, the present teaching enable a user to (i) load a device with test samples, reagents and consumables; (ii) select or program the device for the desired nucleic acid isolation and subsequent chemical treatment and/or conversion reaction(s) without further user intervention; and recovering the isolated and treated and/or converted nucleic acid at the conclusion of the program once the device is activated. |
| US11078474B2 |
Method and device for non-thermal extraction of phytochemicals from macroalgae
A method is for the extraction of a phytochemical, e.g., peptide or protein, or a chemical element from a macroalgae, by applying pulsed electric field (PEF)- or continuous electric field (CEF)-treatment to the macroalgae in a solvent, under pressure higher than the ambient pressure. A device and system carry out this method. |
| US11078469B2 |
Evolution of TALENs
Engineered transcriptional activator-like effectors (TALEs) are versatile tools for genome manipulation with applications in research and clinical contexts. One current drawback of TALEs is that the 5′ nucleotide of the target is specific for thymine (T). TALE domains with alternative 5′ nucleotide specificities could expand the scope of DNA target sequences that can be bound by TALEs. Another drawback of TALEs is their tendency to bind and cleave off-target sequence, which hampers their clinical application and renders applications requiring high-fidelity binding unfeasible. This disclosure provides methods and strategies for the continuous evolution of proteins comprising DNA-binding domains, e.g., TALE domains. In some aspects, this disclosure provides methods and strategies for evolving such proteins under positive selection for a desired DNA-binding activity and/or under negative selection against one or more undesired (e.g., off-target) DNA-binding activities. Some aspects of this disclosure provide engineered TALE domains and TALEs comprising such engineered domains, e.g., TALE nucleases (TALENs), TALE transcriptional activators, TALE transcriptional repressors, and TALE epigenetic modification enzymes, with altered 5′ nucleotide specificities of target sequences. Engineered TALEs that target ATM with greater specificity are also provided. |
| US11078465B2 |
Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols
The present disclosure discloses an alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols, and belongs to the technical field of bioengineering. The alcohol dehydrogenase mutant of the present disclosure has excellent catalytic activity and stereoselectivity, and may efficiently catalyze the preparation of a series of chiral diaryl alcohols in R- and S-configurations. By coupling alcohol dehydrogenase of the present disclosure to glucose dehydrogenase or formate dehydrogenase, the synthesis of chiral diaryl alcohol intermediates of various antihistamines may be achieved. Compared with the prior art, a method for preparing diaryl chiral alcohols through asymmetric catalytic reduction using the alcohol dehydrogenase of the present disclosure has the advantages of simple and convenient operation, high substrate concentration, complete reaction and high product purity, and has great industrial application prospects. |
| US11078462B2 |
Perivascular stromal cells from primate pluripotent stem cells
The invention provides methods, compositions and kits for making and using pericyte-like cells or perivascular stromal cells derived from pPS cells. |
| US11078458B2 |
Genome-wide rationally-designed mutations leading to enhanced lysine production in E. coli
The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals. |
| US11078456B2 |
Fusarium solani and use of same in prevention and treatment of southern blight of Dendrobium officinale Kimura et Migo
A Fusarium solani strain and a use thereof in the control of southern blight disease of Dendrobium officinale Kimura et Migo, and the strain JSNL007-2 has been identified as Fusarium solani and has been deposited in China Center for Type Culture Collection on Mar. 10, 2017 with a deposit number of CGMCC NO. 13687. The Fusarium solani JSNL007-2 of the present invention has a significant effect on the disease resistance of Dendrobium officinale Kimura et Migo, especially for improving the ability of Dendrobium officinale Kimura et Migo to resist southern blight disease, and has a certain effect on reducing the use of chemical pesticides, which is an important means to ensure food safety. |
| US11078454B2 |
Bioreactor and method of forming complex three-dimensional tissue constructs
A bioreactor and method of forming complex three-dimensional tissue constructs in a single culture chamber. The bioreactor and methods may be used to form multi-phasic tissue constructs having tissue formed from multiple cell types in a single culture chamber. The bioreactor includes at least one translation mechanism to facilitate translation of one or more tissue constructs without direct user intervention, thereby providing a closed, sterile environment for complex tissue fabrication. The bioreactor may be used as a stand-alone device or as part of a large-scale system including many bioreactors. The large-scale system may include a perfusion system to monitor and regulate the tissue culture environment. |
| US11078450B2 |
Material containing solid bleaching agent, and detergent composition
A stabilized solid bleaching agent which has good solubility in water without undergoing the occurrence of foaming and without generating residues has been demanded. The present invention provides a stabilized solid-bleaching-agent-containing material having a coating layer formed therein, wherein the coating layer contains at least one component selected from the group consisting of an alkali metal salt of an aromatic carboxylic acid, an alkali metal salt of a non-cyclic dicarboxylic acid, an alkali metal salt of a non-cyclic monocarboxylic acid having 1 to 7 carbon atoms and mixtures thereof. |
| US11078448B2 |
Detergent composition containing a fluorinated solvent for dry cleaning
A detergent composition for dry cleaning is disclosed. The detergent composition for dry cleaning includes a) 5 to 10% by weight of a fluorinated (fluoro-based) solvent, b) 1 to 2% by weight of a cleaning booster, c) 5 to 10% by weight of an anti-shrinkage agent, d) 40 to 50% by weight of a water-soluble solvent, and e) 30 to 40% by weight of water. |
| US11078444B2 |
Laundry composition
A composition comprising a plurality of particles, wherein said particles comprise: a) 10 to 60 w.t. % polyethylene glycol, wherein the polyethylene glycol has a weight average molecular weight from 4000 to 12000; b) 0.1 to 50 w.t. % polysaccharide; c) 0.1 to 50 w.t. % ethoxylated non-ionic surfactant having a general formula: R1O(R2O)xH R1=a saturated fatty alcohol or polypropylene glycol. R2=C2H4 or mixture of C2H4 and C3H6x=8 to 120 and having a melting point between 40 and 60° C.; and d) 0.1 to 30 w.t. % perfume materials. |
| US11078442B2 |
Method and test kit for recreation of an odor
Suggested is a method for the extraction of fragrances from natural starting material consisting of the following steps: (a) providing a sample of the natural starting material in a pressure proof sample container; (b) bringing in the sample in contact with liquefied petroleum gas of propane and/or butane gas, preferably; (c) extracting the fragrances from the natural starting material provided in step (b); (d) venting of the pressure proof sample container, while the liquefied petroleum gas is evaporated and the fragrances is maintained as residue in the container; and optionally (e) dissolving the fragrances in a suitable solvent. |
| US11078439B2 |
Paste type lubrication
In a paste type lubrication between a steel wire rope and a rope groove of a pulley, is applied a paste lubricant which contains oil and small solid particles. Solid particles could be of a wide variety sizes and they are small enough to at least partly fit into the valleys between the peaks of surface roughness of the ropes or the rope groove. |
| US11078438B2 |
Extreme pressure metal sulfonate grease
An overbased metal detergent grease comprising at least one of polyalkylene glycol and/or an acid having at least one of both a nitrogen and a sulfur atom. The grease has improved extreme pressure performance as measured by the Standard Test Method for Measurement of Extreme-Pressure Properties of Lubricating Grease (Four-Ball Method), ASTM D2596.Methods of making an overbased metal detergent grease comprising using at least one of polyalkylene glycol and/or an acid having at least one of both a nitrogen and a sulfur atom. Methods of lubricating mechanical components using the grease comprising contacting the mechanical component with the grease. Mechanical components can include gears, drivetrain elements, bearings, hinges, or combinations thereof. |
| US11078430B2 |
Haze-free base oils with high paraffinic content
The present invention relates to a method for reducing the cloud point of a base oil with high saturates/paraffinic content to below 0° C., wherein the method comprises subjecting said base oils to a cloud point reduction step comprising adding said base oil to a solvent mixture, wherein the solvent mixture comprises a paraffin naphtha fraction and a co-solvent to obtain a solvent treatment mixture; and subjecting the solvent treatment mixture to a solvent de-waxing step. |
| US11078428B2 |
Generating a soft sensor for crude stabilization in the petroleum industry
A global theoretical graphical representation of a soft sensor is generated based on a cursory model, where the soft sensor is used to control crude stabilization. A plurality of local real-life graphical representations are generated for the soft sensor, each of the plurality of local real-life graphical representations corresponding to a respective local regime. A global real-life graphical representation is generated for the soft sensor by combining the plurality of local real-life graphical representations. A set of numerical values for the soft sensor are generated based on the global real-life graphical representation. The soft sensor is updated based on lab results and a crude stabilization operation is controlled using the soft sensor. |
| US11078426B2 |
Methods, systems, and devices for liquid hydrocarbon fuel production, hydrocarbon chemical production, and aerosol capture
Methods, systems, and devices for liquid hydrocarbon fuel production, hydrocarbon chemical production, and aerosol capture are provided. For example, a carbon-oxygen-hydrogen (C—O—H) compound may be heated to a temperature of at least 800 degrees Celsius such that the C—O—H compound reacts through a non-oxidation reaction to generate at least a hydrocarbon compound that may be at least a component of a liquid hydrocarbon fuel or a hydrocarbon chemical. The liquid hydrocarbon fuel may be a liquid when at a temperature of 20 degrees Celsius. The C—O—H compound may include biomass. In some cases, the hydrocarbon compound produced through the non-oxidation reaction includes a hydrocarbon aerosol form as the hydrocarbon compound at least as it is produced or cools. Some embodiments include aerosol capture methods, systems, and devices, which may include passing a hydrocarbon aerosol form through a material in a liquid phase in order to gather the aerosol material. |
| US11078425B2 |
Resveratrol-based flame retardant materials
A process of forming a resveratrol-based flame retardant small molecule with a phosphonate/phosphinate molecule that includes a chloride group and a terminal functional group. |
| US11078423B2 |
Liquid crystal display device
The present invention relates to a liquid crystal display device. The liquid crystal display device of the present invention comprises a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein said first substrate and said second substrate are disposed in parallel and opposite to each other, with the distance between said first substrate and said second substrate being 2.5 μm to 3.2 μm; alignment layers are disposed on the sides of said first and second substrates that are close to said liquid crystal composition; and said alignment layers are provided with vertical alignment films that allow liquid crystal molecules in said liquid crystal composition to be arranged roughly perpendicular to said first or second substrate. |
| US11078422B2 |
Liquid crystal display panel, method for manufacturing the same and liquid crystal composition
An LCD panel, comprises substrates facing each other, a liquid crystal layer disposed between the substrates and liquid crystal alignment layers, each sandwiched between the liquid crystal layer and a respective one of the substrates, wherein the liquid crystal alignment layers comprises hydrocarbon derivative having perfluorocarbon group. |
| US11078418B2 |
Corrosion inhibitors for fuels and lubricants
The present invention relates to novel uses of corrosion inhibitors in fuels and lubricants. |
| US11078413B2 |
Organic-inorganic hybrid perovskites, devices, and methods
Provided herein are organic-inorganic hybrid-perovskites, including metal halide perovskites having a 1D crystal structure. The metal halide perovskites may be luminescent. The metal halide perovskites may include a dopant, including an emitter dopant. Methods of forming metal halide perovskites, and devices including the metal halide perovskites also are provided. |
| US11078410B2 |
Modified reactive resin compositions and use thereof for coating propping agents
Coated proppants useful in fracking operations in oil and gas production are coated with a novolac resin containing a linear or cyclic organopolysiloxane of specific composition. The coatings are more fracture resistant, thus producing less fines during use, resulting in longer production campaigns. |
| US11078409B2 |
Electrically conductive proppant coating and related methods
An electrically conductive proppant coating and a method for applying the coating to the proppant, whereby the coated electrically conductive proppant can determine formation characteristics, such as dimensions, orientation, and conductivity. |
| US11078403B2 |
Synergistic sulfide scavenging additives for use in oilfield operations
Systems, compositions, and methods for synergistic additives for use in the scavenging of sulfur-containing compounds encountered in oilfield operations are provided. In one embodiment, the methods comprise injecting a sulfide scavenging additive that does not comprise a significant amount of an aldehyde into at least a portion of a subterranean formation where one or more sulfur-containing species are present; and injecting a synergistic additive comprising at least one base into at least the portion of the subterranean formation. |
| US11078402B2 |
Use of particulate or fibrous materials in gravel pack applications
Methods include drilling at least one interval of a wellbore with a water-based wellbore fluid producing a filtercake in the at least one interval of the wellbore. The methods also include gravel packing an interval of a wellbore traversing a subterranean formation with a gravel pack that comprises polyhydroxycarboxylic acid, and hydrolyzing the polyhydroxycarboxylic acid to degrade at least a portion of the filtercake. |
| US11078401B2 |
Rare earth oxide as a weighting and bridging agent
Methods of treating a subterranean formation and treatment fluids are discussed herein. The methods generally include treating the subterranean formation with a rare earth oxide by providing a first treatment fluid having a density of at least about 10 pounds per gallon including a rare earth oxide; and introducing the first treatment fluid into the subterranean formation. |
| US11078400B2 |
Accelerators for composite cement compositions
Disclosed herein are methods, compositions, and systems for cementing. A method of cementing may comprise: providing a composite cement composition comprising a pozzolan, an accelerator, and water, wherein the accelerator comprises a chloride salt and a sulfate salt, wherein the composite cement composition is free of Portland cement or comprises Portland cement in an amount of about 50% by weight of cementitious components or less; and allowing the composite cement composition to set. |
| US11078399B2 |
Dry blend pre-flush and spacer package and method for mixing and injecting a pre-flush and spacer on-the-fly to clean a subterranean well
The present invention relates to a dry blend one-part pre-flush and spacer package for forming a water-based pre-flush and spacer on-the-fly for use in a subterranean well and a method of mixing a pre-flush and spacer on-the-fly for use in a subterranean well. The dry blend pre-flush and spacer package includes an anionic surfactant, a builder compound, and optionally, a defoamer, a dispersant calcium chelator, a density modifying agent, a viscosifying agent such as a solid, and preferably rapidly hydrating, gellant, salt and one or more lost-circulation materials. The dry blend pre-flush and spacer package is mixed on-the-fly with water at the subterranean well site to form the pre-flush and spacer at a pre-selected density and the pre-flush and spacer, when pumped into the subterranean well by a pressure pumper, converts the well from an oil-wet or substantially non-water-wet condition to a substantially water-wet condition. |
| US11078396B2 |
Spacer fluid compositions, methods, and systems for aqueous based drilling mud removal
Spacer fluids include an emulsion, a surfactant package, and at least one additive that modifies the rheology of the spacer fluid, the density of the spacer fluid, or both. The emulsion may include an aqueous external phase and a hydrocarbon-based internal phase. The surfactant package may include one or more surfactants. The surfactant package may also include a surfactant having the general structure R—(OCH2CH2)9—OH, where R is a hydrocarbyl having 12 carbon atoms, 13 carbon atoms, or 14 carbon atoms. The spacer fluid may contain at least 4.25 pounds of R—(OCH2CH2)9—OH per barrel of the spacer fluid. |
| US11078395B2 |
Wellbore drilling compositions
Drilling mud compositions including a first concentration of powdered latex and a second concentration of SAS are described. The second concentration of SAS can be greater than or equal to the first concentration of latex. In some examples, the second concentration of SAS can be greater than the first concentration of latex. The drilling mud compositions may include an oil-based carrier, or a water-based carrier. An example technique includes dispersing a first predetermined amount of powdered latex and a second predetermined amount of SAS in a water-based carrier to form a water-based mud. Another example technique includes dispersing a first predetermined amount of powdered latex and a second predetermined amount of SAS in an oil-based carrier to form an oil-based mud. |
| US11078393B2 |
Non-toxic high-density fluid for completion applications
A modified high density brine for use in subterranean drilling and completion operations. The modified high density brine includes the addition of high density particle addition that can optionally be surface-modified. The resultant modified high density brine eliminates the need for toxic, corrosive, and costly ZrBr2 additions or other ionic additives to boost the density of the modified high density brine to 15-17 lbs./gallon or greater. |
| US11078389B2 |
Twist shut adhesive sealable trash liner
In the present invention, a solvent-based (SB) adhesive for the purpose of closing or sealing the open end of a bag, such as a plastic trash bag, liner or like, is coated to the exterior or interior surface of said bag and creates a neat, tight functional seal to said bag when twist activated. |
| US11078383B2 |
Adhesive articles permitting damage free removal
The present disclosure provides adhesive articles that can be removed from surfaces without damage by having reduced or eliminated contribution of a core backing to peel force generated by the adhesive during removal. In some instances, this can be accomplished by a core that loses structural integrity in a direction normal to a plane defined by a major surface. In other instances, the contribution is reduced by compromising the interface between the core and a peelable adhesive layer. |
| US11078381B2 |
Catechol-containing adhesive hydrogel, composition for preparing adhesive hydrogel, and compositions each including said adhesive hydrogel
A hydrogel that adheres to the surface of materials is provided by using as constituent elements a water-soluble main chain monomer, crosslinking agent, polymerization initiator, and adhesive monomer having at least a catechol group in a side chain. |
| US11078377B2 |
Actinic radiation cured polyurethane coating for decorative surface coverings
The present invention is related to decorative surface coverings, in particular floor or wall coverings, exhibiting low volatile organic compounds (VOC) emission, comprising one or more adjacent plasticized polyvinyl chloride layers and a polyurethane top-layer, said top-layer being obtained from radiation curing a 100% solids polyurethane formulation. |
| US11078374B2 |
Active-energy-ray-curable liquid composition, three-dimensional object forming material set, method for producing three-dimensional object, and three-dimensional object producing apparatus
Provided is an active-energy-ray-curable liquid composition containing a monomer (A) having a hydrogen-bonding capacity and a solvent (B) having a hydrogen-bonding capacity, wherein the active-energy-ray-curable liquid composition satisfies conditions below, |
| US11078372B2 |
Coating liquid and gas barrier laminate
A coating liquid includes: ultrafine zinc oxide particles; a polyester resin; an ammonium polycarboxylate salt; and water, in which an amount of the ammonium polycarboxylate salt is from 1 to 35 mass % with respect to that of the ultrafine zinc oxide particles. |
| US11078366B2 |
Bis-azo colorants for use as bluing agents
This invention relates to bis-azo colorants for use as bluing agents, laundry care compositions comprising bis-azo colorants that may serve as bluing agents, processes for making such bluing agents and laundry care compositions and methods of using the same. The bluing agents are generally comprised of at least two components: at least one chromophore component and at least one polymeric component. These bluing agents are advantageous in providing a whitening effect to fabrics, while not building up over time and causing undesirable blue discoloration to the treated fabrics. |
| US11078365B2 |
Formaldehyde-free wood binder
The formaldehyde-free binder for materials containing cellulose contains a hydroxy aldehyde resin polycondensed with an ammonium salt, the resin being obtained, in especially preferred embodiments, from glycerin, in situ, with the aid of hydrogen peroxide. A protein component consisting of animal blood is added. The binder is urea-free and can be used as a one-component or two-component binder. It binds materials such as wood, paper and other natural fibres to form high-quality composite material products. |
| US11078362B2 |
Polyamide composition containing a polyamide and an additive
The present invention relates to a polyamide composition (PC) which comprises at least one polyamide (P) and at least one additive (A). The present invention further relates to the use of the polyamide composition (PC) in a selective laser sintering process, in an injection molding process, for producing molded articles and in an extrusion process. |
| US11078360B2 |
Polycarbonate/polycarbonate-polysiloxane composition
A thermoplastic resin composition and a molded article formed using the same. The thermoplastic resin composition includes: a polycarbonate resin; a first polycarbonate-polysiloxane copolymer resin; a second polycarbonate-polysiloxane copolymer resin; and a glycol-modified polyester resin, wherein the first polycarbonate-polysiloxane copolymer resin includes a polysiloxane block having an average degree of polymerization of about 30 to about 45 and the second polycarbonate-polysiloxane copolymer resin includes a polysiloxane block having an average degree of polymerization of about 70 to about 100. The thermoplastic resin composition can have good properties in terms of transparency, impact resistance, chemical resistance, and/or hydrolysis resistance. |
| US11078357B2 |
Thermoplastic elastomer composition, extrusion molded article, and medical tube
An object of the present invention is to provide a thermoplastic elastomer composition capable of molding a medical tube excellent in the transparency and kink resistance. The present invention is related to a thermoplastic elastomer composition including a hydrogenated block copolymer (A) wherein the copolymer has at least two polymer blocks P composed mainly of an aromatic vinyl compound unit and at least one polymer block Q composed mainly of a conjugated diene compound unit; the total content of aromatic vinyl compound units is from 8 to 25% by mass; and the copolymer contains a high-MFR hydrogenated block copolymer and a propylene polymer (B). |
| US11078354B2 |
Fluoroelastomer compounds
The present invention is directed to compounds comprising a perfluoroelastomer and a blend of two different particle size carbon blacks that, when cured with a curing agent, comprise a heterocyclic or perfluorinated crosslink. Such compounds comprise copolymerized units of unsaturated fluorinated olefins, a perfluoro(vinyl ether), and a cure site fluorinated monomer having a nitrile cure site, plus a blend of carbon blacks. Articles cured from these compounds exhibit improved sealing force. |
| US11078352B2 |
Thermoplastic elastomer composition, use thereof, method for producing same, ethylene/α-olefin/unconjugated polyene copolymer and use thereof
[Problem] The purpose of the invention is to provide: a thermoplastic elastomer composition capable of providing molded articles that are lightweight, have better oil resistance than those provided by conventional cross-linked thermoplastic elastomers, and have hardness and mechanical properties such as tensile strength and tensile elongation that are equal to or superior to those provided by conventional cross-linked thermoplastic elastomers; and an ethylene/α-olefin/unconjugated polyene copolymer having little compression set at low temperature as well as flexibility and an excellent balance of rubber elasticity at low temperature and tensile strength at normal temperature.[Solution] Produced are: a thermoplastic elastomer composition obtained by dynamically crosslinking a mixture containing a crystalline olefin polymer (A), an ethylene/α-olefin (having 4-20 carbon atoms)/unconjugated polyene copolymer (1B) that satisfies specific requirements, and a phenol resin-based crosslinking agent (C); and an ethylene-α-olefin/unconjugated polyene copolymer (2B) that satisfies specific requirements. |
| US11078350B2 |
Cleaning member, production method of same, and image forming apparatus
Provided is a cleaning member including a urethane rubber, wherein the urethane rubber has a cyclic structure portion in which a fluorine atom is directly bonded to the cyclic structure portion. |
| US11078345B2 |
Pore inducer and porous abrasive form made using the same
Various embodiments disclosed relate to pore inducers and porous abrasive forms made using the same. In various embodiments, the present invention provides a method of forming a porous abrasive form including heating an abrasive composition including pore inducers to form the porous abrasive form. During the heating the pore inducers in the porous abrasive form reduce in volume to form induced pores in the porous abrasive form. |
| US11078342B2 |
Block expandable polymeric compositions
The present invention relates to an expandable polymeric composition that comprises: a) from 60% to 88% by weight of a vinyl aromatic polymer and/or copolymer, calculated respect to (a)+(b); b) from 12% to 40% by weight of a block copolymer, containing at least one vinyl aromatic polymer and/or copolymer and at least one hydrogenated diene polymer, calculated respect to (a)+(b); c) from 3 parts to 10 parts by weight of a blowing agent, calculated on 100 parts of (a)+(b). |
| US11078341B2 |
Thermoplastic polymers
Thermoplastic polymers, for example fluoropolymers, are foamed by use of a solid formulation comprising thermoplastic polymer and manganese oxalate. |
| US11078337B2 |
High-χ block copolymers for directed self-assembly
The present invention is broadly concerned with novel directed self-assembly compositions, processes utilizing those compositions, and the resulting structures that are formed. The composition comprises a block copolymer of polystyrene and a polymethylmethacrylate block with polylactic acid side chains (“PS-b-P(MMA-LA)”). The block copolymer is capable of crosslinking and micro-phase separating into lines and spaces measuring about 10-nm or smaller with sub-20 nm L0 capability. Additionally, PS-b-P(MMA-LA) can be thermally annealed without a top-coat for simpler processing than the prior art. The polylactic acid side chains also increase the etch rate of the poly(methylmethacrylate) block when exposed to oxygen plasma, as well as lower the Tg. |
| US11078333B2 |
Copolymerization of elemental sulfur to synthesize high sulfur content polymeric materials
Copolymerization of elemental sulfur with functional comonomers afford sulfur copolymers having a high molecular weight and high sulfur content. Nucleophilic activators initiate sulfur polymerizations at relative lower temperatures and in solutions, which enable the use of a wider range of comonomers, such as vinylics, styrenics, and non-homopolymerizing comonomers. Nucleophilic activators promote ring-opening reactions to generate linear polysulfide intermediates that copolymerize with comonomers. Dynamic sulfur-sulfur bonds enable re-processing or melt processing of the sulfur polymer. Chalcogenide-based copolymers have a refractive index of about 1.7-2.6 at a wavelength in a range of about 5000 nm-8μιτι. The sulfur copolymer can be a thermoplastic or a thermoset for use in elastomers, resins, lubricants, coatings, antioxidants, cathode materials for electrochemical cells, dental adhesives/restorations, and polymeric articles such as polymeric films and free-standing substrates. Optical substrates are constructed from the chalcogenide copolymer and are substantially transparent in the visible and infrared spectrum. |
| US11078332B2 |
Carbohydrate polyamine binders and materials made therewith
A binder comprising the products of a carbohydrate reactant and polyamine is disclosed. The binder is useful for consolidating loosely assembled matter, such as fibers. Uncured fibrous products comprising fibers in contact with a carbohydrate reactant and a polyamine are also disclosed. The binder composition may be cured to yield a fibrous product comprising fibers bound by a cross-linked polymer. Further disclosed are methods for binding fibers with the carbohydrate reactant and polyamine based binder. |
| US11078331B2 |
Acid neutralizing polymer materal and method of making same
A method of preparing an acid reactive functionalized polyamide includes preparing a first reaction product by contacting and reacting virgin polyamide fabric material with tert-butoxide in a first aliquot of a polar aprotic solvent and preparing a second reaction product by adding an amine to a second aliquot of the polar aprotic solvent. A third reaction product is prepared by mixing the first reaction product and the second reaction product where the third reaction product is the acid reactive functionalized polyamide. The preparation of each respective reaction product is for a period of time and at a temperature sufficient to produce the respective reaction product. |
| US11078320B2 |
Porous materials based on aromatic amines
The invention relates to a porous material comprising at least one polyfunctional isocyanate (a1) and at least one polyfunctional substituted aromatic amine (a2-s) of the general formula (I): where R1 and R2 are selected from among hydrogen and linear or branched alkyl groups having from 1 to 6 carbon atoms and all substituents Q1 to Q5 and Q1′ to Q5′ are selected from among hydrogen, a primary amino group and a linear or branched alkyl group having from 1 to 12 carbon atoms, where at least one of Q1, Q3 and Q5 and at least one of Q1′, Q3′ and Q5′ is a primary amino group and the compound has at least one linear or branched alkyl group having from 1 to 12 carbon atoms in the α position relative to at least one primary amino group bound to the aromatic ring in formula (I). |
| US11078318B2 |
Block copolymer
The present application may provide a block copolymer and a use thereof. The block copolymer of the present application has excellent self-assembly properties or phase separation characteristics, to which various functions to be required can also be freely imparted. |
| US11078316B2 |
Method for polymerization with external cooling
Higher throughput in aqueous addition polymerization is made possible by use of an external shell and tube heat exchanger operated in reverse mode, with coolant flowing through the tubes and polymerization mixture flowing through the shell around the tubes. |
| US11078311B2 |
Single-site catalyst polyolefin polymerization process
Disclosed is a method for polymerizing olefins comprising passing a heterogeneous single-site catalyst to a solution or slurry polymerization reactor in the absence of pre-polymerization, wherein the polymerization reactor operates at a temperature of at least 50° C. The heterogeneous single-site catalyst may be suspended and/or dissolved in a solvent selected from the group consisting of oils, aliphatic hydrocarbons and mixtures thereof. Also, the heterogeneous single-site catalyst may be passed to the polymerization reactor at a velocity of greater than 1 m/s or 3 m/s. |
| US11078308B2 |
Processes to produce poly alpha-olefin trimers
The present disclosure generally relates to processes to produce alpha-olefin oligomers and poly alpha-olefins. In an embodiment, a process to produce a poly alpha-olefin (PAO) includes introducing a first alpha-olefin and a first catalyst system comprising a metallocene compound into a continuous stirred tank reactor or a continuous tubular reactor under first reactor conditions to form a first reactor effluent. The alpha-olefin is introduced to the reactor at a flow rate of about 100 g/hr or more. The first reactor effluent includes PAO dimer comprising at least 96 mol % of vinylidene and 4 mol % or less of trisubstituted vinylene and disubstituted vinylene, based on total moles of vinylidene, trisubstituted vinylene, and disubstituted vinylene. The method includes introducing the first reactor effluent, a second alpha-olefin and a second catalyst composition comprising an acid catalyst into a second reactor under second reactor conditions to form a second reactor effluent comprising PAO trimer. |
| US11078307B1 |
Process for polymerizing olefins in the gas-phase
A gas-phase polymerization reactor for the gas-phase polymerization of olefins including a polymerization zone having a recycle line for (a) withdrawing reaction gas from the reactor, (b) leading the reaction gas through a heat-exchanger for cooling, and (c) feeding the reaction gas back to the reactor, wherein the recycle line has the heat-exchanger, a centrifugal compressor having variable guide vanes, and a butterfly valve, and a related process for preparing an olefin polymer in the gas-phase polymerization reactor. |
| US11078305B2 |
Method of reducing the entrainment of polymer in the polymer-lean liquid phase of a separator
The present invention relates to a method of reducing the entrainment of polymer in the polymer-lean liquid phase in a separator, comprising the steps of: (i) Selecting the diameter of the polymer droplets in the polymer solution entering the separator; (ii) Determining the traveling time of the polymer droplets in the separator; and (iii) Adjusting the residence time of the polymer-dense phase in the separator to be at least the traveling time of the polymer droplets, a solution polymerization process using said method for reducing the entrainment of polymer in the polymer-lean liquid phase in the separator and the use of said method for determining the minimum residence time of the polymer solution in the separator required to ensure efficient separation of a polymer solution into a polymer-lean phase and a polymer-rich phase. |
| US11078304B2 |
Process for preparing heterophasic propylene copolymers
Process for producing a heterophasic propylene copolymer using a specific class of metallocene complexes in a multistage polymerization process including a gas phase polymerization step. The invention further relates to the use of catalysts which comprise a specific class of metallocene complexes to produce a heterophasic propylene copolymer in a multistep process including a gas phase polymerization step. |
| US11078298B2 |
Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods
The invention provides anti-UCH-L1 antibodies and anti-GFAP antibodies and their use in vitro detection of UCH-L1 and GFAP, respectively, in a sample from an individual, such as an individual known or suspected of having a brain injury or damage, for example, neurological damage such as mild traumatic brain injury. Also provided are methods, systems and kits for diagnosing brain injury or damage, such as neurological damage, in an individual with the aforementioned antibodies as well as compositions comprising the anti-UCH-L1 antibodies and anti-GFAP antibodies. |
| US11078291B2 |
BCMA antibodies and use of same to treat cancer and immunological disorders
The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA. |
| US11078287B2 |
Binding agonist for treatment of neurological and other disorders
The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof. |
| US11078282B2 |
CD80 variant immunomodulatory proteins and uses thereof
Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided. |
| US11078280B2 |
Oncolytic viral delivery of therapeutic polypeptides
Described herein are pseudotyped oncolytic viruses comprising nucleic acids encoding an engager molecule. In some embodiments, the pseudotyped oncolytic viruses comprises nucleic acids encoding an engager molecule and one or more therapeutic molecules. Pharmaceutical compositions containing the pseudotyped oncolytic virus and methods of treating cancer using the pseudotyped oncolytic viruses are further provided herein. |
| US11078275B2 |
Compound that specifically binds to KIR3DL2 for use in the treatment of peripheral T cell lymphoma
The present invention relates to methods for the treatment, prevention and diagnosis of peripheral T cell lymphoma using compounds that specifically bind KIR3DL2. The invention also relates to use of antibodies that specifically bind KIR3DL2 in diagnostic and theranostic assays in the detection and treatment of peripheral T cell lymphoma. |
| US11078273B2 |
ROR2 antibody compositions and related methods
The disclosure provides antibodies, antibody fragments or antigen-binding fragments, as well as related antibody drug conjugates (ADCs) and chimeric antigen receptors (CARs), that specifically recognize human ROR2, Also provided in the disclosure are methods of using such antibodies in various diagnostic and therapeutic applications. |
| US11078271B2 |
Anti-claudin-2 monoclonal antibody
An object of the present invention is to provide a monoclonal antibody that recognizes an extracellular region of Claudin-2. A monoclonal antibody that specifically binds to an extracellular region of Claudin-2. |
| US11078269B2 |
IL-11Rα antibodies
IL-11Rα antibodies are disclosed. Also disclosed are compositions comprising the IL-11Rα antibodies, and methods using the IL-11Rα antibodies. |
| US11078265B2 |
Anti-IL-23 antibodies
The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies, pharmaceutical compositions and therapeutic and diagnostic methods and compositions for using the same. |
| US11078262B2 |
High viscosity macromolecular compositions for treating ocular conditions
Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions include MAAC solutions or particles present in a therapeutically effective amount, a viscosity-inducing component, and an aqueous carrier component. The compositions have viscosities at about 25° C. of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity at 25° C. is in the range of from about 80,000 cps to about 300,000 cps. |
| US11078258B2 |
Methods of treating and preventing Staphylococcus aureus infections and associated conditions
The present invention relates to methods and compositions for preventing and treating Staphylococcus aureus in a subject. Therapeutic compositions of the present invention comprise leukocidin E and/or D proteins or polypeptides and anti-leukocidin E and/or D antibodies. The invention further relates to methods of identifying inhibitors of LukE/D cytotoxicity and inhibitors of LukE/D-leukocyte binding. |
| US11078257B2 |
Recombinant gram negative bacteria and methods of generating and utilizing same
The present invention provides novel, recombinant Gram-negative bacteria. In particular, the invention provides recombinant Gram-negative bacteria (e.g., E. coli) lacking genes involved in lipopolysaccharide (LPS, endotoxin) biosynthesis (e.g., lacking genes required for core oligosaccharide biosynthesis) and also provides recombinant Gram-negative bacteria lacking genes involved in LPS biosynthesis that contain one or more exogenous KDO transferases and/or one or more exogenous heptosyltransferases (e.g., from one or more types and/or strains of bacteria). The invention further provides methods of generating and utilizing (e.g., as or in an immunogenic composition (e.g., as or in an adjuvant and/or vaccine)) the recombinant Gram-negative bacteria therapeutic, preventative, and/or research applications. |
| US11078251B2 |
T cell receptors (TCR) and uses thereof for the diagnosis and treatment of diabetes
The present invention relates to T-cell receptors (TCR) that recognize pancreatic betacell epitopes and uses thereof for the diagnosis and treatment of diabetes. |
| US11078250B2 |
High-activity long-acting hypoglycemic fusion protein as well as preparation method and medical application thereof
The disclosure provides a high-activity long-acting hypoglycemic fusion protein, which is formed by connecting, via a linker peptide or directly, a high-activity Exendin-4 mutant with an optimally mutated Fc fragment of a human immunoglobulin IgG1. The optimally mutated Fc fragment of the human immunoglobulin IgG1 comprises an optimally mutated human IgG1 hinge region and human IgG1 constant regions CH2 and CH3. |
| US11078243B2 |
Cystine knot scaffold platform
Provided are non-naturally occurring cystine knot peptides (CKPs) that bind to VEGF-A. Additionally, provided are methods of using non-naturally occurring CKPs that bind to VEGF-A, including diagnostic and therapeutic compositions and methods. Non-naturally CKPs that bind low density lipoprotein receptor-related protein 6 (LRP6) are also provided. |
| US11078242B1 |
Peptides for Covid-19 prevention and treatment
Embodiments include therapeutic peptides for preventing or reducing the transmission of a coronavirus such as SARS-CoV2. Also included are methods of using therapeutic peptides for reducing or preventing transmission of a coronavirus such as SARS-CoV2. The therapeutic peptides can prevent a region of the surface glycoprotein “spike” on SARS-CoV2 from interacting with angiotensin converting enzyme-2 (ACE-2) of host cells. |
| US11078236B2 |
Selenium-based therapies
This invention relates to methods of administering compounds containing selenium, selenocysteine, or a selenocysteine peptide to treat, for example, conditions associated with selenium deficiency, or ferroptoptic, parthanototic, and endoplasmic reticulum stress, and/or cancer. The methods of treatment may activate or inhibit (via TFAP2C and Sp1 proteins) the adaptive homeostatic response of the selenome. The compounds may contain a targeting sequence that causes them to be delivered to specific organs and/or tissues. The compounds may be administered, for example, orally, intranasally, intravenously, or by a minimally invasive catheter or BrainPath. |
| US11078234B2 |
Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts
The present disclosure relates to methods of preparing and crystallizing β-turn cyclic peptidomimetic salts of formula I: where R1, R2, R3, R4, R5, R6, R7, R8, R10, X, Y and n are as defined in the specification. The present disclosure provides a more efficient route for preparing a crystalline form of β-turn cyclic peptidomimetic compounds and salts thereof. |
| US11078233B2 |
Tripeptide epoxy ketone protease inhibitors
Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease. |
| US11078230B2 |
2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof
The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7, 8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof. |
| US11078224B2 |
Precursors for the atomic layer deposition of transition metals and methods of use
Metal coordination complexes comprising at least one diazabutadiene based ligand having a structure represented by: where A1, A2, A3, and A4 are atoms in a 6-membered ring and are independently selected from C, N, O, S, and P; and where R1, R2, R3, R4, R5, and R6 are independently selected from the group consisting of H, amino groups, C1-C6 alkyl groups, or C4-10 cycloalkyl groups; and further provided that alkyl groups may optionally contain silicon; and where the metal coordination complex is capable of participating in a Diels-Alder type reaction with a dienophile. Processing methods using the metal coordination complexes are also described. |
| US11078221B2 |
Phosphorodiamidates and other phosphorus derivatives of fingolimod and related S1P receptor modulators
Compounds of general formula (I): (Formula I)) wherein R1, Q, R3, R4, R5, R6, R7 and Ar1 are as defined herein are inhibitors of class I histone deacetylases and are of use in the treatment of lysosomal storage disorders, especially Niemann-Pick type C disease, as well as other lysosomal storage disorders, defective autophagy, accumulation of free cholesterol and mycobacterial diseases. |
| US11078217B2 |
Triplet-triplet annihilation upconversion system, and compositions and methods thereof for drug delivery
The invention provides a novel class of materials that possess triplet-triplet annihilation upconversion, compositions and methods of preparation and use thereof. The invention also relates to use of such materials and nanoparticles, for example, in stimulus-responsive, in situ delivery of biologically active agents. |
| US11078211B2 |
Photoresponsive nucleotide analog capable of photocrosslinking in visible light region
Provided are a compound represented by the following formula I; a novel photoreactive compound that can be used in nucleic acid photoreaction techniques by a photoreactive crosslinking agent comprising the compound; and a photoreactive crosslinking agent in which the photoreactive compound is used. |
| US11078209B2 |
Polycyclic aromatic hydrocarbon derivative, fluorescent material, phosphorescent material, and light-modulating material
Provided is a new polycyclic aromatic hydrocarbon derivative. The polycyclic aromatic hydrocarbon derivative is a derivative of a polycyclic aromatic hydrocarbon having 6 or more aromatic rings and has a substituent represented by the following formula (1). (In the formula (1), R1 and R2 are carbon atoms of the aromatic rings in the polycyclic aromatic hydrocarbon, and R3 to R5 are carbon atoms of an aromatic ring or a heterocyclic ring in a group having the aromatic ring or the heterocyclic ring. n is 0 or 1, and m is the number of substituents.)[Chemical 1] |
| US11078208B1 |
HIV inhibitor compounds
The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I. |
| US11078205B2 |
Selective inhibitors of protein arginine methlytransferase 5 (PRMT5)
The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described. |
| US11078204B2 |
Heterocyclic derivatives as PI3K inhibitors
This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases. |
| US11078203B2 |
Deuterated fezolinetant
Deuterated fezolinetant (R)-(4-fluorophenyl)-(8-methyl-3-(3-(methyl-d3)-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]trizolo[4,3-a]pyrazin-7(8H)-yl)methanone: or a pharmaceutically acceptable salt or solvate thereof, as an NK-3 antagonist. Also, methods of modulating NK-3 receptor activity including administering an effective amount of the compound or pharmaceutically acceptable salt or solvate thereof. Additionally, a process for manufacturing the compound or pharmaceutically acceptable salt or solvate thereof. |
| US11078202B2 |
β-lactamase inhibitor and use thereof
Provided are a β-lactamase inhibitor of formula (I), or an ester, a stereoisomer or a pharmaceutically acceptable salt thereof, and a method of preparing the same. Further provided is a pharmaceutical composition comprising the β-lactamase inhibitor of formula (I), or the ester, the stereoisomer or pharmaceutically acceptable salt thereof. In addition, the present invention relates to a method for treating diseases caused by bacterial infection, which comprises administering the β-lactamase inhibitor of formula (I), or the ester, the stereoisomer or the pharmaceutically acceptable salt thereof to a patient or a subject in need. |
| US11078199B2 |
Quinolone derivatives as fibroblast growth factor receptor inhibitors
Compounds that are Fibroblast Growth Factor Inhibitors (FGFR) and are therefore useful for the treatment of diseases treatable by inhibition of FGFR are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds. |
| US11078195B2 |
Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same
The present invention relates to a novel compounds for inhibiting nicotinamide phosphoribosyltransferase (NamPT), a composition comprising the same, and various uses thereof. |
| US11078189B2 |
Pharmaceutical compounds
Benzimidazole derivatives of formula (I): wherein: R1 is —(CH2)m-R4 or R2 is halo, —(CH2)m—NH2 or —(CH2)n—C(═NH)—NH2; R3 is H or F; R4 is —NH—(CH2)2—(NH)r—R5, —NH—(CHR5R6) or a group of the following formula (A): (A) W is —(CH2)m—, —CH2—O—CH2—, —CH2—S—CH2—, —(CH2)r—S(O)2—CH2— or —(CH2)r—NR5—CH2—; m is an integer of 1 to 3; n is 1 or 2; p is 1 and V is CH; or p is O and V is N; q is 0 or 1; r is 0 or 1; R5 is H, —SO2Me, —SO2Et, —SO2CF3, —COMe, —CONMe2, —CONH2 or —CH2CH2SO2Me; R6 is H or C1-C6 alkyl; and R7 is —SO2Me, —SO2Et, —SO2CF3, —COMe, —CONMe2, —CONH2 or —CH2CH2SO2Me; and the pharmaceutically acceptable salts thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection. |
| US11078188B2 |
Dihydroquinoxaline bromodomain recognition protein inhibitor, preparation method and use thereof
The present invention relates to dihydroquinoxaline bromodomain recognition protein inhibitor, preparation method and use thereof. The inhibitor of the present invention is compound represented by general formula (I), or stereoisomer, pharmaceutically acceptable salt, prodrug, solvate, hydrate and crystal form thereof. The definition of each substituent is as described in the description and claims. The compound represented by general formula (I) of the present invention may inhibit bromodomain recognition protein and may be used for preparing medicament which regulates the apparent state of cells and treats series of diseases and symptoms which are mediated by the bromodomain recognition protein. |
| US11078184B2 |
Dexrabeprazole sodium compound and pharmaceutical composition thereof
A dexrabeprazole sodium compound includes crystal forms B and C. The crystal form B has good stability and flowability. The crystal form C is an anhydrous crystal form and has good stability and low hygroscopicity. The crystal forms are suitable for preparing a dexrabeprazole sodium preparation. |
| US11078181B2 |
Diaryl pyrazole compound and formulation for controlling harmful organisms
A compound represented by the following Formula (I) or a salt thereof, as well as a formulation for controlling harmful organisms, and in particular, an insecticidal formulation, a miticidal formulation, a formulation for controlling ectoparasites or a formulation for controlling or killing endoparasites, which contains at least one compound selected from the compounds of Formula (I) and salts thereof as an active ingredient wherein, each of R1 and R2 independently represents a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, or the like, with the proviso that when R2 represents a hydrogen atom, R1 represents a substituted or unsubstituted C6-10 aryl group or a substituted or unsubstituted 3- to 6-membered heterocyclyl group; R3 represents a C1-6 alkylthio group or the like; each of R4 and R5 independently represents a hydrogen atom, a halogeno group or the like; and Ar represents a substituted or unsubstituted C6-10 aryl group, or a substituted or unsubstituted 5- to 6-membered heteroaryl group. |
| US11078179B2 |
Method for producing cyclic ester
In a method for producing a cyclic ester according to an embodiment of the present invention, a mixture (I) containing an aliphatic polyester, a specific polyalkylene glycol diether, and a sulfonic acid compound as a thermal stabilizer is prepared and heated in predetermined conditions to obtain a mixture (II) in a state of solution. Furthermore, heating of the mixture (II) is continued to distill, together with the polyalkylene glycol diether, a cyclic ester formed by the depolymerization reaction, and thus a distillate (III) is obtained. The cyclic ester is recovered from the distillate (III). At this time, a specific solubilizing agent is added to at least one of the mixture (I) or (II). In this production method, the sulfonic acid compound as the thermal stabilizer is contained in the mixtures (I) and (II) and the distillate (III). |
| US11078177B2 |
Compounds for optically active devices
The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices as well as to ophthalmic devices comprising such compounds. |
| US11078176B2 |
Pubescent plant shallow moving bed solvent extractor and method of use
A shallow bed solvent extractor comprises at least one moving bed having upstream and downstream ends and a feed inlet positioned adjacent to the upstream end, wherein a first batch of wet cannabinoid and terpene containing material is introducible to the at least one moving bed through the feed inlet. An outlet is positioned adjacent to the downstream end, wherein the first batch of wet cannabinoid and terpene containing material is carried on the at least one moving bed and exits the extractor through the outlet. A drive system is operatively connected to the at least one moving bed. The shallow bed solvent extractor further comprises a plurality of sprayers disposed above the upstream and downstream ends of the at least one moving bed and a non-polar solvent. The plurality of sprayers spray the first batch of wet cannabinoid and terpene containing material with the non-polar solvent. |
| US11078174B2 |
Process for making esters of 2,5-furandicarboxylic acid
A process is provided for making esters of FDCA, in which an aqueous feed comprising glucaric acid is first reacted with a high boiling first alcohol in the presence of an acid catalyst and with removing water during the reaction, to form a first product mixture comprising a first ester of FDCA and the high boiling first alcohol, then unreacted high boiling first alcohol is removed from the first product mixture. The first ester of FDCA and the high boiling first alcohol is then transesterified with a lower boiling second alcohol selected from the group consisting of methanol, ethanol, isopropanol and n-propanol, to form a second product mixture comprising a second ester of FDCA with the lower boiling second alcohol, and the second ester of FDCA with the lower boiling second alcohol is recovered. |
| US11078167B2 |
Process for the preparation of Deferasirox
The present invention provides an improved process for the preparation of Deferasirox of Formula-I substantially free from ‘hydrazino impurity’ by the condensation of 2-(2-hydrophenyl)-4H-1,3-benzoxazin-4-one of Formula-IV with 4-hydrazino benzoic acid of Formula-V in a polar solvent. |
| US11078164B1 |
PTEN binding compounds, formulations, and uses thereof
Described herein are compounds and formulations thereof that can bind PTEN. Also described herein are methods of using the compounds and formulations thereof that can bind PTEN. In some embodiments, the method can include administering an amount of a compound or formulation described herein to a subject in need thereof. |
| US11078162B2 |
Processes for preparing AG-10, its intermediates, and salts thereof
Provided herein are improved processes for the preparation of a compound of Formula IX (AG-10). Also provided herein are pharmaceutically acceptable salts of Formula I and Formula Ib as well as crystalline types of Formula IX (AG-10). The processes described herein provide improved yields and efficiency, while the pharmaceutically acceptable salts and crystalline forms provide unexpected pharmacokinetic properties. Other features and aspects of the present disclosure will be apparent to a person of skill in the art upon reading the remainder of the specification. |
| US11078159B2 |
Compounds and methods for inhibiting EMT pathways to treat cancer, organ fibrosis and metabolic disorders
A compound, or a pharmaceutically acceptable salt or isomer thereof, of Formula I: wherein R is hydrogen, alkyl, substituted alkyl, alkenyl, or substituted alkenyl; R1 is hydrogen, alkoxy, or substituted alkoxy; R2 is hydrogen, alkyl, or substituted alkyl; and R3 is hydrogen, alkyl, or substituted alkyl. |
| US11078157B1 |
Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same
Disclosed herein are embodiments of a donor compound that releases H2S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed. |
| US11078140B2 |
Process for producing 1,3-butanediol and for optionally further producing (R)-3-hydroxybutyl (R)-3-hydroxybutyrate
A process is described for producing 1,3-butanediol, wherein an ester of poly-(R)-3-hydroxybutyrate such as formed by transesterification with an alcohol is reduced by hydrogenation in the presence of a skeletal copper-based catalyst to provide 1,3-butanediol. The 1,3-butanediol may be transesterified by reaction with additional poly-(R)-3-hydroxybutyrate ester to produce (R)-3-hydroxybutyl (R)-3-hydroxybutyrate. |
| US11078138B2 |
Sugar hydrogenolysis with molybdenum co-catalyst selective for producing glycols
A hydrogenolysis process is disclosed for directly converting a sugar feed comprised of a high fructose feedstock, a high sucrose feedstock, or a combination of these to a mixed lower polyols product including both propylene glycol and ethylene glycol. The process provides greater propylene glycol selectivity than ethylene glycol selectivity such that the propylene glycol is present to a greater extent than the ethylene glycol in the mixed lower polyols product. The sugar feed and a source of hydrogen are supplied to a reaction vessel and reacted in the presence of a hydrogenolysis catalyst comprising molybdenum (Mo) and ruthenium (Ru). |
| US11078135B2 |
System for producing 1,3-butadiene and method of producing 1,3-butadiene using the system
One aspect of the present disclosure provides a system for producing 1,3-butadiene, which includes: a first supply unit, by which a first feed including a butene raw material, oxygen and steam is supplied; a second supply unit, by which a second feed including a butene raw material and oxygen is supplied; and a reaction unit, which includes a catalyst fixed bed and in which an oxidative dehydrogenation reaction takes place, wherein the first supply unit is connected to a front end of the reaction unit, and the second supply unit is connected to an intermediate end of the reaction unit. |
| US11078132B2 |
Nanowire catalysts and methods for their use and preparation
Nanowires useful as heterogeneous catalysts are provided. The nanowire catalysts are useful in a variety of catalytic reactions, for example, the oxidative coupling of methane to C2 hydrocarbons. Related methods for use and manufacture of the same are also disclosed. |
| US11078130B2 |
Hydrocarbon conversion
The invention relates to hydrocarbon conversion, to equipment and materials useful for hydrocarbon conversion, and to processes for carrying out hydrocarbon conversion, e.g., hydrocarbon pyrolysis processes. The hydrocarbon conversion is carried out in a reactor which includes at least one channeled member that comprises refractory and has an open frontal area≤55%. The refractory can include non-oxide ceramic. |
| US11078124B2 |
Systems and methods for making ceramic powders
Systems and methods for making ceramic powders configured with consistent, tailored characteristics and/or properties are provided herein. In some embodiments a system for making ceramic powders, includes: a reactor body having a reaction chamber and configured with a heat source to provide a hot zone along the reaction chamber; a sweep gas inlet configured to direct a sweep gas into the reaction chamber and a sweep gas outlet configured to direct an exhaust gas from the reaction chamber; a plurality of containers, within the reactor body, configured to retain at least one preform, wherein each container is configured to permit the sweep gas to flow therethrough, wherein the preform is configured to permit the sweep gas to flow there through, such that the precursor mixture is reacted in the hot zone to form a ceramic powder product having uniform properties. |
| US11078119B2 |
Composites of sintered mullite reinforced corundum granules and method for its preparation
The present disclosure relates to a composite of sintered mullite reinforced corundum granules and a method for its preparation. The composite comprises mullite and corundum in an interlocking microstructure. The process for preparing the composite involves the steps of admixing the raw materials followed by sintering to obtain the composite comprising sintered mullite reinforced corundum granules. |
| US11078113B2 |
Process for treatment by a beam of mono- or multicharged ions of a gas to produce antireflective glass materials
A method of treatment using a beam of singly- and multiply-charged gas ions produced by an electron cyclotron resonance (ECR) source of a glass material in which the ion acceleration voltage of between 5 kV and 1000 kV is chosen to create an implanted layer of a thickness equal to a multiple of 100 nm; and the ion dose per surface unit in a range of between 1012 ions/cm2 and 1018 ions/cm2 is chosen so as to create an atomic concentration of ions equal to 10% with a level of uncertainty of (+/−)5%. Advantageously this makes it possible to obtain materials made from glass that are non-reflective in the visible range. |
| US11078110B2 |
Glass wool, and vacuum heat insulation material using same
A glass wool which has physical properties required for a heat insulation material, can be produced industrially, can have reduced hygroscopicity, and has a novel compounding composition. The glass wool having the following glass composition: SiO2: 60.0 to 65.0% by mass inclusive, Al2O3: 0.5 to 2.0% by mass inclusive, Na2O and K2O: 13.0 to 17.0% by mass inclusive, MgO and CaO: 8.0 to 12.0% by mass inclusive, B2O3: 5.0 to 12.0% by mass inclusive, and others: a remainder. |
| US11078106B2 |
Two-step method for strengthening glass
A method of strengthening an alkali aluminoborosilicate glass. A compressive layer extending from a surface of the glass to a depth of layer is formed by exchanging larger metal cations for smaller metal cations present in the glass. In a second step, metal cations in the glass are exchanged for larger metal cations to a second depth in the glass that is less than the depth of layer and increase the compressive stress of the compressive layer. Formation of the compressive layer and replacement of cations with larger cations can be achieved by a two-step ion exchange process. An alkali aluminoborosilicate glass having a compressive layer and a crack indentation threshold of at least 3000 gf is also provided. |
| US11078095B2 |
Water purification agent and water purification method
[Solution] Provided is a water purification agent suitable for use in an automated purification treatment device, when a wastewater purification treatment using a plant-derived water purification agent is performed with the automated purification treatment device. The water purification agent is a granulated product containing a mixture of a plant powder and a polymer coagulant. |
| US11078094B2 |
Process, device and system for treatment of water
The present disclosure provides a particulate matter comprising a combination of crystalline manganese oxide and amorphous manganese oxide, the crystalline form being present and forms passages throughout a cross section of said particulate matter, wherein said crystalline form define a specific surface area that is greater than the outer surface of said particulate matter. Also provided herein is a process for removing chemical contaminants from flowing water making use of the particulate matter and a device and a system comprising the particulate matter. |
| US11078090B2 |
Manifold for domestic water purifier system with specific cartridge replacement
A manifold for domestic water purification systems having flow paths that can be redirected without having to change the physical structure of the manifold or water purification system—a structure to assist with proper installation and stabilization of specific filter cartridges, a memory reader for processing data relating to the state of the filter cartridges, a hinge system to allow for easier installation/removal of new and replacement filter cartridges, and a flow path structure to assist in adding accessories to the water filtration system without requiring a modification to the manifold structure. |
| US11078084B2 |
Aerogel precursor and aerogel prepared using the same
The present disclosure provides an aerogel precursor including an alkoxydisiloxane-based prepolymer and having a functional group derived from a hydrophobic sol-gel forming agent of the following Chemical Formula 1 on a surface thereof, and therefore, capable of enhancing high temperature thermal stability of an aerogel providing hydrophobic pores having uniform pore size distribution when preparing an aerogel, and an aerogel prepared using the same: (in Chemical Formula 1, M, R, R1 to R4 are the same as defined in the specification.) |
| US11078079B2 |
System for creating an oxidation reduction potential (ORP) in water with multi-path manifold for mixing and distribution
A system for creating an oxidation reduction potential (ORP) in water employs a manifold. The manifold includes an enclosure containing a plurality of fluid paths and having one or more ozone intake ports. The ozone intake ports are fluidically coupled to one or more ozone output ports of an ozone supply unit housed in a separate enclosure. A plurality of flow switches are disposed within the enclosure and configured to transmit control signals to one or more controllers of the ozone supply unit in response to sensing a flow of water through the fluid paths in order to cause the ozone supply unit to generate ozone. A plurality of fluid mixers are also disposed within the enclosure. The fluid mixers are fluidically coupled to the ozone intake ports and configured to introduce the ozone generated by the ozone supply unit into the water flowing through the fluid paths. |
| US11078078B2 |
Multi-unit system for creating an oxidation reduction potential (ORP) in water with multi-path manifold for mixing and distribution
A system for creating an oxidation reduction potential (ORP) in water employs a plurality of ozone supply units housed in separate enclosures. The ozone supply units feed into a manifold that contains a plurality of fluid paths and has one or more ozone intake ports. The ozone intake ports are fluidically coupled to one or more ozone output ports of each ozone supply unit. The manifold includes a plurality of flow switches configured to transmit control signals to one or more controllers of each ozone supply unit in response to sensing a flow of water through the fluid paths in order to cause the ozone supply units to generate ozone. The manifold also includes a plurality of fluid mixers that are fluidically coupled to the ozone intake ports and configured to introduce the ozone generated by the ozone supply units into the water flowing through the fluid paths. |
| US11078074B2 |
Integration scheme for microelectromechanical systems (MEMS) devices and complementary metal-oxide-semiconductor (CMOS) devices
Processes for integrating complementary metal-oxide-semiconductor (CMOS) devices with microelectromechanical systems (MEMS) devices are provided. In some embodiments, the MEMS devices are formed on a sacrificial substrate or wafer, the sacrificial substrate or wafer is bonded to a CMOS die or wafer, and the sacrificial substrate or wafer is removed. In other embodiments, the MEMS devices are formed over a sacrificial region of a CMOS die or wafer and the sacrificial region is subsequently removed. Integrated circuit (ICs) resulting from the processes are also provided. |
| US11078073B2 |
Self-processing synthesis of hybrid nanostructures
Provided is a self-processing synthesis of hybrid nanostructures, novel nanostructures and uses thereof in the construction of electronic and optoelectronic devices. |
| US11078071B2 |
Haptic actuators fabricated by roll-to-roll processing
Described is a micro-haptic actuator device that can be fabricated with roll-to-roll MEMS processing techniques. The device includes a first body having a first surface and a second, opposing surface, the body has a chamber defined by at least one interior wall, a piston member disposed in the chamber, physically spaced from the at least one interior wall of the chamber, the piston member having a first surface and a second opposing surface. A membrane layer is disposed over and attached to the first surface of the body, with a portion of the membrane attached to the first surface of the piston member. The device also includes a first electrode supported on a second surface the membrane, and a second body that supports a second electrode, with the second body attached to the second surface of the first body. |
| US11078066B2 |
Post-mix nozzle
Disclosed is a post-mix beverage dispensing nozzle. The dispensing nozzle includes an input fitting, a cap, an insert, and a body. The dispensing nozzle defines a first flow path and a second flow path. The first flow path flows from a first input port offset from a central axis of the dispensing nozzle to a mixing chamber. The second flow path flows from an input port offset from the central axis of the dispensing nozzle to the mixing chamber. At the point of the mixing chamber both the first flow path and second flow path have uniform flow rates in all radial directions around the central axis. |
| US11078054B2 |
Crane
There is provided a crane including a front member capable of derricking, a backstop disposed on a rear surface side of the front member so as to limit a standing operation of the front member, an angle sensor that detects an angle of the front member, an operation detection unit that detects whether or not the backstop is operated, and a controller that controls a derricking operation of the front member. In a case where the controller determines that the angle of the front member is equal to or larger than a predetermined angle, based on a detection signal output from the angle sensor, and determines that the backstop is not operated, based on a detection signal output from the operation detection unit, the controller stops the standing operation of the front member. |
| US11078053B2 |
Support of segmented structural design
A structural support that can be used as a truss girder bridge crane, or the like. The support includes one or more rows 13 of segments 15, that are arranged in side by side relation along the length of the support. Each row 13 has extending there through at least one tensioning element 14 which is anchored at opposite ends of the row and is pretensioned with respect to the row in order to hold the segments of the row together. A support preferably includes one row 13 of segments 15 in a lower chord 11 of the support and another row 13 of segments in an upper chord of the support. Vertical framework is mounted between the chords with ends secured adjacent the segments 15 by the tensioning element. The individual segments and the tensioning elements may be directed to a construction site at the location of use and assembled into rows and the appropriate structural construction. |
| US11078048B2 |
Elevator sheave cleaner
An illustrative example elevator sheave cleaner includes a base configured to be situated on a first side of load bearing members that wrap at least partially around a sheave. A plurality of fingers extend from the base and are configured to be received between adjacent load bearing members. A plurality of cleaning pads are respectively supported by the fingers and spaced from the base. The cleaning pads are configured to contact and clean a surface of the sheave when the cleaning pads are on a second, opposite side of the load bearing members. |
| US11078045B2 |
Electronic safety actuator for lifting a safety wedge of an elevator
An electronic safety actuation device for braking an elevator car includes a safety brake movable between a non-braking position and a braking position, a first electronic safety actuator operably coupled to the safety brake via a first link member, and a second electronic safety actuator operably coupled to the safety brake via a second link member. Operation of the first electronic safety actuator applies a force to the first link member to move the safety brake from the non-braking position to the braking position. Operation of the second electronic safety actuator applies a force to the second link member to move the safety brake from the non-braking position to the braking position. |
| US11078044B2 |
Ring assembly for elevator governor, governor and elevator system
The present invention provides a core ring assembly for an elevator governor, a governor and an elevator system, wherein the core ring assembly comprises: a first portion and a second portion of a core ring which are axially arranged, the first portion and the second portion of the core ring having contact surfaces therebetween; and a pressure generation mechanism for generating a pressure between the first portion and the second portion of the core ring, wherein the first portion of the core ring rotates by receiving an actuation torque from an over-speed actuating mechanism, and the second portion of the core ring rotates with the first portion of the core ring by virtue of friction of the contact surfaces and enables a safety activating module. The core ring assembly provided by the embodiment of the present invention has a peak torque limiting function and a compact structure. |
| US11078043B2 |
Elevator overrun systems
Elevator overrun systems having a first body arranged to be fixedly mounted to a portion of an elevator system or elevator shaft, a second body positioned within the first body and moveable from a deployed state to a retracted state relative to the first body, and a limit switch located at a distal end of the second body, the limit switch configured to interact with a component of an elevator system to prevent movement of an elevator car. |
| US11078042B2 |
Printing apparatus and printing method
A printing apparatus conveys preceding and following sheets to form an overlapping portion where a trailing edge of the preceding sheet and a leading edge of the following sheet overlap each other at a printing position facing an ejection port surface of a printing unit, and prints the preceding and following sheets by ejecting ink from ejection ports based on a relative movement between the printing unit and the preceding and following sheets. The printing unit delays ink ejection timing for printing the overlapping portion of a sheet located closer to the ejection port surface at a position facing the ejection ports from ink ejection timing for printing a non-overlapping portion where the preceding sheet and the following sheet do not overlap each other in one of the preceding sheet and the following sheet. |
| US11078040B2 |
Stand for self contained cartridge and method for manually dispensing an expandable cushioning wrap
An unpowered, manually operable apparatus for dispensing cushioning wrap material drawn concurrently from a roll of separator material and a self-contained cartridge that includes a roll of expandable sheet material. The rolls are supported on a stand for rotation about respective parallel, spaced-apart axes. In addition to the roll, the cartridge includes a tensioning assembly and support panels that abut respective ends of the roll. The tensioning assembly and the support panels cooperate with the stand to control rotational resistance of the roll. The rotational resistance causes the expandable sheet material to expand in length and thickness as it is manually pulled from the stand with the separator material, and support surfaces on the stand hold the cartridge and the separator roll in position. When the cartridge containing the expandable sheet material is depleted, the cartridge is readily removed and replaced. |
| US11078038B2 |
Detector with triangle-shaped inductor coils
A document feeder may include a media transporter to feed a number of sheets of media through a feed path and a detector to detect the presence of a metal object including a number of triangular-shaped inductor coils to detect the metal objects. A method of detecting a metal object coupled to a sheet of media entering a document processing device may include applying an alternating current to a number of triangular-shaped inductor coils to create a magnetic field upstream of a media feed path, detecting a change in a magnetic flux of the magnetic field due to a metal object in the path of said magnetic flux, and producing a warning when the changes in the magnetic flux are detected. |
| US11078037B2 |
Roller conveying unit for conveying a sheet by means of aspiration
A conveying unit includes a rotatable roller having a first through-hole between the inside and the outside of the roller. A cylindrical member inside the roller has an opening and defines an annular chamber between the member and the roller. An insert borne by the roller inserted in the first through-hole thereof and contacting an external surface of the cylindrical member has a second through-hole in communication with the outside of the roller and extending through the first through-hole and the annular chamber. The first through-hole of the opening is configured such that, when the roller rotates, the insert transits at the opening, temporarily placing the outside of the roller in fluid communication with the annular chamber via the second through-hole, so that a sheet outside the roller and at the first through-hole is pulled against the roller by aspirating means and is conveyed. |
| US11078036B2 |
Sheet conveyor and image forming apparatus
A sheet conveyor includes a drive roller, a retard roller forming a nip with the drive roller, a first torque limiter disposed coaxially with the retard roller and communicating with the retard roller, a first gear disposed coaxially with the retard roller, a drive train including a plurality of gears for receiving a driving force from the first gear, a second torque limiter, and an arm member including a contact portion located downstream of the drive roller in the conveyance direction. The arm member is movable between a first arm position to allow transmission of the driving force to the second torque limiter and a second arm position to interrupt transmission of the driving force to the second torque limiter. The arm member is configured to, as the sheet conveyed by the drive roller contacts the contact portion, move from the first arm position to the second arm position. |
| US11078035B2 |
Apparatus and method for dispensing microorganism culture plates
An apparatus for dispensing microorganism culture plates, culture plate loader and culture plate reader comprising the same, as well as method dispensing microorganism culture plates, method of loading such culture plates into a culture plate reader, and method of counting microorganism colonies on such culture plates. |
| US11078034B2 |
Connection for an agricultural vehicle
An agricultural vehicle includes a chassis, a tank carried by the chassis, and at least one meter module coupled to the tank. The at least one meter module has at least one gate. A gate control link is coupled with the at least one gate of the at least one meter module. A control rod is carried by the chassis. A connector couples the control rod to the gate control link at a connection interface such that movement of the control rod controls an open state of the at least one gate of the at least one meter module. The connector has a frangible portion adjacent the connection interface; the control rod and the gate control link uncouples from one another upon a breaking force causing the frangible portion to break. |
| US11078032B2 |
Suction device
A suction device includes an adapter having in the interior thereof a supply passage to which a negative pressure fluid is supplied, a bellows connected to a distal end of the adapter, and a pad member disposed at a distal end of the bellows and to which a workpiece is attracted under suction. In addition, the suction device attracts the workpiece under suction by a negative pressure fluid which is supplied to the pad member through the supply passage and the bellows. An attachment which is capable of being tilted with respect to the axis of the bellows is provided in the interior of the bellows. In the attachment, a main body portion thereof is disposed in facing relation to a suction surface of a skirt, and a shaft portion is inserted into the supply passage at a time that the workpiece is attracted under suction. |
| US11078031B2 |
Conveying apparatus
A conveying apparatus, comprising a drive conveying sub-apparatus. The drive conveying sub-apparatus comprises a first movable supporting film (81), a second movable supporting film (82), a first fixed supporting film (71), and a drive conveying mechanism. The first movable supporting film (81) and the second movable supporting film (82) are respectively located at both sides of the first fixed supporting film (71). The first movable supporting film (81) and the second movable supporting film (82) are both slidably connected with the drive conveying mechanism, so that the drive conveying mechanism drives the first movable supporting film (81) and the second movable supporting film (82) to move up and down and move forward and backward. The first movable supporting film (81), the second movable supporting film (82), and the first fixed supporting film (71) are all provided with grooves having sizes matched with the size of an object to be conveyed. The conveying apparatus can quickly and accurately convey the object to a next station. |
| US11078030B1 |
System and method for an assembly line quick changeout fixture
A conveyor hanger assembly includes an upper fastening end configured to mechanically couple to a conveyor, a lower fastening end configured to couple to an assembly component carrier, and a locking assembly including a locking body extending in longitudinal alignment with and between the upper fastening end and the lower fastening end, and a locking collar positionable between a locked position and an unlocked positioned. |
| US11078029B1 |
Apparatus for profile re-orientation for handling
Conventionally, in industries, different complex profiles (e.g., objects) are extruded and cut to required lengths for handling these profiles. This requires moving profiles from one location to another and placing them together with other similar or identical profiles which is currently a manual process. Present disclosure provides an apparatus for re-orientation of profiles for easy pick and place of these profiles from one location to another location. The apparatus includes actuator arm assemblies that are actuated for movement in upward and downward direction, wherein actuated rollers are trigged to move upward/downward directions accordingly. Profile is placed in initial position on an endless re-orienting belt above the surface of actuator arm assemblies wherein each actuator arm assembly is actuated to move the profile from one sub-region to another sub-region until the profile attains a desired orientation for pick and place of the re-oriented profile to desired location with required angle. |
| US11078028B1 |
System and methods for conveying parts
A method and system for an automatic parts conveying system includes a parts feeder configured to receive parts from a receiving bin, a linear conveyor for conveying parts away from the parts feeder to an installation robot. The installation robot includes a robot arm controlled by a controller and a parts handling device coupled to a distal end of the robot arm. The automatic parts conveying system also includes one or more vibrating elements positioned along at least one of the linear conveyor, the parts feeder, and the receiving bin to impart vibratory motions to the at least one of the linear conveyor, the parts feeder, and the receiving bin for stimulating the parts into motion. The automatic parts conveying system also includes an air assist portion configured to provide pressurized fluid to the parts to facilitate moving parts through the automatic parts conveying system. |
| US11078025B2 |
Lightweight roller
One embodiment provides a lightweight roller, including: a cylindrical tube manufactured using a lightweight material; the cylindrical tube comprising a first end, a second end substantially opposite the first end, and an outer surface; and at least one end cap attached to at least one of the first end and the second end. Other aspects are described and claimed. |
| US11078023B2 |
Guiding device for bulk goods conveyors
A guiding device for a goods conveyor includes a support coupling with a fixed structure of the conveyor at least one sliding profile manufactured as a separate component with respect to the support structure and arranged for coupling with at least one corresponding grooved guide formed on the second side of such support structure and is oriented along the second axis. The grooved guide extends over the entire length of the support structure and includes a central rib arranged to abut against the rear surface of a respective sliding profile. The central rib divides the respective grooved guide into two cavities each having an L-shaped cross-section, so that linear projections are arranged to be inserted into a corresponding cavity of the grooved guide so that the free ends of the linear projections abut against respective abutment walls of the cavities. |
| US11078021B2 |
Steel belt conveying apparatus for transporting and bolting machine and transporting and bolting machine
A steel belt conveying apparatus includes upper and lower horizontal conveying portions, left and right inclined conveying chains, a connecting rod frame, an inclined frame, a drive portion, and a height adjustment cylinder. The left inclined conveying chain is separately connected to the upper and lower horizontal conveying portions. The right inclined conveying chain is separately connected to the upper and lower horizontal conveying portions. A top portion of the connecting rod frame is hingedly connected to an upper horizontal frame of the upper horizontal conveying portion. A bottom portion is hingedly connected to a lower frame of the lower horizontal conveying portion. A top portion of the inclined frame is hingedly connected to an upper horizontal drive shaft of the upper horizontal conveying portion, and a bottom portion is hingedly connected to a lower horizontal drive shaft of the lower horizontal conveying portion. |
| US11078018B2 |
Automatic storage and distribution system, and housing unit and picking unit for products packaged in unit doses
Storage and distribution system for products in unit doses, including plurality of housing units, each including a plurality of locations for products in unit doses. The housing units are organised on a vertical plane to produce at least one portion of a picking wall, in which the locations for products in unit doses face selective picking members. A picking unit includes picking members oriented on the picking wall for picking products packaged in unit doses. A collecting unit, arranged on a second side of the picking unit, includes a rack having a plurality of pegs facing towards the first side of the picking unit. The pegs are reached by the picking members so as to pick therefrom or deposit thereon products packaged in unit doses. The plurality of pegs as a whole can collect a smaller number of unit dose products than those that can be stored in the automatic store. |
| US11078014B2 |
Recyclables dispensing assembly
A recyclables dispensing assembly includes a plurality of panels that are releasably coupled together to form a box for storing recyclables. The box is mounted on a vertical support surface. A door is hingedly coupled to a respective one of the panels such that the door closes a bottom end of the box when the panels are assembled to form the box. Thus, the door retains the recyclables in the box. The door is selectively positioned in an open position to empty the recyclables from the box. A clasp is attached to a respective one of the panels and the clasp is biased to engage the door when the door is closed. The clasp is urgeable to disengage from the door to open the door. |
| US11078012B2 |
Cap for refillable tote
A cap with refill capability and the ability to track various aspects of the tote, cap, and equipment has been developed for use on chemical totes. It provides the ability to refill the tote without removing the cap and remove water from the fluid and air in the hose. |
| US11078010B2 |
Box-in-box container
A container for consumer goods includes a rigid outer box having a hinged lid configured to provide access to an inner volume of the outer box, and a rigid inner box comprising panels separated by fold lines and assembled from an inner box blank. The inner box blank includes a top front panel separated from a top panel by a first transverse fold line, a back panel separated from the top panel by a second transverse fold line, a bottom panel separated from the back panel by a third transverse fold line, a bottom front panel separated from the bottom panel by a fourth transverse fold line, and the top panel and top front panel include side flaps. The inner box blank comprises a plurality of layers including paperboard and bundle wrap. |
| US11078007B2 |
Thermoplastic packaging insulation products and methods of making and using same
Packaging insulation for insertion into a packaging container, which includes an air laid thermoplastic fibrous batt having foldable thermoplastic film material adhered to both sides of the batt. Preferably the thermoplastic material of which the fibers and film are made is the same, and most preferably it is PET. The resulting method and product provides packaging insulation which can be shipped flat and compressed, which expands when unpacked and which can be readily folded to match the interior configuration of a shipping container, such as a cardboard box. |
| US11078004B2 |
Multilayer film for reclosable pet packaging
A multilayer film: an adhesive layer A: an extrudable hot-melt self-adhesive composition; a complexable thin layer B; and a heat-sealable and cleavable layer C of a linear copolyester C1 obtained by polycondensation of a composition of monomers: at least one diol (i), at least one compound (ii) chosen from terephthalic acid or a diester derivative and at least one compound (iii) chosen from an aromatic or aliphatic dicarboxylic acid or a diester or anhydride derivative; the amounts of the monomers (i), (ii) and (iii) used in the polycondensation such that the softening temperature of C1 is below 190° C.A process for producing the multilayer film by co-extrusion blow-molding.A resealable packaging comprising a PET-based receptacle and a seal of said multilayer film, the heat-sealable and cleavable layer (C) of which is heat-sealed on the receptacle. |
| US11078003B2 |
Apparatus, system, and method to conceal the contents of a container
An apparatus to conceal the contents of a container, having first and second containers. The first container has an internal cavity accessible through a first container opening and is configured to hold a first liquid, the first container having a first container coupling element. The second container has an internal cavity, the second container internal cavity configured to hold a second liquid through a second container opening, wherein at least a portion of the second container is receivable through the first container opening into the first container internal cavity in the first container. The second container has a second container coupling element. The first container coupling element of the first container is engageable with the second container coupling element of the second container to selectively couple the second container to the first container. Coupling the second container to the first container conceals the first container opening. |
| US11077995B2 |
Slider lid for beverage container
A lid for a beverage container includes a lid housing with a drink opening, a slider member, and a seal assembly. The seal assembly has a seal arm, a seal and a spring. The slider member slides linearly about the lid housing. A cam pivotally connected to the slider member engages the seal arm. The slider member and cam operate to move the seal arm from an open position to a sealed position. The drink opening is open when the seal arm is in the open position, and the drink opening is closed by the seal when the seal arm is in the closed position. |
| US11077990B2 |
Packaging system for medicated starch-based powder formulations
Medicated starch-based powder formulations are packaged to ensure the medication remains stable for a desired shelf life. The medicated starch-based powder formulation may be packaged in a sealed container so as to maintain medicament functionality for at least one year. The container may be fabricated and/or lined with a low permeability coefficient and sealed with a foil heat induction seal liner. The container may be treated with a media to alter the surface properties of the container to increase the integrity of the container. The medicated starch-based powder formulation may include cornstarch and menthol. |
| US11077985B2 |
Mounting base member, mounting base, and mounting method
Provided is a mounting base member used in a pair for mounting an object to be conveyed thereon, the mounting base member including: a body part configured to support the object to be conveyed; and a top plate part that extends in at least a horizontal direction from an upper part of the body part. The top plate part covers an upper surface of the body part, or the upper surface of the body part contacting the conveyed object is flush with an upper surface of an extending portion of the top plate part. |
| US11077984B2 |
Shipping and display container
A shipping and display container includes a top box installable over a bottom box. The bottom box is configured to receive goods provided in the bottom box in an upright and folded orientation and includes a pair of opposed sidewalls and at least one elongate divider affixed to the bottom box and extending between the opposed sidewalls and configured so as to maintain the goods in the upright and folded orientation. The top box is installable upon the bottom box with the goods received therein in the upright and folded orientation for shipping of the goods and is removable from the bottom box after shipping. The bottom box and the divider cooperate to maintain the goods in the upright and folded orientation for display thereof after removal of the top box. |
| US11077983B2 |
Packaging and packaging blank
The invention provides a packaging comprising opposing and spaced apart front and back panels separated by side panels extending therebetween, wherein a marginal sealing region of each end of the front and back panels is sealed together and wherein at least a portion of an edge of at least one end of the side panels is not connected to the marginal sealed regions of the front and back panels, and, wherein the panels are formed from cartonboard. |
| US11077979B2 |
Small carbonated beverage packaging with enhanced shelf life properties
This disclosure provides new containers, preforms, methods, and designs for small and light-weight carbonated beverage packaging that provide surprisingly improved carbonation retention and greater shelf life, while still achieving light weight. This disclosure is particularly drawn to small PET containers for carbonated beverages, for example less than or about 400 mL, and methods and designs for their fabrication that attain unexpectedly good carbonation retention and shelf life. |
| US11077976B2 |
Piercing member for container access device
A device for transferring fluids includes a piercing member having a distal end and a proximal end and defines a longitudinal fluid channel. An opening is positioned at the distal end of the piercing member with the opening in fluid communication with the longitudinal fluid channel. Further, a sleeve having a proximal end and a distal end includes an extended position where the sleeve surrounds the piercing member and a retracted position where the sleeve is retracted from the distal end of the piercing member. The sleeve defines an opening at the distal end of the sleeve with a gap defined between the retractable sleeve and the piercing member. |
| US11077971B2 |
Developer filling method and developer filling apparatus
A developer filling apparatus includes a bag setting portion where a developer bag in which a developer containing toner and a carrier is sealed is set, an accommodation case setting portion where a developer accommodation case for accommodating the developer is set, and a transfer path constructed to initially fill the developer accommodation case set in the accommodation case setting portion with the developer taken out of the opened developer bag while the developer bag is set in the bag setting portion. |
| US11077968B2 |
Method and facility for filling traveling egg trays
The invention relates to a so-called stabilization method, consisting of completing the filling of traveling egg trays. In each of the successive trays, eggs taken from an available egg reservoir are deposited in empty locations. This reservoir is made up of egg receiving cells that are movable along rows of cells in series. Depending on a filling state of the tray being treated identifying the distribution of the empty locations relative to the full locations, the reservoir is automatically configured in a configuration of egg-bearing cells complementary to said filling state of the tray in progress, so as to next transfer eggs between the reservoir and the tray in progress by correspondence between empty locations and full locations in the tray and the presence or absence of an egg-bearing cell in the reservoir. |
| US11077963B2 |
Dipole drive for space propulsion
The dipole drive is a new propulsion system which uses ambient space plasma as propellant, thereby avoiding the need to carry any of its own. The dipole drive is constructed from two parallel screens, one charged positive, the other negative, creating an electric field between them with no significant field outside. Ambient solar wind protons entering the dipole drive field from the negative screen side are reflected out, with the angle of incidence equaling the angle of reflection, thereby providing lift if the screen is placed at an angle to the plasma wind. Protons entering from the positive side are accelerated out the negative screen, producing thrust. The dipole drive can achieve more than 3 mN/kWe in interplanetary space and better than 10 mN/kWe in Earth, Venus, Mars, or Jupiter orbit and offers potential as a means of achieving ultra-high velocities necessary for interstellar flight. |
| US11077960B2 |
Satellite launch system
A system for launching aerospace payloads includes an unmanned modified lifting body spacecraft (100), with a payload compartment in the forward section of the spacecraft. The spacecraft is propelled by hybrid rockets clustered in the aft section of the spacecraft. Reaction control system (RCS) modules control the flight path and its associated avionics hardware and software. This system also includes a carrier aircraft (200) configured to air-launch the spacecraft. The carrier aircraft includes a flight operations control system, which monitors the spacecraft's payload and monitors and controls launch and flight operations of the spacecraft. A ground-based mission control system monitors and controls the spacecraft's payload and monitors and controls the launch and flight operations of the spacecraft. |
| US11077957B2 |
Selectable barrier filtration system
An air intake system (AIS) has a plenum and an inlet barrier filter associated with the plenum, through which air can selectively enter the plenum. The AIS also has an inlet duct associated with the plenum, through which air can selectively enter the plenum. The AIS also has a bypass door associated with the inlet duct, the bypass door being configured to selectively change an amount of air allowed to pass through the inlet duct. The AIS also has a filter airflow change device configured to change an amount of airflow allowed through the inlet barrier filter. |
| US11077956B2 |
Pressure relief assembly
A thrust reverser of a nacelle may include a translating sleeve and an inner fixed structure a pressure relief assembly. A pressure relief mechanism may include a pressure relief door coupled via a hinge and a latch to the inner fixed structure. Alternatively, a pressure relief door may be coupled to a frame via a hinge and a latch to the inner fixed structure. The pressure relief assembly may limit deflections between the thrust reverser and the pylon in response to a burst duct. The pressure relief door may release from the latch automatically in response to an over pressurization event. |
| US11077950B2 |
Arm restraint latch release assembly
An arm restraint assembly for an ejection seat may comprise a primary arm configured to pivot about a primary arm pivot joint. A latch may be coupled to the primary arm. The latch may comprise a first pair of lugs and may be configured to pivot relative to the primary arm. A primary shear pin may extend between the first pair of lugs. A lanyard may be coupled to the primary shear pin. |
| US11077949B2 |
Dual turbine thermal management system (TMS)
A thermal management system for an aircraft engine. The thermal management system extracts interstage engine bleed air from the engine's compressor and performs three stage cooling of the interstage engine bleed air using two heat exchangers and a vapor cycle system evaporator. The cooled air is then further cooled by expansion through a set of turbines and subsequently used as a heat sink for heat loads on the aircraft. |
| US11077945B2 |
Remote NFC device with aircraft in-flight entertainment (IFE) seatback
Disclosed embodiments are directed at devices, methods, and systems for association of reader devices to IFE monitors in a commercial passenger vehicle. An example method includes determining at a client computing system included in an IFE monitor that at least one reader device is remotely located from the client computing system; using a wired Ethernet connection to a server, the client computing system requesting the server to discover an electronic tag information; and upon the client computing system receiving the electronic tag information from the server over the wired Ethernet connection, the client computing system processing the electronic tag information, wherein another IFE monitor supplies electrical power to the at least one reader device, wherein the client computing system is unaware of a physical location of the at least one reader device, and wherein the server is included in the another IFE monitor. |
| US11077941B2 |
Wing flapping apparatus
A wing flapping apparatus includes a motive power source; a power transmission mechanism; and a wing unit driven by the power transmission mechanism. The power transmission mechanism includes a rotation transmission member configured to rotate upon reception of motive power transmitted from the motive power source; a slider configured to linearly reciprocate in an X-axis direction upon reception of the motive power transmitted from the rotation transmission member and a rotating body configured to reciprocate in a rotation direction upon reception of the motive power transmitted from the slider. The wing unit is configured to swing such that its distal end moves approximately in the X-axis direction as the rotating body reciprocates in the rotation direction. The power transmission mechanism further includes a pair of crank arms each configured to connect the rotation transmission member and the slider. The pair of crank arms each has: one end rotatably connected to the rotation transmission member and the other end rotatably and slidably connected to the slider. |
| US11077940B2 |
Aircraft and method of use
An aircraft includes a fuselage having an interior cockpit to hold one or more seats; a canopy pivotally attached to the fuselage to provide access to the interior cockpit; wings extending away from the fuselage, each having a motor positioned at a first end; a tilting bar extending through the fuselage and engaging with a pivot point associated with each of the wings, the tilting bar allowing for the fuselage to rotate about the pivot bar and thereby stay in an upright position, regardless of the positioning of each of the wings; one or more landing legs positioned aside the fuselage and to support the fuselage during landing; a computing device to control each motor, each motor can be controlled independently; the cockpit is sized to hold one or more people; and the motor of each of the wings provides lifting force. |
| US11077938B1 |
Rotation-stabilized beamed-energy receiver, and associated systems and methods
A rotation-stabilized beamed-energy receiver, and associated systems and methods, including an aircraft carrying a rotating electromagnetic energy receiver that, when rotated, is supported by centripetal force in a selected shape and/or orientation. Accordingly, the receiver can be made from very thin and/or otherwise lightweight/flexible materials, while performing an energy-receiving function. |
| US11077933B2 |
System for driving a flap arrangement between a retracted position and an extended position
A flap system driving a leading-edge flap between retracted and extended positions comprises a leading-edge flap having first and second flap joints, first and second scissor links, a first connecting link, and an actuator. The actuator couples with either the first scissor link or first connecting link. The first scissor link is rotatable supported on a first fixed point by a first support joint. An end of the first scissor link opposite the first support joint couples with the first flap joint. The first connecting link is rotatably supported on a second fixed point by a second support joint. An end of the first connecting link opposite the second support joint rotatably couples with an end of the second scissor link. An opposite end of the second scissor link couples with the second flap joint. The first and second scissor links are rotatably coupled to form a scissor arrangement. |
| US11077929B2 |
Pressure bulkhead system, pressure bulkhead assembly support tool, and method for assembling a pressure bulkhead system
A pressure bulkhead system is presented. The pressure bulkhead system comprises an aft pressure bulkhead having a bulkhead interface surface, skin splice angles positioned adjacent to one another and joined to the aft pressure bulkhead, and a plurality of shims between the flange surface and the bulkhead interface surface of the aft pressure bulkhead. The skin splice angles form a circumferential surface and a flange surface, wherein the circumferential surface has a nominal shape. |
| US11077927B2 |
Hull propulsion mechanism
A hull propulsion mechanism includes a ship body; a wind blade, which is set to the top of the ship body and has a plurality of sails for obtaining a rotating force from wind blade; a shaft, which sustains the wind blade and is a rolling axis as well for conveying the rotating force by the wind blade; a water pump, which is a power unit that circulates water by making use of a turning force from the shaft; and an engine, which obtains hull propulsion from screws that are rotated by a circulated water pressure from the water pump. With this configuration, the hull propulsion mechanism can obtain enough propulsive force without consuming fossil fuels. |
| US11077926B1 |
Tiller assist including hydraulic damper and power steering
A tiller assist hydraulic marine dampener and brake assembly has a fluid flow path with two potential flow restrictors in series. These include a solenoid valve and a hydraulic needle valve. A single cylinder piston serves to close both ends of the flow path. The tiller assist marine dampener and brake assembly in a second embodiment has a central coupling rod with recesses, a coupling link to a tiller arm, a co-axial tube, a nut adjacent each distal end of the co-axial tube securing the co-axial tube to a mounting bracket, a pair of springs co-axial with and surrounding the coupling rod and interior of the co-axial tube, a pair of adjustable end caps closing the gap between the ends of the co-axial tube and the coupling rod while also acting as stops for the springs, and a slide located between the pair of springs, and a set pin. |
| US11077920B2 |
Modular foil system for towed marine array
A marine array having various embodiments of a modular foil system is disclosed. The modular foil system may be configured to generate lift when towed in a marine environment, and thus used to move, position, and/or depress instrument of the array. The modular foil system may include multiple groups of foil sections, each having an angle of attack that is adjustable relative to other groups of foil sections. For example, each group may be supported by a pair of through cables, and an actuator may adjust a tension in one or both of through cables, thereby alerting the angle of attack. The pair of through cables may converge toward one another at connection points adjacent opposing ends of a given group of foil sections of the modular system. The connection points thus establishing a modular framework to couple the given group to other groups of foils of the system. |
| US11077919B1 |
Extendable multihull boat
A lower deck for a watercraft is attached to and supported by an amidships hull, and an actuator slides the lower deck and amidships hull between a stowed position and an extended position on guide rails that are secured to the underside frame of the upper deck that is supported by abeam hulls. When fully extended, the lower deck remains attached to the watercraft while a portion of the lower deck's aft section and the aft end of the amidships hull remains beneath the upper deck. A pair of side beams respectively connect to a port side and a starboard side of the lower deck or the amidships hull. Sliding members, such as rollers and/or guide bars respectively connect to the guide rails, and the side beams respectively engage and slide on the sliding members. |
| US11077918B2 |
Stabilized hull for a keeled monohull sailboat or sail and motor boat
The invention relates to boat building and can be used in the building and modification of sea-going high-speed keeled monohull sailboats or sail and motor boats with a high sail power to weight ratio, where a single, narrow, wave-penetrating displacement hull is used. To provide for the stable controlled movement of a keeled monohull sailboat or sail and motor boat in wave penetration mode, i.e. in a low wave/hydrodynamic resistance displacement mode, both when heeling and when upright (at the same time effectively counteracting heeling and rocking on all courses), and to provide for the damping of the energy of a broken wave and also for the ability of the boat to self-right to an even keel from a “sail-on-water” position, a stabilized hull for a keeled monohull sailboat or sail and motor boat is configured with an overall width of not more than 50% of the length of the hull and has, in the bottom part thereof, a vertically oriented narrow section (4) of low wave/hydrodynamic resistance, which runs longitudinally along the full length of the boat, is symmetrical about the centreline thereof and has a displacement segment (5) comprising a keel (8) with a heavy bulb, wherein the displacement of the segment is equal to the full unladen weight of the boat. The hull further comprises two narrow longitudinally oriented sponsons (6 and 7), arranged symmetrically in relation to the centreline of the boat, which do not bear the weight of the boat and which have a streamlined shape of low wave/hydrodynamic resistance. Said sponsons are situated above the waterline at the maximum width of the hull, forming two tunnel cavities (10) above the waterline to dampen the energy of a wave broken by the bow and the sponsons. |
| US11077914B2 |
Bicycle drive unit
A bicycle drive unit includes a housing, crankshaft and a propulsion assist motor. The housing is configured to be mounted on a frame of a bicycle. The housing includes a first portion and a second portion. The crankshaft is provided to the first portion of the housing. The propulsion assist motor is provided to the second portion of the housing and configured to assist propulsion of the bicycle. The propulsion assist motor includes a rotational axis extending in a direction intersecting a direction in which the crankshaft extends. The second portion has a maximum dimension of smaller than or equal to 75 mm in a direction orthogonal to the rotational axis of the propulsion assist motor. |
| US11077913B2 |
Bicycle frame with integrated shock absorber
The invention relates to a bicycle frame (1) with a remote-controlled shock absorber (2) connected to the frame (1). The shock absorber (2) comprises two dials (3, 4) for adjusting the compression and rebound. The frame (1) is characterised in that it comprises a depression (9; 25) communicated with the outside of the frame (1) and provided with a window (12; 28) that communicates the depression (9; 25) with an inner part (8b; 18b) of the frame (1). An actuator element (7) for adjusting the compression dial (3) extends from the outside of the frame (1) towards the window (12; 28) passing through the inner part (8b; 18b) of the frame (1). The invention improves the integration of the rear suspension of the bicycle while simultaneously allows for easy adjustment of the compression dial (3) and the rebound dial (4). |
| US11077908B1 |
Bicycle shifter user interface
A highly adaptable user interface for gearing based bicycle power transmission devices powered by a linear servo actuator slaved to an electronic control system serving to automatically shift into desirable gearing ratios under user predefined shifting criteria adaptable in real time to rider conditioning, comfort level and road conditions thereby alleviating manual shifting tasks and achieving optimal pedal rate and effort settings for the rider. Ability to switch to manual mode augments rider total control of disclosed device. |
| US11077904B2 |
Knuckle guard
A knuckle guard of the embodiment includes a guard member disposed in front of a grip of a handle of a vehicle, a connecting member connected to the guard member, and a detachment structure provided in an attachment part between the guard member and the connecting member and configured to detach the guard member forward from the connecting member when a load exceeding a set value is applied to the guard member from behind, in which the detachment structure is provided in an inner portion in a vehicle width direction of the guard member. |
| US11077902B1 |
Seating assembly in multiple configurations in a two-wheeled vehicle
A seat assembly for a vehicle having frame, a fender assembly and a longitudinal axis has a first seat pan having a first coupler coupling a first seat to the frame. A cover support is adjacent to the first seat pan. A grab strap is coupled to the first seat pan. A first seat cover is coupled to the first seat pan. A first fastener couples the first seat to the fender assembly. A second seat pan is coupled to the fender assembly with the first fastener. The second seat pan comprising a first opening receiving the grab strap. A second fastener couples the second seat pan to the fender. |
| US11077899B2 |
Conveying apparatus
The conveying apparatus includes support body for supporting object to be conveyed; linear moving member extended at predetermined height position and configured to move in predetermined conveying direction; first guide rail including first slope section inclined in conveying direction from predetermined first height position to second height position different from first height position, and configured to support the support body which moves in first slope section; and transmission mechanism configured to transmit driving force of linear moving member to support body when linear moving member moves in conveying direction. Transmission mechanism vertically extends and contracts in response to change in vertical distance between first guide rail and linear moving member extended at predetermined height position while support body moves on first slope section in conveying direction with being supported by first guide rail. |
| US11077898B2 |
Predictively adjustable hydraulic pressure rails
A robotic device may traverse a path in a direction of locomotion. Sensor data indicative of one or more physical features of the environment in the direction of locomotion may be received. The implementation may further involve determining that traversing the path involves traversing the one or more physical features of the environment. Based on the sensor data indicative of the one or more physical features of the environment in the direction of locomotion, a hydraulic pressure to supply to the one or more hydraulic actuators to traverse the one or more physical features of the environment may be predicted. Before traversing the one or more physical features of the environment, the hydraulic drive system may adjust pressure of supplied hydraulic fluid from the first pressure to the predicted hydraulic pressure. |
| US11077897B2 |
Track system for traction of a vehicle
A track system for traction of a vehicle that is connectable to an axle of the vehicle and includes a track and a track-engaging assembly for driving and guiding the track around the track-engaging assembly. The track-engaging assembly includes a drive wheel for driving the track, idler wheels for contacting a bottom run of the track, and a bogie carrying the idler wheels. The track system includes a transmission for transmitting power from the axle of the vehicle to the drive wheel such that a rotational speed of the drive wheel is different from a rotational speed of the axle of the vehicle. The track system includes a connector disposed between the transmission and the bogie such that the bogie is movable (e.g., pivotable) relative to the transmission. The connector may be disposed below an output shaft of the transmission. |
| US11077895B2 |
Portable trailer stands
Example portable trailer stands for supporting parked trailers are disclosed herein. Some example portable trailer stands disclosed herein comprise two telescopic posts supporting a generally horizontal beam. Some examples include spring-loaded retractable wheels for selectively installing and removing the trailer stand from underneath a trailer left parked on a driveway. After being positioned under the trailer, the posts extend to lift the beam solidly up against the underside of the trailer. To accommodate conditions where the driveway is not parallel to the trailer's underside, some example posts can be lengthened independently and have angular play that allows the beam to tilt. In some examples, the horizontal axle of the trailer stand wheels is perpendicular to the beam so that the trailer stand can be readily installed from either the front or side of the trailer. Some examples have a kingpin-receiving groove in the beam or have some other kingpin-receiving feature. |
| US11077881B2 |
Lower vehicle body structure for vehicle
A lower vehicle body structure for a vehicle includes a floor panel, a pair of side frames, a battery, a left and right pair of side sills, a cross-member, an impact absorption member, and a reinforcement member. The impact absorption member is disposed at a lower surface side of the floor panel and at a position overlapping the cross-member in a front-rear direction of the vehicle body so as to extend in a vehicle width direction between the side frames and the side sills. Also, the impact absorption member is joined to the side frames and the side sills. The reinforcement member is disposed in the cross-member to extend in the vehicle width direction between portions of the cross-member, which correspond to the left and right pair of side frames in the vehicle width direction. |
| US11077878B2 |
Dynamic lane biasing
Techniques for generating trajectories and drivable areas for navigating a vehicle in an environment are discussed herein. The techniques can include receiving a reference trajectory representing an initial trajectory for a vehicle, such as an autonomous vehicle, to traverse the environment in a first drivable area. An object within a distance threshold can be detected in the environment and a second drivable area can be determined. Further, the techniques can include determining a target trajectory based at least in part on the reference trajectory and/or the second drivable area which can provide a region for the object to traverse the environment, and controlling the autonomous vehicle to traverse the environment based at least in part on the target trajectory. |
| US11077877B1 |
Rollover prevention apparatus
The rollover prevention apparatus defines an adaptive steering range limiting device comprising a control unit and a pair of opposing unidirectional brake assemblies mounted to a steering column position detection disc. The rollover prevention apparatus prevents the steering wheel of the vehicle from being turned beyond the threshold of vehicle rollover, but otherwise does not restrict the rotational range of motion of the steering wheel of a vehicle. |
| US11077875B2 |
Rack and a method for producing a rack for a steering gear of a motor vehicle
A rack for a steering gear includes a toothed portion with a toothing extending along a longitudinal axis, and a generally cylinder-segment-shaped back opposite the toothing and having a back radius. A method for producing such a rack includes forming a cylindrical blank with an unmachined radius between a toothed die part having a toothed mold clearance and a back die part having a back mold clearance in a die cavity. The die may have a generally cylinder-segment-shape. In an open position of the die, the blank may be inserted between the toothed mold clearance and the back mold clearance. The toothed die part and the back die part in a forging stroke for closing the cavity may then be moved in a closing direction to a closed position. The back radius of the back mold clearance may be larger than the unmachined radius of the blank. |
| US11077872B2 |
Signal light assembly
A signal light assembly is provided that comprises a multi-position Fresnel lens having a circumference, a first side and a second side. The signal light assembly further comprises a main housing configured to attach to the multi-position Fresnel lens. The multi-position Fresnel lens includes a first plurality of pads and a second plurality of pads on the first side of the multi-position Fresnel lens such that the first plurality of pads and the second plurality of pads are different and alternatively disposed. The first plurality of pads corresponds to a first range operation related to a first focal length. The second plurality of pads corresponds to a second range operation related to a second focal length. The multi-position Fresnel lens is disposed in a first position corresponding to the first range operation or in a second position corresponding to the second range operation based on the use of either the first plurality of pads or the second plurality of pads for assembly between the main housing and the multi-position Fresnel lens. |
| US11077870B2 |
Side sliding door of railway vehicle
A side sliding door of a railway vehicle comprises a door body (100), and a driving device for the opening and closing of a doorway. An outer surface of the door body (100) is flush with an outer surface of the vehicle body when the door body (100) is closed. A movement track of the door body is arranged as an arc-plus-linear reciprocating motion. The outer surface of the door body is flush with the outer surface of the vehicle body when the door body is closed, so that there exists no height difference between the vehicle body and a doorway of the side sliding door. Snow accumulation at doorway under an extreme cold working condition is avoided, and then the risk of a door body being frozen is reduced. |
| US11077869B2 |
Locking assembly
A locking assembly includes an elongated guide tube configured to be coupled to a first component. The guide tube is elongated in a first direction from a first end to an opposite second end. The locking assembly also includes a first pin partially disposed in the guide tube and protruding from the first end of the guide tube. The first pin can be received in a first receiver. The locking assembly also includes a second pin partially disposed in the guide tube and protruding from the second end of the guide tube. This second pin can be received in a second receiver. The locking assembly also includes a handle removably coupled with the second pin. The handle can be grasped and moved to slide the second pin relative to the guide tube and the first pin along the first direction. |
| US11077865B2 |
Method for operating a two-wheeled vehicle, a device, and a two-wheeled vehicle
A method is described for operating a two-wheeled vehicle, in particular a motorcycle, on a roadway, the method including the following steps: ascertaining an instantaneous coefficient of friction between at least one wheel of the two-wheeled vehicle and the roadway; calculating a critical tilt angle of the two-wheeled vehicle as a function of at least the instantaneous coefficient of friction; detecting an instantaneous tilt angle of the two-wheeled vehicle; determining the distance between the instantaneous tilt angle and the critical tilt angle; and outputting an item of information to the driver as a function of the determined distance. |
| US11077862B2 |
Vehicle control system, vehicle control method, and storage medium
A vehicle control system includes a control unit configured to support a driving of a vehicle by selectively operating in one driving support mode among a plurality of driving support modes including a low speed following travel mode in which the vehicle travels while maintaining a constant inter-vehicle distance between a preceding traveling vehicle and the vehicle in a case where the speed is equal to or less than a predetermined speed, and an equipment control unit configured to release a use restriction on a specific function in which the line of sight of a driver is removed from the vehicle surroundings due to its utilization in a case where the control unit operates the low speed following travel mode is executed. |
| US11077860B2 |
Embedded in-vehicle platform for providing immersive user experiences
Systems and methods are disclosed for an embedded in-vehicle platform that provides immersive user experiences. An example method includes obtaining, by a vehicle controller of a vehicle, a preference profile for a user; loading the preference profile by the vehicle controller; determining a shopping experience of the user occurring on a vehicle shopping platform within the vehicle; determining an ambience profile of a merchant identified in the shopping experience; and controlling, by the vehicle controller, an in-vehicle ambience within the vehicle based on the ambience profile and the preference profile. |
| US11077859B2 |
State determination device, state determination program, and computer-readable non-transitory tangible storage medium
A state determination device to determine that a driver driving a vehicle is in a driving difficult state detects an abnormality in a state of the driver, and detects at least one of an abnormality in a driving operation input by the driver or an abnormality in a traveling state of the vehicle. In response to detecting the abnormality in the state of the driver alone, the state determination device does not determine that the driver is in the driving difficult state but determines that the driver is in the driving difficult state in response to detecting the abnormality in the state of the driver and additionally detecting the at least one of the abnormality in the driving operation input by the driver or the abnormality in the traveling state of the vehicle. |
| US11077857B2 |
Device and method for controlling alcohol interlock
A device for controlling alcohol interlock according to an embodiment of the present disclosure includes a sensor for obtaining position information and breath information of a fellow passenger, and a controller that determines whether a blood alcohol concentration of the fellow passenger is measured based on the position information and the breath information of the fellow passenger, and determines whether to re-measure a blood alcohol concentration based on the determination result. Thus, the device may prevent surrogate measurement of the fellow passenger, so that a driver's own blood alcohol concentration may be measured accurately, and drunk driving of a driver may be fundamentally prevented. |
| US11077854B2 |
Apparatus for controlling lane change of vehicle, system having the same and method thereof
An apparatus for controlling a lane change of a vehicle may include: a processor determining whether a condition of interrupting a lane change procedure occurs, during controlling the lane change. In particular, when the condition of interrupting the lane change procedure is satisfied, the processor determines whether to interrupt the lane change procedure or whether to return the vehicle to an original lane to control the vehicle depending on a result of the determinations. The apparatus further includes a storage to store the result determined by the processor. |
| US11077850B2 |
Systems and methods for determining individualized driving behaviors of vehicles
In one embodiment, a computing system of a vehicle may capture, using one or more sensors of the vehicle, sensor data associated with a first vehicle of interest. The computing system may identify one or more features associated with the first vehicle of interest based on the sensor data. The computing system may determine a driving behavior model associated with the first vehicle of interest based on the one or more features of the first vehicle of interest. The computing system may predict a driving behavior of the first vehicle of interest based on at least the determined driving behavior model. The computing system may determine a vehicle operation for the vehicle based on at least the predicted driving behavior of the first vehicle of interest. |
| US11077846B2 |
Controlling an autonomous vehicle based upon a predicted imminent lane change
An autonomous vehicle is described, wherein the autonomous vehicle is configured to estimate a change in direction of a vehicle that is on a roadway and is proximate to the autonomous vehicle. The autonomous vehicle has a mechanical system, one or more sensors that generate one or more sensor signals, and a computing system in communication with the mechanical system and the one or more sensors. The autonomous vehicle is configured to detect an imminent lane change by another vehicle based on at least one of a computed angle between a wheel of the other vehicle and a longitudinal direction of travel of the other vehicle, a degree of misalignment between the wheel of the other vehicle and a body of the other vehicle, and/or an eccentricity of the wheel of the other vehicle. The mechanical system of the autonomous vehicle is controlled by the computing system based upon the detected imminent lane change. |
| US11077844B2 |
System and method for increasing passenger satisfaction in a vehicle having an automated driving system
A system for increasing satisfaction of a passenger in a vehicle having an automated driving system structured to operate the autonomous vehicle may include a first sensor structured to detect a driving environment of the vehicle, the first sensor being operably coupled to the automated driving system; a processor operably coupled to the first sensor and the automated driving system, the processor being structured to calculate a vehicle path plan based on the driving environment of the vehicle and local infrastructure information; and a display operably coupled to the first sensor, the processor, and the automated driving system. The processor may be structured to control the display to display a graphical representation of the driving environment of the vehicle and the vehicle path plan. |
| US11077843B2 |
Sensor module, measurement system, electronic apparatus, and vehicle
A sensor module includes a first sensor device, a second sensor device, and a microcontroller. The first sensor device includes a first synchronization terminal to which an external synchronization signal or a synchronization signal which is a signal based on the external synchronization signal is input, a first interface outputs first measurement data to the microcontroller on the basis of the synchronization signal which is input to the first synchronization terminal, the second sensor device includes a second synchronization terminal to which the synchronization signal is input, and a second interface outputs second measurement data to the microcontroller on the basis of the synchronization signal which is input to the second synchronization terminal. |
| US11077840B2 |
Machine for augmentation, storage, and conservation of vehicle motive energy
A device for addition of motive force to a vehicle, with rotor-plate, rotor-arms, rotor permanent magnets, stator-plate, stator columns, stator electromagnets, and battery, cell, or other energy storage device. The device is retro-fittable on existing wheel assemblies, and installation coverts an internal combustion vehicle to a hybrid with electric propulsion. |
| US11077836B2 |
Method for controlling a hydraulic braking system
In a method for controlling a hydraulic braking system, wherein the braking system includes a hydraulic pump that is driven by an electric motor so as to generate a volume of fluid flow for the hydraulic braking system. the electric motor is controlled in such a manner that fluid pulsation in the hydraulic braking system is counteracted by means of modulating a rotational speed of the electric motor. The modulation is generated by means of the control procedure. Furthermore, a device is designed and configured so as to perform the method. |
| US11077834B2 |
Built-in vehicle jack
A hydraulic system that activates and operates a built-in jack system to enable a driver to change their tires without needing to set up a manual jack system, especially in inclement weather or in a poorly known location. The system is made up of four hydraulic jacks located closely to each tire. A hydraulic pump activated and operated from a control panel will enable one or more of the jacks to actuate due to the hydraulic fluid, lifting the vehicle off of the ground high enough to change a tire. |
| US11077833B2 |
Systems and methods for thermal management of vehicle sensor devices
Methods and systems for thermal management of sensors of a vehicle. The system includes a sensor that is attached to a vehicle, a temperature monitor configured to collect temperature data corresponding to the sensor, a processor, and a sensor cleaning subsystem. The sensor cleaning subsystem includes a cleaning fluid reservoir and a port that is positioned to direct cleaning fluid from the reservoir to the sensor. The processor is configured to: receive temperature data corresponding to the sensor from the temperature monitor, determine whether a current temperature of the sensor is less than a threshold temperature, and in response to determining that the current temperature is less than the first threshold temperature, cause the sensor cleaning subsystem to: heat the cleaning fluid, and initiate a cleaning cycle and direct the heated cleaning fluid to the sensor to heat the sensor. |
| US11077830B2 |
Lidar sensor and control method thereof
A lidar sensor may include: a transmitter configured to transmit laser; a receiver configured to receive reflected laser; a mirror rotating unit configured to rotate a mirror in a designated direction, the mirror serving to reflect the transmitted or received laser; a cleaning device driving unit configured to drive a cleaning device to remove foreign matters adhering to the cover of the lidar sensor; a signal processing unit configured to determine when or where the lidar sensor is covered and calculate a distance to an object; and a control unit configured to control the transmitter not to transmit a laser signal or control a rotational velocity or rotation time of the mirror at a point of time that the lidar sensor is covered by the cleaning device, and control detection or utilization of the received signal when the distance to the object is calculated. |
| US11077826B2 |
Method of processing ambient radio frequency data for activity recognition
A method of operating an activity recognition system includes capturing ambient radio frequency (RF) data by an RF sniffer. The ambient RF data is then received by a processor. The processor reduces noise content of the ambient RF data. Background is then subtracted from the ambient RF data by the processor. The processed ambient RF data is then converted into an image by the processor. The system generates successive images for each one of a plurality of time intervals. An image processing algorithm, stored in a storage medium and executed by the processor, is applied to the plurality of successive images to determine activity recognition. |
| US11077820B2 |
Propellant cage for an inflator, inflator comprising such propellant cage operating method and method of guiding a shock wave of an inflator
The invention relates to a propellant cage (10) for an inflator, especially for a tubular inflator of an airbag module, comprising a substantially tubular base (11) which forms, on the one hand, a gas inlet opening (12a) and, on the other hand, a gas outlet opening (12b) along its longitudinal axis (L), wherein at least one lateral gas flow opening (13) is configured in a circumferential wall (12) of the base (11), wherein the base (11) includes a radially outwardly extending collar (11c) having at least one frontal gas flow opening (14) in the area of the gas flow opening (12c). |
| US11077819B2 |
Decoration member and cover body for airbag apparatus
To provide an emblem having a high engagement force and a cover body for an airbag apparatus provided with the emblem by means of a simple configuration. Emblem body has pin. Pin has shaft section provided with rib and enlargement section formed to be enlarged on the distal end side of shaft section. Pin is inserted through an opening section formed in a cover main body section. Back plate has hole section into which pin is inserted. Back plate has elastic piece section formed at the inner edge of hole section and elastically deformable in the insertion/removal direction of pin with respect to hole section. Elastic piece section abuts against rib of shaft section. |
| US11077818B2 |
Airbag device
An airbag device includes an airbag, an airbag cover which covers the airbag, and a holder which holds the airbag and the airbag cover. The airbag cover includes a door portion which is pushed by the inflating airbag and opened with a hinge portion around a rotation center. A functional component is provided on the door portion and connected to and held by a deformable holding member. The holding member includes a distal side connecting portion connected to the functional component, a proximal side connecting portion connected to a part which can ensure an attachment strength, and a deformation portion which is provided between the distal and proximal side connecting portions and deformed to maintain a connection and holding state of the distal side connecting portion with the functional component and reduce a centrifugal force of the functional component acting on the hinge portion when the airbag is inflated. |
| US11077817B1 |
Airbag assembly inflatable from seat bottom
An assembly includes a seatback and a seat bottom. The seat bottom has a seat bottom frame. The seat bottom frame has a front side spaced from the seatback, a first side extending between the seatback and the front side, and a second side spaced from the first side and extending between the seatback and the front side. An airbag is supported by the front side and inflatable to an inflated position. An external tether extends from the airbag to the seatback. |
| US11077800B2 |
Vehicle mirror having image display function and method for producing the same
A vehicle mirror having an image display function includes an image display device, a circularly polarized light reflection layer, and a front plate formed of glass or plastic in this order. The circularly polarized light reflection layer includes a linearly polarized light reflection plate and a 1/4 wavelength plate from a side of the image display device. The linearly polarized light reflection plate and the 1/4 wavelength plate are directly in contact with each other, or only an alignment layer is included between the linearly polarized light reflection plate and the 1/4 wavelength plate. A method for producing the vehicle mirror includes forming the 1/4 wavelength plate from a composition that is directly applied to the surface of the linearly polarized light reflection plate or that is directly applied to the surface of the alignment layer directly in contact with the linearly polarized light reflection plate. |
| US11077798B2 |
Vehicle exterior monitoring
A vehicle side-view mirror assembly includes an anchor element mountable to a vehicle exterior, and a foldable housing, including a first surface directed in a forward direction when the foldable housing is in an unfolded position, a first capacitive cover and a first electric ground path attached to the first surface, a second surface that is a lateral side surface facing away from the anchor element, a second capacitive cover and a second electric ground path attached to the second surface, a third surface that is a hinged side surface hingedly connected to the anchor element, and a third capacitive cover and a third electric ground path attached to the third surface. Each of the capacitive covers are electrically insulated from one another. |
| US11077795B2 |
Trailer angle detection using end-to-end learning
A trailer angle identification system comprises an imaging device configured to capture an image. An angle sensor is configured to measure a first angle of the trailer relative to a vehicle. A controller is configured to process the image in a neural network and estimate a second angle of the trailer relative to the vehicle based on the image. The controller is further configured to train the neural network based on a difference between the first angle and the second angle. |
| US11077793B2 |
Rearview display device, rearview display method, and program
A video processing unit generates a conversion video having the same angle of view as an angle of view of a mirror image by converting a camera video. The video processing unit causes the generated conversion video to be displayed in a display region such that the conversion video is superimposed on the mirror image. |
| US11077790B2 |
Slide device and light emitting device for slide device
A slide device includes an upper rail to which a slide seat for a vehicle is attached, a slide rail to which the upper rail is slidably attached, a light emitter, and an attachment portion that attaches the light emitter to the upper rail. The attachment portion is attached to the upper rail such that the light emitter is arranged outside the slide rail. According to the slide device, since the attachment portion is attached to the upper rail such that the light emitter is positioned outside the slide rail, the light emitter does not move inside the slide rail to which a large amount of grease is applied, and a decrease in communication performance can be prevented. |
| US11077785B2 |
Device for suspension of a lamp in a vehicle
A device for suspension of a lamp in a vehicle. The device includes a guiding means for guiding the lamp to move relative to the vehicle from a first position to a second position in case of an impact between the lamp and an object. The device further includes at least one energy absorber for counteracting movement of the lamp from the first position to the second position. The guiding means is arranged for guiding the lamp to move inwardly in a movement direction having a movement direction component in parallel with the X-axis while the movement of the lamp being counteracted by one said energy absorber, and to pivot about an axis being transverse relative to the X-axis and the Z-axis, while the pivot motion being counteracted by one said energy absorber, giving the lamp a different orientation in the second position in comparison to the first position. |
| US11077783B2 |
Electromagnetic device for securing and covering cargo
An electromagnetic cover for securing cargo, the cover including a plurality of support members arranged to form a support structure. The electromagnetic cover includes a plurality of electromagnets coupled to the support members, the electromagnets being electrically coupled to a power source. When the power source is activated, the electromagnets generate a magnetic field to magnetically couple the cover to a surface to secure the cargo. Upon deactivating the power source, the electromagnetic cover can be removed to provide access to the cargo. |
| US11077782B2 |
Vehicle seat with extendable and retractable ottoman
A vehicle seat includes a seat base, a backrest connected to the seat base and an leg rest assembly, also referred to as a leg rest assembly. The leg rest assembly includes a deflectable leg support panel pivotably connected to the seat base. The deflectable leg support panel and deflects under a load of legs of the user and returns with a restoring force back to an initial position upon removing the load of the legs of the user. The leg rest assembly may be connected to the vehicle seat by a pivoting structure, that allows the leg rest assembly to be pivoted to a non use position. The leg rest assembly may also be fixedly connected to the vehicle seat a support base front cross structure. This fixed connection then forms an only pivot axis of the leg rest assembly. |
| US11077781B2 |
Pneumatic valve
A fluid bladder valve for a pneumatic vehicle seat adjustment device is disclosed. The valve comprises a first chamber configured to connect to a fluid source, a second chamber configured to connect to the fluid bladder, a third chamber configured to connect to an environment, a fourth chamber connected to the first chamber via a first fluid passage, connected to the second valve chamber via a second fluid passage, and connected to the third valve chamber via a third fluid passage; and an actuator comprising a blocking element disposed in the fourth chamber and an actuator element disposed in the third valve chamber and coupled to the blocking element and configured to move the blocking element between a first position wherein the first passage is opened and the third passage is closed, and a second position wherein the first passage is closed and the third passage is opened. |
| US11077776B2 |
Vehicle seat and seat element equipped with a ventilation and thermal control system
A seat element having a cover and padding configured to serve as support for a user, and having a ventilation and thermal control system that includes a thermoelectric module, a blower, and a conduit delimiting a passage for air connecting the blower and the thermoelectric module. The ventilation and thermal control system is configured for passing a flow of air coming from the cover towards the blower, and the thermoelectric module is configured for cooling and/or heating the airflow. |
| US11077775B2 |
Multi-position anti-rebound bar
A convertible child safety seat may include a body configured to support an occupant, a base portion operably coupled to the body to support the body where the base portion is configured to be disposed on a vehicle seat base of a vehicle seat in either a forward facing configuration or a rearward facing configuration, and a multi-position anti-rebound bar. The anti-rebound bar may be operably coupled to the base portion or the body such that the anti-rebound bar is pivotable between at least a first position to provide a first function in the rearward facing configuration and a second position to provide a second function different than the first function in the forward facing configuration. |
| US11077774B2 |
High torque load power rotary recliner with anti-back drive capability and reduced backlash for car seat
A recliner mechanism includes first, second and third locking plates and a fastener. The first locking plate has a first inner diametrical surface having first teeth formed thereon. The second locking plate has a second inner diametrical surface having second teeth formed thereon. One or both of the first and second locking plates may include an aperture extending therethrough. The third locking plate has an outer diametrical surface having third teeth formed thereon. Some of the third teeth are meshingly engaged with some of the first teeth and some of the second teeth. The fastener may extend through the aperture and is attached to one of a seatback and a seat bottom. |
| US11077772B2 |
Vehicle seat track system
A track system for a vehicle seat includes a lower track with a slide block with lateral slide bar extending along an upper surface of the lower track. The slide block includes a cross web system connecting the first slide bars with a central cross web portion, a forward cross web portion and a rearward cross web portion. A lower track to slide block fastening system includes a central fastener fixing the central cross web portion to the lower track in lateral and longitudinal directions and allowing movement in a direction away from the lower track, a forward fastener fixing the forward cross web portion in the direction away from the lower track and allowing movement in longitudinal directions and a rearward fastener fixing the rearward cross web portion in the direction away from the lower track and allowing movement in the longitudinal directions. |
| US11077762B2 |
Systems, methods, and apparatus for detection of metal objects in a predetermined space
This disclosure provides systems, methods and apparatus for detecting foreign objects. In one aspect an apparatus for detecting a presence of an object is provided. The apparatus includes a resonant circuit having a resonant frequency. The resonant circuit includes a sense circuit including an electrically conductive structure. The apparatus further includes a coupling circuit coupled to the sense circuit. The apparatus further includes a detection circuit coupled to the sense circuit via the coupling circuit. The detection circuit is configured to detect the presence of the object in response to detecting a difference between a measured characteristic that depends on a frequency at which the resonant circuit is resonating and a corresponding characteristic that depends on the resonant frequency of the resonant circuit. The coupling circuit is configured to reduce a variation of the resonant frequency by the detection circuit in the absence of the object. |
| US11077761B2 |
Power supply system for vehicle
To provide a power supply system for a vehicle which can appropriate charge a capacitor on a step-down side, and suppress system failure. The power supply system for a vehicle includes: a high-voltage battery; a first inverter which connects with the high-voltage battery; a drive motor which connects with the first inverter; a high-voltage DCDC converter which steps down the voltage of the high-voltage battery; an accessory, etc. which connects with the high-voltage DCDC converter; a capacitor which connects in parallel with the accessory, etc.; a current sensor, etc. which acquires the charging state of the capacitor; and a VCUECU which controls the high-voltage DCDC converter based on the acquired values of the current sensor, etc. |
| US11077752B2 |
Vehicle accelerator pedal having dual hysteresis generating structure
Disclosed is a vehicle accelerator pedal that may include a cylindrical hinge unit, a lever unit having one side configured to operate in a first direction and another side formed to correspond to an inner circumferential edge of the hinge unit and configured to operate in a second direction opposite the first direction. An outer circumferential edge may be configured to come into close contact with an upper inner circumferential edge of the hinge unit such that a moment of force is applied in a first rotation direction by the hinge unit. An elastic unit having one side may be configured to elastically support one side of the lever unit, the other side formed to correspond to the inner circumferential edge of the hinge unit. An outer circumferential edge may be configured to come into close contact with a lower inner circumferential edge of the hinge unit. |
| US11077751B2 |
Control system of four-wheel drive vehicle and control method of four-wheel drive vehicle
A weight ratio of each driving wheel of the vehicle at the time of automatic driving is calculated, a front and rear distribution ratio of a driving force of the vehicle is calculated from the weight ratio, a rear wheel plan driving force is calculated from the front and rear distribution ratio and an action plan required driving force, and a temperature of a rear wheel motor is estimated. Then, when the estimated attainment temperature of the rear wheel motor is higher than the upper limit value of the temperature, the front and rear distribution ratio is changed within a range in which excessive slip does not occur at the front wheels, the rear wheel plan driving force is recalculated, and the automatic driving of the vehicle is implemented taking the rear wheel plan driving force as a target driving force. |
| US11077750B2 |
Off-road utility vehicle
An off-road utility vehicle includes a frame, an engine, a continuously variable transmission, a transaxle comprising a rear differential, an intermediate drive assembly comprising an intermediate differential, and a front drive assembly comprising a front differential. The intermediate drive assembly and transaxle are coupled via an intermediate driveshaft and the front drive assembly and the intermediate drive assembly are coupled via a front drive shaft. The front drive shaft and the intermediate drive shaft are counter rotating. |
| US11077747B2 |
Vehicle front structure
A front structure of a vehicle includes a front grille opening disposed at the center in the vehicle width direction in a front part of the vehicle; a radiator disposed at the vehicle rear of the front grille opening; an opening disposed on the outer side in the vehicle width direction in the front part of the vehicle; a cooling device disposed at the vehicle rear of the opening; and a guide portion disposed between the opening and the cooling device and guiding traveling air to the cooling device, in which the guide portion has a tubular main body portion extending in the longitudinal direction of the vehicle, and an extension portion extending toward the center in the vehicle width direction from the main body portion and guiding traveling air from the front grille opening to the cooling device. |
| US11077746B2 |
Power split continuously variable transmission with at least four travel ranges
A continuously variable power-split transmission with at least four driving ranges, within which the gear ratio of the power-split transmission can be continuously varied by a variator. A first planetary gearset with a plurality of shafts can be connected via shifting elements with another planetary gearset that also has a plurality of shafts and can be connected with a transmission output shaft. The first planetary gearset comprises four shafts and can be connected, via a first shaft, with a transmission input shaft and a first shaft of the variator. Furthermore, the first planetary gearset is connected, via a second shaft, to a second shaft of the variator, and the first planetary gearset is coupled, via a third shaft, to halves of two shifting elements and, via a fourth shaft, the first planetary gearset is coupled to a shifting element half of a further shifting element. |
| US11077738B2 |
Vehicle component
A vehicle component (1) has a lid (2) for closing a trunk (102). The lid (2) has an air duct opening (3) for letting in and/or letting out an air flow to or from an air duct (4). The air duct opening (3) has a visual screen installation (5) with two visual screen elements (15, 25) formed with passage openings (6). The passage openings (6) are disposed to be mutually offset so that a view into the air duct opening (3) is restricted. |
| US11077737B2 |
Blower unit of air conditioner for vehicle
A blower unit of an air conditioner for a vehicle which allows one actuator to drive two doors in a structure in which at least two doors are provided in an intake duct is disclosed. The blower unit of an air conditioner for a vehicle includes an intake duct including an internal air inlet through which internal air is introduced and an external air inlet through which external air is introduced, a first door configured to adjust an opening amount of a part of the external air inlet and an opening amount of the internal air inlet, and a second door configured to adjust an opening amount of the remaining part of the external air inlet, wherein the first door and the second door are linked and driven together. |
| US11077735B2 |
Heating apparatus of vehicle
A heating apparatus of the invention executes a first heating control for heating a heater core by a heat generation device when a process of heating the heater core is requested while an engine operation is stopped. The heating apparatus executes a second heating control for heating the cooling water which cooled an internal combustion engine, by the heat generation device and supplying the heated cooling water to the heater core when a heater core temperature is not increased to a requested temperature only by the heat generation device. The heating apparatus executes a third heating control for stopping the engine operation, heating the cooling water which cooled the internal combustion engine, by the heat generation device, and supplying the heated cooling water to the heater core when an engine temperature becomes equal to or higher than a predetermined temperature while the second heating control is executed. |
| US11077733B2 |
Dynamic load transfer by switchable air volume suspension
An air suspension system which includes a Dynamic Load Transfer (DLT) function. DLT is a process of transferring vehicle load, or varying normal loads applied to each wheel of the vehicle, using switchable volume or variable volume air spring assemblies. Switchable or variable volume air spring assemblies have the ability to change air spring volumes, which results in changes in air spring rates, which result in changes in normal loads applied to each wheel. Changes in wheel normal loads change wheel traction (slip) and vehicle dynamics (pitch, roll, yaw displacement, rate and acceleration). Each air spring assembly may have multiple volume air chambers that are switched “on” and “off,” a variable volume air chamber, or the air spring assembly may be coupled with other air springs, or air chambers, that are switched or varied. |
| US11077732B2 |
Automotive construction machine, as well as lifting column for a construction machine
Disclosed is an automotive road construction machine, particularly a recycler or a cold stripping machine, comprising an engine frame that is supported by a chassis, a working roller which is stationarily or pivotally mounted on the engine frame and is used for machining a ground surface or road surface. The chassis is provided with wheels or tracked running gears which are connected to the engine frame via lifting column and are vertically adjustable relative to the engine frame. Each individually vertically adjustable lifting column is equipped with a device for measuring the actual vertical state of the lifting column. |
| US11077731B2 |
Vertical hi-rail device
There is described a hi-rail device for mounting on a vehicle, comprising a linkage between an axle assembly for holding wheels and a mounting assembly. The linkage, pivotally connected to an upper pivot connection thereof, is foldable and unfoldable to translate the axle assembly relative to the upper pivot connection. An active suspension between the linkage and the mounting assembly is provided and comprises a suspension body to swivel about the mounting assembly, actuated by a spring proximally urging on the suspension body to provide the swivel. The suspension body comprising the upper connection to the linkage, which can move along with the suspension body to provide active suspension. Also, a locking pin, extending through the linkage, can be locked in a slot using a hydraulic cylinder, distinct from a hydraulic cylinder for deployment, and which comprises a spring for default locking not involving hydraulic power. |
| US11077728B2 |
Tooling and method for galvanizing kingpin coupler
A king pin coupler assembly of a fifth wheel coupling. A coupler plate has a king pin aperture therein. A king pin is positioned to extend axially through the king pin aperture of the coupler plate. The king pin has a first portion with a neck for engaging a fifth wheel of the fifth wheel coupling, the first portion extending to a first side of the coupler plate. The king pin has a second portion on a second side of the coupler plate and welded to the coupler plate. A shielding apparatus is secured to one or both of the king pin and the coupler plate. The shielding apparatus includes a cover sealed to the first side of the coupler plate. The cover extends over the first portion of the king pin to shield the first portion of the king pin during liquid immersion of the king pin coupler assembly. |
| US11077723B2 |
Pneumatic tire
A pneumatic tire 1 comprises an annular bead core 5 embedded in each bead portion 4 of the tire. The bead core 5 is composed of a plurality of wire rings 10 each of which is made of a spirally overlap-wound bead wire 11 and which are arranged in the tire axial direction. The wire rings 11 include a first ring 13 whose bead wire 11 is a twisted cord 13a made of a plurality of filaments 15 twisted together, and a second ring 14 whose bead wire 11 is a monofilament cord 14a made of a single filament. |
| US11077721B2 |
Tire
A mark indicating portion provided on a sidewall portion includes a reference surface provided on a surface of the sidewall portion and marks formed on the reference surface. A surface of each mark is inclined with respect to the reference surface in a direction in which a height thereof increases from one side to the other side in a tyre radial direction. |
| US11077718B2 |
Heavy-duty pneumatic tire
A heavy-duty pneumatic tire comprises a crown rib and a middle rib. The crown rib is provided with crown sipes crossing the crown rib. The middle rib is provided with middle sipes crossing the middle rib and a middle shallow groove having a smaller depth and a larger width than the middle sipes. The middle shallow groove comprises a circumferential middle shallow groove extending in a tire circumferential direction and lateral middle shallow grooves extending from an axially inner side edge (Ema) of the middle rib to the circumferential middle shallow groove so as to terminate at a position thereof. |
| US11077714B2 |
Tire and three-wheeled vehicle with the same
A tire includes a tread portion provided with a tread profile which is curved in an arcuate shape in a tire meridian section so that the tread portion includes a crown region contacting with the ground during straight running, and a pair of shoulder regions contacting with the ground during cornering by leaning the tire at a certain camber angle. The crown region has a land ratio of not less than 98%, and the shoulder regions have a land ratio of from 85% to 93%. A three-wheeled vehicle has a pair of front wheels and a single rear wheel on which the tire is mounted. |
| US11077713B2 |
Tire
A tire comprises a tread reinforcing layer comprising a cord-reinforced part formed by winding a rubberized cord strip with at least one reinforcing cord covered with a topping rubber. The cord-reinforced part includes a mesh part in which first inclined segments and second inclined segments of the rubberized cord strip are inclined to opposite directions with respect to the tire circumferential direction. The first inclined segments intersect the second inclined segments, leaving space parts each having a quadrilateral shape. The mesh part has a tire-equator-side first region, a tread-edge-side second region and a third region therebetween, wherein the space parts within the tire-equator-side first region each have an area A1, the space parts within the tread-edge-side second region each have an area A2, and the space parts within the third region each have an area A3 which is smaller than the area A1 and larger than the area A2. |
| US11077708B2 |
Mobile robot having an improved suspension system
A mobile robot configured to drive on a surface with irregularities, comprising: a chassis having a front end facing a forward direction of travel, a back end, a first side, and a second side. There is a first drive wheel rigidly affixed to the chassis proximate the first side and interconnected to a motor to propel it. There is a second drive wheel rigidly affixed to the chassis proximate the second side and interconnected to a motor to propel it. A first caster assembly is rigidly affixed to the chassis proximate the front end and includes a first caster wheel configured to rotate about a first swivel axis. A second caster assembly is rigidly affixed to the chassis proximate the back end and includes a second caster wheel configured to rotate about a second swivel axis and it includes a compliant member to absorb the irregularities. |
| US11077700B2 |
Multilayer body
A multilayer body includes a transparent first layer. In the transparent first layer, a multiplicity of microlenses arranged in accordance with a microlens grid are impressed in a first region. Furthermore, the multilayer body includes a second layer, which is arranged below the first layer and in a fixed position with respect to the first layer and has a multiplicity of microimages arranged in accordance with a microimage grid and in each case in an at least regional overlap with one of the microlenses of the microlens grid for the purpose of generating a first optically variable information item. The grid pitches of the microimage grid and of the microlens grid in each case in at least one spatial direction are less than 300 μm. |
| US11077690B2 |
Printing apparatus, an amount of displacement calculating method, and a testing chart
A printing apparatus of this invention scans with a tester a testing chart printed by a printing controller to acquire testing image data. A total amount of displacement calculator calculates an amount of displacement of a recording position including a direction of misregister as a total amount of displacement, based on a large amount of displacement determined by a large amount of displacement determiner, a direction of displacement detected by a direction of displacement detector, a shift amount corresponding to an amount of displacement detecting chart determined by an amount of displacement detecting chart determiner, and a peak position of the amount of displacement detecting chart determined by the amount of displacement detecting chart determining unit. Thus, since a total amount of displacement of the misregister can be calculated only by printing the testing chart on web paper WP, an amount of displacement of the misregister in the transport direction can be obtained easily in a short time. |
| US11077686B2 |
Head assembly and inkjet recording apparatus
A head assembly includes a base member, a recording head, a coupling member, and a pressing member. The recording head ejects ink. The coupling member couples the recording head to the base member. The pressing member is in contact with a first surface of the recording head. The coupling member includes an urging member that urges a second surface of the recording head toward the first surface of the recording head. The second surface of the recording head is a surface of the recording head on an opposite side from the first surface. |
| US11077685B2 |
Aligning a carriage within a printing device
A printing device (100, 200) may include a carriage (101, 201) to hold an integrated printhead (103, 203) in the printing device; a manifold latch (105, 205) to connect the integrated printhead and an ink tank connector in a locked position; and a controller (109, 209) to align the carriage within the printing device based on a level of health of the integrated printhead and a latching position of the manifold latch. Furthermore, a non-transitory computer readable medium and a printing method are disclosed. |
| US11077676B2 |
Digital-to-garment inkjet printing machine
Disclosed is a carriage for a direct to garment inkjet printing machine. The machine has a frame having a leading edge, a trailing edge, and a pair of opposed lateral edges. A first row of slots is positioned on the leading edge and a second row of slots is positioned on the trailing edge. The second row of slots is spaced from the first row of slots by a gelling gap. A shelf on the frame supports tanks of white ink and tanks of color ink and a first plurality of tubing connects a tank of white ink positioned on the shelf with a print head in the first row of slots. A second plurality of tubing is for connecting a tank of color ink positioned on the shelf with a print head in the second row of slots. A pair of side heaters attached to opposed lateral edges of the first frame. |
| US11077675B2 |
E-paper imager
An imager includes an ion-emitting unit and a conveying structure to move a passive e-paper display medium in a first orientation along a travel path and to releasably support the display medium in spaced relation to receive airborne ions from the ion-emitting unit for imaging operations. |
| US11077669B2 |
Liquid cartridge capable of reducing leakage of liquid from liquid storage chamber
A liquid cartridge includes: a cartridge casing having a liquid storage chamber; a first wall; a second wall; and an air communication passage. The first wall is positioned upward relative to the liquid storage chamber. The second wall is positioned upward relative to the first wall. The air communication passage has a first communication hole in communication with the liquid storage chamber and a communication opening open to an atmosphere. The air communication passage includes: an air chamber defined by the first wall and the second wall and in communication with the liquid storage chamber through the first communication hole; a second communication hole formed in the second wall; and a labyrinth path. The labyrinth path is positioned upward relative to the air chamber, and has one end in communication with the second communication hole and another end in communication with the communication opening. |
| US11077664B2 |
Systems and methods for controlling the morphology and porosity of printed reactive inks for high precision printing
Systems and methods for optimizing morphology and electrical properties of silver printed on a substrate with a particular implementation in photovoltaic manufacturing techniques. The system comprises a substrate, a printer jet head having a nozzle to dispense a reactive metal ink and a solvent onto the substrate, and wherein the solvent and a temperature of the substrate are controlled during deposition of the reactive metal ink onto the substrate to produce a dense film in the absence of sintering. |
| US11077662B2 |
Liquid discharge head
There is provided a liquid discharge head including: a plurality of pressure chambers aligned in a first direction so as to form first and second pressure chamber groups arranged side by side in a second direction crossing the first direction; a first common channel communicating with pressure chambers constructing the first pressure chamber group; a second common channel communicating with pressure chambers constructing the second pressure chamber group; a first connecting channel connecting one end in the first direction of the first common channel and one end in the first direction of the second common channel; and a second connecting channel connecting the other end in the first direction of the first common channel and the other end in the first direction of the second common channel. Each of the first and second connecting channels overlaps, in a third direction, with any one of the plurality of pressure chambers. |
| US11077661B2 |
Industrial printhead
An industrial printhead comprising an array of piezoactuated flow channel dispensers enclosed in a chamber with a multi-orifice plate allowing fluid exit. |
| US11077651B2 |
Method and process to laminate substrates using an adhesive tape
The present invention discloses a method and process to laminate packaging substrates using an adhesive tape. The tape has a first heat activated adhesive which is activatable at a first temperature and a second heat activated adhesive which is activatable at a second temperature and both of which are alternatively coated on at least one surface of the tape. The method consists of laminating this aforementioned tape to a packaging substrate by following the process of: placing this tape in or on a laminating machine over the packaging substrate, heating the tape at least to the second temperature while making contact with the packaging substrate, cooling the packaging laminate until the second heat activated adhesive is set and cutting a predetermined portion of the packaging laminate before a second adhesive occurs between the tape and the packaging laminate. |
| US11077647B2 |
Thermally conductive silicone rubber composite sheet
Provided is an inexpensive thermally conductive silicone rubber composite sheet. The thermally conductive silicone rubber composite sheet of the invention includes a laminated structure body comprised of an intermediate layer and an outer layer laminated on both surfaces of the intermediate layer, in which(A) the intermediate layer is an electrical insulating synthetic resin film layer having a thermal conductivity of not lower than 0.20 W/m·K and a tensile elastic modulus of not lower than 5 GPa, and(B) the outer layer is a silicone rubber layer of a cured product of a composition containing: (a) an organopolysiloxane; (b) a curing agent; (c) a thermally conductive filler; and (d) a silicon compound-based adhesion imparting agent having at least one kind of group selected from the group consisting of an epoxy group, an alkoxy group, a methyl group, a vinyl group and a Si—H group. |
| US11077645B2 |
Cover member and display device
To provide a cover member excellent in edge safety, and a display device in which said cover member is used. A cover member which covers a display panel of a display device and which has a front surface that does not face the display panel and a rear surface that faces the display panel, said cover member being a laminate in which a first glass plate constituting said front surface and a second glass plate constituting said rear surface are bonded via an intermediate film interposed therebetween, wherein the first glass plate has a first inside chamfer which is a chamfer on the intermediate film side, and the first inside chamfer and the second glass plate or the intermediate film are bonded by a resin. |
| US11077644B2 |
Material systems and methods of manufacturing material systems
A material system may include: an aluminum layer; a glass composite layer adjacent to the first aluminum layer; and a carbon composite layer adjacent to the first glass composite layer, and opposite to the first aluminum layer. A method of manufacturing a material system may include: stacking an aluminum layer, glass composite layer that may include thermoplastic prepreg plies, and carbon composite layer so that the aluminum layer is adjacent to the glass composite layer, and the glass composite layer is adjacent to the carbon composite layer; and consolidating the thermoplastic prepreg plies to soften the aluminum layer. A method of manufacturing a material system may include: stacking an aluminum layer, glass composite layer that comprises thermoplastic resin, and carbon composite layer so that the glass composite layer is between the aluminum and carbon composite layers; and adjusting temperature and pressure to consolidate the stack. |
| US11077643B1 |
Frame material for drones and other unmanned aircraft, and drone frame made from such material
A drone frame includes first and second carbon fiber layers, and a center clear layer positioned between the first and second carbon fiber layers. A cutout is formed through an entire thickness of the first carbon fiber layer so as to expose a portion of the center clear layer. An LED unit is positioned in the cutout. The LED unit has a plurality of LEDs on a bottom thereof such that the LEDs abut the center clear layer. Light is transmitted from the LEDs through the center clear layer so as to illuminate the perimeter of the drone frame. A composite material used in the drone frame and a method of forming the composite material and drone frame are also disclosed. |
| US11077642B2 |
Hot press cushioning material
A hot press cushioning material includes: a first nonwoven fabric forming an inner layer; and second nonwoven fabrics placed on both surfaces of the first nonwoven fabric and forming outer layers. Copolymerized para-aramid fibers having a basis weight of 80 to 400 g/m2 are used as a material of the second nonwoven fabrics. Fibers that are more rigid than the copolymerized para-aramid fibers are used as a material of the first nonwoven fabric. Each of the first nonwoven fabric and the second nonwoven fabrics has a heat resistant temperature of 270° C. or more. |
| US11077641B2 |
Fireproof construction and method for using same
A fireproof structure includes: a first heat-absorbing material that includes an inorganic porous formed body that has absorbed water, or a second heat-absorbing material that includes particles that include magnesium phosphate hydrate and a binder; and a fibrous heat-insulating material that includes inorganic fibers having a shrinkage ratio of 5% or less when allowed to stand at 1,100° C. for 24 hours. |
| US11077631B2 |
Continuous roll-to-roll process design for vertical alignment of particles using electric field
A method of preparing an anisotropic polymer film using an electric field generator. The method of preparing an electric field generator comprising supplying an electric field across an electric field application zone, where the electric field is generated by a first electrode having a first charge and a second electrode having a charge opposite of the first, passing a polymer film that optionally includes dispersed particles through the electric field application zone, where the polymer film contacts the first electrode to induce orientation, and freezing the polymer film to lock the orientation before the polymer film exits the electric field application zone. |
| US11077628B2 |
Method for repairing a composite part
A method for repairing damage to a composite part includes creating an aperture through the composite part and preparing the surfaces surrounding the aperture on both sides of the part; inserting a plurality of resin impregnated fibers through the aperture and spreading the end portions of the plurality of fibers radially against the prepared surfaces on both sides of the part; and maintaining contact of the plurality of fibers with the prepared surfaces while the resin cures. |
| US11077627B2 |
Multi-functional protective assemblies, systems including protective assemblies, and related methods
A protective assembly comprises a first region formulated and configured to provide protection from alpha, beta, and electromagnetic radiation and comprising a composite of particles and polymer; a second region formulated and configured to provide protection from ballistic impact and comprising a composite of fibers and polymer; and a third region formulated and configured to provide protection from thermal radiation and comprising a composite of particles, fiber, and polymer. The protective assembly may be provided on an aerospace structure. The protective assembly may be formed on the aerospace structure body using a co-curing process. |
| US11077624B2 |
System and method for welding thermoplastic components to create composite structure
A system and method for welding thermoplastic components by positioning and moving a heated plate between the components to melt their respective faying surfaces, and as the plate moves, pressing the components together so that the melted faying surfaces bond together as they cool and re-solidify, thereby creating a composite structure. The plate has a heated portion which is positioned between and heated to melt a portion of the first and second faying surfaces. A manipulator mechanism moves the plate along an interface from between the portion to between a series of subsequent portions of the first and second faying surfaces, thereby welding the thermoplastic components along the entire interface to create the composite structure. The heated portion may contact the faying surfaces and melt them through conduction, or may be suspended between them and melt them through radiation and convection. |
| US11077619B2 |
Three-dimensional shaping apparatus and method of manufacturing three-dimensional shaping object
A three-dimensional shaping apparatus includes a plasticizing portion plasticizing a material to generate a shaping material, a nozzle having a discharge port discharging the shaping material toward a table, a movement mechanism changing a relative position between the nozzle and the table, a discharge control mechanism provided in a flow path which connects the plasticizing portion to the nozzle and controlling a discharge amount of the shaping material from the nozzle, and a control portion controlling the plasticizing portion, the movement mechanism, and the discharge control mechanism to shape the three-dimensional shaping object. The control portion controls the discharge control mechanism so that when a relative movement speed between the nozzle and the table is a first speed, the discharge amount of the shaping material is set to a first discharge amount, and when the relative movement speed between the nozzle and the table is a second speed which is slower than the first speed, the discharge amount of the shaping material is set to a second discharge amount which is smaller than the first discharge amount. |
| US11077616B2 |
Apparatus and method for thermal compensation during additive manufacturing
An additive manufacturing apparatus includes an extruder and a gear pump in fluid communication with extruder. The additive manufacturing apparatus also includes a nozzle in fluid communication with the gear pump. The extruder is connected to a guide member such that at least a portion of the extruder is configured to expand and move along the guide member according to a thermal expansion of the extruder. |
| US11077615B2 |
Three-dimensional modeling apparatus and ejection unit
Provided is a three-dimensional modeling apparatus including: a drive motor; a screw that has a groove formation surface with a groove formed therein and that is rotated by the drive motor; a barrel that has a facing surface facing the groove formation surface and having a communication hole at the center thereof and a heater; and a nozzle that ejects a modeling material supplied from the communication hole, in which 0.03≤(Ss/Ls)/(Sn/Ln)≤5.00 (1) where Ss is an average sectional area that is an arithmetic mean between a maximum sectional area and a minimum sectional area of the groove, Ls is a length of the groove, Sn is a sectional area of the nozzle, and Ln is a length of the nozzle. |
| US11077614B2 |
Ledge forming system for producing a conjunct nozzle
A novel ledge forming system used to attach a polymer retention hub to a thin wall nozzle core to provide an efficient way to produce a conjunct nozzle. The inventive apparatus provides a means for assembly of components by a method involving use of a press with a heating element to elevate temperature of a thermoplastic polymer to permit formation of a ledge that overhangs the flange of a nozzle core, mechanically locking components together. Execution of the process is rapid, low cost and eliminates damage to the thin wall of the core that would occur if the polymer retention hub were molded around the nozzle core. |
| US11077611B2 |
Method and device for producing 3D shaped articles with a double recoater
The invention relates to a method and device for producing 3D moulded parts by means of a layer construction technique wherein a recoater is used which can coat in both directions of movement. |
| US11077610B2 |
Method for powder-based additive manufacturing of a part, in particular a lining element for a tire mould
Method for additive manufacturing of at least one component comprises the manufacture, by depositing and selective melting of layers of powder, of at least one intermediate assembly comprising the component produced at an inclined angle and forming an angle of between 20° and 70° with a manufacturing support plate, a support interposed between the support plate and a lower base of the component, and at least one local supporting element resting against the rear frontal face of the component. During the selective-melting phases of the manufacturing step, incipient cracks are formed in regions of connection of the support and of the supporting element to the component. The component is separated from the support and the local supporting element after the manufacturing step by breaking of the connecting regions. |
| US11077602B2 |
Blow-molding machine and method of sterilizing the same
To simply sterilize a blow-molding machine. A mist or gas of hydrogen peroxide or a mixture thereof is introduced through a valve block disposed adjacent to a molding die, thereby sterilizing at least the molding die and an extension rod that extends into the molding die through the valve block. |
| US11077599B2 |
Calibrating device and method for calibrating a film tube
The invention relates to a calibrating device and to a method for calibrating a film tube. An elastically deformable element (704) is secured to the sleeve (703) such that a fluid, in particular a gas, preferably air, can be introduced or discharged via a fluid connection such that a specific pressure P1 and/or a specific volume V1 is set in an area (708) enclosed by the sleeve and the elastically deformable element at a given temperature. Annular bodies (706) and (707) are arranged within the area (708), and a surface section of each annular body (706), (707) supports a respective region of the elastically deformable element (704). The elastically deformable element (704) regions which are supported by the annular bodies are located in the inlet region (711) and the outlet region (712) of the calibrating device for the film tube (713). |
| US11077590B2 |
Mold assembly and method of molding a component
A mold assembly includes a first upper portion, a second upper portion, and a base removably coupled to each other. A method of manufacturing an electrical connector with the mold assembly includes preheating a resin, mixing the resin with a hardener, preheating the mold assembly, injecting the resin hardener mixture into the mold assembly, and curing the resin hardener mixture. |
| US11077589B2 |
Manufacturing method of molded article, molded article, band and timepiece
A manufacturing method of a molded article, including a first step of arranging a primary molded article made of a soft material in a molding die such that an outer peripheral surface of an exposed section of the primary molded article which is exposed to an outside without being embedded in a secondary molded article corresponds to an inner peripheral surface of the molding die, a second step of pressing and deforming an outer peripheral portion of the primary molded article arranged in the molding die by a pressing section so as to bring the outer peripheral surface of the exposed section into close contact with the inner peripheral surface of the molding die, and a third step of molding the secondary molded article by withdrawing the pressing section from inside the molding die while injecting resin to be the secondary molded article into the molding die. |
| US11077587B2 |
Stretchable surfaces with programmable texture
The present disclosure may be embodied as a method for creating a restriction pattern from a mask material having a strain (εmask) an for mapping elastomeric membrane having a strain (εmembrane) into a target 3D shape. The method may include discretizing the target 3D shape into a plurality of radial segments, and a radial strain (εr) is determined for each radial position (r) on each radial segment of the plurality of radial segments. A restriction pattern is determined, wherein the restriction pattern comprises a quantity of mask material for each position r to provide a composite strain (εmask, εsilicone). In some embodiments, the method further includes depositing a first membrane layer into a mold and placing mask material into the first membrane layer according to the determined restriction pattern. The first membrane layer is cured. |
| US11077583B2 |
Precast concrete wall and method
A precast concrete wall structure and method for forming a wall structure are disclosed. A frame is positioned within a casting bed. The frame comprises first and second spaced apart metal tracks which are interconnected by a plurality of metal studs. The casting bed has a plurality of surfaces defining a generally rectangular interior area. A forming member is placed above the frame, the forming member comprising a layer of insulating material defining a plurality of integrally-formed rectangular protrusions extending in a parallel and spaced-apart relationship to one another to define a plurality of rectangular-shaped channels therebetween. Uncured concrete is placed within the casting bed and allowed to cure. |
| US11077571B2 |
Split blade housing with expansion sleeve assembly for power operated rotary knife
A blade housing assembly for a power operated rotary knife including a split blade housing and an expansion sleeve assembly. The split blade housing including an annular blade support section and a mounting section extending from the blade support section. The mounting section includes a split extending through the mounting section and includes a first body portion and a second body portion on opposite sides of the split, the first body portion including a slot extending axially through the first body portion and movable between blade supporting and blade changing positions. The expansion sleeve assembly extends through the slot and includes a split sleeve changeable between first and second circumferences. The expansion sleeve assembly further including a fastener extends through the split sleeve and, when engaged with the split sleeve, maintains the split sleeve in the first circumference and secures the first body portion in the blade supporting position. |
| US11077569B2 |
Shaving systems
Shaving assemblies are disclosed that include a blade unit, an interface element configured to connect the blade unit to a handle, on which the blade unit is pivotably mounted, and a return element disposed between the blade unit and interface element. The return element serves as interface piece, connector and pivot all in one. Shaving systems including such shaving assemblies are also disclosed, as are methods of using such shaving systems. |
| US11077564B1 |
Toroidal suction grippers
Systems, methods, and computer-readable media are disclosed for toroidal suction grippers. In one embodiment, an example device may include a first annular elastic membrane configured to form an orifice having a toroid geometry, and a first vacuum suction device disposed in the first annular elastic membrane. The first annular elastic membrane may be configured to be actuated to grasp an object. |
| US11077559B2 |
Support robot and methods of use thereof
A support robot and control system for timely and efficiently providing at least one of a tool, a part, a component, an electrical supply, and an air supply within an assembly line operation. The support robot and system may include a detection unit for detecting user and a motion planning unit for controlling the motion of the robot based on data received from the detection unit. The support robot may further include an input unit for receiving input from a user. The system may estimate work progress of a user via a work progress estimation unit. The work progress estimation unit may determine work production based on at least an output from the detection unit and information obtained from a work progress database. The system may further include a robot location adjustment unit. The robot location adjustment unit may adjust the location of the robot based on information received from the motion planning unit. Further, the support robot may include a moveable tray, wherein the movable tray is adjusted based on instructions received from the work progress estimation unit. |
| US11077556B2 |
Safety monitoring and control system and methods for a legged mobility exoskeleton device
A method of controlling a mobility device and related device including at least one drive component that drives at least one joint component is described. The control method may include executing a control application with an electronic controller to perform: receiving sensor information from sensors corresponding to a state and/or mode of the mobility device; analyzing the sensor information and determining a control mode of operation based on the sensor information; generating a control signal to output an alert via electronic indicators corresponding to the determined control mode; and controlling at least one drive component of the mobility device to selectively configure and modulate at least one joint component in accordance with the determined control mode of operation. Different alerts may be outputted by the electronic indicators depending on the nature or severity of the alert condition, accompanied by respective device control operations in accordance with the alert condition. |
| US11077552B2 |
Control system, machine learning apparatus, maintenance assistance apparatus, data generating method, and maintenance assisting method
A control system for an actuator includes a non-transitory computer readable medium storing a database in which first information, second information and third information are stored and correlated with each other, and processing circuitry that performs machine learning based on the first information, the second information and the third information stored in the database. The first information is associated with a rotational speed of a reducer in the actuator, the second information is associated with a torque acting on the reducer, the third information indicates a concentration of iron powder in grease in the reducer, and the machine learning builds a concentration estimation model indicating a relationship between the first information, the second information and the third information. |
| US11077546B2 |
Robot
A robot includes a main body provided with a traveling unit, a body display unit disposed on an upper portion of a front side of the main body and elongated in a vertical direction, a head display unit rotatably connected to an upper portion of the body display unit, a rotary motor disposed inside the body display unit, a rotational shaft elongated in a vertical direction and rotated by the rotary motor to rotate the head display unit, and a speaker disposed inside the body display unit, spaced apart from the rotary motor, and overlapping the rotational shaft in a horizontal direction. The robot selectively receives various types of service modules to provide different services. |
| US11077544B2 |
Tool handle and methods of use
A tool handle apparatus and methods of use, for slinging or casting contents therefrom, the tool includes a spade having a spade neck extending from a first spade end, a spade handle having a first handle end a midsection, and a second handle end, said first handle end connected to said spade neck, a spring having a first spring end and a second spring end, said first spring end affixed to said midsection and said second spring end connected to said second handle end, and a looped strap connected to said second handle end and, thus, functions to assist a user in slinging or casting contents therefrom. |
| US11077534B2 |
Method for reconditioning a compactor wheel
A method for reconditioning a compactor wheel of a compaction machine is provided. The method includes mounting a compactor wheel on a positioning system configured to provide one or more of angular adjustment, vertical and horizontal translation, and rotation of the compactor wheel, so as to position the compactor wheel in a desired position. The method also includes providing a welding system configured to perform a submerged arc strip welding or weld cladding operation on the compactor wheel. The submerged arc strip welding or weld cladding operation is performed on at least one surface or edge of the compactor wheel to add weldable material thereto, so as to recondition the at least one surface or edge of the compactor wheel. |
| US11077531B2 |
Fixture block composite structure for workpiece positioning
A fixture block composite structure for workpiece positioning comprises a fixture block group composed of at least a stop fixture block and at least a one-sided movable fixture block. The stop fixture block is fixed to a base by a plurality of mountings, and two opposite lateral sides of the stop fixture block in the extending direction of base are provided with a fixed upright positioning plane respectively. The one-sided movable fixture block has a fixed holder, the holder is fixed to the base by a plurality of mountings. The holder is provided with a movable piece which can be driven to reciprocate towards the positioning plane on the stop fixture block. The movable piece is provided with a clamping surface on one side facing the positioning plane. |
| US11077526B2 |
Laser processing apparatus, methods of laser-processing workpieces and related arrangements
Apparatus and techniques for laser-processing workpieces can be improved, and new functionalities can be provided. Some embodiments discussed relate to processing of workpieces in a manner resulting in enhanced accuracy, throughput, etc. Other embodiments relate to realtime Z-height measurement and, when suitable, compensation for certain Z-height deviations. Still other embodiments relate to modulation of scan patterns, beam characteristics, etc., to facilitate feature formation, avoid undesirable heat accumulation, or otherwise enhance processing throughput. A great number of other embodiments and arrangements are also detailed. |
| US11077519B1 |
Clamping device that develops both axial and circumferential clamping forces in response to a common axial clamping force
Clamping devices and associated methods that are useful to develop both axial and circumferential clamping forces in response to a common axial clamping force. The clamp is able to use a simple mechanism to generate both kinds of clamping forces from a single, axial actuating force. The clamping devices of the present invention are particularly useful for clamping cover and base deck components of a hard disk drive enclosure together to allow the components to be joined and sealed together using welding techniques. |
| US11077518B2 |
Double-head double-sided high-efficiency friction stir welding device and welding method thereof
A double-head double-sided high-efficiency friction stir welding device includes a base (1), a pair of columns (2) arranged on the base (1), an upper beam (3), at least one worktable connected with a horizontal surface of the base (1), vision sensors (7) mounted on the upper head (5) and the lower head (6) and used for identifying the weld, and a CNC controller (8) used for controlling operations of the gantry, the upper head (5), the lower head (6), the worktable and the vision sensors (7). |
| US11077510B2 |
Fine hole electric discharge machine
A fine hole electric discharge machine includes a machining tank, a storage tank, at least one pipeline, a guide base, a liquid current generator, and a controller. The at least one pipeline has at least one opening directed to the upper surface of a workpiece and allows machining liquid to flow through. The liquid current generator selectively forms a first liquid current in which the machining liquid is supplied from the storage tank and jetted from a predetermined opening of the opening, or a second liquid current in which the machining liquid is sucked from an opening the same as or different from the predetermined opening and recovered to the storage tank. The controller controls the liquid current generator to form the first liquid current or the second liquid current. |
| US11077508B2 |
Gear machining apparatus and gear machining method
A gear machining apparatus performs cutting work for a workpiece and generates a gear by performing a feed operation of a gear cutter relative to the workpiece along a direction of an axis of the workpiece while synchronously rotating the gear cutter and the workpiece in a state in which an axis of the gear cutter is inclined with respect to a line parallel to the axis of the workpiece. The gear machining apparatus continuously performs cutting work for a first tooth flank and cutting work for a second tooth flank during a single feed operation, and changes a correction angle between the cutting work for the first tooth flank and the cutting work for the second tooth flank. |
| US11077506B2 |
Transportable machining unit, structure and stack arrangement
A transportable machining unit for machining a workpiece with a tool including a box-shaped support structure placed on a support and having a workpiece support plate used to support the workpiece and a drive unit for mechanically driving the tool, arranged at least partially in the support structure and fastened thereto ready for operation so that the drive unit remains at least partially in the support structure during machining of the workpiece by the tool driven by the drive unit. The support structure has supporting arms which define a footprint of the support structure and which can be positioned selectively in a transport or working position. The footprint of the support structure is larger in the working position in at least one horizontal direction than in the transport position. |
| US11077505B2 |
Table saw
A table saw has a base assembly, a table assembly supported by the base assembly, the table assembly, and a saw assembly supported by at least one of the table assembly and the base assembly. The saw assembly has a saw blade extending through the table assembly. The base assembly has at least one foot having a substantially horizontal surface, a substantially vertical surface, and a curved surface disposed between the substantially horizontal surface and the substantially vertical surface. The substantially vertical surface is substantially coplanar with a surface of the table assembly so that the table saw can be disposed on the substantially vertical surface and the surface of the table assembly. |
| US11077503B2 |
Machining method and machining device
Provided are a machining method and a machining device that can reduce the displacement from a target round shape due to elastic deformation after machining, and can shorten the time required to machine a target round shape in the work. A machining method machines a round hole in a work, and includes: a hole-shape acquisition step of acquiring a shape of a hole of the work; an inverted-shape acquisition step of inverting the shape of the hole acquired at the hole-shape acquisition step relative to a target round shape to acquire an inverted shape; and an inverted-shape machining step of machining the hole in accordance with the inverted shape acquired at the inverted-shape acquisition step. |
| US11077501B2 |
Method of machining a rotationally symmetric surface of a workpiece and turning apparatus
In accordance with various illustrative embodiments of the present disclosure, a rotationally symmetric surface of a workpiece is machined by a turning apparatus, wherein the workpiece is rotationally driven around a rotational axis, a cutting tool with a cutting edge positioned at the edge of a rake face is arranged relative to the workpiece, the cutting tool is brought into contact with the workpiece, and the cutting tool is advanced relative to the workpiece along a feed direction parallel to the rotational axis, the normal to the rake face being tilted relative to the feed direction, a first axis and a second axis, the first axis and the second axis are perpendicular to the feed direction and perpendicular to each other. |
| US11077497B2 |
Deoxidation of metal powders
Systems, methods, and compositions disclosed herein provide for low-oxygen metal powders. These metal powders, such as very-fine powders and spherical powders of titanium and titanium alloys, can be effectively deoxidized through use of vapor deoxidation without requiring the powder to undergo re-sizing or re-shaping subsequent to the deoxidation. Systems, methods, and compositions in accordance with the present disclosure can produce low-cost, low-oxygen, metal powders, such as very-fine powders and spherical powders of, for example, titanium and titanium alloys. Moreover, systems, methods, and compositions in accordance with the present disclosure can provide for reducing the number of processes or cost of processes required to produce these low-oxygen metal powders. |
| US11077494B2 |
Method and casting core for forming a landing for welding a baffle inserted in an airfoil
A method and casting core for forming a landing for welding a baffle inserted into an airfoil are disclosed, wherein the baffle landing of the blade or vane is formed in investment casting by the casting core rather than by wax, reducing tolerances and variability in the location of the baffle inserted into the cooling cavity of airfoil when the baffle is welded to the baffle landing. |
| US11077491B2 |
Continuous casting apparatus and corresponding method
Continuous casting apparatus comprising a plurality of compression units (11), each of which is defined by a lower roll (12) and an upper roll (13) configured to exert a compression action on a cast metal product (P). Each lower roll (12) defines with the respective upper roll (13) a passage gap (14) for the metal product (P). The passage gaps (14) of the compression units (11) are disposed aligned along a casting axis (Z) with an at least partly curved development. A straightening roll (15) is disposed on the extrados side of said casting axis (Z) and between at least two of the lower rolls (12). |
| US11077487B2 |
Metal form containing dispersed aerogel particles impregnated with polymers and a method of producing the same
A composite structure including a metal form. The composite structure further includes an aerogel matrix formed of an aerogel, with the aerogel matrix being nanoporous and including a plurality of aerogel pores. A polymer occupies at least a portion of the aerogel pores of the aerogel matrix. The polymer is a thermoplastic. The thermoplastic is nanoporous and includes a plurality of thermoplastic pores. The thermoplastic pores are less than 10 nanometers in size. The polymer is impregnated within the aerogel pores of the aerogel matrix. The aerogel comprises at least 20% by weight of the composite structure. The aerogel pores are less than 10 nanometers in size. The composite structure further contains filler material. The filler material may be graphene. The composite structure further contains reinforcing agents. |
| US11077485B2 |
Rotary forge device testing device, testing tool, testing method, bearing unit manufacturing device, bearing unit manufacturing method, and vehicle manufacturing method
The inspection device of the swing forging apparatus includes an inspection tool and a laser irradiation surface. When inspecting the swing forging apparatus, the inspection tool is supported to the head to which the processing roll is not supported, with a substantially same condition as the processing roll, and the inspection tool has a function of emitting a laser beam onto a central axis of the inspection tool. When inspecting the swing forging apparatus, the laser irradiation surface is arranged so that a relative position of the laser irradiation surface to the head in an axial direction of the head can be changed and the laser beam can be irradiated to the laser irradiation surface. |
| US11077483B2 |
Appartus and method for steering metal pipe during grooving process
An apparatus for steering a metal pipe during a roll grooving process including a clamp to be secured to a static structure of a grooving press spaced apart from a rotating cylinder of the grooving press, a pair of spaced parallel rods slidably disposed through spaced openings of the clamp, a handle affixed to first ends of the pair of spaced parallel rods distal from the rotating cylinder, and a guiding tool affixed to second ends of the pair of spaced parallel rods proximate to the rotating cylinder carrying spaced rollers adapted to contact an outer surface of a metal pipe during a roll grooving process to apply a force against the metal pipe. A method for applying a force against a metal pipe during a roll grooving process. |
| US11077481B2 |
Method for manufacturing ring-rolled product
A method for manufacturing a ring-rolled product forms the ring-rolled product from a ring material by using a mandrel roll and a main roll. The mandrel roll and the main roll are configured so as to contact inner and outer circumferential surfaces of the ring material, respectively, and are configured so as to press the ring material in a radial direction thereof in a state in which the ring material is rotated in a circumferential direction thereof. The method includes a step of rolling the ring material that includes an operation of induction-heating the main roll by at least one induction heating element and rolling the ring material between the mandrel roll and the main roll, which is induction-heated. |
| US11077479B2 |
Pressing device and method for controlling pressing device
A pressing device is capable of selectively pressing either a coiled material or a sheet material. The pressing device includes a pair of bars and a first retracting mechanism. Each bar includes a holding section capable of holding the sheet material, a first end section separably linked to the holding section on an upstream side of the holding section along a conveyance direction of a material, and a second end section separably linked to the holding section on a downstream side of the holding section along the conveyance direction. The first retracting mechanism is configured to move the first end sections to an upper first retracted position during the pressing of the coiled material. |
| US11077476B2 |
Methods and compositions for In Situ groundwater remediation
Groundwater, slurry, or soil treatment or remediation compositions and methods of both production and use are described that include: at least one colloidal remediation chemical, at least one polysaccharide stabilizer, and at least one enzyme. |
| US11077475B2 |
Neuro-chemical sensor with inhibition of fouling on nano-electrode
A biosensor includes an array of metal nanorods formed on a substrate. An electropolymerized conductor is formed over tops of a portion of the nanorods to form a reservoir between the electropolymerized conductor and the substrate. The electropolymerized conductor includes pores that open and close responsively to electrical signals applied to the nanorods. A dispensing material is loaded in the reservoir to be dispersed in accordance with open pores. |
| US11077473B2 |
Cleaning device for blood vessel sealing apparatus
A cleaner device is adapted to clean a blood vessel sealer device. The cleaner device includes a series of brushes that can move relative to blood vessel sealer device to scrub and clean the blood vessel sealer device when coupled to the cleaner device. The brushes can be made of any material that is adapted to clean the blood vessel sealer device. The cleaner device can also be motorized to facilitate cleaning of the blood vessel sealer device. |
| US11077472B2 |
Cleaning apparatus and method of object detection sensor
A cleaning apparatus of an object detection sensor may include: an environment information acquisition unit configured to acquire surrounding environment information of a vehicle; and a cleaning unit configured to create a cleaning solution mixture based on the surrounding environment information acquired by the environment information acquisition unit, and clean a cover installed on the object detection sensor to protect the object detection sensor from foreign matter by spraying the created cleaning solution mixture onto the cover, in order to prevent a reduction in sensing performance of the object detection sensor due to contamination by the foreign matter. The object detection sensor may sense a target object by transmitting a scan signal to the target object and receiving a sensing signal reflected from the target object, and the scan signal and the sensing signal may be transmitted and received through the cover. |
| US11077470B2 |
Sorting system with multiple sorting devices
A system for sorting waste objects is disclosed. According to an aspect of the present disclosure, the system includes at least one sorting unit, in which the sorting unit is connected to at least one sensor system that identifies the waste objects. The sensor system is arranged to detect one or more waste object characteristics and is also arranged to provide a control system with a signal when a waste object of a desired type is detected. The system also includes at least one sorting conveyor that conveys the waste objects to the sorting unit in which the sorting unit is provided with two or more sorting devices that sort the waste objects. The sorting devices of the present disclosure are arranged to receive at least one signal from the control system in response to a waste object of a desired type being detected by the sensor system. |
| US11077468B2 |
Device and method for classifying seeds
The present invention relates to a device and method for classifying seeds, for example coffee seeds. The device is characterised by: a seed-feeding mechanism; a seed-containing mechanism connected to the seed-feeding mechanism; an electronic seed-viewing system operationally disposed in the seed-containing mechanism; a seed-ejecting mechanism connected to the outlet of the seed-containing mechanism, the electronic seed-viewing system having a central processing unit that implements methods for classifying seeds. The method is characterised by the steps of: a) obtaining a digital image of the seed; b) storing the RGB components of the image obtained in step a); c) generating a histogram for each colorimetric and luminosity component of the histogram of step b); d) determining the thresholding point according to Otsu's method; e) obtaining a binary image; f) removing areas; g) obtaining the edges; h) obtaining the vectors corresponding to the seeds; i) identifying black seeds; j) identifying seeds with fermentation- and immaturity-related defects; k) identifying seeds with mechanical damage; and l) actuating a seed-ejecting mechanism, activating actuators for black seeds, actuators for seeds with fermentation- and immaturity-related defects and actuators for seeds with mechanical damage. |
| US11077466B2 |
End effector with slides for transferring trays
An end effector for transferring a tray is described. The end effector includes an end effector base attached to a vertical drive column of a tray engine. The end effector further includes a slide having multiple arms that are attached to the end effector base to support the tray, when present. The arms of the slide enable the tray to slide along a length of the end effector base. The arms face each other and extend along the length of the end effector base. |
| US11077463B2 |
Method for the layered manufacturing of a structural component and device
The invention relates to a method for the layered manufacturing of a structural component from powder, comprising the following steps: establishing at least one parameter (t) of a depression (1) in a produced layer (2) of the structural component; smoothing out the depression (1) if the at least one parameter (t) exceeds a predetermined value; and filling the smoothed-out depression (1) with powder (13). |
| US11077461B2 |
Apparatus and methods for use in applying a fluid to a surface
A fluid application system includes a pair of identical, spaced apart, fluid applicators that each include a fluid permeable pad saturated with fluid. In one implementation, each applicator includes a pair of conduits coupled to a base plate, wherein each conduit includes a slot configured to receive an end of the pad. In another embodiment, each applicator defines a reservoir between adjacent plates and channels fluid from the reservoir though openings in the plate to the pad. In another implementation, each of the applicators includes a base plate, a conduit coupled to the base plate, and a housing slidably coupled to the base plate. The housing includes a plurality of pads and is moveable to selectively prevent fluid flow between the conduit and the pads in a first position or to couple the pads in fluid communication with the conduit in the second position. |
| US11077460B2 |
Traveling water delivery device
A device to moving a water shooter is described. The device may contain features that allow the device to travel submerged in a reservoir with a water shooter attached. The device may travel along a fixed track, rotational boom, or be free swimming in order to move the water shooter within the reservoir so that unique water effects may be achieved. |
| US11077453B2 |
High-pressure rotor nozzle
The invention relates to a high-pressure rotor nozzle comprising a main body having a channel for supplying a highly pressurised fluid, a nozzle holder which can be rotationally driven for this purpose via a hydraulically generated torque, and which has at least one nozzle connected to the channel in a manner open for fluid and acting in accordance with an axial recoil, wherein a leakage chamber forming a hydraulic axial bearing during operation is provided between the main body and the nozzle holder that can be axially adjusted in relation to same in a recoil-dependent manner, with said leakage chamber being connected to a first gap seal between the main body and the nozzle holder guiding a leakage fluid, wherein the high-pressure rotor nozzle is designed in such a way that the leakage chamber transitions into at least one throttle gap circumferentially surrounding the nozzle holder in an axial sub-region and varying in the axial extension thereof according to the movement path of the nozzle holder, wherein the throttle gap remains the same height over the axial length thereof. |
| US11077452B2 |
Process, apparatus, and system for recovering materials from batteries
The present application provides a process to recover materials from rechargeable lithium-ion batteries, thus recycling them. The process involves processing the batteries into a size-reduced feed stream; and then, via a series of separation, isolation, and/or leaching steps, allows for recovery of a copper product, cobalt, nickel, and/or manganese product, and a lithium product; and, optional recovery of a ferrous product, aluminum product, graphite product, etc. An apparatus and system for carrying out size reduction of batteries under immersion conditions is also provided. |
| US11077451B2 |
Interface and control set
The invention relates to an interface and control unit (27) for a cooking appliance, comprising: a control circuit (19) comprising a connection point (20) for connecting to a power circuit (18) of the cooking appliance (A) or to an element for connection to said power circuit (18), the control circuit being arranged so as to emit a control signal for at least one functional element of the cooking appliance; a communication circuit (25) arranged so as to communicate according to a known communication protocol, for example a protocol for two-way communication by radio waves, the communication circuit (25) also being able to exchange information with the control circuit (19); and a support to which are attached, or in which are arranged, the control circuit (19) and the communication circuit (25), the support comprising elements for fixing to a frame of the cooking appliance (A). |
| US11077450B2 |
Service platform and jaw crushing assembly including same
A jaw crusher assembly comprising a jaw crushing apparatus and a service platform. The jaw crushing apparatus having first and second opposing jaws, each opposing jaw having a crushing face. The crushing faces opposing each other in an oblique relationship when the opposing jaws are in an at least partially opened state. The service platform provides at least two service configurations within the opposing jaws and being operable between a first service configuration and a second service configuration by rotation of the service platform. |
| US11077442B2 |
Apparatus and method for extracting pathogens from biological samples
The disclosed embodiments related to an apparatus and methods for biological sample processing enabling isolation and concentration of microbial or pathogenic constituents from the sample. Sample may be obtained directly from a specimen container, such as a vacutainer, and processed directly without risk of user exposure. The disclosed methods and apparatus provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques. |
| US11077439B2 |
Micro-fluidic system using micro-apertures for high throughput detection of cells
A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target entities bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target entities from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target entities bound to magnetic beads on the surface of the plate. In a further feature, the microfluidic detection system is configured to pass target molecules through the plate to be bound to a functionalized surface of the lower chamber. |
| US11077436B1 |
Mailable inspector collector
The Mailable Inspector Collector is a (1) single-use device for (2) user-friendly collection, inspection, and (3) rendering of test results to confirm or deny the presence of a pathogen using (4) Nanotechnology with an (5) portable isothermal assay methodology, which may (6) reveal results, via color change and/or fluorescence (e.g. FAM channel excitation 470 nm to 520 nm.), the presence of at least one specific pathogen. The Mailable Inspector Collector invention can be (7) administered, distributed and disposed of by leveraging a delivery infrastructure, such as that offered by the United States Postal Service (USPS), to address the following known issues: (8) Mass distribution to the public; (9) Recycling of used elements; (10) Easy non-intrusive manner whereby a Test Subject may contribute a sample; (11) Easy manner to discern test results within minutes without complex laboratory equipment; (12) Facilitate relevant data collection as well as contact tracing. |
| US11077434B2 |
Method of preparing metallocene catalyst for polyolefin preparation
A method of preparing a high-purity metallocene catalyst capable of providing various selectivities and high activities for polyolefin copolymers, wherein a metallocene compound is formed by reacting a ligand compound with a zirconium compound, and then lithium chloride as a reaction by-product included in the metallocene compound is prepared in a form of a complex compound and effectively removed in a subsequent step of extracting the catalyst, thereby effectively preparing the high-purity metallocene catalyst, is provided. |
| US11077430B2 |
Oxidative dehydrogenation catalyst
Oxidative dehydrogenation catalysts comprising MoVNbTeO having improved consistency of composition and a 25% conversion of ethylene at less than 420° C. and a selectivity to ethylene above 95% are prepared by treating the catalyst precursor with H2O2 in an amount equivalent to 0.30-2.8 mL H2O2 of a 30% solution per gram of catalyst precursor prior to calcining. |
| US11077429B2 |
Catalyst composite for conversion of methane gas and method for converting methane gas using the same
The present disclosure relates to a catalyst composite for conversion of methane gas, which includes Co3O4 nanoplates and ZrO2 nanoparticles adsorbed to the surface of the Co3O4 nanoplates, and is used for converting methane gas into alcohols, and a method for conversion of methane gas using the same. When using the catalyst composite, it is possible to convert methane gas into alcohols with high efficiency under a mild condition of room temperature and ambient pressure. |
| US11077428B2 |
Hydrogenolysis catalysts with high acid tolerance
A catalyst includes a mixed metal oxide; an alumina; silica, and calcium, where the mixed metal oxide includes Cu and at least one of Mn, Zn, Ni, or Co. Such catalysts exhibit enhanced tolerance sulfur-containing compounds and free fatty acids. |
| US11077424B2 |
Oxygen scavenger composition
The present invention provides an oxygen scavenger composition comprising a granule having: an α layer containing a water retention agent, a swelling agent, a metal salt and water; a β layer containing iron; and a γ layer containing a porous support, wherein the granule forms a layer structure in order of the α layer, the β layer and the γ layer from an inside to an outside of the granule. |
| US11077423B2 |
Highly stable [MaMbF6-n(O/H2O)n(Ligand)2(solvent)x]n metal organic frameworks
Embodiments of the present disclosure describe metal-organic framework compositions comprising a pillar characterized by the formula (MbF5(O/H2O)), where Mb is selected from periodic groups IIIA, IIIB, IVB, VB, VIB, and VIII; and a square grid characterized by the formula (Ma(ligand)x), where Ma is selected from periodic groups IB, IIA, IIB, IIIA, IVA, IVB, VIB, VIIB, and VIII, ligand is a polyfunctional organic ligand, and x is 1 or more; wherein the pillaring of the square grid with the pillars forms the metal-organic framework. |
| US11077420B2 |
Methods for the treatment of a flue gas stream in a flue gas train including a baghouse
A sorbent composition for enhanced baghouse function is described. The composition may include a sorbent such as powder activated carbon as well as an additive that is a heat moderator or a permeability agent. The heat moderator may act as a heat sink or barrier. Heat moderators may include in non-limiting examples phyllosilicates, cyclosilicates, or nesosilicates that may include, montmorillonite, bentonite, halloysite, aluminum silicates, muscovite, illite, kaolin, andalusite, kyanite, sillimanite, metakaolin, mullite, polymers, such as chitosan, and/or clays, either natural or synthetic (e.g., montmorillonite), or polyethylenimine. Permeability may be affected by mixing sorbents of lower D50 with sorbents of higher D50 in various ratios, or addition of a permeability agent such as a phyllosilicate, perlite, silica, diatomaceous earth. Further, a permeability agent such as a fluoropolymer may be coated onto or admixed with the sorbent. Diatomaceous earth, perlites, or silicates may also increase permeability. The compositions are particularly useful in flue gas treatment systems with baghouse separation units in that they have reduced combustibility and increased permeability properties. |
| US11077415B2 |
Methods for forming mixed droplets
The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet. |
| US11077409B2 |
Automated solution dispenser
The methods and systems of the invention include the use of automated solution dispensers in laboratory environment. The automated solution dispensers can be controlled locally or remotely within a network. The usage of the instruments can be followed and procurement of supplies can be automated. |
| US11077407B2 |
Porous hollow-fiber membrane and production process therefor
The porous hollow-fiber membrane of the present invention comprises a fluororesin polymer, and has columnar structures oriented in the longitudinal direction thereof. In the porous hollow-fiber membrane, molecular chains of the fluororesin polymer have been oriented in the longitudinal direction of the porous hollow-fiber membrane and have an average value ν of Raman orientation parameter of 1.5-4.0. |
| US11077401B2 |
Separated gas stream point of use abatement device
Embodiments of point-of-use (POU) abatement device and methods of abating a plurality of gas streams from a corresponding plurality of processing chambers are provided herein. In some embodiments, a compact POU abatement device includes a plurality of inlets respectively coupled to a plurality of process chambers in which each of the process chambers gas streams is isolated from the other gas streams. In some embodiments, the compact POU abatement device can include a plurality of oxidation devices and a corresponding plurality of wet scrubber columns each directly coupled to ones of the plurality of inlets to receive a gas stream from a corresponding process chamber. |
| US11077397B2 |
Honeycomb filter
A honeycomb filter includes a plugged honeycomb structure body which has cell rows arranged along one direction, in a cross section of the honeycomb structure body and including a first cell row constituted of at least one of an inflow cell and an outflow cell, and a through-cell, and a second cell row including no through-cells. A width P1 (mm) of the first cell row, a width P2 (mm) of the second cell row and a curvature radius R (μm) of a curved shape of corner portions of a polygonal shape of each cell satisfy a relation of Equation (1) below: Equation (1): 0.4 (R/1000)/((P1+P2)/2) 100 20. |
| US11077391B2 |
Automatic flushing type pre-filtering device
Disclosed is an automatic flushing type pre-filtering device, that includes: a valve head set, a filter cartridge set, a movable rod piece, and a drain valve set. The filter cartridge set includes: a cylinder body; a filter cartridge, disposed in the cylinder body, the filter cartridge includes a filter net rack and a filter net disposed on the filter net rack. A first chamber is formed between the filter cartridge and the cylinder body, and a second chamber is formed inside the filter cartridge. The movable rod piece is provided with a hollow portion inside, and the movable rod piece is disposed in the second chamber. A water separation piece is disposed between the movable rod piece and the filter net rack. A plurality of through holes are disposed on the movable rod piece corresponding to a position of the second chamber. |
| US11077390B2 |
Separating drilling cuttings and gas using a liquid seal
A gas separator, gas separation system, and method for separating gas from drilling cuttings by actively maintaining a liquid seal of liquid in a lower portion of a separation vessel by controlling an introduced amount of the liquid admitted to the separation vessel as a removed amount of the liquid is removed from the separation vessel and by promoting agitation of the drilling cuttings in the liquid in an agitation chamber within the lower portion of the separation vessel to aid removal of the drilling cuttings along with the removed amount of the liquid. |
| US11077387B2 |
Test track
A test track assembly comprising a test track, the test track comprises a support structure and at least one track portion, adapted for testing a spatial structure; the test track assembly comprises at least two different interchangeable track sections, each of the at least two interchangeable track sections comprises an action track portion, each of the action track portions comprise a different geometrical track path, the action track portions adapted to provide geometric challenges to a user who tests a spatial structure on the test track, the support structure comprises a void adapted to accommodate one of the at least two interchangeable track sections in position such that the action track portion is arranged adjacently in continuation to the at least one track portion, the track portions comprises a starting point and a ending point, which are positioned opposed each end of the test track, wherein the test track assembly comprises a toy construction system, the toy construction system comprises several toy construction elements, the toy building elements comprise one or more coupling organs adapted to be interconnected to form a spatial structure, said spatial structure adapted to be tested on said test track. |
| US11077386B1 |
Interlocking toys
The invention comprises a plurality of rectangular prism and/or cubic blocks. The sidewalls of the blocks comprise various combinations of grooves and/or pegs. Each groove extends along the respective sidewall within which it is disposed, from a corner wherein the top wall and the respective sidewall intersect to a corner wherein the bottom wall and the respective sidewall intersect. Each peg is configured to be slidably received into a groove disposed on another block within the plurality of blocks. |
| US11077385B2 |
Magnetic plate toy
A magnetic plate toy includes a plurality of magnets and a polygonal plate member that includes a plurality of accommodation onions. A first magnet is movable along a side wall of the plate member and is rotatable about a first rotation axis oriented along the length of the first magnet and about a second rotation axis oriented along a thickness direction of the plate member. The plurality of accommodation portions are disposed along one or more side walls of the plate member, and a first accommodation portion include a first end portion. A width of the first end portion is equal to or greater than the width of the first magnet, the width of the first end portion is less than the length of the first magnet, and a width of an accommodation space in the first accommodation portion is greater than the width of the first end portion. |
| US11077384B2 |
Electric ride-on vehicle with safety control
An electric toy vehicle includes a vehicle body having a front compartment and a rear compartment. A set of surface engaging members is rotatably connected to the vehicle body. A motor is operatively connected to the surface engaging members. A moveable divider is positioned between the front compartment and the rear compartment. The divider is moveable between a first position and a second position. A switch includes a first state and a second state. When the divider is in the first position the switch is in the first state and when the divider is in the second position the switch is in the second state. When the switch is in the first state, the motor is prevented from operating the surface engaging members. |
| US11077383B2 |
Nozzle for inflating a balloon
A nozzle includes an expansion portion and a coupling portion having an inner end, an outer end, and an air hole extending from the inner end through the outer end. A connecting portion is connected between the expansion portion and the inner end and includes an opening intercommunicating with the air hole. The nozzle is coupled with a neck of a balloon. The expansion portion spreads the neck. The opening is received in the neck. The air hole intercommunicates with an inflation space defined in the balloon when a gas with a sufficient pressure is filled into the air hole. The air hole does not intercommunicate with the inflation space when no gas with the sufficient pressure is filled into the air hole. |
| US11077381B1 |
Wheel for a toy car
A wheel for a toy car can include a cylindrical portion and a conical portion, where a first width of the cylindrical portion is narrower than a second width of the conical portion. |
| US11077377B2 |
Method for game loading and related products
A method for game running and related products are provided. The method is applicable to an electronic device and the method includes the following. A game to be run is determined. A first file of the game is downloaded by requesting a network. The first file is decompressed to obtain a second file decompressed. At least one game engine is called to load the second file to run the game. |
| US11077376B2 |
Managing game metrics and authorizations
Various metrics as may be deployed in an active, passive, or hybrid validation architecture are disclosed. A computing device configured to monitor network game activity may identify an inconsistency between user game data and a particular game metric governing a particular aspect of the network gaming environment. Upon identification of an inconsistency between game data and a game metric, which may indicative of illicit game play, a validation process (e.g., active, passive, and/or hybrid) may be implemented to further confirm the existence of illicit game. Alternatively, an action to maintain integrity of the gaming community may be executed without further confirmation whereby a purportedly illicit game device may be ejected from the network. |
| US11077372B2 |
Method for controlling a display element by a games console
A control process of a display element, the process comprising the steps: measuring a position of a control lever, projecting in a base plane the position of the lever to determine a first set of coordinates, determining a homothetic figure on a mechanical stop of the lever, determining a circumscribed square on the homothetic figure, projecting onto the circumscribed square at least one coordinate of the first set of coordinates, calculating a second set of coordinates in a Cartesian reference frame, on the basis of the projection of said at least one coordinate of the first set of coordinates on the circumscribed square. |
| US11077370B2 |
Methods for providing access to recordings of game play and generation of custom camera views of the game play
A computer-implemented method is provided. The method includes executing a game application on one or more servers of a data center. The game application is for a game and the game is played by a first user of a first client device remote to the data center. The one or more servers interfaced with one or more encoders for compressing interactive video from the game application responsive to input from the first client device and streaming of the interactive video in a compressed format to the first client device for decompression and rendering to a display of the first client device. The method includes storing, at the data center, a recording of at least part of the game played by the first user using the first client device. The method includes storing, at the data center, state data for at least part of the game played by the first user using the first client device. The method includes generating a replay of the recording responsive to input from a second user device. The replay is generated with a different camera view from a camera view in the recording. The replay is executed using as input the state data. |
| US11077365B2 |
Low latency datagram-responsive computer network protocol
Systems and methods for providing a shared augmented reality environment are provided. In particular, the latency of communication is reduced by using a peer-to-peer protocol to determine where to send datagrams. Datagrams describe actions that occur within the shared augmented reality environment, and the processing of datagrams is split between an intermediary node of a communications network (e.g., a cell tower) and a server. As a result, the intermediary node may provide updates to a local state of a client device when a datagram is labelled peer-to-peer, and otherwise provides updates to the master state on the server. This may reduce the latency of communication and allow users of the location-based parallel reality game to see actions occur more quickly in the shared augmented reality environment. |
| US11077356B2 |
Roller skates
The present invention relates to sports equipment, namely, to roller skates design enabling an athlete to achieve high speed of movement with better comfort and improved motion control, in particular, in case of movement on a lower quality road surfaces. Roller skates consist of two skates—right and left ones, each comprising a spatial rectangular frame with its upper surface adapted to be attached to a frame of the corresponding shoe, either left or right one, and its lower side having two pairs of rollers pivotally attached thereto such that the rollers may rotate being in contact with the roadway and the rollers' axes are parallel to the frame plane, and according to the invention each pair of front and rear rollers of each skate is pivotally attached to the corresponding Z-shaped wheel arm, either front or rear one, which has its central section pivotally attached to the corresponding smaller side of the spatial rectangular frame, and the distance between the axes of the inner rollers of a skate is greater than the distance between the axes of the external rollers. The present invention is aimed to provide such roller skates, which would be more reliable and safe due to increased stability of the skates during movement, also in case of lower quality road surface and during cornering. This objective is achieved by way of creating conditions for uniform distribution of the load arising from the weight of the athlete during movement among all four rollers of each skate, even when moving on a lower quality road surface. |
| US11077353B1 |
Throwing apparatus
A throwing apparatus and method for throwing objects are provided. More specifically, the throwing apparatus features improved arrangement of bearing assembly and location of movable parts which stabilize and improve the performance and accuracy of a throwing apparatus. A throwing arm lever and throwing arm are offset from one another with the bearing assembly disposed therebetween. |
| US11077352B1 |
Tennis ball projecting machine
A tennis ball projecting machine including a support member, a rotatable wheel mounted on one side of the support member, a wheel motor on the other side of the support member, a curved rail below the wheel, a tennis ball hopper above the support member, a surface between the hopper and the machine having a feed opening where at least a portion of the feed opening is on the other side of the support member, and a rotatable body with one or more ball openings that periodically aligns with the feed opening to permit a tennis ball to pass through the feed opening. |
| US11077350B2 |
Tackling machine
It is designed to train athletes in rugby and/or American football, providing movement very close to the actual one and gives possibility to be mounted on scrum machine. Tackling machine comprises supporting frame structure (1) with shape of a parallelepiped and detachable connecting devices interconnect its elements. It is placed on ground (2). The longitudinal guide (6) has forked end and is mounted to the structure (1) through the forward end (61). The forked end (62) of the longitudinal guide goes outside the structure (1). At least one metal rod (8) whose upper end (81) protrudes above the parallelepiped, and carry at least one tensioner (9), connected to the forked end (62). The drive unit (10) is mounted to the fork-shaped longitudinal guide and has a working area arranged outside the structure (1). The tackling dummy (11) is attached to the carrier (12) by a detachable connecting device (13). |
| US11077349B2 |
Ball tee with motorized retrieval
A ball tee with motorized retrieval for re-seating a ball after hitting includes a base having a top surface. A housing is attached to and extends upwardly from the base. The housing has a top wall and an interior surface. The top wall has an aperture extending therethrough to the interior surface. A tether container is positioned within the housing. A tee is attached to and extends upwardly from the top wall. A ball is attached to the tether container by a tether. A driver mechanism is mounted on the interior surface. The driver mechanism is coupled to a drive roller such that the drive roller is rotatable by the driver mechanism. An actuating mechanism actuates a wheel toward the drive roller to engage with the tether and the drive roller. The drive roller rotates to retract the tether into the tether container and reseat the ball. |
| US11077346B2 |
Hockey stick and hockey stick shaft with first and second bends
A hockey stick includes a shaft that includes an upper portion, a lower portion, and a transition portion disposed between the upper portion and the lower portion. The upper portion includes an upper end, where a line that is tangent to the upper end is non-linear with the lower portion and is substantially parallel with the lower portion. A midpoint of the shaft is included in at least one of the lower portion and the transition portion. The hockey stick also includes a blade that extends from the lower portion of the shaft, where a first plane defined by the lower portion and at least a point on the transition portion is generally transverse to a second plane defined by the blade. |
| US11077343B2 |
Monitoring device for a piece of sports equipment
Golf clubs according to at least some example aspects of this disclosure may include a golf club head and a shaft configured to engage with the golf club head which includes a grip engaged with the shaft. Further, the golf club may include a monitoring device, which includes a sensor and a transmitter. Additionally, the monitoring device may be configured to determine data related to the characteristics of a golf swing. Further, the monitoring device may be configured to transmit the data related to the characteristics of a golf swing to a remote computer. |
| US11077341B2 |
Balanced set of golf clubs
A set of golf clubs with a plurality of at least two combinations of different lengths of a minimum of three golf clubs in each combination having progressive lofts that are matched to provide identical swing characteristics requiring unique loft and club length progressions to provide consistent yardage spacing between irons within a combination and between combinations. Each club in a combination is further defined by the shaft having an equal length; an identical swing weight, an identical grip weight and an identical head weight. |
| US11077331B2 |
Direct drive resistance system for exercise machines
A direct drive resistance system for exercise machines having a weighted moment arm that is lifted and lowered by a lifting moment arm and lifting component, which is moved by a force transfer assembly, which is operatively connected to a rotary component of an exercise machine, such that when the exercise machine is activated the force transfer assembly, the lifting moment arm, the lifting component and the weighted moment arm move concurrently to create a resistance force to the motion of the exercise machine. |
| US11077330B2 |
Exercise machine with pancake motor
An exercise machine is disclosed. The exercise machine comprises a pancake motor. The exercise machine comprises a torque controller coupled to the pancake motor. The exercise machine comprises a high resolution encoder coupled to the pancake motor. |
| US11077326B2 |
Harness
The harness includes a belt, a pair of thigh loops and first and second lateral attachment points. At least the first lateral attachment point includes a connector fixed to the belt. The connector is provided with a body defining: at least one pass-through opening inside which an attachment element to the belt passes, a connection ring distinct from the at least one pass-through opening, the connection ring being closed by means of a closing element fitted in removable manner. The closing element and the body define at least one through hole distinct from the at least one pass-through opening and from the connection ring. The closing element separate the connection ring and the at least one through hole. |
| US11077319B2 |
Light therapy spot applicator
Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in a holdable spot applicator assembly, the holdable spot applicator assembly including a reflective surface facing towards a patient and a plurality of LEDs for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are housed within a holdable elongated structure. |
| US11077318B2 |
System and process of utilizing energy for treating biological tissue
A process for heat treating biological tissue includes providing a plurality of energy emitters formed into an array. Treatment energy is generated from the plurality of emitters and applied to target tissue. The treatment energy has energy and application parameters selected so as to raise the target tissue temperature sufficiently to create a therapeutic effect while maintaining an average temperature of the target tissue over several minutes at or below a predetermined temperature so as not to destroy or permanently damage the target tissue. |
| US11077317B2 |
Intravenous radiation treatment method
A method has been invented for intravenously inserting a tumor reduction radiation emitter into the body of a patient suffering from a cancerous tumor. The emitter is very small, yet detectable by medical imaging techniques and guidable by use of magnetism. The emitter is guided through the body by use of a magnet until it is adjacent or in in the tumor itself. The emitter can be oriented in various desired directions by the magnet. The emitter is then wirelessly powered by electrical induction, causing the radiation of a desired wavelength to be directed to tumor cells, causing tumor reduction. |
| US11077316B2 |
Insertion devices and systems for production of emitted light internal to a medium and methods for their use
A system and method for emitting a wavelength of energy internal to a medium or internal to a human or animal subject, and methods for using the system in the treatment of a condition, disorder, or disease. The system includes 1) a source configured to produce an initiation signal penetrating at least a part of the medium or the human or animal subject and 2) an insertion device having an electronics assembly unit. The assembly unit includes 1) an emitter configured to emit the wavelength of energy of a predetermined type to treat a disease or disorder in the human or animal subject or to produce a change in the medium and 2) a receiver that receives the signal. |
| US11077313B2 |
Electricity energy harvesting with liquid crystal-magnetic particle composite particles
A method and apparatus generate electrical currents and/or voltage in tissue using devices composed of liquid crystals and magnetic particles. An instrument applies one or more magnetic fields to the devices to produce electrical energy. |
| US11077311B2 |
Modular defibrillator architecture
Several defibrillators, defibrillator architectures, defibrillator components and methods of operating defibrillators are described. In one aspect, a modular defibrillator architecture is described. A base unit provides a fully functional defibrillator. The functionality of the base unit can be supplemented by attaching an interface unit to the base unit or by connecting a smartphone the base unit. Such devices provide connectivity as well as a screen for displaying supplementary graphics and/or videos which are useful to support both emergency and maintenance & monitoring activities. In some embodiments a battery pack may also or alternatively be coupled to the base unit to prolong the unit's shelf life before recharging or replacement of its batteries is required. If necessary the base unit can be powered from a connected external device such as a mobile communication device. |
| US11077307B2 |
Input switching in a ventricular pacemaker
An intracardiac pacemaker system is configured to produce physiological atrial event signals by a sensing circuit of a ventricular intracardiac pacemaker and select a first atrial event input as the physiological atrial event signals. The ventricular intracardiac pacemaker detects atrial events from the selected first atrial event input, determines if input switching criteria are met, and switches from the first atrial event input to a second atrial event input in response to the input switching criteria being met. The second atrial event input includes broadcast atrial event signals produced by a second implantable medical device and received by the ventricular intracardiac pacemaker. |
| US11077305B2 |
Identification of compromised components in a medical system
In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity. |
| US11077296B2 |
Implant conductor assembly with improved radio frequency properties
In one aspect the invention provides an implant conductor lead assembly which includes an electrode lead, and at least one field target conductor. The field target conductor(s) is located adjacent to the electrode lead to mutually couple the field target conductor to the electrode lead. The electrode lead acts to concentrate electromagnetic fields in the vicinity of the implant conductor assembly towards the field target conductor or conductors. |
| US11077294B2 |
Sheath assembly for catheter pump
In one embodiment, a catheter pump assembly is disclosed. The catheter pump assembly can include an impeller assembly. A catheter body can be coupled with the proximal end of the impeller assembly, the catheter body having a reduced stiffness section disposed proximally of the impeller assembly. A sheath assembly can be configured to be translate over the catheter body relative to the impeller assembly from an impeller assembly delivery position to an impeller assembly deployment position. When the sheath assembly is in the impeller assembly deployment position, a reduction in stiffness is provided between the distal end of the sheath assembly and the impeller assembly. |
| US11077289B2 |
3-dimensional large capacity cell encapsulation device assembly
Disclosed herein are implantable 3-dimensional large capacity device assemblies, specifically, large capacity device assemblies for encapsulating pancreatic progenitor cells for treatment of diabetes. |
| US11077286B2 |
Catheter anchoring device
Embodiments include a catheter anchoring device for securing a percutaneous medical catheter inserted at a skin puncture site to a skin of a body. The catheter anchoring device may include a catheter capture portion coupled to a skin attachment portion. The catheter capture portion may be configured to engage with a portion of the catheter protruding from the skin when the catheter is subcutaneously placed in a body. The skin attachment portion may be configured to adhesively attach the anchoring device to the skin, wherein the skin attachment portion is primarily attached to the skin overlaying and lateral to the subcutaneously located catheter. |
| US11077284B2 |
Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
Ureteral catheters and assemblies are provided including: a drainage lumen including a proximal portion configured to be positioned in at least a portion of a patient's urethra and a distal portion configured to be positioned in a patient's ureter and/or kidney, the distal portion including a coiled retention portion including at least a first coil having a first diameter and a second coil having a second diameter, the first diameter being less than the second diameter; or wherein the retention portion extends radially outwardly from a portion of the distal end of the drainage lumen portion, the retention portion including a proximal end having a first diameter, a distal end having a second diameter, and a wall and/or surface extending therebetween, the retention portion having a second diameter is greater than the first diameter when deployed; or wherein the retention portion includes a plurality of drainage tubes. |
| US11077283B2 |
Methods and systems for providing stimuli to the brain
Visual and auditory stimuli are provided to a patient to treat various neurological disorders or conditions and/or to provide improved mental or physical performance. The visual and auditory stimuli are provided by a wearable headset or sleep mask that may be comfortably worn by a user, such as in bed to induce sleep. The wearable headset or sleep mask is operated by a personal computing device of the user, such as smartphone, having downloaded and active thereon a control application or app for the therapy. The wearable headset or sleep mask also concurrently provides tactile stimuli, and the tactile stimulus is provided from bone conduction transducers that concurrently provides the auditory stimuli. |
| US11077282B2 |
Method and apparatus for humidification of breathable gas with profiled delivery
A humidifying system is configured to humidify pressurized breathable gas. The humidifying system includes a housing configured to couple to a blower that is adapted to supply pressurized breathable gas to provide continuous positive airway pressure (CPAP) treatment to a patient. The humidifying system also includes a tub adapted to hold a volume of water and a heater element to heat the volume of water. A controller is configured to select a humidity profile from a plurality of humidity profiles based on ambient conditions that occurred during a previous treatment session. Each of the plurality of humidity profiles presets a respective target humidity level of the pressurized breathable gas for a respective treatment session. |
| US11077279B2 |
High flow therapy with built-in oxygen concentrator
Apparatus and methods for delivering a heated and humidified mixture of oxygen and air are provided. The apparatus includes an air compressor and oxygen concentrator enclosed in the housing of a vapor transfer system. The air compressor supplies air at a first pressure to a gas inlet. The oxygen concentrator provides oxygen at a second pressure to the gas inlet. The oxygen concentrator and the air compressor are in fluid communication and are configured such that the first pressure of the compressed air and the second pressure of the oxygen are about equal. The apparatus includes a vapor transfer system having a gas passage, a liquid passage having heated liquid and vapor, and a membrane that separates the gas passage and liquid passage. The membrane is positioned to transfer vapor from the liquid passage to the gas passage. |
| US11077276B2 |
Mask assembly
A nasal assembly for delivering breathable gas to a patient includes a frame having an integrally formed first connector portion. A nozzle assembly includes a gusset or base portion and a pair of nozzles. At least one inlet conduit is structured to deliver breathable gas into the frame and nozzle assembly for breathing by the patient. A pair of second connector portions are removably and rotatably connected to respective first connector portions of the frame and are in communication with respective inlet conduits, e.g., directly or via angle connectors. A headgear assembly is removably connected to the pair of second connector portions and/or the angle connectors so as to maintain the frame and the nozzle assembly in a desired adjusted position on the patient's face. |
| US11077272B2 |
Respiratory mask
A respiratory mask for use with a patient, and that is suited for use with children, includes a flexible cushion arranged to interface with and deliver air to the patient's nose. The cushion has a tube connection portion at one or both sides adjacent the patient's nares, the tube connection portion being arranged to connect to an air delivery tube. This location, plus the very low profile of the mask, allows a patient (e.g. an infant) to sleep on their face more comfortably. A more rigid support structure adjacent the cushion is provided to stabilize the cushion and prevent it from collapsing. Headgear is also provided and arranged for releasable attachment to the support structure. |
| US11077271B2 |
Medical apparatus with hypopharyngeal suctioning capability
A laryngeal mask apparatus includes a mask portion, a breathing tube and a suction tube. The suction tube is adapted for connection to a suction-producing device. The suction tube further includes suction ports that suck fluids and secretions from the patient's hypopharyngeal region when suction is created within the interior of the suction tube. The breathing tube is adapted for connection to a ventilating system. Air flows through the breathing tube and into the mask portion. A capillary tube is positioned within the interior of the suction tube. When the mask portion is positioned within a patient's throat and suction is created within interior of the suction tube, the suction ports suck the fluids and secretions in the patient's hypopharyngeal region. At the same time, the suction tube and capillary tube cooperate to provide a stream of air that decreases the direct suction forces on the mucosa of the patient's throat that are caused by the suction ports. The laryngeal mask apparatus includes a scope tube having an interior and an inner tube disposed within the interior of the scope tube. The inner tube is sized for receiving a gastric tube. |
| US11077266B2 |
Method and apparatus to attain and maintain target arterial blood gas concentrations using ramp sequences
An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: —obtaining input of a series of logistically attainable PetX values for a series of respective breaths: —determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths: and—controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath. |
| US11077263B2 |
Disposable ampoule for an aerosol generating device
Disposable ampoule for use in an aerosol generating device, comprising: a medicament container that contains a medicament and is formed of a container body and a container bottom, and a predetermined break point that at least partly surrounds the container bottom, characterised by a collar that surrounds the predetermined break point at its outside and extends the container body over and beyond the container bottom. |
| US11077262B2 |
Mouthpiece assembly, atomizer and electronic cigarette having same
The present disclosure relates to a mouthpiece assembly for an electronic cigarette. The mouthpiece assembly includes a mouthpiece, and a base defining an air inlet. The mouthpiece includes a sucking end, a connecting end, and an air passage. The sucking end defines an air outlet, and the air outlet is in communication with the air passage. The air inlet is in communication with the air passage. The mouthpiece assembly further includes a blocking element on the base. The blocking element is capable of preventing air from flowing through. The blocking element defines at least one through hole. The mouthpiece is capable of driving the blocking element to rotate relative to the base, so that an area of at least one opening formed by the at least one through hole and the air inlet can be changed. |
| US11077260B2 |
Flow control plug securement
A catheter system may include a luer adapter, which may include an outer surface having threading or a recess. The catheter system may also include a flow control plug, which may include a proximal end and a distal end. The proximal end of the flow control plug may include a filter element permeable to air and not to blood. The distal end of the flow control plug may include a cylinder and a taper-shaped luer tip spaced apart from the cylinder. An inner surface of the cylinder may include a protrusion engaged in a snap-fit with the recess or corresponding threading mated with the threading. |
| US11077254B2 |
Embedded multiple-part sensor within a plunger rod to capture and transit injection information
A smart plunger rod adapted to push a medication out of a syringe is disclosed. The plunger rod comprises a shaft sized and dimensioned to act on a piston on the syringe and a finger actuated head portion containing at least two subunits of a wireless sensor. In a pre-activation configuration, the subunits are spaced apart from each other by a physical barrier and the wireless sensor is non-operational. In a post-activation configuration, the subunits are connected to each other and the sensor is operational to send a signal. A user activates the finger actuated head portion to reversibly move the physical barrier and moves the plunger rod from the pre-activation configuration to the post-activation configuration. The signal sent by the sensor comprises information relating to ejecting the medication out of the syringe, and is received by a remote receiver. |
| US11077247B2 |
Intravenous tubing set modified for in-line catheter flushing
An intravenous tubing set is provided having a coupling component for accessing a source of flush solution; a flush chamber; a first IV tubing for delivering saline solution from the source of flush solution to the flush chamber; a first flow control device disposed in the tubing between the source of flush solution and the flush chamber to control the flow of flush solution into the flush chamber; a second IV tubing for delivering flush solution to a patient catheter; and a second flow control device disposed in the second tubing between the flush chamber and the patient catheter. |
| US11077244B2 |
Fluid dispensing device with a flow detector
A portable therapeutic fluid delivery device with a flow detector comprising a heating element and two temperature sensors is presented. Upon activation of the heating element, a flow condition of the fluid inside the delivery tube is determined based on a signal provided by the temperature sensors. A temperature gradient within the therapeutic fluid is detected. The determined flow condition can be one of: air bubbles within the delivery tube, occlusion within the delivery tube, or leakage within the delivery tube. The device can have two parts, for example, a reusable part and a disposable part. Upon pairing of these parts, the heating element and the temperature sensors touch the delivery tube. |
| US11077243B2 |
Devices, systems, and methods for estimating active medication from injections
One or more embodiments relate, generally, to a reusable accessory for a medication injection pen. Such a reusable accessory may be adapted to be reversibly attached to a medication injection pen, and configured to detect an event associated with an injection of medication from the medication injection pen. It may also be configured to determine a percentage of medication that remains active for injection by the medication injection pen based on timing information and dosing event information. |
| US11077242B2 |
Blinding cap for rigid needle shield and related syringe assembly
A blinding cap for covering a rigid needle shield that is covering a needle of a syringe includes an elongated body extending between a proximal end and an opposing distal end, the body at least partially bounding a chamber. An annular sleeve projects from the proximal end of the body and at least partially bounds a channel. A first flange radially inwardly projects from the body into the chamber, the first flange at least partially bounding an opening that provides communication between the chamber and the channel. |
| US11077237B2 |
Constant pressure syringe for surgical use
A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient. |
| US11077236B2 |
Powered lavage handle and associated use therefore
A lavage handle for facilitating at least one of an irrigation function and a suctioning function at a target zone preferably includes a portable body, a power-operated fluid-displacing mechanism in communication with said body wherein said fluid-displacing mechanism has one of a first operating mode for inducing outward irrigation of fluid towards the target zone and a second operating mode for inducing inward suction of fluid from the target zone. An actuation mechanism is located at said body and operable communicated with said fluid-displacing mechanism such that said fluid-displacing mechanism is selectively operated in at least one of said first operating mode and said second operating mode. The actuation mechanism may include an irrigation-inducing mechanism and/or a suction-inducing mechanism. |
| US11077233B2 |
Pharmaceutical and other packaging with low oxygen transmission rate
Processing an evacuated blood sample collection tube or other vessel by plasma enhanced chemical vapor deposition to apply a tie coating or layer (289), a barrier coating or layer (288), and optionally one or more additional coatings or layers. The tie coating or layer of SiOxCy is applied under partial vacuum and, while maintaining the partial vacuum unbroken in the lumen, the barrier coating or layer is applied. Then optionally, while maintaining the partial vacuum unbroken in the lumen, a pH protective coating or layer of SiOxCy can be applied. As a result of this processing, a coated vessel is produced having a lower gas permeation rate constant into the lumen than a corresponding vessel made by the same process except breaking the partial vacuum in the lumen between applying the tie coating or layer and applying the barrier coating or layer. Retention features are also described for keeping the vessels stoppered during exposure to reduced ambient pressure. |
| US11077232B2 |
Methods and polymer compositions for treating retinal detachment and other ocular disorders
The invention provides methods and polymer compositions for treating retinal detachment and other ocular disorders, where the methods employ polymer compositions that can form a hydrogel in the eye of a subject. The hydrogel is formed by reaction of (i) a nucleo-functional polymer that is a biocompatible polymer containing a plurality of thio-functional groups —R1—SH wherein R1 is an ester-containing linker, such as a thiolated poly(vinyl alcohol) polymer and (ii) an electro-functional polymer that is a biocompatible polymer containing at least one thiol-reactive group, such as a poly(ethylene glycol) polymer containing alpha-beta unsaturated ester groups. |
| US11077225B2 |
Hollow porous spherical particle artificial bone as well as preparation method and application thereof
The disclosure provides a preparation method of a hollow porous spherical particle artificial bone. The method comprises: (1) uniformly mixing bioceramic powder, bioglass powder and an excipient to obtain a solid-phase mixture, then adding binder solution to the solid-phase mixture, and uniformly mixing to obtain a plastic wet material; (2) loading a plastic wet material into an extrusion device of an extrusion rounder to be extruded by the orifice plate of the extrusion device to form a strip-shaped material; (3) putting the strip-shaped material into the spheronization device, cutting, and then spheronizing to form spherical particles; and (4) placing the spherical particles into a furnace, debinding, removing the excipient and the binder, and then sintering at 750-1550° C. |
| US11077224B2 |
Ostomy device
Disclosed is an ostomy device with an adhesive wafer for attachment to a skin surface (S) of a user and a collecting bag (8) or collecting output from a stoma. The collecting bag is connected to the adhesive wafer, and the adhesive wafer has a through-going hole (6) for accommodating the stoma (7) of the user. The adhesive wafer includes a backing layer (3), a first switchable adhesive composition (2), a second absorbent adhesive composition (1), and a release liner, and the second adhesive layer has a central portion with a first thickness and an edge portion with a second thickness, the first thickness being larger than the second thickness. |
| US11077218B1 |
Payment terminal sanitizing device
A payment terminal sanitizing device includes a housing having a base member configured to removably secure to a payment terminal. The base member includes tabs and slots that engage corresponding tabs and slots on the payment terminal. A top cover is removably secured to the base member. The sides of the top cover and base member curve outwardly to form an interior volume between the top cover and base portion. The interior volume includes a plurality of brackets configured to support individual UV lights that are positioned on opposing sides of the interior of the housing. The UV lights are operably connected to a power source, such as a wall outlet, for example. The UV lights are oriented such that they illuminate or irradiate the input mechanisms of the payment terminal, in order to prevent the spread of germs between individual users of the payment terminal. |
| US11077215B2 |
Co-expression of magnetotactic bacterial genes and genes encoding iron handling proteins in cells
The invention provides an improved modified magnetosome that contains more iron therein with the combination of the expressed genes. This is achieved by co-expression of (a) one or more bacterial magnetotactic genes to amplify iron uptake, compartmentalization and biomineralization in cells, with (b) one or more mammalian iron handling proteins that together augment(s) and/or regulate the cells iron pool. As a result, mammalian cells or bacterial cells that are transfected or transformed, respectively, can be more effectively tracked using various imaging technologies. |
| US11077206B2 |
Composition for gene therapy or transfection, and preparation method and use thereof
A composition for gene therapy or transfection includes nucleic acid, natural polyphenol, and cationic molecules. There are several phenolic hydroxyl groups in the natural polyphenol, so as to eliminate free radicals, prevent cancer, fight inflammation, and provide antioxidants feature. Compared with the delivery of cationic molecules alone, the composition can significantly improve the transfection efficiency by about 60-70%, reduce the dose of effective transfection of cationic molecules by about 20 times, thereby reducing the toxicity of transfection and showing better organism compatibility. The composition of the present invention does not introduce other chemical reagents, does not require synthesis, has high biosafety, and can efficiently and safely deliver a plurality of nucleic acid molecules into cells. The composition can be used as a highly effective and low-toxicity nucleic acid drug in the treatment of gene-related diseases, and has good medicinal value. |
| US11077203B2 |
Anti-SEZ6 antibody drug conjugates and methods of use
Provided are novel anti-SEZ6 antibodies and antibody drug conjugates, and methods of using such anti-SEZ6 antibodies and antibody drug conjugates to treat cancer. |
| US11077201B2 |
Immunoconjugates with an intracellularly-cleavable linkage
The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a therapeutic moiety, and further relates to processes for making and using the conjugates. |
| US11077198B2 |
Pegylated carfilzomib compounds
The present invention provides a method of treating multiple myeloma using polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula I wherein R1, R2, linker, PEG, n and o are as defined herein. |
| US11077194B2 |
Nitric oxide releasing pharmaceutical compositions
The present invention generally relates to nitric oxide releasing pharmaceutical compositions and methods of using the same. |
| US11077183B2 |
CD40 ligand fusion protein vaccine
Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described. |
| US11077178B2 |
Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use
A chimeric antigen receptor is disclosed that includes: (a) an scFv comprising a light chain variable domain (VL) and a heavy chain variable domain (VH), wherein the scFv specifically binds to CCR4; (b) a hinge and transmembrane domain from CD8; (c) an intracellular 4-1BB signaling domain; and (d) an intracellular CD3 zeta signaling domain, wherein (a)-(d) are in N to C terminal order. Uses of the chimeric antigen receptor, such as for treating a malignancy, are also disclosed. |
| US11077159B2 |
Compositions from halophyte plants and methods of use thereof
The invention relates to skin care compositions comprising an ethanol extract obtained from the leaves and/or stems of Arthrocnemum macrostachyum and/or Tetraena sp. cf. mandavillei. In addition, the invention relates to methods for treating a skin condition, reducing the risk of developing a skin condition, for treating wounds, for reducing and/or delaying the effects of aging of skin, and/or for treating and/or reducing inflammation of skin by administration of skin care compositions of the invention. |
| US11077148B2 |
Acellular biologic composition and method of manufacture
A biological composition has a mixture of mechanically selected allogeneic biologic material derived from placental tissue. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function. |
| US11077143B2 |
Elimination of PD-L1-positive malignancies by PD-L1 chimeric antigen receptor-expressing NK cells
Provided herein are compositions of NK-92™ cells that express a combination of PD-L1 CAR, CD16 and IL2, and the method of using these cells to reduce tumor cells and cells in tumor microenvironment (e.g., MDSCs or TAMs) and treat cancer. |
| US11077142B2 |
Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
| US11077138B2 |
Methods of tissue repair and regeneration
The disclosure provides local delivery of a trace element to a site of tissue injury, which triggers the body' inherent tissue repair mechanism. Local delivery of copper to the site of injury induces migration (i.e., homing) of stem cells to the site of injury, triggers differentiation of stem cells at the site of injury, induces tissue regeneration at the site of injury, induces signaling molecules that trigger tissue regeneration, reverses damage at the site of injury, and/or reconstructs the microenvironment of neurofibril cells and neurosecretory cells at the site of injury. In another aspect, delivering a trace element (for example, copper) directly to the site of injury and associated methods are disclosed. |
| US11077136B2 |
Compositions for the skin
The present invention relates to a composition comprising hyaluronic acid, dermatan sulfate, at least one omega-3 fatty acid, and at least one nucleotide. It also relates to the new composition for use in the treatment or prevention of diseases, ailments, dysfunctions, or alterations of the skin, preferably atopic dermatitis. The composition may be in the form of a pharmaceutical composition, food supplement, functional food, or medical food. |
| US11077127B2 |
Adjuvant containing baicalin, particularly from a Scutellaria baicalensis extract, and animal feed containing such an adjuvant
The invention relates to a nutritional adjuvant, comprising baicalin and/or baicalein diluted on a medium, and to a feed comprising such an adjuvant, for improving production performance in farm animals in stressful situations. |
| US11077125B2 |
Ophthalmic composition containing sulfasalazine and hyaluronic acid
An ophthalmic composition containing sulfasalazine and hyaluronic acid is disclosed. |
| US11077124B2 |
Pharmaceutical compositions
A pharmaceutical composition for inhalation comprising R (+) budesonide and one or more bronchodilators, and, optionally, one or more pharmaceutically acceptable excipients is described. |
| US11077123B2 |
Use of bile acids and bile salts as anti bacterial agents for inhibition of bacterial conjugation and horizontal gene transfer
Methods of inhibiting bacterial conjugation, bacterial horizontal gene transfer or bacterial growth are disclosed. The methods comprise contacting bacteria with an effective amount of a bile acid or a bile salt, wherein the effective amount does not affect viability of the bacteria. A method of increasing susceptibility of bacteria to antibiotic treatment is also disclosed as well as methods of decontaminating a farm animal housing or a medical surface and methods of treating water. Also disclosed are compositions effective in inhibiting bacterial conjugation, bacterial horizontal gene transfer and bacterial growth. |
| US11077120B2 |
Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto
The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflammation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof. |
| US11077118B2 |
Methods and compositions for ibogaine treatment of impulse control disorder, anxiety-related disorders, violence and/or anger, or regulating food intake
This invention provides a method for treating anxiety-related disorder or impulse control disorder, regulating food intake, attenuating food cravings, or treating anger and/or violence and disorders associated therewith in a patient, comprising administering to the patient in need thereof a therapeutically effective amount of ibogaine, ibogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof. |
| US11077115B2 |
Rorgamma modulators and uses thereof
The present invention provides novel compounds of formula (Ia) that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases. |
| US11077110B2 |
Compositions and methods for treating and preventing metabolic disorders
Provided herein are compositions and methods for treating or preventing metabolic disorders. In particular, provided herein are compositions, methods, and uses of Cyclin-dependent Kinase 6 (CDK6) inhibitors for treating and preventing metabolic diseases (e.g., type II diabetes, obesity, metabolic syndrome, elevated blood pressure, cardiovascular diseases, elevated fasting plasma glucose, and high serum triglycerides). |
| US11077107B2 |
Triazolopyrazine
Disclosed are compounds of the formula (I) wherein the groups R1 to R3 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament. |
| US11077100B2 |
Tetrahydroquinoline derivatives as P2X7 receptor antagonists
The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the P2X7 receptor. |
| US11077099B2 |
Oral tablet formulation of lenalidomide
The present disclosure relates to an oral tablet composition comprising lenalidomide and a method for preparing the same. More particularly, the present disclosure relates to a tablet-type composition and a method for preparing the same wherein the composition exhibits physicochemical equivalence with lenalidomide preparations of hard capsules, has the same pharmacological, therapeutic effect in non-clinical studies and bioequivalence studies, and also has improved ease of taking, handling, safety and the like. |
| US11077095B2 |
Methods for treating neurodegenerative disorders
Methods of treating a disease characterized by amyloid aggregates are provided herein. |
| US11077094B2 |
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed. |
| US11077092B2 |
Methods of treating diabetes by administering a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor
Use of a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor for the treatment of diabetes and related conditions is disclosed. |
| US11077090B2 |
Compounds and compositions and uses thereof
Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need thereof are also disclosed. |
| US11077087B2 |
Compositions comprising dihydroquercetin for use in methods for treating herpes
Disclosed is the use of a composition including dihydroquercetin and optionally α-tocopherol and/or bisabolol for treating herpes infection. Also disclosed is the use of such a composition for treating inflammation induced by herpes infection in mucosa, as well as a method for treating HSV infection and the associated inflammation. |
| US11077083B2 |
Oils with anti-inflammatory activity containing natural Specialized Proresolving Mediators and their precursors
The present invention encompasses oils that have anti-inflammatory or resolution-stimulating activity that contain or are enriched with Specialized Proresolving Mediators (SPM) or SPM precursors, which originate from an oil obtained from organisms containing long chain omega-3 polyunsaturated fatty acids, such as fish, crustaceae, algae, and mollusks. The invention also encompasses a method for the production of these oils, and the utilization of the oils for nutritional supplements, pharmaceutical formulations, and cosmetic formulations, which can be employed for treating an inflammatory condition. |
| US11077081B2 |
Amino-acid-containing composition for enhancing recovery from muscle fatigue
Administering an amino acid-containing composition, containing the following amino acids (1)-(9), wherein the molar content ratio of each amino acid to the total content of the amino acids (1)-(9) falls within the following numerical ranges: (1) leucine 35-66%; (2) isoleucine 5.0-15%; (3) valine 5.0-15%; (4) threonine 7.0-14%; (5) lysine 8.0-16%; (6) methionine 2.0-10%; (7) histidine 0.1-3.5%; (8) phenylalanine 2.5-8.0%; and (9) tryptophan 0.1-2.0%, is effective for enhancing recovery from muscle fatigue. |
| US11077080B2 |
Use of anti-connexin agents for modulating the therapeutic effect of psychotropic drugs
The invention first relates to a product containing at least one connexin-blocking agent and a psychotropic drug as combination products for use simultaneously, separately, or spread over time in patients suffering from psychiatric and/or neurodegenerative disorders. The connexin-blocking agent is advantageously selected from the group comprising meclofenamic acid, 18-β-glycyrrhetinic acid, carbenoxolone, mefloquine, and 2-APB, and preferably consists of meclofenamic acid. The invention first relates to a product containing at least one connexin-blocking agent and a psychotropic drug as combination products for use simultaneously, separately, or spread over time in patients suffering from psychiatric and/or neurodegenerative disorders. The connexin-blocking agent is advantageously selected from the group comprising meclofenamic acid, 18-β-glycyrrhetinic acid, carbenoxolone, mefloquine, and 2-APB, and preferably consists of meclofenamic acid. |
| US11077076B2 |
Pharmaceutical composition
A pharmaceutical composition is described. The composition comprises: (i) a drug component comprising at least one salmeterol compound selected from salmeterol and the pharmaceutically acceptable derivatives thereof; and (ii) a propellant component comprising 1,1-difluoroethane (HFA-152a). |
| US11077072B2 |
Binge behavior regulators
Methods and compositions utilizing 2-aminoindan derivatives collectively represented by Formula I as described and defined in the specification for regulating binge behavior, particularly binge drinking, are disclosed. |
| US11077071B2 |
Phytonadione compositions and related methods
Stable Phytonadione compositions for parenteral administration are provided which comprise (E) isomer of phytonadione at or greater than 97% w/w as the active ingredient, and is substantially free of (Z) isomer. Said compositions are stable, sterile, and particulate-free. Further, said compositions reduce or avoid allergic reactions to benzyl alcohol and polysorbate. In some aspects, the compositions are free or substantially free of benzyl alcohol and/or reduced amounts of polysorbate. Methods of manufacture and methods of administration also provided. |
| US11077067B2 |
Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen
Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions comprising Ibuprofen using solventless mixing methods. Excess coating material that is not bound to coated Ibuprofen may be removed by a sieving process. Coating and dosing ratios can also be optimized to minimize the amount of excess unbound coating material. Additionally, the compositions can be formulated to preserve the functional coating of coated Ibuprofen and to minimize aeration of Ibuprofen when mixed into suspension. |
| US11077063B2 |
Apparatus and method for cryogranulating a pharmaceutical composition
Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium. Methods of cryogranulating the pharmaceutical substance in the fluid medium are also provided. In particular embodiments, the dispenser assembly is used with suspensions or slurries of pharmaceutical compositions including biodegradable substances, such as proteins, peptides, and nucleic acids. In certain embodiments, the pharmaceutical substance can be adsorbed to any pharmaceutically acceptable carrier particles suitable for making pharmaceutical powders. In one embodiment, the pharmaceutical carrier can be, for example, diketopiperazine-based microparticles. The dispenser assembly improves the physical characteristics of the cryopellets formed and minimizes product loss during processing. |
| US11077062B2 |
Pharmaceutical composition
An object of the present invention is to provide a pharmaceutical composition which has excellent stability, disintegratability, and absorbability, is easily prepared, and contains 4-(2-fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide or a pharmaceutically acceptable salt thereof and a cyclodextrin derivative. The present invention relates to a pharmaceutical composition containing 4-(2-fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide or a pharmaceutically acceptable salt thereof and hydroxypropyl-β-cyclodextrin. |
| US11077060B2 |
Chitin-glucan complex, its preparation, and uses
A biocomposite powder comprising 20-95% (w/w) chitin-glucan complex (CGC), and up to 50% (w/w) mannose-containing polysaccharides, wherein the biocomposite powder has a bulk density of 0.5 to 1.0 g/cm3, and wherein greater than 60% (w/w) of the particles of the biocomposite powder have a size below 212 μm. |
| US11077057B2 |
Polymer-grafted nanobins
Provided herein are small unilamellar vesicles with surface-displayed polymer moieties, and methods of use and manufacture thereof. In particular, provided herein are polymer-grafted nanobins, and methods of drug delivery therewith. |
| US11077054B2 |
Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia
The present invention recognizes that medical devices, such as but not limited to contact lenses, can be made having a coating made at least in part using printing technologies to provide drug storage and drug release structures. The coating preferably includes at least one drug reservoir layer and a least one barrier layer, and can include structures, such as but not limited to capillary structures that alone or in combination modulate the release of the drug from the coating. One aspect of the present invention is a medical device that incorporates a drug in at least one coating. |
| US11077051B2 |
Shear-thinning therapeutic composition, and related methods
A shear-thinning therapeutic composition is provided along with methods of making and using the therapeutic composition. |
| US11077044B2 |
Compositions that brighten skin, provide sun protection, and permit vitamin D production
The present invention relates to sunscreen compositions. More specifically, the present invention relates to sunscreen compositions that, when applied to the skin, prevent sun damage while allowing the passage of sufficient UVB in the range of 290 nm-298 nm to produce vitamin D, while also inhibiting melanogenesis. |
| US11077042B2 |
Liquid hair dye composition
A liquid hair dye composition comprising the following components (A) and (B), wherein the content (X) of the component (A) in the composition is 1.5 mass % or more and 5.16 mass % or less, the content (Y) of the component (B) in the composition is 9 mass % or more and 98.5 mass % or less, the composition satisfies the following equation (1) (with a proviso that a composition in which the diol content is 50 mass % or more and the water content is 2 mass % or less in the liquid hair dye composition is excluded). Y≥22.75X−22.75 (1) (A) an azo dye represented by the following formula (A-2) (B) a monoalcohol and/or a diol other than alkanolamines |
| US11077038B2 |
Cosmetic shampoos with low water content in a pouch
The present disclosure relates to a cosmetic product cleaning and care of the keratinous, fibres, in particular human hair, comprising (i) a pouch, comprising at least one sealed chamber, wherein the sealed chamber has at least one wall made from a water-soluble foil, and (ii) a shampoo composition, which is present in the sealed chamber of the pouch, wherein the shampoo composition contains—relative to its total weight (iia) from about 0 to about 20 wt % water (iib) at least one anionic tenside and (iic) at least one cationic tenside. |
| US11077036B2 |
Lactam solubility
Compositions comprising a lactam and an alkyl lactate. The compositions are suitable for use as anti-microbial, anti-biofilm and bacteriostatic compositions. |
| US11077035B2 |
Hair treatment compositions and methods
The present invention is directed to the hair care treatment compositions, including pre- and post-treatment compositions, containing select aryl alkanone compounds as quenching and/or chelating agents. |
| US11077034B2 |
Care conditioner with a low water content in a pouch
The present disclosure relates to a product for care of keratinic fibers, in particular human hair, comprising a bag (pouch) comprising at least one sealed chamber, wherein the sealed chamber comprises at least one wall of one water-soluble film, and a conditioner composition which is in the sealed chamber of the bag (pouch) wherein the conditioner composition contains, based on its total weight (iia) from about 0 to about 20 wt % water and (iib) at least one fatty ingredient from the group of C8-C30 fatty alcohols and C8-C30 fatty acid triglycerides. |
| US11077031B2 |
Oil-in-water emulsion composition
The present invention relates to: an oil-in-water emulsion composition having a viscosity of 1,500-50,000 cps, and comprising an anionic surfactant and a sugar surfactant so as to satisfy the following relational expression 1; and a cosmetic composition containing the same. [Relational expression 1] 0.01≤A/B≤1 (In relational expression 1, A is the wt % of the anionic surfactant, and B is the wt % of the sugar surfactant, wherein the wt % of each ingredient is based on the total weight of the composition, and B is 1-30 wt %.) |
| US11077027B2 |
Automatic pacing system for a baby bottle
A baby bottle, an insert for a baby bottle, a baby bottle including an insert, and a method of feeding an infant that serves to pace the infant's feeding rhythm. Generally, these devices and methods will be of use for a preterm infant who lacks coordination of the suck-swallow-breathe synchrony, but can also be used with full term infants who can benefit from rigid control of the flow of milk from a bottle, this includes, but is not limited to, infants with gastroesophageal reflux who can require pacing of feeds to allow for gastric emptying. The device generally cues the infant to swallow and breathe after each 1-4 sucks by stopping the flow of the fluid from the bottle after the infant has sucked sufficiently or a predetermined period of time has passed. Once the baby breathes or a period of time passes, the bottle resets for the next repetition. The device also serves to consistently slow the flow of milk during oral feeding. |
| US11077026B1 |
Medication dispenser
This invention relates to a lockable, tamper resistant medication dispenser for medications with abuse potential and for monitoring medication compliance. The medication dispenser is programmed to dispense a specified dose of medication at a specified interval. The medication chamber of the dispenser is filled by the pharmacist and locked before being dispensed to the patient. This prevents direct access to the medication by the patient. The medication is dispensed to the patient dissolved in a large volume of liquid to prevent intravenous and intranasal abuse and diversion. The medication dispenser is equipped with biometric access control to prevent diversion. It can be equipped with a self destruct mechanism when tampered with and have the ability to record video of the actual ingestion of the medication infused liquid by the patient for subsequent analysis. |
| US11077018B2 |
Bathing system and method of controlling same
A bathing system includes a vessel, an air blower, and a steam generator. The vessel comprises an inlet. The air blower is fluidly coupled to the inlet by a conduit, and is configured to provide a flow of air to the conduit. The steam generator is fluidly coupled to the conduit upstream of the inlet, and is configured to provide steam to the conduit to create a mixture of steam and air in the conduit. The air blower is further configured to direct the mixture of steam and air to the vessel. |
| US11077012B2 |
Health-regain device and system thereof
A health-regain device, includes a driving portion, a health portion disposed on one side of the driving portion, and a control module communicably connected to the driving portion, wherein the control module controls the driving portion driving the health portion in rhythmic reciprocating motion. |
| US11077005B1 |
Patient isolation system and method
A portable, protective enclosure for coupling to a patient support includes a collapsible frame, a canopy drape, a pair of gloves and sleeves configured for receiving hands and arms of a user, and a zipper disposed along one of the side surfaces of the drape, wherein the side surface is not folded about itself when the zipper is in an open state. A pair of filters are disposed on opposing sides of one of the side surfaces of the canopy drape, the filters together providing high efficiency particulate air filtration for at least 99.97% of airborne particulate 0.3 microns in diameter. Gas-permeable media is provided for air intake. A fan in communication with the first and second filters is provided for creating negative pressure in the internal region of the canopy drape, the fan configured to evacuate air from the internal region. A negative pressure indicator also is included. |
| US11077000B2 |
Track assembly
A track assembly for mounting a movable object includes a track having a web and at least one flange joined with the web. A stop assembly is mounted to the track at the web by a releasable connection and configured to engage the flange to form a moment restraint for the connection of the stop assembly to the web. |
| US11076999B2 |
Absorbent articles and methods of making
Described herein are absorbent articles and methods of making such articles. The articles are made by bonding a copolymer onto a substrate to form a core. The absorbent articles are particularly useful in personal care product, e.g., disposable hygiene products. |
| US11076996B2 |
Bandages for supplying ozone therapy
The present disclosure relates to a bandage wherein the bandage comprise of a first layer of protective covering, wherein the first layer is removable; a second layer of covering, wherein the second layer of covering is made of a cloth material; a third layer of covering, wherein the third layer is the top most layer of the bandage and together with the second layer forms a support pad; an injector, wherein the injector is present on the second layer of covering; a cylinder, wherein the cylinder is present in the support pad, wherein the bandage is used for delivering a medication to a localized area on a patient's body. The bandage is further used for delivering localized, painless ozone gas treatment to a patient suffering from infectious disease. The bandage is easy to carry and comes in various shapes and sizes. |
| US11076995B2 |
Cold-drawn polyolefin copolymers cord for earplug
An earplug assembly and method of forming the same is described. The method includes uniaxially stretching a cord formed of copolymer including ethylene segments and vinyl acetate segments to form a cold-drawn cord. The cold drawn cord has an elongation to break of 250% or less. The method then includes fixing the cold drawn cord to an earplug. |
| US11076991B2 |
Low voltage communication between subsystems in a laser eye surgery system
A laser eye surgery system comprises subsystems which communicate with one another through low voltage differential signaling (LVDS). The laser eye surgery system may comprise a first subsystem interface, including an LVDS driver or transmitter coupled to and in communication with an LVDS receiver of a first subsystem of the laser eye surgery system. The first laser eye surgery subsystem itself may comprise an LVDS transmitter coupled to and in communication with an LVDS receiver to return data to the first subsystem. Further laser eye surgery subsystems may also include the same arrangement of drivers and receivers with respective subsystem interfaces. LVDS lowers power consumption and the risk of error in communication between laser eye surgery systems, leading to safer and more reliable surgical procedures performed. |
| US11076989B2 |
Ocular treatment devices and related methods of use
Apparatus and methods for ocular treatment are provided. The apparatus can comprise a microcannula having a proximal end, a distal end, a cavity, and a central longitudinal axis. The apparatus can include a handle coupled to the proximal end of the microcannula. The apparatus can include multiple orifices extending circumferentially about the microcannula distal end, each of the orifices defining a channel extending transverse to the central longitudinal axis, and one or more grooves about a circumference of the microcannula. |
| US11076988B2 |
Enhancing performance of a capsulotomy device
The present disclosure provides a capsulotomy device having a unique insertion sleeve configuration comprising beveling and two notches at the distal end of the insertion sleeve. The unique configuration assures that the motion the capsulotomy loop comprising the heating element goes through during deployment from and retraction into the insertion sleeve is minimized and predictable. |
| US11076987B2 |
Device and method for treatment of retinal detachment and other maladies of the eye
The present invention includes a device for effecting deformation of a sclera of an eye, including an expandable, mesh tube having holes dispersed through an entire surface thereof and with first and second tapered ends, and inserted unexpanded to deform the sclera when expanded. A central portion is intrascleral, with the first and second tapered ends external to the sclera on top of an intact scleral surface to deform during expansion, and simultaneously causes the sclera to be deformed so that the sclera moves towards the inside of the eye while simultaneously causing the sclera to move towards the outside of the eye. The mesh tube includes struts, connecting points of the struts are of different sizes, the first and second tapered ends and the connecting points within the tapered ends are thicker than the connecting points of the mesh tube, and the mesh tube includes fixation tabs. |
| US11076986B2 |
Electronic drop dispensing device and method of operation thereof
Disclosed is a portable automatic electronic drop administration device and method of operation thereof. The device comprises a microcontroller communicatively coupled to at least an accelerometer and an electromechanical assembly to administer one or more drops of a liquid, semi-liquid or gaseous substance from any flexible container held within. The device detects whether it is in a suitable orientation before automatically self actuating the electromechanical assembly to administer one or more drops. It can be used in a variety of settings including self administration of eye drops, dispensing condiments or precise metering of liquid medications. Additionally, the device may contain sensors and wireless components to track usage and event data that may be communicated to a physician or other healthcare provider remotely. |