最新美国发明专利第2021-07-13期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US11060096B2	RNA-based compositions and adjuvants for prophylactic and therapeutic treatment The present invention is directed towards an artificial RNA nanostructure comprising multiple external strands of RNA, each external strand comprising about 40-50 nucleotides; one internal strand of RNA comprising more than about 50 nucleotides; the internal strands and external strands assembled to form a triangle nanostructure, a square nanostructure, or a polygon nanostructure and a pRNA three-way junction (3WJ) motif at each vertex of the nanostructure. Such nanostructure can be provided in a composition together with an adjuvant for use in inducing the production of high affinity neutralizing antibodies or inhibitory antibodies, inducing the production of cytokines, inducing an immune response in a subject, or a combination thereof.
US11060095B2	Method for isolating cross-reactive aptamer and use thereof The subject invention provides a SELEX strategy for isolating cross-reactive aptamers that recognize a core structure of a small-molecule family and bind to several structurally-similar molecules in the family. The subject invention also provides methods, assays, and products for detecting small-molecule targets of the family in a sample in both clinical and field settings. Such method is based on an aptamer sensor that reports the presence of small-molecule targets via a sensitive colorimetric signal for naked-eye detection. The subject invention further provides exonuclease-based methods for generating structure-switching aptamers from fully folded aptamers and developing electrochemical aptamer-based (E-AB) sensors for rapid and sensitive detection of synthetic cathinones.
US11060092B2	Inhibitors of cytoplasmic histone deacetylase 4 complex for treating or preventing vascular or valve calcification A pharmaceutical composition and a method of treating, reducing or preventing vascular, cardiovascular arterial or valve calcification in a subject in need comprising administering to the subject an effective amount of an agent that prevents or reduces the expression of HDAC4, an agent that modulates the location of HDAC4, an agent that binds to HDAC4 or an inhibitor of HDAC4 or any combination thereof is provided. In some embodiments, there is provided a pharmaceutical composition comprising: an agent that prevents or reduces the expression of HDAC4, an agent that modulates the location of HDAC4, an agent that binds to HDAC4 or an inhibitor of HDAC4 or any combination thereof; an agent that prevents or reduces the expression of SIK or is an inhibitor of SIK; and/or an agent that prevents or reduces the expression of ENIGMA (Pdlim7) or is an inhibitor of ENIGMA.
US11060089B2	Antisense oligomers and methods of using the same for treating diseases associated with the acid alpha-glucosidase gene The present disclosure relates to modified antisense oligonucleotides. The nucleotides described herein are of 10 to 40 nucleobases and include a targeting sequence complementary to a target region within intron 1 of a pre-mRNA of the human alpha glucosidase (GAA) gene. The target region includes at least one additional nucleobase compared to the targeting sequence, wherein the at least one additional nucleobase has no complementary nucleobase in the targeting sequence, and wherein the at least one additional nucleobase is internal to the target region.
US11060086B2	Transposition of nucleic acids into eukaryotic genomes with a transposase from heliothis The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and transposases that further improve expression. Further disclosed are vectors that can be used in a gene transfer system for stably introducing nucleic acids into the DNA of a cell. The gene transfer systems can be used in methods, for example, gene expression, bioprocessing, gene therapy, insertional mutagenesis, or gene discovery.
US11060084B2	SH3 domain derivatives The present invention is directed to SH3 domain derivatives having a specific binding affinity to a target molecule. In this respect, the invention provides SH3 domain derivatives of nephrocystin (NPHP1) and the Tec kinase. The invention also provides a method for the production of a library comprising recombinant derivatives of NPHP1 or the Tec kinase SH3 domains and a method for selecting from the library one or more derivatives of the SH3 domain of nephrocystin (NPHP1) or the Tec kinase having a specific binding affinity to a target molecule.
US11060083B2	Methods and compositions for producing double allele knock outs The present invention provides a method and compositions utilizing the CRISPR system to disrupt a target gene in eukaryotic cells to produce double allele knock outs. The method finds use in producing afucosylated antibodies with enhanced ADCC activity.
US11060081B2	Specimen pretreatment apparatus, specimen pretreatment cartridge, and specimen pretreatment method Disclosed is a specimen pretreatment apparatus comprising: a specimen container holder configured to hold a specimen container for containing a plasma specimen; a reagent container holder configured to hold a first reagent container for containing a first reagent including magnetic particles on which a nucleic acid in the plasma specimen is adsorbed; a reaction unit in which a plurality of reaction containers are disposed, the reaction unit being configured to accelerate, in each reaction container, reaction of the plasma specimen and the first reagent; a washing unit in which a washing container is disposed, the washing unit including a magnetic force applying portion configured to apply magnetic force to the washing container; a dispensing unit; and a controller programmed to control the dispensing unit to: dispense the plasma specimen contained in the specimen container and the first reagent into the plurality of reaction containers in the reaction unit; dispense a mix liquid of the plasma specimen and the first reagent from each of the plurality of reaction containers into the washing container; and remove a liquid component from the washing container while the magnetic particles contained in the discharged mix liquid is attracted by the magnetic force applying portion.
US11060080B2	Method for fermentation-production of pentanediamine comprising carbon dioxide stripping technique A method for fermentation-production of a pentanediamine, comprising: culturing a cell expressing a lysine decarboxylase to obtain a whole cell fermentation broth comprising a pentanediamine; and extracting the pentanediamine from the whole cell fermentation broth, and striping the whole cell fermentation broth of carbon dioxide contained therein before adding a strong base. The method greatly increases a production volume of the pentanediamine.
US11060075B2	Engineered DNA polymerase variants The present invention provides engineered DNA polymerase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered DNA polymerase polypeptides. The invention also provides methods for use of the compositions comprising the engineered DNA polymerase polypeptides for diagnostic and other purposes.
US11060073B2	Bacteria engineered to treat diseases associated with hyperammonemia Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating disorders associated with hyperammonemia are disclosed.
US11060072B2	Engineered imine reductases and methods for the reductive amination of ketone and amine compounds The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
US11060071B2	Increased biosynthesis of benzylisoquinoline alkaloids and benzylisoquinoline alkaloid precursors in a recombinant host cell Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductases thereby increasing the production of benzylisoquinoline alkaloids and/or benzylisoquinoline alkaloid precursors.
US11060065B2	Tissue structure and preparation method thereof A tissue structure for enabling comprehensive understanding of gene patterns of mature cells and a method of preparing the tissue structure are provided. A tissue structure is obtained by co-culturing an endodermal, ectodermal, or mesodermal cell derived from a stem cell and at least one cell and/or factor selected from the group consisting of a vascular cell, a mesenchymal cell, a factor secreted by a vascular cell, a factor secreted by a mesenchymal cell, and a factor secreted when both a vascular cell and a mesenchymal cell exist. A value obtained by assay of a plurality of functions using a Pearson product-moment correlation coefficient is closer to a value of a cell or biological tissue sampled from an adult than a value of a cell or biological tissue sampled from a fetus.
US11060064B2	Early vascular cell population The present invention relates to the area of in vitro cell populations useful for generating vascular networks in vitro and are suitable for use in vivo for regeneration of vascular tissue. In some embodiments, the bipotent cell population of the present invention comprise endothelial cells and pericytes that express vascular endothelial cadherin and are 95% or more positive for CD105 and CD146, and which work syergistically to recreate vascular tissues in vitro.
US11060063B2	Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells Disclosed herein are methods involving the targeting of 5HT biosynthesis in gut insulin-negative cells to convert them into insulin-positive cells. Also, disclosed are methods for treating a disease or disorder in a mammal, preferably a human, associated with impaired pancreatic endocrine function, by administering a therapeutically effective amount of an enumerated active agent that reduces the expression, biosynthesis, signaling or biological activity of serotonin or increases its degradation, wherein administering comprises delivering the agent to Gut Ins− cells in the mammal. Other embodiments of the method are directed to therapy wherein an agent that significantly reduces FOXO1 expression, biosynthesis, signaling or biological activity or increases its degradation is administered in addition to the agent that reduces serotonin, or alternatively an agent that reduces FOXO1 expression is targeted to serotonin-positive gut enteroendocrine cells.
US11060062B2	Generation of glucose-responsive beta cells The present invention relates to a method for generating glucose-responsive beta cells.
US11060061B2	Immortalized sweat gland myoepithelial cell An immortalized sweat gland myoepithelial cell which expresses α-SMA and pan-cytokeratin and has a sphere forming ability after subculture at least 5 times. A method for producing immortalized sweat gland myoepithelial said method comprising: while culturing a cell structure, wherein sweat gland myoepithelial cells are exposed on a surface, in a state of being suspended in a medium, transferring an immortalizing gene into the cells; and then culturing the transgenic structure thus obtained in a state of being suspended in the medium to thereby obtain immortalized sweat gland myoepithelial cells.
US11060059B2	Methods of producing T cell populations enriched for stable regulatory T-cells The present invention provides methods for producing cell populations enriched for stable, regulatory T cells (Tregs). In particular, the invention relates to methods for culturing T cells such that the final culture is enriched for stable, regulatory T cells. It also relates to methods for stabilizing regulatory T cells. Also provided are compositions enriched for stable, regulatory T cells, which are useful for treating individuals in need of such treatment. The methods and compositions disclosed herein can also be used to treat an individual suffering from an immune-mediated disease.
US11060058B2	Perfusion culturing methods and uses thereof Provided herein are methods of culturing a mammalian cell and various methods that utilize these culturing methods. Also provided are multi-well cell culture plates, e.g., for use in perfusion culturing methods.
US11060056B2	Method of producing high amount of ethanol at high temperature by modified yeast strain Saccharomyces cerevisiae The present invention relates to a modified yeast strain of Saccharomyces cerevisiae having MCC accession number 0069 with osmo-tolerant, thermo-tolerant, ethanol tolerant and self-flocculation properties. Further, the present invention relates to a method for obtaining modified yeast strain. The present invention also relates to a method of production of ethanol at high temperature using said yeast strain. The ethanol produced by the method disclosed in the present invention is used as fuel.
US11060052B2	Cleaning composition, method of making and use thereof A method for formulating a cleaning composition contains the step of coating a granular absorbent material with a coating agent to produce a coated absorbent material and mixing the coated absorbent material with a sanitation agent, wherein the coated absorbent material absorbs the sanitation agent to form the cleaning composition. The resulting cleaning composition may be used for cleaning up pathogens or hazardous materials. The cleaning composition may also functions as a liquefiable dry cleaning powder for public areas in response to bodily fluid incidents. A coating method of a non-toxic bio static film on a high surface area solid is disclosed.
US11060051B2	Composition for rinsing or cleaning a surface with ceria particles adhered To provide a composition for rinsing or cleaning a surface to which ceria particles are attached and a surface treatment method for removing ceria particles from the surface using the same.The composition according to the present invention contains an anionic surfactant, an organic amine compound, and a protic organic acid molecule and has a pH of less than 6.
US11060049B2	Use of polypeptide The present invention concerns the use of a polypeptide having deoxyribonuclease (DNase) activity for preventing, reducing or removing static electricity from an item; a composition comprising such polypeptide; a method for reducing or removing static electricity from an item; and a wipe for such use.
US11060047B2	Apparatus and method for extracting essential oils A system and method for extracting essential oils from organic material is provided. One embodiment places organic material into an extraction chamber that is a cylindrical wall of rigid material, wherein a diameter and a height of the extraction chamber is sized to define an interior that accommodates a desired amount of an organic material having essential oils; fills the extraction chamber with a solvent after the organic matter has been placed into the extraction chamber; and moves a vortex plunger disposed over the surface of the organic material in a repeated upward and downward motion during an agitation process so that the vortex vanes generate a fluid vortex in the solvent, wherein the fluid vortex causes the solvent to be drawn upward into the organic material and then to be pushed downward through the organic material so that the solvent extracts essential oils from the organic material.
US11060045B2	Production of renewable waxes and base oils Systems and methods are provided for processing a feed derived from a renewable source to form oligomerized compounds corresponding to waxes, ketone waxes, and/or lubricant boiling range compounds. The oligomerized compounds derived from the renewable source can have various novel properties relative to waxes and/or lubricant boiling range compounds derived from mineral sources or derived from renewable sources in a conventional manner. The oligomerized compounds can be derived from a renewable source including fatty acids and/or fatty acid derivatives, such as glycerides (including triglycerides) and fatty amides. Optionally but preferably, at least a portion of the fatty acids and/or fatty acid derivatives can include olefinic bonds.
US11060039B2	Pyrolysis tar pretreatment This invention relates to thermally-treating and hydroprocessing pyrolysis tar to produce a hydroprocessed pyrolysis tar, but without excessive foulant accumulation during the hydroprocessing. The invention also relates to upgrading the hydroprocessed tar by additional hydroprocessing; to products of such processing; to blends comprising one or more of such products; and to the use of such products and blends, e.g., as lubricants, fuels, and/or constituents thereof.
US11060036B2	Process for the conversion of oxygenates to C5+ hydrocarbons boiling in the gasoline boiling range Process for the conversion of oxygenates to C5+ hydrocarbons boiling in the gasoline boiling range, comprising the steps of continuously a) providing one or more feed streams of one or more oxygenate compounds; b) heating the one or more feed streams to an inlet temperature of one or more downstream conversion reactors; c) introducing the one or more heated feed stream into inlet of the one or more conversion reactors; d) converting in the one or more conversion reactors the one or more heated feed stream in presence of catalyst to a converted oxygenate product comprising C5+ hydrocarbons; e) withdrawing from the one or more conversion reactors the converted oxygenate product; f) determining at outlet of the one or more conversion reactors amount of the one or more unconverted oxygenate compounds in the withdrawn converted oxygenate product; g) separating the converted oxygenate product into a C4− hydrocarbon fraction, a fraction with the C5+ hydrocarbons boiling in the gasoline boiling range and a fraction comprising water and the one or more unconverted oxygenate compounds, wherein the inlet temperature of the one or more feed streams in step b is continuously adjusted to maintain a constant amount of the one or more unconverted oxygenate compounds as determined in step f.
US11060033B2	Compositions and methods for producing calcined coke from biorenewable sources Disclosed are methods of producing calcined coke from bio-oil from a biomass feedstock. Also disclosed are calcined cokes produced by such methods having desirable structural characteristics.
US11060031B2	Fire retardant composition, structure and application Compositions, structures and methods are described that improve fire retardant characteristics of various material, and which can be used for protecting structures, devices, or components therein. In one example, a mixture suitable for imparting heat or cold blocking properties to an object is produced. The mixture includes a catalyst comprising particles that are 8 microns or less in diameter, a charring agent comprising particles that are 8 microns or less in diameter, and a blowing agent comprising particles that are 8 microns or less in diameter. The catalyst, the charring agent and the blowing agent are mixed together in equal portions by weight to produce the mixture suitable for imparting heat or cold blocking properties to an object.
US11060030B2	Negative dielectric anisotropy liquid crystal composition A negative dielectric anisotropy liquid crystal composition having one or more A-R0—B compounds represented by formula I above as a first component, and one or more compounds represented by formula II above as a second component: The liquid crystal composition has a good stability against light and heat, a lower viscosity, a wider refractive index that may be achieved by adjusting the monomer ratio, and a higher clearing point (a very wide service temperature range). The liquid crystal composition has a higher light transmittance, thus allowing a display device to have a higher brightness or an energy saving effect.
US11060029B2	Liquid-crystalline medium and liquid-crystal display comprising the same The invention relates to a liquid-crystalline medium having a nematic phase comprising one or more compounds of formula B wherein the parameters have the meaning given in the text, to the use thereof in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect, to displays of this type which contain a liquid-crystalline medium of this type and to the use of the compounds of formula B for improvement of the transmission and/or response times of a liquid-crystalline medium which comprises one or more additional mesogenic compounds.
US11060027B2	Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same Disclosed are compounds represented by structural formula methods of producing compounds represented by structural formula, and their use in inhibiting oxidation in an oxidizable material.
US11060026B2	Electronic device including quantum dots An electroluminescent device includes a first electrode and a second electrode facing each other, and an emissive layer disposed between the first electrode and the second electrode and including the quantum dots. The quantum dots include a semiconductor nanocrystal core including indium (In) and phosphorous (P), a first semiconductor nanocrystal shell disposed on the semiconductor nanocrystal core, the first semiconductor nanocrystal shell including zinc and selenium, and a second semiconductor nanocrystal shell disposed on the first semiconductor nanocrystal shell, the second semiconductor nanocrystal shell including zinc and sulfur, wherein the quantum dots do not include cadmium. The electroluminescent device has an external quantum efficiency of greater than or equal to about 9% and a maximum brightness of greater than or equal to about 10,000 candelas per square meter (cd/m2).
US11060025B2	Oxynitride fluorescent material, light emitting device, and method for producing oxynitride fluorescent material Provided are an oxynitride fluorescent material, a light emitting device, and a method for producing an oxynitride fluorescent material. The oxynitride fluorescent material containing a composition represented by the following formula (I): (Ba1−aEua)1−bMbSi2O2+cN2+d (I), wherein in the formula (I), M represents at least one element selected from the group consisting of rare earth elements excluding Eu and Sm; and a, b, c, and d each satisfy 0
US11060024B2	Mixed halide scintillators radiation detection Mixed halide scintillation materials of the general formula AB(1−y)MyX′wX″(3−w), where 0≤y≤1, 0.05≤w≤1, A may be an alkali metal, B may be an alkali earth metal, and X′ and X″ may be two different halogen atoms, and of the general formula A(1−y)BMyX′wX″(3−w), where 0≤y≤1, 0.05≤w≤1, A maybe an alkali metal, B may be an alkali earth metal, and X′ and X″ are two different halogen atoms. The scintillation materials of formula (1) include a divalent external activator, M, such as Eu2+ or Yb2+. The scintillation materials of formula (2) include a monovalent external activator, M, such as Tl+, Na+ and In+.
US11060023B2	Coated manganese doped phosphors A process for preparing a population of coated phosphor particles is presented. The process includes combining particles of a phosphor of formula I: Ax [MFy]:Mn4+ with a first solution including a compound of formula II: Ax[MFy] to form a suspension, where A is Li, Na, K, Rb, Cs, or a combination thereof; M is Si, Ge, Sn, Ti, Zr, Al, Ga, In, Sc, Hf, Y, La, Nb, Ta, Bi, Gd, or a combination thereof; x is an absolute value of a charge of the [MFy] ion; and y is 5, 6 or 7. The process further includes combining a second solution including a source A+ ions with the suspension.
US11060022B2	Quantum dot-containing materials and products including same cross reference to related applications A pre-polymer formulation comprising quantum dots and a precursor for a polymer having a free volume parameter VFH2/γ with a value less than or equal to 0.03 cm3/g is disclosed. A pre-polymer formulation comprising quantum dots and a cyclohexylacrylate monomer is further disclosed. Also disclosed are a quantum dot composition including quantum dots dispersed in a polymer matrix, the quantum dot composition being prepared from a pre-polymer formulation comprising quantum dots and a precursor for a polymer having a free volume parameter VFH2/γ with a value less than or equal to cm3/g; a method; and other products including a quantum dot composition described herein.
US11060014B2	Densifying carbon dioxide with a dispersion of carbon dioxide-philic water capsules This invention generally relates to the field of oil recovery from reservoirs. More specifically, it relates to the recovery of oil from sandstone and carbonate reservoirs using a process for preparing a dispersion of capsules for use downhole including the steps of providing capsules containing a dense liquid, each capsule having a capsule wall defining an inner area, the capsule wall having an outer side. The capsules are functionalized by adding a carbon dioxide-philic compound to the outer side of the capsule wall. A dispersion is then prepared by adding the functionalized capsules to supercritical carbon dioxide such that a stable dispersion of capsules in supercritical carbon dioxide is achieved.
US11060011B2	Coil tubing cleanout fluid Coil tubing cleanout fluids comprising a clay are provided. A method may comprise introducing a cleanout fluid into a wellbore wherein the cleanout fluid comprises a carrier fluid and a clay; and entraining solid particles in the cleanout fluid wherein the solid particles are disposed in the wellbore.
US11060009B2	Filtrate reducer for temperature-resistant calcium-resistant water-based drilling fluid used in oil and gas reservoir protection, drilling fluid, and uses thereof A filtrate reducer for temperature-resistant calcium-resistant water-based drilling fluid used in oil and gas reservoir protection, a drilling fluid, and uses of the filtrate reducer and the drilling fluid are described. The filtrate reducer contains structural units represented by formulas (1), (2), and (3) herein. The water-based drilling fluid contains the filtrate reducer, and exhibits good inhibitive, rheological, filtrate reducing, and reservoir protection performance when it is applied in the drilling process in a high-temperature high-calcium deep salt-gypsum formation.
US11060004B2	Adhesives and methods of making the same Embodiments of this invention relate to adhesives, and more particularly to biomimetic heteropolymer adhesive compositions. Certain embodiments relate to biomimetic terpolymer adhesive compositions including dopamine methacrylamide, 3,4-dihydroxyphenylalanine, or 3,4-dihydroxystyrene, mimicking moieties found in marine mussel adhesive proteins. In some embodiments, elastic moduli of the adhesives are preferably selected to match the elastic moduli of the substrates to minimize stress concentrations, to increase the ductility of the adhesive-substrate system, or both.
US11060001B2	Method for producing a moist-crosslinking pressure-sensitive adhesive, moist-crosslinking pressure sensitive adhesive and adhesive tape The present disclosure relates to a method for producing a moist-crosslinking pressure-sensitive adhesive with adjustable adhesive properties, more particularly for producing thick layers of the moist-crosslinking pressure-sensitive adhesive, comprising the following steps: providing, by means of UV-initiated radical polymerisation, a covalently bonded pre-polymer containing alkoxysilyl-terminated monomers to provide a base material suitable for a pressure-sensitive adhesive; adding at least one catalyst to the pre-polymer; and moist-crosslinking this mass to provide a pressure-sensitive adhesive; wherein an aftertreatment of the pressure-sensitive adhesive to adjust application-specific mechanical and/or rheological properties to optimise the adhesive properties such as adhesion, cohesion, visco-elasticity and tack by means of steam and/or temperature. A corresponding moist-crosslinked pressure-sensitive adhesive and an adhesive tape is also described.
US11059999B2	Acrylic rubber foam and double-sided adhesive tape comprising same The present invention relates to a double-sided adhesive tape used for applications including the attachment of front glass for mobile devices. A core layer of the double-sided adhesive tape is prepared by adding an acrylic elastomer free of carbon-carbon double bonds while being highly miscible with an acrylic resin to an acrylic monomer(s) and performing curing, and thus can improve the impact resistance of the final double-sided adhesive tape. Also, the core layer may take a form of foam due to the introduced filler such as glass bubbles or organic microspheres, and thus can further contribute to improving the impact resistance of the final double-sided adhesive tape.
US11059998B2	Waterproof sheet and waterproofing method including using same A waterproof sheet which is for application to a site to be waterproofed in order to prevent rainwater infiltration thereinto and retard deteriorations which proceed with time, the waterproof sheet comprising: a base layer that comprises a silicone rubber composition reinforced with reinforcing fibers and that has physical properties including high strength; and a pressure-sensitive silicone adhesive layer that has been formed on one surface of the base layer and that has a low hardness and is highly tacky. The waterproof sheet provided by the present invention less breaks than conventional waterproof sheets because of the reinforcement layer, and can conform to cracks or dislocations occurring in the surfaces to which the waterproof sheet has been applied, due to the pressure-sensitive adhesive layer formed on one surface. Since the waterproof sheet includes silicones as main components and is hence excellent in terms of weatherability, heat resistance, and freeze resistance, this waterproof sheet can retain the function required of waterproof sheets, over a longer period.
US11059992B2	Waterborne polyurethane coatings The present invention provides waterborne polyurethane coating compositions. When applied to a substrate, the coating compositions of the present invention have good adhesion, transparency, scratch resistance, mar resistance, hardness, solvent resistance, water resistance, and dishwashing resistance. The coating compositions are suitable for application to any suitable substrate, including glass.
US11059991B2	Aircraft fluid resistant sealant for use on aircraft parts A number of sealants are provided that are resistant to degradation by aircraft fluids. In some embodiments, the sealants are resistant to degradation by Jet A fluid and at least one of the three types of hydraulic fluids typically used in aircraft. These embodiments are also typically cure in place from a two part polyurethane or polyurea mix, with cure to a visibly clear coating. In some embodiments, they may be sprayed on an aircraft surface or applied by hand (brush or injectable). In other of these embodiments, the sealants comprise, at least in part, a cured, soft, tacky polyurethane gel that is resistant to at least one of a synthetic hydrocarbon based or mineral oil based hydraulic fluid.
US11059989B2	Crosslinked coating compositions for packaging articles such as food and beverage containers A method of forming a coating on a food or beverage container, which includes spraying a coating composition onto an interior surface of the food or beverage container, where the coating composition includes a latex copolymer and a metal drier or crosslinking agent. The latex copolymer is a reaction product of monomers that include (a) one or more styrene-offset monomers containing one or more cyclic groups and one or more ethylenically-unsaturated pendant groups, at least a portion of such styrene-offset monomers being polycyclic monomers containing ring unsaturation, and (b) one or more other ethylenically-unsaturated monomers. Preferably, the coating composition is substantially free of BPA, PVC, and styrene. The method may also include curing the sprayed coating composition, thereby providing the coating on the interior surface of the food or beverage container.
US11059987B2	Security printing inks for inkjet printers and method of manufacture High security inkjet inks are made my milling two or more functional materials, such as invisible ultraviolet fluorescent dyes or pigments, infrared Anti Stokes upconverting pigments, infrared absorption and fluorescent dyes or pigments and iron oxide magnetic pigments, into a pigment dispersion. A wet media mill is used to mill the pigment dispersion until the average particle size is below 300 nm. The dispersion is combined with main components of an inkjet ink, such as deionized water, humectants, surfactants, polymer resin and biocides, to produce the high security inkjet ink.
US11059986B2	Composition comprising a nanosized light emitting material The present invention relates to a composition comprising a nanosized light emitting material, and method for preparing of said composition. The present invention further relates to a light luminescent medium, a light emitting device, the present invention further more relates to method for preparing of a composition and to method for preparing of a light emitting medium.
US11059985B2	Composition, cured product, storage container, image forming apparatus, and image forming method Provided is a composition including an acrylamide compound (A1) having a molecular weight of 150 or greater but 250 or less, and a trifunctional or higher polymerizable compound (A2), wherein an amount of the trifunctional or higher polymerizable compound (A2) is 1% by mass or greater but 30% by mass or less relative to a total amount of the composition.
US11059984B2	Titanium inks, methods of making and using the same to make titanium articles Ti ink compositions for printing, such as ink jet printing, are disclosed. The ink compositions comprise a liquid dispersion of Ti hydride powder having a mean particle size of less than 10.0 microns; a liquid carrier; and at least one surfactant. Methods of making and using the disclosed inks are also disclosed. For example, a finished Ti product can be produced by printing the disclosed ink composition, such as by ink jet printing, to form a green article, heating the green article to dehydrogenate it and form a Ti containing part. The method may further comprise sintering the Ti containing part to produce a sintered Ti product. In an embodiment, the method comprises printing one or more support materials for the ink composition, that comprises solid particles of a metal oxide, a metal carbide, a metal nitride, a polymer, or combinations thereof.
US11059980B2	Emulsion polymers and stain resistant coating compositions made therefrom Emulsion polymers and coating compositions made therefrom that exhibit exceptional stain resistance to both hydrophilic and hydrophobic stains. The emulsion polymers include, as polymerized units: a) at least one ethylenically unsaturated nonionic monomer in an amount ranging between about 85 wt. % to less than 100 wt. % based on the overall weight of the polymer composition; b) a first acid monomer in an amount ranging from about 0.1 to 2 wt. %, the first monomer being a strong acid monomer selected as a phosphorus-based acid monomer, a sulfur-based acid monomer, or a mixture thereof, and c) a second acid monomer in an amount ranging from about 0.1 to 2 wt. %, the second monomer being one or more ethylenically unsaturated monomers having at least one carboxyl or carboxylic anhydride functional group. The relative amounts of the first and second acid monomers are such that the ratio of b/c is greater than 0.7.
US11059978B2	Chlorinated copper phthalocyanine pigments It is an object of the present technology to overcome the disadvantages of conventional chlorination of a copper phthalocyanine which produces copper phthalocyanine, wherein the number of chlorines is less than than or equal to 4. The pigments described herein contain less chlorine than standard commercial grades of tetrachlorinated (or greater) copper phthalocyanine pigments while achieving similar color space, chromaticity, fastness properties, and color travel in automotive waterborne and solvent borne systems. The inventive pigments are more advantageous from a toxicity and environmental perspective, and allow the manufacturer to produce pigments in a safe and economical manner.
US11059976B2	Asphalt compositions including reclaimed asphalt material Asphalt compositions for use in roofing products are disclosed that include a virgin asphalt material and a reclaimed asphalt material. The asphalt compositions exhibit properties comparable to conventional oxidized asphalt compositions, yet the asphalt compositions are made without using an oxidation or air blowing process.
US11059974B2	Silicon carbonaceous film forming composition comprising polycarbosilane and method for manufacturing silicon carbonaceous film using the same [Problem] To provide a composition comprising polycarbosilane, which has excellent filling property, can form a film at a lower temperature, and makes electrical property of the produced film excellent. [Means for Solution] A silicon carbonaceous film forming composition comprising polycarbosilane and a solvent, wherein the ratio of the integrated intensity at 3.92 to 4.20 ppm to the integrated intensity at 3.60 to 5.50 ppm in the H-NMR spectrum of said polycarbosilane is 27 to 50%.
US11059973B2	Heat-curable resin composition and semiconductor device Provided are a resin composition capable of yielding a cured product exhibiting a superior heat resistance over a long period of time, and a superior reflow resistance due to a low water absorption rate even at a high temperature; and a semiconductor device encapsulated by such cured product. The resin composition is a heat-curable resin composition containing: (A) an organopolysiloxane having, in one molecule, at least one cyclic imide group and at least one siloxane bond; (B) an inorganic filler; and (C) a radical polymerization initiator. The semiconductor device is encapsulated by the cured product of such heat-curable resin composition.
US11059970B2	Cross-linkable coating compositions based on organyl oxysilane-terminated polymers Crosslinkable compositions especially useful for coatings containing an alkoxysilyoxy-terminated polymer and a silicone resin.
US11059967B2	Epoxy stabilization using acid-coated nitrogen containing catalysts, particles, and methods A catalyst-containing particle including a core and an acidic coating layer thereon, wherein the core includes a nitrogen-containing catalyst for a thermoset polymeric system, and the acidic coating layer comprises a binder; and a method of making such particles. A curable, one-part epoxy/thiol resin composition that includes: an epoxy/thiol resin mixture including: an epoxy resin component that includes an epoxy resin having at least two epoxide groups per molecule; a thiol component that includes a polythiol compound having at least two primary thiol groups; and catalyst-containing particles dispersed in the epoxy/thiol resin mixture; wherein each particle includes a core and an acidic coating layer thereon, wherein the core includes a nitrogen-containing catalyst for the epoxy resin; and a method of curing such curable composition.
US11059966B2	Liquid epoxy resin composition for sealing, and electronic component device A liquid epoxy resin composition for sealing includes an epoxy resin, a curing agent, and a particle having a core-shell structure. In the composition, the particle having a core-shell structure includes a core including a cross-linked polysiloxane and a shell including a polymer in which the content of a structural unit having an epoxy group is 10% by mass or more.
US11059959B2	Tire including RFID system A tire includes a radio frequency identification (RFID) system and a rubber patch including a topping rubber topping the RFID system, wherein the topping rubber includes a raw material rubber and a reinforcing filler including a boron nitride. In the tire including a RFID system, since the RFID system is covered with a rubber similar to a nearby rubber, generation of a boundary therebetween is suppressed to lower a possibility of the occurrence of initial cracking at a portion where the RFID system is applied, thus increasing durability and safety, and since insulating properties of the rubber covering the RFID system are enhanced, a recognition distance of the RFID system is increased to further facilitate management of distribution and history.
US11059948B2	Shape memory-based self-healing polymer composite reinforced with graphene foam A shape-memory epoxy polymer graphene foam composite (SMEP-GrF) is formed from an open cell graphene foam (GrF) surrounded by and infiltrated with a shape-memory epoxy polymer (SMEP) matrix, with the GrF being an intra-connected framework within the SMEP matrix. The SMEP-GrF provides self-healing properties to a device fabricated from the SMEP-GrF. The SMEP-GrF is formed by infusion of an epoxy resin and hardener in an open cell GrF and curing the infused GrF.
US11059942B2	Aromatic polyesters from biosuccinic acid Biosuccinic acid, obtained via sugar fermentation, is cyclodimerized and oxidized to yield building blocks for aromatic polyesters with high glass transition temperatures.
US11059941B2	Methods for preparing materials from polyaromatic heavy feedstocks The present disclosure relates to methods for preparing materials from heavy feedstocks. In particular, the disclosure provides a chemical process to convert heavy feedstocks with predominant polyaromatic hydrocarbon molecules or species, including the residues of petrochemical refining or extraction, into thermoset or thermoplastic materials that can be used alone or as a component in a composite material.
US11059939B2	Dicyclopentadiene derivatives and polymers thereof Dicyclopentadiene (DCPD) derivatives of following general formula (I); their preparation and use thereof, especially as monomers in polymerization reactions, such as olefin polymerization or ring-opening metathesis polymerization (ROMP).
US11059938B2	Film composition and a film prepared thereby The disclosure provides a film composition, wherein the film composition includes an oligomer and a crosslinking agent. The oligomer can have a structure represented by Formula (I) wherein R1 and R2 are independently hydrogen, C1-20 alkyl group, C2-20 alkenyl group, C6-12 aryl group, C6-12 alkylaryl group, C5-12 cycloalkyl group, C6-20 cycloalkylalkyl group, alkoxycarbonyl group, or alkylcarbonyloxy group; R1 is not hydrogen when R2 is hydrogen; a is 0 or 1; 100≥n≥1; 100≥m≥1; and when n is not 0, the ratio of n to m is from 3:1 to 1:4. The weight ratio of the oligomer and the crosslinking agent can be from 9:1 to 3:7. The oligomer has a number average molecular weight (Mn) from 1,000 to 8,000.
US11059932B2	Catalyst composition for producing polyurethane foam, and method for producing flexible polyurethane foam using it To provide a catalyst composition to obtain a flexible polyurethane foam from which substantially no amine compound is discharged and which has sufficient resistance to compressive strain, and a method for producing a flexible polyurethane foam using the catalyst composition.A polyurethane foam is produced by using a catalyst composition for producing a polyurethane foam, which comprises an amine compound represented by the following formula (1) and at least one glycol selected from the group consisting of ethylene glycol and polyethylene glycol, provided that when the compound of the formula (1) has enantiomers, diastereomers or geometric isomers, both a mixture thereof and isolated isomers are included: wherein R1, R2, R3 and R4 are each independently a hydrogen atom, a C1-4 alkyl group, a hydroxy group, a hydroxymethyl group or a C1-4 alkoxy group, and m is an integer of 1 or 2.
US11059925B2	Method and system for producing a polymer The invention relates to a method for producing a polymer from a first component and a second component by means of a reactor (50), wherein reaction heat in the reactor (50) is discharged via an evaporative cooler (40), wherein gaseous exhaust vapour in the reactor (50) is supplied to the evaporative cooler (40), and condensed exhaust vapour is guided from the evaporative cooler (40) back into the reactor (50). In this way, the first component and/or second component are supplied at least partially via the evaporative cooler (40) and moved from the evaporative cooler (40) into the reactor (50). The invention also relates to a system for producing a polymer, comprising a reactor (50) and an evaporative cooler (40) for discharging reaction heat in the reactor (50). In addition, the evaporative cooler (40) has at least one filling opening (46) for filling in the first and/or second component.
US11059923B2	Preparation method for high-solid acrylic resin Disclosed is a preparation method for a high-solid acrylic resin, comprising the following steps: preparing acrylic acid or methacrylic acid, an alkyl acrylate or alkyl methacrylate, styrene, hydroxyethyl acrylate or hydroxypropyl acrylate, an acrylate with a bridge ring structure, an initiator, and a solvent; adding the solvent to a reactor, stirring, and increasing the temperature to the boiling point temperature of the solvent; adding the reaction raw materials and the initiator from a dropping funnel and stirring, and after the completion of the addition, maintaining the boiling point temperature of the solvent and continuously stirring; and cooling and discharging after the reaction is finished. The Gardner-Holdt tube viscosity of the prepared acrylic resin is 15-25 S (25° C.), and the solid content is 70%-75%.
US11059922B2	Method for cross-linking polymers The invention relates to a method for manufacturing a cross-linked polymer comprising reacting at least one polymer having at least one —SO2X group, with X being F or Cl, a basic compound, and certain salts including a ring-quaternized pyridinium-type nitrogen, and possessing at least two groups in ortho or para position thereto comprising reactive hydrogen atoms; cross-linking has been proven to proceed effectively, delivering cross-linked polymers possessing improved chemical resistance and mechanical performances.
US11059918B2	Metallocene catalyst compositions and polymerization process therewith This invention relates bisindenyl metallocene catalyst compounds having long (at least 4 carbon atoms) linear alkyl groups substituted at the two position and substituted or unsubstituted aryl groups at the four position and process using such catalyst compounds, particularly in the solution process at higher temperatures.
US11059917B2	Ligand compound, transition metal compound, and catalyst composition including the same The present invention relates to a novel ligand compound, a transition metal compound and a catalyst composition including the same. The novel ligand compound and the transition metal compound of the present invention may be useful as a catalyst of polymerization reaction for preparing an olefin-based polymer having a low density. In addition, an olefin polymer which is polymerized using the catalyst composition including the transition metal compound may be used for the manufacture of a product having low melt index (MI) and high molecular weight.
US11059914B2	Method for the continuous synthesis of a diene elastomer with lithium amide initiator A process for the continuous synthesis of a diene elastomer is provided. The synthesis is conducted by means of n reactors r1 to rn, considered to be continuous stirred-tank reactors, which are equipped with an internal stirring system. The reactors are arranged in series, n varying from 2 to 15, preferably from 2 to 9. The reactor r1 is fed by an input solution comprising a solvent, one or more monomer(s), an anionic polymerization initiator chosen from lithium amides and a polar agent. The conversion by weight C1 in the first reactor is less than 70%, and the total conversion by weight Cn at the outlet of the reactor rn is greater than or equal to 70%.
US11059913B2	Polymerization and isolation of low viscosity polymers using pastillation technology A process to form an olefin-based polymer, said process comprising at least the following steps: a) polymerizing a reaction mixture comprising an olefin, in at least one reactor, in a solution polymerization, to form a polymer solution; b) feeding at least a portion of the polymer solution through at least one devolatilizer, to form the olefin-based polymer, in melt form; c) feeding at least a portion of the olefin-based polymer, in melt, form through a heat exchanger, and then into a pastillation apparatus to form polymer particles.
US11059909B2	Engineered IgA antibodies and methods of use Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
US11059906B2	Anti-CCL2 and anti-LOXL2 combination therapy for treatment of scleroderma The present invention provides, among other things, bi-specific molecules including, but not limited to, antibodies, fynomers, aptamers, fusion proteins, and protein binding domains that bind both CCL2 and LOXL2 and uses thereof, in particular, for treatment of scleroderma and related fibrotic and/or inflammatory diseases, disorders and conditions. In some embodiments, the present invention further provides methods and compositions for treatment of scleroderma and related fibrotic and/or inflammatory diseases, disorders and conditions based on the combination of mono-specific anti-CCL2 and anti-LOXL2 molecules.
US11059903B2	Anti-PSMA antibodies, uses thereof and conjugates thereof An antibody or antigen-binding portion thereof which binds to PSMA and comprises a heavy chain variable domain comprising the sequences: CDR1: EYTIH (SEQ ID NO: 33) CDR2: NINPNX1GGTTYNQKFED (SEQ ID NO: 34) CDR3: X2-5DY (SEQ ID NO: 35) wherein X1 is N or Q, and X2-5 is YWLF (SEQ ID NO: 39), GWTF (SEQ ID NO: 40) or AWTM (SEQ ID NO: 41), and wherein if X2-5 is GWTF (SEQ ID NO: 40) or AWTM (SEQ ID NO: 41), the amino acid residue at position H94 in the heavy chain variable region, based on Kabat numbering, is G; and if X2-5 is YWLF (SEQ ID NO: 39), the amino acid residue at position H94 in the heavy chain variable region, based on Kabat numbering, is A. The invention also provides compounds that include the antibody or antigen-binding portion thereof, such as conjugates, and their use in the treatment or diagnosis of disease, in particular cancers, particularly prostate cancer.
US11059901B2	Compositions and methods related to xCT antibodies Certain embodiments are directed to therapeutic compositions having an xCT specific antibody.
US11059899B1	Polypeptides that bind glucocorticoid-induced TNFR family-related receptor (GITR) The present invention relates to immunoglobulin single variable domains that bind GITR and more in particular to polypeptides that comprise or essentially consist of one or more such immunoglobulin single variable domains; to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the polypeptides of the present invention enhance the biological activity of GITR.
US11059896B2	Stabilized formulations containing anti-interleukin-4 receptor (IL-4R) antibodies The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
US11059893B2	Humanized anti-AXL antibodies The present disclosure relates to humanized anti-Axl antibodies.
US11059892B2	Engineered antibody Fc variants for enhanced serum half life In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.
US11059891B2	Chimeric antigen receptors targeting Fc receptor-like 5 and uses thereof The presently disclosed subject matter provides for methods and compositions for treating a neoplasia (e.g., multiple myeloma). It relates to chimeric antigen receptors (CARs) that specifically target Fc Receptor-like 5 (FcRL5), e.g., domain 9 of FcRL5, and immunoresponsive cells comprising such CARs. The presently disclosed FcRL5-targeted CARs have enhanced immune-activating properties, including anti-tumor activity.
US11059887B2	Anti-claudin 18.2 antibodies and uses thereof Provided are antibodies or fragment thereof having binding specificity to the wild-type human claudin 18.2 (CLDN18.2) protein and also capable of binding the M149L mutant. By contrast, such antibodies and fragments do not or weakly bind to claudin 18.1 (CLDN18.1).
US11059884B2	Antibodies directed against Staphylococcus aureus leukotoxins The present disclosure is directed to leukotoxin-binding antibodies and antigen-binding fragments thereof. The antibodies and fragments can be used, for example, to detect leukotoxin and/or in methods of treating and preventing Staphylococcus aureus infections.
US11059883B2	Antibody molecules to dengue virus and uses thereof Antibody molecules that specifically bind to dengue virus are disclosed. In certain embodiments, the antibody molecule bind to dengue virus serotypes DV-1, DV-2, DV-3, and DV-4. The antibody molecules can be used to treat, prevent, and/or diagnose dengue virus.
US11059882B2	Anti-HIV dual specificity antibodies and methods of HIV treatment Dual variable domain immunoglobulins (DVD Igs) are provided capable of tetravalent binding to bispecific sites of the human immunodeficiency virus (HIV). The DVD Igs may be asymmetric and may have more variable domains on either the light chain or the heavy chain of the Igs. The DVD Igs may have specificity for gp41 and gp120. Therapies are provided using DVD Igs to neutralize HIV viral loads.
US11059881B2	Method for measuring viscosity of protein solution The inventors discovered that viscosity of a protein solution can be estimated by measuring the apparent particle size or apparent molecular weight by a small angle X-ray scattering (SAXS) method or X-ray solution scattering method, which enables measurement of small amounts of samples, and then correlating those measurement results with viscosity of the protein solution.
US11059876B2	IL-15 variants and uses thereof The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.
US11059872B2	Self-assembly of protein-based biomaterials with multiple morphologies The present disclosure relates, in some embodiments, to a composition comprising a biomaterial. A biomaterial may comprise, for example, one or more molecules capable of self-association and/or self-assembly. In some embodiments, a biomaterial may comprise one or more polypeptides and/or proteins. A biomaterial may comprise, for example, two or more self-assembled Ultrabithorax (Ubx) protein molecules. A Ubx protein, in some embodiments, may be any wild type Drosophila melanogaster Ultrabithorax protein, including any natural or non-natural isoforms (e.g., alternative splicing isoforms). The present disclosure relates, in some embodiments, to a method of making a biomaterial comprising contacting two or more Ubx protein molecules under conditions that permit self-assembly to form a first fibril and contacting the first fibril to a second fibril.
US11059871B2	SYNP162, a promoter for the specific expression of genes in rod photoreceptors The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 300 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
US11059864B2	Chimeric antigen receptor (CAR) modulation The technology described herein is directed to CAR polypeptides and systems comprising repressible proteases. In combination with a specific protease inhibitor, the activity of said CAR polypeptides and systems and cells comprising them can be modulated. Also described herein are methods of using said CAR polypeptides and systems, for example to treat various diseases and disorders.
US11059863B2	Stabilized human immunodeficiency virus (HIV) envelope (ENV) trimer vaccines and methods of using same The invention features stabilized human immunodeficiency virus (HIV) envelope (Env) trimers. The invention also features vaccines, nucleic acids, and vectors to deliver and/or facilitate production of the stabilized HIV Env trimers. In addition, the invention features methods of making and using the stabilized HIV Env trimers of the invention.
US11059857B2	Chromatographic method for collecting blood coagulation factor VII with high yield A chromatographic method for collecting blood coagulation factor VII (Factor VII) and/or activated blood coagulation factor VII (activated Factor VII) from plasma-derived fractions with high yield is provided. In accordance with the method of the present invention, Factor VII and/or activated Factor VII of interest can be collected with a recovery rate of as high as 90% or more by letting Factor VII and/or activated Factor VII which fails to be adsorbed to a first anion exchange resin and remains in a non-adsorption fraction be adsorbed in a second anion exchange resin.
US11059856B2	Use of a polymeric mesh for the purification of macromolecules Method for recovering a target protein from a feedstock comprising said target protein and at least one impurity compound selected from host cell proteins (HCP), DNA, RNA or other nucleic acid, the target protein being characterized by a hydrodynamic radius Rh1 and the impurity compound being characterized by a hydrodynamic radius Rh2, wherein Rh1>Rh2, comprising the following steps (i) to (iv) and optionally step (v): (i) providing a polymeric mesh comprising at least one crosslinked polymer containing positively charged amino groups, wherein the polymer has a pore size exclusion limit Rhi which can be set variably; (ii) adapting the variable pore size exclusion limit Rhi of the polymeric mesh such that Rh2Rhi; (iii) contacting the polymeric mesh with the feedstock; (iv) separating the polymeric mesh containing the retained impurity compound from the feedstock containing the excluded target protein.
US11059853B2	Crystalline or amorphous form of steroid derivative FXR agonist, preparation method therefor and use thereof Disclosed are a crystalline or amorphous form of steroid derivative FXR agonist (formula I), and a preparation method therefor, and a crystalline composition and pharmaceutical composition comprising the crystalline or amorphous form, and the use of same in the preparation of a drug for treating or preventing various conditions associated with FXR.
US11059852B2	Ergostenol glycoside derivative The present invention provides ergostenol glycoside derivatives, method for preventing, treating, or alleviating dermatitis using the same. The present invention also provides a method for preparing the ergostenol and glycoside derivatives thereof. The ergostenol and the glycoside derivatives thereof according to the present invention suppress the production of chemokines increasing according to the skin inflammation stimulation and inhibit the activity of transcriptional factors controlling the expression of various inflammation mediators in the prevention and treatment of dermatitis.
US11059851B2	Process for the purification of methylcobalamin The present invention relates to a process for the purification of methylcobalamin, namely from iron cyanide impurities, comprising contacting a solution comprising methylcobalamin and iron cyanide anions with a strongly basic anion exchange resin. This purification process can advantageously be used for removing iron cyanide impurities from methylcobalamin obtained by reductive methylation of cyanocobalamin and wherein iron (II) salts are used as cyanide scavengers, thus providing methylcobalamin with a reduced iron content. Methylcobalamin (R is methyl).
US11059848B2	Artemisinic acid glycoconjugate compounds, process for preparation and use thereof The present invention relates to artemisinic acid glycoconjugate compounds. More particularly, the present invention relates to a glycoconjugate compound of formula (I) and a process for the preparation of artemisinic acid glycoconjugate compound of formula (I) by using 1,3-dipolar cycloaddition chemistry starting from artemisinic acid.
US11059847B2	Crystal forms of β-nicotinamide mononucleotide The invention relates to crystalline forms of a β-nicotinamide mononucleotide, methods of their preparation, and related pharmaceutical preparations thereof. The invention also relates to preparations suitable for nutraceutical, veterinary, and agriculturally-relevant uses.
US11059846B2	Immune stimulating compound The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating intracellular bacterial, fungal, and protozoal infections.
US11059834B2	Macrocyclic immunomodulators Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
US11059825B2	CXCR7 antagonists Compounds having formula I, or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present invention provides in further aspects, compositions containing one or more of the above-noted compounds in admixture with a pharmaceutically acceptable excipient.
US11059822B2	MAGL inhibitors Provided herein are spirocyclic and fused bicyclic carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
US11059820B2	Crystalline forms of seletalisib Crystalline forms of seletalisib, designated as Form B and Form F and characterized herein, being selective inhibitors of PI3 kinase enzymes, in particular of the human PBKδ isoform, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
US11059818B2	Triazolopyridine inhibitors of myeloperoxidase The present invention provides compounds of Formula (I). wherein A and Z are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and may be useful for the treatment and/or prophylaxis of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
US11059810B2	Pharmaceutically acceptable salt as renal outer medullary potassium channel inhibitor A pharmaceutically acceptable salt as a renal outer medullary potassium channel (ROMK) inhibitor, specifically an L-tartrate and a crystal form I and crystal form II thereof, is described. The pharmaceutically acceptable salt of the ROMK inhibitor, specifically the L-tartrate, has improved bioavailability and stability.
US11059809B2	Substituted cyanopyrrolidines with activity as DUB inhibitors The present invention relates to a class of substituted-cyanopyrrolidines of formula (Ia), (Ib), and (Ic), with activity as inhibitors of deubiquitilating enzymes, in particular, ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30), having utility in a variety of therapeutic areas including cancer and conditions involving mitochondrial dysfunction (Ia).
US11059806B2	Pyrazole derivatives The present invention relates to pyrazole derivatives of formula (X) wherein ring A is a pyrazole and substituents RB1, RB2, n, RQ1, RQ2, RQ3, and RQ4 are as defined in claim 1, their manufacture, and their use in the manufacture of agrochemicals and pharmaceuticals.
US11059797B2	Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide The present invention relates to: a process for preparing 3,7-bis-(dimethylamino)-phenothiazin-5-ium bromide or chloride; a method of converting 3,7-bis-(dimethylamino)-phenothiazin-5-ium bromide to 3,7-bis-(di-methylamino)-phenothiazin-5-ium chloride; and the purification of 7-bis-(di-methylamino)-phenothiazin-5-ium chloride by crystallization from aqueous solution of hydrochloric acid, leading to a pharmaceutically acceptable 3,7-bis-(di-methylamino)-phenothiazin-5-ium chloride (methylthioninium chloride, methylene blue, MTC) of formula I below reported.
US11059793B2	Process for melamine purification A process for the purification of a melamine melt (5) containing melamine and by-products, comprising the steps of: (a1) quenching of said melamine melt; (a2) decomposition of by-products with alkali, providing an alkaline aqueous solution of melamine (26); (b) stripping of said alkaline aqueous solution of melamine (26); (c) crystallization of melamine with a first alkali-containing solution (6b) and separation of solid melamine (7) from a mother liquor (8); (d) treatment of said mother liquor, providing a waste water stream (11) containing carbonates; (e) decomposition of at least part of the carbonates contained in said waste water stream (11) into carbon dioxide and alkali, providing a second alkali-containing aqueous solution (30); (f) recycle of at least part of said alkali-containing aqueous solution (30) to at least one of said steps (a1), (a2) and (c).
US11059791B2	Non-coordinating anion type benzimidazolium activators The present disclosure provides benzimidazolium borate activators comprising benzimidazolium cations having linear alkyl groups, catalyst systems comprising, and processes for polymerizing olefins using such activators. Specifically, the present disclosure provides polymerization activator compounds which may be prepared in, and which are soluble in aliphatic hydrocarbon and alicyclic hydrocarbon solvents.
US11059787B2	Crystalline form of lenvatinib mesylate and methods thereof The present invention provides a novel crystalline form of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide methanesulfonate (i.e., lenvatinib mesylate) and pharmaceutical compositions thereof. Methods of preparing such a crystalline form and uses in treatment are also provided.
US11059784B2	Oxime ether compounds Disclosed are compounds of Formula (I): (I) or a salt thereof, wherein: X is CH or N; Y is CH or N; R1 is —OH or —OP(O)(OH)2; L is —CR3═N—O—CRaRa— or CRaR—O—N═CR3; L2 is a bond, —C(O)—, or S(O)2—; and R2, R3, Ra, m, and n are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
US11059783B2	Pyridinyl cyclohexanecarboxamide cooling compounds A method of providing a cooling effect to a product includes the incorporation into the product of at least one compound of the formula I in which m is a number between 0 and 2, X, Y and Z are selected independently from the group consisting of H, halogen, OH, Me, Et, MeO and EtO, and R1, R2 and R3 together comprise at least 6 carbons, selected such that (a) (i) R1 is selected from the group consisting of H, Me, Et, isopropyl and C4-C5 branched alkyl; and (ii) R2 and R3 are independently selected from the group consisting of Me, Et, isopropyl and C4-branched alkyl; or (b) any two or all of R1, R2 and R3 together form a monocyclic, bicyclic or tricyclic radical having up to 10 carbons. The compounds confer substantial cooling effects on compositions applied to the skin or taken orally, such as toothpastes, mouthwashes, foodstuffs, beverages, confectionery, tobacco products, skin creams and ointments.
US11059782B2	Method for aromatic fluorination Disclosed is a fluorination method comprising providing a fluorinating reagent and a solvent to a reaction mixture; providing a compound having the formula Ar—X to the reaction mixture; wherein Ar is aryl, substituted aryl, heteroaryl or substituted heteroaryl, and X is Cl, Br, I or NO2, providing tetramethylammonium 2,6-dimethylphenolate to the reaction mixture; and reacting under conditions sufficient to provide a species having the formula Ar—F.
US11059776B2	Method of enhanced conversion of taurine salts to alkyl taurate amides The invention relates to a method of enhancing conversion of alkali metal salt, preferably aqueous salt, preferably aqueous sodium salt of N-methyl taurine to alkyl taurate amides. In one aspect, the starting salt is pre-concentrated (at least 75% up to 99% taurine salt in the aqueous solutions after water is removed from a starting aqueous solution of the salt) and, in another aspect, the starting salt is not pre-concentrated.
US11059770B2	Process for purification of vinyl acetate for use in polymerization in the presence of ethylene Process for purification of unreacted vinyl acetate monomers comprising the steps of preliminarily loading an adsorbent agent bed with a mixture comprising an inert gas and fresh vinyl acetate; and feeding said adsorbent agent bed with unreacted vinyl acetate monomers to remove acetic acid.
US11059769B2	Production and separation of 3-hydroxypropionic acid The disclosure provides methods and apparatus for producing 3-hydroxypropionic acid or a salt thereof, for removing 3-hydroxypropionic acid from aqueous solution (e.g., aqueous broth), and for using it to make various chemicals.
US11059767B2	Process for the production of 2,3,3,3-tetrafluoropropene The present invention relates to a process for the gas-phase production of 2,3,3,3-tetrafluoropropene, comprising the steps: i) providing a composition A comprising 2-chloro-3,3,3-trifluoropropene and/or 2,3-dichloro-1,1,1-trifluoropropane and/or 2-chloro-1,1,1,2-tetrafluoropropane or a composition B comprising 1,1,1,2,2-pentafluoropropane and/or 1,1,1,2,3-pentafluoropropane; ii) placing said composition A in contact with hydrofluoric acid in the presence of a catalytic composition comprising a chromium-based catalyst or placing said composition B in contact with a catalytic composition comprising a chromium-based catalyst to produce a composition C comprising 2,3,3,3-tetrafluoropropene, characterized in that step ii) is performed at a temperature of between 310° C. and 450° C. and in that the temperature of step ii) is controlled so as not to exceed 450° C.; and when said catalyst is deactivated, the temperature of step ii) is increased in increments from 0.5° C. to 20° C. on condition that the temperature does not exceed 450° C.
US11059765B2	Method of retrofitting a system for recovering paraxylene A method for retrofitting a system for recovering paraxylene. The system is retrofitted with a pressure swing adsorption unit and a second isomerization reactor. The retrofit lowers the variable cost of the plant, while providing the opportunity to maintain existing equipment and furnace and refrigeration duty.
US11059762B2	Selective hydrogenation methods The present disclosure relates to methods for selectively hydrogenating acetylene, to methods for starting up a selective hydrogenation reactor, and to hydrogenation catalysts useful in such methods. In one aspect, the disclosure provides a variety of methods for starting up reactors for use in methods for selectively hydrogenating acetylene using a catalyst composition comprises a porous support, palladium, and one or more ionic liquids.
US11059761B2	Aerobic hose wrap composting apparatus and method for decomposing waste material Decomposing waste material may use a no-turn, aerobic composting apparatus that includes an enclosure for containing waste material and a fluid distribution system including a fluid injection member removably disposable in waste material disposed in the enclosure. The fluid injection member includes a plurality of spaced apertures for injecting fluid into the waste material.
US11059759B2	Methods and compositions for increasing the amounts of phosphorus available for plant uptake from soils The present invention relates to a method of enhancing growth conditions for plants by growing the plants in soil containing, in proximity to the plant roots, both a phosphorus source and at least two strains of the fungus Penicillium, particularly P. bilaiae, more particularly strains NRRL 50162 and NRRL 50169.
US11059751B2	Coated member, coating material, and method of manufacturing coated member A coated member includes a heat-shielding coating layer made of a zirconia-dispersed silicate in which ytterbia-stabilized zirconia is precipitated as a dispersed phase in a matrix phase which is any one of a rare earth disilicate, a rare earth monosilicate, and a mixed phase of the rare earth disilicate and the rare earth monosilicate. The rare earth disilicate is a (Y1-a[Ln1]a)2Si2O7 solid solution wherein Ln1 is any one of Sc, Yb, and Lu, or a (Y1-c[Ln2]c)2Si2O7 solid solution wherein Ln2 is any one of Nd, Sm, Eu, and Gd. The rare earth monosilicate is Y2SiO5, [Ln1′]2SiO5, a (Y1-b[Ln1′]b)2SiO5 solid solution wherein Ln1′ is any one of Sc, Yb, and Lu, or a (Y1-d[Ln2′]d)2SiO5 solid solution wherein Ln2′ is any one of Nd, Sm, Eu, and Gd.
US11059746B2	Thermoplastic cycloaliphatic polyamide matrix resins for next-generation energy absorbing applications Provided are materials that include one or more cycloaliphatic polyamides integrated into or coated onto one or more structural fibers such as polyethylene fibers, aramid-fibers, glass fibers or carbon fibers. The resulting materials may be incorporated into composite articles suitable for use as protective equipment or structural layers.
US11059743B2	Substrate provided with coating film Disclosed is a process for producing a film-coated substrate having a relatively flat distribution of film thickness such that the film thickness is suppressed from gradually increasing toward a downstream side of flow of a coating liquid even when a coating film is formed on a plate-shaped substrate by a flow coating method in which the substrate is held in raised attitude. The film-coated substrate according to the present invention is employed in particular as an openable/closable window glass of an automotive door, and is suitable for one where the substrate includes an uncoated region where no coating film is formed, wherein the uncoated region is configured to be received in a receiving part of an upper frame of the door.
US11059742B2	Thermally stable, flexible substrates for electronic devices A flexible substrate with a high optical transparency (>80% from 400 to 750 nm) that is retained after exposure to 300° C., near-zero birefringence (<±0.001), and a relatively low CTE (<60 ppm/° C.) is disclosed. The substrate may be manufactured as single layer, polyimide films and as a multi-layer laminate comprising a polyimide layer and a thin glass layer. The polyimides may include alicyclic dianhydrides and aromatic, cardo diamines. The films formed of the polyimides can serve as flexible substrates for optical displays and other applications that require their unique combination of properties.
US11059740B2	Glass article containing a coating with an interpenetrating polymer network A glass article comprising a glass substrate and a coating on a surface of the glass substrate is disclosed. The coating comprises a glass frit and a binder comprising an interpenetrating polymer network. The interpenetrating polymer network comprises a crosslinked polyol resin, a second crosslinked resin, and a third resin. A method of forming the glass article containing the coating is also disclosed.
US11059738B2	Low CTE boro-aluminosilicate glass for glass carrier wafers A low CTE boro-aluminosilicate glass having a low brittleness for use in wafer-level-packaging (WLP) applications is disclosed. The glass comprises a composition in mol-% of SiO2: 60-85, Al2O3: 1-17, B2O3: 8-20, Na2O: 0-5, K2O: 0-5, MgO: 0-10, CaO: 0-10, SrO: 0-10, and BaO: 0-10. An average number of non-bridging oxygen per polyhedron (NBO) is equal to or larger than −0.2 and a ratio B2O3/Al2O3 is equal to or larger than 0.5. The NBO is defined as NBO=2×Omol/(Simol+Almol+Bmol)−4. A glass carrier wafer made from the low CTE boro-aluminosilicate glass and a use thereof as a glass carrier wafer for the processing of a silicon substrate are also disclosed, as well as a method for providing a low CTE boro-aluminosilicate glass.
US11059737B2	Method for manufacturing multicore optical fiber A method for manufacturing a multicore optical fiber includes a step of forming ring-shaped closed-end holes to axially extend from a first end toward a second end of a glass rod; a step of heating bottom parts of the ring-shaped closed-end holes and softening center rods surrounded by the ring-shaped closed-end holes; a step of pulling out the center rods toward a side of the first end, forming columnar closed-end holes from the ring-shaped closed-end holes, and treating the glass rod as a cladding material; a connecting step of connecting a supporting pipe to the first end; an inserting step of inserting core rods into the columnar closed-end holes after the connecting step; and a drawing step of drawing the cladding material and the core rods while heating a portion near the second end and integrating the cladding material and the core rods after the inserting step.
US11059732B2	Reconfigurable leaching module Reconfigurable water leaching modules are provided herein. These modules may comprise a plurality of dosing conduits and a plurality of leaching channels fluidly coupled to the dosing conduits where the leaching channels are reconfigurable from a first retracted position to a second extended position and where the leaching channels may hang downwardly from the dosing conduits in the second extended position.
US11059730B2	Electromagnetic fluid separation and combination Electromagnetic processing of fluid materials is disclosed. Separation of one or more ionic components of a fluid, and combination of one or more ionic components in a fluid, are discussed.
US11059726B2	Fluorescent material and method for making the same A fluorescent material includes at least one fluorescent compound having a structure formula of ABXZY3-Z as defined in the specification, a plurality of NH3+ group-containing ions bound to the fluorescent compound through protonation of amine groups of an amine composition, and a plurality of COO− group-containing ions bound to the fluorescent compound through deprotonation of carboxyl groups of an acid composition. The amine composition has a total hydrogen bonding Hansen solubility parameter (TδH) ranges from 2.4 to 3.3 (cal/cm3)1/2, and the acid composition has a total polar Hansen solubility parameter (TδP) which is less than 1.4 (cal/cm3)1/2.
US11059725B2	Rare earth cold accumulating material particles, and refrigerator, superconducting magnet, inspection device and cryopump using same The present invention provides a rare earth cold accumulating material particle comprising a rare earth oxide or a rare earth oxysulfide, wherein the rare earth cold accumulating material particle is composed of a sintered body; an average crystal grain size of the sintered body is 0.5 to 5 μm; a porosity of the sintered body is 10 to 50 vol. %; and an average pore size of the sintered body is 0.3 to 3 μm. Further, it is preferable that the porosity of the rare earth cold accumulating material particle is 20 to 45 vol. %, and a maximum pore size of the rare earth cold accumulating material particle is 4 m or less. Due to this structure, there can be provided a rare earth cold accumulating material having a high refrigerating capacity and a high strength.
US11059721B2	Production of synthesis gas from natural gas with copper—iron—manganese oxide oxygen carriers/catalysts via partial oxidation and dry reforming processes Materials, methods of making, and methods of providing a trimetallic oxygen carrier for converting methane containing fuel to synthesis gas. The trimetallic oxygen carrier comprises CuxFeyMnzOt, where CuxFeyMnzOt is a chemical composition with 00, s>0 and u>0 and combinations thereof. Reaction of trimetallic CuxFeyMnzOt with methane generates a product stream comprising at least 50 vol. % CO and H2.
US11059719B2	Process for producing hydrogen or syngas by methanol cracking In a process for producing hydrogen or syngas by methanol cracking, whereby methanol is catalytically decomposed into hydrogen and carbon monoxide in an endothermal reaction, said reaction takes place in a reactor with direct inductive heating in the reaction zone. The heating is obtained by passing an alternating current through a metallic coil located inside the reactor or by using induction heated catalyzed hardware in the shape of a ferromagnetic structure, which is coated with an oxide impregnated with the catalytically active phase.
US11059718B2	Methods and compositions using peptides and proteins with C-terminal elements Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
US11059713B1	Remote beverage selection with a beverage dispenser A beverage order fulfillment system allows for beverage fulfillment from a mobile device without requiring a custom software application on the mobile device but uses a web connection to control beverage dispenser operations instead. The mobile device incorporates web browser software, and the web browser software is configured to initiate communication sessions with the at least one server. Data entry options are displayed on the interactive GUI for the first computer to communicate beverage selection commands to the beverage dispensing software, via the at least one server, in a respective instance of beverage fulfillment. The at least one server incorporates web socket application program interfaces (APIs) stored on the at least one server and configured to connect a communications link to the beverage dispenser and the web browser software on the first computer.
US11059711B1	Portable beverage container systems and methods for adjusting the composition of a beverage A beverage apparatus, the beverage apparatus being hand-holdable by a user of the beverage apparatus to be portable, can include a beverage chamber housing that includes a chamber for storing a consumable liquid. The beverage apparatus can include a dispensing assembly that includes a receptacle. The receptacle can retain a vessel. The vessel can include an electronic tag and can contain an additive. The dispensing assembly can be operatively controllable by a controller to output the additive from the vessel into the consumable liquid. The beverage apparatus can include one or more sensors, devices, or assemblies that can be used to detect a volume of liquid in the chamber or a liquid level in the chamber. The beverage apparatus can include an apparatus processing portion (ACP) and an apparatus database portion.
US11059710B2	Rotary-type capping machine A rotary capping machine for containers with screw caps includes a central and fixedly mounted support around which a rotary carrier having capping arrangements can be driven to rotate rotation by a first motor. The capping arrangements have capping tools that can be lifted and lowered and that can be rotated by a second motor. Each has, on its underside, a capping head for receiving screw caps. The support central includes a bottom support, the top end of which is connected to a middle support that forms a bearing section and that has a rotary bearing. The middle support releasably connects to a top support, which releasably connects to a head plate. The drive gear's rotation axis and that of the first motor are parallel to the machine axis. The drive gear meshes with a crown gear formed on the rotary carrier. The second motor's drive gear is parallel to the machine axis and meshes with a crown gear formed on the control element.
US11059708B2	Grapple A grapple for mounting to a boom of a boom crane includes a body member for mounting to the end of a boom of a boom crane including a first wing member and a second wing member and opposing first and second jaw members. Each jaw is hingably coupled to the body member, and hinges with respect to the body member by the action of a hydraulic cylinder. A first end of the hydraulic cylinder is coupled to the jaw member and a second end of the hydraulic cylinder is coupled to a portion of one of the wing members. The first and second wing members extend to position the second end of each hydraulic cylinder rearward of an end of the boom of the boom crane or a coupling between the body member and the boom of the boom crane.
US11059703B2	Crane trolley A trolley of a crane is arranged to move along a main support structure of the crane. The trolley includes a support frame structure; bearing wheels fastened to the support frame structure and by means of which the trolley is arranged to move along the main support structure; a hoisting mechanism that has a rope drum for a hoisting rope; a rope pulley arrangement through which the hoisting rope may be guided from the rope drum to a fixed fastening point on the trolley; and a hoisting member in cooperation with the hoisting rope for hoisting a load. The rope drum is supported to the support frame structure of the trolley so that the axle of the rope drum is parallel to the main support structure. The rope pulley arrangement is located, in the axial direction of the rope drum, at least partly outside one rope drum end which is on the side of said fastening point. The support frame structure is divided into two separate frame parts, whereby the first frame part supports the rope pulley arrangement and the rope drum end on the side thereof, and whereby the second frame part supports the opposite end of the rope drum.
US11059690B2	Method and system for automated stacking and loading of wrapped facemasks into a carton in a manufacturing line An automated method and system for stacking and loading wrapped or unwrapped facemasks into a carton in a facemask production line includes conveying individual wrapped facemasks in a continuous stream to a stacking location. At the stacking location, the facemasks are deposited into a vertical accumulator such that the facemasks are stacked in the accumulator. Upon reaching a predetermined fill level of facemasks in the accumulator, a bottom retainer in the accumulator is opened such that the stacked facemasks drop into a carton placed below the accumulator. Upon opening the bottom retainer, a mid-level retainer is actuated in the accumulator that captures facemasks that continue to be deposited into the accumulator at an intermediate height above the bottom retainer. The bottom retainer is closed after the stacked facemasks drop into the carton, and the mid-level retainer is then opened such that the facemasks captured by the mid-level retainer drop onto the bottom retainer.
US11059688B2	Printer A printer includes a first route to which a sheet from a roll paper is to be fed, a drive roller arranged on the first route and capable of sending the sheet, an image forming part (thermal printer head), a second route branched from the first route, a route changer for switching a route of the sheet, a curl corrector provided on the second route, and a cutter (cutting unit) provided on the first route. The curl corrector is configured to form the route with a curl correction roller and a guide member, and an advancing direction of the route is changeable 100 degrees or more when the sheet passes through the curl corrector.
US11059687B2	Sheet supplying device A sheet supplying device includes: an air blow opening configured to blow air to a side portion of an uppermost part of stacked sheets; and a flow adjuster extending from above the air blow opening over an edge of a top sheet of the stacked sheets and configured to cause an air flow blown from the air blow opening to travel along an upper surface of the top sheet of the stacked sheets.
US11059686B2	Sheet storage apparatus and image forming apparatus An image forming apparatus includes a side regulating plate provided in a sheet feeding cassette and a regulating surface to regulate an end position of a sheet stored in the sheet feeding cassette. A first arm connected with a first connector of the side regulating plate and a second arm connected with a second connector of the side regulating plate pivot on an axis extending in the gravity direction, wherein the second connector is different from the first connector in terms of a feeding direction. A first fixing part fixes the first arm to the sheet feeding cassette, and a second fixing part fixes the second arm to the sheet feeding cassette, wherein the first arm intersects with the second arm when viewed in the gravity direction when the side regulating plate is located in at least a part of a movable range of the side regulating plate.
US11059685B2	Device for filling a container with particulate material The invention relates to a filling device (1) for filling a container with a particulate material (28). The filling device (1) comprises a supply container (2) that can be filled with the particulate material (28), wherein the supply container (2) has a lower opening (2.2). Moreover, the filling device (1) comprises a radial distribution unit (3), which can be supplied with the particulate material via the lower opening (2.2) of the supply container (2) and which is connected to the supply container (2) in such a way that it can rotate about a rotational axis (A), in order to distribute in the container the particulate material (28) supplied from the supply container (2) to the distribution unit (3). The filling device is characterized in that the distribution unit (3) can be driven by a drive unit (4) that is arranged outside the supply container (2).
US11059681B2	Systems and methods for pneumatic tube smart carrier tracking Systems and methods for tracking carriers and other critical path items are provided. The systems and methods comprise structure and functionality to allow for the real-time tracking of pneumatic tube smart carriers and other devices including the use of an IoT capable device, a computer, and an IoT access point. The present disclosure also provides monitoring and analytics capabilities to allow for complex information to be tracked. Such information includes, but is not limited to carrier velocity, air flow, and latch status of the carrier's door.
US11059677B2	Conveyor device Conveyor device (1) including an endless conveyor belt (4), a first drive (3) for driving the endless conveyor belt (4), a main frame (2) and an auxiliary frame (19) supported in the main frame (2), a second drive (15) for moving the auxiliary frame (19) back and forth relative to the main frame (2) in the manner of a shuttle-conveyor, such that a supply track (4a) of endless conveyor belt (4) supported by the auxiliary frame (19) can feed products (P) on a discharge track (4b) of endless conveyor belt (4) supported by the main frame (2).
US11059673B2	Conveyance system A conveyance system for conveying a workpiece to each of a plurality of processing apparatuses includes a track extending over the plurality of processing apparatuses and fixed to the upper portions of the processing apparatuses; an automated conveying vehicle for traveling on the track, the automated conveying vehicle including a storage member having a housing space for housing the workpiece therein, a traveling member coupled from above to the storage member, a traveling mechanism mounted on the traveling member, a lifting and lowering mechanism mounted on the traveling member, for lifting and lowering the storage member while suspending the storage member from above, and a receiver for receiving control signals.
US11059672B2	Article transport facility A fire protection door in an open position is present above a traveling path of a transport vehicle. The fire protection door is capable of moving downward from the open position to a closed position along a door trajectory. The transport vehicle includes: a control portion; an area detection portion that detects an interference area, which is an area in which a portion of the transport vehicle in the traveling path overlaps the door trajectory; and a descent detection portion that detects a descent of the fire protection door. The control portion performs a retraction control such that the transport vehicle travels to the outside of the interference area when the descent detection portion has detected a descent of the fire protection door in a state in which the transport vehicle is located in the interference area.
US11059669B2	Locking roller assemblies for roller conveyors Locking roller assemblies for locking and unlocking a roller of a roller conveyor. The disclosed locking roller assemblies include rollers that, by default, are locked from rotation in the absence of a transferred object such as a container, crate, or pallet. When an object is present over the roller, the roller is passively actuated by the object to unlock and release the roller, enabling the roller to rotate. When the package or article has passed by the roller, the locking roller assembly resumes the default configuration of locking the roller to prevent rotation. In some embodiments, actuation of the locking mechanism is parallel to the roller axis and accomplished by a lever and cam arrangement. In other embodiments, actuation of the locking mechanism is in a direction that is orthogonal to the roller axis and accomplished by a plunger arrangement.
US11059666B2	Large-capacity modular holding container and related methods A holding container includes a plurality of pre-formed, releasably interlocking, load-bearing panels configured to form an at least partially curved, load-bearing wall extending around the perimeter of at least one storage area capable of containing at least 100,000 gallons of liquids, solids or a combination thereof. At least one among the width and length of each panel is less than 102 inches in a non-load-bearing state.
US11059653B2	Insulating cup An insulating cup includes an outer body surrounding at least a portion of an inner body. The outer body folds inwardly and upwardly at the bottom end to form a distal fold that spaces the inner surface of the outer body at the bottom end away from the outer surface of the inner body. The outer body further includes an embossment across the majority of the length and width of the sidewall such that the inner surface of the outer body projects outwardly away from the inner body to space apart the inner surface of the outer body from the outer surface of the inner body in the location of the embossment. The distal fold and embossment separate the inner body and the outer body creating an insulating air space between substantially the entire inner surface of the outer body and the outer surface of the inner body.
US11059651B2	Thermally insulated container The present invention provides a thermally insulated shipping container comprising a thermally insulating layer defining a first void, a main layer containing phase change material (main PCM layer) within the first void and defining a second void within the first void, a barrier layer containing phase change material (barrier PCM layer) within the second void and distinct from the main PCM layer, the barrier PCM layer defining a third void within the second void, the container being arranged to receive a product for transportation inside of the third void, wherein the main PCM layer has an average thickness greater than the average thickness of the barrier PCM layer, the barrier PCM layer comprises of an envelope in which the phase change material of the barrier PCM layer is contained and the barrier PCM layer is configured to maintain the phase change material with a relatively even distribution within the envelope.
US11059647B2	Apparatus, systems and methods for identifying products Apparatus, systems and methods for identifying products are described herein.
US11059641B2	Dispenser for a flowable substance A dispenser has a bottle (2) and a closure (3) for the bottle (2). The closure (3) has abase (4) forming a dispensing outlet (6) and a flip-cap for openably closing the dispensing outlet (6). The base (4) is attached on the bottle (2). The dispenser (1) further having a hinge (7) which interconnects the flip-cap and the base (4) for swiveling the flip-cap relative to the base (4) between a closed position, in which the flip-cap closes the outlet (6), and an open position in which the outlet (6) is open. The hinge (7) forms a swivel axis. The closure (3) forms a first end (18, 19) in a direction toward the flip-cap and a second end (18, 19) in a direction toward the base (4). The closure (3) in an area between the hinge-level plane and the second end (18, 19) forms an outer surface circumferentially around the longitudinal axis which is at least partly provided by an outer surface of the base (4) and an outer surface of the flip-cap.
US11059637B2	Child resistant container system A child restraint container system has a hollow body elongated from a closed end to an open end and a cap that fits over the open end to seal the container. The cap is formed from a top portion and a bottom portion, each portion having a disc. Each disc has at least one ring of teeth configured to engage the teeth of the other disc. The interlocking disc allow the container to be sealed such that a child would be unable to remove the cap and open the container.
US11059636B2	Discharge container A discharge container includes: a double-walled container body including an inner layer body and an outer layer body; a discharge cap having a discharge outlet, the discharge cap being attached to a mouth of the double-walled container body; and a check valve structure. The check valve structure has a tubular partition wall defining a flow path of the content and a valve body which is provided on the partition wall with a hinge portion and has a single swing structure, and space inside the partition wall rather on the discharge outlet side than on the valve body side serves as a liquid reservoir space where part of remaining content is stored after the discharge of the content.
US11059635B2	Container with cap A container having a cylindrical pouring nozzle with an external thread and with a stop; a cap with an internal thread which can be screwed onto the external thread of the pouring nozzle as far as an end position in which the cap bears in the direction of rotation on the stop of the pouring nozzle; and a seal made of a material which is softer than a material of the cap and a material of the pouring nozzle. The seal is fixedly connected to the cap and has a first sealing element which, with the cap screwed on, is arranged in a radial direction between the cap and pouring nozzle and bears on a lateral surface portion of the pouring nozzle.
US11059634B2	Assemble and disassemble structure for container liner and liner locking device thereof An assemble and disassemble structure for container liner and liner locking device thereof, which provides a drinking container having a mineral liner that can be replaced through the assemble and disassemble structure. The assembly is provided with an outer cylindrical sleeve, the interior of which is a holding space. The outer circumference of the upper end of the outer cylindrical sleeve is a connecting end, and the mineral liner is inserted into the outer cylindrical sleeve. A connecting ring is provided with a clasping portion, and assembling the clasping portion to the outer cylindrical sleeve enables fixing the mineral liner in a stable position in the outer cylindrical sleeve. An elastic locking device locks the connecting ring at combining angular positions.
US11059632B2	Self-closing device A device (1) incorporated into in plastic material closure (7) for containers (4) featured by its novel arrangement. It consists of parallel vertical walls, preferably of square, rectangular section, or of another shape, with a tilting lid (3) inside. That lid, when at rest position (6), leans against the opposite vertical wall to determine the closing of the hole thanks to the symmetry between the walls and moves to an open position (8) when exerting pressure on the walls of the container (4). The closing position (6) is achieved when the pressure on the container stops.
US11059622B2	Bulk material shipping container A bulk material shipping container including a pallet, a compartment mounted on the pallet, a material unloading assembly, and a material loading assembly.
US11059621B2	Container with at least one compartment A container for holding one or more articles includes a plurality of panels for extending at least partially around an interior of the container. The plurality of panels includes a front panel, a back panel, at least one side panel, a bottom panel, and a divider panel separably connected to a panel of the plurality of panels. The divider panel is pivotable relative to the panel of the plurality of panels to define a compartment in the interior of the container.
US11059620B2	Container construction The invention is a bottle or container for a beverage, which is configured with an upper and lower compartment connected by a waist portion that defines a passage therebetween. Through the use of an appropriately configured freezing shelf, the beverage held in the lower compartment can be frozen at point of sale. The bottle is specifically configured to, upon activation, create a pinch point between the waist portion of the bottle and the punt of the lower compartment. This pinch point is achieved through controlled deformation of part of the lower compartment and/or waist portion of the bottle and effectively seals the lower compartment, and its contents, from the upper compartment, or at the very least significantly restricts the passage between the two compartments. Convection circulation between the two compartments is prevented or at least hindered. The isolation of the lower compartment from the upper compartment by virtue of the pinch point may leads to quicker crystallization and ice formation. The invention is advantageous it means that the beverage contained in the upper compartment can be held at a higher temperature and thus is easier to consume at the time of purchase and allowing some time for the beverage in the lower compartment to melt and in due course become consumable.
US11059619B2	Bottle can and bottle can with cap A bottle can has a curl part at an opening end of a mouth part thereof. The curl part has an upper end curved part in which an upper part of a neck shoulder part of the mouth part is curved outward and an outer wall part extending downward from the upper end curved part. A predetermined angle at which an outer edge side of a lower end face of the outer wall part opens is formed between the lower end face of the outer wall part and the neck shoulder part. An inner edge of the lower end face comes into contact with the neck shoulder part when a downward load is applied to the curl part from above.
US11059618B2	Apparatus for emptying a container and method of use An apparatus for emptying a container including a body unit, a container platform, a cutting blade, and a hold-down assembly. The body unit at least partially defines a chamber, and the container platform is configured to support a container. The cutting blade is movable between a retracted position and an extended position. The cutting blade is located within the chamber when in the extended position. The cutting blade is configured to puncture a container positioned on the container platform as the cutting blade goes from the retracted position to the extended position. The hold-down assembly is configured to secure a container positioned on the container platform. The hold-down assembly is oriented such that a bracket and a shaft of the hold-down assembly are fixed relative to the body unit when an adjustable strut of the hold-down assembly is in a locked strut configuration.
US11059615B2	Packaging machine with suction plate A packaging machine comprising a machine frame, at least one work station attached to the machine frame, and a transport device with a transfer unit for feeding trays to the work station, wherein the transfer unit comprises a suction plate for transporting trays in a predetermined transport plane. The suction plate may comprises at least one reception mold which is formed at least in part having the shape of an inner contour of an upper opening region of a tray facing it, provided to the reception mold for reception and transport, so that the reception mold during transport in the transport plane of the tray is arranged in a positive-fit manner in its upper opening region and aligns the tray in the transport plane in a predetermined position on the suction plate. The invention also relates to a method for supplying trays to a work station of a packaging machine.
US11059614B2	Insulation packaging system The present disclosure is directed to an insulation packaging system. The insulation packaging system includes a plurality of insulation packages with first ends and second ends. The plurality of insulation packages defining an axis. A first film wraps around the axis to compress and couple the plurality of insulation packages together, while a second film wraps around the first and second ends of the plurality of insulation packages. The first and second films are different films.
US11059611B2	Apparatus and method for compacting packages filled with bulk material A compacting device and method is provided for compacting bulk material in an open package, the compacting device including a poker compactor accommodated on a carrier device. The poker compactor includes a gas-permeable outer wall connected with a suction duct. The poker compactor is suitable to be inserted into an open package for the poker compactor to come into contact with the bulk material to degas and compact the bulk material in the open package. The poker compactor has a longitudinal axis around which it is pivotally accommodated.
US11059608B2	Earth to orbit transportation system Various embodiments of space launch vehicle systems and associated methods of manufacture and use are disclosed herein. In some embodiments, the systems include a reusable, horizontal takeoff/horizontal landing (HTHL), ground-assisted single-stage-to-orbit (SSTO) spaceplane that is capable of providing frequent deliveries of people and/or cargo to Low Earth Orbit (LEO). In some embodiments, the spaceplane can takeoff with the aid of a rocket-powered sled that, in addition to providing additional thrust for takeoff, can also provide propellant for the spaceplane engines during the takeoff run so that the spaceplane launches with full propellant tanks.
US11059604B2	Method of assembly of the structure of an aircraft and frame for carrying out said method A method for performing the assembly of an aircraft includes, once at least first and second templates (A, B) with through holes (a, b) have been defined on a chassis, taking an initial measurement of the templates to identify the positions of the different components; measuring a laser beam to know the real coordinates through which the laser beam passes through the holes (a, b), calculating the mathematical equation of the straight line of the laser beam in order to calculate its path and target points of the elements to be assembled, performing the mathematical calculation of the point where the laser beam must strike when the element is positioned in its theoretical position, calculating the target readings which the measurement apparatus has to show when the laser is in the target point, positioning the element to be assembled following the reading of the apparatus, and fixing the element.
US11059600B2	Fluidic propulsive system and thrust and lift generator for aerial vehicles A vehicle includes a main body and a gas generator producing a gas stream. At least one fore conduit and tail conduit are fluidly coupled to the generator. First and second fore ejectors are fluidly coupled to the at least one fore conduit. At least one tail ejector is fluidly coupled to the at least one tail conduit. The fore ejectors respectively include an outlet structure out of which gas from the at least one fore conduit flows. The at least one tail ejector includes an outlet structure out of which gas from the at least one tail conduit flows. First and second primary airfoil elements have leading edges respectively located directly downstream of the first and second fore ejectors. At least one secondary airfoil element has a leading edge located directly downstream of the outlet structure of the at least one tail ejector.
US11059596B2	System and method for reserve parachute deployment A trap system is presented for deployment of a reserve parachute. The trap system includes a trap line with a first end coupled to a main parachute and a trap attached to a surface of the container. The trap includes an outer perimeter to removably hold the trap line and an interior to removably hold the reserve bridle. A kit is also presented for converting a parachute container into an improved parachute container to deploy a reserve parachute. The kit includes an attachment to be secured to a surface of the parachute container. The attachment includes a trap line with a first end configured to be coupled to the first end of the RSL lanyard, and a trap secured to a region of the attachment, with an outer perimeter to removably hold a second end of the trap line and an interior to removably hold the reserve bridle.
US11059594B2	Integrated lightning protection and electrical de-icing for aerodynamic structures An example method includes: forming a conductive layer on at least a portion of a surface of a substrate, where the substrate comprises a composite material of an aerodynamic structure, and where the conductive layer is configured to provide a conductive path to conduct an electric current generated by a lightning strike to an electrically-grounded location; depositing an insulating layer on the conductive layer; removing one or more portions of the insulating layer to form respective gaps in the insulating layer and expose corresponding one or more portions of the conductive layer; and forming a resistive-heater layer on the insulating layer such that the resistive-heater layer fills the respective gaps in the insulating layer and contacts the corresponding one or more portions of the conductive layer, such that when electric power is provided to the conductive layer, the electric power is communicated to the resistive-heater layer thereby generating heat therefrom.
US11059593B2	Airflow management in cabin of aircraft Cabin air is managed in the aircraft as a function of the minimum requirements for defined air quality needs, temperature control needs, and cabin pressurization needs. Airflow may be varied dynamically as a function of aircraft or cabin altitude, and the minimum requirements for airflow may be determined in real time so as to dynamically set an airflow schedule.
US11059592B2	Coaxial fluid vent and electronic control for a fluid valve for aircraft A ventilation system for ventilating a passenger compartment of an aircraft, an aircraft, and a method of operating the ventilation system are disclosed herein. The ventilation system includes, but is not limited to, a bezel, a fluid vent, an electronic sensor, and a valve. The bezel defines a bezel aperture and the fluid vent defines an axis that passes through the bezel aperture to direct a stream of air through the bezel into the passenger compartment. The electronic sensor is associated with the bezel and is configured to generate a bezel position signal. The valve is configured to vary a flow rate of the stream of air through the fluid vent based on the bezel position signal.
US11059587B2	Seat back decoupler mechanism An aircraft passenger seat with dynamic seat back breakover including a pivotally-attached seat back element and a seat back breakover mechanism including an articulating weighted inertia linkage operable for coupling the seat back element in a first operating condition in which the seat back element is movable between an upright taxi takeoff and landing (TTOL) position and a reclined position, and decoupling the seat back element in a second operating condition to allow the seat back element to move forward past the upright position, the first operating condition corresponding to inertial loading below a predetermined threshold value and the second operating condition corresponding to inertial loading above the predetermined threshold value.
US11059580B2	Device for supplying power to a wired drone The present invention relates to a device for supplying electrical power to a wired system for a drone (1). The device according to the invention includes at least one power converter (4) on the ground and one power converter (2) at the level of the drone (1), regulation at the level of the converter on the ground ensures that the output voltage of the power converter (4) on the ground increases when the output current of the power converter (4) on the ground increases. The method according to the invention is intended for all wired drones, the wire (3) of which is used to supply electrical power to the drone (1).
US11059579B2	Universal flying terrain vehicle A universal aerial platform (11, 41) supports lift elements (13, 14), thrusters (15), landing gear (21, 22) and a fuel supply (16) and has a coupling mechanism (17) external to the aerial platform for coupling to a terrain vehicle (20) so as to convert any suitably adapted terrain vehicle to a flying vehicle (10, 40). The terrain vehicle forms the cockpit of the flying vehicle. The terrain vehicle (20) includes flight controls that are automatically coupled to the airplane structure either wirelessly or by wires when the terrain vehicle is coupled thereto.
US11059578B2	Kite control bar with integrated back trim line tensioning means A kite control bar having a tensioning member anchored to the bar end float and secured to the trim line. The tensioning member is capable of expanding and contracting. The tensioning member has a default state which is either an expanded state or a contracted state. When an adjusting force is exerted upon the trim line, the tensioning member is drawn into another of the expanded state or the contracted state. When the adjusting force is released, the tensioning member tends to return to the default state. This biases the trim line to force excess trim line out of the bar end float.
US11059572B2	Landing gear An aircraft landing gear 2 is disclosed having a first arm 6a configured to have one or more wheels 8a mounted at one end, the first arm 6a being configured for mounting to a pivot 10a. The landing gear 2 includes a second arm 6b configured to have one or more wheels 8b mounted at one end, the second arm 6b being configured for mounting to a pivot 10b. The landing gear 2 further includes a first link 18a pivotally coupled to the first arm 6a, a second link 18b pivotally coupled to the second arm 6b; and a main link 20 pivotally coupled to each of the first and second links 18a, 18b and to a shock absorber 22 arranged to provide a biasing force via (i) the main linkage 20 and the first link 18a which opposes rotation of the first arm 6a about the pivot 10a and (ii) the main linkage 20 and the second link 18b which opposes rotation of the second arm 6b about the pivot 10b.
US11059569B1	Flight control system for aircraft having multi-functional flight control surface A flight control system for an aircraft having a multi-functional flight control surface. The aircraft has at least one multi-functional flight control surface formed by a sequence of flaps. The shape of each multi-functional flight control surface may be configured by a flight control to simultaneously adjust a trajectory of the aircraft in two or more of a pitch direction, a roll direction, and a yaw direction. The flight control for operating said the multi-functional flight control surface responds to both pilot commands and machine-generated commands. The machine-generated commands configure the shape of the surface of each multi-functional flight control surface in real-time based, at least in part, upon a set of flight objectives comprising: (a) minimizing drag of the aircraft, (b) aeroelastic modal suppression for the aircraft, and (c) maneuver load alleviation in the aircraft.
US11059564B2	Automated deployable fences for aircraft wings Automated deployable fences for aircraft wings are described. An example apparatus includes a fence, a latching actuator, and a biasing actuator. The fence is coupled to a wing of an aircraft. The fence is movable relative to the wing between a stowed position in which a panel of the fence extends along a skin of the wing, and a deployed position in which the panel extends at an upward angle away from the skin. The panel impedes a spanwise airflow along the wing when the fence is in the deployed position. The latching actuator is movable between a first position in which the latching actuator maintains the fence in the stowed position, and a second position in which the latching actuator releases the fence from the stowed position. The latching actuator moves from the first position to the second position in response to a control signal received at the latching actuator. The biasing actuator moves the fence from the stowed position to the deployed position in response to the latching actuator moving from the first position to the second position.
US11059559B2	Acoustic liners with oblique cellular structures The present disclosure provides acoustic structures and related systems and methods which may be used to dampen or attenuate sound waves, including, for example, noise generated by or emanating from various aspects or components of turbomachines such as turbine engines. These acoustic structures include oblique polyhedral cellular structures, including converging polyhedral cells and diverging polyhedral cells, and related systems and methods of making and using such acoustic structures.
US11059555B2	Trolling motor latching system A mounting assembly for improved latching of a watercraft trolling motor that includes a shaft assembly. The mounting assembly includes a pivot joint configured to be fixed relative to the watercraft. The mounting assembly further includes a swinging bracket assembly having: (a) a swinging bracket having a first end, a second end and a length, the first end being configured for attachment to the shaft assembly and the second end being rotatably attached to the pivot joint; and (b) a latch pin assembly including an elastic element and a latch pin mounted to the swinging bracket. The mounting assembly still further includes a stationary bracket configured to be fixed relative to the watercraft and having a protuberance and a sloped surface receiving the latch pin. Inadvertent removal of the latch pin from a sliding, latched relationship with the sloped surface is obstructed by the protuberance.
US11059550B2	Diving computer with coupled antenna and water contact assembly A diving computer with coupled antenna and a water contact assembly is disclosed. The diving computer has at least one radiator element located on or connected to an outermost surface of a bezel of the diving computer and a radio unit having a conductive coupling to said radiator element, for enabling wireless communication between said diving computer and external devices. A conductive water contact surface extends through the housing of the diving computer and a water contact detector circuit is arranged, as a part of an underwater condition sensing circuit, to sense an underwater condition of the device. When water establishes a current path through said underwater condition sensing circuit from the water contact surface to ground, the sensing circuit provides an indication of an underwater condition to the diving computer.
US11059537B2	Bicycle controller and bicycle control system including bicycle controller A bicycle control device includes an electronic controller that controls a motor, which assists propulsion of a bicycle. The electronic controller is configured to decrease an output of the motor to less than or equal to a limit value upon determining a shifting device is performing a shifting action to change a transmission ratio of the bicycle. The electronic controller is further configured to change at least one of the limit value of the output of the motor and a time in which the output of the motor is decreased upon determining the shifting device is performing the shifting action in accordance with at least one of an actuation state of the shifting device in the shifting action and a parameter of the bicycle that is changed by the shifting action performed by the shifting device.
US11059535B1	Mechanism for adjusting backrest of a motorcycle The present invention is a mechanism for adjusting backrest of a seat of a motorcycle that moves backrest towards and away from seat thereby adjusting sitting space as desired for different users. The mechanism includes a connecting bracket and a sliding bracket. Connecting bracket connects backrest and central bracket which is a part of the motorcycle that conventionally connects backrest to fender bracket disposed on a fender. Sliding bracket is connected at a bottom portion of central bracket and slides on fender bracket. When sliding bracket slides, central bracket and connecting bracket slides, thereby sliding backrest towards and away from seat of motorcycle. Thus, as desired space between backrest and seat can be increased or reduced to provide comfortable sitting on seat.
US11059531B2	Magnetic roller A magnetic roller for being rotatable on a ferromagnetic surface is provided. The magnetic roller includes a roller wheel having an inner space, a magnetic array arrangement and at least one first drive mechanism. Further, the magnetic array arrangement is adapted to be swivelably disposed within the inner space of the roller wheel. The magnetic array arrangement includes a strong adhesion force side and a weak adhesion force side. Furthermore, the first drive mechanism is configured to swivelably drive the magnetic array arrangement. The first drive mechanism swivelably drive the magnetic array arrangement to direct the strong adhesion force side towards the oncoming ferromagnetic surface, and, to direct the weak adhesion force side towards the foregoing ferromagnetic surface to enable the roller wheel to move forward on the ferromagnetic surface.
US11059524B2	Vehicular panel structure A vehicular panel structure includes a panel, a reinforcement disposed inward of the panel in a vehicle, and mastic that bonds the panel and the reinforcement to each other. The reinforcement is provided with a body portion constituting a middle portion in a longitudinal direction and having a linear expansion coefficient smaller than the linear expansion coefficient of the panel, a connection portion constituting an end portion in the longitudinal direction, and a joining portion allowing the body portion and the connection portion to be joined to each other by a thermosetting adhesive and a fastener. A long hole portion is disposed in the reinforcement and is formed in either the connection portion or the body portion. The fastener is inserted into the long hole portion.
US11059523B2	Adjustable datum pin assembly for temporarily securing a vehicle component to a vehicle structure An adjustable datum pin assembly for temporarily affixing a bumper cover, fender, side panel, roof spoiler, or the like (i.e., a vehicle component) to an associated vehicle structure, the adjustable datum pin assembly including: a fixed lower portion adapted to be coupled to the associated vehicle structure; a translatable upper portion translatably coupled to the fixed lower portion, wherein the translatable upper portion includes an attachment structure adapted to be coupled to the bumper cover, fender, side panel, roof spoiler, or the like; and a friction mechanism disposed between the translatable upper portion and the fixed lower portion adapted to resist translation of the translatable upper portion with respect to the fixed lower portion.
US11059520B2	Monobloc part forming a front bloc comprising an absorption system and an aerodynamic system The invention relates to a monobloc part forming a front block for motor vehicle including a structural portion forming an energy absorption system, and a moulded semi-structural portion forming at least an aerodynamic system, the semi-structural portion being overmoulded on the structural portion.
US11059509B2	Ridable kart A ridable kart can have a body that supports a front wheel and movable rear wheels. The kart can include a motor that supports and drives the rear wheels. The motor and rear wheels are configured to tilt and rotate relative to the body of the kart. The body of the kart includes a concave space in which the front and rear wheels are positioned so that they are at least partially concealed by the body when viewed from the side of the kart.
US11059508B1	Shopping cart assist handles Auxiliary handles for attachment to a shopping cart to serve as supports for persons with limited mobility or who tire easily while shopping. The handles are used in pairs, with each handle having a generally vertical or upwardly directed telescopically extendable upper tubular member extendable from a lower tubular member, rigidly attachable to a structural supporting member on the shopping cart. This upper tubular member is topped with a horizontal tube that extends over the back of the cart and also in an outwardly direction past the back of the cart so as to serve as an armrest or handrest for the user as the user walks along behind the cart, pushing the cart while shopping. The user can lean on the handles to ease his or her weight on his or her knees, legs, ankles, and back, to make use of the cart and shopping less tiresome.
US11059507B2	Transport trolley The invention relates to a stackable transport trolley, in particular a stackable shopping trolley, comprising a chassis and a basket; the chassis includes a support frame and a frame of rods which is arranged on the support frame, the frame of rods supporting the basket.
US11059504B2	Technologies for caddy assemblies A container system including a storage base that includes a frame and a partition wall dividing the frame into first and second compartments, where each of the first and second compartments includes a cavity formed therein and the partition wall is formed to include a handle, and the handle is configured to removeably couple a first and second storage base to form a storage unit.
US11059503B2	Systems and methods for rail worker and rail vehicle warning and position determination System and methods are provided for warning a worker of a rail vehicle, or an operator of the rail vehicle of the worker. The system includes a worker device, a vehicle device, and a central server. The devices and server operate on one or a combination of actual or simulated satellite navigational signals, and beacon signals to determine the position of the devices, to generate a warning. The position determination may prioritize beacon signals over satellite navigation signals. The position determination may involve correcting a calculated position based on a measured power level of the beacon signal received from the beacon transmitter, an elapsed time since a previous beacon signal was last received by the device from the beacon transmitter, an elapsed time since a previous satellite navigation signal was received by the device, or an accuracy of the position of the device based on the satellite navigation signal.
US11059489B2	Methods and systems for detecting road surface conditions The present disclosure relates to detecting road surface conditions. A road surface detector comprises a transmitter, receiver, and one or more processors. The transmitter is configured to transmit one or more radio frequency (RF) beams at a road surface. The receiver is configured to receive RF reflections of the one or more transmitted RF beams at two or more receive channels. The one or more processors are to determine a road surface condition based on a doppler signature of the received RF reflections. A method comprises transmitting one or more radio frequency (RF) beams at a road surface. RF reflections of the one or more transmitted RF beams are receives at two or more receive channels. The method includes determining a road surface condition based on a doppler signature of the received RF reflections.
US11059488B2	Control device of vehicle A control device of a vehicle including an engine, a power transmission device, a shift operation device, and a switching device includes: a shift-switching control portion outputting the control command signal when it is determined that the shift switching is permitted, and not outputting the control command signal when it is determined that the shift switching is prohibited, at the time of a shift switching operation; and an engine-starting control portion outputting a first signal causing the shift-switching control portion to determine that the shift switching is prohibited and initiating starting of the engine after determining that the shift switching is not being performed when it is determined that the shift switching is permitted at the time of an engine starting operation performed by the driver for starting the engine, and immediately initiating the engine when it is determined that the shift switching is prohibited.
US11059480B2	Collision avoidance system with elevation compensation A propulsion and collision avoidance system is associated with a machine operating on the ground, and is configured to determine whether a collision will occur based upon the pose and movement of the machine and the pose of the obstacle. The slope of a straight line between the machine and the obstacle is determined based upon the pose of the machine and the pose of the obstacle, and the slope of the straight line is compared to a slope threshold. A collision alert is generated after determining that a collision will occur and when the slope of the straight line is less than the slope threshold, and continuing propulsion commands are generated to propel the machine along the work surface after determining that a collision will occur and when the slope of the straight line is greater than the slope threshold.
US11059477B2	Parking assist device for vehicle The purpose of the present invention is to provide a parking assist device for a vehicle such that the vehicle can be parked without decreasing or excessively increasing the speed or causing the vehicle to stop during assisted parking, the speed of the host vehicle is kept constant even immediately after an obstacle or a bump is cleared, and the vehicle is prevented from colliding with any other parked vehicle. The device calculates a speed command value and/or an engine torque command value in consideration of the acceleration/deceleration of the vehicle and controls the speed of the vehicle on the basis of the calculated speed command value and/or the engine torque command value, said acceleration/deceleration being predicted in advance on the basis of the height and distance of an obstacle and/or a bump that is present in a parking path, the gradient of the road surface, and the steering angle.
US11059476B2	Method of controlling gear shift in neutral gear stage in hybrid electric vehicle A method of controlling a gear shifting in a neutral gear stage for shortening a gear shifting time in the neutral gear stage when performing a gear shifting of a hybrid electric vehicle is characterized in that when a shift class of the gear shifting is determined, a hybrid control unit of the vehicle determines a shift gear ratio in the N-stage in a current state by use of a transmission (TM) output speed and a transmission (TM) input speed at a class transition time point, determines an N-stage gear shifting progressing rate by use of the determined N-stage shift gear ratio, sets time points of a start and an end of the gear shifting based on the determined gear shifting progressing rate, and controls the gear shifting speed in the N-stage with reference to a gear shifting target speed and the transmission input speed in a section of the time points of the start and the end of the speed control.
US11059472B2	Control device of vehicle and control method of vehicle A control device of a vehicle includes a motor controller. The motor controller is capable of controlling a motor configured to generate a driving force of the vehicle, and switching between a first driving mode for driving the motor while using a continuous rated torque as an upper limit and a second driving mode for driving the motor while using a maximum rated torque as an upper limit, the continuous rated torque being lower than the maximum rated torque generatable by the motor. The motor controller drives the motor in the first driving mode in a case where a driver does not specify a driving mode.
US11059464B2	Method for controlling a hydraulic braking system in a vehicle In a method for controlling a hydraulic braking system, in the event of a failure of a primary brake actuator system, a secondary brake actuator system is activated.
US11059463B2	Control device display indicators for one-pedal function and automatic brake hold function A control device configured to control a vehicle is provided. The device comprises: a traveling control unit capable of executing stop hold control in an automatic brake hold function and a one-pedal function; and an output control unit capable of displaying a first indicator indicating that the one-pedal function is enabled and a second indicator indicating that the automatic brake hold function is enabled. The traveling control unit exclusively executes the automatic brake hold function and the one-pedal function. The output control unit executes at least one of ending display of the second indicator and displaying the first indicator when the one-pedal function is enabled instead of the automatic brake hold function and/or ending display of the first indicator and displaying the second indicator when the automatic brake hold function is enabled instead of the one-pedal function.
US11059462B2	Method and device for controlling a movement of a vehicle, and vehicle movement control system A method, device and control system for controlling vehicle movement, including: reading-in the specification data from an interface with a generating apparatus, the vehicle having a vehicle movement control system having the generating apparatus for generating specification data for the vehicle movement, at least one providing apparatus for providing vehicle property(s) and an actuator element for influencing the vehicle movement, the specification data representing a driving corridor/speed profile for a route section, and the at least one vehicle property from an interface with the at least one providing apparatus; determining vehicle guide data using the specification data and the vehicle property(s), the guide data being for controlling the vehicle movement while complying with the specification data; acquiring at least one manipulated variable for the at least one actuator element using the guide data; and outputting the at least one manipulated variable to an interface with the actuator element.
US11059461B2	Electrically coupled powered landing gear A powered landing gear mounted to a trailer includes an electrical connector mounted to the trailer that is configured to receive a jumper cable connected to a truck for supplying electrical power to the trailer, with a wiring harness mounted to the trailer that is electrically coupled to the connector. A landing gear includes a housing member, a telescoping leg member, a gear assembly configured to extend and retract the leg member relative to the housing member, and a drive system including a drive motor operatively engaged with the gear assembly, with the landing gear being operatively powered by electricity provided through the connector and wiring harness from the truck. The wiring harness may be operatively electrically coupled to the drive motor and/or a rechargeable power supply that is in turn electrically coupled to the drive motor, including through a controller.
US11059452B2	Seatbelt pretensioning retractor assembly including a gas release opening A seatbelt pretensioning retractor assembly for use in a vehicle is provided. The pretensioning assembly includes a tube in fluid communication with a gas generator and a driving element disposed therein that travels in a first direction in response to actuation of the gas generator. The driving element includes a polymer rod. A stopper is coupled to an end portion of the polymer rod. In one example, a seal member disposed between the gas generator and the stopper includes a head section and a skirt section. In another example, the tube has an opening that is adjacent to an exit to facilitate venting gas from the gas generator.
US11059449B2	Roof-mounted occupant restraint system A restraint system (10) for helping to protect an occupant (60) of a vehicle (20) having a roof (32) and a cabin (40) with a seat (50) for the occupant (60) includes an airbag (70) mounted to the vehicle roof (32). The airbag (70) has a stored condition and is inflatable to a deployed condition. The airbag (70), when deployed, extends from an upper end (90) connected to the vehicle roof (32) to a lower end (92) positioned adjacent the occupant (60). The airbag (70) has a U-shaped configuration including a first leg (104) and a second leg (106) pivotable relative to the first leg (104) in response to occupant (60) penetration into the second leg (106). A tether (120) has first and second ends (122, 124) each connected to the airbag (70) for limiting pivotal movement of the second leg (106) relative to the first leg (104).
US11059448B2	Curtain airbag assembly A present implementation of an airbag system is adapted to include a curtain airbag assembly having a vertical barrier extended in a vertical direction when deployed, the vertical barrier having a first inflatable part deployed at a left side of a vehicle and a second inflatable deployed at a right side of the vehicle. The airbag system further includes sensors adapted to sense parameters associated with operational characteristics of a vehicle and an electronic control unit (ECU) adapted to receive the parameters from the sensors. The ECU is further adapted to monitor the plurality of parameters to determine if the vehicle is experiencing an accident. The airbag system further includes an inflation module adapted to deploy the curtain airbag assembly. If the ECU determines that an accident is occurring, the ECU provides a trigger signal to the inflation module to initiate a process to deploy the curtain airbag assembly.
US11059440B2	System and method for automatically learning and recalling driver preferences A vehicle for automatically learning and recalling driver preferences includes a subsystem and a processor. The processor builds, for a user profile, an ideal range in which the subsystem has been adjusted over key cycles. For each instance in which the user profile is loaded, the processor causes the subsystem to adjust to the latest saved user adjustment of the subsystem. The processor save the current user adjustment in response to the current user adjustment of the subsystem being within the ideal range.
US11059439B2	In-vehicle power supply device An in-vehicle power supply device according to the present disclosure includes an input terminal, a charge-discharge circuit connected to the input terminal, a first output terminal connected to the charge-discharge circuit via a first switch unit and a first cut-off unit, a second output terminal connected to the charge-discharge circuit via a second switch unit and a second cut-off unit, and a controller connected to the input terminal, the first output terminal, and the second output terminal. The controller controls the charge-discharge circuit, the first switch unit, the first cut-off unit, the second switch unit, and the second cut-off unit. When the controller detects that a voltage of the first output terminal becomes lower than the first load threshold voltage, the first cut-off unit changes from a connected state to a cut-off state. After a lapse of a first predetermined period following a time at which the controller detects that the voltage of the first output terminal is lower than the first load threshold voltage, the second switch unit switches from a state of higher-resistance conduction to a state of lower-resistance conduction in which a resistance level is lower than the resistance level in the state of higher-resistance conduction.
US11059435B2	Vehicle software control device Disclosed is a vehicle software control device which includes hardware, a kernel connected to the hardware and configured to execute a first operating system, a system library connected to the kernel, a first connecting unit configured to connect a library for a second operating system different from the first operating system to the system library, and a first application executed on the second operating system.
US11059428B1	Bike rack attached to vehicle A bicycle rack that allows for easy installation and removable onto a vehicle and also easy loading and unloading of bicycle(s). A vertical arm contains a plurality of mounting pins each of which is configured to receive a mounting coupler. A mounting coupler wraps around a bicycle (for example around the bicycle top tube) and secures the bicycle to the mounting coupler via Velcro. The mounting coupler is then inserted onto one of the plurality of mounting pins which holds the bicycle onto the bicycle rack. The bicycle rack can hold numerous bicycles in this manner. In order to remove a bicycle, the mounting coupler can be released from its respective mounting pin.
US11059427B2	Storage box latch with a remotely located mechanical push button A storage bin assembly for vehicles includes a bin and a door. The door includes a latch-engaging surface that moves from a rest position when the door is opened. A latch pawl engages the latch-engaging surface of the door to prevent movement of the door to the open position when the latch pawl is in an engaged position. A push button actuator is disposed in a center portion of a dashboard structure. The push button actuator includes a cam surface that slidably engages the latch pawl and causes the latch pawl to move from the engaged position to a disengaged position to thereby unlatch the door.
US11059424B2	Package stablizing device A package stabilizing device for use in transporting a package in a vehicle includes a bracket assembly that is configured to couple to an element of a vehicle so that an arm of the bracket assembly extends into an interior space of the vehicle. A sling is coupled to and extends from a distal limit of the arm. The sling is configured to position a package so that the package is suspended within the interior space. The sling is configured to swing within the interior space to diminish forces that are applied to contents of the package as the vehicle traverses an uneven surface, accelerates, brakes, and turns.
US11059418B2	Multi-mode NVIS-compatible lighting system The present disclosure provides a night vision imaging system (NVIS) lighting system, comprising a frame comprising a first light source, a second light source adjacent to the first light source, a third light source adjacent to the second light source, and a diffuser mounted to the frame and encasing the first light source, the second light source, and the third light source. The first light source may comprise a first dominant wavelength, the second light source may comprise a second dominant wavelength different from the first dominant wavelength, and the third light source may comprise a third dominant wavelength different from the first dominant wavelength and the second dominant wavelength. Light emitted from the first light source, the second light source, and the third light source may be blended to generate a first blended light source comprising a first target output color.
US11059417B2	Driver monitor camera to control lighting features A disclosed light activation system includes a movable lighting element movable to adjust a direction of light, an actuator for moving the movable lighting element, a driver detection device and a controller configured to command operation of the actuator for moving the movable lighting element based on a detected direction of sight of the driver. A disclosed method of operating a vehicle lighting system includes monitoring a direction that a driver of a motor vehicle is looking, determining a lighting element within a region corresponding with the direction the driver is looking, and actuating a lighting element within the region based in response to the determined direction that the driver is looking and in response to a secondary condition being fulfilled.
US11059412B2	Multi-container side emptying liquid containing drill cuttings transport trailer A transport trailer and method specifically adapted for safely transporting liquid containing unstabilized drilling waste from more than one waste generator or, multiple waste streams from one or more waste generators. Typically drilling waste is stabilized using binding agents like fly-ash, liquids absorbing pellets or sawdust. In many jurisdictions binding agents are required to stabilize the drill cuttings prior to transport. A sealed transport trailer comprising greater than one container on the transport trailer is described herein which is specifically designed, sized and positioned over a set of axles so as to provide for safe, non-spilling transport, and particular ease of emptying for unstabilized drilling waste.
US11059409B2	Methods and systems associated with a mobile bin tipper A mobile bin tipper that is configured to receive, lift, and rotate a bin. The mobile bin tipper quickly and efficiently empty the content of bins into larger containers.
US11059408B2	Mortuary cargo loading system and method A mortuary cargo loading system having a transport bed adjacent to a motorized winch, a cable engaged with and extending from the motorized winch, a cargo stopper comprising a first end, a second end, and a guide therebetween, and a cargo stopper support having at least one bore for receiving a cargo stopper. The mortuary cargo loading system further has the cargo stopper support and the motorized winch connected to a surface of a vehicle cargo space, the first end of the cargo stopper is engaged with the at least one bore, the cable is engaged with the guide, and the transport bed is connected to the cargo stopper support.
US11059406B1	Head restraint with auxilary power A seat assembly for an automobile includes a seat back, a sleeve mounted within the seat back, a head restraint, the head restraint including a support post extending therefrom, the sleeve adapted to receive the support post to support the head restraint on the seat back, and a guide cap mounted onto the sleeve adjacent an external surface of the seat back, the guide cap including an electrical port.
US11059402B2	Conveyance seat The number of components required to restrict the movement of an operating section, when a cushion frame is moved in the height direction, and a link member, which is for moving the cushion frame, is reduced. The seat is provided with: a drive link that is rotatably attached to the cushion frame and that moves the cushion frame in the height direction according to rotation thereof; a gear part that engages with the drive link and that rotates the drive link; a link-rotation restricting member for restricting the rotation range of the drive link; an operating section that accepts an operation for adjusting the height of the cushion frame; and a rotation application section for rotating the drive link via the gear part according to the operating section. The movement of the operating section is restricted as a result of the link-rotation restricting member abutting against the rotation application section.
US11059401B2	Seat back A seat back configured to support a back of a seated person includes a back frame constituting an internal framework; and an elastic mat fitted to the back frame so as to cover the back frame from a front side, the elastic mat having a planar shape and being configured to elastically support the back of the seated person. The back frame includes a frame body and a support wire that protrudes forward from the frame body. The elastic mat includes a main support portion configured to support the back of the seated person, and a band portion that extends from a back surface of the main support portion, the band portion being wound around the support wire. The elastic mat has a through-hole through which a head at a distal end of the wound band portion is inserted such that the head is snap-fitted in the through-hole.
US11059400B2	Vehicle seat console A vehicle seat console has at least one vehicle-mounted guiding element, at least one seat-mounted guiding element that runs parallel to the vehicle-mounted guiding element, and a longitudinal adjustment mechanism on which a driving device acts via a transmission mechanism and which is designed to cause a relative adjustment between the vehicle-mounted guiding element and the seat-mounted guiding element. The vehicle seat console is characterized in that the longitudinal adjustment mechanism and/or the transmission mechanism is/are equipped with at least one energy absorption device which is configured to dampen abrupt relative movements between the vehicle-mounted guiding element and the seat-mounted guiding element.
US11059398B2	Discontinuous recliner for a vehicle seat A discontinuous recliner for a vehicle seat is provided. The discontinuous recliner comprises one or more locking pawls and a single actuating element which is configured to drive the locking pawl(s) both from the locking position to the unlocking position and from the unlocking position to the locking position. Thanks to the provision of the single actuating element, the overall number of components of the discontinuous recliner is significantly reduced. This allows to obtain a discontinuous recliner which is lighter, easier to be assembled and more reliable.
US11059394B2	Vehicle seat structural component, vehicle seat and method for manufacturing a vehicle seat structural component A vehicle seat structural component comprises a transverse tube and a structural element, in particular a vehicle seat side frame element the transverse tube is connected to the structural element in a connecting region. The structural element comprises a conical sleeve the structural is arranged captively in axial direction between deformed sections. One section is a curling wherein the conical sleeve is also arranged captively in radial direction.
US11059392B1	Push button mechanical seat adjustment controls An apparatus for moving a seat cushion of a seat on which the operator sits includes a seat frame and a pan supporting the seat cushion that is movably supported on the seat frame for movement relative to the seat frame, such as forward-backward or tilting movement. A control panel is mounted to the pan at a forward end of the pan and accessible by the operator while seated on the seat cushion. The control panel includes a housing defining a ledge that is configured so that the operator can grasp underneath the ledge with the operator's hand, with the thumb at an upper face of the control panel. An actuator button is supported on the housing at the upper face of the control panel for actuation by the thumb of the operator while grasping the ledge. A mechanism is connected to the actuator button and is configured and operable upon actuation of the actuator button to permit movement of the pan relative to said seat frame. In one embodiment, two push buttons are provided connected to corresponding extension and tilt mechanisms.
US11059391B2	Vehicle seat slide device A vehicle seat slide device includes an upper rail, a lower rail, a lock mechanism, and a lock release mechanism. The lock mechanism restricts relative movement of the upper rail. The upper rail includes two side walls and an upper wall. The lock release mechanism includes a lever member, a push portion, and a spring member. The push portion pushes an unlock element of the lock mechanism and performs an unlocking action with the lock mechanism when the lever member is pivoted based on an operation force. The spring member applies an urging force to the lever member in a direction opposite to the direction in which the lever member is pivoted. The spring member includes an engagement end, which engages the lever member, and a spring body. At least the spring body is arranged in an inner space of the upper rail defined below the upper wall.
US11059388B2	Vehicle seat A vehicle seat comprising: a seat cushion; a seat back; an actuator capable of changing an orientation of the seat back laterally by moving a pressure-receiving member; and a controller configured to exercise control over the actuator. The controller includes a posture control unit configured to execute, during turning of a vehicle, a seat posture control under which the actuator is caused to move the pressure-receiving member from an initial position to an advanced position to cause the seat back to orient toward a turning direction. The posture control unit is configured to activate, when an execution time of the seat posture control has become equal to or greater than an execution time threshold value, a control under which the actuator is caused to move the pressure-receiving member from the advanced position to an intermediate position to reversely change the orientation of the seat back.
US11059387B2	Method for cooling a traction battery of an electrically drivable vehicle, and cooling arrangement for carrying out the method In a method for cooling a traction battery of an electrically drivable vehicle, a refrigerant is used as cooling medium, and in a mass flow of specified magnitude is led along the traction battery through at least one channel. The at least one channel is in heat-conducting connection with the traction battery. It is proposed that an available cooling power (PV) for cooling the traction battery is determined, wherein as a function of the available cooling power (PV), the magnitude of the mass flow of the refrigerant is regulated in such a way that either no cooling power (Pactual) is delivered to the traction battery, or the delivered cooling power (Pactual) in each case assumes one of multiple cooling power stages (I, II) as a function of the available cooling power (PV).
US11059382B2	Battery box replacement system A battery pack replacement and explosion-proof system: Start to control the second battery pack robot system and the ferry robot to uninstall and install the first battery pack and the second battery pack; the second connection point of the first power supply protector's grounding conductor unloads and absorbs the large current entering along the first power line; the third connection point unloads and absorbs the large current along the second power line; the fifth connection point of the second power surge protector unloads and absorbs the large current along the third power line; the sixth connection point unloads and absorbs the large current along the fourth power line; the first connection point and the fourth connection point unloads and absorbs the large current along the first and the second control line and signal lines of BMS, various parts of the grounding conduct currents into the earth through the conductive tyre.
US11059381B2	Controlling electric vehicle charging currents According to an aspect, there is provided a computer device configured to control charging currents of at least a first charging station of an electric vehicle and at least a second charging station of an electric vehicle by internet based communications, wherein the charging stations are from different manufacturers, and wherein the charging stations are wirelessly coupled to the computer device.
US11059379B2	Position alignment apparatus and method for wireless charging A position alignment method for wireless charging performed by a VA for position alignment with a target GA is provided. The method includes identifying states of a plurality of GAs via wireless communication with an SECC that operates the plurality of GAs and receiving, from the SECC, information regarding one or more available GAs of the plurality of GAs. A target GA based is selected on the information regarding available GAs and a wireless communication association with the target GA is performed. A procedure for position alignment approval and a procedure for authentication is executed by a request to the SECC and in response to determining that the authentication is successful, position alignment with the target GA using LF signals is performed, wherein LF signals assigned to each GA are distinguished from LF signals assigned to other GAs in a TDM scheme.
US11059374B2	Hybrid vehicle control apparatus and hybrid vehicle The present invention is to make it possible to effectively recover regenerative energy and improve a fuel efficiency. Thus, there is provided an HCM 50 of a hybrid vehicle, in which the hybrid vehicle includes: an engine; a drive wheel to which a driving force of the engine is transmittable; a motor to which the driving force from the engine is transmittable and which is capable of transmitting a driving force to the drive wheel; and a battery which supplies power for driving the motor and stores power generated by the motor. The HCM 50 is configured to include: a high efficiency range information storage unit 53 that stores information specifying a high efficiency range in which an engine efficiency of the engine is high in an engine characteristic of the engine; a power generation amount measurement unit 51 that measures a low efficiency range power generation amount, which is an amount of power generated by the motor and stored in the battery when the engine operates in a low efficiency range being out of the high efficiency range; and an integrated control unit 52 that controls power of the low efficiency range power generation amount to be supplied from the battery to the motor when it is necessary to supply power for driving the motor.
US11059370B2	System and method for fault handling in a propulsion system for an electric vehicle A propulsion system for an electric vehicle comprising a high voltage battery unit having a first high voltage battery connected in series with a second high voltage battery and one or more power inverters arranged to connect the battery banks to one or more electric machines. The one or more power inverters and the one or more electric machines are configured to form a first and a second three-phase system, and the system and method relates to fault handling if a fault is detected in one of the first and second three-phase system. The architecture incorporating dual battery banks, and dual and/or multiphase inverters and electric machines can provide enhanced redundancy and limp home functionality in cases where a fault or error occurs in the inverter and/or in the electric machine so that a faulty three-phase system can be operated in a safe pulse-off mode.
US11059365B2	Drive device for a hybrid-driven motor vehicle, and motor vehicle associated therewith A drive device for a hybrid-driven motor vehicle includes a primary drive, a secondary drive, and a variable speed gearbox. The primary and secondary drives are configured to drive the gearbox separately or jointly. The gearbox includes a first input shaft connectable to the primary drive, a second input shaft connectable to the secondary drive, an output shaft, and switching elements. In a first state of the gearbox, a rotational movement of a first fixed toothed wheel of a first intermediate shaft is synchronously coupled with a rotational movement of the output shaft by a first switching element. In a second state, a rotational movement of a first idler toothed wheel on the first input shaft is synchronously coupled with a rotational movement of a second idler toothed wheel on the first input shaft by a second switching element.
US11059364B2	Drive device for a vehicle axle of a two-track vehicle A drive device for a vehicle axle, especially a rear axle, of a two-track vehicle, wherein the vehicle axle comprises an axle differential, which can be connected at the primary end to a primary drive machine and can be connected at the output end across flange shafts arranged on either side to vehicle wheels of the vehicle axle, wherein the vehicle axle is associated with an additional drive machine and a shiftable superimposing gear, which can be shifted to a torque distribution gear in which a drive torque is generated by the additional drive machine, depending on the magnitude and direction of rotation of which a torque distribution on the two vehicle wheels can be changed, and shifted to a hybrid mode in which the drive torque generated by the additional drive machine can be coupled to both flange shafts of the vehicle wheels, evenly distributed across the axle differential.
US11059356B2	Rear door of bodies of lorries or lorry trailers A rear door of bodies of lorries or lorry trailers, with at least one door leaf, which is hinged on the body to pivot about at least one vertical door axis provided in the corner region of the body. In order to mount accessories, advertising surfaces or lateral air deflectors, preferably in the region of the main closing edge of the door leaf, a supporting frame is hinged to pivot about a vertical frame axis, which supporting frame extends horizontally and substantially as far as the outer wall. In this lateral region, the supporting frame has a projection along at least part of its height, which projection engages in a groove-like recess congruent thereto on the body or on a component connected thereto, when the rear door is closed ready for travel.
US11059351B2	System and method for heating passenger cabin with combination of power electronics and electric machine waste heat A vehicle includes an oil-cooling system arranged to circulate oil through an electric machine and an oil-to-coolant heat exchanger. A coolant system has conduit arranged to circulate coolant through an inverter, a heater core, and the heat exchanger. A climate control system is arranged to circulate an airstream through the heater core to heat a passenger cabin with waste heat from the electric machine and the inverter.
US11059349B2	Enhanced climate control Data about a skin response characteristic are collected from a vehicle occupant. A target cabin temperature is determined based on the skin data. A climate control system is adjusted based on the target cabin temperature.
US11059348B2	Vehicle interior environment control A computer-implemented process for controlling a vehicle interior includes detecting a previously defined situation that relates to an undesirable environmental condition of the vehicle interior, and assessing both a risk level and an urgency level, based on a vehicle sensor input. The process also includes generating a vehicle command based upon the detected previously defined situation, the assessed risk level, and assessed urgency level, and executing the generated vehicle command to control at least one of an engine, a window, and a heating, ventilation and air conditioning (HVAC) unit to modify an environmental condition of the vehicle interior.
US11059346B2	Air conditioner An air conditioner for air conditioning a vehicle interior of a motor vehicle, comprising a coolant connection, a refrigerant connection, a condensed water connection, and an air supply channel connection which are each arranged in a front coupling plate and are surrounded by a circumferential seal.
US11059344B2	Stabilizer for vehicle, and shot peening jig for stabilizer A stabilizer includes bend sections. With respect to positions in a circumferential direction of a radial cross section of each of the bend sections, a center of an inside of a bend is defined as 0°, and a center of an outside of the bend is defined as 180°. The bend sections each include a bend interior section located at 0°, a bend exterior section located at 180°, a first side section located at 90°, and a second side section located at 270°. The bend interior section has compressive residual stress from a surface to a first depth. The bend exterior section has compressive residual stress to a second depth. The first side section has compressive residual stress to a third depth. The second side section has compressive residual stress to a fourth depth.
US11059336B1	Retractable hitch adaptor system A movable assembly is formed of a reciprocable sub-assembly and a pivotable sub-assembly. The reciprocable sub-assembly has a tubular housing. The tubular housing is reciprocable within a receiver. The reciprocable sub-assembly has a block reciprocable within the housing. The pivotable sub-assembly has a trailer hitch ball and a pivot sleeve. A neck fixedly couples the trailer hitch ball and the pivot sleeve.
US11059335B2	Tire traction devices A tire traction assembly for mounting upon a tire. The assembly includes a plurality of flexible members such as chains or cables engaged in pivoting connections with brackets at opposing ends. A separable adjustable connector such as a toothed member is attached to a first of the two brackets and configured for engagement with a ratchet mechanism attached to the second of the brackets to releasably secure the tire traction assembly around the tire. A plurality of traction cables configured to traverse the rolling surface of the tire are located in-between the brackets. The brackets may include a planar tread plate which has opposing planar side surfaces configuring the brackets to a U-shape.
US11059334B2	Tyre dismounting apparatus adapted to be installed on a motor vehicle and tyre dismounting method A tyre dismounting apparatus adapted to be installed on a motor vehicle comprises: a base configured to be fixed to the motor vehicle; a frame, hinged to the base and tiltable about a tilting axis between a rest position and a working position; a tilting actuator connected to the base and to the frame to move the frame relative to the base; a wheel-holder unit configured to receive a wheel and lock it in place and rotating about an axis of rotation to drive the wheel in rotation about the axis of rotation; a longitudinal actuator connected to the frame and configured to move the wheel-holder unit along a longitudinal axis having at least one component in a vertical direction, parallel to the direction of the weight force; a working unit connected to the frame and including a rod and a tool connected to the rod. The tyre dismounting apparatus comprises a transverse actuator connected to the working unit to move it translationally relative to the wheel-holder unit along a transverse axis parallel to the tilting axis of the frame.
US11059332B2	Foldable tire A foldable tire includes a tire main body provided at two edges thereof with two tire beads respectively. A plurality of rings are disposed in each of the tire beads. Each of the rings has a reinforcing core, which includes a plurality of flexible steel filaments helically entwined with each other and has a diameter ranging from 0.2 millimeters to 0.5 millimeters, and a cladding layer clothing the reinforcing core, so that the reinforcing cores located in each of the tire beads are separated from each other.
US11059327B2	Pneumatic tire A pneumatic tire is equipped with: a first circumferential groove and a second circumferential groove which are formed on a tread surface of a tread portion and extend along a tire circumferential direction while being arranged side by side in a tire width direction interposing an equatorial plane of the tire therebetween; a plurality of first auxiliary grooves which are arranged in the tire circumferential direction, disposed intersecting the tire circumferential direction, and communicate with the second circumferential groove by passing through the first circumferential groove, and a plurality of second auxiliary grooves which are arranged in the tire circumferential direction, disposed intersecting the tire circumferential direction so as to incline in the tire width direction, communicate with the second circumferential groove, and bend continuously with respect to the first auxiliary groove bounded at the second circumferential groove.
US11059322B2	Wheel for railway vehicle The wheel is for a railway vehicle that travels on a rail. The wheel includes a wheel tread, a flange and a throat portion. The wheel tread is provided at an outer circumferential portion of the wheel. The wheel tread faces a head surface of the rail. The flange is provided at the outer circumferential portion of the wheel. The flange projects further outward than the wheel tread in the radial direction of the wheel. The throat portion connects the surface of the flange and the wheel tread. The throat portion has a protrusion. The protrusion projects to the rail side. The protrusion extends along the entire circumference of the throat portion.
US11059319B2	Security devices and methods of manufacturing image patterns for security devices A method of manufacturing an image pattern for a security device includes providing a metallised substrate; applying a first photosensitive resist layer to a substrate first metal layer exposing the resist layer to radiation; exposing the resist layer to a first reactant substance; activating a cross linking agent in the resist layer; exposing first and second pattern elements of the resist layer to radiation of a wavelength to which the resist layer is responsive whereupon newly-exposed first pattern elements of the first photosensitive resist layer react, resulting in increased solubility by the second etchant substance, the second pattern elements remaining relatively insoluble by the second etchant substance; and applying first and second etchant substances to the substrate whereupon the first pattern elements of both the first resist layer and the first metal layer are dissolved, the remaining second pattern elements of the first metal layer forming an image pattern.
US11059318B2	Optical device, display body, device provided with a display body, optical filter, and method for manufacturing an optical device An optical device comprises a support having a reference plane, and a dielectric periodic structure including a plurality of periodic elements which are arranged, on the reference plane, in a two-dimensional lattice having a sub-wavelength spacing and are either projections projecting from the reference plane or recesses depressed from the reference plane. The optical device further includes a metal layer, which is positioned on a surface of the periodic structure including a region of the reference plane surrounding the individual periodic elements and the surfaces of the periodic elements and which has a shape that follows the surface profile of the periodic structure.
US11059307B2	Printing apparatus and moving method for support portion Provided is a printing apparatus including a support portion supporting a medium, a movement unit configured to move the support portion in a movement direction, a printing unit configured to perform printing on the medium when the support portion is in a printing region, and a control unit configured to control movement of the support portion. The movement unit includes a belt movement mechanism configured to move the support portion by rotating an endless belt, and a linear movement mechanism configured to move the support portion with a linear motor. The control unit moves the support portion with the linear movement mechanism when the support portion moves in the first range with the printing unit performing printing on the medium and moves the support portion with the belt movement mechanism when the support portion moves within the second range.
US11059304B2	Photo-curable ink jet ink set and ink jet recording method using the same A photo-curable ink jet ink set includes an undercoating photo-curable ink jet ink containing a (meth)acrylic acid ester having a vinyl ether group expressed by general formula (I), and an overcoating photo-curable ink jet ink. The undercoating photo-curable ink jet ink has a higher surface tension than the overcoating photo-curable ink jet ink.
US11059302B2	Thermal printer A thermal printer comprises a base part, a holding member, a printing device and a platen roller. When an uneven pressing force is applied to the printing device by the recording paper sheet, the printing device is capable of swinging about the support pin serving as a fulcrum in order to even out the pressing force. The deformable mechanism is capable of being plastically deformed to keep the position of the printing device. An elastic element is disposed between the holding member and the base part, and due to the elastic element, both the printing device and the platen roller are in close contact with the recording paper sheet when the recording paper sheet is clamped between the printing device and the platen roller. The printing force of the printing device acting on the printing paper sheet can be distributed more even to achieve clearer printing.
US11059301B2	Inkjet printing apparatus and method of controlling inkjet printing apparatus An inkjet printing apparatus is provided with a tank that stores ink, a print head that performs print operation by ejecting ink supplied from the tank, a circulation unit that establishes a circulating state to circulate ink in a circulation path if print operation is performed and establishes a stopped state to stop circulation of ink if print operation is terminated, and a deaeration unit that performs deaeration operation to deaerate ink inside the circulation path. The apparatus includes an estimation unit that estimates a dissolved gas amount in ink inside the circulation path based on dissolved gas amounts increased in the circulating state and in the stopped state, respectively, and a control unit that causes the deaeration unit to execute deaeration operation after completion of print operation if the dissolved gas amount estimated by the estimation unit exceeds a predetermined threshold.
US11059290B2	Fluid ejection device A fluid ejection device includes a fluid slot, three laterally adjacent fluid ejection chambers each having a drop ejecting element therein, a fluid circulation path communicated with each of the three laterally adjacent fluid ejection chambers, and a fluid circulating element within the fluid circulation path, with at least two laterally adjacent fluid ejection chambers of the three laterally adjacent fluid ejection chambers to substantially simultaneously eject drops of fluid therefrom such that the drops of fluid are to coalesce during flight.
US11059288B2	Drive circuit for liquid ejecting device and liquid ejecting device A drive circuit of a liquid ejecting device includes a first switch, a second switch, and a signal processing circuit. The first switch is connected between a first potential and an output terminal through which a drive signal is transmitted to an actuator of a liquid ejecting device. The second switch is connected between the output terminal and a second potential lower than the first potential. The signal processing circuit is configured to detect a difference between a waveform of a target drive signal and the drive signal waveform output at the output terminal, and to cause the first switch and the second switch to be off when an absolute value of the difference is less than a threshold value.
US11059287B2	Liquid discharge apparatus A liquid discharge apparatus includes an actuator and a drive circuit. The actuator is configured to cause liquid to be discharged from a nozzle. The drive circuit is configured to apply a waveform to the actuator during a discharge cycle in accordance with a discharge trigger and to cause a voltage of the actuator to be maintained at a value from an end of the discharge cycle until reception of a subsequent discharge trigger.
US11059284B2	Sleeve for a bridge mandrel, and a bridge mandrel and sleeve assembly A substantially tubular interchangeable sleeve is adapted for applying a printing or coating liquid to a substrate material or offset roller. The sleeve has a multi-layer construction primarily consisting of a first outer layer of a dimensionally stable substantially fluid-impregnable solid material, such as aluminum or steel, around the exterior surface of which is affixed or applied a print or coating liquid receiving plate or layer. The sleeve further comprises one or more further interior layers of relatively less dimensionally stable, compressible, usually fibrous materials disposed inwardly of the interior surface of the first layer which, under air pressure, can be compressed so as to enlarge the inner dimensions of the sleeve so that it can be slid over a suitable bridge mandrel. The sleeve further comprises at least one end ring of a dimensionally stable substantially fluid-impregnable solid material.
US11059283B2	Screen printing device Provided is a screen printing device. A screen printing device according to an embodiment of the present invention includes: a screen disposed adjacent to an upper portion of a substrate on which a printing process is performed, and having a pattern to be printed on the substrate; a printing unit disposed on an upper portion of the screen and configured to discharge ink supplied from the outside to the screen and to print the pattern on the substrate; a driver connected to at least one of the screen and the printing unit and configured to drive at least one of the screen and the printing unit; and a controller connected to the printing unit and the driver and configured to control operations of the printing unit and the driver, wherein, when at least one of the screen and the printing device moves in a state in which the printing unit contacts the screen, the controller controls the printing device to perform printing on the substrate by using discharge pressure of the ink.
US11059280B2	Device and method for bonding substrates A method for bonding a contact surface of a first substrate to a contact surface of a second substrate comprising of the steps of: positioning the first substrate on a first receiving surface of a first receiving apparatus and positioning the second substrate on a second receiving surface of a second receiving apparatus; establishing contact of the contact surfaces at a bond initiation site; and bonding the first substrate to the second substrate along a bonding wave which is travelling from the bond initiation site to the side edges of the substrates, wherein the first substrate and/or the second substrate is/are deformed for alignment of the contact surfaces.
US11059279B2	Adhesive tape applicator Provided herein are applicators and methods for dispensing adhesive tape. Such adhesive tape applicators include a housing adapted to contain a roll of adhesive tape; a compressible tape hub attached to an inner surface of the housing and adapted to rotatably support the roll of adhesive tape; and an adhesive roller apparatus for applying the adhesive tape to a substrate. The compressibility of the compressible tape hub provides a means of braking and tearing the adhesive tape roll.
US11059276B2	Release film for gravure application The present invention relates to biaxially oriented polyester films having a release coating of polyolefin wax on at least one side as release film for applying thin polyacrylate layers from organic solvents by means of a printing process. The invention further relates to a method for producing such films and also to their use.
US11059272B2	Polarizing plate assembly There is provided a polarizing plate, including: a polarizing layer having a thickness not greater than 20 μm; a first protective film stacked on one surface of the polarizing layer, with a first adhesive layer formed from an active energy ray curing adhesive being interposed; and a second protective film stacked on the other surface of the polarizing layer, with a second adhesive layer formed from a water-soluble adhesive being interposed. There are also provided a polarizing plate with a pressure sensitive adhesive layer, a substrate having a polarizing plate bonded thereto, a liquid crystal display device, and an organic electroluminescence display device, all of which include the polarizing plate. Preferably, at least one of the first protective film and the second protective film has a moisture permeability not higher than 1000 g/m2/24 hr.
US11059271B2	Component composed at least to some extent of a layer structure and process for production thereof The invention relates to a component having at least to some extent a layer structure, wherein the layer structure includes an elastomer layer with a density greater than 800 g/L, and a thermoset layer including at least 50% by weight of a first polyurethane. The invention further relates to a process for the production of a component of this type, the process including (i) provision of a female mold into which the individual layers of the layer structure are introduced, or of a male mold to which the individual layers of the layer structure are applied; (ii) production of the elastomer layer via spraying; (iii) production of the thermoset layer via spraying; and (iv) demolding of the resultant component. Step (ii) can be carried out before step (iii) or step (iii) can be carried out before step (ii).
US11059267B2	Metal and graphite laminate The present invention is a laminate sheet having two laminae. The first lamina is a relatively hard material having first and second surfaces. The first surface has a plurality of raised and generally pointed piercing structures, each structure having a tip. The second lamina is graphite foil material, which is mated to the relatively hard material, such that at least some of the piercing structures pierce the graphite foil material. In one embodiment, the first lamina has no performations and is uniformly smooth. In another embodiment, the second surface also has a plurality of piercing structures and a third lamina comprising graphite foil is mated to the second surface.
US11059262B2	Method of preparing low-dust and high-insulation aerogel blanket The present invention relates to a method of preparing an aerogel blanket in which, a surface of a base material for a blanket is activated and roughness and porosity of the surface of the base material for a blanket are increased to increase adhesion performance of a silica aerogel by inducing etching of a surface of a base material for a blanket using an acidic solution, and mechanical flexibility is increased and the generation of dust is minimized by further performing a gel deformation process of introducing cracks into the aerogel, and a low-dust and high-insulation aerogel blanket prepared according to the present invention.
US11059260B2	Prepreg, metal-clad laminated board, and printed wiring board A prepreg including: a woven cloth substrate; and a semi-cured product of a resin composition. The resin composition contains: at least one of an (A1) component and an (A2) component, a (B) component; a (C1) component; and a (C2) component. The (A1) component is an epoxy resin having at least one of a naphthalene skeleton and a biphenyl skeleton. The (A2) component is a phenol resin having at least one of a naphthalene skeleton and a biphenyl skeleton. The (B) component is a high molecular weight polymer. The (C1) component is a first filler obtained by treating surfaces of a first inorganic filler with a first silane coupling agent represented by formula (c1). The (C2) component is a second filler obtained by treating surfaces of a second inorganic filler with a second silane coupling agent represented by formula (c2).
US11059259B2	Composite core with reinforced plastic strips and method thereof Some embodiments provide a core member for a composite panel that includes a hollow cell network structure, such as a honeycomb arrangement for example, and reinforced plastic strips positioned on a portion of the continuous honeycomb structure. The honeycomb structure and the solid plastic strips may be fastened together using heat and/or pressure applications. Additionally, the method for the production of the core member is provided.
US11059258B2	Multilayer combining both good ageing properties and resistance to bursting in hot conditions, that can be used for high-temperature motor vehicle applications The present invention concerns a multilayer tubular structure (MLT) intended for transporting fluids such as air, oil, water, a urea solution, a cooling liquid made from glycol, a transmission oil cooler (TOC), or an air conditioning liquid, or a fuel such as petrol, in particular bio-petrol, or diesel, in particular bio-diesel, comprising at least one layer (1) and at least one layer (2), said layer (1) comprising a composition comprising: -a) at least 50% by weight of at least one semi-aromatic polyamide of formula W/ZT, -b) at least 10% by weight, preferably at least 15%, of an impact modifier, -c) between 0 and 20% by weight of at least once plasticiser, -d) between 0 and 40% by weight of at least one additive, the sum of a) +b) +c) +d) being equal to 100%, said layer (2) comprising a composition comprising a′) at least 50% by weight of at least one short-chain semi-crystalline polyamide referred to as (A), said short-chain aliphatic polyamide (A) being of formula X Y/Z, or formula V/Z, -b′) between 0 and 15% of at least one impact modifier, -c′) between 0 and 12% by weight of at least once plasticiser, -d′) between 0 and 40% by weight of at least one additive, the sum a′)+b′)+c′)+d′) being equal to 100%.
US11059256B2	Apparatus and method for expanding a slit sheet material to form an expanded packaging product An apparatus (10) for converting a slit-sheet stock material (16) into an expanded dunnage product (12) includes a housing (20), a pair of rollers (22, 24) within the housing extending widthwise across a path of the sheet material, and a plurality of guide strips (90) extending from an upstream side of the pair of rollers to a downstream side of the pair of rollers at a plurality of locations spaced across the width of the path. The guide strips guide the sheet material between and around the rollers. Exemplary rollers have a plurality of grooves spaced across the width of the path, and the guide strips are received in respective grooves. The guide strips may be connected by a crossbar to form a guide member.
US11059255B2	Method and system for forming packages A system and method of at least partially forming reinforced packages. The method comprises moving a web of material in a downstream direction through a web forming section, at least partially forming at least a bag portion in the web of material during the moving the web of material through the web forming section, forming an attached web by adhering a construct to the bag portion of the web of material, and moving the attached web through a separating station. The moving the attached web can comprise moving the construct with the web of material. The method further can comprise separating the bag portion from a remainder of the web of material to form a bag during the moving the attached web through the separating station, the bag being attached to the construct.
US11059253B2	Method and system for cardboard pretreatment A system and methods for operating a cardboard processing machine, the method comprising creating a pre-processing crease at a location on the cardboard where it is required to process the cardboard; and processing the cardboard along the pre-process crease.
US11059251B2	Press system and control method for press system A press system includes a detection unit configured to detect occurrence of an abnormality during press working for a workpiece, and an abnormality determination unit configured to determine an abnormality level, based on the abnormality detected by the detection unit and a stoppage period for which a pressing operation is stopped after occurrence of the abnormality.
US11059248B2	Expandable rim for tire tread buffing apparatus and method A machine for retreading tires includes a rotatable hub that includes a moveable conical element, and an expandable rim disposed around the rotatable hub. The expandable rim includes a plurality of shoes. Each shoe of the plurality of shoes may have a base portion and a rim portion. The base portion may have a two-piece construction that allows for replacement of a worn interface that may include a channel and a ramp. A method for assembling an expandable rim for use in a tire retreading machine, and a method for servicing a machine having an expandable rim are also disclosed.
US11059243B2	Production device and production method for pultrusion molded article This device for producing a pultrusion molded article is provided with: a mold member that heats and cures an intermediate molded article as a result of the mold member contacting an intermediate molded article in which reinforcing fibers are impregnated with a thermosetting resin; a pultrusion device for extracting, in the pultruding direction, the pultrusion molded article formed by heating and curing the intermediate molded article; and a moving device for moving the mold member in the pultruding direction in synchronization with the pultrusion device.
US11059239B2	Method and apparatus for composite rib and rib-and-sheet molding Rib-and-sheet structures include a rib comprising continuous, aligned fibers. The rib is fabricated via compression molding from continuous, aligned fiber, thereby providing an aligned, continuously reinforced rib. In one embodiment, rib-and-sheet structures are produced in a two-step compression-molding process, wherein a near net-shape rib is molded, in a first mold, from fiber-bundle based preforms, and then a rib-and-sheet part is molded by placing, in a second mold, the rib with either: (i) a preformed sheet, (ii) plies that form a laminate/sheet or (iii) chopped fibers that form a sheet during the molding process. In another embodiment, rib-and-sheet structures are fabricated in a one-step compression-molding process, wherein fiber-bundle-based preforms and (i) a preformed sheet, (ii) plies that form a laminate/sheet, or (iii) chopped fibers are combined in a single mold and molded in a single step.
US11059234B2	Compositions for capstock applications A thermoplastic polymer alloy compositions including a blend of polymers that each contribute beneficial properties to the compositions. The compositions exhibit characteristics desirable for outdoor applications such as weatherability, impact resistance and durability, while offering excellent surface appearance. The compositions are particularly suitable for decking applications and as capstock materials.
US11059233B2	Laser welding system and method using cooling mask to control the width of the weld A laser welding method and system for joining portions of first and second workpieces of thermoplastic material that is partially permeable to a laser beam but absorbs radiation from the laser beam. The first and second workpieces, which are made of material that absorbs radiation from a laser beam, are clamped together. A mask is placed on a first surface of the first workpiece, the first surface being opposite the surface engaging the second workpiece. The mask is impermeable to a laser beam and forms a slot for passing a laser beam to the portion of the first surface of the upper workpiece exposed by the slot, so that heating and melting of the material of the workpieces is limited to the width of the slot. A laser beam is directed onto the slot and moved in a manner to illuminate the slot to melt and join the workpieces.
US11059232B2	Portable table top welder A portable table top welder for welding plastic material webs, the portable table top welder including a frame including a carrier housing and a support arm at which a welding device is arranged; at least one transport roller including a rotatable transport roller axle and at least one contact pressure roller that is rotatably supported at the carrier housing, wherein a weight is arranged at an eccentrical element which is rotatably connected at one side by a concentrically supported eccentrical element axle at the carrier housing and rotatably connected at another side by an eccentrically supported contact pressure roller axle at the contact pressure roller. The table top welder handles and transports easily and can be mounted on a table or on another carrier structure in a disengageable manner.
US11059229B2	Rules for printing three-dimensional parts In some examples, a request to print a first three-dimensional (3D) part is received. In response to determining that the first 3D part is not similar to any 3D part referred to by an information base, a representation of the first 3D part is extracted, an indication to conduct an operation to produce a design rule for the first 3D part is sent. In response to determining that the first 3D part is similar to a matching 3D part referred to by the information base, a design rule for the matching 3D part is retrieved to print the first 3D part, where the design rule for the matching 3D part specifies a dependency of a property of the matching 3D part on an aspect associated with printing the matching 3D part.
US11059228B2	Systems and methods for printing of 3D models There is provided a method of representing a three dimensional (3D) object using univariate curves, comprising: receiving an initial definition of a 3D object representation, calculate a covering set of univariate curves, the covering set comprising at least one non-planar univariate curve, wherein the covering set of univariate curves represent the volume of the 3D object within a tolerance requirement, and generating a representation of the 3D object based on the set of univariate curves, wherein the set of univariate curves represent the volume of the 3D object.
US11059227B2	Print head for additive manufacturing An additive manufacturing system may include a carrier, a set of rails coupled to the carrier, and a transition housing movably attached to the set of rails. The additive manufacturing system may include an extruder having an extruder barrel coupled to the transition housing, and a melt pump fixedly attached to the carrier. The melt pump may be in fluid communication with the extruder barrel. Additionally, the additive manufacturing system may include a nozzle in fluid communication with the melt pump, and a roller rotatable about the nozzle.
US11059222B2	Continuous digital production of 3D articles of manufacture A three dimensional (3D) printer enables the continuous manufacture of 3D articles of manufacture. The 3D printer includes a 3D print engine for generating articles of manufacture through a layer by layer solidification of a print medium, a transport mechanism, a receiving station, and a controller. The controller is configured to (a) operate the 3D print engine to generate a continuous build platform, (b) concurrently with (a), operate the print engine to generate a plurality of 3D articles of manufacture that are attached to the continuous build platform; and operate the transport mechanism to engage the continuous build platform to transport the continuous build platform along a path that extends between the 3D print engine and the receiving station.
US11059217B2	Method and apparatus for transposing extruded materials to fabricate an object surface In the formation of a solid object by progressively adding extruded materials to a workpiece, a mechanism is disclosed for transposing the paths by which two or more extrusion nozzles travel to deposit materials. Paralleling a surface contour of the object being formed, the paths for two or more substantially continuous extruded traces are directed in complementary fashion to cause a first extrusion trace to form the object surface while a second extrusion trace is deposited behind the first trace. At another position along the surface contour, the paths of the extruded traces may cross over one another to allow the second extruded trace to define the object surface. Where the first and second traces have a different color or visual appearance, the disclosed mechanism enables fine graphic features to efficiently be integrated into the surface of the object being formed.
US11059211B2	Injection molding control method The present invention discloses an injection molding control method. The injection molding control method comprises the following steps: establishing a work command according to a plurality of production process parameters; receiving a position information directly from an injection molding machine; and controlling a servo pump to drive the injection molding machine according to the position information and the work command.
US11059210B2	Plastic injection molding machine and molding method A plastic injection molding machine and molding method related to an injection molding machine for stack molds, wherein the central portion of the mold remains fixed and it has two molding faces that act on the fixed central portion by means of a hydraulic chamber that produces the clamping force and prevents the deformations due to bending on the molding faces. Likewise, it relates to a molding method.
US11059202B2	Method and device for producing planar modifications in solid bodies A method for creating modifications in a solid-state material is described, wherein a crack guidance region for guiding a crack for separating a solid-state layer from the solid-state material is predetermined by the modifications. The method includes: moving the solid-state material relative to a laser processing system; successively emitting a plurality of laser beams from the laser processing system to the solid-state material to create at least one modification within the solid-state material; and continuously adjusting the laser processing system for defined focusing of the plurality of laser beams and/or for adjustment of energy of the plurality of laser beams as a function of at least one parameter.
US11059199B2	Raw material supply device and sheet manufacturing apparatus A raw material supply device includes a housing that stores an aggregate of small pieces, a discharge port through which the small pieces are discharged from an inside of the housing, a rotor provided in the housing and including a protruding portion, and a magnet provided on the discharge port or on a downstream side of the discharge port. In addition, it is preferable that the raw material supply device further include a passage route that communicates with the discharge port and through which the small pieces pass, in which at least one pair of the magnets is disposed on one side and the other side via the passage route.
US11059197B2	Method of slicing a food item and slicing mechanism employing a gripping element that generates a vacuum grip A method of processing a food item that includes moving a food item along a direction towards an automated slicer, wherein prior to the food item being sliced by the automated slicer the food item that is being moved has a length, L, as measured along the direction. The method further includes determining a thickness, T, of a slice of the food item to be generated by the automated slicer and slicing the food item that has the length, L, by the automated slicer so that a maximum possible number, Nmax, of slices of the food item are generated that have the thickness, T.
US11059195B2	Razor blade with a printed objected A method of making a razor cartridge including providing at least one razor blade having a cutting edge extending along a length of the razor blade and printing at least one printed object on the length is provided. The razor blade is positioned between the guard and the cap where the visible surface of the at least one razor blade includes a printed object. The printed object may extend continuously along the length of the razor blade and/or may have multiple portions having a comb-like structure. The printed object appears as a solid object to a viewer's naked eye. The solid object includes a plurality of printed ink dots not visible to the viewer's naked eye. The printed object of flexible, polymer ink may act as a guard element on the razor blade which helps with glide and to manage a user's skin (e.g., bulge) during shaving.
US11059192B1	Cutting device with additional elements A food cutter apparatus with a blade portion and a handle portion. The blade portion is comprised of a single rigid material. The handle portion can be comprised of the same rigid material as the blade portion or a separate rigid material. The handle portion of the food cutter apparatus is located on top of the blade portion. In one example, a grater, slicer, or other kitchen tool elements are provided integral to the blade portion. In other examples, kitchen tool elements are provided as removable elements that can be attached to a cavity in the blade portion.
US11059187B2	Apparatus, system and method for providing a vacuum ejector for an end effector An apparatus, system and method for providing a vacuum ejector for use with an end effector. Included may be at least an end effector and a vacuum chamber for gripping an element during semiconductor processing. The end effector may include at least two clamp arms for placing a gripped element in relation to application of a vacuum to the gripped element; a vacuum cup having a mouth capable of sealing to the gripped element to provide a vacuum chamber; a vacuum ejector pin extending into the vacuum chamber and including a plurality of ports substantially at a tip thereof proximate to the gripped element, wherein the vacuum is applied by the plurality of ports; and an ejector pin actuator that is capable of moving the vacuum ejector pin toward the gripped element until the sealing of the mouth is broken and the gripped element is ejected from the vacuum cup.
US11059185B2	Apparatus and method for transferring a pattern from a universal surface to an ultimate package An apparatus and method for transferring a pattern from a universal surface to an ultimate package. The apparatus comprises an end effector for a pattern transfer robot. The end effector comprises a crowder plate with crowder plate slats spaced apart a distance to form openings between the crowder plate slats. The universal surface comprises a finger wall with finger wall slats spaced apart a distance to form openings between the finger wall slats. A portion of the crowder plate slats are sized to pass between a portion of mating finger wall slats.
US11059184B2	Gripper device and a method for picking up and re-positioning an item carried by a support surface This invention relates to a pick and place gripper device and a method for picking up and re-positioning an item carried by a support surface. The gripper device includes a base, at least one jaw pivotally mounted to the base having at least one leading edge, at least one belt of flexible material being wrapped around at least the leading edge of the at least one jaw such that it is sandwiched between the at least one jaw and the item when the at least one jaw penetrates below the item and as the at least one jaw moves below the item there is substantially no relative sliding movement between the sandwiched portion of the at least one belt and the item, wherein the leading edge of the at least one jaw, when coming into contact with the support surface, is configured to adjust to the support surface when penetrating between the item and the support surface.
US11059183B2	Apparatus, system and method for providing an end effector The disclosure provides an apparatus, system and method for providing an end effector. The end effector may be capable of accommodating semiconductor wafers of varying sizes, and may include: a wafer support; a bearing arm capable of interfacing with at least one robotic element, and at least partially bearing the wafer support at one end thereof; a plurality of support pads on the wafer support for physically interfacing with a one of the semiconductor wafers; and a low friction moving clamp driven bi-directionally along a plane at least partially provided by the bearing arm, wherein the low friction moving clamp retractably applies force to a proximal edge of the semiconductor wafer.
US11059180B2	Control device and machine learning device A machine learning device includes: a state observation unit that observes component arrangement data representing an arrangement of components on a component serving place, component data representing information of the components, and operator status data representing status information of an operator, as state variables representing a current state of an environment; a determination data acquisition unit that acquires product quality determination data for determining quality of the product which is assembled based on an arrangement of the components and takt time determination data for determining takt time for assembly of the product as determination data; and a learning unit that performs learning based on the state variables and the determination data in a manner to associate information of the components used for assembling the product and status information of the operator with respect to an arrangement of the components on the component serving place.
US11059176B2	Method and system for facility monitoring and reporting to improve safety using robots A system for facility monitoring and reporting to improve safety using one or more robots includes: a network; a plurality of autonomous mobile robots operating in a facility, the robots configured to monitor facility operation, the robots further configured to detect a predetermined critical condition, the robots operably connected to the network; a server operably connected to the robots over the network; and an individual robot operably connected to the server over the network, the individual robot operating in the facility, the robots not comprising the individual robot, the individual robot configured to monitor facility operation; wherein the robots are configured to regularly produce a regular report under normal operating conditions, the report displaying data received from the server, wherein the robots are further configured to produce to the server a critical condition report upon occurrence of the critical condition.
US11059172B2	Control apparatus and robot system A control apparatus includes a processor that is configured to execute computer-executable instructions so as to control a robot supporting a dispenser, wherein the processor is configured to calculate a movement velocity of a landing point where a discharge substance discharged from a discharge port of the dispenser to an object lands on the object, wherein the movement velocity is used for controlling a discharge amount of the discharge substance.
US11059171B2	Method and apparatus for optimizing a target working line A method and an apparatus for optimizing a target working line are disclosed. The target working line includes at least one robot manipulator, at least one conveyor and at least one item on the conveyor to be displaced by the robot manipulator. The method includes: obtaining an evaluation model for the target working line, the evaluation model yielding an overall success rate of moving the item from one conveyor to another conveyor based on at least one measuring parameter, the measuring parameter being a physical attribute of the target working line; yielding the overall success rate for the target working line as a function of a value for the measuring parameter for the target working line; and in case that the yielded overall success rate is lower than a predetermined threshold rate, updating a value for a configuring parameter based on the overall success rate, the configuring parameter corresponding to the measuring parameter, and the configuring parameter being states of the working line. The optimization of the evaluation model does not require an implementation of an on-site process or an involvement of an experienced engineer or worker. Instead, simulation software can be used to obtain customized parameters used for the target working line, resulting in an increased success rate within a short period of time.
US11059167B2	Multi-joint robot arm A multi-joint robot arm including a pair of support sections separated by a specified gap in a width direction; a first arm rotatably supported by a first joint on the pair of support sections and formed from a pair of first side plate members with a level difference such that a gap between the first joint and an end section on an opposite side becomes narrower towards the width direction side; a second arm arranged inside of the pair of first side plate members, rotatably supported by a second joint on the first side plate members, and provided with a level difference such that a gap between the second joint and an end section on the opposite side gets wider towards the width direction side; and a robot hand attached to the second arm on an end portion on the opposite side to the second joint.
US11059165B2	Method and system for assisted object handling in dangerous environments A system for remote object handling including a vehicle having a front portion. An articulated arm has a first end and a second end distinct from the first end, the arm being coupled to the front portion at the first end, and has at least one pivot disposed between the first end and the second end. A gripping element is removably coupled to the second end, wherein the gripping element is one of a pincer device, a hand device having at least three fingers or a shovel. A video camera is also coupled to the second end. An arm control is disposed within the vehicle and is operable to control the operation of the arm, the manipulator and the video camera, and a video interface is coupled to the video camera which is operable to display output from the video camera.
US11059163B2	Reversible wrench rack A wrench rack includes a base portion having a first side and a second side, and a first rail and a second rail. Each of the first rail and second rail includes a plurality of wrench slots formed at a predetermined angle. The first rail and second rail are releasably coupled with the first side and second side of the base portion, respectively, in a first configuration and the first rail and second rail are releasably coupled to the second side and first side of the base portion, respectively, in a second configuration, such that an orientation of the predetermined angle of the wrench slots of the first configuration is reversed in the second configuration.
US11059160B2	Multispeed power tool A tool with a transmission assembly having a reduction gearset and a speed selector. The speed selector has a member, an actuator and a shifter assembly. The member is movable between a first position, in which the member is non-rotatable, and a second position in which the member is coupled to a planet carrier of the reduction gearset for common rotation. The actuator includes a pivoting yoke and a follower that is coupled to the yoke. The follower engages the member so as to be axially movable with the follower. The shifter assembly has a selector switch, a switch fork, and a pair of springs. The selector switch is slidable between a first switch position and a second switch position. The switch fork is slidably coupled to the selector switch and receives the yoke. The springs cooperate to bias the switch fork relative to the selector switch into a neutral position.
US11059159B2	Electromagnetic actuator for power tool An actuator assembly for a power tool includes an actuator with a permanent magnet. The actuator is moveable between a first position for a first mode of operation, and a second position for a second mode of operation. A first positioning member is adjacent the first position composed of a ferromagnetic material to attract the permanent magnet. A second positioning member is adjacent the second position and composed of a ferromagnetic material to attract the permanent magnet. An electromagnet may be energized to move the actuator between the first position and the second position. When the electromagnet is not energized and the actuator is in the first position, the actuator is retained in the first position. When the electromagnet is not energized and the actuator is in the second position, the actuator is retained in the second position. When the electromagnet is energized, the actuator moves between the first and second positions.
US11059157B2	Impact hand tool An impact hand tool which includes an outer sleeve; an impact rod inserted to connect to the outer sleeve; a cushion pad provided inside the outer sleeve at the vertical center axis; a handle connected to the impact rod; an inner hole slot at a second end of the outer sleeve with an inner wall and an internal thread; and a tool head installed to the outer sleeve through the inner hole slot. The tool head comprises a one-piece structure of a working rod portion and a working head, a connecting rod having an external thread for coupling with the inner hole slot, a connecting sleeve connected to the connecting rod to form an integral and stepped hollow body defining a connecting cavity to receive the working rod portion, and a rubber filler to fill a gap between the working rod portion and the inner wall of the connecting rod.
US11059154B2	Two-piece guide bushing Examples of a removal tool for a two-piece guide bushing are provided. A specific example comprises a handle, a cap coupled to the handle, the cap comprising arced slots; and a raised boss coupled to the cap, the raised boss configured to fit over the stem guide of a two-piece guide bushing. The guide bushing removal tool may be coupled to a two-piece guide bushing and the guide bushing removal tool may be configured such that rotation of the handle releases the guide bushing center of the two-piece guide bushing.
US11059150B2	Elastic self-lubricating polishing tool An elastic self-lubricating polishing tool includes an elastic grinding layer including an abrasive member and an elastic base layer affixed to the abrasive member, an absorbing layer absorbing and sustainedly releasing liquid inside of the absorbing layer, and an adhesive layer overlappedly connected with the elastic base layer of the elastic grinding layer and the absorbing layer. The elastic self-lubricating polishing tool is elastic and self-lubricating to sand and polish a surface of a workpiece.
US11059147B2	Abrasive article including a coating An abrasive article can include a substrate, abrasive particles coupled by a bond material to the substrate, and a coating overlying at least partially the exterior surface of the bond material. The coating can be a poly(p-xylylene) polymer applied via vapor deposition and may provide enhanced strength to the bond material and extended life time to the abrasive article.
US11059144B2	Polishing apparatus A polishing apparatus capable of preventing wear of rollers which are to transmit a load to a retainer ring and capable of preventing wear particles from escaping outside is disclosed. The polishing apparatus includes: a retainer ring disposed so as to surround the substrate and configured to press the polishing surface while rotating together with a head body; a rotary ring secured to the retainer ring and configured to rotate together with the retainer ring; a stationary ring disposed on the rotary ring; and a local-load exerting device configured to apply a local load to a part of the retainer ring through the rotary ring and the stationary ring. The rotary ring has rollers which are in contact with the stationary ring.
US11059143B2	Tool carrier assembly for use at a lathe and lathe having such tool carrier assembly A tool carrier assembly for use at a machine tool, which includes at least one workpiece-carrying spindle for rotatably driving a workpiece received in the workpiece-carrying spindle. The tool carrier assembly includes a first slide being movable in a first direction, a tool carrier being supported on the first slide and configured to hold a plurality of tools, a tool drive unit including a tool drive for engaging with one of the plurality of tools held by the tool carrier to rotatably drive said tool, when the tool is arranged at a tool drive position with respect to the tool drive, and a drive mechanism for driving movement of the first slide together with the tool carrier in the first direction relative to the tool drive position, when the tool drive is disengaged with the tool, to relatively move another tool of the plurality of tools into the tool drive position.
US11059140B2	Flexible debris shield for handheld drills A flexible debris shield for handheld power drills for collecting debris generated while cutting or drilling holes in a work surface. The debris shield is made from a transparent flexible material in a way that it allows the debris receptacle to fold and envelop an uneven surface or in cases where the intended workspace area's width is narrower than the diameter of the shield.
US11059136B2	Workpiece holder device A workpiece holder device for a machine tool has a holder, which has a support part and a holder part. The support part supports the holder on a support device, preferably so that the holder can rotate about an axis of rotation. The holder part is set up to hold a workpiece directly or indirectly. To avoid, or at least minimize deviations from a desired alignment of the holder part based on elastic deformation of the holder due to the weight force of the workpiece, the holder has at least one mechanical or hydraulic pretensioning device arranged on or in it. The pretensioning device can be used to pretension the material of the holder, so that the pretensioning device applies a tensile stress or a compressive stress to at least one part of the holder. This can counteract a deviation of position due to an elastic deformation of the holder.
US11059135B1	Reconfigurable machining center A reconfigurable machining center includes a base structure extending in a first direction, a movable crossmember movable in the first direction and provided with a machining head, supporting elements on the base structure to enable movement of the movable crossmember along the first direction, a first leadscrew rack, integral with the base structure and having a first helical circular toothed sector, and extending along the entire base structure parallel to the first direction, and a first screw rotatably coupled to the movable crossmember and engaging a corresponding first leadscrew rack, and having a rotation axis parallel to the first direction. The longitudinal extension of the base structure in the first direction is an integer multiple of the pitch of tooth of the leadscrew racks, and the base structure includes coupling elements adapted to couple the base structure to a following and/or preceding adjacent base structure along the first direction.
US11059131B2	Methods for laser processing a substrate stack having one or more transparent workpieces and a black matrix layer A method for laser processing a substrate stack includes forming a defect in a transparent workpiece of the substrate stack having a black matrix layer. Forming the defect includes directing a portion of a pulsed laser beam into the transparent workpiece. The pulsed laser beam includes a wavelength λ, a spot size wo, and a Rayleigh range ZR that is greater than F D ⁢ π ⁢ ⁢ w 0 , 2 λ , where FD is a dimensionless divergence factor comprising a value of 10 or greater. The pulsed laser beam directed into the transparent workpiece of the substrate stack forms a pulsed laser beam focal line disposed within the transparent workpiece, where a center of the pulsed laser beam focal line is offset from an edge of the black matrix layer by a distance that is about 20% or less of a total thickness of the substrate stack and generates an induced absorption within the transparent workpiece.
US11059130B2	Device for generating a jet of liquid The present application relates to a device for generating a jet of liquid propagating along a jet axis, said jet of liquid guiding a laser beam. The device comprises a wall element having a central opening, wherein a nozzle holder comprising a nozzle and a window element comprising the window are arranged one above the other within said central opening, said nozzle holder and said window element being spaced from each other along said jet axis, said spacing defining an acceleration chamber, wherein said connection passage and said distribution chamber are formed within said nozzle holder.
US11059128B2	Multiple beam pulsed laser deposition of composite films The present disclosure generally relates to a system and method for multiple beam laser deposition of thin films wherein separate laser beams are used to ablate material from separate targets for concurrent deposition on a common substrate. The targets may include, but not limited to polymers, organics, inorganics, nanocrystals, solutions, or mixtures of materials. A target may be disposed on a tiltable mount to adjust the direction of the ablation plumes. Multiple ablation modes may be concurrently employed at the various targets, including, but not limited to pulsed laser, MAPLE, IR-MAPLE and other modes. The system may include a camera and processor for plume axis determination and feedback control of the plume axis by controlling a tilt of a target holder. Maple target loading sequences and liquid states are described. Fluorescent image monitoring is described.
US11059122B2	Connecting plasma arc torches and related systems and methods In some aspects, contact members to connect plasma torch leads to plasma cutting systems can include: a base portion; a set of ports within the base portion that include: a coolant supply port to convey a liquid coolant from the cutting system to a plasma arc torch connected to the contact member by the torch lead, a coolant return port: i) to convey return liquid coolant from the torch to the cutting system, and ii) to convey an operational current from the cutting system to the torch, at least one gas supply port to convey processing gases to the torch, and an ohmic contact connector; and a connector to couple the base portion to the cutting system and connect each of the ports and electrical connectors to respective complementary connections of the cutting system upon coupling to the cutting system.
US11059113B2	Slitting machine A slitting machine for removing a strip from a sheet of material. The slitting machine has a blade assembly with first and second cutting blades, and a perforating blade arranged between the first and second cutting blades. The first and second cutting blades are arranged to cut the sheet of material to define the strip and the perforating blade is arranged to perforate the sheet of material to define an end of the strip.
US11059111B2	Cutting insert and indexable ball end mill A cutting insert includes a rake face, a seating face facing an opposite side to the rake face and seated on an insert mounting seat, and a flank face extending around the rake face and the seating face, in which two cutting edges each having an arcuate cutting edge portion extending in an arc shape and a linear cutting edge portion which is in contact with the arcuate cutting edge portion are formed on an intersecting ridgeline portion between the rake face and the flank face, a groove portion having a wall surface coming into contact with a projection portion protruding from a bottom surface of the insert mounting seat is formed on the seating face, and the groove portion has a narrow width portion in which a groove width decreases from one end side toward the other end side in a direction in which the groove portion extends.
US11059109B2	Cutting head having torque transmission surfaces on a mounting protuberance and rotary cutting tool having such cutting head A cutting head rotatable about a head axis, has a cap portion and a mounting protuberance joined thereto and extending axially rearwardly therefrom. The mounting protuberance has a plurality of circumferentially spaced apart torque portions axially offset from a plurality of circumferentially spaced apart clamping portions. The clamping portions have clamping surfaces circumscribed by an imaginary clamping circle with a clamping diameter. The torque portions have torque protrusions and torque cut-outs, each torque protrusion having a torque transmission surface at least partially located outside an imaginary clamping cylinder defined by the imaginary clamping circle, and each torque cut-out having a recessed surface located inside the imaginary clamping cylinder. The cutting head is releasably secured to a head receiving pocket of a tool shank, with each clamping surface contacting a corresponding abutment surface of the pocket, and each torque transmission surface contacting a corresponding drive surface of the pocket.
US11059106B2	Systems and methods for forming perforations in a barrel structure A drilling system includes a single robotic drilling unit having a drill end effector positioned inside a barrel section configured as a composite sandwich structure having an inner face sheet. The robotic drilling unit is operable to drill a plurality of perforations into the inner face sheet using the drill end effector. The robotic drilling unit is configured to index a hole pattern of the perforations to one or more cell walls of a honeycomb core of the composite sandwich structure. The robotic drilling unit is configured to form the hole pattern in the inner face sheet such that the perforations are located at a spaced distance from the cell walls of the honeycomb core.
US11059104B2	Cutting tool and method of manufacturing machined product A cutting tool may include a holder and a cutting insert. The cutting insert may include a ridge including a corner and a first side. The holder may include a first flow path extending along a first central axis, and a second flow path extending along a second central axis. A line obtained by extending the first central axis may be a first imaginary line, and a line obtained by extending the second central axis may be a second imaginary line, each of the first imaginary line and the second imaginary line is inclined downward. An intersection of the first imaginary line and the second imaginary line is located outside of the cutting insert in a plan view. The first imaginary line intersects with the ridge and the second imaginary line intersects with the first side at a side closer to the second end than the first imaginary line.
US11059103B2	Additive manufacturing A method of additive manufacturing metallic components, the method includes: forming a component in a layer by layer process, the component being formed integrally with at least one non-perforated support structure to be separated from the component after the layer by layer process, the support structure being formed with at least one wall that is non-perforated; and wherein after completion of the layer by layer process, the method includes exposing the component and support structure to at least one thermal pulse so as to weaken, or break, the interface(s) between the support structure and component prior to removal of the support.
US11059101B2	Conformal material and support structures for additive manufacturing systems and methods of use thereof Aspects of the disclosed technology include an additive manufacturing method including: applying a mixture of metal powder and a carrier agent to a substrate; removing a portion of the carrier agent from the applied mixture; and fusing the metal powder remaining in the applied mixture to the substrate.
US11059097B2	Additive manufacturing build plates and handling An additive manufacturing build plate system includes a plate body defining a build surface and a rear surface opposite the build surface. A peripheral surface extends between the rear surface and the build surface. At least one gripping feature is defined in the peripheral surface, extending inwardly into the plate body between the build surface and the rear surface.
US11059095B2	Method and apparatus for generating a molten raw material for three-dimensional printing A method and apparatus for generating a molten raw material for three-dimensional printing, in which a solid raw material is heated to obtain the molten raw material. The solid raw material is heated to a molten state by electromagnetic induction outside the output end of the guiding device to form a molten segment. The molten segment is supported by the solid raw material and is not in contact with other structures after being in contact with the printed object and/or the support platform.
US11059094B2	Method and device for preparing semi-solid slurry A method for preparing semisolid slurry. The method is achieved using a device for preparing semisolid slurry. The device includes a slurry vessel and a mechanical stirring rod. The mechanical stirring rod includes a first end and a second end extending into the slurry vessel. The method includes: S1. putting a molten alloy having a first preset temperature into the slurry vessel; S2. cooling the molten alloy to a second preset temperature, positioning the second end of the mechanical stirring rod to be 5-25 mm higher than the bottom wall of the slurry vessel, rotating the mechanical stirring rod and injecting a cooling medium into the mechanical stirring rod; and S3: allowing the temperature of the molten alloy to be 10-90 degrees centigrade lower than the liquidus temperature of the molten alloy, stopping stirring and cooling, to yield a semisolid slurry.
US11059093B2	Additively manufactured core for use in casting an internal cooling circuit of a gas turbine engine component A core for use in casting an internal cooling circuit within a gas turbine engine component includes a base core portion and an additive core portion additively manufactured to the base core portion. A method of manufacturing a core for use in casting an internal cooling circuit within a gas turbine engine component including additively manufacturing an additive core portion to a base core portion.
US11059092B2	Method for joining heat transfer plates of a plate heat exchanger A method for joining heat transfer plates, comprising: applying a melting depressant composition on individual application areas of a first metal sheet, each application area comprising a mid-section and two end-sections; pressing ridges and grooves in the metal sheet, the ridges extending in a direction that extends between the end-sections of the application areas, such that the application areas are located on top of the ridges; bringing the metal sheet into contact with a second, pressed metal sheet, such that contact points are formed where the mid-sections of the application areas relocated; heating the sheets until melted metal is formed at the application areas where the melting depressant composition is applied; and allowing the melted metal to solidify such that a joint is obtained at the contact points.
US11059090B1	Servo-driven seamer assembly for sealing a container A seamer assembly includes a frame, a first servo assembly, a second servo assembly, a first support element, a second support element, a first die, and a second die. The first servo assembly is coupled to the frame. The first servo assembly includes a chuck that is configured to be rotated by the first servo assembly. The second servo assembly is coupled to the frame. The first support element is configured to support a can subassembly that includes a can body and a lid relative to the frame where at least one of the first support element, the first servo assembly and second servo assembly move relative to the other of the first support element, the first servo assembly and second servo assembly. The second support element is coupled to the second servo assembly. The first die is coupled to the second support element. The second die is coupled to the second support element. The first support element is configured to support a can subassembly such that the chuck is received in a first chuck position. The first servo assembly is configured to selectively rotate the can subassembly when the chuck is received in the first chuck position. The second servo assembly is configured to selectively reposition the second support element such that the first die and the second die are correspondingly repositioned.
US11059087B2	Method for producing stamped parts A stamped or fine-blanked, workpiece is inserted in an embossing device, and the burr created on the workpiece during stamping or fine blanking is rounded by way of a die of the embossing device and the height of the rollover created during stamping or fine blanking is decreased using the same stroke of the embossing device by way of which the burr rounding is carried out.
US11059078B2	Underwater sensor protection device and method employed thereof Exemplary embodiments of the present disclosure are directed towards an underwater sensor protection device and method employed thereof. The underwater sensor protection device comprises a focal tube. The focal tube comprises at least one open end and at least one top closed end, the top closed end is connected to a control board and the open end is kept open, the control board comprises an air pump and a solenoid valve, the focal tube is submerged in water level for regulating the air pump. Sensors are positioned in the focal tube. Air is passed through an air tube to the focal tube and vacates the volume of water within the focal tube for avoiding water contact with the sensors, and air bubbles are generated by passing air via the air tube for longer duration into the focal tube thereby performing cleaning operation of the sensors.
US11059076B2	Sorting support methods, sorting systems, and flatbed machine tools A method for assisting a user with sorting workpieces disposed on a sorting table uses a positioning system for determining a spatial position of a user's hand. The position can be determined by a sorting assistance unit worn near a hand of the user and the position of which is detected by the positioning system, or by image-based positioning using one or more cameras. The method comprises providing a position data set that includes the positions of the workpieces produced of the machining plan on the sorting table; by the positioning system, detecting a position of the user's hand and comparing it with the positions of the position data set; identifying at least one workpiece that is paired with the position of the user's hand; and outputting a sorting signal which comprises information about the at least one workpiece paired with the position of the user's hand.
US11059072B2	Screen plate for screening plants for mechanical classification of polysilicon Polysilicon chunks or granules are classified into size fractions using a mechanical screen having a profiled surface having peaks and valleys, and terminating in widening slots through which a polysilicon size fraction falls. The device is effective and the slots are resistant to clogging.
US11059070B2	Device and method for dynamic metering of sealing compounds Described herein is an apparatus for dynamic metering of sealant volumes, and also described herein is a corresponding method.The apparatus of the invention includes two containers for sealant components; a first drive, which is connected to two devices, each of which is able to convey one of the sealant components from its container; a drive controller; a mixing unit for mixing the sealant components conveyed from the containers, having an opening for applying the sealant to a component; and also, additionally, a compensating container with a compensating volume; and a second drive, which is connected to a piston which reaches into the compensating volume of the compensating container.The compensating container in this arrangement is connected to the mixing unit. The first drive and the second drive can be dynamically controlled jointly by the drive controller.
US11059069B2	Liquid material-discharging device A liquid material discharge device includes a discharge member made of a rod-shaped body, a liquid chamber which is wider than the discharge member and in which a tip portion of the discharge member is disposed, a discharge port in communication with the liquid chamber, a liquid feed path establishing communication between the liquid chamber and a liquid material storage container, a drive device driving the discharge member, and a main body. The liquid material discharge device further includes an elongate insert member that is removably inserted into the liquid feed path without cutting the communication between the liquid chamber and the liquid material storage container.
US11059068B2	Edge banding machine with detachable adhesive applying mechanism An edge banding machine includes a foundation, an adhesive applying mechanism, a motor, a chain guide and a chain. The adhesive applying mechanism is detachably attached to foundation and includes an adhesive tank and an adhesive shaft that extends into the adhesive tank and has a lower end provided with a first sprocket. The adhesive shaft draws adhesive from the adhesive tank. The motor is fixed to the foundation and has a power-take-off shaft that has a second sprocket. The chain engages with the first sprocket and the second sprocket. The chain guide is attached to the foundation and has a guide wheel extending into the chain for pushing against the chain, so that the chain can move between a tensioned position and a relaxed position.
US11059067B1	Sprinkler head replacement assembly An assembly for replacing sprinkler heads includes a sprinkler head housing assembly with a cap, a sprinkler head, a sprinkler head support assembly core, a plurality of spacers, and a base. The sprinkler head housing assembly enables replacement of a damaged inground sprinkler head.
US11059066B2	Coating booth A coating booth (101) for elements to be coated. The coating booth (101) comprises a passage between opposing vertical sides (107a, 107b, 108a, 108b) through which elements to be coated are conveyed. There is an entrance (105) at one end of the passage and an exit (106) at the other end of the passage. The coating booth (101) comprises a conveyor line (102) for supporting said elements to be coated and configured to convey said elements from the entrance (105) to the exit (106) along a straight pathway, and, a suction system. The opposing sides of the channel are symmetrical about the pathway. Sets of spray guns (103a, 104a, 103b, 104b) for spraying coating powder at the elements are positioned symmetrically either side of the straight pathway. The suction system comprises vertical suction inlets (109a, 109b) mounted opposite one another on each opposing vertical side of the passage, the suction system being configured to provide equal amounts of suction through each of the opposing vertical suction inlets (109a, 109b).
US11059063B2	Spray device having a replaceable cartridge The invention relates to the application of liquid active substances with the acid of a portable spray device. The subject matter of the present invention is a system comprising a portable spray device and a replaceable cartridge that contains an active substance concentrate. The invention also relates to method for applying a liquid active substance formulation. In addition, the invention discloses a replaceable cartridge that has a memory unit in which information is stored relating to an adjustable dilution ratio for the active substance concentrate contained in the cartridge. The invention also relates to a spray device comprising a control unit that can be read out a memory unit of cartridge attached to the spray device and, on the basis of the read out information, adjust a dilution ratio for the active substance concentrate contained in the cartridge.
US11059062B2	Airless adhesive spray gun and method of use The present invention provides an airless adhesive spray gun that atomizes adhesive sprayed through it without the use of air atomization. This system provides numerous enhancements to the prior art including limiting overspray “fog,” saving on sprayed material because of a more efficient spray pattern, and providing a stronger bond than that of the air-atomized spray guns of the prior art.
US11059061B2	Apparatus for increasing flux from an ampoule Ampoules for a semiconductor manufacturing precursors and methods of use are described. The ampoules include a container with an inlet port and an outlet port. The inlet port has a showerhead that the end within the container. The showerhead has at least two angled nozzles to direct the flow of gas within the cavity so that the gas flow is not perpendicular to the surface of a liquid within the ampoule.
US11059059B2	Electrostatic atomizing apparatus and electrically-charged water particle spraying apparatus An electrostatic atomizing apparatus includes: a liquid nozzle portion for releasing a liquid column into an open space; a liquid conduit portion for introducing pressurized liquid into the liquid nozzle portion; a liquid-side electrode disposed inside the liquid conduit portion for coming into contact with the pressurized liquid; a gas conduit portion made of an insulation material and having a gas nozzle portion disposed around the liquid nozzle portion for converting the liquid column into fine particles to generate an atomized stream by making a gas stream from the gas nozzle portion act at an atomization point of the liquid column released into the open space from the liquid nozzle portion; and a ring-shaped induction electrode disposed around the atomization point located in the open space and having an electrode conductor made of a conductive material and coated with an insulation material.
US11059057B2	Shower head having an overpressure valve A shower head, illustratively for a sanitary shower, including a shower head housing, a fluid inlet into the shower head housing, a shower jet outlet out of the shower head housing, a fluid duct within the shower head housing from the fluid inlet to the shower jet outlet, and an overpressure valve pressure-coupled to the fluid duct, including a movable valve body which, in case of an overpressure in the fluid duct, moves from a normal position to an overpressure position. The valve body is illustratively configured to be self-retaining in the overpressure position and returnable to the normal position by user operation, and/or the valve body acts position-dependent on a passage cross-section of the fluid duct, wherein the valve body reduces the passage cross-section in the overpressure position relative to the normal position.
US11059053B2	Centrifugal separator structure and assembly having an unjournaled axle member A centrifugal separator structure is configured for cleaning of crankcase gases from an internal combustion engine. The centrifugal separator structure includes a separator rotor configured for rotation about a centre axis arranged inside a stationary housing. The separator rotor includes an axle member configured for connection to a shaft of a driving device. A stack of separation discs is supported on the axle member. The axle member is un-journaled inside the stationary housing when the centrifugal separator structure is separate from the driving device. Further, an assembly includes the centrifugal separator structure and a driving device.
US11059044B2	Microfluidic determination of low abundance events Provided are microfluidic systems and methods for detecting, sorting, and dispensing of low abundance events such as single cells and particles, including a variety of eukaryotic and bacterial cells, for a variety of bioassay applications. The systems and methods described herein, when implemented in whole or in part, will make relevant microfluidic based tools available for a variety of applications in biotechnology including antibody discovery, immuno-therapeutic discovery, high-throughput single cell analysis, target-specific compound screening, and synthetic biology screening.
US11059030B1	Catalyst compositions having enhanced acidity for bi-reforming processes Methods for bi-reforming over a modified red mud catalyst composition, one method including providing a methane feed in the presence of carbon dioxide and steam to react over the modified red mud catalyst composition at increased temperature and increased pressure to produce synthesis gas comprising H2 and CO, the composition comprising red mud material produced from an alumina extraction process from bauxite ore; nickel oxide, the nickel oxide present at between about 5 wt. % to about 40 wt. % of the modified red mud catalyst composition; and a Periodic Table Group VIB metal oxide, the Group VIB metal oxide present at between about 1 wt. % and about 30 wt. % of the modified red mud catalyst composition.
US11059029B2	Method for producing an adsorption agent for treating compressed gas and an adsorption device provided with such an adsorption agent A method for manufacturing an adsorption agent for treating compressed gas, which includes the steps of providing a monolithic supporting structure; producing a coating suspension that includes an adsorbent; applying the coating suspension on the supporting structure to form a coating; applying a thermal treatment to the coated supporting structure in order to sinter the coating.
US11059027B2	Microporous carbon materials to separate nitrogen in associated and non-associated natural gas streams The present invention relates to a process for the manufacture of microporous carbon materials to perform selective separations of nitrogen in gas mixtures such as hydrogen sulfide, carbon dioxide, methane and C2, C3 and C4+ hydrocarbons, with high efficiency, shaped of microspheres or cylinders from copolymers of poly (vinylidene chloride-co-methyl acrylate) with density of 1.3 to 1.85 g/cm3 or poly (vinylidene chloride-co-vinyl chloride) with density of 1.3 to 1.85 g/cm3, using two stages. The first stage consists of a surface passivation of the material by chemical attack in a highly alkaline alcohol solution, with the aim of effecting a precarbonization on the surface of the copolymer that during the pyrolysis process is not deformed and gradually develops microporosity. The material of the first stage presents, in the layer, percentages between 55% to 85% carbon, between 5% to 20% oxygen, and between 10% to 40% chlorine. The interior of the material presents lower percentages of carbon, between 30% to 65%, oxygen in the amount of between 2% to 6%, and chlorine in the amount of between 30% to 60%. The second stage consists of the gradual pyrolysis of the passivated copolymer, with the aim of developing microporosity and high surface area values; as well as during the melting and gas dehydrohalogenation stages thereof, the deformation of the material is avoided. The morphology of the copolymers are microspheres of 125 to 225 micrometers, or cylinders of 4 mm in height and 3 mm in diameter, which after pyrolysis reduce its size by 35% with respect to the initial one. The material of the second stage, which is already microporous carbon material, presents in the layer percentages between 90% to 100% carbon and between 10% to 0% oxygen.
US11059021B2	Process for the preparation of intermediates useful in the preparation of non-ionic contrast agents The invention relates to a process for the preparation of one or more intermediate chemical compounds useful in the preparation of non-ionic contrast agents wherein the process is carried out continuously using one or more flow procedures.
US11059018B2	Turbomachine chemical reactor and method for cracking hydrocarbons in a process fluid Chemical reactors (10) and methods crack hydrocarbons in process fluids by accelerating the process fluid to a velocity greater than Mach 1 with an axial impulse impeller (40) and generating a shock wave (90) in the process fluid by decelerating it in a static diffuser (70) having diverging diffuser passages (72). Temperature increase of the process fluid downstream of the shockwave cracks the entrained hydrocarbons in a single pass, through a unidirectional flow path (F), within a single stage, without recirculating the process fluid for another pass through the same stage. In some embodiments, the turbomachine chemical reactor (110) has multiple successive stages of one or more axial impulse impellers (40A, 40B), paired with a diverging passage, static diffuser (70). Successive stages crack additional hydrocarbons by successively raising temperature of the flowing process fluid.
US11059015B2	Microcapsules modified with nanomaterial for controlled release of active agent and process for preparation thereof The present invention disclosed a microcapsule modified with nanomaterial for controlled release of active agent comprising; a core comprising active agent and said polymer shell encompassing said core; characterized in that said polymer shell is made up of polymer nanocomposite and a process for the preparation thereof.
US11059014B2	Nanocluster liquid dispersion, nanocluster film, nanocluster solid dispersion, method for producing nanocluster liquid dispersion, and device for producing nanocluster liquid dispersion The present invention relates to a nanocluster liquid dispersion where nanoclusters with a predetermined number of atoms are dispersed.
US11059011B2	Reforming device and reforming system A reforming device 1 for producing a reformed gas from a methane-containing gas containing methane and carbon dioxide includes a reforming reaction tube 10 containing a catalyst layer 12 filled with a reforming catalyst 12a for reforming the methane-containing gas, and a multilayer pipe 103 for spraying a cooling fluid to an outer peripheral surface of the reforming reaction tube 10 at a position corresponding to a gas inlet of the catalyst layer 12 in a length direction of the catalyst layer 12.
US11059007B2	Rotor of a dual centrifuge The invention relates to a rotor (10) of a dual centrifuge wherein the rotor has a rotor head (12) and an additional rotational mechanism for at least one rotational unit (22) which is provided in the rotor head (12) and comprises a bearing unit (70) and a rotational head (24) that is connected to the bearing unit (70) which is rotatably mounted and can be driven relative to the rotor head (12) by an additional rotational mechanism, an opening (16) for the rotational unit (22) being provided in which the rotational unit is accommodated and by means of which the bearing (70) is arranged such that it is fixed relative to the rotor head (12). The invention is characterized in that the rotational unit (22) has a housing (26) in which the bearing unit (70) is accommodated and in which the rotational head (24) engages, and in that the housing (26) and the rotational head (24) form, with bearing unit (70), a structural unit, the housing (26) being mounted such that it cannot rotate relative to the rotor head (12) and such that it can be detached from the rotor head.
US11059002B2	Pivoting gas/liquid dissolution device A gas/liquid dissolution device includes: a dissolution case of a cylindrical shape; an introduction port outside a side surface of the dissolution case, where a dissolution water is introduced into the dissolution case and a different kind of gas is mixed through the introducing port; a gas/liquid separation inducer in the dissolution case, the gas/liquid separation inducer inducing the dissolution water and an insoluble gas introduced into the dissolution case to be separated to a gas and a liquid by a centrifugal force; and a discharge port outside an end portion of the dissolution case. The dissolution water and the insoluble gas are discharged from the dissolution case through the discharge port.
US11058996B2	Porous hollow fiber membrane An object of the present invention is to provide a porous hollow-fiber membrane satisfying both high strength and high pure-water permeation performance and at the same time, having high bending resistance. The present invention relates to a porous hollow-fiber membrane including a fluororesin-based polymer, in which the porous hollow-fiber membrane has a columnar texture oriented in a longitudinal direction of the porous hollow-fiber membrane and when a photograph of a cross-section parallel to the longitudinal direction of the porous hollow-fiber membrane is binarized into a structure portion and a void portion, the following 1) and 2) are satisfied: 1) a proportion of an area of the void portion is from 20 to 50%, and 2) a value obtained by dividing a total of peripheral lengths of the void portions by a total of areas of the void portions is 2.0 μm−1 or less.
US11058991B2	Adsorption drying unit A pressure swing adsorption drying unit which includes at least one of a sensor (46′) for the ambient temperature to which the drying unit is exposed, and a sensor (46) for the temperature of the gas stream in the inlet line (2) to the unit, and the threshold value for the humidity of the gas stream in the outlet line (42) is determined dependent on the measured temperature.
US11058988B2	Ventilating air conditioning apparatus An energy-efficient, space-saving, low-cost, waste-heat-utilizing ventilating air conditioning apparatus uses a honeycomb rotor having a function of adsorbing or absorbing contaminants such as carbon dioxide and VOC gas. The honeycomb rotor is disposed in a rotor rotating device having at least a processing zone and a re-generation desorption zone. Air to be processed is passed through the processing zone to remove contaminants such as carbon dioxide to produce supply air. Water is directly sprayed or dropped into a heat exchanger provided at an entrance of the re-generation desorption zone to evaporate the generated water film by heating. The generated saturated steam is introduced for desorbing carbon dioxide and pollutants, and the stream is discharged the stream outdoors. The ventilating air conditioning apparatus can operate without the energy loss associated with ventilation.
US11058977B2	3D printed staged filtration media packs A filter medium includes a plurality of layers each including an undulating strip of solidified material.
US11058976B2	Valve-sensor assembly A valve-sensor assembly for a filter assembly that filters water from a fluid. The valve-sensor assembly includes a sensor body and a drain valve body. The sensor body includes a filter element engagement portion having a hollow interior that extends longitudinally through a length of the sensor body and a protrusion that extends circumferentially along an exterior surface of the filter element engagement portion. The sensor body further includes one or more water-in-fluid sensors provided at the exterior surface of the filter element engagement portion. The drain valve body includes a main body having a drain port, and a valve extending from the main body and extending at least partially within the hollow interior. The valve has an interior passage in fluid communication with the drain port.
US11058975B2	Filtering apparatus A filtering apparatus has filtering elements (11) in a filter housing (1), a filter inlet (7) and a filter outlet (9). During filtration, one of the filter elements (11) can be back-flushed by a back-flushing device (45, 49), having a pressure control device (19). The pressure control device has a hydraulic accumulator (19), with a fluid chamber (47) fillable during filtration with clean fluid and connectable for back-flushing via a back-flushing guide (45) to the clean side (29) of the filtering element (11) to be cleaned. For back-flushing, a further fluid chamber (48) of the hydraulic accumulator (19) is subjected to gas pressure. By resultant movement of a separator (59) of the hydraulic accumulator (19), the filling amount of the clean fluid is dispensed for the back-flushing.
US11058971B2	Oil-water separator for offshore wind farm Disclosed is an oil-water separator for offshore wind farms. The separator is arranged between an oil drain pipe and an accident oil tank, and has a cylindrical structure, and includes an oil storage compartment, a water storage compartment and a partition plate between them. The disclosure can ensure that the accident oil tank is empty under normal operating conditions so that a platform weight is reduced; and an insulation and an electric heating treatments are only performed at the oil-water separator to save insulation project quantity and energy consumption for heating; and a two-stage oil-water separation is achieved in the oil-water separator to avoid mixing oil droplets into water discharged from a water outlet.
US11058970B2	Vise for column and column system for chromatography A vise for column, for attaching a plug to a column tube of a column for chromatography comprising the column tube and the plug to be attached to one end of the column tube, is provided. The vise comprises a column supporter configured to be able to support a part of the column for chromatography, a main body configured to be connected to the column supporter and extending from the column supporter by a predetermined distance, and a column presser configured to be supported at another end of the main body opposite to one end to which the column supporter is connected, and configured to be movable toward and away from the column supporter, and configured to be able to press the plug against the column tube.
US11058968B2	Salt removal and transport system and method for use in a mono ethylene glycol reclamation process Systems and methods for removing solids from a process stream being fed into a flash separator include a solids fluidization device and a solids removal device. The solids fluidization device at the bottom end of the fluid column of the flash separator introduces a swirling motive fluid within the fluid column, while the solids removal device located above the solids fluidization device removes the slurry created by the swirling motive fluid. Systems and methods for fluidizing solids in the fluid column of a flash separator include a solids fluidization device that introduces a swirling motive fluid within the fluid column, means to limit the upward movement of the swirling motive fluid, such as a valve, and removing the solid slurry produced by the swirling motive fluid.
US11058966B2	Suspended theater with edge actuators A suspended theater system uses a seat moving machine comprising a passenger seat assembly disposed in between opposing seat supports which raise and lower the passenger seat assembly. One or more passenger seat beam rotators are operative to rotate the passenger seat assembly to change the pitch independently of the raising and lowering. In embodiments, rather that the seat rows being pivoted up with a rotating floor, a rotate function alters their mutual positions to one another while the lift function is taking place which brings the back seat rows up and over the front seat rows, allowing control over mutual row position during lift and in the show. Though no cables are involved, by combining the motions of lift and rotate and without any further equipment, an immersive theater system comprising the seat moving machine still employs seating that is suspended.
US11058964B2	Toy A toy for replaying music or a spoken story, includes a loudspeaker or a loudspeaker terminal, a sensor which within a region of its surroundings can detect a property or a change in a property of said surroundings, and a control unit that can drive the loudspeaker or the loudspeaker terminal to replay music or a spoken story if the sensor senses, within a region of its surroundings, a specific property or a specific change in a property of the surroundings or when the control unit detects a specific change in the property detected by the sensor. The toy also includes a toy identification and a mechanism for transmitting a signal that is dependent on the toy identification.
US11058950B2	Methods and systems for spectating characters in virtual reality views Methods and systems for spectating a live video game are presented. In one method embodiment, an operation includes providing an interface for presenting an overhead view of an interactive environment of a video game on a head mounted display (HMD). The method also provides an operation for providing a magnifying window for displaying a magnified view of the interactive environment, where the magnified view is associated with a second vantage point that is closer to the interactive environment than is a first vantage point of the overhead view. The method further provides an operation for tracking a real-world position of a controller of the spectator and moving the location of the magnifying window to correspond to the real-world position of the controller.
US11058948B1	Predictive modeling for multiplayer gaming Machine learning is used to generate and update predictive models configured to predict the positions, orientations, or actions of various gameplay elements capable of being controlled by players of a network-based multiplayer game. A gaming server can send a trained predictive model to each player device actively involved in a gaming session. Those devices can use the predictive model to predict the positions and orientations of various gameplay elements, where the actual data will not be received for a period of time due to latency of transmission over at least one network connection. When the actual data is received, the game state and gameplay action can be corrected or initiated as appropriate, enabling the overall gameplay experience to be smoother and more enjoyable. The gameplay and prediction data can be analyzed to further train or improve the models.
US11058947B2	User-based mini-game generation and distribution A mini-game may be generated by recording game data during play of a video game on a computer game system, suspending play of the video game in response to a first input to the computer game system, rewinding the recorded game data to a start point in response to a second input to the computer game system, and uploading recorded game data representing a state of the video game at the start point to a remote mini-game distribution system. The mini-game data may be distributed to other game playing systems. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. This abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
US11058941B2	Game apparatus A game apparatus provides a game using three-dimensional game objects rollable regardless of their orientation, and includes a circulating mechanism configured to circulate the three-dimensional game objects. The circulating mechanism includes: a conveyor device configured to transport the three-dimensional game objects from a first position to a second position higher than the first position; a first path configured to move the three-dimensional game objects from the second position to a third position lower than the second position; a supply path for supply of a part of the three-dimensional game objects to a game object utilizer that uses the supplied three-dimensional game objects in the game, the part entering the supply path at a position between the second position and the third position; and a second path configured to move a part of the three-dimensional game objects not entering the supply path, to the first position lower than the third position.
US11058940B2	Sports glove A sports glove includes a wrist portion defining an opening, a palm portion having a palm side and a backside, a thumb stall and a plurality of finger stalls extending from the palm portion. The palm side comprises a fabric layer bordering an interior of the glove, and a resilient polymer layer on an outer surface of the fabric layer. At least first and second grooves are formed into the polymer layer. The finger stalls include an index finger stall, a middle stall, a ring finger stall and a pinky stall. The first groove forms a thumb base bending line extending from at or adjacent to the opening along the palm portion to a juncture of the thumb stall and the index finger stall. The second groove forms an upper mid-palm bending line extending across the palm portion adjacent at least the pinky finger stall and the ring finger stall.
US11058936B1	Exercise rack enclosure system An exercise rack enclosure system for providing an exercise rack which is concealable within an enclosure. The exercise rack enclosure system generally includes an enclosure including an interior space. An exercise rack is pivotably connected to the enclosure within the interior space. The exercise rack is adjustable between a collapsed position, in which the exercise rack is completely positioned within the interior space of the enclosure, and an extended position, in which the exercise rack extends out of the interior space of the enclosure for use. The enclosure may optionally include one or more doors for concealing the interior space and exercise rack when not in use. Various attachments may be stored in the enclosure and removably connected to the exercise rack for performing a wide range of exercise moves.
US11058933B2	Golf putter A golf putter head that can improve the golfer's ability by providing function features that create a consistent setup of putter head position in relation to the golf ball and golfer position in relation to the putter. Once the setup is consistent, further increase in the consistency of the golfer's stroke can be attained through building muscle memory. From the putter stroke, the hitting face can impart an accurate forward motion to the golf ball upon being stricken by the putter head. The putter can provide tactile feedback to the golfer during the golf swing while imparting a forward roll to the golf ball upon striking and can simplify the visual alignment of the putter head to the golf ball.
US11058931B2	Multi-material iron golf club head Described herein is a tour iron having a golf club head with a faceplate, a body, and an insert. A sole, top rail, rear, and the faceplate enclose a cavity within the body. The cavity can house the insert. The insert can comprise a low-density material, allowing weight to be concentrated around the peripheral edge of the golf club head. The rear of the golf club head has an inflection seam running from the heel to the toe. The golf club head has an upper portion, above the inflection seam and a lower portion below the inflection seam. The lower portion can have a depth greater that the upper portion depth. The faceplate, body, and insert can be formed of different materials having different densities. The golf club head has a comparatively high moment of inertia and a low center of gravity. Other embodiments and methods are described herein.
US11058930B2	Golf club heads with turbulators and methods to manufacture golf club heads with turbulators A golf club head includes a crown surface having an apex at a highest point and extending between the face, the rear, the heel and the toe of the golf club head. The golf club head also includes a plurality of crown turbulators projecting from the surface of the crown and located at least partially between the leading edge and the apex, wherein the height of each turbulator decreases from the leading edge toward the rear portion.
US11058924B1	Method and system utilizing imaging analysis for golf balls A method and system for determining concentricity of a multiple layer golf ball are disclosed herein. One or more images of a golf ball are generated using an X-ray source, a camera or a digital detector, and an image intensifier. An edge detection algorithm is preferably utilized. The method also includes calculating Y,Z center coordinates of the a best fit diameter or ellipse of the inner edge layer and outer edge layer of the multiple layer golf ball.
US11058907B2	Method of delivering a fire extinguishing agent A fire suppression system is provided including at least one nozzle configured to expel a fire suppression agent into a space. A storage container includes a fire suppression agent and a first pressurized gas at least partially dissolved within the fire suppression agent. At least one canister contains a second pressurized gas. A piping system is configured to fluidly couple the at least one canister to the storage container and to fluidly couple the storage container to the at least one nozzle. When the fire suppression system is inactive, the fire suppression agent within the storage container is pressurized to a storage pressure. The storage pressure is greater than a vapor pressure of the fire suppression agent such that first pressurized gas dissolves into the fire suppression agent. When the fire suppression system is active, propellant pressure in the piping system exceeds the storage pressure of the fire suppression agent.
US11058906B2	Sweeping and fire extinguishing device The present invention relates generally to the technical field of smart home. More particularly, it relates to a sweeping and fire extinguishing device comprising a sweeping robot, a fire extinguishing mechanism and a body frame, wherein said fire extinguishing mechanism is disposed in a space surrounded by the body frame while said sweeping robot is disposed under the fire extinguishing mechanism. Said sweeping robot comprises a body, a processer, an abutting hole and a camera, wherein an abutting terminal is disposed in said abutting hole. Said camera and the abutting terminal are both electrically connected to the processor; Said fire extinguishing mechanism comprises a supporting platform and a clamping mechanism, wherein said supporting platform comprises an abutting block on its lower end and said abutting block comprises a connecting terminal. Said supporting platform comprises a swinging mechanism for placing a fire extinguisher. Said clamping mechanism is disposed on the control handle of the fire extinguisher. Said clamping mechanism is wirelessly connected with the processor; Said body frame comprises a lifting mechanism which is connected with the swinging mechanism. The invention realizes automatic fire extinguishing by integrating the sweeping robot and the fire extinguishing mechanism into a simple structure, which takes up less space and reduces the cost.
US11058903B2	Methods for identifying and treating cachexia or pre-cachexia using an inhibitor of rage The invention provides markers indicative of pre-cachexia, compositions and methods for identifying patients with a molecular signature indicative of pre-cachexia; a culture system that reproduces the cachetic process in cells in vitro, which facilitates the screening and identification of therapeutic agents useful for disrupting (slowing, reducing, reversing, or preventing) the progression of pre-cachexia to refractory cachexia; as well as therapeutic agents identified using the culture system of the invention.
US11058901B2	Ultrasound therapy system In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.
US11058895B2	Collimator and medical robot including the same Provided is a collimator including a base unit configured to form a radiation path of light; a pair of first moving members rotatably installed in the base unit; a pair of second moving members movably installed in the base unit; and an actuator configured to externally receive power and transmit the power to the first moving members and the second moving members, wherein a first space may be formed between the first moving members, a second space may be formed between the second moving members, and the light may pass through a radiation area corresponding to an overlapping area of the first space and the second space.
US11058890B2	Method and apparatus for cyclo-scanner using surface emitting lasers or LEDs A handheld device for delivering therapeutic light toward an eye of a patient includes a device housing that is configured to be held by a user in delivering the therapeutic light, a plurality of light sources disposed within the device housing, and an array of lenses disposed near the distal end of the device housing. Each light source is configured to independently emit a beam of therapeutic light and each lens of the array is aligned with a respective light source so that each beam of therapeutic light that is emitted from the respective light sources is focused and directed by the respective lenses of the array to target tissue of the eye in order to therapeutically treat to the target tissue.
US11058887B2	Devices, systems, and methods for non-invasive chronic pain therapy Presented herein are devices and systems as well as the methods of using the same for the purpose of reducing and/or ameliorating the sensation of pain, specifically, chronic pain. Particularly, in one aspect, the devices, systems, and their methods of use disclosed herein are effective for reducing peripheral nerve pain, such as resulting from traumatic nerve injury and other types of nerve damage.
US11058882B2	Implantable medical devices having circuitry located adjacent to header-related structures Implantable medical devices include circuitry positioned adjacent to header-related structures, rather than having the header and related structures sitting atop the position of the circuitry within a device housing. A circuit board within the device housing may be positioned adjacently to a lead bore of the header. Feedthrough conductors may extend from the circuitry to conductors of the header while being positioned adjacently to the circuit board. Lead frame conductors may extend to the electrical connectors of the lead bores while also being adjacent to the upper portion of the circuitry. Device height may be reduced by having the circuitry be positioned adjacent to one or more of the various header-related structures.
US11058877B2	Apparatus and method for the automated control of transcutaneous electrical nerve stimulation based on current and forecasted weather conditions Apparatus for transcutaneous electrical nerve stimulation in a user, the apparatus comprising: a stimulator for electrically stimulating at least one nerve with at least one stimulation pulse; a controller connected to the stimulator for controlling at least one characteristic of the at least one stimulation pulse; an analyzer for identifying the current and future presence of pain-altering patterns based on weather and/or environmental factors; and a processor connected to the analyzer and the controller for modulating the at least one characteristic of the at least one stimulation pulse according to the pain-altering patterns identified by the analyzer.
US11058876B2	Device and implantation system for electrical stimulation of biological systems The present specification discloses devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.
US11058873B2	Intra-cardiac implant, cardiac pacemaker, implantation device and method for implanting intra-cardiac implant Disclosed is an intra-cardiac implant, a device and a method for respectively implanting two connected intra-cardiac implants to two cardiac chambers at one time. The intra-cardiac implant comprises a columnar housing including a sidewall, a first terminal and a second terminal, a first connecting portion located at the first terminal of the housing and configured to connect with the implantation device; and a hook body mounted at the sidewall of the housing and comprising a fixed end on the sidewall and a free end stretching from the fixed end, wherein the hook body is configured to form a clamping structure with the sidewall, the free end comprises a tip on its top for piercing the myocardium, and the intra-cardiac implant is clamped between the hook body and the sidewall, so that the intra-cardiac implant is fixed on the myocardium.
US11058865B2	Catheter pump A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.
US11058860B2	Transfer device valve A valve is disclosed, the valve comprising a housing having an first opening and a second opening, and an elastomeric member positioned in the housing, the elastomeric member comprising a thickness, a continuous peripheral wall projecting from the thickness, and a slit extending through the thickness, a continuous portion of the peripheral wall creating a continuous sealable contact with the housing and partitioning the housing into an upper section and a lower section, the elastomeric member configured such that upon creating a pressure differential between the upper section and the lower section of the housing causes either: (i) the peripheral wall to deflect from the housing permitting fluid flow around the elastomeric member; or (ii) the slit to open permitting fluid flow through the elastomeric member. Methods using the valve are also disclosed.
US11058859B2	Apparatus and methods of dispensing fluid intravenously and flushing lines of intravenous fluid administration systems Apparatus and methods of dispensing fluid intravenously to a subject, and of flushing a line of an intravenous fluid administration apparatus, are provided. The apparatus may include a reservoir pump configured to operate in fluid communication with an upstream source of a first fluid and a downstream pressure-operated valve. The apparatus may also include a port connector configured to operate in fluid communication with at least the pressure-operated valve. The reservoir pump may also be configured to, during operation, automatically refill itself with the first fluid from the first upstream source. The downstream pressure-operated valve may be configured to operate in fluid communication with the reservoir pump and a second fluid source upstream of the pressure-operated valve, and to, during operation, dispense the first fluid to tubing downstream of the pressure-operated valve based on a pressure condition within the pressure-operated valve exceeding a threshold pressure.
US11058852B2	Interventional medical instrument, delivery apparatus, and interventional medical system An interventional medical system (10) comprises an instrument (100) provided with a plug head (120) and a delivery cable (200) provided with a cable head (211), and further comprises a locking sleeve (300) movably sleeved onto the delivery cable (200). The cable head (211) comprises at least one resilient locking piece (123) extending approximately away from a central axis of the cable head (211). When under a radial restraint applied by the locking sleeve (300), the plug head (120) abuts the locking piece (123) such that the plug head (120) is connected to the cable head (211), and when the locking sleeve (300) has moved relative to the delivery cable (200) such that the locking piece (123) is no longer radially restrained, the locking piece (123) elastically moves away from the plug head (120) such that the instrument (100) is separated from the delivery cable (200).
US11058851B2	Dilation delivery system for a medical device A kit including a sheath having a tubular body with proximal and distal ends, an axis extending between the ends and a wall defining a bore extending along the axis to the distal end of the body. A delivery tube having proximal and distal ends and a lumen is adapted for disposition within the bore of the sheath in sealing engagement with the sheath, the delivery tube being slideable distally relative to the sheath. An elongated cannula having proximal and distal ends and a lumen is adapted for disposition inside the lumen of the delivery tube and an elongated dilator is adapted to fit within the lumen of the cannula with a proximal portion of the dilator extending proximally beyond the proximal ends of the cannula and delivery tube and in sealing engagement with the delivery tube proximal to the cannula.
US11058850B2	Catheter hole having a flow breaking feature A peripheral catheter having a catheter tip diffuser for reducing an exit velocity of an infusant within the catheter. Pluralities of diffusion side holes are provided on the tip portion of the catheter. Some examples further include pluralities of annularly arranged, staggered diffusion holes provided on the tip portion of an intravenous catheter to streamline infusant issued from the diffusion holes. An inner surface of each diffusion hole is further angled relative to the inner surface of the catheter lumen such that an infusant within the lumen exits the catheter though the diffusion holes at an angle less than 90°.
US11058844B2	Medical tubes and methods of manufacture The disclosure relates to medical tubes and methods of manufacturing medical tubes. The tube may be a composite structure made of two or more distinct components that are spirally wound to form an elongate tube. For example, one of the components may be a spirally wound elongate hollow body, and the other component may be an elongate structural component also spirally wound between turns of the spirally wound hollow body The tube need not be made from distinct components, however. For instance, an elongate hollow body formed (e.g., extruded) from a single material may be spirally wound to form an elongate tube. The elongate hollow body itself may in transverse cross-section have a thin wall portion and a relatively thicker or more rigid reinforcement portion. The tubes can be incorporated into a variety of medical circuits or may be employed for other medical uses.
US11058839B2	Sealing cushion with inner membrane A sealing cushion for a respiratory mask assembly has a patient interface portion having a resiliently deformable membrane for engagement with a patient's face, and an aperture formed therein for receiving a nasal and/or mouth region of the patient's face. An inner surface of the deformable membrane comprises a plurality of projections arranged in separate groups of projections positioned in a plurality of localized regions of the deformable membrane. The projections in each of the separate groups of projections are arranged such that each projection in the group of projections engages with an adjacent projection in the group of projections when the deformable membrane is deformed during engagement of the deformable membrane with the patient's face, in use, thereby providing the deformable membrane with an increased resistance to further deformation.
US11058837B2	Patient tube securement apparatus for securing a patient tube to a patient A patient tube securement apparatus is disclosed that may be used for oral or nasal intubation of a patient.The apparatus may comprise an endotracheal tube securement apparatus for securing an endotracheal tube to a patient, the apparatus comprising a dermal patch arranged to be positioned on the skin of the patient, and at least one tube holder on the dermal patch.The apparatus may comprise a patient tube securement apparatus for securing a patient tube to a patient, the apparatus comprising a dermal patch arranged to be positioned on the skin of the patient, and at least one tube holder on the dermal patch.Examples are provided in which the tube holder is adjustably mounted on the dermal patch such that the position of the tube holder on the dermal patch can be adjusted without removing the dermal patch from the skin of the patient.
US11058835B2	Vaporizer for vaporizing a constituent of a plant material Apparatus and methods are described for use with a vaporizer that vaporizes at least one active ingredient of a plant material. In response to receiving a first input to the vaporizer, the plant material is heated, in a first heating step. An indication of the temperature of the plant material is detected, and, in response to detecting an indication that the temperature of the plant material is at a first temperature, the first heating step is terminated, by withholding causing further temperature increase of the plant material. The first temperature is less than 95 percent of the vaporization temperature of the active ingredient. Subsequently, a second input is received at the vaporizer. In response thereto, the plant material is heated to the vaporization temperature, in a second heating step. Other applications are also described.
US11058832B2	Single dose dry powder inhaler A dry powder inhaler may include a housing having a lower housing part defining at least one air inlet and at least one air outlet. At least one container may be disposed in the lower housing part. The at least one container may include a cavity for a dry powder drug. A chamber may be disposed above the at least one container for deaggregation of the dry powder drug after emptying of the dry powder drug from the cavity. Upon inhalation by a user at the at least one air outlet, air may flow from the at least one air inlet into and through the chamber to empty the dry powder drug from the cavity and convey the dry powder drug to the at least one outlet.
US11058830B2	Assistive device for subcutaneous injections or implants An assistive device for subcutaneous injections or implants. The assistive device is placed under a blood pressure cuff that displaces the skin and subcutaneous tissues of a patient at an insertion site in order to allow guided insertion of a needle or implant applicator into a subcutaneous fat layer. The skin and subcutaneous tissue is displaced or drawn, via pressure applied by the blood pressure cuff, through an injection window of a device body into a hollow cavity of the device body. A guide channel leads from a front side of the device body into the hollow cavity, and an applicator of an adapter is inserted through the guide channel into the subcutaneous fat layer.
US11058828B2	Safe pen needle A safe insulin pen needle has a structure effectively circumvents the risk of the needle head protection failure caused by the rotation of the insulin pen during the needle pulling process by some users through a first check flange on one side of a first initial fixing position matched with a first elastic clamping jaw. The safe insulin pen needle effectively circumvents the safety risk that the needle tail tends to damage the user through the needle tail protection structure and, at the same time, effectively circumvents the risk that the needle tail protector will rotate and thus the needle tail protection will fail during the separation of the insulin pen from the insulin pen needle through a second check flange on one side of a second initial fixing position matched with a second elastic clamping jaw.
US11058827B2	Shroud lock A shroud lock for locking a position of a needle shroud relative to a housing of an autoinjector, includes a shroud beam arranged on the needle shroud and biased radially outwards, a stop arranged within the housing, a recess arranged proximal of the stop, and a cap coupled to the housing and adapted to prevent distal translation of the needle shroud relative to the housing. At least a portion of the shroud beam is within the recess when the cap is in place and, the shroud beam abuts the stop after the needle shroud is locked relative to the housing of the autoinjector. The disclosure further relates to an autoinjector and to a method for assembling such an autoinjector.
US11058824B2	Multiple dosage injector A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
US11058820B2	Drug delivery device There is provided drug delivery devices comprising a drug container assembly with a needle and automatic needle insertion and drug delivery mechanisms. Aspects of the devices described include a noise-generation mechanism to indicate the completion of drug delivery, a mechanism for triggering drug delivery following needle insertion, front-end activation of the device and a safety mechanism for covering the needle after use and methods of assembly of the devices.
US11058819B2	Auto-injector device An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.
US11058817B2	Administration apparatus for medical use An expansion/compression mechanism of a piston rod assembly is composed of a bush shaft, a first cylindrical piston rod that is screwed with the bush shaft, a second cylindrical piston rod that is screwed with the first piston rod, and a piston rod holding member for housing the bush shaft and these piston rods. Therefore, the piston rods move linearly in multiple stages.
US11058815B2	Medical access ports, transfer devices and methods of use thereof An access port system, comprising an implantable access port, the access port including an access port body, an access port needle and a fluid flow passage provided within the body and the needle; wherein the needle is fully containable within the body, and the needle is exposable outside the body; wherein the needle is arranged within the body to penetrate outwardly of the subject from within the subject when the access port is implanted in the subject; wherein, when the needle is exposed outside the body, the fluid flow passage is open to a flow of a fluid within the access port in at least a direction entering the access port through the needle and thereafter exiting the access port from the body; and wherein the assess port includes at least one sensor configured to detect the fluid within the fluid flow passage.
US11058812B2	Intravenous bag attachment An intravenous bag attachment for automatically flushing remnants out from an intravenous line after the contents of a connected intravenous bag have emptied out. The attachment includes a container having a tubular member in fluid communication with an interior volume designed to hold a flushing solution. The tubular member is designed to create an opening and be inserted into an intravenous bag, and to act as a float valve that will remain closed while the amount of liquid remaining in the intravenous bag is above a predefined threshold, and that will open once the amount of liquid remaining in the intravenous bag falls below the predefined threshold. The float valve further includes a ball float designed to keep the tubular member upright, such that the float valve is closed, and to allow the flushing solution to exit through the tubular member when the float valve is open.
US11058799B2	Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same An orthopedic implant having a metal surface and a calcium phosphate layer disposed on at least part of the metal surface is described. The calcium phosphate layer has an average crystallite size of less than about 100 nm in at least one direction and dissolves for more than 2 hours in vitro. The calcium phosphate layer is substantially free of carbonate. The coating, which is formed on a sodium titanate surface, has increased shear strength and tensile strength. The coating is formed by a solution deposited hydroxyapatite process under inert conditions. The pH of the solution varies by less than 0.1 pH unit/hour during coating formation.
US11058795B2	Semipermeable membrane and method of manufacturing the same The present disclosure relates to a semipermeable membrane. The present disclosure aims to provide a semipermeable membrane having tolerance against a decrease over time in substance permeability. The present disclosure provides a semipermeable membrane containing a resin. The permeation rate of albumin in the semipermeable membrane is no lower than 30%. The albumin adsorption amount obtained when the semipermeable membrane measuring 1 cm on each side is immersed in a 0.1% albumin solution for 90 minutes is no greater than 10 μg/cm2. The water permeation amount obtained when water is sucked through the semipermeable membrane at a negative pressure of 3±0.2 kPa is expressed by no smaller than 1,000 L/(m2 hour). The semipermeable membrane can isolate a cell from an external environment.
US11058791B2	Thin nanocomposite film for use in an absorbent article A thin nanocomposite film for use in an absorbent article is provided. The film contains an ethylene polymer, a nanoclay having an organic surface treatment, and a compatibilizer that includes an olefin polymer containing an ethylenically unsaturated carboxylic acid monomer. The present inventors have discovered that through selective control over the particular type and concentration of the components used to form the film, as well as the manner in which it is formed, the modulus and tensile strength of the film can be significantly improved without having an adverse impact on its ductility.
US11058790B2	Electronic apparatus having photocatalytic filter An electronic apparatus capable of controlling the air purification performance of a photocatalytic filter according to an air volume of a blowing fan and a concentration of a specific gas. An electronic apparatus having a deodorizing performance recovery function of a photocatalytic filter. The electronic apparatus includes a blowing fan, a filter apparatus configured to purify air introduced by the blowing fan and a controller configured to adjust a current applied to the filter apparatus, wherein the filter apparatus comprises a light emitting module to which a plurality of light emitting portions configured to output ultraviolet light is mounted, a photocatalytic filter provided to face the light emitting portion and a support frame configured to support the light emitting module and the photocatalytic filter to be apart from each other by a predetermined distance.
US11058787B2	Scented frame clip An ornamental including first and second elongate members, a transverse member, and a reservoir. The first elongate member having an inner side and an opposing outer side. The second elongate member having an outer side and an opposing inner side facing the inner side of the first elongate member. The transverse member having a first end connected directly to a first end of the first elongate member and a second end connected directly to a first end of the second elongate member. The reservoir affixed to the second end of the first elongate member.
US11058784B2	Multipurpose ultraviolet floor curing devices Embodiments of the present disclosure disclose a multipurpose ultraviolet (UV) floor curing device. The device includes a mobile carriage, a UV panel, and a control device. The mobile carriage is configured to move on a floor applied with a photocurable coating. The UV panel is coupled to the mobile carriage and removably secures a plurality of radiation units configured to emit UV light of a predetermined intensity capable of curing the photocurable coating. The UV panel is configured to transition between a floor configuration and a non-floor configuration. The control device configured to drive the UV panel for the plurality of radiation units to project the UV light towards the ground substantially underneath the UV panel in the floor configuration and towards elevated surfaces proximate to the ground in the non-floor configuration.
US11058782B2	Apparatus, method, system and software product for hand sanitisation A method of implementing and using an apparatus (1a,1b,13,25) to achieve hand sanitisation by application of ozone. The apparatus has a disinfecting chamber (3,3′,110) with at least one port (2) adapted for insertion of at least one hand into the disinfecting chamber (3,110). A sensor (4) detects entry and/or exit of the hand (26) into the disinfecting chamber (3,110). An ozone water output (7,130) of an ozone water supply (8) is arranged to deliver ozone water to the at least one hand (26) when inserted into the disinfecting chamber (3,110). Control means (6) times start and stop of a discharge of ozone water from the at least one ozone water output (7,130) into the disinfecting chamber (3,110) when the at least one sensor (4) detects entry of the at least one hand (26) into the disinfecting chamber (3,110).
US11058779B2	Sirna/nanoparticle formulations for treatment of middle-east respiratory syndrome coronaviral infection The present invention relates to compositions and methods for siRNA therapeutics for prevention and treatment of Middle East Respiratory Syndrome Corona Virus (MERS-CoV) infections. The compositions include a pharmaceutical composition comprising siRNA cocktails that target viral genes and pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers.
US11058778B2	Nanoparticle pharmaceutical delivery system A method of preparing a nanoparticle pharmaceutical delivery system. A nanoparticle pharmaceutical delivery system. A method of preparing a targeted nanoparticle pharmaceutical delivery system. A targeted nanoparticle pharmaceutical delivery system.
US11058771B2	Vascular ulcer treatment A patch for treating vascular ulcers caused by excessive enzymatic activity may include a substrate configured to span a vascular ulcer as well as a linking material that is disposed relative to the substrate and has an affinity for an enzyme involved in causing the vascular ulcer. A magnetic material may be coupled to the linking material. In some cases, the enzymes involved in causing the vascular ulcer may become coupled to the linking material and thus become coupled to the magnetic material so that that the enzymes can be removed by applying a magnetic field in the proximity of the vascular ulcer. The enzymes may include matrix metalloproteinases.
US11058765B2	Means and methods for treating HSV The present invention relates to a vaccine composition comprising a multimeric complex of Herpes Simplex Virus (HSV) polypeptides for the treatment or vaccination against HSV. The present invention also relates to a vector comprising a polynucleotide encoding the HSV polypeptides and a host cell comprising the vector. The present invention further comprises a method for producing the vaccine composition.
US11058762B2	Immunogenic compositions and uses thereof This invention generally relates to immunogenic compositions that comprise an RNA component and a polypeptide component. Immunogenic compositions that deliver antigenic epitopes in two different forms—a first epitope from a pathogen, in RNA-coded form; and a second epitope from the same pathogen, in polypeptide form—are effective in inducing immune response to the pathogen. The invention also relates to a kit comprising an RNA-based priming composition and a polypeptide-based boosting composition. The kit may be used for sequential administration of the priming and the boosting compositions.
US11058756B2	Compositions and methods of treating autoimmune disease by reducing enterococcus The present invention relates to compositions and methods for treating or preventing an autoimmune disorder by reducing the amount or activity of Enterococcus sp. in a subject. In certain aspects, the present invention provides methods of diagnosing a subject as having an autoimmune disease or disorder by detecting an increased amount of Enterococcus sp. or anti-Enterococcus sp. antibodies in the subject.
US11058755B2	A*03 restricted peptides for use in immunotherapy against cancers and related methods The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11058754B2	Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11058751B1	Compositions for optimized RAS peptide vaccines The present disclosure provides for methods, systems, and compositions of nucleic acid and peptide sequences. The present disclosure provides for a nucleic acid sequence encoding two or more amino acid sequences selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID NO: 25, SEQ ID NO: 26, SEQ ID NO: 27, SEQ ID NO: 28, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 31, SEQ ID NO: 32, SEQ ID NO: 33, SEQ ID NO: 34, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO: 39, SEQ ID NO: 40, and SEQ ID NO: 41. The present disclosure also provides for an immunogenic peptide composition comprising two or more peptides selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID NO: 25, SEQ ID NO: 26, SEQ ID NO: 27, SEQ ID NO: 28, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 31, SEQ ID NO: 32, SEQ ID NO: 33, SEQ ID NO: 34, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO: 39, SEQ ID NO: 40, and SEQ ID NO: 41. The present disclosure further provides for a nucleic acid sequence encoding one or more amino acid sequences selected from the group consisting of SEQ ID NO: 42, SEQ ID NO: 43, SEQ ID NO: 44, SEQ ID NO: 45, SEQ ID NO: 46, SEQ ID NO: 47, SEQ ID NO: 48, SEQ ID NO: 49, SEQ ID NO: 50, SEQ ID NO: 51, SEQ ID NO: 52, SEQ ID NO: 53, SEQ ID NO: 54, SEQ ID NO: 55, SEQ ID NO: 56, SEQ ID NO: 57, SEQ ID NO: 58, SEQ ID NO: 59, SEQ ID NO: 60, SEQ ID NO: 61, SEQ ID NO: 62, SEQ ID NO: 63, SEQ ID NO: 64, and SEQ ID NO: 65. The present disclosure additionally provides for an immunogenic peptide composition comprising one or more peptides selected from the group consisting of SEQ ID NO: 42, SEQ ID NO: 43, SEQ ID NO: 44, SEQ ID NO: 45, SEQ ID NO: 46, SEQ ID NO: 47, SEQ ID NO: 48, SEQ ID NO: 49, SEQ ID NO: 50, SEQ ID NO: 51, SEQ ID NO: 52, SEQ ID NO: 53, SEQ ID NO: 54, SEQ ID NO: 55, SEQ ID NO: 56, SEQ ID NO: 57, SEQ ID NO: 58, SEQ ID NO: 59, SEQ ID NO: 60, SEQ ID NO: 61, SEQ ID NO: 62, SEQ ID NO: 63, SEQ ID NO: 64, and SEQ ID NO: 65.
US11058744B2	Composition for treating prostate cancer The present invention relates to a composition for treating prostate cancer and, more specifically, to a composition for treating prostate cancer, which contains a peptide derived from telomerase and is effective in inhibiting growth and metastasis of prostate cancer cells. In addition, the present invention provides a composition and method for treating prostate cancer, wherein, when prostate cancer is treated, docetaxel and the peptide derived from telomerase are co-administered, thereby having a synergetic therapeutic effect compared with administration alone. Particularly, the present invention provides a treatment method useful for patients who do not have a sufficient anticancer effect merely through administration of docetaxel alone and patients who have hormone resistance.
US11058739B2	Sebum control and anti-acne composition A method for reducing skin inflammation or reducing sebum production from sebaceous glands is disclosed. The method can include topically applying to skin in need thereof a composition comprising Psidium guajava fruit extract and Kunzea ericoides leaf extract, wherein topical application of the composition reduces skin inflammation or sebum production from sebaceous glands.
US11058734B2	Probiotic strains having cholesterol absorbing capacity, methods and uses thereof The invention relates to a probiotic strain selected from Lactobacillus reuteri V340 with accession number CECT and Bifidobacterium breve BT820 with accession number CECT 8606, or a variant of said probiotic strain having cholesterol-absorbing capacity, and to methods and therapeutic uses thereof. The invention also relates to compositions, pharmaceutical compositions, feeds or nutritional products comprising a probiotic strain selected from Lactobacillus reuteri V3401 with accession number CECT 8605 and Bifidobacterium breve BT820 with accession number CECT 8606, or a variant of said probiotic strain having cholesterol-absorbing capacity.
US11058728B1	Restimulation of cryopreserved tumor infiltrating lymphocytes The present disclosure provides methods for re-stimulating TIL populations that lead to improved phenotype and increased metabolic health of the TILs and provides methods of assaying for TIL populations to determine suitability for more efficacious infusion after re-stimulation.
US11058726B2	Peptides and scaffolds for use in immunotherapy against head and neck squamous cell carcinoma and other cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11058725B2	CA2 compositions and methods for tunable regulation The present disclosure provides drug responsive domains derived from human carbonic anhydrase 2 that can modulate protein stability for human interleukin 15 (IL15) payloads, as well as compositions and methods of use thereof.
US11058722B2	Chimeric antigen receptor comprising a cartilage-oligomeric matrix protein (comp) coiled-coil spacer domain The present invention provides a chimeric antigen-receptor (CAR)-forming polypeptide comprising: (i) an antigen-binding domain; (ii) a coiled-coil spacer domain; (iii) a transmembrane domain; and (iv) an endodomain. The invention also provides a multimeric CAR formed by association of a plurality of CAR-forming polypeptides by virtue of association of their coiled-coil spacer domains.
US11058699B2	Method and compositions for inhibition of double stranded DNA viruses A method of inhibiting double-stranded DNA virus infection is disclosed. In one embodiment, the method involves exposing a papillomavirus to an effective amount of an inhibitor selected from the group of G1, S, G2, and M cell cycle inhibitors. In another embodiment, the method involves administering an inhibitor selected from the group of G1, S, G2, and M cell cycle inhibitors to a susceptible tissue or cell.
US11058691B2	Nitric oxide releasing prostaglandin derivatives for treating normal tension glaucoma This invention provides a method of lowering intraocular pressure in a patient having normal tension glaucoma, comprising contacting an eye of a subject having normal tension glaucoma with a pharmaceutical composition comprising an effective amount of Nitric Oxide releasing prostaglandin derivatives of formula (I).
US11058690B2	Use of cytochrome bc1 complex inhibitor in preparing pharmaceutical composition A use of an inhibitor of the cytochrome bc1 complex for preparing a pharmaceutical composition which treats diseases related to smooth muscle spasms, inflammatory diseases, and relieves pain.
US11058687B2	Human papilloma virus as predictor of cancer prognosis Methods of treating a head and neck cancer are disclosed.
US11058686B2	5-(pyrimidin-4-yl)-2-(pyrrolidin-1-yl)nicotinonitrile compounds as IKKE, TBK1 and/or SIK2 kinases inhibitors The invention provides compounds of formula (I) wherein R is —CH3 or —CH2CH3 and pharmaceutically acceptable salts thereof. The compounds of formula (I) are useful in the treatment of diseases or disorders mediated by IKKE, TBK1 and/or SIK2 mechanisms in a subject, for example cancer and inflammatory and tissue repair disorders. The invention also provides uses of the compounds of formula (I) and compositions containing them. (Formula (I))
US11058683B2	Treating sexual desire disorders with flibanserin The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.
US11058682B2	Gastro-resistant formulation containing posaconazole The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
US11058680B2	Combinations of opioid/TLR4 antagonists and acetaminophen for use in the treatment of emotional pain and insomnia Disclosed are compositions for the treatment of emotional pain, physical pain, and insomnia comprising a compound comprising an opioid antagonist that treats pain by blocking Toll-like receptor 4 (TLR4). Examples of opioid antagonist include naltrexone and naloxone, and their use in the treatment, prevention, and reversal of pain.
US11058679B2	Dosage form of vinca alkaloid drug The present invention relates to a dosage form comprising an aqueous solution of a vinca alkaloid drug or its pharmaceutically acceptable salt in a flexible infusion container, and a light protective secondary packaging containing the flexible infusion container, wherein the dosage form is ready-to-infuse and wherein the aqueous solution is stable at room temperature.
US11058674B2	Drug for treating cocaine addiction or preventing recurrence of same The present invention provides a drug for treating cocaine addiction or preventing the relapse of the same. Specifically, the present invention provides a drug for treating cocaine addiction or preventing the relapse of the same containing (R)-2-{3-[1-(5-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)piperidin-4-yl]-2,3-dihydro-2-oxo-benzimidazol-1-yl}-N-methylacetamide or a pharmaceutically acceptable salt thereof.
US11058672B2	Pharmaceutical compositions and methods for producing low impurity concentrations of the same A composition having clevidipine as an active ingredient is described. The composition includes clevidipine as an active ingredient and an amount of the impurity H168/79 that is no greater than about 1.5%, or where the ratio between clevidipine and H168/79 is equal or above 60 to 1.
US11058671B2	Formulations and methods of manufacturing formulations for use in colonic evacuation Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.
US11058670B2	Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator Methods and compositions are disclosed for diagnosing a patient suspected of suffering from, and for treating a patient suffering from, a disorder such as hypercortisolemia, metabolic syndrome, pre-diabetes, diabetes, Cushing's syndrome, Cushing's Disease, hyperglycemia secondary to hypercortisolemia, a liver disease, a cardiac disorder, high blood pressure, a blood clotting disorder, a cancer, a psychological disorder, weight gain, a disorder of glucose control, a bone disorder (e.g., osteoporosis), hypogonadism, pseudoacromegaly, pituitary tumors, functional hypercortisolism, ACTH secreting tumors, peripheral neuropathy, dyslipidemia and other disorders.The methods and compositions include administration of a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator (GRM). The preferred heteroaryl-ketone fused azadecalin GRM is relacorilant ((R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone). In some cases, the GRM (e.g., relacorilant) is orally administered. In some cases, the GRM (e.g., relacorilant) is orally administered without food.
US11058668B2	Methods of treating TTR amyloidosis using AG10 Described herein are methods for treating transthyretin (TTR) amyloidosis in a subject. The methods include specific dosing regimens that have great efficacy in treating the subjects and that are well tolerated in subjects.
US11058667B2	Sacubitril-valsartan dosage regimen for treating heart failure The present invention relates to sacubitril-valsartan dosage regimens for the treatment of heart failure in a patient.
US11058661B2	Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L In various embodiments, the present disclosure provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof having triglyceride levels of about 200 mg/dL to about 499 mg/dL, and hsCRP levels ≥2.0 mg/L.
US11058659B2	Methods and compositions for the treatment of ophalmic diseases and disorders This invention provides compounds, methods and compositions for the treatment of ophthalmic diseases and disorders, including retinal and choroidal disorders and related conditions. More particularly, the invention provides a method of using the provided pharmaceutical compositions for the treatment of ophthalmic diseases and disorders, including retinal and choroidal diseases, and related conditions, upon topical administration to the eye.
US11058656B2	Lipid formulations containing bioactive fatty acids Provided herein is technology relating to lipid compositions containing bioactive fatty acids and particularly, but not exclusively, to compositions containing defined ratios of 5,11,14-eicosatrienoic acid to one or more of: 5,9,12-octadecatrienoic acid; 7,11,14-eicosatrienoic acid; 5,8,11,14-eicosatetraenoic acid; 9,12-octadecadienoic acid; 9-octadecenoic acid; 14-methyl hexadecanoic acid; 11,14 eicosadienoic acid, 5,9-octadecadienoic acid; 5,11-octadecadienoic acid; 9,12,15-octadecatrienoic acid; 5,8,11,14,17-eicosapentaenoic acid; 7,10,13,16,19-docosapentaenoic acid; and 4,7,10,13,16,19-docosahexaenoic acid.
US11058651B2	Topical composition for pain relief A topical composition for nociceptive and neuropathic pain relief comprising one or more of menthol, camphor, methyl sulfonyl methane, lidocaine, Arinica montana, harpagophytum tincture, Emu oil, maqui powder, turmeric oil and in some embodiments methyl salicylate or capsaicin with Cannabis sativa.
US11058649B2	Composition and method for enhancing wound healing The invention relates to a composition for enhancing wound healing and/or for reducing pain and inflammation, comprising a first active ingredient and a second active ingredient, wherein the first active ingredient comprises an antiseptic and the second active ingredient comprises an admixture of at least one vitamin, at least one mineral and at least one amino acid, and to use of the composition for enhancing wound healing.
US11058647B1	Systems, methods, and kits for diagnostics and treatment of viral respiratory infection The present disclosure includes methods, systems, kits and compositions for treating, preventing and diagnosing viral infections, specifically SARS-CoV-2 infections, with an anti-androgen and anti-thyroid medication, a thyroid receptor antagonist, a TGF-β inhibitor or a combination thereof. The present disclosure also describes methods and compositions for the treatment of viral respiratory diseases, specifically SARS-CoV-2 infections, including anti-androgens, anti-thyroid medications, thyroid receptor antagonists, TGF-β inhibitors, RXR inhibitors, furin inhibitors or other agents to disrupt the androgen signaling.
US11058638B2	Tyrosine derivatives and compositions comprising them Provided herein are methods comprising providing a tyrosine derivative and a solid particulate material (and, optionally, melanin) and applying force to said tyrosine derivative and said solid particulate material for a time and under conditions effective to impregnate at least one of said tyrosine derivative and said solid particulate material with the other of said tyrosine derivative and said solid particulate material. The invention also provides compositions comprising at least one of a tyrosine derivative impregnated with a solid particulate material and a solid particulate material impregnated with a tyrosine derivative.
US11058637B1	Surface-modified emulsomes for intranasal delivery of drugs Emulsome compositions comprising phosphatidylcholine, cholesterol, tristearin, and one or more lipophilic bioactive agents such as vinpocetine are provided. The emulsomes may further comprise surface modifications of either [N-(carbonyl-methoxypropylethyleneglycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt] (MPEG-DSPE) for peglyation or stearylamine for cationization. Methods of improving brain delivery of lipophilic bioactive agents by intranasally administering such emulsome compositions are also provided.
US11058636B2	Dispersion process of adapalene in a gel preparation A dispersion process of adapalene gel preparation, including the following steps: pulverizing adapalene raw material to D50 not more than 10 μm and D90 not more than 30 μm by dry detection; adding methyl p-hydroxybenzoate, 1,2-propanediol, carbomer 980 and disodium edetate in water, heating and stirring consistently to obtain a matrix in a uniform jelly; adding poloxamer 188, propylene glycol and ethylene glycol phenyl ether in water, stirring and heating to prepare a mixed solution; adding adapalene in the mixed solution prepared, emulsifying at a high speed, then adding to the matrix for thorough stirring; and then adding a triethanolamine aqueous solution for homogenization and stirring. The preparation prepared has good emulsifying and dispersing effect of adapalene, can be expanded on a large scale, and the industrial promotion prospect is good.
US11058632B2	Drug delivery using aptamer construct A molecular complex comprising a therapeutic agent and a controlled release construct, the controlled release construct comprising a primary matrix conjugation site which is linked to an cell adhesive site, via a binding region and optionally via one or more spacer elements, wherein the binding region has a folded configuration in which it is bound to the therapeutic agent, wherein the construct is configured such that when mechanical tension is applied between the primary matrix conjugation site and the cell adhesive site, the binding region adopts a less folded configuration in which bound therapeutic agent is released. Related controlled release constructs for loading with the therapeutic agent, pharmaceutical compositions and methods of manufacture and use.
US11058630B2	Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines Compositions, devices and methods employing therapeutic concentrations of a triptan for treatment of migraine are described. Also described are methods and apparatuses for delivery of zolmitriptan for achieving a Tmax as quick as 2 minutes and not later than 30 minutes in the majority of subjects.
US11058627B2	Long-wear compositions containing silicone acrylate copolymer and surface-treated pigment Compositions including at least one dendritic silicone acrylate copolymer and at least one surface-treated pigment, as well as methods of making such compositions and methods of applying such compositions to keratinous material are provided.
US11058624B2	Hair care composition comprising cationic polymers and anionic particulates Disclosed is a hair care composition comprising cationic polymers and anionic particulates. The composition of the present invention provides improved deposition of anionic particulates.
US11058620B2	Product composition comprising a discrete particle and an aqueous base composition Disclosed is a product composition comprising: a discrete particle of a mixture composition, wherein the mixture composition comprises a surfactant and a high melting point fatty compound and a benefit agent; and an aqueous base composition comprising a surfactant, a high melting point fatty compound, and an aqueous carrier, and wherein the aqueous base composition is substantially free of detersive surfactant. The product composition of the present invention provides at least one the followings: more flexibility in the product composition rheology; improved stability in the product composition; improved deposition of benefit agents; and improved visual/aesthetic appearance.
US11058618B1	Hair treatment compositions The hair treatment compositions of the instant disclosure typically include about 20 wt. % or more of a polyol; about 5 wt. % to about 50 wt. % of a monoalcohol having a carbon chain of 1 to 10 carbons; about 0.1 to about 5 wt. % of a fatty acid; about 0.1 to about 15 wt. % of a fatty amine; about 0.1 to about 15 wt. % of a fatty alcohol; and about 0.1 to about 15 wt. % of an emollient, wherein all weight percentages are based on the total weight of the hair treatment composition. The hair treatment composition typically has a weight ratio of the amount of polyol to the amount the monoalcohol of 20:1 to 1:1. Additionally, the hair treatment may have a molar ratio of the amount of the fatty acid to the amount of the fatty amine of 0.8:1 to 1.2:1.
US11058617B2	Methods Provided herein are methods of treating one or more symptoms of a gastric disorder in the oral cavity of a subject in need thereof, wherein the method comprises applying to the subject's teeth an oral care composition comprising a basic amino acid in free or salt form, wherein the basic amino acid is arginine (e.g., free form arginine); zinc oxide and zinc citrate; and an orally acceptable carrier.
US11058614B2	Cosmetics concealing wrinkles The present invention relates to a cosmetic composition for concealing wrinkles. The cosmetic composition according to the present invention causes diffuse reflection of light on a wrinkled spot without using powder and effectively fills the wrinkled spot of skin, thereby enabling a temporary concealing of the wrinkle. Because powder is not used, the cosmetic composition has an excellent feeling of use when applied to the skin and prolonged adhesion to the skin, with no white turbidity.
US11058613B2	Suncare compositions A suncare formulation comprising: a dermatologically acceptable organic carrier; a UV radiation absorbing agent; and an SPF booster; wherein the SPF booster comprises a multistage polymeric particle having a core comprising polymerized units of a monoethylenically unsaturated carboxylic acid core monomer and a non-ionic ethylenically unsaturated core monomer; an inner shell comprising polymerized units of a non-ionic ethylenically unsaturated inner shell monomer; a monoethylenically unsaturated carboxylic acid inner shell monomer and an aliphatic inner shell monomer; an outer shell comprising polymerized units of a non-ionic ethylenically unsaturated outer shell monomer; an aliphatic outer shell monomer; a monoethylenically unsaturated non-carboxylic acid outer shell monomer and an ethylenically unsaturated surfactant outer shell monomer; wherein the core, when dry, contains a void; wherein the multistage polymeric particle has an average particle size, when dry, of 50 to 1,000 nm.
US11058611B2	Hydrogen peroxide formulations in barrier layer films with a metallized layer The present disclosure concerns a cosmetic product for modifying the natural color of keratinous fibers, in particular human hair, comprising at least one packaging (VP) and a cosmetic composition (KM) contained in this packaging (VP). The packaging is made of a multi-layer film (F) comprising at least two polymer layers (P1) and (P2) and at least one barrier layer (BS). The cosmetic composition comprises at least one oxidizing agent and at least one thickening agent from the xanthane group. The use of the packaging (VP) in combination with the cosmetic composition (KM) does surprisingly not lead to an inflation of the packaging or an excessive water loss of the agent (KM) during storage.
US11058606B2	Methods and apparatuses for delivering medicaments to intravenous fluid An infusion apparatus including a body having an infusion reservoir and one end of the body adapted to receive a pierceable end of a vial, a barrel rotatably disposed in an opposing end of the body and having an internal fluid chamber, and a plunger received in one end of the barrel, wherein the barrel rotates relative to the body between a first position allowing bi-directional fluid flow between the barrel and the vial, and a second position allowing bi-directional fluid flow between the barrel and the infusion reservoir, and wherein the plunger is movable relative to the barrel to control the bi-directional fluid flow between the barrel and the vial and the bi-directional fluid flow between the barrel and the infusion reservoir.
US11058604B2	Combination emergency wash and faucet unit A combination emergency wash and faucet unit includes a base configured to be coupled to a sink, an emergency wash arm pivotally coupled to the base and including an emergency wash unit configured to dispense a first fluid, and a spout pivotally coupled to the base and configured to dispense a second fluid. The emergency wash arm is repositionable relative to the base between a stored position and an active position. The spout is repositionable relative to the base and the emergency wash arm. The spout is configured to move away from the active position of the emergency wash arm when the emergency wash arm is moved from the stored position toward the active position.
US11058603B2	Mattress system The present invention provides a mattress system (1) devised to achieve a function of automatic detection, mainly comprising: a mattress (2) having a simple structure; a control unit (3) equipped with a unique user interface (31) for caregivers to simultaneously adjust three major functions, namely, therapy mode, therapy intensity and comfort level; and a connection pipe (4) for supplying air and power. The system (1) is further provided with a built-in auto-setting function to sense the body characteristics of the patient (39) lying on the mattress (2) and determine an effective supporting pressure range for the patient (39). By detecting a pressure difference representing the body characteristics of the patient (39) lying on the mattress (2) and comparing with the data stored in a built-in database, the system (1) can always provide the patient (39) with not only a well-proved therapeutic effect through the auto-setting function, but also an adjustable comfort level on the patient's request through the user interface (31).
US11058602B2	Chest compliance directed chest compressions Among other things, in one aspect, we describe a system for assisting with cardiopulmonary resuscitation (CPR). The system includes at least one sensor; and one or more processors configured for calculating a chest compliance relationship based on data received from the at least one sensor, and determining a neutral position of chest compression based at least in part on a feature of the chest compliance relationship. The system can take the form of an active compression-decompression device.
US11058600B1	Stimulation device A stimulation device is provided including a central portion having first and second opposite ends, a first shaft, and a second shaft. The first shaft and the second shaft extend from the first opposite end and the second opposite end, respectively. The central portion may further include one or more stimulation tips that may be integrated with the central portion or may extend from the central portion. The one or more stimulation tips may provide a pleasurable vibrating motion or pulsating sensation to the clitoral region of a female's vagina. The shafts may provide a pleasurable vibrating motion or pulsating sensation to the vagina or anus of a female. Upon insertion of the shafts into each respective female's vagina or anus, the stimulation device may serve to align the vulva or anus of the two females and influence their motion with respect to one another. Accordingly, upon penetration of the vulva or anus, the clitoral region of the first and second female may come in contact with the one or more stimulation tips, facilitating simultaneous stimulation.
US11058598B2	Tilt compensation for tremor cancellation device A method of tremor reduction in a handheld device includes measuring a tremor motion and a tilt motion with a motion tracking module (“MTM”) disposed in a housing of the handheld device. In response to measuring the tremor motion, an attachment arm is moved with at least one motion generating mechanism to reduce the tremor motion in the attachment arm. Additionally, in response to measuring the tilt motion, the attachment arm is moved with the at least one motion generating mechanism to resist the attachment arm hitting a hard stop in the handheld device.
US11058594B2	Systems and methods for repositioning a patient A method and system is provided for repositioning a patient on a transfer surface (e.g., a hospital bed, a stretcher, an imaging system, or the like). The system comprises two rollers positioned on one side of the surface, and a retractable transfer sheet wound around the rollers. The transfer sheet may be unwound from the two rollers to form two layers between the patient and the transfer surface. The patient may then be moved by sliding a top layer of the transfer sheet relative to a second layer of the transfer sheet. After use, the sheet can be retracted around the roller(s), allowing it to be stored in a location that is convenient but out-of-the-way. Such a system may allow a patient to be moved with less force, in less time, with fewer personnel, or with some other benefit.
US11058588B2	Apparatuses and methods for negative pressure wound therapy Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters.
US11058584B2	Methods and systems for OCT guided glaucoma surgery Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured to generate an augmented image by overlaying an OCT image of target location and a graphical visual element identifying the locations, wherein the graphical visual element is registered with the microscope image to aid the surgeon in advancing a distal end of the elongate probe to the target location.
US11058581B2	Adjustable flow glaucoma shunts and methods for making and using same Adjustable flow glaucoma shunts are disclosed herein. In one embodiment, for example, an adjustable flow shunt can include an outflow drainage tube having a proximal inflow region and a distal outflow region. The proximal inflow region can include aperture(s) defining a fluid inlet area positioned to allow fluid to flow therethrough. The shunt further comprises an inflow control assembly at the proximal inflow region. The inflow control assembly can include a control element configured to slidably engage the proximal inflow region and a spring element. The spring element is configured to be activated by non-invasive energy and, upon activation, slidably move the control element along the proximal inflow region such that (a) the one or more apertures are accessible and have a first fluid flow cross-section or (b) the one or more apertures are at least partially covered by the control element and have a second, different fluid-flow cross-section.
US11058579B2	Ophthalmic surgical device for accessing tissue and for performing a capsulotomy A surgical device and procedure are provided for smoothly and easily accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision in the cornea of the eye. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position on the lens capsule. A cutting element mounted to the suction cup is used to cut a portion of the lens capsule and to remove the portion from the eye.
US11058576B2	Method and apparatus for subretinal administration of therapeutic agent An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.
US11058573B2	Heating / cooling body treatment therapy pad system A heating/cooling therapy treatment pad system incorporates a plurality of therapy pads that can be coupled together by connectors and attachments to form an integrated therapy pad assembly. The thermal pads have pouches for receiving thermal inserts that may be heated or chilled. The thermal inserts may be cylindrical in shape and there may be thermal insert gaps, or spaces between the pouches to enable better conformability of the therapy pad to a person's body, such as around the neck. The heating/cooling therapy treatment pad system may include a neck therapy pad, spine therapy pad, head and face therapy pads, shoulder therapy pad, lumbar therapy pad, armpit thermal therapy pad and a thermal therapy pad vest. The system of pads interconnect to provide tailored thermal therapy to multiple areas of a user's body and may be used to effectuate rapid cooling and in particular for those suffering from heat exhaustion.
US11058566B2	Variable rate prosthesis delivery system providing prosthesis alterations Devices, methods, and systems for prosthesis delivery to patient vasculature are provided. A prosthesis delivery device provided herein delivers a prosthesis to the vasculature of a patient and permits an operator to deploy the prosthesis using a single action mechanism to deploy the prosthesis at a standard deployment rate and a dual action mechanism to deploy the prosthesis at an accelerated deployment rate. Deploying the prosthesis at an accelerated deployment rate results in alterations to the deployed prosthesis structure because the prosthesis is deployed with increased axial compression that results in the prosthesis having increased radial force.
US11058561B2	Prosthetic device, system and method for increasing vacuum attachment A prosthetic system includes a prosthetic valve having a valve body with a shaft defining a flow channel fluidly connectable to an interior of a socket. One or more ports in the valve body are in fluid communication with the flow channel and a membrane is positioned in the valve body. A release button associated with the membrane controls allow air flow into the socket via the one or more ports while air can flow out of the socket via the one or more ports independent of operation of the release button. A one-way valve is connected to the valve assembly that selectively permit air flow out of the socket. A valve insert is mountable on the socket and arranged to couple the valve body to the socket. The valve insert defines an opening configured to allow the shaft to extend through the valve insert and into the socket.
US11058557B2	Digital to definitive orthotic and prosthetic device manufacturing system and method Systems and methods for creating custom-fit prosthetic devices, orthotic devices, and related medical devices via three-dimensional printing (3D printing) or additive manufacturing techniques are described. Through the described systems and methods, a residual limb or other body part of a patient is scanned and analyzed to determine measurements and characteristics of the residual limb. The measurements and characteristics of the residual limb are used to design a customized device for the residual limb. The customized device uses multiple different materials. For example, the customized device may use a first material for a frame and a second material for a liner, wherein the first material is more rigid than the second material. The customized device is fabricated using a three-dimensional printer that is capable of printing and bonding multiple different materials at the same time.
US11058556B2	Multimodal abrading device for fusing a sacroiliac joint A multimodal abrading device for preparing a sacroiliac joint (“SI Joint”) to receive a graft implant. The abrading device comprises an abrading head having abrading surfaces on a first pair of opposing sides, the abrading surfaces configured for decorticating the cortical bone of the SI Joint. The abrading head further comprises an open tip having a cutting edge configured to cut bone tissue in the SI Joint. The abrading device further comprises a slide hammer assembly at a proximal end of the abrading device, the slide hammer assembly having a released position that enables operation of the slide hammer assembly, and a locked position that prohibits operation of the slide hammer assembly.
US11058555B2	Holder for an acetabular cup implant The present invention is directed to a system comprising a medical instrument (e.g. cup implant, 3) and a holding device (2) that interacts with said medical instrument to form a sealable cavity within the combined arrangement of components. An impaction device (1) is also provided, preferably which provides means to allow fluid to be expelled from the cavity but which prevents further fluid from entering the cavity.
US11058552B2	Anterior lumbar interbody fusion cage and plate A stand-alone ALIF implant that comprises a cage and a rotatable plate attached to an anterior portion of the cage by a fastener mechanism. The plate may also be integrally formed with the cage, and both are typically manufactured using additive manufacturing techniques. Support material may be added during the additive manufacturing process to lend support to the implant, and may be positioned around the fastener mechanism during manufacturing of the implant. Once formed, the support material may be dissolved away, thereby allowing the plate to rotate independently from the cage, but still remain movably attached via the fastener mechanism. The cage may further comprise webbing thereon to promote bone growth.
US11058546B2	Bone repositioning guide system and procedure An improved surgical system and procedure for correcting a deformity between first and second bones using an alignment guide based on a correction factor. The correction factor can be based on a virtual model of the first and second bones in a deformed configuration and a corrected configuration. In the virtual corrected configuration, first and second virtual axes can be fixed in the respective first and second bones. When reverted to the virtual deformed configuration, the orientation of the first and second axes can be used to determine the correction factor. The alignment guide is used to insert one or more k-wires into each of the first and second bones in a deformed configuration. A correction guide is passed along the k-wires to rotate and/or translate the first bone relative to the second bone into the corrected configuration.
US11058545B2	First metatarsophalangeal joint implant and method for placement An implant is disclosed for the first metatarsophalangeal joint between the proximal phalange and the first metatarsal, the phalange moving in a sagittal plane perpendicular to a transverse plane. The implant includes a metatarsal component for securing against the distal end of the first metatarsal, the metatarsal component having an interfacing surface with a plurality of ridges and valleys. The implant further includes a phalangeal component for securing against the proximal end of the proximal phalange, the phalangeal component having an interfacing surface with a plurality of ridges and valleys, wherein the ridges of the interfacing surface of the metatarsal component are received by the valleys of the interfacing surface of the phalangeal component to provide for a full range of motion in the sagittal plane but impede motion in the transverse plane.
US11058542B1	System and method for joining boney structures Disclosed are system and methods that use at least one non-threaded anchor and an implant with at least one aperture to join boney structures, where the interaction of the head of the anchor with the implant aperture causes the anchor to move transversely with respect to an initial trajectory. This movement causes compression or distraction of the boney structures which are coupled to the anchors.
US11058540B2	Atraumatic adjustment or replacement of a device for treating valve regurgitation An epicardial device for reducing or preventing regurgitation of blood through a valve of a heart includes a main body having a segment adapted to apply force to an epicardial surface of the heart. A member that applies counterforce to the force applied by the segment is also provided. A foundation is configured to be anchored to the epicardial surface of the heart. The foundation includes a surface configured with attachment features. The device further includes a surface configured with mating attachment features configured to attach to the attachment features of the foundation. The mating attachment features and attachment features are separable and reattachable to allow repositioning of at least a portion of the device relative to the foundation.
US11058539B2	Heart valve sealing devices and delivery devices therefor An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the paddle and a moveable arm. The moveable arm has a barbed portion, a first eyelet, and a second eyelet. The hinge portion connects the fixed arm to the moveable arm. A first intermediate suture loop is attached to the first eyelet and a second intermediate suture loop is attached to the second eyelet. At least one actuation suture is attached to the first and second intermediate suture loops.
US11058536B2	Method for replacement of heart valve A method for implanting a replacement heart valve within a diseased valve includes accessing a patient's heart by piercing a myocardium, advancing a guidewire into the patient's heart, and installing an access device in a wall of the heart. The access device preferably has at least one valve mechanism. A valve delivery device is advanced over the guidewire and through the access device. The valve delivery device has a replacement heart valve disposed along a distal end portion thereof. The replacement heart valve preferably includes an outer support structure and a leaflet valve disposed within the outer support structure. The replacement heart valve is radially expanded within the diseased valve. During implantation, the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size having a diameter smaller than the diameter of the diseased valve.
US11058535B2	Replacement mitral valves A prosthetic mitral valve includes an anchor assembly, a strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion. The annular strut frame is disposed radially within the anchor assembly and is attached to the anchor assembly. The central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween.
US11058534B2	Tubular prostheses Tubular prostheses are provided for use in airways, upper digestive, and urinary tracts. Each of these uses has its own specific sets of biological specifications, based on what it must contain and exclude and the physical and chemical pressures and stresses to which it is subjected. The prostheses may be made from allogeneic cells. Thus they can be manufactured and stored prior to an individual's personal need arising.
US11058532B2	Composite scaffold for the repair, reconstruction, and regeneration of soft tissues A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.
US11058531B2	Whipstitched graft construct and method of making the same A whip stitched graft construct and method of formation. The whip stitched graft construct includes a plurality of tendon strand regions or soft tissue grafts placed together so that at least a portion of the plurality of the tendon strand regions are stitched together by employing multiple suture passes placed according to a whip stitching technique. Preferably, the multiple suture passes start at about the mid length of the plurality of tendon strand regions and are advanced toward one of the free ends of the tendon strands. The whip stitched graft construct is provided with at least two regions, one region formed of at least a plurality of tendon strand regions tied and whip stitched together, and the other region formed of untied segments of the plurality of tendon strands.
US11058530B2	Soft tissue grafts, and methods of making and using same Soft tissue grafts, packaged soft tissue grafts, and methods of making and using soft tissue grafts are disclosed. One soft tissue graft includes processed tissue material having first and second opposed surfaces. The first and second opposed surfaces are bounded by first and second edges. The first edge has a concave shape that curves toward the second edge. The second edge has a convex shape that curves away from the first edge. The first surface comprises a plurality of apertures. At least one of the apertures is formed from a multi-directional separation in the first surface. One method of making a soft tissue graft includes positioning a cutting die on a surface of tissue material, pressing the cutting die into the tissue material to cut the tissue material, and processing the cut tissue material to create processed tissue material.
US11058528B2	Urinary incontinence prevention clip for men A urinary incontinence prevention clip for men includes: a clip body having an upper frame positioned so as to correspond to the upper part of male genitalia, a lower frame positioned so as to correspond to the lower part of the male genitalia, and a connection part connected to one side of the upper frame and the lower frame and providing elastic force in a direction, in which the upper frame and the lower frame are spread; cushion parts respectively provided on the inside of the upper frame and the inside of the lower frame; and locking parts formed at both ends of the clip body so as to be fastened to each other, wherein the upper frame is formed so as not to press the blood vessels of the male genitalia and the lower frame is formed so as to press the urethras of the male genitalia.

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