最新美国发明专利第2021-06-08期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US11028396B2	DNA aptamer specifically binding to CFP10, and use thereof The present invention relates to: a DNA aptamer specifically binding to culture filtrate 10 kDa (CFP10); a biosensor for diagnosing tuberculosis, comprising the same: and an information providing method for diagnosing tuberculosis. The present applicants have ascertained that the DNA aptamer, according to the present invention, has the ability to specifically bind to a CFP10 protein and that the binding strength thereof is strong. When the DNA aptamer of the present invention is used, excellent stability superior to that of ELISA methods using existing antibodies can be expected, and thus it is expected that the aptamer can be effectively used in the development of a composition for diagnosing tuberculosis, a biosensor for diagnosing tuberculosis, an information providing method for diagnosing tuberculosis, and the like.
US11028395B2	TNF-alpha-binding aptamer, and therapeutic use for same The present invention relates to a TNF-α-binding RNA aptamer disclosed in SEQ ID NO: 1 or SEQ ID NO: 2, and to the therapeutic use thereof.
US11028390B2	Antisense oligonucleotide controlling expression amount of TDP-43 and use thereof The present invention provides a suppression type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in any of SEQ ID NOs: 2-4, and a promotion type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in SEQ ID NO: 5.
US11028387B2	Double-stranded agents for delivering therapeutic oligonucleotides Disclosed are double-stranded nucleic acid agents that can deliver a therapeutic oligonucleotide within a biological sample, and methods for using the same. In one embodiment, the double-stranded nucleic acid agent comprises a first strand comprising a first RNA region, and a second strand comprising a first DNA region, wherein said first RNA region and said first DNA region are hybridized as a RNA/DNA heteroduplex. Said first strand further comprises a nucleic acid therapeutic oligonucleotide region that is capable of being cleaved from at least one nucleotide in said first RNA region. Methods for using the double-stranded nucleic acid agents include methods for delivering the therapeutic oligonucleotide as a single strand by cleaving it from at least a portion of the first RNA region. The methods further include delivering the double-stranded nucleic acid agent and thus the therapeutic oligonucleotide to a target site within the body of a treatment subject.
US11028385B2	Stable lignocellulolytic enzyme composition The present invention relates to a formulation to stabilize lignocellulolytic enzyme mixture. This invention in particular relates to a formulation composed of lignocellulolytic enzyme with critical dosages of molasses either with petrochemical waste or glycerol as an additive to improve enzyme stability in a synergistic manner.
US11028381B2	CRISPR-associated (Cas) protein A new CRISPR-associated (Cas) protein, termed “CasM,” is described, as well as polynucleotides encoding the same and methods of using CasM for site-specific genome engineering. CasM proteins are capable of targeting and cleaving single-stranded RNA.
US11028380B2	CAS9-CAS9 fusion proteins The present invention provides a Cas9 platform to facilitate single-site nuclease gene editing precision within a human genome. For example, a Cas9 nuclease/DNA-targeting unit (Cas9-DTU) fusion protein precisely delivers a Cas9/sgRNA complex to a specific target site within the genome for subsequent sgRNA-dependent cleavage of an adjacent target sequence. Alternatively, attenuating Cas9 binding using mutations to the a protospacer adjacent motif (PAM) recognition domain makes Cas9 target site recognition dependent on the associated DTU, all while retaining Cas9's sgRNA-mediated DNA cleavage fidelity. Cas9-DTU fusion proteins have improved target site binding precision, greater nuclease activity, and a broader sequence targeting range than standard Cas9 systems. Existing Cas9 or sgRNA variants (e.g., truncated sgRNAs (tru-gRNAs), nickases and FokI fusions) are compatible with these improvements to further reduce off-target cleavage. A robust, broadly applicable strategy is disclosed to impart Cas9 genome-editing systems with the single-genomic-site accuracy needed for safe, effective clinical application.
US11028375B2	Methods for treating anemia in a subject in need thereof In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
US11028373B2	Engineered glucosyltransferases Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.
US11028372B2	Scalable purification method for AAVRH10 A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supernatant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.
US11028371B2	Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same A biological system for generating and preserving a repository of personalized, humanized transplantable cells, tissues, and organs for transplantation, wherein the biological system is biologically active and metabolically active, the biological system having genetically reprogrammed cells, tissues, and organs in a non-human animal for transplantation into a human recipient, wherein the non-human animal does not present one or more surface glycan epitopes and specific sequences from the wild-type swine's SLA is replaced with a synthetic nucleotides based on a human captured reference sequence from a human recipient's HLA.
US11028367B2	Epithelial cell differentiation of human mesenchymal stromal cells The present invention relates to the discovery that different stem cell types (e.g., bone marrow-derived mesenchymal stem cells (BM-MSC) and adipose-derived mesenchymal stem cells (AT-MSC)) undergo large changes in lung epithelial marker expression depending on the substrate on which they are cultured. The present invention includes methods and compositions for differentiating of mesenchymal stem cells, such as bone marrow and adipose tissue mesenchymal stem cells, into lung cells, populations of lung cells, and methods of alleviating or treating a lung defect in a subject in need thereof.
US11028357B2	System for analyzing and sorting of petri dishes A system for analyzing and sorting of petri dishes comprising an analysis tool, a control unit, a first elevator movable along a first elevator axis, a conveyor with a conveyor plane, and at least one carrier built to carry the petri dishes along a carrier axis.The analysis tool is built to assign information to the petri dish, and in case of a first information assigned to the petri dish the control unit is built to move the first elevator into a carrier position, wherein, as soon as the first elevator reaches the carrier position, the control unit is built to move a substantially flat first plate along the first elevator axis from a first neutral position located in the conveyor plane into a first transfer position.
US11028355B2	Methods and systems for efficient bioreactor mixing and light utilization embodying low process energy and scalability Embodiments of the present invention may provide fluid flow coordinators, passive flow field modifiers, or even inwardly protruding helical spines which can be used in continuous, scalable, low energy usage, bioreactor systems perhaps to provide optimal mixing of microorganisms with nutrients, gases, or the like or even to move microorganisms, such as algae, in and out of light for effective and optimal growth.
US11028354B2	Prepared plated media product The present invention relates to systems and methods involving interconnected plate components, including bases, lids and covers, interconnected in a manner such that a continuous strip of each component is prepared. The continuous strips may be stored as rollstock in a reel style. The physical properties of each continuous strip allow the base, lid and/or cover to include means for positive control. In one embodiment, the continuous strip of bases is advanced and processed through an automated system with positive control, and remains in the form of a continuous strip until agar in the bases is cured, at which time the bases are singulated. When a lid is applied to a base using methods described herein, an airtight seal is formed improving the quality of culture media used in testing.
US11028353B2	Method for removing unwanted component included in beverage A method and device for efficiently removing an unwanted component included in a beverage, which includes bringing the beverage into contact with a metal-supported zeolite.
US11028350B2	Powders and granules and process for making such powders and granules Process for making a powder or granule containing at least one chelating agent selected from alkali metal salts of methyl glycine diacetic acid (MGDA) and glutamic acid diacetate (GLDA) and iminodisuccinic acid (IDS), said process comprising the steps of (a) introducing an aqueous solution or aqueous slurry of the respective chelating agent (A) into a spray-dryer or spray-granulator, and removing most of said water by spray-drying or spray granulation using a gas with an inlet temperature of 125 to 250° C., (b) withdrawingpowder or granules, respectively, from the spray-dryer or spray-granulator, respectively, (c) separating off fines from said powder or granules, wherein said fines have a maximum particle diameter of 350 μm, (d) separating off lumps from said powder or granules, wherein said lumps have a particle diameter of 1,500 μm or more, (e) milling said lumps to a maximum particle diameter of 500 μm, (f) re-introducing said fines from step (c) and milled lumps from step (e) into the spray-dryer or spray-granulator, wherein the share of fines is in the range of from 0.5 to 20% by weight of the total chelating agent (A) withdrawn in step (b) and the share of milled lumps is in the range of from 5 to 60% by weight of the total chelating agent (A) withdrawn in step (b).
US11028349B2	Cleansing compositions comprising a mixture of phenol disinfectants Described herein, are personal care compositions comprising an effective amount of an antibacterial component selected from chloroxylenol (PCMX) and o-cymene-5-on (IPMP); phenoxyethanol; piroctone olamine; and a surfactant. Methods of making and using these compositions are also described.
US11028344B2	Composition for aesthetic improvement of food and beverage containers and methods thereof A composition for use in recycled food and beverage containers is disclosed. A mixture of a strong sequestrant, a weak sequestrant, a polymer, an antiscalant and a surfactant is disclosed. Methods directed to using the composition are also disclosed. A composition that cleans and also reduces the defects present on the external surface of containers during a wash cycle is disclosed. The composition may or may not have metallic salts.
US11028338B2	Method for making full use of Lippia origanoides The present invention relates to a method for extracting, separating and purifying compounds of interest obtained from essential oils and plant extracts which is continuously held.
US11028335B2	Grease composition, method for manufacturing grease composition, and method for using grease composition Provided is a grease composition which is excellent in fire extinguishing performance without water and can suppress fuming, malodor, and liquefaction on burning and a method for producing the grease composition.A grease composition contains a base oil (A), a thickener (B), and a fire retardant (C), wherein the base oil (A) contains a base oil (A1) having a 40° C. kinematic viscosity of 300 mm2/s or more, a sulfur content of 20 ppm by mass or less, and an initial boiling point of 400° C. or higher, the fire retardant (C) is at least one of aluminum hydroxide (C1) and 1,3,5-triazine-1,3,5 (2H, 4H, 6H)-tris(ethanol) (C2), and a content of the fire retardant (C) is 1.0 to 12.0 mass % based on a total amount of the grease composition.
US11028333B2	Lubricating oil additives A metal-containing detergent, suitable for use as a lubricant additive, in the form of a concentrate in oil in which a basic metal-containing material is maintained in dispersion or solution in the oil by a gemini surfactant system comprising, or being derivable or derived from, a double bond-unsaturated carboxylic acid having 8 to 30 carbon atoms, the double bond or bonds of which being functionalized to carry polar groups across or on the double bond or bonds and the carboxylic acid group or groups thereof being functionalized to become an amide or ester group carrying at least one alkyl group having 4 to 20 carbon atoms.
US11028331B2	Process for recovering hydrocarbon from hydroprocessed gaseous stream A process for recovery of C5+ hydrocarbons from a stripper gaseous hydroprocessed stream by contacting it with a stripper liquid stream. The stripper liquid stream absorbs C5+ hydrocarbons predominantly over other hydrocarbons thereby increasing C5+ yield and enabling the stripper gaseous stream to meet hydrocarbon limits. The rich absorbent stream may be sent to recovery with the stripper liquid from whence it came.
US11028330B2	Hydrotreatment or hydroconversion process with a stripper and a low pressure separator drum in the fractionation section A facility and a process for hydrotreatment or hydroconversion, in which a fractionation section comprises a stripper which operates on the overhead fraction obtained from a low pressure separator drum.
US11028328B2	Systems and processes for catalytic reforming of a hydrocarbon feed stock Processes for catalytic reforming of a hydrocarbon feedstock may include contacting the hydrocarbon feedstock with catalyst in a first reforming unit to produce a first effluent and used catalyst. The method may further include passing a portion of the first effluent directly to a second reforming unit and contacting the first effluent with catalyst to produce a second effluent and used catalyst. The method may also include passing a portion of the second effluent directly to a third reforming unit and contacting the second effluent with catalyst to produce a reformate effluent and used catalyst. Additionally, the method may include regenerating at least a portion of the used catalyst to produce regenerated catalyst. The catalysts may each include regenerated catalyst.
US11028326B2	Process for hydrotreating a residue stream with hydrogen recycle The subject process enhances catalytic activity for demetallization and desulfurization of a residue feed stream by splitting a recycle hydrogen stream and feeding each of the split hydrogen streams to the first and second stages of demetallation and desulfurization, respectively, with interstage separation. The recycle hydrogen stream may first undergo scrubbing to remove acid gases and compression before recycle. The recycle hydrogen stream is taken from a first hot vapor stream from the first hydrotreating unit and a second hot vapor stream from the second hydrotreating unit.
US11028325B2	Heat removal and recovery in biomass pyrolysis Pyrolysis methods and apparatuses that allow effective heat removal, for example when necessary to achieve a desired throughput or process a desired type of biomass, are disclosed. According to representative methods, the use of a quench medium (e.g., water), either as a primary or a secondary type of heat removal, allows greater control of process temperatures, particularly in the reheater where char, as a solid byproduct of pyrolysis, is combusted. Quench medium may be distributed to one or more locations within the reheater vessel, such as above and/or within a dense phase bed of fluidized particles of a solid heat carrier (e.g., sand) to better control heat removal.
US11028324B2	Flame retardant mixtures, the production and the use thereof The invention relates to a flame retardant mixture comprising99.9999% to 87% by weight of diorganylphosphinic acid salts as component A) and0.0001% to 13% by weight of iron as component B),where the sum total of A) and B) is 100% by weight.The invention likewise relates to processes for producing the aforementioned flame retardant mixture and to the use thereof.
US11028322B2	Composition for washing pickled steel plate, method for washing pickled steel plate by using same, and steel plate obtained thereby A composition for washing a pickled steel plate and a method for washing a pickled steel plate using the same are provided. The composition for washing a pickled steel plate includes a phosphoric acid ester compound, an amine-based compound, sodium carbonate, ammonium acetate, ethylene diamine tetraacetic acid (EDTA) and a remainder of water, and the method for washing a pickled steel plate is performed using the same.
US11028319B2	Passive thermally driven variable opacity materials A variable opacity material is provided that may be in the form of a mixture, such as an emulsion that contains a discontinuous aqueous polymeric solution having an LCST of 0 to 100° C. and a continuous phase containing a hydrophobic polymer, such as a polysiloxane. One or more salts, such as lithium bromide and sodium chloride, may be added to the aqueous solution to lower the LCST of the aqueous solution and to raise the refractive index of the aqueous polymeric solution to substantially match the refractive index of the hydrophobic polymer. The variable opacity materials may be applied in the form of a film to various substrates, such as glass.
US11028314B2	Compositions comprising aminated dextrin compounds and subterranean treatment methods using the same Interactions between aqueous fluids and clay-containing subterranean formations may be problematic due to issues associated with clay destabilization and migration. Subterranean treatment methods may comprise: providing a clay stabilizing composition comprising an amine-functionalized dextrin compound having 2 to about 20 glucose units linked together with α(1,4) glycosidic bonds, and an amine-functionalized dextran polymer having a plurality of glucose units linked together with α(1,6) glycosidic bonds; introducing the clay stabilizing composition into a subterranean formation bearing a clay-containing mineral; and interacting the amine-functionalized dextrin compound and the amine-functionalized dextran polymer with the clay-containing mineral to affect stabilization thereof. A portion of the glucose units are oxidatively opened and functionalized with at least one amine group at a site of oxidative opening in both the amine-functionalized dextrin compound and the amine-functionalized dextran polymer. The amine-functionalized dextrin compound and the amine-functionalized dextran polymer operate synergistically with one another.
US11028313B2	Nanoparticle carrier platform and methods for controlled release of subterranean well treatment additives Nano-sized mixed metal oxide carriers capable of delivering a well treatment additive for a sustained or extended period of time in the environment of use, methods of making the nanoparticles, and uses thereof are described herein. The nanoparticles can have a formula of: A/[Mx1My2Mz3]OnHm where x is 0.03 to 3, y is 0.01 to 0.4, z is 0.01 to 0.4 and n and m are determined by the oxidation states of the other elements, and M1 can be aluminum (Al), gallium (Ga), indium (In), or thallium (Tl). M2 and M3 are not the same and can be a Column 2 metal, Column 14 metal, or a transition metal. A is can be a treatment additive.
US11028311B2	Methods of cementing a wellbore A method of cementing a wellbore comprises combining an alginate suspension additive with a cement slurry to form a cementing composition, the cement slurry comprising an aqueous carrier and a cementitious component; injecting the cementing composition into the wellbore; and allowing the cement composition to set.
US11028305B2	Delayed breaker composition A downhole fluid composition having a saccharide gelling agent, an oxidative breaker, and a sequestering agent. The sequestering agent is hydrocarbon miscible and inert to oxidation by the oxidative breaker. The sequestering agent sequesters the oxidative breaker or an activator for the oxidative breaker, whereby oxidation of the gelling agent is inhibited. The downhole fluid may also include a proppant. Upon contacting hydrocarbons downhole or reaching a predetermined temperature, the sequestering agent releases the oxidative breaker or activator thereby oxidizing the saccharide gelling agent.
US11028302B2	Cold storage medium Provided is a cold storage medium according to the present invention contains tetra-n-butylammonium ions, silver ions, at least one kind of halide ions selected from the group consisting of fluoride ions, chloride ions, and bromide ions, water, and at least one kind of carboxylic acid ions each represented by the following chemical formula R—COO− (where R represents a hydrocarbon group).
US11028301B2	Temperature regulating polyurethane gels A method for the production of a temperature regulating polyurethane gel composition and corresponding articles includes fatty acid esters as a phase change material (PCM) directly incorporated in the fluid phase of a polyurethane gel without encapsulation. The liquid or melted PCM is solved in the polyol component of the gel and is able to crystallize and melt within the gel structure reversibly. The polyurethane gels are under-crosslinked and include an at least nominal three functional ethylene oxide-comprising alkylene oxide polyether polyol with 0 to 40% EO and an isocyanate with an effective functionality of from 1.5 to 3.5. The gels are useful in articles where the gel can be positioned close to the human body for temperature regulating purposes, and especially to improve the sleeping comfort of a resting person.
US11028300B1	Environmentally friendly refrigerant compositions A refrigerant composition includes R125 (pentafluoroethane), R134a (1,1,1,2-tetrafluoroethane), R600a (isobutane) and a polyol ester (POE) lubricant. In one exemplary embodiment, the refrigerant includes about 53-57 wt % R125, about 40-44 wt % R134a, about 1-5 wt % R600a and no more than about 1 wt % POE. In another embodiment, the refrigerant composition includes about 54-56% R125, about 41-43 wt % R134a, about 2-4% R600a and about 0.3-0.7 wt % POE. In yet another embodiment, the refrigerant composition includes about 54.63 wt % R125, about 41.72 wt % R134a, about 2.98 wt % R600a and about 0.67 wt % POE. Manufacturing the refrigerant composition includes charging a vessel with about 53-57 wt % R125, about 44 wt % R134a, about 1-5 wt % R600a to form as 100 wt % charge, and then injecting no more than about 1 wt % POE.
US11028290B2	Heat-applied gap finishing tape A gap finishing tape for use with drywall applications includes a trim strip body extending along a central body axis, a hot melt adhesive extending along the central body axis, and a backing paper. The trim strip body includes a first surface, a second surface opposite the first surface, a first side, and a second side opposite the first side, and is at least partially constructed from a metallic material. The backing paper is at least partially secured to the second surface of the trim strip body. The trim strip body is at least partially embedded in the hot melt adhesive.
US11028285B2	Urethane (meth)acrylate and active energy ray-curable resin composition Provided is a compound capable of forming a coating layer that has excellent scratch resistance and still has stain resistance (in particular, stain resistance against hair dyes) and workability (impact resistance) both at satisfactory levels.The urethane (meth)acrylate has a cyclic structure in a molecule. The urethane (meth)acrylate has a total weight of carbon, oxygen, nitrogen, and sulfur atoms constituting the ring or rings of the cyclic structure of 10 percent by weight or more based on the total amount (100 percent by weight) of the urethane (meth)acrylate. The urethane (meth)acrylate also has an average number of functional groups of 3.5 to 4.5.
US11028282B2	Process for bonding hydrophobic surfaces having cationic guar-containing primer coating thereon The instant invention relates to primary coating compositions that comprises a cationic polysaccharide, to be applied on a hydrophobic surface before a subsequent application of a polar or water based coating composition, such a as a paint or an adhesive.
US11028276B2	Surface-treated metal sheet, coated member, and method for producing coated member Provided are a surface-treated metal sheet excellent in the adhesiveness to a coating treatment film and weldability and a coated member. The surface-treated metal sheet includes a metal sheet and a coating film placed on at least one major surface of the metal sheet; the coating film contains oxide particles, a binder resin, and electrically conductive particles; the amount of electrically conductive particles contained is 5 to 30 mass % relative to the coating film; the oxide particles include non-doped oxide particles and/or doped oxide particles; the non-doped oxide particles include at least one kind selected from the group consisting of zinc oxide particles, tin oxide particles, magnesium oxide particles, calcium oxide particles, and strontium oxide particles; the doped oxide particles include at least one kind selected from the group consisting of doped zinc oxide particles and doped tin oxide particles; the amount of oxide particles contained is 1 to 30 mass %, but is 1 to 10 mass % relative to the coating film in the case of not including doped oxide particles; and the amount of the coating film attached to the major surface is 2 to 20 g/m2.
US11028274B2	Method for preventing hardener compounds to be formed from hardener precursors and extending shelf life of the dispersion A method is disclosed for preventing hardener compounds to be formed from hardener precursors in a sealed and pressurized aerosol can. This includes a paint forming dispersion containing after sealing the can a liquefied propellant, epoxy or/and polyurethane resins amount W1, hardener precursor of the epoxy or/and polyurethane resins amount W3, where the epoxy or urethane hardener precursors are selected from a group including an imine, an enamine, a Mannich base, a Schiff's base, an oxazolidine, an aldimine and mixtures thereof, free water of amount W1 in a range of 1-10000 ppm, and brought into the can alongside with the other paint dispersion forming chemicals before sealing the can. A catalytic compound prevents formation of the epoxy or/and polyurethane hardener amines from the epoxy or/and polyurethane hardener precursors:
US11028272B2	Glitter pigment, pigment-containing composition, and pigment-containing painted product The present invention provides a new glitter pigment suitable for providing high-brightness whitish reflected light. The glitter pigment according to the present invention includes: a flaky substrate 1; and a silicon oxide layer 2 and a titanium oxide layer 3 formed in this order on the flaky substrate 1, wherein in the case where the flaky substrate is the glass flake, the glass flake has a thickness of 284 to 322 nm, the silicon oxide layer has a thickness of 89 to 109 nm, and the titanium oxide layer has a thickness of 51 to 86 nm. In the case where the flaky substrate is the alumina flake, the alumina flake has a thickness of 260 to 280 nm, the silicon oxide layer has a thickness of 79 to 102 nm, and the titanium oxide layer has a thickness of 47 to 87 nm.
US11028270B2	Black matrix composition, black matrix, and black matrix production method [Problem] To provide a composition for a black matrix which is a material suitable for manufacturing a black matrix, which is suitable for a high luminance display device structure and has high heat resistance and high light-shielding properties.[Means for Solution] The present invention uses a composition for a black matrix comprising: (I) a black colorant containing carbon black having a volume average particle diameter of 1 to 300 nm; (II) a siloxane polymer to be obtained by hydrolyzing and condensing a silane compound represented by a prescribed formula in the presence of an acidic or basic catalyst; (III) surface modified silica fine particles; (IV) a thermal base generator; and (V) a solvent.
US11028261B2	Separator, mechanical element, operation guide device and manufacturing apparatus Provided is a separator having excellent chemical resistance, impact resistance, and productivity. A bearing retainer (1) is a separator that is interposed between two spheres adjacent to and moving in conjunction with each other for retaining the spheres configured to be movable in conjunction with and apart from each other and is formed from a resin composition containing a fluororesin which is a polymer of a monomer containing vinylidene fluoride as a main component. The bending modulus of elasticity of the resin composition is 1600 MPa or less, and the Charpy impact strength of the resin composition is 26 kJ/m2 or more.
US11028260B2	Rubber composition, rubber molded body, and method for production of rubber molded body A rubber composition contains: (A) an ethylene-α-olefin-based copolymer rubber including an ethylene unit and an α-olefin unit having 3 or more carbon atoms; (B) a fire retardant including a phosphorus atom and a nitrogen atom; (C) a thermally expandable graphite; and (D) additive particles that are porous particles or particles having ion exchangeability. A content of the fire retardant is 50 to 250 parts by mass and a content of the additive particles is 15 parts by mass or less with respect to 100 parts by mass of the ethylene-α-olefin-based copolymer rubber.
US11028258B2	Metallocene catalyst system for producing LLDPE copolymers with tear resistance and low haze Ethylene polymers having a density from 0.908 to 0.925 g/cm3, a melt index from 0.5 to 3 g/10 min, a ratio of Mw/Mn from 2 to 4, a ratio of Mz/Mw from 1.6 to 2.3, a CY-a parameter from 0.45 to 0.6, and an ATREF profile characterized by a single peak at a peak ATREF temperature from 76 to 88° C., and by less than 4.5 wt. % of the polymer eluting above a temperature of 91° C. These ethylene polymers can be used to produce various articles of manufacture, such as blown and cast films with a beneficial combination of high tear resistance and low haze.
US11028253B2	Resin composition and resin molded article Provided is a resin composition containing: cellulose acylate (A); at least a polymer (B) selected from a group consisting of: a polymer (b1) having a core-shell structure including a core layer containing a butadiene polymer, and a shell layer located on an surface of the core layer and containing a polymer selected from a styrene polymer and an acrylonitrile-styrene polymer; a styrene-ethylene-butadiene-styrene copolymer (b2); polyurethane (b3); and aromatic polyester (b4); and a plasticizer (C). A resin molded article obtained by molding the resin composition satisfies at least one of the following conditions (1) and (2): (1) a heat distortion temperature measured in accordance with an ASTM D648-07 B method is 95° C. or less; and (2) a heat distortion temperature measured in accordance with an ISO 75-2 A method (2013) is 80° C. or less.
US11028250B2	Composition with thermal conductivity and laser plating performance by core-shell structure LDS additive with metal compounds coated on mineral filler surface The disclosure concerns thermally conductive polymer compositions comprising: (a) from about 20 wt % to about 80 wt % of at least one polymer component; (b) from greater than about 0 wt % to about 70 wt % of a thermally conductive filler; and (c) from about 0.1 wt % to about 40 wt % of a laser activatable additive having a core-shell structure; wherein the core comprises an inorganic filler and the shell comprises a laser activatable component; wherein the combined weight percent value of all components does not exceed about 100 wt %; wherein all weight percent values are based on the total weight of the composition; and wherein a molded sample of the blended thermoplastic composition has a through plane thermal conductivity of at least about 0.40 W/m·K when determined in accordance with ASTM E1461.
US11028248B2	System and process for recycling contaminated polyolefins The invention relates to a recycling process for contaminated polyolefins, in particular HDPE, wherein the contaminated polyolefin is swelled using a solvent such that contaminants in the polyolefin dissolve in the solvent, and the solvent as well as the contaminants dissolved from the solvent are removed from the polyolefin.
US11028245B2	Porous air permeable polytetrafluoroethylene composites with improved mechanical and thermal properties Porous air permeable expanded PTFE composite with enhanced mechanical and thermal properties are described. The node and fibril microstructure of expanded PTFE is coated on and within the node and fibril microstructure with a suitably chosen polymer to impart property enhancement while maintaining porosity. The coating polymer content of the composite is maintained between 3 and 25 weight percent of the composite and the areal mass of the composite is less than 75 gm/m2. Exemplary enhancement to properties may include, among others, Average Tensile Strength (ATS) (in MPa)×Z strength (in MPa) of 50 MPa2 or greater, preferably 100 MPa2 or greater, with air flow less than 500 Gurley seconds. Coating polymers with appropriate temperature resistance provides composites which further exhibit shrinkage of less than 10% at temperatures up to 300° C. with air flow of less than 500 Gurley seconds.
US11028242B2	Modified silicon particles for silicon-carbon composite electrodes Methods of forming a composite material film can include providing a mixture comprising a precursor and silane-treated silicon particles. The methods can also include pyrolysing the mixture to convert the precursor into one or more carbon phases to form the composite material film with the silicon particles distributed throughout the composite material film.
US11028240B2	Composite materials with desired characteristics A type of composite material where the matrix material and additive are held together by covalently or non-covalently bound ligands is described. A particularly useful composite material covered by the present invention is a carbon nanotube-reinforced composite material where the matrix consists of a polymer, covalently attached to a linker, where said linker is non-covalently attached to the carbon nanotube. Methods for the preparation of such composite materials are provided.
US11028236B2	Method for processing dandelion plant components The invention relates to a method for processing dandelion plant components, particularly dandelion plant components of the Taraxacum kok-saghyz variety, in which, according to the method, rubber is obtained as a first valuable product, said method being characterised by the following steps: A) grinding and/or squeezing the dandelion plant components, preferably while adding water to form a pulp; and B) first separation of the pulp into at least one phase 80 which is high in inulin and low in rubber and at least one phase 90 which is high in rubber and low in inulin, the phase 90 which is high in rubber and low in inulin forming the first valuable product or the first valuable product being obtained from the phase which is high in rubber and low in inulin.
US11028232B2	Process for preparing siloxanes containing oxamido ester groups Oximido ester-functional siloxanes, including those with oxamido ester side chains, are produced by reacting an alkoxy oxamido ester silane with water, optionally in the presence of further alkoxy silanes.
US11028231B2	Polysiloxane comprising substituents having multiple aryl groups A polysiloxane comprising: (a) from 40 to 90 mole % units of formula R1R2SiO2/2, (b) from 10 to 60 mole % units of formula R3SiO3/2, and (c) from 0 to 5 mole % units of formula R1R4SiO2/2; wherein R1 and R2 independently are phenyl or C1-C6 alkyl; R3 represents at least one C1-C30 hydrocarbyl group; R4 is —Ar1-X—Ar2, where Ar1 and Ar2 independently are C6-C12 aryl and X is O CH2; provided that the polysiloxane comprises at least one —Ar1-X—Ar2 group.
US11028227B2	Poly(amide-imide) copolymer, composition for preparing poly(amide-imide) copolymer, article including poly(amide-imide) copolymer, and display device including the article A poly(amide-imide) copolymer that is a reaction product of a substituted or unsubstituted linear aliphatic diamine including two terminals, a diamine represented by Chemical Formula 1, a dicarbonyl compound represented by Chemical Formula 2, and a tetracarboxylic acid dianhydride represented by Chemical Formula 3: wherein, in Chemical Formulae 1 to 3, A, R3, R10, R12, R13, X, n7 and n8 are the same as defined in the specification.
US11028226B2	Heat resistant polyimide film and preparation method thereof A high temperature resistant polyimide film and its preparation method. The present invention relates to a polyimide film and its preparation method and solves the problems of honeycomb's and skin panel's core adhesive—polyimide film with insufficient heat resistance, no climbing of bonding core structure and adhesive fillet formation. The high temperature resistant polyimide film is made by polyimide solution, inorganic filler modifier and interface coupling agent by the steps of: under specific temperature and stirring conditions, adding inorganic filler modifier and interface coupling agent to polyimide solution, stirring to obtain the adhesive agent; filtering and degassing the adhesive agent, casting to a stainless steel drum with carrier cloth and release paper to obtain a self-supporting film; then heating and annealing to obtain the final polyimide film. The present invention is applied to high temperature resistant polyimide film and its preparation method.
US11028225B2	Monomer mixture and curable composition containing same Provided is a monomer mixture that is rapidly cured to form a cured product having high hardness, excellent alkali resistance, and excellent adhesion to a substrate. The monomer mixture of the present invention is a monomer mixture containing at least: a compound represented by Formulas (a-1) and/or (a-2); a compound (2B) including two cationically polymerizable groups per molecule, at least one of the cationically polymerizable groups being an epoxy group; a compound (3B) including three or more cationically polymerizable groups per molecule, at least one of the cationically polymerizable groups being an epoxy group; and a compound represented by Formula (c-1).
US11028221B2	PET polymer with an anti-crystallization comonomer that can be bio-sourced A polyethylene terephthalate (PET) polymer having diacid units derived from diacid compounds, said diacid units comprising: a) from 92.50 mol % to 97.75 mol % of terephthalic units derived from terephthalic acid (TA) or an ester thereof, and b) from 2.25 mol % to 7.50 mol % of 2,5-FDCA units derived from 2,5- furandicarboxylic acid (2,5-FDCA) or an ester thereof, and-diol units derived from diol compound(s), the diol units having monoethylene glycol units derived from monoethylene glycol (MEG), as well as to a method to prepare a PET polymer. The use of a 2,5-FDCA compound selected from 2,5- furandicarboxylic acid (2,5-FDCA) and esters thereof as an anti-crystallization comonomer in a PET polymer and a bio-based PET polymer in which the anti-crystallisation comonomer is bio-based.
US11028216B2	Polycarbodiimide copolymer To provide a polycarbodiimide copolymer and a modified polycarbodiimide copolymer each suitable for a curing agent that can allow a cured product of a carboxy group-containing resin composition to be improved in flexibility without any loss of water resistance, as well as a curing agent of a carboxy group-containing resin composition, and a carboxy group-containing resin composition. The present invention enables a cured product to be enhanced in water resistance due to introduction of a predetermined soft segment into a polycarbodiimide molecule, in use for a curing agent, and also enables a carboxy group-containing resin composition to be enhanced in storage stability due to modification with an aliphatic amine or an aromatic heterocyclic amine.
US11028213B2	Production of dispersants by nitroxide-mediated solution polymerization The present invention relates to processes for preparing a copolymer, especially a dispersant for solid particles, in particular a dispersant for mineral binder compositions, wherein ionizable monomers m1 and side chain-bearing monomers m2 are polymerized by nitroxide-mediated solution polymerization to give a copolymer, wherein the polymerization is conducted in the presence of an agent comprising a carboxyl group-bearing and phosphated alkoxy amine.
US11028210B2	Core-shell flow improver A flow improver comprising a plurality of core-shell particles that can be formed by emulsion polymerization. The core of the core-shell particles can include a drag reducing polymer, while the shell of the particles can include repeat units of a hydrophobic compound and an amphiphilic compound. The flow improver can demonstrate increased pumping stability over conventionally prepared latex flow improvers.
US11028206B2	Polymerizable composition for optical articles A polymerizable composition includes the reaction product of an isohexide bischloroformate, at least one polyol, allyl alcohol, and, optionally, at least one polychloroformate. An exemplary polymerizable composition includes (a) the transesterification reaction product of an isohexide, diallyl carbonate, and at least one polyol; and (b) organic peroxide. A polymerizate including the polymerizable composition and an optical article including the polymerizable composition are also provided.
US11028203B2	Molecular imprinted polymers targeting phenylalanine Disclosed is agents and methods that target metabolism malfunctions, inborne as well as acquired, as well as methods for preparation of the agents. In particular, the invention relates to methods for preparing molecular imprinted polymers with high binding capacity for phenylalanine or tyrosine, MIPs that bind phenylalanine or tyrosine, and methods for treating phenylketonuria, alkaptonuria, and hypertyrosinemia.
US11028199B2	Fluoropolymer powder and method for producing same The invention provides a powder that is easily redispersible in a liquid medium such as water. The powder contains a fluoropolymer. The fluoropolymer contains at least one group A selected from the group consisting of —SO2Y, —COOR, —SO3X, —SO2NR12, and —COOX, wherein Y is a halogen atom; R is a C1-C4 alkyl group; X is M1/L or NR14, where M is a hydrogen atom or an L-valent metal, the L-valent metal being a metal in group 1, group 2, group 4, group 8, group 11, group 12, or group 13 of the periodic table; and R1s are each individually a hydrogen atom or a C1-C4 alkyl group. The powder exhibits a dispersion of 50% or higher. The dispersion is calculated by filtering a composition obtainable by mixing the powder with water through a mesh having an opening of 20 μm.
US11028198B2	Tetrafluoroethylene and perfluorinated allyl ether copolymers A copolymer having tetrafluoroethylene units and second polymerized monomer units in a range from 0.2 to 1 percent by weight, based on the total weight of the copolymer. Rf is a linear or branched perfluoroalkyl group having from 1 to 8 carbon atoms and optionally interrupted by one or more —O— groups, n is independently from 1 to 6, and z is 0, 1, or 2. The copolymer has a melt flow index in a range from 0.02 grams per 10 minutes to 19.4 grams per 10 minutes. The copolymer can be extruded to make articles, such as insulated cables. A method of making the copolymer is also disclosed.
US11028197B2	Processes to produce poly alpha-olefin trimer and apparatus therefor In at least one embodiment, a process to produce a poly alpha-olefin (PAO) includes introducing a first alpha-olefin to a first catalyst system comprising activator and a metallocene compound into a continuous stirred tank reactor or a continuous tubular reactor under first reactor conditions to form a first reactor effluent. The first alpha-olefin is introduced to the reactor at a flow rate of about 100 g/hr or more. The first reactor effluent includes at least 60 wt % of PAO dimer and 40 wt % or less of higher oligomers, where the higher oligomers are oligomers that have a degree of polymerization of 3 or more. The process includes introducing the first reactor effluent and a second alpha-olefin to a second catalyst composition including an acid catalyst in a second reactor to form a second reactor effluent comprising PAO trimer.
US11028196B2	Polyolefin compositions A composition comprising vinyl-terminated polyethylene having an Mn from about 200 g/mol to about 10,000 g/mol; and a comb polyolefin having polyethylene arms attached to a random copolymer backbone, said backbone including units derived from an alpha-olefin having 3 or more carbon atoms, where the polyethylene arms have an Mn from about 200 g/mol to about 10,000 g/mol, and where the comb polyolefin has an Mp from about 7,500 to about 400,000 g/mol.
US11028191B2	Polymerization catalysts with improved ethylene enchainment Embodiments of the present disclosure directed towards polymerization catalysts having improved ethylene enchainment. As an example, the present disclosure provides a polymerization catalyst having improved ethylene enchainment, the polymerization catalyst comprising a zirconocene catalyst of Formula (I) where R1 is a C1 to C20 alkyl, aryl or aralkyl group, wherein R2 is an C1 to C20 alkyl, aryl or aralkyl group, and where R3 is a C1 to C20 alkyl or a hydrogen, and where each X is independently a halide, C1 to C20 alkyl, aralkyl group or hydrogen.
US11028188B2	Processes for recovering rubber from aged briquettes Provided herein are organic solvent-based processes for the removal of rubber from aged briquettes made from compressed plant matter (briquettes) of non-Hevea plants.
US11028186B2	Cellulose derivative, cellulose resin composition, molded body and product using same A cellulose derivative obtained by substituting at least part of hydrogen atoms of hydroxy groups of a cellulose with an acyl group having 2 to 4 carbon atoms, a long-chain organic group having 7 or more carbon atoms and a high refractive-index organic group.
US11028168B2	Use of a CD6 binding partner and method based thereon The present disclosure relates to methods for treatment and prevention of disease conditions mediated by T-helper 17 (Th17) and/or T-helper 1 (Th1) T lymphocytes (T cells). In particular, the present disclosure relates to use of anti-CD6 antibody for treatment of disease conditions mediated by auto-reactive Th17 and Th1 T lymphocytes. The methods of the present disclosure further have utility in methods for modulating an immune response by suppressing production of the cytokine IL-23R, thereby decreasing inflammation mediated by Th17 cells.
US11028167B1	Anti-SARS-Cov-2 antibodies derived from 3bgf This disclosure provides antibodies and antigen-binding fragments that are derived from 3bgf and that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments herein can be used to diagnose a SARS CoV-2 infection.
US11028165B2	Nucleic acid encoding anti-GM-CSF antibodies The present invention provides recombinant antigen-binding regions, antibodies and functional fragments thereof that are specific for GM-CSF, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, inflammatory diseases such as rheumatoid arthritis. Antibodies of the invention also can be used in the diagnostics field, as well as for further investigating the role of GM-CSF in the progression of various disorders. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use.
US11028163B2	Heavy chain only antibodies to PDGF Disclosed herein are monospecific HCAb antibodies with antigen-binding specificity to PDGF and bispecific antibodies with antigen-binding specificities to PDGF-2 and VEGF or to PDGF and ANG-2.
US11028162B2	Methods for manufacturing activatable binding polypeptides comprising matrix metalloprotease cleavable moieties Activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM) are provided. Activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM are provided. Furthermore, ABPs which contain a first TBM, a second TBM and a CM are provided. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. Further provided are libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. Further provided are ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use.
US11028160B2	Treating refractory migraine Disclosed herein are methods of treating or reducing incidence of migraine and/or at least one secondary symptom associated with refractory migraine in a subject having refractory migraine comprising administering to the subject a monoclonal antibody that modulates the CGRP pathway. Compositions for use in the disclosed methods are also provided. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
US11028157B2	Binding molecules that specifically bind to tau The invention relates to binding molecules and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The invention also relates to diagnostic, prophylactic and therapeutic methods using the binding molecules or antigen-binding fragments.
US11028155B2	Enhanced delivery of drugs to the brain Compositions and methods related to antibodies or antibody fragments which are capable of crossing the blood brain barrier are provided.
US11028149B2	Recombinant polypeptide production method Provided is a method capable of producing a protein at a high level using a cultured animal cell, comprising culturing a cell that expresses APES (Antibody Production Enhancing Sequence) and into which a DNA encoding a desired polypeptide has been introduced, thereby producing the desired polypeptide. APES contains a nucleotide sequence related to nuclear factor κB inhibitor α (NfkBia) and has a function of decreasing the intracellular expression of NfkBia.
US11028148B2	Recombinant collagen and elastin molecules and uses thereof This disclosure provides non-naturally occurring collagen and elastin molecules. The non-naturally occurring collagens and elastins include truncated collagens, truncated elastins, as well as fusion proteins thereof. The non-naturally occurring collagen and elastin are useful in foods, cosmetics and many other products and uses.
US11028147B2	Hydrolyzed collagen compositions and methods of making thereof Disclosed herein are hydrolyzed collagen compositions. The compositions are inexpensive to make and can be produced without the use of proteolytic enzymes, decolorizing agents, antibacterial and antifungal agents, and the like. Further, the compositions are substantially free of odors and are white to light yellow in color and are suitable to be used as dietary supplements. Also disclosed are methods for producing the compositions.
US11028143B2	Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules The invention provides T cells comprising nucleic acid sequence encoding a chimeric antigen receptor and a nucleic acid sequence encoding an enhancer of T cell priming, compositions including the T cells, and methods of using the T cells to treat diseases associated with the expression of disease-associated antigens.
US11028135B2	Lactobacillus acidophilus surface layer protein a (SlpA) as a therapeutic agent for the treatment of inflammatory diseases The current invention provides a recombinant bacterium, the recombinant bacterium being genetically modified to decrease or eliminate the display of lipoteichoic acid (LTA), surface layer protein B (SlpB) and surface layer protein X (SlpX) on the surface of said bacterium. Efficacious therapies for a subject suffering from an inflammation mediated disease are also provided. The methods of the current invention comprise administering to a subject in need thereof a therapeutically effective amount of the recombinant L. acidophilus cells or a therapeutically effective amount of the isolated surface layer protein A (SlpA) or a non-naturally occurring derivative thereof. The recombinant L. acidophilus cells or SlpA isolated from L. acidophilus can be in a pharmaceutical composition comprising a pharmaceutically acceptable carrier and/or excipient. In an embodiment of the invention, the pharmaceutical composition is administered orally.
US11028130B2	PR13.5 promoter for robust T-cell and antibody responses The invention encompasses recombinant poxviruses, preferably modified Vaccinia Ankara (MVA) viruses, comprising a Pr13.5 promoter operably linked to a nucleotide sequence encoding an antigen and uses thereof. The invention is drawn to compositions and methods for the induction of strong CD8 T cell and antibody responses to a specific antigen(s) by administering one or more immunizations of the recombinant MVA to a mammal, preferably a human.
US11028129B2	Compositions for expanding regulatory T cells (Treg) populations, and treating and ameliorating autoimmune diseases and conditions In alternative embodiments, provided are compositions, including e.g., isolated, synthetic or recombinant peptides or polypeptides, for: expanding regulatory T cells (Treg) populations; or, for treating, ameliorating, preventing or reversing a vascular inflammation, and Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries, including vascular coronary abnormalities and the same or similar types of acute or chronic vascular inflammatory abnormalities, and methods for making and using them. In one embodiment, provided are immunotherapies for promoting expansion of natural, regulatory T cells to establish, or re-establish, vascular homeostasis; or, for treating, reversing, preventing or ameliorating: a disease or condition associated with an autoimmune disease or condition; an immune-mediated vascular disorder; a disease or condition that is currently treated with intravenous immunoglobulin (WIG) therapy; a vascular coronary abnormality; an acute or a chronic vasculitis; an autoimmune inflammatory vasculitis; a T cell mediated pediatric vasculitis; Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries; atherosclerosis; rheumatoid arthritis or Juvenile Idiopathic Arthritis; an autoimmune disease or condition; or, a neoplastic hematological disorder such as a lymphoma (e.g., a T cell lymphoma) or a leukemia.
US11028127B2	Peptides capable of reactivating p53 mutants The invention provides peptides that can reactivate p53 mutants efficiently and specifically, as well as methods that allow the identification, selection and isolation of such peptides, in a precise, cost and time effective manner. In particular, there are provided mutant p53 reactivating peptides that can restore the native wild type p53 folding, and hence the tumor suppressor activity, to the mutant p53 protein. Such peptides are useful for treating various conditions and diseases in which p53 is mutated.
US11028125B2	Methods for extracting proteins from a blood-based material Methods of producing multiple protein products from blood-based materials including alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins are described herein. The inventive methods include steps of: salt fractionation, chromatography, ultrafiltration, diafiltration, solvent-detergent treatment, and sterile filtration. Advantageously, the inventive methods are simple and produce alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins in high yields. The sequence of process steps can be selected to obtain multiple products from various in-process materials, such as supernatants, pastes, chromatography flow-though, and chromatography washes.
US11028123B2	Capping of unprotected amino groups during peptide synthesis The present invention relates to a method for the synthesis of a polypeptide comprising a pre-determined amino acid sequence. The method according to the invention comprises coupling cycles of coupling an N-terminally protected amino acid building block C-terminally at an unprotected N-terminal amino group of an amino acid chain, wherein at least one coupling cycle comprises a coupling step (a), a capping step (b), and a de-protecting step (c).
US11028122B1	Antisense nucleic acids The present invention provides an oligomer which efficiently enables to cause skipping of the 53rd exon in the human dystrophin gene. Also provided is a pharmaceutical composition which causes skipping of the 53rd exon in the human dystrophin gene with a high efficiency.
US11028118B2	Efficient synthesis of nicotinamide mononucleotide The invention provides a process for the preparation of nicotinamide mononucleotide having formula (I): The method involves the protection of nicotinamide riboside by ketalization, followed by phosphorylation and then deprotection to provide nicotinamide mononucleotide.
US11028116B2	Labelled nucleotides The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
US11028114B2	Amphotericin B derivatives with improved therapeutic index Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3′ or C4′ modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.
US11028110B2	Process for the alkoxycarbonylation of alcohols The invention relates to a process comprising the following process steps: a) introducing a first alcohol, the first alcohol having 2 to 30 carbon atoms; b) adding a phosphine ligand and a compound which comprises Pd, or adding a complex comprising Pd and a phosphine ligand; c) adding a second alcohol; d) supplying CO; e) heating the reaction mixture, the first alcohol reacting with CO and the second alcohol to form an ester; where the phosphine ligand is a compound of formula (I) where m and n are each independently 0 or 1; R1, R2, R3, R4 are each independently selected from —(C1-C12)-alkyl, —(C3-C12)-cycloalkyl, —(C3-C12)-heterocycloalkyl, —(C6-C20)-aryl, —(C3-C20)-heteroaryl; at least one of the R1, R2, R3, R4 radicals is a —(C3-C20)-heteroaryl radical; and R1, R2, R3, R4, if they are —(C1-C12)-alkyl, —(C3-C12)-cycloalkyl, —(C3-C12)-heterocycloalkyl, —(C6-C20)-aryl or —(C3-C20)-heteroaryl, may each independently be substituted by one or more substituents selected from —(C1-C12)-alkyl, —(C3-C12)-cycloalkyl, —(C3-C12)-heterocycloalkyl, —O—(C1-C12)-alkyl, —O—(C1-C12)-alkyl-(C6-C20)-aryl, —O—(C3-C12)-cycloalkyl, —S—(C1-C12)-alkyl, —S—(C3-C12)-cycloalkyl, —COO—(C1-C12)-alkyl, —COO—(C3-C12)-cycloalkyl, —CONH—(C1-C12)-alkyl, —CONH—(C3-C12)-cycloalkyl, —CO—(C1-C12)-alkyl, —CO—(C3-C12)-cycloalkyl, —N—[(C1-C12)-alkyl]2, —(C6-C20)-aryl, —(C6-C20)-aryl-(C1-C12)-alkyl, —(C6-C20)-aryl-O—(C1-C12)-alkyl, —(C3-C20)-heteroaryl, —(C3-C20)-heteroaryl-(C1-C12)-alkyl, —(C3-C20)-heteroaryl-O—(C1-C12)-alkyl, —COOH, —OH, —SO3H, —NH2, halogen.
US11028109B2	Phosphorus-containing compound, manufacturing method thereof and flame-retardant thermoset The present disclosure provides a phosphorus-containing compound, which includes a structure represented by formula (I). Formula (I) is defined as in the specification. The present disclosure further provides a flame-retardant thermoset made by the phosphorus-containing compound including the structure represented by formula (I). The present disclosure also provides a manufacturing method for the phosphorus-containing compound.
US11028108B2	Method for producing dialkylaminosilane A method for safely and efficiently producing high-purity dialkylaminosilane. Dialkylamine is fed simultaneously during feeding chlorosilane in the presence of metal to cause reaction. For example, chlorosilane and dialkylamine are fed, and then only dialkylamine is fed to cause reaction, whereby dialkylaminosilane is produced.
US11028107B2	Stable silylating reagents The present invention is directed to compositions for silylating organic substrates containing C—H or O—H bonds, especially heteroaromatic substrates. The compositions are derived from the preconditioning of mixtures of hydrosilanes or organodisilanes with bases, including metal hydroxide and metal alkoxide bases. In some embodiments, the preconditioning results in the formation of reactive silicon hydride species.
US11028106B2	Method for producing tetraalkoxysilane An object of the present invention is to provide a method capable of producing a tetraalkoxysilane with a high energy efficiency and with a high yield. The present invention provides a method for producing a tetraalkoxysilane, the method including: a first step of reacting an alcohol with a silicon oxide; and a second step of bringing a vaporized component of the reaction mixture obtained in the first step into contact with a molecular sieve.
US11028105B2	Difluoromethyl and difluoromethylene transfer reagents Disclosed herein are borazine, borate, and azaborinine compounds and compositions, methods of making said compounds and compositions, and methods of forming aromatic difluorocarbon compounds and difluorocarbon compounds.
US11028104B2	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same The invention relates to a xanthine derivative defined by chemical formula I or a salt thereof, its use as a medicament, especially for use in the treatment of serotonin-related diseases or disorders, and a pharmaceutical preparation comprising the xanthine derivative. The novel xanthine compounds are capable of inhibiting tryptophan hydroxylases (TPH) involved in the biosynthesis of serotonin and are effective in influencing the serotonin level in the body.
US11028103B2	Derivatized 3-styryl-cephalosporins Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
US11028098B2	4-phenylpiperidines, their preparation and use The present invention provide a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is H, OH, or halogen; B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole, wherein the heterocycle is other than chloro substituted indole; and the pyrazole, when substituted, is substituted with other than trifluoromethyl, or a pharmaceutically acceptable salt thereof.
US11028097B2	Thienopyrimidine compounds Compounds of formula (I) are A2B receptor antagonists: Wherein R1 is optionally substituted aryl or an optionally substituted 5- or 6-membered heteroaryl ring; R2 and R3 are independently selected from hydrogen, C1-C6 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-(C1-C6)-alkyl, aryl-(C1-C6)-alkyl optionally substituted in the ring part thereof, a 5- or 6-membered monocyclic heterocyclic group optionally linked via a C1-C6 alkylene chain and optionally substituted in the ring part thereof, benzimidazol-2-yl-methyl, pyrid-3-yl-carbonyl, or (1-methyl-piperidin-4-yl)-carbonyl-methyl; or R2 and R3 taken together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6-membered ring; R4 is C1-C3 alkyl, C2-C3 alkenyl, —N(—R5)—R6, or optionally substituted heteroarylmethylamino; and R5 and R6 are independently selected from hydrogen or C1-C3 alkyl; or R5 and R6 taken together with the nitrogen atom to which they are attached form an optionally substituted 4- to 6-membered saturated ring.
US11028095B2	Spiro-lactam and bis-spiro-lactam NMDA receptor modulators and uses thereof Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders. Orally delivered formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
US11028093B2	4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3 and R4 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of JAK kinase-associated diseases and disorders, such as autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
US11028089B2	Pyrimido-diazepinone kinase scaffold compounds and methods of treating DCLK1/2-mediated disorders The present invention relates to use of pyrimido-diazepinone compounds that are able to modulate protein kinases such as doublecortin-like kinase (DCLK1) and doublecortin-like kinase 2 (DCLK2), which are members of serine/threonine-protein kinase family and Ca2+/calmodulin-dependent protein kinase class of enzymes, and the use of such compounds in the treatment of various diseases, disorders or conditions.
US11028087B2	2,6-disubstituted-9-cyclopentyl-9H-purines, use thereof as medicaments, and pharmaceutical compositions The present invention relates to novel 2,6-disubstituted-9-cyclopentyl-9H-purines of general formula I, capable of inhibiting the activity of kinases such as FLT3, CDKs and PDGFRs in cancer and other related proliferative diseases. The invention further includes pharmaceutical compositions containing the 2,6-disubstituted-9-cyclopentyl-9H-purines. Compounds of the present invention can be used as active ingredients of a pharmaceutical compositions for treating acute myeloid leukemia (AML).
US11028083B2	Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases The present invention relates to ethanediamine-heterocycle compounds that are able to act as inhibitors of PRMTs (protein arginine methyltransferases) for treating cancer and other diseases mediated by PRMTs.
US11028082B2	Process for the preparation of a novel umeclidinium synthesis intermediate The present invention relates to a process for the preparation of a novel and versatile synthesis intermediate and its use in the preparation of umeclidinium. The invention also relates to some reference standards allowing to detect impurity traces recurring in the preparation of umeclidinium and a process for their preparation.
US11028079B2	Small molecule BET bromodomain inhibitors and uses thereof The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
US11028078B2	Itraconazole analogs and use thereof Provided herein are Itraconazole analogs. Also provided herein are methods of inhibition of Hedgehog pathway, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, angiogenesis and treatment of disease with Itraconazole analogs.
US11028076B2	Inhibiting ataxia telangiectasia and Rad3-related protein (ATR) Novel compounds inhibiting ATR protein kinase include compounds of formula (I) disclosed herein, as well as liposome formulations comprising ATR protein kinase inhibitor compounds. The compositions are useful for the treatment of cancer.
US11028072B2	2,4-diamino-6-ethylpyrimidine derivatives with antimalarial activities against Plasmodium falciparum The present invention relates to 2,4-diamino-6-ethylpyrimidine derivatives that are inhibitors of wild type and quadruple mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum. They also show in vitro antimalarial activities against Plasmodium falciparum for both wild type and mutant that are comparable to or better than pyrimethamine. In addition, the compounds of the present invention show a good selectivity to Plasmodium falciparum and exhibit lower cytotoxicity than pyrimethamine.
US11028071B2	Indazole derivatives as alpha v integrin antagonists The present invention provides compounds of Formula (Ia) or (Ib): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds are antagonists to αV-containing integrins. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with dysregulation of αV-containing integrins, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.
US11028068B2	Somatostatin modulators and uses thereof Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
US11028066B2	Inhibitors of lysine specific demethylase-1 The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds as exemplified as follows, The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
US11028065B1	Continuous method for preparing carbonate esters In one embodiment, a continuous process for preparing organic carbonate solvent of Formula (I) as described herein comprises contacting a first reactant (an alcohol) with a reactive carbonyl source (carbonyldiimidazole (CDI) or an alkylchloroformate) in the presence of a catalyst in reaction stream flowing through a continuous flow reactor at temperature 20° C. to about 160° C. and at a flow rate providing a residence time in the range of about 0.1 minute to about 24 hours; collecting a reactor effluent exiting from the continuous flow reactor; recovering a crude product from the reactor effluent; and distilling the crude product to obtain the organic carbonate compound of Formula (I). In another embodiment, the first reactant is an epoxide and the carbonyl source is carbon dioxide.
US11028058B2	Heterocyclic compounds as adenosine antagonists Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
US11028056B2	Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound The present invention provides a method for industrially producing: a pyrimidine compound having pest control efficacy; 2-[4-(trifluoromethyl)phenyl]ethylamine which is a production intermediate of the pyrimidine compound; a phenylethylamine compound useful as a pharmaceutical and agrochemical intermediate; and further a 3-arylpropionamide compound and a 3-arylpropionic acid ester compound useful as production intermediates of the phenylethylamine compound. The 3-arylpropionamide compound or the 3-arylpropionic acid ester compound can be efficiently and industrially produced in a single step by reacting a compound represented by formula (1) (wherein X represents a chlorine atom or a bromine atom; and Y represents an alkyl group optionally substituted with fluorine atom(s), a hydrogen atom, a fluorine atom, a cyano group, an alkylcarbonyl group, a dialkylamino group, or the like) with acrylamide or an acrylic acid ester in the presence of a metal catalyst and a reducing agent.
US11028054B2	1, 4, 6-trisubstituted-2-alkyl-1H-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitors The present invention provides 1, 4, 6-trisubstituted-2-alkyl-1H-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitor compounds of formula (I), which may be therapeutically useful as DHODH inhibitors, in which R1 to R3 and ‘m’ have the meanings given in the specification, and pharmaceutically acceptable salts or stereoisomer thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage in inhibiting DHODH. The present invention also provides methods for synthesizing 1, 4, 6-trisubstituted-2-alkyl-1H-benzo[d]imidazole derivatives of formula (I). The present invention also provides pharmaceutical formulations comprising at least one of the DHODH inhibitor compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient.
US11028050B2	Salts and polymorphs of a PDE4 inhibitor Provided herein are free base crystalline forms and crystalline salts of Compound 1.
US11028043B2	N-hydroxyalkylated polyamines, methods of making n-hydroxyalkylated polyamines, and fluids containing an n-hydroxyalkylated polyamine Methods of making N-hydroxyalkylated polyamines are provided, in which the method includes reacting a polyamine comprising Formula (XXIV): with a cyclic oxide to produce the N-hydroxyalkylated polyamine, where R1 and R2 are independently a —C or —CH group; R3 is an aliphatic hydrocarbyl; and R4 and R5 are independently acyclic hydrocarbyls, or are covalently connected to form an unsaturated cyclic hydrocarbyl.
US11028042B2	Process for preparing an aromatic polyamine mixture A process for preparing an aromatic polyamine mixture including 4,4′-methylenedi(phenylamine) and higher homologues of MDA is provided. The process includes steps of (i) reaction of aniline with formaldehyde by means of an acid catalyst to form a crude product mixture (I), (ii) neutralization of the crude product mixture (I) and removal of the salts formed; (iii) isolation of aniline; (iv) distillation of the resulting crude product mixture so as to separate off (iv-1) a mixture (II) of MDA isomers (II-1) containing from 8 to 20% by weight of 4,4′-methylenedi(phenylamine) and not more than 0.3% by weight of secondary components (II-2) and (iv-2) a low boiler mixture of at least 55% by weight of secondary components (II-2) and MDA isomers (II-1); and (v) recirculation of the mixture (II).
US11028030B2	Plant extract compositions for forming protective coatings Described herein are methods of preparing cutin-derived monomers, oligomers, or combinations thereof from cutin-containing plant matter. The methods can include heating the cutin-derived plant matter in a solvent at elevated temperature and pressure. In some preferred embodiments, the methods can be carried out without the use of additional acidic or basic species.
US11028029B2	Process for the production of 2,3,3,3-tetrafluoropropene The present invention relates to a process for the production of 2,3,3,3-tetrafluoropropene comprising the stages: i) in a first reactor, bringing 2-chloro-3,3,3-trifluoropropene into contact with hydrofluoric acid in the gas phase in the presence of a catalyst, in order to produce a stream A comprising 2,3,3,3-tetrafluoropropene, HF and unreacted 2-chloro-3,3,3-trifluoropropene; and ii) in a second reactor, bringing hydrofluoric acid into contact, in the gas phase in the presence or absence of a catalyst, with at least one chlorinated compound selected from the group consisting of 1,1,1,2,3-pentachloropropane, 2,3-dichloro-1,1,1-trifluoropropane, 2,3,3,3-tetrachloropropene and 1,1,2,3-tetrachloropropene, in order to produce a stream B comprising 2-chloro-3,3,3-trifluoropropene, characterized in that the stream A obtained in stage i) feeds said second reactor used for stage ii); and in that the pressure at the inlet of said first reactor of stage i) is greater than the pressure at the inlet of said second reactor of stage ii).
US11028027B2	Process for producing 2-chloro-3,3,3-trifluoropropene The present invention relates to a process for the production of 2-chloro-3,3,3-trifluoropropene comprising the stages of: a) providing a stream A comprising at least one of the compounds selected from the group consisting of 2,3-dichloro-1,1,1-trifluoropropane, 1,1,1,2,3-pentachloropropane, 1,1,2,3-tetrachloropropene and 2,3,3,3-tetrachloropropene; b) in a reactor, bringing said stream A into contact with HF in the presence or absence of a catalyst in order to produce a stream B comprising 2-chloro-3,3,3-trifluoropropene; characterized in that the electrical conductivity of said stream A provided in stage a) is less than 15 mS/cm.
US11028024B2	Reaction products and methods for making and using the same Reaction products and methods for making and using the same are provided. The reaction products particularly may include adducts of two or more reactants. The adducts particularly can incorporate a nitrification inhibitor, such as DCD. In particular embodiments, reaction products may be formed from the reaction of formaldehyde, DCD, urea, and an ammonia source. The adducts may be included in agricultural products, including fertilizer compositions and nitrification inhibitor systems. Fertilizer compositions including the adducts can be beneficial for reducing leaching of nitrification inhibitors applied to soil.
US11028023B2	Method for preparing mesoporous sound-absorbing material particles and mesoporous sound-absorbing material particles The invention discloses a method for preparing mesoporous sound-absorbing material particles and mesoporous sound-absorbing material particles. The preparation method comprises the following steps. In step 1, sound-absorbing material powder and a templating agent are mixed with a binding agent and water to form sol slurry, the templating agent is an organic monomer or a linear polymer, and the templating agent has a purity greater than 95%. In step 2, the sol slurry is dropped into forming oil, and the droplets of the sol slurry are aged in the forming oil to form gel particles. In step 3, the gel particles are taken out from the forming oil and the gel particles are dried to form mesoporous sound-absorbing material particles. In step 4, the mesoporous sound-absorbing material particles are roasted.
US11028019B2	Boron carbide composite The present disclosure relates to boron carbide (B4C) composite material and the method of making and using the boron carbide (B4C) composite.
US11028018B2	Erosion-resistant ceramic material, powder, slip and component The use of magnesium oxide, reactive alumina and aluminium oxide as a base provides for a new erosion-resistant material upon sintering.
US11028017B2	Fast-drying screed and screed mixture for producing the screed The invention relates to screed mixtures, comprising an inorganic binder, processing additives and drying additives. Self-levelling floor screeds according to the invention can be produced from these screed mixtures, said self-levelling floor screeds drying much more quickly than self-levelling floor screeds with the same composition, but which contain no drying additives.
US11028015B2	Glass ball having specific Young's modulus and coefficient of thermal expansion A glass ball has a density of 2.3 to 3.2 g/cm3, a Young's modulus of 60 to 150 GPa, and an average coefficient of thermal expansion at 50 to 350° C. being 40×10−7 to 120×10−7/° C. The glass ball is formed of a glass material including, as represented by mole percentage based on oxides, 30 to 75 mol % of SiO2, 2 to 30 mol % of Al2O3, and 5 to 25 mol % of R2O, where R is at least one kind selected from Li, Na and K. The glass ball includes a compressive stress layer in a surface thereof.
US11028014B2	Coated glass-based articles with engineered stress profiles A glass-based substrate having a Young's modulus, a first surface, and a second surface. A coating, on at least one of the first and second surfaces, having a Young's modulus equal to or greater than the substrate Young's modulus. A compressive region having a compressive stress CS of from 750 MPa to 1200 MPa at a surface and extending to a depth of compression (DOC). The compressive region having a first portion and a second portion, the first portion extending from the first surface up to a first depth, the second portion extending from the first depth to the DOC, points in the first portion comprise a tangent having a slope that is less than −15 MPa/micrometers and greater than −60 MPa/micrometers, and points in the second portion comprise a tangent having a slope that is less than or equal to −1 MPa/micrometers and greater than −12 MPa/micrometers.
US11028013B2	Chemically strengthened glass and method for producing the same A chemically strengthened glass has a compressive stress layer formed in a glass surface layer by ion exchange. The compressive stress layer includes at least two types of stress patterns of a stress pattern A close to a glass surface and a stress pattern B on an inner side of the glass. In the stress pattern A, compressive stress increases as going inward from the glass surface. In the stress pattern B, compressive stress decreases as going inward from the glass surface. Depth of compressive stress layer in the stress pattern B is 90 μm or more from the glass surface. Compressive stress α MPa of the glass surface in the stress pattern A and compressive stress β MPa at a point where the stress pattern A and the stress pattern B cross each other satisfy a relation of β>α.
US11028012B2	Low solar heat gain coatings, laminated glass assemblies, and methods of producing same The invention provides transparent conductive coatings based on indium tin oxide. In some embodiments, the coating includes two indium tin oxide films and two nickel alloy films. Also provided are laminated glass assemblies that include such coatings.
US11028009B2	Coefficient of thermal expansion filler for vanadium-based frit materials and/or methods of making and/or using the same Certain example embodiments relate to seals for glass articles. Certain example embodiments relate to a composition used for sealing an insulted glass unit. In certain example embodiments the composition includes vanadium oxide, barium oxide, zinc oxide, and at least one additional additive. For instance, another additive that is a different metal oxide or different metal chloride may be provided. In certain example embodiments, a composition may be combined with a binder solution that substantially or completely burns out by the time the composition is melted. In certain example embodiments, a CTE filler is included with a frit material. In certain example embodiments, a vacuum insulated glass unit includes first and second glass substrates that are sealed together with a seal that includes the above-described composition.
US11028007B2	Automotive glass compositions, articles and hybrid laminates Embodiments of glass articles comprising an anneal point (° C.) and a softening point (° C.), and the relationship of (anneal point+softening point)/2 in a range from about 625° C. to about 725° C. are disclosed. In one or more embodiments, the glass articles include a glass composition including SiO2 in an amount in a range from about 63 mol % to about 75 mol %; Al2O3 in an amount in a range from about 7 mol % to about 13 mol %; R2O in an amount from about 13 mol % to about 24 mol %; P2O5 in an amount in a range from about 0 mol % to about 3 mol %, and one or both of MgO and ZnO. Laminates including such glass articles, and methods for making such laminates are also disclosed.
US11027996B1	Crown ether functionalized substrates A method for making crown ether functionalized substrates, which includes modifying crown ether-based molecules by reacting with carboxylic acid functionalize chains. The crown ether-based molecules are then attached to substrates, thereby forming crown ether functionalized substrates.
US11027993B2	Oil sands tailings treatment Processes of consolidating oil sands tailings which includes fines and process water are disclosed. The processes include mixing the oil sands tailings with a highly water soluble salt or an aqueous solution thereof to destabilize and consolidate solids in the tailings, e.g., to destabilize and consolidate fines in the tailings and separating the consolidated solids from the process water. A water soluble polymer and coarse particles, e.g., sand, can also be used in the treatment of oil sands tailings.
US11027992B2	Iron-based amorphous electrode material for wastewater treatment and use thereof An iron-based amorphous electrode material for industrial wastewater treatment, wherein the material is amorphous alloy used as an electrode for electrochemical degradation of industrial wastewater, and the atom percentage of iron element in the alloy being 40-84%, wherein a method for treating dye wastewater by using the iron-based amorphous electrode material and a use of the iron-based amorphous electrode material in the electrochemical degradation of industrial wastewater are also disclosed.
US11027991B2	Electrolytic biocide generating system for use on-board a watercraft The present disclosure relates to a biocide generating system for inhibiting bio-fouling within a water system of a watercraft. The water system is configured to draw water from a body of water on which the watercraft is supported. The biocide generating system includes an electrode arrangement adapted to be incorporated as part of an electrolytic cell through which the water of the water system flows.
US11027984B2	Urea process with controlled excess of CO2 and/or NH3 A process for producing urea with controlled excess of CO2 and/or NH3. The process includes the steps of: reforming the hydrocarbon feed gas, thereby obtaining a synthesis gas comprising CH4, CO, CO2, H2 and H2O, shifting the synthesis gas, removing CO2 from the synthesis gas, removing residual H2O and/or CO2 from the synthesis gas, removing CH4, CO, Ar and/or He, and adding stoichiometric nitrogen to produce NH3 to the synthesis gas, synthesizing NH3 to obtain a NH3 product, and adding at least part of the product CO2 and at least part of the NH3 product to a urea synthesis step to make a urea product. The amount of excess CO2 and/or NH3 is controlled by adjusting the steam/carbon in the reforming step and/or the H2O addition upstream the shift step and/or adjusting the inlet temperature to at least one or more shift steps.
US11027979B2	Process for hydrogenating silicon tetrachloride The invention relates to a process for hydrogenating silicon tetrachloride in a reactor, wherein a reactant gas containing hydrogen and silicon tetrachloride is heated to a temperature between 850° C. and 1600° C. by means of at least one heating element, which comprises a graphite surface, wherein the temperature of the heating element is between 850° C. and 1600° C. The process is characterized in that a nitrogen compound is added to the reactant gas in a substance amount fraction of 0.1 to 10% based on hydrogen.
US11027978B2	Silicon nanoparticle-containing hydrogen polysilsesquioxane, calcined product thereof, production method therefor, active material, negative electrode, and lithium ion battery A silicon nanoparticle-containing hydrogen polysilsesquioxane calcined product to be covered by the invention, represented by general formula SiOx2Hy2 (0.3
US11027977B2	Method of manufacturing tantalum carbide material A method of manufacturing a tantalum carbide material of the present invention includes heating a tantalum material (1) interposed between a pair of graphite guide members (2 and 3) under an atmosphere of a carbon source-containing gas (4) at 1,500° C. or higher for 0.5 hours or longer.
US11027976B2	Ferroelastic ceramic compositions, applications thereof, and related methods An example ferroelastic ceramic composition includes at least one compound having a relative chemical formula of AXBYC(1-X-Y)D. Element A, element B, and element C are independently selected from different members of the group consisting of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, and lutetium. Element D is selected from the group consisting of phosphate, niobate, and tungstate. X and Y are each equal to or greater than zero and less than one. X and Y are collective less than one.
US11027975B2	Method to make phosphoric acid and ammonium phosphates from phosphate minerals A method of producing phosphoric acid from at least one mineral containing phosphate and an element which is calcium, magnesium, iron, or aluminum. The method includes contacting the at least one mineral (or a combination of them) with a cation exchanger for a time and at a temperature sufficient to yield phosphoric acid from the mineral.
US11027971B2	Method for producing hydrogen A method for producing hydrogen of the present invention includes thermally reducing a reaction medium in which CeO2 is doped with a metal other than Ce and bringing the thermally reduced reaction medium into contact with water to oxidize the reaction medium and to generate the hydrogen. When a reaction temperature in the thermally reducing the reaction medium is defined as T1 [° C.] and a reaction temperature in the bringing the thermally reduced reaction medium into contact with the water is defined as T2 [° C.], a relation of T1−T2≤150 is satisfied. It is preferred that a series of processes including the thermally reducing the reaction medium and the bringing the thermally reduced reaction medium into contact with the water is repeated.
US11027968B2	Semiconductor device with discharge path, and method for producing the same In a semiconductor device, a first substrate and a second substrate are bonded to each other through an insulating film. A hermetically sealed chamber is provided between the first substrate and the second substrate, and a sensing part is enclosed in the hermetically sealed chamber. The second substrate has a through hole penetrating in a stacking direction of the first substrate and the second substrate and exposing the first surface of the first substrate. A penetrating electrode is disposed on a wall surface of the through hole of the second substrate, and is electrically connected to the sensing part. A discharge path is provided, at a position located between the hermetically sealed chamber and the through hole for releasing outgas generated during bonding from the hermetically sealed chamber to the through hole.
US11027958B2	Liquid distribution system A liquid distribution system is provided that allows for filling multiple liquid-holding containers simultaneously and evenly. The system includes a hollow-bodied unit with a plurality of bowl-shaped channels and corresponding spouts that is structured such that liquids can be collected and drained out at one time into multiple bottles or other containers situated below the hollow-bodied unit and held in a structure unit below.
US11027957B2	Drink filling system A drink filling system including: a bottle molding section; a sterilizing section that sterilizes a molded bottle; a rinsing section that rinses the bottle; a filling section that fills and seals the bottle; and a conveying unit that conveys the bottle from the molding section to the filling section. A chamber covers a portion extending from the sterilizing section to the filling section, an atmosphere shut-off chamber is between a sterilizing section chamber and a rinsing section chamber, an exhaust unit for exhausting the atmosphere shut-off chamber and/or the sterilizing section chamber, a clean air supply unit for flowing a clean air from a filling section chamber into the atmosphere shut-off chamber through the rinsing section chamber or for further flowing the air into the sterilizing section chamber, and the air-flow flowing therein is exhausted by the exhaust unit.
US11027954B2	Multipurpose device A stand-alone multipurpose lifting device includes an elongated vertical support section having a planar base section with an upper end including a substantially U-shaped receiving bearing including a plurality of pivot slots on either side of the U-shaped bearing and an angled elongated lever arm section. The lever arm section includes an angle strengthening gusset and a detachable extension arm and handle including a receiving sleeve for fitting over and receiving the end of the lever arm section. A device for cracking a seal formed around a manhole cover includes a horizontal cross bar section including a bottle jack holder recess, a bottle jack retaining means, two opposed leg sections, support struts between the horizontal cross bar and leg sections and a jack cap section including two lifting eyes including a hook and lifting chains for attaching to a manhole lifting arm detachably connected to a manhole cover.
US11027953B2	Method for monitoring the road path of a truck and a floor conveyor A method for monitoring the travel path of an industrial truck, comprising the steps of: determining a braking distance of the industrial truck on the basis of at least one operating parameter of the industrial truck, adjusting a travel path area monitored by a monitoring device on the basis of the determined braking distance by adjusting the alignment of the monitoring device, decelerating the industrial truck when an obstacle enters the travel path.
US11027945B2	Wall securing assembly for securing an elevator component A wall securing assembly is integrated into an elevator shaft wall for securing a guide rail to the wall. The wall has a first concrete region that is reinforced with reinforcements and a second concrete region that is not reinforced. The second region covers the first region and has a surface that is exposed to the surroundings. The securing assembly has an elongated profile of C-shaped cross-section embedded solely into the second region and oriented in the vertical direction of the wall. Since tensile forces acting on a guide rail in an elevator shaft are very low, it is acceptable to secure the guide rail to the profile that is cast into the second region covering the reinforcement. The profile is anchor element-free and can be arranged in the wall vertically whereby guide rail holding consoles can be secured to the profile at any height.
US11027940B2	Winding unit and spiral electric wire manufacturing method A winding device capable of easily winding an electric wire and a method of manufacturing a spiral electric wire are provided. The electric wire delivered by the delivery device is guided by the guide device toward the center portion of the projecting portion. The projecting portion of the winding device has an inclined surface whose outer diameter increases toward the base portion from the tip end on its outer peripheral surface. As a result, the electric wire can be wound around the projecting portion by utilizing the force of the delivery device, and the electric wire can be easily wound up.
US11027939B2	Sheet folding device A sheet folding device includes a folding path, a folding roller including at least two rollers that engage with each other to form a folding nip and rotate, a folding blade to be movable to an insertion location at which at least one sheet of paper on the folding path is pushed into the folding nip, and to a retreat location escaping from the folding path, a guide member to move along with the folding blade, located at at least one side of the folding blade, and to push the paper towards the folding roller when the folding blade is moved to the insertion location and an elastic member to apply elasticity to the guide member towards the folding roller.
US11027938B2	Medium transport device and image forming apparatus A medium transport device includes a transporting member, a medium offsetting member, a guide member, and an interlocking member. The guide member is located upstream of the transporting member in a medium transport direction. The guide member is movable between a first position, in which the guide member guides the medium toward the medium accommodating member, and a second position, in which the guide member guides the medium to a destination different from the medium accommodating member, to guide the medium. The interlocking member moves the guide member between the first position and the second position in conjunction with a movement of the medium offsetting member in a width direction of the medium offsetting member.
US11027934B2	Multi-feed detection device, multi-feed detection method, and electronic device A multi-feed detection device includes a transmission circuit substrate on which an ultrasonic transmitter transmitting an ultrasonic wave is installed, and an ultrasonic receiver receiving the ultrasonic wave. The ultrasonic transmitter transmits the ultrasonic wave in a direction intersecting a thickness direction of the transmission circuit substrate and at least one of the ultrasonic transmitter and the ultrasonic receiver has a plurality of ultrasonic elements.
US11027931B1	Marker band locator system A marker band locator system locates a marker band, from a plurality of marker bands in a hopper, into a band receiver for further processing. A hopper is configured to loosely hold a plurality of marker bands and a band receiver, configured in an indexer, is configured under the hopper such that marker bands gravity feed down to the band receiver. A vacuum source produces a vacuum on the band receiver and if a marker band is properly located therein, the marker band forms a seal with the band receiver and the vacuum pressure exceeds a threshold vacuum pressure level. The indexer then actuates to a secondary position for further processing and removal of the marker band. If the vacuum pressure does not exceed the threshold, a burst of air jostles the marker bands in the hopper until a marker band is seated properly.
US11027928B2	Compact collator, system and method of use A compact collator for sorting and collating product containers includes a laner, a pattern conveyor, a cross-pusher assembly and a plurality of interchangeable inserts. The laner has a first movable conveyor for conveying product containers through the laner, and defines an infeed area. The pattern conveyor has a second movable conveyor positioned down-stream from the infeed area and off-set 90 degrees from the first moveable conveyor. The cross-pusher assembly includes a cross-pusher arm that the interchangeable inserts are configured to be engaged to. Each insert defines a unique face contour that corresponds to the profile shape of at least one type of product container.
US11027924B2	Device for moving endless conveyor chains In the present device for moving endless conveyor chains, link conveyor chains are moved within C-shaped guides. Mounted in breaks in the guides is a chain actuating mechanism configured as two parallel chain drives. As the conveyor chains move, their rollers are engaged by grips disposed on the chain drives. The invention makes it possible to create a compact device for smoothly and evenly moving endless conveyor chains in different planes.
US11027913B2	Capsule assembly comprising a capsule and a conveyor cap configured to open said capsule A capsule assembly including a capsule for preparation of beverages and a conveyor cap mounted on the capsule for conveying the beverage exiting the capsule. The capsule includes an inlet wall, an outlet wall, and a lateral wall defining an internal volume inside which at least one beverage ingredient is housed. The outlet wall includes one or more capsule beverage outlets. The conveyor cap is mounted on the capsule to define an enclosure space between the outlet wall and an inner surface of the conveyor cap. The conveyor cap includes one or more beverage delivery openings and is movably mounted on the capsule. The capsule beverage outlets and the conveyor cap are configured to interact so that the capsule beverage outlets are opened by the conveyor cap due to a relative movement between the capsule and the conveyor cap.
US11027909B2	Automated flowable material dispensers and related methods for dispensing flowable material An automated flowable material dispenser for dispensing flowable material from a flowable material container is provided. In one embodiment, the dispenser may include a dispenser housing configured to receive the flowable material container therein, a solenoid valve assembly positioned within the dispenser housing, and a biasing member configured to bias the flowable material container toward the solenoid valve assembly and to move the flowable material container from an unactuated configuration to an actuated configuration. The dispenser housing may define a dispensing opening along a bottom end of the dispenser housing and may be configured to move between an open configuration and a closed configuration. The solenoid valve assembly may be positioned above the dispensing opening and configured to control dispensing of the flowable material from the dispenser.
US11027907B2	Container with closures A container having a full perimeter lid pressure or tensioning mechanism. The container can also have a removable temperature sensor to monitor an internal compartment temperature. A pressure regulator is also disclosed to regulate a pressure differential and vacuum of the container in order to control an amount of vacuum sealing of the lid to the container.
US11027906B2	Fitment with blend component and flexible container with same The present disclosure provides a fitment. In an embodiment, a fitment is provided and includes a top portion, a base, and a channel extending through the top portion and the base for passage of a flowable material. The fitment is composed of a polymeric composition. The polymeric composition includes (i) from 70 to 90 weight percent of a high density polyethylene (HDPE) having a density from 0.940 g/cc to 0.970 g/cc, a melt temperature, Tm, greater than 125° C., and a melt index from 1 g/10 min to 50 g/10 min; and (ii) from 30 to 10 weight percent of an olefin-based elastomer having a density from 0.860 g/cc to 0.905 g/cc, a melt index from 0.2 g/10 min to 50 g/10 min, and a Tm less than 125° C.
US11027901B2	Transfer lid A transfer lid for a fluid container, having an attachment collar for removably attaching the transfer lid to the fluid container, and an inner collar arranged generally concentrically with and spaced inwardly from the attachment collar, the inner collar having a vent opening such as a vent slot extending therethrough.
US11027899B2	Closure device A closure device for closing a container is provided. The closure device (10) includes a ring (28), a cover (30) and a cap (32). The ring has a top wall (34) and a flexible skirt (36) extending downwardly from the top wall. The flexible skirt includes a plurality of spaced-apart first legs (40) and a plurality of spaced-apart second legs (42) arranged in an alternating manner. Each of the first and second legs has a first end at the top wall and an opposing second end. The first legs are different from the second legs. An interior surface of each first leg has a first inwardly protruding ledge (44) between the first and second ends. Each second leg has a second inwardly protruding ledge (48) at the second end. An interior surface of each second leg has a flexible tongue (50) and a recess (52) configured to receive the flexible tongue. The tongues are adapted to retain an elastomer stopper (14).
US11027879B2	Keg chime The present invention relates to a keg chime configured to be mounted to a keg, for example a blow moulded plastic keg. The chime may include a handle that has a waveform profile when viewed in cross-section along a length of the handle. The handle may include a first set of one or more regions of inflection that provide a first surface of the handle and a second set of one or more regions of inflection that provide an opposing second surface of the handle. The chime may be configured to be connected to a sleeve for surrounding at least part of a body portion of the keg. The interface between the chime and the sleeve may be configured to permit axially outward movement of the chime with respect to the sleeve in order to accommodate axial expansion of the keg.
US11027877B2	Locking carton A locking carton, locking mechanism and method includes an insert including a bridge having at least one pair of locking tabs at the ends thereof and material cutouts in the bottom panel and side walls adjacent to the bridge and an outer sleeve including at least one pair of locking notches corresponding to the at least one pair of locking tabs when in a locked position.
US11027874B2	Labelling apparatus and method This invention relates to application of labels from a supply of labels which are defined in sheet material and in which adjacent labels are joined together by a line of weakening to form a continuous label supply. The label sheet material is provided with a layer of adhesive which contacts with a backing layer to form the label supply. The leading label is provided with a leading edge portion detached from the backing layer from application at an application point to an article and the article and label feed movement are controlled such that the remainder of the label can be detached from the backing layer, and the line of weakening broken effectively and accurately and without the need for the sheet material of the label supply and/or backing layer to have a thickness to provide the level of rigidity or stiffness of the material which is conventionally required, thereby reducing material usage and wastage.
US11027873B2	Stamp application A method and apparatus for applying stamps to a group of packages wherein the stamps are arranged in a predetermined pattern and the packages in the group are arranged in a different pattern, using an apparatus having one or more carriages moveable in the x- and/or y-directions.
US11027869B2	Method for separate sterilization and aseptic assembly Disclosed is an inventive method for an aseptic assembly of a multi-component medical device. In this method a first component of the medical device is provided in a first container and a second component of the medical device is provided in a second container. Each of the first and second separated containers have a rupturable portion. The first component in the first container is sterilized using a first sterilization technique and the second component in the second container is sterilized using a second sterilization technique. The first and second containers are joined while arranging the rupturable portions in an overlapping configuration which is aseptically sealed against the surroundings. Finally, one of the components is transferred through the rupturable portions and the components are aseptically assembled to form the medical device as a sterile package.
US11027868B2	Method for handling food portions with a rotation device The disclosure relates to an apparatus for handling food portions which comprises a first conveying device, a rotation device with a second conveying device forming a depositing surface which can be turned about a vertical axis, a third conveying device, and a control unit. The first conveying device is configured such that it can at least in regions be arranged above the rotation device. The control unit is adapted to control the first conveying device such that food portions are deposited in a format arrangement by the first conveying device from above onto the depositing surface of the rotation device, to control the rotation device to rotate the depositing surface with the food portions about the vertical axis, and to control the second conveying device to convey the turned food portions onward onto the third conveying device.
US11027862B2	Cold blow-fill-seal packaging system and process A method and system for cold blow-fill-seal packaging of a product. The method and system are directed to maintaining a relatively cold temperature of the product to be packaged during the flow-fill-seal process. This accomplished via the use of one or more of, for example, a heat-exchanger in the system, insulated flow lines and steps taken during the procedure to maintain the temperature of the product below a certain level.
US11027860B2	Delivery apparatus An air accelerator dosing tube for a form/fill/seal machine used to package fine cut tobacco material includes an axially-adjustable annular venturi communicating with the particulate material passage. A lining of polyether ether ketone optionally covers surfaces exposed to the particulate material. A metering assembly for delivering predetermined quantities of particulate material at predetermined time intervals may also be fabricated from polyether ether ketone. Each dosing tube is adapted for calibration by adjustment of the annular venturi to produce a predetermined force at a predetermined stand-off distance. In operation, consistent simultaneous operation of multiple dosing tubes, each of which has been calibrated, gives substantially uniform deposit of particulate material in pouch-type packages. The particulate material may include finely cut tobacco in addition to humectants, flavorants, and other tacky substances.
US11027859B2	Variable stiffness flyer plate for penetration device A penetration device including a casing, a propellant positioned in the casing, and a flyer plate. The flyer plate is coupled to the casing and adjacent to the propellant. The flyer plate includes a center portion having a substantially constant first thickness and includes a peripheral portion around the center portion and defining an edge. The peripheral portion includes one or more recesses in a first surface of the peripheral portion.
US11027856B2	Surfacing materials for composite structures Multifunctional surfacing materials for use in composite structures are disclosed. According to one embodiment, the surfacing material includes (a) a stiffening layer, (b) a curable resin layer, (c) a conductive layer, and (d) a nonwoven layer, wherein the stiffening layer (a) and the nonwoven layer (d) are outermost layers, and the exposed surfaces of the outermost layers are substantially tack-free at room temperature (20° C. to 25° C.). The conductive layer may be interposed between the curable resin layer and the stiffening layer or embedded in the curable resin layer. According to another embodiment, the surfacing material includes a fluid barrier film between two curable resin layers. The surfacing materials may be in the form of a continuous or elongated tape that is suitable for automated placement.
US11027853B2	Distributed control and monitoring system for multiple platforms Control systems and methods for controlling an engine. The control system includes a computation module and an input/output (I/O) module attached to the engine. The computation module is located in an area of the engine, or off-engine, that provides a more benign environment than the environment that the I/O module is subject to during operation of the engine. The I/O module includes a first processor and a first network interface device. The computation module includes a second processor with higher processing power than the first processor, and a second network interface device. The control system also includes a sensor configured to provide sensor readings to the first processor. The first processor transmits data based on the sensor readings to the second processor. The control system also includes an actuator operably coupled to the I/O module and that is controlled by the first processor based on commands from the second processor.
US11027850B1	Elevation tracking device The systems and methods provided herein are directed to a device for tracking a jumper's elevation during a parachute jump. The device includes an active sensor for monitoring a distance to the ground, which is disposed at an angle and transmitted from the jumper's calf to reduce the chance of self-obstruction. The device notifies the jumper in one of several ways when a threshold elevation is reached, and may take additional automated actions at particular elevation thresholds.
US11027839B2	Tactical rapid access small unmanned aerial system The invention specifies key small Unmanned Aerial System (sUAS) features which include the tactical mounting of the sUAS to a firearm for rapid access in tactical situations. The invention claims both the fixturing of a sUAS to a firearm and technologies and methodologies to allow for deployment of the sUAS utilizing a single hand of the operator.
US11027838B2	In flight charging system An in-flight charging system includes a first electric air vehicle, a second electric air vehicle, an elevated power supply system (EPSS) and a flexible tension member coupled to the first electric air vehicle and coupled to the second electric air vehicle. The flexible tension member provides power from the second electric vehicle to the first electric vehicle. The EPSS further includes one or more current carrying conductors, wherein the second electric air vehicle travels along the one or more current carrying conductors and receives power transferred from the one or more current carrying conductors.
US11027836B2	Rotorcraft with canted coaxial rotors A rotorcraft has a frame and a plurality of rotors connected to the frame. The frame has a roll axis and a pitch axis. Each of the rotors includes a rotor shaft. The rotor shaft of each of the rotors is canted with respect to at least one of the roll axis and the pitch axis. The rotor shaft of each of the rotors may be canted between 3 and 15 degrees. Each of the rotors may be a co-axial co-rotating rotor. The rotors may be oriented in opposing pairs across the frame. Both rotors in each opposing pair rotate in the same direction. The rotorcraft may include at least two additional rotors, each having a forward cant. Each of the additional rotors may be a co-axial contra-rotating rotor.
US11027835B2	Unmanned aerial vehicle An unmanned aerial vehicle according to various embodiments includes: a housing; a communication circuit, wherein the communication circuit establishes wireless communication with an external controller; and a plurality of propulsion systems connected to the housing, wherein the propulsion systems include: a motor; a rotation shaft having an axis extending in a first direction, wherein a first end is connected to the motor, and wherein the rotation shaft is rotates in a first direction by the motor; a cap structure fixed to the second end of the rotation shaft, a propeller including: a hub including a through-hole formed in the first direction, such that the rotation shaft rotatably passes through the through-hole, wherein the propeller is detachably connected to the cap structure, such that, when an external force is exerted on the blade, the propeller is released from the cap structure to be freely movable along the axis toward the motor.
US11027832B2	Multi-rotor aircraft A multi-rotor aircraft (100) is provided, comprising: a main aircraft assembly (10) comprising a first magnetic medium (13), a main housing (11), and a control motherboard accommodated in the main housing (11), wherein the first magnetic medium (13) is provided on the main housing (11), a slot (1120) is further provided on the main housing (11), and a connection point of the control motherboard is provided in the slot (1120); and a plurality of rotor systems (20), wherein each of the plurality of rotor systems comprises a second magnetic medium (23), a rotor mechanism (21), and a rotor protection cover (22) that is of a hollow annular structure and is fixed outside the rotor mechanism (21), wherein the second magnetic medium (23) is fixed to the rotor protection cover (22) and attracting the first magnetic medium (13), and a pin (2200) matching the slot (1120) is further provided on the rotor protection cover (22). The rotor systems (20) can be quickly mounted on or dismounted from the main aircraft assembly (10), thereby achieving the technical effects of shortening the mounting and dismounting time and improving the operation efficiency.
US11027831B2	Safety rotor A safety rotor system for an aircraft including a flight rotor that is rotationally driven by a drive, the system including: a safety rotor that is rotationally driven during rotation of the flight rotor, the safety rotor including one or more safety members traversing a path outward of the flight rotor so that an object approaching the flight rotor through the path contacts one of the safety members before contacting the flight rotor, wherein the safety rotor decelerates when one of the safety members contacts an object; a sensor for detecting rotation of the safety rotor; and a controller configured to: determine, using the sensor, a deceleration of the safety rotor corresponding to one of the safety members contacting an object; and cause the rotation of the flight rotor to cease in response to detecting the deceleration of the safety rotor.
US11027830B2	Center biased actuator A center biased actuator having an outer cylinder, a slave cylinder linearly transposed within the outer cylinder, a rod assembly with a piston linearly transposed within the slave cylinder and a rod extending from the outer cylinder, one or more first dynamic seals arranged to act on a sidewall of the rod to inhibit hydraulic fluid leaking from the outer cylinder, one or more second dynamic seals arranged to act on a sidewall of the slave cylinder or an inner surface of the outer cylinder to inhibit hydraulic fluid leaking from the outer cylinder, and a gas chamber comprising a sealed expandable chamber containing gas. The expandable chamber is arranged to act on hydraulic fluid within the center biased actuator to bias the center biased actuator to assume an intermediate condition which lies between a compressed condition and an extended condition.
US11027820B2	Wing comprising a leading edge slat and having means for preventing the transition to a turbulent boundary layer A wing comprising a fixed main part and a leading edge slat with upper and lower surface rear edges. The wing main part has an upper surface wall, which extends downstream and in alignment with the upper surface rear edge, and a lower surface wall, which extends downstream and in alignment with the lower surface rear edge. The wing has an upper surface gap between the end of the upper surface rear edge and the end of the upper surface wall and a lower surface gap between the end of the lower surface rear edge and the end of the lower surface wall. The wing has an upper surface channel downstream of the upper surface gap and a lower surface channel downstream of the lower surface gap. The wing comprises a suction system connected to each channel and arranged to suck the air contained in the channel.
US11027819B2	Method and a control unit for controlling actuation of a foldable wing tip section of a wing of an aircraft A method to control folding of a wing tip section about a fixed base wing section by a control system that automatically determines whether: (i) a command signal is received to fold the wing tip section, (ii) a first condition indicating signal indicates that the aircraft is on the ground; (iii) the current speed of the aircraft is no greater than a preset maximum speed, and (iv) the aircraft is not at gate in an airport.
US11027816B1	Air-buoyant structures and vehicles Air-buoyant structures, and vehicles incorporating air-buoyant structures, are provided. Hollow, air-buoyant structures may include a shell of ultra-low density aerogel material, foam material, or vapor-expanded material that is strong and stiff enough to withstand atmospheric pressure and lightweight enough to achieve buoyancy in air under evacuation. The shell may be reinforced with a suitable reinforcing material, such as helical nanofibers. The air-buoyant structures may also include vacuum pumps and valves operably connected to or integrated with the hollow shell. The vacuum pumps and valves may be configured to pump air out of the hollow shell and allow air back into the hollow shell to control buoyancy.
US11027811B2	Outboard motor lifting device An outboard motor lifting device includes a hydraulic source, a first oil channel connecting the hydraulic source with a second chamber of a tilt cylinder, a second oil channel connecting the first oil channel with a second chamber of a trim cylinder, a third oil channel connecting the hydraulic source with a first chamber of the tilt cylinder, a check valve provided between the second chamber of the tilt cylinder and a connection position between the first and second oil channels, a fourth oil channel connected to the third oil channel, and a switch valve provided on the second oil channel and connected with the fourth oil channel. The switch valve has a connection state where communication between the first oil channel and the second chamber of the trim cylinder is closed, and communication between the fourth oil channel and the second chamber of the trim cylinder is open.
US11027810B2	Float for connection to a swimmer in a wave powered vehicle A float (1) suitable for use as a buoy or as a component for a wave-powered vehicle. The float (1) includes an upper member (12) whose height can be changed and/or which remained substantially vertical even when the float is in wave-bearing water. A low drag cable (2) suitable for use as a tether in a wave-powered vehicle has a streamlined cross-section and includes a tensile member (21) near the front of the cross-section, at least one non-load-bearing member (22) behind the tensile member, and a polymeric jacket (23). Wave-powered vehicles having a float (1), a submerged swimmer (3) and a tether (2) connecting the float and the swimmer, include a means for determining whether the tether is twisted; or a means (91) for untwisting the tether; or a pressure-sensitive connection (71, 72, 73) which can disconnect the tether when the vehicle is dragged downwards by entanglement with a whale; or a 2-axis universal joint securing the tether to the float or to the swimmer; or elastic elements which absorb snap loads created by the tether; or two or more of these.
US11027809B2	Sailing vessel Embodiments described herein relate generally to a sailing vessel that can substantially obviate the heeling problem experienced by classical sailboats. During navigation, the sailing vessel is driven forward by an aerodynamic force exerted by wind on the sail, and balanced by a hydrodynamic force exerted by water on a float on the stern of the sailing vessel, the aerodynamic force and the hydrodynamic force being parallel or substantially parallel to a longitudinal axis of the sailing vessel.
US11027808B2	Aerofoil sail An aerofoil sail (30) for providing motive power to a waterborne vessel, the sail comprising a leading aerofoil portion (35a) and a trailing aerofoil portion (35b), and the sail comprising a spar (32), at least one of the aerofoil portions rotatably positionable, and the sail comprising a controller to control individually the angular position of at least one of the aerofoil portions relative to the spar, and the spar rotationally positionable about its longitudinal axis.
US11027806B2	Towed body with foiled depressor Apparatus and methods are disclosed relating to a body towable behind a vessel in a body of water, an arm rotatably coupled to the body, and one or more foils disposed on the arm. The arm, when deployed, is configured to be free to rotate as the apparatus is towed through the body of water. The one or more foils are configured to generate lift as the apparatus is towed. Due to the free rotation of the arm, the foils impart tension force to the body and not torque forces.
US11027804B2	Underwater sailing body and method of controlling posture of underwater sailing body An underwater sailing body includes: a positioning device configured to detect positional information of a hull of the underwater sailing body; a posture detecting sensor configured to detect posture information of the hull; an actuator configured to apply thrust to the hull in a front-rear direction of the hull, a left-right direction of the hull, an upper-lower direction of the hull in water to change the position and posture of the hull; and a controller configured to control the actuator. In order to hold a hull at a target position when the hull receives an external force by disturbances, the hull keeps balance by using thrusters with respect to the external force acting on the hull. Specifically, the hull is held at the target position by controlling a thruster configured to generate thrust in a front-rear direction and a thruster configured to generate thrust in a left-right direction.
US11027801B2	Boat lift A boat lift has one or more pumps that evacuate water from a first flotation tank construct and a second flotation tank construct to create flotation of the boat lift. Modular boat lifts may be constructed according to the invention that have substantial size but are transportable by truck for construction on site.
US11027799B2	Systems and methods for 3-dimensional scanning for drydocking A method comprising scanning at least one portion a hull of a vessel positioned below a waterline while the vessel is floating in water. The method further comprises generating multi-dimensional scans of the at least one portion of the hull based on data acquired during the scanning, generating a 3-dimensional (3D) model of the at least one portion of the hull, analyzing the 3D model to identify one or more features of the hull of the vessel below the waterline, generating docking information for drydocking the vessel based on the one or more features of the hull, and identifying, based on the generated docking information, a docking plan for supporting the vessel when the vessel is supported out of the water. The method further comprises outputting instructions to dry dock the vessel.
US11027797B1	Personal watercraft A personal watercraft includes: a watercraft body made of a resin; a handle projecting upward from the watercraft body; a meter display device disposed above the watercraft body and forward of the handle; a meter cover made of a resin and covering a space from above, the space being adjacent to and forward of the meter display device and being in contact with an upper surface of the watercraft body and a forward surface of the meter display device; and an antenna disposed in the space.
US11027793B2	Multi-speed drive hub for bicycle A multi-speed drive hub for a bicycle contains: a hub shaft, a speed-changing transmission, a speed shifter, and a sprocket set. The hub shaft is connected on a center of a wheel rim of the bicycle and includes a speed-changing transmission. The speed-changing transmission includes at least one drive element and an actuator for driving multiple force segments of the speed-changing transmission to rotate reciprocately. The speed shifter includes a fitting sleeve which has a third fixing orifice corresponding to the at least one drive element. The sprocket set includes multiple speed cassettes of different diameters and includes multiple spacing spaces, each of which is defined any two adjacent speed cassettes. The fitting sleeve has multiple ribs and multiple flexible sheets. Each drive elements includes multiple retainers, multiple columns, and multiple force segments.
US11027791B1	Universal motorcycle storage case mounting assembly A universal motorcycle storage case mounting assembly that detachably secures to a motorcycle or other vehicle, allowing a user to safely transport personal belongings to a destination. The mounting assembly utilizes two main components a base frame and a platform, with a storage case being couplable to the platform, forming a transportable storage case. In order to secure to a motorcycle or other vehicle, the mounting assembly utilizes a triple-locking system, including a base latch bracket that attaches to the motorcycle; a receipt on the platform; and a platform latch bracket, the receipt and the platform latch bracket configured to secure the platform to the base frame. As a result of the locking system, the storage case requires force to detach from the motorcycle, thereby preventing inadvertent detachment. Upon arrival at a destination, a rider can detach the transportable storage case, rather than leave belongings on the motorcycle.
US11027790B2	Adaptive lighting system A lighting system for a vehicle at least one primary low beam element at least a first adaptive element, a second adaptive element and a third adaptive element and a lean angle sensor generating a lean angle signal. A controller controls the plurality of adaptive elements so that the first element, the second element and third element are extinguished at less than a first lean angle, between the first and a second lean angle greater than the first lean angle illuminating the first adaptive element, between the second and a third lean angle greater than the second lean angle illuminating the first and second adaptive elements, between the third lean angle and a fourth lean angle greater than the third lean angle illuminating the second adaptive element and the third adaptive element and extinguishing the first adaptive element in response to the lean angle signal.
US11027789B2	Blocking key for a wiper linkage, linkage sub assembly, and linkage comprising a blocking key; method for installing a blocking key on a wiper linkage The present invention concerns a key (1) for locking a link including a U-section and a crank of a linkage of a wiper mechanism in a transport position, characterized in that it comprises: a shaft (11) having at one end a radial holding excrescence (13) and at the other end an enlarged head (15) intended to cooperate with a hollow part of the U-section forming the link, and a first radial finger (17) configured to be housed in a slot for locking the link in the transport position.
US11027787B2	Attachment assembly for use with a work machine Attachment assembly for use with a work machine. The attachment assembly includes an attachment adapter and an attachment frame. The attachment adapter is coupled to the work machine and fixed relative thereto. The attachment frame includes a member that defines an attachment point. The attachment point engages, into an engaged mode, with the attachment adapter when a front suspension system of the work machine is raised to a raised position. The attachment point disengages, into a disengaged mode, from the attachment adapter when the front suspension system is lowered to a lowered position. The attachment adapter travels with the work machine when in the engaged mode and also in the disengaged mode. The attachment frame travels with the work machine only when in the engaged mode.
US11027786B2	Gyroscopic rider assist device A tilting vehicle includes a frame and a front wheel coupled to the frame. A rear wheel is coupled to the frame and positioned rearward of the front wheel in a longitudinal direction. A seating area includes at least one seat positioned to support a rider between the front wheel and the rear wheel. A gyroscopic rider assist device is provided within an enclosure behind the seating area and above the rear wheel.
US11027783B1	Joint between sidewall and roof panel of trailer A trailer includes a vertically-oriented sidewall, a horizontally-oriented roof panel disposed above the sidewall, and a top rail attached to the sidewall. At least a section of the top rail is disposed above the sidewall and below the roof panel. A substantially L-shaped cove has a horizontal leg attached to a lower surface of the roof panel, and a vertical leg attached to an inner surface of the sidewall. A board of thermal insulation includes an upper portion and a lower portion. The upper portion is disposed between the vertical leg of the cove and the section of the top rail, and the lower portion is disposed between the vertical leg of the cove and the sidewall.
US11027779B2	Front vehicle body structure A front vehicle body structure includes a sub-frame. The sub-frame includes left and right longitudinal frames which extend in a longitudinal direction of a vehicle body and a horizontal frame which connects rear portions of the left and right longitudinal frames. The left longitudinal frame includes a steel frame and a light metal frame. A rear member of the steel frame overlaps the light metal frame in a vertical direction and is joined to the light metal frame. The left longitudinal frame includes a bent portion. The bent portion is provided on the front side of the vehicle body with respect to a front end portion of the light metal frame.
US11027774B2	Actuator for steering system Provided is an actuator for a steering system, which can be increased in degree of freedom for design change, regardless of a configuration change of a hydraulic power steering side. The actuator for a steering system comprises a transmission mechanism configured to transmit the rotation of a steering shaft to a steered wheel, a piston disposed in the transmission mechanism, and a pair of pressure chambers configured to generate a force acting to move the piston. The actuator for a steering system is disposed between a hydraulic power steering system, which imparts a steering force to the steered wheel along with the movement of the piston, and a steering wheel. The actuator for a steering system includes an input shaft which is rotatably and axially supported by the housing and disposed in the steering wheel side; an output shaft which is rotatably and axially supported by the housing and disposed in the hydraulic power steering system; a torsion bar connecting the input shaft and the output shaft; a motor rotor disposed around the outer periphery of the output shaft within the housing and configured to rotate integrally with the output shaft; a motor stator disposed around the outer periphery of the motor rotor within the housing; and a rotation angle detecting section disposed within the housing and configured to detect the rotation angles of the input and output shafts or a relative angle of the input and output shafts.
US11027763B2	Cart of telescopic structure Disclosed is a cart of a telescopic structure, comprising: a telescopic rod; a telescopic tube, where at least one of the telescopic tube and the telescopic rod have a hollow structure acting as an accommodation space that is required when the telescopic tube and the telescopic rod collapse into each other; a linkage mechanism connected to one end of the telescopic tube that is away from the hollow structure, and connected to one end of the telescopic rod that is close to the hollow structure; and a frame connected to the linkage mechanism. When the frame is rotated with respect to the linkage mechanism and collapses, the telescopic tube is also rotated with respect to the linkage mechanism, and one of the telescopic tube and the telescopic rod is retracted into the other thereof by means of the linkage mechanism.
US11027754B2	Cable or similar transport installation, and vehicle suitable for such installation A transport installation includes a traction member extending in a circuit and associated with an external power source so as to be moved along the circuit, a vehicle having a power storage system, a motor system, a generator system and a fixed support adjacent to the circuit. The generator system of the vehicle includes a generator that may be activated to supply power to the storage system when the vehicle is coupled to the traction member and driven along the circuit by the traction member. The motor system of the vehicle includes a motor that may be activated to receive power from the storage system and move the vehicle relative to the fixed support.
US11027752B2	Railway facility with high throughput loop track A railway facility with high throughput loop track includes a series of adjacent parallel staging tracks connected to a main line to receive and depart trains, arranged in a path so that trains transverse around the railway facility. A balloon loop track, which includes a loading or unloading facility, is connected to the staging tracks loops and reverses the direction of the train so that upon completion of loading or unloading a train can depart or be re-staged without requiring repositioning or turning of locomotives. Staging tracks are included for staging both arriving and departing trains. In alternative embodiments transload tracks and at-grade access roads allow storage and retrieval of cargo to interior space within the staging tracks, and an escape track allows expedited exit of trains from the balloon loop track.
US11027749B2	Information presentation apparatus, steering apparatus, and information presentation method An information presentation apparatus includes an acquisition unit, an asymmetric acceleration generating unit, and a signal generating unit. The acquisition unit acquires at least one of information inside a vehicle or information outside the vehicle. The asymmetric acceleration generating unit presents haptic feedback information to a user via a steering unit provided in the vehicle by generating asymmetric acceleration. The signal generating unit generates a driving signal on the basis of information acquired by the acquisition unit and send the driving signal to the asymmetric acceleration generating unit.
US11027747B2	Vehicle content based symbiosis for vehicle occupants Vehicle event processing includes vehicle event detection, notification and/or action response processing. Information relating to a vehicle event is automatically distributed among a plurality of occupants of a vehicle. The plurality of occupants includes a driver of the vehicle and one or more passengers of the vehicle. Based on at least a portion of the information distributed and a perspective of at least one passenger of the one or more passengers, at least one tracking component of the vehicle is adjusted. Based on the adjusting, additional information is obtained. Based on at least a portion of the additional information, an action is automatically taken.
US11027746B2	Drive mode switching control device, method and program A driver state determination unit of a drive mode switching control device regularly or irregularly determines whether a driver's state is a state of being able to perform a driving operation in a manual drive mode. The drive mode switching control device determines whether an operation performed by the driver is an emergency override operation or a non-emergency override operation. The drive mode switching control device outputs a switching signal for switching an automatic drive mode to the manual drive mode when a determination result by the driver state determination unit immediately before detection of the emergency override operation is that a driver's state is a state of being able to perform a driving operation in the manual drive mode.
US11027745B2	Indirect vehicle parametrization via user profiles A method and corresponding device are provided for setting configurable parameters of a system, for example a vehicle. The method is used to establish a user-specific value of a system parameter of the system. The method determines a user profile of a user. The user profile includes user-specific values of one or more user parameters which describe one or more properties of the user of the system. The method prepares a mapping function which maps different values of the one or more user parameters of the user profile onto different values of the system parameters. The method determines the user-specific value of the system parameter for the user, on the basis of the user profile of the user and on the basis of the mapping function.
US11027742B1	Traffic based driving analysis A driving analysis server may be configured to receive vehicle operation data from vehicle sensors and telematics devices of a first vehicle, and may use the data to identify a potentially high-risk or unsafe driving behavior by the first vehicle. The driving analysis server also may retrieve corresponding vehicle operation data from one or more other vehicles, and may compare the potentially high-risk or unsafe driving behavior of the first vehicle to corresponding driving behaviors in the other vehicles. A driver score for the first vehicle may be calculated or adjusted based on the comparison of the driving behavior in the first vehicle to the corresponding driving behaviors in the other vehicles.
US11027739B2	Method and control device for operating a power takeoff A method for operating an auxiliary power take-off (5) in a drive-train of a motor vehicle with at least a drive aggregate (1) and with a transmission (2) connected between the drive aggregate (1) and an axle drive (4). To operate the power take-off (5,) a transmission gear is engaged in the transmission (2). During an uninterrupted operation of the power take-off (5), after lapse of a defined time period, an automatic shift to a protective gear is carried out in the transmission (2).
US11027738B2	Systems and methods for response vehicle pump control A vehicle includes an engine, a transmission coupled to the engine, a pumping system selectively coupled to the engine by the transmission, and a controller. The pumping system is configured to receive an inlet flow of water from a water source. The controller is configured to receive an indication regarding a pressure of the inlet flow of water and transmit a control signal to the transmission to change a gear of the transmission based on the indication regarding the pressure of the inlet flow of water.
US11027737B2	Travel control apparatus and travel control method A travel control apparatus is provided. The travel control apparatus includes: a travel control unit that controls the travel of the vehicle in the control state of one of the manual travel control state and the automatic travel control state in accordance with a selection by the driver; a concentration disturbing matter detection unit that detects an occurrence of a predetermined concentration disturbing matter set as a matter which disturbs a concentration of the driver with respect to the driving operation; and a control state switching unit that switches the control state from the manual travel control state to the automatic travel control state when the occurrence of the concentration disturbing matter is detected while the control state is the manual travel control state.
US11027736B2	Systems and methods for anticipatory lane change An anticipatory lane change system is described for assisting a host vehicle positioned in a current lane that is adjacent an adjacent lane. The anticipatory lane change system may include an identification module that identifies a potential lane change location and receives proximate vehicle data associated with proximate vehicles. The anticipatory lane change system may include a prediction module that predicts future kinematic data at a future time for a set of the proximate vehicles. The anticipatory lane change system may include a determination module that determines whether a gap will be available at the potential lane change location at the future time based on the future kinematic data. The anticipatory lane change system may include a lane change module that initiates a lane change maneuver for the host vehicle in response to determining that the gap will be available at the potential lane change location at the future time.
US11027731B2	Launch control method for hybrid vehicle A launch control method for a hybrid vehicle includes: determining an intent of a driver to execute a launch control mode in a state in which an engine is turned-off; when the intent of the driver is to execute the launch control mode, starting the engine and controlling an engine speed; performing a slip control on a slip element of a transmission input terminal; when the engine speed is synchronized with a motor speed or a difference between the engine speed and the motor speed is less than a predetermined range, locking up an engine clutch; when the engine clutch is locked up, performing an engine pre-boosting control to raise an engine torque to a torque at which battery charging is available due to a motor; performing a take-up control on the slip element; and when the take-up control is terminated, locking up the slip element.
US11027728B2	Vehicle control device An integrated object formation unit of a vehicle control device forms integrated objects, which are integral objects, the boundaries of the integrated objects being determined from the positional relationship between two or ore objects in a prescribed distance range. An interference prediction unit of the vehicle control device predicts the probability of the integrated objects, instead of each of the objects, coming into contact with, or near, a vehicle.
US11027727B2	Apparatus for responding to vehicle water splashing, system having the same and method thereof An apparatus for responding to vehicle water splashing includes a processor determining the vehicle water splashing based on image data of a nearby vehicle and determining dangerousness caused by the vehicle water splashing to perform vehicle control and storage storing information determined by the processor and the image data of the nearby vehicle.
US11027724B2	Parking assistance system and parking assistance method The present disclosure relates to a parking assistance system for searching for a parking space and parking a vehicle in the parking space, which includes: a determinator configured to determine whether or not the vehicle is in a stopped state based on movement information of the vehicle; a calculator configured to calculate inclination information, which is an inclination of the vehicle or road surface on which the vehicle is located, using an inclination sensor included in the vehicle; a memory configured to store traveling information including first inclination information when the first inclination information calculated by the calculator is less than predetermined threshold inclination information in a parking space searching step, and configured to maintain the first inclination information or update the traveling information by changing the first inclination information into second inclination information based on at least one of a stopped time during which the vehicle remains stopped and the second inclination information measured during the stopped time in a parking step in which parking is processed; and a controller configured to control the vehicle to move toward the parking space based on the traveling information stored in the memory.
US11027722B2	Yeilding action assistance system A yielding action assistance system for assisting a vehicle driver to take an appropriate action in yielding to a passing emergency vehicle. The yielding action assistance system comprises: a detector that detects a proximity of the emergency vehicle; an information collector that collects a road information and information about the emergency vehicle and other vehicle; a target zone determiner that sets and updates a target zone to pull over the vehicle based on the information about the other vehicle and the road; and a notifier that informs a driver about the target zone.
US11027720B2	Hybrid vehicle A hybrid vehicle includes an engine; a motor generator; and an electronic control unit to control the engine and the motor generator. Further, when an engine speed thereof is increased, the electronic control unit calculates an engine torque by adding an engine inertia torque to a request engine torque and cause the engine to output the calculated engine torque, and cause the motor generator to output a reaction torque in response to the request engine torque, and the electronic control unit performs control so that a torque assistance amount exerted by the motor generator is changeable while the engine speed is increased.
US11027714B2	Brake apparatus for vehicle A brake apparatus for a vehicle may including: a cylinder including a supply flow path to supply working fluid of a reservoir and a hydraulic chamber connected to the supply flow path; a piston movably installed in the cylinder, and connected to a brake pedal; an elastic member installed in the hydraulic chamber so as to elastically support the piston; a sealing member installed on the outer surface of the piston so as to be in contact with the inner surface of the hydraulic chamber; and a communication flow path formed on the inner surface of the cylinder along the longitudinal direction of the cylinder, and guiding the working fluid of the hydraulic chamber to the opposite side of the moving direction of the piston, when the piston is moved.
US11027713B2	Brake NVH countermeasure Systems and methods are described for controlling a vehicle braking system. An electronic controller determines a target deceleration based at least in part on a detected displacement position of a brake pedal and determines an adjusted braking pressure to be applied to at least one wheel of the vehicle such that, regardless of the displacement position of the brake pedal and the target deceleration, the adjusted braking pressure is maintained outside of a defined range of braking pressures that corresponds to a NVH condition for the at least one wheel. The adjusted braking pressure is then applied to the at least one wheel of the vehicle.
US11027711B2	Anti-lock brake control device The anti-lock brake control device includes: a wheel motion estimator to estimate one or more of an angle, an angular velocity, and an angular acceleration of a wheel; a slip estimator to estimate a slip state of the wheel, using an estimation result of the wheel motion estimator; and an anti-lock controller to give a command for causing a brake device to reduce a braking force, in accordance with the estimated slip state of the wheel. The slip estimator includes delay compensators, such as one or a plurality of filters, which perform delay compensation for the estimation result of the wheel motion estimator. The anti-lock controller gives the command for reducing the braking force, on the basis of a result of predetermined determination including comparison of the plurality of estimation results outputted from the slip estimator.
US11027710B2	Emergency braking system for a vehicle and method for controlling the emergency braking system An emergency braking system for a vehicle includes an emergency braking control unit configured to control the emergency braking system according to a first parameter set. The first parameter set is selected by the emergency braking control unit from a plurality of parameter sets. Each respective parameter set of the plurality of parameter sets is associated with a respective vehicle variant and adapts the emergency braking system to the respective vehicle variant. Each respective vehicle variant is characterized by a design of a braking system of the respective vehicle variant for adapting the emergency braking system of the respective vehicle variant to the design of the braking system of the vehicle variant. The first parameter set is associated with a first vehicle variant that characterizes the vehicle.
US11027708B2	Pedal assembly with a release mechanism Embodiments described herein are directed to a pedal assembly. The pedal assembly includes a housing, a pedal arm, a retaining member, and a block. The pedal arm has an upper end. The upper end is pivotally coupled to the housing. The retaining member is slidably engaged within the housing. The retaining member has a first angled portion. A portion of the retaining member in communication with the upper end of the pedal arm. The block is slidably mounted within the housing and perpendicular to the first angled portion of the retaining member. The block has a second angled portion that is complimentary to the first angled portion. Upon an impact, the second angled portion slidably engages with the first angled portion, which causes the retaining member to move and release the upper end of the pedal arm from the housing.
US11027706B2	Apparatus and method for applying wiping water onto a vehicle window A wiper system to apply wiper fluid to a vehicle window includes at least one wiper arm, at least one sensor, and at least one control apparatus. The sensor is configured to detect, during a wiping operation, the wiper arm in at least one defined position in a wiping area of the wiper arm, and to send a detection signal to the control apparatus.
US11027704B2	Wiper blade assembly Disclosed herein is a wiper blade assembly including: a contact member; an elastic member for supporting the contact member; a cover member for covering the elastic member; and a coupling cover to be fastened to the elastic member. The cover member includes: a spoiler; an extended plate extended from one end of the spoiler; a first coupling protrusion located in a first predetermined position of the extended plate; and a first coupling hole located in a second predetermined position of the extended plate adjacent to the first coupling protrusion. The coupling cover includes: a second coupling hole located in an inner space thereunder and receiving the first coupling protrusion of the cover member; and a second coupling protrusion located adjacent to the second coupling hole and inserted into the first coupling hole of the cover member. The cover member can be reliably fixed to the wiper blade assembly.
US11027699B2	Backup key with wireless capabilities A keycard may include electronics to allow access to vehicle functions. A keycard system for a vehicle includes a plurality of sections of a stacking key, and a keycard, including a key holder defining a plurality of sleeves, each sleeve having an opening for receiving a respective one of the plurality of sections, wherein the key holder further includes electronics configured to wirelessly provide access to the vehicle. A foldable keycard includes hinged sections, each defining a base and a layer of a blade of a key extending therefrom; and an electronic vehicle access component arranged at the base of one of the sections opposite the blades, and configured to fold away from the blades to allow the keycard to be inserted into a lock.
US11027697B2	System, method, and apparatus to mitigate and or prevent autonomous vehicle misuse through the use of security enabled sensors Methods and systems for implementing autonomous vehicle security features. The present invention details an effective and secure methodology to implement the external management and control of autonomous vehicles by authorized personnel, usually law enforcement, through the use of intelligent sensors that can override an autonomous vehicle controller's functionality as necessary.
US11027695B2	Belt retractor having a second force limiter The invention relates to a belt retractor comprising a frame (10), a belt reel (12) rotatably arranged within the frame, a blocking mechanism (18) by which the belt reel (12) can be blocked within the frame (10), and a load limiter (14) which is detachably coupled to the belt reel (12), characterized in that for coupling the load limiter (14) at least one load-transmitting bar (28) is used which is arranged at the belt reel (12) and is retained in a coupling position by a support ring (32), wherein the support ring (32) can be moved from a supporting position to a release position by means of an actor (70).
US11027694B2	Seatbelt pretensioner assembly A seatbelt pretensioner assembly includes a body. The seatbelt pretensioner assembly includes a shaft rotatably supported by the body. The seatbelt pretensioner assembly includes a spring operatively engaged between the body and the shaft. The seatbelt pretensioner assembly includes a solenoid supported by the body and movable between a first position inhibiting rotation of the shaft relative to the body and a second position permitting rotation of the shaft relative to the body.
US11027692B2	Air bag device An air bag device has an inflator and a bag unit configured to be deployed on a front part of a vehicle body with a gas supplied from the inflator. The bag unit includes a first bag, a second bag, and a connector, which are annularly connected to one another, and when the bag unit is deployed, the first bag and the second bag are erected on the vehicle body into a mountain-like shape in such a way that the bag unit forms a substantially triangular shape as a whole.
US11027691B2	Airbag An airbag includes a body and a redirecting cloth that is composed of a sheet material having flexibility and disposed inside the body. The redirecting cloth includes an inlet port for taking in an inflation gas; one or more outlet ports that release the inflation gas as flown from the inlet port towards predetermined regions of the body; and a sew region that sews first and second terminal edges of the sheet material together. Each of the first and second terminal edges of the sheet material includes a turned-and-sewn region that has been turned inward and sewn. At least a part of the sew region is formed by sewing terminals of the turned-and-sewn regions together.
US11027688B2	Systems and methods to support an inflatable airbag cushion Inflatable airbag assemblies are disclosed that include an inflatable airbag cushion that deploys rearward from an instrument panel and forward of a vehicle seating position and that include a forward-facing surface configured with a forward protrusion to engage a blind hole of an instrument panel, or a blind end of blind hole of the instrument panel, or blind hole of the instrument panel comprising a shelf.
US11027687B2	Steering wheel A steering wheel having a steering wheel body (10) having a first force transmitting component, and a horn actuation element. The horn actuation element having a horn actuation surface (23) and having a second force transmitting component. A load cell (30) is provided having a sensitive element that changes at least one of its electrical properties in response to a compression force. The sensitive element placed between the first and second force transmitting components. At least one elastically deformable element is provided between the steering wheel body (10) and the horn actuation element. When a pushing force is applied to the horn actuation surface (23) the force applied to the sensitive element changes. In a resting state of the steering wheel a compression force is applied to the sensitive element by the first and second force transmitting components by a preload and in that the compression force applied to the sensitive element is reduced when a pushing force is applied to the horn actuation surface (23).
US11027680B2	Vehicle tracks A vehicle includes a track that defines a guide channel, first and second transmitters positioned on first and second sides of the guide channel, respectively, and a bridge that extends over an upper portion of the track to cover the guide channel when the bridge is in a closed position.
US11027678B2	On-board system and detector hub An on-board system includes: a plurality of detectors provided to a vehicle; a controller configured to control an on-board instrument mounted on the vehicle based on detection information indicating a result of detection by each of the detectors; a detector hub interposed between each of the detectors and the controller in an intercommunicatable manner and configured to collect the detection information obtained by the detectors and transmit the collected detection information to the controller; a first network connecting the on-board instrument and the controller in an intercommunicatable manner; and a second network independent from the first network and connecting the detectors, the detector hub, and the controller in an intercommunicatable manner. As a result, the on-board system and the detector hub can achieve appropriate communication.
US11027677B2	Camera based activation of heated wipers and windshield defrost A method to automatically activate at least one cold weather feature of a vehicle includes determining if the vehicle is in a state for activating at least one cold weather feature, and then determining at least one cold weather condition exists for activating at least one cold weather feature. When it is determined that at least one cold weather condition exists the at least one cold weather feature is automatically activated.
US11027664B2	Rearview monitor apparatus A rearview monitor apparatus includes: a display provided on an instrument panel; and a housing formed to surround a periphery of the display, wherein the housing includes an upper surface arranged above the display, a side surface arranged at the outside in a vehicle width direction of the display, and a visor that extends in a vehicle rearward direction beyond the display from vehicle rearward positions of the upper surface and the side surface and that forms an opening part in a vehicle rearward direction, and a first recess part of which a depth gradually increases toward a vehicle frontward direction towards the inside in the vehicle width direction from an outer end in the vehicle width direction is formed on the upper surface side of the visor.
US11027662B2	Support rack A cargo and storage rack for increasing the carrying capacity of a vehicle having a spare tire mount on the exterior of the vehicle. Retaining features of a mounting boss engage the retainment features of the spare tire to the spare tire mount. The mounting boss is adapted to receive storage brackets above or below or both of above and below the mounting boss, to secure cargo securing features at desired distances of engagement from the boss. Rails of any bracket secured to the boss provide support for alternately translating and selectably locatable cargo supporting features, such that the rack can secure cargo without a bracket that provides its own securing features. Optionally, the rack can support cargo with any combination of selectably locatable cargo supporting features on the rails and a bracket, and the rack comprises methods of construction and customization that facilitate rapid reconstruction of the rack and removal from the vehicle.
US11027661B2	Extendable crossbar for a vehicle A roof rack system for affixing to a vehicle having a plurality of mounting locations system is provided. The roof rack system comprises a crossbar assembly comprising: an axis of motion, e.g., translational motion; an internal structure; a first section; a second section; a third section; a first end mount; and a second end mount. The first and second sections are configured to translate, in opposite directions, along the axis of motion relative to the internal structure. The internal structure is configured to cause the third section to be centered between the first and second sections as the first and second sections translate. The first and second end mounts are coupled to respective outboard portions of the first and second sections. The first and second end mounts are configured to mount to respective first and second mounting locations, e.g., mounting locations of the vehicle.
US11027658B2	Lamp for vehicle A lamp for vehicle includes a light source unit including a light source and a light guide unit which emits light incident from the light source to form an image having a predetermined shape; a lamp assembly including a lamp housing and a lens unit coupled to the lamp housing to form a space for accommodating the light source unit and a plurality of lamp components; and a position fixing unit formed on one side in the lamp assembly to fix a position of the light source unit. The position fixing unit comprises a first contact portion that contacts at least a portion of a lower surface of the light guide unit; and a second contact portion that contacts at least a portion of an upper surface of the light guide unit.
US11027653B2	Apparatus, system and method for preventing collision The present disclosure is provided to a collision avoidance apparatus, system and method, configured to calculate a velocity vector of a following vehicle located behind the vehicle in the driving lane in which the vehicle is driving based on at least one of the image data and the sensing data, calculate a collision risk range between the vehicle with the following vehicle based on the driving data and the velocity vector, calculate a time to collision within the collision risk range, and output a warning based on the time to collision. According to the present disclosure, warning and control may be performed according to the collision risk range and the time to collision calculated using the velocity vector of the following vehicle, thereby preventing collision with an adjacent following vehicle.
US11027652B2	Vehicle collision avoidance system A vehicle collision avoidance system has a side-view camera positioned on a side portion of a vehicle and configured to present a driver with a rear side view exterior to the vehicle. A display is coupled to the side-view camera and disposed in view of the driver to output a video stream from the side-view camera. A turn signal sensor is configured to detect activation of a turn signal. A controller is configured to receive signals from the turn signal sensor and to adjust a field of view of the side-view camera based on activation of the turn signal.
US11027650B2	Method and apparatus for improving operation of a motor vehicle A device includes a microprocessor and a computer readable medium coupled to the microprocessor. The computer readable medium includes instructions stored thereon that cause the microprocessor to receive output from at least one sensor monitoring a travel context of a vehicle and determine, based on the output received, a condition of the vehicle. The instructions cause the microprocessor to determine, based on the determined condition of the vehicle, modified driving operations to improve the operation of the vehicle. The instructions cause the microprocessor to construct a message describing the determined modified driving operations and communicate one or more modified driving operations to an operator for potential implementation.
US11027648B2	Dynamic sound emission for vehicles A vehicle computing system may implement techniques to dynamically adjust a volume and/or frequency of a sound emitted from a vehicle to warn an object (e.g., dynamic object) of a potential conflict with the vehicle. The techniques may include determining a baseline noise level and/or frequencies proximate to the object. The baseline noise level and/or frequencies may be determined based on an identification of one or more noise generating objects in the environment. The vehicle computing system may determine the volume and/or a frequency of the sound based in part on the baseline noise level and/or frequencies, an urgency of the warning, a probability of conflict between the vehicle and the object, a speed of the object, etc.
US11027647B2	Embossed smart functional premium natural leather A smart functional leather assembly includes a leather substrate, an electronic circuit layer including one or more conductive traces and optional electronic elements arranged on the leather substrate, optionally a pigmented coating arranged on the circuit layer, and an optional anti-soiling layer arranged on the pigmented layer. The entire smart functional leather assembly, including the circuit, are embossed to provide an embossed smart functional leather assembly with an embossed pattern.
US11027637B2	Vehicle seat To improve the seated feeling of an occupant in a seat having partially different hardness, a vehicle seat includes a seat frame, an S spring which is installed on the seat frame and receives a load of an occupant, and a seat back pad which has a plurality of regions respectively formed of different materials and is disposed between a skin material of the seat and the S spring. The S spring is disposed at a position facing a boundary portion which is provided in the seat back pad and is the plurality of regions respectively formed of different materials.
US11027631B2	Vehicle seat A vehicle seat includes a seat frame including a pan frame (12), a blower, and a bracket (50) configured to attach the blower to the pan frame (12). The bracket (50) is provided with a first engagement portion (110) protruding toward the pan frame (12), and the pan frame (12) is provided with a first engagement hole (12A) in which the first engagement portion (110) is engageable. The first engagement portion (110) includes a first stopper portion (112) configured to be locked to the pan frame (12) when the first engagement portion (110) is engaged in the first engagement hole (12A), and a first elastically deformable portion (113) configured to deform elastically to allow the first stopper portion (112) to pass through the first engagement hole (12A) when the first engagement portion (110) is inserted into the first engagement hole (12A).
US11027628B2	Vehicle having rail-mounted components A vehicle includes a cabin and a track assembly. The track assembly is coupled to a portion of the cabin. The track assembly includes a rail assembly. The rail assembly defines an interior aperture. The interior aperture is inaccessible from a top side, a first lateral side, and a second lateral side of the rail assembly. The rail assembly defines a first external channel in the first lateral side and a second external channel in the second lateral side. The first and second external channels receive a carriage power conductor and a carriage data conductor, respectively.
US11027625B2	Battery charging control method and system A battery charging control method includes receiving a destination input to a navigation device. When a vehicle starts, a switch is turned on to charge a battery. When a State Of Charge (SOC) of the battery becomes larger than a preconfigured value, the switch is turned off for a first time interval derived on the basis of an estimated destination arrival time derived from the navigation device. The switch is turned on again at a time point at which the first time interval has passed. The switch i turned on again to charge the battery for a second time interval.
US11027624B2	Electric vehicle charging by adjusting charger current based on battery chemistry A method for charging an electric vehicle using charge current from a charging source. The charge current is determined based at least on the state of charge of the electric vehicle and a chemistry or type of the battery system.
US11027622B2	Performing actions associated with a connected vehicle Systems and methods for collecting data from electric vehicles, and performing various different actions based on the collected data, are described. In some embodiments, a device, such as a remote device that communicates with a server, connects with a controller area network (CAN) of an electric vehicle, and collects data from the CAN and/or other types of data associated with the electric vehicle (e.g., geographical information that identifies a location of an electric vehicle, movement information that identifies whether the electric vehicle is in motion or not, and so on). The systems and methods may perform various actions using some or all of the collected data.
US11027616B2	Vehicle driving device A vehicle driving device including: a rotary electric machine that is a driving force source of a first wheel and a second wheel; a speed reduction device that reduces a speed of a rotation of the rotary electric machine; and a differential gear device that distributes to the first wheel and the second wheel, a driving force that is transmitted from the rotary electric machine via the speed reduction device.
US11027613B2	Regenerative braking control system and method A regenerative braking control system includes at least one sensor adapted to sense a front tire impact event and transmit a sensor signal responsive to the front tire impact event during vehicle braking and a regenerative powertrain interfacing with the at least one sensor and adapted to reduce regenerative braking torque responsive to receiving the sensor signal from the at least one sensor. A regenerative braking control method is also disclosed.
US11027603B1	Latching structure of tonneau cover A truck cover system includes a rail coupled to a wall of the truck, wherein the rail comprises a channel on a top portion of the rail and a latching slot at a side of the rail, wherein the channel extends along a longitudinal direction of the rail and is configured to couple to a cover, and the latching slot extends along the longitudinal direction of the rail; a latching insert inserted in the latching slot, wherein the latching insert comprises a first through hole and a positioning hole; a latching positioner fastened to the latching insert, wherein the latching positioner comprises a second through hole aligned with the first through hole and a positioning pin aligned with the positioning hole; a latching housing releasably latched to the latching positioner.
US11027601B2	Shade roller apparatus A shade roller apparatus is provided to achieve stable attachment of a pull bar to a shading sheet, and reduce the numbers of components and process steps required for the attachment. The pull bar may include a clip portion clipping a front hem of the shading sheet along an entire length of the pull bar, and a bottom wall below the clip portion. While having a front end retained by the clip portion, the shading sheet can wrapped around the pull bar such that the shading sheet sequentially passes over an upper surface and a front surface of the clip portion and then continues along the bottom wall.
US11027599B2	Systems, apparatus, and methods to adjust dimming associated with dual panel sunroofs Systems, apparatus, and methods to adjust dimming associated with dual panel sunroof are disclosed. A disclosed sunroof dimming system for a vehicle includes a first dimmable panel of a sunroof and a second dimmable panel of the sunroof. The first dimmable panel is moveable relative to the second dimmable panel to open or close the sunroof. The sunroof dimming system also includes a controller operatively coupled to the first and second dimmable panels. The controller is configured to adjust dimming associated with the first and second dimmable panels to maintain a brightness of an external light associated with a vehicle cabin that is experienced by a vehicle occupant when the sunroof changes between a closed state and an open state.
US11027588B2	Air conditioning unit for vehicle An air conditioner for a vehicle includes an air conditioning case and a case interior member in the air conditioning case. The case interior member includes a tunnel member and a tunnel exterior guide wall. The tunnel member defines a tunnel channel therein and is arranged in a downstream space defined in an air conditioning case. The tunnel exterior guide wall is configured to guide an air to flow from a warm air passage to an outside of the tunnel channel. A first direction along which the tunnel exterior guide wall extends is closer to a direction, which is opposite to the one direction along which the air flowing from a cool air passage into the downstream space, as compared to a second direction along which the tunnel guide wall extends.
US11027584B1	Flying car with fore and aft lifting surfaces A flying vehicle with folding wings that drives well on the ground and flies well in the air; controlled from inside, it changes from automotive to aircraft configuration without the operator needing to get out of the vehicle. The balance point of the vehicle is located midway between the front and back wheels, providing good handling on the road. In the aircraft configuration with wings unfolded, there is a front wing and a back wing. The incidence of the front wing is controllable, enabling the craft to rotate and take off with a center of gravity located well ahead of the rear wheels. The back wing is fitted with foldable vertical stabilizers near its wing tips. In automobile configuration the wings are folded on top of the body; the wings resemble a roof rack with large surfboards on it. Driven wheels provide motive power on the ground; ducted fans provide thrust for air travel. An autopilot system provides stability and navigation aid, particularly in bad weather or poor visibility. In the roadable configuration, filling water ballast tanks provides additional crosswind stability and crash protection. In its flying configuration, the invention can be licensed as a Light Sport Aircraft.
US11027583B2	Attachment assembly for a vehicle An attachment assembly for a vehicle having a receiver for pulling an object or being pulled. The attachment assembly includes a support member for connection to the receiver and an attachment member connected to the support member to provide both pivotal and rotational movement.
US11027582B2	Method to lock TPMS sensor protocol pressure definition An apparatus and method is provided that includes measuring a tire pressure for at least one tire with at least one tire pressure sensor. The tire pressure sensor has at least a first resolution for transmitting pressure information and a second resolution for transmitting pressure information that is higher than the first resolution. If a measured tire pressure is determined to be above a predetermined pressure threshold, the apparatus and method identify whether the tire pressure sensor has experienced at least one predetermined vehicle operating characteristic, and/or identify whether the tire pressure sensor has been activated by a command. The tire pressure sensor is only locked into the second resolution if the tire pressure sensor has experienced the at least one predetermined vehicle operating characteristic or if the tire pressure sensor has been activated by the command.
US11027577B2	Tire The provided tire has excellent durability regardless of use in a high-humidity environment or contact with water, even though the framework member of the tire is made of a resin material. The resin material is made of a resin composition including 60 mass % or more of a polyamide resin formed by polymerizing an aliphatic diamine having 6 to 20 carbon atoms and an aliphatic dicarboxylic acid having 10 to 20 carbon atoms.
US11027575B2	Bicycle wheel and method of manufacturing bicycle wheel A bicycle wheel includes a first panel member including a first rim portion for mounting a tire, a first hub mounting end connected to a hub, a first spoke portion for connecting the first rim portion and the first hub mounting end, a second panel member having a second rim portion for mounting the tire, a second hub mounting end connected to the hub, and a second spoke portion for connecting the second rim portion and the second hub mounting end, wherein the bicycle wheel is formed by joining the first panel member and the second panel member together such that the first panel member and the second panel member are symmetrical to each other about a line passing through the hub and the rim.
US11027565B2	Card printer alignment bracket The disclosure describes a method for aligning a card on a printer belt. A printer includes the belt, a print unit having a head, and a card feeder having an alignment bracket. The card feeder deposits a card onto the belt along a processing axis in a first orientation. The belt moves the card away from the card feeder in a first direction. The card feeder is positioned in a second orientation where the alignment bracket aligns with the belt. The alignment bracket has a rear wall and a guide extending therefrom that align the card within the alignment bracket. The belt is overdriven in a second direction and the card moves into the alignment bracket for alignment. The belt then moves in the first direction and the card clears the alignment bracket. The card feeder is then positioned in a third orientation to allow printing with the head.
US11027560B2	Printing systems The present disclosure is drawn to printing systems. In one example, a printing system can include a first excimer irradiation source positioned to irradiate a media substrate. Additionally, an inkjet print head can be positioned with respect to the excimer irradiation source to form a printed image on the media substrate after irradiation with the excimer irradiation source.
US11027559B2	Expanding a color gamut of a direct thermal printer A method and apparatus for expanding a color gamut of a direct thermal printer is described. The method includes, in a three-color direct thermal printer having at least a print head, the print head including print head elements, dynamically adjusting a duty cycle of at least one of the colors depending on the color to be printed in each pixel of an image.
US11027555B2	Printing-fluid cartridge including protrusion and interface A printing fluid cartridge a printing fluid cartridge is configured to be inserted into a printing fluid consuming apparatus in an insertion direction. The printing fluid cartridge includes: a storage chamber, a supply portion, a rear surface, an upper surface, an electrical interface, a locking surface, one protrusion, and another protrusion. The storage chamber is configured to store printing fluid. The one protrusion and the another protrusion define a plurality of imaginary planes each of which passes through the one protrusion and the another protrusion. The plurality of imaginary planes includes a specific imaginary plane. The specific imaginary plane is positioned higher than any other imaginary plane between the one protrusion and the another protrusion. The electrical interface is positioned downward relative to the specific imaginary plane in the gravitational direction in the attached posture.
US11027552B2	Printing-fluid cartridge having interfering surface, and set of the printing-fluid cartridges A printing-fluid cartridge is inserted into a prescribed insertion space of a cartridge-attachment section in an insertion direction crossing a gravitational direction to be attached thereto in an attached posture. The printing-fluid cartridge includes: a housing including a storage chamber, a supply portion having a supply hole, an electrical interface disposed at an upper surface of the housing, and an interfering surface. The interfering surface is positioned upward of the storage chamber and extends in a widthwise direction of the housing. The interfering surface is positioned downward and frontward relative to the electrical interface and is configured to abut against a projection provided at another insertion space different from the prescribed insertion space of the cartridge-attachment section during an insertion of the printing-fluid cartridge into the another insertion space.
US11027548B2	Liquid ejection head and method of manufacturing same A liquid ejection head includes an ejection port member that includes an ejection port that ejects a liquid, an energy generating element that generates energy for ejecting the liquid from the ejection port, a terminal electrically connected to the energy generating element, and a substrate portion that supports the ejection port member, the energy generating element, and the terminal. The terminal is connected to a wire member that supplies electric power that drives the energy generating element to the energy generating element, the substrate portion includes a hole portion formed from a surface of the substrate portion on a side opposite to a surface of the substrate portion on which the terminal is provided to a surface where the terminal is exposed, and an area of the surface where the terminal is exposed is smaller than an area of an opening of the hole portion.
US11027547B2	Liquid ejection head A liquid ejection head includes a substrate, an ejection orifice forming member having a plurality of ejection orifices for ejecting a liquid, and an intermediate layer provided between the substrate and the ejection orifice forming member. The substrate has a supply path for supplying the liquid to the plurality of ejection orifices, the ejection orifice forming member has a common liquid chamber communicating with the plurality of ejection orifices, the supply path and the common liquid chamber communicate with each other via a filter portion including a plurality of holes formed in the intermediate layer, the ejection orifice forming member has a wall portion that protrudes into the common liquid chamber at a position opposed to the filter portion, and the wall portion extends along a direction intersecting an arrangement direction of the plurality of ejection orifices.
US11027543B2	Printing apparatus and method of determining minimum discharge energy A printing apparatus measures a temperature of an electrothermal transducer by a corresponding temperature detection element, detects, based on the measured temperature, a peak voltage which indicates a point of change, from a state where ink is discharged normally from a printhead to a state where the ink is not discharged from the printhead, and compares the peak voltage with a threshold value. The measurement, detection, and comparison are repeated until the peal voltage becomes equal to or more than the threshold value. Energy supplied to the electrothermal transducer at a time in which the peak voltage is determined to be equal to or more than the threshold is determined to be minimum discharge energy.
US11027540B2	Inkjet recording device An object of the present invention is to provide an inkjet recording device capable of adjusting a clearance between prints formed by two nozzles (114, 115), and capable of printing a print content at a high speed. In order to achieve the object, there is provided an inkjet recording device which has two sub-print heads including nozzles (114, 115), charging electrodes (116, 117), deflection electrodes (118, 119), and gutters (120, 121), in which the two nozzles are disposed in a deflection direction of ink particles, and which performs printing on a printed object (124) while moving the printed object (124) relative to the ink particles in a direction substantially perpendicular to the deflection direction of the ink particles, the inkjet recording device having a function for reducing a clearance between print results (125, 126), printed by the two nozzles (114, 115), by controlling a voltage applied to the charging electrodes (116, 117) and a voltage applied to the deflection electrode (118, 119).
US11027537B2	Measured sensor distance correction Example implementations relate to determining a correction factor that converts a measured sensor distance to a calibrated sensor distance. The measured sensor distance may be based on an amount of substrate advancement through a web printing press between detecting a mark on the substrate at a first sensor and detecting the mark at a second sensor. The calibrated sensor distance may be the separation between the first sensor and the second sensor.
US11027534B2	Fiber composite material and manufacturing method thereof A fiber composite material and a manufacturing method thereof are provided. The fiber composite material includes: a fiber prepreg layer including a first resin and fibers impregnated with the first resin; and a plurality of strip-shaped composite resin layers including multi-layered carbon nanotubes and a second resin disposed on the fiber prepreg layer, wherein the plurality of the strip-shaped composite resin layers and the fiber prepreg layer together form a hollow tubular body, and a length direction of the plurality of strip-shaped composite resin layer is at an angle of from 0 degree and less than 90 degrees with respect to an extending direction of the fiber prepreg layer.
US11027528B2	Laminated vehicle windshield with internal luminous sign(s) A laminated vehicle windshield containing internal luminous information, includes a first glazing, a lamination interlayer, a second glazing and peripheral exterior and interior masking layers. A first curved organic-light-emitting-diode (OLED) device is between the second and third main faces windshield, the first OLED device forming a first sign.
US11027523B2	Polyester film incorporating silicone for release of canned meat products Embodiments herein relates to a Bisphenol A-free multi-layer biaxially oriented polyester (BOPET) film, for lamination on metal sheets, which could be used for food containers. The BOPET film has at least one outer release layer, which aids in the release of food, such as a high protein food source, when food is cooked and sterilized in direct contact with the outer release layer. The BOPET film can be laminated to metals used in the manufacture of food containers with the outer release layer being exposed to allow a direct food contact between the surface of the outer release layer and food. More particularly, the invention relates to a novel outer release layer resin composition comprising an ultra high molecular weight siloxane polymer and a polyethylene trephthalate resin; and an alkali-metal phosphate and a phosphoric acid compound added, during polymerization of the outer release layer resin composition, as a catalyst/additive package to the ingredients forming the outer release layer resin composition. A wax component can be added in the outer release layer, for more robust release performance.
US11027521B2	Splice joint in laminate composite structure Layers of plies of composite material are laid on a convex tool surface. A first layer is placed with a first ply of a first section having a gap edge adjacent a gap edge of a first ply of a second section, the edges being parallel and a contraction distance from each other. A second layer is placed with a second ply of the first section having a gap edge adjacent a gap edge of a second ply of the second section, the edges being parallel and a contraction distance from each other, the second ply of the second section overlapping onto the first ply of the first section by a splice distance. Consolidation and curing cause contraction of the layers toward the tool, allowing the adjacent gap edges of each layer to be in close proximity or in contact after moving toward each other during the contraction.
US11027519B2	Self-stressing engineered composite materials, methods of self-stressing engineered composite materials, and self-stressing reinforcement for same Self-stressing engineered composites that include a matrix containing self-stressing reinforcement that is activated by an activator that causes, in situ, the self-stressing reinforcement to transfer at least some of its pre-stress into portions of the matrix adjacent the self-stressing reinforcement. In some embodiments, the activator can be of a self-activating, an internal activating, and/or an external activating type. In some embodiments, the self-stressing reinforcement includes an active component that holds and transfers pre-stress to a matrix and a releasing component that causes the active component to transfer its pre-stress to the matrix. In some embodiments, the self-stressing reinforcement is initially unstressed and becomes stressed upon activation. Various engineered composites, self-stressing reinforcement, and applications of self-stressing engineered composites are disclosed.
US11027518B2	Electrically conductive multi-layer material The invention relates to conductive multi-layer materials for leak detection applications. The electrically conductive multi-layer material comprises a woven glass fibre web (2) having a binding agent (4) and a fire retardant compound (5), which is impregnated with electrically conductive carbon particles (6), wherein one side of the glass fibre web (2) is coated with metallic electrically conductive layer (10) by the means of vacuum deposition.
US11027517B2	Decorative laminates including thermoplastic ink layers and related methods Decorative laminates including thermoplastic ink layers and related methods are disclosed. An example apparatus includes a reinforcing layer to provide a rigidity to a decorative laminate, thermoplastic ink applied to the reinforcing layer to form a decorative pattern of the decorative laminate, and a film layer coupled to the thermoplastic ink to form the decorative laminate. The film layer is to preserve the decorative pattern. The thermoplastic ink is solidified when the film layer is coupled to the thermoplastic ink.
US11027516B2	Body wiping sheet A body wiping sheet (1) comprising two surface layers (2, 3) each comprising a non-woven fabric, and a water-absorbent polymer layer that contains a water-absorbent polymer and that is disposed between the two surface layers (2, 3) in a stacked manner.
US11027515B2	System and method for producing multi-layered board having at least three mediums with at least two mediums being different A system and method for producing a board product characterized by having two corrugated mediums and at least one embossed medium in the board product. The board product may further include one or more facings that are adhesively coupled to either the corrugated medium, the embossed medium, or both. Generally speaking, a corrugated medium may be characterized as a paper product that exhibits flutes induced by a cross-corrugating process such that the induced flutes are perpendicular (or at least not congruent) with the machine direction of the paper product. An embossed medium may be characterized as a paper product that exhibits flutes induced by a linear-embossing process such that the induced flutes are aligned with the machine direction of the paper product. A resultant board product is stronger and more efficiently produced because of the linearly-embossed medium harnessing the natural strength of the paper in the machine direction.
US11027509B2	Mould for a tire tread comprising concealed channels Mould for moulding a tread of a tire, this tread having a thickness of material to be worn away and a tread surface intended to come into contact with the road surface when the tire is running, this mould having a moulding surface intended to mould the tread surface of the tread, and having a moulding element formed of a blade and a bar, the blade being attached to the moulding surface to mould a sipe in the tread, the bar, borne by the blade to form an enlarged part of maximum width D, being intended to mould a channel in the tread, this channel itself being intended to form a new groove when the tread becomes part worn. Each blade is delimited by two lateral faces forming between them a mean angle of between 6° degrees and 18°. The blade width decreasing from the mould surface when new, as far as the connection with the bar, the blade width meets the bar being at least equal to between 0.2 and 0.4 times the maximum width D.
US11027508B2	Method for retreading a tire casing using a roller A method of retreading a tire casing includes the step of disposing a cured rubber tread on a carcass with a layer of hot-melt material interposed between the tread and the carcass. The method continues with the step of rollering the tread by means of at least one roller with a width (r) that is less than a width (b) of the tread.
US11027505B2	Method for checking formation of beads of tyres Method for checking the formation of beads of tyres including: arranging a carcass sleeve with formed beads with the carcass sleeve in rotation, acquiring at least an image of a circumferential portion of external surface including the respective edges of the end flaps turned up; processing the image in order to determine a circumferential trend of the axial distance of each edge from an axial reference plane; and detecting possible defects of the beads as a function of such trend.
US11027500B1	Construction of structures by joining of pre-formed tape Various components, such as radio frequency (RF) or thermal reflectors, may be constructed from joining of pre-formed tape. For reflectors, this process may reduce the number of ribs, only require partial ribs, or eliminate the use of ribs altogether. To build such a reflector, a spool of tape, a joining tractor, and a foundation ring may be employed.
US11027498B2	Ultrasonic welding of dissimilar sheet materials A ultrasonic welding method of joining dissimilar-material workpieces, such as sheet materials, and the joined components formed thereby. The method includes applying ultrasonic energy to a thermoplastic piece to fill a hole of a dissimilar piece to form a weld point that is made up with polymer from the thermoplastic piece. In general, the geometry of the thermoplastic piece is not altered during the process. The dissimilar piece generally has a higher melting temperate and can be metal, thermoset polymers, or other thermoplastic material. The welded pieces can be arranged in a lap, laminate, or double lap configuration. In some embodiments, the hole of the dissimilar sheet material includes undercut features that improve the mechanical interlock between the dissimilar pieces. In some embodiments, the weld point has a mushroom cap to improve mechanical interlock.
US11027496B2	Adhesive bonding and sealing of seams and joints The adhesive bonding and sealing by application of adhesive material and sealing material at corresponding seams and joints, wherein the adhesive material is arranged to rest directly, at least in part, on the sealing material.
US11027491B2	Powder recirculating additive manufacturing apparatus and method A method of making a part by an additive manufacturing process includes the steps of: (a) supporting a build platform on a support surface; (b) traversing a powder dispenser positioned above the support surface across the build platform, while dispensing powder from the powder dispenser, so as to deposit the powder over the build platform; (c) traversing the build platform with a scraper to scrape the deposited powder, so as to form a layer increment of powder; (d) using a directed energy source to fuse the layer increment of powder in a pattern corresponding to a cross-sectional layer of the part; and (e) repeating in a cycle steps (b) through (d) to build up the part in a layer-by-layer fashion.
US11027483B2	Valve incorporating temporary phase change material Described herein are various embodiments of a valve that may be opened and closed using a thixotropic or “stress yield” material, or other material that temporarily changes phase upon application of energy to the material. More particularly, some embodiments may include a valve that is opened and closed using a granular gel that is a temporary phase change material.
US11027480B2	Method for manufacturing high-pressure tank A method for manufacturing a high pressure tank capable of uniformly heating a thermosetting resin in a short time is provided. A method for manufacturing a high-pressure tank including: a step (a) of preparing a tank intermediate product including a fiber-reinforced resin layer formed by winding a carbon fiber impregnated with a thermosetting resin around a liner including a cap attached thereto; and a step (b) of performing a process for thermosetting the fiber-reinforced resin layer of the tank intermediate product by induction-heating the fiber-reinforced resin layer using induction-heating means, in which: the induction-heating means includes first induction-heating means for induction-heating a trunk part of the tank intermediate product and second induction-heating means for induction-heating a dome part of the tank intermediate product; and a temperature of the trunk part of the tank intermediate product and a temperature of the dome part thereof are controlled independently.
US11027479B2	Thermal control mold for making three-dimensional microstructures Methods for fabricating three-dimensional microstructures are provided. The method includes disposing a reflow material on a mold, heating the reflow material, and creating a pressure gradient across the reflow material to reflow the material towards a bottom surface of the mold. The mold includes a molding region, a boundary region, and a thermal-isolating region disposed therebetween. The molding region includes a cavity and a projection projecting upwards from a bottom surface of the cavity. The thermal-isolating region includes at least one pocket formed adjacent to and along a perimeter of the cavity of the molding region. During heating, the temperature of the molding region is higher than that of the boundary region and the thermal-isolating region controls the thermal conductivity and mass therebetween. The material reflows towards the bottom surface of the cavity and the protrusion helps shapes the reflow material to form a substantially symmetrical three-dimensional microstructure.
US11027478B2	Thermoform packaging machine and method of forming-in a film web into cardboard elements A thermoform packaging machine comprising a forming station. The forming station comprises at least one forming tool lower part, the forming tool lower part may be movable transversely to an operating direction of the thermoform packaging machine. The forming tool lower part may comprise at least one reception unit with one or a plurality of troughs for receiving cardboard elements. At a forming position the forming tool lower parts are in contact with the forming tool upper parts such that the first film web may be formed-in into the forming tool lower parts. Further, the first film web may be formed-in into the cardboard elements during the forming process and, in the case of a skin film, an adhering or an adhesive connection may be established between the skin film and the inner surfaces of the cardboard elements.
US11027475B2	Screw-type extruder A screw extruder which extrudes a kneaded material includes a screw having a helical flight provided on an outer peripheral surface of a shaft portion thereof, and a chamber housing the screw. In the screw extruder, a flight thickening portion is provided at a part which is a tip portion of the flight and is on the reverse side of a rotation direction of the flight.
US11027474B2	Fluidic systems, devices and methods for inducing anisotropy in polymeric materials Systems, devices and methods are provided for fabricating anisotropic polymer materials. According to various embodiments, a fluidic device is employed to distribute a polymer solution and a flow-confining solution in order to generate a layered flow, where the layered flow is formed such that a polymer liquid sheet is sheathed on opposing sides by flow-confining liquid sheets. The fluidic device includes first and second fluid conduits, where the first fluid conduit receives the layered flow. The second fluid conduit has a reduced height relative to the first fluid conduit, such that the layered flow is constricted as it flows through the second fluid conduit. The constriction formed by the second flow conduit causes hydrodynamic focusing, reducing the thickness of the polymer liquid sheet, and inducing molecular alignment and anisotropy within the polymer liquid sheet as it is hardened and as strain is applied during extrusion of the sheet.
US11027470B1	Molding system for preparing injuection-molded article A molding system includes a molding machine having a screw, a driving motor driving the screw to move a molding resin; a mold disposed on the molding machine and connected to the barrel of the molding machine to receive the molding resin, and having a mold cavity with a die swell structure for being filled with the molding resin; a processing module simulating a filling process of the molding resin from the barrel into the molding cavity based on a molding condition including a predetermined screw speed for the molding machine; and a controller operably communicating with the molding machine to control the driving motor of the molding machine based on the molding conditions to move the screw at the predetermined screw speed to transfer the molding resin at a corresponding flow rate to perform an actual molding process for preparing the injection-molded article.
US11027469B2	Mold system including separable, variable mold portions for forming casting article for investment casting A mold system and method for forming a casting article for investment casting is disclosed. The mold system includes a mold for receiving therein a selected core chosen from a plurality of varied cores. The mold includes a plurality of separable mold portions that are coupleable together to create the mold and configured to form a sacrificial material from a sacrificial material fluid about the selected core. At least one selected separable mold portion of the plurality of separable mold portions includes a set of varied interchangeable versions of the at least one selected separable mold portion. Each varied interchangeable version of the selected separable mold portion is configured to accommodate a different core of the plurality of varied cores. A number of systems for controlling a temperature of the mold are also disclosed.
US11027466B2	Process for producing foam molded parts with aesthetic surfaces by foam injection molding The invention relates to a process for producing a foam molded part, wherein a foamable material S comprising a thermoplastic polymer matrix M and at least one foaming agent F is foamed by foam injection molding. The polymer matrix M is preferably based on at least one thermoplastic styrene copolymer, such as ABS and ASA, and wherein the at least one foaming agent F is selected from chemical foaming agents, releasing carbon dioxide, and physical foaming agents, being carbon dioxide or nitrogen.
US11027464B2	Headrest and method of manufacturing the headrest A method of manufacturing a headrest including a stay, a skin material, a cushion material, and a dynamic damper is provided. The method includes arranging the skin material in a molding die, arranging the stay, to which an air bag is attached in such a manner as to cover the dynamic damper, inside the skin material, and injecting a foamable synthetic resin raw material into the skin material to foam-mold the injected foamable synthetic resin raw material integrally with the stay.
US11027455B2	Formliner for forming a pattern in curable material and method of use Features for formliners to form a decorative pattern in a curable material and methods of using the same are disclosed. An improved formliner is disclosed with substantially seamlessly connecting components that reduces the need for using adhesives for interconnecting a plurality of formliners in a pattern. Further, the formliner is configured to reduce and/or substantially eliminate visible seams in order to create a more natural appearance in a finished product of the curable material.
US11027450B2	Cutting heads, cutting machines equipped therewith, and methods of operation Cutting heads and machines equipped therewith. The cutting heads include axially-spaced annular-shaped structural members and circumferentially-spaced support segments between the structural members. Each support segment has a leading edge and a trailing edge, a knife support surface defined on an inner surface region adjacent the leading edge of the support segment, and a gate located adjacent the trailing edge of the support segment. A knife assembly is located adjacent the leading edge of each support segment. Each knife assembly includes a holder opposing one of the knife support surfaces of the support segments and adapted to clamp a knife between the holder and knife support surface. The cutting head may further have camming units that secure the support segments between the structural members, camming units that clamp the knives to the knife support surfaces, and/or adjustment pins that deflect the gates of the support segments.
US11027448B2	Apparatus and method for converting a sheet into a continuous strip Disclosed is an apparatus and a method for converting a sheet into a continuous strip, wherein the sheet has a sequence of cuts extending in a cutting direction transversely across the sheet with respect to the longitudinal direction to form a plurality of interconnected sheet sections, wherein the continuous strip has zig-zag sections, wherein the sheet sections are arranged to be pulled apart in a feeding direction to form the zig-zag sections, wherein the apparatus includes a separator device with a retaining device for retaining an upstream sheet section with respect to a consecutive downstream sheet section in the feeding direction and a sensor device for detecting the pulling apart of the downstream sheet section from the upstream sheet section.
US11027447B2	Apparatus and related methods for trimming dried cannabis flowers In a preferred embodiment, the apparatus comprises: (1) a box with specifically designed blades for cutting; (2) a motor for rotating the blades over each other; (3) a sweeper mechanism to gently move the flowers around the enclosure blade; and, (4) a brush mechanism to gently tumble flowers over the blade surface.
US11027446B2	Pizza pan with precise cutting guidelines A cooking pan includes guidelines configured to aid in precisely cutting a food product into slices with desired shapes. The cooking pan includes a flat base, at least one raised wall surrounding the flat base, and a rim at a top of the raised wall. The pan further includes a plurality of the guidelines formed upon the pan, each guideline comprising a depressed groove, wherein each guideline extends contiguously from the flat base, up the raised wall, and onto the rim.
US11027443B2	Shaving razor cartridge and method of manufacture A shaving razor cartridge with a housing molded from a first polymeric material and having a top surface and an opposing bottom surface. The housing has a wall partially defining an opening extending from the top surface to the bottom surface. The wall has a pair of arms each with a distal end extending toward each other defining a gap. A guard is toward a front of the housing. A cap is toward a rear of the housing. At least one blade is mounted between the guard and the cap. A bridge interconnects the distal ends. The bridge is molded from a second polymeric material that is different than the first polymeric material.
US11027437B2	Apparatus, system and method for providing a conformable vacuum cup for an end effector An apparatus, system and method for providing a vacuum grip for an end effector. The apparatus, system and method may include a vacuum draw eyelet connectively associated with a vacuum at a base portion thereof, and having a larger cross-sectional circumference at a topmost portion thereof than at the base portion; an extending cup foam portion including a receiving portion suitable for receiving therewithin the larger cross-sectional circumference of the topmost portion; and a wire clip having two legs inserted along a cross-sectional plane of the extending cup foam portion, the two legs being suitable to compress the receiving portion into frictional contact at two tangent points on a second cross-sectional circumference of the vacuum draw eyelet below the larger cross-sectional circumference.
US11027434B2	Telepresence controller and system using magnetorheological fluid clutch apparatuses A telepresence controller is provided for interaction with a remote telepresence session to control haptic interactions between an end effector and the remote telepresence session. Force sensor(s) monitor force(s) applied to an end effector. Position sensor(s) monitor a position of the end effector. The telepresence controller communicates with the remote telepresence session to exchange position data and force data indicative of concurrent haptic movements of the end effector and an object in the remote telepresence session. Magnetorheological fluid clutch apparatus(es) have an input adapted to be connected to a power source and configured to receive a degree of actuation (DOA) therefrom, the magnetorheological fluid clutch apparatus(es) having an output being actuatable to selectively transmit the received DOA to the end effector by controlled slippage. A force controller module determines a force input required on the end effector as a function of haptic events for the object in the remote telepresence session. A clutch driver module drives the magnetorheological fluid clutch apparatus with the controlled slippage being as a function of the force input.
US11027433B2	Robot system and control method of robot system for taking out workpieces loaded in bulk A controller includes a generation unit that generates three-dimensional information, a deletion unit that deletes information about at least part of the measurement points in the three-dimensional information, and a determination unit that determines a state where the robot grips a workpiece. The generation unit generates first three-dimensional information before the robot implements an operation of gripping a target workpiece. The generation unit generates second three-dimensional information after the robot has implemented an operation of lifting the target workpiece. The deletion unit generates third three-dimensional information in which information about measurement points in the second three-dimensional information is deleted from the first three-dimensional information. The determination unit determines whether or not the workpiece in the third three-dimensional information matches the target workpiece.
US11027430B2	Systems and methods for latency compensation in robotic teleoperation A method includes presenting a virtual representation of an environment of a robot, receiving a first user command to control the robot within the environment, rendering a predicted version of the virtual representation during a period of latency in which current data pertaining to the environment of the robot is not available, updating the predicted version of the virtual representation based upon a second user command received during the period of latency, and upon conclusion of the period of latency, reconciling the predicted version of the virtual representation with current data pertaining to the environment of the robot.
US11027429B2	Robot A robot with a noncontact sensor is configured to: perform the predetermined motion in a state where the moving object does not enter, and thereby store, for each of a plurality of measurement points set in a movable range of the robot, an output value of the noncontact sensor as a reference output value in advance, and stop the predetermined motion when the output value of the noncontact sensor changes from the reference output value at the measurement point closest to a current operating position of the robot by a first threshold value or larger when the robot is performing the predetermined motion in a state where the moving object could possibly enter and the current operating position of the robot is in a range in which it is necessary to determine an entering state of the moving object.
US11027422B2	Rotary actuator and robot Provided, for example, is a rotary actuator that is equipped with a rotation restricting mechanism for restricting the rotation of a stopped rotor. The rotation restricting mechanism is provided with: a rotation-side restricting member fixed to the rotor; a fixed-side restricting member that engages with the rotation-side restricting member and restricts the movement of the rotation-side restricting member in the circumferential direction of the rotor; and a drive mechanism that moves the fixed-side restricting member in the axial direction of the rotor. A plurality of protrusions that project toward the outer side of the radial direction of the rotor are formed in the rotation-side restricting member. A restricting part 46a that penetrates in between the protrusions in the circumferential direction and restricts the movement of the rotation-side restricting member in the circumferential direction is formed in the fixed-side restricting member.
US11027420B2	Modular cargo storage apparatus for use on a base platform of a modular autonomous bot apparatus that transports an item being shipped A modular cargo storage system (CSS) is described for use on a base platform of a modular autonomous bot apparatus that transports an item being shipped. The modular CSS includes a set of folding structural walls, an interlocking alignment interface on at least one of the walls, and a modular component power and data transport bus. The walls at least partially enclose a payload area above the base platform. The interlocking alignment interface has a set of latches and a locking handle coupled to the set of latches that actuates the latches to interlock with the base platform. The power and data transport bus have top and bottom side modular component electronics interfaces where each interface has a power conduit outlet and a command and data communication interface.
US11027418B2	Robot and working method by the robot A robot and a working method by the robot is capable of favorably carrying out a specific work without requiring a jig for fixing an object, such as a workpiece etc., a device for adjusting the posture of the object, etc. One example of the robot includes a first robotic arm having at a tip end a hand part according to a specific work to be performed to an object, and a second robotic arm having at a tip end a hand part according to an assisting work to assist the specific work. The first robotic arm is configured to perform the specific work to the object. The second robotic arm is configured to perform the assisting work to regulate a movement of the object in a given direction, when the first robotic arm performs the specific work.
US11027416B2	Two-wheeled self-balancing robot The present disclosure discloses a two-wheeled self-balancing robot which solves the technical problems in the prior art that the robot can only travel on a flat ground and its driving environments are limited by making improvements in its mechanical structure. The two-wheeled self-balancing robot comprises a vehicle body with wheels mounted on both sides thereof. The vehicle body comprises a parallelogram frame which can deform tiltedly. The vehicle body is provided with a stage, and the stage is hinged with the parallelogram frame. The parallelogram frame is provided with a first motor. The first motor drives the parallelogram frame to deform tiltedly according to road conditions so as to always keep the stage horizontal. The two-wheeled self-balancing robot according to the present disclosure can adapt to complicated road conditions, and its stage always keeps horizontal such that the object carried is not prone to fall off.
US11027415B1	Generalized coordinate surrogates for integrated estimation and control A robotic device includes a control system. The control system receives a first measurement indicative of a first distance between a center of mass of the machine and a first position in which a first leg of the machine last made initial contact with a surface. The control system also receives a second measurement indicative of a second distance between the center of mass of the machine and a second position in which the first leg of the machine was last raised from the surface. The control system further determines a third position in which to place a second leg of the machine based on the received first measurement and the received second measurement. Additionally, the control system provides instructions to move the second leg of the machine to the determined third position.
US11027408B2	Powered tool device A powered tool device may include a first handle grip coupled to a first handle bar and a second handle grip coupled to a second handle bar. A first battery may be coupled to the first handle bar, and a second battery may be coupled to the second handle bar. The two handle bars, handle grips, and their respective batteries may be separated from each other via a separation structure that may separate the two handle bars by a distance which may allow portions of the body of a user to be between the handle bars. Optionally, the separation structure may be moved between an extended position and a compacted position.
US11027404B2	Lubricant-impregnated bushing for impact tool A power tool includes a housing having a motor housing portion and a front casing coupled to the motor housing portion. The power tool also includes an electric motor positioned within the motor housing portion, a drive assembly having an output shaft to which a tool element for performing work on a workpiece is attachable, and a powdered metal bushing disposed within the front casing that rotatably supports the output shaft.
US11027399B2	Hand tool such as a wire stripper or combination pliers A hand tool and a wire stripper. The hand tool may include a first jaw portion and a second jaw portion having a spring constant more than about 2,225 lbs./in., measured when a force is applied in a direction parallel to the pivot axis to an associated jaw tip with a pivot member being held. The hand tool may include a jaw portion having a gripping surface and an angled wall connected to a side wall and defining a wire stripping portion, the wire stripping portion including a cutting edge and a recess defined in the angled wall, the recess extending from the cutting edge to an end at the one of the side walls, the angled wall being arranged non-parallel to the gripping surface and non-perpendicular to the side wall. The wire stripper may be a forged wire stripper including jaws defining a stripping aperture for Romex® NM wire.
US11027396B2	System for blast-cleaning a barge bottom A system for blast-cleaning a barge bottom providing for safety and avoidance of damage to the barge and to persons, where a barge is blast-cleaned with a blasting tractor having a transverse track beam along which positioning units move blaster heads. In one embodiment, the blasting tractor is controlled by a person in a cab of the blasting tractor, where the operator can see the blaster heads. In another embodiment, the blasting tractor is robotically controlled from a robotic controller which has access to a three-dimensional plan of the barge, communicating with the robotic blasting tractor via RF antennae, and receiving real-time data from sensors located on each blaster head. Optionally, the system for blast-cleaning a barge can provide blaster-head cameras for real-time remote monitoring of operations and for recording of the operations allowing review of any issue, such as damage, that might arise.
US11027393B2	Adjustable sander pad assembly An adjustable sander pad assembly comprising a backer flange, multiple support fingers, multiple adjustment supports, a sander plate, and an adjustment ring; wherein the multiple support fingers each has a first and a second attachment point, wherein the first attachment point is attached to the adjustment support, wherein the second attachment point is attached to the adjustment ring, wherein the support fingers, the adjustment supports, the sander plate, and the adjustment ring are mounted on the backer flange, and wherein the adjustment ring is rotated to move the support fingers and adjustment supports radially from a retracted position to an extended position.
US11027392B1	Compact multi-material cut-off tool A compact multi-material cut-off tool includes a housing, and an arbor rotatably supported by the housing upon which a cutting disk is attachable for co-rotation therewith. A motor is coupled to the arbor to provide torque thereto. A controller is operable to selectively drive the motor in a first rotational direction and an opposite, second rotational direction. A first lighting element is coupled to a first portion of the housing, and a second lighting element is coupled to a second portion of the housing. One of the first lighting element and the second lighting element is configured to be activated by the controller in response to the motor being driven in the first rotational direction. The other of the first lighting element and the second lighting element is configured to be activated by the controller in response to the motor being driven in the second rotational direction.
US11027388B2	Machining system with interlock circuit A machining system comprises a machining device that machines a workpiece, a set-up station with which pallet workpiece attachment/detachment is carried out, and a pallet conveyance device that conveys the pallet between the machining device and the set-up station. A partially cylindrical operator door, which can rotate around a set-up table on which the pallet is mounted, includes a partially cylindrical outer door and a partially cylindrical inner door which rotate following coaxial circular trajectories of different radii. The set-up station is provided with an interlocking mechanism that causes the outer door and the inner door to rotate in an interlocked manner so that a shielded state is constantly maintained between the operator side and the pallet conveyance device side.
US11027384B2	Fast tool changing method with pre-unclamping process A fast tool changing method with pre-unclamping step for controlling operations of the spindle, tool unclamping cylinder, and tool changing arm. The spindle has one end clamping the tool at the clamping position. The method includes following steps. In a tool pre-unclamping step, the clamp end of the spindle moves the used tool to a pre-unclamping position; the tool unclamping cylinder pushes the used tool to leave a taper of the spindle. In a tool changing step, the tool changing arm rotates to clamp the used tool and pulls the used tool away from the clamp end, and further aligns a target tool with the clamp end. In a tool inserting step, the tool changing arm inserts the target tool into the clamp end, to be clamped therein. Therefore, the tool unclamping and tool clamping operations are accelerated.
US11027383B2	Workpiece clamping device, and processing system having workpiece clamping device A workpiece clamping device able to perform a set-up changing operation for clamping members depending on the kind of a workpiece to be processed, at a low cost, by a simple method. The workpiece clamping device includes a bracket, a movable part which is movable with respect to the bracket, a clamping member to be attached to and detached from the bracket or the movable part, to clamp a workpiece, and a detachable device for detachably coupling the bracket or the movable part to the clamping member.
US11027377B2	Ring installation device A ring installation device for installing a ring to a part includes an inner mandrel which is tapered in order to expand the ring. An outer mandrel is tubular such that the inner mandrel is received within the outer mandrel and such that the inner mandrel is moveable within the outer mandrel along an axis. A ring stripper is tubular such that the outer mandrel is receive within the ring stripper and such that the outer mandrel is moveable within the inner mandrel along the axis. The inner mandrel is moveable along the axis relative to the outer mandrel and the ring stripper from an inner mandrel first position to an inner mandrel second position. The outer mandrel is moveable by the inner mandrel along the axis relative to the ring stripper from an outer mandrel first position to an outer mandrel second position.
US11027375B2	Automatic and manual welding apparatus An automatic and manual welding apparatus includes an operation changeover switch which is provided to be capable of switching a manual input mode for switching off power supplied to an infeed motor to and from an automatic input mode for applying power supplied to the infeed motor, so as to switch the rotation of the infeed motor automatically and manually. A control unit controls the infeed motor such that the power supplied to the forward and backward transfer motor is switched off when the input of the operation changeover switch is in a manual input mode and the power to the infeed motor is applied when the input of the operation changeover switch is in an automatic input mode.
US11027374B2	Particles, connecting material and connection structure Particles that can suppress the occurrence of cracking during a stress load in a connection part that connects two members to be connected are provided. The particles according to the present invention are particles used to obtain a connecting material for forming the connection part that connects two members to be connected, and the particles are used for forming the connection part such that thickness of the connection part after connection exceeds twice the average particle diameter of the particles before connection, or the particles have an average particle diameter of 0.1 μm or more and 15 μm or less, the particles have a 10% K value of exceeding 3000 N/mm2 and 20000 K/mm2 or less, and the particles have a particle diameter CV value of 50% or less.
US11027369B2	Laser peening processing device and laser peening processing method According to one implementation, a laser peening processing device includes a laser peening processing device includes a laser oscillator, a nozzle and an inclining structure. The laser oscillator emits laser light. The nozzle condenses and irradiates the laser light toward a surface to be processed of a workpiece, with injecting liquid toward the surface to be processed. The inclining structure inclines at least one of the nozzle and the workpiece to make an injection direction of the liquid be different from a normal direction of the surface to be processed. The air bubbles arising by at least one of collision between the liquid and the surface to be processed and shock by irradiation of the laser light on the surface to be processed are flowed in a direction depending on an inclined direction of the surface to the injection direction of the liquid.
US11027367B2	Tool for laser beam processing, laser beam processing apparatus and method for laser beam processing A tool for laser beam processing is provided. The tool includes an upper tool and a lower tool, which are able to be advanced toward one another by way of a press, such that at least one component is able to be fixed in a predefined position between the upper tool and the lower tool. At least one laser beam exit surface, which is part of an inner surface of the upper tool or lower tool, and at least one laser beam guide, into which laser radiation is able to be coupled and is able to be directed through the laser beam exit surface onto a processing location on the component are provided. A control device, which enables and/or disables the coupling of laser radiation into the at least one laser beam guide depending on the advancing movement between upper tool and lower tool is provided. Furthermore, a laser beam processing apparatus and a method for laser beam processing are also provided.
US11027365B2	Laser beam diverting aperture and reflection capture device A laser beam trimming and redirecting device having an aperture therein, the aperture defined by a inner beveled surface for focusing the laser beam directed therethrough and the aperture having an outer beveled surface, or beveled edge, for trimming the laser beam and reflecting the excess energy back towards a source at an angle other than 180 degrees. A reflection capture device positionable upstream of the trimming and redirecting device is configured to absorb the reflected energy instead of the laser beam source or delivery components. The capture device is a liquid cooled device so as dissipate the heat energy absorbed preventing degradation of the device.
US11027358B2	Systems and methods for auto-tuning a GMAW welding process Systems and methods for auto-tuning a MIG welding process are disclosed. A welding-type power supply may include a power conversion circuitry configured to convert input power to welding-type power; and a controller configured to control the power conversion circuitry based on a plurality of operating parameters. The operating parameters may include an inductance parameter, a slope parameter, or a wet time parameter. During the welding process, in order to control the power conversion circuitry, the system may measure an output from the power conversion circuitry, and may update the inductance parameter, the slope parameter, or the wet time parameter.
US11027357B2	Methods and apparatus to provide welding power Methods and apparatus to provide welding power are disclosed. An example welding-type power supply includes: a transformer having first and second secondary windings; switching elements configured to control current flow from the first and second secondary windings to an output; and a control circuit configured to control the switching elements to selectively output a positive output voltage or a negative output voltage without a separate rectifier stage by selecting, based on an output voltage polarity, a first subset of the switching elements to perform rectification.
US11027356B2	Welder generator engine speed control An engine-driven welder generator is controlled based upon power draw for welding and other applications. Once a welding arc is initiated, the power draw is monitored. The engine speed, and therefore the power output of the generator, may be increased or maintained based upon the power draw. The power draw may include both welding power draw and auxiliary power draw. The engine speed is increased in increments. The initial engine speed and subsequent increments may depend upon particular welding processes or regimes.
US11027345B2	Miter saw and workpiece support therefor A miter saw and a workpiece support are provided. The workpiece support has a circular disc-shaped turntable penetrated by a saw blade slot serving as a passage for the saw blade lowered into the working position, a holder on one side for fastening the saw unit, and a radial arm which extends the turntable and the saw blade slot in the longitudinal direction of the slot radially outwards on a side opposite the holder. A radial arm connection is provided, on which the radial arm is detachably and co-rotatably attached to the turntable, or on which a radially outer radial arm outer portion of the radial arm is detachably and co-rotatably attached to a radially inner radial arm inner portion of the radial arm formed integrally with the turntable. The miter saw has blade that can be moved transversely and lowered from a position above the workpiece support.
US11027339B2	Cutting insert, cutting tool, and method of manufacturing machined product A cutting insert based on a non-limiting aspect has a first member and a second member joined to the first member. The second member has an upper surface and a side surface adjacent to the upper surface. The upper surface includes a first side, a second side and a corner. The upper surface has a first convex portion extending toward the corner, and a second convex portion extending from the first convex portion toward the first side. The second convex portion has a first end portion and a second end portion located closer to the corner than the first end portion. A first length from the first end to the first side is less than a second length from the second end portion to the first side in a top view.
US11027336B2	Splatter shield systems and methods for additive manufacturing A splatter shield system for an additive manufacturing machine includes one or more splatter shields configured to cover at least a portion of a build area during energy application such that the at least one splatter shield is positioned between an energy source of an additive manufacturing machine and the build area during energy application. The one or more splatter shields are transparent to an energy source (e.g., a laser) of the additive manufacturing system such that energy application occurs through the splatter shield.
US11027334B2	Micro-nano composite powder dedicated for laser repair of tiny cracks in stainless steel surface A micro-nano composite powder dedicated for laser repair of tiny crack on stainless steel surface, includes 3 wt %-7 wt % of nano-WC, 0.5 wt %-2 wt % of nano-Al2O3, 0.2 wt %-0.8 wt % of micro-V powder and the balance of micro stainless steel powder. The stainless steel powder includes 0.08 wt % of C, 0.5 wt % of Si, 1.46 wt % of Mn, 0.03 wt % of P, 0.005 wt % of S, 19 wt % of Cr, 9.5 wt % of Ni, 0.5 wt % of Mo and the balance of Fe. The micro and nano powders are mixed through ball milling and mixed with anhydrous ethanol. The composite powder is suitable for laser repair of tiny crack on the surface of stainless steel part with high toughness requirement. After laser repair, the composite powder can be fused with the substrate, the repaired layer and the substrate are metallurgically bonded at the interface, the repaired layer contains fine grains, and therefore the compatibility and fracture property of the repaired layer are improved.
US11027332B2	System and method for in-situ characterization and inspection of additive manufacturing deposits using transient infrared thermography Systems and methods are provided for the real time inspection of additive manufacturing deposits using infrared thermography. Various embodiments may enable the measurement of material properties and the detection of defects during the additive manufacturing process. Various embodiments may enable the characterization of deposition quality, as well as the detection of deposition defects, such as voids, cracks, disbonds, etc., as a structure is manufactured layer by layer in an additive manufacturing process. Various embodiments may enable quantitative inspection images to be archived and associated with the manufactured structure to document the manufactured structure's structural integrity.
US11027325B2	Hot-formed metal sheet and method of producing an opening in such a metal sheet A hot-formed metal sheet has a tensile strength Rm>1300 megapascal (MPa) and includes an opening which is produced by high-speed punching at a speed of a punch of more than 6 m/s in the absence of a counter holder of a contour matching a contour of the punch, with a smooth cut proportion of the cutting surface of the opening amounting to more than 50%.
US11027322B2	Tube product, tube bender and method for using same A system comprises a tube and a bender. The tube comprises a first cylindrical portion and a second cylindrical portion. An undulated portion is disposed between the first cylindrical portion and the second cylindrical portion. Alternatively, the tube can comprise a plurality of cylindrical portions and undulated portions. The bender comprises a plurality of L-shaped brackets and a plurality of U-shaped brackets, and further includes a driving rod subassembly.
US11027321B2	Device for scraping debris from metal wire A device and related method for removing debris from a metal wire formed by a process utilizing a lubricant is provided. The device includes at least two segments forming a passage through which the wire passes, each having a leading edge for stripping debris from the wire, and a resilient member positioned around the at least two segments and applying a force to the segments sufficient to cause contact between the leading edges and at least the debris on the metal wire passing through the passage. The method broadly includes the steps of moving the metal wire through a passage formed by a plurality of segments, contacting the wire moving through the passage using a leading edge of each of the at least two segments, and applying a force to the at least two segments to cause contact between the leading edge of each of the at least two segments and at least the debris on the wire passing through the passage.
US11027318B2	Autofeeder roller cleaning Inventive cleaning sheets contact the rollers of paper shredder autofeed mechanisms with cleaning material that is either moistened with a solvent or treated with a low tack adhesive—either of which remove dirt and contaminants from the rollers. In one embodiment the moistened cleaning material is attached to a rigid sheet sized to fit into the paper compartment of the shredder where the cleaning material is brought into contact with the feed roller. The shredder is operated which causes dirt to be transferred from the rollers to the cleaning material. Alternatively, the cleaning material can be attached to a flexible but impermeable sheet which is placed into the shredder. The shredder is operated and after the rollers are cleaned, they may grab the entire flexible sheet and shred it, thereby additionally cleaning the shredding mechanism.
US11027309B2	Disposable sealant fluid path assembly One general aspect includes a liquid dispenser with a mount having a mount aperture. A liquid flow path assembly is removably secured to the mount and has an inlet configured to receive liquid, an outlet configured to dispense liquid and a passageway fluidly coupling the inlet to the outlet. A third aperture apart from the inlet and the outlet is fluidly coupled to the passageway and forming a valve guide. The liquid flow path assembly is disposed on the mount to align the third aperture with the mount aperture. An elongated valve has a valve stem guided by the valve guide and extends through the third aperture and the mount aperture. A latch assembly secures the liquid flow path assembly to the mount.
US11027305B2	Accommodating means for a dispensing container The invention relates to a container receiving device (10) for a dispensing container (28), in particular dispensers for liquid media, comprising a housing (12) comprising four side walls (14, 16, 18) and a housing bottom (20) for receiving the dispensing container (28) and a housing lid (22), with a securing device (47) for the dispensing container (28), with the securing device (47) comprising a latch (50) movable between a locking position and a release position, with the latch (50) in the locking position being moved into a region above a wall of a dispensing container (25) located in the container receiving device (10), so that the dispensing container (28) is secured against removal from the container receiving device (10) and in the release position is moved, in particular pivoted, out of the region.
US11027303B2	System and method for dispensing fluid in response to a sensed property A system for dispensing fluid in response to a sensed property such as an ambient sound comprises a sensor for detecting one or more properties, a processing stage for determining if the one or more sensed properties is/are within a predetermined range and/or above and/or below a predetermined level and dispenser for dispensing a fluid into an area surrounding the system if the one or more sensed properties is/are determined by the processing stage to be within a predetermined range and/or above and/or below a predetermined level and/or value.
US11027296B2	Sprayer device with aerosol functionality—Flairosol In embodiments, aerosol-type devices are provided. The devices have a main body comprising a pressure chamber, with pressure piston and pressure spring, and a piston chamber which draws liquid from a reservoir and fills the pressure chamber as a user performs compression and release strokes. The piston chamber has both inlet and outlet valves. In a dispensing head a valve is provided to regulate the flow strength and preclude leakage. Once the liquid is sufficiently pressurized, it is dispensed by a user opening an activation valve, and spray can be abruptly stopped by closing the activation valve. In alternate embodiments, without an activation valve, once the liquid is pressurized, continuous spray occurs until the pressure chamber is fully emptied. Pumping the trigger before the pressure chamber is fully emptied achieves continuous spray. When the input volume is greater than the volume of the pressure chamber volume, continuous spray with fewer pumping strokes occurs.
US11027295B2	Spray applicator A spray applicator assembly discharges distributable product from a cartridge using low air pressure. The cartridge is held captive between a piston advancing from the rear to expel contents and a nozzle snugly attached at the front to receive expelled contents and to convert the contents into droplets by subjecting the contents to an array of focused high velocity air streams. The nozzle has an open barrel design and is able to discharge a variety of liquid or viscous distributable product without readjustment, other than resetting a proportioning valve in the low pressure air feed line. An air chamber immediately in front of the cartridge nose provides constant backpressure, which dominates to cleanly stop flow of distributable product into the nozzle whenever the piston stops advancing. When the piston resumes advancement, the flow restarts cleanly. Clean stopping and starting saves distributable product from waste. Variations in the distributable product might include, without limitation, a broad variety of materials including coating materials and combustibles.
US11027294B2	Airborne material spreading assembly and method for spreading material A spreading assembly is provided. The spreading assembly comprises a spreadable material container, a spreading mechanism, and a motor. The spreading mechanism is rotatably mounted to a bottom section of the material container and can disperse the spreadable material 360° around the spreading assembly. The motor is operatively connected to the spreading mechanism to engage same in rotation. The spreading assembly comprises a coupling assembly to engage the spreading assembly with an unmanned aerial vehicle (UAV) configured to transport the spreading assembly while it operates.
US11027293B2	Nozzle for dispensing system A fluid dispensing nozzle includes a housing including an outlet to discharge fluid to a surrounding environment. The fluid dispensing nozzle also includes a nozzle insert disposed in the housing and including an inlet in fluid communication with a source of fluid to receive a fluid flow. The nozzle insert includes an outlet orifice in fluid communication with the outlet to direct fluid from the inlet toward the outlet. The nozzle insert is selectively movable relative to the housing between a first position in which fluid is discharged through the outlet at a first flow rate and a second position in which the fluid is discharged through the outlet at a second flow rate larger than the first flow rate. The nozzle insert is movable between the first position and the second position independent of the pressure of fluid at the inlet.
US11027292B2	Double filter with pass-through and method for dynamically compensating for the inlet fluid contamination A multiple-fluidic circuit substrate structure with an integral inter-circuit bypass lumen effectively provides multiple parallel filtered fluid inlets having filtered fluid outlets with at least one inter-circuit pass-through channel in fluid communication between the filtered fluid outlets to automatically provide full flow of filtered fluid to each of a plurality of fluidic circuits or to two or more circuits even if one fluidic circuit's corresponding inlet fluid filter is clogged.
US11027291B2	Separation disc for a centrifugal separator having spacing members with a triangular shape A separation disc for a centrifugal separator is adapted to be included in a stack of separation discs inside a centrifugal rotor for separating a fluid mixture. The separation disc has a truncated conical shape with an inner surface and an outer surface and a plurality of spot-formed spacing members extending from at least one of the inner surface and the outer surface. The spot-formed spacing members are for providing interspaces between mutually adjacent separation discs in a stack of separation discs, and the plurality of spot-formed spacing members are tip-shaped and taper from a base at the surface of the separation disc towards a tip extending a height from the surface. A stack of separation discs, a centrifugal separator and a method for separating at least two components of a fluid mixture are also disclosed.
US11027290B2	Centrifugal separator having an intermittent discharge system with hydraulically operated sliding bowl bottom A centrifugal separator for separation of at least two components of a fluid mixture of different densities includes a centrifuge rotor with a sliding bowl bottom movable between a closed position, in which the peripheral ports are closed, and an open position, in which the peripheral ports are open, an inlet channel for supplying hydraulic fluid to a closing chamber between the sliding bowl bottom and the rotor casing in order to hold the sliding bowl bottom in the closed position. The centrifugal separator includes at least one hermetic seal at a second end, other than the first end, of a hollow spindle and the inlet channel for supplying hydraulic fluid to the closing chamber extends through the hollow spindle and is arranged such that the hydraulic fluid is in thermal contact with the at least one hermetic seal when the hydraulic fluid is supplied to the closing chamber.
US11027288B2	Device and method for magnetic separation The invention relates to an apparatus for removing magnetizable particles in a substance, the apparatus comprising a magnetic separation chamber for filtering magnetizable particles and flocs from the substance, wherein the magnetic separation chamber comprises a first housing that defines a first space through which the substance can flow, as well as at least one first magnet of which a first magnetic field reaches into the first space, and which first magnet is located within a first holder that has an interface with the first space; and a flocculation chamber for inducing flocculation of the particles in a substance, the flocculation chamber being in fluid connection with the magnetic separation chamber; wherein the magnetic separation chamber is located downstream of the flocculation chamber, and wherein the flocculation of the magnetizable particles results in magnetizable flocs, and the magnetic field of the first magnet causes the magnetizable flocs to be attracted towards the first magnet, thereby removing the flocs of magnetizable particles from the substance.
US11027283B2	Magazine insert for a pneumatic tube conveyor capsule for receiving sample tubes, and pneumatic tube conveyor capsule having such a magazine insert A magazine insert for a pneumatic tube conveyor capsule for receiving sample tubes filled with bodily fluids includes a magazine drum, a fastening unit, a slider and a catch element. The magazine drum has a plurality of receiving chambers for the sample tubes. The fastening unit is pivotable about the longitudinal axis from a fastening position to a release position. The slider in the central recess of the magazine drum is slidable in axial direction from a first functional position bidirectionally to a respective second functional position relative to the magazine drum. The catch element is fastened to the slider and extends in radial direction into a control cam of the fastening unit. A pivoting of the fastening unit from the fastening position to its release position can be effected by transferring the slider to its corresponding second functional position.
US11027282B2	Digital to biological converter The present invention provides a system for receiving biological sequence information and activating the synthesis of a biological entity. The system has a receiving unit for receiving a signal encoding biological sequence information transmitted from a transmitting unit. The transmitting unit can be present at a remote location from the receiving unit. The system also has an assembly unit connected to the receiving unit, and the assembly unit assembles the biological entity according to the biological sequence information. Thus, according to the present invention biological sequence information can be digitally transmitted to a remote location and the information converted into a biological entity, for example a protein useful as a vaccine, immediately upon being received by the receiving unit and without further human intervention after preparing the system for receipt of the information. The invention is useful, for example, for rapidly responding to viral and other biological threats that are specific to a particular locale.
US11027281B2	Instrument for performing a diagnostic test on a fluidic cartridge A cartridge reader controlled by processing means for carrying out a diagnostic test on a sample contained in a fluidic cartridge comprises a mechanical valve for isolating the sample with the cartridge. A system for actuating the mechanical valve comprises an actuation member configured to move the mechanical valve from an open position to a closed position and an armature connected to the actuation member. The armature is configured to engage an electromagnet, wherein the electromagnet can be switched between an active state in which it electromagnetically holds the armature and an inactive state in which it does not electromagnetically hold the armature. First biasing means are disposed between the actuation member and a bearing surface, wherein the first biasing means is configured to bias the actuation member into a first position in which it actuates a mechanical valve in a fluidic cartridge inserted into the reader.
US11027269B2	Plugged honeycomb structure A plugged honeycomb structure, including: a plurality of honeycomb segments, a bonding layer and a circumferential wall disposed to surround circumference of a honeycomb segment bonded body where the plurality of honeycomb segments are bonded, wherein in the bonding layer, the bonding layer at a part that bonds the honeycomb segments disposed in contact with the circumferential wall is a circumferential bonding layer, and the bonding layer at a part that bonds the honeycomb segment including a center of gravity in a cross section orthogonal to the extending direction of cells of the honeycomb segment bonded body or at a position closest to the center of gravity and another honeycomb segment adjacent to the honeycomb segment is a center bonding layer, and a bonding strength A1 of the circumferential bonding layer is larger than a bonding strength A2 of the center bonding layer.
US11027266B2	Phosphorous acid P,P′-[5,5′,6,6′-tetramethyl-3,3′-bis(l- methylethyl)[1,1′-biphenyl]-2,2′-diyl] P,P,P′,P'-tetrakis(2,4-dimethylphenyl) ester in hydroformylation The compound of the formula (1) and its complexes with metal cations are used for catalysis in hydroformylation processes.
US11027265B2	SCR catalyst A copper-CHA zeolite catalyst for SCR of NOx is disclosed.
US11027264B2	Fluid catalytic cracking catalysts for increasing butylene yields A microspherical fluid catalytic cracking catalyst includes zeolite, and alkali metal ion or alkaline earth metal ion.
US11027261B2	Functionalized hybrid nanotube C@MoS2/SnS2 and preparation method and application thereof The invention discloses a functionalized hybrid nanotube C@MoS2/SnS2 and preparation method and application thereof. Dissolving ammonium molybdate tetrahydrate in water under ultrasound, adding ethylenediamine with stirring, and then adding dilute hydrochloric acid dropwise to react to obtain MoO3-EDA nanowires; adding L-cysteine and glucose into water containing MoO3-EDA nanowires, and obtaining a dispersion by ultrasonication; heating the dispersion and then centrifuging, then drying the solid matter and then calcining to obtain C@MoS2 nanotubes; adding C@MoS2 nanotubes into water containing SnCl4.5H2O and KSCN, and hydrothermally reacting to obtain functionalized hybrid nanotubes C@MoS2/SnS2. The invention realizes photocatalytic reduction of heavy metal ions to achieve treatment of heavy metal ion solution.
US11027259B2	Preparation method for hollow molybdate composite microspheres and method for catalyzing ammonia borane hydrolysis to produce hydrogen A method of preparing hollow molybdate composite microspheres includes steps of: (1) dissolving 1-4 mmol of MCl2 in 20 ml of water to obtain a solution A and dissolving 1-4 mmol. of molybdic acid in 20 ml of water to obtain a solution B, followed by mixing the solution A and the solution B, in which M is Co, Ni, or Cu; (2) dissolving 10-40 mmol of urea in 40 ml of water, adding the mixed solution of step (1) and stirring uniformly; (3) placing the mixed solution of step (2) into a reaction vessel and reacting at 120-160° C. for 6-12 hours; (4) suction filtrating and water washing, followed by drying in a vacuum oven at 40-60° C.; (5) calcination at 350-500° C. for 2-4 hours in a Muffle furnace.
US11027258B2	Copper nanoparticle-titania composite nanoarchitectures A composition having: titania aerogel having titania nanoparticles and copper nanoparticles. Each of the copper nanoparticles is in contact with more than one of the titania nanoparticles. A method of: providing a titania aerogel, and forming or depositing copper nanoparticles onto the surface of the titania aerogel.
US11027257B2	Polycalixarene materials, methods of making same, and uses thereof Provided are porous polymeric materials, methods of making same, and methods of using same. The porous polymeric materials include crosslinked calixarene moieties. The porous polymeric materials can be added to a sample and absorb/adsorb pollutants present in the sample. The absorbed/adsorbed pollutant can further be isolated from the porous polymeric material. The porous polymeric materials can be recycled.
US11027252B2	Reactor for continuous production of graphene and 2D inorganic compounds Provided is a continuous reactor system for producing graphene or an inorganic 2-D compound, the reactor comprising: (a) a first body comprising an outer wall and a second body comprising an inner wall, wherein the inner wall defines a bore and the first body is configured within the bore and a motor is configured to rotate the first and/or second body; (b) a reaction chamber between the outer wall of the first body and the inner wall of the second body; (c) a first inlet and a second inlet disposed at first end of the reactor and in fluid communication with the reaction chamber; (d) a first outlet and a second outlet disposed downstream from the first inlet, the outlets being in fluid communication with the reaction chamber; and (e) a flow return conduit having two inlets/outlets in fluid communication with two ends of the reactor.
US11027246B2	Closed concentrated dry chemical dispersion system and method A closed concentrated dry chemical dispersion system including a closed ingredient container having a volume of dry ingredient therein. The system provides a fluid container and a mixing chamber in which the dry ingredient and fluid can be mixed to form a formulation for delivery to a device such as agrochemical dispensing equipment. The system minimizes worker exposure to the chemicals and enables lower packaging and transportation costs.
US11027245B1	Process for continuous dissolution of a solid in a reaction medium A process for continuous dissolution of a solid in a reaction medium includes: (a) providing a liquid by withdrawal of a portion of the reaction medium from a first reaction vessel; (b) contacting the liquid provided in (a) with the solid in a second reaction vessel to form a solution of the solid; and (c) recycling the solution formed in step b) into the first reaction vessel. The solid in the second reaction vessel is present in the form of a fixed bed which is traversed by the liquid.
US11027243B2	Grafted islands-in-the-sea nonwoven for high capacity ion exchange bioseparation The invention provides polymer-grafted and functionalized nonwoven membranes adapted for use in bioseparation processes, the membranes including a nonwoven web of polyester fibers having an average fiber diameter of less than about 1.5 microns, each of the plurality of polyester fibers having grafted thereon a plurality of polymer segments constructed of a methacrylate polymer, each polymer segment carrying a functional group adapted for binding to a target molecule. The invention also provides a method of bioseparation comprising passing a solution comprising the target molecule, such as a protein, through the nonwoven membrane of the invention such that at least a portion of the target molecule in the solution binds to the nonwoven membrane. A method for preparing a polymer-grafted and functionalized nonwoven membrane adapted for use in bioseparation processes is also provided.
US11027242B2	Nanofiltration membranes and methods of use The present invention provides nanofiltration membranes with reduced chemical reactivity that can be utilized in manufacturing processes where reactive feedstocks and/or products are utilized or produced. Methods of making and using the membranes are also provided.
US11027237B2	Direct injection of aqueous urea This disclosure provides an apparatus and method for reducing emissions of nitrogen oxides (NOx) from a combustion source. For example, a method and apparatus for injecting a urea solution directly into the flue gas stream of a coal-fired power plant that utilizes Selective Catalytic Reduction (SCR) to lower NOx emissions.
US11027233B2	Absorption rotor, rotor element, method of manufacturing absorption rotor, and method of manufacturing rotor element The present invention is to prevent an absorption member from dropping off while reducing damage to the absorption member. An absorption rotor includes plural spokes extending in a radial manner from the circumference of the rotation axis, a tubular rim 4 coupling end portions of the plural spokes, an absorption member accommodated in a space which is surrounded by the plural spokes and the rim, the absorption member that absorbs a substance to be absorbed when a gas passes through, and a drop-off prevention member respectively fixed to the spoke and the absorption member, the drop-off prevention member that prevents the absorption member from dropping off the spoke. The drop-off prevention member is arranged between the absorption member and the spoke, and between a surface from which the gas flows into the absorption member and a surface from which the gas flows out of the absorption member.
US11027230B2	Filter holding frame A filter holding frame that may be used agricultural environments. The filter holding frame may include a plurality of interconnecting members with an upstream hemmed edge and downstream opposing flanges. The opposing flanges of the members may define a sealing face configured for a plurality of air filters. The members of the outer periphery of the filter holding frame may include the mounting surface and the sealing face.
US11027227B2	Treatment device for treating fluids, in particular liquid fluids, and treatment element of treatment device A filter device for treating fluids, in particular for filtering fluids such as fuel, oil, or water, has a housing (56) with a housing pot (58), a housing cover (60), at least one inlet (88) for the fluid to be treated, and at least one outlet (82) for the treated fluid. A connecting head (12) has at least one feed (16) for the fluid to be treated and connectable to the at least one inlet (88), and/or at least one discharge (18). The connecting head (12) and the treatment element (14) can be connected to each other by means of a releasable bayonet-type connecting device (34) through the execution of a rotational/plug-in movement about a connecting axis (20) of the treatment device (10).
US11027226B2	Tray unit for a wastewater treatment device and a method of assembling a tray assembly for a wastewater treatment device There is described a tray unit for a wastewater treatment device. The tray unit has a substantially frusto-conical profile defining an axis and a central aperture. The tray unit comprises a plurality of distinct tray sections arranged around the axis. Each tray section comprises a portion of the substantially frusto-conical profile of the tray unit and is connectable to one or more of the other tray sections so as to form the tray unit. There is also described a method of assembling a tray assembly for a wastewater treatment device. The method comprises the steps of: providing a plurality of tray units, the tray units each having a substantially frusto-conical profile and a central aperture and comprising a plurality of connecting lugs each defining a hole; attaching a first one of the tray units to a plurality of support members by inserting the support members through the hole of the connecting lug of the first tray unit and securing the first tray unit to the support member; and attaching a second one of the tray units to the plurality of support members by inserting the support members through the hole of the connecting lug of the second tray unit and securing the second tray unit to the support member to form an assembly of tray units.
US11027222B2	Apparatus and method for gravitational separation of the phases of a two phase liquid Disclosed is an apparatus for the gravitational separation of the first and second liquid phases of a two phase liquid containing predominantly a continuous first liquid phase with a dispersed second liquid phase having a lower specific gravity than the first liquid. The apparatus comprises a tank defining an interior chamber. A feed inlet introduces the two 5 phase liquid into the lower portion of the chamber. The upper portion of the chamber has an upward flow zone through which the two phase liquid rises, with the dispersed second liquid rising more than the first liquid and being separated therefrom due to the second liquid's lower specific gravity. The second liquid forms a floating layer and a conduit directs separated second liquid from the floating layer to a second liquid outlet.
US11027217B2	Electrically controlled nucleation and crystallization Disclosed herein are systems and methods for the controlled crystallization of a compound. The controlled crystallization is achieved by applying an electric field across solutions of target compound and precipitant, whereby the electric field controls the rate of mixing.
US11027215B1	Vacuum distillation apparatus and methods Vacuum distillation apparatus and methods are provided. In an embodiment, an apparatus is provided that includes an evaporation chamber having a bottom flow rate control (FRC) surface that is curved to provide multiple flow rates to a solution as it flows across the bottom surface. The apparatus also includes a wiper that is curved to match the curve of the bottom FRC surface and wipes the bottom FRC surface to distribute the solution. A heater heats the bottom FRC surface to evaporate one or more components from the moving solution.
US11027214B2	Magnetic construction toy Magnetic construction toy refers to engaging games and may be used to assemble three-dimensional figures. The magnetic construction toy contain elements in the form of polyhedrons with magnets placed inside each face and the elements are made in the form of tetrahedron, or octahedron, or cube, or other similar forms.
US11027212B2	Kart with movable visual effect A ridable kart having a front portion rotatably coupled to a rear portion. The front portion includes an inner surface that is adjacent to an outer cover portion and the two surfaces move relative to one another. The outer cover portion includes window portions or openings through which a portion of the inner surface is visible. The inner surface includes a visual feature that is visible through the window portions and the visual features moves relative to the window portions when the front portion rotates relative to the rear portion.
US11027210B2	Motion generating platform assembly An inverted Stewart platform assembly includes a first platform having a first surface, a second platform having a second surface facing the first surface of the first platform, and six legs extending between and coupling the first platform and the second platform. The six legs are configured to be actuated between a first arrangement in which adjustable lengths of the six legs, measured from the first platform to the second platform, are substantially equal to one another, and a plurality of second arrangements in which the adjustable lengths of the six legs are not substantially equal to one another, wherein each leg of the six legs forms, in the first arrangement, an angle of less than or equal to 45 degrees with a plane defined by the first platform.
US11027209B2	Amusement ride A visitor compartment equipped with a system of screens, an audio system, a lighting system, a controller, a control console, a video monitoring system and a payment system, the compartment is made in the form of an elevator car having sliding doors and connected to a pneumatic cylinder and compressor for moving, a wall or walls, the ceiling has cells with animatronic objects connected to movement mechanisms and moving panels, the car is equipped with a water-spray device, a device for the supply of directed air flows, a photo camera and/or video camera, a safety and emergency stop system of the amusement ride. The elevator car is equipped with a steam generator and/or smoke machine, a forced air ventilation system, a soap bubble generator, a spark generator. The system of screens is equipped with a holographic projector. The photo camera and/or video camera are connected to the Internet for sending the photo and/or video to the visitor by e-mail or for publication in social networks during the amusement ride.
US11027206B2	Multi-device gaming interface An electronic device may be configured to present a user interface via which a user can select from a plurality of commands associated with a particular video game. In response to a selection of one of the plurality of commands, the electronic device may transmit the selected one of the plurality of commands to a user interface device. The selected command may cause said user interface device to transmit a corresponding one or more simulated user inputs to a game console. The selection of the command may occur automatically in response to detection, by audio processing circuitry, of an occurrence of the particular audio clip in an audio signal output by the game console.
US11027203B2	Game system and game providing method using the system A game system capable of more easily recruiting game players and a game progress method using the game system is disclosed. The game system includes: a game server providing an online game; an external server for providing a communication service; a recruiting user terminal creating a party of the online game, transmitting the generated party to the game server, creating a party member recruitment announcement including information on a participation condition of the party, and transmitting the party member recruitment announcement to the external server; and at least one participating user terminal receiving the party member recruitment announcement from the external server and transmitting user game information for participating in the party to the game server in response to the received party member recruitment announcement.
US11027201B2	Composing an image The invention relates to a computer implemented method for controlling the display of a tile image on a display of the computer device, the method comprising: storing in a computer memory at the computer device, image texture data comprising a plurality of sets of predefined masks, each set of predefined masks for forming a respective tile image; selecting at random a tile image for display from a plurality of tile images; determining a location of each mask in the set of predefined masks for forming the selected tile image, in the image texture data; and supplying an indication of said location to a shader program executed on the computer device to control the shader program to use the set of predefined masks to form the selected tile image on said display.
US11027197B2	Serverless gaming through zero-knowledge proofs A method for processing a serverless video game includes generating, at a first node, a notification to a second node to join play of the serverless video game, and confirming, by the first node, that the second node has joined to play. The joining by the second node creates a peer-to-peer communication process for executing an application layer for the serverless video game. The method also includes executing, at each of the first node and the second node a consensus algorithm for verifying moves processed by the application layer that runs game rules for the serverless video game. The consensus algorithm is configured to independently process at each of the first and second nodes the verifying of the moves. In one example, the consensus algorithm of each of the nodes is configured to process one or more zero-knowledge proofs for verifying moves made during play of the serverless video game.
US11027195B2	Information processing apparatus, information processing method, and program There is provided an information processing apparatus, an information processing method, and a program that enable a predetermined haptic stimulus to be presented to a number of corresponding input devices on the basis of inputs from the input devices and thereby realize an intuitive haptic interface that gives a deeper sense of realism. The information processing apparatus includes: an acquisition unit configured to acquire a plurality of pieces of pointer information on the basis of one or a plurality of pieces of sensor data; a discrimination unit configured to discriminate an input device corresponding to each pointer on the basis of characteristics of the plurality of pieces of pointer information; and a generation unit configured to generate a predetermined haptic stimulation signal to be output to an input device corresponding to a pointer in a case in which a position of the pointer satisfies a predetermined condition.
US11027194B2	Force feedback to improve gameplay Force feedback is applied to a computer simulation controller, such as to a joystick element or analog trigger of the controller, depending on the context of the simulation.
US11027189B2	Entertainment method for self-driving vehicle An entertainment device and method for a self-driving vehicle enable a passenger to play a game while watching a game execution screen of a display mounted around a seat in a state where the passenger is seated on the seat of a self-driving vehicle, and execute and proceed with the game based on a signal that senses a body pressure distribution of the passenger in a body pressure sensor mounted on the seat, and a signal that senses the touch pressure of the passenger in a touch pad mounted on the seat, thereby allowing the passenger to enjoy various games related to the body pressure and/or the touch signal while the passenger moves his or her body.
US11027188B2	Rotation powered vehicle Device and method embodiments for a rotation powered vehicle are described, the rotation powered vehicle being capable of converting a rotational motion of a platform pivotally secured to the rotation powered vehicle in either of two angular directions into a linear motion of the rotation powered vehicle in a single linear direction for the purposes of conveyance. In some cases, the angular motion of the platform may be slight when compared to the resultant linear powered stroke of the rotation powered vehicle.
US11027174B2	Multi-piece solid golf ball In a multi-piece solid golf ball having a core, an envelope layer, an intermediate layer and a cover, the core is formed primarily of a base rubber and has a diameter set in a specific range, the envelope layer, intermediate layer and cover are each formed of resin materials, and the envelope layer is formed into two layers—an inner layer and an outer layer. The center and surface hardnesses of the core, the surface hardness of the inner envelope layer-encased sphere, the surface hardness of the outer envelope layer-encased sphere, the surface hardness of the intermediate layer-encased sphere and the surface hardness of the ball together satisfy a specific relationship. This ball achieves a satisfactory distance on full shots both with a driver and with irons, in addition to which it is superior in the short game and has a good feel at impact and an excellent scuff resistance.
US11027173B2	Pool noodle, assembly, and method of use A water noodle system includes three water noodles and at least two water noodle straps. Each of the water noodles has an elongated body extending along a longitudinal axis and terminating at first and second ends. The elongated body defines a central bore therethrough that is axially aligned with the longitudinal axis, and an outer surface of the elongated body includes a plurality of protrusions extending therefrom and radially therearound. Each of the water noodle straps has an elongated strap body terminating at first and second ends, and first and second buckle portions affixed to the respective first and second ends of the elongated strap body. The first and second buckle portions are configured to mate with each other.
US11027169B2	Electric treadmill The present disclosure proposes an electric treadmill. The electric treadmill includes a base and an armrest. The base includes a front frame, a rear frame and a connecting assembly, wherein tread boards are provided within the front frame and the rear frame, and the front frame and the rear frame are hinged by the connecting assembly to enable the base to be folded. The armrest includes a vertical tube and a cross tube, wherein one end of the vertical tube is connected to the cross tube and the other end of the vertical tube is rotatably coupled to the base to allow the armrest to be foldable with respect to the base. The front frame and the rear frame may be folded with respect to each other, thus, a length of the base is greatly reduced for storage.
US11027168B2	Manual treadmill which can be set to an exercise speed The present disclosure regards a manual treadmill. The manual treadmill includes a continuous belt coupled to a frame and adapted for an operator walking or running thereon; a sensing apparatus, sensing a parameter and producing a corresponding speed signal corresponding to a current rotating speed of the continuous belt; an inputting apparatus, producing an indication signal corresponding to a target rotating speed of the continuous belt; a control unit, receiving the corresponding speed signal to get a current speed value, receiving the indication signal to get a target speed value, and producing a first control signal; and a resistance adjusting apparatus, producing a resistance to impede the rotation of the continuous belt; wherein the control unit controls the resistance adjusting apparatus using the first control signal to decrease (or increase) the resistance when the current speed value is lower (or higher) than the target speed value.
US11027155B2	Method for prevention and treatment of diabetic kidney disease A method for delaying the progression or preventing Diabetic Kidney Disease by administering to a subject in need a composition containing a therapeutically effective amount of a hyaluronan synthesis inhibitor such as 4-Methylumbelliferone.
US11027151B2	Particle arc therapy A method of delivering a particle beam at a target is disclosed. In implementations, the particle beam is delivered from an output device at a plurality of control points and the method comprises the step of delivering a substantially continuous particle beam about the plurality of control points.
US11027149B2	Hybrid ultrasound-guided superficial radiotherapy system and method Systems, method and devices for detecting, analyzing and treating lesions, such as skin cancer are disclosed. Such a system can include a high-frequency ultrasound imaging device to image a lesion. The system can also include a processor that executes instructions stored in memory to perform operations, and the operations can include receiving a plurality of images of the lesion from the high-frequency ultrasound imaging device, rendering a three dimensional model of the lesion using the plurality of images from the high-frequency ultrasound imaging device and determining a treatment dosimetry based on the three dimensional model of the lesion. The system can also include a radiotherapy device to provide radiotherapy treatment to the lesion, where the radiotherapy treatment is based on the treatment dosimetry.
US11027145B2	Laser induced ballistic particle implantation technique A method using a receiving substrate and a target substrate having a photon-transparent support, a photon absorbent interlayer coated on the support, and a tissue-implantable particle on top of the interlayer opposite to the support. A source of photon energy is directed through the transparent support so that the photon energy strikes the interlayer. A portion of the interlayer is energized by absorption of the photon energy. The energized interlayer causes a transfer of the particle across a gap between the target substrate and the receiving substrate and embedding of the particle into the receiving substrate.
US11027140B2	Self-powered, auto-responsive implanted vagal nerve stimulator for weight control The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge without the need for a battery. In this regard, the invention is self-powering and is automatically timed to stomach peristalsis. While sporadic stimulation to the vagal nerve would seem too infrequent to cause weight loss effects, electrical stimulation delivered at the optimal time (e.g., during food consumption) has been found to optimize the effects of vagal nerve stimulation, giving the user's brain a “full stomach” signal before the user over-consumes food.
US11027134B2	Active implantable medical device such as a cardiac resynchroniser with dynamic adaptation of an atrioventricular delay depending on a detected and quantified degree of fusion This disclosure relates to an active implantable medical device of the cardiac resynchronizer type. The device includes a pulse generator to produce pacing pulses, at least one detection electrode for detecting atrial and ventricular events, at least one stimulation electrode, a memory storing executable instructions, and a processor configured to execute the instructions. The processor is configured to execute the instructions to apply an atrioventricular delay (AVD) between a sensed or stimulated atrial event and the delivery of a ventricular pacing pulse, quantify a degree of fusion between the delivery of a pacing pulse to a cavity and a spontaneous contraction of another cavity, calculate a fusion rate, and modify the value of the AVD applied to the delivery of said ventricular pacing pulse, as a function of a comparison.
US11027131B2	Use of a new stimulation design to treat neurological disorders The method and system described herein relate to stimulating nerve tissue using a pulse generator. A stimulus is created that comprises a signal that is produced from a frequency spectrum having a power spectral density per unit of bandwidth proportional to 1/fβ, wherein β is excludes 0. The stimulus is provided from the pulse generator to at least one stimulation lead; and applied to nerve tissue via one or several electrodes.
US11027129B2	Patient-customized electrode arrays based on patient-specific cochlear information, and designing/selecting methods and applications of same A method for designing a patient-customized EA or selecting an existing EA that fits the patient best includes segmenting shapes of SOIs of the cochlea in a pre-operative CT image using a shape model; defining a 3D curve of interest within the shape model of the SOIs as a sequence of points-; automatically transforming the defined 3D curve to the pre-operative CT image so as to obtain a structure curve in the cochlea; determining a length and curvatures of the structure curve at the sequence of points; and designing a patient-customized EA or selecting an existing EA based on the determined length and curvatures of the structure curve such that after the EA shape model, which estimates the resting state shape of the EA, is rigidly registered to the structure curve in the cochlea, the EA shape model has a registration error smaller than a preset value.
US11027128B2	Device for non-invasive electrical stimulation of the spinal cord A device for the noninvasive stimulation of the spinal cord, intended for carrying out diagnostic tests and physiotherapy. A spinal cord electrostimulator includes five stimulation channels with an electrode system, each of the channels includes connected in series a voltage converter, a current generator and an output signal generator and it is configured to be able to generate the following rectangular pulses: rhythmic modulated bipolar, rhythmic modulated monopolar, rhythmic non-modulated monopolar, single non-modulated monopolar. The inputs of each of the channels are coupled to a microcontroller, which is connected to an indication unit, a control unit and a radio module. The microcontroller is configured to trigger at least one said channel, to select a triggering mode independently for each of the channels, to control each of said channels with parameters of the pulses and vary said parameters depending on a degree of damage to a spinal segment.
US11027122B2	Spinal cord stimulation method to treat lateral neural tissues A method assists a person by providing an electrode array having a substrate supporting a plurality of stimulation contacts configured to stimulate at least a portion of the spinal cord neural tissue. The method also implants, in a medically uncompressed manner, the therapy array in the epidural space, where a portion of the therapy array is positioned adjacent to at least one pedicle with stimulation contacts positioned adjacent to at least one dorsal root laterally and at least one fasciculi of the dorsal column within the vertebral foramen at one or more vertebral levels.
US11027118B2	Gel dispenser for electrodes A device for electrical stimulation of a user is disclosed. The device includes an electrode for applying an electrical stimulation and a gel or liquid dispensing system. The electrode is attached to a first side of a garment such that a surface of the electrode is placed in contact with a portion of a user's skin when the garment is worn by the user. The gel or liquid dispensing system is attached to the garment and configured to be actuatable to dispense a gel or liquid onto the surface of the electrode, the dispensing system having a reservoir configured to hold the gel or liquid and a fluid passageway extending from the reservoir to the surface of the electrode. The electrode may be a carbon or carbon equivalent electrode.
US11027117B2	Resilient head mounted device for neurostimulation and sensing of body parameters A headset for use in delivering electrical stimulation to the skin surface of the head or in sensing one or more body parameters of the head of a user.
US11027113B2	Implantable mechanical circulatory support devices A mechanical circulatory support device. The mechanical circulatory support device includes an inner casing defining a fluid flow path, the fluid flow path defines a longitudinal axis. A rotor is mounted within the fluid flow path and configured to rotate about the longitudinal axis. A housing is included, the inner casing and the rotor being substantially disposed within the housing. The housing having a cross-sectional shape in a plane transverse to the longitudinal axis which decreases in thickness extending from a medial position to opposite lateral positions.
US11027111B2	Connector system for releasably connecting fluid conduits Disclosed herein are embodiments of a connector system for releasably connecting together tubes, for example medical tubing, and methods of making and using such a connector system, whereby the connector system includes a female coupler having a first passageway, a male coupler having a second passageway, a catch movably coupled to the female coupler, and a catch-receiving element coupled to the male coupler. The connector system further includes a release element movably coupled to the female coupler, whereby travel of the release element along or over a female coupler outer surface of the female coupler disengages the catch from the catch-receiving element to achieve a disconnected condition of the connector system. Further disclosed herein are embodiments of a connector system for releasably connecting together tubes, whereby the connector system includes at least one valve biased by a valve-biasing member disposed external to or outside of the fluid flow path.
US11027108B2	Fluid transfer assembly with a junction having multiple fluid pathways A fluid transfer assembly is described. The fluid transfer assembly includes a unitary junction having an upstream portion and a downstream portion, the unitary junction defining a plurality of curved fluid pathways between the upstream portion and the downstream portion. The assembly also includes at least one flexible fluid conduit sealed to the junction in fluid communication with at least one of the plurality of curved fluid pathways.
US11027106B2	Dilating device and method for prostatic urethra A dilating device for the prostatic urethra comprising: Prostatic implant includes independently actuatable distal retractor incorporating and proximal retractor. Retractors may be connected via a spine member. System and method include implant manipulator detachably connected to implant, for manipulating and forcing implant into close proximity, for delivery into subject.
US11027105B2	Adjustable instrument for dilation of anatomical passageway An apparatus includes an instrument body, a shaft assembly, a dilation catheter, a guidewire, and a proximal deflection actuation assembly. The dilation catheter includes an expandable dilator and is slidable relative to the shaft assembly to thereby position the dilator distally relative to the distal end of the shaft assembly. The proximal deflection actuation assembly is positioned at the proximal end of the shaft assembly and is operable to selectively deflect the length of the shaft assembly relative to the longitudinal axis of the instrument body to thereby deflect the longitudinal axis of the shaft assembly away from the longitudinal axis of the instrument body.
US11027103B2	Conduit device and system for implanting a conduit device in a tissue wall Various embodiments of the present invention provide a conduit device including an attaching device configured for defining a helical pathway through a tissue wall and complementary ring in cooperation for securing the device within an aperture defined in the tissue wall. Some embodiments of the present invention further provide a system for implanting a conduit device in a tissue wall. More specifically, some embodiments provide a system including a coring device for defining an aperture in a tissue by removing and retaining a tissue core and securely implanting a conduit device therein so as to provide fluid communication between a first and second surface of the tissue wall via the conduit device.
US11027095B2	Archflo midline catheter A midline catheter is provided. The midline catheter includes a shaft defining a lumen, the shaft having a distal end and a proximal end. The distal end includes two or more opposing notches thereon, each of the notches having an open notch distal end and an opposing notch proximal end formed as an arch. The catheter may also include written indicia thereon to indicate that it is a midline catheter and/or is power injectable or non-power-injectable.
US11027092B2	System and methods for design, operation and use of the magnetic resonance of the earth for sleep enhancement A device for replicating a natural magnetic vibration of Earth, promoting more restful sleep. The device produces an appropriately uniform magnetic field across the surface of the area where the head rests during sleep. The device provides a varying magnetic field therapy that allows a user to sleep in their usual manner using their existing familiar pillow, with no changes to the aesthetics of the bed, while using the device having varying magnetic field therapy capabilities.
US11027084B2	Patient ventilating and aspirating system A patient ventilating (23) and aspirating system (8) is disclosed that has a suction tube (9) and connector (6) for connecting to a catheter mount that has a sealed passageway (15). The catheter mount passageway (15) is sealed with an elastomeric seal (16) including a perforation or slit (17). A connector (12) with a piercing member is associated with the suction tube (9). When the connector is attached to the catheter mount the piercing member (20) pierces the seal (16) such that the suction tube (9) can pass through the connector (6) and catheter mount.
US11027083B2	Pressure regulator for endotracheal tube cuff, breathing system comprising such a regulator and container comprising a variable volume chamber for such a regulator A pressure regulator includes a container defining a variable volume chamber having a least one first orifice to be connected to an auxiliary hose such that, in use, the variable volume chamber of the pressure regulator and a sealing cuff are in communication. The regulator includes a pressure means acting on the container for exerting a certain force by means of a weight that can move along an articulated rod for adjusting the air pressure contained in the variable volume chamber. A system for locking the weight is provided for preventing unexpected movement of the weight. The invention is applicable to endotracheal tubes, tracheotomy tube or similar instruments for the ventilation of a patient.
US11027082B2	Methods and systems to estimate compliance of a patient circuit in the presence of leak A method (200) for determining compliance of a connecting circuit in a non-invasive ventilator system. The method includes the steps of: (i) providing (210) a non-invasive ventilator system, the system having a flow or pressure controller; (ii) generating (220) a test signal for the flow or pressure controller; (iii) exciting (230) the flow or pressure controller with the generated test signal for a predetermined time period; (iv) obtaining (240), during the excitation of the flow or pressure controller, one or more measurements of the non-invasive ventilator system; (v) determining (250) a vector of the obtained measurements; and (vi) processing (260) the vector to determine an estimate of a physical parameter of the circuit.
US11027071B2	Intradermal jet injection electroporation device An jet injection and electroporation device for use with an agent cartridge defining a volume containing a pre-measured dose of agent therein, the electroporation device including a housing having an axis extend therethrough, a nozzle at least partially positioned within the housing, and a cavity sized to receive at least a portion of the agent cartridge therein. The device also includes an array having a plurality of electrodes extending therefrom, a propulsion cartridge configured to operatively engage the cartridge when the agent cartridge is positioned within the cavity; and a power supply in electrical communication with the array.
US11027068B2	Syringe support and autoinjector The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support includes a supporting beam arranged on the syringe support and biased radially inwards. The supporting beam is adapted to axially bias the syringe in a distal direction within the housing. The disclosure further relates to an autoinjector.
US11027055B2	Irrigation system comprising dual pumps An irrigation system is disclosed that can be uses in, for example, rectal irrigation. The system comprises a reservoir for an irrigating liquid and a probe for arrangement in a user. The probe includes an inflatable balloon for fixing the catheter in a body cavity. A first pump is provided to pump irrigation liquid from the reservoir to the probe, and a second pump is provided to pump a fluid to the balloon for inflation. A control unit controls the transfer of the irrigation liquid and the fluid, and includes a valve for releasing fluid from the balloon for deflation. Tubing provides fluid communication between the reservoir, control unit and probe. The control unit and the first and second pumps are further arranged as an integrated unitary component, and the manually operable balloon control element is arranged in the vicinity of the second pump.
US11027052B2	Systems and methods for priming fluid circuits of a plasma processing system Methods of priming a plasma processing system are disclosed. The plasma processing system has a number of different fluid flow circuits that are defined by sources of fluid, fluid flow paths, waste containers, a mixer, a separator, valves and a pump. A first fluid circuit is flushed, where the first fluid circuit is defined by a source of a first fluid, a first valve positioned between the source of the first fluid and the first fluid flow path, a second valve positioned between the first fluid flow path and the second fluid flow path, a first pump positioned between the second fluid flow path and the third fluid flow path, and a first waste container in fluid communication with the third fluid flow path. A second fluid circuit is then flushed by closing and opening certain valves.
US11027050B2	Reduced pressure tissue therapy device Disclosed herein are devices and methods for reduced pressure tissue therapy. Some variations of suction devices for reduced pressure tissue therapy comprise a housing, a suction force generating mechanism located within the housing, and a storage module configured to retain tissue exudates. In some variations, the storage module includes a sleeve configured to collect tissue exudates. The sleeve may include a support element to help maintain the lateral structural integrity of the sleeve and/or retain the cross-sectional geometry of the sleeve under negative pressure. In use, the storage module may reduce sanitary and/or biohazard risks by preventing the exudates from contacting the housing and/or suction force generating mechanism. The storage module is configured to be replaced so that the housing and suction force generating mechanism can be used for more than one session.
US11027049B2	Devices and methods for delivery of bioactive agents Embodiments of the invention include bioactive agent eluting devices. In an embodiment the invention includes a bioactive agent delivery device including a substrate, a hydrophilic polymer disposed on the substrate, and a substantially amorphous bioactive agent disposed on the surface of the hydrophilic polymer. In an embodiment, the invention includes a method of making a bioactive agent delivery device including depositing a hydrophilic polymer on a substrate forming a hydrophilic surface and depositing a substantially amorphous bioactive agent on the hydrophilic surface. In an embodiment, the invention includes a bioactive agent-eluting catheter including a catheter shaft and an expandable balloon disposed on the catheter shaft. Other embodiments are included herein.
US11027044B2	Method for producing sheet-like cell structure and sheet-like cell structure An object of the present invention is to provide a method for producing a sheet-like cell structure having excellent strength and shape-maintaining performance, and a sheet-like cell structure having excellent strength and shape-maintaining performance. According to the present invention, there is provided a method for producing a sheet-like cell structure, including: a step of adding a biocompatible macromolecular block, a cell, and a liquid medium onto a culture support body having a plurality of recessed portions on a culture surface, and immersing the biocompatible macromolecular block and the cell in uppermost portions of the recessed portions; and a step of culturing the cell to obtain a sheet-like cell structure.
US11027043B1	Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices One aspect of the present invention generally relates to methods of sealing a wound or tissue plane or filling a void splace. In a preferred embodiment, the wound is an ophthalmic, pleural or dural wound. In certain instances, the compositions used to seal the wound or tissue plane comprises a polyalkyleneimine. In a preferred embodiment, the polyalkyleneimine is polyethyleneimine. Treatment of the polyethyleneimine with a cross-linking reagent causes the polyethyleneimine polymers to polymerize forming a seal. In certain instances, the cross-linking reagent is a polyethylene glycol having reactive terminal groups. In certain instances, the reactive terminal groups are activated esters, such as N-hydroxy succinimide ester. In certain instances, the reactive terminal groups are isocyanates. In certain instances, the polyethyleneimine has a lysine, cysteine, isocysteine or other nucleophilic group attached to the periphery of the polymer. In certain instances, the polyethyleneimine is mixed with a second polymer, such as a polyethylene glycol containing nucleophilic groups. In certain instances, the compositions used to seal the wound or tissue plane are formed by reacting a polyalkyleneimine bearing electrophilic groups with a cross-linking reagent containing nucleophilic groups. In certain instances, the electrophilic groups on the polyalkyleneimine are activated esters, such as N-hydroxy succinimide ester. In certain instances, the compositions used to seal the wound or tissue plane are formed by reacting a polyalkyleneimine bearing photopolymerizable groups with ultraviolet or visibile light. Compositions used to seal the wound which contain PEI or a derivative of PEI are found to adhere tightly to the tissue. Other aspects of the present invention relate to methods of filling a void of a patient or adhering tissue. In certain instances, the methods use a polyalkyleneimine. In a preferred embodiment, the polyalkyleneimine is polyethyleneimine. Another aspect of the present invention relates to a polymeric composition formed by exposing a polyalkyleneimine to an activated polyalkylene glycol. In certain instances, the composition is attached to mammalian tissue.
US11027042B2	Antimicrobial hydrocolloid dressing containing sequestered peroxide and preparation thereof This disclosure provides a method of preparing a hydrocolloid adhesive that includes the steps of mixing one or more components to produce a continuous phase, heating the continuous phased to a predetermined temperature between about 135° C. to 170° C., adding a stabilizer to the continuous phase, reducing a temperature of the continuous phase to a second predetermined temperature below 99° C., adding a discontinuous phase to the continuous phase at the second predetermined temperature, and mixing the components of the discontinuous phase and the continuous phase to produce a uniform mixture. Further, the hydrocolloid adhesive includes a super absorbent material and 0.05% to 2% by weight of a peroxide.
US11027040B2	Method for manufacturing a porous film, porous film and method for tissue adhesion The present disclosure provides a method for manufacturing a porous film, including: preparing a polymer mixture solution, wherein the polymer mixture solution includes polycaprolactone and at least one hydrophobic polymer; adding solid particles as a dispersing agent to the polymer mixture solution and mixing the solid particles with the polymer mixture solution, wherein the amount of solid particles added is enough to convert the polymer mixture solution into a solid mixture; drying the solid mixture to form a film; and washing the film with a washing fluid to remove the solid particles from the film to form the porous film, wherein the weight ratio of the polycaprolactone to the at least one hydrophobic polymer is about 1:0.1-10, and wherein the weight ratio of the polycaprolactone and the at least one hydrophobic polymer to the solid particles is about 1:0.01-250.
US11027038B1	Fan for improving air quality A fan is for improving air quality, such as in an indoor environment. The fan includes a motor and a rotatable hub coupled to the motor. At least one fan blade includes a first end portion coupled to the rotatable hub and a second end portion radially distant from the rotatable hub. At least one ion generator is carried by the second end portion of the at least one fan blade, such as by a winglet associated therewith. A stationary tube passes through the rotatable hub including a conduit for transmitting power. A rotary coupling is also provided for transmitting power from the conduit to the at least one ion generator.
US11027036B2	Electronic scented candle and fragrance container An electronic scented candle is described that includes a movable flame-shaped component, a shell including an installation chamber, a fragrance container that is removably positioned inside the installation chamber and a scent chamber. An electric fan is positioned within the shell to drive the air into the scent chamber and a scent outlet coupled to the scent chamber to allow the fragrance material to leave the scent chamber and to reach an external environment of the electronic scented candle. The electronic candle also includes a receptacle for connecting a power cord on a bottom surface of the electronic candle. The bottom surface includes a plurality of protruding stands that provide a space to allow the power cord to be connected to the receptacle and be routed below the bottom surface.
US11027035B1	System, method for providing aromatherapy A pressed biomass component is disclosed. The pressed biomass component includes plant or animal material that is compressed by a press plate apparatus by application of pressure within a range of 1000 to 36000 pounds per square inch (PSI). The pressed biomass component is a resultant of the application of the pressure to the plant or animal material and typically has a weight of 0.5-10 grams. The pressed biomass component of claim 1 may be formed in a disc shape including a curved perimeter, a top surface and a bottom surface oriented in parallel with the top surface; thus, resembling a coin. The application of pressure to the press plate apparatus forms the pressed biomass component to support a desired burn time when placed on a heating apparatus. The heating apparatus often includes a ceramic bulb having a wattage within a wattage range of 50 w-150 w.
US11027034B2	Systems and methods for spraying of sanitizing or disinfecting compositions with improved compatibility This invention relates to systems, methods, and disinfecting compositions for spraying onto surfaces to be sanitized or disinfected. Methods may include providing an aqueous hypohalite disinfecting composition, and providing a spraying system that may include a hand-held spray nozzle through which the composition is sprayed during use, and a pump and associated tubing for conveying the composition to the hand-held spray nozzle. The tubing may be specifically selected to exhibit at least a 65% recovery (no more than 35% loss) of hypohalite after 24 hours of contact between the composition and the tubing. The method may further include conveying the composition from the reservoir to the spray nozzle, and spraying the composition through the nozzle, e.g., onto the target surface. A related system may include similar components. A dilute hypohalite disinfecting composition may be provided for use with the system and/or method. The system may allow interchangeable use of a quaternary amine disinfecting composition.
US11027033B2	Sterilizing apparatus A sterilizing apparatus is disclosed. A sterilizing apparatus according to one embodiment comprises: a cover main body unit having an accommodation space formed therein so as to accommodate a device to be sterilized, wherein the accommodation space is open toward a bottom surface on which the device to be sterilized is disposed; an ultraviolet light emitting diode provided on a surface facing the bottom surface of the cover main body unit, and turned on so as to emit ultraviolet rays toward the accommodation space; a power supply unit for supplying power to the ultraviolet light emitting diode so as to turn on the ultraviolet light emitting diode; and a control unit for controlling an operation of the power supply unit.
US11027029B2	Peptide thiourea derivative, radioisotope labeled compound containing same, and pharmaceutical composition containing same as active ingredient for treating or diagnosing prostate cancer The present invention relates to a peptide thiourea derivative, a pharmaceutically acceptable salt thereof, a radioisotope labeled compound comprising the same, and a pharmaceutical composition for treating or diagnosing prostate cancer comprising the same as an active ingredient. The peptide thiourea derivative of the present invention is excellent in stability in human serum when it is administered in vivo and not only binds well to PSMA expressed in prostate cancer but also inhibits excellently PSMA at a low concentration. Besides, the derivative of the invention has a high water-solubility and can be excreted through the kidney not through the bile passage so that a clear image of the tumor region of prostate cancer can be obtained. Therefore, the derivative of the present invention can be effectively used as a pharmaceutical composition for treating and diagnosing prostate cancer.
US11027025B2	Compositions comprising synthetic polynucleotides encoding CRISPR related proteins and synthetic sgRNAs and methods of use The present invention relates to compositions comprising and methods of using synthetic polynucleotides, e.g., modified mRNA, encoding CRISPR related proteins including dCAS9 and synthetic sgRNAs targeting a gene of interest.
US11027022B2	Conjugates and conjugating reagents A conjugate of a protein or peptide conjugated to a therapeutic, diagnostic or labelling agent via a linker, in which the linker includes a protein or peptide bonding portion having the general formula: in which Pr represents said protein or peptide, each Nu represents a nucleophile present in or attached to the protein or peptide, each of A and B independently represents a C1-4alkylene or alkenylene chain, and W′ represents an electron withdrawing group or a group obtained by reduction of an electron withdrawing group; and in which the linker also includes a cyclodextrin. The invention also provides reagents for making such conjugates.
US11027019B2	Methods of making antimicrobial biopolymer from sodium alginate and algae extract using aminoglycosides, and methods of using the same Methods of forming antimicrobial biopolymers from sodium alginate and algae extract using aminoglycosides are presented. Also presented are improved biopolymers, methods of making the biopolymers, and methods of using the biopolymers, wherein the biopolymer includes a sodium alginate and an aminoglycoside.
US11027018B2	Use of anti-CGRP antibodies and antibody fragments to treat diarrhea in subjects with diseases or treatments that result in elevated CGRP levels The present invention is directed to methods for treating diarrhea, both chronic or acute forms, by the administration of a therapeutically or prophylactically effective amount of antibodies and fragments thereof having binding specificity for CGRP. In particular the methods prevent or reduce diarrhea in conditions or treatments resulting in elevated CGRP levels, e.g., in the GI tract (colon) that are associated with diarrhea and/or improper electrolyte and fluid excretion from the bowel or urinary system. More specifically, this invention relates to treatments using the anti-CGRP antibodies and fragments described herein, and binding fragments thereof.
US11027017B2	PCI method for generating immune respose to antigenic molecule using checkpoint inhibitor and TLR3 ligand The invention concerns a method of generating an immune response in a subject, comprising administering to the subject an antigenic molecule, a photosensitizing agent, a checkpoint inhibitor, and irradiating said subject with light of a wavelength effective to activate the photosensitizing agent to generate an immune response. Preferably the method is a method of vaccination. The invention also provides related methods, compositions, cells, uses, products and kits.
US11027013B2	Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor The present invention concerns a pharmaceutical composition where a checkpoint inhibitor is combined with an oncolytic virus and the use of said combination for the treatment of cancer.
US11027008B2	Recombinant mumps virus vaccine The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/US/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to rMuVIowa/US/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuVΔSH) and/or incapable of expressing the V protein (rMuVΔV).
US11027007B2	Recombinant metapneumovirus F proteins and their use Metapneumovirus (MPV) F proteins stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the MPV F proteins and/or nucleic acid molecules can be used to generate an immune response to MPV in a subject. In additional embodiments, the therapeutically effective amount of the MPV F ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing MPV infection.
US11027003B2	HLA-DR-binding antigen peptide derived from WT1 The present invention provides a WT1-derived HLA-DRB10405-binding antigen peptide, a polynucleotide encoding said peptide, a helper T cell inducer comprising said peptide or polynucleotide, and the like. It is related to a partial peptide consisting of 10-25 contiguous amino acids in the amino acid sequence of human WT1 shown in SEQ ID NO: 1, which binds to HLA-DRB10405 and induces helper T cells, a polynucleotide encoding said peptide, or a helper T cell inducer comprising said peptide or polynucleotide.
US11027000B2	AADC polynucleotides for the treatment of Parkinson's disease The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
US11026999B2	Insulin glargine/lixisenatide fixed ratio formulation The present invention refers to a pharmaceutical composition comprising (a) lixisenatide or/and a pharmaceutically acceptable salt thereof, and (b) insulin glargine or/and a pharmaceutically acceptable salt thereof, wherein the compound (b) and compound (a) are present in a fixed ratio.
US11026998B2	Shaped mass composition comprising exenatide Embodiments of the invention provide shaped masses comprising one or more drugs such as proteins or polypeptides and methods for forming such shaped masses. One embodiment provides a shaped mass comprising a drug such as a protein or polypeptide having a biological activity in the body of a mammal. The shaped mass is formed by compression of a precursor material comprising the drug wherein an amount of biologically active drug in the mass is a preserved above a minimum level. Drugs which may be incorporated into the shaped mass may include one or more glucose regulating proteins such as insulin, incretins; and immunoglobulins such as TNF-inhibiting antibodies or interleukin neutralizing antibodies. Embodiments of the shaped mass may be incorporated into a tissue penetrating member which is inserted into the intestinal wall allowing for the oral delivery of proteins and peptides which would otherwise be degraded in the intestinal tract.
US11026994B2	Syndecan-2 compositions and methods of use SDC2, compositions that comprise SDC2, vectors encoding SDC2 and compounds that modulate expression of SDC2 by cells are used for treatment of mammalian, e.g. human, cells to achieve immunomodulation or for other specific therapeutic interventions. Cells are treated by combining the cells with SDC2, treating the cells with an antibody or fragment thereof that binds SDC2 or modulating expression or activity of SDC2 by the cells. Cells or tissue are derived from treated cells for therapeutic uses based on their immunomodulatory or other therapeutic properties.
US11026992B2	Compositions and methods for preventing and reducing inflammation and treating disorders associated with inflammation The present invention relates to compositions and methods for preventing and reducing inflammation and preventing and treating diseases and disorders associated with inflammation. It has been shown that CRADD plays a pivotal role in maintaining the integrity of endothelial monolayers. The recombinant cell-penetrating CRADD protein (CP-CRADD)-based compositions and methods described herein provide for the development of a novel treatment for inflammatory vascular disorders including cardiovascular, cerebrovascular, respiratory, gastrointestinal, and renal systems.
US11026990B2	PUM 1 protein as target for virus inhibition Disclosed is a method for prophylaxis or treatment of infection of a virus, or for modulating innate immunity, in a subject comprising administering to the subject a therapeutically effective amount of a PUM1 inhibitor. A pharmaceutical composition comprising the PUM1 inhibitor is also disclosed.
US11026989B2	Composition for treating erectile dysfunction by Orchis anatolica extract A composition for treating erectile dysfunction in a male mammal comprising an Orchis anatolica root bulb extract. A method of treating erectile dysfunction in a mammal comprises administering a therapeutically effective amount of Orchis anatolica root bulbs alcohol extract in a male mammal.
US11026988B2	Traditional Chinese medicine composition and use thereof The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-β 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.
US11026987B2	Composition for remedying female climacteric syndrome symptoms The present disclosure relates to a composition for preventing, treating or remedying female climacteric syndrome symptoms, which contains an extract of Pueraria thomsonii flower or bud. The composition according to the present disclosure shows quick effects for preventing, remedying and/or treating female climacteric syndrome symptoms, particularly facial flushing and/or osteoporosis, and thus can be utilized for the hormone replacement therapy (HRT) used for preventing or remedying climacteric syndrome symptoms.
US11026986B2	Beetroot-containing composition An enhanced food composition in the form of a soup, sauce or condiment is described, the enhanced food composition comprising a nitrate-containing vegetable, such as beetroot, effectively mixed with a salt content at a specified ratio. The enhanced food composition has the effect to prevent an increase in blood pressure while masking the bad taste of the nitrate-containing vegetable.
US11026984B2	Use of isothiocyanate derivatives as modulators of peripheral and neuropathic pain The present invention relates to the use of glucomoringin (GMG) and of the corresponding isothiocyanate derivative glucomoringin des-thioglucoside (GMG-ITC) as modulators of peripheral pain with specific reference to that linked with diabetic peripheral neuropathy and chemotherapy-induced neuropathy.
US11026981B2	LDL-cholesterol-lowering cell extract and food supplement The present invention relates to a low-density lipoprotein (LDL)-cholesterol-lowering preparation, in particular to a bacterial cell extract for use as a medicament for lowering of the blood plasma LDL-cholesterol level, wherein the extract is obtained by extraction for between 10 minutes and 48 hours at between 8° C. and 37° C., while mixing the cells with the mixture, and wherein the ldl-cholesterol-lowering cell extract and food supplementldl-cholesterol-lowering cell extract and food supplement Rhodospirillum rubrum cells are extracted with the mixture in a volume ratio of between 10:1 and 1:10 of petroleum ether with a boiling point of between 60° C. and 80° C. and methanol comprising sodium chloride. More specifically, the present invention relates to a petroleum ether extract of Rhodospirillum rubrum obtainable by extraction of Rhodospirillum rubrum cells with a mixture of petroleum ether with a boiling point of between 60° C. and 80° C. and methanol comprising sodium chloride. The invention also relates to the petroleum ether extract of Rhodospirillum rubrum of the invention, for use in a method for the lowering of LDL-cholesterol in blood plasma of a subject. The invention further relates to a pharmaceutical preparation, a food supplement containing said preparation, a foodstuff containing said food supplement, and to a method for their preparation.
US11026974B2	Restimulation of cryopreserved tumor infiltrating lymphocytes The present disclosure provides methods for re-stimulating TIL populations that lead to improved phenotype and increased metabolic health of the TILs and provides methods of assaying for TIL populations to determine suitability for more efficacious infusion after re-stimulation.
US11026970B2	Methods and treatment of trauma adverse events with oxygen reduced blood Methods for the reversal of hemorrhagic shock or hemorrhagic trauma. Methods for restoring mean arterial pressure to a normal range and reducing trauma adverse risks in a patient through the administration of oxygen reduced blood compositions.
US11026968B2	Anticoagulation fluid comprising citrate and phosphate The present invention concerns an anticoagulation fluid comprising 10-40 mM citrate and 0.1-4 mM phosphate. The anticoagulation fluid is to be used for regional citrate anticoagulation in an extracorporeal blood circuit. The anticoagulation fluid may be combined with at least one treatment fluid in a dialysis treatment, and it may be included in a system for regional citrate anticoagulation in an extracorporeal blood circuit.
US11026967B2	Composition for suppressing or preventing abnormality in intestinal environment This application provides a composition comprising hydrogen gas or dissolved hydrogen as an active ingredient for suppressing or preventing abnormality in the intestinal environment of a subject, wherein the abnormality is selected from the group consisting of bacterial translocation and bacterial species composition abnormality of intestinal flora.
US11026966B2	Animal feed products containing percarbonate and methods of feeding same Methods of feeding livestock animals involve feeding the livestock animals a milk replacer comprising percarbonate. The milk replacer has a pH of about 5.8 and the concentration of percarbonate is effective to reduce bacterial growth within the milk replacer product. The milk replacer can also include at least one added organic acid.
US11026965B2	Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto Disclosed herein are cyclodextrin molecules covalently modified to store and release nitric oxide, as well as methods of making and uses thereof. The covalently modified cyclodextrin molecules may be tailored, in several embodiments, to release nitric oxide in a controlled manner and are useful for reduction and/or eradication of bacteria and for the treatment of disease.
US11026964B2	Delivery of RNA to different cell types RNA encoding an immunogen is co-delivered to non-immune cells at the site of delivery and also to immune cells which infiltrate the site of delivery. The responses of these two cell types to the same delivered RNA lead to two different effects, which interact to produce a strong immune response against the immunogen. The non-immune cells translate the RNA and express the immunogen. Infiltrating immune cells respond to the RNA by expressing type I interferons and pro-inflammatory cytokines which produce a local adjuvant effect which acts on the immunogen-expressing non-immune cells to upregulate major histocompatibility complex expression, thereby increasing presentation of the translated protein to T cells. The effects on the immune and non-immune cells can be achieved by a single delivery of a single RNA e.g. by a single injection.
US11026963B2	Senolytic compositions and uses thereof Provided herein are senolytic agents for selectively killing senescent cells that are associated with numerous pathologies and diseases, including age-related pathologies and diseases. As disclosed herein, senescent cell-associated diseases and disorders may be treated or prevented by administering at least one senolytic agent or pharmaceutical compositions thereof. The senescent cell-associated diseases or disorders treated or prevented by the methods described herein include, but are not limited to, cardiovascular diseases or disorders, cardiovascular diseases and disorders associated with arteriosclerosis, such as atherosclerosis, idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), osteoarthritis, inflammatory diseases or disorders, autoimmune diseases or disorders, pulmonary diseases or disorders, neurological diseases or disorders, dermatological diseases or disorders, chemotherapeutic side effects, radiotherapy side effects, metastasis and metabolic diseases.
US11026961B2	Use of biosurfactant An object is to provide a novel means for ameliorating mastitis or improving milk production. An ameliorating or therapeutic agent for mastitis that contains a biosurfactant, or a milk production promoting agent that contains a biosurfactant, is provided.
US11026959B2	Synthetic composition and method for treating irritable bowel syndrome The application relates to a method for treating a patient with irritable bowel syndrome (IBS), the method comprising administering to the patient a mixture comprising 2′-fucosyllactose (2′-FL) and lacto-N-neotetraose (LNnT).
US11026955B2	Synthetic bile acid compositions and methods Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
US11026954B2	3-beta-hydroxy-5-alpha-pregnan-20-one for use in medical treatment The present invention provides the steroid compound 3beta-hydroxy-5alpha-pregnan-20-one for use in treatment of Tourette's syndrome, obsessive compulsive disorder and/or gambling disorder, as well as methods for treating said disorders and pharmaceutical compositions for use in treatment of said disorders.
US11026950B2	Methods and compositions for treating mesothelioma and small lung cancer that express midkine Embodiments provided herein relate to methods and compositions for treating mesothelioma and/or a small cell lung cancer that express midkine.
US11026949B2	Combination therapy for treating cancer The present disclosure relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents (such as tyrosine kinase inhibitors or VEGF/VEGFR inhibitors), particularly anticancer agents such as sunitinib, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
US11026942B2	Agent for preventing and/or treating Alzheimer's disease The present invention provides a prophylactic or therapeutic agent for Alzheimer's disease (AD) containing a combination of two or more compounds selected from the group consisting of compounds shown by compound Nos. 1 to 130. Since these compounds are existing drugs that have already been confirmed actually for safety and pharmacokinetics in human, they can be a means for a pre-emptive treatment of people at risk of AD and in a stage before developing mild cognitive impairment (MCI).
US11026941B2	Concentrated, inhalable ciprofloxacin formulation A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
US11026940B2	Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same The invention provides compositions that increase the mobilization, homing, expansion, and/or differentiation of stem cells and methods of using the same for the treatment of mammals.
US11026939B2	High dosage valbenazine formulation and compositions, methods, and kits related thereto Solid pharmaceutical compositions with high drug loading are provided. A formulation useful for the solid pharmaceutical composition includes valbenazine, or a pharmaceutically acceptable salt thereof, silicified microcrystalline cellulose, isomalt, hydroxypropyl methylcellulose, partially pregelatinized maize starch, and magnesium stearate.
US11026935B2	Free base crystalline form of a complement component C5a receptor Provided herein is a free base crystalline form of a complement component 5a receptor having the formula of Compound 1 Also provided herein are pharmaceutical compositions and methods of treatment using the crystalline free base form of Compound 1 described herein.
US11026934B2	Topical retinoid compositions The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions. Further, the present application relates to method of using topical compositions for the treatment of skin disorders such as acne, rosacea, psoriasis etc.
US11026931B2	Methods for the administration of certain VMAT2 inhibitors Provided are methods of administering a vesicular monoamine transport 2 (VMAT2) inhibitor chosen from valbenazine, or a pharmaceutically acceptable salt and/or isotopic variant thereof, to a patient in need thereof.
US11026930B1	Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease Provided herein are methods and compositions for treating cancers, inflammatory diseases, rasopathies, and fibrotic disease involving aberrant Ras superfamily signaling through the binding of compounds to the GTP binding domain of Ras superfamily proteins including, in certain cases, K-Ras and mutants thereof, and a novel method for assaying such compositions.
US11026922B2	Compositions comprising melatonin and flavonoids for use in the treatment of tumours resistant to chemotherapy Compositions having at least one flavonoid of natural or synthetic origin in association with melatonin to increase the effectiveness of chemotherapeutic treatments used in human and veterinary medicine for the treatment of tumours are described. The compositions are in particular for the treatment of tumours resistant to the chemotherapeutic agents currently in use. The at least one flavonoid is selected from rutin, oxerutin, diosmin and hesperidin, preferably rutin.
US11026919B2	Formulation for soft anticholinergic analogs Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
US11026917B2	Antioxidative stress compositions, methods of preparing and uses thereof Antioxidative stress compositions, methods of using antioxidative stress composition and methods of preparing antioxidative stress composition compositions are described. The antioxidative stress compositions may be chemopreventive and/or immunomodulatory. Resveratrol, genistein, ellagic acid, curcumin and quercetin may be included in the antioxidative stress composition compositions individually or in any combination.
US11026916B2	Treatment for non-alcoholic fatty liver diseases Mixtures of vitamin E and polyunsaturated fatty acids (PUFAs) are provided as agents for the prevention, control and/or treatment of conditions associated with excessive fat accumulation in the liver which is not caused by alcohol abuse, including control and/or treatment of non-alcoholic steatosis in the liver—known as non-alcoholic fatty liver disease (NAFLD)—and/or non-alcoholic steatohepatitis (NASH) in a subject in need thereof.
US11026915B2	Preparation of a solution of cannabinoids for personal vaping The present invention comprises a method of manufacturing a cannabinoid solution including adding to a cannabis source comprising a cannabis distillate or a full spectrum alcohol extracted cannabis oil, adding a PEG, forming a mixture; and adding a PG to the mixture, forming the cannabinoid solution suitable for vaporization and inhalation to administer active cannabis compounds to a person in need thereof.
US11026911B2	Method of dietary treatment for genetic and epigenetic diseases and disorders Genetic and epigenetic diseases and disorders are treated with FDA approved dietary compositions in the form of dietary supplements and nutraceuticals. The diseases and disorders to be treated include Rett syndrome, trinucleotide repeat diseases such as Fragile X syndrome, memory impairment, chronic inflammation, pre-cancerous conditions which involve cancer stem cells, and post-cancerous conditions which involve cancer stem cells which have survived in spite of cancer treatment. Treatment options include prophylactic treatment which is initiated prior to the development of the symptoms of the disease or disorder.
US11026908B2	Extended release dosage forms of pregabalin The present invention relates to extended-release pharmaceutical compositions comprising pregabalin or a salt thereof, which are adapted to release the pregabalin active ingredient according to a dual release profile. The formulations comprise two components, the first (fast ER) providing extended-release of the active ingredient in a short controlled manner lasting from about 4 to about 6 hours, and the second (slow ER or maintenance) providing extended release of the active ingredient over a period of 24 hours. The proportion of each component in the formulation may be adjusted to achieve the desired AUC and therapeutic effect following oral administration to a subject. The invention further relates to methods of using the pharmaceutical compositions for treating conditions and disorders which are responsive to pregabalin treatment, such as neuropathic pain associated with diabetic peripheral neuropathy (DPN), post herpetic neuralgia (PHN), epilepsy, seizures and fibromyalgia.
US11026902B2	Topical composition and delivery system and its use The described invention provides a topical delivery system comprising a pharmaceutical composition for application directly to a skin of a subject in need thereof comprising (a) an effective therapeutic amount of an active therapeutic agent; (b) chemical drivers comprising an amino benzoate local anesthetic, ethoxydiglycol and methylsulfonylmethane (MSM) that in combination are effective to synergistically deliver the therapeutic agent; and (c) a depot component for keeping the pharmaceutical composition in the skin. Methods for delivering an active therapeutic agent into skin, for keeping it in the skin, for reducing systemic side effects attributable to entry of the active agent into the blood stream, and a method for treating a condition, disease or disorder of skin topically also are described in accordance with the embodiments of the described invention.
US11026898B2	Eutectic formulations of cyclobenzaprine hydrochloride The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol.
US11026888B1	Functional beverage compositions and methods of using and making same Functional beverage compositions in liquid form. The functional beverage compositions include water, lecithin, a punicic acid-containing oil, and a cannabinoid-containing oil. The punicic acid-containing oil and the cannabinoid-containing oil are stably suspended within the water. Methods of using the compositions include administering the compositions to reduce inflammation in a subject or treat an inflammation-related disease in a subject. Methods of making the compositions include suspending the punicic acid-containing oil and the cannabinoid-containing oil in a sub-volume of water and adding additional water to arrive at a final composition volume.
US11026886B2	Blend compositions for oral administration as a rapidly dissolving powder and/or suspension Disclosed is a dry powder oral formulation that includes an active pharmaceutical ingredient (API), a lecithin powder, a galactomannan, one or more sweetening agents, one or more flavoring agents and an organic acid in a pharmaceutically acceptable preparation. Also disclosed are an excipient composition in absence of an API and methods of making and using the formulations and compositions. Also disclosed is a chewable, swallowable, and/or orally disintegrating tablet comprising an active pharmaceutical ingredient (API), a lecithin powder, a galactomannan, one or more sweetening agents, one or more flavoring agents and an organic acid in a pharmaceutically acceptable preparation.
US11026885B2	Bioerodible silicon-based devices for delivery of therapeutic agents This invention discloses bioerodible devices, such as implants for delivering therapeutic agents, particularly large molecules such as proteins and antibodies, in a controlled manner. The devices comprise a porous silicon-based carrier material impregnated with the therapeutic agent. The device may be used in vitro or in vivo to deliver the therapeutic agent, preferably in a controlled fashion over an intended period of time such as over multiple days, weeks or months. The device may be used for treating or preventing conditions of a patient such as chronic diseases.
US11026881B2	Sedative laced toothpaste A toothpaste product that is laced with, or infused with, a sedative such as the active ingredients in cannabis. The act of brushing one's teeth using the present invention transfers the sedative into the bloodstream through contact with the gums, leading to a more restful sleep.
US11026880B2	Extract of passionflower seeds and cosmetic, pharmaceutical, dermatological and nutraceutical compositions comprising same The invention relates to a composition comprising an extract of passionflower seeds, and preferentially Passiflora edulis seeds. The composition is advantageously cosmetic, pharmaceutical, dermatological or nutraceutical. The subject matter of the invention is also a process for extracting an extract of passionflower seeds and preferentially Passiflora edulis seeds, and also the extract which can be obtained by means of said process. The invention also relates to such a composition or such an extract for use in the prevention or treatment of disorders or pathological conditions of the skin, of the mucous membranes or of the skin appendages, for use in the prevention or treatment of vascular disorders, for use for combating oxidative stress, or else for use in the prevention or treatment of adipose tissue modifications. Finally, the invention relates to a cosmetic care process for the skin, the skin appendages or the mucous membranes, with a view to improving, the condition thereof or the appearance thereof, consisting in administering such a composition or such an extract.
US11026871B2	Oral care compositions and methods of using the compositions An oral care composition is disclosed. The composition comprises zinc phosphate and a silicate compound comprising a metallic element that in cationic form is capable of reducing tooth enamel erosion. The zinc phosphate is added to the oral care composition as a preformed salt. Methods of administering the oral care compositions to subjects in need thereof are also disclosed.
US11026869B2	Process for producing small droplet emulsions at low pressure The present invention relates to novel process for making oil-in-water nanoemulsions. The oil phase contains oil selected from the group consisting of triglyceride oil and/or petrolatum and a C8 to C16 fatty acid just be added during preparation; and the aqueous phase contains specific N-acyl derivatives of carboxylic amino acid as primary emulsifier.
US11026865B2	Accelerated drying of soft capsules in a controlled environment A method of drying soft capsules including steps of: a) supplying a flow of air to said soft capsules at a velocity of the air across the soft capsules of from about 0.15 m/s to about 13 m/s; b) increasing, over time, a drying temperature to which said soft capsules are exposed while ensuring that the drying temperature remains below a melting temperature of a capsule shell of the soft capsules; c) exposing said soft capsules to an initial relative humidity of from about 49% RH to about 79% RH; d) decreasing the relative humidity to which the soft capsules are exposed as the capsules dry until an equilibrium relative humidity of the soft capsules reaches a desired relative humidity; and e) exposing the soft capsules from step d) to a temperature of from 20-25° C. Also disclosed is a drying system for carrying out the method.
US11026863B2	Connecting and container system A connecting system for providing a fluidic connection, preferably between containers, wherein the connecting system has at least two connecting arrangements configured to produce the fluidic connection, the connecting arrangements each having an opening region which is fluidically sealed in an initial state and is, in particular, film-shaped, brittle, fragile and/or unstable, and wherein the opening regions are each covered in sterile or sterilizable manner.

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