| Document | Document Title |
|---|---|
| US10988947B2 |
Deck construction device
A deck construction device for assisting with laying decking. The device as a body which has a handle and a substantially planar face from which at least two spacers extend. At least one screw hole is defined through the body, the at least two spacers are arranged to span a width of a decking plank. The length of a first spacer corresponds to the thickness of a decking plank; and the length of a second spacer extends beyond the thickness of the decking. |
| US10988944B2 |
Ceramic tile leveling bracket, pushing and clamping pliers and ceramic tile leveling and laying system
Disclosed are a ceramic tile leveling bracket, pushing and clamping pliers and a ceramic tile leveling and laying system. The ceramic tile leveling and laying system comprises: a ceramic tile leveling bracket (1), an insertion block (2) and pushing and clamping pliers (3), wherein the ceramic tile leveling bracket (1) is provided at the junction between two adjacent ceramic tiles (4), one end of the insertion block (2) is inserted into an insertion block through hole (16) of the ceramic tile leveling bracket (1), and the pushing and clamping pliers (3) push and clamp the insertion block (2) into the insertion block through hole (16), so that an insertion block bottom surface (21) is tangent to upper surfaces of the two ceramic tiles (4). The ceramic tile leveling and laying system is easy to operate, and helps to improve the laying efficiency and laying quality. |
| US10988942B2 |
Ceramic tile and method for manufacturing ceramic tiles
Ceramic tile having a ceramic base layer and a cover glaze layer including a printed pattern, where the surface of the ceramic tile has a relief having structural features corresponding to the printed pattern. The structural features are at least partly formed in the surface of the ceramic base layer and manifest themselves through the glaze layer to the upper surface of the tile. Additionally, a method which allows for the manufacturing of such ceramic tiles. |
| US10988939B2 |
Floor panel and method for manufacturing a floor panel
Floor panel with a substrate, including thermoplastic material, a decor provided thereon, and, on at least one pair of opposite edges, coupling parts realized at least partially from the substrate. The coupling parts allow to effect a mechanical locking between two of floor panels, where the substrate includes a rigid substrate layer of thermoplastic material, and a glass fiber layer is present in the floor panel. |
| US10988937B2 |
Non-slip ramp hardware
A method or system for constructing a non-slip ramp having at least two sloped ramp stringers and a starter wedge having a sloped side and an open side. A non-slip deck board is slid into the open side of the starter wedge and at least two tread plates, each providing spacing between two adjacent non-slip deck boards, each tread plate having a flat top section with a substantially L-shaped section attached perpendicular to the flat top section, with the bottom of the L fitting below one of the adjacent deck boards. The at least two tread plates are attached to the at least two sloped ramp stringers and an end-cap attached to a last non-slip deck board. |
| US10988936B2 |
Pergola louver tilt system
A pergola louver tilt system has a crossbeam with a track with a track groove. The system also has a post mounted on the crossbeam. A louver clip is pivotally mounted to post at a post joint. A louver is mounted to the louver clip. A pivot link is pivotally mounted to the louver clip. A stem is mounted to slide on the track groove. The pivot link is pivotally mounted to the stem at a stem connection pivot formed on the stem. A link connecting the stem to an adjacent stem, wherein the link includes a first link connection and a second link connection, wherein the first link connection connects to an adjacent stem, and wherein the second link connection connects to a subsequent stem. |
| US10988930B2 |
V-shaped tie reinforcement integrally provided with one-touch fixing device
The present invention relates to a V-shaped tie reinforcement for reinforcing a hoop reinforcement installed around a main reinforcement, wherein the V-shaped tie reinforcement is installed in order to prevent deformation, such as buckling, of the main reinforcement installed on a long member of an RC structure or an SRC structure, such as a column or a compression beam while preventing brittle fracturing of concrete. The present invention comprises: a V-shaped reinforcement composed of a bent part having a shape surrounding a main reinforcement at the center thereof and an anchor part open at both sides; and a fixing means composed of an upper tie reinforcement fixing brace fixedly installed at the V-shaped reinforcement and connected to the main reinforcement, and a rotation preventing brace fixedly installed at the bent part of the V-shaped reinforcement and preventing the V-shaped reinforcement connected to the main reinforcement from rotating upward and downward and right and left. |
| US10988929B2 |
Concrete component having a reinforcing element, method for producing same, method for bending a reinforcing bar of a reinforcing element, and bending device
A concrete component has a concrete matrix (49) and at least one non-metal reinforcing element (50), which can be shaped and at least one reinforcing part (29). The at least one reinforcing part (29) has a plurality of reinforcing threads (34) or reinforcing yarn arranged in a plastic matrix of a plastic (K). The plastic (K) is designed to be reversibly cross-linked. The cross-links can be released by heating the plastic (K) and reestablished by cooling the plastic back down. Thus, it is possible to produce and store a reinforcing element in completely hardened form as a standard element. In one application, the produced reinforcing element can be reshaped into the desired shape by releasing the cross-links in one or more locations, reshaping the reinforcing element, and then hardening the reinforcing element again by reestablishing the cross-links. |
| US10988925B2 |
Assembled light steel structure energy-saving composite wall
The assembled light steel structure energy-saving composite wall in the present invention comprises: a cement board and/or ceramic tile, a column, a support rod, a cross beam, a bottom plate, a diagonal brace and a diagonal draw steel bar. In the thickness direction of the composite wall, the horizontal side of each group of columns is outside the composite wall, a plurality of support rods and diagonal braces are installed between the four second vertical sides of the columns of the each opposite group of columns. In the width direction of the composite wall, a plurality of cross beams and diagonal draw steel bars are installed between the first vertical sides of the column of the adjacent groups of columns. On both sides of the thickness direction of the composite wall, the horizontal sides of the column of the two adjacent columns are provided with a cement board and/or a ceramic tile inserted by a strip fastener and a strip, and the space enclosed by the cement board and the ceramic tile, the cement board and the cement board or the ceramic tile and the ceramic tile is filled with the filler. The assembled light steel structure wall system is simple to assemble, convenient to transport, operate and maintain, energy-saving and heat-preserving, the wall installation and wall decoration is completed at one time. |
| US10988922B2 |
Storm avoiding buildings and structures
A building sheltering structure is configured to facilitate the shielding of at least one domicile or building into an underground foundation before an emergency environmental condition arises. The foundation includes a cover plate that translates horizontally to occlude the at least one domicile upon retraction into a secure cavity of the foundation by a lift assembly positioned at the bottom of the foundation cavity. Mounted atop the lift assembly, the at least one domicile can be fully retracted into the foundation cavity and completely shielded by the cover plate. The operation of the lift assembly is commanded and powered by a supply system. A processor of the supply system facilitates emergency warnings and panic transmissions to signal for help. Further, the supply system accommodates a plurality of solar panels mounted atop the at least one domicile to keep the system charged for the use in emergency. |
| US10988921B1 |
Method and devices enabling rapid construction of buildings
A method including placing on a surface a first beam having a first end with a first clevis component opposing a second clevis component. A second beam, including a second end having a third clevis component opposing a fourth clevis component, is placed adjacent the first end on the surface. The first clevis component is connected to the third clevis component. A lifter is connected to the first end and the second end, which are lifted simultaneously from the surface while rotating the first beam and the second beam about the connector until the second clevis component engages the fourth clevis component. Connection between the second clevis component and the fourth clevis component then may be completed. |
| US10988919B2 |
Shower floor assembly
A shower floor former assembly is provided which comprises a shower floor former having a non-circular waste-plate receiver and a drain waste plate which is dimensioned to be receivable in the waste-plate receiver. A centre point of the waste-plate receiver is offset from a centre point of the shower floor former, and the drain waste plate has a drainage aperture therethrough, a centre point of the drainage aperture being offset from a centre point of the drain waste plate. The drain waste plate is receivable in the waste-plate receiver in a first condition in which the centre point of the drainage aperture is offset relative to the centre point of the shower floor former. The drain waste plate is also receivable in the waste-plate receiver in a second condition in which the centre point of the drainage aperture is coincident with the centre point of the shower floor former. |
| US10988915B2 |
Hydraulic system of construction machinery
A hydraulic system of construction machinery includes: a boom cylinder divided; a first boom hydraulic line serving to supply a hydraulic oil to the boom cylinder during an ascending operation of a boom; a second boom hydraulic line serving to supply the hydraulic oil to the boom cylinder during a descending operation of the boom; a regeneration line serving so that the hydraulic oil discharged from the head side of the boom cylinder flows during the descending operation of the boom; a circulation line connected to the second boom hydraulic line; an accumulator connected to the regeneration line and serving to accumulate the hydraulic oil discharged from the boom cylinder; a boom regeneration valve including a first regeneration spool and a second regeneration spool; and a control unit serving to adjust opening areas of the first regeneration spool and the second regeneration spool during the descending operation of the boom. |
| US10988909B1 |
Additive manufacturing of support structures
In a general aspect, a method is presented for manufacturing support structures for offshore wind turbines. In some implementations, the method includes constructing a plurality of modular sections that assemble to define the support structure. One or more of the plurality of modular sections are configured to anchor to an underwater floor. At least one of the plurality of modular sections is constructed by operations that include forming a wall along a perimeter to bound a volume, filling the volume with a castable material, and hardening the castable material. In some instances, forming the wall includes depositing layers of printable material successively on top of each other. The method also includes joining the plurality of modular sections to assemble the support structure. |
| US10988908B2 |
Underground construction device
An underground construction device includes a hydraulic assembly having an internal combustion engine and a hydraulic pump driven by the internal combustion engine, a work device connected with the hydraulic assembly in a hydraulic circuit for introducing material to be pile-driven into the ground, a clamping apparatus connected with the work device for holding a material to be pile-driven, in clamped manner, which device has a hydraulic clamping cylinder, as well as a controller for opening and closing the hydraulic clamping apparatus. A further hydraulic pump for building up the clamping pressure of the clamping cylinder of the clamping apparatus is provided, which pump is operated by an electric motor. A method operates such an underground construction device. |
| US10988897B2 |
Cellulose materials and methods of making and using same
The present disclosure provides materials such as cellulose based materials and composite materials. Also provided herein are methods for making or using the materials. |
| US10988895B2 |
Laundry treating apparatus
A laundry treating apparatus may comprise a cabinet that defines an exterior design; a drum rotatably mounted in the cabinet and configured to accommodate laundry; a drive unit or motor configured to rotate the drum; a hot air supply unit or hot air blower configured to supply high-temperature air to the drum and in communication with the drum; a collection portion or liquid chamber provided to collect water condensed from the drum and in communication with the hot air supply unit; and a drainage pump configured to discharge the water collected in the collection portion outside the cabinet such that the laundry treating apparatus may sense whether the condensate collected in the collection portion is frozen and thaw the frozen condensate. A control method of the laundry treating apparatus may be provided to thaw and operate the laundry treating apparatus. |
| US10988887B2 |
Washing machine
A washing machine includes a water tub storing water, a rotary tub arranged in the water tub, a dissolving area in which a detergent is fed and dissolved, an FB feed-water pathway which includes a fine-bubble generation apparatus allowing generation of fine bubble water and along which water fed from a feed-water source is passed through the fine-bubble generation apparatus to be fed to the dissolving area as fine bubble water, an FB feed-water valve opening and closing the FB feed-water pathway, and a control apparatus controlling opening and closing of the FB feed-water valve. The detergent and the fine bubble water are controllably brought into contact with each other to dissolve the detergent, in a washing course in which the washing machine is operated and during a period when the detergent is dissolved in feed-water. |
| US10988881B2 |
Fabric cleaning appliance with performance enhancement selector
The laundry treating device has a user interface configured to receive a user selection of a preprogrammed wash cycle. A treating chemistry dispenser has multiple treating chemistry cups configured to dispense treating chemistry to the treating chamber during the selected washing cycle. A controller configured to activate dispensing from each of the treating chemistry cups at preprogrammed times during the wash cycle. A performance enhancement selector configured to receive a user selection such that activation of the performance enhancement selector causes the controller to dispense one of the treating chemistry cups at a different time than the preprogrammed time during the wash cycle. |
| US10988879B2 |
Sewing machine and holder member
The sewing machine includes an imaging unit, a conveyor portion, a processor, and a memory. The imaging unit has an image capture range, and is configured to capture an image of a holder member. The conveyor portion is configured to convey the holder member relative to the imaging unit in a first and a second direction. The processor performs processes. The processes include causing the imaging unit to capture the image of the holder member that has entered the image capture range. The processes include acquiring first image data that is data of a first image representing the image of the holder member. The processes include identifying a predetermined marker from the first image of the acquired first image data. The processes include determining whether an inclination angle of the holder member exceeds a predetermined value on the basis of a variable acquired on the basis of the identified marker. |
| US10988876B2 |
Cushion paper
The present invention provides a cushion member and a stage member provided with the cushion member, the cushion member including a non-woven fabric formed by binding or entangling metal fibers, wherein when the cushion member is compressed, the cushion member undergoes compressive deformation and the following compressive deformation ratio is 5% to 80%: Compressive deformation ratio=(T0−T1)/T0×100, T0: film thickness of cushion member before application of load, and T1: film thickness of cushion member after application and release of load. |
| US10988868B2 |
Textile structures comprising core spun yarns and associated methods for manufacture
Embodiments described herein generally relate to textile structures comprising core spun yarns, and associated methods for manufacturing. One example embodiment is a textile structure including one or more layers of warp yarns interwoven with one or more layers of weft yarns, wherein at least one of the one or more layers of warp yarns and one or more layers of weft yarns include one or more core spun yarns. |
| US10988866B2 |
Electromotively operating device for forming a leno selvedge for a loom and a projectile loom having such a device
The invention relates to an electromotively operating device (1) for forming a leno selvedge, comprising a rotor (10) having two thread-guide eyelets (14) arranged diagonally opposite each other in the rotor (10) for the leno threads, and a stator (30) accommodating the rotor (10). The rotor (10) has a magnetic disk (16), wherein the magnetic disk (16) has a plurality of alternately positive and negative magnetized segments (17), which are oriented in an axial direction of the rotor (10). |
| US10988865B2 |
Synthetic threads and materials and garments produced therewith
Disclosed is a thread combining multiple polymers. The thread consists of fibers of a first synthetic polymer of the Polyethylene terephthalate (PET) family and fibers of a second synthetic polymer of the Polyimide family, wherein the first fibers and the second fibers are combined together such that the resulting material, forming the thread, blocks photons with wavelengths falling within a first range of wavelengths and allows passage of photons with wavelengths falling within a second range of wavelengths. Photons whose wavelengths are within the second range of wavelengths, allowed to pass by the resulting material, may contribute to tanning of human skin. |
| US10988860B2 |
Method for manipulating crystal morphology to achieve stable fluidization
This disclosure provides an apparatus and method for improving the flowability of a powder by manipulating its crystal morphology. For example, a method and apparatus for achieving stable fluidization of a powder contained in a vessel. |
| US10988859B2 |
Nitrogen doped and vacancy dominated silicon ingot and thermally treated wafer formed therefrom having radially uniformly distributed oxygen precipitation density and size
Nitrogen-doped CZ silicon crystal ingots and wafers sliced therefrom are disclosed that provide for post epitaxial thermally treated wafers having oxygen precipitate density and size that are substantially uniformly distributed radially and exhibit the lack of a significant edge effect. Methods for producing such CZ silicon crystal ingots are also provided by controlling the pull rate from molten silicon, the temperature gradient and the nitrogen concentration. Methods for simulating the radial bulk micro defect size distribution, radial bulk micro defect density distribution and oxygen precipitation density distribution of post epitaxial thermally treated wafers sliced from nitrogen-doped CZ silicon crystals are also provided. |
| US10988857B2 |
SiC single crystal growth apparatus containing movable heat-insulating material and growth method of SiC single crystal using the same
A SiC single crystal growth apparatus of an embodiment includes a seed crystal installation part in which a seed crystal is installable at a position thereof which faces a raw material; a guide member which extends from a periphery of the seed crystal installation part toward the raw material and guides crystal growth performed inside the guide member; and a heat-insulating material which is movable along an extension direction of the guide member on the outside of the guide member. |
| US10988850B2 |
Electrodic support structure for coaxial electrolytic cells
An electrodic support structure for coaxial electrolytic cells suitable for operating in both monopolar and bipolar configuration is provided. The electrode support structure has a support plane made of an isolating material provided with a plurality of housing seats suitable for housing a plurality of electrodes arranged homothetically to each other, and a partition member made of insulating material, provided with a plurality of electrode positioning means, integral with or mechanically connected to the support plane and arranged orthogonally thereto. |
| US10988848B2 |
Electrolytic cell including elastic member
An electrolytic cell that prevents, or at least minimizes, damage to a membrane and reduces electrolytic voltage may include an elastic member attached to an electrolytic partition wall within an anode chamber and/or a cathode chamber. The elastic member comprises a spring retaining part and a bonding part that is bonded to the electrolytic partition wall, parallel first support parts extending from the bonding part away from the electrolytic partition wall, a second support part connecting the first support parts, and two parallel spring rows. Each spring row may include first flat spring-like bodies, which originate from the first support part and extend toward the opposite direction of the electrolytic partition wall, and second flat spring-like bodies, which originate from the second support part and extend toward the opposite direction of the electrolytic partition wall. |
| US10988843B2 |
System for determining cleaning process endpoint
A system for determining when a cleaning process has completed is disclosed. This system relies on an increase in the amount of gas in the processing chamber that occurs when the cleaning is complete. This increase in the amount of gas may be detected in several ways. In one embodiment, a downstream pendulum valve is used to maintain the pressure within the processing chamber at a predetermined value. An increase in the size of the opening in the pendulum valve is indicative of the amount of gas in the system. In another embodiment, a sensor may be used to monitor the pressure within the processing chamber, while the incoming and outgoing flow rates are held constant. An increase in the pressure is indicative of an increase in the amount of gas in the processing chamber. This increase in the amount of gas is used to terminate the cleaning process. |
| US10988840B2 |
Crystal oscillation probe structure and evaporation device
A crystal oscillation probe structure and an evaporation device are provided. The crystal oscillation probe structure includes a guide cover, a crystal oscillation probe and a mesh screen structure, the guide cover includes a chamber with a guide opening, the crystal oscillation probe is fixed in the chamber, the crystal oscillation probe includes at least one crystal oscillation sheet, the mesh screen structure includes a plurality of openings, and the mesh screen structure is located on a traveling path of a material traveling toward the at least one crystal oscillation sheet and disposed on a side of the at least one crystal oscillation sheet facing the guide opening. |
| US10988838B2 |
Color film and method of forming the same
The present invention provides a color film and a method of forming the same. In some embodiments, only one titanium target is used, and a flowrate of nitrogen gas, a working pressure, a sputtering power and a sputtering time are adjusted, so as to form single-layered titanium oxynitride color films having different colors and thicknesses. The color film has satisfactory adhesivity, a flat surface and metallic luster. |
| US10988832B2 |
Titanium-containing structure and titanium product
A titanium-containing structure made of a titanium material includes: a package made of a commercially pure titanium material; and a filler packed into the package, wherein an internal pressure of the package is 10 Pa or less, the pressure being an absolute pressure, and wherein the filler includes at least one selected from titanium sponge, titanium briquette, and titanium scrap, and the filler has the same type of a chemical composition of the commercially pure titanium material. This titanium-containing structure enables production of a titanium product by performing hot working and eliminating the conventional melting step and forging step. |
| US10988829B2 |
Method for producing nickel alloys with optimized strip weldability
The invention relates to methods for the manufacture of nickel alloys having optimized strip weldability (TIG without filler) from an alloy of the following composition (in wt %): C max. 0.05%, Co max. 2.5%, Ni the rest, especially >35-75.5%, Mn max. 1.0%, Si max. 0.5%, Mo >2 to 23%, P max. 0.2%, S max. 0.05%, N up to 0.2%, Cu ≤1.0%, Fe >0 to ≤7.0%, Ti >0 to <2.5%, Al >0 to 0.5%, Cr >14 to <25%, V max. 0.5%, W up to 3.5%, Mg up to 0.2%, Ca up to 0.02%, in that the alloy is smelted openly and cast as ingots, the ingots are subjected if necessary to at least one heat treatment, the ingots are then remelted at least one time by electroslag refining, the remelted ingot obtained in this way is subjected if necessary to at least one heat treatment, the ingot is subjected to at least one cold and/or hot deformation cycle, until strip material of predeterminable material thickness exists, the strip material is subdivided into strip sections of defined lengths/widths. |
| US10988825B2 |
Martensitic stainless steel sheet
A martensitic stainless steel has a chemical composition containing, by mass %, C: 0.030% or more and less than 0.20%, Si: 0.01% or more and 2.0% or less, Mn: 0.01% or more and 3.0% or less, P: 0.050% or less , S: 0.010% or less, Cr: 10.0% or more and 16.0% or less, Ni: 0.01% or more and 0.80% or less, Al: 0.001% or more and 0.50% or less, Zr: 0.005% or more and 0.50% or less, and N: 0.030% or more and less than 0.20%, with the balance consisting of Fe and inevitable impurities. |
| US10988822B2 |
Grain-oriented electrical steel sheet and method for manufacturing same
In a grain-oriented electrical steel sheet including: a steel substrate; a forsterite base film; and an insulating coating, critical damage shear stress τ between the forsterite base film and the steel substrate is 50 MPa or more and 200 MPa or less. Thus, a grain-oriented electrical steel sheet having excellent insulation property, stacking factor, and magnetic property is provided without coating damage even when magnetic domain refining treatment by thermal strain is performed. |
| US10988821B2 |
Wire rod having excellent cold forgeability and manufacturing method therefor
Disclosed are a wire rod and a manufacturing method therefor. The wire rod comprises in percentage by weight: 0.02 to 0.15% of C; 0.05 to 0.3% of Si; 0.5 to 1.2% of Mn; 0.3 to 0.9% of Cr; 0.02% or less of P; 0.02% or less of S; 0.01 to 0.05% of sol. Al; 0.01% or less of N; Fe as the remainder; and unavoidable impurities, wherein the wire rod satisfies following formulas 1 and 2, wherein, when the hardness of the wire rod measured in 1/2d position and in 1/4d position in the diameter direction of the wire rod is Hv,1/2d(Hv) and Hv,1/4d(Hv), respectively (here, d is the diameter of the wire). (Hv,1/2d+Hv,1/4d)/2≤150 [Formula 1] Hv,1/2d/Hv,1/4d≤1.2 [Formula 2] |
| US10988820B2 |
1500 MPa grade press hardening steel by medium thin slab casting and direct rolling and method for producing the same
A press hardening steel by a medium thin slab and having a tensile strength of 1500 MPa or more, includes following components by weight percent: C: 0.21%-0.25%, Si: 0.26%-0.30%, Mn: 1.0%-1.3%, P≤0.01%, S≤0.005%, Als: 0.015%-0.060%, Cr: 0.25%-0.30%, Ti: 0.026%-0.030% or Nb: 0.026%-0.030% or V: 0.026%-0.030% or a mixture of any two or more of the above in any proportion, B: 0.003%-0.004%, Mo: 0.17-0.19% and N≤0.005%. A method for producing the press hardening steel includes following steps: molten iron desulphurization; smelting and refining by an electric furnace or converter; continuous casting; descaling treatment before entering a soaking furnace; hating and soaking; high pressure water descaling before entering a rolling mill; hot rolling; cooling; coiling; austenitizing; die deforming and quenching. |
| US10988819B2 |
High-strength steel material and production method therefor
A high-strength steel material that has a chemical composition containing, by mass %, C: 0.30 to 1.0%, Si: 0.05 to 1.0%, Mn: 16.0 to 35.0%, P: 0.030% or less, S: 0.030% or less, Al: 0.003 to 0.06%, N: 0.1% or less, V: 0 to 3.0%, Ti: 0 to 1.5%, Nb: 0 to 1.5%, Cr: 0 to 5.0%, Mo: 0 to 3.0%, Cu: 0 to 1.0%, Ni: 0 to 1.0%, B: 0 to 0.02%, Zr: 0 to 0.5%, Ta: 0 to 0.5%, Ca: 0 to 0.005%, Mg: 0 to 0.005%, and the balance: Fe and impurities, and that satisfies [V+Ti+Nb>2.0], in which: a number density of carbides/carbo-nitrides having a circle-equivalent diameter of 5 to 30 nm precipitating in the steel is 50 to 700/μm2, and a number density of carbides/carbo-nitrides having a circle-equivalent diameter of more than 100 nm precipitating in the steel is less than 10/μm2; a yield stress is 758 MPa or more; and a KISSC value obtained in a DCB test is 33.7 MPa·m0.5 or more. |
| US10988817B2 |
Oxygen injection system for a direct reduction process
An oxygen injection system for a direct reduction process, including: a common circumferential gas injection header adapted to be coupled to an oxygen source and an enrichment natural gas source and adapted to deliver oxygen from the oxygen source and enrichment natural gas from the enrichment natural gas source to a reducing gas stream flowing through a conduit axially disposed within the common circumferential gas injection header through a plurality of circumferentially disposed ports to form a bustle gas stream; wherein the common circumferential gas injection header includes a circumferential oxygen injection header adapted to deliver the oxygen from the oxygen source to the reducing gas stream through the plurality of circumferentially disposed ports and a circumferential enrichment natural gas injection header adapted to deliver the enrichment natural gas from the enrichment natural gas source to the reducing gas stream through the plurality of circumferentially disposed ports. |
| US10988814B2 |
Siniperca chuatsi IL-6 gene and detection method of disease-resistant SNP marker thereof
The invention provides a Siniperca chuatsi IL-6 gene and a detection method for a disease-resistant SNP marker. A cDNA sequence of S. chuatsi IL-6 gene is cloned, as shown in SEQ ID NO: 1. AIL-6 gene gDNA sequence containing an intron of the S. chuatsi IL-6 gene is cloned, as shown in SEQ ID NO: 2. A primer for amplifying a disease-resistant SNP locus is designed according to IL-6 gDNA sequence, and S. chuatsi IL-6 gene is amplified to obtain an amplification product which is sequenced, and the SNPs loci relevant to virus disease-resistance are found out and the SNP locus is determined according to DNA peak profile. The IL-6 cDNA full-length sequence and IL-6 gDNA full-length sequence are cloned firstly. The SNP locus relevant to virus disease resistance of S. chuatsi IL-6 gene is detected, thereby providing a new method for breeding of S. chuatsi. |
| US10988808B2 |
Synthesizing barcoding sequences utilizing phase-shift blocks and uses thereof
Provided herein are compositions and methods for generating phase-shift barcode oligonucleotides for library construction for next-generation sequencing. In some cases, barcode oligonucleotides are attached to particles or beads. Also provided are methods and kits for using the phase-shift barcode oligonucleotides in sequencing assays. |
| US10988805B2 |
Methods related to DNA sequencing
In some aspects, the invention relates to a method for producing a barcoded DNA library, comprising: optionally fragmenting DNA to produce fragmented DNA; combining the DNA/fragments with control nucleotide sequences to produce a mixture of nucleic acids, each control nucleotide sequence comprising a variable nucleotide sequence, thereby barcoding the DNA/fragments; amplifying the mixture of nucleic acids to produce amplified nucleic acids; isolating a plurality of nucleic acids from the amplified nucleic acids; and rearranging the nucleic acids of the plurality, thereby producing the barcoded DNA library. |
| US10988804B2 |
Nucleic acid sequencing apparatus for monitoring status of a transplant recipient
The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant. |
| US10988788B2 |
Plants expressing cell wall degrading enzymes and expression vectors
Vectors for expression of proteins in plants are described. The proteins may be enzymes and the enzymes can be but are not limited to cell wall degrading enzymes. A number of plants designed to express specific cell wall degrading enzymes are provided. The plants may have industrial and/or agricultural applications. Methods and materials for making the expression vectors and for making the plants are provided. Processes for which the plants could be used in industrial and agricultural applications are also provided. |
| US10988782B2 |
Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| US10988777B2 |
Method for inducing CCR5Δ32 deletion by using CRISPR-Cas9 genome editing technique
The present invention relates to a new method for successfully inducing the mutation of cell chemokine receptor CCR5 gene into CCR5Δ32 deletion gene by using the CRISPR-Cas9 genome editing technique. CCR5 is an important co-receptor for entry of Human Immunodeficiency Virus (HIV) into human host cells. CCR5Δ32 deletion is a 32-bp deletion in CCR5 coding region, which results in change and premature termination in the sequence following the 185th amino acid. Biallelic homozygous deletion of CCR5Δ32 is naturally resistant to HIV infection, i.e., the people carrying this mutation can't be infected by HIV. The present invention uses both lentiviral packaging system and the CRISPR technique to induce CCR5Δ32 deletion. Due to the characteristics of a wide range of Lentivirus infection, the invention can be applied to cells such as bone marrow stem cells and CD4+ T cells and can be expected to be the therapeutic drug for HIV/AIDS infection or other diseases. |
| US10988776B2 |
Methods of modifying genes in eukaryotic cells
Methods of creating mutations in genomic exons by inserting introns into the genomic exons via homologous recombination. Also, methods are provided for introducing modifications into genomic exons by inserting introns into the genomic exons via homologous recombination such that a mature mRNA transcript produced from a genomic region of the genome comprising the genomic exon does not contain the modification are provided. The methods provide for a rapid method for introducing mutations and/or modifications of any type into a mammalian cell genome. |
| US10988774B2 |
System for site-specific modification of ALS gene using CRISPR-Cas9 system for production of herbicide-resistant rice and use of same
The present invention discloses a system for site-specific modification of ALS gene by a CRISPR-Cas9 system to produce herbicide-resistant rice, and uses thereof. The system for site-specific modification in a plant genome of the present invention comprises a vector for site-specific modification in a plant genome and a donor DNA; wherein the vector for site-specific modification in a plant genome comprises a Cas9 protein expression cassette, gRNA expression cassettes and a donor DNA; the gRNA expression cassettes encode two gRNAs targeting two target sites of a target DNA of a plant of interest, respectively; the target DNA has a fragment to be site-specifically modified which is positioned between the two target site. |
| US10988772B2 |
Low glucosinolate pennycress meal and methods of making
Pennycress (Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided. |
| US10988764B2 |
Compositions and methods for regulating gene expression via RNA interference
The present disclosure provides compositions and methods for regulating gene expression via RNA-mediated silencing. The present disclosure also provides compositions and methods to optimize the processing of a dsRNA molecule into small RNA duplexes. The present disclosure further provides compositions and methods to improve the efficiency of a dsRNA molecule in producing desired small RNAs and promoting the silencing of a gene of interest. |
| US10988758B2 |
Magnetic nanoparticles for nucleic acid purification
The present invention relates to monodisperse silanized ferrimagnetic iron oxide particles, a method for producing the same and a method for independent generic binding of nucleic acid molecules to the particles. |
| US10988756B2 |
Microchip
A microchip comprises a DNA analysis part configured to analyze DNA, which comprises at least a cell lysis chamber for cell lysis and a DNA extraction chamber which is connected to the cell lysis chamber and configured to extract DNA from lysed cells, and a DNA preservation part which is connected to the DNA analysis part via a flow path and configured to preserve a partial portion of a DNA sample. |
| US10988752B2 |
3-methylcrotonic acid decarboxylase (MDC) variants
Described are 3-methylcrotonic acid decarboxylase (MDC) variants showing an improved activity in converting 3-methylcrotonic acid into isobutene as well as methods for the production of isobutene using such enzyme variants. |
| US10988749B2 |
Beta-lactamase variants
The present invention relates to an isolated polypeptide having beta-lactamase activity and nucleic acid sequences encoding the polypeptide. The isolated polypeptide of the invention is a VIM-2 variant with improved properties such as improved protease stability. |
| US10988748B2 |
Compositions and methods for treating celiac sprue disease
Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO:1, are provided, wherein (a) the polypeptide degrades a PFQPQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456. |
| US10988747B2 |
Detergent composition comprising GH9 endoglucanase variants I
The present disclosure relates to a detergent composition comprising endoglucanase variants and methods for use of said compositions. |
| US10988743B2 |
Coryneform bacterial transformant and method for producing 4-aminobenzoic acid or salt thereof using same
Provided is a microorganism that is capable of efficiently producing para-aminobenzoic acid (4-ABA) or a salt thereof, using saccharides as raw materials, and a method for efficiently producing 4-ABA or a salt thereof by using this microorganism.A transformant obtained by introducing, into a coryneform bacterium, a gene that encodes 4-amino-4-deoxychorismate lyase, a gene that encodes a para-aminobenzoate synthase component I, and a gene that encodes a para-aminobenzoate synthase component II, is capable of efficiently producing 4-ABA or a salt thereof from saccharides. |
| US10988739B2 |
Ketoreductase polypeptides
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe. |
| US10988736B2 |
Method of isolating mesenchymal stem cells from the amniotic membrane of the umbilical cord, a mesenchymal stem cell population isolated from the amniotic membrane of the umbilical cord and a cell culture medium for isolating mesenchymal stem cells from the amniotic membrane of the umbilical cord
The present invention relates to a method of isolating a mesenchymal stem cell population from the amniotic membrane of the umbilical cord, the method comprising cultivating umbilical cord tissue in a culture medium comprising DMEM (Dulbecco's modified eagle medium), F12 (Ham's F12 Medium), M171 (Medium 171) and FBS (Fetal Bovine Serum). The invention also relates to a mesenchymal stem population isolated from the amniotic membrane of the umbilical cord, wherein at least about 90% or more cells of the stem cell population express each of the following markers: CD73, CD90 and CD105 and lack expression of the following markers: CD34, CD45 and HLA-DR. The invention also relates to a pharmaceutical composition of this mesenchymal stem population. |
| US10988734B2 |
Methods for preparing therapeutically active cells using microfluidics
The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses. |
| US10988729B2 |
Induction of protective immunity against antigens
Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest. |
| US10988724B2 |
Three-dimensional bioreactor for cell expansion and related applications
The present disclosure relates to the design, fabrication, and applications of a three-dimensional (3D) bioreactor for cell expansion and cell secreted substance production. The bioreactor is composed of non-random interconnected voids providing a continuous three-dimensional surface area for cell adherence and growth. |
| US10988720B1 |
Peel plate assembly
Peel plates and plate assemblies are shown and described. In one embodiment, a peel plate assembly includes a semi-rigid plate, a removable cover seal, and an adhesive to provide a moisture vapor barrier. In particular embodiments, the moisture vapor barrier provides less than about one pound peel adhesion and a stiffness for reapplication without wrinkling. The result is a peel plate, assembly, and method for the enumerating a microorganism, when present, in a sample. |
| US10988719B2 |
Method for producing beers stored, offered, served or consumed in UV-VIS-transmittant bottles with reduced sensitivity, in particular no sensitivity, to skunky thiol flavor degradation upon exposure to sunlight or other sources of UV and/or VIS light, and beers stored, offered, served or consumed in UV-VIS-transmittant bottles with reduced sensitivity, in particular no sensitivity, to skunky thiol flavor degradation upon exposure to sunlight or other sources of UV and/or VIS light
The invention relates to a method for preparing a brewed beverage, in particular a light-coloured lager or ale beer, (to be) bottled, (to be) stored, (to be) offered, (to be) served or (to be) consumed in a UV-VIS-transmittant bottle, comprising the addition of hulupones and/or reduced hulupones during the brewing process in an effective amount to obtain a brewed beverage, wherein the fraction of hulupones and/or reduced hulupones in the total of isohumulones and (reduced) hulupones is at least 25 mol %, The invention further relates to a brewed beverage, in particular a light-coloured lager beer or ale beer, bottled, (to be) stored, (to be) offered, (to be) served or (to be) consumed in a UV-VIS-transmittant bottle, comprising (reduced) hulupones and wherein the frac-tion of hulupones and/or reduced hulupones in the total of isohumulones and (reduced) hulupones is at least 25 mol %. |
| US10988717B2 |
Laundry stain and soil pretreatment devices
A laundry stain and soil pretreatment sheet including a water soluble or water dispersible carrier layer, preferably polyvinyl alcohol, a removable separator layer, and a layer of cleaning agent composition therebetween. The separator layer is removed, the composition layer is adhered to a stain on clothing, and the clothing is laundered. The carrier layer dissolves or disperses during the laundering. The separator layer can be water soluble or water dispersible. Depressions can be provided in the carrier layer to hold the layer of cleaning agent composition. Without the separator layer, a sheet of the carrier layer can be folded over to hold the cleaning agent composition. |
| US10988716B2 |
Polysaccharide derivatives as optical brightening agents
Provided herein are polysaccharide derivatives substituted (a) at a degree of substitution (DS1) of at least 0.05 by a fluorescent group (FG) having a mono or polycyclic ring system including at least one heteroatom selected from N, O and S and conjugated double bonds, and having an absorption band in the UV region of light and an emission band in the visible region of light, and bonded via a first linker to any one of the native functional groups of the polysaccharide repeating units; and (b) at a degree of substitution (DS2) of at least 0.05 by a charged group (CG) bonded via a second linker to any one of the native functional groups of the polysaccharide repeating units. |
| US10988712B1 |
Water mineral cleaning solutions and related methods
Implementations of cleaning compositions may include at least one of sodium lauryl sulfate, hydrochloric acid, muriatic acid, hydrobromic acid, and hydroiodic acid. Such implementations may also include benzalkonium chloride and either coco betaine or cocamidopropyl betaine. Such implementations may also include iodized salt, sodium sulfonate, and potassium nitrate. |
| US10988708B2 |
Systems and methods for fatty acid alkyl ester production with recycling
Provided are industrial processes for producing a fatty acid alkyl ester from a natural oil feedstock or a mixed lipid feedstock, wherein the natural oil feedstock comprises a free (un-esterified) organic acid such as a free fatty acid, comprising: producing fatty acid alkyl esters using an alcoholysis reaction such as a vapor phase alcoholysis reaction or a supercritical alcoholysis reaction, wherein the alcoholysis reaction takes place under conditions comprising: mixing the natural oil feedstock and/or mixed lipid feedstock and alcohol into an alcoholysis reactor or equivalent, and then depressurizing, and then recovering the fatty acid alkyl esters from the alcoholysis reactor or equivalent by distillation in a distillation column, leaving a still pitch or distillation bottoms in the distillation column or equivalent, wherein the fatty acid alkyl esters can be removed from the alcoholysis reactor or equivalent with or without cooling of the reaction mixture prior to depressurization. |
| US10988706B2 |
Musk compositions and methods of use thereof
A fragrance composition comprising one or more musk or fragrance accords for use in reducing or inhibiting a subject's physiological reaction to stress. The composition can be incorporated into consumer products. |
| US10988703B2 |
Metal working fluid
A metal working fluid having increased resistance to bacterial growth. The metal working fluid includes a cross-linked polymeric ester emulsifier; and an amine represented by the formula (H2N)a-Q-(NH2)b, where a and b are each integers, and Q is at least one carbon atom. Q may also be represented by X—Y—Z, where a+b≥2; X is a cyclic ring system including 3 to 24 carbon atoms; and Y and Z are groups that include at least one carbon atom directly attached to the cyclic ring system. The metal working fluid may also include a biocide, and may also include an amide that is formed by reacting the amine with a carboxylic acid. |
| US10988699B2 |
Plasma gasification reactor and method
The invention is related to a reactor (1) comprising at least one temperature unit (20) which provides high temperature, at least one waste inlet (11) from which the fuel and/or wastes are fed to the reactor (1), at least one reactant inlet (13 and/or 14 and/or 17), at least one melt outlet (15) which provides exiting of the melts formed by inorganic substances coming from the fuel and/or wastes via heat, at least one high temperature region (12) where endothermic reactions occur and a gas outlet (16) which provides that the fuel and/or wastes entering to the reactor (1) are directed to the high temperature region (12) such that the gasification does not start before they enter to this region (12) and therefore, where the gases leaving the reactor (1) as a result of the reaction exit from the reactor (1) by passing through the high temperature region (12) and which has a different openness from the waste inlet (11); having a high temperature region (12) positioned between the waste inlet (11) and gas outlet (16), and body (10) which has a form providing that the wastes pass through the high temperature region (12) such that the gasification does not start before the fuel and/or wastes entering to the reactor (1) enter to the high temperature region (12) and therefore, that the gases having at least 1200° C. temperature exit from the reactor (1) and to the working method (100) of this reactor (1). |
| US10988694B2 |
Flame retardant resin composition, and formed part and wiring material each using the same
A flame retardant resin composition containing from 30 to 300 parts by mass of a boehmite and an aluminum hydroxide as a total with respect to 100 parts by mass of the resin, wherein a content ratio of the boehmite and the aluminum hydroxide [content of boehmite:content of aluminum hydroxide] is from 85:15 to 15:85; a formed part; and a wiring material each using the same. |
| US10988692B2 |
Liquid crystal medium and liquid crystal device
The invention relates to a medium comprising at least 60% of one or more compounds of formula I wherein R11, R12, MG11, MG12 and Sp1 have the meaning given herein below, to the use of such media in liquid crystal devices, in particular in flexoelectric liquid crystal devices, and to a flexoelectric liquid crystal device comprising a liquid crystal medium according to the present invention. |
| US10988691B2 |
Liquid-crystal medium
The present invention relates to dielectrically positive liquid-crystalline media comprising one or more compounds of the formula I and II in which the parameters have the respective meanings indicated in claim 1, and to liquid-crystal displays, especially active-matrix displays and in particular displays of the vertically aligned mode, containing these media. |
| US10988689B2 |
Corrosion inhibitor compositions and methods of using same
Disclosed herein are sulfur-functional tall oil compositions, referred to herein as S-TO compositions. The S-TO is a sulfur-functional tall oil fatty amide composition, or sulfur-functional tall oil phosphate ester composition. Also disclosed herein are S-TO concentrates, which are stable and do not degrade to form H2S under standard storage conditions for a period of 1 day to 5 years. Also disclosed herein are treated water sources and treated metal containments including one or more S-TO compositions. The S-TO compositions inhibit corrosion of a metal containments contacted with one or more water sources, wherein the one or more water sources comprise one or more corrodents. The S-TO compositions are as effective or more effective at inhibiting corrosion than conventional sulfur-based corrosion inhibitors when compared on a weight basis. |
| US10988684B2 |
Electrochromic compound, electrochromic composition, electrochromic element, and electrochromic dimming element
To provide an electrochromic compound represented by the following general formula (1) where X1 and X2 are each independently a carbon atom or a nitrogen atom, R1, R2 and R3 are each independently a halogen atom, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted alkoxy group, x is an integer selected from 0 through 3, y and z are each independently an integer selected from 0 through 4, and at least one of L1 and L2 is a monovalent functional group bonded to a nitrogen atom of a pyridinium ring directly, or via a divalent substituent. |
| US10988683B2 |
Proppant treatments for mitigating erosion of equipment in subterranean fracturing operations
Systems and methods for treating proppant to mitigate erosion of equipment used in certain subterranean fracturing operations are provided. In some embodiments, the methods comprise: conveying a plurality of coated proppant particulates into a blender, wherein the coated proppant particulates comprise at least a partial coating of DFR and/or a hydratable polymer; blending the plurality of coated proppant particulates with an aqueous base fluid in the blender to form a treatment fluid; and introducing the treatment fluid from the blender into at least a portion of a subterranean formation. |
| US10988681B2 |
Nanocomposite coated proppants and methods of making and use thereof
Methods for producing proppants with a nanocomposite proppant coating are provided. The methods include coating the proppant particles with a nano-reinforcing agent, a surface modifier, and a resin to produce proppants with nanocomposite proppant coating. Additionally, a proppant comprising a proppant particle and a nanocomposite proppant coating is provided. The nanocomposite proppant coating includes a nano-reinforcing agent, a surface modifier, and a resin. The nanocomposite proppant coating coats the proppant particle. Additionally, a method for increasing a rate of hydrocarbon production from a subsurface formation through the use of the proppants is provided. |
| US10988678B2 |
Well treatment operations using diverting system
The flow of a fluid may be diverted from a high permeability zone to a low permeability portion of a subterranean formation by use of particulates comprising dicarboxylic acid, ester or an anhydride of the formula: or an anhydride thereof, wherein R1 is —COO—(R5O)y—R4 or —H; R2 and R3 are selected from the group consisting of —H and —COO—(R5O)y—R4, provided both R2 and R3 are —COO—(R5O)y—R4 when R1 is —H and further provided only one of R2 or R3 is —COO—(R5O)y—R4 when R1 is —COO—(R5O)y—R4, R4 is —H or a C1-C6 alkyl group, R5 is a C1-C6 alkylene group, and each y is 0 to 5. The dicarboxylic acid, ester or anhydride may further be admixed with an aliphatic polyester having the general formula of repeating units: where n is an integer between 75 and 10,000 and R is selected from the group consisting of hydrogen, alkyl, aryl, alkylaryl, acetyl, heteroatoms, and mixtures; thereof. |
| US10988676B1 |
Methods of making and using a high temperature wellbore servicing fluid
A method of servicing a wellbore penetrating a subterranean formation, comprising: placing a wellbore servicing fluid (WSF) into the wellbore, wherein the WSF comprises a first polymer, a second polymer, and water, wherein the first polymer is formed by polymerizing monomers comprising three of 2-Acrylamido-2-methyl propane sulfonic acid (AMPS), N,N-dimethylacrylamide (NNDMA), acrylamide, N-vinylacetamide, allyloxy-2-hydroxy propane sulfonic acid (AHPS), acrylic acid (AA), 2-acrylamido-2-tert.-butyl sulfonic acid (ATBS), or N,N-Dimethylaniline, and the second polymer is formed by polymerizing monomers and/or crosslinkers comprising AMPS, vinylpyrrolidinone, pentaerythritol allyl ether, and methylenebisacrylamide, wherein in the vinylpyrrolidinone, the 2-Pyrrolidone group can be substituted by a heterocyclic group, comprising one or more Z membered rings with Y heteroatoms, wherein Z is equal to or greater than three, and wherein Y is equal to or greater than one. |
| US10988675B2 |
Method to hydraulically fracture a well
A method may include: determining a total dissolved solids (TDS) concentration of a water source; correlating the TDS concentration to an ion concentration; and selecting at least one friction reducing polymer for a hydraulic fracturing operation based at least in part on the ion concentration. |
| US10988665B2 |
Permeable and decomposable plug forming rapidly dehydrating fluid (RDF)
A rapidly dehydrating fluid (RDF) composition that forms a permeable and decomposable plug and methods of lost circulation control and manufacture of the RDF composition. The RDF composition may include a carrier fluid such as water, a cellulosic microfiber viscosifier, date tree seed particles, and fibers formed from date tree waste such as date tree trunks. The RDF composition may mitigate or prevent lost circulation by forming a decomposable plug in a fracture of the lost circulation zone and may also enable the production of hydrocarbons from the zone without removal of the plug. |
| US10988661B2 |
Mitigation of annular pressure build-up using treatment fluids comprising calcium aluminate cement
Methods, compositions, and systems for treating a well are included. A method comprises introducing a treatment fluid comprising a calcium aluminate cement, a cement set retarder, and water into a wellbore. The method further comprises removing a portion of the treatment fluid from the wellbore. |
| US10988659B2 |
Layered double hydroxides for oil-based drilling fluids
A method of preparing and a composition of an oil-based drilling fluid. An oil-based drilling fluid includes a base oil continuous phase, in which the base oil continuous phase includes a base oil, an aqueous dispersed phase, and at least one rheology modifier comprising a modified magnesium/aluminum carbonate layered-double hydroxide (Mg/Al—CO3 LDH) compound. |
| US10988655B2 |
Composition for thermal storage and heat transfer applications
In accordance with the present subject matter there is provided a composition including at least one nanoparticle, at least one alkali metal salt and a metal salt having water of crystallization. The subject matter also relates to a method for preparation of the composition. |
| US10988652B2 |
Method for using a mixture of fluorinated hydrocarbons as a refrigerant, and a refrigeration unit using the mixture as a refrigerant
The present invention provides a method for using, as an alternative refrigerant for R404A that is currently widely used, a refrigerant that has, for example, a non-flammability similar to that of R404A, a refrigerating capacity that can replace that of R404A, a COP equal or superior to that of R404A, and a lower GWP than that of R404A, as a refrigerant for a cooling system; as well as a refrigeration unit using the refrigerant. The method uses a mixture of fluorinated hydrocarbons as a refrigerant, (1) the mixture comprising difluoromethane (R32), pentafluoroethane (R125) and 1,1,1,2-tetrafluoroethane (R134a) in amounts such that the sum of the concentrations thereof is 99.5 wt % or more; (2) the composition ratio of the fluorinated hydrocarbons contained in the mixture falling within a triangle having, as vertices, the following three points in a ternary composition diagram in which the sum of the concentrations of R32, R125, and R134a is 100 wt %, point A (R32/R125/R134a=37.3/17.0/45.7 wt %), point F (R32/R125/R134a=30.7/10.9/58.4 wt %), and point G (R32/R125/R134a=29.4/14.1/56.5 wt %); and (3) the mixture being used as a refrigerant in a cooling system comprising a heat exchanger in which a flow of the refrigerant and a flow of an external heat medium are counter flows. |
| US10988650B2 |
Non-flammable mixed refrigerant capable of reducing greenhouse effect and use thereof
Provided are a mixed refrigerant that is non-flammable and capable of reducing the greenhouse effect, and the use thereof. The mixed refrigerant comprises the following components in mass fractions: 10%-30% of R134a, 5%-70% of R1234ze(E), and 18%-65% of R1234yf. The mixed refrigerant of the present invention, in fitting combination with the amount ranges of all the components, makes the refrigerant non-flammable, and the ODP thereof is 0, and the GWP thereof is no greater than 400. The mixed refrigerant can be used in a refrigeration system, has no ozone destructive power, reduces the greenhouse effect, has a lower temperature glide, and belongs to ternary azeotropic or nearly azeotropic refrigerants, which is beneficial to the stable operation of a refrigeration system. The mixed refrigerant of the present invention can also serve as a foaming agent or aerosol propellant, and has the advantages of being non-flammable, having a low ozone destruction index, and being environmentally friendly and safe and reliable. |
| US10988649B2 |
Method for imparting water repellency to substrate, surface treatment agent, and method for suppressing collapse of organic pattern or inorganic pattern in cleaning substrate surface with cleaning liquid
A method for imparting water repellency to a substrate; a surface treatment agent used in the method; and a method for suppressing collapse of an organic or inorganic pattern in cleaning the substrate surface with a cleaning liquid. The method includes exposing a surface of a substrate to a surface treatment agent, the surface treatment agent including a water-repelling agent and a nitrogen-containing heterocyclic compound, the water-repelling agent including an alkoxymonosilane compound having a hydrophobic group bonded to a silicon atom. A surface treatment agent including a water-repelling agent and a nitrogen-containing heterocyclic compound, the water-repelling agent (A) including an alkoxymonosilane compound having a hydrophobic group bonded to a silicon atom. |
| US10988648B2 |
Elongated abrasive particle with enhanced retention features
The present inventive subject matter provides an abrasive particle. The abrasive particle can include an elongated body that is defined between opposed first and second ends. Each end defines a substantially planar surface. An axis extends through the first and second ends, and each end has a respective first and second cross-sectional area. At least one of the first and second ends is oriented at an angle relative to the axis that is less than 90 degrees. The elongated body has a variable cross-sectional area centered along the axis. At least one cross-sectional area between the first and second ends represents a local minimum cross-sectional area. |
| US10988646B2 |
Adhesive composition, and method of bonding an adherend and method of producing a stack, each of which uses the same
An adhesive composition, having: a polyalkylene oxide-added polyfunctional epoxy compound (a) represented by formula (A); a polyfunctional (meth)acrylate monomer (b), and a photo-acid generator (c); a method of bonding the adherends and a method of producing a stack, each of which uses the same: wherein R designates a lower alkylene group (e.g. an alkylene group having 1 to 4 carbon atoms); X designates a divalent linking group having a ring structure and 6 to 20 carbon atoms, or a lower alkylene group (e.g. an alkylene group having 1 to 4 carbon atoms); and m and n each are 0, or a positive number, independently. |
| US10988643B2 |
Starch and carboxylic acid binder compositions and articles made therewith
Fiber-containing composites are described that include woven or non-woven fibers, and a binder that holds the fibers together. The binder may include the reaction product of a starch and a polycarboxylic acid. The starch has a weight average molecular weight that ranges from 1×106 Daltons to 1×107 Daltons. The fiber-containing composite has an unaged tensile strength of greater than 4.0 and an aged tensile strength greater than 3.0. Also described are methods of making the fiber-containing composites. The methods may include applying a binder composition to fibers to form coated fibers, measuring a moisture content of the coated fibers, and curing the coated fibers in a curing oven to form the fiber-containing composite. The binder composition may include a starch having a weight average molecular weight that ranges from 1×106 Daltons to 1×107 Daltons, and a polycarboxylic acid. |
| US10988636B2 |
Polishing composition and method for manufacturing same, polishing method, and method for manufacturing substrate
To provide a polishing composition capable of polishing an object to be polished containing a silicon nitride film at a high polishing removal rate and reducing the particle residual amount on the object to be polished and a method for manufacturing the same, a polishing method, and a method for manufacturing a substrate.A polishing composition is a polishing composition containing abrasives, an anionic surfactant, and a dispersion medium, in which the anionic surfactant has at least one kind of acidic functional group selected from the group consisting of a sulfo group, a phosphate group, and a phosphonic acid group and a polyoxyalkylene group and the pH is less than 7 and which is used for polishing an object to be polished containing a silicon nitride film. |
| US10988633B2 |
Compound having isocyanuric skeleton and composition in which said compound is included
The invention aims to provide a novel compound to be suitably used for antifouling agents. The compound of the invention is represented by the following formula (1): wherein R1 is a monovalent organic group containing a polyether chain; X1 and X2 are each individually a monovalent group; and the polyether chain is a chain represented by the following formula: —(OC6F12)m11—(OC5F10)m12—(OC4F8)m13—(OC3X106)m14—(OC2F4)m15—(OCF2)m16—, wherein m11, m12, m13, m14, m15, and m16 are each individually an integer of 0 or 1 or greater; X10s are each individually H, F, or Cl; and the repeating units are present in any order. |
| US10988630B2 |
Coating compositions for building materials and coated building material substrates
Embodiments of the present disclosure are directed to coating compositions, coated articles, and methods in which the coated article is adapted to exhibit a particular permeance profile, such as, for example, a variable water vapor perm rating of about 1 perm or less at 25% average RH and about 15 perms or more at 95% average relative humidity, as tested by ASTM E96 at 21° C. |
| US10988628B2 |
Ink set and recording method using the same
An ink set includes a reaction liquid containing coagulant; a first ink containing a color material; and a second ink containing a color material. The ink set is used for recording on a non-absorptive recording medium or a low-absorptive recording medium and for imparting the reaction liquid, the first ink, and the second ink to the recording medium in a superimposed manner in this order. |
| US10988626B2 |
Corrosion inhibiting compositions and methods of making and using
A corrosion inhibiting composition includes one or more of a plurality of carriers, each having a carrier body and an organic corrosion inhibitor, such that the carrier body encapsulates the organic corrosion inhibitor, and the carrier body is formed of a degradable material. Coatings and methods for inhibiting corrosion on a metal substrate are also described herein. |
| US10988625B2 |
Curable silicone compositions that cure through command catalysis
Inhibited tin or titanate catalysts are used in condensation cures of silicone materials. Such catalysts are command cure systems with long open pot life, yet have relatively fast cure when the cure mechanism is triggered. This combines the advantages of the inhibited addition cure systems (command cure) with the advantages of the condensation cure systems (lower cost). |
| US10988623B2 |
Gloss removable coating
A coating composition comprises at least one solvent, at least one resin, and at least one filler, wherein the filler is silica-deficient, sodium-potassium alumina silicate. The silica-deficient filler may be a sodium-potassium alumina silicate that contains less than 0.1 percent by weight crystalline silica and is 5 percent by weight or less of the coating composition or 1 percent by weight or less of the coating composition. In the later instance, the coating composition contains less than 0.001 percent crystalline silica. The resin may comprise styrene, styrenic copolymers, or mixtures including styrene. The composition provides a temporary gloss coating that may be removed physically, as by peeling for example. A method for coating a substrate with a coating that maybe removed by physical means is also provided. The method comprises applying the disclosed coating composition. |
| US10988620B2 |
Composite element comprising a biphasic silica and carbon nanotube-based material
A composite material comprising at least one polymer matrix. The polymer matrix comprises at least one inorganic load composed of a biphasic material that comprises at least one mesoporous substrate at least partially coated with carbon nanotubes. The composite material is remarkable in that the mesoporous substrate is composed of diatoms. |
| US10988618B2 |
Self-assembled nano-structured particle and methods for preparing
Novel, nano-structured particles are formed by introducing a selected solid of interest into a structured fluid matrix formed by a dispersion of a small molecule host vessel components, such as a native or modified polysaccharide, cavitand, simple sugar, disaccharide, simple polyol or other similarly structured molecule known to be useful as a host vessel, in an acidic medium or other solvent, whereby the particle size of the introduced solid is reduced and or limited in the structured fluid matrix, by incorporation into or attachment to, the host vessel. The simple, one-batch mixing process results in stabilized colloidal dispersions of the nanoparticles of a variety of solids of varying scope and function and useful in a wide variety of applications, including without limitation ceramic materials, such as hexagonal boron nitride. |
| US10988615B2 |
Polyamide resin composition and molded article
Provided is a polyamide resin composition capable of yielding highly abrasion-resistant molded article, while keeping high mechanical strength, and, a molded article using the polyamide resin composition. The polyamide resin composition contains (A) polyamide resin, (B) polyolefin wax, and (C) at least one metal salt selected from alkali metal salt and alkali earth metal salt, and the (A) polyamide resin contains (a-1) semiaromatic polyamide resin. |
| US10988605B2 |
PVC compositions, films, laminates and related methods
Polyvinyl chloride compositions and films formed therefrom are described which exhibit improved printability and resistance to weathering. The compositions generally comprise polyvinyl chloride, at least one plasticizer, at least one heat stabilizer, certain UV stabilizer(s), and print additives and/or other agents. In particular versions, the compositions utilize a combination of polyvinyl chloride resins. Also described are various vinyl-based laminates using the films which can be for example reflective products. Also described are methods of producing the noted laminates. |
| US10988599B2 |
Method of producing plant biomass-based bioplastic
This invention relates to the field of producing bioplastics. Specifically, it relates to a method of producing all key ingredients of bioplastic making from pumpkins and making of bioplastic with these ingredients. More specifically, glycerin and other chemicals are extracted from pumpkin seed oil and mixed with starches that in the pumpkin flesh and then reinforced with pumpkin fibers to make bioplastic. The bioplastic produced with the method as disclosed in this invention possess superior properties in tensile strength and biodegradability compared to bioplastic made with petroleum derived glycerin. |
| US10988595B2 |
Urethane decomposing method and urethane decomposing agent
The purpose of the present invention is to provide a novel urethane decomposing method by which urethane in the environment is treated efficiently and at a low cost, and a urethane decomposing agent. The above purpose is attained by employing a urethane decomposing method including: a step of treating a urethane-containing material to be treated using an unsaturated fatty acid; and a step of making a microorganism belonging to a Streptomyces genus and exhibiting urethane decomposing function, to act on the material treated using the unsaturated fatty acid. |
| US10988594B2 |
Polycarbonate-based resin foam particle and foam molded body
Expanded particles of a polycarbonate-based resin containing a polycarbonate-based resin containing a component derived from bisphenol A as abase resin, the expanded particles being expanded particles of a polycarbonate-based resin satisfying any one of the following conditions (a) to (c) in a GC/MS chart: (a) a peak derived from a molecular weight of from 145 to 230 and a peak derived from a molecular weight of from 320 to 350 are shown; (b) a peak derived from a molecular weight of from 210 to 230 is shown; and (c) a peak derived from a molecular weight of from 290 to 320 is shown. |
| US10988581B2 |
Porous films obtained from polymer latex
The invention relates to a porous material comprising particles of polymer P assembled by a block copolymer, said block copolymer comprising at least one block consisting of a polymer sequence immiscible with polymer P, and at least two blocks consisting of polymer sequences which are miscible with polymer P. The invention also relates to films produced with this material. |
| US10988570B2 |
Molecules and oligomers for endothermic singlet fission
The present disclosure relates to a composition that includes a repeat unit defined by where each of R1, R2, R3, R4, R5, R6, R7, and R8 includes at least one of a hydrogen atom, a fluorine atom, and/or a first hydrocarbon chain having between 1 and 20 carbon atoms, inclusively, where each of A1, A2, A3 and A4 are either a carbon atom or a nitrogen atom, when A1 is a nitrogen atom, A2 is a carbon atom, when A2 is a nitrogen atom, A1 is a carbon atom, when A3 is a nitrogen atom, A4 is a carbon atom, when A4 is a nitrogen atom, A3 is a carbon atom, either A1 or A2 form a covalent bond, x, with a carbon atom, a, either A3 or A4 form a covalent bond, y, with a carbon atom, b, L is a linker group that includes an aromatic ring, and n is between 1 and 20, inclusively. |
| US10988569B2 |
Curable composition and cured product from same
Provided is a curable composition which has excellent curability, less causes silicone molds to swell, and allows the silicone molds to have better durability and a longer service life in repeated use. The curable composition according to the present invention is a curable composition for production of an optical component by molding using silicone molds. The curable composition contains curable compounds and a cationic initiator. The curable compounds include (A) a cycloaliphatic epoxy compound and (B) an oxetane compound. The oxetane compound (B) is present in a content of 10 to 45 weight percent of the totality of all the curable compounds contained in the curable composition. Of the totality of all the curable compounds contained in the curable composition, 90 weight percent or more is a compound or compounds having a solubility parameter of 9.0 (cal/cm3)½ or more as determined at 25° C. by the Fedors' method. |
| US10988565B2 |
Process for producing elastic and tear-resistant polyurethane foams and uses
The invention provides a process for producing polyurethane foams, in which compositions comprising A) isocyanate-functional prepolymers obtainable by the reaction of A1) low molecular weight diisocyanates of molar mass from 140 to 278 g/mol with A2) polyalkylene oxides having an OH functionality of two or more, A3) optionally further isocyanate-reactive components not covered by A2), B) water in an amount of at least 2% by weight, based on the total weight of the composition; C) optionally heterocyclic 4-membered or 6-membered ring oligomers of low molecular weight diisocyanates having a molar mass of 140 to 278 g/mol; D) optionally catalysts; E) optionally salts of weak acids, the corresponding free acids of which have a pKA in water at 25° C. of ≥3.0 and ≤14.0; F) optionally surfactants; G) optionally mono- or polyhydric alcohols or polyols, and H) optionally hydrophilic polyisocyanates obtainable by reaction of H1) low molecular weight diisocyanates of molar mass from 140 to 278 g/mol and/or polyisocyanates preparable therefrom and having an isocyanate functionality of 2 to 6 with H2) monofunctional polyalkylene oxides of OH number from 10 to 250 and of ethylene oxide content from 50 to 100 mol %, based on the total amount of the oxyalkylene groups present, are provided, foamed and cured, wherein the isocyanate-containing components, especially components A, C and H, have a total isocyanate content within a range from 2% to 8% by weight and a content of urethane groups of 1.0 to 3.5 mol/kg, based in each case on the total amount of the isocyanate-containing components, and also the foams thus produced and the uses thereof. |
| US10988560B2 |
Method for producing carboxyl-group-containing polymer composition
There is provided a method for producing a carboxyl group-containing polymer composition that is excellent in all of the following: dispersibility in water or the like immediately after the preparation, storage stability, and the transparency of a neutral viscous solution thereof. A method for producing a carboxyl group-containing polymer composition, the carboxyl group-containing polymer composition comprising a carboxyl group-containing polymer (A) that is a copolymer of monomers comprising an α,β-unsaturated carboxylic acid (a-1) and a compound (a-2) having at least two ethylenically unsaturated groups per molecule; and a nonionic surfactant (B), the method comprising the step of copolymerizing the monomers, wherein in the step, the nonionic surfactant (B) is added into the system when the polymerization degree of the α,β-unsaturated carboxylic acid (a-1) has reached 70 to 100%. |
| US10988559B2 |
Fluoropolymer powder and method for producing same
The invention provides a powder that is easily redispersible in a liquid medium such as water. The powder contains a fluoropolymer. The fluoropolymer contains at least one group A selected from the group consisting of —SO2Y, —COOR, —SO3X, —SO2NR12, and —COOX, wherein Y is a halogen atom; R is a C1-C4 alkyl group; X is M1/L or NR14, where M is a hydrogen atom or an L-valent metal, the L-valent metal being a metal in group 1, group 2, group 4, group 8, group 11, group 12, or group 13 of the periodic table; and R1s are each individually a hydrogen atom or a C1-C4 alkyl group. The powder exhibits a dispersion of 50% or higher. The dispersion is calculated by filtering a composition obtainable by mixing the powder with water through a mesh having an opening of 20 μm. |
| US10988558B2 |
Controlled particle size distribution
Provided is a method of making a collection of polymer beads comprising (a1) forming a first collection of monomer droplets in an aqueous medium in a container, wherein the first collection of monomer droplets has volume-average diameter DAV1 and has uniformity coefficient less than 1.3; (a2) forming a second collection of monomer droplets in the aqueous medium in the container, wherein the second collection of monomer droplets has volume-average diameter DAV2 and has uniformity coefficient less than 1.3, wherein DAV1 and DAV2 differ by 10 μm or more; wherein either step (a1) and step (a2) are performed simultaneously; or step (a2) is performed after step (a1), while the first collection of monomer droplets remains in the container; or a combination thereof; and (b) after steps (a1) and (a2), polymerizing the monomer droplets by suspension polymerization to form the polymer beads. |
| US10988557B2 |
Methods of preparing a catalyst utilizing hydrated reagents
A method of preparing a catalyst comprising a) contacting a titanium-containing compound, a solvating agent, and a solvent to form a solution; b) contacting the solution with a chrominated silica-support to form a pre-catalyst; and c) thermally treating the pre-catalyst by heating to a temperature of from about 400° C. to about 1000° C. for a time period of from about 1 minute to about 24 hours to form the catalyst. |
| US10988556B2 |
Cationic polymers and porous materials
According to one or more embodiments, cationic polymers may be produced which include one or more monomers containing cations. Such cationic polymers may be utilized as structure directing agents to for mesoporous zeolites. The mesoporous zeolites may include micropores as well as mesopores, and may have a surface area of greater than 350 m2/g and a pore volume of greater than 0.3 cm3/g. Also described are core/shell zeolites, where at least the shell portion includes a mesoporous zeolite material. |
| US10988553B2 |
Catalyst pre-contact device for continuous polymerization of olefins and method for catalyst pre-contact
Disclosed is a catalyst pre-contact method for the continuous polymerization of an olefin, wherein a primary catalyst, a co-catalyst and, optionally, an external electron donor are mixed and then undergo a pre-contact reaction, with the pre-contact reaction temperature being −30° C. to 35° C. and adjustable, and the pre-contact reaction time being 0.5 min to 10 min and adjustable, and the pre-contacted catalyst is brought into a catalyst prepolymerization system and then into a catalyst polymerization system, or is directly brought into the catalyst polymerization system. Further disclosed is a catalyst pre-contact device for the continuous polymerization of an olefin, which can adjust the pre-contact time and pre-contact temperature of the catalyst so that the performance of the catalyst achieves a better level according to the process. |
| US10988552B2 |
Antibodies targeted to fungal cell wall polysaccharides
A compound comprising one or more polysaccharide moieties each independently represented by the formula β(1→4)-[GlcNH—R]n-2,5-anhydromannose, wherein n is a positive integer from 3 to 500, and R is H or an acyl group, is described. The compound can be manufactured by (a) reacting chitosan with an acylating agent sufficient to partially N-acylate the chitosan, yielding a modified chitin/chitosan mixed polymer; and (b) reacting the modified chitin/chitosan mixed polymer with a deaminating agent to cleave the mixed polymer at the unacylated chitosan moieties. The compound can be used to immunize against fungal infection. Antibodies specific to the compound, and the use of such antibodies to protect against fungal infection are also described. |
| US10988549B2 |
Method for producing cellulose nanofiber dry solid
A method for producing a dry solid of cellulose nanofiber, the method comprising (A) preparing a dispersion in which cellulose nanofiber with an average fiber diameter of 2 to 500 nm is dispersed in a mixed solvent of water and a water-soluble organic solvent; and (B) drying the dispersion. |
| US10988545B2 |
Anti-GITR antigen-binding proteins and methods of use thereof
Provided herein are antigen-binding proteins (ABPs) that selectively bind to GITR and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods. |
| US10988544B2 |
Fusion proteins comprising an anti-CD40 antibody and HIV antigenic peptides
The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies. |
| US10988537B2 |
Antibodies comprising chimeric constant domains
Antibodies, antigen-binding proteins and Fc-fusion proteins that comprise recombinant polypeptides containing a chimeric heavy chain constant region sequence are provided that bind to certain Fc receptors however have reduced effector functions. Methods of making constructs for expression of such chimeric Fc-containing antibodies, antigen-binding proteins and Fc-fusion proteins in cell systems, and methods of producing and isolating the chimeric Fc-containing proteins are provided. |
| US10988536B2 |
Human antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof
The present disclosure provides isolated monoclonal antibodies that specifically bind to LAG-3 with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human LAG-3. In certain embodiments, the antibodies bind both human and monkey LAG-3 but do not bind mouse LAG-3. The invention provides anti-LAG-3 antibodies that can inhibit the binding of LAG-3 to MHC Class II molecules and that can stimulate antigen-specific T cell responses. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. This disclosure also provides methods for detecting LAG-3, as well as methods for treating stimulating immune responses using an anti-LAG-3 antibody of the invention. Combination therapy, in which an anti-LAG-3 antibody is co-administered with at least one additional immunostimulatory antibody, is also provided. |
| US10988532B2 |
Anti P2X7 receptor antibodies and fragments thereof
The invention relates to an antigen binding site for binding to a P2X7 receptor, the antigen binding site being defined by general formula 1: FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4. |
| US10988531B2 |
Conjugates comprising cell-binding agents and cytotoxic agents
The invention relates to novel cell-binding agent-cytotoxic agent conjugates, wherein the cell-binding agent (CBA) is covalently linked to the cytotoxic agent through an aldehyde group obtained from oxidation of a 2-hydroxyethylamine moiety on the CBA. The invention also provides methods of preparing the conjugates of the present invention. The invention further provides composition and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the conjugates of the invention. |
| US10988529B2 |
Combination therapy
A method of treating a cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of an anti-N3pGlu Abeta antibody, an anti-Abeta antibody, or an antibody fragment that binds Amyloid beta and is covalently attached to a polyethylene glycol molecule, in combination with an effective amount of an anti-Tau antibody. |
| US10988527B2 |
Method for preparing TNFR-Fc fusion protein containing target content of impurities
The present invention relates to a method for preparing a TNFR-Fc fusion protein mixture comprising a target content of hydrophobic chromatogram peak 3, and to a method for adjusting a content of hydrophobic chromatogram peak 3. Specifically, the present invention relates to (a) a method for preparing a TNFR-Fc fusion protein mixture using a hydrophobic interaction chromatograph medium containing an aromatic functional group, which is pre-equilibrated with an equilibration buffer comprising sodium chloride or ammonium sulfate, and a sample comprising a TNFR-Fc fusion protein mixture liquid produced from mammalian cells, and to a method for adjusting the content of hydrophobic chromatogram peak 3 by hydrophobic chromatography using an equilibration buffer containing a predetermined concentration of sodium chloride or ammonium sulfate. |
| US10988526B2 |
DNA molecule encoding a p75NTR(NBP)-Fc fusion protein
The present invention relates to a p75NTR neurotrophin binding protein (NBP)-Fc fusion protein comprising a p75NTR(NBP) portion and an immunoglobulin portion. In certain embodiments, the p75NTR(NBP)-Fc fusion protein is for use in the treatment of pain and/or a symptom of pain. |
| US10988524B2 |
Modified relaxin B chain peptides and their therapeutic use
Provided is a biologically active single chain Relaxin peptide having the following formula (I): Nter-X-(E)a-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-R-(X32)b-(X33)c-(X34)d-NH2-Cter. Also provided is a pharmaceutical composition comprising at least one peptide of the invention, or a pharmaceutically acceptable salt or a solvate thereof. Further provided is the peptide, a pharmaceutically acceptable salt or solvate thereof, or the pharmaceutical composition for use as a medicament. |
| US10988523B2 |
Modified lipidated Relaxin B chain peptides and their therapeutic use
Provided is a biologically active single chain Relaxin peptide having the following formula (I): Nter-Ac-(E)a-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-R-(X32)b-(X33)c-(K)d-(X35)e-(gE)f-X37-Cter; or a salt or solvate thereof. Also provided is a pharmaceutical composition comprising at least one peptide of the invention, and the peptide or the pharmaceutical composition for its use as a medicament. |
| US10988521B1 |
Recombinant milk proteins
Provided herein are compositions and methods for producing recombinant milk proteins, as well as food compositions comprising the same. In aspects, the recombinant milk proteins of the disclosure are recombinant fusion proteins comprising casein and beta-lactoglobulin. |
| US10988520B2 |
Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
The present disclosure is directed to a lysin-AMP polypeptide construct comprising: (a) a first component comprising the polypeptide sequence of: (i) SEQ ID NO: 118 (GN202); or (ii) a polypeptide having lysin activity and having at least 80% sequence identity with the polypeptide sequence of SEQ ID NO: 118 (GN202); or (iii) an active fragment of SEQ ID NO: 118 (GN202); and (b) a second component comprising the polypeptide sequence of at least one antimicrobial peptide (AMP), wherein the at least one AMP comprises SEQ ID NO: 114 (FIRL). Exemplary lysin-AMP polypeptides, such as GN370 (SEQ ID NO: 44) as well as methods of treating bacterial infections using the present lysin-AMP polypeptide constructs are also disclosed. |
| US10988519B2 |
Composition and method for treating complement-mediated disease
Provided herein is a recombinant viral vector having packaged therein an expression cassette comprising an engineered complement regulator factor H (fH), wherein the gene encodes a hfH protein variant comprising short consensus repeats (SCRs) 1-4, 6-8, and 17-20. Pharmaceutical compositions containing this vector and plasmids comprising nucleic acid sequences that encode the fH protein variant are also provided. |
| US10988518B2 |
Method for efficiently producing β myosin heavy chain in cardiac muscle cells differentiated from induced pluripotent stem cells derived from Homo sapiens
The present invention provides a method for producing a β myosin heavy chain in cardiac muscle cells differentiated from induced pluripotent stem cells derived from Homo sapiens. In the present method, first, a liquid culture medium containing the cardiac muscle cells is supplied onto a substrate comprising a first electrode, a second electrode and insulative fibers on the surface thereof. At least a part of the insulative fibers is located between the first electrode and the second electrode in a top view of the substrate. Then, the substrate is left at rest. Finally, the cardiac muscle cells are cultivated, while a pulse electric current is applied to the cardiac muscle cells through the first electrode and the second electrode. |
| US10988514B2 |
Polypeptdes capable of forming homo-oligomers with modular hydrogen bond network-mediated specificity and their design
Methods and apparatus for identifying and screening hydrogen bond networks are provided. A computing device can determine a search space for hydrogen bond networks related to one or more molecules, where the search space can include a plurality of energy terms related to a plurality of residues related to the hydrogen bond networks. The computing device can search the search space to identify one or more hydrogen bond networks based on the plurality of energy terms. The computing device can screen the identified hydrogen bond networks to identity one or more screened hydrogen bond networks based on scores for the identified hydrogen bond networks. An output can be generated that is related to the one or more screened hydrogen bond networks. Also provided are polypeptides that can form homo-oligomers with modular hydrogen bond network-mediated specificity. |
| US10988513B2 |
Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds
The present disclosure relates to the use of a maltose dependent degron to control stability of a protein of interest fused thereto at the post-translational level. The present disclosure also relates to the use of a maltose dependent degron in combination with a maltose-responsive promoter to control gene expression at the transcriptional level and to control protein stability at the post-translational level. The present disclosure also relates to the use of a stabilization construct that couples expression of a cell-growth-affecting protein with the production of non-catabolic compounds. The present disclosure further relates to the use of a synthetic maltose-responsive promoter. The present disclosure further provides compositions and methods for using a maltose dependent degron, a maltose-responsive promoter, and a stabilization construct, either alone or in various combinations, for the production of non-catabolic compounds in genetically modified host cells. |
| US10988512B2 |
Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses
The present invention is a DNA expression vector comprising: a toxP; a mutant toxO that blocks Fe-mediated regulation of gene expression; and a DNA sequence encoding a protein, wherein the toxP and the mutant toxO regulate expression of the DNA segment encoding the protein. It is preferred that DNA expression vectors of the present invention include DNA sequences encoding a signal peptide so that a protein expressed is attached to the signal peptide prior to processing. Novel proteins are produced off of the DNA expression vector of the present invention. |
| US10988507B2 |
Immunomodulators
The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases. |
| US10988506B2 |
Cyclic tetrapeptide stereoisomers
Cyclic tetrapeptide stereochemical isomers of CJ-15,208, pharmaceutical compositions from such cyclic tetrapeptides, and methods of using such pharmaceutical compositions. The cyclic tetrapeptide compounds and pharmaceutical compositions disclosed herein are potent analgesics active in several pain models with generally minimal tolerance and reduced likelihood to induce addiction relative to other known opiates. |
| US10988505B2 |
Matriptase inhibitors and uses thereof
The present application relates to a compound of formulae (I), (II) or (III) or a pharmaceutically acceptable salt thereof, methods and uses thereof for treating disorders associated with matriptase activity. |
| US10988500B2 |
Lipid A mimics, methods of preparation, and uses thereof
The invention provides lipid A mimics in which one or both of the sugar residues of a natural lipid A disaccharide backbone has been replaced with an aromatic group. These lipid A mimics may further differ from a natural lipid A molecule with respect to other structural characteristics, such as, a different number of phosphate groups present, changes in the number, structure and location of lipid chains and/or changes in the spacing and linkage of the sugar residues (or their aromatic replacements). The lipid A mimics may be lipid A agonists and as such may be useful as immunostimulatory agents in inducing or patenting an antibody and/or cell-mediated immune response, or may be lipid A antagonists and as such may be useful in treating or preventing a lipopolysaccharide (LPS)/lipid A-mediated disease or disorder. Also provided are methods for preparing the lipid A mimics. |
| US10988478B1 |
Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators
Compounds of Formula 0, Formula I, and Formula II and methods of use as Interleukin-1 Receptor Associated Kinase (IRAK4) inhibitors are described herein. |
| US10988477B2 |
GCN2 inhibitors and uses thereof
The present invention provides compounds inhibiting General amino acid Control Non-derepressible 2 kinase (“GCN2”), compositions thereof, and methods of using the same for treating various disorders, such as cancer. |
| US10988472B2 |
Compounds and method for blocking transmission of malarial parasite
Disclosed are compounds of formula (I) and formula (II): (I) (II) wherein R1, R2, A, and B are as defined herein. Also disclosed is a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria comprising administering to an animal an effective amount of a first compound of formula (I) or (II) either alone or in combination with a second compound selected from elesclomol, NSC174938, NVP-AUY922, Maduramicin, Narasin, Alvespimycin, Omacetaxine, Thiram, Zinc pyrithione, Phanquinone, Bortezomib, Salinomycin sodium, Monensin sodium, Dipyrithione, Dicyclopentamethylene-thiuram disulfide, YM155, Withaferin A, Adriamycin, Romidepsin, AZD-1152-HQPA, CAY10581, Plicamycin, CUDC-101, Auranofin, Trametinib, GSK-458, Afatinib, and Panobinostat. |
| US10988469B2 |
Method for producing optically active compound
The aim of the present invention is to provide a method capable of producing an optically active pyrimidinamide derivative on an industrial scale.Compound (I) or a salt thereof is subjected to an asymmetric reduction reaction, the obtained compound (II) or a salt thereof is subjected to a deprotection reaction, and the obtained compound (III) or a salt thereof is reacted with compound (VI) or a salt thereof to obtain compound (V) or a salt thereof. wherein each symbol is as defined in the specification. |
| US10988468B2 |
Nitrogen-containing 6-membered cyclic compound
A novel compound represented by the following general formula (1), or a salt thereof, which has a superior EP4 receptor agonist activity, and a medicament containing the compound or a salt thereof as an active ingredient, which can be used for promotion of osteogenesis, therapeutic treatment and/or promotion of healing of fracture and the like. |
| US10988467B2 |
Compounds as ROR gamma modulators
The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein ring A, ring B, L, R1, R2, R3, R4, R5, Ra, Rb, n, m, p and q are as defined herein, which are active as modulators of retinoid-related orphan receptor gamma t (RORγt). These compounds prevent, inhibit, or suppress the action of RORγt and are therefore useful in the treatment of RORγt mediated diseases, disorders, syndromes or conditions such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer. |
| US10988466B2 |
Heterocyclic derivatives useful as SHP2 inhibitors
This invention relates to certain novel pyrazine derivatives (Formula I) as SHP2 inhibitors which is shown as formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention is directed to fused heterocyclic group derivatives useful as inhibitors of SHP2, methods for producing such compounds and methods for treating a SHP2-mediated disorder. |
| US10988463B2 |
Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors
Provided herein are substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof. |
| US10988461B2 |
Small molecule IRE1-α inhibitors
Described herein are IRE1α inhibitors, compositions containing such inhibitors, and methods of treatment that include administration of such compounds. Exemplary compounds are provided throughout the application. |
| US10988457B2 |
TLR inhibitors
A method for inhibiting TLR7 and/or TLR8 receptors includes contacting the receptor with compound of general formula (I): wherein the meanings of the variables are explained in the specification, or a stereoisomeric form or a mixture of stereoisomeric forms, or pharmaceutically acceptable salts thereof. A pharmaceutical composition can include compounds of the invention, which can be used in a method for inhibiting TLR7 receptors and/or TLR8 receptors. The method can be performed by administering the compound to a subject to inhibit TLR7, TLR8, or TLR7/8 activity, which can be used to treat a disease or disorder associated with the receptors. |
| US10988452B2 |
Method producing for 5-hydroxymethyl-2-furfural with suppressed by-product formation
An object of the present invention is to provide a method for producing 5-hydroxymethyl-2-furfural (5-HMF) with suppressed production of byproducts. The present invention provides a method for producing 5-HMF, comprising the step of performing a dehydration reaction of a carbohydrate comprising a hexose as a constituent sugar or a derivative thereof to produce 5-hydroxymethyl-2-furfural, wherein the dehydration reaction is performed in the presence of activated carbon. The present invention also provides a method for producing a carbohydrate composition comprising 5-hydroxymethyl-2-furfural, comprising the step of heating a carbohydrate composition comprising one or more selected from the group consisting of a carbohydrate comprising a hexose as a constituent sugar and a derivative thereof, in the presence of an acid catalyst and activated carbon at a temperature of 90 to 400° C. |
| US10988449B2 |
Isoxazole derivatives as nuclear receptor agonists and uses thereof
The present invention relates to isoxazole derivatives, including pharmaceutical compositions and for the preparation of isoxazole derivatives. And more particularly the present invention provided a pharmaceutical composition of isoxazole derivatives for activation of Farnesoid X receptor (FXR, NR1H4). |
| US10988448B2 |
Therapeutic compounds and compositions
Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer. |
| US10988446B2 |
Concise process for preparing 3-pyrrolidine carboxylic acid derivatives
The present invention relates to a process for preparing 3-pyrrolidine carboxylic acid derivatives, and particularly a simple process for preparing 5-substituted 3-pyrrolidine carboxylic acid derivatives. In addition, the present invention relates to a novel pyrrolidine carboxylic acid derivative, its manufacture, pharmaceutical compositions containing it and its use as a catalyst. |
| US10988443B2 |
Methods for improved production of vitamins D2 and D3
It is an object of the present invention to provide methods for producing vitamin D that gives improved yields and reduced side product contamination. In various aspects, these methods provide for production of vitamin-D2 using ergosterol as provitamin D2 or a dihydroxy derivative thereof as a starting material, or production of vitamin-D3 using 7-dehydrocholesterol as provitamin D3 or a dihydroxy derivative thereof as the starting material. The methods described herein comprise irradiating the starting material in a solution including an organic or inorganic base with light in the wavelength range 245-360 nanometers (nm) to obtain a product containing pre-vitamin-D2 or pre-vitamin-D3, and heating the product to convert the resulting pre-vitamin-D2 or pre-vitamin-D3 to vitamin D2 or vitamin D3. In various embodiments, these methods further comprise recovering vitamin D2 or vitamin D3 from this reaction as a purified product. |
| US10988440B2 |
FTO inhibitors
The invention provides compounds that inhibit FTO (fat mass and obesity), including pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof, particularly obesity, with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition. |
| US10988439B2 |
Cytotoxic compounds, pharmaceutical compositions thereof, and methods of treating cancer
Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin. |
| US10988437B1 |
Bis(aniline) compounds containing multiple substituents with carbon-carbon triple-bonded groups
The invention relates to bis(aniline) compounds containing multiple arylethynyl, alkylethynyl, ethynyl groups or their combinations, processes of making such compounds and materials comprising such compounds. Such, bis(aniline) compounds preferably comprise multiple phenylethynyl (PE) groups, i.e. 2-4 PE moieties. Such compounds are useful monomers for the preparation of polyimides, polyamides and poly(amide-imides) whose post-fabrication crosslinking chemistry (i.e. reaction temperature) can be controlled by the number of PE per repeat unit as well as finding utility in thermosetting matrix resins, 3D printable resins, and as high-carbon-content precursors to carbon-carbon composites. |
| US10988435B2 |
Treprostinil derivatives and compositions and uses thereof
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension. |
| US10988430B2 |
Continuous process for the conversion of olefins and carbon dioxide to acrylates via solution phase reactor
Disclosed is a continuous process for producing α,β-unsaturated carboxylic acids or salts thereof, comprising: 1) in a first stage, contacting (a) a transition metal precursor compound comprising at least one first ligand, (b) optionally, at least one second ligand, (c) an olefin, (d) carbon dioxide (CO2), and (e) a diluent to form a first composition; 2) in a second stage, contacting a polyanionic solid with the first composition to form a second composition; and 3) in a third stage, (a) contacting the second composition with a polar solvent to release a metal salt of an α,β-unsaturated carboxylic acid and form a reacted solid. Methods of regenerating the polyanionic solid are described. |
| US10988423B2 |
Gas-phase catalytic fluorination with chromium catalysts
A process for the fluorination of a chlorinated C3 alkane or alkene compound having at least one chlorine atom into a fluorinated C3 alkane or alkene compound having at least one fluorine atom includes the following steps: a) contacting, in a reactor, the chlorinated compound with hydrogen fluoride in gas phase in the presence of a fluorination catalyst to produce a fluorinated compound, and b) regenerating the fluorination catalyst used in step a). The step (b) of regenerating the fluorination catalyst comprises (c) the treatment of said fluorination catalyst with an oxidizing agent-containing gas flow to form an oxidized fluorination catalyst, and (d) the treatment of the oxidized fluorination catalyst obtained in step (c) with a gaseous mixture comprising a reducing agent and an inert gas. The catalyst regenerated in step b) is reused in step a) and the reducing agent is selected from C1-C10 hydrohalocarbons. |
| US10988419B2 |
Binders for the granulation of fertilizers
According to some demonstrative embodiments, there is provided herein a fertilizer granule including a fertilizer dust and one or more binders wherein said granule comprises a single strength of at least 2.5 kg/gran and a single strength after humidity chamber 24 hours, 79% RH of at least 0.5 kg/granule. |
| US10988413B2 |
Calcium sulphate-based products
This invention relates to improved high temperature resistant calcium sulphate-based products e.g. gypsum wallboard products and, in particular, to products having reduced shrinkage at high temperatures. The invention provides calcium sulphate-based product comprising gypsum and a shrinkage resistance additive. The shrinkage resistance additive is melamine polyphosphate or melamine pyrophosphate. |
| US10988412B2 |
Formaldehyde-free binder compositions and methods of making the binders under controlled acidic conditions
Formaldehyde-free binder compositions are described that include an aldehyde or ketone, a reaction product between a polyamine and an organic anhydride, and an acidic compound. The acidic compound may be an organic acid, an acidic catalyst, or both. The acidic compound is supplied in quantities that lower the pH of the binder composition to about 5 or less. The binder compositions may be used in methods of binding fiberglass and the resulting fiberglass products have an improved tensile strength due to the addition of the acidic compound. |
| US10988408B2 |
Conversion material for white or colored light source, method of production, and light source having the conversion material
A conversion material for a white or colored light source is provided. The material includes a matrix glass that, as bulk material, for a thickness of about 1 mm, has a pure transmission of greater than 80% in the wavelength region from 350 to 800 nm and in the region in which the primary light source emits light, wherein the sum of transmission and reflection of the sintered matrix glass without luminophore is at least greater than 80% in the spectral region from 350 nm to 800 nm and in the spectral region in which the primary light source emits light. |
| US10988407B2 |
Manufacturing process for striae-free multicomponent chalcogenide glasses via multiple fining steps
The present invention provides for synthesizing high optical quality multicomponent chalcogenide glasses without refractive index perturbations due to striae, phase separation or crystal formation using a two-zone furnace and multiple fining steps. The top and bottom zones are initially heated to the same temperature, and then a temperature gradient is created between the top zone and the bottom zone. The fining and cooling phase is divided into multiple steps with multiple temperature holds. |
| US10988402B2 |
Trim element for interior vehicle
The invention relates to a trim element for interior vehicle. According to the invention, the trim element is made of glass sheet. |
| US10988400B2 |
Transparent sealing member
The present invention relates to a transparent sealing member. A quartz glass transparent sealing member is used in an optical component having at least one optical element, and a mounting board on which the optical element is mounted, and constitutes, with the mounting board, a package that houses the optical element. The concentration of aluminum in a surface portion is higher than the concentration of aluminum in an inner portion. |
| US10988398B2 |
Molding material for 3D printing based on crushed amorphous glass having irregular shape, molding method for 3D printing, and molded body
The present invention relates to a forming material for three-dimensional (3D) printing, a forming method for 3D printing, and a formed object, wherein, while being based on an amorphous glass powder shaped irregularly, the forming material for 3D printing ensures excellent flowability and sinterability such that it enables the formation of high-quality products at high speed. The forming material for 3D printing consists of a parent glass powder in the form of an unmelted powder irregularly shaped by crushing amorphous glass; and a spherical nanopowder that has an average particle diameter equal to or less than 1/50th of the average particle diameter of the parent glass powder and is mixed in such a way that it can be disposed on a surface of the parent glass powder to enhance the flowability of the irregularly shaped parent glass powder during the formation of an object by 3D printing. |
| US10988397B2 |
Integrated greening device and method for recycling wastewater
The present invention discloses a small integrated greening device and method for recycling wastewater, including a wastewater collection system, a microorganism and plant purification system, and a reclaimed water collection and distribution system. The method includes the following process: greywater or wastewater is collected through a pipeline and enters a water collection tank of a wastewater collection part. Lifting is performed by submersible sewage pumps, such that the lifted water enters a microorganism and plant synergistic purification and greening part. Each submersible pump is controlled by one corresponding automatic water level controller to transport the treated water to the reclaimed water-use sites. The device and method provided by the present invention utilize the physical and chemical action of a filler and the synergistic purification effect of microorganisms and plants to purify the greywater, and the purified reclaimed water is used for flushing toilets, watering trees or other purposes. |
| US10988394B2 |
Cost control of wastewater treatment based on regulatory period
Techniques for controlled aeration (140) of wastewater (190) include determining a first aeration intensity for a first aeration interval and a different second aeration intensity for a second aeration interval (225) based on a current energy price (215), a predicted energy price (221), and a regulatory surveillance period (201) during which a regulated critical parameter is monitored for regulatory compliance. Wastewater is aerated at the first aeration intensity for the first aeration interval; and at the second aeration intensity for the second aeration interval. The first aeration interval is short compared to the regulatory surveillance period, the second aeration interval is short compared to the regulatory surveillance period and does not overlap the first aeration interval, and the first aeration intensity is less than the second aeration intensity. |
| US10988391B2 |
Desalination electrode
A desalination battery includes a container configured to contain a saline water solution having a first concentration c1 of dissolved salts; first and second intercalation hosts, arranged to be in fluid communication with the saline water solution, at least the first intercalation host including expanded graphite having a plurality of graphene layers with an interlayer spacing between the graphene layers in z-direction greater than 0.34 nm; and a power source configured to supply electric current to the first and second intercalation hosts such that the first and second intercalation hosts reversibly store and release cations and anions from the saline water solution located between the plurality of graphene layers to generate a fresh water solution having a second concentration c2 of dissolved salts and a brine solution having a third concentration c3 of dissolved salts within the container such that c3>c1>c2. |
| US10988386B1 |
Separation and purification of rare-earth elements by chemical reduction in aqueous solutions
The subject matter described herein includes a method of separating a mixture of trivalent rare-earth elements, based on their reduction potential, and solubility in a divalent state. The method includes adding the mixture of trivalent rare-earth elements to a tetraborate salt with deionized water to form a salt mixture, grinding the salt mixture with boric acid to form a solid mixture, wetting the solid mixture with water to form a paste, heating the paste to form a resultant product, dissolving the resultant product, thereby creating a residual solid in aqueous solution, wherein the residual solid includes a second mixture of trivalent rare-earth elements, and the aqueous solution includes a substantially singular element of a divalent rare-earth element in an aqueous state, and removing the residual solid, thereby separating the divalent rare-earth element from the mixture of trivalent rare-earth elements. |
| US10988384B2 |
Graphite-sheet processed article and graphite sheet processed article manufacturing method
In order to attain an object to achieve a graphite sheet processed product which is made of high quality graphite and which has a smooth cut surface even after being subjected to a cut process, a graphite sheet processed product of the present invention has a thickness of not less than 10 nm and not more than 20 μm, has a cross-sectional area 90% or more of which is occupied by graphite layers each extending continuously or discontinuously in a horizontal direction, the cross-sectional area being observed with use of a scanning electron microscope (SEM), includes therein graphite crystal having an average crystal grain size of not less than 0.35 μm and not more than 25 μm, and has, on a cut surface thereof, a burr having a size that is not more than 15% of a line width thereof, the line width being less than 400 μm. |
| US10988378B2 |
Pilot plant for chemical looping hydrogen generation using single-column packed bed and hydrogen generation method
A pilot plant for chemical looping hydrogen generation using a single-column packed bed and hydrogen generation method. The plant has a feeding system, reaction system, tail gas treatment and analysis system, and auxiliary system. The reaction system has a packed bed reactor, inside which a thermal storage layer, oxygen carrier layer and supporting layer are arranged successively from top to bottom. The feeding system has a delivery pipe, metering pump, mass flow controller and fuel mixer. The tail gas treatment and analysis system has a cooler, gas-liquid separator, mass flow meter, gas analyzer and tail gas pipe. The packed bed reactor is subjected to fuel reduction, purge, steam oxidation, purge, air combustion and purge stages successively under control of the feeding system. The pilot plant enables evaluation for oxygen carriers and identification for technological difficulties and can generate high-purity hydrogen without using complex gas purification devices. |
| US10988376B2 |
Monolithic integration of piezoelectric micromachined ultrasonic transducers and CMOS and method for producing the same
A method of forming a monolithic integrated PMUT and CMOS with a coplanar elastic, sealing, and passivation layer in a single step without bonding and the resulting device are provided. Embodiments include providing a CMOS wafer with a metal layer; forming a dielectric over the CMOS; forming a sacrificial structure in a portion of the dielectric; forming a bottom electrode; forming a piezoelectric layer over the CMOS; forming a top electrode over portions of the bottom electrode and piezoelectric layer; forming a via through the top electrode down to the bottom electrode and a second via down to the metal layer through the top electrode; forming a second metal layer over and along sidewalls of the first and second via; removing the sacrificial structure, an open cavity formed; and forming a dielectric layer over a portion of the CMOS, the open cavity sealed and an elastic layer and passivation formed. |
| US10988375B1 |
Systems, methods, and devices for mechanical isolation or mechanical damping of microfabricated inertial sensors
MEMS-based sensors can experience undesirable signal frequencies caused by vibrations, shocks, and accelerations, among other phenomena. A microisolation system can isolate individual MEMS-based sensors from undesirable signal frequencies and shocks. An embodiment of a system for microisolation of a MEMS-based sensor can include an isolation platform connected to one or more folded springs. Another embodiment of a system for microisolation can include an isolation platform and/or a frame connected to a mesh damping mechanism. In at least one embodiment, a mesh damping mechanism can be a microfibrous metal mesh damper. In one or more embodiments, a system for microisolation can include an isolation platform connected to one or more L-shaped springs, and a thickness of the one or more L-shaped springs can be less than a thickness of the isolation platform. |
| US10988374B2 |
Device for supporting a MEMS component
The invention relates to a device for supporting a MEMS component, especially a pressure sensor, having a substrate formed of a ceramic, a MEMS component on the substrate and walls forming a cavity for surrounding the MEMS component, in which the walls are formed from a machined ceramic cavity array. |
| US10988372B2 |
MEMS device with reduced electric charge, cavity volume and stiction
A method includes forming a first mask on a first portion of a first surface of a substrate, forming a second mask on the first mask and further forming the second mask on a second portion of the first surface of the substrate, and etching an exposed portion of the first surface of the substrate and removing the second mask. According to some embodiments, an exposed portion of the first surface of the substrate is etched and the first mask is removed. An oxide layer is formed on the first surface of the substrate. A third mask is formed on the oxide layer except for a portion of the oxide layer corresponding to bumpstop features. The portion of the oxide layer corresponding to the bumpstop features is removed. An exposed portion of the first surface of the substrate is etched and the third mask is removed. |
| US10988370B2 |
Signal-controlled flow fuel delivery valve
The invention concerns a delivery valve for the delivery of a fluid into a tank of a motor vehicle. According to the invention, the following is provided: a) the delivery valve has a first settable maximum volume flow, b) the delivery valve has a second settable maximum volume flow which is higher than the first settable maximum volume flow, c) a control device (24, 25), by means of which optionally the first or the second maximum volume flow can be set, d) a sensor device (20, 21), which is configured for interaction with a signal emitter (29) assigned to the tank of the motor vehicle and which activates the control device. |
| US10988364B2 |
Carbonation tank assembly
The invention provides a carbonation tank assembly for admixing a gas and a potable liquid used in preparation of drinks. The assembly includes a tank body with an interior that can be easily accessed for cleaning and repair purposes by removing upper and lower end plates securely and sealing fitted by gaskets to the upper and lower ends of the tank. The interior is connected to a liquid source for supplying liquid, a gas source for carbonating the liquid, and drawing means for dispensing carbonated liquid from the interior of the tank. |
| US10988361B2 |
Visual assistance to the on-ground movement of a lifting platform
The aerial work platform comprises a control console (30) for moving the platform (20) to a working position at a height and for moving the chassis (2) on the ground in the forward (FAV) and backward (FAV) directions. To avoid confusing these two directions of movement because of the variable orientation of the console (30) with respect to the chassis (2), the direction of movement selected at the control console (30) is indicated to the operator by activation of at least one visual indication (63a, 64a, 64b, 70.i, 72) located on the side of the chassis (2) that corresponds to the direction of movement selected, or having a form pointing in the direction of movement (FAV, FAR) selected. A screen (40) also indicates the direction of movement (FAV, FAR) selected by a display transposing to the screen (40) the above visual indication system in relation to the azimuthal direction of the chassis (2) with respect to the console (30). |
| US10988359B2 |
Overhead transport vehicle and transport system
An overhead transport vehicle includes a traveling body that travels on a track on a ceiling of a facility, an upper mast attached to a lower side of the traveling body and including an upper guide, an elevation platform on which an article is placed, and which is guided by the upper guide to ascend or descend along the upper mast, and a lift driver that is provided on the traveling body or on the elevation platform and that drives the elevation platform to ascend or descend. A lower mast is connected to the lower end of the upper mast via a connector in a freely detachable manner and includes a lower guide extending to the upper guide. The elevation platform is able to be lowered along the lower mast from the upper mast by the lift driver. |
| US10988353B1 |
Power winch equipment crane with hinge members
A power winch equipment crane system to be used with a tractor roll bar, the system including a winch support bar configured to be generally U-shaped having two side portions and a middle portion connecting the two side portions, a power winch attached to the winch support bar proximate a midpoint of the middle portion of the winch support bar, and hinge members provided respectively proximate each end of the winch support bar and configured to couple the winch support bar to the tractor roll bar in a pivoting arrangement, the hinge members configured such that the winch support bar is pivotable between a substantially vertical position when not in use, and a substantially horizontal position in which the power winch is positioned at a point spaced back from the tractor so as to be located over an implement that is attachable to the tractor. |
| US10988352B2 |
Crane support assembly
A crane support system includes two spaced apart longitudinal members couplable with a vehicle frame. Two spaced apart groups of tubes are coupled with and extend between the longitudinal members and outboard relative to one member to define an outboard subassembly portion. A tower frame is mounted atop the outboard subassembly portion. A first brace extends angularly between the groups of tubes, the brace extending from a one of the groups forward relative to the vehicle frame toward the other group aft relative to the vehicle frame and toward the tower frame. A horizontal arm extends transversely beneath the outboard subassembly portion. A vertical support has a top end coupled with the arm and a bottom end couplable with an outrigger. A second brace extends angularly between the vertical support and the arm for transferring bending moment and/or shear from the cantilever to the outrigger via the vertical support. |
| US10988349B2 |
Anchor point with movable tilt axis
An anchor point (1) for e.g. lifting and/or lashing down an object (2) includes a base (4), which is configured for fixing to the object (2) such that it is rotatable about an axis of rotation (7). The anchor point (1) also includes a retainer bracket (3) held on two bearing points (5) on the base (4) such that it is tiltable about a tilt axis (11) relative to the base (4). In order to prevent the retainer bracket (3) from getting stuck when a force is applied thereto, which may lead to a sudden and jerky turnover of the retainer bracket or even to fracturing of the anchor point (1) and crashing of the load, the tilt axis (11) is movable relative to the base (4). Preferably, a motion link (25), for example, is provided on at least one bearing point (5). |
| US10988339B2 |
Drywall banjo tools for applying joint tape
Method and apparatus are disclosed for drywall banjo tools for applying joint tape. An example drywall banjo for applying joint tape includes a banjo body. The banjo body includes a panel and side walls protruding from outer edges of the panel to define a cavity that is configured to contain joint compound mud. The side walls include a first side wall that extends between an inlet and an outlet. The example disclosed drywall banjo also includes a sloped mound configured to couple to and project away from the first side wall within the cavity. The sloped mound is configured to guide the joint compound mud within the cavity toward the joint tape travelling between the inlet and the outlet to enable the joint compound mud to uniformly collect on a side of the joint tape. |
| US10988338B2 |
Brake assembly for a tape dispenser
A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously. |
| US10988330B2 |
Media size detector
In one example, a media size detector includes a button coupled to a spring of a housing to interact with a media size adjuster of a media tray, a first side of a lever to receive pressure from the spring when the button is depressed by the media size adjuster, and a second side of the lever to apply pressure to activate or deactivate a switch coupled to a printed circuit assembly when the first side of the lever receives pressure from the spring. |
| US10988326B2 |
Load assist system
The present disclosure relates to a load assist module for transferring articles onto a downstream conveyor. The load assist module may include a roller conveyor having one or more rollers that together define a conveyor plane, such that the one or more rollers may be actuatable to convey the article along the conveyor plane in a direction of a downstream conveyor. The load assist module may further include a pusher assembly positioned adjacent the conveyor plane. The pusher assembly may include a track-guided vertical popup with a base and a pop-up. The pop-up may be actuatable such that the pop-up extends through the conveyor plane to contact the article. The pusher assembly may drive the track-guided vertical popup toward the direction of the downstream conveyor such that the track-guided vertical popup pushes the article. |
| US10988321B2 |
Transport device comprising carriages guided such that they can move on a rail
The present invention relates to a transport device for transporting objects along a transport track having a rail defining the transport track; at least one slide that is travelably guided at the rail; a coupling element which is provided at the slide and via which the slide can be driven; a first drive unit having a first drive means for driving the slid along a first transport section of the transport track; and a second drive having a second drive means for driving the slide along a second transport section of the transport track. The coupling element is configured to be in engagement in a shape fitting manner with the first drive means and to be in engagement in a force-fitting manner with the second drive means in the region of the second transport section. |
| US10988320B2 |
Screw transport apparatus for bottles and bottling system provided with such an apparatus
The present invention relates to a screw transport apparatus for bottles, comprising: —a support structure, which extends longitudinally between a bottle inlet 1a and a bottle outlet 1b of the apparatus, and—a spiral-shaped helical body, which is associated with the support structure and extends axially parallel to the support structure between two own axial ends. The above spiral-shaped helical body can be rotated on itself about its own longitudinal axis to move bottles in cooperation with the support structure. The spiral-shaped helical body comprises at least two spiral-shaped seats, which extend coaxially between the two axial ends. They are angularly offset from each other and differ from each other by the shape and/or dimensions of the relative bottle housing compartment defined by each of them. The two spiral-shaped seats are intended to be used alternatively to the other for the transport of bottles having different shapes and/or dimensions. |
| US10988317B2 |
Format part for deflecting containers
A format part for deflecting containers, comprising a toggle lever which comprises a toggle joint and two ankle joints, wherein the format part comprises a railing fastened to the toggle joint of the toggle lever, wherein the ankle joints are displaceable in one plane, which is parallel to the running direction of the railing, and wherein the railing is displaceable parallel to said plane by the displacement of the ankle joints, wherein the format part is adaptable for different container formats by the displacement of the railing, accumulating conveyor comprising such a format part, and method for adjusting such a format part. |
| US10988316B2 |
Holder transport apparatus
A holder transport apparatus according to an embodiment includes, an elevator device comprising a conveyance member which includes an ascending path and a descending path arranged along an ascending and descending circulation path that circulates, and a plurality of support plates which are attached to the conveyance member and support a holder which holds a sample container in an erect state. |
| US10988315B1 |
Item stabilizer
A stabilizer can include an attachment surface and a non-stick surface. Multiple stabilizers can be arranged in a stack, e.g., such that the attachment surface of one stabilizer is engaged with the non-stick surface of another stabilizer. A stabilizer can be removed from the stack and attached to an item having a curved surface along the length of the item. The item, with the stabilizer attached, can be positioned on a conveyance surface, e.g., such that the stabilizer is between the conveyance surface and the item. |
| US10988314B2 |
Drive system for conveyors
A conveyor system includes a drive assembly and a plurality of rollers configured to singulate a plurality of conveyed articles travelling on the plurality of rollers along a direction of travel. Each of the plurality of rollers having a drive end and a base end. The drive end having a drive sheave including a plurality of grooves and a plurality of peaks interposed between the plurality of grooves formed on a surface thereof. The drive assembly is coupled to the drive end of at least one of the plurality of rollers by a drive belt. At least a first portion of the plurality of rollers is disposed at an angle with respect to the direction of travel. |
| US10988313B2 |
Fulfillment system, article and method of operating same
Fulfillment systems may include an item storage and retrieval system which stores and automatically retrieves items, and an order sorting system, downstream from the item storage and retrieval system, which automatically collates retrieved items into orders. A control system controls operation, advantageously allowing operation without any item buffering buffer between the item storage and retrieval system and the order sorting system. Optionally, a destination sortation system may collate orders by intended destinations. The fulfillment system can handle orders for end user consumer as well as for retail locations simultaneously. Robots and/or conveyors may operate to move items between the systems. |
| US10988307B2 |
Disposable capsule for dispensing machines of infused beverages
A disposable capsule for use in beverage machines is disclosed. The capsule has a hollow, cup-shaped body adapted to receive a measured dose of a syrup, a liquid or a powder concentrate. The hollow body has an insert housed therein which includes a disc-shaped portion and a stem which stretches out axially from the top of the disc-shaped portion. The stem has an axial through cavity which defines a channel for the dispensing of a beverage. The through cavity includes an inlet formed at an end of the stem located close to the cover of the capsule and an outlet formed at the opposite end of the stem. |
| US10988305B2 |
Powder feeding apparatus and method thereof
A powder feeding apparatus drops powder from a tank storing the powder to an oblique portion, and accumulates the powder on a plate disposed below the oblique portion. The plate is provided with a flat surface portion and a groove portion which is inverted from the flat surface portion to a lower part. The scraper moves powder which has accumulated to a higher level than a constant height on the flat portion and the groove portion, to an outer-side of the flat portion and smoothes the powder on the flat portion and the groove portion to a constant height. An ejector takes in powder which has accumulated on the groove portion of the plate by a suction opening, disposed at a front side of the scraper, in a relative moving direction of the plate, and discharges the powder from the discharge opening. |
| US10988298B2 |
Container assembly for flowable materials
A container assembly for flowable materials, the container assembly comprising: a reusable outer supporting container; and a disposable inner plastic liner; wherein the reusable outer supporting container comprises an outlet pipe comprising a first outlet pipe section connected to the reusable outer supporting container and a second outlet pipe section releasably connectable to the first outlet pipe section, wherein the second outlet pipe section comprises a valve for selectively closing off the second outlet pipe section, and wherein at least one of the first outlet pipe section and the second outlet pipe section comprises an annular recess; and wherein the disposable inner plastic liner comprises a tubular outlet portion, wherein the tubular outlet portion comprises an outer flange configured to be captured between the first outlet pipe section and the second outlet pipe section, and further wherein the outer flange of the tubular outlet portion comprises an annular protrusion configured to be received in the annular recess when the outer flange is captured between the first outlet pipe section and the second outlet pipe section. |
| US10988296B2 |
Barrier spout
A barrier spout is comprised of a straw and a sealboat. The straw comprises a body having a first straw portion and a second straw portion, with an upper opening of the straw at a first end of the first straw portion and a lower opening of the straw at a second end of the second straw portion, the first straw portion and the second straw portion meeting at a second end of the first straw portion and a first end of the second straw portion. The straw is comprised of a barrier material to minimize at least one of oxygen and vapor transmission through the barrier material. The sealboat comprises a sealing material, the sealboat contacting an inner surface of the sealboat forming a liquid seal between the straw and the sealboat. |
| US10988292B2 |
Tamper-evident closures
A tamper-evident closure includes a cap having a plug, a skirt, and a locking member. The cap and skirt have seats in which a first portion and a second portion of the locking member are arranged. Upon first opening, as the cap moves longitudinally away from the skirt, the lower edge of the cap passes over the first portion longitudinally so that, upon reclosing the tamper-evident closure, the first portion positions in an obstructive manner between the lower edge of the cap and an upper edge of the skirt. |
| US10988291B2 |
Travel bottle having a twisting locking ring body
A bottle includes a secure sealing mechanism. A bottle cap screwed onto a bottle maintains the contents of the bottle. This is achieved by securing a dispensing mechanism in a closed, locked position and sealing an outlet so that any liquids being forced into a dispensing passageway are prevented from passing through the passageway. |
| US10988289B2 |
Child-resistant closure device for a container having a tapered neck portion
A child-resistant closure device for a rigid plastic container having a tapered neck section and method of manufacture. The device has a substantially circular neck and inner lid surface. The neck includes anchors which engage with nodes on the inner lid surface. The tapered section of the neck acts as a spring engaging the nodes with the anchors. The closure device may be engaged by rotating the lid in relation to the neck. To disengage the closure device a simultaneous downward and rotational force must be applied. The lid and the container, including the closure, can be blow molded at the same time or separately. |
| US10988284B2 |
Vial sleeve assembly
A sleeve for securing a cryogenic vial includes a cylindrical body sized to receive a vial, the body including a longitudinal axis, a first end, and a second end. A plurality of deformable members are disposed near the first end of the body and are arranged to deform from a first configuration to a second configuration. Each deformable member is displaced outwardly relative to the longitudinal axis of the body in the second configuration. |
| US10988283B2 |
Case for coin tissue
A case for coin tissue is disclosed. In one aspect, the case includes a drawer housing including an insertion space and a push-in and pull-out portion communicating with the insertion space. The case also includes a drawer configured to be pushed into or pulled out of the insertion space in a slidable manner through the push-in and pull-out portion. The drawer includes an upper opening portion. A plurality of coin tissues are placed in one or more rows in the drawer. The case further includes a pull-out distance limiting part provided between an inner surface of the drawer housing and an outer surface of the drawer, and configured to limit a pull-out distance of the drawer to a first distance. According to at least some embodiments, the case for coin tissue can sanitarily preserve a coin tissue, and is portable, and convenient. |
| US10988282B2 |
Container
A container includes a base, a folding sleeve and a lid. The sleeve includes several panels configured to be folded and laid out on the base such that the panels extend approximately parallel to the base, and to be unfolded and placed on the base such that the panels extend approximately perpendicular to the base, bearing through lower edges of the panels on the base, the lid being capable of bearing on top edges of the panels when the sleeve is unfolded and placed on the base. The container includes at least one band of flexible material that is fixed to the lid at at least two distant points, and that passes through an orifice in at least one of the panels, the lid configured to be guided by the at least one band when the container is opened, by sliding of the band in the orifice over at least part of the length of the band between said two points. |
| US10988280B2 |
Secondary insertion feature for assembled package
The present exemplary system and method relates to a feature upon the exterior of a corrugated package that allows an access secondary to the primary opening feature for the inclusion of sample materials that are added after the package has been sealed at the contents' (e.g., appliance) place of manufacture. The benefits of the invention are reduced unit operations and labor to include sample materials. Additionally, the packaging feature will deter theft of sample materials from the product to the point of sale. The theft deterrence is achieved via a tamper-evident label covering the feature after sample materials have been inserted. |
| US10988279B2 |
Package maker
An apparatus for forming a box or bag that is made of a substrate strip which includes a winder having a mandrel and posts that extend from the mandrel in a direction parallel to a winding and translation axis that rotate together as a unit around the translation axis. The apparatus also has a feeder that includes precursors and a gathering head used for forming the precursors into the strip and feeding the strip to the winder. A motor adjusts the feeder's angle relative to the winder in response to instructions from the controller based on the dimensions of the box or bag. This causes controlled overlap between adjacent windings of the strip on the posts. As the mandrel rotates, the posts draw the strip and wind the strip along a spiral having a length in excess of the depth. Zero waste of precursors is made possible by cutting the substrate perpendicular to its length and folding over the box or bag ends to form an angled seam with respect to the sides of the box. |
| US10988276B2 |
Machine and method for its operation
A labelling machine comprises a supply spool support for supporting a supply spool comprising label stock comprising a web and a plurality of labels attached to the web and which are separable from the web; a take-up spool support adapted to take up a portion of web; a motive means configured to propel the web along a web path from the supply spool support towards the take up spool support. A sensor has a transmitter portion and a receiver portion, the receiver portion comprising a plurality of receivers, the transmitter portion and receiver portion are configured to receive a portion of the label stock therebetween, and the plurality of receivers are each configured to produce a respective sensor signal which is a function of a property of a portion of label stock at a plurality of positions spaced from one another in a direction non-parallel to the web path. In addition, a controller is configured to monitor each of the sensor signals produced by the receivers and to select one of the sensor signals produced by the receivers based on said monitoring of each of the sensor signals produced by the receivers. |
| US10988273B2 |
Vacuum packaging machine
Provided is a vacuum packaging machine (100), comprising a machine body (1), a vacuum cover (2), a main controller (3), a sub-controller (4), a heat-sealing mechanism (5) and a vacuumizing mechanism (6), wherein a vacuum chamber (11) is provided in the machine body, the vacuum cover covers the machine body and corresponds to the position of the vacuum chamber; the main controller is provided on the machine body, the sub-controller is provided on the vacuum cover, and the main controller is in communication connection with the sub-controller; and the main controller is in communication connection with the heat-sealing mechanism and the vacuumizing mechanism, and functional keys (40) used for implementing vacuumizing and heat-sealing operations are provided on the sub-controller. |
| US10988272B2 |
Packaging machine
A packaging machine includes a vertical sealing unit, a movable cover, and a linkage mechanism. The vertical sealing unit is provided so as to be retractable from a vertical sealing position for tubular film. The movable cover covers a heated part of the vertical sealing unit. The linkage mechanism transmits a retracting movement of the vertical sealing unit to the cover to thereby cause the cover to move from a position in which it exposes the heated part to a position in which it covers the heated part. |
| US10988271B2 |
Vacuum packaging method and vacuum packaging apparatus
The invention provides a vacuum packaging method and a vacuum packaging apparatus that can sufficiently degasify the inside of a packaging bag without any trouble and in which bubbles are less likely to remain inside the packaging bag after vacuum packaging, even if a liquid is included in a packaged object. |
| US10988270B2 |
Packaging apparatus and system to fill single-serve pods
An apparatus and packaging system for filling single-serve pods is described. The apparatus includes a base for supporting a rotatable platform comprising multiple pod holders, a filler mounted on the base and adjacent to the rotatable platform comprising a container filled with food product and multiple augers capable of filling the pods with food product, a sealer mounted on the base comprising a film winder, and a controller directing rotation of the rotatable platform, filling of the food product from the filler, and sealing and trimming of the sealed film tops of the single-serve pods. |
| US10988268B2 |
System and method for performing operations on an engine
A system is provided for performing an operation on a component of an engine. The component includes a first side positioned within an interior of the engine. The system includes a first robotic arm defining a first distal end and including a first utility member positioned at the first distal end, the first robotic arm moveable to the interior of the engine to a location operably adjacent to the first side of the component; and a second robotic arm defining a second distal end and including a second utility member positioned at the second distal end, the second robotic arm also moveable to the interior of the engine to facilitate the first and second utility members performing the operation on the component of the engine. |
| US10988267B2 |
Drone camera handles
Devices and methods improving the ability to manually photograph or record video footage with a camera drone. Handles couple the drone and enhance the ability to balance and manually orient the drone camera. A mounting mechanism permits attachment and hands-free viewing of image data transmitted from the drone camera. Improved ergonomics allow better control of image content and decrease the risk of damage due to dropping or direct handling of the drone. |
| US10988266B2 |
Aircraft auxiliary power unit (APU) control system having speed compensation
An auxiliary power unit (APU) control system for an aircraft is disclosed. The APU control system includes an APU, one or more processors, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the APU control system to receive a one or more ambient signals indicative of an air density value and one or more power signals indicative of a specific amount of power generated by the APU. The APU control system is further caused to determine a variable rotational speed of the APU based on the air density value and instruct the APU to operate at the variable rotational speed. The APU continues to generate the specific amount of power when operating at the variable rotational speed. |
| US10988264B2 |
Lightweight primary structure for aircraft engine mounting pylon
In order to reduce the mass of a primary structure of a mounting pylon for an engine of an aircraft, the mounting pylon includes a box and a rear sub-structure fastened to the box which includes two lateral panels, each equipped at its rear end with a first linking portion through which passes a first connection orifice that is designed to receive a connection pin of a lateral front wing attachment. The rear sub-structure is made in one piece and includes two opposite lateral flanks that are respectively fastened to the two lateral panels of the box by fastening elements. Each lateral flank has a second linking portion through which passes a second connection orifice that is aligned with the first connection orifice, and is also designed to receive the connection pin of the lateral front wing attachment. |
| US10988263B2 |
VTOL aircraft with jet engine coupled to downward thrust nozzles
An aircraft including an engine compartment and an engine provided in the engine compartment. The aircraft further includes a ductwork housing positioned above the engine. The ductwork housing includes at least one duct. The at least one duct has an outlet port that faces downwardly. Operation of the engine causes air to flow through the duct and exit the outlet port. The outlet port is configured to direct the air flow downwardly to provide lift for the aircraft. |
| US10988258B2 |
Cargo restraint sensor system
A cargo restraint system and associated methods may include sensing assemblies associated with cargo latches in a cargo hold of an aircraft. In some embodiments, the sensing assemblies include sensors configured to sense information relating to the cargo latches, wireless communication circuits configured to transmit the sensed information to a central controller, and batteries powering the wireless communication circuits. A wireless power transmission system may be configured to wirelessly broadcast power to the sensor assemblies to charge the batteries. In some embodiments, the cargo latches are transitionable between an extended configuration for cargo restraint and a retracted configuration for cargo loading and unloading, and the sensors are configured to sense whether the cargo latches are in the extended configuration. |
| US10988257B2 |
Aircraft-retrieval system
The present disclosure provides various embodiments of an aircraft retrieval system including winch-equipped retrieval assembly that is removably attachable to a rotorcraft to facilitate retrieval of a fixed-wing aircraft from wing-borne flight. |
| US10988249B1 |
Tilting mechanism with telescoping actuator
A tiltrotor has a range of motion between a forward flight position and a hovering position, where a pylon and the tiltrotor are coupled via a telescoping actuator, a rigid bottom bar, and a fixed hinge that is attached between the rigid bottom bar and the tiltrotor. The tiltrotor moves from the forward flight position to the hovering position includes extending the telescoping actuator so that the tilt rotor rotates about the fixed hinge. |
| US10988248B2 |
VTOL aircraft
The aircraft can include: an airframe, a tilt mechanism, a payload housing, and can optionally include an impact attenuator, a set of ground support members (e.g., struts), a set of power sources, and a set of control elements. The airframe can include: a set of rotors and a set of support members. |
| US10988247B2 |
Unmanned aerial vehicle and propulsion system for an unmanned aerial vehicle
An unmanned aerial vehicle includes a propulsion system having at least one propulsion module comprised of at least one propeller and at least two motors/engines, one or more of the motors/engines providing mechanical energy to drive the propeller, wherein the difference between the angular velocities of the motors/engines provides energy input to a mechanical or magneto-mechanical linkage system to change the blade pitch angle of the propeller, in cyclic and/or collective manner. |
| US10988245B2 |
Segmented duct for tilting proprotors
A tiltrotor assembly has a central hub with a plurality of rotor blades extending therefrom and is configured to rotate about a mast axis to generate lift in a hover position. The central hub is configured to rotate about a tilt axis between the hover position and a forward-flight position such that rotation about the mast axis generates forward thrust. The central hub is surrounded by a segmented duct that includes a thin rotatable inner ring and a wide fixed outer ring. The inner ring is configured to rotate with the central hub about the tilt axis leaving the wide outer ring in a generally horizontal position. |
| US10988244B2 |
Helicopter rotor hub assembly and helicopter including same
A helicopter rotor hub assembly for coupling a pair of helicopter blades to a helicopter mast. It includes a yoke assembly and a pitch assembly. The yoke assembly includes a central section and first and second sections extending respectively on opposite sides of the central section. Each one of the first and second sections has a pair of elongated arms defining inbetween a bearing-receiving interspace. The pitch assembly includes first and second attachment plates extending respectively along the first and second sections of the yoke assembly and first and second pitch bearing assemblies. Each attachment plate is connected to a respective one of the helicopter blades. Each pitch bearing assembly extends in the bearing-receiving interspace of a respective one of the first and second sections of the yoke assembly. Each pitch bearing assembly contacts a respective one of attachment plates to allow a pitch movement of the helicopter blades. |
| US10988242B2 |
Rotor assembly and unmanned aerial vehicle having the same
A rotor assembly includes a motor, a propeller, and a connection assembly. The motor includes a stator and a rotator rotatable with respect to the stator. The connection assembly includes a locking member provided between the propeller and the rotator. The locking member is configured to rotate with respect to the rotator and the propeller to lock the propeller to the motor. |
| US10988237B1 |
Feed forward equalization control for active-active redundant actuation systems
A method and apparatus for controlling movement of a component in a system by a plurality of actuators. An operation actuation command to move the component is received. For each of the plurality of actuators, the operation actuation command is used to generate a feed-forward equalization command for the actuator, the feed-forward equalization command for the actuator is combined with the operation actuation command to provide an equalized actuation command for the actuator, and the actuator is controlled to move the component using the equalized actuation command for the actuator. |
| US10988234B2 |
Aircraft having hydraulic support struts between fuselage and wings
An aircraft with a fuselage and with wings connected thereto, wherein a support strut extends between the fuselage and each of the wings, which support strut is connected both to the fuselage and to the wing. The support strut has a hydraulic working cylinder, which can be pressurized with hydraulic fluid in a controlled manner for the purpose of pivoting the wing. |
| US10988233B2 |
Wing and aircraft
[Object] To provide a wing achieving reduction of friction drag and easy to design and also easy to manufacture and an aircraft including such a wing.[Solving Means] A wing 1 is typically used as a main wing of an aircraft 100. The wing 1 is a swept-back wing having a swept-back angle A. The wing 1 is configured such that a surface pressure (pressure distribution (Cp)) on an upper surface of a vicinity of a leading edge 11 in a fluid increases from a wing root 17 to a wing tip 15. A cross-flow component of an external streamline of a surface of the wing 1 is reduced in the vicinity of the leading edge 11, and boundary layer transition is not easily induced in the vicinity of the leading edge 11. With this, friction drag caused by cross-flow instability can be reduced. |
| US10988231B2 |
Space frame fuselage with pressure membrane
Disclosed are structures and features of a space frame aircraft. In particular, this disclosure relates to a space frame aircraft with a pressure membrane. |
| US10988229B2 |
Solid laminate stringer
A solid laminate stringer includes a base segment that forms a first generally trapezoidal cross section. The solid laminate stringer also includes a transition segment abutting the base segment, with concave sides that are continuous with the sides of the base segment. The solid laminate stringer also includes a top segment abutting the transition segment, where the top segment forms a second generally trapezoidal cross section with sides that are continuous with the concave sides of the transition segment. The solid laminate stringer may also include a first overwrap layer covering the top segment, the transition segment, and at least a portion of the base segment. The solid laminate stringer may also include a second overwrap layer overlapping at least a portion of the first overwrap layer covering the base segment. |
| US10988227B2 |
High altitude balloon systems and methods using continuous multi-compartment super pressure balloon
Features for a high altitude lighter-than-air (LTA) system and associated methods. A zero-pressure balloon (ZPB) is attached in tandem with one or more variable ballast air super-pressure balloons (SPB) having a continuous skin and multiple SPB compartments. The ZPB provides lift for the system while the multi-compartment SPB uses a centrifugal compressor to provide a variable amount of ballast air by pumping in or expelling out ambient air. Various performance targets relating to ascent rate, descent rate, range and maximum altitude are achievable with various scaled versions of the basic design of the LTA system. Navigation and control techniques, such as high altitude station-keeping approaches, are made possible with the LTA system. |
| US10988226B2 |
Methods and apparatus for constructing airships
Systems, apparatuses, and methods for constructing an airship quickly and cost-effectively are described. In one embodiments, an airship structure may have a plurality of mainframes, each comprising interconnected pyramid structures. One of the pyramid structures may include an apex joint, four base joints, first connectors, and second connectors. The apex joint and base joints may each have slots configured for receiving connectors. The apex joint may have four apex-to-base slots and each base joint may have a base-to-apex slot and two base-to-base slots. Each of the first connectors may connect the apex joint to one of the four base joints using one of the apex-to-base slots of the apex joint and the base-to-apex slot of that base joint. Each of the second connectors may connect two of the four base joints using one of the base-to-base slots of each of the two base joints connected by that second connector. |
| US10988225B2 |
Flying object with multi-purpose landing gear module
A flying object with a landing gear module serving as a floating weight that can be used simultaneously with an airship and an aerial mooring type aerostat, and more particularly, a flying object capable of simultaneously allowing a landing gear to serve as a floating weight, thereby stably simplifying a mooring process of the flying object and manufacturing the flying object at low cost. |
| US10988222B1 |
Outboard motors and tie bar apparatuses for coupling an outboard motor to an adjacent outboard motor
An outboard motor has a powerhead; a supporting cradle supporting the powerhead, the supporting cradle having port and starboard sides extending alongside opposite sides of the outboard motor; a resilient mount coupling the powerhead to the supporting cradle and being configured to absorb vibrations of the powerhead; and a tie bar mounting bracket having a head portion located aftwardly of the supporting cradle and further having port and starboard arms extending forwardly from the head portion alongside the opposite sides of the outboard motor and being coupled to the port and starboard sides of the supporting cradle, respectively. A cooling system conveys cooling water through the outboard motor and has a telltale outlet that discharges cooling water through the tie bar mounting apparatus. |
| US10988221B2 |
Control device for power kites
Disclosed is a control device for power kites. It consists of a tall Y-shaped structure, the base of which is connected to the center of a horizontal control bar arranged perpendicular to the structure. An articulation forms the connection between the base of the structure and the center of the horizontal control bar. The control lines for the leading edge and the control lines for the trailing edge of a power kite are attached to the front and rear pre-lines of the device. Compared to a standard kite bar, the disclosed control device makes it easier for the user to balance using very short lines. |
| US10988219B1 |
System and apparatus for integrated pressure compensator
Systems and methods are disclosed herein for a pressure tolerant energy system. According to one aspect, an underwater vehicle may comprise one or more buoyancy elements, a pressure tolerant cavity, and an energy system enclosed in the pressure tolerant cavity configured to provide electrical power to the vehicle. The energy system may include one or more neutrally buoyant battery cells. In some aspects, the battery cells may have an average density that is about equal to the density of the fluid in which the vehicle is immersed. The vehicle may also comprise a pressure tolerant, programmable management circuit. |
| US10988218B2 |
Remotely operated underwater vehicle and control method therefor
The present disclosure relates to a remotely operated underwater vehicle and a control method therefor. The remotely operated underwater vehicle comprises a body having an imaging unit and a control unit; a power unit disposed on the body; a beacon unit for being worn on a part of a user's body, wherein the beacon unit can emit a plurality of optical control signals with different brightness; and the control unit can control the power unit to respond according to the optical control signals collected by the imaging unit to adjust an action and a posture of the body. |
| US10988214B1 |
Offshore transfer and destruction of volatile organic compounds
A vapor taker system, a vessel-based solution to accommodate vapor destruction during hydrocarbon loading and/or lightering, is disclosed. The vapor taker has vapor destruction equipment, support fuel, and accommodation for loading hose connections as necessary to comply with air emissions requirements for the destruction of volatile organic compounds. The vapor taker system can be modular or fully integrated into a marine vessel such as a ship, barge, tanker, and so forth. |
| US10988211B2 |
Mooring system for drifting energy converters
A system that maintains the relative and/or absolute geographical positions of two or more buoyant devices floating in a body of water. A plurality of formation restoring tethers are disclosed which permit the unrestricted vertical movement of networked buoyant devices, while resisting increases in their lateral separations by providing restoring forces to oppose such separations. Tensioning mechanisms incorporated into the tethers generate the resistance to the lateral separations of two or more entities by transforming such separations into an increase in the potential energy stored within such tensioning mechanisms, the potential energy of which is released in the process of restoring the original separations and/or positions of the displaced buoyant devices. |
| US10988210B2 |
Hybrid chine boat hull and methods of manufacture and use
This disclosure describes hybrid chine hulls, marine vessels including hybrid chine hulls and methods of manufacturing and using hybrid chine hulls. An exemplary hybrid chine hull includes a keel, a single chine section, and a double chine section distinct from the single chine section with respect to a longitudinal direction of the keel and positioned aft of the single chine section. |
| US10988209B1 |
Bicycle control system
A bicycle control system includes a housing having an upper mounting surface and housing a brake actuation system. A lever is pivotally coupled to the housing about an axis and is operably coupled to the brake actuation system. An electronic module includes a housing releasably coupled to the upper mounting surface. The housing sealingly encloses at least one electronic component. The lever may be pivotally coupled to the housing about both a shift axis and a brake axis, wherein the shift axis and the brake axis being non-orthogonal. A bicycle control kit includes different first and second electronic modules. |
| US10988208B2 |
Control device and transmission system
A control device includes an electronic controller configured to control a transmission device of a human-powered vehicle in accordance with a shifting condition. The electronic controller is configured to change the shifting condition in accordance with a converging state of a first reference value that changes as the human-powered vehicle travels. |
| US10988206B1 |
Assistance system for facilitating operation of electric cycle
An assistance system includes a resistance detecting unit obtaining a resistance factor, a database storing starting torque values and operating torque values, a torque calculation unit including a controller, and a torque-control handlebar grip operated to trigger an assigned gain and to tune the same to be provided to the torque calculation unit. When switched to an aided mode, the controller calculates a compensated torque value based on one of the starting/operating torque values and the resistance factor, calculates an output torque value by a product of the compensated torque value, the assist ratio and the assigned gain, and controls a torque motor to drive rotation of a driving wheel based on the output torque value. |
| US10988201B2 |
Motorcycle
A motorcycle comprises a vehicle body frame including a head pipe part, a pair of right and left main frame parts extending rearward from the head pipe part while being inclined in a downward direction, a down frame part extending downward from the head pipe part to a location that is below the main frame parts, and a bridge frame part coupling the main frame parts to the down frame part; a fuel tank supported by the main frame parts; and a canister connected to the fuel tank via an inlet tube and configured to store therein evaporated fuel generated in the fuel tank. The canister is disposed on a first side in a vehicle width direction. In a side view, the canister is disposed in a region surrounded by the main frame part, the down frame part, and the bridge frame part. |
| US10988183B2 |
Locking device for a buttress of a flying buttress hood
A locking device for a buttress of a flying buttress hood of a vehicle, having a locking element for locking the buttress in a locking position and a display device for visually signaling the locking position. The display device has a display element which is coupled via a coupling element to the locking element and therefore a movement of the locking element into the locking position moves the display element via the coupling element into a first display position and, upon leaving the locking position, the locking element via the coupling element moves the display element from the first display position into at least one second display position. |
| US10988173B2 |
Method and device for operating a transportation vehicle function
A method for operating a transportation vehicle function based on a natural frequency and/or a moment of inertia of a steering wheel arrangement in a steering system including prespecifying an electromotive steering intervention to move the steering system by providing a steering intervention force or a steering intervention torque; ascertaining a natural frequency and/or a moment of inertia of the steering wheel arrangement depending on the response of the steering wheel arrangement based on the electromotive steering intervention; and operating the transportation vehicle function based on the ascertained natural frequency and/or the ascertained moment of inertia of the steering wheel arrangement. |
| US10988172B2 |
External damping of power steering for a vehicle
A steering member has a rack portion and a screw portion. The steering member is in a steering housing and operatively connected to a tie rod. A pinion is operatively connected between the rack portion and a steering wheel. A ball nut is operatively connected to the screw portion. A power source is operatively connected to the ball nut. The power source drives the ball nut to effect linear movement of the steering member upon rotation of the steering wheel. A damper has a first connection to the tie rod and a second connection to a ground surface. The ground surface is fixed relative to the steering member. The damper is external to the ball nut. |
| US10988167B2 |
Power steering apparatus
A power steering apparatus includes a steering shaft 10 including an input shaft 11, an intermediate shaft 13 connected through a first torsion bar 12 to the input shaft, and an output shaft 15 connected through a second torsion bar 14 to the intermediate shaft; a hollow motor 30 to provide a rotational force to the intermediate shaft; and a control device 60 including a microcomputer, and including an output shaft rotation angle presuming section 63 to presume an output shaft rotation angle θg based on signals of an input shaft rotation angle θh and an intermediate shaft rotation angle θm, a torsion spring constant g1 and g2 of the first and second torsion bars; and a motor drive control section 69 to control the hollow motor based on the output shaft rotation angle. |
| US10988166B2 |
System and method for adapting steering torque based on a motor vehicle present driving situation
A method for generating an auxiliary steering torque (AST) adapted to a present driving situation (PDS) of a motor vehicle using an active steering assistance system (SAS), including ascertaining the present driving situation (PDS); classifying the ascertained present driving situation (PDS) into at least one of a group of driving situation categories (DSC); and generating an auxiliary steering torque (AST) using the active steering assistance system (SAS). Wherein the amount and/or a time profile of the auxiliary steering torque (AST) depends on the classification of the present driving situation (PDS) into one of the driving situation categories (DSC). |
| US10988161B2 |
Steering input system for a vehicle
A steering input system for a vehicle, the system including: a steering input device configured to provide a steering action input for the vehicle, and an actuator assembly including a set of actuators configured to translate the steering input device from a drive position to a retracted position by a combined actuation action. |
| US10988159B2 |
Drive mechanism and automatic swing device including the same
A drive mechanism which is adapted for use with a swing device includes two symmetrically-disposed electromagnetic driving units and a control unit. The electromagnetic driving units are adapted to be pivotally connected to a bottom of the swing device. The control unit is electrically connected to the electromagnetic driving units for controlling the electromagnetic driving units to be alternately activated and deactivated, so as to generate an intermittent magnetic force to drive swinging movement of the swing device. The swing device including the drive mechanism is also disclosed. |
| US10988158B2 |
Brake assembly for robotic surgery system
A robotic surgery cart has a pair of rear wheel assemblies and a pair of front wheel assemblies. A brake assembly for the robotic surgery cart includes a gearbox interposed between and connected to the pair of rear wheel assemblies by rotatable shafts. Elongate actuators extend between and interconnect the rotatable shafts and brake mechanisms for the front wheel assemblies. A pedal lever is rotatably coupled to the gearbox and can rotate clockwise by pressing one portion of the pedal lever and can rotate counterclockwise by pressing another portion of the pedal lever. Rotation of the pedal lever causes the gearbox to rotate the rotatable shafts to substantially lock the pair of rear wheel assemblies, and substantially simultaneously causes a translation of the elongate actuators to actuate the brake mechanisms of the front wheel assemblies, such that the wheels of the front and rear wheel assemblies brake substantially simultaneously. |
| US10988154B2 |
Powered sled
A pallet sled includes a base and a pair of tines extending from the base. A load wheel supports outer ends of each of the tines. A wheel supports the base. At least one motor is configured to drive the base wheel or at least one of the load wheels for driving the pallet sled. The motor may be a hub motor inside the base wheel or the load wheel. |
| US10988142B1 |
Determining friction coefficient of a tire/surface interface
A method for controlling a vehicle includes applying torque to a set of tires to cause the vehicle to move along a surface, reducing an amount of downward force applied to the surface by a first tire from the set of tires using an active suspension component, and actuating the first tire to control the dynamic response of the first tire relative to the surface. The method also includes determining a traction force of the first tire relative to the surface at each of multiple values for the dynamic response of the first tire relative to the surface, and determining a maximum available traction force based on the multiple values of the dynamic response and the corresponding values for the traction force. The method also includes determining a friction parameter based on the maximum available traction force, and controlling an operation of the vehicle based on the friction parameter. |
| US10988139B2 |
Vehicle position control method and device vehicle position control device for correcting position in drive-assisted vehicle
A vehicle position correction device is provided with a controller for correcting a position error of an autonomous host vehicle. The controller detects a lane boundary of a lane in which the host vehicle travels. The controller calculates a target value for a lateral correction amount of the target route by comparing positional relationships between lane boundary detection results and the target route on a map, and changes a lateral movement speed of the target route to calculate the target value for the lateral correction amount according to a bearing of the host vehicle in which the bearing being a vehicle attitude angle. The controller corrects the target route by moving the target route sideways in a lateral direction by an amount equal to the lateral correction amount upon the calculation of the lateral correction amount. |
| US10988137B2 |
Driveway maneuvers for autonomous vehicles
Aspects of the disclosure provide for controlling an autonomous vehicle to enter a driveway. As an example, an instruction to pickup or drop off a passenger at a location may be received. It may be determined that the vehicle is arriving in a lane on an opposite side of a street as the location, the lane having a traffic direction opposite to a traffic direction of a lane adjacent to the location. A difficulty score to maneuver the vehicle to the lane adjacent to the location may be determined, and the difficulty score may be compared to a predetermined difficulty score. Based on the comparison, it may be determined to an available driveway on the same side of the street as the location. The vehicle may be controlled to enter the available driveway. |
| US10988130B2 |
Model-predictive control of a powertrain system using preview information
A method for controlling continuous and discrete actuators (e.g., modes) in a powertrain system includes receiving preview information from a sensor(s) describing an upcoming dynamic state at a future time point, and providing control inputs for the actuators to a controller that includes the preview information. The input set collectively describes a future torque or speed output state at the future time point. The controller processes the input set via a dynamical predictive model, in real time, to determine control solutions to take at the present time point for implementing the dynamic state at the future time point. A lowest opportunity cost control solution is determined and optimized. The controller executes the optimized solution at the present time step. |
| US10988126B2 |
Solenoid valve assembly for a braking system for a vehicle, braking system for a vehicle, and method for mounting a solenoid valve assembly for a braking system for a vehicle
A solenoid valve apparatus for a brake system for a vehicle, including: a main valve unit; a pilot-control valve unit that is fluidically connected to the main valve unit; and a housing to accommodate at least the main valve unit and the pilot-control valve unit; in which the pilot-control valve unit includes a double solenoid unit and at least one valve device, in which the double solenoid unit is formed such that it can be populated with at least one valve device, and in which the double solenoid unit has at least two accommodating portions for accommodating valve devices and at least two solenoid devices for actuating valve devices. Also described are a related braking system and a related method for mounting a solenoid valve assembly for a braking system for a vehicle. |
| US10988123B2 |
Simulator valve and electronic brake system using the same
A simulator valve and an electronic brake system using the same are disclosed. The electronic brake system includes a master cylinder provided with at least one cylinder chamber having a volume changeable according to operation of a pedal, a pedal simulator connected to the cylinder chamber, configured to provide reaction force corresponding to a pedal effort of the pedal, a hydraulic-pressure supply device configured to provide hydraulic pressure to at least one wheel cylinder, an electronic control unit (ECU) configured to operate the hydraulic-pressure supply device, and a simulator valve provided in a flow passage through which the master cylinder is connected to the pedal simulator, and provided with a unidirectional flow passage that allows fluid to flow from the pedal simulator to the cylinder chamber and a bidirectional flow passage that is electronically opened or closed. |
| US10988119B2 |
Parking lock device for vehicle
A parking lock device for a vehicle includes a parking gear, a locking pawl, and a cam mechanism. The parking gear includes a parking lock gear that includes outer teeth that engage with a locking lug and rotates about a rotation axis, and a parking lock gear base fixed to an output shaft and allowed to rotate relative to the parking lock gear about the rotation axis. A space is provided between the parking lock gear and the parking lock gear base, such that the space expands and contracts in a circumferential direction according to relative rotation of the parking lock gear and the parking lock gear base, and an elastic body is provided in the space in a pre-compressed state. |
| US10988118B2 |
Optical sensor support plate, delivery body of a telescopic cleaning device of this optical sensor, and quick fixing device by clipping those components
In a device (100) for rapid fixing of a cleaning and/or drying fluid transporting body (6) of a telescopic cleaning device (3) on a support plate (8) for an optical sensor (2) of an optical detection system of a motor vehicle (1), the support plate (8) includes a positioning and orientating interface (12) for a first end (14) of the fluid transporting body (6) and a second locking interface (13, 13′) for a second end (15) of the fluid transporting body (6). |
| US10988115B2 |
Systems and methods for providing vehicle access using biometric data
Systems and methods providing vehicle access using identified biometric data are provided herein. An example method includes storing a first biometric input for a user in a database; receiving a ride reservation from the user, the ride reservation having at least a pickup location; activating a biometric input device associated with a vehicle when the vehicle arrives at the pickup location to obtain a second biometric input for the user; authenticating the user by comparing the first biometric input with the second biometric input; and granting access to the vehicle when the first biometric input substantially matches the second biometric input. |
| US10988111B2 |
User identification method and apparatus using lever-type door grip pattern recognition
A user identification method and apparatus using recognition of a grip pattern of a lever-type door are provided. The user identification method using recognition of a grip pattern of a lever-type door includes activating a sensing module disposed within a lever of a vehicle door when a smart-key is sensed. A grip pattern is then sensed using the sensing module and a user profile that corresponds to the grip pattern is identified. A user-customization module is activated in response to the identified user profile. |
| US10988106B2 |
Seat belt safety apparatus for vehicle
A seat belt safety apparatus for a vehicle is provided and implements both of the functions of a retractor and a pretensioner in a structure with a seat belt disposed in a seat. The functions of a retractor and a pretensioner are separated in the seat belt safety apparatus to reduce the installation space. |
| US10988105B2 |
Vehicular protection system
A vehicular protection system for protecting a protection target colliding with a vehicle is provided, which includes: a bulkhead having a bulkhead upper which extends in a vehicle widthwise direction and is arranged at an upper portion thereof; a hood arranged over the bulkhead upper; a bulkhead pop-up device configured to lift up the bulkhead upper and the hood; and a hood-moving device configured to be able to move forward the bulkhead upper and the hood. When the protection target colliding with the vehicle is protected, the bulkhead pop-up device is used to lift up the bulkhead upper and the hood and the hood-moving device is then used to move forward the bulkhead upper and the hood. |
| US10988104B2 |
Airbag aspiration modules and related valve assemblies
Airbag cushion assemblies for aspirating ambient air to enhance inflation. Some embodiments may comprise an inflation module comprising an inflator and a plurality of inflation nozzles fluidly coupled with the inflator and configured to deliver inflation gas from the inflator into an airbag cushion. A housing coupled to the airbag cushion may comprise an aspiration inlet configured to allow for receipt of ambient air into the airbag cushion during inflation of the airbag cushion. The plurality of inflation nozzles may be configured to, upon actuation of the inflator, draw ambient air into the airbag cushion along with the inflation gas from the inflator. In some embodiments, a valve assembly may be positioned below the inflation nozzles and may be configured to automatically open upon actuation of the inflator and to automatically close during or following inflation of the airbag cushion. |
| US10988101B2 |
Vehicle side airbag device
A vehicle side airbag device is stored inside a seatback of a vehicle seat and includes an airbag that inflates and deploys between a seated occupant and a side door. The interior of the airbag is partitioned into plural chambers including a high-pressure chamber, and the high-pressure chamber inflates and deploys so as to vertically straddle a door beltline as seen in vehicle lateral view and so as to restrain a shoulder region of the seated occupant. |
| US10988095B2 |
Adaptive multi-force safety system (ADMUS)
An on-board vehicle system including: an electronic computing and control unit connected to vehicle internal sensors and to a vehicle main computer, which in turn is connected to crash sensing related sensors and vehicle driving sensors, and the electronic computing and control unit is also operatively connected to an occupant weighing devices of the on-board vehicle system connected to seats of passengers which are operatively connected to inflators through controllers which are connected to electronic computing and control unit by using a method of occupant weighing, and wherein a restraint power line of an air bag of a child seat is connected to a low pressure air bag source which is connected to and controlled by the electronic computing and control unit. |
| US10988094B2 |
Textured coherent reflection component
A trim component, such as a grill of a vehicle, includes a substrate having a 3-dimensional shape and defining a disrupted reflective surface including a plurality of facets over a curved surface. Each of the facets is configured to reflect an incident light beam in a common direction, for example, toward a given target. A reflective coating, such as a chrome plating layer, overlies the disrupted reflective surface. The facets may have similar shapes and/or be arranged in a repeating pattern, but with one or more irregular features. The sizes, shapes, and/or orientation direction of the facets may varying in a gradient based on the curvature of the curved surface. The trim component also includes a light source to illuminate the disrupted reflective surface. The light source may be hidden so it is not directly visible to a viewer, but instead is reflected by the disrupted reflective surface. |
| US10988085B2 |
Motor vehicle
The present application relates to a motor vehicle comprising at least two seats and, located between these seats, a storage compartment which has a base, a front wall, a rear wall, and two side walls, wherein one or both side walls can be moved between a lowered position, laterally opening the storage compartment, and a raised position, laterally closing the storage compartment. |
| US10988079B2 |
Vehicular interior lighting device and roof module
A vehicular interior lighting device includes a main body portion fixed to an inside surface of a roof, a light source accommodated in the main body portion, a light shielding cover portion constituting a housing with the main body portion and covering the light source from below, and a light guide member having a protruding portion protruding along the inside surface from a gap between the main body portion and the cover portion. The light guide member has a diffusion portion formed on a surface of the protruding portion facing downward and diffusing light, a first light guide portion guiding light emitted from the light source to the protruding portion, and a reflecting portion reflecting light guided by the first light guide portion toward the diffusion portion. |
| US10988078B2 |
Notifying device and notifying system
A notifying device mounted in a vehicle has a controller and a light emitter. The controller determines, based on a detection result of a plurality of objects existing in a periphery of the vehicle, respective directions of notification objects included in the plurality of objects with the vehicle as a reference. The light emitter emits light in the respective directions. |
| US10988068B2 |
Shield assembly for a dump box
A shield assembly for the dump box of a vehicle includes a first plate connected to a front wall of a dump box. A second plate, having a center section and outer sections is pivotally connected to the first plate. A handle is pivotally connected to the top plate and is adapted to move the second plate to a raised and a lowered position and lock in a raised and a lowered position. |
| US10988065B2 |
Vehicle seat
A vehicle seat having a vehicle seat base comprising a generally concave seat pan (4) and side plates (16) fixed to the seat pan for mounting the seat pan to the vehicle wherein the seat pan has, all relative to the direction of movement of the vehicle, a front face, a rear face, two lateral side faces and a bottom face, and wherein the side plates extend from the front towards the rear of the seat pan and are bonded to the lateral side faces along at least part of the length of each of the side plates. This produces a lightweight yet rigid seat base which enables a low block height. |
| US10988064B2 |
Epidermis material for vehicle seat
A cover material for a vehicle seat provides favorable touch while utilizing the texture of a leather material. A cover material for a vehicle seat includes: a leather portion made of natural leather or artificial leather; and a mesh fabric portion bonded to the back side of the leather portion. |
| US10988056B2 |
Child restraint headrest with side-wing mover
A juvenile vehicle seat includes a seat bottom and a backrest coupled to the seat bottom. The seat also includes a headrest coupled to the backrest. |
| US10988054B1 |
Vehicle swivel seat
A vehicle seat apparatus that includes a bottom assembly that is attached to a floor of the vehicle; a top assembly that is for the support of a seat structure; a turntable that is mounted between the bottom assembly and the top assembly and rotatable to allow rotational motion of the top assembly relative to the bottom assembly; and a lever mechanism secured to the top assembly and pivotal relative to the bottom assembly in order to pivot the top assembly and seat structure from a more forward position to a more sideways position so as to provide enhanced access to the seat structure. The vehicle seat apparatus is comprised of a base cushion and an upright member with only the base cushion being swivelled. |
| US10988052B2 |
Seat for vehicle
When an occupant stretches his/her lower extremity in a state where putting his/her foot on a foot resting portion during autonomous driving of a vehicle, a seat is controlled so as to move rearward and obliquely upward along a control portion. Concurrently, a seat cushion is controlled so that its front portion moves downward while being supported by a link member and then its inclination angle is made gentle. When at least one of a position and an angle of at least one of the seat cushion and the seatback is controlled, an upper end of the seat is located on an inclined straight line extending downward on a forward side of the upper end. |
| US10988051B2 |
Seat support mechanism
A seat support mechanism including a leg pedestal (11), which is fixedly provided on a floor in the vicinity of a side wall (A), a moving pedestal (20), which is disposed under a top face part (12) of the leg pedestal (11) and is capable of being advanced/retracted in a direction orthogonal to the side wall A; an underframe (30) of the seat, which is disposed above the top face part (12) of the leg pedestal (11), and is turnably supported by a turning shaft (41) in the moving pedestal (20), the turning shaft (41) avoiding an interference with the top face part (12), and an interlocking mechanism (50), which interlocks turning and advancing/retracting of the underframe (30), in which, when the seat is turned together with the underframe (30), the interlocking mechanism (50) converts the turning motion of the underframe (30) into a linear motion and, through the turning shaft (41), transmits it to the moving pedestal (20), thereby causing the moving pedestal (20) and the underframe (30) to be advanced/retracted in a direction orthogonal to the side wall (A). |
| US10988050B2 |
Section insulating device and use of same
A section disconnect device for a contact line assigned in particular to railborne vehicles as overhead line and carrying high voltage, having a single section arrangement (10) with multiple line sections extending, such that it is tensioned or can be tensioned, between two contact-wire connecting heads (12, 14) and provided with insulator means (36, 38), which line section arrangement is constructed such that it can be mounted by means of respective accommodating sections (66) of the contact-wire connecting heads in an electrically and mechanically contacting manner between exposed ends (16, 18) of the contact line, as a result of which at least one of the contact-wire connecting heads (12, 14) has adjustable level equalization means (66, 68, 70) for interacting with a head-side end (20, 24) of the line section arrangement (10), which are constructed in such a manner that, with respect to a current collector contact, in particular a current-collector-contact side of the contact line and/or a current-collector-contact plane, the free end of the contact line can be brought into a common plane with the end of the line section arrangement and/or seamlessly aligned with the same. |
| US10988044B2 |
Automatic plug-and-pay with multi-factor authentication for fueling vehicles
A charging station comprises a processor programmed to receive a vehicle identifier identifying a vehicle from a first digital entity; receive a payment authentication from a second digital entity; electronically identify an account associated with the vehicle identifier and the payment authentication; verify payment rights confirming a right to use the account to pay; and responsive to successful verification, activate the charging station to charge and process payment from the account. |
| US10988040B2 |
Charging gun with good heat conduction and heat dissipation performance
A charging gun having excellent heat conduction and dissipation performance, comprising a gun body, terminals, insulated sleeves, and a metal heat dissipation member; rear end portions of the terminals pass through the sleeves, the metal heat dissipation member is opened with mounting holes for inserting and fixing the sleeves, and the metal heat dissipation member is fixed to the gun body. The present solution prevents short circuiting by using metal heat dissipation member as a body for fixing the terminals and by using insulated sleeves to separate metal heat dissipation member from the terminals. Large ceramic members that conventionally fix terminals are removed, thus preventing the difficulty wherein a ceramic member having a large volume tends to break when a hole is opened thereon. Processes for processing the sleeves and opening the mounting holes on the metal heat dissipation member are all convenient, having a low level of machining difficulty. |
| US10988039B2 |
Power transfer device, control method and recording medium
A power transfer device comprises a power transfer coil; a case that has a surface extending along a direction perpendicular to an axial direction of the power transfer coil and stores the power transfer coil; a rotating shaft rotatable about the shaft that extends in the axial direction of the power transfer coil at a central portion in a radial direction of the power transfer coil and has an end penetrating the surface and protruding outward through the surface; a foreign object remover that projects outwardly from the end of the rotating shaft in a radial direction of the rotating shaft and moves on the surface; a driving source that provides the rotating shaft with power; and a processor that determines whether or not a vehicle is present. The driving source is driven if the processor determines that the vehicle is present. |
| US10988034B2 |
Antenna for an implantable device
An implantable device for deployment inside a human or animal body, the device comprising at least one sensing component arranged to respond to an electrical signal having a known frequency band and at least one antenna comprising at least one antenna pole connected to the at least one sensing component, the antenna pole comprising at least one helical coil and a connecting stem. |
| US10988033B2 |
Control system for a vehicle
A control system for a vehicle having a first wheel (101) arranged to be driven by a first drive source and a second wheel (101) arranged to be driven by a second drive source, wherein the first wheel and the second wheel are transversely located on the vehicle, the control system comprising a controller (102) and a monitoring device, wherein the monitoring device is arranged to monitor the power differential between the power being applied to the first wheel by the first drive source and the power being applied to the second wheel by the second drive source, wherein upon a determination that the power differential between the power being applied to the first wheel and the second wheel is greater than a predetermined value, the controller is arranged to reduce the power differential. |
| US10988032B2 |
Self-propelled personal transportation device
The present disclosure includes a transportation apparatus. The apparatus comprises: a surface to receive a plurality of forces at a plurality of locations thereon; a plurality of force sensors, attached to the surface, to provide information related to the plurality of forces; a plurality of wheels beneath the surface, each of the plurality of wheels being coupled with a motor; and a controller to: determine, based on the provided information, a first plurality of forces at the plurality of locations; determine, based on the first plurality of forces, a reference distribution associated with the plurality of locations; determine, based on the provided information, a second plurality of forces; determine a target speed and a target direction of the apparatus based on the reference distribution and the second plurality of forces; and provide one or more signals to the motors based on the target speed and the target direction. |
| US10988031B2 |
Method and device for adjusting a torque of a driven wheel of a motor vehicle
The invention relates to a method for operating a motor vehicle (1) which has at least one electric machine (7) which can be/is operatively connected to at least one driven wheel (6) of the motor vehicle (1), and a safety device (13) which is assigned to a driven wheel (6), is independent of the electric machine (7) and when necessary applies a positive or negative torque to the driven wheel (6), wherein the electric machine (7) is operated by an inverter (8). There is provision that the inverter (8) is monitored for incorrectly set torques, and that the safety device (13) is actuated as a function of a detected incorrect torque. |
| US10988027B2 |
Wheel well heating method
An exemplary wheel well heating method includes, among other things, in response to an environmental condition, generating thermal energy to heat a wheel well area of a vehicle. The method further includes powering the generating with power from a power source that is external to the vehicle. Another exemplary wheel well heating method includes generating thermal energy to heat a wheel well area of a vehicle, and adjusting the generating in response to a state of charge of a power supply of the vehicle. |
| US10988025B2 |
Energy storage robot
An energy storage robot configured to be used to power electric underground equipment, the energy storage robot including a propulsion system being arranged to move the energy storage robot, an energy storage unit, a control unit being connected to the propulsion system and the energy storage unit. The energy storage unit is connectable to the electric underground equipment for powering the electric underground equipment and the control unit is arranged to communicate a level of energy of the energy storage unit to a coordinating module or another energy storage robot. |
| US10988024B2 |
Display device
A display device is configured to, when displaying an indicator needle as rotating with a relatively small rotation amount per unit time, display an indicator needle image while rotating the indicator needle image, and, when displaying the indicator needle as rotating with a relatively large rotation amount per unit time, display an indicator-needle motion-blurred image that corresponds to a rotation range per unit time of the indicator needle. An indicator-needle inner end angle formed by two sides of the indicator needle image that form an end thereof that faces a center of the rotation is equal to a minimum motion-blurred inner end angle formed by two sides of the indicator-needle motion-blurred image that has the smallest rotation amount per unit time while the indicator needle is displayed as rotating, the two sides forming an end of the indicator-needle motion-blurred image that faces the center of the rotation. |
| US10988023B2 |
Autonomous driving assistance system, autonomous driving monitoring device, road management device, and autonomous driving information gathering device
An autonomous driving display system includes: an autonomous driving control device to carry out autonomous driving; an autonomous driving display device display state of which is recognizable from outside a vehicle; and an in-vehicle device to make the autonomous driving control device carry out autonomous driving of the vehicle upon receiving an autonomous driving instruction signal instructing autonomous driving, monitor start of the autonomous driving of the vehicle by the autonomous driving control device, and control a display state of the autonomous driving display device to be in a display state different from a display state before the autonomous driving is started when the autonomous driving of the vehicle is started by the autonomous driving control device. |
| US10988016B2 |
Hydraulic bearing
A hydraulic mount, in particular for mounting a motor vehicle engine, includes a mount core, a supporting spring comprising an elastomer material, a working chamber delimited by the supporting spring, and a compensation chamber separated from the working chamber by an intermediate plate. The working chamber and the compensation chamber may be filled with hydraulic fluid and connected to each other by a flow transfer duct. The mount core may have a first mount core part and a second mount core part operationally connected to each other by an elastomer body for high-frequency vibration decoupling. The elastomer body has a first elastomer body portion configured to absorb at least a static mount load acting on the mount core, and a second elastomer body portion configured to absorb at least a transverse force acting on the mount core. |
| US10988009B1 |
Limiting structure and rear compartment cover system for pickup truck
A limiting structure and a rear compartment cover system for a pickup truck are described. The limiting structure includes a mounting base, two limiting blocks separately arranged on two sides of the mounting base, a pulling member driving the two limiting blocks to retract toward the mounting base, and a springback member driving the limiting blocks to extend in a direction away from the mounting base always, the two limiting blocks being both movably connected to the mounting base. This application has effects of convenient and fast operations and being convenient to take out goods from or place goods in the compartment. |
| US10988006B2 |
Door for vehicle
A door of a vehicle may include a door internal panel; a door external panel mounted outside a passenger compartment with respect to the door internal panel, detachably coupled to the door internal panel, and made of a lightweight material than the door internal panel; and a reinforcement member mounted between the door external panel and the door internal panel and fastened to the door external panel and the door internal panel to increase rigidity, reducing weight and cost of the door of the vehicle and easily replacing the door external panel. |
| US10988005B2 |
Vehicle door structure and method for manufacturing the same
A vehicle door structure includes a mirror retainer having a main body, which is joined to the front end of an outer reinforcement with a part of the main body overlapping with the outer reinforcement. The mirror retainer includes an upper leg, which has a first facing surface facing a lower leg and is joined to the inner panel. The lower leg has a second facing surface facing the upper leg and is joined to the inner panel. A reinforcing member is connected to the first facing surface and at least one of a main body inner surface and the second facing surface so as to reinforce the mirror retainer. |
| US10988001B2 |
Air conditioning device for vehicle
An air conditioning device for a vehicle includes a first flow path through which air subject to dehumidification flows, a second flow path through which air for recovery flows, a desiccant part and a controller. The desiccant part is fluidly communicated with the first and second flow paths, and configured to adsorb moisture contained in the air subject to dehumidification, and to discharge the moisture to the air for recovery. The controller is configured to control an air volume of the air subject to dehumidification and an air volume of the air for recovery so that the air volume of the air for recovery is less than the air volume of the air subject to dehumidification, after the air volume of the air for recovery reaches a prescribed air volume for achieving a target dehumidification amount of the air subject to dehumidification. |
| US10987996B2 |
Baby comfort monitoring system and method
A system and method are disclosed for a vehicle that comprises one or more sensors configured to obtain information indicating a physical state of a baby. A wireless transceiver may be included and in communication with a mobile device. The transceiver may be configured to connect mobile device with a camera configured to monitor the baby. A controller may also be in communication with the one or more sensors and the wireless transceiver. The controller may be configured to determine the physical state of the baby utilizing the information obtained from the one or more sensors. The controller may also be configured activate one or more vehicle systems in response to the physical state of the baby and to output on a vehicle display or the mobile device a notification to a user indicating the physical state of the baby. |
| US10987994B2 |
Air-conditioning system and climate control method for a fuel cell vehicle
An air-conditioning system and method of climate control for a fuel cell vehicle are provided herein. The system and method include a vacuum enclosure having an adsorber and an evaporator/condenser assembly. A conduit and valve system operates the air-conditioning system in two modes of operation to provide uninterrupted cooling to a passenger cabin, among other things. In one mode of operation, the adsorber is regenerated using waste heat from a fuel cell stack. |
| US10987993B2 |
Thermal management system for electrified vehicle
A vehicle thermal management system including an engine, a vehicle cabin, a transmission thermal loop, and a controller is provided. The transmission thermal loop may include a transmission assembly in operational communication with the engine and a cabin thermal loop. The controller may be programmed to, responsive to detection of an engine off condition, output to a shut-off valve an open command such that heat from the transmission thermal loop transfers to the cabin thermal loop to warm the vehicle cabin. The controller may be further programmed to, responsive to detection of a cabin heater core having a temperature above a predetermined threshold, output a command to a coolant heater of an engine thermal loop to direct warm or cold fluid to the transmission assembly based on a detected transmission thermal loop temperature. |
| US10987991B2 |
Air conditioning unit for vehicle
An air conditioning unit for a vehicle includes: an air conditioning case, a blower that draws air from an opening and blows the air radially outward from its rotation axis, a cooler disposed upstream of the blower, and a heater is disposed downstream of the blower. The air conditioning case includes an upper bypass passage through which the air bypasses the heater on an upper side of the heater, a lower bypass passage through which the air bypasses the heater on a lower side of the heater, a first opening provided downstream of the upper bypass passage, and a second opening provided downstream of the lower bypass passage. The opening of the blower faces an air outflow face of the cooler. A passage area of the upper bypass passage is larger than a passage area of the lower bypass passage. |
| US10987989B2 |
Adjustable vehicle suspension system
A damping control system for a vehicle having a suspension located between a plurality of ground engaging members and a vehicle frame includes at least one adjustable shock absorber having an adjustable damping profile and a driver actuatable input. The driver actuatable input may be positioned to be actuatable by the driver in the absence of requiring a removal of either of the hands of the driver from a steering device of the vehicle. |
| US10987986B2 |
Suspension device
A suspension device includes knuckles that rotatably retain rear wheels, an electric actuator that steers the rear wheels, paired tie rods that are connected to the electric actuator via a link mechanism and driven back and forth by the electric actuator, brackets that are rotated by the tie rods, and a lower arm attached to the brackets. Each bracket is rotatable between the knuckle and the lower arm. |
| US10987977B2 |
Systems and methods for measuring tire wear using embedded image sensors
A tire wear tracking system including network interface hardware configured to communicatively couple a vehicle with a remote server, a processor, and a memory module that stores one or more processor-readable instructions. When executed by the processor, the one or more processor-readable instructions cause the tire wear tracking system to receive image data of one or more tires of a vehicle from one or more image sensors, determine tire information associated with the one or more tires, retrieve reference image data based on the determined tire information, compare the received image data with the retrieved reference image data; and generate an alert based on the comparison between the received image data and the retrieved reference image data. |
| US10987972B2 |
Wheel apparatus for self-propelled irrigation system
A wheel apparatus for a self-propelled irrigation system has a center portion, a rim assembly, and a support structure disposed between the center portion and the rim assembly. The rim assembly has a plurality of rigid members spaced apart from each other with longitudinal axes that are parallel with each other and equidistant from the axis of rotation. The rigid members are cylindrical with unsupported ends, and a mounting portion between the ends is connected to an outer periphery of the support structure. The rigid members are held in a fixed position relative to the center portion by the support structure. The rigid members are arranged to contact the ground surface to support the irrigation system with spaces between the rigid members allowing mud and debris to pass freely between the rigid members during operation to enhance traction while minimizing mud from being forced out of a wheel track. |
| US10987968B2 |
Non-pneumatic support structure
A wheel and tire assembly for a mobile vehicle in accordance with the present invention includes an inner central rim, a flexible ring mounted on the inner central rim, and a spoke structure extending between the inner central rim and the flexible ring. The spoke structure defines a plurality of cavities and alternating radially extending openings disposed concentrically about the inner central rim and allowing the flexible ring to deflect under load. The spoke structure further defines a plurality of triangular openings disposed at the flexible ring and between the cavities and the inlet openings. |
| US10987966B2 |
Appreciation card with hidden gift card slot
An appreciation card including a front panel having a window formed therein that is located between the left side and the right side of the front panel and being defined by a window border. A gift card panel is disposed on the back face of the front panel below the window border. The gift card panel includes a pocket section and an attachment tab, the pocket section being connected to the window border on a first end and to the attachment tab at an opposing second end, the attachment tab being adhered to the back face of the front panel, and the pocket section being free from the back face of the front panel. The front panel and the gift card panel define a gift card slot into which a gift card may be inserted. |
| US10987964B2 |
Post-processing apparatus
A post-processing apparatus includes: a first binding unit that binds sheets and moves while rotating a first gear; a second binding unit that binds sheets and moves while rotating a second gear; a common path that is a path along which the first binding unit and the second binding unit move; a first rack gear that is provided along the common path and meshes with the first gear; and a second rack gear that is provided along the common path at a side opposite to the first rack gear with the common path interposed between the second rack gear and the first rack gear, and meshes with the second gear. |
| US10987958B2 |
Printer cover
A printer cover is mounted on a tape printer that includes a plurality of housing faces that include a first housing face in which a first cavity opening portion of a cartridge mounting section into which a tape cartridge is mounted is formed and a lid member that openably closes the first cavity opening portion. The printer cover is an integrally formed body having elasticity. The printer cover has cover faces that include the first cover face that covers the first mounting-side housing face, and a first lid-exposure opening that is provided in the first mounting-side cover face and through which lid member is exposed. |
| US10987955B2 |
Printer
A printer includes a first roller, a second roller, a motor and a head. The printer includes a controller configured to control the head and the motor to print a first pattern comprising a plurality of first pattern elements on the sheet by alternately repeating, ejecting a liquid droplet to print one of the first pattern elements on the sheet and conveying a sheet in a conveyance direction by a first distance. The controller is configured to, after printing the first pattern on the sheet, control the motor to convey the sheet in the conveyance direction by a second distance and control the head to eject the liquid droplet to print a second pattern on the sheet without conveying the sheet, a respective first pattern element and a corresponding second pattern element being disposed at a same location in a direction orthogonal to the conveyance direction. |
| US10987954B2 |
Load stops
In an example, a load stop may comprise a stop paddle, a paddle link, a swingarm engaged with a motive element, and a cam gear to engage the swingarm with the paddle link. The paddle link may move the stop paddle from a locked position, to a gathering position, and to a stowed position. The swingarm may transfer the motion of the motive element to the cam gear such that the cam gear is to move in a first direction, the cam gear to drive the paddle link to move the stop paddle from the locked position, to the gathering position, and to the stowed position when the motive element moves in a first drive direction, and the swingarm moves the cam gear in the first direction. |
| US10987943B2 |
Expansion device, three-dimensional image forming system, thermally-expandable sheet, three-dimensional object shaping method, and computer-readable storage medium
An expansion device includes: a thermal distension unit configured to thermally distend a thermally-expandable sheet by irradiating the thermally-expandable sheet with predetermined energy; a reading unit configured to read identifiers provided at predetermined positions of the thermally-expandable sheet; and a setting unit configured to set an amount of energy per unit area to be emitted on the thermally-expandable sheet by the thermal distension unit depending on whether (i) a second identifier as well as a first identifier has been read, or (ii) whether a predetermined part of the first identifier has been read but another part has not been read, as a result of reading the identifiers by the reading unit. |
| US10987938B2 |
Image processing device generating print data for printer provided with print head having a plurality of nozzles
An image processing device is communicable with a printer and includes a controller. The printer is configured to repeatedly and alternately execute a partial print and a sub scan to form an image. The image is made up of a plurality of partial images arranged in a sub scanning direction. The partial print forms a target partial image while performing a main scan. The controller is configured to perform: setting; generating; and outputting. The setting sets a printing direction for the partial print to one of first and second directions. The generating generates partial print data for the partial print by executing a color conversion process on target partial image data using a color conversion profile. The color conversion profile is selected from first and second profiles respectively corresponding to the first and second directions. The outputting outputs the partial print data and direction information specifying the printing direction. |
| US10987935B1 |
Organic solvent sealing tape
A fluidic ejection cartridge and protective tape therefor. The fluidic ejection cartridge has a cartridge body for an organic solvent-based fluid having a cover closing a first end thereof, an ejection head on a second end thereof opposite the first end, and side walls attached to the first and second ends between the first and second ends, wherein the side walls comprise a first side wall, a second side wall opposite the first side wall, a first end wall attached to the first and second side walls, and a second end wall opposite the first end wall attached to the first and second side walls. A removable tape is attached to a nozzle plate of the ejection head and to a portion of the first side wall, wherein the removable tape comprises a polymeric backing film and a platinum-cured silicone adhesive. |
| US10987933B2 |
Platen assembly for sheet fed printer
A printer includes: a platen having an ink-collection slot extending across its width; a wick bar received in the ink-collection slot, wherein an upstream gap and a downstream gap are defined at either side of the wick bar relative to a media feed direction; a printhead positioned over the wick bar; and a vacuum chamber in fluid communication with the ink-collection slot. The wick bar is absent from a mid-portion of the platen and the mid-portion of the platen is aligned, in the media feed direction, with an upstream media picker. |
| US10987924B2 |
Method for printing an image using liquid ink
A method for printing an image with improved printing quality using liquid ink includes using a pump to pump ink to a print head for printing rows of the image onto a moving printing substrate. A respective value correlated with the amount of ink required to print the rows is calculated for a plurality of individual rows or a plurality of grouped rows of the image. The pump receives a preemptive control signal based on the calculated values. |
| US10987923B2 |
Liquid circulation device and liquid discharge device
A liquid circulation device includes a first pipe, a first pump, a first portion, a second pipe, a second pump, a second portion, and a heater. A secondary side of the first pipe is connected to a liquid discharge head. The first pump is provided midway through the first l pipe. The first portion is provided midway through the first pipe on a secondary side of the first pump, and includes a flow channel cross-sectional area larger than the area of the first pipe. A primary side of the second pipe is connected to the head. The second pump is provided midway through the second pipe. The second portion is provided midway through the second pipe on a primary side of the second pump, and includes a flow channel cross-sectional area larger than the area of the second pipe. The heater is provided on a primary side of the head. |
| US10987919B2 |
Recording apparatus and recording method
A recording apparatus is provided for determining a relative moving speed between a recording head and a recording medium based on application amount information and power information corresponding to power for driving a heating element. In a case of the power amount in a first amount, the moving speed is determined as a first speed in a case where an application amount is equal to a predetermined amount, and the moving speed is determined as a speed higher than the first speed in a case where the application amount is smaller than the predetermined amount. In a case of the power amount in a second amount smaller than the first amount, the moving speed is determined as a speed higher than the first speed in a case where the application amount is equal to the predetermined amount. |
| US10987913B2 |
Pad removal device and method
A pad removal device includes a pad guide extending along a first direction. The pad guide includes a first affixing component configured to affix a first end of the pad guide to a pad at a first pad edge location, and a second affixing component configured to affix a second end of the pad guide to the pad at a second pad edge location opposite the first pad edge location. The pad removal device further includes an actuator attached to the pad guide, and a control assembly coupled to the actuator and configured to cause the actuator to move the first end toward the second end along the first direction. The pad guide is configured to extend in a second direction different from the first direction by an amount dependent on a distance between the first end and the second end. |
| US10987903B2 |
Laminated glass
There is provided a laminated glass excellent in sound insulating property. A laminated glass includes: a pair of glass plates facing each other; and an intermediate film sandwiched between the pair of glass plates, including alternately laminated at least one skin layer and two or more core layers, wherein the skin layer has a glass transition point of 15° C. or higher, and each of the core layers has a glass transition point of less than 15° C., and a ratio of a mass of the intermediate film with respect to a total mass of the intermediate film and the pair of glass plates is 14 mass % or more. |
| US10987900B2 |
Article
An article includes a substrate and a structure of additive manufacturing material of predetermined thickness attached to the substrate, the structure of additive manufacturing material formed by providing a metal alloy powder, forming an initial layer having a preselected thickness and a preselected shape including at least one aperture, with the metal alloy powder, sequentially forming an additional layer with the metal alloy powder over the initial layer, each of additional layers having an additional preselected thickness and an additional preselected shape including an aperture corresponding to the aperture in the initial layer, and joining each of the additional layers to the initial layer or any previously joined additional layers, forming a structure having a predetermined thickness and shape, and an aperture having a predetermined profile. The article includes a passageway through the structure including the aperture and a corresponding metering hole. |
| US10987895B2 |
Roof member or ceiling member, and construction
Described herein is a roof member or a ceiling member, which is capable of reducing cooling and heating energy consumption by reducing influent and effluent heat amounts between indoor and outdoor environments in such a situation that the indoor temperature is kept constant by use of cooling and heating equipment independently of the outdoor air temperature changes. The disclosed member for roofing or ceiling includes an outdoor-side heat insulating layer (A); an indoor-side heat insulating layer (B); and a heat storage layer between the outdoor-side heat insulating layer (A) and the indoor-side heat insulating layer (B). |
| US10987890B2 |
Binding apparatus
A binding apparatus includes: a first toothed part including teeth arranged in one direction; and a second toothed part that includes teeth arranged in the one direction and is configured to mesh with the first toothed part and to press a bundle of sheets, wherein at least one first groove is formed between adjacent teeth of the first toothed part, the first groove has cross-sectional areas at central and end portions in a direction orthogonal to the one direction and a direction in which the first and second toothed parts mesh with each other, the one direction and the orthogonal direction are normal to the cross-sectional areas, and the cross-sectional area at the end portion is larger than the cross-sectional area at the central portion. |
| US10987887B2 |
Method for loading a green tyre for bicycle in a vulcanisation mould and apparatus for moulding and vulcanising
A green tyre (2) for bicycles is built, comprising at least one carcass ply (4) having axially opposite end flaps (4a) engaged with respective bead cores (5) and a tread band (6) applied in a radially outer position around said at least one carcass ply (4). The built tyre (2) removed from the building drum, is profiled so as to translate the tread band (6) in a radially outer direction with respect to the bead cores (5), so as to impart a cross-sectional convex profile to the tyre (2) in a radially outer direction. The profiled tire is engaged by means of a transfer member (31) comprising a gripping device (30) which holds it hanging and loads it into a vulcanisation mould (101) by axially positioning an axial centreline plane (M) of the green tyre at an axial reference (51) arranged at a predetermined height along a reference axis (K) of a central body (103) of the vulcanisation mould (101). |
| US10987884B2 |
Method of forming antireflection optical body, display panel, and optical film
A method of forming an antireflection optical body includes: an application step of applying a photocurable resin onto one surface side of an adherend; a pressing step of pressing a substrate film having a fine structure body at one surface side against the photocurable resin from an opposite surface side by a light guide; a curing step of curing the photocurable resin by transmitting light through the light guide; and a peeling separation step of releasing the pressing of the substrate film and peeling fixed fine structure body that is fixed to the adherend through the cured photocurable resin substrate film while separating the fixed fine structure body from fine structure body on the substrate film other than at a location fixed through the photocurable resin such that the fixed fine structure body is formed on the adherend as an antireflection optical body. |
| US10987883B2 |
Glass repair kit and method
A portable glass repair kit system and method, more particularly, for windshield repair for laminated glass and the like to provide an easy to use, highly portable, and economical glass repair kit. The glass repair kit does not require specialized equipment such as an injector, plugger device, suction cups, or require any additional tools or specialized knowledge of how to use the repair kit. The glass repair kit contains a resin which may be urged by a user through slight pressure after the glass repair kit is adhered over an impact point and any cracks thereby repairing a windshield in a more cost effective, time efficient, and user friendly way. |
| US10987877B2 |
Method for producing a vehicle component from a fiber-reinforced plastic
A method for producing a vehicle component from a fiber-reinforced plastic including providing a skin panel having an inner side, outer side and mounting portion. The skin panel is a fiber-reinforced thermoplastic material. At least one stiffening component has a connection surface. The stiffening component is a fiber-reinforced thermoplastic material. The stiffening component and skin panel are contacted wherein the connection surface lies on the mounting portion. The method includes areally warming a joining zone so the stiffening component and skin panel are welded together. The joining zone is cooled. A determined geometry of the combination of stiffening component and skin panel is compared with a predefinable geometry. The joining zone is re-warmed, deforming the stiffening component and the skin panel, and the method includes cooling in order to attain the predefinable geometry if the determined geometry deviates from the predefinable geometry. |
| US10987876B2 |
Joining components
A method for joining a first component and a second component. The method includes forming a first bond between the first component and the second component by providing a plurality of projections on the first component and embedding the plurality of projections in the second component; creating a fastener hole which passes through the first component and the second component and which encompasses at least one of the projections; and forming a second bond between the first component and the second component by installing a fastener in the fastener hole. |
| US10987872B2 |
System and method for producing dental solutions incorporating a guidance package
A method of producing a retention piece having a guidance package configured to provide a desired movement profile including: obtaining data descriptive of mandibular and maxillary arches, an index position of the mandibular arch at a maximum closure position, and a temporomandibular joint of a recipient; specifying an appropriate guidance package based on the desired movement profile; positioning a retention piece comprising at least a portion of the specified guidance package about virtual representations of at least one of the mandibular and maxillary arches within a virtual articulator; modeling relative movement of the virtual representations of the mandibular and maxillary arches within the virtual articulator; and generating data that can be used by a computer aided machining (CAM) process to create at least one physical retention piece comprising the specified guidance package configured to provide the desired movement profile. |
| US10987869B2 |
Continuous pull three-dimensional printing
Described herein are three-dimensional (3D) printer systems and methods, which may provide for “continuous pull” 3D printing. An illustrative 3D printer includes: a resin container, a base plate, a light source arranged below the resin container and operable to cure resin in the resin container; and a control system operable to: (a) receive model data specifying a 3D structure; (b) determine 2D images corresponding to layers of the 3D object; and (c) generate control signals to operate the light source and the base plate to sequentially form the layers of the 3D object onto the base plate, wherein the base plate moves a formed portion of the 3D object upward after formation of each layer, and wherein at least a surface of a formed portion of the 3D object remains in contact with the resin in the resin container throughout the formation of the layers of the 3D object. |
| US10987862B2 |
Three-dimensional shaping device
A three-dimensional shaping device includes a melting section configured to melt a material to generate a shaping material, a supply flow channel which is communicated with the melting section, and through which the shaping material flows, a nozzle communicated with the supply flow channel and configured to eject the shaping material, an ejection amount control mechanism provided to the supply flow channel, and configured to control a flow amount of the shaping material to be ejected from the nozzle, a branch flow channel branched from a first partial flow channel as a flow channel between the melting section and the ejection amount control mechanism out of the supply flow channel, and communicated with a second partial flow channel as a flow channel between the ejection amount control mechanism and the nozzle out of the supply flow channel, and a transfer mechanism configured to transfer the shaping material in the second partial flow channel to the first partial flow channel via the branch flow channel. |
| US10987853B2 |
Method and systems for applying stretch films/plastic films at a controlled temperature and/or transfer of electrostatic charge
A system for controlling the temperature of a film before and/or during application, the system including: a heat source for heating a film; and stretch rollers; wherein the heat source heats the film from an ambient temperature to a temperature from about 2° C. to about 40° C. above the ambient temperature, wherein the film is heated prior to or simultaneous to being stretched by the stretch rollers, and wherein the ambient temperature is below 15° C. A system for improving the application of film by transfer of electrostatic charge is also described. The preheating system and/or electrostatic charge system may be used to enhance binding and sealing properties of stretch films used for wrapping palletized products in a reduced temperature environment. Other embodiments of the preheating film system and electrostatic charge system, and methods for their use, are described herein. |
| US10987851B2 |
Nozzle for blow-molding stepped finish preform
An apparatus for a nozzle is provided for engaging with lightweight preforms for blow-molding the preforms into plastic containers without damaging the finish portion of the preforms. The nozzle comprises a first cylindrical portion including a first seal, a second cylindrical portion including a second seal, and a tapered portion between the first and second cylindrical portions. The first and second cylindrical portions include diameters that are less than respective diameters of interior surfaces within the finish portion. The first and second seals are disposed around respective circumferences of the first and second cylindrical portions and configured to tightly engage with the interior surfaces of the preform while maintaining clearance between the nozzle and the interior of the finish portion. In some embodiments, the seals are configured to stabilize an orientation of the preform after being pressed onto the nozzle and facilitate conveying the preform along a manufacturing line. |
| US10987847B1 |
Die structure
A die structure is provided. The die structure may have a die body, a mandrel having a magnet and/or one or more magnet assemblies, a first magnetic structure, a second magnetic structure and/or one or more magnetic structures. The first magnetic structure may be configured to apply a first magnetic force to the mandrel, in a first direction. The second magnetic structure may be configured to apply a second magnetic force to the mandrel, in a second direction opposite the first direction. The one or more magnetic structures may be configured to apply one or more magnetic forces to the mandrel. Application of the first magnetic force, the second magnetic force and/or the one or more magnetic forces to the mandrel supports the mandrel to be levitated within the die body and/or causes the mandrel to rotate and/or to maintain a position within the die body. |
| US10987845B2 |
Multi-material extruder and extrusion method for three-dimensional (3D) printing
There is disclosed a multi-material extruder and extrusion method for 3D printing, and more particularly to an apparatus and method that is adapted to extrude a wide range of materials for printing 3D structures. In an aspect, the apparatus comprises a frame adapted to receive a removable syringe or cartridge with a depressible piston in an extended position, the syringe or cartridge containing material to be extruded. An extrusion motor is under the control of an extruder logic module to determine how quickly the piston of the syringe or cartridge is to be depressed to achieve a desired rate of extrusion of the material. A flexible length of tubing connects the tip of the syringe or cartridge to an extruder nozzle, which nozzle is mounted to a stylus which may be hand-held or mounted to a chassis of a 3D printing device. A feedback signal is used to provide a feedback signal to the extruder logic module to determine the rate of extrusion of material. The syringe or cartridge may include a label containing information on the type of material in the syringe or cartridge, and one or more extrusion parameters to be used with the material in the syringe or cartridge. |
| US10987844B1 |
Clamping mechanism assembly
The present disclosure provides a clamping assembly in operative connection with a mold of an injection-molding apparatus. The clamping assembly includes a fixed plate, a rear plate, a plurality of tie bars, a movable plate, a driving module, and a temperature adjuster. The rear plate is spaced apart from the fixed plate. The tie bars are interlinked with the fixed plate and the rear plate and provided with a plurality of channels. The movable plate, between the fixed plate and the rear plate, is capable of moving with respect to the fixed plate along the tie bars. The driving module interlinks the rear plate and the movable plate. The temperature adjuster is employed to supply a fluid into the channels to remove heat from the tie bars, thereby preventing non-uniform thermal expansion of the tie bars, and hence preventing the structural wear and flash issues. |
| US10987841B2 |
Determining process parameter values in an injection moulding process
The invention describes a method of determining a number of process parameter values within an injection mould (1F) during an injection moulding process, which method comprises the steps of determining geometric data of the injection mould (1F) and/or of a form part (1, 1′, 1″) to be manufactured, determining a virtual part-specific pressure curve (pS) of an injection moulding process, determining a part-specific event pattern (MS) on the basis of the virtual part-specific pressure curve (pS), carrying out an injection moulding process using the injection mould (1F) and determining a measured pressure curve (pm) during the injection moulding process and determining a measurement event pattern (Mm) on the basis of the measured pressure curve (pm). Process parameter values are derived on the basis of the virtual event pattern and the measurement event pattern. The invention further describes a corresponding process parameter value determining apparatus and an injection mould arrangement. |
| US10987835B2 |
Method and device for casting a ring-shaped plastic frame in a recess of a rotor disk of a double-sided machining machine
A method for casting a ring-shaped plastic frame comprises providing two mold parts, wherein at least one of the two molds parts includes at least one ring-shaped seat. Positioning a rotor disk between the two mold parts where the rotor disk comprises at least one annular recess. Engaging a mold core with at least a portion of each of the two mold parts. The mold core comprises at least one casting channel configured to attach at one end to a supply of plastified plastic. Inserting at least one mold insert into the at least one ring-shaped seat. A mold volume is defined by the at least one mold insert, the mold core and an edge of the at least one annular recess, wherein the mold volume is configured to fluidly connect with the at least one casting channel to receive plastified plastic to form a plastic frame. |
| US10987831B2 |
Dies for forming a part and associated systems and methods
Disclosed herein is a die for forming a part. The die comprises a base, comprising a heat-platen interface surface and a part interface surface, and wherein the heat-platen interface surface and the part interface surface are separated by a thickness of the base. The die also comprises inserts, embedded within and circumferentially closed by the base, spaced apart from each other, and extending in a first direction from the heat-platen interface surface toward the part interface surface. The base is made of a first material having a first thermal conductivity. The inserts are made of a second material having a second thermal conductivity. The first thermal conductivity is different than the second thermal conductivity. |
| US10987829B2 |
Concrete drum control, property prediction, and monitoring systems and methods
A vehicle includes a chassis, an engine, a drum assembly, and a control system. The drum assembly includes a drum configured to receive drum contents and a drive system coupled to the drum. The drive system is configured to rotate the drum to agitate the drum contents. The control system is configured to operate the drive system at a drive speed; receive data comprising at least one of (i) a drum speed command from a remote monitoring system, (ii) a signal from a mixture sensor configured to acquire mixture data indicative of a current property of the drum contents, (iii) the current property of the drum contents from the remote monitoring system, and (iv) an initial property of the mixture from at least one of a batching system, the mixture sensor, and a user input device; and adjust the drive speed of the drum based on the data. |
| US10987828B2 |
Concrete product machine mold assembly stripper head support
A device for supporting stripper head on a mold box of a concrete product machine mold assembly. The device includes a set of attachment hardware that connects a stand-off leg to a stripper head plate to support the stripper head with the stripper head plungers disposed in respective protected positions within respective plunger receptacles of the mold box. The hardware set comprises a ferrous metal portion configured to be carried by the stripper head plate and a magnetic portion carried by the stand-off leg in a position to magnetically engage the ferrous metal portion and allow for removable attachment of the stand-off leg to the stripper head plate when the ferrous metal portion is carried by the stripper head plate. |
| US10987827B1 |
Methods and apparatuses for curing concrete
An apparatus for curing concrete includes a multiple layer polyolefin film and an absorbent layer. The polyolefin film layer can include pH modifying components and antiskid components. The absorbent layer can also include pH modifying components. The absorbent layer can include nonwoven fabric. The apparatus can be applied to curing concrete after hydration water is applied to the curing concrete. The apparatus can also be used to enclose poured concrete members during transport of the members so as to continue the curing process during transport. The film can also be used as a barrier layer between the ground and poured concrete. |
| US10987824B2 |
Method for coating uneven surfaces, apparatus as well as component
The present invention relates to a method and an apparatus (40, 50) for coating an uneven surface of a workpiece (W), wherein the apparatus (40, 50) comprising a first feeding device (41), through which a coating material (10) applicable to a workpiece (W) is fed, the coating material (10) comprising at least one weakened area (10a), a joining device for the application of the coating material to at least two workpiece sides (W1-W), wherein the at least one weakening area (10a) being positioned in the transition section of the at least two workpiece sides (W1-W2), and a second feeding device (70), through which the workpiece is fed and the transition section of the two workpiece sides (W1, W2) being formed to at least partially fill the weakened area of (10a) of the coating material (10) which is positioned in the transition section during the application of the coating material. |
| US10987821B2 |
Food processor
A food processor includes a base including a first end and a second end, a fixing member, a spindle assembly, a bearing assembly, a switching member mounted on the fixing member, and a cutter. The first end is provided with a tool rest for fixing the cutter to cut food. The fixing member is mounted on the first end. The spindle assembly includes a spindle rotatably mounted on the fixing member and a fluted disc fixed to the spindle for fixing the food. The bearing assembly includes a bearing block mounted on the fixing member and a bearing mounted on the bearing block. When the switching member is in an open position, friction is generated between the bearing and the spindle. When the switching member is in a closed position, the switching member can drive the bearing away from the spindle so that the spindle can freely move. |
| US10987820B2 |
Adjustable body shaver, system and method
The present application is directed to a hand held wet body shaver. The body shaver includes a razor assembly with one or more cutting edges. The razor assembly is adjustable amongst a plurality of fixed settings, each setting dictating the usable length of the one or more cutting edges. The razor assembly is operationally configured maintain a desired alignment amongst its component parts at each fixed setting. The razor assembly is effective for shaving and trimming hair to various desired lengths. |
| US10987817B2 |
Industrial robot with a weight counterbalance system
The invention relates to an industrial robot (1) having a robot arm (2) with a plurality of axes (9, 10) designed for a high payload and having a weight equalization system (12) based on gas for at least one of the axes (9), whose pressurized components (13-15) each have a volume of less than 1 liter and a maximum pressure of less than 1000 bar. |
| US10987804B2 |
Robot device and non-transitory computer readable medium
A robot device includes a detector and a controller. The detector detects a surrounding situation. If the robot device is unable to execute a solution for solving a problem in the surrounding situation by using a function of the robot device, the controller performs control so that the solution will be executed by using an element other than the robot device. |
| US10987801B2 |
Kinetic and dimensional optimization for a tendon-driven gripper
A tendon-driven robotic gripper is disclosed for performing fingertip and enveloping grasps. One embodiment comprises two fingers, each with two links, and is actuated using a single active tendon. During unobstructed closing, the distal links remain parallel, creating exact fingertip grasps. Conversely, if the proximal links are stopped by contact with an object, the distal links start flexing, creating a stable enveloping grasp. The route of the active tendon and the parameters of the springs providing passive extension forces are optimized in order to achieve this behavior. An additional passive tendon is disclosed that may be used as a constraint preventing the gripper from entering undesirable parts of the joint workspace. A method for optimizing the dimensions of the links in order to achieve enveloping grasps of a large range of objects is disclosed and applied to a set of common household objects. |
| US10987798B2 |
Wearable chair
A wearable chair may include a foot frame configured to support a foot of a user; a shank link configured to rotatably connect to the foot frame; a connecting link provided in front of the shank link and configured to rotatably connect to the foot frame; a knee link configured to rotatably connect to each of the shank link and the connecting link; and a thigh link configured to extend from the knee link. The foot frame, the shank link, the connecting link, and the knee link constitute a four-bar linkage. |
| US10987796B2 |
Engine stand
A wheeled engine stand and a process of using the engine stand is provided. The engine stand provides a wheeled base supporting a mounting head with retainers. The mounting head is reversibly attached to a drive shaft through, a retaining pin extending through a mounting head collar. A steering handle is detachably supported on an upper adaptor plate to allow for movement for the wheeled base. |
| US10987794B2 |
Accumulator-operated hand-held working apparatus as well as method for operating such an apparatus
An assembly including an accumulator-operated hand-held working apparatus and a functional module, and method of operating same is provided. The apparatus includes a drive, an accumulator, and a control device, which has a data storage element and a microprocessor. In response to a trigger impulse, the control device can automatically control a performance of a work process. A radio module of the functional module, which can optionally be connected to the apparatus. A connection can be established in the functional module in terms of conduction only for the power supply upon a connection to the apparatus, or can inductively be supplied with power. |
| US10987790B2 |
Cordless concrete nailer with improved power take-off mechanism
A power take-off (PTO) assembly of a cordless electric concrete driver includes a bracket supporting a solenoid and a compression spring and a linkage arm coupled between a plunger of the solenoid and the compression spring. The linkage arm is biased by the compression spring toward the nail driver. A carrier supports or carries a pinch roller and the carrier is pivotably mounted to the bracket via a pivot pin. An engaging surface is movable with the plunger between an engagement position in which the engaging surface engages a cooperating engaging surface of the carrier and orients the carrier into a corresponding engagement orientation, and a disengagement position in which the engaging surface is spaced away from the cooperating engaging surface of the carrier, allowing the carrier to pivot outside the corresponding engagement orientation. |
| US10987789B2 |
Production aid
A production aid for positioning at least one component relative to a further component includes a monolithic positioning main body configured such that, given its prescriptively correct arrangement on the further component, it predefines a prescriptively correct positioning of the component relative to the further component. The positioning main body includes at least one opening, into which a spacer bushing is positively fitted. The spacer bushing has a through hole through which a positioning pin is guided, or a positioning pivot, which is configured monolithically with the spacer bushing. The positioning main body, via the positioning pin or the positioning pivot, makes contact with the further component, and a longitudinal center axis of the through hole is arranged parallelly offset from a longitudinal center axis of the positioning pin or pivot. |
| US10987788B2 |
Systems and methods for removing bearing cups
A bearing cup removal tool for removing a bearing cup from a bearing casting comprises a collar assembly and a displacing assembly. The collar assembly comprises a clamp member and a clamp assembly, where the clamp member defines a clamp surface. The clamp assembly deforms the clamp member to alter a shape of the clamp surface such that the clamp member may be configured to surround at least a portion of the bearing cup and the clamp member may be configured to frictionally engage at least a portion of the bearing cup to secure the clamp member to the bearing cup. The displacing assembly engages the clamp member and is adapted to engage the bearing casting such that operation of the displacing assembly forces the clamp member away from the bearing casting. |
| US10987787B2 |
Adjustable light attachment for extension tool
A method of illuminating a target area and driving rotation a driven tool comprises coupling a light attachment assembly to an elongated extension member by placing a portion of the elongated extension member within a hollow portion of a sheath of the light attachment assembly. Activating a light source of the light attachment assembly. Positioning the driven tool within the target area while grasping the light attachment assembly. Driving rotation of both the driven tool and the elongated extension member while grasping the light attachment assembly when the driven tool is positioned within the target are such that the portion of the elongated extension member housed within the hollow portion of the sheath rotates relative to the light assembly. |
| US10987784B2 |
Cordless impact tool with brushless, sensorless, motor and drive
An impact tool of the present disclosure provides an impact mechanism having a hammer and an anvil, the hammer being rotatable about a first axis and to periodically impact the anvil to drive rotation of the anvil about the first axis. The electric motor includes a plurality of pole pairs of windings and a rotor that is rotatable with respect to consecutively energized pole pairs of windings. No encoder or sensor is electronically coupled to the electric motor to detect a position of at least one magnet attached to the rotor with respect to at least one pole pair when the rotor is in a stopped condition. When the rotor is in the stopped condition, the motor controller energizes the at least one pole pair to initiate rotation and detect a back EMF generated by movement of the rotor without a sensor or encoder to indicate the predetermined location of the at least one magnet attached to the rotor with respect to the at least one pole pair. |
| US10987773B2 |
Transport device for rotatably and/or linearly moving a workpiece
The invention relates to a transport device comprising a transport element for receiving a workpiece, said transport element being movable by means of a motor from a first idle position into a second idle position, the transport element being drivably connected to at least one driver that engages in a drive groove of a drum cam that can be driven by the motor, which can be controlled by means of a programmable control device on the basis of a motor control curve. The drive groove has a variable incline at least in sections and the motor control curve also has a variable course at least in sections, the movement of the transport element being generated by a simultaneous superposition of a first movement component based on a region of variable incline of the drive nut and a second movement component based on a variable region of the motor control curve. |
| US10987771B2 |
Air rest button
An air rest button system comprising a body element and a plunger element configured to accept a rest button. The plunger element generally is configured to be inserted into a base in the top of the body element. The plunger element in turn has a bore or hole therein configured to receiving an air rest button, which may be substituted for other air rest buttons, facilitating the modularity of the present system. |
| US10987770B2 |
Cartesian machine tool with horizontal slide and cantilevered machining head, and slide carriage for such machine tool
A Cartesian machine tool, of the type with a horizontal slide and a machining head supported in a cantilever manner by the slide, includes a slide carriage, with respect to which the slide can move horizontally with corresponding elements of horizontal translation, and a post, which includes two opposite guiding columns for the vertical movement of the slide carriage with elements of vertical translation. The slide carriage includes a first front part coupled to the post with the elements of vertical translation and a second rear part coupled to the first part with elements of translation in a transverse direction with respect to a direction of motion of the slide with respect to the carriage. |
| US10987769B2 |
Tooling base
A tooling base that is an improvement over current designs in the form of simplified number of parts, easier manufacturing of parts and that can be actuated for clamping and releasing a tooling fixture by pneumatic, other computer controlled means as well as manually is described. The tooling base uses clamping fixtures that are spring loaded to press cleats into recesses on alignment studs that locate and hold any variety of tooling fixtures to the base. |
| US10987768B2 |
Torque tool with latch assembly
A torque tool to apply torque to a subsea component with a remotely operated vehicle (ROV) includes a housing, a socket drive to rotate within the housing, and a latch mechanism. The latch mechanism includes a latch to move with respect to the housing between an engaged position to engage the subsea component and a disengaged position to disengage the subsea component. The latch mechanism further includes a biasing mechanism to bias the latch from the engaged position towards the disengaged position, and/or an electric motor to move the latch from the disengaged position towards the engaged position. |
| US10987766B2 |
Automated electromagnetic fastener delivery system
A fastener delivery system including a feed tube coupled to a delivery location at a second end of the feed tube. The fastener delivery system includes a fastener feed mechanism comprised of a coil wound around a coupler. The coupler is coupled to the feed tube at a first end of the feed tube. The fastener delivery system includes a fastener positioning device configured to receive a fastener. The fastener positioning device is connected to the coupler and operates to inject the fastener into the coupler. A current is applied through the coil to generate a magnetic field. The magnetic field interacts with the fastener and thereby projects the fastener through the feed tube towards the delivery location. |
| US10987761B2 |
Method of creating a burst groove by laser scoring
A method of creating a burst groove in a burst member is provided. The burst groove following a path, wherein: the groove is created in a plurality of laser scoring stages which are performed in succession to thereby successively increase the depth of the burst groove during each stage; each laser scoring stage involving laser scoring the burst member along at least a portion of the path. The laser scoring in each stage involves laser-energizing a respective region of the burst member with a respective energization width measured perpendicular to the path. In at least one stage the energization width is smaller than the energization width in the immediately preceding stage. |
| US10987759B2 |
Advanced back-strike protection process and related devices for water jet guided laser process
When water jet guided laser drilled through the first body, there is a confined embodiment between the first body and the second body. To prevent water jet guided laser to continue in this direction and create damage on the second body, a volume vibrator is connected to the embodiment and media that filled embodiment get pumped in and pumped out from the embodiment at adjustable frequency and cycle volume. Mechanical energy is then transferred into the embodiment to generate local media vibration. The laminar flowing state of the water jet is interrupted and the laser beam confined in the water jet is dispersed. Plugging method is also involved to insure when there are multiple holes on the embodiment, there will be enough mechanical energy get transferred to the laser breakthrough location. |
| US10987753B2 |
Wedge bonding tools, wedge bonding systems, and related methods
A wedge bonding tool including a body portion including a tip portion is provided. The tip portion includes a working surface configured to contact a wire material during formation of a wedge bond. A plurality of notches are defined by one or more surfaces of the body portion. |
| US10987749B2 |
Methods and systems for indicating a schedule in a welding-type torch
Systems and methods are provided for indicating schedules in welding-type torches. A welding-type system may comprise a welding-type power source, a welding-type torch, driven by the welding-type power source, and a welding-type connector configured for connecting the welding-type power source to the welding-type torch. The welding-type torch may comprise one or more indication components configured for providing, to a user of the welding-type system, indications relating to at least one of operations of the welding-type torch, status of welding-type operations, or welding-type parameters. The one or more indications comprise an indication of a present value of a particular welding-type parameter that pertains to configuration of the welding-type power source; and the one or more indication components are configured to provide the indication of present value of the particular welding-type parameter without requiring a change to structure of the welding-type connector. |
| US10987747B2 |
Brazing material outer coat and preparation method thereof, in-situ synthetic metal-coated flux-cored silver brazing material, preparation method thereof, welding method and joint body
A brazing material outer coat and a method for preparing the same, an in-situ synthetic metal-coated flux-cored silver brazing material and a method for preparing the same, a welding method and a joint body, wherein the in-situ synthetic metal-coated flux-cored silver brazing material comprises a flux core and a brazing material outer coat wrapping the flux core, the brazing material outer coat comprises, in percentage by weight: silver Ag 20.0˜36.0%, copper Cu 35.0˜45.0%, zinc Zn 27.0˜37.0%, tin Sn 1.0˜3.0%, phosphorus P 0.1%˜0.5%, nickel Ni 0.5˜2.0%, germanium Ge 0.1˜0.3%, and lithium Li 0.1˜0.3%, the flux core comprises, in percentage by weight: elemental boron micropowder 5.0˜10.0%, sodium borohydride 5.0˜10.0%, potassium fluoroborate 15.0˜30.0%, boric anhydride 25.0˜40.0%, sodium fluoride 10.0˜30.0%, sodium bifluoride 2.0˜4.0%, and copper sulfate 1.0˜5.0%. The in-situ synthetic metal-coated flux-cored silver brazing material in the present disclosure realizes self-reaction in a brazing process to coat a layer of copper film on a surface of a brazed metal, the core of the brazing material has good wettability, good flowability, self-brazing function, and zinc being hard to volatilize, the flux coat has high activity, low hygroscopicity, few carbon residues, good plasticity and toughness, etc. The present disclosure is particularly suitable for brazing pipeline components of stainless steel, manganese brass and so on. |
| US10987740B2 |
Cutting insert having land with spaced apart upwardly bulging land portions and non-rotary cutting tool provided therewith
A cutting insert has a cutting portion corner formed at the intersection of a rake surface, a forward cutting portion surface and a relief surface. A cutting edge is formed at an intersection of the rake surface and the relief surface with a land that is located on the rake surface and that extends along, and negatively away from, the cutting edge. A chip-control arrangement is located at the rake surface and includes an elongated projection and plurality of spaced apart elongated protuberances that extend from the projection to the cutting edge, so that the land has a plurality of spaced apart bulging land portions. A non-rotary cutting tool has an insert holder having an insert pocket and the cutting insert releasably retained therein. |
| US10987739B2 |
Cemented carbide and cutting tool
Provided are a cemented carbide having excellent plastic deformation resistance and a cutting tool in which the cemented carbide is used as a substrate. A cemented carbide includes a hard phase containing tungsten carbide particles and a binder phase containing, as a main component, an iron-group element, wherein the formula B/A≤0.05 is satisfied, where A represents the number of the tungsten carbide particles, and B represents the number of tungsten carbide particles whose number of contact points with other tungsten carbide particles is 1 or less. Preferably, the iron-group element includes cobalt, and the cobalt content in the cemented carbide is 8% by mass or more. Preferably, the tungsten carbide particles have an average particle diameter of 3 μm or more. |
| US10987738B2 |
Surface-coated cutting tool
A surface-coated cutting tool includes a substrate and a coating that is disposed on the substrate and formed so as to cover at least a portion of a flank face, in which the coating includes an inner layer and an outer layer formed on the inner layer, the inner layer is formed of at least one layer and includes an aluminum oxide layer as a layer in contact with the outer layer, the outer layer has a multilayer structure that includes three or more layers stacked on top of one another, and each of the layers that constitute the multilayer structure contains titanium. |
| US10987736B2 |
Article
An article includes a substrate and a structure including direct metal laser melted material of predetermined thickness attached to the substrate, the structure formed by providing and depositing a metal alloy powder to form an initial layer having a preselected thickness and shape including at least one aperture, melting the metal alloy powder with a focused energy source, transforming the powder layer to a sheet of metal alloy, sequentially depositing an additional layer of the metal alloy powder over the sheet of metal alloy, the additional preselected shape including an aperture corresponding to the aperture in the initial layer, and melting each additional layer of the metal alloy powder with the focused energy source, increasing the thickness of the sheet and forming at least one aperture having a predetermined profile, the article further including a passageway through the structure including the aperture and a corresponding metering hole. |
| US10987725B2 |
Decompression kneader
Provided is a decompression kneader capable of stabilizing a moisture content of resultant kneaded sand. The decompression kneader includes a kneader main body configured to knead casting sand and water, a decompression pump configured to reduce a pressure inside the kneader main body, a condenser configured to condense water vapor sucked by the decompression pump, a tank configured to store water condensed by the condenser, and a supply amount calculation apparatus configured to calculate an amount of water supplied from the tank to the kneader main body. The tank comprises a water gauge and a weighing scale, and the supply amount calculation apparatus estimates an amount of the casting sand contained in the tank based on measured values of the water gauge and the weighing scale and corrects the amount of the water supplied from the tank with reference to the amount of the casting sand. |
| US10987724B2 |
Sand mold shaping material, and method for shaping sand mold using same
A sand mold shaping material contains an aggregate comprising inorganic particles, and microcapsules enclosing a binder which causes the aggregate to bind. The binder is a liquid binder that is in a liquid phase at room temperature, and is enclosed in an outer shell comprising a resin that forms the microcapsule. The sand mold shaping material is in a dry state when used to fill a molding die for shaping. |
| US10987722B2 |
Die changer with removable die adapted thereto and die dome as well as method for removing and inserting the removable die
A removable die of a joining tool comprising a die head having an upper side, a bottom side and a die shaft extending from the bottom side and receivable and lockable in a die dome without rotation. The die shaft comprises: at least one first radial web forming an axial undercut on two sides by which the die shaft is lockable in the die dome by a linear inserting movement, at least one second exposed radial web, the radial length of which is adaptable to a diameter of the die dome to ensure a lateral guiding of the die shaft in the die dome and which is arranged between the die head and the first radial web, and an ejection surface by which the removable die can be moved out of the die dome and which is arranged at the free end of the die shaft opposite to the die head. |
| US10987720B2 |
Fluid circulation tube and a heat exchanger comprising such tubes
Fluid circulation tube and heat exchanger equipped with tubes of this type are disclosed. The tube (6) is produced by bending, and, once its wall has been bent, has a base portion (12) prolonged laterally by two linking portions (13) leading to two top portions (14) turned toward one another, which terminate in end legs (15) turned toward the base portion (12), forming at least two parallel longitudinal internal channels (16) into which the two systems (20) of bends (21) of a corrugated disrupter (17) can be inserted, these systems being interconnected by a central part (23) inserted into a gap left between said legs and the base portion. |
| US10987718B2 |
Method for production of a supporting member and a ladder frame or box frame
The present invention concerns a method for production of a supporting member with an at least partially closed cross-section, having at least a first metal shell and a second metal shell which are connected together at least in portions in the longitudinal direction. The method includes a provision of at least a first and a second metal blank. At least a first and a second metal shell are produced from the respective first and second metal blanks. The first and second metal shells each have at least one floor with two protruding uprights spaced apart from each other and integrally connected to the floor. The first and second metal shells are positioned such that the uprights of the metal shells come into overlapping contact. |
| US10987716B2 |
Press die
A press die includes a fixed die, a first movable die, and a second movable die to cut out a product from a metal plate member, and a scrap cutter to cut scrap that is not part of the product. A fixed-die cutting blade of the fixed die is configured to have a fixed-die cutting blade relief portion formed near a base end of the protruding scrap cutter and recessed inward to the product side from the cutting line of the product. The fixed-die cutting blade relief portion includes a substantially arc-shaped cross-sectional portion corresponding to a machining radius of a machining tool for forming the scrap cutter. A first movable-die cutting blade of the first movable die has a movable-die cutting blade protrusion to cut the metal plate member inward to the product side from the cutting line of the product. |
| US10987715B2 |
Tool storage system, production plant and method for manipulating with such a tool storage system
The invention relates to a tool storage system (32) as well as to a production facility (1) for free-form bending of workpieces (2) made from a metal sheet, by means of a bending press (3), comprising a tool storage unit (30), a tool manipulation unit (31), and a provisioning unit (55) having provisioning rails (56, 57). The tool storage unit (30) has an upper and lower storage rail (34, 35), which are disposed spaced apart from one another at a vertical distance, as well as locally fixed in place relative to one another. The tool manipulation unit (31) has tool manipulation devices (36, 37), wherein each of the same comprises a working rail (38, 42), an auxiliary rail (39, 43), a drawing-in device (40, 44), as well as a pushing-out device (41, 45). Each of the tool manipulation devices (36, 37) can be displaced laterally next to the storage rails (34, 35), along a longitudinal guide arrangement (46, 47). Furthermore, the invention also comprises a method for manipulation of at least one bending tool (4) in such a tool storage system (32). |
| US10987713B2 |
Device and method for straightening pressing of a flat metal product
A horizontal roll stand includes upper and lower back-up rolls, removable work rolls, a balancing device for supporting the upper work roll, and a vertical adjustment device for the lower back-up roll. The work rolls are removed and a press device for straightening pressing of a flat metal product is inserted into the roll stand. The press device includes opposing upper and lower press frames that are displaceable relative to each other. The upper press frame and the lower press frame have one of a selectively moveable pressing die or opposing selectively moveable table with a trough for immersion of the pressing die to selectively press and flatten defects in the flat metal product. The upper press frame includes carrier elements which contact a balancing device of and for support within the roll stand. The lower press frame has support elements for being supported on stanchions of the roll stand. |
| US10987712B2 |
Tubular element to transfer abrasive materials, in particular concrete, and method to make it
A method to make a tubular element to transfer abrasive materials such as concrete, inert materials or suchlike, where the tubular element includes an external tubular component made of steel and an internal tubular component, coaxial to the external tubular component, where the internal tubular component is made of chromium carbide, or other similar material resistant to wear. |
| US10987711B2 |
Roll straightening machine and method for producing an elongated string member
A roll straightening machine for straightening an elongated string member includes at least one first straightening roll rotatably mounted around a first rotation axis, and at least one second straightening roll rotatably mounted around a second rotation axis. The first and second rotation axis and rolls are oblique with respect to a longitudinal axis of an elongated string member to be received in the roll straightening machine, and also oblique with respect to one another. In order to provide a roll straightening machine that can be set up flexibly for different requirement profiles, the first rotation axis is mounted on a first holding device and the second rotation axis is mounted on a second holding device. The first and the second holding devices are supported by a frame in a removable manner, which is arranged to receive a variable number of holding devices having the straightening rolls. |
| US10987699B2 |
Density separator for waste material
The separator according to the invention comprises: a tank (1) for receiving waste material and containing fluid to separate waste material by density into floating and settled material; automatic feed means (18, 37), for example, a double screen (18) to feed waste material to the tank (1); motorised conveyor belts (3, 4) divided into a floating waste material conveyor (3) and a settled waste material conveyor (4) to extract floating or settled waste material from the tank (1): and a blower-type sorting device (21) comprising: a turbine (22) that provides an airflow; and a branched duct (23) divided into: a riser duct (26) to transport part of the airflow to a diffuser (39) beneath the automatic feed means (18, 37) to raise light-weight waste material; and a discharge duct (27) to transport and horizontally expel another part of the airflow in order to remove previously raised waste material. The separator according to the invention may incorporate bubble-making means, with injectors (2) to facilitate floatability and remove floating waste material. |
| US10987696B2 |
Acid-reducing beverage filter and method of producing same
The present technology provides a method for preparing an acid-reducing filter that includes depositing a mineral blend layer to a filter substrate, where the mineral blend layer comprises calcium carbonate and magnesium carbonate at a weight ratio of about 1:10 to about 10:1, the mineral blend is free of soluble halide or hydroxide salts of alkali or alkaline earth metals, and the mineral blend layer is insoluble in water. |
| US10987692B2 |
Cleaning device
Provided is a cleaning device, comprising a wiper, a first clamping plate, a second clamping plate, a first elastic clamp and a second elastic clamp. The first clamping plate comprises a first plate body, a first bent portion and a first end portion. The first bent portion extends between the first plate body and the first end portion in a bent manner. The second clamping plate comprises a second plate body, a second bent portion and a second end portion. The second bent portion extends between the second plate body and the second end portion in a bent manner. The wiper is positioned between the first clamping plate and the second clamping plate. The cleaning device is moved relative to the nozzle to wipe the nozzle for cleaning. The wiper will not generate pollution and basically causes no wear to the nozzle. |
| US10987690B2 |
Manually-operated paint spray gun
A manually-operated paint spray gun includes a body having a nozzle for atomizing paint to be sprayed and a handle forming a handgrip and provided with a connector for the inflow of compressed air to be supplied to the nozzle, wherein the handle of the gun has a compressed air regulator operatively associated to which is a pressure sensor at least part of which is arranged in a removable portion of the handle forming a substantial part of the dorsal area of the handgrip and is separated from the inflow connector. |
| US10987685B2 |
Spray application system components comprising a repellent surface and methods
Presently described are components of a spray application system. At least one component comprises a liquid repellent surface layer. The liquid repellent surface (e.g. layer) may comprise a porous layer and a lubricant impregnated into pores of the porous layer; a fluoropolymer; a fluorochemical material and an organic polymeric binder; or a fluorochemical material melt additive and a thermoplastic polymeric material component. The component is typically a liquid reservoir, a liquid reservoir liner, a lid for a liquid reservoir or liner, or a combination thereof. In some embodiments, the component comprises a thermoplastic polymeric material. In some favored embodiments, the component is a removable liquid reservoir or liner. In some favored embodiments, the component is a collapsible liquid reservoir or liner. The spray application system typically further comprises a gravity-fed spray gun. Also described are spray application systems, methods of using a spray application system, as well as methods of making a component of a spray application system wherein the component has a liquid repellent surface. |
| US10987680B2 |
Spray head with hyperboloid spray pattern
A spray head for directing water into a spray pattern that includes a casing configured to receive a supply of water and a plurality of nozzles disposed on the casing with each nozzle being configured to emit water in a stream away from the casing. The plurality of streams of water from the plurality of nozzles are configured to form a hyperboloidal shaped spray pattern. |
| US10987677B2 |
Flotation performance enhancement
Flotation separation apparatus and methods are described herein, comprising a vessel having a plurality of flow guides oriented vertically in the vessel, a liquid inlet at a lower part of the vessel, a gas inlet at the lower part of the vessel, a first liquid outlet at an upper part of the vessel, a second liquid outlet at the lower part of the vessel, and a gas outlet at the upper part of the vessel. |
| US10987676B2 |
High efficiency conical mills
Screens for conical mills and an improved gearbox and housing for such conical mills are shown and described. The screens are frusto-conically-shaped and include a tapered sidewall with a plurality of openings in the sidewall that may be of uniform size. Each opening is separated from adjacent openings by spacing distances which are shorter at the top of the tapered sidewall and longer at the bottom of the tapered sidewall to thereby reduce the residence time of the powder being milled at the top of the tapered sidewall and to increase the residence time of the powder being milled at the bottom of the tapered sidewall. |
| US10987670B2 |
Electrode array for vortex-assisted electroporation
A device includes a microfluidic trap disposed along a microfluidic channel, the trap and channel having dimensions to create a fluid vortex within the trap to trap a particle of interest and an electrode having interdigitated electrically isolated fingers positioned in the trap to create an electric field across the trap such that the electric field causes electroporation of a molecule into the particle of interest. A further device includes an array of channels, traps and interdigitated electrically isolated fingers. |
| US10987669B2 |
Apparatus and method for detection of tumour cells and circulating tumour cells
The invention relates to an apparatus and method of detecting and quantifying the number of circulating tumour cells (CTCs) and/or tumour cells (TCs) from a liquid biopsy by using a hyperoxic environment and incubation with a fluorophore-labelled metabolic indicator (fluorophore-labelled 2-D-glucose derivative) and microfluidic chips. |
| US10987668B2 |
Test card with well shelf
Provided herein are a test card, method of manufacturing the same, and mold for manufacturing the same. The test card may include a body and a well. The body may include a first surface and a second surface opposite the first surface. The well may define an opening extending from the first surface to the second surface and configured to receive a sample therein. The well may further include a shelf extending into the opening, such that the opening is narrower between the shelf and the second surface than between the shelf and the first surface. |
| US10987667B2 |
Flow control system for diagnostic assay system
A disposable cartridge for mitigating cross-contamination of fluid sample reagents. The disposable cartridge includes a cartridge body defining a syringe barrel having an barrel port operative to inject and withdraw assay fluids in response to the displacement of a syringe plunger. Furthermore, the disposable cartridge includes a rotor defining a plurality of assay chambers in fluid communication with the barrel port through one of a plurality of rotor ports disposed about the periphery of the rotor. Finally, the disposable cartridge includes a flow control system between the barrel and rotor ports which prevents cross-contamination of fluid sample reagents from one assay chamber to another assay chamber. |
| US10987666B2 |
Metering apparatus
A metering apparatus including a scale on which a metering head is disposed in such a manner that the scale measures the weight of the metering head, and a metering tool for taking up and dispensing substance, attached to the metering head. The metering tool is configured as a glass tubule having a glass punch slidably disposed therein, forming a seal. The metering head is provided with a first gripping tool for clamping the glass tubule in place and with a second gripping tool for clamping the glass punch in place. The metering head furthermore has a raising and lowering device for raising and lowering the second gripping tool relative to the first gripping tool, such that the glass punch can be raised and lowered in the glass tubule of the metering tool. |
| US10987663B2 |
Method for preparing laminar zinc hydroxide organic-inorganic nanocomposites for use in the removal and degradation of dyes from textile effluents
The present invention relates to a method for removing dyes from textile effluents and other organic substances using nanocomposites based on zinc hydroxides and carboxylic acids capable of adsorbing and degrading. More specifically, the present invention consists of a method to generate new zinc hydroxide-based materials, which allows removal and degradation of methylene blue and other organic compounds from wastewater from industrial effluents, particularly those from textile industry. |
| US10987661B2 |
Alloyed zeolite catalyst component, method for making and catalytic application thereof
The presently disclosed and claimed inventive concept(s) generally relates to a method of making a solid catalyst component comprising a zeolite with a modifier and at least one Group VIII metal alloyed with at least one transition metal and a process of converting mixed waste plastics into low molecular weight organic compounds using the solid catalyst component. The process of converting mixed waste plastics into low molecular weight organic compounds may employ the use of a non-thermal catalytic plasma reactor, which may be configured as a fluid bed reactor or fixed bed reactor. |
| US10987660B2 |
Hexaaluminate-comprising catalyst for the reforming of hydrocarbons and a reforming process
A hexaaluminate-containing catalyst containing a hexaaluminate-containing phase which includes cobalt and at least one further element of La, Ba or Sr. The catalyst contains 2 to 15 mol % Co, 70 to 90 mol % Al, and 2 to 25 mol % of the further element of La, Ba or Sr. In addition to the hexaaluminate-containing phase, the catalyst can include 0 to 50% by weight of an oxidic secondary phase. The process of preparing the catalyst includes contacting an aluminum oxide source with cobalt species and at least with an element from the group of La, Ba and Sr. The molded and dried material is preferably calcined at a temperature greater than or equal to 800° C. In the reforming process for reacting hydrocarbons in the presence of CO2, the catalyst is used at a process temperature of greater than 700° C., with the process pressure being greater than 5 bar. |
| US10987657B1 |
Gold supported yttrium oxide nanorods and methods of use thereof
A catalyst comprising Y2O3 nanorods and gold nanoparticles dispersed on a surface of the nanorods is provided. The gold is present at a concentration of 0.5-2 wt %. A method of forming olefins by oxidative cracking is also provided. The method includes reacting an alkane with a reactant gas mixture in the presence of a catalyst under conditions suitable for forming light olefins (ethtylene and propylene). |
| US10987655B2 |
Molybdenum-vanadium bimetallic oxide catalyst and its application in chemical looping oxidative dehydrogenation of alkane
A molybdenum-vanadium bimetal oxide catalyst having a molecular formula of Mo1Vy, where y represents an atomic molar ratio of vanadium and molybdenum. An oxygen support Mo1Vy is prepared by an impregnation method including impregnation, drying, calcination, and tablet pressing. In the dehydrogenation reaction of a light alkane to an alkene over the supported molybdenum-vanadium bimetal oxide, the reaction temperature is 450° C.-550° C. Propane can be oxidized and dehydrogenated to produce propylene with a high activity and high selectivity. A conversion rate of propane remains at 30%-40%, and a selectivity for propylene is 80%-90%. A fresh oxygen support changes from a high-valence state to a low-valence state after reacting with propane. A low-valence state oxygen support reacts with air or oxygen to be oxidized to a high-valence state, and recovers lattice oxygen and cycles again. |
| US10987652B2 |
Gas absorption material, use of same for gas absorption, gas absorption body, gas absorption method, acidic gas absorption device, acidic gas recovery device, water vapor absorption device, water vapor recovery device, heat exchanger, and heat recovery device
A gel particle film of amino group-having polymer compound particles has a large acid gas absorption amount and desorption amount per unit volume, and has a high acid gas absorption rate and desorption rate per unit mass, and further has high stability. A gas absorber having the gel particle film supported on a carrier is useful as an acid gas separation material having good energy efficiency. |
| US10987644B2 |
Fluid dispersing device and heat treatment device
A fluid dispersing device includes a tubular first wall portion with an axis extending in a first direction defined as a central axis, and a second wall portion separated downward from the first wall portion. The second wall portion includes at least one circular member and a disk-like member each having a flat surface for causing a fluid passing through an inner space of the first wall portion to collide therewith. The disk-like member is separated downward from the at least one circular member. The at least one circular member has an outer diameter equal to or smaller than an inner diameter of the first wall portion. The disk-like member has an outer diameter equal to or smaller than an outer diameter of the closest circular member. |
| US10987637B2 |
DDR-type zeolite seed crystal and method for manufacturing DDR-type zeolite membrane
A DDR-type zeolite seed crystal has an average particle diameter of less than or equal to 0.2 μm, and an average aspect ratio of less than or equal to 1.3. |
| US10987636B2 |
Filtration systems and methods for manufacturing biologically-produced products
Aspects of the present disclosure relate to filtration systems and methods for production of biologically-produced products, which may include pharmaceutical and/or protein products. Certain biomanufacturing systems described herein comprise a bioreactor (e.g., a perfusion bioreactor, a chemostat) and a filter probe comprising a filter bundle comprising a plurality of hollow fibers (e.g., longitudinally aligned hollow fibers). According to some embodiments, a center-to-center distance between any two hollow fibers within the fiber bundle at one or more points along a length of the fiber bundle is relatively large (e.g., greater than or equal to an average outer diameter of the hollow fibers of the fiber bundle, greater than or equal to 1.1 times a minimum diameter of the two hollow fibers). In some embodiments, the hollow fibers within the fiber bundle are arranged in an array (e.g., a hexagonal, linear, annular, or square array). |
| US10987632B2 |
Spiral membrane element
A spiral membrane element is provided which has a restricted outer diameter but is heightened in effective membrane area, and further which can be decreased in operation energy therefor. The spiral membrane element is an element including plural membrane leaves L in each of which a permeation-side flow-channel member 3 is interposed between opposed separation membranes 1; a supply-side flow-channel member 2 interposed between any two of the membrane leaves L; a perforated central pipe 5 on which the membrane leaves L and the supply-side flow-channel member 2 are wound; and sealing parts that prevent a supply-side flow-channel from being mixed with a permeation-side flow-channel. The sealing parts include both-end sealing parts 11 in which an adhesive is used to seal two-side end parts of each of the membrane leaves L on both sides of the leaf in an axial direction A1 of the leaf. The thickness T1 of the both-end sealing parts 11 is 390 to 540 μm. |
| US10987628B2 |
Water control in dielectric fluid layers
A system and method are described for regulating water concentration in a dielectric fluid. The system can comprise electrodes capable of applying an electric field across the dielectric fluid, thereby causing charge carriers and water included in the charge carriers to move toward a respective electrode. The system further includes a trap positioned near the electrodes and comprising a water absorbing material capable of trapping water, thereby reducing the concentration of water in the dielectric fluid. It is also possible to measure properties of the dielectric fluid and use such measurements to control the water-trapping process. |
| US10987627B2 |
Reducing the emission of nitrogen oxide when starting up systems for producing nitric acid
A method of reducing NOx in tail gas obtained during startup of a plant for preparing nitric acid may involve heating the tail gas from a starting temperature T0, through a threshold temperature TG, to an operating temperature TB at which steady-state operation of the plant can occur (T0 |
| US10987616B2 |
Tumbler systems and methods
A tumbler may be used as defluidizer, dryer, coater, classifier, or dynamic filter. The tumbler includes a rotatable drum that receives a solid/fluid slurry through an inlet chute. As the slurry travels through the drum, fluid exits the drum through a plurality of apertures in screens attached to the sides of the drum, while the solids continue along the drum's length until they reach one or more openings and exit the drum into an outlet chute. The outlet chute includes ridges that wrap around rings extending from the openings of the drum to prevent solids from escaping the outlet chute. To further dry the solids before they exit the drum, an air tube at least partially disposed within the drum is configured to introduce a flow of air into the drum. |
| US10987615B2 |
Manifold assembly and method of use
A manifold assembly including a linear guide and a method of engaging a filter capsule in the manifold assembly are provided. |
| US10987608B2 |
Liquid-distilling device
A liquid distiller device. The device includes a dome impermeable to steam, configured to host the liquid to be distilled in an inferior part of its volume; a heat pump arranged in the interior of the dome and provided with a condenser which releases heat and an evaporator which absorbs heat, respectively conforming a hot part and a cold part of the heat pump; a radiator connected to the hot part of the heat pump, suitable for evaporating the liquid to be distilled; a condenser deposit connected to the cold part of the heat pump and suitable for condensing the evaporated liquid and collecting the distillate and; a collector tube, connected to the condenser deposit for the exit of the distillate. |
| US10987602B1 |
Weight device for model car
The present invention provides a weight device for a model car attached to an outer periphery of a wheel of the model car, the weight device having: an annular case extended along a circumferential direction of the wheel, the annular case having an annular internal space; and a plurality of weight members arranged in the annular internal space. The weight members are configured to be relatively movable in the circumferential direction with respect to the annular case when the annular case is rotated in the circumferential direction, and the annular case is attached to the outer periphery of the wheel so that the wheel is idly rotatable with respect to the annular case. |
| US10987599B1 |
Inflatable or injectable toy device
An inflatable toy device is disclosed, the toy including a base portion, the base portion having an inlet and an outlet, the outlet covered by a removable surface; an inflatable object disposed within the base portion when not inflated, the inflatable object being fluidly connected to the inlet; a hand pump fluidly connected to the inlet, the hand pump configured to create air pressure to inflate the inflatable object; wherein the inflatable object protrudes from the base portion outlet, thereby removing the removable surface, upon inflation. The toy device also may include an injectable object fluidly filled such that the injectable object protrudes from the base portion outlet upon being filled. |
| US10987594B2 |
Systems and methods to elicit physical activity in users acting as caretakers of physical objects
Systems and methods to elicit physical activity in users acting as caretakers of physical objects. Caretaking information for a physical object may define a set of caretaking criteria of a physical object. Individual caretaking criteria may comprise one or more caretaking requirements of the physical object to be satisfied based on physical activity of a user. The caretaking requirements of the physical object may “trick” the user into performing fitness/wellness behavior. In caring for the physical object, the user may actually be caring for themselves. |
| US10987592B1 |
Systems and methods to correlate user behavior patterns within an online game with psychological attributes of users
Systems and methods to correlate user behavior patterns within an online game with psychological attributes of users exhibiting the user behavior patterns are disclosed. Exemplary implementations may: store user information associated with the individual users including assignments of the individual users to individual ones of different cohorts of users, wherein the different cohorts are associated with different psychological profiles, where a given psychological profile is defined by multiple psychological parameter values, and the users are assigned to the different cohorts based on the psychological parameter values; obtain performance information that characterizes performances of user behavior patterns by the individual users; and determine correlations between individual ones of the performances of the user behavior patterns and individual ones of the psychological parameters based on the obtained user behavior patterns, the assignments of the users to the cohorts, and commonalities in the psychological profiles of the users within the individual cohorts. |
| US10987591B2 |
Method of synchronizing online game, and server device
The present disclosure provides a method of synchronizing an online game, and a server device, that do not require centralized information management, reduce the processing burden on each device during online communication, and allow for continuation of processing in an offline environment. A method, according to the present disclosure, of synchronizing an online game that allows for transmission and reception of information related to game processing between a first client terminal and a second client terminal via a server includes: receiving, from the first client terminal connected online, first information related to game processing on the first client terminal; determining whether the first information is information that determines a game status; and storing the first information on the server and transmitting the first information to the second client terminal when the first information is determined to be information that determines the game status. |
| US10987589B2 |
Systems and methods for determining game level attributes based on player skill level prior to game play in the level
A system, a machine-readable storage medium storing instructions, and a computer-implemented method are described herein for a System Tuner for customizing a player's experience. The System Tuner calculates a player skill level for a player. The System Tuner modifies at least one attribute of a second game level based on the player skill level prior to game play of the player in the second game level. The System Tuner detects game play of the player in the second game level. The System Tuner identifies a difference between a current rate of progression of the player and a reference rate of progression. The System Tuner triggers the modified attribute of the second game according to an extent of the difference between the current rate of progression and the reference rate of progression. |
| US10987588B2 |
System and method for optimizing virtual games
The present specification describes an assistive tool that facilitates the design of video games to achieve a true randomized, non-biased and neutral gaming environment that is bounded so that extremes of disincentives and excess incentives are avoided. In one embodiment, the tool allows for simulation of game environment and generates variables that enable reward acquisition by players. In one embodiment, the tool allows the game systems to be defined in such a way that an agent, such as an artificial player implemented by a computer program, can interact with the game environment. In one embodiment, the present tool uses generative models driven by data from previous versions of a game to define the behavior of such agents in simulated games. |
| US10987581B2 |
System and method for rotating drop rates in a mystery box
A system and method configured to enhance gameplay between users in an online game and to provide enhanced interest in virtual goods associated with collections of virtual goods through the ability to rotate drop rates associated with these virtual goods from time to time. The system and method includes the provision of functionality which allows providers of online games to periodically rotate drop rates associated with mystery boxes in order to maintain and/or generate additional interest in specific mystery boxes. As a result, it is possible for game operators to enhance revenue opportunities associated with these boxes even in the case where such boxes have been available for a relatively lengthy period of time and/or where players would have otherwise lost interest in specific boxes. |
| US10987579B1 |
2.5D graphics rendering system
A graphics rendering system is disclosed for generating and streaming graphics data of a 3D environment from a server for rendering on a client in 2.5D. 2D textures can be transmitted in advance of frames showing the textures. Data transmitted for each frame can include 2D vertex positions of 2D meshes and depth data. The 2D vertex positions can be positions on a 2D projection as seen from a viewpoint within the 3D environment. Data for each frame can include changes to vertex positions and/or depth data. A prediction system can be used to predict when new objects will be displayed, and textures of those new objects can be transmitted in advance. |
| US10987578B2 |
Live video game intervention
A system and method for establishing a gaming session via cloud services with a first device, receiving information at the first device to establish a connection with a second device, and receiving at the first device instructions from the second device via the connection, wherein the instructions control an aspect of the gaming session. |
| US10987572B2 |
Information processing system, storage medium storing information processing program, information processing apparatus, and information processing method
A first sensor detects a movement of a first apparatus attached to a lower body of a user, and a second sensor detects a movement of a second apparatus attached to an upper body of the user or held by a hand of the user. Then, a virtual object is caused to continue a first action in a virtual space while received outputs from the first sensor and the second sensor both satisfy a condition. |
| US10987571B2 |
Puzzle with conductive path
System and method for additional amusement, entertaining and surprising visual or audible reward provided upon completing the reconstructing of a two-dimensional or three-dimensional jigsaw puzzle. The puzzle pieces include conductive pads connected by a conductor such as a wire, a metallic strip or a conductive paint, so that upon assembling the puzzle, the pads are in contact to form a continuous conductive path. The frame or the puzzle pieces include a battery (or an AC adapter) and a visual or audible signaling device operating upon sensing the continuity of the conductive path. Each of the puzzle pieces may include three or more conductive pads, allowing for the forming two or more isolated or connected distinct conductive paths. The conductive path can further affect a time measurement and its related display for timing the puzzle solving. |
| US10987569B2 |
Playing card
The present disclosure relates to a playing card, where a suit and a rank are printed on one surface of a card base sheet, a back pattern is printed on a back surface, an intermediate layer having a black layer or a color layer similar to black is provided on the card base sheet to make transmission of visible rays difficult, and ink containing no carbon is used for printing the suit and the rank. The intermediate layer is configured to prevent transmission of visible rays from the back surface. The suit and the rank printed with the ink containing no carbon are configured to transmit infrared rays. The intermediate layer and the suit and rank printed with the ink containing no carbon are configured such that it is difficult for both the visible rays and the infrared rays to distinguish the suit and the rank from the back surface. |
| US10987565B2 |
Exercise machine emergency motor stop
A safety signal is sent to a relay coupled to a plurality of power leads of a motor wherein a default state of the relay is to short the plurality of power leads together and wherein the safety signal maintains the relay in an open state. The safety signal to the relay is deasserted in response to a determination that an unsafe condition has occurred. |
| US10987563B2 |
Batting training device
A batting training device is disclosed that incorporates a ball arranged secured in an aerial position in order to be batted; has a column, wherein a tube is incorporated, arranged vertically with axial freedom of movement, an elastic cord passing through the tube, the lower end of which is fastened to the lower end of the tube, while the ball is fastened at the upper end of the elastic cord. The ball rests on the upper end of the tube. The tube is made up of segments, each segment provided on the outside with a guide slot with respect to a rod, has a bend that communicates with the slot of the adjacent segment, except for in the last lower segment, wherein the bend in the corresponding slot communicates with a return channel running along the entire length of the tube and communicates with the slot of the upper segment. |
| US10987560B2 |
Swing training device, system and method
A swing training device is provided. The swing training device embodies a mask adapted to place an aperture at a predefined focal length in front of the eyes of the athlete. The mask is adapted to attach to various headgear. The mask provides guides for selectively retaining diaphragms with their own diaphragmatic apertures over the aperture. |
| US10987554B2 |
Golf club
A golf club includes a head; a shaft; a grip; and a weight member that is located in a butt end region. The grip and the weight member constitute a grip-weight portion. The shaft, the grip, and the weight member constitute a shaft-grip-weight portion. The head has a weight of greater than or equal to 195 g. The grip-weight portion has a weight of greater than or equal to 40 g. The shaft has a weight of less than or equal to 40 g. The golf club has a weight of greater than or equal to 275 g and less than or equal to 300 g. W1/W3 is greater than or equal to 0.40, where W1 represents a weight (g) of the butt end region, and W3 represents a weight (g) of the shaft-grip-weight portion. |
| US10987546B2 |
Hydrodynamic human-powered propulsion mechanism
One embodiment of improved swim fins consists of a right foot attachment (101) with an outer right blade (111) and an inner right blade (112) which is arranged such that it does not mechanically interfere with an inner left blade (113). The blades may include a pivot mechanism (220) that allows the blades to maintain an optimal angle of attack as the swimmer moves their legs up and down. In another embodiment, a right blade (1011) and a left blade (1013) are attached to the feet of a person who is propelled by the blades above the surface of the water as they pump their feet up and down, forming a human-powered hydrofoil. Other embodiments are described and shown. |
| US10987539B1 |
Climbing exercise apparatus
An exercise apparatus having homolateral and contralateral modes of operation is disclosed. The exercise apparatus may include a frame supporting generally vertically oriented reciprocating members spaced apart and in substantial parallel relationship to one another. The reciprocating members may include foot supports fixedly secured at the lower distal ends thereof and handlebars rotatably mounted proximate the upper distal ends of the reciprocating members. The handlebars may be selectively locked for homolateral and contralateral operation of the exercise apparatus. |
| US10987536B2 |
Planking exercise belt
A planking exercise belt assists the user in performing a planking exercise regimen by alerting the user when a proper plank position is not maintained during performance of the regimen. The planking exercise belt includes a belt that is adjustably secured about the user's lower torso and waist. An adjustable strap interconnects the belt and a weight. A connector is provided on the belt to removably attach the strap to the belt. When a user droops or does not engage their core muscle groups, a tension in the strap is relieved to alert the user to the poor form in performing the exercise. When the user elevates their buttocks, the weight elevates from the ground to alert the user of this improper form. |
| US10987533B2 |
Play structure clamp and system
A climbing structure is provided. The climbing structure comprises a first support post and a second support post. The climbing structure also comprises a panel with a first and second connection point. The climbing structure also has a first clamp, configured to couple the panel to the first support post at the first connection point. The climbing structure also has a second clamp, configured to couple the panel to the second support post at the first connection point. The first connection point is on a first connection plane. The second connection point is on a second connection plane. The first and second connection planes are offset from each other. |
| US10987532B2 |
Body coach
The present invention generally concerns an exercise frame. More specifically, a frame, named the Body Coach, includes a base with both wheeled and un-wheeled stabilizers, two pivoting posts, and extending slats having dip handles and pullup bar holders. The frame is small and mimics heights normal to larger caged stations in gyms, which provide a greater natural resistance for calisthenics. Retractable slats, telescopically housed in each post, extend a pullup bar upward at heights up to 7.00′. An A/R band rests in a space between the two posts. Both the band's tautness and its vertical placement within the space, relative to the extended height of the pullup bar, are adjustable. Each post pivots downward for easy storage, but, in use, the frame is sturdy, centered, and reconfigures to a user's specific height and range of motion for unmanned assistance or resistance training. |
| US10987529B2 |
Fire extinguisher
A fire extinguisher is shown and described. The fire extinguisher may include a housing, a vessel positioned within the housing, the vessel retaining a fire suppression agent therein, and a discharge port positioned in the housing and operatively coupled with the vessel, where the fire suppression agent is capable of being expelled from the discharge port. The fire extinguisher may include an electrical connector positioned on the housing, the electrical connector capable of operatively securing to an electrical outlet, where the electrical connector is rotatable relative to the housing. |
| US10987524B2 |
Interstitial ultrasonic disposable applicator and method for tissue thermal conformal volume ablation and monitoring the same
An interstitial ultrasound thermal ablation applicator for conformal treatment of an inhomogeneous tumor lesion includes: a body having a longitudinal axis; and a plurality of array transducers mounted on the body, arranged side by side and having azimuth directions parallel to the longitudinal axis of the body, and having outer faces disposed in a polygonal arrangement; the plurality of array transducers having predetermined elevation dimensions defined for directing emitted ultrasonic energy to obtain a conformal volume treatment of the tumor lesions. An electronic driving method for driving an applicator having multiple independent transducer elements arranged in rows and columns includes: controlling focal parameters of each row and column of transducer elements; and controlling a contribution of each row and column of transducer elements in a manner to provide a conformal ablated volume. |
| US10987521B1 |
System and methods for treating brain related conditions with photobiomodulation therapy
Photobiomodulation or low level light therapy is applied to the brain using a treatment protocol that shows improvement in treating a number of disease states and injuries of the brain. A laser probe including an LED cluster is placed perpendicular to the skull at a plurality of identified treatment points on the patient's skull for durations of 1 minute with pulsed waveforms at each location. The pattern for the treatment points varies by disease or injury state being treated. The treatment period is typically on nonconsecutive days for 6 weeks (3 times per week) or 9 weeks (2 times per week) per treatment protocol. Patients with Parkinson's disease, Alzheimer's disease, balance issues, concussions, depression, strokes, and other brain diseases or injuries have shown dramatic improvement under such treatment protocols. |
| US10987515B2 |
Management of electrical stimulation therapy
The techniques of the disclosure describe example medical devices, systems, and methods for delivering electrical stimulation therapy to a patient. In one example, a medical device selects subsets of a plurality of therapy parameter sets that define electrical stimulation therapy, each subset including at least one therapy parameter set and less than all of the therapy parameter sets. Further, the medical device delivers, via a plurality of electrodes, electrical stimulation therapy according to each subset via a respective set of electrodes different from sets of electrodes of each other subset of the therapy parameter sets. The medical device iteratively delivers the electrical stimulation therapy according to the subsets of the therapy parameter sets via the respective sets of electrodes. Further, the medical device selects at least one subset of the therapy parameter sets that treat a condition of the patient for defining subsequent delivery of electrical stimulation to the patient. |
| US10987514B2 |
System and method for minimally invasive lead implantation for cavernosal nerve stimulation controlled and powered wirelessly from an external source
Provided is a system and method for cavernosal neuromodulation as directed by a wireless remote controller and power supply. The system including: an implantable lead having at least one electrode structured and arranged to be disposed proximate to the cavernous nerve in a penis; a portable power supply; and a controller having wireless communication electronics and control circuitry associated with the wireless communication electronics structured and arranged to wirelessly couple the power supply to the at least one electrode, the controller further structured and arranged to permit a user to select at least one instruction set for the at least electrode. The controller and power supply may be provided by a control ring. An associated method of use is also provided. |
| US10987510B2 |
Systems and methods for automated muscle stimulation
A method of electrically stimulating a target muscle of a patient includes placing at least one stimulation electrode in electrical contact with the target muscle and applying an electrical signal to the stimulation electrode. The method further includes obtaining a signal from a sensing element placed on the patient, wherein the sensing element is configured to detect at least one biological parameter of the patient associated with contraction of the target muscle caused by the application of the electrical signal, and adapting stimulation of the target muscle by the at least one stimulation electrode using the obtained signal. |
| US10987509B2 |
Systems including neuromuscular stimulation cuff
The present disclosure describes systems, methods, devices for performing thought-controlled neuromuscular stimulation. Also described are methods for producing a neuromuscular stimulation cuff. The systems and methods generally relate to receiving and processing thought signals indicative of an intended action, and then delivering stimulation to effectuate the intended action through a neuromuscular stimulation cuff. The neuromuscular stimulation cuff includes a flexible printed circuit board having at least one finger and a plurality of electrogel discs disposed on the at least one finger. The neuromuscular stimulation cuff may be produced by providing a layer of polyimide, etching a conductive copper circuit including a plurality of electrodes into the layer of polyimide to form an etched circuit layer, adhering a cover layer onto the etched circuit layer to form a flexible printed circuit board (PCB), and cutting at least one finger from the flexible PCB. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement. |
| US10987506B2 |
System and method for omni-directional bipolar stimulation of nerve tissue of a patient via a surgical tool
A surgical tool including first connecting elements, contacting elements, and conductive elements. The contacting elements are configured to contact nerve tissue of a patient. The conductive elements extend from the connecting elements to the contacting elements. The conductive elements have respective insulative outer layers. The insulative outer layers isolate the conductive elements from each other. The first connecting elements are configured to connect to and receive monophasic stimulation pulses from second connecting elements on a modular stimulation module. The modular stimulation module is configured to connect to the tool and other tools via the second connecting elements. The conductive elements are configured to transfer the monophasic stimulation pulses from the connecting elements to the contacting elements. |
| US10987505B2 |
Infusion pump assembly
A fluid connector assembly is disclosed. The fluid connector assembly includes a body portion, a plug portion located on the body portion, the plug portion comprising a fluid path, a tubing, a first end of the tubing fluidly connected to the plug fluid path, a catch feature located on a first end of the body portion and configured to interact with a reservoir, and a latching feature located on a second end of the body portion, the latching feature configured to interact and lock onto the reservoir. |
| US10987499B2 |
Swallowable drug delivery device and method of delivery
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. |
| US10987498B2 |
Anal and perianal therapeutic substance delivery device
A device is provided for delivery of a therapeutic agent to the anal and perianal regions. The device includes a deployable internal anchor adapted to comfortably anchor the device in the anal canal, a shaft adapted to store and release the agent to the anal canal, and an external bumper adapted to store and release the agent to the perianal tissue and externally anchor the device. |
| US10987491B2 |
Robotic catheter system
A robotic catheter system includes a cassette including a housing, a first pair of engagement surfaces, and a second pair of engagement surfaces. The housing includes a front end, a rear end, a sidewall, a first channel, and a second channel. The first pair of engagement surfaces are arranged to contact a guide wire with sufficient pressure such that when the engagement surfaces are driven, axial movement is imparted to the guide wire. The guide wire extends along the first channel, through the rear end of the housing, and through the front end of the housing. The second pair of engagement surfaces are arranged to contact a catheter with sufficient pressure such that when the engagement surfaces are driven, axial movement is imparted to the catheter. The catheter device extends along the second channel, the second channel arranged at an angle with respect to the first channel. |
| US10987485B2 |
Insertion device with safety lock
The invention relates to an insertion device (110) for inserting an analyte sensor (114) into a body tissue. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The drive mechanism (124) comprises a rotor (142) adapted to transform an actuation motion of the actuator (132) into a motion of the insertion needle holder (120) in the longitudinal direction (126). The insertion device (110) further comprises at least one safety lock (164). The safety lock (164), in a locked position, is adapted to at least partially block a rotation of the rotor (142). In an unlocked position, the safety lock (164) is adapted to permit the rotation of the rotor (142). |
| US10987482B1 |
Patient valve for use with manual resuscitator
A manual resuscitator apparatus having a patient valve includes a housing having a first port for connection to ventilator bag, a second port for connection to a patient mask and a third port for an atmospheric vent. An air channel is configured integrally within the interior of the housing and a manometer is used for receiving air from the air channel. Either a linear or dial manometer is formed as a portion of the housing so the clinician can read both patient inhalation pressure from the first port and patient exhalation pressure from the second port. |
| US10987481B2 |
Sleep apnea nasal pillows device
An interface pillow for insertion into a nostril of a user for delivering positive air pressure (e.g. during sleep) has a pliable member having a body. The body has an insertion end and a distal sealing end that includes a seal for interfacing with a cannula. An insertion bulge extends from the body limiting an insertion distance into the user's nostrils. An insertion area of the body extends between the insertion end and the insertion bulge, the sides of which angle inwardly towards the insertion end at an angle. The outer shape of the insertion area is flattened on one side for interfacing with a septum of a nose, and an upper interface area of the outer shape of the insertion area is narrower than a lower interface area of the outer shape of the insertion area to conform to a shape of a nostril of the nose. |
| US10987476B2 |
Anesthesia gas delivery and monitoring system
Various implementations include a gas delivery and monitoring apparatus that can be used, for example, to deliver oxygen and monitor exhaled carbon dioxide in a subject while under anesthesia. One advantage of the disclosed apparatus is the ability to deliver oxygen directly to the back of the mouth instead of in front of the face. Another advantage of the disclosed apparatus over existing nasal cannulas is the ability to capture carbon dioxide exhaled from both the nose and mouth. |
| US10987475B2 |
Systems for feedback control of anesthetic agent concentration
Methods and systems are provided for delivering anesthetic agent to a patient. In one embodiment, a system includes an anesthetic agent reservoir, a pump fluidically coupled to the agent reservoir, an injector configured to receive pressurized anesthetic agent from the pump, a vaporizer comprising a heated chamber configured to receive and vaporize the anesthetic agent injected by the injector and supply a mix of the vaporized anesthetic agent and medical gas to a subject via a supply line, and a controller. The controller stores instructions executable to determine a concentration of the vaporized anesthetic agent in the mix and adjust one or more injector parameters based on a difference between the concentration of the vaporized anesthetic agent and a commanded concentration. |
| US10987473B2 |
Lubricated pen needle
A pen needle (531) includes a hub (511) and a needle (513) fixedly connected to the hub (511). An outer cover (501) receives the hub (511). A lubricant reservoir (503) is disposed in the outer cover (501) such that a portion of the needle (513) is disposed in the lubricant reservoir (503) when the hub (511) is received by the outer cover (501). Lubrication of the needle (513) facilitates multiple injections. |
| US10987469B2 |
Rotatable finger loop for syringe, syringe configured to receive the rotatable finger loop and associated methods
Finger control handles for conventional syringes are disclosed. The finger control handles may be configured to be assembled with a hand-held syringe, to be secured in place on a proximal portion of the barrel of the syringe and, when secured in place, to rotate freely about a circumference of the proximal portion of the barrel of the syringe. Systems that include the finger control handles and a hand-held syringe that is configured to capture the finger control handles are also disclosed, as are various methods of use, including methods for assembling the finger control handles with the syringe and methods for connecting the syringe to an elongated medical instrument, such as a catheter. |
| US10987465B2 |
Vibrational injection apparatus
A vibrational injection apparatus suitable for use in a system for removal, delivery and/or transplantation of body tissues and other substances in medical procedures may include an apparatus housing. A vibration mechanism may be provided in the apparatus housing. A material injector may be provided in the apparatus housing and mechanically coupled to the vibration mechanism. An injection cannula may be disposed in fluid communication with the material injector. |
| US10987463B2 |
Handpiece for cleaning wounds
A handpiece for cleansing wounds with a fluid jet includes a main body, which has a front end with an emergence opening for the emergence of the fluid jet, wherein a porous body is present on the front end, which porous body surrounds the emergence opening and protrudes beyond the latter in the direction of the fluid jet outlet and forms a space through which the fluid jet can pass unimpeded. The handpiece according to the invention combines the advantages of cleansing by a fluid jet with the advantages of mechanical cleansing and, at the same time, provides effective protection against aerosols. |
| US10987460B2 |
Methods and systems of generating rapidly varying pressure amplitudes in fluidic circuits in a dialysis treatment system
The present specification describes a modular, portable hemofiltration system, for providing improved clearance levels of blood toxins, which includes at least one roller pump that is designed and operated to generate a rapidly varying pressure profile of fluid within at least a blood circuit of the hemofiltration system. |
| US10987459B2 |
Method and system for the calibration of devices for identifying blood or blood constituents in a fluid
The invention relates to a method and to an assembly for calibrating devices 11 for detecting blood or blood components in a liquid, in particular dialysate, which devices comprise a light transmitter 17 and a light receiver 18, and an evaluation unit 20 that receives the signal from the light receiver 18 and is designed such that blood or blood components in the liquid are detected on the basis of the weakening of radiation passing through the liquid. The method according to the invention is based on the fact that the calibration of the devices 11 for detecting blood or blood components is carried out without the use of blood. The calibration is carried out using an absorption standard 30, which has predetermined optical properties in relation to the absorption of the light in blood, the absorption standard 30 being arranged in the beam path 19 between the light transmitter 17 and the light receiver 18. The absorption standard 30 makes it possible to identify defined spectral weakening in the light depending on the components of the blood, in particular haemoglobin. Since, by contrast with blood, the absorption standard 30 does not bring about any scattering, meaning that the beam path is influenced in a different way from blood, the calibration is also carried out using a scattering standard 36, which has predetermined optical properties in relation to the scattering of the light in blood. The assembly also comprises a beam deflection unit 22 for coupling out light for a spectral measurement of the light transmitter 17 using a spectrometer 27. |
| US10987456B2 |
Devices for use in extracting percutaneous ventricular assist devices
A system and method for extracting a pVAD device that is implanted with a distal portion in an aorta of the heart and a drive line extending across an inter-atrial septum and out of the body via a superior vessel of the venous vasculature, include a first device that is introduced into a femoral artery and through the descending aorta used to engage a distal part of the pVAD device in the aorta of a patient using an instrument. A second, cutter, device is introduced into the venous vasculature superior to heart, advanced to a position adjacent the inter-atrial septum, and used to cut the pVAD drive line adjacent to the inter-atrial septum. After cutting, a first portion of the pVAD is withdrawn from the body via the venous vasculature, and a second portion is withdrawn from the body via the femoral artery. |
| US10987454B2 |
Reduced-pressure wound treatment systems and methods employing manifold structures
Manifold structures, systems, and methods are disclosed that include using longitudinal members and one or more shaped projections to cause microstrain at a tissue site. In one instance a manifold structure includes a plurality of spaced longitudinal members and at least one shaped projection coupled to at least one of the plurality of longitudinal members for creating a microstrain at a tissue site. The at least one shaped projection includes a columnar member having a distal end and includes an enlarged member positioned at the distal end of the columnar member. The columnar member has a first outer diameter (D1) and the enlarged member has a second outer diameter (D2). The second outer diameter of the enlarged member is greater than the first outer diameter of the columnar member (D2>D1). Other systems, methods, and structures are presented. |
| US10987447B2 |
Antibacterial dressing material and preparing method therefor
The present invention relates to an antibacterial dressing and a method for preparing the same. According to the present invention, there are provided an antibacterial dressing containing a rapid cell membrane-penetrating component that exhibits excellent bactericidal and antibacterial activities by disrupting the structure and synthesis of protein and nucleic acid, and a method for preparing the same. |
| US10987444B2 |
Integrated fogging system providing atomized solution to an enclosed treatment area and related methods
A system for disinfecting an enclosed area having an access door with an atomized disinfectant fluid may include a fogging device including a housing and an atomizing disinfectant generator carried by the housing including an atomizing nozzle in fluid communication with a disinfectant fluid reservoir, and a compressor coupled to the atomizing nozzle. The fogging device may further include a processor, and the system may further include a controller configured to selectively actuate an electronic door lock actuator to lock and unlock the access door. The processor may be configured to communicate with the controller to initiate an automated disinfection treatment cycle during which the compressor dispenses atomized disinfectant fluid into the enclosed area via the atomizing nozzle while the access door is locked, and to not dispense atomized disinfectant fluid into the enclosed area while the access door is unlocked. |
| US10987440B1 |
Ultraviolet pathogen disinfection system
A pathogen disinfection system includes a base and a pathogen disinfection apparatus having a UV light source disposed in the base and configured to emit UV light to at least partially inactivate pathogens exposed to the emitted UV light. Further, the system includes a beam shaping mechanism configured to shape a path of the emitted UV light so that the UV light is confined to a selected width, a first motion sensor configured to detect when an object or human being has moved into the UV light path and send a first signal in response to detecting such a movement, a proximity sensor configured to detect when a human being is present and send a second signal in response to detecting such a presence, and a controller to activate the UV light source after receiving the first signal and deactivating the UV light source after receiving the second signal. |
| US10987432B2 |
Therapeutic delivery and expression system, methods and uses thereof
Therapeutic methods for cancer treatments using a combined prokaryotic-eukaryotic delivery and expression system for the delivery of multiple therapeutic factors via a modified tumor-targeted bacteria. A targeted bacteria-vector system elicits an inter-kingdom dual expression (IKDE) of antitumor agents, in the nucleus or cytoplasm of eukaryotic cells, with priming and maintenance of the vector in the bacterium. The therapeutic factors include small interfering RNAs, tumoricidal proteins, DNA molecules, or a combination thereof. The system provides direct killing of tumor cells and alters the tumor microenvironment by expressing anti-angiogenic factors and cytokines in intracellular and/or extracellular environments. Also provided are methods of using natural exosomes comprising cargoes obtained from the bacterially infected cells. The bacteria-vector system is useful for many types of tumor and cancer as well as recombinant vaccines. The method causes significant regression of tumor and prolongs survival of tumor-bearing mice and subject without detectable systemic toxicity. |
| US10987429B2 |
Inhibitor of ATP-dependent cellular reverse transporters and method for producing same
A group of chiral conjugates (optically active hybrid molecules) of oligoetherpolyol structure are inhibitors of ATP-dependent reverse transporters of cells (OEP inhibitors). An OEP inhibitor is a conjugate having an equimolar ratio of optically active polyoxypropylene hexol and polyoxypropylene glycol. The produced preparation increases the efficacy of medicines by inhibiting multi-drug resistance mechanisms of cells. It may be used in biology, pharmacology, pharmaceutics, medicine, and agriculture. The inhibitor is produced by hydroxypropylation of a mixture of sorbitol and a bifunctional oxygen-containing compound in the presence of a hydroxide of an alkaline or alkaline earth metal. The bifunctional oxygen-containing compound used may be water, propylene glycol, dipropylene glycol, tripropylene glycol, tetrapropylene glycol, pentapropylene glycol, hexapropylene glycol, heptapropylene glycol or a mixture thereof. The inhibitor is a conjugate of polyoxypropylene glycol and polyoxypropylene hexol in an equimolar ratio, with a hydroxyl value within a range of 215-240 mg KOH/g. |
| US10987426B2 |
Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid
Physically stable compositions in the form of an injectable aqueous solution, wherein the pH is from 6.0 to 8.0, includes at least: a) human glucagon and b) a co-polyamino acid bearing carboxylate charges and hydrophobic radicals Hy. In one embodiment, the compositions further comprise a gut hormone. |
| US10987414B2 |
Adhesin tip multiepitope fusion antigen platform and vaccines and their use in the treatment of enterotoxigenic diarrhea
The application provides for MEFA constructs and vaccines against Enterotoxigenic Escherichia coli (ETEC). Methods for reducing the incidence of diarrhea associated with ETEC are also provided. The representative adhesin tip MEFAs and the representative major subunit CFA MEFA-II provided in the disclosure has an adhesin tip backbone or major subunit CFA with one or more adhesin tips, adhesin subunit or major structural subunit epitopes incorporated onto the backbone. The adhesin tip MEFAs and the CFA MEFA-II provided advantageously prevents the ETEC molecule from attaching to the intestine. |
| US10987413B2 |
MHC-independent tumor-associated antigens
The present invention relates to novel tumor-associated antigens, which elicit independently from a presentation via MHC a CD8-positive T-cell response. GM-CSF-Receptor alpha chain (CSF2RA) and Tyrosinase-related protein 2 (TRP-2) were found to be targets of CD8-positive T-cell clones which could detect the proteins on the surface of HLA I negative melanoma cells. Thus, the invention provides proteins, protein fragments and polypeptides of the novel antigens for use in medicine, for example for the treatment, diagnosis and prevention of a tumor disease. Furthermore provided are nucleic acids expressing the antigens of the invention, binding agents specific for the antigens of the invention, such as T-cell receptor chains and isolated T cells which are reactive against the antigens of the invention or which express the T-cell receptors of the invention. The invention further pertains to pharmaceutical compositions, especially vaccine compositions, comprising the antigens, nucleic acids, binding agents or T cells in accordance with the invention, and methods for the generation of T cells, which are specifically reactive to the antigens of the invention in an MHC-independent manner. |
| US10987408B2 |
Compositions and methods for modulating toll-like receptor 2 activation
A method of promoting hair growth of a subject includes administering to follicle cells of the subject a therapeutically effective amount of a TLR2 agonist that promotes TLR2 activation and hair growth of the subject. |
| US10987403B2 |
Cyclodextrin-Nle3-A(1-7) compositions and their use
Disclosed herein are compositions including cyclodextrin and Nle3-A(1-7) [Asp-Arg-Me-Tyr-Ile-His-Pro (SEQ ID NO: 1)] and their use in treating various disorders. |
| US10987401B2 |
Adiponectin peptidomimetics for treating ocular disorders
Provided herein are compositions and methods for treating dry eye or an ocular disease associated with inflammation in a subject in need thereof. The therapeutic compositions comprise an adiponectin peptidomimetic compound, and a pharmaceutically acceptable carrier. Also provided are methods for alleviating one or more symptoms or clinical signs of dry eye or an ocular disease associated with inflammation in a subject in need thereof. |
| US10987400B2 |
Methods for the treatment of glaucoma and age-related macular degeneration by a peptide D-TRP-AIB
Methods for the prevention and treatment of ocular disorders, in particular glaucoma, through blocking the toxic effects of β-amyloid (Aβ) derivatives, and pharmaceutical compositions for effecting such prevention and treatment thereof. |
| US10987395B2 |
Paliurus ramosissimus (Lour.) Poir. extract and preparation methods and uses thereof
The invention belongs to the field of medicine, involving new uses of Paliurus ramosissimus (Lour.) Poir. and its extract, in particular the use of Paliurus ramosissimus (Lour.) Poir. and its extract in preparation of drugs with anti-fibrotic, anti-fungal, and anti-tumor activities, for the treatment of oral and digestive tract inflammation or (and) ulcer-related diseases, or with bi-directional immunomodulatory effects. |
| US10987394B2 |
Method for preparing an extract of Chrysanthemum morifolium with an effect of treating skin diseases, extract of Chrysanthemum morifolium with an effect of treating skin diseases and pharmaceutical composition containing the extract
The present disclosure provides a method for preparing an extract of Chrysanthemum morifolium with an effect of treating skin diseases, including: (a) performing an extraction procedure on Chrysanthemum morifolium with an extraction solvent to obtain an extract solution; and (b) adding at least one glycoside hydrolases to the extract solution to make an enzyme reaction occur to produce a precipitate, wherein the precipitate is the extract of Chrysanthemum morifolium with an effect of treating skin diseases. |
| US10987392B2 |
Method for preventing and controlling viral infections in salmonid fish using Quillaja saponaria extracts
The present invention provides a new method for preventing and controlling viral diseases in salmonid fish using Quillaja extracts, wherein said method comprises administering to salmonid fish an effective amount of a medicinal composition comprising a Quillaja saponaria extract as active ingredient. |
| US10987385B2 |
Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon; and methods for making and using them. In alternative embodiments, compositions and methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated travelers diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection. In alternative embodiments, the invention provides pharmaceuticals and products (articles) of manufacture for delivering these compositions and formulations to an individual, e.g., a human or an animal. The invention also provides devices for delivering a fecal material to a patient. |
| US10987373B2 |
DNA origami nanostructures for treatment of acute kidney injury
Disclosed herein are methods of treating acute kidney injury. The A method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M1 3 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs. |
| US10987372B2 |
Anti-hepatoma-virus agent
It is an object of the present invention to provide a novel therapeutic agent for hepatoma viruses. Specifically, the present invention relates to an anti-hepatoma virus agent, containing as an active ingredient a compound represented by the following Formula (I) or a pharmaceutically acceptable salt thereof: (wherein R1 is fluorine or hydrogen). |
| US10987371B2 |
Methods of preventing or treating filovirus and flavivirus diseases
A method of reducing the risk of filovirus hemorrhagic fever or a symptom thereof in a mammal host exposed to a filovirus (e.g., Ebola or Zika virus), comprising administering an effective amount of quercetin-3 β-O-D-glucoside (Q3G) or an analogue thereof, or a composition comprising Q3G or analogue thereof and a pharmaceutically acceptable carrier, to said host prior to said exposure. |
| US10987365B2 |
Compositions and methods for the treatment of pain
The claimed invention relates to compositions that may be in a form of a liquid, solid, gel, cream or gel capsule comprising an analgesic, and methods for administering these compositions for treatment of patients suffering from various forms of pain. |
| US10987361B2 |
Treating auto-immune and auto-inflammatory diseases
The present invention relates to the formulations, methods and kits for reducing cytokine interleukin-17 (IL-17 or IL-17A) levels in both broncheoalveolar lavage fluid (BALF) and blood/serum and/or for the inhibition of p38 mitogen activating protein kinase (MAPK) activity involving the use of 17α-hydroxyprogesterone caproate (17-OHPC) or derivatives thereof. The formulation may be in the form of an inhalant containing effective amounts of 17-OHPC, and the formulation may be used in a method to treat IL-17 cytokine and/or p38 MAPK mediated auto-immune and auto-inflammatory diseases. Such diseases may include glucocorticoid (GC) insensitive related diseases or conditions. In alternate embodiment, the formulation may include the combined use of budesonide (BUD) with 17-OPHC. |
| US10987360B2 |
Hepatitis B core protein modulators
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula: |
| US10987357B2 |
Aerosolized fluoroquinolones and uses thereof
Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described. |
| US10987354B2 |
Inhibitors of influenza virus replication and uses thereof
The invention provides a class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza. |
| US10987352B2 |
Ophthalmic formulations of cetirizine and methods of use
The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye. |
| US10987350B2 |
Method for treating post-traumatic stress disorder
Disclosed and described is a novel dose titration procedure for administering the opioid antagonist, nalmefene, to a patient diagnosed with post-traumatic stress disorder (PTSD). |
| US10987349B2 |
Antitumor agent and bromodomain inhibitor
It is an object of the present invention to provide an antitumor agent, which is further excellent as a treatment agent used in the prevention and/or therapy of tumor associated with a bromodomain, and also to provide a bromodomain inhibitor, which is useful as a treatment agent for diseases or states associated with a bromodomain.An antitumor agent and a bromodomain inhibitor, comprising a compound represented by the following formula, have an excellent bromodomain inhibitory activity and are useful as treatment agents in the prevention and/or therapy of tumor associated with a bromodomain, and the like: wherein R1 represents a C1-6 alkyl group, etc.; R2 represents a hydrogen atom, etc.; R3 represents a halogen atom, etc.; Z1, Z2 and Z3 each represent CH, etc.; X1 represents CONH, etc.; Ring A represents a phenyl group, etc.; R4 represents a halogen atom, etc.; and m represents an integer from 0 to 5. |
| US10987348B2 |
Modulators of ATP-binding cassette transporters
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention. |
| US10987340B2 |
Composition and method for rapidly inducing an endogenous ketosis
A composition and method for rapidly inducing a state of endogenous ketosis, the composition including: about 26.66-28.57 percent by mass of alpha lipoic acid; about 0.01-0.02 percent by mass of chromium picolinate; about 47.61-49.99 percent by mass of L-arginine; and, about 23.33-23.81 percent by mass of calcium carbonate. The method includes restricting carbohydrate consumption to a maximum dosage of about 20 grams prior to consumption of the composition and wherein consumption of the composition is on an empty stomach. About thirty minutes after consumption of the composition the user performs moderate intensity exercise. About three hours after consuming a first dose the user tests for a presence of ketones in urine utilizing at least one sodium nitroprusside urine ketone reagent strip. |
| US10987339B2 |
Uses of butylidenephthalide
A method for decreasing the incidence rate and/or recurrent rate of cancer is provided. The method comprises administering to a subject in need an effective amount of butylidenephthalide (BP). |
| US10987338B2 |
Composition containing artesunate
The present disclosure provides a composition of artesunate, a process of preparing the same, and a method of treatment. |
| US10987335B2 |
Pharmaceutical composition for oral administration comprising high concentration taxane
The present invention provides a pharmaceutical composition for oral administration, consisting essentially of (a) 4 to 40% by weight of a taxane, (b) 10 to 40% by weight of polyoxyl glyceryl fatty acid ester, (c) 30 to 70% by weight of monooleoyl glycerol or 30 to 70% by weight of an oleoyl glycerol complex having 30 to 65% by weight of monooleoyl glycerol contents; 15 to 50% by weight of dioleoyl glycerol contents; and 2 to 20% by weight of trioleoyl glycerol contents, and (d) 5 to 30% by weight of a surfactant and a process for preparing the same. |
| US10987331B2 |
Methods of treating mixed dyslipidemia
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate. |
| US10987326B2 |
Butyrate and beta-hydroxybutyrate compositions
Compositions and methods for providing a person with an exogenous and therapeutically effective supply of ketones are disclosed. The compositions may consist essentially of (a) purified butyrate (or esters or propionate salts thereof) and (b) purified beta-hydroxybutyrate (or esters or propionate salts thereof). The compositions may further include other pharmacologically active agents, such as acetyl-L carnitine, R-alpha lipoic acid, green tea extract, vitamins, and various combinations of such agents. The methods include providing a person with an exogenous supply of ketones, by orally administering a pharmacologic composition, which is effective to deliver 2000-5000 mg of a short chain fatty acid (e.g., butyrate) and 5000-10,000 mg of ketone (e.g., beta-hydroxybutyrate) on a daily basis. |
| US10987322B2 |
Immunoregulatory agents
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided. |
| US10987320B2 |
Methods and compositions for preventing or treating calciphylaxis
The invention provides methods and compositions for preventing or treating (e.g., slowing the progression of, arresting, and/or reversing) calciphylaxis in a subject in need thereof and, more particularly, the invention relates to methods of using menaquinone-7 (MK-7) and/or menaquinol-7 (MKH2-7) for preventing or treating calciphylaxis in a subject with one or more of the following: diabetes, chronic kidney disease, end stage renal failure, and COPD or a subject undergoing hemodialysis and/or receiving anticoagulant therapy and/or statin therapy. |
| US10987318B2 |
Application of clofoctol for manufacturing pharmaceutical product for treating human neuroglioma
The present invention discloses an application of clofoctol for manufacturing a pharmaceutical product for treating human neuroglioma. The clofoctol is a pharmaceutical product for treating an upper respiratory tract infection. The clofoctol exerts a significant and specific inhibition of a glioma stem cell activity relative to a human neuroglioma cell or a normal human astroglia, human embryonic kidney cell, and human neural stem cell. A glioma stem cell treated with the clofoctol exhibited significantly reduced self-renewal, tumorsphere formation, and in vivo tumor formation in a nude rat. In vivo experiments using a zebrafish glioma transplantation model and a nude rat glioma transplantation model provided in vivo verification for the therapeutic efficacy of the pharmaceutical product against glioma. The invention specifically found that a clofoctol for treating an upper respiratory tract infection can achieve targeted inhibition of the glioma stem cell, and can thus be used in preparing a pharmaceutical product for treating human neuroglioma. The invention provides a novel therapeutic pharmaceutical product for treating human neuroglioma. |
| US10987314B2 |
Antigen-specific, tolerance-inducing microparticles and uses thereof
The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes. |
| US10987312B2 |
Controlled release dosage form with enhanced pharmacokinetics
The present invention provides a simple and improved dosage form that is capable of providing a controlled release of GABAB receptor agonist contained in the core thereof. The invention also provides methods of administering the dosage form and of treating conditions that are therapeutically responsive to GABAB receptor agonist. |
| US10987311B2 |
Extended release compositions comprising pyridostigmine
Extended release pyridostigmine dosage forms, suitable for maintaining stable plasma concentrations with reduced or minimized initial burst release/dose dumping of pyridostigmine, are provided. The dosage forms include matrix tablets, gastroretentive tablets, and pellets, the latter being suitable for dosing in capsules, tablets, and sachets, as well as for sprinkling on foodstuffs. The disclosure also provides methods for improving patient compliance by administering once-a-day extended release pyridostigmine bromide dosage forms that provide a superior controlled drug release. |
| US10987310B2 |
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form. |
| US10987308B2 |
Therapeutic nanoparticles and related compositions, methods and systems
Disclosed are targeted sub-50 nanometer nanoparticles suitable for delivering bioactive agents of interest, and related compositions, methods, and systems, which improve the manufacturing, stability, efficacy and other aspects of therapeutic nanoparticles. |
| US10987298B2 |
Mascara compositions comprising a polymer having cyclic amide, cyclic amine and acrylamide functionality
A mascara composition includes a vehicle comprising water; a primary film-forming polymer that is a non-ionic and water-soluble or water dispersible copolymer comprising a first cyclic amide monomer, a cyclic amine monomer, and an acrylamide monomer; at least one nonionic secondary film-forming polymer having a fraction of a second cyclic amide monomer that is at least about 70% by weight of the at least one secondary film-forming polymer; and from about 0.5% to about 8% by weight of a C2-C5 alcohol. |