Document | Document Title |
---|---|
US10947361B2 |
Ethylene polymer, stretched molded article and microporous membrane
The present invention presents an ethylene polymer, wherein the ethylene polymer has a weight average molecular weight (Mw) of 200,000 or more and 3,000,000 or less, a proportion of a component (α130) with the lowest mobility of 40% or more and 60% or less, and a ratio β/γ of a middle motion component (β) to a component (γ) with the highest mobility of 1.0 or more and 4.0 or less when a three-component approximation of free induction decay at 130° C. measured by a solid echo method of pulse NMR is performed. |
US10947359B2 |
Bead expanded molded article, resin expanded particles, method for producing resin expanded particles, expandable resin particles and method for producing bead expanded molded article
Provided is a bead expanded molded article comprising a plurality of resin expanded particles that are fusion-bonded with each other, in which the resin expanded particles mainly include a resin having a glass transition temperature of 180° C. or more. |
US10947357B2 |
Polymeric material for container
A formulation for producing a polymeric material including high-density polyethylene, a chemical blowing agent, and other optional components is described. |
US10947353B2 |
Resin composition
A resin composition for insulating coating material, comprises: a polyimide resin and/or a precursor thereof; and a polymer having a heterocyclic ring at a side chain, wherein the content of the polymer having a heterocyclic ring at a side chain is 0.1 to 7 parts by weight relative to 100 parts by weight of the polyimide resin and/or the precursor thereof. By adding a prescribed amount of the polymer having a heterocyclic ring at a side chain, there can be obtained a resin composition for insulating coating material still maintaining heat resistance and together having excellent bending resistance. |
US10947352B2 |
Structure material and manufacturing method therefor
Provided is a mountain-shaped structure material being excellent in stiffness and lightness. The present invention is a structure material including a resin, reinforced fibers and voids. The structure material has a specific bending stiffness represented as Ec1/3·ρ−1 being 2.5 or more where a bending modulus is Ec and a density is ρ. The structure material has a mountain shape. |
US10947350B2 |
Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same
Provided are multiply functional charged telodendrimers. The telodendrimers can be used for protein encapsulation and delivery. The charged telodendrimers may have one or more crosslinking groups (e.g., boronic acid/catechol reversible crosslinking groups). The telodendrimers can aggregate to form nanoparticles. Cargo such as combinations of proteins and other materials may be sequestered in the core of the nanoparticles via non-covalent or covalent interactions with the telodendrimers. Such nanoparticles may be used in protein delivery applications. |
US10947346B2 |
Polyarylene sulfide resin, method for producing same, poly(arylene sulfonium salt), and method for producing poly(arylene sulfonium salt)
Disclosed is a production method comprising a step of obtaining a poly(arylene sulfonium salt) comprising a terminal group including at least one functional group selected from the group consisting of a carboxy group, a hydroxy group and an amino group, and a step of dealkylating or dearylating the poly(arylene sulfonium salt) to obtain a polyarylene sulfide resin, and a polyarylene sulfide resin comprising a terminal group including a functional group obtainable by the production method. |
US10947339B2 |
Anion exchange resin, method for producing thereof, electrolyte membrane for fuel cell, binder for forming electrode catalyst layer, fuel cell electrode catalyst layer and fuel cell
Provided are an anion exchange resin being capable of producing an electrolyte membrane for a fuel cell, a binder for forming an electrode catalyst layer and a fuel cell electrode catalyst layer, which have an improved physical property (anion conductivity); a method for producing thereof; an electrolyte membrane for a fuel cell, a binder for forming an electrode catalyst layer and a fuel cell electrode catalyst layer produced from the anion exchange resin; and a fuel cell having the electrolyte membrane or the electrode catalyst layer.For example, the anion exchange resin is obtained by reacting a hydrophobic monomer with an aminoalkyl group-containing monomer, in which the hydrophobic monomer is composed of one aromatic ring or a plurality of aromatic rings to which two halogen atoms are bonded, and the aminoalkyl group-containing monomer is composed of one aromatic ring or a plurality of aromatic rings to which two halogen atoms are bonded and an aminoalkyl group is introduced; and by quaternizing the amino group. In the anion exchange resin, a divalent hydrophobic group formed by the residue of the hydrophobic monomer, and a divalent hydrophilic group formed by the residue of the quaternized aminoalkyl group-containing monomer are bonded via direct bond. |
US10947338B2 |
Block polymer and polymer electrolyte membrane comprising same
The present specification relates to a block polymer and a polymer electrolyte membrane including the same, a membrane-electrode assembly including the polymer electrolyte membrane, a fuel cell including the membrane-electrode assembly and a redox flow battery including the polymer electrolyte membrane. |
US10947336B2 |
Moisture curable hot melt urethane composition, method for producing cured foam of same, synthetic leather and method for producing synthetic leather
The present invention provides a moisture-curable hot melt urethane composition, including a hot melt urethane prepolymer (A) having an isocyanate group and a foaming agent composition (B) containing N,N′-dinitrosopentamethylenetetramine (b1), urea (b2) and a polyol (b3). The present invention also provides a method for producing a foamed and cured product of a moisture-curable hot melt composition, which includes heat-melting a hot melt urethane prepolymer (A), then mixing the foaming agent composition (B) therewith, applying the resultant mixture to a substrate, and performing a heating treatment at a temperature equal to or higher than heat-melting temperature of the (A) to thereby cause foaming and curing. An object of the present invention is to provide a solvent-free foaming system, according to which a foamed and cured product with excellent texture can be obtained, and an excellent foamed state can be maintained even in a thin film. |
US10947335B2 |
Triazine-precondensate-aldehyde condensation products and method for obtaining the same
The present invention relates to a triazine-precondensate-aldehyde condensation product obtainable by reacting a) at least one triazine compound of the general formulae (I), b) at least one aldehyde, and c) at least one triazine precondensate of the general formula (II). A method for obtaining a condensation product and a wood based panel are also disclosed. |
US10947334B2 |
Anionic thermoviscosifying water-soluble polymers, preparation method and application thereof
A method for preparing an anionic thermoviscosifying water-soluble polymer includes the following steps: performing an inverse emulsion polymerization by using acrylamide, acrylic acid and Pluronic triblock polymer. The high reactivity of acrylamide and the inverse emulsion polymerization can increase the molecular weight of the thermoviscosifying polymer, and exhibit an obvious thermoviscosifying effect even at a low polymer concentration, which can reduce the application cost. The dissolution rate of the obtained polymer emulsion is significantly higher than the dissolution rate of the dry powder of the polymer. The obtained emulsion-diluted solution has a relatively strong thermoviscosifying behavior after further adding a small amount of reverse demulsifier, and the emulsion-diluted solution exhibits different thermoviscosifying behaviors as the amount of the reverse demulsifier is increased. |
US10947332B1 |
Copolymer with programmable water solubility
A copolymer composition including a method having a first step involving heating and submerging of LDPE into a heptane bath until the LDPE dissolves into the heptane bath resulting in a water-like solution. A second step including precipitating of the water-like solution forming a PE wax within the water-like solution. A third step involving filtering and distilling of the water-solution separating the PE wax from the heptane bath. A fourth step involving dispersing of the PE wax in a liquid carrier resulting in a combination. A fifth step involving polymerizing of the PE wax into LDPE by introducing the combination into PVA during an extrusion process resulting in a homogeneous mixture. A sixth step involving programming the water solubility of the homogeneous mixture. Resulting in the copolymer composition having programmable water solubility, shelf-life stability and quality in the presence of moisture or liquids for a predetermined length of time. |
US10947329B2 |
Catalyst systems and processes for using the same
A catalyst system including two or more metallocene catalysts and processes for using the same to produce polyolefin polymer compositions are provided. The polyolefin polymer compositions have a good balance of a melt index ratio and normalized melt strength. |
US10947328B2 |
Polymer comprising a plurality of phenothiazine groups and methods of making the same
A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded. |
US10947326B2 |
Adhesive composition, cured article, semiconductor device, and production method for same
An adhesive composition comprising (a) a (meth)acrylic polymer, (b) a compound having at least two (meth)acryloyl groups, (c) a polymerization initiator and (d) a filler. |
US10947323B2 |
Capped cyclodextrin-hydrophobic moiety conjugate, cyclodextrin supramolecular polymer, and cyclodextrin-siRNA complex and method of synthesis thereof
The invention relates to a capped cyclodextrin-hydrophobic moiety conjugate, to a supramolecular polymer formed of capped cyclodextrin-hydrophobic moiety conjugates according to the invention and to a siRNA-cyclodextrin complex comprising a supramolecular polymer according to the invention. The invention also relates to a method for manufacturing the capped cyclodextrin-hydrophobic moiety conjugate, the supramolecular polymer, the siRNA-cyclodextrin complex according to the invention. The capped cyclodextrin-hydrophobic moiety conjugate of the invention comprises a capped cyclodextrin group and at least one hydrophobic moiety bound by a first linker to one of the carbon atoms of the cap. The invention can be used for various applications in particular in the pharmaceutical field. |
US10947316B2 |
Antibody-drug conjugates containing anti-Globo H antibodies and uses thereof
An immunoconjugate includes an anti-Globo H antibody, or a binding fragment thereof, and a therapeutic agent or a label, having the formula: Ab−(L−D)m, wherein Ab is the anti-Globo H antibody or the binding fragment thereof, L is a linker or a direct bond, D is the therapeutic agent or the label, and m is an integer from 1 to 8. The antibody may be a monoclonal antibody, which may be a humanized antibody. A method for treating a cancer includes administering to a subject in need of such treatment a pharmaceutically effective amount of an immunoconjugate containing an antibody against Globo H, or a binding fragment thereof, and a therapeutic agent covalently conjugated with the antibody. |
US10947314B2 |
Antibodies targeting b-cell maturation antigen and methods of use
The presently disclosed subject matter provides antibodies that bind to B-cell maturation antigen (BCMA) and methods of using the same. |
US10947311B2 |
VCAM-1 mediated methods and compositions for treating aging-associated impairments
Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include reducing cell surface VCAM-1 activity in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments. |
US10947309B2 |
IL-6 antibodies
Improved IL-6 antibodies are provided. Uses of the antibodies in the treatment of IL-6-related diseases, e.g., ocular diseases such as diabetic macular edema, are disclosed. |
US10947301B2 |
Method of treating extracellular tissue and vascular calcification and arteriosclerosis
A novel therapy concept based on a removal of circulating BSP (bone sialoprotein) from the plasma of patients with chronic kidney disease (CKD) or highly at risk of developing arterial and vascular calcifications. The method comprises method of treatment of extracellular tissue and vascular calcifications, atherosclerosis, arteriosclerosis, and arterial calcification. The beneficial effects of this therapy have been proven by the observed correspondence between levels of circulating free BSP levels and mortality of CKD patients as well as in animal models. |
US10947300B2 |
Agents for influenza neutralization
The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza. |
US10947298B2 |
Methods of use of secretory IgA
Described herein dog and cat food additives and compositions comprising secretory IgA. |
US10947292B2 |
Ultra-long acting insulin-Fc fusion proteins and methods of use
The present disclosure provides recombinantly manufactured ultra-long acting insulin-Fc fusion proteins for use in treating canine and feline diabetes. The insulin-Fc fusion proteins comprise an insulin polypeptide linked via a peptide linker to an Fc-fragment of canine or feline origin. Based on the results obtained, creating a treatment that is amenable to low cost manufacturing, exhibits sufficient in vivo bioactivity, displays extended duration of bioactivity, does not induce anti-drug antibodies, and substantially retains is potency over multiple administrations, requires a non-obvious combination of insulin polypeptide, peptide linkers, and species-specific Fc fragment, in addition to selective mutations on one or more of these components. Exemplary ultra-long acting insulin-Fc fusion proteins, polynucleotides encoding these insulin-Fc fusion proteins, and pharmaceutical formulations of exemplary insulin-Fc fusion proteins are provided, in addition to methods of use and preparation. |
US10947287B2 |
DNA coding sequence for human G-CSF
The present invention relates in general to a nucleic acid encoding human granulocyte-colony stimulating factor (G-CSF), wherein the first leucine residue occurring on the N-terminal end of the encoded G-CSF is encoded by a codon other than the CTG/CUG codon, and wherein the nucleic acid does neither comprise the nucleic acid sequence according to SEQ ID NO: 1, nor according to SEQ ID NO: 2, nor according to SEQ ID NO: 3, nor according to SEQ ID NO: 4. The present invention also relates to a nucleic acid 100% complementary to the aforementioned nucleic acid, as well as to vectors and host cells comprising the aforementioned nucleic acids. Finally, the present invention relates to methods for producing human G-CSF using these nucleic acids, vectors and/or host cells and resulting G-CSF compositions. |
US10947286B2 |
Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
US10947284B2 |
Fusion molecules
The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein. |
US10947283B2 |
Core domain of annexins and uses thereof in antigen delivery and vaccination
The present disclosure provides immunogenic compositions, such as vaccines, including DNA vaccines, and uses thereof, e.g., which include an annexin core domain to mediate efficient antigen delivery and antigen presentation in order to induce an antigen-specific immune response and/or to treat or prevent infectious diseases and/or cancer. |
US10947278B2 |
Recombinant vector comprising porcine FC fragment and preparation method of recombinant protein using thereof
Provided is a recombinant vector including a porcine Fc fragment. By fusing the porcine Fc fragment with various target proteins by using the recombinant vector of the present invention, not only target proteins may be expressed using various hosts including plants, but the productivity and stability of target proteins may also be increased. |
US10947277B2 |
Nucleic acids encoding zika virus-like particles and their use in zika virus vaccines and diagnostic assays
Transcriptional units encoding Zika virus (ZIKV) premembrane (prM) and envelope (E) proteins, which upon translation form Zika virus-like particles (VLPs), are described. Use of the transcriptional units and VLPs in three different ZIKV vaccine platforms is described. Immunoassay-based detection methods using ZIKV VLPs are described for the diagnosis of ZIKV infection. |
US10947272B2 |
BACE1 inhibitor peptides
The present invention relates to dual-site BACE1 inhibitors, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease. |
US10947270B2 |
Targeted prodrug cytosine deaminase fusion carrier and application thereof
The present invention provides a targeted prodrug enzyme fusion carrier comprising a targeted molecule and a prodrug enzyme. The targeted prodrug enzyme fusion carrier can effectively identify and bind to tumor cells and tumor-induced tumor angiogenesis. The targeted prodrug enzyme fusion carrier also has a targeted prodrug enzyme fusion protein and a theranostic system utilizing the method of in vivo nuclear medicine for the clinical diagnosis and treatment of individual patients with tumors. |
US10947266B2 |
Synthesis of ursolic acid nanoparticles
The synthesis of ursolic acid nanoparticles includes dissolving ursolic acid powder in methanol, boiling water for five minutes, and adding the methanol solution to the boiled water dropwise at a flow rate of 0.1-0.3 ml/min under ultrasonic conditions. After sonication for 20 minutes, the contents are stirred for about 15 minutes, and then dried. Particle size distribution studies and TEM micrographs confirm the resulting product comprises nanoparticles. In vitro testing confirms the ursolic acid nanoparticles exhibit greater anticancer activity than conventional-size particles, and that the nanoparticles exhibit antimicrobial effect against gram positive and gram negative bacteria, as well as fungi. |
US10947261B2 |
Tetravalent platinum compound-bicyclic double-bond-containing amphiphilic polymer prodrug, nano-micelle, preparation method and application thereof
A tetravalent platinum compound-bicyclic double-bond-containing amphiphilic polymer prodrug, which has the structure as shown in formula (I): when m=1, represents when m=0, represents R represents —CH3 or —CH2CH3; L1 and L2 independently represent Cl, N3, NO3, and n is from 10 to 80. A preparation method of the prodrug is also disclosed. The method includes a step of reacting an axially dihydroxy-coordinated tetravalent platinum compound with a bicyclic double-bond-containing orthoester precursor. In addition, a nano-micelle formed by the prodrug and an application thereof are further disclosed. The amphiphilic polymer prodrug and the micelle formed therefrom have pH hypersensitivity and reduction dual responsiveness. |
US10947256B2 |
Ligand compound, organic chromium compound, catalyst system for olefin oligomerizatin, and method for oligomerizing olefin using same
The present invention relates to a ligand compound, a catalyst system for olefin oligomerization and a method for oligomerizing an olefin using same. The catalyst system for olefin oligomerization according to the present invention exhibits high selectivity to 1-hexene or 1-octene while having excellent catalytic activity, thus enabling more efficient preparation of alpha-olefins. |
US10947255B2 |
Nanocomposite containing hollow silica spheres functionalized with azole silanes
A nanocomposite containing azole modified hollow silica spheres. In particular, the nanocomposite involves a silanization reaction product of an azole-functionalized silane linker and hollow silica spheres. The azole-functionalized silane linker is produced via a ring-opening reaction a silane coupling agent having an epoxide group and an azole compound. A method of making the nanocomposite is also specified. |
US10947252B2 |
Inhibitors of KEAP1-Nrf2 protein-protein interaction
Sultam compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the KEAP1-Nrf2 interaction, such as inflammatory bowel disease, including Crohn's disease and ulcerative colitis. |
US10947251B2 |
Therapeutic compounds and methods of use thereof
The invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof; wherein, A, B, ring C, R3, R4, R5, R6, and R7 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions. |
US10947248B2 |
4β-amidotriazole linked podophyllotoxin derivatives as potential anticancer agents
The present invention relates to a compound of general formula (A). The invention provides asynthesis of new 4β-amidotriazole linked podophyllotoxin derivatives of general formulae 8a-z to 9a-z useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof. Wherein n=0, 1 and R1-R5═[H, CI, F, CH3, OCH3, 3,4(-OCH2O—), CF3, OCF3, m-OC6H5, OH] |
US10947243B2 |
Heteroaryl SYK inhibitors
The invention relates to new substituted heteroaryls of formula 1 wherein A is selected from the group consisting of N and CH D is selected from the group consisting of CH, N, NH, S and O, E is selected from the group consisting of C and N, T is selected from the group consisting of C and N, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis. |
US10947242B2 |
[1,2,4]triazolo[1,5and#8208;A]pyrimidine compounds as PDE2 inhibitors
The present invention relates to novel [1,2,4]triazolo[1,5-a]pyrimidin-yl derivatives as inhibitors of phosphodiesterase 2 (PDE2). The invention is also directed to pharmaceutical compositions comprising the compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which PDE2 is involved, such as neurological and psychiatric disorders. |
US10947237B2 |
Antimicrobial compounds and methods of making and using the same
The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. |
US10947234B2 |
PRMT5 inhibitors
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts thereof, which are PRMT5 inhibitors. |
US10947228B2 |
Indazole inhibitors of the Wnt signal pathway and therapeutic uses thereof
Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. |
US10947226B2 |
Bicyclic pyridone lactams and methods of use thereof
The invention provides novel compounds having the general formula I: wherein R1, X, Z1 to Z5, L, n, the A ring, and the B ring, are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds. |
US10947224B2 |
Hepatitis B core protein allosteric modulators
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound. |
US10947217B2 |
Isoquinolin-3-YL carboxamides and preparation and use thereof
Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. |
US10947215B2 |
Heteroaryl compounds and their use as therapeutic drugs
The present invention provides heterocyclic compounds, the stereoisomer thereof, the enantiomer thereof, or the pharmaceutically acceptable salt, which are capable of modulating the activity of Mer receptor tyrosine kinase (MERTK). This invention also provides pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament.The present invention is directed to MERTK inhibitory compounds with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to MERTK dysregulation. |
US10947213B1 |
TLR7/8 antagonists and uses thereof
Compounds of Formula 1 and pharmaceutically acceptable compositions thereof are useful as TLR7/8 antagonists. |
US10947208B2 |
Organotin catalysts in esterification processes of furan-2,5-dicarboxylic acid (FDCA)
A method for preparing sugar-based mono and diesters is described. The process entails the esterification of 2,5-furan-dicarboxylic acid (FDCA) with an alcohol in the presence of low loadings of a homogeneous organotin (IV) catalyst. |
US10947203B2 |
1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor
In an aspect, the invention relates to 1,4,5-substituted 1,2,3-triazole and 1,2,4,5-substituted imidazoles having a structure represented by a formula: which are modulators the pregnane X receptor (“PXR”); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of modulating an adverse drug reaction in a mammal using the compounds and pharmaceutical compositions; methods of treatment of a disorder of uncontrolled cellular proliferation, such as a cancer, using the compounds and pharmaceutical compositions; methods of modulating pregnane X receptor activity in a mammal using the compounds and pharmaceutical compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
US10947198B2 |
Chroman-substituted, tetrahydroquinoline-substituted and thiochroman-substituted heteroarotinoids as anti-cancer agents
Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems. |
US10947197B2 |
Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [18F]DCFPyL
Methods, and related compositions, for the improved synthesis of [18F]DCFPyL are disclosed. Also provided are methods, and related compositions, for the use of [18F]DCFPyL so produced. |
US10947196B2 |
Beta adrenergic agonist and methods of using the same
The present disclosure is directed to chemical compounds and to the use of such compounds in the treatment of diseases associated with an adrenergic receptor. |
US10947193B2 |
Cationic lipid
The present invention provides a cationic lipid which is able to be used for nucleic acid delivery to the cytoplasm. A cationic lipid according to the present invention is, for example, a compound represented by formula (1) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 independently represent an alkylene group having 3 to 10 carbon atoms; R1 and R2 independently represent an alkyl group having 4 to 24 carbon atoms or an alkenyl group having 4 to 24 carbon atoms; R3 represents an alkyl group having 1 to 3 carbon atoms; and X1 represents a single bond or CO—O—. |
US10947185B2 |
Crystal form of dezocine and preparation method therefor
Disclosed is a crystal form of dezocine. The X-ray powder diffraction (XRD) pattern thereof is determined using Cu/K-α1 and has diffraction peaks at the 2θ value of 9.1±0.2 and 12.2±0.2, with the height % of these diffraction peaks greater than 20. Also disclosed are a preparation method for the crystal form, a pharmaceutical composition and use thereof. The crystal form of dezocine has good solubility, the preparation method has simple operations, good reproducibility, suitability for industrial production and the like. |
US10947181B2 |
Crystalline form of tefluthrin, process for its preparation and use thereof
Provided are the crystalline form of tefluthrin of formula (I), the crystal preparation process, the analyses of the crystal through various analytical methods and using the crystal to prepare stable agrochemical formulation. Also provided is the use of various solvents towards the crystalline form preparation conditions. |
US10947180B2 |
Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPARδ and may be useful for treating conditions mediated by the same. |
US10947179B2 |
2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, composition, and method for improving function of aortic endothelial cell
The disclosure relates to a compound, 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, for improving aortic endothelial cell function and use thereof. The compound is capable of inhibiting inflammatory response of the human aortic endothelial cells caused by a saturated fatty acid, and preventing an occurrence and progression of atherosclerosis. The compound is capable of reducing human aortic endothelial inflammation caused by a saturated fatty acid, for example, reducing the mRNA levels of interleukin-6 (IL-6), and is capable of effectively protecting the function of mitochondria in human aortic endothelium from being damaged by a saturated fatty acid, for example, increasing the expression of mitochondrial complex I. |
US10947178B2 |
Method for producing vinyl acetate
Fouling of the acetic acid saturator by recycle gas in the continuous gas phase process for manufacture of vinyl acetate is reduced by adding an N-oxyl fouling inhibitor to the saturator and/or at one or more other addition sites in the process, in amounts such that the concentration of N-oxyl compound which accumulates in the saturator bottoms is from 10 to 100 ppm. The amount of N-oxyl compound in the saturator is preferably from 10-50 ppm. The reduction in fouling is evidenced by lessening the lowering of the heat transfer coefficient of the saturator over time. |
US10947177B2 |
Compounds and methods for delivery of prostacyclin analogs
This invention pertains generally to prostacyclin formulations and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing cytoprotection, preventing atherogenesis and inducing angiogenesis. |
US10947176B2 |
Antimalarial compositions and uses thereof
Provided herein are compounds, compositions and method of using thereof to treat or prevent malaria. |
US10947172B2 |
Highly active catalyst for dehydrogenation of alkanes and method of preparation thereof
The invention discloses a novel method for preparation of highly active and selective dehydrogenation catalyst, comprising of metal oxide of group VIB elements of periodic table, and at least one metal oxide from group IA and/or group VIII, supported on alumina or silica or mixture thereof, wherein the accessibility to active sites and dispersion of metal oxides is enhanced by the addition of carbonaceous material such as coke derived from coal or petroleum coke or any other form of carbon, during catalyst preparation and its combustion thereof during calcination. |
US10947169B2 |
Deployable explosive charge structure
A deployable explosive charge structure includes a carpenter's tape capable of transitioning from an undeployed state to a deployed state in which the tape extends linearly over its length, an explosive charge connected to the carpenter's tape, a connecting structure for connecting the carpenter's tape and the explosive charge, and a two-sided adhesive tape for engaging a structure (for example, a door or wall) when the carpenter's tape is in the deployed state. |
US10947165B1 |
Foliar nutritional composition and method for using same
A foliar nutritional composition and method for using same for providing nutrients and/or for treating disease in plants. The foliar nutritional composition comprises a metal salt complexed with amino acids from hydrolyzed yeast extract. The metal salt is selected for high solubility using a salt of a metal selected from the group consisting of copper, nickel, zinc, iron, manganese, and combinations thereof. Preferred metal salt are nitrates, chlorides, and combinations thereof. In the method, an aqueous solution of this composition is sprayed on the plant foliage and absorbed by the plant. |
US10947163B2 |
Foam
A foamed body that is a porous foamed body including inorganic fibers other than asbestos, and having a compressive stress when compressed at normal temperature at a compression ratio of 80% of 0.1 MPa or less and a recovery ratio when compressed at normal temperature at a compression ratio of 80% of 50% or more. |
US10947162B2 |
Braze alloys for joining or repairing ceramic matrix composite (CMC) components
A braze alloy for joining or repairing ceramic matrix composite (CMC) components comprises a braze composition including silicon at a concentration from about 48 at. % to about 66 at. %, titanium at a concentration from about 1 at. % to about 35 at. %, and an additional element selected from aluminum, cobalt, vanadium, nickel, and chromium. The braze composition comprises a melting temperature of less than 1300° C. |
US10947161B2 |
“MXene” particulate material, production process for the same and secondary battery
A particulate material with a composition expressed by Ti2Alx(C(1-y)Ny)z (where “x” is more than 0.02, “y” is 0<“y”<1.0, and “z” is from 0.8 to 1.20), the particulate material comprising layers including gap layers providing an interlayer distance of from 0.59 nm to 0.70 nm within a crystal lattice; and/or with another composition expressed by Ti3Alx(C(1-y)Ny)z (where “x” is more than 0.02, “y” is 0<“y”<1.0, and “z” is from 1.80 to 2.60), the particulate material comprising layers including gap layers providing an interlayer distance of from 0.44 nm to 0.55 nm within a crystal lattice. |
US10947155B2 |
Recycling method of dihydrate gypsum from waste gypsum boards
Gypsum derived from waste gypsum boards is calcined and converted into gypsum granules including hemihydrate and/or anhydrous type III gypsum. The calcined gypsum granules are dropped into water to prepare a gypsum slurry. Then, dihydrate gypsum particles are crystalized in the slurry. The temperature of the gypsum granules just before being dropped into the water is 90° C. or higher. |
US10947154B2 |
Heating device comprising a glazing substrate coated on both sides
A heating device equipped with a chamber defining a cavity, includes a door or wall incorporating a multiple glazing, the glazing including at least one transparent substrate coated on each face with a stack of thin layers, namely: on a first face, turned toward the cavity, a first stack that reflects heat essentially by virtue of one or more functional layers based on indium tin oxide; and on the other face, turned toward the exterior of the device, a second stack that reflects heat essentially by virtue of one or more functional layers based on a metal chosen from gold or silver. |
US10947153B2 |
Grey colored coated article with low-E coating having absorber layer and low visible transmission
A low-emissivity (low-E) coating on a substrate (e.g., glass substrate) includes at least first and second infrared (IR) reflecting layers (e.g., silver based layers) that are spaced apart by contact layers (e.g., NiCr based layers), a layer comprising silicon nitride, and an absorber layer of or including a material such as niobium zirconium which may be oxided and/or nitrided. The absorber layer is designed to allow the coated article to realize glass side reflective (equivalent to exterior reflective in an IG window unit when the coating is on surface #2 of the IG unit) grey color. In certain example embodiments, the coated article (monolithic form and/or in IG window unit form) has a low visible transmission (e.g., from 20-45%, more preferably from 22-39%, and most preferably from 25-37%). In certain example embodiments, the coated article may be heat treated (e.g., thermally tempered and/or heat bent). |
US10947149B2 |
Halogen-doped silica for optical fiber preforms
Preparation of halogen-doped silica is described. The preparation includes doping silica with high halogen concentration and sintering halogen-doped silica to a closed-pore state. The sintering includes a high pressure sintering treatment and a low pressure sintering treatment. The high pressure sintering treatment is conducted in the presence of a high partial pressure of a gas-phase halogen doping precursor and densifies a silica soot body to a partially consolidated state. The low pressure sintering treatment is conducted in the presence of a low partial pressure of gas-phase halogen doping precursor and transforms a partially consolidated silica body to a closed-pore state. The product halogen-doped silica glass exhibits little foaming when heated to form fibers in a draw process or core canes in a redraw process. |
US10947147B2 |
Device and method for fracturing a container and container comprising such a device
Provided is an expandable device for fracturing a container for liquids, for example beverages, in particular alcoholic beverages, made of glass or a similar material, wherein the device has a first retracted position according to which the device can be accommodated at least partially in a recess at a bottom section of the container without causing fracture to the container and a second extended position according to which the device is able to cause a fracture at a bottom section of the container by impact against a solid surface such as a table, with the aim to prevent reuse or recycle of the container, for example with adulterated beverages. |
US10947145B2 |
System and method for improved anaerobic digestion
A method for improved anaerobic digestion is presented. The method includes mixing a volume of waste material with water to form a feedstock mixture. The volume of waste material includes an initial amount of biomass and the feedstock mixture includes methanogenic bacteria either naturally present in the waste material or introduced artificially. The method also includes introducing one or more promoter substances to the feedstock mixture. The one or more promoter substances are capable of modifying the methanogenic bacteria. Modifying includes stimulating novel enzyme production in the methanogenic bacteria. |
US10947144B2 |
Biorefinery method and system for isolated environments
A Biorefinery System (BIOSYS) that effectively treats all human activity-derived waste (black water, grey water, and food waste streams) using biological systems and that produces as process by-products: recovered potable water, liberated free oxygen, edible protein cake (with and without lipids), soil amendments, and machinery lube oils. Additionally, the system captures and chemically binds carbon dioxide into microbial cells and associated by-products, thus producing recovered usable returned cabin air. |
US10947140B2 |
Method for establishing a wastewater bioreactor environment
A method for establishing a wastewater bioreactor environment including the step of introducing a modified polydimethylsiloxane fiber to a bioreactor tank of a membrane-aerated bioreactor. |
US10947139B2 |
Liquid waste treatment system
A liquid waste treatment system includes: a baffle tank subsystem for particle settling; a preprocess tank subsystem downstream of the baffle tank subsystem; a process tank subsystem downstream of the preprocess tank subsystem; and a storage tank subsystem downstream of the process tank subsystem for the storage of treated liquid. A Microbial Fuel Cell (MFC) processing module may be included and may be inserted into the preprocess tank subsystem or implemented in a second process tank downstream of the process tank subsystem. A faster disinfection may occur in the process tank subsystem, and a slower disinfection may occur in the second process tank according to distinct respective kill curves. An electrochemical cell may be operated in a pulse mode in liquid waste in a pulsed mode. |
US10947138B2 |
Ozone distribution in a faucet
A faucet for dispensing a fluid includes a spout, a pull-out spray head removably coupled to the spout and including an outlet, and a valve assembly in fluid communication with the outlet. Additionally, the faucet includes a fluid treatment assembly configured to output a treatment into the fluid. |
US10947136B2 |
Water purification apparatus for dental treatment
A water purification apparatus includes a water inlet; a medicine mixing device in fluid communication with the water inlet; and a water outlet interconnected to the medicine mixing device and a dental treatment center. The medicine mixing device includes a medicine storage for storing antiseptic solution, a mixing unit interconnected to the water inlet, the water outlet, and the medicine storage, and a controller interconnected to the water inlet and the medicine storage. The controller includes a sensor and a microprocessor. The controller sends the antiseptic solution from the medicine storage to the mixing unit and controls a volume of water flowing from the water inlet to the mixing unit. The microprocessor instructs the controller to control a volume of the antiseptic solution supplied from the medicine storage to the mixing unit based on a signal sensed by the sensor. |
US10947135B2 |
Fluid purification methods, devices, and systems
A fluid purification system has cells whose purifying capability can be regenerated. Some of the cells are arranged in series to reach a high level of purification. An automatic valve network is controlled to cycle the cells in a way that levels the loads on each, thereby maximizing the service interval for replacing expired cells, enabling all of the cells to be replaced at the same time after having each contributing approximately equally to the purification load, and operated such that at any one time, at least one cell is regenerated so as to enable continuous up-time. |
US10947133B2 |
Underwater systems having co-located data center and water desalination subunits
Underwater systems for data center cooling and water desalination are provided. Aspects of the systems include a data center subunit and a desalination subunit that are co-located with each other at an underwater location, where the desalination subunit is configured to receive warm water output from the data center. Aspects of the invention also include methods for cooling a data center and desalinating water using underwater systems as described herein. |
US10947131B2 |
Synergistic iron and clay-based green environmental media for nutrient removal
A method of water treatment includes flowing water that includes nitrogen and phosphorus compounds through a sorption media composition within at least one chamber of a water treatment system. The composition comprises iron filings comprising at least 5 volume (vol) % of the composition, sand particles comprising at leak 10 vol % of the composition, and clay particles comprising at least 2 vol % of the composition. The iron filings, sand particles, and clay particles are mixed together. During the flowing, the clay particles attract the nitrogen and phosphorus compounds, which become absorbed onto a surface of the iron filings and the clay, resulting in a removal of the nitrogen and phosphorus compounds and the generation of reaction products. Nitrogen and phosphorus are then recovered from the reaction products. |
US10947130B2 |
Minimal high-efficient air floatation machine and method
A minimal high-efficient air floatation machine includes an air floatation pool body, a spiral water input pipeline, a return pump, an inflation pipeline and a dissolved gas pipeline. Upper and lower ends of the air floatation pool body are cones having a scum output pipeline and a height adjustable water output pipeline. The spiral water input pipeline has chemical addition ports (a), (b). By mixing chemicals with the sewage at high speed in the water input pipeline, a quick fully-mixed effect is achieved. The scum output pipeline is disposed at the top of the upper cone of the air floatation machine for adjusting the height adjustable water output pipeline to output scum automatically. The outlet of the return pump has the inflation pipeline and dissolved gas pipeline. The inflation pipeline enters into the inlet of the return pump to achieve automatic inflation after air is sucked into the Venturi tube. |
US10947128B2 |
Liquid purifier
A water purifier includes a filter housing defining an accommodation space therein, a water discharge module including a water purifier body including a housing defining an outer appearance and a filter provided in the housing to filter raw water introduced from the outside and a water discharge nozzle mounted on the water purifier body to supply the water passing through the filter to the outside of the water purifier body, and a tray provided below the water discharge module. The water discharge module includes an elevation unit elevatably mounted on a front surface of the water purifier body so as to be elevated with respect to the water purifier body and a rotator having one side in which the water discharge nozzle is provided, rotatably mounted on the elevation unit, and allowing the water discharge nozzle to vary in position while being rotated with respect to the elevation unit. |
US10947123B2 |
Synthetic caustic composition
An aqueous caustic composition comprising: a caustic component; an additive adapted to provide an extended buffering effect to the caustic composition when such is exposed to an acid; and water. Methods of using such compositions are also disclosed. |
US10947120B2 |
Production method of low dimensional nano-material
A production method of low dimensional nano-material comprises steps of: introducing a layered material; adding an intercalating agent into the layered material; and exfoliating the layered material by ball-milling to form the low dimensional material. Mechanochemical approaches for low dimensional nano-material like graphene quantum dots synthesis offer a promise of new reaction pathways, and greener and more efficient syntheses, making them potential approaches for low cost production. |
US10947117B2 |
Mechanically stable composite electrolyte for intermediate temperature fuel cell with improved proton conductivity and methods thereof
A method of restoring the proton conductivity of a sintered pyrophosphate membrane of intermediate temperature fuel cells (IT-FCs) by introducing phosphoric acid into the sintered SnP2O7 membrane to react with the degraded SnP2O7 species and thus restore the membrane pyrophosphate and proton conductivity. Such cells operate with low external humidification, and the active area of the cells may be fabricated up to 100 cm2 in size. |
US10947116B2 |
Method to synthesize nanoparticle supercrystals
Highly ordered arrays of 3D faceted nanoparticle supercrystals are formed by self-assembly with controlled nanoparticle packing and unique facet dependent optical property by using a binary solvent diffusion method. The binary diffusion results in supercrystals whose size and quality are determined by initial nanoparticle concentration and diffusion speed. The supercrystal solids display unique facet-dependent surface plasmonic and surface-enhanced Raman characteristics. The supercrystals have potential applications in areas such as optics, electronics, and sensor platforms. |
US10947115B2 |
Process for separation of hydrogen and oxygen
Embodiments of the invention are directed to methods, processes, and systems for safely and reliably purifying hydrogen from a gas mixture containing hydrogen and oxygen. |
US10947112B2 |
Method of manufacturing semiconductor quantum dot and semiconductor quantum dot
There is provided a method of manufacturing a semiconductor quantum dot including the following steps (A1) and (B1): a step (A1) of causing a nanoparticle including a specific compound semiconductor and a salt of a specific metal a1 to react with each other to introduce the metal a1 into a surface layer of the nanoparticle; and a step (B1) of causing the nanoparticle in which the metal a1 is introduced into the surface layer and a salt of a specific metal b1 to react with each other to introduce the metal b1 into the surface layer of the nanoparticle. There is provided a semiconductor quantum dot having a structure in which a specific metal a1 and/or a specific metal b1 is introduced into a surface layer of a nanoparticle including a specific compound semiconductor. |
US10947106B2 |
Systems and methods of custom condiment dispensing
Systems and methods of custom condiment dispensing include a reservoir of base condiment and a plurality of flavoring reservoirs. A first pump is pneumatically connected to the reservoir of base condiment. The second pump is pneumatically connected to at least one flavoring reservoir of the plurality of flavoring reservoirs. A nozzle is fluidly connected to the reservoir of base condiment and fluidly connected to the plurality of flavoring reservoirs. The nozzle is configured to simultaneously dispense the base condiment and at least one flavoring therethrough. A controller receives the user selections of the base condiment and the at least one flavoring and operates the first pump and the second pump to dispense base condiment and at least one flavoring. |
US10947105B2 |
Hand held, volumetric multi material dispenser
A fluid dispenser which enables one or two liquid mixture components to be selectively or simultaneously dispensed via a manually operable selection and actuation means. The said dispenser incorporates a body, one or more fluid storage and delivery channels, a selection and actuation disc operable to cause the release of a quantity of a stored fluid, as well as articulation and clamping means which support the said disc. One or more of the said fluid channels may be urged by said disc via cams to eject a fluid or fluids from corresponding cartridges. The present device provides a scale and pointer system which permits selection of a particular volume of a fluid for ejection in a first mode of operation, or selection of a specified mutual proportion of two fluids for ejection in a second mode of operation. |
US10947101B2 |
Beverage supply apparatus
A beverage supply apparatus includes cooling device 6, milk tank 5 in storage chamber 6a of cooling device 6, and detection device 7 that detects the milk. Detection device 7 has first light guide body 7c to penetrate partition wall 12 having a multilayer box body that partitions storage chamber 6a, second light guide body 7d to penetrate partition wall 12 which faces first light guide body 7c, light projection unit 7a attached to partition-wall outer-surface-side end of first light guide body 7c to project light via the body 7c, and light receiving unit 7b attached to the partition-wall outer-surface-side end of second light guide body 7d to receive light transmitted through milk tank 5 via second light guide body 7d. The detection device detects the presence or absence of or the remaining amount of milk based on a light reception state in the light receiving unit 7b. |
US10947100B2 |
Keg closure with element for locking the valve in an open position
A closure (1) for a beverage keg (90) is provided, comprising a valve housing (20) and a valve element (30), which is movable with respect to the valve housing (20) inwardly into an open state and outwardly into a closed state. A locking system comprises a locking element (50) that is movable with respect to the valve housing (20) and is capable of holding the valve element (30) in the open state. The locking element (50) comprises a body portion (51) located inside the valve housing (20) and a leg (56) that extends outwardly from the body portion (51) to the exterior of the valve housing (20). The leg (56) comprises an engagement element (57) that is configured to engage a stop formation fixed with respect to the valve housing (20) in order to limit the maximum extent of movement of the locking element (50) in an upward direction relative to the valve housing (20) after beverage has been dispensed from the keg (90). |
US10947096B2 |
Multi-armed lifting accessory
A Multi-Armed Lifting Accessory is disclosed herein which is compact and transportable in various deployments. The Multi-Armed Lifting Accessory is advantageous and useful as it has hingedly connected loading and support arms attached to a main lifter body. The supporting arms are spring loaded allowing the Multi-Armed Lifting Accessory to stably engage with irregular shaped objects such as barge lid or a skid steer loader and allows for flexible engagement and balanced lifting operations. |
US10947090B2 |
Automatic locking mechanism and clamping devices with automatic locking mechanism
An automatic locking mechanism can include one or more annular elements having teeth facing each other or facing away from each other. The automatic locking mechanism can include a rod disposed between the annular elements. The rod can have one or more pins configured to interface with the teeth of the annular elements. The pins and the teeth are also configured to rotate the rod when the annular elements move relative to the rod. The rotation of the rod can toggle a hook end of the rod in a hook receptacle, which can change states of the locking mechanism. |
US10947087B2 |
Elevator safety system and method of operating an elevator system
An elevator system (1) comprises: a hoistway (4) extending between a plurality of landings (8, 9); at least one hoistway door (10, 11) allowing access to the hoistway (4); an elevator car (6), which is configured to move along the hoistway (4); at least one safety (16), which is attached to the elevator car (6) and configured to stop any movement of the elevator car (6) when activated; an electronic safety actuator (18), which is configured to activate and deactivate the at least one safety (16); and a door safety switch (20), which is configured to monitor the at least one hoistway door (10, 11) and which is connected with the electronic safety actuator in order to allow activating the at least one safety (16), if the door safety switch (20) detects that the at least one hoistway door (10, 11) is not closed. |
US10947081B2 |
Apparatus for and method of folding and winding a band of non-woven fabric of a predetermined length
The present invention relates to an apparatus and a method for folding and winding a predetermined length of non-woven fabric used for the industrial production of moistened wipes. The apparatus for folding and winding a predetermined length of non-woven fabric from a roll wound on a core is mounted on a countertop, equipped with a housing, provided with a drive unit. Mounted on a hub (1) is a cylinder (2), to which eccentrically attached are rods (3) from which at a certain distance is mounted a linear feed (4). The hub assembly (1) with the cylinder (2) with the rods (3) and the linear feed (4) can be mounted vertically or horizontally. |
US10947075B2 |
Control apparatus and control method for controlling an image forming system, and storage medium
A control apparatus to control a system including an image forming apparatus and a sheet discharge apparatus. The control apparatus receives configuration information of the system, and discharge state information having a discharge destination and a stacking amount of sheets discharged by the sheet discharge apparatus, and job identification information of an image forming job of sheets to be picked up. The control apparatus generates a system configuration image based on the configuration information, generates a sheet bundle image based on the discharge state information, combines the sheet bundle image with the system configuration image based on the discharge destination, and displays them as combined. The sheet bundle image is displayed with a size corresponding to the stacking amount and a first sheet bundle image, which corresponds to the job identification information, and a second sheet bundle image, which does not correspond to the job identification information, are distinguishably displayed. |
US10947064B2 |
Pipe for transporting powder and method for transporting powder
An object of the present invention is to provide a technique in which deposition of powder during pneumatic transport can be inhibited by a pipe body having a simple structure. The present invention is a pipe for transporting powder including a transport path which has a portion formed by a curved pipe and through which pneumatically transported powder passes, and a blowing path through which a gas is blown into the transport path from an opening formed on an inner circumferential surface of the curved pipe, in which the blowing path blows the gas in a direction in which the gas blown into the transport path from the opening forms a swirling flow along the inner circumferential surface of the curved pipe. |
US10947062B2 |
Product-stacking and case-packing system and method
Techniques for product-stacking and case-packing are particularly adapted for product that is packaged in envelopes or flexibly-sided containers. Such products include may different types, such as foodstuffs, books, boxed goods, etc. In an example, a product-stacking and case-packing system may include a product-stacking assembly and a case-packing assembly. In the example, the product-stacking assembly may be configured with a plurality of pairs of flights, each pair of flights programmed to move according to operation of an associated pair servo motors, and programmed to receive and down-stack incoming product items into groups. In the example, the case-packing assembly may include a robotic arm and end-of-arm tool configured to grasp one or more groups of stacked product items, when pushed from the product-stacking assembly, and place each group of stacked product items in a case (e.g., a cardboard box). |
US10947058B2 |
Modular conveyor belt integrating lane dividers
A conveyor system integrates lane dividers to form a plurality of product lanes across a conveyor belt carryway while providing conduits enabling transverse fluid flow across the carryway. Each lane divider includes a body defining edges of adjacent conveyor belt lanes and hinge elements or other attachment means for integrating the lane divider into a modular conveyor belt. The body has lateral conduits to allow transverse fluid flow therethrough. |
US10947056B2 |
Adaptive roller conveyor
An adaptive roller conveyor for conveying objects, comprises a plurality of rollers and a control device, wherein the control device is connected with a sensor for detecting at least one parameter of an object, wherein at least one roller is connected with an adjustable brake device, wherein the brake device is connected with the control device, and wherein the control device is configured to control the brake device in dependence on the detected parameter to change the braking effect of the roller. |
US10947052B2 |
Conveyor system gearmotor with direct roller connection
A gearmotor assembly for use with a conveyor system has a rotatable conveyor roller extending laterally between spaced conveyor side rails. The gearmotor assembly includes an electric motor with a rotatable motor output shaft. The gearmotor assembly further includes a gear train drivingly connected to the motor output shaft. The gear train includes a train output shaft axially offset from the motor output shaft, with the train output shaft being drivingly connectable to the conveyor roller, so that rotation of the motor output shaft produces corresponding rotation of the conveyor roller. |
US10947049B2 |
Conveyor system with automated carriers
A conveyor system comprising a fixed, non-powered rail defining a conveyor path and an automated conveyor carrier (ACC) supported on the rail to be movable along the conveyor path. The ACC includes an on-board motor and an on-board electrical power source selectively powering the on-board motor to drive the ACC along the rail. The ACC may include a wireless sleep mode module operable to selectively shut off power to an on-board ACC controller. |
US10947047B2 |
Air-supported belt conveyors and systems and methods of using same
Disclosed herein are air-supported belt conveyors and independent conveyor subsystems that are selectively and independently designed to meet requirements that can change along the length of a conveyor, as well as from conveyor to conveyor. |
US10947042B2 |
Storage system with robot device
A storage system for storing product items includes a grid structure and a number of first storage bins configured to be stored in vertical stacks in the grid structure. Each first storage bin is configured to contain at least one product item. A vehicle is arranged to move horizontally at the top level of the grid structure, and further arranged to pick up, carry, and place the first storage bins at desired locations within the grid structure. The storage system further comprises a robot device comprising a movable arm with a picking mechanism in one end thereof. The robot device is configured to move a storage item between a first location and a second location by means of its picking mechanism. The first location is the location of a first storage bin stored in the storage grid. |
US10947040B2 |
Formed support member
A formed support member that is structurally steady and easy to manufacture is disclosed herein. The formed support member comprises a downwardly facing U-shaped body as a load bearing surface, and a first flat end and a second flat end for securing the member to support beams and resisting movement of the member with respect to the beams. The formed support member may comprise at least one hole through the flat ends which allows the formed support member to be universally fastened to different sized horizontal beams for different storage needs. |
US10947038B2 |
Thermal insulating structure
A thermal insulating structure includes: at least two retainers that protrude from a to-be-insulated surface exposed to a vacuum space; at least two first multilayer vacuum insulating sheets adjacent to each other with the retainers positioned therebetween, the insulating sheets covering the to-be-insulated surface; at least one second multilayer vacuum insulating sheet that extends between the retainers along a boundary between the first multilayer vacuum insulating sheets in a manner to cover the boundary; at least two third multilayer vacuum insulating sheets that are adjacent to each other with the retainers positioned therebetween, the at least two third multilayer vacuum insulating sheets covering the first multilayer vacuum insulating sheets and the second multilayer vacuum insulating sheet; and a keep plate that is fixed to the retainers and holds the first multilayer vacuum insulating sheets, the second multilayer vacuum insulating sheet, and the third multilayer vacuum insulating sheets. |
US10947034B2 |
Cartridge, machine and system for the preparation of beverages and process for manufacturing the cartridge
The cartridge (1) according to the invention comprises an envelope (2) having a first and a second end wall (4, 5) connected together by an annular lateral wall (6) and defining an inner chamber (7) containing a quantity or dose of a substance (S) for preparation of the beverage. The envelope (2) has at least one first and at least one second permeable wall (6a, 5) acting as an inlet for the introduction of a flow of water into the chamber (7) and as an outlet from it respectively for outflow of the beverage from chamber (7). Between the first and the second permeable walls (6a, 5) the envelope (2) has an outwardly projecting annular formation (3g). A portion of the permeable inlet wall (6a) for the introduction of water into the chamber (7) is made in the annular lateral wall (6) of the envelope (2). The annular formation (3g) extends from the second end wall (5) in a direction substantially opposite to the first end wall (4). |
US10947029B2 |
Flexible sheet dispenser
Disclosed is a dispenser useful for storing and dispensing sheet material comprising a flexible outer wrapper, which may be formed from a single piece of plastic, defining an interior space for receiving the sheet material to be stored and dispensed. The outer wrapper has a top surface and a first opening disposed thereon. The dispenser further comprises a dispensing panel disposed between the stack of sheet material and the outer wrapper. The dispensing panel may be formed from a semi-rigid material, such as paperboard having a bending stiffness greater than about 200 Taber Stiffness Units so as to provide the dispenser with some structural integrity and facilitate dispensing of the sheet material. |
US10947025B2 |
Insulated block packaging assembly
A packaging assembly includes first insulation blocks, second insulation blocks, and third insulation blocks, each insulation block arranged in contact with at least one other insulation block to define a void, the packaging assembly including at least one enclosure, the insulation blocks at least partially surrounded by the at least one enclosure. |
US10947022B2 |
Integrated carton and shipping container design and filling manufacture process
An integrated carton and container which includes a collapsible container and a plurality of cartons. The carton or cartons can be filled with a product or products while the carton or cartons remain integrated with the container. The carton and container are integrated in such a way that when the container is expanded into an open position, the carton or cartons correspondingly expand into an open position. The integrated carton and container may be integrated in such a way that the integrated carton and container may be filled with a product and closed on a single apparatus. |
US10947021B2 |
Packaging for powdered explosive-detection training aids and uses thereof
The present application is directed to a packaging for a powdered explosive-detection training aid which may include first and second opposing flexible sheets heat sealed together along less than a periphery thereof and defining a storage compartment therebetween, wherein an unsealed portion of the periphery defines an opening to the storage compartment, wherein at least a portion of the first opposing flexible sheet is a semipermeable material permeable to a vapor emitted from the powdered explosive-detection training aid, with the second opposing flexible sheet being impermeable to the powdered explosive-detection training aid vapor; and a sealing member, wherein the sealing member is secured to the first opposing flexible sheet and, in a closing position, covers the semipermeable portion of the first opposing flexible sheet. |
US10947012B1 |
Container with fill gauge
A container to hold contents therein is described with a gauge to indicate the level of contents in the container. The container can be a prescription container to store capsules, tablets, pills and the like. A label is affixed outside the container and is substantially opaque such that the interior is not visible through the label. The label including a vertical, transparent viewing window to see past the label, through the container wall to view the contents therein. The label includes indicia and indicators adjacent the window to indicate a time remaining for the supply of contents in the container or other characteristics of the contents. The time remaining can be calculated by the container volume and characteristics of the contents. |
US10947007B2 |
Retention packaging assembly
A retention packaging assembly includes a frame and two sheet assemblies. The frame includes a central panel, end panels, and two sets of wing panels. Each set of wing panels includes wing panels that are foldably coupled to the central panel and to one of the two end panels. The sheet assemblies include a sheet that is attached at its ends to slot panels. The slot panels of each of the sheet assemblies are selectively couplable to one of the set of wing panels. After an object is placed on a front of the central panel, the sheets of the sheet assemblies are located over the sides of the object. The sets of wing panels can then be folded to a back of the frame to cause the sheets to retain the sides of the object to the central panel. |
US10947003B2 |
Multivariable perforated adjustable height box and method
A multivariable perforated adjustable height box is provided with improved folding, bending, and separation of adjacent panels. The multivariable perforated adjustable height box may include a box, columns, rows, glue tabs, column scores, row scores, perforations, cuts, skips, and bundle breakers. Perforation patterns may be irregular, angled, shifted, or otherwise configured to increase usability, strength, and/or other aspects of the packaging. A method to produce a packaging device with improved folding, bending, and separation of adjacent panels using the multivariable perforated adjustable height box is also provided. |
US10947002B2 |
Reverse pressure can end
A can end includes a center panel, an annular portion disposed about the center panel, a chuck wall disposed about the annular portion, a curl extending radially outwardly from the chuck wall, the annular portion including a subsurface step. |
US10947001B2 |
Delaminatable container
A delaminatable container excellent in productivity is provided. According to an exemplary aspect, a delaminatable container, includes a container body having an outer shell and an inner bag, the inner bag delaminating from the outer shell and being shrunk with a decrease in contents, wherein the container body includes a bottom seal protrusion protruding from a bottom surface of a storage portion to store the contents, and the bottom seal protrusion is a sealing portion of, in blow molding using a cylindrical laminated parison provided with an outer layer constituting the outer shell and an inner layer constituting the inner bag, the laminated parison and is bent. |
US10947000B2 |
Labeller and method for agricultural bale press
A device and a method for attaching a label for identifying a bale to an elongate flexible object, wherein the device comprises storage means for the label and attachment means for attaching the label to the elongate flexible object, and wherein the label, on its edge, has an opening which is adapted to attach the label to the elongate flexible object. |
US10946999B2 |
Method and system for wrapping ties in a facemask manufacturing process
An automated system and method wrap the fastening ties around the body of a continuous stream of facemasks in a facemask production line. The facemasks are oriented such that each facemask has a leading pair of ties and a trailing pair of ties extending from a body in a conveying direction of the production line. At a wrapping station in the production line, the facemask body is subsequently clamped to prevent rotation of the body. The leading and trailing pairs of ties are grasped with a rotation device at each side of the conveyor that rotates around the body to wrap the leading and trailing pairs of ties to wrap around the body. |
US10946995B2 |
Egg transfer module having free-moving ejector, and associated systems and methods
An egg transfer module is provided. Such a device includes an egg securing device configured to grasp an egg. A free-moving ejector is associated with the egg securing device and configured to freely move in relation thereto. An abutment is provided in spaced relationship to the egg securing device. The free-moving ejector is configured to interact with the abutment to cause movement of the free-moving ejector with respect to the egg securing device, thereby displacing the egg from the egg securing device. Associated systems and methods are also provided. |
US10946993B2 |
Wrapping device for a machine for winding-up a web material, and a machine for winding-up a web material including the wrapping device
The invention relates to a wrapping device (300) for wrapping a band around a wound up roll (5″), characterised in:—a storage (301) for said band (303) to be wrapped around said wound up roll (5″),—a first conveyor (330) positionable adjacent said wound roll (5″), for conveying said band (303) to said roll (5″),—said first conveyor (330) comprising a cylindrical drum configured for rotation about an axis (W),—said drum (330) having a surface configured for receiving and transferring said band (303) to said wound up roll (5″) by a vacuum applied to said band (303) via apertures (331) formed in said surface. |
US10946991B2 |
Method for operating a tubular bag machine for producing bags having a transverse bottom seam and a transverse top seam different to the transverse bottom seam
A method for operating a tubular bag machine having a biaxially drivable transverse sealing device for producing tubular bags, a film sheet being closed by transverse bottom and top seams after having formed a film tube, an edge area of the film sheet forming a side fold using a side folder before forming the transverse bottom seam, and transverse top and bottom seams formed by adjacent tubular bags in one work step, said tubular bags formed in the draw direction having an alternating orientation, said side folder interacting with a stationary fold molding on the inner side of the film sheet, the minimal distance of the transverse sealing device to the fold molding alternatingly altered in the draw direction and being larger when producing the two transverse top seams than the minimal distance of the transverse sealing device to the fold molding when producing the transverse bottom seams. |
US10946988B2 |
Method and device for forming package bodies which are open on one side using an oscillating gripper
Described and illustrated is a device for at least partially unfolding package sleeves, having a magazine comprising a stack formed from package sleeves, wherein the package sleeves of the stack are folded flat around at least two folding edges extending in the longitudinal direction of the package sleeves and wherein a gripper is provided for gripping a side of the package sleeves facing away from the stack and for moving, in particular pulling, the package sleeves along a withdrawal transport path with the folding edges into grooves of at least one receptacle of a moulding station and wherein the grooves are spaced so that the folding edges of the package sleeves are spaced apart further in the magazine than in the grooves. In order to further prevent operational malfunctions and allow a more reliable and largely malfunction-free production of packaging bodies which are open on one side from package sleeves which are open on both sides, it is provided that a drive is assigned to the gripper and/or the grooves for moving the package sleeve section gripped by the gripper first along the withdrawal transport path across a groove plane which connects the grooves, then back against the withdrawal transport path across the groove plane, and then again along the withdrawal transport path across the groove plane. |
US10946987B2 |
Machine to manufacture cartridges for electronic cigarettes
A machine to manufacture cartridges for electronic cigarettes comprising a casing made of plastic material inside which a quantity of powdered tobacco is contained; the machine is provided with a drum which receives an orderly mass of empty casings, and feeds them to a filling station in which a quantity of powdered tobacco is inserted into each empty casing and a filling unit which is arranged in correspondence to the filling station for feeding a quantity of powdered tobacco inside each empty casing from above; the filling unit is provided with a first hopper for the collection of powdered tobacco and a plurality of discs among which a first disc defining a bottom wall of the first hopper; wherein, between the first disc and a second disc a plurality of compartments is defined, each designed to contain the quantity of powdered tobacco to be inserted into a respective casing from above; and wherein the first disc and the second disc are mobile relative to one another, so as to vary the volume of the compartments and the quantity of powdered tobacco contained inside them. |
US10946986B1 |
Mechanism for increasing jettison clearance
Embodiments of the present invention generally relate to a novel system, device, and methods for providing a one-way locking mechanism that changes the shape or stiffness of a structure. More specifically, embodiments of the present invention relate to a mechanism for increasing fairing jettison clearance. Embodiments of the present invention permit outward breathing displacement by the fairing, but reduce the inward breathing displacement by the fairing such that the fairing does not hit and damage the spacecraft or vehicle as it is jettisoned from the spacecraft or vehicle. |
US10946983B2 |
System for handling luggage and a method of handling luggage
A system and a manner of handling luggage items, such as in an airport where the luggage items are stored in a plurality of buffers, where the luggage items of one buffer are provided into one container which is configured for loading into and transport on airplanes. The luggage items may be sorted into the buffers so that e.g. high priority luggage items are stored in containers separate from containers holding lower priority luggage items. |
US10946981B2 |
Methods and systems of anchoring an unmanned aerial vehicle on a ground station
An unmanned aerial vehicle (UAV) ground station, comprising: a landing surface having a perimeter and a center; a plurality of pushers held above the landing surface by a plurality of linear actuators; at least one electro-mechanical connector attached to one of the plurality of pushers, mechanically adapted to be electrically connected to a compatible electro-mechanical connector of a UAV; and a landing detection controller adapted to instruct the plurality of linear actuators to move the plurality of pushers simultaneously from the perimeter toward the center when a landing event related to the UAV is detected. |
US10946979B2 |
Apparatus for controlling vehicle impact absorption systems and related methods
Apparatus for controlling vehicle impact absorption systems and related methods are disclosed herein. An example apparatus includes a predictor to generate a prediction of an impact event for a vehicle based on data received from sensors of the vehicle. The example apparatus includes an energy absorption allocator to determine an amount of vehicle energy to be absorbed by a crash protection system of the vehicle upon the impact event. The example apparatus includes a communicator to generate an instruction to activate the crash protection system based on the prediction and the amount of vehicle energy to be absorbed by the crash protection system and transmit the instruction to a controller of the crash protection system. |
US10946978B1 |
Systems and methods for conductive aircraft sensors
An airborne platform includes a body and a sensor device. The body includes a first material having a first flexibility. The sensor device is positioned inside the body, and includes an electric conductor. The electric conductor includes a second material that has a second flexibility that is less than the first flexibility. The sensor device is configured to output an output signal indicating whether the sensor device has undergone mechanical failure in response to a load applied to the sensor device that is greater than a load threshold. |
US10946976B2 |
Fluidic propulsive system and thrust and lift generator for aerial vehicles
A vehicle includes a main body and a gas generator producing a gas stream. At least one fore conduit and tail conduit are fluidly coupled to the generator. First and second fore ejectors are fluidly coupled to the at least one fore conduit. At least one tail ejector is fluidly coupled to the at least one tail conduit. The fore ejectors respectively include an outlet structure out of which gas from the at least one fore conduit flows. The at least one tail ejector includes an outlet structure out of which gas from the at least one tail conduit flows. First and second primary airfoil elements have leading edges respectively located directly downstream of the first and second fore ejectors. At least one secondary airfoil element has a leading edge located directly downstream of the outlet structure of the at least one tail ejector. |
US10946971B2 |
Inflation control system
An inflation control system includes a valve module and a controller. The valve module includes a first valve fluidly connected to a fluid source, a second valve fluidly connected to the first valve, and a pressure regulator fluidly connected to the second valve and an aspirator. The controller is in communication with the first valve. |
US10946964B2 |
Modular personal transportation system
A vertical landing of an aircraft is performed using the first battery where the aircraft is unoccupied when the vertical landing is performed, the unoccupied aircraft includes the first battery, and the unoccupied aircraft excludes a second, removable battery. In response to detecting that the second, removable battery is detachably coupled to the aircraft, a power source for the aircraft is switched from the first battery to the second, removable battery. After switching the switch power source, a vertical takeoff of the aircraft is performed using the second, removable battery, wherein the aircraft is occupied when the vertical takeoff is performed. |
US10946961B2 |
Unmanned aerial vehicle
The present disclosure provides an unmanned aerial vehicle (UAV). The UAV includes a main body; an inertial measurement unit (IMU) disposed in the main body; a mounting bracket for fixing the IMU; and a circuit board fixedly disposed at the main body and integrated with a plurality of functional modules. The IMU is fixed on the circuit board through the mounting bracket. |
US10946960B2 |
Anomalous payload detection for multirotor unmanned aerial systems
A modular unmanned aerial system (UAS) can be configured to detect an anomalous UAS configuration or operating condition, and to notify the user or inhibit further operation of the UAS in response to such a detection. An indication of the actual rotational speed of the motor or of the flight power needed to hold the UAS in a hover state may be compared to a predicted value based upon the expected UAS configuration. A variance between the actual values and the predicted values may indicate that the UAS is in an unauthorized configuration, which may be due to an unauthorized payload. The UAS may be a modular system, and may take into account authorized and attached modules in predicting the thrust required to hold the UAS in a hover state. |
US10946954B2 |
Variable-speed drive system for tiltrotor with fixed engine and rotating proprotor
A variable-speed gearbox for a tiltrotor with fixed engine and rotating proprotor includes an input shaft coupled to the respective fixed engine, an output shaft coupled to the respective proprotor; a high-speed clutch integrated into a high-speed gear train, the high-speed gear train having an input coupled to the input shaft and an output coupled to the output shaft; and a low-speed clutch integrated into a low-speed gear train, the low-speed gear train having an input coupled to the input shaft and an output coupled to the output shaft. The high-speed clutch and the low-speed clutch can be freewheeling clutches capable of disconnecting the output and the input of the respective gear train of the high and low-speed gear trains in an overrunning condition when the output rotates faster than the input of the respective gear train. The low-speed clutch can be permanently engaged. In accordance to some embodiments the variable-speed gearboxes may include an accessory drive. |
US10946951B2 |
Winglet and method of designing a winglet
An aircraft (5) including a wing (3) and a winglet (1) at the end of the wing, the winglet including: a root (7); a tip (9); a transition region (11) extending away from the root; and a wing-like region (13) extending from the distal end of the transition region to the tip. When the aircraft wing (3) is under the worst-case static loading, the tip of the winglet is located at the maximum spanwise extent of the winglet (1), but when the aircraft wing (3) is under the no-load condition, the wing-like region (13) is canted inboard such that the tip (9) of the winglet (1) is located inboard of the maximum spanwise extent of the winglet. |
US10946950B2 |
Controlled flight of a multicopter experiencing a failure affecting an effector
According to a first aspect of the invention, there is provided a method for operating a multicopter experiencing a failure during flight, the multicopter comprising a body, and at least four effectors attached to the body, each operable to produce both a torque and a thrust force which can cause the multicopter to fly when not experiencing said failure. The method may comprise the step of identifying a failure wherein the failure affects the torque and/or thrust force produced by an effector, and in response to identifying a failure carrying out the following steps, (1) computing an estimate of the orientation of a primary axis of said body with respect to a predefined reference frame, wherein said primary axis is an axis about which said multicopter rotates when flying, (2) computing an estimate of the angular velocity of said multicopter, (3) controlling one or more of said at least four effectors based on said estimate of the orientation of the primary axis of said body with respect to said predefined reference frame and said estimate of the angular velocity of the multicopter. The step of controlling one or more of said at least tour effectors may be performed such that (a) said one or more effectors collectively produce a torque along said primary axis and a torque perpendicular to said primary axis, wherein (i) the torque along said primary axis causes said multicopter to rotate about said primary axis, and (ii) the torque perpendicular to said primary axis causes said multicopter to move such that the orientation of said primary axis converges to a target orientation with respect to said predefined reference frame, and (b) such that said one or more effectors individually produce a thrust force along said primary axis. |
US10946945B2 |
Cutting device for propeller driven watercraft
A system for cutting marine grasses, weeds and other plant life to protect a propeller drive watercraft is disclosed. An adjustable, protective cutting edge to protect a propeller, drive shaft of a boat or other watercraft motor is further disclosed. A propeller protection device to mount upon a watercraft is further disclosed for optimizing the navigation of watercraft and reducing in-piloting maintenance of clearing plant matter from a propeller of a watercraft. |
US10946943B2 |
Modular inflatable and platform docking stations and method of construction therefor
An inflatable water-based motorised device docking station is described. The inflatable water-based motorised device docking station includes an inflatable tube configurable to form an open ended area to receive a water-based motorised device; a floor area coupled to a portion of the inflatable tube; and a ballast bag with dump attached to the floor area and configured to stabilise the inflatable water-based motorised device docking station. |
US10946934B2 |
Actuation device for a control cable for a bicycle gearshift
A bicycle control cable actuation device having: a casing, configured for fixing to bicycle handlebars, a cable-winding bush, on which the control cable is wound and which is angularly mobile in the casing about a main axis of the device, an indexing bush that is coaxial to and associated with the cable-winding bush to removably hold the cable-winding bush in predetermined positions that are angularly spaced from each other by predetermined indexing angles, a manoeuvring mechanism, operative on the cable-winding bush to rotate it in a first angular direction about the main axis of the device, to obtain an upward gearshifting; and, a predetermined circumferential clearance corresponding to a predetermined gearshifting extra-stroke angle is provided between the cable-winding bush and the indexing bush. |
US10946929B2 |
Operation apparatus
An operation apparatus includes a supporting element, an operation element including an arm whose basal end is rotatably supported by the supporting element and whose tip is provided with an acting element, and a return spring provided between the supporting element and the operation element, in which the return spring is housed in a compact manner without inviting an increase in the number of components. A return spring is provided between a first spring holder and a second spring holder. A supporting element is provided with a first side wall opposing the return spring in the lateral direction. An arm is provided with a second side wall opposing the first side wall and surrounding the return spring in conjunction with the first spring holder, the second spring holder, and the first side wall. |
US10946925B2 |
Multi positional rotary steering damper assembly
A hydraulic rotary steering damper with articulate linkage to enable mounting to a vehicle's steering mechanism coaxially, non-coaxially, or at an angle to the axis of steering rotation of the vehicle with the option of a hinged frame mount to attach to a vehicle's frame for the purpose of linking the steering damper to the vehicle's frame. |
US10946924B2 |
Folding bicycle and method of use
A folding bicycle and method for folding the folding bicycle is provided. The folding bicycle comprises a frame having a first end and a second end; a first wheel connected to the second end of the frame, the first wheel and the frame being located in a first plane; a fork having a first end and a second end, the second end of the fork pivotally connected to the first end of the frame thereby allowing the fork to pivot about the first plane; a second wheel connected to the first end of the fork, the second wheel and the fork being located in a second plane; a first pivot member having a first pivot axis to allow the first end of the fork to pivot towards the second end of the fork about the first pivot axis; a second pivot member having a second pivot axis to allow the first end of the frame to pivot towards the second end of the frame about the second pivot axis; and a third pivot member having a third pivot axis to allow the second end of the frame to pivot towards the first end of the frame about the third pivot axis. |
US10946923B2 |
Personal transport vehicle
A personal transport vehicle is provided capable of staying upright without the need for a stand by incorporating tires having an advantageous design combined with an overall lowered center of gravity. The personal transport vehicle further incorporates a hub and steering assembly configured within the front wheel of the vehicle, as well as a bake and propulsion means configured within the rear wheel of the vehicle. Finally, the personal transport vehicle is capable of being folded into a compact configuration, lending itself to ease of shipment, storage and transport. |
US10946919B2 |
Mudguard member for saddled vehicle
A mudguard member for a saddled vehicle covering above a rear wheel, a rear fender as a mudguard member is formed from fiber-reinforced resin. The rear fender has a surface provided with a resin-made reinforcing rib, the surface facing toward the rear wheel. The rear fender is formed in an elongated shape including: a vehicle attached portion that is arranged at a vehicle-front-side; and a length extension portion that extends from the vehicle attached portion toward the rear of the vehicle body. The length extension portion has a top panel and side panels that extend obliquely downward from both vehicle-widthwise sides of the top panel. The reinforcing rib includes: longitudinal ribs that extend from the vehicle attached portion to a vehicle-longitudinal center of the length extension portion; and transverse ribs that are arranged in a grip pattern in conjunction with the longitudinal ribs. |
US10946916B1 |
Assisted spring seat height optimization lift
An assisted spring seat height optimization lift device and method of use thereof is presented herein. The device is generally comprised of a seat frame attached to a scissor lift assembly that can be moved by engaging a releases mechanism attached to a lifting mechanism. The device is used to lift a handcycle user to a height that is manageable to transfer to a wheelchair independently without impeding the functionality of the handcycle. |
US10946913B2 |
Fender-to-grille turn signal relocation kit
An aftermarket vehicle turn signal assembly and a method of retrofitting the turn signal assembly to a grille of a vehicle are disclosed. The turn signal assembly enables users to customize their vehicles by repositioning a turn signal from a factory original fender location, for example, to an aftermarket opening formed on the grille. Using special drill templates designed for a specific vehicle, a user can locate a position for a hole, and later drill a hole into the grille of a vehicle. A user can then insert an aftermarket turn signal assembly into the hole, and secure the turn signal assembly to the grill. The user can then remove the factory original turn signal light source from the original fender location, and place the light source within the aftermarket turn signal assembly. |
US10946912B1 |
Chassis assembly for autonomous ground vehicle
A chassis and skin of a delivery Autonomous Ground Vehicle include an aluminum structure and polymer panels affixed to the AGV by fasteners. The panels are mutually overlapping. A method of assembly includes hooks and clips to put and hold the panels in place during assembly. |
US10946910B2 |
Downforce duct
A vehicle having an underside, the vehicle comprising a first duct configured to channel air from a first outlet at the underside of the vehicle to a second outlet away from the underside of the vehicle so that when the vehicle is in forward motion the underside of the vehicle in front of the first outlet is at a lower pressure than the underside of the vehicle behind the first outlet. |
US10946909B2 |
Retractable aerodynamic system for a motor vehicle
The invention provides a retractable aerodynamic system for a motor vehicle including a structure of the vehicle. The system includes at least one aerodynamic flap, a drive mechanism that can rotate the aerodynamic flap about a rotation axis, and at least one member for locking the aerodynamic flap in at least one indexed position with respect to the structure of the vehicle. The locking member is able to transmit forces experienced by the aerodynamic flap to the structure of the vehicle when the aerodynamic flap is locked in the indexed position. |
US10946908B2 |
Aerodynamic rear drag reduction system for a trailer
An aerodynamic drag reduction system includes a side panel configured to be coupled to a rear swing door to extend generally vertically at least partially along a height of a trailer and a top panel configured to be coupled to the rear swing door to extend generally horizontally at least partially along a width of the trailer. The drag system includes a cable system configured to connect the side and top panels to prevent upward movement of the top panel beyond its generally horizontal position. The cable system includes a first cable with a first end coupled to an inner surface of the side panel, and a second cable and a third cable each with a first end coupled to a bottom surface of the top panel. A second end of each of the first cable, the second cable, and the third cable is coupled together at a juncture. |
US10946903B2 |
Vehicle underbody structure comprising a transversal beam of varying resistance to plastic deformation
The vehicle underbody structure comprises a floor panel, at least one longitudinal beam extending in a longitudinal direction of the vehicle under said floor panel and at least one transversal beam extending in a transversal direction, substantially perpendicular to the longitudinal direction, above the floor panel, the floor panel extending transversally between two sides, the transversal beam comprising a transversal central end extending under a central area of said floor panel and a transversal side end extending at one of the sides of said floor panel, wherein the transversal beam comprising a central portion, extending between the central end and an intermediate part of the transversal beam, and an end portion, extending between the intermediate part and the side end, the resistance to plastic deformation of the central portion being greater than the resistance to plastic deformation of the end portion, and in that the intermediate part of the transversal beam extends upright of the longitudinal beam such that the end portion of the transversal beam extends transversally between the longitudinal beam and one of the sides of the floor panel. |
US10946895B2 |
Control system for vehicle
A vehicle control system is provided, which includes a steering angle detector configured to detect a steering angle of a steering wheel by the operator, the steering wheel is mounted on the vehicle, a speed detector configured to detect a traveling speed of the vehicle, a reaction-force generator configured to generate a reaction force of the steering wheel, and a controller. The controller includes a processor configured to execute a lateral acceleration calculating module to calculate a lateral acceleration based on the traveling speed and the steering angle, a rigidity characteristic setting module to set the reaction force so that a rigidity value that is a ratio of the reaction force to the steering angle increases as the lateral acceleration increases, and a reaction-force control module to control the reaction-force generator so that the reaction force becomes the reaction-force value set by the rigidity characteristic setting module. |
US10946893B2 |
Apparatus and method for detecting motor failure
The present disclosure relates to an apparatus and method for detecting a motor failure capable of detecting a motor failure using a position sensor and, when a motor failure is not detected using the position sensor, detecting a motor failure using a torque sensor. An apparatus for detecting a motor failure according to an embodiment of the present disclosure includes a plurality of position sensors each configured to output signals related to a position of a motor, a torque sensor configured to detect torque of the motor according to rotation of a steering wheel, and a failure detector configured to, when all of the signals related to the position of the motor which have been output from the plurality of position sensors indicate that the motor is stuck, detect whether the motor has failed by using a variation of the torque of the motor. |
US10946889B2 |
Retractable steer-by-wire steering column
A steering column for a vehicle includes a telescopic mechanism, a first electrically powered linear actuator, and a means for absorbing the impact energy transmitted between a driver and the steering wheel in a crash. The telescopic mechanism includes substantially coaxial first and second tubular members. The first electrically powered linear actuator controls the longitudinal position of the first tubular member relative to the second tubular member. The means for absorbing the impact energy includes: (1) two or more folded metal straps; (2) at least one strap is fixed at one of its ends to a member which is fusibly connected to the first tubular member and to which is also connected a moving part of the said electrically powered linear actuator; (3) an adjacent edge of each of at least the first and second straps comprising an array of teeth or ramps; and (4) a pyrotechnically actuated means. |
US10946885B2 |
Multi-function pet stroller
A pet stroller includes a frame body. The frame body includes two rear wheel struts, two front wheel struts pivotally coupled with the two rear wheel struts respectively, a U-shaped handle frame coupled on the two rear wheel struts respectively, and a supporting frame assembly operatively connected with the two front and rear wheel struts. The supporting frame assembly includes an folding frame operatively cooperated with the U-shaped handle frame and the rear wheel struts, an upper supporting frame coupled on the folding frame, a plurality of canopy bars pivotally coupled with the folding frame, and a platform frame pivotally coupled with the folding frame, wherein a carriage body is supported by the frame body to provide a resting cavity for accommodating the animals and a canopy body is adapted to cover and enclose the resting cavity of the carriage body. |
US10946883B2 |
Train detection system for a railway track, a method for detecting a train on a railway track, and a controller for a train detection system for detecting a train on a railway track
A train detection system for a railway track defines a first lateral side and a second lateral side opposite the first lateral side. Two cameras are arranged along the railway track spaced apart from each other. Each camera is placed on either the first lateral side or the second lateral side. The system includes at least one passive target. Each of the passive targets is placed within the field of view of at least one of the cameras and on the opposite lateral side of the railway track with respect to the at least one of the cameras in whose field of view the respective passive target is placed. The system also includes at least one controller adapted to recognise the passive target in the images provided by at least one of the cameras to the controller to determine whether a train is located on the railway track. |
US10946878B1 |
Wireless slide fence system and method
A Wireless Slide Fence utilizing signal reflection technology to detect rockslides and can determine the size and location of fallen rocks/objects impeding travel along a train track is presented. The present disclosure solves the technological problem of determining rock size and location to validate rockslide/fall alarms to reduce false alarms, while minimizing repairs required by conventional systems through the use of obstacle detection units and vital logic controllers. The present disclosure improves the performance of the system by, generating validated alarms when fallen rocks/objects satisfy the size criteria and are located in an area hazardous to train operations. In one exemplary embodiment, a loitering time can be implemented to validate object detections to reduce false positives due to transient objects such as migrating animals. |
US10946876B2 |
Connected transportation network system
Disclosed is an interconnected transportation network system, wherein same is related to the field of transportation facilities and control, and comprises a main transportation system, a transfer system and an entry/exit system. The main transportation system is formed of a closed annular rail vehicle, and the annular train moves continuously on a T-shaped track to fulfil a passenger transportation task by means of multi-point drive. The transfer system (intercommunication) is of the same structure as that of the main transportation system, and the passengers transfer between main transportation lines by means of the transfer system. The entry/exit system (terminal) is formed of an annular buffer vehicle system and a stepping speed control system, and the passengers enter or exit the main transportation lines in a self-service manner by means of the entry/exit system. |
US10946873B2 |
Distracted driving elimination system
A distracted driving elimination system includes an image capture device within a passenger compartment of an automobile capturing images of a first hand and a second hand of a vehicle operator and a steering wheel. An analysis unit has a geometry and visual characteristics of multiple predetermined items saved in a memory. The analysis unit receives the images and compares the images to the predetermined items saved in the memory to identify if any one of the first hand or the second hand of the vehicle operator is not in direct contact with the steering and is in direct contact with one of the predetermined items thereby initiating a distracted driving event. A distracted driving signal is generated when the distracted driving event is initiated. An indication system generates an indication when the distracted driving signal is forwarded, the indication alerting the vehicle operator of the distracted driving event. |
US10946869B2 |
Vehicle steering control systems and methods
According to the present disclosure, a system for providing steering control in a dual path machine includes a propulsion controller operatively connected to plants of the machine for driving ground contacting elements, the propulsion controller being configured to control steering of the dual path machine through drive signals sent to the plants, and a brake controller operatively connected to left and right brakes of the machine, the brake controller being configured to control steering of the machine by providing differential brake pressures to the left and right brakes. The system of the present disclosure provides redundant steering control by receiving an input signal at the brake controller with an indication of steering position, receiving an input signal at the brake controller with an indication of brake position, and providing a differential brake pressure to brakes of the dual path machine based on the steering input signal and brake input signal. |
US10946859B2 |
Control apparatus and method for improving fuel efficiency in CACC system
Disclosed herein is a control apparatus and method for improving fuel efficiency in a CACC system, which can improve fuel efficiency through control of a vehicle speed so that a vehicle travels using an optimized cost in consideration of a target vehicle speed, current vehicle speed, minimum driving speed set in the vehicle, and a deceleration distance if the vehicle that uses the CACC system senses a forward vehicle and enters into a CACC active mode. The control method for improving fuel efficiency in a CACC system includes setting a target speed profile based on a target speed of the subject vehicle and an expected driving path, determining whether a target vehicle to be followed by the subject vehicle exists, and controlling the driving speed of the subject vehicle according to the set target speed profile depending on whether or not the target vehicle exists. |
US10946858B2 |
Travel control method and travel control apparatus
A travel control apparatus, when a lane line of the traffic lane that had been being detected is no longer detected, estimates an imaginary lane line based on the position of the lane line detected in the past and controls the travel of the host vehicle such that the host vehicle is at a predetermined position with respect to the imaginary lane line. |
US10946857B2 |
Geotagged and time stamped data secured by digital signature shared on private network
An autonomous vehicle and method for vehicle-to-vehicle communication is disclosed. The vehicle has a computer system capable of creating anonymous geotagged data and transmitting and receiving the geotagged data through a secured network for storage on a private cloud. The vehicle is equipped with a navigation system in communication with said computer and at least one sensor in communication with said computer system. The sensors are capable of creating data signals indicative of at least one of vehicle telemetry, travel visibility, and road conditions. The system includes a timer in communication with the computer system capable of creating a time stamp. The geotagged data can be used to control an automatic brake system and/or an autonomous driving system. |
US10946854B2 |
Control device of hybrid vehicle
A control device of a hybrid vehicle includes a power consumption calculating part configured to calculate power able to be consumed in the electric heating type catalyst, and a power supply control part configured to select a route for supplying the regenerative power to the electric heating type catalyst and supply the regenerative power to the electric heating type catalyst. The power supply control part is configured to supply the regenerative power to the electric heating type catalyst without going through the battery if the power able to be consumed in the electric heating type catalyst is equal to or more than a predetermined value, and supply the regenerative power to the electric heating type catalyst through the battery if the power able to be consumed in the electric heating type catalyst is less than the predetermined value. |
US10946847B2 |
Actuating device for a vehicle brake system
The actuating device for a vehicle brake system comprises a force input member, which can be coupled to a brake pedal, and a brake master cylinder. The brake master cylinder has at least one force transmission member. The force transmission member is coupled to the force input member in an articulating fashion. The force transmission member is positioned to transmit a force, which has been exerted onto the force input member, to the brake master cylinder. The actuating device has at least one elastically deformable positioning element. The at least one positioning element produces a holding force with which the at least one positioning element holds the at least one force input member in an installation position relative to the brake master cylinder. |
US10946838B2 |
Cleaning apparatus for sensor
A sensor apparatus includes a cylindrical sensor window defining an axis, and a tubular annular member fixed relative to the sensor window and substantially centered around the axis. The annular member includes a plurality of first nozzles and second nozzles arranged in an alternating pattern around the annular member. The first nozzles each have a direction of discharge in a radially inward and axial direction forming a first angle with the axis. The second nozzles each have a direction of discharge in a radially inward and axial direction forming a second angle with the axis, and the second angle is different than the first angle. |
US10946837B2 |
Wiper blade rubber
Provided is a wiper blade rubber which exhibits high adhesion to glass surfaces, excellent friction performance and excellent wiping performance, while being free from the occurrence of a bulge (blister) in a coating layer due to bleeding from a rubber substrate or blooming. A wiper blade rubber which has a lip part obtained by forming a coating layer on a rubber substrate by spray coating, and which is characterized in that: the coating layer is composed of a portion (A) that covers the rubber substrate and portions (B) that do not cover the rubber substrate; the portions (B) are a plurality of pores which are uniformly dispersed in the entire area of the coating layer and have diameters of 10 to 40 μm; and the ratio of the total area of portion (A) that covers the rubber substrate to the total area of the portions (B) that do not cover the rubber substrate is from 40:60 to 60:40. |
US10946831B2 |
Retractor pretensioner assembly
A seatbelt pretensioning retractor assembly for use in a vehicle is provided. The seatbelt pretensioning retractor assembly includes a housing adapted for being mounted to a frame and having an interior cavity, a pretensioner tube having an arcuate and curved shape, a sprocket rotatably mounted to the housing and fixedly coupled to a spindle, a rod disposed within the tube and a guide plate having a guide portion and a rod guide. The rod exits the tube along a perimeter of the sprocket, and toward an arcuate landing surface of the guide portion. In addition, the guide plate further includes a couple of tabs and ribs for avoiding rattling of the pretensioner tube in normal use of the retractor assembly. |
US10946822B2 |
Vehicle frame component
A vehicle frame component for limiting the movement of the wheel of the vehicle toward the cab of a cab on frame vehicle including a base member welded to openings in the frame side rail and extending outwardly and located proximal the wheel structure. In one embodiment the vehicle frame component is located forward of the wheel and includes a tire puncture device to deflate the tire during an offset front impact and in a second embodiment the vehicle frame component is located rearward of the wheel. The vehicle frame component has particular utility during an offset front impact where the offset is less than approximately twenty-five percent (25%) of the width of the vehicle. |
US10946820B2 |
In-vehicle detection system and power supply system and power supply controller
The present disclosure discloses an in-vehicle detection system and power supply system and power supply controller, which relates to the power supply control field. The power supply system comprises a low-power generator; a battery pack for supplying power to the in-vehicle detection system; a charger electrically connected to the low-power generator and the battery pack, respectively; and a power supply controller electrically connected to the battery pack and the low-power generator, respectively. |
US10946819B2 |
In-vehicle system
An in-vehicle system includes a power supply box provided in a vehicle, and having a plurality of device connectors and a controller that supplies, to the plurality of device connectors, power received from a power supply, and a switch that switches between a cut off and a permission of power supplied to the plurality of device connectors in the power supply box. When power supplied to the device connectors is permitted by the switch, the controller performs a connection target validation process of identifying a type of a connection target device connected to each of the device connectors and a position of the device connector to which the connection target device is connected. |
US10946817B2 |
Wire harness fixing structure
A wire harness fixing structure includes; a silencer disposed between a floor mat and a body in a vehicle; a wire harness disposed along a main surface of the silencer; and a fixing member fixing the wire harness to the silencer. A bottomed hole having a bottom is formed in the silencer to be concaved from the main surface in a thickness direction. The fixing member is locked to the bottomed hole, thereby fixing the wire harness to the silencer. |
US10946811B1 |
Vehicle-mounted mobile phone holder
A vehicle-mounted mobile phone holder includes a holder body, and a fixing base, the fixing base is connected with the holder body and cooperates with a slot for placing water cup on the side of the driving position. The disclosure adopts the design of a fixing seat, which places the fixing seat in a slot for placing water cup, and fixes the holder through the slot for placing water cup, which greatly facilitates the fixing of the holder. At the same time, this solution also designs a size adjusting sleeve to adjust the size, the design of the sleeve makes the holder suitable for different models, moreover, the product can be rotated 360 degrees around the slot, which greatly facilitates the use of the user. |
US10946806B2 |
Mesh pocket for vehicle
A mesh pocket for a vehicle includes a net member, a plurality of hook clips provided on a front face of an interior material, and a fixing member fixing part of the net member to the interior material. In a state in which corner parts of the net member are latched on the plurality of hook clips, part of a lower side of the net member is fixed to the interior material by the fixing member. Accordingly, even when the net member is detached from the hook clip when not in use, due to part of the net member being fixed to the interior material there is no possibility that it will be lost and, moreover, since a shopping bag, etc. can be hung on the hook clip, from which the net member is detached, the convenience can be improved. |
US10946799B2 |
Vehicle vision system with overlay calibration
A vision system of a vehicle includes a camera disposed at the vehicle and having a field of view exterior of the vehicle. The camera includes an imager and a processor that is operable to process image data captured by the imager. A video display screen is operable to display video images derived from image data captured by the camera. The processor generates a graphic overlay for display with the video images at the video display screen. The processor calibrates the graphic overlay by adapting the view orientation and position of the displayed video images utilizing a spatial transform engine to adapt the view orientation and position to a corrected position and orientation. |
US10946796B2 |
Overhead console button carrier having a unitary body
An overhead console button carrier has a unitary body. That unitary body includes a first light collimator, a second light collimator, a first intrusion sensor bracket, a second intrusion sensor bracket, a third intrusion sensor bracket and a plurality of button guides. A method and mold assembly for making the overhead console button carrier is also provided. |
US10946795B2 |
System for detecting surrounding conditions of moving body
Systems for detecting the surrounding conditions of a moving body are provided. An example system includes a plurality of lighting devices installed inside the moving body and a sensor configured to detect the surrounding condition. The system is configured to forcibly change the state of at least one of the plurality of lighting devices (change from an unlit state to a lighting state or a blinking state, change in the emission color, or change in the luminance) when the sensor detects an object, to which attention must be paid during traveling of the moving body, in the surroundings of the moving body. |
US10946786B2 |
Device combining stop lamps and cargo lamps
A lighting device for a motor vehicle, the lighting device including a vehicle stop-lamp assembly and a cargo-lamp assembly. The lighting device includes a common lens that is configured, on the one hand, to form at least one stop-lamp light beam and, on the other hand, to form at least one cargo-lamp light beam. It furthermore includes a first group of light sources that are configured to emit stop-lamp light beams and a second group of light sources that are configured to emit cargo-lamp light beams, the light sources of the first group and of the second group being arranged on a common electronic holder. |
US10946781B2 |
Vehicle floor mat retainer
A vehicle floor mat retainer includes a vehicle carpet portion including an engagement portion connected by a first hinge to a carpet retainer portion, and a vehicle floor mat portion including a cap portion connected by a second hinge to a floor mat retainer portion. |
US10946780B2 |
Locking rotatable handrail for stairs
A handrail assembly comprising a top bracket and a handrail pivotally connected to the top bracket. The handrail is movable relative to the top bracket between a stowed position and a deployed position. The handrail is able to be locked in position. The handrail can move between the stowed position and the deployed position when the handrail is not locked in position, but held in the stowed position or the deployed position when the handrail is not locked in position. The handrail cannot move between the stowed position and the deployed position when the handrail is locked in position. |
US10946779B2 |
Vehicle seat
A vehicle seat includes a seat cushion, an ottoman, and an energy absorbing portion. The ottoman is provided at a seat front side end portion of the seat cushion and is changeable between an unfolded position and a stored position. The ottoman, at the unfolded position, is adapted to support, from a seat lower side, calves of the passenger seated on the seat cushion, and the ottoman, at the stored position, is apart from the calves of the passenger seated on the seat cushion. The energy absorbing portion is configured to, in a case in which a load, which is inputted to the ottoman at the stored position toward a seat rear side, exceeds a predetermined value, absorb kinetic energy inputted to the ottoman while permitting displacement of the ottoman toward the seat rear side. |
US10946775B2 |
Vehicle seat storage system
A vehicle seat storage system includes a passenger seat including a seatback and a seat base. The seat has a seating condition where the seat is releasably attached to a floor of the vehicle and a stowed condition where the seat is unattached from the floor and the seat base is folded against the seatback. The seat includes risers pivotally attached to the seat base. The risers have a deployed position for supporting the seat base in the seating condition and a folded position where the risers are folded inwardly against the seat base in the stowed condition. An interior sidewall of the vehicle includes a recessed portion sized and configured to receive the seat in the stowed condition. The interior sidewall includes a guide configured to direct the seat in the stowed condition into and out of the recessed portion and support the seat in recessed portion. |
US10946771B2 |
Motor vehicle floor
A motor vehicle floor system includes an integral seat attachment point, and an over-molded seat attachment insert of a floor. The integral seat attachment point is provided on the seat attachment insert. |
US10946770B1 |
Vehicle safety system
A vehicle safety system including a vehicle assembly, a communication assembly and a seat assembly is disclosed. The vehicle assembly includes a vehicle having a diagnostics port and an onboard vehicle computer. The communication assembly includes a communication device that plugs into the diagnostics port. The communications assembly includes a microprocessor and a wireless communication module. The seat assembly includes a seat cushion and a weight sensor. A child is to sit on the seat cushion during transportation. Once the vehicle is shut off, the weight sensor determines if any weight above a predetermined threshold is detected. If weight is detected and the vehicle is shut off then it is assumed that the child was mistakenly left in the vehicle unattended and alerts within the vehicle, due to the onboard vehicle computer, and to a mobile device of a user, due to the microprocessor and wireless communication module, are activated. |
US10946769B2 |
Capacitive occupant detection system with improved discrimination capability
A capacitive seat occupancy detection and classification system with a capacitive sensor having at least two distinct antenna electrodes and a method of operating is proposed to reduce an impact of the sensor-to-object impedance ZSO on an object-to-ground impedance ZOG measurement that the system performs. By measuring the impedance between the different antenna electrodes by the system, additional information is obtainable that can be used to compensate the impact of the sensor-to-object impedance ZSO on the object-to-ground impedance. As one effect of combining both impedance measurement results, the proposed system is able to determine the object-to-ground impedance ZOG completely independent from wear of ISOFIX anchorages or human objects touching the electric ground of the vehicle, thus ensuring a stable classification of the object over the entire vehicle lifetime. The method further enables high-resolution seat occupancy classification. |
US10946768B2 |
Wireless and redundant vehicular mass detection systems and methods
A system may be integrated within or coupled to a vehicle, in a car seat, a seat cover, a pad, or another device. The system may determine placement of an object within the vehicle. When the driver parks and turns off the vehicle, the system may provide one or more visible or audible indicators to remind the user to check the back seat, trunk, or storage area of the vehicle. The audible indicators may utilize the speakers of the vehicle or the car horn. The visible indicators may include turning on or flashing interior or exterior lights, displaying information on a dashboard display or on a projected or augmented display on the windshield, and so on. In some instances, the system may send an alert to a smartphone, a key fob, another electronic device, or an emergency system to prevent overheating of an infant, a pet, groceries, and so on. |
US10946765B2 |
Vehicle and method for managing battery thereof
A vehicle and method are provided in which deterioration of a battery is controlled. The method includes detecting deterioration severity of the battery and determining whether the deterioration severity is equal to or greater than a reference value. A cause of battery deterioration is determined when the deterioration severity is equal to or greater than the reference value. The method further includes determining whether the cause of the battery deterioration is vehicle driving and reducing an SOC management range of the battery when the cause of deterioration of the battery is charging/discharging due to vehicle driving. The deterioration cause of the battery is determined as a state of the vehicle left unattended and the central SOC of the battery is adjusted when the cause of deterioration of the battery is not charging/discharging due to vehicle driving. |
US10946764B2 |
Controller for vehicle
A controller is applied to a vehicle including an engine (11) and a motor generator (12 and 13) as power sources of the vehicle and a battery (20) that transfers power with the motor generator. The controller charges the battery with a regeneration power that is a power regenerated by the motor generator when the vehicle is decelerated. The controller includes a SOC prediction unit (39, 50 and 205) to predict a SOC indicating a remaining capacity of the battery in a scheduled travel route of the vehicle, based on a predicted result of a road grade and a vehicle speed in the scheduled travel route, a discharge control unit (39, 52, 206, 208 and 301 to 303) to execute a discharge increasing control to previously increase a discharge quantity of the battery to prevent the battery from becoming in a saturation state based on a predicted SOC that is the SOC predicted by the SOC prediction unit, when the discharge control unit determines that the battery becomes in the saturation state where the battery cannot be charged with the regeneration power based on the predicted SOC, a determination unit (39 and 105 to 109) to determine whether a behavior of the predicted SOC shifts from a behavior of an actual SOC or determine whether a SOC shift factor occurs, after a start of the discharge increasing control, where the SOC shift factor is a vehicle control or an environment change that predicts the behavior of the predicted SOC shifts from the behavior of the actual SOC, and a correction unit (39, 110, 201 to 209 and 301 to 303) to correct the discharge increasing control by executing a prediction of the SOC in the scheduled travel route again, when the determination unit determines that the behavior of the predicted SOC shifts from the behavior of the actual SOC or determines that the SOC shift factor occurs. |
US10946761B2 |
Battery management device, vehicle having the same, and method for controlling the vehicle
A battery management device for preventing a battery from being damaged by a low voltage includes a storage configured to store a first protection voltage and a second protection voltage corresponding to a protection mode of the battery; a voltage detector configured to detect a voltage of the battery; a controller configured to confirm the detected voltage, to enter the protection mode when the detected voltage of the battery is the first protection voltage, to check a time point when the detected voltage of the battery is the second protection voltage, and to release the protection mode when a predetermined time elapses from the time point. |
US10946760B2 |
Remote indicator of state of charging of electric vehicle
A remote visual indicator of a state of charging of an electric and/or plug-in hybrid electric vehicle (EV and PHEV). In one or more embodiments, the aforesaid visual indicator incorporates a multi-color light source, such as a multi-color LED and uses the color of the emitted light to indicate the state of the EV/PHEV charging. In one or more embodiment, the aforesaid visual indicator incorporates one or more buttons or other user-activated controls configured to alter the charging of the EV/PHEV by the charging stations. In one or more embodiments, a sound generation element may be additionally provided for creating audible indicators of charging state. |
US10946759B2 |
Information providing method, information providing system and terminal each for electrically powered vehicle
A plurality of charging stations and a plurality of commercial facilities where a user of a vehicle can stay during charging in one of the plurality of charging stations are provided. An information providing method for the vehicle includes: causing a charging server to select a plurality of candidates from among the plurality of charging stations in accordance with location information about each of the vehicle and the plurality of commercial facilities; causing the charging server to provide a car navigation device with information showing the plurality of candidates selected; causing the server to deliver an advertisement for a commercial facility associated with each of the plurality of candidates selected; and causing the charging server to receive information about a candidate selected with the car navigation device from among the plurality of candidates by the user referring to the advertisement. |
US10946757B2 |
Contact apparatus and charging contact unit, and method for electrically connecting a vehicle to a charging station
The invention relates to a contact apparatus (11) and to a charging contact unit (12) for a rapid-charging system for electrically driven vehicles, in particular electric buses or the like, and to a method for forming an electrically conductive connection between a vehicle and a stationary charging station, wherein the contact apparatus serves to form an electrically conductive connection between the vehicle and the stationary charging station comprising a charging contact unit, wherein the contact apparatus can be arranged on a vehicle, wherein the contact apparatus comprises a contact device (14), wherein the contact device can make contact with the charging contact unit, wherein the contact apparatus or the charging contact unit comprises a positioning device (15), wherein the contact device can be positioned relative to the charging contact unit by means of the positioning device, wherein the contact device has a contact element support (16) comprising contact elements, wherein the contact elements can make contact with the charging contact elements of the charging contact unit so as to form contact pairs, wherein the contact elements are arranged on the contact element support relative to the charging contact elements in such a manner that a defined order is maintained when forming contact pairs when the contact device and the charging contact unit are joined. |
US10946756B2 |
Bidirectional integrated charger for a vehicle battery
A vehicle includes an integrated power distribution module. The integrated power distribution module includes a hybrid transformer coupled to a charger stage, a traction battery, and an auxiliary battery. The hybrid transformer includes first and second primary windings coupled in series and connected to the charger stage. The primary windings have a corresponding first secondary winding coupling the traction battery via associated inverters. The primary windings further have corresponding second secondary windings that are coupled in series with opposing voltage polarities and coupled to the auxiliary battery via an associated inverter. |
US10946742B2 |
Vehicle speed calculating method and device and driver state monitoring system including vehicle speed calculating device
Vehicle speed calculating device and method and a driver state monitoring system including the vehicle speed calculating device are provided. The vehicle speed calculating device includes: a signal determining unit configured to receive raw data input from a raw data generating device connected to an input socket via a UART port and a GPIO port, to perform a validation test on two types of raw data received via the UART port and the GPIO port, to determine one type of raw data as valid raw data, and to output the valid raw data and signal type information generated to correspond to the valid raw data; and a vehicle speed calculating unit configured to receive the valid raw data and the signal type information and to generate vehicle speed information corresponding to a vehicle speed which is calculated by processing the valid raw data using a predetermined processing method to match the signal type information. |
US10946738B2 |
Vehicle fuel tank assembly
A vehicle fuel tank assembly includes a fuel tank and an electrically conductive top plate that closes and seals a fuel-fill opening in the fuel tank. The top plate includes electrical dissipation structures and features that allow for electrical charge dissipation of the fuel tank to an external structure such as the vehicle chassis. The dissipation structures include an electrically insulative carrier that is partially embedded in the top plate using an overmolding process, and an electrical conductor that is supported by the carrier. The electrical conductor provides an electrical connection between the top plate and the chassis that is independent of the fuel tank and the fuel tank mounting structure. |
US10946736B2 |
All-terrain vehicle
An ATV is shown having a radiator that is coupled to the frame forward of and a hood is rotatably coupled to the frame and having an open position providing access to the radiator and a closed position enclosing the radiator. |
US10946734B2 |
Profile strip for a motor vehicle and profile strip production method
A profile strip for a motor vehicle, in particular for a sealing assembly in a window or door area of a motor vehicle. The profile strip comprises a securing profile section that can be secured on a first part of the motor vehicle. The profile strip comprises a sealing profile section connected to the securing profile section, produced from a vulcanized rubber matrix and configured to allow relative movements with reduced friction between the profile strip and a second part of the motor vehicle. A contact surface of the sealing profile section that can be brought into contact with the second part is provided with an anti-friction coating that comprises an anti-friction coating matrix and anti-friction particles embedded in the anti-friction coating matrix that are produced from UHMWPE. The anti-friction coating matrix is a vulcanized EPDM matrix. |
US10946733B2 |
Rolling tarp enclosure system
A movable, tarp enclosure system includes a movable carriage having a main body and plural primary support wheels connected to the main body, at least one of the wheels being disposed at a first vertical level and at least one of the wheels being disposed at a being vertical level. The system also includes a support rail having a first and second support walls, the upper surfaces of which are respectively engaged by the carriage wheel(s) disposed at the first vertical level and at the second vertical level for movably supporting the movable carriage on the support rail. |
US10946728B2 |
Sun visor connector
A sun visor connector includes: a bracket attached to an attachment member; an arm portion rotatably supporting a sun visor main body and having an end inserted through the bracket to be rotatably arranged; a housing fixed to the bracket and arranged in a vicinity of the end of the arm portion inserted through the bracket; a connector terminal accommodated in the housing and connected to a counterpart terminal; an arm connection part provided in an elastically deformable manner on the connector terminal and connected to the end of the arm portion by a biasing force; an engaging portion including a projecting portion provided in the housing and a recessed portion provided in the bracket and engaged with the projecting portion; and a first restricting portion provided in the projecting portion and pressed against and abuts on the recessed portion in a deformation direction of the arm connection part. |
US10946727B2 |
Flexible elastic windshield retaining clip
An elastic integrally formed windshield retaining clip includes walls defining a frame channel to receive and retain a portion of an upright windshield frame, and walls defining a pane channel to receive and retain a portion of an edge of a windshield while the portion of the upright windshield frame is retained in the frame channel. The frame channel not only surrounds three sides of a windshield frame, but also surrounds the majority of the fourth side of the frame. Angled walls exert pressure against the retained edge of the windshield and the frame. |
US10946722B2 |
Heater device
A heater unit emits radiation heat caused by heat generated with a heat generation unit when energized. The heater device includes a contact detection unit having a contact detection region overlying the heater unit to detect a contact by an object on the contact detection region. The heater device includes a determination unit to determine, when a contact by the object on the contact detection region is detected by the contact detection unit, whether the contact is for a predetermined switching operation. A control unit stops energization of the heat generation unit when the determination unit determines that the contact is not for the predetermined switching operation. The control unit switches between a start and a stop of energization of the heat generation unit when the determination unit determines that the contact is for the switching operation. |
US10946720B2 |
Airflow control system
An airflow control system includes an air blower and an outlet door. The air blower is disposed on a front side in a vehicle traveling direction with respect to an inside of a cabin and disposed inside an engine compartment that houses a propulsion engine. The outlet door opens and closes an air outlet through which an air flow from an inside of the engine compartment is blown to another area on a rear side in the vehicle traveling direction with respect to the engine compartment. The air blower blows an air flow containing exhaust heat of the propulsion engine to the other area through the air outlet while the air outlet is opened by the outlet door. |
US10946719B2 |
Vehicle air-conditioning device
A vehicle air-conditioning device may achieve comfortable heating of a vehicle interior by starting a compressor, an indoor blower and heat generating means at appropriate timing. The vehicle air-conditioning device includes a compressor which compresses a refrigerant, a radiator disposed in an air flow passage to let the refrigerant radiate heat, a heat absorber which lets the refrigerant absorb heat, and an indoor blower which blows the air through the air flow passage. The vehicle interior is heated by heat radiated from the radiator. The vehicle air-conditioning device includes a heating medium-air heat exchanger of a heating medium circulating circuit disposed in the air flow passage to heat air supplied to the vehicle interior. On a basis of an outdoor air temperature, the timing to start the compressor, the indoor blower and the heating medium circulating circuit is controlled. |
US10946718B2 |
Air-conditioning unit of a vehicle
An air-conditioning unit of a vehicle for air-conditioning a vehicle interior may include a unit outlet for discharging air into the vehicle interior, an outside-air duct for an intake of outside air, and an air recirculation duct for recirculation of inside air from the vehicle interior. The air-conditioning unit may also include an outside-air shut-off element arranged in the outside-air duct, which in a closed position blocks a flow of outside air through the outside-air duct, and a recirculated-air shut-off element arranged in the air recirculation duct, which in a closed position blocks a flow of inside air through the air recirculation duct. The air-conditioning unit may further include a sensor device for detecting a property of air. On at least one duct of the outside-air duct and the recirculation duct, a bypass may be arranged which bypasses an associated shut-off element and is fluidically connected to the sensor device. |
US10946716B2 |
Vehicle temperature sensor systems
A vehicle having a system which includes at least one sensor contained therein. The systems utilizes conditional probability to determine if an occupant (i.e. child and/or animal) is in the vehicle in the absence of an adult. The system used conditional probability to predict the likelihood that a child and/or animal was left unsupervised within the vehicle. The system collects data from existing vehicle sensors (door sensor, weight sensor, seatbelt sensor, face detection sensor, input sensors or any other suitable sensor already imbedded within the hardware of the vehicle) and uses that data to assume if an adult, child and/or animal is present. A motion sensor and a temperature sensor (infrared camera) are further utilized to determine the presence of a child/animal and the temperature of a child. Input from the motion sensor and/or temperature sensor (infrared camera) are utilized to provide warnings or to take corrective measures. |
US10946714B2 |
Electrically driven vehicle
An electrically driven vehicle includes an electric motor, a power storage device, an air conditioner, a heat exchanger of a refrigerating cycle, a heater and a controller, the air conditioner includes an internal air suction port and the foot blowout port installed at a position close to the internal air suction port, and, when a remaining capacity of the power storage device exceeds a predetermined value, the controller operates the refrigerating cycle and the heater, and further, is switched to an internal air circulation in which conditioning air blown out of the foot blowout port is suctioned from the internal air suction port. |
US10946713B2 |
Heat circulation system for vehicle
A heat circulation system for a vehicle includes: an energy supply circuit that supplies heat energy supplied from a heat source to at least a vehicle cabin heater or a battery heater and cooler; and an energy absorption circuit that supplies cold energy supplied from a heat pump mechanism to at least a vehicle cabin cooler or the battery heater and cooler. The heat circulation system for a vehicle further includes a water circulation circuit, and the water circulation circuit includes at least one of a first heat exchanger that generates hot water by exchanging heat with the energy supply circuit and a second heat exchanger that generates cold water by exchanging heat with the energy absorption circuit. |
US10946712B2 |
Method for operating a vehicle with a fuel cell unit
A vehicle includes a fuel cell unit with which is associated a first coolant circuit, with a second coolant circuit associated with the interior of the vehicle, in which is held a coolant of lower temperature relative to the coolant of the first coolant circuit. Given higher demand for cooling capacity in the first coolant circuit, a valve is opened by a control device, independently of the heat demand in the second coolant circuit, to open a first connecting conduit between the first coolant circuit and the second coolant circuit, and thus, using a second connecting conduit, forms a common ring conduit for the first coolant circuit and the second coolant circuit with the accumulated coolant from the first coolant circuit and the second coolant circuit. |
US10946711B2 |
Vehicle twist axle assembly
The twist axle assembly includes a pair of trailing arms that are spaced apart from one another in a first direction. The twist axle assembly also includes a twist beam, which has an open shaped cross-sectional shape, that extends in the first direction between a pair of opposing end portions. The open cross-sectional shape of the twist beam includes a base and a pair of side walls. The end portions of the twist beam are fixedly attached with the trailing arms. A pair of beam reinforcements are fixedly attached with the trailing arms and with the base of the twist beam. The beam reinforcements are fixedly attached with the twist beam through at least one of fasteners, adhesives, resistance spot welding, cold metal transfer welding, laser welding, and brazing. |
US10946710B2 |
Systems and methods for alerting drivers of excessive tongue weight
A vehicle includes a suspension that includes a front suspension and a rear suspension, a trailer hitch configured to removably connect to a tongue of a trailer, at least one front suspension transducer configured to generate a front suspension displacement signal, at least one rear suspension transducer configured to generate a rear suspension displacement signal, and an electronic control unit. The electronic control unit is configured to receive the front suspension displacement signal, receive the rear suspension displacement signal, and generate an alert of an excessive tongue weight condition based on one or more of the front suspension displacement signal and the rear suspension displacement signal. |
US10946708B2 |
Bush device for eye section of leaf spring
A bush device for an eye section of a leaf spring applied to a suspension of a vehicle is disclosed. The bush device includes a first hollow bush that is configured to be inserted into the eye section, and a plurality of second bushes that are disposed adjacent to both side surfaces of the eye section, respectively. Each of the second bushes have an aperture that is formed at a central portion thereof, and a leaf spring fixing bracket into which the second bushes are inserted. |
US10946707B2 |
Supporting structure for shock absorber of suspension device and suspension structure of utility vehicle
A suspension structure of a utility vehicle includes: a shock absorber; and a trailing arm extending in a longitudinal direction of the utility vehicle. A lower end of the shock absorber is supported by a rear end of the trailing arm within a wheel as viewed in a side view of the utility vehicle. |
US10946706B2 |
In-wheel three-arm suspension for vehicles
An in-wheel suspension system includes an assembly with a main arm that is pivotally connected at a connection point on the main arm to a shaft point of a wheel, a first linkage unit pivotally connected at one end to a first end of the main arm, and a second linkage unit pivotally connected at one end to a second end of the main arm. At least one second end of the first linkage unit and at least one second end of the second linkage unit, that are not connected to the main arm, are pivotally connectable each to a reference frame at a defined distance between them, such as to form a substantially “Z” like shape. |
US10946705B1 |
Flight module for an aerial vehicle
A flight module includes a rotor and a rotor carrier. The rotor carrier includes an elongate, upstanding carriage rail, a carriage supported for movement along the carriage rail, an elongate rotor arm carrying the rotor and supported atop the carriage rail for pivotation, and an elongate strut pivotally mounted between the carriage and the rotor arm. The pivotation includes pivotation between alongside the carriage rail, where the rotor arm retentively carries the rotor in a stowage position, and overhanging the carriage rail, where the rotor arm retentively carries the rotor with a skyward-facing orientation in a flight position. With movement of the carriage along the carriage rail, the strut transfers loading between the carriage and the rotor arm for pivoting the rotor arm between alongside the carriage rail and overhanging the carriage rail, and thereby carrying the rotor on the rotor arm between its stowage position and its flight position. |
US10946704B2 |
Railroad trailer chassis
A railroad trailer chassis comprising two or more road axles, two or more rail axles operable to be moved between first and second positions, and a work unit. The railroad trailer chassis is operable to be driven or towed in a road mode when the two or rail axles are in their respective first positions. The railroad trailer chassis is operable to be driven or towed in a rail mode when the two or more rail axles are in their respective second positions. The work unit is operable to perform one or more railroad maintenance or operation functions when driven in the rail mode. |
US10946698B2 |
Tire
A tire including a circular tire frame containing a resin composition, the resin composition containing a polypropylene having a melting temperature of 160° C. or higher, an ethylene-propylene rubber, and a styrene-containing elastomer, in which a content of the polypropylene having a melting temperature of 160° C. or higher being 60% by mass or less with respect to the resin composition as a whole, and a content of a styrene component being 5% by mass or more with respect to the resin composition as a whole. |
US10946697B2 |
Tire provided with a tread comprising a diene elastomer, a thermoplastic elastomer and a thermoplastic resin having polyphenylene ether patterns
A tire comprises a tread, a crown with a crown reinforcement, two sidewalls, two beads, a carcass reinforcement anchored to the two beads and extending from one sidewall to the other, characterized in that the tread comprises a composition based on at least a diene elastomer, at a content of between 35 and 99 phr (parts by weight per hundred parts of elastomer), a thermoplastic elastomer, at a content of between 1 and 65 phr, and a thermoplastic resin comprising optionally substituted polyphenylene ether units, said thermoplastic elastomer being a block copolymer comprising at least one elastomer block of optionally hydrogenated butadiene/styrene random copolymer type and at least one thermoplastic block of styrene type. |
US10946692B2 |
Method and apparatus for manufacturing printing paper for decorative boards and method for manufacturing laminated structure
A method for manufacturing a printing paper for decorative boards is provided. The method includes the processes of: applying a resin-containing liquid comprising at least one of a resin and a resin precursor to a base paper for decorative boards; forming a print layer on or in the base paper which is not dried after the resin-containing liquid is applied thereto; and solidifying a liquid contained in the base paper having the print layer. |
US10946686B2 |
Fountain solution deposition apparatus and method for digital printing device
An intermediate roller positioned between a fountain solution vapor supply and an imaging member decouples fountain solution vapor deposition from the surface of the imaging member. The intermediate roller may be temperature controlled. A uniform layer of fountain solution condenses onto the surface of the temperature controlled intermediate roller regardless of the imaging blanket temperature. The fountain solution condensate layer deposited onto the intermediate roller splits and deposits a thin uniform layer of fountain solution liquid onto the imaging member surface. This liquid layer split may be independent of the temperature of the imaging member surface, resulting in a uniform layer of fountain solution on the imaging blanket for better imaging quality. Remotely locating the vaporizing chamber away from the imaging member prevents undesired heat transfer from a hot vaporizing chamber/baffle to the imaging member surface. |
US10946685B2 |
Solidifying water-based printing fluid
In one example, a process to solidify a water-based printing fluid printed on a substrate includes flushing nonvolatile solvent in the printing fluid into the substrate with the water in the printing fluid. |
US10946682B2 |
Color changing expiration indicator
A printer system includes a memory, a processor, and one or more printer heads. The processor determines a number of transmission layers and a number of barrier layers to use in a color changing expiration indicator based at least in part on a time period between a print date of the indicator and a received expiration date. The printer heads print a reactive layer onto print media, where at least a portion of the reactive layer is configured to migrate through the transmission layers. The printer heads also print the determined number of transmission layers and the determined number of barrier layers in alternation. The printer heads print a reactant layer that is configured to change color responsive to a reaction between the reactant layer and the reactive layer upon migration of the reactive layer through the transmission layers. The reaction is configured to occur on the received expiration date. |
US10946678B2 |
Vacuum transport having opening pattern allowing jetting of all nozzles to receptacle
A transport item moves in a process direction to transport sheets of media. The transport item is positioned between an inkjet printhead and a receptacle. The inkjet printhead has nozzles. The transport item has openings arranged in a pattern, the pattern of the openings is consistent along all of the transport item, and the pattern of the openings in the transport item aligns at least one opening with each of the locations of the nozzles as the transport item moves in the process direction. The nozzles eject ink through the openings to the receptacle when the nozzles are aligned with the openings. When controlling the nozzles to eject ink through the openings to the receptacle, a controller can control the nozzles to simultaneously eject ink on a sheet of media while ejecting ink through the openings to the receptacle. |
US10946675B2 |
Recording apparatus and method of controlling recording apparatus
A recording apparatus includes a recording head performing recording on a recording medium; a cassette on which the recording medium to be transported to the recording head is placed; and a transporting path for transporting the recording medium from the cassette to the recording head. In addition, the recording apparatus includes a medium thickness sensor obtaining thickness information by measuring a thickness of the recording medium in the cassette or the transporting path; a surface information acquisition section acquiring surface information of the recording medium in the cassette or the transporting path; and a determination section specifying a type of the recording medium based on the thickness information and the surface information of the recording medium. |
US10946674B2 |
Sequencing of loads using temperature
A sequence of loads within a system is determined during each of multiple time windows based on a determination of each load's temperature to a target value. The sequencing of the loads involves a determination as to whether the length of each time window is long enough to permit all of the loads to be sequentially activated in order to have their temperatures approximate the corresponding target temperatures. In some cases, the sequence of the loads is determined to be one that results in a monotonically changing power profile. |
US10946671B2 |
System for printing and stamping eggs on conveyor
Disclosed is a system for marking eggs by stamping and printing thereon. |
US10946669B2 |
Inkjet recording apparatus, inkjet recording method, and inkjet recording program
An inkjet recording apparatus includes: a recorder having a line head, the recorder ejecting ink through each of the ink ejection ports toward a recording medium; a mover that moves the recording medium and the line head relative to each other in a direction intersecting the arrangement direction of the ink ejection ports in the line head, and causes each pair of ink ejection ports of two adjacent head modules facing each other in the overlapping region to pass through a same place on the recording medium; and a recording controller that controls ink ejection operations of the plurality of head modules on the recording medium in accordance with dot data, and causes either of a pair of ink ejection ports of two adjacent head modules to eject ink to implement complementary ink ejection operations by the pair of ink ejection ports of the two head modules. |
US10946668B2 |
Production system
A production system acquires a plan of production of plural types of products to be produced through sequential attachment of prints, determines an order of production of the prints to be attached to the plural types of products, respectively, and produces the prints in the determined production order. |
US10946665B2 |
Determining an out-of-liquid condition
In one example, a method for determining an out-of-liquid condition of a liquid supply for an inkjet printer. The method includes acquiring, during printing, a sequence of data points, each data point comprising a differential liquid/air pressure at the liquid supply measured with a sensor and a corresponding cumulative amount of liquid delivered from the liquid supply. The method further includes generating a curve using the data points. The method also includes determining, from a predetermined characteristic of the curve, whether the out-of-liquid condition exists. The characteristic is independent of at least one of a gain and an offset of the sensor. |
US10946660B2 |
Liquid discharge apparatus and suction apparatus
An object of the present disclosure is to provide a liquid discharge apparatus capable of sucking liquid in a cap member while suppressing generation of bubbles by a suction assisting member detachable from a cap member. A liquid discharge apparatus includes a liquid discharge head (6) to discharge liquid from a plurality of nozzles, and a suction mechanism (8) to suck the liquid from the liquid discharge head (6). The suction mechanism (8) includes a cap member (30) to contact the liquid discharge head (6) and cover the plurality of nozzles while forming a space between the cap member (30) and the liquid discharge head (6), a suction pump (31) connected to the cap member (30) via a suction hole (31a) formed in a surface of the cap member (30) to reduce pressure in the space, a suction assisting member (32) to cover the suction hole (30a) and the surface in which the suction hole (30a) is formed in the cap member (30), the suction assisting member (32) including a surface that forms a suction path between the suction assisting member (32) and the cap member (30), and a first support (32a) to provide a gap (c1) between the surface that forms the suction path of the suction assisting member (32) and the surface in which the suction hole (31a) is formed. |
US10946659B2 |
Applying first and second weaving masks
A printing apparatus comprises a printhead and a controller. The printhead includes dies, each die comprising rows of nozzles, wherein, in an overlapping region, the rows of nozzles of two dies overlap in a first direction, in which a relative movement between the printhead and a print medium takes place during operation of the printing apparatus. The controller is to apply a first weaving mask to a first row of nozzles of a first die and a second weaving mask to a second row of nozzles of the first die, the second weaving mask being different from the first weaving mask, the weaving masks defining, independent of print data, which of the nozzles of the corresponding row are to be used for printing in the overlapping region. |
US10946656B2 |
Liquid ejection head and liquid ejection apparatus
A liquid ejection head includes a flow path substrate, a first plate having a nozzle, and a second plate. A flow path substrate includes a first communication path which passes through a flow path substrate in a thickness direction and has an opening on each of a first plate side and a second plate side, and a second communication path communicating with an opening on a first plate side of a first communication path at a first plate side and extending on the second plate side. A pressure chamber communicating with a first communication path and a first flow path through which a liquid flows into a pressure chamber are formed by a part of a second plate and a part of a flow path substrate. |
US10946655B2 |
Nozzle head and droplet application device
According to one embodiment, a nozzle head includes a nozzle plate, a piezoelectric element, an actuator plate, a fixing part, and a conductive part. The nozzle plate includes a plurality of nozzle holes. The piezoelectric element includes a plurality of first electrodes and a plurality of second electrodes provided alternately and a piezoelectric part provided between the plurality of first electrodes and the plurality of second electrodes. The piezoelectric element is provided for each of the plurality of nozzle holes. The actuator plate is provided on opposite side of the nozzle plate from a side to which the plurality of nozzle holes are opened. The fixing part is insulative and provided between each of a plurality of the piezoelectric elements and the actuator plate. The conductive part is conductive and provided between each of a plurality of the piezoelectric elements and the actuator plate. |
US10946653B2 |
Fluid ejection microfluidic device, in particular for ink printing, and manufacturing process thereof
The fluid ejection microfluidic device, has a substrate; a buried cavity within the first substrate; a membrane formed by the first substrate and extending between the buried cavity and a first main surface of the substrate; and an access channel extending through the substrate, laterally and externally to the buried cavity and to the membrane and isolated with respect to the buried cavity. A sealed actuation structure extends over the first main surface of the substrate. A containment layer, of polymeric material, extends over the first main surface of the substrate and forms a fluid containment chamber accommodating the sealed actuation structure. A nozzle body of semiconductor material closes the fluid containment chamber at the top and is traversed by an ejection opening, forming, together with the fluid containment chamber and the access channel, a fluidic path. |
US10946651B2 |
Fluidic die sense architecture
A fluidic die includes a sense architecture having a global sense block to provide an analog reference signal and an array of distributed sense blocks. Each distributed sense block is to receive a same set of addresses via an address bus and each is to receive a corresponding sense enable signal having an enable value or a disable value. Each distributed sense block includes an array of sensors, each sensor corresponding to a different address of the set of addresses and a sample circuit to apply the analog reference signal to the sensor corresponding to the address on the address bus when the corresponding sense enable signal has the enable value, and provide to the global sense block an analog sense signal from the sensor resulting from application of the analog reference signal. |
US10946648B2 |
Fluid ejection die fluid recirculation
A fluid ejection device includes a fluid ejection die to eject drops of fluid and a body to support the fluid ejection die, with the fluid ejection die including a fluid ejection chamber, a drop ejecting element within the fluid ejection chamber, and a fluid feed hole communicated with the fluid ejection chamber, and with the body including a fluid feed slot communicated with the fluid feed hole of the fluid ejection die. The fluid ejection device includes a micro-recirculation system to recirculate fluid within the fluid ejection die through the fluid ejection chamber, and a macro-recirculation system to recirculate fluid within the body through the fluid feed slot across the fluid feed hole of the fluid ejection die. |
US10946634B2 |
Transfer device, curing system and curing method
Embodiments of the present disclosure provide a transfer device, a curing system with the transfer device and a curing method using the curing system. The transfer device includes: a mount; a rotary stage mounted to the mount and configured to be rotatable about a first axis; and a rotary table mounted to the rotary stage and configured to be rotatable about a second axis. |
US10946632B2 |
Multiple layer interlayers having enhanced properties
Multiple layer interlayers comprising pairs of alternating polymer layers are provided, along with methods of making and using the same. Multiple layer interlayers according to embodiments of the present invention may include more than three polymer layers and may exhibit desirable acoustic and optical properties, which may make them suitable for use in various types of multiple layer panels, including safety glass for automotive and architectural applications. |
US10946630B2 |
Dual shell dental appliance and material constructions
Improved dental appliances and polymeric sheet compositions are disclosed. The polymeric sheet compositions are useful for making dental appliances having outer layers comprised of a material having a modulus of from about 1,000 MPA to 2,500 MPA (“hard”) and an inner core comprised of elastomeric material or materials having a modulus of from about 50 MPa to 500 MPa (“soft”), which exhibit improved flexibility and strength, and better stain and tear resistance than currently available materials and dental appliances. |
US10946625B2 |
Composition, imprinting ink and imprinting method
Disclosed is a silane-based composition for forming an imprinting ink for imprint lithography applications in which the crosslinking of the silanes in the composition is suppressed by the inclusion of a compound of Formula 3: wherein R9 is selected from the group consisting of C1-C6 linear or branched alkyl groups and a phenyl group, and wherein n is a positive integer having a value of at least 2. An ink may be formed by adding a PAG, photoinitiator or TAG to the composition such upon their activation, the crosslinking reaction is completed. An imprinting method using 10 such an ink is also disclosed. |
US10946624B2 |
Glass repair kit and method
A portable glass repair kit system and method, more particularly, for windshield repair for laminated glass and the like to provide an easy to use, highly portable, and economical glass repair kit. The glass repair kit does not require specialized equipment such as an injector, plugger device, suction cups, or require any additional tools or specialized knowledge of how to use the repair kit. The glass repair kit contains a resin which may be urged by a user through slight pressure after the glass repair kit is adhered over an impact point and any cracks thereby repairing a windshield in a more cost effective, time efficient, and user friendly way. |
US10946620B2 |
Interlayer film for laminated glass, and laminated glass
There is provided an interlayer film for laminated glass with which the flexural rigidity of laminated glass can be enhanced. The interlayer film for laminated glass according to the present invention has a one-layer structure or a two or more-layer structure and is provided with a first layer containing a polyvinyl acetal resin and a plasticizer, and the half-value width of the hydroxyl group of the polyvinyl acetal resin contained in the first layer is less than or equal to 250 cm−1 and the content of the plasticizer contained in the first layer relative to 100 parts by weight of the polyvinyl acetal resin contained in the first layer is greater than or equal to 5 parts by weight and less than 30 parts by weight, or the half-value width of the hydroxyl group of the polyvinyl acetal resin contained in the first layer is greater than 250 cm−1. |
US10946615B2 |
Coloring composition, dichroic dye compound, light absorption anisotropic film, laminate, and image display device
An object of the invention is to provide a coloring composition which can form a light absorption anisotropic film having an excellent dichroic ratio, a dichroic dye compound, a light absorption anisotropic film, a laminate, and an image display device. A coloring composition according to the invention contains a dichroic dye compound which has a Hansen solubility parameter of 17.5 or greater and has a structure represented by Formula (1), and a liquid crystalline compound. L1-A1-N═N-A2-N═N-A3-L2 (1) in Formula (1), A1, A2, and A3 each independently represent a divalent aromatic group which may have a substituent. Any one of A1, A2, and A3 represents a divalent thienothiazole group which may have a substituent. In Formula (1), L1 and L2 each independently represent a substituent. |
US10946614B2 |
Structural member
The invention relates to a structural member comprising: a core portion that defines at least one anchor point, the core having at least one surface, a fibre tow arranged in a closed loop on the surface of the core portion, the loop defining a boundary of a space which contains the at least one anchor point, and a protective shell formed from a woven fibre sheet material which covers the fibre tow, and in which the core, fibre tow and the protective shell are impregnated and bound together by a cured resin. The invention also relates to a method of constructing a structural member. |
US10946613B2 |
Field expedient textile repair patch
An apparatus and method of manufacture for a repair patch may include a fabric layer, a primer layer applied to the fabric layer, an adhesive layer applied to the primer layer, and a release liner applied to the adhesive layer. |
US10946611B2 |
Patinated or patina-ready metal transaction cards and manufacturing process
A non-provisioned card having a front side and a back side, and at least one visible surface that is patinated or activated to promote patination. |
US10946610B2 |
Decorative material
In a decorative material, a matting agent is added to, of a first gloss-adjusting layer and a second gloss-adjusting layer, one with lower gloss, where the matting agent has a particle diameter of 1.0 times or more the thickness of the gloss-adjusting layer with lower gloss. Accordingly, sufficient unevenness can be imparted to the surface of the gloss-adjusting layer; thus, glossiness does not increase in oblique observation, and low gloss can be maintained. Therefore, it is possible to provide a decorative material having a feeling of unevenness obtained by the difference in gloss that hardly changes even when observed obliquely. |
US10946607B2 |
Handheld tool
The application provides a blank for forming a handheld tool. The blank includes an elongated sheet that includes a top surface and a bottom surface, a first longitudinal end and a second longitudinal end, a first side end and a second side end, and a circumferential edge. The circumferential edge includes a rear edge, a front edge, a first side edge, and a second side edge. The elongated sheet also includes at least one upward bending line extending, and a second upward bending segment, and a connecting segment. The elongated sheet also includes a first downward bending line and a second downward bending line. |
US10946606B2 |
Machine for manufacturing inflated cushioning products
A machine for providing cushioning products of varying lengths from a supply of a web material having sequential transverse rows of inflated protrusions. A pair of opposing feed members form a feed nip for moving the web along a path of travel. At least one sensor detects location information for the sequential rows of inflated protrusions as the web travels along the path of travel. A severing device is moveable between (i) an engaged position to separate the web transversely or perforate the web transversely and (ii) a disengaged position. A controller is programmed (i) to receive the location information and (ii) to operatively control the severing device to move it to the engaged position when a selected row is in a determined position relative the severing device. |
US10946603B2 |
Bead core forming former
An annular bead core forming former is for manufacturing a bead core including a wire array in which a bead wire is helically wound in a width direction of the bead core. The bead core forming former comprises a main body portion having an outer circumferential surface with a circumferential groove extending in a circumferential direction for winding the bead wire and at least one width adjusting portion which moves relatively to the main body portion to changes a width of the circumferential groove. |
US10946602B2 |
Drum and method for assembling an adapter for mounting a tire on a wheel rim
A radially expandable building drum, in which is intended for manufacturing an adapter for mounting a tire on a wheel rim, includes a central shaft, a first set of segments, and a second set of segments. All of the segments are arranged circumferentially around the shaft to form a generally cylindrically shaped external face of the drum. The segments of the first set and the segments of the second set face one another axially. The drum is structured to allow a different radial expansion of the segments of the first set in relation to the segments of the second set, between two working positions. |
US10946598B2 |
Method of manufacturing a wind turbine blade
In a method for manufacturing a wind turbine blade half shell, a preformed and cured aerodynamic blade shell member 42 of a fibre reinforced resin is provided. A primarily uniaxial fibre material 66 comprising carbon fibre is laid up on a longitudinal inner area 50 of the preformed shell member 42 and then infused with a resin by vacuum-assisted resin transfer moulding (VARTM), where a longitudinal resin inlet channel 80,82 is arranged on a first lateral side 46 and a vacuum channel 86,88 is arranged on a second lateral side 48 of the laid-up fibre material, and the resin is infused in transverse direction from the first to the second lateral side 46,48. |
US10946594B1 |
Reinforced polymer-infused fiber composite repair system and methods for repairing composite materials
A method and associated system for repairing a reinforced polymer-infused fiber composite. The method includes providing a resin infusion device having resin components contained in a flexible, sealed container, positioning a dry fiber reinforcement onto a base layer repair location, providing at least one resin conduit connecting the resin container to a first end of the dry fiber reinforcement, providing at least one vacuum conduit connecting a vacuum source to a second end of the dry fiber reinforcement, covering and sealing the base layer repair location with a vacuum enclosure affixed to the base layer repair location, creating a vacuum environment at the base layer repair location via the vacuum conduit, infusing the dry fiber reinforcement with a reactive mixture of the resin components under vacuum conditions via the resin tubing to form a resin-infused fiber reinforcement, and curing the resin-infused fiber reinforcement inside the vacuum enclosure. |
US10946593B2 |
Heater system for fiber placement machine
Closed-loop systems and methods for controlling the temperature at the compaction point as an automated fiber placement (AFP) machine is placing material over complex surface features at varying speeds. The closed-loop system starts with multiple infrared temperature sensors directed at the layup surface in front of the compaction roller and also at the new layup surface behind the compaction roller. These sensors supply direct temperature readings to a control computer, which also receives speed data and a listing of active tows from the AFP machine and is also programmed with the number of plies in the current layup. In accordance with one embodiment, the heater control system uses a proportional-integral-derivative loop to control the temperature at the compaction point (e.g., at the interface of the compaction roller and a newly laid tow) and regulate the heater power to achieve the desired temperature. |
US10946592B2 |
Resistive heating-compression method and apparatus for composite-based additive manufacturing
A method and apparatus for resistive heating usable in composite-based additive manufacturing is disclosed. The method includes providing a prepared stack of substrate sheets, placing the stack between electrode assemblies of a compression device, applying a current to thereby heat the stack to a final temperature to liquefy applied powder, compressing the stack to a final height, cooling the stack, and removing the cooled, compressed stack from the compression device. The apparatus comprises at least two plates, a power supply for providing current, a first electrode assembly and a second electrode assembly. |
US10946588B2 |
Systems and methods for automated nozzle design and 3D printing
A present disclosure relates to a system for automatic design and manufacturing of 3D printing units and 3D products. The system is configured to obtain specification of a target structure corresponding to a 3D product; automatically determine a design and a printing path of a 3D printing unit based on the specification of the target structure, wherein the 3D printing unit is a micronozzle unit configured to print the target structure of the 3D product; automatically determine a manufacturing procedure to print the 3D printing unit based on the specification of the target structure; and instruct a 3D printer to print the 3D printing unit according to the manufacturing procedure and the printing path of the 3D printing unit. |
US10946581B2 |
Method for calibrating an apparatus for manufacturing a three-dimensional object
Method for calibrating an apparatus for manufacturing a three-dimensional object by layer-wise selective solidification of building material with the step of generating an substantially periodic first modulation pattern in a first sub-area of the build area, the step of generating an substantially periodic second modulation pattern in a second sub-area of the build area, wherein in the overlap zone, the first modulation pattern and the second modulation pattern form an substantially periodic superposition pattern, whose period is larger than the period of the first modulation pattern and the period of the second modulation pattern, the step of detecting the superposition pattern, and the step of determining the deviation of the position of the superposition pattern on the build area from a reference position. |
US10946580B2 |
Microporous membrane for stereolithography resin delivery
A system for building a structure. The system includes a reservoir; an immiscible fluid in the reservoir; a membrane operatively connected to the reservoir; channels and delivery ports in the membrane; a microliter amount of curable resin; a delivery system for delivering the microliter amount of curable resin to channels and delivery ports in the membrane and to the reservoir in contact with the immiscible fluid in the reservoir; and an energy source adapted to deliver energy to the reservoir onto the microliter amount of curable resin for building the structure. |
US10946579B2 |
Device fabrication using 3D printing
A fabrication process includes: 1) forming an object by 3D printing; 2) smoothing the object by applying a gel to the object to coat at least a portion of the object with a film of the gel; 3) subjecting the object coated with the film to vacuum; and 4) curing the film to yield the object coated with the cured film. |
US10946577B2 |
Imprinting apparatus
An imprinting apparatus includes a first frame, a pressure roller rotatably supported on a first end of the first frame, a second frame including a support portion coupled to a second end of the first frame, and at least one guide portion coupled to the support portion to be laterally movable, and at least one load roller supported by the at least one guide portion, the at least one load roller being movable in a vertical direction while being rotatable and contacting a surface of the pressure roller on an upper portion of the pressure roller according to a lateral movement of the guide portion, the at least one load roller to press the pressure roller by force exerted by a load of the at least one load roller. |
US10946576B2 |
PEX expanding tool
An expanding tool comprising: an actuator comprising a cylindrical housing that defines an actuator housing cavity; a primary ram disposed within the actuator housing cavity, the primary ram defining an internal primary ram cavity; a secondary ram disposed within the internal primary ram cavity; a cam roller carrier coupled to a distal end of the secondary ram; a drive collar positioned within a distal end of the actuator housing cavity; a roller clutch disposed within an internal cavity defined by an inner surface of the drive collar; a shuttle cam positioned between the roller clutch and a distal end of the primary ram; an expander cone coupled to the primary ram; and an expander head operably coupled to the drive collar. |
US10946573B2 |
Cassette mold type injection molding machine
The cassette mold type injection molding machine controls a first temperature control circuit to supply a heat medium having a heating temperature from a first heating device to a matrix supply path, controls a second temperature control circuit to supply the heat medium having a cooling temperature from a second heating device to the core cavity supply path, and performs cassette mold cool down control in which a bypass control valve is controlled to connect a bypass path and a main body supply path, such that a second heating device or a core cavity supply path is connected to a main body supply path, and thus the heat medium having the heating temperature is supplied to the matrix and the heat medium having the cooling temperature is supplied to a cassette mold main body and a core cavity portion. |
US10946567B2 |
Apparatus and method of forming connectors brackets for irrigation laterals along an already made lay-flat pipe
Apparatus and method of forming connector brackets for irrigation laterals along a prefabricated lay-flat pipe and lay-flat pipe with such connector's brackets, wherein an opening is formed at one wall of the premanufactured pipe, a separation means is positioned inside the pipe opposite the opening while separating the one wall from the second wall of the pipe, and an injunction molding is performed into a mold cavity, in order to form the bracket affixed to the one wall of the prefabricated pipe and around the opening. |
US10946566B2 |
Method for producing a part and associated gripping device
A method for producing a part includes the steps of: positioning an insert in a mold via a gripping element, able to be actuated between an inactive configuration and an active configuration, of a gripping device comprising a shaping wall; shaping the insert in a reinforcing element against a surface; during positioning, maintaining a separation between the surface and the insert, and moving the shaping wall to apply the insert against the surface; and during the shaping, applying the shaping wall and the gripping element against the insert and the surface, the element being actuated in its inactive configuration before the application of the shaping wall. |
US10946563B2 |
Expanding foam presence sensor and related methods
Various embodiments are directed to sensor apparatuses configured to detect the presence of foam forming composition in various regions within a foam dispensing apparatus. In various embodiments, the foam dispensing apparatus comprises a dispensing nozzle positioned between at least two container-forming layers and configured to dispense foam forming composition into a container interior formed by the container-forming layers. The sensing apparatus may be positioned external to the container interior, on an opposite side of a container-forming layer relative to the nozzle, and the sensing apparatus may be configured to detect whether foam forming composition is present within a field of view of the sensing apparatus, which encompasses a portion of the container interior. The sensing apparatus may comprise a contactless temperature sensor configured to detect the presence of foam forming composition based on the detected temperature of a surface within the field of view of the sensor apparatus. |
US10946558B2 |
Lamination molding apparatus
A lamination molding apparatus including a chamber covering a molding region; a laser beam source to emit a laser beam for sintering a material powder supplied on the molding region to form a sintered layer; and a scan unit to scan the laser beam. The laser beam has one or more spot shapes including at least an elongated shape, and the scan unit is configured to scan the laser beam, of which the spot shape is an elongated shape, in a lateral direction of the elongated shape, is provided. |
US10946553B1 |
Airborne dust mitigation system
A system for use with a gunite rig to capture airborne gunite type materials, particularly those containing silica, during the preparation of the gunite. In one respect, as the bags of silica-containing material are placed in the mixing section of the gunite rig and ripped open, airborne gunite dust is captured by a hood and suction system positioned above the mixer. Further, the mitigation system includes a plenum box and suction system positioned adjacent the mouth of a gunite pot to capture gunite dust generated as the mixed gunite material falls from a hopper into the gunite pot. |
US10946551B2 |
Methods of in-line extrudate inspection and feedback control for honeycomb body manufacture
In-line inspection and control system to in-situ monitor an extrudate during extrusion. A light beam illuminates a line on the outside circumference of the extrudate skin recording the curvature. A master profile of the illuminated defect-free skin is recorded and compared to successive monitoring of the illuminated skin. Differences from the comparison indicate skin and/or shape defects. A real-time feedback to automatically adjust process control hardware reduces or eliminates the skin and shape defects based on the monitoring and comparison. |
US10946533B2 |
Gripping tool, gripping system, and evaluation method of gripping performance
According to one embodiment, a gripping tool includes a gripper. The gripper is flexible. A granular material is provided in an interior of the gripper. The gripping tool grips a workpiece by depressurizing the interior of the gripper in a state in which the gripper is caused to contact the workpiece. The gripper includes a first portion contacting the workpiece, and a second portion opposing the first portion. The granular material is provided in a first space between the first portion and the second portion. A hardness of at least a portion of the first portion is less than 46.9. |
US10946529B2 |
Method and device for charging service robot and service robot
A method for charging a service robot and a service robot are disclosed. The method comprises: collecting an audio signal generated by a sound source of a charging pile; determining a direction of the sound source according to the collected audio signal; controlling a robot main body to move toward the direction of the sound source, to shorten a distance between the robot main body and the charging pile; judging whether the infrared receiver array has received an infrared pulse signal emitted by the infrared emitter array of the charging pile; and when the infrared receiver array has received the infrared pulse signal, controlling the robot main body to move toward a direction of the charging pile according to the infrared pulse signal, to engage a charging component of the robot main body with a charging contact element of the charging pile. |
US10946525B2 |
Robot control system and robot control method
A robot control system controlling a robot executing a personal service includes: a storage unit configured to store therein in advance trigger action information for which a task to be executed by the robot is formed by a series of actions and the actions and trigger conditions for respectively starting the actions are specified; a trigger determination unit configured to determine whether a trigger condition of the action is satisfied; an action execution unit configured to execute the action; and a task execution unit configured to sequentially select an action specified in the trigger action information of the task to be executed by the robot, cause the trigger determination unit to determine whether a trigger condition of the selected action is satisfied, and cause the action execution unit to execute the action when the trigger condition is satisfied. |
US10946523B2 |
Failure diagnostic device and failure diagnostic method
A failure diagnostic device includes a torque detector that detects disturbance torques applied to joint shafts included in a multi-axis robot, a torque grouping circuit that groups the disturbance torques according to a content of an operation executed by the multi-axis robot upon detection of each disturbance torque, a torque correction circuit that obtains a corrected disturbance torque standardized between a plurality of operations with different contents based on a representative value preliminarily set for each grouped disturbance torque and the disturbance torque detected by the torque detector, and a failure diagnostic circuit that performs a failure diagnosis on the multi-axis robot by comparing the corrected disturbance torque with a threshold. |
US10946519B1 |
Offline computation and caching of precalculated joint trajectories
Implementations are described herein for offline computation and caching of precalculated joint trajectories. In various implementations, an instruction may be obtained to move an end effector of a robot between start and target positions. A first type of trajectory planning may be performed in real time or “online” to calculate a first joint trajectory of the robot that moves the end effector from the start to target position. The robot may then implement the first joint trajectory. A second type of trajectory planning may be performed offline, e.g., during downtime of the robot, to precalculate a second joint trajectory of the robot to move the end effector from the start to target position. The second type of trajectory planning may require more resources than were required by the first type of trajectory planning. Data indicative of the precalculated second joint trajectory of the robot may be stored for future use. |
US10946515B2 |
Deep machine learning methods and apparatus for robotic grasping
Deep machine learning methods and apparatus related to manipulation of an object by an end effector of a robot. Some implementations relate to training a deep neural network to predict a measure that candidate motion data for an end effector of a robot will result in a successful grasp of one or more objects by the end effector. Some implementations are directed to utilization of the trained deep neural network to servo a grasping end effector of a robot to achieve a successful grasp of an object by the grasping end effector. For example, the trained deep neural network may be utilized in the iterative updating of motion control commands for one or more actuators of a robot that control the pose of a grasping end effector of the robot, and to determine when to generate grasping control commands to effectuate an attempted grasp by the grasping end effector. |
US10946512B2 |
Robot
A robot includes an arm having a cover, a first motor, a first amplifier having a first drive circuit that drives the first motor, and a plate provided in an interior of the arm, wherein the plate is provided with the first amplifier and separated from the respective first motor and cover. |
US10946510B1 |
Caulk caddy and corresponding method and system
A device for receiving and holding a plurality of objects comprises a main body having a plurality of chambers defined therein and a plurality of resilient tabs attached to or integral with the main body and spaced about a perimeter of the main body. Each chamber has an open top end and is adapted to receive at least one object via its open top end. Each tab is adapted to support the device on a top rim of a bucket such that the main body is elevated off a floor of the bucket. Each tab is adapted to flex inward toward a longitudinal axis of the main body when a downward force is applied to the main body such that the main body and the tabs move downward into the bucket until the main body contacts the floor of the bucket. |
US10946501B2 |
Tool system
A multi-purpose hand tool system is described. The tool system includes a handle and one or more inserts that are releasably engaged with the handle. The tool system is useful for a variety of applications including use with basin and faucet hardware. |
US10946491B2 |
Movement error identification method for machine tool
A motion error of a machine tool in a coordinate system having its origin at an arbitrary position is identified by means of error data measured by a commonly-used method. An X-axis feed mechanism, a Y-axis feed mechanism, and a Z-axis feed mechanism are operated in a three-dimensional space of a machine coordinate system to measure translational errors, angular errors, and perpendicularity errors thereof, and error data for translational error parameters, angular error parameters, and perpendicularity error parameters in a three-dimensional space of a set coordinate system having its origin at a preset reference position Xa, Ya, Za are derived based on the measured actual error data. Subsequently, a relative motion error between a spindle and a table in the three-dimensional space of the set coordinate system is derived based on the derived error data. |
US10946489B2 |
Material support systems, material support structures, and related methods
A core support system includes a support structure. The support structure includes a frame and a support member having a saturatable engagement layer disposed over the frame. A method of machining a core material includes applying a fluid to an engagement layer of a support structure and saturating the engagement layer with the fluid, disposing a core material on the engagement layer, causing the fluid to freeze to secure to the core material to the support structure, machining the core material, melting the frozen fluid to release the core material from the support structure, and removing the core material from the engagement layer. |
US10946485B2 |
Method for welding two components
A method for welding two components is provided. The method includes providing a first component, which has a convex elevation, and providing a second component, which has a through-hole. The method also includes placing the two components one against the other such that the convex elevation of the first component protrudes into the through-hole in an interlocking manner, and welding the two components along the rim of the through-hole by way of a laser welding device. The welding is performed without the use of a welding filler and the laser welding device is repeatedly switched on and off in a pulsed manner during the welding of the two components along the rim of the through-hole. |
US10946480B2 |
Foil fusion additive manufacturing system and method
An additive manufacturing system includes a foil supply drum, a melting energy source, and a processor. The foil supply drum is configured to be rotated for dispensing a foil sheet over a substrate surface supported by a build element. The melting energy source is configured to direct at least one melting energy beam onto a non-melted region of the foil sheet located over the substrate surface. The processor is configured to execute computable readable program instructions based on a three-dimensional digital definition of the object, and control the melting energy beam to selectively melt at least some of the non-melted region into melted portions forming a material layer of the object onto the substrate surface while separating the melted portions from non-melted portions, and command rotation of the foil supply drum for dispensing the foil sheet during manufacturing of the object in correspondence with the digital definition. |
US10946475B2 |
Tool for ultrasonic bonding and apparatus for ultrasonic bonding
A bonding tool as the tool for ultrasonic bonding includes a plurality of protrusion portions in a protrusion region at a contact tip portion. The plurality of protrusion portions are equally spaced at a longitudinal direction interval in an X direction as the longitudinal direction of the protrusion region, and an X direction outermost protrusion portion positioned outermost in the X direction is disposed separately from a side edge of the protrusion region in the X direction by a longitudinal direction side edge distance. The plurality of protrusion portions are disposed so that a first disposition condition {0.349≤EX (the longitudinal direction side edge distance/DX (the longitudinal direction interval)≤0.510} is satisfied. |
US10946473B2 |
Additive manufacturing on 3-D components
A method of forming structure on a component includes: providing a component having a first surface; adhering powder to the first surface; and directing a beam from a directed energy source to fuse the powder in a pattern corresponding to a layer of the structure. |
US10946472B2 |
Spot welding system including tip dresser for polishing electrode
A spot welding system includes a spot welding gun, a robot, and a tip dresser that polishes a face of electrode. The tip dresser includes a blade that cuts the face of the electrode and a blade driving motor that rotates the blade. A dresser control section of a control device detects torque of the blade driving motor. When the torque of the blade driving motor exceeds a predetermined torque upper limit value, the dresser control section carries out speed reduction control that reduces the rotation speed of the blade driving motor. |
US10946470B2 |
Resistance spot welding method and welded member production method
Provided is a resistance spot welding method that inhibits, in accordance with the degree of axis misalignment between electrodes, the occurrence of cracking in a weld regardless of the steel grade. In resistance spot welding methods according to the present invention, H (ms) is an electrode force retaining time after completion of current passage, D (mm) is an amount of axis misalignment between the electrodes, t (mm) is a total sum of sheet thicknesses of a plurality of overlapping steel sheets, T (MPa) is a tensile strength of a steel sheet having a highest tensile strength among the plurality of steel sheets, F (N) is an electrode force, and d (mm) is a tip diameter of one electrode of the pair of electrodes that has a smaller tip diameter. The electrode force retaining time H is specified to be a predetermined value or greater. |
US10946467B2 |
Adapter mechanism and a related system for a welding apparatus
A system for a welding apparatus including a welding cup; a hollow tubular adapter body extending longitudinally from a first end to a second end, an external surface of the adapter body defining one or more grooves extending about a circumference thereof and longitudinally disposed between the first and second end; and one or more O-rings configured to be installed about the adapter body and received in each of the one or more grooves; wherein the first end or the second end of the adapter body is engageable with a welding torch head and wherein the welding cup is configured to receive the other of the first end and the second end of the adapter body therein, the welding cup extending longitudinally along the adapter body such that the one or more O-rings is disposed between the adapter body and the welding cup. |
US10946464B2 |
Slag removal system and method
A device to unclog orifices in a workpiece is provided. The device includes a lower portion configured to receive the workpiece and an upper portion configured to secure the workpiece to the lower portion. The upper portion includes a tube configured to receive a piston. An unclogging material is placed in the tube portion, and the piston forces the unclogging material through the orifices. |
US10946458B2 |
Cutting insert and drilling tool
A cutting insert for a drilling tool is disclosed includes an insert body having a longitudinal direction. A first axial side extends across the longitudinal direction on opposite sides of the insert body. The insert body has a first cutting edge extending along a rim portion at an intersection between a first rake face and the first axial side. The first axial side includes a first relief face and a second relief face. The first and second relief faces form obtuse angles with an imaginary centre plane of the insert body. |
US10946457B2 |
Pocket hole jig
A pocket hole jig includes a body with a base surface positionable against a workpiece, and a drill guide pivotally coupled to the body. The drill guide defines a guide axis such that a drill bit is insertable into the drill guide along the guide axis. The drill guide is pivotable relative to the body to adjust an inclination angle of the guide axis relative to the base surface. |
US10946455B2 |
Keyless chuck assembly
A keyless chuck for attaching a tool bit to a power tool includes a knob having a central aperture and defining a longitudinal axis, a hub within the central aperture and configured to attach to the power tool, and a collet within the hub and having a receiving end configured to receive the tool bit. The knob is adjustable between a locked position in which a clamping force is applied to the collet to retain the tool bit therein, and an unlocked position in which the clamping force is relieved to permit removal of the tool bit. |
US10946450B2 |
Machine tool
An automatic lathe includes a positioning block that positions a rod material, the rod material projecting from a main spindle contacting the positioning block, and a sensor that moves in a direction intersecting with a shaft center C direction of the main spindle to detect a cut off condition of the rod material. The positioning block includes a groove that allows movement of the sensor, and moves in the same direction as a movement direction of the sensor between a position that contacts the rod material and a position that has no contact with the rod material. The sensor moves along the path in the position that has no contact with the rod material. |
US10946449B2 |
Device and method for melting a material without a crucible and for atomizing the melted material in order to produce powder
The present disclosure relates to a device for melting a material without a crucible and for atomizing the melted material in order to produce powder, comprising: an atomizing nozzle; an induction coil having windings, which become narrower in the direction of the atomizing nozzle at least in some sections; and a material bar at least partially inserted into the induction coil. The induction coil is designed to melt the material of the material bar in order to produce a melt flow. The induction coil and the atomizing nozzle are arranged in such a way that the melt flow is or can be introduced into the atomizing nozzle through a first opening of the atomizing nozzle in order to atomize the melt flow by means of an atomizing gas, which can be introduced into the atomizing nozzle. |
US10946443B2 |
Removal of unfused powder from an additive-manufactured part using piezoelectric transducers
Removing unfused powder from internal passages of an additive-manufacture part includes attaching piezoelectric transducers to a plurality of locations on an exterior of the part. The part is vibrated by driving the piezoelectric transducers at varying amplitudes and frequencies. An amount of the unfused powder that exits the part is monitored. |
US10946440B2 |
Process and apparatus for minimizing the potential for explosions in the direct chill casting aluminum alloys
Steam exhaust ports are located around a perimeter of a direct chill casting pit, at various locations from below the top of the pit to the pit bottom to rapidly remove steam from the casting pit with addition of dry excess air. Gas introduction ports are also located around a perimeter of the casting pit and configured to introduce an inert gas into the casting pit interior. |
US10946438B2 |
Tubular shape casting apparatus
A system for casting a length of a pole of a tubular shape with molten metal. The system comprises a crucible for containing the molten metal; a pouring spout fluidly connected to the crucible; and a plunger for plunging in the crucible to increase level of the molten metal in the crucible and thereby forcing a flow of the molten metal from the crucible to the pouring spout. The system further comprises a casting ring for receiving the molten metal poured out of the pouring spout; a motor for rotating the casting ring; a cooling assembly for cooling the molten metal; and a pulling assembly for pulling the pole out of and away from the casting ring as the molten metal solidifies. |
US10946435B2 |
Green sand mold and its production method, and production method of iron-based casting
A green sand mold comprising at least one pair of green sand mold parts each comprising a recess and a mating surface, wherein a cured layer comprising a thermosetting resin as a main component is formed on the recess and mating surface of each green sand mold part, and wherein the cured layer has hardness of 40-98, a thickness of 0.5-6 mm, and gas permeability of 70-150, is produced by applying a curing material comprising the thermosetting resin as a main component and having viscosity of 1-100 mPa·S to the recess and mating surface of each green sand mold part, combining the green sand mold parts, and then heat-hardening the curing material. |
US10946431B2 |
Method for shear processing
The present invention provides a method for shear processing whereby a sheared surface having a small residual stress and excellent surface properties is formed and the service life of a punch is prolonged in a shear processing for shearing, by a shear line that crosses a weld zone, a workpiece with a large thickness of level difference of a weld zone and/or obtained by welding together a steel sheet having a strength of 1000 MPa or more and another steel sheet. The shearing for shear processing method according to the present invention is a method for shearing a workpiece having a weld zone using a punch and a die, the method characterized in that two protrusions are provided to a cutting edge of the punch, all or part of the weld zone of the workpiece is flanked from the two sides by the two protrusions, and the workpiece is sheared by a shear line that crosses the weld zone. |
US10946428B2 |
Spinning apparatus and spinning method
A spinning apparatus for decreasing by spinning a thickness of a portion of a tube material having a uniform thickness except at a first axial end portion is disclosed. The spinning apparatus includes a spindle-side chuck having a conical concavity and a mandrel. The mandrel has a mandrel-side chuck formed in a form of a conical convexity corresponding in configuration to the conical concavity of the spindle-side chuck and a cylindrical portion for supporting the tube material. The spinning apparatus further includes a spinning roll for decreasing the thickness of the tube material by pressing the spinning roll against the tube material when the tube material is supported by the cylindrical portion of the mandrel. |
US10946427B2 |
Blank, forming plate, press formed article manufacturing method, and press formed article
A blank that is a material for an elongated press formed article having a substantially hat shaped lateral cross-section profile including a top plate section, a ridge line section, a flange section, and vertical wall section, and configured with a first portion in which the top plate section has a fixed width, and a second portion including a curved portion in which the top plate section exhibits an L-shape in plan view due to the vertical wall section, the ridge line section, and the flange section curving along with the width of the top plate section gradually increasing. The blank has a shape of an opened-out shape of the press formed article, additionally with a first recess, a protrusion, and a second recess provided to an edge of an excess portion additionally provided at an edge of a location that will form the flange section configuring the curved portion. |
US10946414B2 |
Method for impregnation of a part made of plastic material
A method for core impregnation of a finished part made of plastic material with an additive, including: dissolving the additive in a liquid medium to form a solution; placing the plastic part at ambient pressure in a pressure enclosure; hermetically sealing the chamber; impregnating the plastic part with the solution by a fluid at supercritical or near supercritical conditions in the enclosure at a pressure between 3 MPa and 6 MPa, at a temperature between 25° C. and 65° C. for a duration between 1 minute and 15 minutes; releasing the pressure inside the enclosure so that the liquid medium diffuses outside the plastic part and to trap the additive inside the plastic part. |
US10946411B2 |
System and method for fluid dispense and coverage control
Techniques herein include systems and methods for dispensing liquids on a substrate with real-time coverage control and removal control. Techniques also encompass quality control of dispense systems. Systems and methods enable visual examination of liquids progressing on a surface of a substrate. This includes capturing and/or examining stroboscopic images of movement of a given liquid on a working surface of a substrate, and then generating feedback data for modifying a corresponding dispense. Dispenses can be modified by increasing/decreasing a dispense rate and increasing/decreasing a rotational velocity of a substrate. Feedback can be generated by automated and/or manual analysis of real time progression as well as post-process analysis of collections of images. |
US10946408B2 |
Methods for applying materials to interface areas and applicator comprising a surface interface guide forming a continuous ring-shaped flow channel
Provided are methods and systems for applying materials at interface areas formed by fasteners and parts. Specifically, a material is delivered to an interface area such that at least a portion of a fastener remains free from this material. The interface area may be sealed such that the material is contained within that area. As such, a controlled amount of the material is dispensed in a precise location. An applicator used for this process may include a housing and inner guide slidably disposed within this housing. The material may be delivered through an annular flow channel between the housing and inner guide. The inner guide may be sealed against and, in some embodiments, centered with respect to the fastener. The housing may be sealed with respect to the part and, in some embodiments, may be rotated with respect to the part to redistribute the material at the interface area. |
US10946403B2 |
Tacky netting for collecting dirt and paint overspray
A flexible sheet collects overspray and keeps spray booth environments clean, thereby reducing or eliminating dust and foreign matter from landing on wet painted surfaces which might otherwise result in a paint surface defect. The flexible sheet comprises a woven or non-woven mesh or net material having apertures or perforations that penetrate through the sheet. The sheet is impregnated with a tacky substance, such that paint overspray and dirt particles cling to the impregnated sheet. In the preferred embodiment, the tacky substance is a wax-based substance, more preferably a natural or synthetic beeswax-based substance. The material may be made from polymeric filaments of nylon or other natural or synthetic fibers, threads or strands. The flexible sheet of material may be provided in roll form for use. Method of making a tacky netting are also disclosed. The product is particularly useful in vehicle spray-booth applications. |
US10946402B2 |
Dispensing device for dispensing liquids or fluids in general
The present invention concerns a dispensing device (100) for dispensing a liquid or fluid held in a container (C). The device (100) comprises: an engagement portion (101) for mutually engaging the device (100) and the container; drawing and dispensing means (102) suited to draw the fluid or liquid from the container (C) and then dispense it; a hollow operating cap (103) for operating the drawing and dispensing means (102); a dispensing nozzle or spout (104) provided with a dispensing duct (105) fixed to the operating cap (103). The dispensing nozzle or spout (104) can be switched through a rotary movement between a first dispensing position and a second non-dispensing position. The operating cap (103) and the dispensing nozzle or spout (104) are shaped in such a way as to respectively define a first stop surface (107) and a second stop surface (108); in the dispensing position the first and the second stop surfaces (107, 108) are arranged against each other. |
US10946396B2 |
Showers
A shower includes a shower assembly and a control member. The shower assembly includes a main body having a side wall, an end wall, a plurality of outlet bores and an inlet bore, wherein the side wall and end wall are connected to each other to compose an accommodating space. The outlet bores and the inlet bore are positioned on the side wall of the main body, and communicate with each other through the accommodating space. The control member is positioned in the accommodating space of the shower assembly, and has a flow channel and a plurality of through holes. Each of the through holes communicates with each other through the flow channel, and is corresponding to the inlet bore or one of the outlet bores. When the control member is operated, at least one of the through holes communicates with the inlet bore, and another one of the through holes communicates with the corresponding one of the outlet bores. |
US10946395B2 |
Shower head
A shower head includes a spinning disk, which includes a fluid inlet, an upper plate coupled to the fluid inlet at the center of the upper plate, a lower plate coupled to the upper plate to form a perimeter edge of the spinning disk, at least two side spin ports on the perimeter edge, each side spin port is configured to project the fluid at a fluid projection angle relative to the perimeter edge and not perpendicular to the perimeter edge at such side spin port, and a plurality of fluid outlets on the lower plate configured to allow the fluid to flow out of the spinning disk, wherein the spinning disk is configured to spin when the fluid is projected from the at least two side pin ports while the fluid also flows out of the spinning disk from the fluid outlets. |
US10946391B2 |
Magnetic filter with drain and removable external magnetic element
A magnetic filter 10 for a central heating system is disclosed, the filter 10 including a connection assembly 12, a canister 14, and a magnetic element 16, the connection assembly 12 including an inlet 24 and an outlet 26 for connection to a central heating circuit; the canister 14 having an interior separation chamber which is fluidly connected with the inlet 24 and outlet 26 for allowing fluid to flow into the inlet 24, through the separation chamber, and out of the outlet 26; and the magnetic element 16 being removably positionable on the outside of the canister 14, the canister 14 and the connection assembly 12 forming a sealed flow path comprising the inlet 24, the interior separation chamber and the outlet 26, and the connection assembly 12 further including a closable drain outlet 28b for draining fluid and magnetic particles from within the canister 14, internally of the magnetic element 16. |
US10946379B2 |
Microfluidics system
Provided herein are a system and method for using a microfluidics device. The system includes: a plurality of pumps and a plurality of sensors; a first communication line to select a pump from the plurality of pumps and select a sensor from the plurality of sensors; a second communication line selectively connected to the selected pump; and a third communication line selectively connected to the selected sensor. |
US10946377B2 |
Modular instrumentation for analyzing biological fluids
A modular analytic system includes a base, at least one fluid sample processing module configured to be removably attached to the base, at least one fluid sample analysis module configured to be removably attached to the base, a fluid actuation module positioned on the base, a fluidic network comprising multiple fluidic channels, in which the fluid actuation module is arranged to control transport of a fluid sample between the at least one sample processing module and the at least one sample analysis module through the fluidic network, and an electronic processor, in which the electronic processor is configured to control operation of the fluid actuation module and receive measurement data from the at least one fluid sample analysis module. |
US10946372B2 |
Method for determining the position of a robotic arm in a liquid handling system, and a corresponding liquid handling system
The present invention relates to a method for determining the position of a robotic arm in an automatic liquid handling system in which a measurement probe with a first electrode is arranged on the robotic arm and, together with a second electrode formed by at least part of a working area or at least part of a container or container carrier forms a measurement capacitor that is operatively connected to a measurement unit for measuring an impedance, in particular a capacitance of the measurement capacitor. The method involves moving the measurement probe along a first path, detecting a first change in the impedance, in particular in the capacitance of the measurement capacitor at a first point on the first path, and defining at least one first reference spatial coordinate for a control unit of the robotic arm on the basis of the first point on the first path. |
US10946371B2 |
Methods of treatment and use of spent equilibrium catalyst
Disclosed is a method of treating spent equilibrium catalyst (ECAT) for reuse, in which a quantity of spent ECAT comprising hydrophilic particles with differing levels of metal contamination is disposed into a reactor and treated to form carbon nanotubes on the particles having metal contamination, thereby rendering at least a portion of the spent ECAT particles hydrophobic; the hydrophobic particles can then be separated from the hydrophilic particles. Also disclosed is a method of remediating an oil spill using a carbon nanotube sponge material. |
US10946367B2 |
Method of synthesis of nano-sized beta zeolites containing mesopores and uses thereof
A method for hydrocracking a hydrocarbon feedstock, the method comprising: contacting the hydrocarbon feedstock with a catalyst containing a nano-sized mesoporous zeolite composition under reaction conditions to produce a product stream containing at least 20 weight percent of hydrocarbons with 1-4 carbon atoms, wherein the nano-sized mesoporous zeolite composition is produced by a method that includes: mixing silica, a source of aluminum, and tetraethylammonium hydroxide to form an aluminosilicate fluid gel; drying the aluminosilicate fluid gel to form a dried gel mixture; subjecting the dried gel mixture to hydrothermal treatment to produce a zeolite precursor; adding cetyltrimethylammonium bromide (CTAB) to the zeolite precursor to form a templated mixture; subjecting the templated mixture to hydrothermal treatment to prepare a CTAB-templated zeolite; washing the CTAB-templated zeolite with distilled water; separating the CTAB-templated zeolite by centrifugation; and drying and calcining the CTAB-templated zeolites to produce a nano-sized mesoporous zeolite composition. |
US10946361B2 |
Compositions and methods for selectively sequestering metal ions
Compositions and methods for the selective sequestration of metal ions are generally described. |
US10946358B2 |
Skid-mounted depressurizing system
A skid-mounted depressurizing system includes a main process module, a mechanical control system, a thermodynamic balance system and an intelligent control system. The main process module includes multiple main process pipelines, each of the multiple main process pipelines is provided with a pressure reducing valve set. During depressurization, process medium enters at least one of the multiple main process pipelines, the mechanical control system outputs a torque according to the control instruction of the intelligent control system to control each valve of the multiple main process pipelines to perform an action switch and an opening degree adjustment, the thermodynamic balance system is configured to provide the medium of different properties to the multiple main process pipelines according to the control instruction of the intelligent control system to control temperature, pressure, cleanliness degree and/or sealing degree of the main process module. |
US10946356B2 |
Gas generator and method of generating a gas
A gas generator and a method of generating a gas are provided. A gas generator includes a cartridge having a solid reactant and a liquid reactant distributor provided therein, and a liquid reactant supply in fluid communication with the liquid reactant distributor. The liquid reactant supply is configured to provide a liquid reactant under pressure to the liquid reactant distributor. The liquid reactant distributor comprises a plurality of normally closed holes configured to open at a predetermined fluid pressure to disperse the liquid reactant for reaction with the solid reactant in the cartridge. |
US10946355B2 |
Device and method for dispersing at least one substance in a fluid
A device and a method for dispersing at least one substance in a fluid is disclosed. The device includes a process housing with a rotor, a fluid supply, a feed line for the at least one substance to be dispersed having at least one outlet opening, as well as a product outlet. The rotor brings about an axial delivery of a supplied fluid at least in some sections. Furthermore, the rotor brings about a radial delivery of the supplied fluid at least in some sections. |
US10946350B2 |
Mixing device for mixing a liquid plastics component with a gas
A mixing device for mixing a liquid plastics component with a gas, includes a liquid feed, a gas feed, and a discharge opening for discharging the mixture generated in the mixing device. Each of the liquid feed, gas feed, and discharge opening is connected to a mixing chamber in which a rotatable agitator device is arranged. A shaft for driving the agitator device projects out of the mixing chamber, and the mixing chamber is sealed off, in the region of the shaft, by a seal. On that side of the seal which is averted from the mixing chamber, there is a reservoir which is connected to the liquid feed and which is connected by a passage to the mixing chamber. |
US10946346B2 |
Sperm separation by electrophoresis
The present invention relates to the separation of sperm. In particular, the present invention relates to the use of polyvinyl alcohol membranes in the electrophoretic separation of sperm. |
US10946345B2 |
Microporous polyvinylidene fluoride membrane
Hydrophobic hollow-fiber membrane made from a vinylidene fluoride polymer with a wall and a wall thickness, an outer surface on its outer side, an inner surface on its inner side and facing its lumen and adjacent to the inner surface a supporting layer having a structure that is substantially isotropic across the wall thickness, the supporting layer extending over at least 80% of the wall thickness and comprising pores having an average diameter of less than 1 μm, and wherein the hollow-fiber membrane has pores on its outer surface and on its inner surface, characterized in that the vinylidene fluoride polymer has a weight-average molecular weight MW in the range from 550 000 to 700 000 daltons and a polydispersivity greater than 3.0; the pores in the outer and in the inner surface are formed like islands and have a maximum ratio of their longitudinal extension to the transverse extension of 10; the porosity lies in the range from 50 to 90 vol. %, the wall thickness in the range from 50 to 300 μm, and the diameter of the lumen in the range from 100 to 500 μm; and the hollow-fiber membrane has a maximum separating pore diameter dmax in the range from 0.3 to 0.7 μm, determined according to the bubble point method. |
US10946340B2 |
Superhydrophobic coated micro-porous carbon foam membrane and method for solar-thermal driven desalination
A solar membrane distillation apparatus includes a housing comprising a light transmitting wall. A solar distillation membrane is positioned in the housing to receive solar radiation transmitted through the light transmitting wall. The solar distillation membrane includes a porous graphitic foam and a coating of a hydrophobic composition on the surface and pores of the graphitic foam. A water chamber within the housing is provided for retaining water adjacent to the solar distillation membrane. A vapor chamber is provided for collecting water vapor distilling through the solar distillation membrane. A condenser is provided for condensing distilled water vapor from the vapor chamber into liquid water. A separation membrane and a method of solar distillation are also disclosed. |
US10946331B2 |
System and method for removing acid gas from a sour gas stream
Embodiments of methods and associate system for removing acid gas from a sour gas stream are provided. The method includes (1) passing the sour gas stream in a counter-flow arrangement with an encapsulated phase change material and a lean amine based sorbent liquid configured to absorb the acid gas from the sour gas stream in an absorber; (2) separating the rich amine based sorbent liquid and the encapsulated phase change material; (3) passing the rich amine based sorbent liquid to an amine regenerator wherein the rich amine based sorbent liquid is heated to release the absorbed sour gas and regenerate the lean amine based sorbent liquid; and (4) passing the encapsulated phase change material and the regenerated lean amine based sorbent liquid through a cooler to reduce the temperature of the encapsulated phase change material such that the phase change material in the encapsulated phase change material solidifies. |
US10946330B2 |
System and method for removing acid gas from a sour gas stream
Embodiments of methods and associate system for removing acid gas from a sour gas stream are provided. The method includes (1) passing the sour gas stream in a counter-flow arrangement with an encapsulated phase change material and a lean amine based sorbent liquid configured to absorb the acid gas from the sour gas stream in an absorber; (2) separating the rich amine based sorbent liquid and the encapsulated phase change material; (3) passing the rich amine based sorbent liquid to an amine regenerator wherein the rich amine based sorbent liquid is heated to release the absorbed sour gas and regenerate the lean amine based sorbent liquid; and (4) passing the encapsulated phase change material and the regenerated lean amine based sorbent liquid through a cooler to reduce the temperature of the encapsulated phase change material such that the phase change material in the encapsulated phase change material solidifies. |
US10946329B2 |
System and methods for separating and purifying cannabinoids from plant material
Methods and systems are disclosed for concentrating a compound found in plant material from one or more species of the Cannabis genus. A system includes a capture/heating station having at least one heating element to heat a mass of material held within the capture/heating station; at least one release station in series with and liquidly isolated from the capture/heating station, each release station defining a volume at least partially filed by a release reagent formulated to release a target product from a substrate; and a conveyor configured to carry a belt through the capture/heating station and then the at least one release station. |
US10946327B2 |
Use of a peak-dampening capacitor to improve adsorber separation performance
This invention uses a fixed-bed adsorber, interchangeably called a capacitor herein, to process the product stream coming out of a regenerable adsorption system such as a temperature swing adsorption system (TSA) or pressure swing adsorption system (PSA). The fluid stream coming out of this fixed-bed capacitor will have a more uniform composition than the one entering the adsorption system or the capacitor. The fixed-bed adsorber operates in a once-through non-cyclic manner, similar to a conventional fixed bed reactor or adsorber. |
US10946325B2 |
Filter component
There is a need to reduce the amount of overlapping parts of a nonwoven fabric of a filter component to thereby lengthen the life of the filter component. This need is met by the filter component formed of a cylindrical nonwoven fabric having a center axis, and having a plurality of polygon-shaped cross-sections which are a same shape that are formed side-by-side at predetermined intervals along the center axis. Each side of each of the polygons is formed by a mountain fold part on a plane perpendicular to the center axis, and each vertex of one polygon is connected by a mountain fold part to each vertex of another polygon, respectively. |
US10946323B2 |
Round filter element, in particular for gas filtration
A round filter element has a filter medium body with a wall to be flowed through by a fluid to be purified in a radial direction relative to a longitudinal axis of the filter medium body. A circumferentially extending seal carrier is arranged at or adjacent to an end face of the filter medium body. A sealing element is supported at the seal carrier adjacent to a radial outer side of the filter medium body. A positioning element extends into the filter medium body and engages with form fit a correlated housing-associated counter positioning element of a filter housing when the round filter element is installed in the filter housing. The seal carrier separates flow-tightly a raw side of the round filter element from a clean side of the round filter element when the round filter element is installed in the filter housing. |
US10946321B1 |
UV enabled fins encapsulation system
A general-purpose air sterilizing system destroys activation of air-borne pathogens, designed with different embodiments. The methods used to build the apparatus allows destroying airborne pathogens like bacteria, mold, mildew, allergens and deactivates viruses such as SARS CoV-2. The apparatus supports air circulation system that contains filter which comprising array of Ultraviolet (UV) Light Emitting Diode (LEDs) of 262-nm wavelength, AKA UVC, are used. |
US10946318B2 |
Filter panel with structures support grid and drum filter with said filter panel
The invention relates to a filter panel (1) for a drum filter (2) which is used for filtering off solid particles from a liquid. The filter panel (1) comprises a first side (3) being adapted to be attached to a drum (4) of said drum filter (2), a second side (5) being adapted to receive a filter cloth (6), and a plurality of through holes (7) extending from said first side (3) to said second side (5), each hole (7) defining one or more side walls (8). The filter panel (1) is characterized in that at least one of said holes (7) comprises an inclined side wall (8). The invention also relates to a drum filter (2) for filtering liquid. |
US10946316B2 |
Filter cartridge having double water-stop function
A filter cartridge having a double water-stop function, that comprises: a filter cartridge main body, a rotation body, and a water channel main body. The filter cartridge main body includes: an outer shell body, a filter cartridge, a filter cartridge cover, a first water outlet, a second water outlet, a first compression spring, a second compression spring, a first tight seal ring, a second tight seal ring, a first water input port, a second water input port, a first water outlet channel, and a second water outlet channel. The rotation body includes: a first water channel, a second water channel, a third water channel. The water channel main body includes: a first water input hole, a first water output hole, and a second water output hole. |
US10946308B2 |
Enzymatic method for extraction and purification of phytocannabinoids
An example method of extracting phytocannabinoids from plants includes obtaining plant parts from at least one plant, the at least one plant including one or more of Cannabis, Turmeric, Ginseng, Ginkgo, Ginger, Vinca, and Bacopa. The plant parts are cooled, and are incubated in an incubation mixture of cellulose, pectinase, amylase, and proteinase dissolved in a buffer. The incubation mixture is evaporated in an evaporation chamber to obtain a phytocannabinoid extract. |
US10946301B2 |
Compact wastewater concentrator using waste heat
A compact and portable liquid concentrator includes a gas inlet, a gas exit and a flow corridor connecting the gas inlet and the gas exit, wherein the flow corridor includes a narrowed portion that accelerates the gas through the flow corridor. A liquid inlet injects liquid into the gas stream at a point prior to the narrowed portion so that the gas-liquid mixture is thoroughly mixed within the flow corridor, causing a portion of the liquid to be evaporated. A demister or fluid scrubber downstream of the narrowed portion removes entrained liquid droplets from the gas stream and re-circulates the removed liquid to the liquid inlet through a re-circulating circuit. Fresh liquid to be concentrated is also introduced into the re-circulating circuit at a rate sufficient to offset the amount of liquid evaporated in the flow corridor. |
US10946299B1 |
Illuminated multi-color spinner assembly
An illuminated spinner having a handle, a motor within the handle controlled by a switch on the handle, a shaft extending from the handle, and a spinning object on which a lighting element is mounted, is provided with a decorative shell that encloses the object and is mounted on the handle, and that is constructed of at least three translucent pieces, as least two of which have different color transmitting or abo properties. The at least one light source is visible through the shell over an angle of 360® when the object is spinning and the light source is illuminated. |
US10946296B1 |
Scissor lift construction equipment amusement ride
An amusement ride providing the sensation of riding scissor lift construction equipment to ride passengers is disclosed. The amusement ride has a scissor lift mechanism supported by a construction equipment frame with wheels thereon. A stationary support structure supports the equipment frame and suspends the wheels in midair to hold the equipment stationary. A cargo lift platform connected on top of the scissor lift mechanism has amusement ride seats mounted thereon. The ride seats have passenger restraints which provides amusement-ride-level safety. An electric motor drivingly connected to the scissor lift mechanism is operated by a ride operator to raise and lower the cargo lift platform. A passenger access platform situated adjacent the cargo lift platform allows ride passengers to easily and safely enter and exit the scissor lift. |
US10946295B2 |
Amusement ride with controllable helical motion of an eccentric rider around the central axis of the route of the rider
An amusement ride enabling at least one rider to change a position of said at least one rider around at least one cylindrical vehicle while said at least one cylindrical vehicle carries said at least one rider along a central axis of said at least one cylindrical vehicle during a riding. |
US10946292B1 |
Non-player game navigation
A system in which players participate as characters in a virtual game world via game clients executing on client devices. An observer mode is provided that enables users to navigate in the game world without requiring a game client so that a user can navigate the game world while not actively playing the game. When a user accesses the game in observer mode, a view of the game world is rendered from the viewpoint of an observer's character; the observer's character may not correspond to a character in the game and the observer's character may not be visible to the players in the game. The rendered view of the game world is streamed to a viewing application on a personal device. Navigation inputs allow the observer's character to move freely within the game world. |
US10946289B2 |
Storage medium, game system, game apparatus and game controlling method
A non-limiting example game system comprises a processor incorporated in a main body apparatus, and the processor displays, in a battle scene, a battle screen including a player character, an enemy character and a board face object on a display. The board face object having a circular board face that is formed with multiple partial objects that are sectioned by multiple concentric circles and multiple lines extended radially. A player makes the multiple partial objects move in a circumferential direction or a radial direction so as to change arrangement of multiple enemy characters placed on the multiple partial objects, thereby causing the player character to perform an attack. |
US10946286B2 |
Game system, game processing method, information processing apparatus, and storage medium having stored therein information processing program
A non-limiting example game system includes a plurality of terminal apparatuses operated by a plurality of players, and connect to a network. The computer system creates a virtual lobby that allows up to a predetermined number of players to participate therein, and sets a player who operates one of the terminal apparatuses as a player who is virtually present in the lobby in response to a request from that terminal apparatus. The game system also automatically selects one from a plurality of games including at least games requiring different numbers of participant players, according to the number of players who are present in the lobby and are not playing a game and are ready to play, and automatically selects participant players in the selected game from the players ready to play. |
US10946282B2 |
Control object spatial location determining method and apparatus
The present disclosure discloses a control-object spatial-location determining method and apparatus. The method includes: detecting, by a game engine of the game application, a spatial-location request, wherein the game engine is not applying physical collision, and the spatial-location request is a request for determining, based on a first spatial-location of a first control-object in the game application, a second spatial-location of a second control-object; determining, by the game engine, multiple candidate spatial-locations according to the first spatial-location of the first control-object, wherein the multiple candidate spatial-locations surround the first spatial-location, and any two of the multiple candidate spatial-locations and the first spatial-location do not overlap; and determining, by the game engine, an unoccupied candidate spatial-location among the multiple candidate spatial-locations as the second spatial-location of the second control-object. |
US10946279B1 |
Context-based notifications on a user display
Techniques for managing notifications are described. In an example, a computing device presents content in an application window based on an execution of an application. Notification data is received by a computing device. Based on a context associated with the computing device, such as whether the application window is the foreground and whether the notification data is associated with the application or such as the operational mode of the computing device, a determination is made whether to present a corresponding notification in-context within the application window or in a pop-up window. Otherwise, the notification is added to a notification list and can be summarized in a notification summary. |
US10946276B2 |
Application state backup and restoration across multiple devices
Some examples of application state synchronization may include receiving, at a server, application state data from an electronic device. For instance, the application state data may represent an application state of a computer application running at the electronic device when a backup event occurs. An analysis may be performed based on at least one of a user profile or a usage pattern. A set of electronic devices may be identified based on the analysis. Further, the application state data may be transmitted to the set of electronic devices. |
US10946270B2 |
System and method for offline configuring of a gaming accessory
A peripheral device is configured to obtain configuration information from user equipment. The configuration information is for the peripheral device, wherein during receipt of the configuration information the peripheral device is not in communication with the user equipment. The configuration information is based on selections obtained via the user equipment and associated with operational parameters for the peripheral device. The configuration information is stored in a memory that is remote from the user equipment. Provisioning information is provided to the user equipment, wherein the provisioning information is associated with the configuration information and wherein the provisioning information enables configuration of the peripheral device with the operational parameters. |
US10946263B2 |
Apparatus and method for optimizing a person's muscle group performance thru modulating active muscle groups exertion rate and oxygen quantum
A system and method for optimizing a person's muscle group performance thru modulating the arm, leg, and core muscle exertion rate based upon the exerciser's metabolic and geographic data. The system uses real-time measurement gathering and storing of physiologic parameters from humans during physical exercise activity and the geographic data of the exercise activity to determine information for optimizing the exerciser's physical exercise performance of the basic working muscle groups in the rider's arms, legs, and core. The system broadcasts to exercisers information including, but are not limited to: a) the current condition of their monitored muscle tissue, b) which muscle groups the riders should modulate and change their level of energy output during the exercise activity, and c) level of energy exertion at which riders should be employing at that moment in the relevant working muscle groups to optimize their physical exercise performance. |
US10946260B1 |
Sporting apparatus training aid
A sporting apparatus training aid having a central wall with an inner surface, an outer surface opposing the inner surface of the cylindrical central wall, and with one or more plate-like side fin(s) radially extending outwardly from the outer surface of the central wall, the training aid also having a plate-like base fin coupled to the side fin(s) at an angle to create air resistance thereon and in multiple directions when a sporting apparatus and the training aid are swung together. |
US10946259B1 |
Adjustable grip
Provided is an adjustable putter grip. The adjustable putter grip includes a first grip member coupled adjacent a first end of a putter shaft. A putter head is coupled to a second end of the putter shaft. The adjustable putter grip also includes a second grip member coupled to the putter shaft between the first grip member and the second end of the putter shaft. The first grip member and the second grip member are rotatable with respect to each other to adjust grip position, the second grip member is rotatable with respect to the first grip member to adjust grip position, or the first grip member is rotatable with respect to the second grip member to adjust grip position. A method of forming a custom grip or custom fitting of a golfer is also disclosed. |
US10946258B1 |
Adjustable grip
Provided is an adjustable putter grip. The adjustable putter grip includes a first grip member coupled adjacent a first end of a putter shaft. A putter head is coupled to a second end of the putter shaft. The adjustable putter grip also includes a second grip member coupled to the putter shaft between the first grip member and the second end of the putter shaft. The first grip member and the second grip member are rotatable with respect to each other to adjust grip position, the second grip member is rotatable with respect to the first grip member to adjust grip position, or the first grip member is rotatable with respect to the second grip member to adjust grip position. A method of forming a custom grip or custom fitting of a golfer is also disclosed. |
US10946257B1 |
Golf accessory for determining gimme putt
A golf accessory for determining a gimme putt distance is disclosed. The golf accessory comprises a handle with a trigger, a telescoping rod mounted to the trigger including a length adjustment configuration, a hinge mechanism mounted to the telescoping rod and a base mounted to the hinge mechanism. The hinge mechanism is configured to allow the telescoping rod to fall horizontally on a ground surface upon activation of the trigger to determine a gimme distance in a golf game. The gimme is determined as positive if the telescoping rod covers a ball marker on the ground surface. The gimme is determined as negative if the telescoping rod fails to cover a ball marker on the ground surface. |
US10946255B2 |
Methods of manufacturing golf club heads
A golf club head comprising at least one part manufactured via a metal injection molding process, and attached to another part of the golf club head via electrical resistance welding or electrical resistance brazing, is disclosed herein. The present invention is also directed to a method of making said golf club head, the method comprising the steps of providing a first golf club head part made from a first metal material, metal injection molding a second golf club head part from a second, different metal material, and electrical resistance welding or electrical resistance brazing the second golf club head part to the first golf club head part to form a combined part. |
US10946254B1 |
Golf club head and method for manufacturing the same
A method includes: providing a mold assembly includes lower and upper molds; placing a release film on the lower mold and vacuuming a lower cavity of the lower mold; attaching a first molding member to the release film, and moving the release film and the first molding member into an upper cavity of the upper mold; placing a transfer film on the lower mold and vacuuming the lower cavity; attaching a second molding member to the transfer film; hot molding the first and second molding member into a golf club head part having a patterned surface formed by a transfer surface of the transfer film; and connecting the golf club head part to a golf head shell to obtain a golf club head. |
US10946251B2 |
Multi-piece solid golf ball
In a multi-piece solid golf ball having a core, a cover and an intermediate layer therebetween, the core, an intermediate layer-encased sphere and the ball have surface hardnesses which satisfy a specific relationship, and the intermediate layer and the cover have thicknesses which satisfy a specific relationship. Also, the core has a hardness profile in which the hardnesses at the core surface, core center, a position 5 mm from the core center, and a position midway between the surface and center of the core satisfy specific relationships. This golf ball, when used by mid- and high-level amateurs, enables the golfer to maintain an adequate distance on shots with a driver and achieve a good distance on iron shots, has a good spin performance on approach shots and has a good feel on impact. In addition, the ball has an excellent scuff resistance when struck with a grooved wedge. |
US10946247B1 |
Unstable surface training apparatus and method of use thereof
The present disclosure relates, in one embodiment, to an unstable surface training apparatus. The apparatus may include a platform that is pivotally connected to a support member about the pivot axis. The apparatus may include at least one user handle that is adjustably connected to the platform. The platform may be freely pivotable about the pivot axis up to a maximum degree of rotation. Some embodiments of the exercise apparatus may include an base upon which the support member is connected. The base provides the exercise apparatus with increased stability. Other embodiments of the exercise apparatus may include a rotational restriction assembly disposed between the support member and the platform for limiting the maximum degree of rotation. |
US10946240B2 |
Glute machine
A weight resistance training machine is provided that is used to exercise the glute muscles of a user. The weight resistance training machine includes a carriage member that a user may mount to use the training machine. The carriage member may be mounted on a track system that allows the carriage member to translate linearly when the weight training machine is used. When a foot press bar connected to the carriage member is extended, the carriage member is linear translated by a cable and pulley system to increase the muscle path length during exercise and increase the exercise's efficacy. |
US10946238B1 |
Exercise machines having adjustable elliptical striding motion
An exercise machine is for performing a striding exercise motion. The exercise machine has frame; first and second pedal members; first and second foot pads on the first and second pedal members, respectively, each of the first and second foot pads being configured to move in an elliptical path during the striding exercise motion; first and second rocker arms pivotally coupled to the frame; and first and second adjustment devices configured to actively adjust and set a position of the first and second pedal members relative to the first and second rocker arms, respectively, which thereby changes a shape of the elliptical path. |
US10946236B2 |
Omnidirectional treadmill
Disclosed is an omnidirectional treadmill which has several connected belt units with supporting frames and endless belts which are moved revolving in the first spatial direction. In the second spatial direction, the endless belts of the belt units are moved. The endless belts are driven in the second spatial direction preferably by gear wheels mounted on rolls and by a toothed shaft. The movement of all endless belts is synchronized by coupling with special tooth form crown gears arranged between the belt units. |
US10946234B2 |
Hand grip for transmitting stress through a hand strap to a wrist strap
A hand grip for transmitting tensile stress through a hand strap from an object, such as the bar of a barbell, being gripped to the wrist of the wearer without stressing the hand of the wearer, and extending around the bar of the barbell between the bar and the palm of the wearer. A block of relatively firm material is secured to and projects from the hand grip in a position to be engaged by the fingers of the wearer to lessen the possibility of the hand grip opening to release the bar of the barbell. The block has a flat front and a outer surfaces forming an edge for engagement under the knuckle of at least one finger of the hand of the wearer, and the front surface projects from the hand strap sufficiently to avoid lessening the grasp of the block by the fingers of the wearer. |
US10946231B2 |
Exercise device
Disclosed is an exercise device including flexible suspension unit, a mass, a fastening element and optionally a separate grip, wherein: a) the flexible suspension unit, elongated and thin in shape, are connectable at the level of at least a first end to the fastening element and at the level of an opposite end to one of such components; b) the mass has a through hole through which the suspension unit passes, the through hole being provided with a first opening and a second opening; and c) the fastening element can be blocked on the body of the mass. |
US10946228B2 |
Fire-extinguishing liquid agent and fire-extinguishing equipment loaded with said fire-extinguishing liquid agent
[Problem] To provide a fire-extinguishing liquid agent in which a fire-extinguishing agent is contained in a desirable balance and is satisfactorily dissolved in a solvent, that is easy to use, and that can be used against normal fires and oil fires, as well as fire-extinguishing equipment loaded with said fire-extinguishing liquid agent. [Solution] A fire-extinguishing liquid agent is sealed in an impact breakable container B that is molded by using a polystyrene resin material in which a general-purpose polystyrene and a styrene-butadiene copolymer are mixed and that has a hand-throwable size, wherein the fire-extinguishing liquid agent is formed: by containing 68-76 parts of sodium bicarbonate (NaHCO3) relative to 100 parts by weight of ammonium chloride (NH4Cl); by being treated by passing through a magnetic field having a magnetic flux density of 3000-10000 G; by being dissolved in hot water (magnetic water) in which the temperature thereof is adjusted to 30-50° C.; and by being adjusted to have a pH in a range of 7.5-10. |
US10946226B2 |
Stream straightener
A nozzle assembly includes a nozzle body and a flow straightener. The nozzle body defines an inlet configured to be fluidly coupled to fluid source, an outlet, and a nozzle body passage extending between the inlet and the outlet. The flow straightener is coupled to the nozzle body and extends at least partially across the nozzle body passage. The flow straightener defines a primary passage and a secondary passage extending through the flow straightener to fluidly couple the inlet and the outlet of the nozzle body. The primary passage defines a primary passage outlet having a cross-sectional area, and the secondary passage defines a secondary passage outlet having a cross-sectional area that is less than the cross-sectional area of the at least one primary passage. At least one of the primary passage outlet and the secondary passage outlet has a circular cross-section. |
US10946223B2 |
Facemask nosecup retained by voicemitters
A method and system for personal protective equipment, such as a respirator mask, having a nosecup that is removably coupled to the item of personal protective equipment by at least one of an electronics housing and at least one voicemitter. A respirator mask includes a frame including a voicemitter aperture, a voicemitter, and a nosecup removably coupled to the frame by a rotation of the voicemitter by a predetermined amount to removably lock the nosecup to the frame voicemitter aperture. The mask further includes electronics components, which are housed in an annular electronics housing located within the front portion of the mask body 14 and in contact with a front portion of the nosecup. The nosecup may further be removably coupled to the mask frame by coupling between the annular electronics housing and the mask frame. |
US10946221B2 |
Method for treating hair, kit, and use of the kit
A method, a kit and a first composition for treating hair are provided. The method for treating hair comprises applying to the hair a first composition comprising in a cosmetically acceptable carrier, one or more at least bi-functional carboxylic acids, or cosmetically acceptable salts thereof, or mixtures thereof, and applying to the hair a second composition comprising in a cosmetically acceptable carrier, one or more at least bi-functional carboxylic acids, or cosmetically acceptable salts thereof, or mixtures thereof, wherein the first composition has a pH from 7 to 13 and the second composition has a pH from 3 to 7. |
US10946220B2 |
Method of providing rotational radiation therapy using particles
Techniques are described herein for delivering a particle beam composed of a plurality of beamlets from a continuously rotating gantry towards a target, by determining a plurality of predefined spots on the target and configuring them into a set of smaller spots on the outside of the target and a set of larger spots on the inside of the target, optimizing the delivery of the rotating particle beam such that the inside edge and the outside edge of the arc of the rotating beam are delivered to the spots located at the center of the target, and the central component of the arc of the beam is delivered to the spots located at the outside of the target. |
US10946218B2 |
Magnetic resonance guided therapy with interleaved scanning
A method for controlling a medical apparatus (100) includes receiving a treatment plan (168) specifying a target volume (146) within an imaging volume (138) and a dose rate of radiation emitted by a radiotherapy apparatus (102). The medical apparatus (100) repeatedly acquires the motion tracking magnetic resonance data and the image magnetic resonance data using an interleaved pulse sequence. The radiotherapy apparatus (102) is controlled to radiate the target volume (146) in accordance with the treatment plan (168). A dose distribution map descriptive of a radiation dose received by the subject (144) from the radiotherapy apparatus (102) is calculated using the motion tracking magnetic resonance data, and the treatment plan (168). A diagnostic image is reconstructed using the image magnetic resonance data. A display displays the diagnostic image and the dose distribution map. Treatment plan update data is received from a user interface and the treatment plan (168) is updated in accordance with the treatment plan update data. |
US10946214B2 |
Automated anatomy delineation for image guided therapy planning
When delineating anatomical structures in a medical image of a patient for radiotherapy planning, a processor (18) detects landmarks (24) in a low-resolution image (e.g., MRI or low-dose CT) and maps the detected landmarks to reference landmarks (28) in a reference contour of the anatomical structure. The mapped landmarks facilitate adjusting the reference contour to fit the anatomical structure. The adjusted reference contour data is transformed and applied to a second image using a thin-plate spline, and the adjusted high-resolution image is used for radiotherapy planning. |
US10946213B2 |
Infrared radiation device
The present invention relates to an infrared radiation device including a mounting (2) capable of receiving a user (9) and a covering portion (1) capable of covering the user (9), the covering portion (1) including at least one heating layer (5a, 5b, 5c) capable of emitting infrared radiation (6) in a predetermined range of wavelengths towards at least one portion of the space located between the inner surface of the beating layer (5a, 5b, 5c) and the mounting (2), the device being characterised in that said heating layer (5a, 5h, 5c) is adjusted by at least one controller (10) including power-supply means (16) supplying the power necessary for infrared emission and at least one programmer (15) determining the parameters of a radiation session, by defining pulsations that control at least one synchronous static relay (14) which supplies said heating layer (5a, 5b, 5c) with the power provided by the power-supply means (16) during the pulsations. |
US10946209B2 |
Tubular, portable automated external defibrillator
Several defibrillators, defibrillator architectures, defibrillator components and methods of operating defibrillators are described. In one aspect, a defibrillator (as for example an automated external defibrillator) that can be powered by a mobile communication device such as a smart cellular phone or a tablet computer is described. Utilizing a phone (or other mobile communication device) as the power supply for an external defibrillator allows the external defibrillator to be smaller and, in some circumstance, removes the need for a battery that stores sufficient energy for shock delivery—which would need to be checked and/or replaced on a regular basis. Additionally, when desired, certain control functionality, computation, data processing, and user instructions can be handled/presented by the mobile communications device thereby further simplifying the defibrillator design and improving the user experience. This architecture takes advantage of the nearly ubiquitous availability of smart phones, tablet computers and other mobile communication devices. |
US10946206B2 |
Medical device recharging based on patient activity
Devices, systems, and techniques for controlling charging power transmitted to an implantable medical device during a recharging process based on patient activity are disclosed. Various example techniques include a method comprising receiving, by processing circuitry, an activity signal generated by an implantable medical device and indicative of an activity level of a patient during charging of a rechargeable power source of the implantable medical device implanted in the patient, determining, by the processing circuitry and based on the activity signal, a patient status for the patient during charging of the rechargeable power source, and controlling, by the processing circuitry and based on the patient status, charging of the rechargeable power source of the implantable medical device. |
US10946203B2 |
Leadless cardiac stimulation device employing distributed logic
Systems and methods involve an intrathoracic cardiac stimulation device operable to provide autonomous cardiac sensing and energy delivery. The cardiac stimulation device includes a housing configured for intrathoracic placement relative to a patient's heart. A fixation arrangement of the housing is configured to affix the housing at an implant location within cardiac tissue or cardiac vasculature. An electrode arrangement supported by the housing is configured to sense cardiac activity and deliver stimulation energy to the cardiac tissue or cardiac vasculature. Energy delivery circuitry in the housing is coupled to the electrode arrangement. Detection circuitry is provided in the housing and coupled to the electrode arrangement. Communications circuitry may optionally be supported by the housing. A controller in the housing coordinates delivery of energy to the cardiac tissue or cardiac vasculature in accordance with an energy delivery protocol appropriate for the implant location. |
US10946200B2 |
Plug-in accessory for configuring a mobile device into an external controller for an implantable medical device
Disclosed is a plug-in accessory for operating a mobile device as an external controller for an Implantable Medical Device (IMD). The accessory includes a connector insertable into a port on the mobile device. Accessory circuitry can be powered by a battery or by the mobile device. An application on the mobile device in conjunction with the accessory configures the mobile phone for immediate use as an IMD external controller. When the accessory is inserted into the port or a switch on the accessory pressed, the application operates to validate the accessory; to unlock the phone; to secure the mobile device; and to render a graphical user interface on the mobile device for communicating with the IMD. The accessory can additionally include telemetry circuitry and an antenna for communicating with the IMD, rather than using short-range communication means provided in the mobile device itself. |
US10946193B2 |
Pulse generator with independent panel triggering
A pulse generation system is disclosed. The pulse generation system includes a controller, an output terminal, and a plurality of pulse generator circuits. The controller is configured to cause a driving signal pulse to be transmitted to any selected one or more of the pulse generator circuits, and to cause the driving signal pulse to not be transmitted to any selected one or more other pulse generator circuits. Each of the pulse generator circuits is configured to generate an output voltage pulse at the output terminal in response to the driving signal pulse being transmitted thereto. |
US10946188B2 |
Systems and methods for treatment of an oral cavity
A method and apparatus for the concurrent treatment of multiple oral diseases and defects while promoting general oral hygiene utilizing direct current electricity and methods for manufacturing the same. Electrodes are used to deliver a direct current to the gingival tissues of a mouth in order to achieve a number of therapeutic, prophylactic, and regenerative benefits. These benefits include killing oral microbes, increasing oral vasodilation, reducing oral biofilm, improving oral blood circulation, reversing oral bone resorption, promoting oral osteogenesis, treating gum recession, and fostering gingival regeneration. Other benefits include the treatment of gingivitis, periodontitis, and oral malodor, and other systemic diseases correlated with oral pathogens. |
US10946187B2 |
Three-dimensional neural probe microelectrode array and method of manufacture
A three-dimensional neural probe electrode array system is described. Planar probes are microfabricated and electrically connected to flexible micro-machined ribbon cables using a rivet bonding technique. The distal end of each cable is connected to a probe with the proximal end of the cable being customized for connection to a printed circuit board. Final assembly consists of combining multiple such assemblies into a single structure. Each of the two-dimensional neural probe arrays is positioned into a micro-machined platform that provides mechanical support and alignment for each array. Lastly, a micro-machined cap is placed on top of each neural electrode probe and cable assembly to protect them from damage during shipping and subsequent use. The cap provides a relatively planar surface for attachment of a computer controlled inserter for precise insertion into the tissue. |
US10946182B2 |
Subcutaneous vein access port and medicine injection device having the same
A subcutaneous vein access port implanted into a living body to be connected to a subcutaneous vein, includes: a housing formed therein with a receiving portion to which a medicine is supplied; a cover membrane disposed at an upper end of the housing and sealing an upper side of the receiving portion; a conduit provided to the housing and inserted into the subcutaneous vein to connect the subcutaneous vein to the receiving portion; and a light source emitting light such that the light from the light source is discharged outside through the cover membrane. |
US10946181B2 |
Transdermal administration device
A plurality of projections in a transdermal administration device each include a columnar portion extending from a first surface of a substrate, and a tapered portion extending from a top of the columnar portion. A maximum angle of an apex of the tapered portion viewed in a direction parallel with the first surface is in a range of 10° or more and 30° or less, a ratio of a length from a proximal end to a distal end of the tapered portion to a length from a proximal end to a distal end of the projection as viewed in a direction perpendicular to the first surface is in a range of 0.45 or more and 0.75 or less, and a pitch (distance between centers of closest projections), viewed in a direction perpendicular to the first surface is in a range of 50 μm or more and 350 μm or less. |
US10946178B1 |
Method for preventing contrast induced nephropathy
The invention relates to a method to prevent contrast-induced nephropathy during an imaging procedure. The method includes the step of positioning balloon catheters in a patient's renal arteries and inflating the balloons of each catheter to block the flow of contrast media into the patient's kidneys. |
US10946176B2 |
Intravenous catheter assembly with safety clip
A catheter assembly may include a catheter, catheter adapter, needle, needle guard, and housing. The housing may be coupled to the needle guard and disposed within a lumen of the catheter adapter. The needle guard may include first and second resilient arms, which may include first and second curved portions, respectively. When the needle is in a ready position, the first and second curved portions may be urged by a shaft of the needle into retaining contact with an inner wall of the catheter adapter. When the needle is in the retracted position, the shaft may no longer bias the first and second resilient arms outwardly such that the retaining contact between the first and second curved portions and the catheter adapter is released, and the housing and the needle guard enclose a distal tip of the needle. |
US10946171B2 |
Catheter devices and methods for making them
Catheters, sheaths, or other tubular devices are provided that include a proximal end, a distal end sized for introduction into a patient's body, and a steerable distal portion. The tubular device includes a primary lumen extending between the proximal and distal ends; an auxiliary lumen adjacent the primary lumen; and one or more reinforcement members including windings extending helically along at least the distal portion, at least some of the windings passing between the primary and steering element lumens and at least some of the windings surrounding both the primary and steering element lumens. In one embodiment, a steering element is slidably disposed within the auxiliary lumen. Apparatus and methods for making such tubular devices are also provided. |
US10946162B2 |
System and method for on-demand near-patient humidification
A near-patient humidification system provides vapor to a respiratory breathing circuit. The system includes an expiratory gas conduit and an inspiratory gas conduit. A patient coupling member is provided for coupling the expiratory and inspiratory gas conduits to a patient interface. A vapor injection unit is located at least partially within the housing of the patient coupling member. The vapor injection unit heats a supply of fluid into vapor and injects the vapor into the inspiratory gas passage of the patient coupling member at a vapor injection location for providing moisture to the inspiratory gas flow. A method of simultaneously and independently controlling the temperature and humidity of inspiratory gas in a respiratory breathing circuit is performed by injecting vapor having a temperature determined as a function of measured temperatures and measured humidities of the breathing gas at different locations along the breathing circuit. |
US10946161B2 |
Pulsed pressure swing adsorption system and method
A pressure swing adsorption (PSA) system and methods for controlling each PSA cycle performed by the PSA system to produce oxygen enriched gas during productive portions of a user breathing cycle, and to cease production of oxygen enriched gas during non-productive portions of the user breathing cycle, is provided. The PSA system synchronizes PSA cycle phases including adsorption and desorption phases with a user's individual inhalation and exhalation phases, on a breath by breath basis, such that each PSA cycle can be dynamically varied from a succeeding PSA cycle, in real time in response to variations in the user's breathing cycle. An oxygen delivery device including a breathing cycle sensor provides breathing cycle inputs to a controller for use with at least one algorithm to detect breathing flow phases during each user breath, and to synchronize each PSA cycle to the user's breathing flow phases, on a breath-by-breath basis. |
US10946158B2 |
Patient interfaces
The present invention relates to a device for delivering a supply of gases to a patient. The device includes a patient interface and connecting member. The connecting member is preferably a L-shaped swiveled connector that is capable of being fixed into one of two positions, a first position where the connector is freely rotatable within the patient interface, and a second position where an interference between the interface and connector prevents the free rotation of the connector within the patient interface. The present invention further relates to a connector that has outlet means, which includes at least one outlet vent and a funnel, which in use directs and passes a substantial portion gases expired from the patient through the outlet vent or vents. |
US10946151B2 |
Ultrasonic measurements for monitoring patients using respiratory therapy delivery devices
Systems and methods for delivering therapy and/or medicament to a subject use one or more sensors to generate signals that represent characteristics of ultrasonic energy emitted during the use of respiratory medicament delivery devices. Parameters based on these signals indicate energy amplitude in one or more frequency ranges. Such parameters can be used to characterize the emitted ultrasonic energy and control and/or monitor device operation and/or patient adherence. |
US10946149B2 |
Apparatus for supplying a breathing gas
An apparatus for supplying a breathing gas at a pressure level that at least in some phases is above ambient pressure includes a blower device including an impeller and a housing device to receive the impeller. A suspension device is structured to support the blower device. The suspension device includes a variable suspension characteristic. |
US10946146B2 |
Syringe driving apparatus and system
A syringe driving apparatus includes a housing, a driving member disposed in the housing and a resilient member connected to the housing and the driving member. The housing having a front end, a back end and a compartment between the front end and the back end, the compartment is configured to receive a plunger of the syringe therein. The driving member is movable relative to the housing between the front end and the back end. Movement of the driving member towards the back end deforms the resilient member to store potential energy in the resilient member, and upon release of the potential energy, the resilient member moves the driving member towards the front end to press the plunger to expel medicine out of the syringe. |
US10946145B2 |
Device for intraocular fluid injection
Devices and methods for intraocular fluid injection are disclosed. A device can include a surgical instrument for an ophthalmic procedure. The surgical instrument can include a handle. A fluid compartment can be coupled to the handle and configured to hold a substance. A tool can be coupled to the distal end of the handle and have a lumen configured to convey the substance into an intraocular site of a patient. A piston can be in the handle and configured to reciprocate along the longitudinal axis of the handle to draw the substance from the fluid compartment and eject the substance through the lumen of the tool. A push button can be on the lateral side of the housing and configured to engage the piston via a sloped surface to actuate a forward stroke of the piston towards the distal end of the handle. |
US10946144B2 |
Power efficient accessory device
An add-on device adapted to be releasably attached to a drug delivery device, the drug delivery device comprising an indicator adapted to display a dose amount during dose setting, and to display the remaining dose amount to be expelled during drug expelling. The add-on device comprises an electronically controlled display adapted to display a set dose amount, a sensor assembly adapted to detect movement of the dose setting member when the add-on device is attached to a drug delivery device, a camera device adapted to capture an image of the indicator, and processor means adapted to (i) control the display dynamically to show the set dose amount based on input from the sensor assembly, and (ii) determine an expelled dose amount based on input from the camera device. |
US10946143B2 |
Detection and communication of plunger position using induction
A syringe system, including a plunger, a microcontroller, a battery, and a coil. The syringe barrel having a proximal end, a distal end, and a cylindrical sidewall defining a longitudinal axis, the cylindrical sidewall extending longitudinally between the proximal and distal ends, the sidewall having an exterior surface and defining an internal volume, the plunger being positioned between the proximal and distal ends of the syringe barrel and being movable within the internal volume with respect to the syringe barrel in the longitudinal direction. The syringe barrel further includes a label disposed on the sidewall and having at least two conductive strips extending in a non-parallel direction with respect to the longitudinal axis and having unique lengths. The microcontroller is configured to determine a position of the plunger with respect to the syringe barrel by measuring a current induced in the coil by the at least two conductive strips. |
US10946139B2 |
Disposable assembly for drug infusion with pressure sensing for identification of and injection into fluid-filled anatomic spaces
A disposable fluid flow assembly for operation in connection with a fluid pump configured to provide a flow of fluid to the disposable fluid flow assembly is provided. The disposable fluid flow assembly includes an elongated flexible tube, a needle hub connected with the flexible tube, a pressure sensor for sensing fluid pressure, and an identification circuit embedded connected with the pressure sensor. The identification is configured to provide a plurality of signals to the central controller of the fluid pump when the disposable needle assembly is connected with the fluid pump. The plurality of signals may include various signals, such as a signal to identify physical characteristics of the assembly, a signal to ensure that the assembly is authentic, a signal to ensure that the disposable assembly is not re-used, and/or a signal to ensure that the pressure signal is connected and operating properly. |
US10946138B2 |
Subcutaneous infusion set with side port fluid connector
A method of coupling an extension set hub comprising a blunt cannula, with an infusion set comprising a base, an upper septum, a lower septum, and a septum cap enclosing said upper and lower septa, said septum cap comprising at least one radial port and at least one axial port, the method comprising the steps of affixing said base to a skin surface of a user, moving said extension set hub in a direction substantially parallel to said base until said blunt cannula passes through said radial port and between said upper septum and said lower septum within said septum cap, and rotating said extension set hub about said base until reaching a desired position. |
US10946136B2 |
Delivery device with noise reducing component
A delivery device for delivering a medication to a patient includes a catheter with a catheter insertion mechanism, a housing, and a base with a surface for supporting a pump mechanism. A noise dampening member in or on the device inhibits noise and vibrations from the pump mechanism from transferring through the base and housing. The noise dampening member can be an elastomer that is coated on or adhered to the base. The noise dampening member can be molded in or on the base in a suitable location to dampen noise produced by the mechanical component. The noise dampening member can be between the base and the mechanical component or spaced from the mechanical component. The noise dampening member can be molded in a recessed area formed in the base and can have a top face that is recessed, aligned with or project from the top face of the base. |
US10946134B2 |
Systems and methods for treating blood
According to some embodiments, a system may treat blood outside the body of a patient. The system may include at least one toxin removal system configured to process blood from at least two places on the patient's body at a rate, for example, of at least 0.5 liters per minute. The system may be configured to raise the pH level of the patient's blood by introducing a fluid at rate of at least 9 liters per hour. |
US10946133B2 |
Systems and methods for parallel channel microfluidic separation
The present disclosure describes a system and method for microfluidic separation. More particularly, the disclosure describes a system and method for the purification of a fluid by the removal of undesired particles. The device includes microfluidic separation channels that include multiple outlets. The device also includes isolation slots positioned between each of the microfluidic separation channels. The device's base includes multiple acoustic transducers which in some implementations are configured to protrude into the isolation slots. The acoustic transducers are configured to generate aggregation axes within the separation channels, which are used to separate out undesired particles. |
US10946132B2 |
Access cannula comprising blocking device
An access cannula which includes a dwell tube that serves as an access during treatment. A blocking device that maintains the dwell tube kinked in an idle position. In the idle position, the dwell tube is maintained kinked, preferably at a predetermined kink point that corresponds to a position in which a force exerted by the blocking device upon the dwell tube, the elastic reset force of the dwell tube and, where appropriate, a pressure prevailing in the dwell tube, balance one another. |
US10946128B2 |
Self-contained heart pump
A heart pump includes a rotative impeller partly inserted into the systemic ventricle, this rotative impeller being equipped with a membrane sutured to the outer wall of the heart in such a way as to secure the rotative impeller to the wall of the heart, a housing arranged inside the systemic ventricle in such a way as to draw up then discharge blood, a motor connected to the housing and arranged partly outside the systemic ventricle in such a way as to facilitate maintenance; an integrated management unit in the epigastric region including a power supply and a rotative impeller control unit; and a wired link between the management unit and the rotative impeller. |
US10946122B2 |
Manually-actuated reduced pressure treatment system having regulated pressure capabilities
A reduced pressure treatment apparatus includes a charging chamber storing a first pressure less than an ambient pressure and a regulated chamber storing a second pressure less than the ambient pressure. The first pressure is less than the second pressure. A conduit provides fluid communication between the regulated chamber and the charging chamber. A regulator member is operably associated with the conduit to prevent fluid communication through the conduit when the second pressure is less than or equal to a desired therapy pressure and to allow fluid communication through the conduit when the second pressure exceeds the desired therapy pressure. |
US10946115B2 |
Humidifier with regular addition of fixed quantity of essential oil
A humidifier with regular addition of fixed quantity of essential oil has a main body, and a water storage bucket assembling with the main body. The main body has an opening located on one side, an inner casing corresponding to the opening, and a peristaltic pump provided on a side of the inner casing not facing the opening. The inner casing defines an essential oil bottle accommodation space communicating with the opening, and the essential oil bottle accommodation space is provided for disposing an essential oil bottle storing an essential oil. The peristaltic pump is controlled by the main body, thereby fixed quantity of essential oil is supplied regularly and quantitatively by the humidifier without dismounting the water storage bucket. Thus, fragrance is kept in atomizing air continuously to solve the problem of the conventional humidifier that fragrance merely exists when the essential oil is added initially. |
US10946114B2 |
Microfluidic cartridge
A microfluidic cartridge is provided. The microfluidic cartridge includes a reservoir for containing a fluid composition, a first face, and a second face joined with the first face. The electrical circuit has a first end portion and a second end portion. The first end portion of the electrical circuit is disposed on the first face and the second end portion of the electrical circuit is disposed on the second face. The first end portion includes electrical contacts and one or more circuit minor openings that are configured to mate with minor guideposts on the housing of a microfluidic delivery device. The microfluidic cartridge may include one or more major openings that are configured to mate with major guideposts on the housing. The microfluidic cartridge includes a microfluidic die disposed on the second face. |
US10946113B2 |
Apparatus and system for air cleaning
An air filtering and treatment apparatus (10), the apparatus (10) including: a housing (12) having an air inlet (14), an air outlet (16), an air passageway (24) between the inlet (14) and outlet (16), and a fan (18) arranged to urge air through the air passageway (24) between the air inlet (14) and the air outlet (16), wherein the housing (12) includes filter (20) arranged to filter air passing through the air passageway (24), and a receptacle (26) located toward the air outlet (16) relative to filter (20). The receptacle (26) is adapted to hold treatment composition (22) such that an evaporable vapour associated with the treatment composition (22) is able to accumulate in a headspace (41) of the receptacle (26), the headspace (41) including at least one aperture (36). The air passageway (24) may be shaped such that air flows substantially perpendicularly past the at least one aperture (36) of the receptacle (26) such that a pre-determined amount of the evaporable vapour is entrained into the filtered air released from the air outlet (16). A system (100) and method are also disclosed. |
US10946110B1 |
Systems and methods for providing ultraviolet sterilization, disinfection and decontamination of gaming equipment
Systems and methods for providing ultraviolet (UV) sterilization, disinfection and decontamination of electronic gaming machines (EGMs), gaming chips, dice, playing cards, currency, TITO tickets, etc. The ultraviolet sterilization, disinfection and decontamination may include a plurality of UV LEDs or RGB-UV LEDs of such wavelengths to be effective in reducing or eliminating viruses or the like. Pass through or planar arrays of UV or RGB-UV LEDs are mounted to or installed within a variety of gaming devices or equipment such as EGMs, chip trays, dice holders, automatic card shufflers, bill validators, magnetic card readers, currency counting or currency dispensing devices, printers, etc. |
US10946104B2 |
Aberrant cell-restricted immunoglobulins provided with a toxic moiety
Described are immunoglobulins provided with a toxic moiety, comprising at least an immunoglobulin variable region that specifically binds to an MHC-peptide complex preferentially associated with aberrant cells. These immunoglobulins provided with a toxic moiety are preferably used in selectively modulating biological processes. The provided immunoglobulins provided with a toxic moiety are of particular use in pharmaceutical compositions for the treatment of diseases related to cellular aberrancies, such as cancers and autoimmune diseases. |
US10946103B2 |
Methods of treatment using a branched amino terminal pegylated Il-11 composition
Methods are provided for treating an individual with a pharmaceutical preparation that includes a recombinant IL-11 PEGylated at equimolar to low molar excess of PEG to achieve a highly pure monoconjugate preparation, which provides improved half-life in serum while having desirable therapeutic activity and presenting fewer side-effects. Most preferably, the IL-11 is an N-terminally truncated human or humanized IL-11 and has a 20 Kd or 40 Kd branched PEG moiety, Y- or comb-shaped in particular, coupled to the N-terminal amino group. Such compounds are characterized by substantially increased stability in serum and sustained biological activity while exhibiting significantly reduced plasma expansion. |
US10946098B2 |
Activatable two-component photosensitizers
Provided herein is a two-component photosensitizer, which demonstrated robust and selective killing effects for transfected HEK cells and affibody targeted A431 cancer cells when exposed to near infrared light excitation. Free MG2I is a pure and stable fluorogen; it is easy to synthesize and modify, and has no toxicity to cells. Unlike conventional photosensitizers, the dye and FAP itself has no photosensitizing effect until they are bound. Also unlike other activation methods, the activation step is achieved by adding the fluorogen, not the presence of the targeted molecule, requiring an ‘active’ activation instead of a ‘passive’ activation. This method offers the ability to locally switch-on and selective generation of singlet oxygen at the target site and can be used for a wide variety of molecular targets. |
US10946093B2 |
Methods of treating cancer using PD-1 axis binding antagonists and MEK inhibitors
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and a MEK inhibitor and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer. |
US10946091B2 |
Compositions and methods for treating Crohn's disease and related conditions and infections
In alternative embodiments, the invention provides a “triple combination” therapy for treating, ameliorating and preventing Crohn's Disease (or Crohn syndrome, terminal or distal ileitis or regional enteritis) or related disorders and conditions in mammals, such as paratuberculosis in mammals, or Johne's disease, including genetically-predisposed and chronic disorders, where the microbial or bacterial flora of the bowel is at least one causative or symptom-producing factor; and compositions for practicing same. In alternative embodiments, methods and compositions of the invention comprise or comprise use of therapies, medications, formulations and pharmaceuticals comprising active agents that can suppress or eradicate the microbiota super-infection that causes Crohn's Disease or paratuberculosis infection in mammals. In alternative embodiments, the methods and uses of the invention for treating, ameliorating and preventing Crohn's Disease and complications of Crohn's Disease, or related disorders and conditions in mammals, such as paratuberculosis in mammals, or Johne's disease, comprises administration to an individual (human or mammal) in need thereof: (1) an anti-TNFα composition, or a composition capable of down-modulating TNFα activity; (2) a Hyperbaric Oxygen Treatment, or HBOT; and (3) an anti Mycobacterium avium sub species paratuberculosis (MAP) (an anti-MAP) agent, composition or therapy. |
US10946090B2 |
Consensus/ancestral immunogens
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens. |
US10946084B2 |
Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus
The present invention relates to proteins and nucleic acids derived from Staphylococcus aureus as well as therapeutic and diagnostic uses of the proteins and nucleic acids. |
US10946083B2 |
Anti-microbial immunomodulation
The invention provides methods of modulating an immune system in a vertebrate host for the therapeutic or prophylactic treatment of infection by a first microbial pathogen in a target tissue, comprising administration at an administration site of an effective amount of an antigenic formulation comprising antigenic determinants specific for a second heterologous microbial pathogen. |
US10946078B2 |
Treatment of canine atopic dermatitis
The present invention relates to compositions, immunogenic or vaccine compositions and pharmaceutical compositions for the prevention or treatment of canine atopic dermatitis (CAD). Furthermore, the invention provides methods for preventing or treating CAD. The compositions of the invention induce efficient immune responses, in particular antibody responses, in dogs and are, therefore, useful for the treatment and/or prevention of CAD. |
US10946076B2 |
Glaucoma treatment
Disclosed herein are methods of treatment for an intraocular pressure (IOP)-associated condition in a subject, that include administering to the subject an effective amount of a tissue plasminogen activator (tPA) therapeutic agent. In one embodiment, the IOP-associated condition is glaucoma. The administration of a tPA therapeutic agent can be an extended administration intended to cause a reduction in IOP in the subject for a period of at least one day to a year or more, relative to IOP levels in the subject prior to administration of the tPA therapeutic agent. The tPA therapeutic agent can be, for example, tPA, a tPA derivative, a small molecule direct or indirect tPA agonist, or a gene therapy vector. |
US10946075B1 |
Radioprotection, radiomitigation and radiorecovery
Radioprotection, Radiomitigation and Radiorecovery: Timed use of more widely available antiradiation agents in a kit for subjects affected by ionizing radiation, radiomimetic exposure and radiocontamination. The method in the form of strategically timed preemptive and postirradiation compositions; radioprotection, radiomitigation and radiorecovery formulations are comprised of various available anticorporation, antioxidant, decorporation, multi-mechanistic, pro-survival, pro-hematopoietic, anti-fibrotic and other novel ingredients in synergistic mixtures to be used in critically-timed manners. Radioprotection, radiomitigation and radiorecovery of a mammal prior to, during, just after or well-after exposure to ionizing radiation energy—alpha, beta, neutron, gamma, X-ray and damaging radiofrequency radiation—for long or short periods of time, and exposure to or contamination by radioactive elements or compounds such as radioiodine, radiostrontium, radiophosphorus, radiocobalt, radiocadmium, radiopollonium, radioradium, radiocesium, radiouranium, radioamericium, radiopollonium, radiocerium, radioindium, and the like. Radiomimeticprotective method for mucosal exposure is also described. |
US10946072B2 |
Method for treating dermatitis and improving skin texture using B-type natriuretic peptides
The problem to be solved by the present invention is to provide a safe and efficacious therapeutic agent for dermatitis which is not only safe and efficacious for patients with dermatitis, in particular atopic dermatitis, but also significantly effective for severe cases that are judged to be intractable by conventional external preparations, and which is also safely applicable to affected areas such as the face and neck, as well as to subjects with sensitive skin, such as infants and females. Furthermore, the invention aims to provide an external preparation that is efficacious as skin care cosmetics having effects to improve elasticity and wrinkles of the skin, moisturizing effects, and hair-growth effects. The means for solving the problem is a skin external-preparation composition, in particular, a therapeutic agent for dermatitis or a skin texture-improving agent, having C-type natriuretic peptide (CNP) or B-type natriuretic peptide (BNP) as the active ingredient. |
US10946071B2 |
Combination of ibudilast and interferon-beta and methods of using same
This disclosure is directed to methods of alleviating the negative effects of, treating, or slowing the progression of progressive multiple sclerosis in human patients using ibudilast and interferon-beta. |
US10946070B2 |
Targeted and mutated human-interferon fusion proteins
This disclosure relates to a modified α-helical bundle cytokine, with reduced activity via an α-helical bundle cytokine receptor, wherein the α-helical bundle cytokine is specifically delivered to target cells. Preferably, the α-helical bundle cytokine is a mutant, more preferably it is a mutant interferon, with low affinity to the interferon receptor, wherein the mutant interferon is specifically delivered to target cells. The targeting is realized by fusion of the modified α-helical bundle cytokine to a targeting moiety, preferably an antibody. This disclosure relates further to the use of such targeted modified α-helical bundle cytokine to treat diseases. A preferred embodiment is the use of a targeted mutant interferon, to treat diseases, preferably viral diseases and tumors. |
US10946069B2 |
Combination therapy involving antibodies against claudin 18.2 for treatment of pancreatic cancer
The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as pancreatic cancer and metastases thereof. |
US10946064B2 |
Personalized immunotherapy against several neuronal and brain tumors
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses. |
US10946059B2 |
Formulation containing an extract of Alpinia galanga, a process for the preparation thereof, and uses thereof
Various embodiments relate to formulations containing an extract of Alpinia galanga; a method of improving cognitive performance by administering an extract of Alpinia galanga; and a process for preparing an extract of Alpinia galanga. |
US10946055B2 |
Method of synthesizing custard apple peel nanoparticles
The custard apple peel nanoparticles may be manufactured by extracting custard apple peels in a solvent, spraying the custard apple peel extracts into boiling water under ultrasonic conditions to produce a first mixture, sonicating the mixture, stirring the mixture, and drying the mixture to obtain custard apple peel nanoparticles. In an embodiment, the custard apple peel may be peel of Annona reticulata. In an embodiment, the custard apple peel nanoparticles may have improved antibacterial or antioxidant properties. |
US10946050B2 |
Compositions comprising probiotics and methods of use thereof
The present invention provides compositions comprising a probiotc in admixture with an effective amount of an amphipathic substance that enhances viability of the probiotic in the composition when the composition is subjected to heat. |
US10946049B2 |
Use of gram negative species to treat atopic dermatitis
Pharmaceutical compositions are disclosed that includes a therapeutically effective amount of a purified viable Gram negative bacteria and a pharmaceutically acceptable carrier. The pharmaceutical compositions are formulated for topical administration. Methods of treating atopic dermatitis using these pharmaceutical compositions are also disclosed. |
US10946047B2 |
Extracellular vesicles with enhanced potency
Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions associated with mitochondrial dysfunction. |
US10946039B2 |
Chitosan acrylic acid derivative hemostatic powder
The present invention provides a hemostatic powder. The hemostatic powder is mainly present in the form of a columnar particle, wherein the ratio of axial length to diameter of the columnar particle is less than 5; the hemostatic powder includes a polymer represented by the following structural formula: wherein the R is at least one selected from the group consisting of —NH2, —OCH2CH2OH, —OCH2CH2CH2OH, —OH, —ONa, —OK and —OCa; m, n and p respectively represent number percentages of corresponding repeating units in polymer molecules, and satisfy the following equations: m+n+p=1, p/(m+n+p)=0.05˜0.30; the substitution degree D is defined as =m/(m+n+p), the overall substitution degree of the columnar particle is defined as Ds, the substitution degree of the polymer at the center point of the cross section of the columnar particle is defined as Do, and the substitution degree of the polymer at the edge of the cross section of the columnar particle is defined as Dx, and the following equations are satisfied: Ds=0.09˜0.8, Do/Dx=0˜0.7. |
US10946038B2 |
Cancer treatment using beta-(1-3)-(1-4)-glucan
A method of treating a subject having cancer is described that includes administering a therapeutically effective amount of a β-(1,3)-(1,4) glucan to the subject. Methods of immunostimulating in a subject by administering an effective amount of a β-(1,3)-(1,4) glucan to the subject are also described. |
US10946034B2 |
Methods for the use of 5′-adenosine diphosphate ribose (ADPR)
The present invention is directed to methods for the use of 5′-adenosine diphosphate ribose (ADPR), and compositions thereof, for treating, managing, or preventing RNA virus-related diseases or conditions, herpes virus related diseases or conditions, Sirtuin 6 (Sirt6)-related diseases or conditions, Pax6 related diseases or conditions, and p53 related diseases or conditions. |
US10946032B2 |
Mixtures of HMOs
The invention relates to a mixture of human milk oligosaccharides that consists essentially of: a) a component A which is 3-FL or DFL, a component B which is LNT, LNnT, LNFP-I or 2′-FL, a component C, which is LNFP-II when component B is LNT, or LNFP-III when component B is LNnT, or LNDFH-I when component B is LNFP-I, or DFL when component B is 2′-FL, and a component D, which is lactose when component A is 3-FL, or 2′-FL when component A is DFL, with the proviso that if component B is 2′-FL, then component A is 3-FL; or consists essentially of: b) 3-FL, a component E which is LNT, LNnT or LNFP-I, and a component F, which is LNFP-II when component E is LNT, or LNFP-III when component E is LNnT, or LNDFH-I when component E is LNFP-I, and to processes for producing them and their uses. |
US10946025B2 |
Compounds
The invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity. |
US10946020B2 |
Compositions and methods for treating cancer
Ritanserin is shown to be an inhibitor of diacylglycerol kinase alpha (DGKα) and to be cytotoxic to glioblastoma and melanoma cells. Ritanserin treatment also provides chemo- and radiosensitization in cancer cells, prolonged survival in mouse models of glioblastoma, decreased melanoma tumor burden in mice, and shows synergistic cytotoxic effects with temozolomide and chloroquine, both singly and in combination. DGKα inhibition with ritanserin shows particular toxicity to the treatment-resistant mesenchymal subtype in glioblastoma and other cancers. |
US10946012B2 |
Methods for inducing tumor regression, inhibiting tumor growth, and inducing apoptosis in breast tumors with geranylgeranyltransferase I inhibitors
Methods of inducing tumor regression, inhibiting tumor growth, and inducing apoptosis with selective peptidomimetic inhibitors of geranylgeranyltransferase I (GGTase I), are provided. In one aspect, GGTI-2418 and its methylester GGTI-2417, increase levels of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 and induce breast tumor regression in vivo. In another aspect, GGTI-2417 inhibits the Cdk2-mediated phosphorylation of p27Kip1 at Thr187 and accumulates p27Kip1 in the nucleus. |
US10946011B2 |
Stable oral liquid formulation of trimetazidine
Disclosed is a stable oral liquid pharmaceutical composition of trimetazidine having a pH of about pH 4 to about pH 8, comprising a therapeutically effective amount of trimetazidine or a pharmaceutically acceptable salt thereof, one or more orally acceptable buffers, and one or more orally acceptable preservatives that is effective in said pH range. Also disclosed are methods of treating patients with stable oral liquid pharmaceutical composition. The pharmaceutical composition is particularly suitable for treating a patient having a condition treatable by trimetazidine, such as cirrhosis and renal deficiency, and who has a decreased tolerance for acidic or highly basic oral solutions. |
US10946009B2 |
Combination dosage form of a mu opioid receptor antagonist and an opioid agent
The invention provides a solid composition of the peripheral mu opioid antagonist axelopran and a combination dosage form of the mu opioid antagonist axelopran sulfate in an immediate release form and an opioid analgesic agent which may be in an extended release, sustained release, modified release, or controlled release form and methods of preparing such a combination dosage form. |
US10946007B2 |
4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds
The invention relates to compounds of formula I: where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds. |
US10946005B2 |
Methods for shrinking pituitary tumors
Pituitary tumors may be reduced in size by administration of relacorilant. Pituitary tumors include, without limitation, non-secreting tumors, hormone-secreting tumors, adenomas, and carcinomas. Relacorilant administration may be effective to reduce hormone secretion from a hormone-secreting pituitary tumor, e.g., to reduce adrenocorticotrophic hormone (ACTH) secretion. A pituitary tumor may be imaged before and/or after relacorilant administration. Relacorilant may be administered independent of surgery, and before, during, or after surgery to treat a pituitary tumor. Relacorilant may aid or improve surgical outcomes, and may reduce the size or growth of pituitary tumor tissue before surgery, and any tumor tissue remaining following surgical treatment.Relacorilant may be orally administered for the treatment of pituitary tumors. Relacorilant may be orally administered to a fasted patient, or to a fed patient. Relacorilant may be administered in conjunction with other pituitary tumor targeting treatments, including surgical treatments, radiation treatments, chemotherapy for carcinomas, and other pharmaceutical treatments. |
US10946004B2 |
Solid forms of an ASK1 inhibitor
Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms. |
US10946002B2 |
Pharmaceutical suspension dosage form of benzimidazole compounds and process of preparation thereof
The present invention relates to a solid oral pharmaceutical dosage form suitable for making a suspension comprising acid labile benzimidazole compounds and process for preparing the same. The prior art discloses various technical challenges associated with the granules for reconstitution into suspension like agglomeration of particles, viscosity and gelling time. The solid oral pharmaceutical dosage form of the present invention forms a homogeneous suspension upon admixing with an aqueous medium and exhibits desired technical attributes like viscosity, drug release, gelling time, dissolution and reduced adherence to nasogastric and gastric tubes. |
US10946000B2 |
Method for treating cancer with combination therapy
Provided are methods for treating cancer in a patient by administering at least one antibiotic selected from the group consisting of clofazimine, rifabutin and clarithromycin, in combination with an aryladamantane compound. In an embodiment, the aryladamantane compound is [3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide], or a pharmaceutically acceptable salt thereof. |
US10945996B2 |
Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis
Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C. perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
US10945995B2 |
Compositions and methods for channelopathy disorders-targeting fluid movement across membranes
The present invention includes composition and methods for treating stroke comprising: identifying a subject in need of treatment for a stroke; and providing the subject with a therapeutically effective amount of an Aquaporin-4 inhibitor that blocks a filter portion of an Aquaporin-4 channel region, and identifying modulators of the different aquaporin specific splice variants. |
US10945994B2 |
Combinations comprising a pyrrolidine-2,5-dione IDO1 inhibitor and an anti-body
Combinations of an IDO1 inhibitor (e.g., a 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione compound), with an anti-PD1 antibody or anti-PD-L1 antibody, and an anti-4-1BB antibody, as selected anti-cancer or anti-viral agents are provided. Also provided are use of these combinations for the treatment and/or prevention of cancer and endometriosis. |
US10945992B1 |
Dosage forms of rofecoxib and related methods
The subject matter disclosed herein relates to novel doses and dosage forms of rofecoxib having a therapeutic benefit. |
US10945990B2 |
Combination of a PD-1 antagonist and eribulin for treating cancer
The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and eribulin or a pharmaceutically acceptable salt thereof, and the use of the combination therapies for the treatment of cancer. |
US10945987B2 |
Method for providing early onset of action in the treatment of rosacea
A regimen is described for providing early onset of action in the therapeutic treatment of rosacea including topically applying a pharmaceutical composition to the skin of a subject in need of said treatment. The pharmaceutical composition includes about 1% to about 10% benzoyl peroxide as the only active ingredient, and a pharmaceutically acceptable carrier or excipient. The pharmaceutical composition is applied once daily for a period of at least about 2, 4, 8 or 12 weeks. Based on early onset of action, a primary measure of success is at least about 9%, primary measure of success being defined as a 2-grade improvement in IGA of clear or almost clear; and a secondary measure of success is at least about 40%, secondary measure of success being defined as mean inflammatory lesion count percent reduction from baseline, after at least about 2 weeks of treatment. |
US10945985B2 |
Fumarate ester dosage forms
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability. |
US10945982B1 |
Nasal hygiene method and composition
A composition for and method of practicing nasal hygiene to wash and moisturize the nasal passage. Where the nasal wash comprises a liquid homogenized compound of water, chlorine dioxide (or source thereof), olfactory stimulants, unsaturated fatty acids, inorganic salt, fixing agents. Where the unsaturated fatty acid component comprises from 0.1% to 3% by weight of the compound. |
US10945981B2 |
Methods for treating familial adenomatous polyposis
Provided are methods for preventing or delaying the need for surgical intervention in a patient having familial adenomatous polyposis (FAP) and an at least partially intact lower gastrointestinal tract. Also provided are methods for preventing or delaying the formation of neoplasia and/or cancer in a patient having FAP. The methods comprise administering an effective amount of a pharmaceutical therapy that comprises eflornithine and sulindac to a patient having FAP and an intact lower gastrointestinal tract. |
US10945974B2 |
Methods and compositions to modulate the gut microbiota and to manage weight
Methods of weight management for a subject are provided. Generally the methods comprising: administering an effective amount to the small intestine and/or large intestine of the subject of at least one agent that increases oxygen tension and/or redox potential and/or pH in the colon of the subject to thereby manage the weight of the subject. Also provided are compositions comprising at least one agent that increases oxygen tension and/or redox potential and/or pH, wherein the composition is formulated for delivery of an effective amount of the at least one agent to the small intestine and/or large intestine of a subject following oral ad ministration of the composition to the subject. |
US10945965B2 |
Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
The present invention relates to novel nanoparticles which can be advantageously used in the health sector as diagnostic and/or therapeutic agents. Nanoparticles of the invention comprise a metallic material at least partly covered with a hafnium oxide material or embedded therein. When compared to existing products, these nanoparticles offer a remarkable benefit over risk ratio. Specifically, these nanoparticles potentiate the efficiency of known metallic nanoparticles. Indeed, they retain the metal's intrinsic properties and are now in addition safely usable in a mammal, in particular in a human being. The invention also relates to methods for producing said nanoparticles, to compositions containing same, and to uses thereof. |
US10945964B2 |
Microencapsulated chitosan, methods of making and methods for the use thereof
Provided herein are microencapsulated chitosan materials and formulations containing same, methods of making such formulations, and methods of using such formulations. Application of a microencapsulation coating on chitosan materials and formulations containing same renders possible the use of chitosan materials for different, novel chitosan-based dietary applications with the primary aim to decrease intestinal absorption of fat and enhance overall health, without interfering with or reducing food palatability. The present invention provides methods to microencapsulate highly effective chitosan or chitosan salts to moderate their interaction with food components and mask any off-flavors and off-tastes but allow rapid chitosan solubilization under gastric acid conditions and simultaneous binding of ingested lipids. Chitosan contemplated for use herein is preferably of high quality with high fat-binding capacity, and its source is preferably of crustacean origin. |
US10945961B2 |
Method using enteric-coated etidronate for treating calcification, hypercalcaemia, and calcinosis of the brain and other organs
Among other things, compositions, kits, and methods for epilepsy therapy using a process for treating calcinosis manifested in Neurocysticercosis, Tuberous Sclerosis Complex, and Sturge-Weber Syndrome; an automated platform for real-time diagnosis and treatment of calcinosis comprising a computer-implemented method for using predictive analytics for administering a novel drug, Kamini™, to human patients generated at least in part from information that has been accumulated automatically from on-line resources. |
US10945960B2 |
Celecoxib and amlodipine formulation and method of making the same
Provided herein is a celecoxib and amlodipine composition and method of making the same. The composition contains granules containing celecoxib. The amlodipine is incorporated into the composition as an extragranulate. |
US10945957B2 |
Biodegradable nano-theranostic composite and process of preparation thereof
A biodegradable nano-theranostic composite comprising graphene oxide and lipid in the liposomes in the ration of 0.005 to 0.03 characterized in that the graphene oxide is coated as film on the liposome on the inner side and outer side of the liposome. The composite is capable of safely carrying sensitive cargo without premature release and is fluorescent and absorbs in the NIR region and can perform targeted combined chemo and photothermal therapy. The nanotheranostic nanocomposite is designed to collapse and biodegrade after use. |
US10945956B2 |
Biodegradable compound, lipid particles, composition and kit comprising lipid particles
[Problem]To provide a biodegradable compound having a structure decomposed in a cell, lipid particles containing the compound, and a pharmaceutical composition comprising the lipid particles.[Solution]The compound of the embodiment is represented by the formula (1): P—[X—R—Y—R′-Q]2 (1). In the formula, P is an alkyleneoxy having an ether bond, X is a divalent linking group having a tertiary amine structure, R is a divalent linking group, R′ is a single bond or a C1 to C6 alkylene, and Q is a liposoluble vitamin residue, a sterol residue, or a C12 to C22 aliphatic hydrocarbon group. The structure of the compound contains at least one biodegradable group. From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells. |
US10945951B2 |
Apparatus for compound dispersion
Methods and apparatuses for dispersing a compound within the patient are described. In one embodiment, an effective amount of a compound may be present in the cerebrospinal fluid of a patient and a force may be applied to the torso of the patient sufficient to enhance the convection of the cerebrospinal fluid. In another embodiment, a bolus including a compound may be injected into the cerebrospinal fluid of a patient. The volume of the bolus may be between about 5% and 30% of the total volume of the cerebrospinal fluid of the patient. |
US10945948B2 |
Compositions and methods for ophthalmic and/or other applications
Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye. |
US10945943B2 |
Extract of dragon fruit flower, method for preparing the same, use thereof, and skin complexion improved composition thereof
The present invention provides an extract of dragon fruit flower. The extract of dragon fruit flower is prepared by the following steps. A dragon fruit flower is provided. The dragon fruit flower is dried and then cut into pieces. An extraction process is provided, which includes a mixing step, a heating step, a cooling step, a reheating step, and an extracting step. In the mixing step, the pieces of the dragon fruit flower are mixed with an alcohol solution to obtain a mixture for processing the following steps. After finishing the extraction process, the mixture is separated into a solid part and a liquid part, wherein the liquid part includes the extract of the dragon fruit flower. |
US10945932B2 |
Prebiotic oral care compositions containing carboxylic acids
The present invention provides an oral care composition comprising a carboxylic acid of the formula (I) wherein: R1 is H, or is a substituted or unsubstituted alkyl group; and R2 is H, OH, or NH2; for use in: (a) selectively promoting, in an oral cavity: growth, metabolic activity or colonization of bacteria that have beneficial effects on oral health, relative to growth, metabolic activity or colonization of pathogenic oral bacteria; (b) selectively promoting, in an oral cavity, biofilm formation by bacteria that have beneficial effects on oral health, relative to biofilm formation by pathogenic oral bacteria; or (c) maintaining and/or re-establishing a healthy oral microflora. |
US10945931B2 |
Shaping keratin fibres using dialdehyde compounds
Described herein is a method for shaping keratin fibres including (i) providing a crosslinking composition comprising from about 1% to about 20% of a dialdehyde compound, optionally a photocatalyst, and a cosmetically acceptable carrier; (ii) applying the crosslinking composition to keratin fibres; and (iii) mechanically shaping the keratin fibres with an appliance at a temperature of about 50° C. to about 280° C. |
US10945927B2 |
Phosphate-based dental investment material
To provide a phosphate-based dental investment material which can used for metal and press ceramic and especially can impart the lubricity to the surface of a press ceramic, and a phosphate-based dental investment material which can be subjected to a flash heating for press ceramic, can obtain sufficient the hardening expansion, and can easily remove the investment material after press molding. A phosphate-based dental investment material of the present disclosure comprising a powder material and a liquid material, wherein the powder material contains (a) magnesium oxide: 5 to 20 wt. %; (b) ammonium dihydrogenphosphate: 8 to 25 wt. % and the liquid material contains (c) aqueous solution including a cation-treated colloidal silica. |
US10945923B2 |
Production line for the production of medicinal products and production plant comprising such a production line
A production line is, suitable for the production of medicinal products that include at least one active ingredient. The production line includes an extruder for producing an extrudate from the active ingredient and at least one excipient intended to form an encapsulating matrix of the active ingredient, and a cooling member for cooling the extrudate at the outlet of the extruder. The extruder includes a barrel and at least two parallel screws housed in the barrel and interpenetrating with one another to mix the or each active ingredient with the or each excipient. The barrel is oriented vertically and the footprint occupied by the production line is less than 0.5 m2. |
US10945918B2 |
Method and apparatus for producing primary packaging having an integrated septum and primary packaging having an integrated septum
The invention relates to a method for producing primary packaging having an integrated septum characterised by: a) providing a septum, b) providing an injection-molding die having two die halves, c) positioning the septum in the injection-molding die, d) moving the two die halves of the injection-molding die to form a cavity corresponding to the shape of the primary packaging to be produced, e) injecting a material into the cavity via an injection opening, where the two die halves of the injection-molding die pretensioningly holding the septum, and a rim of the septum is overmolded by the material, f) cooling the injected material while maintaining a holding pressure, g) moving the two die halves of the injection-molding die such that the produced primary packaging means having the integrated septum can be removed from the injection-molding die, and h) removing the produced primary packaging having the integrated septum from the injection-molding die. |
US10945914B1 |
Accessory for adult toy, and system and method for providing adult entertainment implementing adult toy
An accessory for an adult toy is disclosed. Herein, the adult toy has a vibration motor and a controller configured to actuate the vibration motor by generating an actuation signal. The accessory comprise a body adapted to be mounted on the adult toy. The accessory also comprises a light source arranged inside the body. The accessory further comprises a control circuit. The control circuit is configured to control the light source upon actuation of the vibration motor by the controller. A system and a method implementing the adult toy with the accessory for providing adult entertainment are also disclosed. |
US10945913B2 |
Roller massage system
A roller massage system provides a pair of roller massage assemblies in opposed adjustable spaced relation to allow engagement of each one of the pair of roller massage assemblies on a corresponding massageable portion of the body. |
US10945911B2 |
System for adjusting pressure locally on the skin and subcutaneous tissue
A system for adjusting pressure locally acting on the skin including a set of adjacent modules distributed so as to form a layer each module includes a cushion capable of changing shape and comprising a cavity, a valve, a tank, and a pressure sensor, wherein the cavity and the tank are in communication with each other by means of the valve, and the sensor is placed so as to sense pressure directly or indirectly acting on the cushion and a feedback loop arranged such as to increase or decrease the change in the shape of the cushion on the basis of the pressure detected by the sensor. |
US10945910B2 |
Standing frame for users with standing challenges and method
A standing frame to assist a user with stand challenges in standing, comprising a base assembly that accommodates the user's feet; a stand assembly supported by the base assembly; a handlebar assembly supported by the stand assembly and configured to receive one or more of a user's hands and arms to rest thereon; a securement assembly coupled to the stand assembly to secure the user to the standing frame; and a knee support assembly configured to receive the user's knees to rest thereon. |
US10945908B2 |
Walking assistance method and apparatuses performing the same
A walking assistance method may include receiving at least one abnormal gait type selected from a plurality of abnormal gait types, and differently controlling a walking assistance apparatus based on the at least one abnormal gait type. Therefore, the walking assistance method may effectively assist various types of abnormal gaits. |
US10945907B2 |
Motion assistance apparatus
A motion assistance apparatus including a support link to be attached to a waist of a user, a thigh link connected to a first end of the support link, a knee link connected to a first end of the thigh link, a connecting link connected to a first end of the knee link, and selectively connected to a second end of the support link, and an actuator configured to rotate the knee link with respect to the thigh link is provided. |
US10945905B2 |
System, apparatus and method for supporting and/or positioning a patient before, during, or after a medical procedure
A system for supporting or positioning a patient before, during, or after a medical procedure can include a platform configured to support at least a portion of a patient. A support column can be positioned beneath the platform. A base can be positioned beneath the support column and configured to support the support column. The base can include at least one drive wheel configured to contact a ground surface and move the platform with respect to the ground surface. A drive assist user interface module can be operatively connected to the at least one drive wheel. The drive assist user interface module can be configured to permit an operator of the system to selectively control movement of the at least one drive wheel. The drive assist user interface module can be part of or be attached to an attachment that includes a plate having a top surface. In one configuration, the top surface of the plate can be configured to extend parallel with a top surface of the platform when the attachment is attached to the platform. |
US10945903B2 |
Method and apparatus for extracorporeal support of premature fetus
A system configured to support growth and development of a premature fetus is disclosed. Specifically, a method and apparatus configured to provide extracorporeal support for premature fetuses is disclosed. |
US10945899B2 |
Removable power assist for manual wheelchair
Disclosed is a device for converting a manual wheelchair into an electronic wheelchair is provided. The device includes a joystick, a communication unit, a motor, a retractable friction roller, an engagement unit and a power source. The joystick is operably connected to a communication unit. The communication unit is operably connected to a motor. The motor includes an axle connected to a rotor. The retractable friction roller is mounted on the axle. The roller is placed in contact with a wheel of a manual wheelchair. The engagement unit is attached to the manual wheelchair to detachably attach the friction roller and the wheel. The power source is operably connected to the motor and the joystick. |
US10945896B1 |
Platform lift with enhanced occupant sensing, platform lighting and locking
A lift for a vehicle includes a platform configured to support an occupant thereon, a parallelogram mechanism to move the platform between a stowed position and a deployed position, a base to mount the parallelogram mechanism to a vehicle floor, a hydraulic system to move the platform through the parallelogram mechanism, a mechanism to fold and unfold the platform, an occupant retention device, a control unit to control a movement of the platform. The occupant retention device can include any one of a belt, a bridgeplate and a roll stop. The lift can also include a platform movement control device that can be provided as an acoustic sensor array, a bridgeplate lock and a platform stow lock. A light assembly can be mounted on the platform as a visual warning of the platform operation. The power connection to the control unit can include an encapsulated decouplable power interface. |
US10945894B2 |
Devices and methods for directing a medical fabric into a portion of the body
A device (10) for directing a medical fabric (28) into a portion of a body. An elongated housing (12) having a distal end (16) and an opening (22) at the distal end (16). A supply of medical fabric (28) in the housing (12). An actuator (24) spaced from said opening (22) and configured to advance a portion of the medical fabric (28) through said housing (12) and out of the opening (22). |
US10945892B2 |
Incontinence detection system and detectors
An incontinence detector includes a layer of material having uniformly distributed electrically resistive elements which impart a baseline electrical resistance to the layer. The layer also has an actual electrical resistance. The detector also includes an RFID tag having a first and second leads which extend into the material without contacting each other. The tag is responsive to deviations of the actual resistance from the baseline resistance. |
US10945885B2 |
Intraocular device for dual incisions
A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues. |
US10945879B2 |
Systems, devices and methods for neurostimulation having a modulation of packets
A method of neurostimulation may include delivering an electrical signal to a plurality of electrodes connected to a patient. The electrical signal may include a plurality of spaced-apart packets of electrical pulses. The method may include modulating at least one of a quantity of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, a width in time of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, an amplitude in voltage of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, a separation in time between adjacent ones of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, and a separation in time between adjacent ones of the plurality of packets of electrical pulses to modulate the electrical signal. |
US10945876B2 |
Fluency aid
The present disclosure provides a fluency aid comprising: a masking signal generator; a switch operable to switch the masking signal generator between an ON state and an OFF state, wherein, when in the ON state, the masking signal generator is operable to generate a masking signal; a sound generator operable to receive the masking signal from the masking signal generator and generate a masking sound for output to a user of the fluency aid; and a voice detector operable to detect a voice of the user, wherein the masking signal generator is operable to generate the masking signal at least until the voice of the user is detected by the voice detector. |
US10945875B2 |
Device for treatment of sleep apnea or snoring
A device for treatment of sleep apnea or snoring of a user which has an upper oral splint adapted for an upper jaw of the user, and a lower oral splint adapted for a lower jaw of the user. At least one of the oral splints has adjustment devices on them, with a fixation device for adjustable and detachable fixation of an abutment element. Since the abutment elements are adjustable and detachable, a flexible device is provided where the setting can be adjusted and parts can be replaced when needed. |
US10945874B2 |
Custom-formable night grinding appliance and method of use
Disclosed is a dental appliance composed of a thermo-plastic polymer with low compressibility, high toughness, and high tensile strength, with a low softening point. The appliance has perforations that enable it to be easily custom-fitted by the user or a health professional. The appliance begins as a generally U-shaped, unformed dental tray that is significantly thinner than existing dental appliances. Once fitted, the dental appliance provides superior protection against damage to the enamel of the teeth and abrasion of the teeth due to bruxism or other mechanism leading to biomechanical wear of dental surfaces. The perforations facilitate the custom-fitting process by allowing the user to suck air through the perforations, thus applying a negative pressure between the material and the teeth while the material is still soft and pliable. This enables a user or health professional to within minutes create a final product that rivals the quality and fit of an appliance made by dental laboratories using dentist made impressions. |
US10945873B2 |
Multi-petaled mounting members for ostomy pouches
A multi-petaled mounting member for an ostomy pouch is disclosed. The mounting member comprises a flexible plastic member comprising a central body portion, a surrounding rim, and an outer perimeter, a first double-sided adhesive substrate member comprising a first face, an opposite second face, and an outer perimeter, a second double-sided adhesive substrate member comprising a first face, an opposite second face, and a multi-petaled outer perimeter, and an adhesive skin barrier member comprising a first face, an opposite second face, and a multi-petaled outer perimeter. The perimeters of the first member and the adhesive skin barrier member substantially correspond in size and shape to the perimeters of the flexible plastic member and the second member, respectively. The perimeter of the second member has a size greater than the perimeter of the flexible plastic member and a shape corresponding to 2 to 8 petals extending radially from the second member. |
US10945869B2 |
Low profile stent delivery system and method
A low profiled stent delivery system includes a balloon catheter with a balloon mounted at a first location, and a balloon expandable stent crimped about the balloon catheter at a second location. The stent expands from a crimped state to a less than fully expanded state responsive to movement of an auxiliary expander from a first configuration to a second configuration. An inner diameter of the stent in the less than fully expanded state is greater than an outer diameter of the balloon in a deflated state. After repositioning the balloon within the less than fully expanded state, the balloon is inflated to fully expand the stent. |
US10945864B2 |
System and method for noninvasive identification of cognitive and behavioral goals
A brain machine interface system for use with an electroencephalogram to identify a behavioral intent of a person is disclosed. The system includes an electroencephalogram configured to sense electromagnetic signals generated by a brain of a person. The electromagnetic signals include a time component and a frequency component. A monitor monitors a response of the person to a stimulus and a characteristic of the stimulus. A synchronization module synchronizes the sensed electromagnetic signals with the response and the characteristic to determine a set of electromagnetic signals corresponding to the monitored response and the characteristic. A processor processes the set of electromagnetic signals and extracts feature vectors. The feature vectors define a class of behavioral intent. The processor determines the behavioral intent of the person based on the feature vectors. A brain machine interface and a method for identifying a behavioral intent of a person is also disclosed. |
US10945858B2 |
Expandable interspinous process fixation device
An expandable interspinous process fixation system capable of restoring spinal stability and facilitating fusion. In one embodiment, the expandable interspinous process fixation system includes a central ramp, a first endplate, and a second endplate, the central ramp capable of being moved in a first direction to move the first and second endplates outwardly and into an expanded configuration. Each endplate supporting fixed and/or adjustable spinous process engaging plates. |
US10945856B2 |
Spinal interbody with compressive fusion features
An interbody spacer for a spine includes a housing having a plurality of clearance holes configured to engage bone of the spine. A contact plate including a plurality of apertures is positioned a distance away from the housing configured to engage bone of the spine. A plurality of rivets adjoin the housing and the contact plate. A plurality of springs are included with each spring configured to encircle a respective rivet and translate the distance between the housing and contact plate from a minimum distance to a maximum distance. |
US10945850B2 |
Interconnected implants and methods
An apparatus, system, and method may be used to replace a natural or artificial articular surface of a joint, and to repair a bone that is associated with the joint. In some embodiments, the apparatus, system, and method may include a joint replacement prosthesis with a prosthetic articular surface, a support structure securable to the bone, and a first attachment interface. The system may also include a bone plate with a bone engagement surface securable to the bone on either side of a fracture formed in the bone, or a damaged area of the bone. The bone plate may include a second attachment interface that is attachable to the first attachment interface of the joint replacement prosthesis in order to couple the bone plate to the joint replacement prosthesis. |
US10945846B2 |
Implants for bone and cartilage repair
An implant for the repair of bone and cartilage that includes a cell conductive zone that contains biopolymeric fibers and an osteoconductive zone that contains biopolymeric fibers and calcium-containing mineral particles. The biopolymeric fibers from one zone overlap with the fibers in the other zone forming a stable physical and mechanical integration of the two zones, thus conferring in vivo stability to the implant. |
US10945845B2 |
Tissue repair devices and scaffolds
The present invention relates to multiphasic, three-dimensionally printed, tissue repair devices or scaffolds useful for promoting bone growth and treating bone fracture, defect or deficiency, methods for making the same and methods for promoting bone growth and treating bone fracture, defect or deficiency using the same. The scaffold has a porous bone ingrowth area containing interconnected struts surrounded by a microporous shell. At the ends of the scaffold, the shell may be extended as a guide flange to stabilize the scaffold between ends of bone. The center of the scaffold may be empty and may serve as a potential marrow space. The porous ingrowth structure may be infiltrated with a soluble filler or carrier, such as, for example calcium sulfate which may be infiltrated with one or more of an antibiotic, a growth factor, a differentiation factors, a cytokine, a drug, or a combination of these agents. |
US10945842B2 |
Annular augmentation device for cardiac valve repair
The present disclosure relates to repair devices for repair of regurgitant mitral valves. A repair device includes a body having a perimeter defining an upper side and a lower side. An annular groove is disposed along a posterior section of the perimeter of the device and is configured to receive posterior rim tissue of a mitral valve annulus. First and second anchors extend from the body in an anterior direction. The first and second anchors are configured to engage with respective commissures of the mitral valve to assist in securing the repair device in position. The repair device is structured to minimize or eliminate imparting or transmitting radially outward forces along an anterior section so as to avoid imparting forces to the septum to avoid hindering the function of the aortic valve and the left ventricular outflow tract. |
US10945841B2 |
Valve prosthesis and method for delivery
Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion. |
US10945840B2 |
System and method of stepped deployment of prosthetic heart valve
A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure. |
US10945837B2 |
Apparatus and methods for implanting a replacement heart valve
Systems and methods for docking a heart valve prosthesis. A system can include an anchor formed as multiple coils adapted to support a heart valve prosthesis with coil portions positioned above and below the heart valve annulus. At least one of the coil portions can normally be at a first diameter and be expandable to a second, larger diameter upon application of radial outward force from within the helical anchor. Methods can include delivering an anchor, positioning and implanting a heart valve prosthesis, and expanding the heart valve prosthesis inside the anchor. |
US10945833B2 |
Accommodative intraocular lens
IOL of the type which include a lens, haptics and a curving ring wherein there are soft haptics and rigid haptics, both being associated through a lever and wherein a softer outer ring houses in its inner geometry an inner curving ring, the latter being rigid and incomplete, with curving flaps in whose geometry the assembly consisting of lens and haptics is housed. |
US10945826B2 |
Endoluminal prosthetic assemblies, and associated systems and methods for percutaneous repair of a vascular tissue defect
A prosthetic assembly for repairing a target tissue defect within a target vessel region configured includes an exclusion structure sized to substantially bypass target tissue defect, and includes a branch assembly. The branch assembly can include a self-expanding outer branch prosthesis having an inflow region configured to deform to a non-circular cross-sectional-shape when deployed, and a support structure at least partially disposed within the inflow region. The support structure preserves blood flow to the branch vessel while the deformed inflow region inhibits blood leakage between and/or around the prosthetic assembly. |
US10945825B2 |
Aneurysm stop pressure system
Intravascular devices and systems useful for blocking the opening of an aneurysm or a vessel branch are disclosed. In some aspects, the disclosure provides arrangements that align a covering material of a stent graft with an opening in the vessel wall before, during, and/or after expansion of the stent graft within the vasculature of a patient. In some instances, systems and devices include a sheath with a side aperture arranged to align a portion of the sheath and/or a portion of a stent graft contained within the sheath with the mouth of an aneurysm. Similarly, the present disclosure also provides embodiments in which the stent graft comprises an aligning member arranged to align the stent graft and/or a sheath with the mouth of an aneurysm. Other embodiments are disclosed. |
US10945821B2 |
Sintered blank for producing a dental prosthesis
A sintered blank (1) for producing a dental prosthesis is provided, in which the sintered blank (1) include at least one product area (2), from which the dental prosthesis is produced, and at least one auxiliary sintering body (3) and connecting webs (4) for bracing the product area (2), wherein the auxiliary sintering body (3) is connected to the product area (2) by the connecting webs (4), the auxiliary sintering body (3) including one, preferably precisely one, at least in some areas, preferably completely curved support surface (5). |
US10945820B2 |
Production of a dental prosthesis
Method for manufacturing a dental prosthesis on implant, characterized in that it comprises a step of manufacturing of the outer wall (E5) of the dental prosthesis and a step of manufacturing of at least one connection (E6) intended for fixing on to at least one implant. |
US10945819B2 |
Pluggable implant
A pluggable implant is disclosed that is comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end, the cavity capable of accommodating a plug insertable from the distal end towards the apical end, such that when the plug is fully inserted and located in its apically-most position, the plug seals the cavity. Moreover, there is a method for plugging a hollow implant is disclosed, the implant comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end; wherein a plug is removably inserted into the implant through the cavity from the distal end towards the apical end such that when the plug is in fully inserted position and located in its apically-most position, the plug seals the cavity. |
US10945818B1 |
Dental appliance and method for adjusting and holding the position of a user's jaw to a relaxed position of the jaw
The disclosed dental appliance is a functional daytime and nighttime anatomical removable dental appliance that is designed to overlay the existing natural dentition of the user. In desirable embodiments, the appliance can be held in place without any alterations to the user's existing dentition. The appliance is a plural piece or plural section intra-oral removable appliance with occlusal surface portions that have been built up to occupy the measured intra-occlusal spaces that exist between pairs of upper and lower teeth when the mandible is in a relaxed or rest position. |
US10945817B1 |
Orthodontic appliances and methods of making and using same
A method for altering an orthodontic archwire of a unitary piece of shape memory alloy having a composition and generally uniformly formed properties along its length to different stiffness profiles along the length of the archwire. In one embodiment, the method includes determining a stress profile for teeth at a location. The method may include calculating a force the archwire is to produce on the teeth to satisfy the determined stress profile and determining an altered stiffness of a section of the archwire based on the calculated force. The method may include changing the composition of the section based on the determined altered stiffness. The method may include determining a load for teeth and calculating a force the archwire is to produce on the teeth to satisfy the determined load. |
US10945816B1 |
Orthodontic bracket positioning instrument
The orthodontic bracket positioning instrument is designed to engage an orthodontic bracket for precisely positioning a center of an orthodontic bracket on a center of the crown while maintaining an open visual field of the bracket and relevant structures of the tooth. The positioning instrument includes a key that is configured to mate with a receiving aperture formed in the bracket. A proximal side of the key is supported by a base that extends along a length of the key. An alignment notch is defined within a proximal side of the base to indicate the center of the bracket, as well as the horizontal axis of the bracket. A handle extends from the proximal side of the base. The handle may extend from the base at an angle to provide a clear line of sight to the base, the bracket, and supporting tooth. |
US10945814B2 |
Orthodontic systems and methods
Orthodontic systems and methods involving segmentary shells are disclosed. Examples of the systems and methods are particularly focused on applying a distalization force to a segment of teeth in a posterior lateral sector. |
US10945813B2 |
Providing a simulated outcome of dental treatment on a patient
Systems and methods of simulating dental treatments are disclosed. A method may include capturing a first 2D image of a patient's face, including the patient's teeth, building a parametric 3D model of the patient's teeth based on the 2D image, developing a simulated outcome of a dental treatment of the patient's teeth by rendering the 3D model with the patient's teeth in one or more positions and/or orientations corresponding to the treatment goals of the dental treatment plan, and rendering a second 2D image of the patient's face with teeth according to a simulated outcome of the dental treatment plan. As noted herein, the dental treatment plan may include orthodontic and/or restorative elements. The simulated outcome may correspond to estimated outcomes and/or intended outcomes of the dental treatment plan. |
US10945808B2 |
Cleaning systems for reprocessing surgical instruments
A cleaning fixture for a surgical instrument includes a handle receiving portion configured to receive a housing of a surgical instrument, a shaft receiving portion configured to receive a shaft and an end effector assembly of the surgical instrument, and a knife actuation assembly movably coupled to the handle receiving portion or the shaft receiving portion. The shaft receiving portion extends distally of the handle receiving portion. The knife actuation assembly is configured to selectively actuate a knife trigger assembly of the surgical instrument to advance a knife of the surgical instrument between jaw members of the end effector assembly thereof. |
US10945803B2 |
Cable, wire and tube organizer for laparoscopic and hysteroscopic surgery
An organizing device for use during medical procedures is disclosed which, when used during laparoscopic or hysteroscopic surgery, enables the surgeon to keep multiple tubes, wires and cables organized. In a first embodiment, this device may have a rectangular shaped body, a top section with an integral ring at its center and a bottom section having a plurality of slots optimized for the insertion and retention of cables and tubes. The end sections contain, on one end a second integral ring, and on another a pivot point allowing a friction-closure latch mechanism to secure the slots. In a second embodiment, the device may have a donut shaped body, an integral ring at the center and a plurality of slots radially arranged at the periphery and secured through a cylindrical latching mechanism. In a third embodiment, the device may be secured using magnets instead of a pivoting latch mechanism. |