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US10844156B2 |
Cross-linked polymeric resin and methods of use
A method for producing a cross-linked polymeric resin, whereby (i) a phenol compound, or an oligomer or polymer thereof, (ii) a diol, or an oligomer or polymer thereof, (iii) an aldehyde, (iv) an acid, and (v) an organic solvent are mixed together to produce a reaction mixture, the reaction mixture is heated at 70-200° C. to produce a precipitate, and the precipitate is washed and dried to form the cross-linked polymeric resin, wherein the phenol compound is of formula I: and wherein the diol is of formula II: wherein R1, R2, R4 and R5 are independently H, an optionally substituted alkyl, an optionally substituted cycloalkyl, or an optionally substituted aryl; X is absent, HC═CH, or C≡C; and n=1, 2, 3, 4, 5, or 6. |
US10844150B2 |
Mixed catalysts with 2,6-bis(imino)pyridyl iron complexes and bridged hafnocenes
The present invention provides a supported catalyst system comprising: a bridged group 4 metallocene compound, an iron compound, specifically a 2,6-bis(imino)pyridyl iron complex, a support material and an activator. The present invention further provides a process for polymerization of monomers (such as olefin monomers) comprising contacting one or more monomers with the above supported catalyst systems. |
US10844147B2 |
Multiple reactor and multiple zone polyolefin polymerization
Apparatuses and processes that produce multimodal polyolefins, and in particular, polyethylene resins, are disclosed herein. This is accomplished by using two reactors in series, where one of the reactors is a multi-zone circulating reactor that can circulate polyolefin particles through two polymerization zones optionally having two different flow regimes so that the final multimodal polyolefin has improved product properties and improved product homogeneity. |
US10844146B2 |
Ethylene-based polymers formed by high pressure free radical polymerizations
A process to form an ethylene-based polymer, as described herein, in a tubular reactor system comprising at least three ethylene-based feeds, and at least four reaction zones, and where the weight ratio of “the ethylene-based feed to the second zone (EBF2)” to “the ethylene-based feed to the first zone (EBF1),” is from 0.50 to 1.10; and the weight ratio of “the ethylene-based feed to the third zone (EBF3)” to “the ethylene-based feed to the first zone (EBF1),” is from 0.40 to 2.50; in each zone, the polymerization takes place at a start temperature≥135° C.; and (a) for three or more ethylene based feeds, the peak temperatures in the first and the second zones, are each from 200° C. to 250° C.; and/or (b) for four or more ethylene based feeds, the peak temperatures in the first, the second and the third zones, are each from 200° C. to 250° C.; and the differential in peak temperatures of the first three zones (TP1, TP2, TP3) meets at least one relationship described herein. |
US10844145B2 |
Method for producing an electrode material
The present invention relates to a process for polymerization, wherein the monomers are used in the form of solid particles in an aqueous phase. The polymers obtained thereby can be oxidized further to polymers which can be used as electrical charge storage means, especially secondary batteries. |
US10844141B2 |
Process for obtaining polysaccharides from jatoba (Hymenea courbaril l ) seeds, cosmetic composition comprising said polysaccharides and uses thereof
The present invention relates to a process for obtaining polysaccharides from jatoba seeds, comprising the steps of: a) seed processing (dry process); b) aqueous extraction at 1% to 5% of powder mass per volume, preferably 2% of powder mass per volume; c) precipitation with ethanol 969GL using 1 to 3 times the aqueous extract volume; d) press filtration of the precipitate obtained in (c); e) solublization of the polysaccharides obtained in step (d) with water; and f) drying the polysaccharides obtained in step (e). In another embodiment, the present invention relates to a cosmetic composition containing polysaccharides obtained according to the process defined above and to the use of said polysaccharides. |
US10844140B2 |
Phosphonated polysaccharides and gels and process for making same
Products and processes that are related to phosphonated polysaccharide compositions, including phosphonated polysaccharide gels, having a substituent degree of substitution with a lower limit of 0.02 and an upper limit of 3, and having a weight average molecular weight with an upper limit of 5,000,000 g/mole, as well as to oil field application or fracturing fluid compositions comprising such phosphonated polysaccharide compositions. |
US10844139B2 |
Carbohydrate composition and process for making a carbohydrate composition
The invention relates to a carbohydrate composition characterized in that it has a dextrose equivalence of from 20 to 25 and further characterized in that it has a fibre content of from 10 to 90% by weight of the composition on dry basis. The invention further relates to a process for making a carbohydrate composition. Further the invention relates to a food, feed, pet food, pharmaceutical, cosmetic and industrial products comprising the carbohydrate composition of the present invention and other ingredients and to the use of the carbohydrate composition of the present invention. |
US10844137B2 |
Anti-CTLA-4 antibodies and uses thereof
The present invention provides antibodies that bind to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and methods of use. In various embodiments of the invention, the antibodies are fully human antibodies that specifically bind to CTLA-4. In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing CTLA-4 activity, thus providing a means of activating T-cells and/or for treating a disease or disorder such as cancer or viral infection. |
US10844135B2 |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates and methods of making said
The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a non-cleavable linker and the cell-binding agent binds to cells of the selected cell population. |
US10844133B2 |
Cancer therapy using CLDN6 target-directed antibodies in vivo
The invention relates to the treatment and/or prevention of tumor diseases associated with cells expressing CLDN6, in particular cancer and cancer metastasis using antibodies which bind to CLDN6. The present application demonstrates that the binding of antibodies to CLDN6 on the surface of tumor cells is sufficient to inhibit growth of the tumor and to prolong survival and extend the lifespan of tumor patients. Furthermore, binding of antibodies to CLDN6 is efficient in inhibiting growth of CLDN6 positive germ cell tumors such as teratocarcinomas or embryonal carcinomas, in particular germ cell tumors of the testis. |
US10844126B2 |
Anti-galectin-1 (GAL1) monoclonal antibodies and fragments thereof for neutralizing GAL1
The present invention is based, in part, on the discovery of galectin 1 (Gal1) epitopes against which anti-Gal1 agents can neutralize Gal1 function, as well as anti-Gal1 agents and methods useful for neutralizing Gal1 function. |
US10844122B2 |
Prostate specific membrane antigen (PSMA) bispecific binding agents and uses thereof
Provided herein are isolated CD3×PSMA-bispecific antigen-binding molecules or bispecific antigen-binding fragment thereof wherein a FN3 domain specifically binds human prostate specific membrane antigen (PSMA) and a second antigen-binding site immunospecifically binds CD3. Also described are fusion proteins and related polynucleotides capable of encoding the provided fusion proteins and, cells expressing the provided fusion proteins. In addition, methods of using the provided isolated CD3×PSMA-bispecific antigen-binding molecules or bispecific antigen-binding fragment thereof are described. |
US10844119B2 |
Anti-LAG-3 antibodies and methods of use thereof
The instant disclosure provides antibodies that specifically bind to LAG-3 (e.g., human LAG-3) and antagonize LAG-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies. |
US10844118B2 |
Treatment of inflammatory skin disease
The methods, compositions, and assays described herein are based, in part, on the discovery that CD1a mediates inflammation related to certain conditions such as urushiol exposure, psoriasis and other inflammatory skin diseases. One aspect provided herein relates to a method for treating or preventing an inflammatory skin disease, the method comprising: administering a therapeutically effective amount of an inhibitor of CD 1a to a subject having an inflammatory skin disease, thereby treating or preventing the inflammatory skin diseases. |
US10844117B2 |
Human alpha-folate receptor chimeric antigen receptor
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα) binding domain and CD27 costimulatory domain to treat ovarian cancer. In an embodiment, the FRα binding domain is fully human, thereby preventing a host immune response. |
US10844116B2 |
Use of anti-pacap antibodies and antigen binding fragments thereof for treatment, prevention, or inhibition of photophobia
This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof. |
US10844114B2 |
Anti-Pseudomonas Psl binding molecules and uses thereof
This disclosure relates to an anti-Pseudomonas Psl binding molecule and uses thereof, in particular in prevention and treatment of Pseudomonas infection. Furthermore, the disclosure provides compositions and methods for preventing and treating Pseudomonas infection. |
US10844109B2 |
Method for producing erythrocyte proteins
The invention relates to a novel method for the synthesis of an erythrocyte protein, in which said protein is synthesized in an acellular system for the production of proteins, in the presence of at least one detergent which is non-ionic, of liposomes or of nanodiscs. The invention also relates to compositions comprising the proteins produced in this way. |
US10844106B2 |
Fusion proteins comprising an engineered knottin peptide and uses thereof
The present disclosure presents a general approach to engineering existing protein-protein interactions through domain addition and evolution. The disclosure teaches the creation of novel fusion proteins that include knottin peptides where a portion of the knottin peptide is replaced with a sequence that has been created for binding to a particular target. Such fusion proteins can also be bispecific or multi specific in that they can bind to and/or inhibit two or more receptors or receptor ligands. Knottins may be fused with an existing ligand (or receptor) as a general platform for increasing the affinity of a ligand-receptor interaction or for creating a multi specific protein. In addition, the fusion proteins may comprise a knottin peptide fused to another protein where the other protein facilitates proper expression and folding of the knottin. |
US10844097B2 |
Engineered influenza antigenic polypeptides and immunogenic compositions thereof
The present invention provides, among other things, a novel and improved method for generating “mosaic” influenza antigenic polypeptides including hemagglutinin (HA) and neuraminidase (NA) polypeptides based on unique combination of epitope patterns that maximize exposure to epitopes present across multiple HA or NA sequences and therefore improved influenza strain coverage. In particular, the present invention provides engineered influenza B hemagglutinin (HA) polypeptides that are comprised of novel combinations of protective epitopes and antigenic regions from multiple influenza B viral strains. Such engineered HA polypeptides have improved properties over HA polypeptides developed through conventional approaches that rely on consensus alignments of viral sequences. |
US10844094B2 |
Biosynthetic proline/alanine random coil polypeptides and their uses
The present invention relates to a biosynthetic random coil polypeptide or a biosynthetic random coil polypeptide segment or biosynthetic conjugate, in which the biosynthetic random coil polypeptide, the biosynthetic random coil polypeptide segment, or the biosynthetic conjugate comprises an amino acid sequence consisting solely of proline and alanine amino acid residues, wherein the amino acid sequence consists of at least about 50 proline (Pro) and alanine (Ala) amino acid residues. The at least about 50 proline (Pro) and alanine (Ala) amino acid residues may be (a) fconstituent(s) of a heterologous polypeptide or an heterologous polypeptide construct. Also uses and methods of use of these biosynthetic random coil polypeptides or polypeptide segments or conjugates are described. |
US10844092B2 |
Peptide for promoting regeneration of dentin or dental pulp tissue
Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide. |
US10844091B2 |
Peptide with antidepressant activity and therapeutic effect against Alzheimer's disease
The invention includes a tetrapeptide to be used in the treatment of Alzheimer's disease and depression. The tetrapeptide comprises the general formula, acetyl-X-ARG-ARG-amide, where X=-(D-ARG)-ARG-; -(D-LYS)-LYS-; or -(D-MET)-MET-. On the basis of the combination of pharmacological properties identified, a preparation including the tetrapeptide has potential for clinical use as a nootropic, neuroprotective, and antidepressant agent. |
US10844089B2 |
Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
The sulfated oxysterol 5-cholesten-3β, 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided. |
US10844086B2 |
Method for producing halogen-crosslinked iridium dimer
A method for producing a halogen-crosslinked iridium dimer with increased purity that is used as a precursor in production of a cyclometalated iridium complex useful as a phosphorescent material for organic electroluminescent devices, organic electrochemiluminescent devices, luminescent sensors, photosensitizing pigments, photocatalysts, luminescent probes, various light sources, and the like. The halogen-crosslinked iridium dimer is represented by the following formula: In this formula, each X represents a halogen atom, each CyA represents an optionally substituted five- or six-membered cyclic ring containing nitrogen atoms, and is linked to iridium via the nitrogen atoms, and each CyB represents an optionally substituted five- or six-membered ring containing carbon atoms, and is linked to iridium via the carbon atoms. CyA and CyB can be linked together to form an optionally substituted ring. |
US10844085B2 |
Organic electroluminescent materials and devices
A compound having the formula [LA]3-nIr[LB]n is disclosed. In the formula, LA is and LB is Formula I. |
US10844084B2 |
Organic electroluminescent materials and devices
A compound including a first ligand LA having the formula: is disclosed. |
US10844081B2 |
Protected organoboronic acids with tunable reactivity, and methods of use thereof
Disclosed are a range of protected organoboronic acid reagents useful in the modular assembly of complex organic compounds. The reactivities of the protected organoboronic acid reagents may be varied predictably by changes to the number and identities of their substituents. Also disclosed are methods of using the protected organoboronic acid reagents in the synthesis of organic compounds. |
US10844080B2 |
Compositions and methods for inhibiting arginase activity
The invention relates to a novel class of compounds that exhibit activity inhibitory activity toward arginase, and pharmaceutical compositions comprising the compounds of the invention. Also provided herein are methods of treating cancer with the arginase inhibitors of the invention. |
US10844077B2 |
Thiazolyl-containing compounds for treating proliferative diseases
The present disclosure provides thiazolyl-containing compounds of Formula (I), (II), or (III). The compounds described herein may be able to inhibit protein kinases (e.g. Src family kinases (e.g. hemopoietic cell kinase (HCK)), Bruton's tyrosine kinase (BTK)) and may be useful in treating and/or preventing proliferative diseases (e.g. myelodysplasia, leukemia, lymphoma, (e.g. Waldenström's macroglobulinemia)) and in inducing apoptosis in a cell (e.g. malignant blood cell). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein. |
US10844076B2 |
Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art. |
US10844074B2 |
Heterocycle compounds and uses thereof
Compounds having the general formula (I) and pharmaceutical compositions that can be used as Bruton's Tyrosine Kinase (BTK), ITK, JAK3, and selective mutant epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitor and their uses in the treatment of related diseases and disorders such as cancer. |
US10844070B2 |
Peripherally restricted GABA positive allosteric modulators for the treatment of irritable bowel syndrome and other ailments of the peripheral nervous system
The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance. |
US10844068B2 |
Compounds and compositions as toll-like receptor 7 agonists
The invention provides compounds of Formula (I), immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat diseases or disorders associated with Toll-Like Receptor 7 activity. |
US10844066B2 |
2-amino-N-[7-methoxy-2, 3-dihydroimidazo-[1,2-c] quinazolin-5-yl] pyrimidine-5-carboxamides
This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. |
US10844065B2 |
Heterocyclic compound, and organic electroluminescence device and organic electroluminescence display device including the same
Provided are a heterocyclic compound represented by Formula 1 and an organic electroluminescence device and an organic electroluminescence display device including the heterocyclic compound represented by Formula 1 in an emission layer. In Formula 1, A is represented by Formula 2, D1 is represented by Formula 3, and D2 is represented by Formula 4. |
US10844062B2 |
Pyridine derivative inhibiting RAF kinase and vascular endothelial growth factor receptor, method for preparing same, pharmaceutical composition containing same, and use thereof
The present invention provides a novel pyridine derivative, a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient. The pyridine derivative according to the present invention inhibits Raf kinase (B-Raf, Raf-1, or B-RafV600E) and a vascular endothelial growth factor receptor (VEGFR2) involved in angiogenesis, and thus, can be favorably used for the prevention or treatment of melanoma, colorectal cancer, prostate cancer, thyroid cancer, lung cancer, pancreatic cancer, ovarian cancer, or the like, which is induced by RAS mutation. |
US10844054B2 |
Compounds for pain treatment, compositions comprising same, and methods of using same
The invention relates to compounds of formula (I), compositions containing the same, and methods for treating and/or diminishing pain in a subject. The compounds of formula (I) are effective for treating opioid-induced tachyphylaxis and opioid-induced hyperalgesia. |
US10844050B2 |
Cyclization processes of hydroxyalkenoic acids and products thereof
The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI). |
US10844046B2 |
Imidazolyl-substituted indole derivatives binding 5-HT7 serotonin receptor and pharmaceutical compositions thereof
The invention relates to a new class of substituted indole derivatives that are able to activate 5-HT7 serotonin receptor. These compounds bind 5-HT7 serotonin receptor with high affinity and selectivity, while possessing favourable physicochemical properties. The compounds of the invention are the first described low-basicity 5-HT7 receptor agonists. The invention also relates to use of such compounds in the treatment or prevention of 5-HT7 receptor-related disorders, especially of the central nervous system. The invention also relates to the isotopically labelled compounds for use in the in vivo diagnostics or imaging of a 5-HT7 serotonin receptor. |
US10844044B2 |
WDR5 inhibitors and modulators
Described are imino-azacycle-benzamide compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject. |
US10844041B2 |
Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention. |
US10844038B2 |
1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions
This invention provides compounds of the formula (I): wherein Y1, Y2, Z, X1, X2, and W′ are defined in the specification. These compounds are useful in the treatment of tyrosine kinases, MAPK signaling pathway kinases and PI3K/AKT/mTor signaling pathway kinases-mediated diseases or conditions, such as neurodegeneration, neuroprotection, cancer, autoimmune as well as other diseases and conditions associated with the modulation of tyrosine kinases selected from FYN, FYN Y531F, FLT3, FLT3-ITD, BRK, ITK, FRK, BTK, BMX, SRC, FGR, YES1, LCK, HCK, RET, CSK, LYN, and ROS1; MAPK pathway kinases selected from ARAF, BRAF, CRAF, ERK1/2, MEK1, MEK2, MEK3, MEK4, MEK5, MEK6, and MEK7; and PI3K/AKT/mTor pathway kinases: selected from mTor, PI3K α, PI3K β, PI3K γ, and PI3K δ. |
US10844034B2 |
Nonionic surfactant
A nonionic surfactant that is environmentally friendly, has excellent surface active power (emulsifying power and solubilizing power), and is capable of stably maintaining the excellent surface active power for a long time is provided. A nonionic surfactant of the present invention contains polyglycerol monoether represented by the formula (1), wherein a ring Z represents a condensed ring of an aromatic hydrocarbon ring having 6 to 14 carbon atoms and a 3 to 6-membered heterocycle containing an oxygen atom as a heteroatom; R1 is a substituent bonded to the ring Z and represents an aliphatic hydrocarbon group having 14 to 25 carbon atoms; the ring Z optionally has one or more substituents other than R1; and n is an average number of monomers of glycerol and represents 2 to 20. |
US10844030B2 |
Method for producing furfural
The present invention relates to a method for producing furfural, including: obtaining a sugar solution containing at least one of a monosaccharide having 5 carbon atoms and a polysaccharide containing the monosaccharide having 5 carbon atoms by carrying out a reaction with a specific resource as a raw material in the presence of a catalyst in a solvent; converting at least one of the monosaccharide and the polysaccharide containing the monosaccharide in the sugar solution into furfural by a dehydration reaction, so as to obtain a reaction solution; and separating the reaction solution into an organic layer and an aqueous layer, wherein an aromatic hydrocarbon solvent having a density of from 0.90 g/cm3 to 1.1 g/cm3 at 25° C. and under atmospheric pressure is used, and wherein the reaction solution is separated at a temperature higher than 90° C. and lower than 150° C. |
US10844029B2 |
Phenyl-piperazine derivatives as serotonin reuptake inhibitors
The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder. |
US10844027B2 |
Carboxylic diarylthiazepineamines as mu-opioid receptor agonists
The present invention provides a compound having the structure of the instant invention of a pharmaceutically acceptable salt or ester thereof, methods of preparing the same, and methods of treating a subject with compounds of the instant invention in combination therapies. |
US10844024B1 |
Method for producing thiocarboxamidine salt compound
The present disclosure provides an industrially preferable, economical, and environmentally friendly method for producing a compound [C1] of formula (5), namely, a (4,5-dihydroisoxazol-3-yl)thiocarboxamidine salt compound. The present disclosure relates to a method wherein: a reaction expressed by reaction formula [C2] is caused so as to produce a compound of formula (4) by reacting a compound of formula (3) with a halogenation agent in the presence of a nitrile solvent, and the compound of formula (4) is subsequently reacted with an isothiouronium-forming agent, thereby producing a compound of formula (5). |
US10844022B1 |
Pharmaceutical composition and method of treating cancer
Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin. |
US10844018B2 |
Pyridoxine derivative for treatment of epilepsy
A pyridoxine-based compound of formula 1: exhibits a high level of antiepileptic activity. At doses of 25, 50 and 100 mg/kg, compound 1 completely suppresses the epileptic electrical activity of the brain within an hour after intraperitoneal administration to rats on the penicillin model of epilepsy. The rats' corazol model of epilepsy shows a decrease in intensity and duration of seizures with the administration of compound 1 at doses of 25 and 100 mg/kg intraperitoneally and 100 and 200 mg/kg orally, and the complete prevention of seizures in some cases at a dosage of 250 mg/kg with oral administration. Compound 1 is low toxic. The LD50 parameter in rats exceeds 2000 and 5000 mg/kg of body weight with intraperitoneal and oral administration respectively. The technical solution provides a new highly effective and safe drug for the treatment of epilepsy. |
US10844012B2 |
Antibacterial compounds and methods of use thereof
Disclosed herein are antibacterial compounds, pharmaceutical compositions including the antibacterial compounds, and methods of treating bacterial infections using the compounds and compositions. |
US10844011B2 |
Process for producing pyrrole compound
The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction. |
US10844010B2 |
Process for producing (poly)sulfide compound and process for producing episulfide compound
In a process for producing a (poly) sulfide compound represented by General Formula (2) of the present invention, thiol compounds represented by General Formula (1) are reacted with each other in the presence of a basic compound represented by General Formula (4) or General Formula (5) and sulfur. |
US10844006B2 |
Trisamide compounds and compositions comprising the same
Provided are trisamide compounds and compositions containing the same. In an embodiment, the trisamides are represented by the following formula: wherein R1 represents a univalent group other than hydrogen, and X1 and X2 represent independently selected univalent groups. |
US10844001B2 |
Process to prepare higher ethylene amines and ethylene amine derivatives
The present invention relates to a process to prepare ethylene amines of the formula NH2—(C2H4—NH—)pH wherein p is at least 3 or derivatives thereof wherein one or more units —NH—C2H4—NH— may be present as a cyclic ethylene urea unit or between two units —NH—C2H4—NH— a carbonyl moiety is present, by reacting an ethanolamine-functional compound, an amine-functional compound in the presence of a carbon oxide delivering agent, wherein the molar ratio of carbon oxide delivering agent to amine-functional compound is at least 0.6 to 1. |
US10843996B2 |
Modulators of liver receptor homologue 1 (LRH-1) and uses
This disclosure relates to modulators of liver receptor homologue 1 (LRH-1) and methods of managing disease and conditions related thereto. In certain embodiments, modulators are derivatives of hexahydropentalene. In certain embodiments, this disclosure relates to methods of treating or preventing cancer, diabetes, or cardiovascular disease by administering an effective amount of a hexahydropentalene derivative disclosed herein. |
US10843995B2 |
Processes for manufacturing aromatic carboxylic acids
A process for manufacturing a carboxylic acid is provided, in one aspect, the process comprises oxidizing a feedstock comprising a substituted aromatic hydrocarbon to form a liquid-phase aromatic carboxylic acid; crystallizing at least a portion of the liquid-phase aromatic carboxylic acid in the presence of oxygen and an oxidation catalyst in a first crystallizer to form solid aromatic carboxylic acid, under reaction conditions suitable to oxidize unreacted feedstock to form additional aromatic carboxylic acid; and crystallizing at least a portion of the first crystallization effluent in the presence of oxygen and an oxidation catalyst in a second crystallizer to form additional solid aromatic carboxylic acid, under reaction conditions suitable to oxidize unreacted feedstock to form additional aromatic carboxylic acid, wherein the oxygen is present in a gaseous phase inside the second crystallizer in an amount of no more than 11% by volume on a dry basis. |
US10843989B2 |
Method for the combined production of methanol and ammonia
Method and system for the combined production of methanol and of ammonia, and method for producing a fuel using methanol, wherein a carbon-containing energy carrier flow and an oxygen flow from an oxygen-producing assembly are fed to a synthesis gas reactor assembly for obtaining a synthesis gas flow with hydrogen and carbon oxides, wherein the synthesis gas flow is fed to a methanol reactor assembly for the partial conversion into methanol, and wherein, from the methanol reactor assembly, a residual gas flow is obtained from which a hydrogen-containing flow is obtained, which is at least partially fed to an ammonia reactor assembly and at least partially converted into ammonia there. In an enrichment step, the molar fraction of hydrogen in the synthesis gas flow obtained from the synthesis gas reactor assembly is increased relative to the molar fraction of carbon oxides prior to the feeding to the methanol reactor assembly. |
US10843979B2 |
Method of manufacturing multi-layered propellant grains
A method of manufacturing a multi-layered propellant grain is provided. The method of the present disclosure simplifies the setup necessary to produce multi-layered propellants by using industrial equipment that is more energy and space efficient than the machinery that is conventionally employed for such processes. The method comprises providing a first propellant formulation; providing a die configured to provide a structure having an outer shell and a hollow interior when material is extruded therethrough; extruding the first propellant formulation through said die, to produce a first propellant layer having an outer shell defining a hollow interior in the form channel having open ends; providing a second propellant formulation, said second propellant formulation being of low viscosity; injecting said second propellant formulation into said channel defined by said first propellant layer to form a second propellant layer disposed in said channel; and hardening said second propellant layer. The first and second propellant layers have different rates of burning. |
US10843978B1 |
Materials and methods for agricultural use
Described herein are biofertilizer compositions that rely on a natural oil extract of Tea Tree (Melaleuca alternifolia) (TTO) where the macronutrient components in the composition contribute to the fertilizer mixture, particularly as a foliar fertilizer mixture. The compositions include both TTO macronutrients (NPK) and terpenes. |
US10843976B2 |
Method of producing nanoconcrete with high-energy mixing
In a method of producing nanoconcrete according the bottom-up approach of nano technology with the High-Energy Mixing of composition including cement, water, sand, additives and superplasticizers, the mixing is performed with flow of mixture characterized by Reynolds number and Power number in the range of 20-800 and 0.1-4.0 respectively with installation a disk horizontally into mixing assembly on the top layer of activated mixture coaxially with vertical axis of assembly and with the axis of impeller rotation on the adjustable level to avoid destroying created gel as a result of interruptions of process, to increase laminarity of the mixture flow, energy absorption by the mixture, and shear stress for creation additional quantity of the nanostructured Calcium Silicate Hydrate (C-S-H) gel necessary for making nanoconcrete. |
US10843974B2 |
Radiofrequency component incorporating temperature compensated dielectric material
Disclosed are embodiments of tungsten bronze crystal structures that can have both a high dielectric constant and low temperature coefficient, making them advantageous for applications that experience temperature changes and gradients. In particular, tantalum can be substituted into the crystal structure to improve properties. Embodiments of the material can be useful for radiofrequency applications such as resonators and antennas. |
US10843973B2 |
Inorganic fibre compositions
A sol is provided for the production of inorganic fibres comprising precursors for aluminium oxide, silicon oxide, strontium oxide, wherein the precursors are present in proportions suitable to yield inorganic fibres having a composition comprising: —70≤Al2O3≤80 wt %; 10≤SiO2≤20 wt %; 10≤SrO≤20 wt % wherein the sum of Al2O3, SiO2 and SrO is at least 95 wt %. |
US10843970B2 |
Thermally insulating materials including spherical, hollow inorganic particles
The invention concerns thermally insulating materials comprising the aforementioned particles, a process for the preparation of these particles and materials obtained by incorporation of these particles into matrices. The present invention also concerns inorganic spherical and hollow inorganic particles with low apparent density imparting thermal properties to various types of matrices in which they are dispersed. |
US10843964B2 |
Interfacial bonding oxides for glass-ceramic-to-metal seals
The present invention relates to structure including an interfacial seal between a glass-ceramic component and a metal component, as well as methods for forming such structures. In particular embodiments, the interfacial seal includes a metal oxide. Such interfacial seals can be beneficial for, e.g., hermetic seals between a glass-ceramic component and a metal component. |
US10843961B2 |
IG window unit including laminated substrates for preventing bird collisions
This invention relates to an insulating glass (IG) window unit designed to prevent or reduce bird collisions therewith. The IG window unit includes at least first, second and third substrates (e.g., glass substrates). At least one of the substrates supports an ultraviolet (UV) reflecting coating for reflecting UV radiation so that birds are capable of more easily seeing the window, and wherein at least two of the substrates are laminated to one another via a polymer-based laminating film (e.g., of or including PVB, EVA, or SGP) that may have a high UV absoprtion. The UV reflecting coating is preferably patterned so that it is not provided across the entirety of the IG window unit. By making the window more visible to birds, bird collisions and bird deaths can be reduced. The provision of the laminated substrates in the IG window unit is particularly advantageous for bird collision windows, because it can further reduce bird collisions by providing an increased contrast ratio, improve durability, and improve processing. |
US10843959B2 |
Glass compositions and fibers made therefrom
Embodiments of the present invention relate to glass compositions, glass fibers formed from such compositions, and related products. In one embodiment, a glass composition comprises 58-62 weight percent SiO2, 14-17 weight percent Al2O3, 14-17.5 weight percent CaO, and 6-9 weight percent MgO, wherein the amount of Na2O is 0.09 weight percent or less. |
US10843957B2 |
Glass plate and manufacturing method of glass plate
Separation lines are formed in a glass plate having first and second main surfaces by irradiating with laser light. The separation lines are configured of a product line corresponding to an outline of a glass article to be separated from the glass plate; and a release line. The product line includes a first in-plane void array configured of in-plane voids arranged on the first main surface. A maximum distance between centers of the adjacent in-plane voids arranged on the first main surface falls within a range of 1 μm to 10 μm. The release line includes internal void arrays for release line, which are arranged along lines connecting the first and second main surfaces, respectively. A maximum distance between centers of the adjacent points, at which extension lines extended from the internal void arrays for release line cross the first main surface, is greater than 10 μm. |
US10843955B2 |
Non-contact shaping device and method
A non-contact shaping device includes a first fixture including a fixing section structured to alternately blow out and suck in gas. The fixing section may fix, through suction of gas, a glass plate thereon. An optic heat source processing device is selectively set above predetermined portions of the glass plate to heat, in a non-contact manner, and thus soften, in a temperature-controlled manner, the portions for curving and suspending downward along an edge of the fixing section. The curved glass plate is then lifted up through blowing gas from the first fixture. The second fixture selectively covers the curved glass plate and blow gas therefrom to flow, in collaborative combination with the gas blown from the first fixture, around surfaces of the curved glass plate for cooling and fixing a shape of the curved glass plate in a non-contact manner to form a three-dimensional curve-surfaced glass product. |
US10843950B2 |
Piping manifold for pulsating flow
A disclosed piping manifold for providing pulsating flow includes an outer tubular member extending along a longitudinal axis. The outer tubular member includes a plurality of outer radial openings. An inner tubular member is positionable within the outer tubular member and rotatable about the longitudinal axis. The inner tubular member includes a plurality of inner radial openings, an inlet port configured to receive a fluid, and a lumen providing a fluidic pathway between the plurality of inner radial openings and the inlet port. Rotation of the inner tubular member about the longitudinal axis is configured to periodically bring the plurality of inner radial openings in and out of registration with the plurality of outer radial openings to provide a plurality of pulsating flows of the fluid out of the outer radial openings. |
US10843947B2 |
Diaphragm valve with diaphragm seat carrier
A diaphragm valve includes a valve body including a valve cavity and first and second ports, and a valve assembly disposed to seal the valve cavity. The valve assembly includes a valve seat, a seat carrier and a diaphragm, with the valve seat being retained with said seat carrier and disposed to surround the first port and including a flow passage in fluid communication with the first port. The seat carrier includes an annular body having an outer rim and a web that extends radially inward from the outer rim to a central opening, the central opening being aligned with the first port. The web includes a plurality of flow passages separated by lands about said central opening. Each land has a surface area that is less than a cross-sectional area of said second port so as to reduce obstruction of flow when the land overlays the second port. |
US10843945B2 |
Pilot filter for a water treatment system
A pilot filter system for monitoring water quality in a water treatment system is disclosed. The pilot filter system includes: a filter vessel containing a downward-moving bed of filtration media, the filter vessel being fluidly connected to the water treatment system such that sample influent water from the water treatment system flows into the filter vessel and over the bed, wherein the filter vessel has a filtrate outlet port through which some filtrate is discharged; a media recycle conduit fluidly connected to the filter vessel; and a media recycler for circulating a mixture of water and used filtration media through the media recycle conduit to a point upstream of the bed in the filter vessel. |
US10843941B2 |
Phosphate recovery by acid retardation
A method of recovering phosphoric acid from process water includes directing a process water stream having a pH and a first concentration of phosphoric acid and at least one salt into a vessel, contacting the process water stream with a sorption agent in the vessel, the sorption agent adsorbing phosphoric acid from the process water, withdrawing a first effluent including a first concentration of the at least one salt and a second concentration of phosphoric acid from the vessel, and contacting the sorption agent including the phosphoric acid with water, at least a portion of the phosphoric acid desorbing from the ion exchange media into the water to form a second effluent having a third concentration of phosphoric acid. |
US10843938B2 |
Device and method for purifying and recycling shower water
The present invention describes a hybrid device allowing for purification and either recycling of water or discarding of water, wherein said hybrid device comprises a recirculation loop which facilitates recirculation of water within said hybrid device, and also comprises: a filter system comprising at least one filter; at least one water quality sensor, a modified drain, which is adapted to collect the water used and to facilitate the stream of water used towards the recycling loop and filter system, so that water can be purified and recirculated, or towards drainage; a water treatment unit arranged for hygenisation of water; a functionality sensor for the water treatment unit; wherein the hybrid device is arranged so that: it can operate in a recirculation mode providing purification and recirculation of water, until the water passing through said hybrid device is at a maximum level of contaminants; when any of said sensors is indicating the need to do so, and in particular when said at least one water quality sensor indicates that the water is contaminated above said maximum level of contaminants, the same water is redirected from recirculation to drainage and is discarded from the hybrid device. |
US10843937B1 |
Wastewater disinfection system
An apparatus for disinfecting flowing wastewater in a conduit with a liquid disinfectant from a reservoir of liquid disinfectant. A valve assembly is operatively connected to the liquid disinfectant source for selectively dispensing liquid disinfectant from the source. The valve has a movable valve element normally biased to the closed position. There is an actuator connected to the movable valve element which is responsive to at least one of flow or level of wastewater in the conduit to overcome the biasing force and allow the valve member to move the valve from the normally closed position to an open position. |
US10843936B2 |
Polycrystalline metal oxides with enriched grain boundaries
Provided are electrochemically active secondary particles that provide excellent capacity and improved cycle life. The particles are characterized by selectively enriched grain boundaries where the grain boundaries are enriched with Al and Co. The enrichment with Al reduces impedance generation during cycling thereby improving capacity and cycle life. Also provided are methods of forming electrochemically active materials, as well as electrodes and electrochemical cells employing the secondary particles. |
US10843930B1 |
Systems and methods for synthesis of ZSM-22 zeolite
Systems and methods for production of consistently-sized ZSM-22 zeolite catalyst crystals, a method including preparing an aluminate solution; preparing a silica solution; mixing the aluminate solution and the silica solution to form a zeolite-forming solution; heating the zeolite solution with microwave irradiation in a first, a second, a third, and a fourth distinct isothermal stage to produce the consistently-sized ZSM-22 zeolite catalyst crystals within a pre-selected crystal size range using a non-ionic surfactant. |
US10843925B1 |
Plasma processes for producing graphene nanosheets
Provided are plasma processes for producing graphene nanosheets comprising injecting into a thermal zone of a plasma a carbon-containing substance at a velocity of at least 60 m/s standard temperature and pressure STP to nucleate the graphene nanosheets, and quenching the graphene nanosheets with a quench gas of no more than 1000° C. The injecting of the carbon-containing substance may be carried out using a plurality of jets. The graphene nanosheets may have a Raman G/D ratio greater than or equal to 3 and a 2D/G ratio greater than or equal to 0.8, as measured using an incident laser wavelength of 514 nm. The graphene nanosheets may be produced at a rate of at least 80 g/h. The graphene nanosheets can have a polyaromatic hydrocarbon concentration of less than about 0.7% by weight. |
US10843922B2 |
Compact fluid analysis device and method to fabricate
The present disclosure relates to a device for analyzing a fluid sample. In one aspect, the device includes a fluidic substrate that comprises a micro-fluidic component embedded in the fluidic substrate configured to propagate a fluid sample via capillary force through the device and a means for providing a fluid sample connected to the micro-fluidic component. The device also includes a lid attached to the fluidic substrate at least partly covering the fluidic substrate and at least partly closing the micro-fluidic component. The fluidic substrate may be a silicon fluidic substrate and the lid may be a CMOS chip. In another aspect, embodiments of the present disclosure relate to a method for fabricating such a device, and the method may include providing a fluidic substrate, providing a lid, and attaching, through a CMOS compatible bonding process, the fluidic substrate to the lid to close the fluidic substrate at least partly. |
US10843921B2 |
Electrical connection to a micro electro-mechanical system
A MEMS device includes, in part, first and second conductive semiconductor substrates, an insulating material disposed between the semiconductor substrates, a cavity formed in the second semiconductor substrate, and at least first and second drive masses each of which includes a multitude of beams etched from the first semiconductor substrate and is adapted to move in the cavity in response to an applied force. At least a first portion of the first substrate is adapted to move in response to the applied force and causes the at least first and second drive mass to be in electrical communication with the first substrate. The device may further include, in part, a coupling spring disposed between and in electrical communication with the first and second drive masses. The coupling spring is adapted to provide electrical communication between a second portion of the first substrate and the first and second drive masses. |
US10843919B2 |
Microelectromechanical system apparatus with heater
A MEMS apparatus with heater includes central part, periphery part, gap and first connecting part. Central part includes center of mass, heater and first joint. Heater is disposed inside central part. First joint is located on boundary of central part. Displacement of first joint is produced when central part is heated by heater. Periphery part surrounds central part. Gap surrounds central part, and is located between central part and periphery part. First connecting part connects central part and periphery part along first reference line and includes first inner connecting portion and first outer connecting portion. First inner connecting portion is connected to first joint. First outer connecting portion is connected to periphery part. First reference line passes through first joint, and first reference line is not parallel to line connecting center of mass and first joint. |
US10843914B1 |
Pump bottle access device
A bottle access device comprising a body, a central bore extending partway through the body from a first end, and one or more radial bores extending radially from the central bore through the side of the body. The bores may form a path from outside the body, through the radial bores, through the central bore, and out the first end. The device may be inserted through the wall of a plastic bottle, allowing access to product within the bottle via the bores by squeezing the bottle. The body may be threaded and the second end of the body may be pointed, allowing the device to act as a self-tapping screw for insertion into the wall of the bottle. |
US10843908B2 |
Tower crane
The invention relates to a tower crane with a crane tower and a jib mounted thereon as well as a counter-jib, wherein the length of the counter-jib is defined by the number of the counterweights received. |
US10843907B2 |
Hoisting system for installing a wind turbine
A hoisting system for the installation of a wind turbine wherein said hoisting system comprises measures to achieve a load bearing connection to the tower of the wind turbine and comprises measures to move the hoisting system up and down along the tower wherein the hoisting system, when it is fixed to an already installed part of the wind turbine tower with said load bearing connection, is arranged to install or remove any of a tower segment, a nacelle, a generator, a hub, and a blade in one or more combined hoists or in a single hoist. |
US10843906B2 |
Adjusting device for operating machines
An adjusting device for operating machines is equipped with: a control unit; input units connected to the control unit; and a display unit connected to the control unit. The control unit stores the item ID and adjustment value of each of a plurality of adjustment items. Upon receiving a change operation, the control unit changes the adjustment value of a specified adjustment item to a specified value. Upon receiving a change end operation, the control unit displays, on the display unit, the item ID and the adjustment value corresponding to the adjustment item with the adjustment value changed. |
US10843905B2 |
Systems and methods for slung load stabilization
A hoist support system includes a rail assembly having a rail along which a motor assembly is translatable by actuation of a motor of the motor assembly. The motor assembly is adapted to support a hoist and is communicatively coupled to a control system. The control system is adapted to measure motion of a slung load coupled to the hoist and to determine whether and to what extent the slung load is swinging or otherwise unstable. In response to such measurements, the control system transmits control signals to the motor of the motor assembly to change the position of the motor assembly along the rail and attenuate the motion of the slung load. |
US10843900B2 |
Rope for a hoisting device, elevator and use
A hoisting device rope has a width larger than a thickness thereof in a transverse direction of the rope. The rope includes a load-bearing part made of a composite material, the composite material including non-metallic reinforcing fibers, which include carbon fiber or glass fiber, in a polymer matrix. An elevator includes a drive sheave, an elevator car and a rope system for moving the elevator car by means of the drive sheave. The rope system includes at least one rope that has a width that is larger than a thickness thereof in a transverse direction of the rope. The rope includes a load-bearing part made of a composite material. The composite material includes reinforcing fibers in a polymer matrix. |
US10843895B2 |
Method for controlling a passenger transport system based on one or more system control parameters
The invention relates to a method for controlling a passenger transport system, which transport system comprises at least two passenger conveyors, as e.g. escalators or elevators, which transport system comprises a control for the passenger conveyors and for controlling passenger flow in the transport system. The control is connected to a passenger flow determination device for establishing a passenger flow reference value of the actual passenger flow to be expected in the passenger transport system, and which control further comprises a passenger guide system for controlling passenger flow in the transport system, which passenger guide system uses a cost function considering a set of system control parameters as passenger riding time, energy consumption, passenger waiting time, passenger transport capacity, maintenance demand, etc. The control uses a transport model simulating the function of the hardware components of the transport system under consideration of correlated system operating parameters as e.g. number of active passenger conveyors, passenger conveyor speed, still-stand times, door opening times etc. in connection with passenger flow,whereby the passenger flow reference value is input to the transport model and in an optimization process the system operating parameters are optimized under use of the transport model to meet the passenger flow reference value under consideration of at least one significant system control parameter from said set of system control parameters to achieve a best set of system operating parameters. The best set of system operating parameters is applied to the control of the passenger transport system. |
US10843891B2 |
Nanofiber yarn dispenser
A dispenser is described for dispensing nanofiber yarns that includes a housing that defines an inlet, an outlet, and a chamber. A spool, around which is wound a length of nanofiber yarn, is disposed within the chamber defined by the housing. The nanofiber yarn is threaded from the chamber through the outlet and can be dispensed in a controlled way that reduces the likelihood of developing knots within the nanofiber yarn, and which facilitates convenient application of the yarn onto an underlying surface. In some cases, the dispenser can be used to concurrently dispense an adhesive or other polymer along with the nanofiber yarn. |
US10843889B2 |
Stacker hopper with feed interrupt
A sheet stacking system includes a conveyor for carrying sheets from a conveyor intake end to a conveyor discharge end and a hopper at the discharge end for receiving the sheets and guiding them as they fall in a cascade path onto a platform. The hopper has a backstop facing the discharge end of the conveyor and a first accumulator that includes a carrier and a support extending from the carrier through the backstop. The support is configured to rotate from a retracted position to an extended position relative to the backstop, and the carrier is movable linearly and vertically relative to the backstop with the support in the extended position from a raised location with the support outside the cascade path to a lowered location with the support in the cascade path. |
US10843888B2 |
Transporting sheets of print media
Certain examples described herein relate to transporting sheets of print media. In one example, a media transport apparatus has a plurality of media transport sections including a first media transport section and a second media transport section offset from the first media transport section in a media transport direction. The media transport apparatus has a holding section arranged to receive a sheet of print media from the first media transport section. The holding section is moveable to deposit the sheet of print media upon the second media transport section. |
US10843887B2 |
Apparatus for mounting data carriers onto a carrier web
The invention presented and described comprises an apparatus for mounting flat data carriers (1) on a continuous carrier web (2), having a data carrier supply device (3), a data carrier transfer device (4) and a carrier web positioning device (5), wherein the supply device (3) has a drive roller (6), a deflector (7) arranged substantially horizontally spaced apart from the drive roller (6) and at least one carrying belt (8) which runs around the drive roller (6) and deflector (7), wherein the carrying belt (8) has an upper run (9) which runs substantially horizontally in the feed direction of the data carriers (1), and a lower run (10) which runs in the opposite direction below said upper run, wherein the upper run (9) forms a transport path (11) for the data carrier (1) and is hydraulically connected to a suction box (12) which is arranged beneath in such a way that data carriers (1) which are located on the upper run (9) can be drawn by suction onto the carrying belt (8) by negative pressure, wherein the transfer device (4) has a transfer roller (14), which is provided with intake openings (13) on the circumference and which is hydraulically connected to a negative pressure source in such a way that data carriers (1) located on the outer casing of the transfer roller (14) can be drawn by suction onto the outer casing by negative pressure, wherein the transfer roller (14) has an entry region (15) which is adjacent to the suction box (12) of the supply device (3) and an exit region (16), which is spaced apart from the entry region (15) by a specific angle and is adjacent to the positioning device (5), and wherein at the exit region (16) of the transfer roller (14), a data carrier (1) which is located there on the outer casing of the transfer roller (14) can be transferred onto the carrier web (2). |
US10843886B2 |
Friction shaft for slitter
A friction shaft for a slitter has winding tubes disposed on an outer surface thereof to roll unit materials formed by cutting a raw material such as various kinds of paper, fabric, or film with predetermined intervals includes a first rotary shaft, tubes, brake pads, a second rotary shaft, pressing members, first rotary tubes, second rotary tubes, first and second bearings, first elastic members, guide members, second elastic members, and lugs for clamping. |
US10843882B2 |
Automated loading system
Cable robots may be used to automatically load items onto one or more surfaces in any environment. An item may be received on a carrier that is connected to tensioning actuators of a cable robot by one or more cables in tension. The actuators of the robot may be manipulated in concert to move the carrier from a first position to a second position, which may be fixed or in motion, at which the item may be expelled from the carrier. The carrier may include induction wheels and/or conveyors for receiving the item thereon and for expelling the item therefrom. The cable robot may be provided in series with a conveyor and mounted to a frame, and used to load items onto a delivery vehicle, such that the frame may be withdrawn as items are loaded. |
US10843881B2 |
Bulk loader system for thermoplastic pellets
A bulk loader system is disclosed that may include a conveyor unit in connection with a fuel-powered engine powering a hydraulic motor. The hydraulic motor may be used to operate the conveyor unit. The system may be configured to function while being mounted on a bed of a truck or be operated as a stand-alone unit. The unit may be sized such that an operator can stand on the deck of the truck along with the unit. The fuel-hydraulic powered motor can enable the conveyor unit to operate at variable speeds. The conveyor unit can be adjustable to facilitate controlling the direction of the material being transported via the conveyor. Some embodiments can include operating the hydraulics of the motor from the Power Take-Off (“PTO”) of the truck. Some embodiments can facilitate operation of the system in a hot or other harsh environment. |
US10843879B2 |
Load station for a pneumatic transfer system and methods of use thereof
A system and method for a loading station of a pneumatic transfer system is provided. The system and methods comprise structure and functionality to allow for loading of contents and materials to be provided into a loading station or entry point of a system. The system and methods further comprise structure and functionality to limit the risk of overloading a particular input point and ergonomic features to enhance a user experience. |
US10843878B2 |
Article transport facility
The transfer apparatus transfers an article, which is a package, to a container while holding an upper face of the package. A control apparatus performs both a transfer control to cause the transfer apparatus to transfer the article to the container and a first pressing control to cause the pressing apparatus to press, from above, the article that has been transferred to the container through the transfer control if the article to be transferred by the transfer apparatus is a type 1 article, and performs only the transfer control, of the transfer control and the first pressing control, if the article to be transferred by the transfer apparatus is a type 2 article. |
US10843877B2 |
Dishwashing conveyance system and method
A system for grasping and retaining dishware during a cleaning cycle. The system includes a grasping element and a receiving surface substantially adjacent to the grasping element. The grasping element grasps the dishware, and the receiving surface receives and retains the dishware during at least one stage of a cleaning cycle. The receiving surface rotates about an axis to convey the dishware to at least two unique locations. A corresponding method is also described herein. |
US10843874B2 |
Integral pivot/king pin for conveyor
A mobile radial stacker for stockpiling bulk material is provided that includes a stacker frame, a linear conveyor mounted to the frame, the conveyor having a rear portion and a front portion and being designed to carry bulk material from a lower position adjacent the rear portion to a raised position adjacent the front portion, and a pair of wheels mounted to the frame to facilitate movement of the stacker around a work site or to another work site. Also provided is a pivot pad/king pin apparatus mounted to the stacker including an integral king pin and pivot pad that may be displaced from a first position with the king pin facing downward for engagement with a tractor fifth wheel to a second position with the pivot pad facing downward for placement on the ground for radial conveying operations. Another way to describe the depicted embodiments is a pivot pad/king pin apparatus that may be used with a radial stacker. The apparatus may include a body with a king pin and pivot pad integrally mounted into it. The apparatus may be rotatable between a first position with the king pin facing downward for engagement with a tractor fifth wheel to a second position with the pivot pad facing downward for placement on the ground for radial conveying operations. |
US10843871B2 |
Side-by-side slats for a chain conveyor belt and conveyor belt system comprising same
A conveyor belt system provides a continuous flat support surface for a food item that moves the food item through a food preparation device. The conveyor belt system includes a conveyor belt having a plurality of spaced apart rods and a plurality of slats that are removably attached to the conveyor belt with a rod connection mechanism. The slats also include a lateral connection mechanism for lateral removable attachment to an adjacent slat. The slats are easily assembled and provide enhanced field service and/or replacement capability. |
US10843865B2 |
Inner liner for container for consumer articles
A container for consumer goods comprises a package of consumer goods, the package being formed from a sheet blank. The sheet blank comprises a base layer comprising a fibrous cellulosic material; a metal-containing layer provided on an outer side of the base layer; and a first sealable layer comprising a sealable polymeric material provided on at least a seal area of an inner side of the base layer, wherein the first sealable layer is substantially transparent. |
US10843864B2 |
Metallic container dome configured to deform at a predetermined pressure
Methods and apparatus for forming a metallic dome are provided. More specifically, the present invention relates to a metallic dome that may be used to seal an aerosol container. The metallic dome includes a novel flattened relief panel and an inwardly oriented arch configured to deform in response to pressure within the aerosol container exceeding a predetermined amount. In one embodiment, the flattened relief panel is substantially planar. Optionally, the metallic dome includes at least a first inwardly oriented arch with a first radius of curvature and a second inwardly oriented arch with a second radius of curvature. |
US10843863B2 |
Food and beverage cooler assembly
A cooler assembly for the storage of one or more objects includes a cooler portion having a main portion and a cover portion that is removably or pivotable relative to the main portion. First and second main portion securement features are disposed on a side wall of the main portion, and the first and second main portion securement features may be identical. First and second attachment assemblies, which may include a container, have identical first and second attachment securement features, respectively, which may releasably engage either of the first and second main portion securement features to allow the first and second attachment assemblies to be transported with and stored on the cooler portion. |
US10843862B2 |
Ventilated container for produce
A ventilated container for produce includes a bottom, sidewalls extending upwardly from the bottom, and a rim having a flattened top surface. The sidewalls include at least one ventilation opening located proximate the rim of the container thereby permitting the rim of the container to be generally flat and uninterrupted. The location of ventilation opening(s) proximate the rim of the container allows the flow of rising ethylene gas within the container to exit near the top of the container improving ventilation within the container. A plastic film can be applied over the top of the container and is adhered to the container with an adhesive to form a secure and rigid seal between the film and the container. The flattened surface of the rim improves the adherence between a film and the container to enclose and seal the container, aids the rigidity of the container, and lessens the likelihood of the edges of the rim being bent or folded when pressure is exerted to protect produce provided within the container. Moreover, an aperture on the bottom of the container provides drainage of liquid from the container and allow air to flow. |
US10843859B2 |
Hermetic, hygienic, single-use packaging for consumable liquids
In one aspect, a disposable container for hygienic dispensing of a consumable liquid is disclosed. The container comprises a bag made from a flexible, liquid-impermeable material and has a flexible body portion for containing a consumable liquid and a flexible neck portion with a hermetically sealed mouth. The mouth is for dispensing the consumable liquid upon when opened. The neck portion is in a stored position, tucked inside-out inside the body portion. The tucking results in a continuous fold in the bag. The container also comprises a closure for holding together opposite sides of the bag at the continuous fold to maintain the neck portion of the bag in the stored position, tucked inside-out within the body portion, and to shield the neck portion from external contaminants pending opening or removal of the closure and eversion of the neck portion into a dispensing position. |
US10843857B2 |
Packaging container for car floor mats
A packaging container for a car floor mat including: a main body; at least one post member extending from the main body for supporting the car floor mat, and a securing arrangement releasably secured to the post member, the car floor mat being retained on the post member when the securing arrangement is secured to the post member, the car floor mat being removable from the packaging container when the securing arrangement is released from the post member, wherein the securing arrangement includes a catch supported on the main body by a hinged connection, the catch including a ring member for encircling the post member when engaging the post member, the ring member having an inwardly directed engagement member for engaging an overbite provided on the post member when the catch is hinged towards and interlocks with the post member. |
US10843854B2 |
Techniques for making and using holding straps with hook-and-strap attachment
There are provided a holding strap, methods of making the same, and methods using such holding strap for tying down objects on a flatbed of a vehicle, retaining underground tanks, or lifting electrodes out of an electrolytic cell. The holding strap includes a chemically pre-treated strap component, an epoxy resin chemically bonded to the pre-treated strap component, and a hook component comprising a cavity that is configured and sized to receive at least a portion of the strap component, the epoxy resin being chemically bonded to internal surfaces of the cavity, so as to form the holding strap. |
US10843851B2 |
Container for hair tonic
Disclosed is a container for a hair tonic, wherein a nozzle hole (21) is formed at a center inside a lid (20) coupled to an upper portion of a container main body (10), and an assembly hole (31) is formed at a center of a scalp stimulation means (30) coupled to an upper portion of the lid such that a nozzle opening and closing means (40) protrudes above the scalp stimulation means to be operated under pressure while compressing an elastic spring when the scalp is tapped, wherein an inclined portion (21a) having a taper shape outside the nozzle hole is normally in linear contact with an outer edge of a blocking plate (44) at a lower portion of the nozzle opening and closing means for tight sealing, but nozzle opening operation is quickly performed to discharge a medicinal fluid when the nozzle opening and closing means is operated under pressure. |
US10843846B2 |
Container for an aerosol generating device
A container for an aerosol generating device is disclosed. The container has a body has a body comprising a first portion configured to receive an aerosol generating device and one or more retention means externally accessible from the body, each retention means being configured to releasably retain a module. |
US10843832B2 |
Method and device for thermal activation of packaging sleeves
A method and device for thermal activation of tube-shaped packaging sleeves made of cardboard/plastic composite material, wherein a hot gas is applied to the tube-shaped packaging sleeve by a heating device in order to produce the base or the head of the packaging. To achieve even heating for the activation of the contact surfaces with production using simple construction, wherein the energy required for the activation process is used as completely as possible for the heating of the surfaces to be activated, the heating device is placed into effective contact with the surfaces to be activated by the heating device being moved inside the tube-shaped packaging sleeves for activation. The heating device has at least one nozzle element with an outlet opening, the external shape of which nozzle element corresponds to the internal shape of the end of the tube-shaped packaging sleeve to be activated. |
US10843830B1 |
Method for laying multiple conductors in a container
A method for laying multiple conductors in a container may be provided. The method may comprise receiving the multiple conductors at a monitoring station; receiving the multiple conductors at a drive; and receiving the multiple conductors at the container. |
US10843829B2 |
Method for manufacturing a disposable single use applicator assembly with a chemical composition
The applicator assembly delivers a cosmetic, health, or hygiene chemical composition in an active state to the user for a disposable single use. The applicator assembly includes a wrapper, and an insert. The insert holds the chemical composition, and the insert is made of a foam composition compatible with the chemical composition. The system and method for manufacturing the assembly is a web conversion process for the chemical composition and foam composition of the assembly. The system and method for manufacturing the assembly includes a first roll, wrapper material, a second roll, foam material, a foam cutter, a dispenser, a flatbed hot seal packager, a sheet cutter, and an outfeed conveyor. |
US10843824B2 |
Syringe positioning apparatus and method
Syringe positioning apparatus and methods are disclosed that provide for automated positioning of a syringe at an axially aligned position on a predetermined axis. The apparatus and methods employ first and second members having opposing surfaces that include first and second ramps, respectively, wherein the first ramp angles upward and away from the second member, and the second ramp angles upward and away from the first member. At least one of the first and second members may be advanceable toward the other by an actuator, wherein the first and second ramps may slidably engage a syringe and thereby elevate the syringe to the axially aligned position on the predetermined axis. |
US10843823B2 |
Drug packaging unit and drug transfer method for same
A drug packaging unit is disclosed. The drug packaging unit includes a storage portion separately discharging a plurality of units of a drug, a supply portion supplying the drug to a drug packaging member, a detection portion detecting a drug supply error by detecting the drug passing through the supply portion, an adjustment portion adjusting the number of units of drug discharged out of the supply portion, and a driver/controller individually driving the storage portion and the supply portion, thereby putting the drug on standby to be discharged. With this structure, it is possible to reduce a drug packaging time and it is easy to control drug supply. |
US10843818B2 |
Chained flashlight system
A chained flashlight system includes multiple flashlights; multiple lighting control devices that control lighting of the flashlights, respectively; a communication wire; and a traffic control device. The lighting control devices include receiving units, controlling units, and power supply units, respectively and are coupled to the traffic control device by the same communication wire. The traffic control device simultaneously sends a lighting signal to the lighting control devices via the communication wire. The receiving units of the lighting control devices receive the lighting signal. The controlling units of the lighting control devices turn ON the power supply units, respectively, on the basis of the time condition from reception of the lighting signal to turning ON of the power supply units, set for the respective flashlights. The flashlights are lit by turning ON the respective power supply units of the lighting control devices. |
US10843816B2 |
Photographic assembly and unmanned aerial vehicle having same
The present invention relates to the field of aircrafts and provides a photographic assembly applied to an aircraft, where the aircraft includes a vehicle body. The photographic assembly includes: a vibration absorption member, a frame provided at the periphery of the vehicle body and connected to the vehicle body through a vibration absorption member, a gimbal connected to the frame and a camera connected to the gimbal. The frame of the photographic assembly in embodiments of the present invention can be mounted on unmanned aerial vehicle bodies of different specifications and the frame is sleeved over the vehicle body, so that the structure of the vehicle body can be designed compactly. The embodiments of the present invention further provide an unmanned aerial vehicle having the photographic assembly. |
US10843815B2 |
Aircraft wing lighting
An aircraft wing assembly including a wing having a main body 5 and a movable portion 6, so that the wing may be folded when taxiing. A lighting system is provided with a light source 9; a light emitter 11 arranged on one of the main body and the movable portion, and a light guide 10 arranged to transmit light from the light source along a path between the main body and the movable portion to the light emitter. The provision of a light guide between the light source and the emitter allows for light to be transmitted to the emitter across the joint 8 between the wing main body and the movable portion. Thus, lighting on the wing may be provided without the need to provide electrical wiring across the joint. A single light source 9 may be employed to illuminate multiple light emitters 11, 13 on the wing. |
US10843814B2 |
Methods and apparatus for unmanned aerial vehicle landing and launch
An unmanned aerial vehicle (UAV), a stand for launching, landing, testing, refueling and recharging a UAV, and methods for testing, landing and launching the UAV are disclosed. Further, embodiments may include transferring a payload onto or off of the UAV, and loading flight planning and diagnostic maintenance information to the UAV. |
US10843808B2 |
Methods and apparatus for cryogenic fuel bayonet transfers
Methods and apparatus for cryogenic fuel bayonet transfers are disclosed. A disclosed example fuel transfer system includes a fuel tank. The example fuel transfer system also includes a bayonet receptacle extending into an internal volume of the fuel tank, where the bayonet receptacle is to receive a fuel transfer bayonet to fill the fuel tank with fuel and a fuel discharge bayonet to discharge the fuel. |
US10843807B2 |
System and method for aircraft noise mitigation
A system and method for reducing a psychoacoustic penalty of acoustic noise emitted by an aircraft, including a plurality of propulsion assemblies coupled to the aircraft, wherein each of the plurality of propulsion assemblies includes a motor, and a plurality of blades defined by a propeller, wherein the plurality of blades can define an asymmetric blade spacing; a control subsystem coupled to the aircraft and communicatively coupled to the motor of each of the plurality of propulsion assemblies, wherein the control subsystem is operable to rotate each of the plurality of propulsion assemblies at a different frequency to modulate the acoustic power distribution of the emitted acoustic signature. |
US10843806B2 |
Aircraft propulsion assembly with a filtered cradle
An aircraft propulsion assembly includes: a gas generator coupled by a coupling mechanism to a thrust generator having a structural torque transmission gearbox, and a rigid cradle rigidly supporting the thrust generator in a first suspension plane and the gas generator in distinct second and third suspension planes, the cradle being for securing to a structural element of the aircraft via a vibration-filtering flexible connection. |
US10843804B2 |
Cabin outflow air energy optimized cabin pressurizing system
A pressurization system includes a first compressor that receives a ram air, a fan air, or engine air; a first turbine that is on a common shaft with the first compressor and wherein the first turbine receives an engine air; a main heat exchanger downstream of the first compressor and the first turbine; an internal environment suitable for human occupants and downstream of the main heat exchanger; a second turbine downstream of the internal environment; the second turbine may be on the common shaft with the first compressor and first turbine; or a generator downstream of the second turbine; a motor downstream of the generator; and wherein the motor drives the first compressor. |
US10843795B2 |
Folding concentrically mounted propeller blades for drag reduction
A propulsion unit includes a motor rotor, propeller blades, and a pivot stop. The motor rotor spins about a central rotational axis. The propeller blades, including first and second propeller blades, each having a proximal base mounted to the motor rotor such that the propeller blades are rotatable about the central rotational axis. The second propeller blade is pivotally attached to the motor rotor to pivot about the central rotational axis independent of the motor rotor by a limited angle. The pivot stop mechanically limits an amount of pivoting of the second propeller blade relative to the first propeller blade. |
US10843790B2 |
Bistable pitch propeller system with bidirectional propeller rotation
A propeller includes a blade free to rotate. A first stop is positioned to mechanically engage one or both of a first portion of the blade and a first structure coupled to the blade when the blade is in a first position at a first end of the rotational range of motion. A second stop is positioned to mechanically engage one or both of a second portion of the blade and a second structure coupled to the blade when the blade is in a second position at a second end of the defined rotational range. The blade rotates to the first position against the first stop when the propeller is rotated in a first direction and to the second position against the second stop when the propeller is rotated in a second direction. |
US10843787B2 |
Heat shield assembly and mounting thereof on aircraft
Various techniques provide a heat shield assembly and mounting thereof on an aircraft. In one example, a heat shield assembly may include flexible member. The heat shield assembly may further include a plurality of frame members disposed on the flexible member. The heat shield assembly may further include a plurality of mounting structures configured to directly mount the heat shield assembly to a strut of an airplane. Each of the plurality of mounting structures may be disposed on one of the plurality of frame members. Related methods are also provided. |
US10843786B2 |
Reinforcing arrangement for an opening in an aircraft structure
A reinforcing arrangement for an opening in an aircraft fuselage structure has a fuselage skin having an inner side, an outer side and a first opening with a first opening contour, and a one-piece reinforcing structure having a thickening section and at least one projecting profile. The first opening contour is surrounded on the inner side of the fuselage skin by an opening edge surface having a thickness corresponding to a thickness of the fuselage skin surrounding the opening edge surface. The thickening section has a bearing surface matched to the opening edge surface and has a receiving section facing away from the bearing surface and surrounding a second opening. The bearing surface is in surface contact with the opening edge surface, and the reinforcing structure is connected to the fuselage skin, with the result that the first opening and the second opening lie one above the other. |
US10843784B2 |
Hydrogen recycling flight system and flight method
The present invention relates to a hydrogen recycling flight system and flight method, the hydrogen recycling flight system including: a flight fuselage which has at least one pair of wings at each of both sides of a body; a hydrogen gas balloon which is air-tightly connected to the flight fuselage; a hydrogen fuel cell which is connected with the hydrogen gas balloon and is installed outside or inside the flight fuselage; and a secondary battery which is charged with electricity generated from the hydrogen fuel cell, electricity generated from a solar cell provided at an outer peripheral portion of the flight fuselage, or electricity of an external power network, in which by using a switch, the hydrogen fuel cell is switched to a water electrolysis device or the water electrolysis device is switched to the hydrogen fuel cell, the hydrogen recycling flight system includes: a water tank which stores water generated from the hydrogen fuel cell; the water electrolysis device which electrolyzes the stored water; a switch control device which switches functions of the hydrogen fuel cell and the water electrolysis device; and a high-pressure gas barrel which high-pressure stores hydrogen gas and oxygen gas generated in the water electrolysis device, and the flight fuselage flies by controlling the volume of the hydrogen gas balloon that is flotation power of a flight vehicle by an operation of the hydrogen fuel cell or the high-pressure gas barrel. |
US10843783B1 |
Hexakis icosahedron frame-skin vacuum lighter than air vehicle
A vacuum lighter than air vehicle (VLTAV) includes a rigid frame of rods connected together to form a hexakis icosahedron. A membrane skin covers the rigid frame and defines therewith a vessel configured to hold an internal vacuum that allows the vessel to float in the air. The plurality of rods and membrane skin have weights and dimensions that result in a neutral and/or positive buoyancy for the vessel while preventing geometric instability. |
US10843780B2 |
Outboard motor cover
A device and technique for reducing noise experienced by boat passengers from an outboard boat motor is discussed. The device may be implemented in the form of a cover that is adjacent to at least a portion of the boat motor. The cover includes one or more walls or surfaces that reflect or attenuate soundwaves. The cover may be attached to the boat motor and/or the boat. The cover may be integral with the boat motor and/or the boat. The cover may be attached to the boat via a hinge to permit the cover to be pivoted away from the boat motor. The materials used to construct the cover may be provided in layers that help to attenuate, absorb or reflect soundwaves. |
US10843778B1 |
Rudder device for a hydrojet vessel
A rudder device for a hydrojet vessel. The rudder device includes a mounting plate, a primary rudder and a secondary rudder coupled to a hydrojet. The primary rudder and the secondary rudder providing steerage as the hydrojet vessel is displaced through the water. |
US10843777B2 |
Safety release mechanism for kite-surfing
A safety release mechanism for kite surfing with a safety release member by which a kite surfer is attached to the body. A locking element detachably secures an attachment end of the safety release member to the body. A resilient element urges the locking element into the unlocked position, such that upon release for the locking element, the resilient element moves the locking element to the unlocked position thereby resulting in a release of the attachment end of the safety release member, regardless of the orientation of the device, the orientation of the kite, or the available strength of the kite surfer. |
US10843768B2 |
Pump-action ride-along vehicle
A ride-along vehicle may include a guard that attaches to a bottom portion of a molded plastic body and covers a spring and chain assembly. The guard may also provide an attachment point for the spring through a hole in the guard. The guard may have a narrow portion that covers and helps retain the chain on a sprocket as well as a wider portion that covers the spring. An improved pumper arm and steering mechanism may include a pivot joint that is provided by rods, pins, or bolts attached to opposite sides of the pumper arm. The universal joint between the steering arm and the pumper arm can be aligned with the center of the pivot point to prevent rocking of the steering arm as the pumper arm is actuated. |
US10843764B2 |
Control systems and throttle assemblies for vehicles having handlebars
A control system for use by a rider of a vehicle, comprising a handlebar with a grip extending along a grip axis, and a throttle assembly with a housing and mount adapted for attachment to the handlebar along a housing axis arranged coincident to the grip axis and laying in a longitudinal reference plane defining a forward side and a rider side. A thumb trigger is arranged for movement between a first trigger position and a second trigger position, and comprises a thumb pad arranged for engagement by the rider, and a trigger interface supported for rotation about a pivot axis defined by the housing and arranged at an oblique angle relative to the housing axis taken normal to the longitudinal reference plane such that at least a portion of the thumb pad remains on the rider side as the thumb trigger moves between the first and second trigger positions. |
US10843762B2 |
Saddle riding vehicle
A saddle riding vehicle includes: a pair of left and right seat rails disposed below a seat for a passenger; a battery disposed below the seat; and a regulator connected to the battery. In the saddle riding vehicle, when viewed from above, the battery and the regulator are arranged in a longitudinally aligned state between the left and right seat rails, the regulator and the battery are disposed such that the regulator is disposed below an upper surface of the battery in order to form a stepped portion, and an intake duct of an intake device is disposed in a space formed above the regulator by the stepped portion. |
US10843753B2 |
Lever assembly for positive lock adjustable seat post
A method and apparatus for a seat post assembly that is adjustable to an upper, intermediate, and lower seat post position using a locking member and a sleeve member coupled to an actuator for securing and releasing an inner tube with respect to an outer tube. The actuator may move the sleeve member to release the locking member from engagement with the outer tube to adjust the inner tube and thus the seat post assembly to the upper, intermediate, or lower seat post positions. The actuator and the sleeve may be biased into an initial position that urges the locking member into engagement with outer tube to lock the inner tube to the outer tube. |
US10843750B2 |
Endless track for traction of a vehicle
An endless track for traction of an off-road vehicle, such as an agricultural vehicle, an industrial vehicle (e.g., a construction vehicle) or a military vehicle, is provided. The endless track a plurality of elastomeric lugs, such as drive/guide lugs projecting from the inner surface and/or traction lugs projecting from the ground-engaging outer surface. An elastomeric lug may have a material composition defining an arrangement of zones of different materials which comprises a plurality of zones of different elastomeric materials, may exhibit a desired variation of a material property (e.g., across the arrangement of zones of different materials. A zone of the elastomeric lug may have a dedicated function, such as a sacrificial zone or a wear indicator zone. An elastomeric drive lug may comprise an uneven drive surface, such as an angled or curved surface, for engaging a drive member of a drive wheel of the vehicle. |
US10843749B2 |
Straddle mount idler assembly
A straddle mount idler assembly for use with a crawler assembly of a crawler machine. The straddle mount idler assembly includes an idler wheel positioned between inboard and outboard arms of a crawler assembly, the idler wheel fixed both rotationally and axially to an idler shaft. The wheel and shaft are fixed rotationally via locking key and axially via segmented retaining plate and bolts. The axial coupling of the wheel and shaft allows for axial thrust to be controlled outboard the crawler frame for easier access and maintenance. A sealed thrust plate assembly with a dedicated lubrication port is mounted to each bearing block. A retainer nut threadably engages the idler shaft, allowing ready tightening of the retainer when the thrust plate experiences wear, and the retaining nut is fixed to the shaft via a locking bar. A set of integrated inspection ports enable inspection and measurement of the thrust plate without splitting crawler tracks. |
US10843745B2 |
Motor vehicle
A motor vehicle includes a supporting structure, a first component, fastened to the supporting structure, that forms a first part of an outer skin, a second component, fastened to the supporting structure, that forms an adjacent second part of the outer skin, and a setting element positioned in a defined manner relative to the second component and fastened at a gauged position of the first component. |
US10843737B2 |
Method for manufacturing vehicle body member and vehicle body member for vehicle
A method for manufacturing a vehicle body member from a joined sheet. The joined sheet is press formed into a vehicle body member with a predetermined shape by: welding a second sheet material to a first sheet material at a plurality of points including a first joint and a second joint separated from each other; press forming the joined sheet so that a ridge crossing an imaginary line segment connecting the first joint and the second joint is formed in a portion where the first sheet material overlaps the second sheet material; and before the joining step, forming a displacement facilitating portion, which facilitates displacement of the second sheet material relative to the first sheet material in a longitudinal direction of the imaginary line segment, in a portion corresponding to between the first joint and the second joint in the second sheet material. |
US10843734B1 |
Integrated bumper
Provided is an integrated bumper system including, a suspension assembly including, a suspension plate coupled with a robotic device chassis, a plurality of springs positioned along at least a portion of a perimeter of the suspension plate and coupled with the suspension plate, and a plurality of cutouts positioned along at least a portion of the perimeter of the suspension plate; and a bumper coupled with the suspension assembly including, a plurality of spring anchors coupled with the plurality of springs, and a plurality of tabs aligned with the plurality of cutouts configured to limit movement of the suspension plate; and wherein the bumper is configured to move when impacted. |
US10843726B2 |
Method and apparatus for assisting steering of vehicle
In a vehicle, an amount of change of a turning angle of a turning mechanism to an amount of change of a steering angle of a steering input device is defined as a transfer ratio, the turning mechanism is rotationally driven by a turning drive unit, and a driver's body posture parameter is detected by a body posture parameter detector. An apparatus for steering the vehicle includes a controller that executes an automatic steering mode that determines a target value for the turning angle of the turning mechanism based on a travelling condition of the vehicle and/or information about a road on which the vehicle is travelling, and controls the turning mechanism to adjust the turning angle of the turning mechanism to the target value. A transfer ratio adjuster adjusts the transfer ratio in accordance with the body posture parameter during execution of the automatic steering mode. |
US10843718B1 |
Construction safety railing assemblies, components, and methods for storage, transport, and installation
The construction industry ranks among the largest and most dangerous industries in the world. To promote worker safety, government regulations require use of fall protection equipment, such as railings, many of which are expensive, wasteful, and/or time consuming to use. Accordingly, the present inventor devised some alternatives. One exemplary system incorporates a dual post base plate configured for attachment to a concrete floor via a single concrete anchor bolt, instead of the multiple bolts used conventionally, thereby reducing assembly time and cost. Another embodiment includes a rolling cart assembly which stores the rails in a side-by-side vertical arrangement and the base plates in an interleaved sequence, promoting easy access during installation and inventory control during disassembly and storage. Additionally, some embodiments include four stacking posts that extend upward from the cart, enabling multiple carts to be stacked vertical on atop the other to save space on construction sites. |
US10843717B2 |
Trailer dolly
Herein is disclosed a dolly for carrying a heavy object by means of a car with a trailer hitch. The dolly includes a rigid frame adapted to securely hold an object on a front face of the rigid frame. Left and right parallel pneumatic wheels are positioned on a left and right sides the rigid frame, respectively and extending perpendicularly away from the rigid frame opposite a platform. Each of the pneumatic wheels is highway rated. Each of the pneumatic wheels has a hub rotatably mounted to the rigid frame by a flange member projecting perpendicularly from the rigid frame, the flange members positioning the hubs away from the rigid frame such that the hubs are at least several inches from a back face of the rigid frame. The dolly also includes a retractable boom having a trailer hitch coupling on a distal end. The retractable boom is selectively movable between a retracted and extended position. Finally, the dolly includes a lock for releasably locking the retractable boom in its extended position. |
US10843716B2 |
Method and apparatus for an interlocking control device
A distributed interlocking device, architecture and process are disclosed, and are based on segregating vital logic for a signal installation by type of signal equipment. A plurality of intelligent signal devices is disclosed, wherein each intelligent signal device is used to control a basic signal unit. A signal unit includes a set of signal apparatuses that are geographically and logically interrelated. An intelligent signal device receives data related to the states of other signal devices, determines and controls its own operational states, and communicates its own operational states to other devices. A generic intelligent signal device is also disclosed. Further, a plurality of new concepts, and signal control functions are provided, and include a vital change management process, and a failure recovery scheme based on dynamic reconfiguration of home and distant control functions. |
US10843715B2 |
Regenerative railway braking system
This invention concerns a regenerative braking system for installation on a bogie of a railway vehicle. The regenerative system includes an energy storage system for storing energy in mechanical or kinetic form, a transmission system and a control unit. The transmission system is selectively operable between different modes including a braking mode in which it transmits mechanical or kinetic energy from an axle of the bogie to the energy storage system and a drive mode in which it transmits mechanical or kinetic energy from the energy storage system to the axle of the bogie. The control unit is, in use, in communication with a prime mover of the train and the transmission system so as to receive control signals from the prime mover and automatically operate the mode of the transmission system in response to the control signals. The invention also concerns a railway bogie including a regenerative braking system, a regenerative energy management system and a method of operating the regenerative braking system. |
US10843708B1 |
User interface for displaying internal state of autonomous driving system
Autonomous vehicles use various computing systems to transport passengers from one location to another. A control computer sends messages to the various systems of the vehicle in order to maneuver the vehicle safely to the destination. The control computer may display information on an electronic display in order to allow the passenger to understand what actions the vehicle may be taking in the immediate future. Various icons and images may be used to provide this information to the passenger. |
US10843706B2 |
Vehicle control apparatus
The present disclosure relates to a vehicle control apparatus capable of making a vehicle run by automated driving. The vehicle control apparatus can include a notification unit configured to notify a course change inside and/or outside the vehicle, and a control unit. The control unit can switch the control of the notification unit stepwise in a case in which the course change is necessary before a predetermined point during the automated driving. At a first stage, the notification unit can notify the course change on condition that the state in which the course change is enabled is set. At a second stage at which the vehicle is closer to the predetermined point than at the first stage, the notification unit can notify the course change without condition that the state in which the course change is enabled is set. |
US10843702B2 |
Methods and systems for oil leak determination
Methods and systems are provided for an oil diagnostic. In one example, a method may include intrusively increasing an oil pump displacement to determine if an internal oil leak is occurring. The method may further include adjusting a parking routine to determine if an external oil leak is determining. |
US10843700B2 |
Vehicle system and method for steep slope site avoidance
A system for operating a vehicle includes a perception sensor, vehicle controls, a controller circuit, and a leveling actuator. The perception sensor is operable to determine a slope of an area within an operable range of a vehicle. The vehicle controls are operable to control movement of the vehicle. The controller circuit is in communication with the perception sensor, the vehicle controls, and the leveling actuator. The controller circuit is configured to determine, using the perception sensor, a first slope of a first site within the area to stop the vehicle, and compare the first slope to a slope threshold. In response to a determination that the first slope is steeper than the slope threshold, the controller circuit is configured to access a digital map that indicates a plurality of slopes coinciding with a plurality of locations at least comprising a second site characterized by a second slope that is not steeper than the slope threshold. The controller circuit is also configured to operate the vehicle controls to move the vehicle to the second site, and to operate the leveling actuator to level the vehicle based on the second slope upon stopping the vehicle at the second site. |
US10843695B2 |
Apparatus and program for assisting drive of vehicle
In an apparatus, a first obtainer obtains a first travelling-condition parameter of a target vehicle. The first travelling-condition parameter shows one or more conditions under which the target vehicle is travelling on the road. A second obtainer obtains a second travelling-condition parameter of a preceding vehicle travelling on the road immediately ahead of the target vehicle. The second travelling-condition parameter shows one or more conditions under which the preceding vehicle is travelling on the road. A deviation calculator calculates a deviation between the first and second travelling-condition parameters. A behavior deter miner deter mines a recommended behavior of the target vehicle in response to the calculated deviation. A controller controls a device, which is associated with a behavior of the target vehicle, according to the recommended behavior. |
US10843691B2 |
Characterizing a vehicle collision
Described herein are examples of a system that processes information describing movement of a vehicle at a time related to a potential collision to reliably determine whether a collision occurred and/or one or more characteristics of the collision. In response to obtaining information regarding a potential collision, data describing movement of the vehicle before and/or after a time associated with the potential collision is analyzed to determine whether the collision occurred and/or to determine one or more collision characteristic(s). The analysis may be carried out at least in part using a trained classifier that classifies the vehicle movement data into one or more classes, where at least some the classes are associated with whether a collision occurred and/or one or more characteristics of a collision. If a collision is determined to be likely, one or more actions may be triggered based on the characteristic(s) of the collision. |
US10843689B2 |
Collision avoidance for a connected vehicle based on a digital behavioral twin
The disclosure includes embodiments for a digital behavioral twin for collision avoidance. In some embodiments, a method includes recording digital data describing a driving context and a driving behavior of a remote vehicle and an ego vehicle in this driving context. In some embodiments, one or more of the remote vehicle and the ego vehicle is a connected vehicle. The method includes determining a risk of a collision involving one or more of the remote vehicle and the ego vehicle based on a first digital behavioral twin of the remote vehicle, a second digital behavioral twin of the ego vehicle and the digital data. The method includes modifying an operation of the ego vehicle based on the risk. |
US10843687B2 |
Arrangement and method for mitigating a forward collision between road vehicles
Disclosed is an arrangement and a method for mitigating a forward collision between a host vehicle, having sensors for monitoring a road ahead and wheel brakes, and an oncoming vehicle. The sensors are utilized to estimate parameters of an oncoming vehicle. The estimated parameters are utilized to predict a future path of the oncoming vehicle, and host vehicle parameters are utilized to predict a future path of the host vehicle. The predicted future paths are assessed to determine if a forward collision is likely unavoidable assuming full freedom for performing avoidance maneuvers for both vehicles. The wheel brakes are controlled to reduce a relative longitudinal velocity between the vehicles at a predicted collision instant if determined that a forward collision is likely unavoidable at a determined relative longitudinal velocity above a first threshold. |
US10843685B2 |
Method and system for preventing a following vehicle from driving up on a vehicle driving directly in front and use of the system
A method and system for preventing a following vehicle from driving up on a vehicle driving directly in front. The following vehicle detects a behavior of the vehicle driving directly in front by sensor information and a behavior of at least one vehicle driving in front by vehicle-to-X information. The vehicle-to-x information requests an intervention in the steering of the following vehicle by a steering angle to be set and/or an intervention in the braking of the following vehicle by a deceleration to be set in order to prevent driving up on the vehicle, and wherein the steering angle and/or the deceleration requested by the vehicle-to-X information is greater than a steering angle and/or a requested deceleration requested by the sensor information and/or driver inputs. The intervention is only carried out if the steering angle and/or the deceleration is confirmed by sensor information and/or driver inputs. |
US10843684B2 |
Parking assist apparatus
A parking assist apparatus (13) has: a learning device (131) configured to learn a first position (WP_start) that is a position of the vehicle when a driver starts a parking operation, a second position (WP_shift) that is a position of the vehicle when the driver changes a shift range of the vehicle and a third position (WP_end) that is a position when the driver completes the parking operation during a period when the driver performs the parking operation; and a generating device (132) configured to generate, as a target route (TR_target) along which the vehicle should travel when the vehicle is automatically parked, a traveling route that reaches the third position from the first position via the second position on the basis of a learning result. |
US10843683B2 |
Vehicle control device and method
The present invention provides a vehicle control device and method capable of ensuring steering accuracy. In a vehicle provided with a left-right pair of steered wheels for which the braking/driving forces can each be controlled, and a steering force generation device that generates steering force for the steered wheels and controls the steering angle of the steered wheels, this vehicle control device and method control the steering force and the steering reaction force from the steering force generation device by controlling the braking/driving force of each of the steered wheels on the basis of the lateral force acting on the steered wheels. |
US10843682B2 |
Vehicle controller
A vehicle controller calculates a lateral slip amount indicating a degree to which a target wheel to be controlled which is a front wheel or a rear wheel of a vehicle is slipping in a rightward and leftward direction on a ground surface; performs a lateral slip suppressing control including at least one of a control for reducing an absolute value of a command value of a longitudinal force in a forward and rearward direction which is applied from the ground surface to the target wheel and a control for increasing a distributed load applied to the target wheel, in a case where it is determined that the lateral slip amount is greater than a lateral slip limit threshold; and decides the lateral slip limit threshold based on at least one of the longitudinal force and a normal force applied to the target wheel. |
US10843675B2 |
Actuator for electromechanical parking brake having housing with brush card assembly
An actuator for an electromechanical parking brake having a housing with a brush card assembly is provided, which includes: a main housing having a motor seat and a gear seat; a motor assembly disposed in the motor seat and providing torque; a gear assembly rotated by torque from the motor assembly and performing a reduction function through a plurality of gears; and an inner housing. The inner housing is combined with the main housing and fixes the gear assembly, and integrally has a ring gear operating in mesh with a planetary gear seat of the gear assembly and a brush card electrically connected to the motor assembly. A ring gear operating with the planetary gear set and a brush card electrically connected to the motor assembly are integrally formed at the inner housing. |
US10843672B2 |
Hybrid vehicle engine brake with manual override
A power split hybrid powertrain includes an electrically actuated brake that selectively engages a ring gear attached to a flywheel. The ring gear may be, for example, a starter ring gear. Engagement of the brake while the engine is stopped permits use of both electric machines to provide torque to vehicle wheels, thereby increasing the electric torque capacity of the powertrain. The brake is mounted for movement relative to the ring gear, and a mechanical linkage is attached to the brake. In the event of a malfunction of the brake that prevents normal operation of the powertrain, the linkage is manually actuatable by a vehicle operator to move the brake to an override position wherein it cannot engage the ring gear. |
US10843671B2 |
Housing block, in particular for a hydraulic unit of an electronically slip-controllable vehicle brake system
A drilling tool, in particular a rock drilling tool, for a portable machine tool, includes a drill head, in particular a hard metal drill head. The drill head includes a drill shaft connected, in particular integrally with the drill head, and a rotational axis. The drill shaft is configured as one piece, has a guide section with guide groove winding in a spiral-shaped about the drill shaft for transporting away drilling dust, and has a securing section provided for detachably securing the drilling tool to a machine tool. The guide section has a diameter reinforcement at a drill head support region of the guide section neighboring, in particular adjacent to, the drill head. |
US10843663B2 |
Windshield wiper system with actively movable platform
This disclosure relates to techniques for implementing a windshield wiper system with an actively movable platform. The windshield wiper system can include a windshield wiper arm mechanically coupled to a platform and an actuator mechanically coupled to the platform. The windshield wiper arm can be configured to move through a planar range of motion that is substantially parallel to a surface of a vehicle when the platform is positioned at a first spatial location and the movable windshield wiper arm can be configured constrained from moving through the planar range when the platform is positioned at a second spatial location. |
US10843657B2 |
Seat belt buckle tongue with a deflecting element
A seat belt buckle tongue (1) with a tongue body (3) extending in the direction of plug-in (2), in which a strap slot (4) is formed for the passage of a strap (5), and a deflection element (6) movably the tongue body (3), The strap (5), in an unloaded passage position of the deflection element (6), is movable through the strap slot (4), and is at least prevented from moving by the deflection element (6) in the loading position of the deflection element (6) induced by a tensile force to the strap (5). The deflection element (6) is movable from the passage position into the loading position with a constriction portion (18) along the contact surface (19) of the tongue body (3), so that the strap (5) in the loading position with a strap portion is flat in contact with both the contact surface (19) of the tongue body (3) and with the constriction portion (18) of the deflection element (6). In the loading position, the tongue body (3) engages with a region having the contact surface (19), through at least the portion of the deflection element (6). |
US10843653B2 |
Vehicle seat and vehicle
A vehicle seat, which is provided in a vehicle equipped with a head portion protecting airbag that protects a head portion of a vehicle occupant at a time of a side collision, includes: a head portion restraining portion that is provided at an upper portion side of a seatback so as to be able to tilt rearward from an upright state, and that restrains a head portion of a vehicle occupant, wherein, when the seatback is tilted rearward beyond a predetermined angle with respect to a vertical direction, the head portion of the vehicle occupant can be protected due to at least a side portion that is at a vehicle transverse direction outer side of the head portion restraining portion covering a side of the head portion of the vehicle occupant. |
US10843651B2 |
Monument mounted airbag
A monument mounted airbag system for arresting passenger movement during a sudden acceleration/deceleration event of a moving vehicle includes an airbag assembly including at least one airbag on a first portion of a monument structure, the airbag assembly having a housing at least partially defined by a space between an external member and the monument structure. |
US10843649B2 |
System for providing protection to a track type tractor
A system for providing protection to a track type tractor includes a sweep arrangement having a pair of arms that are supported on a cab of the track type tractor. The pair of arms have first ends that are disposed rearwardly of the cab. The pair of arms also extend forward of an engine compartment of the track type tractor and have second ends that are coupled with a housing of the engine compartment. The system also includes a cross-brace having a pair of clamps and a bar. The clamps are releasably fastened onto the pair of arms of the sweep arrangement and located at an anterior region of the track type tractor. The bar has a pair of ends that are releasably fastened to proximal ends of the pair of clamps. |
US10843648B2 |
Crash structure for a vehicle
A crash structure for a vehicle, including a bumper crossmember of which the end portions are each connected to a corresponding longitudinal member via a crash box. End regions of the end portions each project in the vehicle transverse direction beyond the corresponding longitudinal member. In each case a first supporting element which protrudes in the direction of a corresponding wheelhouse is arranged at the end regions and, in an accident situation with slight overlapping of the other party in the accident, impinges on the corresponding longitudinal member. In each case a second supporting element is arranged at the end regions of the end portions and, in the accident situation with slight overlapping of the other party in the accident, impinges on a corresponding connecting region between the crash box and the longitudinal member. |
US10843644B2 |
Vehicle liftgate window assembly with heater grid
A rear liftgate window assembly for a vehicle includes a glass window panel configured to be pivotally mounted at a rear portion of a vehicle so as to be pivotable between a closed position and an opened position. A heater grid includes a plurality of electrically conductive traces established at the inner surface of the glass window panel. A pair of busbars are established at the inner surface of the glass window panel and extend outboard of at least one side region of the inner surface of the window panel that contacts a seal at the vehicle when the glass window panel is in the closed position. Electrical connectors are electrically connected to the busbars outboard of the side region. The electrical connectors are configured to electrically connect to a power source of the vehicle when the rear liftgate window assembly is mounted at the vehicle. |
US10843642B2 |
License plate fastener head cap assembly
A hardware hider cap assembly is provided for covering a fastener, and more specifically, covering a fastener head. The hider cap assembly can include a base member with an opening for receiving the fastener and a cap member releasably coupled to the base member via a threaded engagement. The cap member can include a tab or protrusion configured to engage with a notch in the base member, thereby preventing overtightening of the cap member onto the base member. |
US10843640B2 |
Vehicle with locator device configured to maintain outer body panel alignment, and corresponding method
This disclosure relates to a motor vehicle with a locator device configured to maintain outer body panel alignment, and a corresponding method. In particular, an example method includes temporarily attaching a locator device to one of a body of a motor vehicle and an outer body panel connectable to the body. The method further includes connecting the outer body panel to the body, and rigidly connecting the locator device to the other of the body and the outer body panel. |
US10843639B2 |
Pillar garnish
An elongated pillar garnish configured to be attached to a gap between a peripheral edge portion of a window pane of a vehicle and a pillar of the vehicle, the pillar garnish including: an elongated attachment member for attaching the pillar garnish to the gap; and an elongated decorative member assembled to a front surface side of the attachment member, in which the attachment member includes an elongated main body part, and a cover part provided to at least one end of the main body part in a longitudinal direction, in which the cover part has a covering portion covering at least a part of a front surface of the decorative member, and a supporting wall portion erected from the main body part toward the outer side and supporting the covering portion, and in which the supporting wall portion is provided along a direction intersecting with the longitudinal direction. |
US10843634B2 |
Operator console
A cover for an operator console of a machine includes a first section rotatably coupled to the operator console. The first section selectively rotates between a first position and a second position about a rotational axis. The cover also includes a second section rotatably coupled to the operator console and the first section. The second section selectively rotates between a third position and a fourth position about the rotational axis. The second section is also adapted to engage with the first section during rotation of the second section from the third position to the fourth position to rotate the first section from the first position to the second position. The second section is further adapted to engage with the first section during rotation of the second section from the fourth position to the third position to rotate the first section from the second position to the first position. |
US10843631B1 |
Pickup truck bed access ladder
An access ladder for access to a pickup truck bed. The access ladder includes a base having a pair of spaced apart “J” shaped brackets, with the proximal end having an open jaw sized and shaped so that it can be releasably secured to the pickup truck bed. The “J” shaped brackets are spaced apart by spacers, and optionally, a step plate. A protective mat may be provided to protect the surface of the pickup truck bed against scratching or abrasion. A handle may be provided for assisting users with balance as they ingress or egress from a pickup truck bed. A plurality of steps are affixed to the “J” shaped brackets. The steps are provided at fixed intervals along a pair of flexible support members, which in an embodiment, may be ropes. Support stops are used to set spacing of steps along the flexible support members. Bumpers may be provided at each step to further protect the outer surface of the pickup truck. |
US10843630B2 |
Backing plate unit, method for producing such a backing plate unit and rear view device for a motor vehicle with such a backing plate unit
A backing plate unit for a rear view device for a motor vehicle includes at least one opening passing from a rear side of a backing plate to a front side thereof to form a logo pattern by itself, first attachment means on the rear side of the backing plate for a light source, and light filter means and/or at least one extension which is extending from the front side of the backing plate in the region of the logo pattern. A method for producing such a backing plate unit and a rear view device with such a backing plate unit are also described. |
US10843624B1 |
System and method for providing haptic counteractions and alerts within a seat of a vehicle
A system and method for providing haptic counteractions and alerts within a seat of a vehicle that include determining that at least one front seat passenger is occupying at least one front passenger seat and at least one rear seat passenger is occupying at least one rear passenger seat. The system and method also include determining a location of the at least one rear seat passenger with respect to a location of the at least one front seat passenger within the vehicle and determining if at least one disturbance is affecting the at least one front passenger seat. The system and method further include actuating at least one vibrational element to counteract the at least one disturbance affecting the at least one front passenger seat and to provide a reminder alert pertaining to the at least one rear seat passenger to the at least one front seat passenger. |
US10843621B2 |
Lever switch and automatic light control device
A lever switch includes a lever main body and a rotary operation element rotatably provided at a tip end portion of the lever main body. The rotary operation element is provided with a light ON switch position at which an instruction to cause head lights and small lights to be on at all times is issued, an automatic light switch position at which an instruction to set an automatic light mode, in which a turned-on state of the head lights and the small lights is controlled based on the intensity of illumination in the vicinity of the vehicle, is issued, and a light OFF switch position at which an instruction to turn the head lights off is issued, the light ON switch position, the automatic light switch position, and the light OFF switch position being arranged in an order along a rotation direction. |
US10843616B2 |
Electric transportation cart with adjustable deck
An electric transportation cart includes a deck having two first rails located on two sides thereof a base having multiple casters connected to the underside thereof and including two second rails on two sides thereof, a first link assembly and a second link assembly pivotably connected between the deck and the base, and a handle connected to one end of the base. A first bar is slidably connected between the two first rails, and a second bar is connected between the first link assembly and the second link assembly. A hydraulic cylinder is connected between the first bar and the second bar. The travel distance of the hydraulic cylinder is longer than that of the conventional transportation carts. Users operate the control unit to activate the hydraulic cylinder to drive the first and second link assemblies to control the deck to move up and down. |
US10843612B1 |
Leg support system for seating assembly
A vehicle seating assembly includes a seat and a base member with a support member pivotably coupled to the seat and rotationally movable between first and second positions. A bracket assembly is disposed between the support member and the base member and is coupled to an actuator. A supplemental support member is coupled to the bracket assembly and the support member. The supplemental support member is translationally movable relative to the support member between a retracted position and a fully extended position. |
US10843600B2 |
Vehicle seat trim covers including integrally-knit backing materials and methods of manufacturing vehicle seat trim covers
A trim component for attachment to a vehicle seat includes a first portion and a second portion. The first portion is disposed on a first side of the trim component and defines a first knit. The second portion is disposed on a second side of the trim component and defines a second knit distinct from the first knit. The first and second portions are integrally knitted. The trim component is configured to be installed on or more support members of the seat. The first side is configured to face the support member. The second portion is configured communicate with an occupant of the seat. In various aspects, the first portion includes a first yarn and the second portion includes a second yarn that is distinct from the first yarn with respect to one or more of density, thickness, and material. In various aspects, the first yarn is a heat-activated yarn. |
US10843598B2 |
Child safety seat
A child safety seat (1) including a seat base (12) having an upper surface (13) and a lower surface (14) and comprising at least one elongate slot (15) extending through the seat base (12) between the upper surface and the lower surface (13, 14), a crotch strap (20) extending downwardly from a buckle (21) which is above the upper surface (13) of the seat base (12), wherein the crotch strap (20) extends through the at least one elongate slot (15) and has at least one end (22) slidably retained in relation to the seat base (12), and a crotch strap adjustment mechanism (30) configured to act on an intermediate portion of the crotch strap (20), the adjustment mechanism (30) being slidable with respect to the seat base (12) in an oblique direction relative to the direction of elongation of the at least one elongate slot (15) to adjust both the position of the crotch strap (20) exiting the at least one elongate slot (15) and the length of the crotch strap (20) extending above the upper surface (13) of the seat base (12). |
US10843595B2 |
Vehicle seat
A vehicle seat including, a seat cushion including: a pair of left and right base members; a seat cushion movable portion attached in a manner that enables tip-up around a rotation shaft disposed between the base members; and a seat cushion fixed portion fixed in a manner that an upper surface portion of at least one of the base members is partially overlapped with the seat cushion fixed portion, and a distance between the base members is smaller than a sum of widths of a rear end portion of the seat cushion movable portion and a rear end portion of the seat cushion fixed portion, and the seat cushion movable portion selectively adopts a normal state where the seat cushion movable portion forms a seating surface together with the seat cushion fixed portion, and a tip-up state without interfering with the seat cushion fixed portion. |
US10843594B2 |
Adjustable seat with entry tip slide plus pitch slide
A seat mounted on a slide slidable on a track. The track has comfort and entry zones. Pitch linkage mounts on the slide and supports a seat back. The linkage pivotally connects a seat back to the slide between recline and forward positions. A track latch fixes the slide to the track in a plurality of positions in the comfort zone. The entry zone is used to enter the vehicle. A forward stop blocks the slide from moving from the comfort to the entry zone. The forward stop moves between stop and release positions. The stop position blocks the slide from moving from the comfort to the entry zone. The release position does not block the slide from moving. A forward stop mechanism moves the forward stop into the stop position when the pitch linkage is in the recline position and the slide is in said comfort zone. |
US10843593B2 |
Adjusting device for longitudinal adjustment of a vehicle seat
A rail assembly for longitudinal adjustment of a vehicle seat comprises a lower rail (2) and an upper rail (1) movable relative to the lower rail, and a movable support member (400) disposed between the lower rail (2) and the upper rail (1), wherein the lower rail (2) comprises a stopper (210) disposed at a predetermined position of the lower rail (2), and the movable support member (400) comprises a base (40) for supporting the upper rail (1) on the lower rail (2) and a coupling member (47) for releasably coupling the movable support member (400) with the upper rail (1).The coupling member (47) can be displaced relative to the base. Movement of the movable support member (400) relative to the lower rail (2) in the longitudinal direction is stopped by the stopper (210) at the predetermined position, and displacement of the coupling member (47) relative to the base (40) is controlled by the position of the upper rail (1), for controlling a coupling and decoupling of the movable support member (400) to the upper rail (1). |
US10843576B2 |
Electric vehicle
An electric vehicle includes front-wheel electric motor and rear-wheel electric motor driving front and rear wheels, respectively; a control unit controlling driving of those electric motors. Further, one of the electric motors is a permanent-magnet motor and the other is a magnetless motor, a maximum output of the permanent-magnet motor is smaller than a maximum output of the magnetless motor, and the control unit includes: a first drive control unit configured to drive the permanent-magnet motor when vehicle speed is in a first vehicle-speed range; and a second drive control unit configured to drive only the magnetless motor when the vehicle speed is in a second vehicle speed range, vehicle speeds in the second vehicle speed range are greater than vehicle speeds in the first vehicle-speed range. |
US10843575B2 |
Control system for controlling operation of a drive motor
A control system for controlling operation of a drive motor includes an input device for providing a command signal that is indicative of a desired speed and direction of rotation of the drive motor. A sensor is associated with the drive motor and adapted to provide a sensor signal indicative of current rotational speed of the drive motor. A controller receives the command signal, and determine whether the command signal is indicative of a desired zero speed to be associated with the drive motor. The controller also receives the sensor signal, and determine whether the current rotational speed of the drive motor is within a pre-defined range of difference from the desired zero speed. The controller then generates a de-rated torque command signal having a reduced gain factor, and reduce the current rotational speed of the drive motor based on the de-rated torque command signal. |
US10843574B2 |
Calibration and programming of in-vehicle battery sensors
An in-vehicle battery sensor includes a sensor configured to couple to a storage battery. A memory is configured to store calibration information. An input receives calibration information which is saved in the memory. A controller performs a battery test on the storage battery using the sensor output and the stored calibration information. |
US10843573B2 |
Charging station and charging station module
A charging station is provided herein for being adapted to bear an unmanned vehicle. The charging station includes a platform and a charging mechanism. The charging mechanism is disposed on the platform, and the charging mechanism may be electrically connected to the unmanned vehicle for charging by a movement over the platform. In addition, a charging station module including a plurality of the aforesaid charging stations is also provided. |
US10843567B2 |
Monitoring system
A monitoring system includes: a first monitor that receives, from a first output terminal, a voltage detected by a voltage detector and information on a circuit failure; a second monitor that receives, from a second output terminal, an abnormal voltage signal detected by the voltage detector; and a vehicle controller that electrically disconnects a driving motor from an electricity storing unit. When a circuit failure occurs in one circuit of a circuit on a side of the first output terminal and a circuit on a side of the second output terminal and a circuit failure does not occur in the other circuit, and the electricity storing unit is normal, the vehicle controller connects the driving motor with the electricity storing unit. |
US10843564B2 |
Control system for all-wheel drive vehicle
A vehicle includes a first axle temporary driven by a motor, a second axle permanently connected to the motor via a propeller shaft, and a sub-shaft that connects the propeller shaft and the first axle. A control system for a connection between the motor and the first axle includes a first clutch between the propeller shaft and the sub-shaft, a second clutch between the sub-shaft and the first axle. The first clutch is controlled to continue applying a synchronous torque until the second clutch is determined to be connected. The second clutch is controlled to be connected in response to a determination that the second clutch is connectable. |
US10843559B2 |
Power transmission device for four wheel drive vehicle
In a power transmission device of a four-wheel drive electrically driven vehicle, the power source includes a transverse engine supported on one side surface of a gear case, and a motor supported on the other side surface. A transfer case is supported on the same side surface of the gear case as the motor. The transfer case has a transfer input shaft arranged in the vehicle width direction, a transfer output shaft arranged in the longitudinal direction of the vehicle, a bevel gear pair and a transfer gear pair. The bevel gear pair and the transfer gear pair transmit power by changing a rotational axis direction to an essentially orthogonal direction between the transfer input shaft and the transfer output shaft. An output shaft gear provided on the transfer output shaft of the transfer case is disposed in a position overlapping the gear case in a vehicle width direction. |
US10843555B2 |
Opening/closing device of fuel tank
In a housing surrounding a nozzle insertion passage, a first opening open to the atmosphere is provided, and in a cover main body in which the housing is incorporated, a nozzle insertion port and a second opening which is opposite the first opening and open to the atmosphere is provided. Moreover, in the recess wall of a drainage port formation member fitted to the first opening, a recess which is recessed on the side of the first opening is formed so as to be continuous with the second opening, and a drainage port is provided. A drainage valve is held in the recess with respect to the recess wall so as to open and close the drainage port by turning of the valve main body about the turning shaft serving as a base point. |
US10843552B2 |
Motorcycle intake air guide for a motorcycle engine
A motorcycle intake air guide for guiding an intake air volumetric flow from a front region of a motorcycle to a motorcycle internal combustion engine includes a front air guiding duct, a rear air guiding duct arranged downstream of the front air guiding duct, and a steering head bypass region arranged between and connecting the front and the rear air guiding ducts to one another. The front and the rear air guiding ducts have a closed profile. The steering head bypass region preferably has, in a steering head cross-sectional plane which is arranged orthogonally with respect to a main flow direction of the intake air volumetric flow in the steering head bypass region, a non-closed profile for guiding the intake air volumetric flow around a steering head recess through which a steering head of the motorcycle extends. The steering head may close the non-closed profile at the steering head recess. |
US10843542B2 |
Retractable trailer enclosure system
A retractable trailer enclosure system includes a flexible cover, rotatable winding spindle moveable by way of a spindle guide assembly. The spindle guide assembly includes a drive assembly actuable to rotate the spindle, a shuttle assembly mounting a spindle end and a guide track assembly which guides the shuttle assembly in reciprocal movement along both a vertical cover deployment/retraction path, and laterally along a spindle storage path. |
US10843539B2 |
Tensioner apparatus for use with vehicle sunroofs
Tensioner apparatus for use with vehicle sunroofs are disclosed. A disclosed assembly for a vehicle sunroof includes a sunshade tensioner defining a body that is configured to engage a sunshade of the vehicle sunroof to prevent the sunshade from wrinkling. The assembly also includes a first tab supported by a first component of the vehicle sunroof. The first tab is configured to extend through a first aperture positioned on the body to removably couple a first end of the body to the first support component. |
US10843537B2 |
Door beam
A door beam includes an aluminum alloy extrusion body extended in a longitudinal direction and having a pair of webs and a pair of flanges to be positioned on an inner side and an outer side in a width direction of a vehicle body. The pair of webs connect the pair of flanges at joint portions of each of the pair of webs such that the pair of webs and the pair of flanges form a closed cross section in a direction perpendicular to the longitudinal direction, and the pair of webs do not have a welded portion. |
US10843536B2 |
Sectorized adaptive screen and driver assistance system comprising such an adaptive screen
An adaptive screen including at least one liquid crystal shutter. At least one of the shutters includes at least two active zones which are addressed by a control signal which permits the switchover of the at least one corresponding shutter between a passing configuration, in which a transmittance is equal to a maximum value, and a blocking configuration, in which the transmittance is equal to a minimum value. A “principal” active zone covers a surface area of the adaptive screen which is equal to or lower than 60% of the surface area of the adaptive screen, in order to reduce the response time of the principal active zone. |
US10843534B2 |
Remotely operated sun visor
A remotely operated sun visor includes a first rotational mechanism, a second rotational mechanism, a sun visor body, a controller unit, and a power switch. The first rotational mechanism and the second rotational mechanism are perpendicularly positioned of each other in such a way that the first rotational mechanism is internally positioned along the sun visor body and the second rotational mechanism is internally positioned across the sun visor body. The sun visor body being torsionally connected to the first rotational mechanism so that the sun visor body can be rotated up and down, about an automobile windshield. The sun visor is torsionally connected to the second rotational mechanism so that the sun visor body can be rotated from the windshield to the side windows, about an automobile A-pillar. The first rotational mechanism and the second rotational mechanism are electrically connected to the power switch through the controller unit. |
US10843531B2 |
Cold formed laminates
The principles and embodiments of the present disclosure relate generally to complexly curved laminates made from a complexly curved substrate and a flat substrate, such as automotive window glazings, and methods of cold forming complexly-curved glass products from a curved substrate and a flat substrate. In one or more embodiments, the laminate includes first complexly-curved glass substrate with a first surface and a second surface opposite the first surface, a second complexly-curved glass substrate with a third surface and a fourth surface opposite the third surface with a thickness therebetween; and a polymer interlayer affixed to the second convex surface and third surface, wherein the third surface and fourth surface have compressive stress values respectively that differ such that the fourth surface has as compressive stress value that is greater than the compressive stress value of the third surface. |
US10843530B2 |
Vehicle air conditioning device
A vehicle air conditioning device includes a compressor and a controller. The controller is configured to set an upper limit value of the rotation speed of the compressor based on a combination of whether the speed of the vehicle is lower than a predetermined speed and whether a rotation speed of a fan device for a condenser is lower than a predetermined rotation speed. |
US10843528B2 |
Heat pump air-conditioning system and electric vehicle
A heat pump air-conditioning system includes a HVAC assembly, a compressor, an outdoor heat exchanger, and a first plate heat exchanger. The HVAC assembly includes an indoor condenser, an indoor evaporator, and an damper mechanism. The compressor communicates to the indoor condenser. The indoor condenser communicates to the outdoor heat exchanger and further to the outdoor heat exchanger through a first enthalpy-increased branch. The outdoor heat exchanger communicates to the indoor evaporator and further to a moderate-pressure air inlet of the compressor through a second enthalpy-increased branch. The indoor evaporator communicates to a low-pressure air inlet of the compressor. The first enthalpy-increased branch and the second enthalpy-increased branch exchange heat by using the first plate heat exchanger. The second enthalpy-increased branch is provided with a first expansion valve. The outdoor heat exchanger is in communication with the first plate heat exchanger through the first expansion valve. |
US10843521B2 |
Method and apparatus for mitigating static loads in components connecting multiple structures
An apparatus and method are described where one or more pre-stressed spring elements are disposed between two structures to mitigate or cancel the effect of static loads applied to a component connecting the structures. The apparatus and methods may be used, for example, to reduce the adverse impact of static loads on the performance of top-mounts in a suspension system of a vehicle. |
US10843517B2 |
Isolated lift assembly for vehicle auxiliary suspension arrangement
A vehicle suspension assembly includes a mounting bracket adapted to couple to a vehicle frame assembly, a trailing arm having a first end pivotably coupled to the first mounting bracket, and a second end, an axle member coupled to the second end of the trailing arm, the axle member configured to support a tire, an actuator operably coupled to the trailing arm and operable between a first state configured to lift the tire away from a ground surface and a second state configured for the tire to contact the ground surface, and an actuator arrangement configured to move from a first position where the actuator arrangement couples the actuator to the trailing arm when the actuator is in the first state, and a second position where the actuator arrangement uncouples the actuator from the trailing arm when the actuator is in the second state. |
US10843515B2 |
Trailer control device for mounting on a trailer
A trailer control device for mounting on a trailer, wherein the trailer control device includes a receiver unit configured to receive a signal from an external transmitter unit, a comparator connected to the receiver unit and configured to compare the received signal with a pre-defined signal stored in the comparator, and a transmitter unit connected to the comparator and configured to send a response signal to an external receiver unit for locating and/or identifying the trailer control device if the received signal matches the pre-defined signal. |
US10843514B2 |
Hitch plate assembly
A hitch plate assembly for a truck. The hitch plate includes a lower frame spanning beneath a pair of frame rails of the truck. The lower frame is fabricated from a front plate and end plates at oppositely disposed ends of the front plate. The end plates extend upwardly for attachment directly to the frame rails. An upper frame is mounted over the lower frame and between the frame rails. The upper frame is comprised of a front plate, two side plates, an upper plate and two pairs of spaced apart pivot plates with through holes therein secured to the upper plate, wherein a dump body hinge is received into the space between each pair of pivot plates and each hinge is secured in position by a pin, the dump body being rotatable about each pin. |
US10843513B2 |
Safety chain tie down apparatus
A tie down apparatus for securing an item is shown and described herein. The tie down apparatus may include first and second body members, where the first body member is configured to be located and rotated about a first axis within a first receiving member and the second body member is configured to be located and rotated about a second axis within a second receiving member. The tie down apparatus may also include first and second locking members each extending through the first and second body members, respectively, where rotating the first and second body members about the respective first and second axes engages the first and second locking members and generally prevents removal of the first and second body members from the first and second receiving member, and a safety chain holding member selectively engaged with either of the first and second body members. |
US10843512B2 |
Brake pad wear sensor with wireless data transmission
A vehicle wheel monitoring device includes a tire pressure monitoring unit, a tire pressure sensor unit disposed at a wheel of the vehicle and a brake pad wear sensor unit disposed at a wheel of the vehicle. The brake pad wear sensor unit includes a brake pad wear sensor and a wireless transmitter configured to receive the signal emitted from the brake pad wear sensor and wirelessly transmit it to the tire pressure monitoring unit. An energy harvesting device is configured to convert energy derived from an external source into electrical power, and to provide the electrical power to the brake pad wear sensor unit and the transmitter. The brake pad wear sensor unit and the tire pressure sensor unit are monitored by the tire pressure monitoring unit. |
US10843506B2 |
Omni-directional rotational drive mechanism and moving body
An omni-directional rotational drive mechanism and a moving body in which production and maintenance can be facilitated, while the size can be reduced, by making the number of components smaller. A rotating body provided for a wheel member rotatable about a ring-shaped shaft having a rotating shaft of the wheel member as its center. The rotating body is configured to rotate integrally with the wheel member about the rotating shaft. A pair of worms rotatable about the same shaft as the rotating shaft of the wheel member. A pair of worm wheels are provided for the wheel member so as to be rotatable by meshing with different worms, and capable of transmitting each of rotations to the rotating body. The rotating body is configured so as to rotate or stop with respect to the wheel member in accordance with the rotational direction and the rotational speed of the respective worms. |
US10843500B2 |
Watermark sheet, apparatus, and document, and methods for providing the same
A watermark sheet made up of a substrate layer with opposing water and fiber surfaces, a pattern of at least two watermark indicia, and a set of apertures extending from the water surface toward the fiber surface of the substrate layer, is provided. The pattern of at least two watermark indicia is distributed over a continuous area of the fiber surface. The inventive watermark sheet provides watermarks of improved quality. Also provided is a watermark sleeve made up of a cylinder mold and the inventive watermark sheet wrapped around and affixed to an outer diametric surface of the cylinder mold. In addition, methods of manufacturing the watermark sheet, the watermark sleeve, a watermarked paper and a high security document are provided, as well as products resulting from these methods of manufacture. |
US10843498B2 |
Automated process for the manufacture of at least one printed work from at least one sheet
The invention concerns a process and a system for the digital printing of printed publications, for the flexible production, on demand, of a single publication or small series of publications. The process of the invention is an automated process for the manufacture of at least one publication printed from at least one sheet, comprising the steps wherein: a plurality of pages (1, 4, 5, 8) of the publication is printed (A) on the sheet (10) that is moved through a series of stations wherein, subsequently, the sheet (10) is folded (C) in half perpendicular to the direction of travel; the folded sheet (10) is pivoted (D) by 90° with respect to the direction of travel, and the edges (18, 19) of the folded sheet are trimmed to obtain separate, superposed leaves (16, 17). |
US10843495B2 |
Power supply device, conveyance apparatus, and image forming apparatus
A power supply device includes a power supply line, control circuitry, and a first switch. The power supply line supplies voltage from a first power supply unit to a load. The control circuitry controls voltage supply from the first power supply unit. The first switch is connected between a second power supply unit and the control circuitry. The control circuitry causes the first power supply unit to start the voltage supply on condition that the first switch is in a closed state and a voltage of the power supply line is not greater than a first threshold voltage, and causes the first power supply unit to start the voltage supply on condition that the voltage of the power supply line is not greater than a second threshold voltage higher than the first threshold voltage when the first switch changes from an open state to the closed state. |
US10843494B2 |
Stay rod and inkjet recording apparatus
A stay rod includes a guide to slidably hold a functional part, the guide to be fixed to an apparatus body, a plurality of first parts each including a guide surface to form the guide, and a plurality of second parts each including a mounting surface to be mounted to the apparatus body. The plurality of first parts and the plurality of second parts are combined to have an elongated box-shaped cross section in which the guide surface of the plurality of first parts faces the mounting surface of the plurality of second parts, the plurality of first parts is arranged side by side in a longitudinal direction of the stay rod and is joined to the plurality of second pars at each joint formed at each end of the plurality of first parts. |
US10843492B2 |
Magnetic-ink reading device and printer
A magnetic-ink reading device includes a housing and a conveyor in the housing. A medium inlet and outlet port for inserting and pulling out a medium printed using magnetic ink are in the housing. The conveyor conveys the medium along a conveying path. The magnetic-ink reading device includes a magnetizing mechanism configured to magnetize the magnetic ink of the medium on the conveying path and a magnetism detection head disposed near the magnetizing mechanism and configured to read magnetism of the magnetized magnetic ink. The magnetic-ink reading device includes a reversing mechanism provided on the medium inlet and outlet port side of the conveying path and configured to reverse front and rear surfaces of the medium on a reversing path on an inside. The reversing mechanism includes a retraction path for temporarily retracting the medium when the magnetism of the medium is read by the magnetism detection head. |
US10843487B2 |
Ink drying apparatus for drying ink by heat after printing
A compact ink drying apparatus is capable of drying ink ejected to a resin substrate. The ink drying apparatus has a hot air dryer, a hot air supplying part, and an exhausting part. The hot air dryer has a drying furnace, a substrate conveying path formed as a spirally shaped path in the drying furnace, and substrate drying ducts blowing hot air to a surface of a resin substrate on which ink is ejected conveyed along the substrate conveying path to heat ink and exhausting water vapor generated by heating of ink. The hot air supplying part is outside the drying furnace and supplies hot air into the substrate drying ducts, and the exhausting part is outside the drying furnace and exhausts air in the drying furnace through the substrate drying ducts. |
US10843485B2 |
Printing device
An image is formed on a can body by use of plural image formation units. A printing device (500) is provided with a moving unit (550) that moves while supporting can bodies (10). Additionally, the printing device (500) is provided with a printing unit (520) that includes plural inkjet heads (11W), (11C), (11M), (11Y), (11K) and that performs printing on the can bodies (10) supported by the moving unit (550). Further, the printing device (500) is provided with a moving mechanism (560) that causes the moving unit (550) to move by using a linear mechanism. |
US10843481B2 |
Liquid ejection apparatus
A liquid ejection apparatus capable of detecting ink leakage early is provided. For this purpose, an ink leakage detection pin and a wall capable of storing leaked ink are provided at a joint part which is the part connecting the print head and the ink supply unit. |
US10843480B2 |
Inkjet printing apparatus and control method of inkjet printing apparatus
An inkjet printing apparatus includes: a print head provided with an ejection opening surface; a tank; a supply flow path; a collection flow path; an intra-tank vacuum pump to reduce pressure inside the tank; and a control unit. The control unit performs a first operation and a second operation, the first operation causing the intra-tank vacuum pump to operate while a collection drive valve is closed, so as to pull out ink in a flow path which extends from the ejection opening to the supply flow path into the tank, the second operation causing the intra-tank vacuum pump to operate while a supply drive valve is closed, so as to pull out ink in a flow path which extends from the ejection opening to the collection flow path into the tank. |
US10843479B2 |
Liquid supply apparatus, liquid discharge apparatus, and liquid supply method
A liquid supply apparatus comprises: a liquid supply unit to perform an operation to supply liquid from a main tank to a sub tank; a liquid surface detection unit configured to detect a liquid surface of the liquid stored in the sub tank; and a control unit configured to control the liquid supply unit to execute first liquid supply operation to control the liquid supply unit to supply liquid to the sub tank until the liquid surface is detected by the liquid surface detection unit and a second liquid supply operation to supply liquid to the sub tank after the liquid surface is detected by the liquid surface detection unit. The control unit controls, based on at least one of a liquid supply amount and a liquid supply time in the first liquid supply operation, the time during which the second liquid supply operation is executed. |
US10843477B2 |
Makeup fluid and inkjet printer apparatus
A makeup fluid is added to an ink liquid of an inkjet printer to reduce the viscosity of the ink liquid, the makeup fluid including a fluorescent color material in a solvent. An inkjet printer apparatus employing a makeup fluid is provided with a makeup fluid tank to which a light-emitting element and a light-receiving element are attached, and detects the presence or absence of the makeup fluid by irradiating ultraviolet light from the light-emitting element, causing visible light to be emitted from the fluorescent color material in the makeup fluid, and detecting the visible light with the light-receiving element. |
US10843476B2 |
Method of manufacturing a liquid cartridge and a liquid cartridge for recycling
A method for manufacturing a liquid cartridge for recycling includes a preparing step and a first step. The preparing step prepares the liquid cartridge for recycling. The liquid cartridge for recycling includes a liquid accommodating portion, a flowing path, a stopper, and a valve. The first step includes a first insertion step, a firs valve open step, a first injection step, a first valve close step, a first removal step, and a first mounting step. The first insertion step inserts an injection member into the stopper. The first injection step injects the liquid into the liquid accommodating portion through the injection member, after the first insertion step and the first valve open step. The first removal step removes the stopper from the opening while the valve is maintained in the closed position after the first valve close step. The first mounting step mounts a new stopper. |
US10843475B2 |
Ink refill container, ink refill system, and ink refill adapter
An ink refill container 63 includes a container main body 64 including an ink storage chamber 76, an ink outlet-forming portion 66 provided on an end portion of the container main body forming an ink outlet 65 that allows the ink to flow out from the ink storage chamber, and a valve 74 provided in the ink outlet-forming portion configured to openably seal the ink outlet, in which the ink outlet-forming portion includes a positioning portion 73 on an outer side of the ink outlet-forming portion. in which the positioning portion 73 is closer to the container main body than the valve 74 is to the container main body in a central axis direction of the ink outlet, and in which the positioning portion partially abuts against an ink tank 41-45 when the valve is opened for refilling the ink to the ink tank, to thereby position the valve relative to the ink tank. |
US10843470B2 |
Inkjet recording method and inkjet recording apparatus
Inkjet recording is performed by using an inkjet recording apparatus including an ink circulation channel for circulating a first ink, an ink supply channel for supplying a second ink into the ink circulation channel, and a recording head communicating with the ink circulation channel. The apparatus is configured to eject an aqueous ink including the first ink and the second ink from the recording head, thereby recording an image on a recording medium. The content (% by mass) of water in the first ink and the content (% by mass) of water in the second ink differ from each other by 2.00% by mass or more. The first ink contains a resin, and the second ink contains a first water-soluble organic solvent having a Log P value of less than −1.10. |
US10843467B2 |
Liquid ejecting apparatus
There is provided a liquid ejecting apparatus including: a print head having an ejection opening surface on which an ejection opening array for ejecting a liquid is provided in a first direction; a cap unit for protecting the ejection opening array; a moving unit configured to relatively move the print head and the cap unit; a first positioning portion for locating the print head and the cap unit in a first relative position where the print head and the cap unit come into contact with each other; and a second positioning portion for locating the print head and the cap unit in a second relative position where the print head and the cap unit come into contact with each other, the second relative position being different from the first relative position. |
US10843464B2 |
Electromechanical transducer element, liquid discharge head, liquid discharge apparatus
An electromechanical transducer element includes an electromechanical transducer film including a complex oxide that has a perovskite structure containing at least Pb, Zr and Ti; a pair of electrodes disposed to sandwich the electromechanical transducer film; and an insulating protective film covering the electromechanical transducer film and the pair of electrodes. Pb content of the electromechanical transducer film is uniform in a film thickness direction of the electromechanical transducer film, and a density of leak current measured between the pair of electrodes is 4.2×10−6 A/cm2 or less in an environment in which a water vapor pressure is 300 kPa. |
US10843463B2 |
Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head that includes a first piezoelectric element and a second piezoelectric element, a first wire that extends in a first direction and that electrically couples the first piezoelectric element and a wiring substrate to each other, and a second wire that is adjacent to the first wire in a second direction intersecting the first direction and that extends in the first direction, the second wire electrically coupling the second piezoelectric element and the wiring substrate to each other. A first protrusion is formed on a surface of the first wire in a mounting area to where the wiring substrate is joined, and a second protrusion is formed on a surface of the second wire in the mounting area and at a position different from that of the first protrusion in the first direction. |
US10843461B2 |
Head holding mechanism and inkjet printer
A head holding mechanism and an inkjet printer are provided. The head holding mechanism includes a head holding member that holds an inkjet head, a carriage side member attached to the carriage and to which the head holding member is fixed, and a fixing member for fixing the head holding member to the carriage side member. The fixing member is movably held by the carriage side member. The fixing member is movable between an engagement position where the fixing member engages with the head holding member to fix the head holding member to the carriage side member, and a disengagement position where the engagement state of the head holding member and the fixing member is released and the head holding member is detachable from the carriage side member. |
US10843460B2 |
Liquid ejection head, liquid ejection device, and liquid ejection method
A liquid ejection head configured to eject a liquid through nozzles includes plural head sections including a first head section and a second head section. Each of the plurality of head sections includes plural nozzle rows. One of the plural nozzle rows of the first head section is supplied with an undercoat-forming liquid containing an undercoat-forming pigment with an average particle diameter of at least 200 nm at a concentration of at least 7 percent by mass. Each of the plural nozzle rows of the second head section is supplied with an image-forming liquid containing an image-forming pigment with an average particle diameter of less than 200 nm at a concentration of less than 7 percent by mass. |
US10843459B2 |
Droplet deposition apparatus and test circuit therefor
A test circuit to determine the capacitance of an actuator element in an actuator element array, wherein the test circuit comprises: a controller; a source to generate test inputs; measurement circuitry to measure one or more test values on a test path between the test circuit and the actuator element; wherein the controller is configured to, for a test period: control a first switch associated with the actuator element to connect the actuator element to the test path; control the source to generate a first test input; and determine a total capacitance of the actuator element from a first test value generated in response to the first test input; and determine the capacitance of the actuator element (CACT) from the total capacitance (CPAR+CACT). |
US10843458B1 |
Method and apparatus for three-dimensional digital printing
Techniques are presented for digital ink jet printing upon a substrate with a significant third dimension. Droplets in the range of 120 pL to 200 pL have been found suitable for substrates with variability, in the third dimension, of up to approximately 4 cm. A larger droplet can be generated by utilizing a plurality of drive pulses, each of which generates a smaller droplet, and having the plurality of smaller droplets combine in mid-air. The data to be printed can be derived from a 3D model and such 3D model can also be used to guide shaping of the substrate. The 3D model can be produced from 2D image data. If the 2D image data is a two-dimensional portrait photograph, a result, of using the present invention, can be a realistic portrait in the form of a bas-relief sculpture. |
US10843457B2 |
Adapting sleeve with hydraulic pads for a flexographic printing machine
An adapting sleeve for flexographic printing machines defines an exterior surface appropriate for the mounting of a printing sleeve. The adapting sleeve has an outer cylindrical member made of a rigid material and surrounding an inner cylindrical member that defines a cylindrical passage for mounting of the adapting sleeve on a rotary core of a flexographic printing machine. The adapting sleeve has some ring separators that are mounted between the outer cylindrical member and the inner cylindrical member and spaced longitudinally from each other. The adapting sleeve has a hydraulic device that includes hydraulic pads arranged between the inner surface of the inner cylindrical member and the ring separators and connected by a hydraulic circuit to a pressurization element that is actionable manually from the exterior of the adapting sleeve. |
US10843455B2 |
Method and apparatus for curing inks printed on heat sensitive absorbent article components
Aspects of the present disclosure relate to methods and apparatuses for printing and curing energy curable inks printed on a substrate having an onset temperature Tonset (C°). The printing systems may include a printing station and a light source. During operation, the printing station deposits energy curable ink onto a first surface of the substrate to define a printed region, and the light source directs ultraviolet light onto the first surface of the substrate to define an illumination zone on the first surface of the substrate. The substrate is advanced in a machine direction to advance the printed region through the illumination zone to cure the energy curable ink. While the printed region advances through the illumination zone, the ultraviolet light heats the substrate from an initial temperature Tin (C°) entering the illumination zone to a maximum temperature Tmax (C°), wherein Tmax (C°)≤Tonset (C°). |
US10843449B2 |
Method and apparatus for forming composite plies on contoured tool surfaces
An end effector transports, places and forms a composite ply on a tool having complex tool surfaces. The end effector includes a combination of vacuum and Bernoulli grippers for holding the composite ply while it is being transported and formed, and a set of mechanical actuators that form the composite ply down over the tool surfaces. The Bernoulli grippers allow the composite ply to slip while being held and formed. |
US10843447B2 |
Heat-sealable and peelable polyester film, use thereof and process for production thereof
A transparent, peelable polyester film is provided with clarity greater than 80% including a biaxially oriented polyester film as base layer (B) and an offline coated heat-sealable outer layer (A) that is peelable relative to ready-meal APET or RPET trays. The heat-sealable and peelable outer layer (A) includes from 85 to 99 wt % polyester and from 1 to 15 wt % other substances, the polyester including of from 25 to 95 mol % of units derived from at least one aromatic dicarboxylic acid and from 5 to 75 mol % of units derived from at least one aliphatic dicarboxylic acid. The polyester incorporates at least 10 mol % of units derived from diols having more than 2 carbon atoms. The mass of the dry outer layer (A) is from 1 to 5 g/m2. Production processes for the foregoing film, and use thereof as scalable film for ready-meal trays is also provided. |
US10843443B2 |
Delamination-resistant heat-shrinkable multilayer oxygen barrier film containing polyester
A first multilayer shrink film has an outer polyester layer, an inner 02-barrier layer, and a tie layer between the polyester layer and the barrier layer. A second multilayer film an outer polyester layer, an inner polyamide layer, and a tie layer between the polyester and polyamide layers. The tie layer comprises a styrene-based polymer, and the tie layer in the second film comprises an anhydride functional styrene based copolymer. Included are a packaging article comprising the film, a packaging process utilizing the film, a process for making the film, and a packaged product comprising a packaging article made the film, with a product inside the package. |
US10843440B2 |
Laminated glazing with recessed very thin interior glass
A laminated glazing includes two sheets of glass and a polymer interlayer positioned between them. The first sheet of glass is thicker than the second sheet of glass the thickness of which is less than 1.2 mm. The edge of the second sheet of glass is recessed with respect to the edge of the first sheet of glass over all or part of the periphery of the glazing, thereby making it possible to protect the more fragile second sheet of glass from mechanical knocks against the edge face of the glazing. |
US10843437B2 |
Carbon-fiber-reinforced thermoplastic-resin composite material and molded body using the same
The invention is intended to obtain a composite material suitable for mass production or the like by shortening the molding time while obtaining the advantages of the composite materials described above, and intended to provide a composite material which has a short molding time by the use of a thermoplastic resin as a matrix and is excellent in balance among stiffness, strength, and thermal conductivity. A carbon-fiber-reinforced thermoplastic-resin composite material comprising: a layer (I) containing a carbon fiber (A) aligned in one direction and a thermoplastic resin (C-1); and a layer (II) containing a carbon fiber (B) aligned in one direction and a thermoplastic resin (C-2), wherein the carbon fiber (A) has a higher elastic modulus than the carbon fiber (B). |
US10843431B2 |
Device for producing pellets
A device for producing pellets has a machine frame, a hollow outer cylinder mounted therein with a first axis of rotation and an inner cylinder, arranged in the outer cylinder, with a second axis of rotation, wherein a wedge-shaped gap is formed between an inner surface of the outer cylinder and an outer surface of the inner cylinder, the outer cylinder and/or the inner cylinder has radial holes for pressing through material, and a pivot arm is arranged on each of the two sides next to the inner cylinder, on which pivot arms the inner cylinder is rotatably mounted. Each pivot arm is moveably mounted on the machine frame in the region of both ends of the pivot arm. |
US10843430B2 |
System for extracting a fluid by suction, and a vehicle with a system of this type
A system includes a vehicle monument, a hose with a fluid line, and an adapter with a triggering unit and a housing, which has a fluid connection. The fluid connection couples to a fluid mating connection, wherein the monument has a fluid main valve and a control unit for controlling the fluid main valve, an inlet of the fluid main valve couples to a fluid suction source, and a first end of the hose connects to the monument such that a first end of the fluid line is coupled to a first outlet of the fluid main valve. A second end of the hose is connected to the adapter such that a second end of the fluid line is coupled to the fluid connection, and the control unit controls the fluid main valve based on a triggering signal from the triggering unit. |
US10843428B2 |
Methods and apparatus for installing a tread ring upon a tire carcass
Exemplary embodiments of the subject invention comprise methods and apparatus for mounting a tread ring onto a tire carcass. Such methods include providing a tire tread ring having opposing side edges, arranging the tread ring in an initial ring arrangement in communication with a pressure source, and expanding the tread ring radially outward from the initial ring arrangement to an expanded arrangement. The pressure source is in communication with an outer side of the tread ring, the tread ring being expanded by applying vacuum pressure along the outer side of the tread ring supplied by the pressure source. Such methods also include inserting a tire carcass within a central opening of the tread ring while in the expanded arrangement, contracting the tread ring into an installed arrangement about an outer surface of the tire carcass, and, releasing the vacuum along the outer side of the tread ring. |
US10843426B2 |
Tire vulcanization mold, tire vulcanization device, and tire production method
A tire vulcanization mold disclosed herein includes sectors 13 divided in a tire circumferential direction and molding a tread portion 1 of a tire, and a pair of upper and lower side plates 11 and 12 molding a sidewall portion 2 of the tire. Mold parting lines 16a and 17a formed by the sectors 13 and a pair of the upper and lower side plates 11 and 12 are located in the tread portion 1 and set to pass a bend point 8c of a surface design in the tread portion 1. |
US10843425B2 |
Process for producing tyres provided with auxiliary components for vehicle wheels
A process for producing tyres with auxiliary components for vehicle wheels is described. The process includes i) covering the external surface of an expandable chamber for tyre vulcanisation and moulding apparatuses with a first substantially cross-linkable polysiloxane composition and ii) covering the radially inner surface of the impermeable elastomeric material layer of the green tyre with a second substantially non-cross-linkable polysiloxane composition. An expandable chamber for tyre vulcanisation and moulding apparatuses and, a process for treating the expandable chamber are also described. |
US10843421B2 |
Repair including a chamfered bracket and a chamfered bracket component for reinforcing a damaged structural element made from composite materials
A repair for a structural element made from a composite material includes a bracket defining a first surface and a second surface. The first surface is adapted for facing the structural element. A chamfer is located on a first end of the bracket. An angle is defined between a plane of the chamfer and a plane of the first surface, the first surface of the bracket being adapted to be disposed adjacent to a side of the structural element. The repair also includes a sealant material between the bracket and the structural element, where the sealant material occupies a space established between the chamfer and the structural element. |
US10843418B2 |
Press for making a part from fiber composite
The invention relates to a press for producing a component from a fibre-composite material, which is designed as a membrane press, comprising a press frame (15), a press lower part (3) on which a mould (4) is arranged, a press upper part (5) having a pressure chamber (6) that can be sealed against the press lower part (3), one or more press cylinders (9) which are supported on the press frame and act on the press upper part (5) and/or the press lower part (3), a membrane (11) that can be tensioned over the mould (4), a vacuum pump (12) with which a vacuum can be generated on a side of the membrane (11), for example on the underside, characterised in that the press frame is designed as a C-frame with an upper horizontal C-arm, a lower horizontal C-frame and a vertical C-base. |
US10843417B2 |
Method and system for resin infusing a composite preform
Resin infusing a composite preform includes locating the preform on an upper tool surface having a resin reservoir element on a downstream side of the composite preform. A vacuum bagging film is placed over the tool surface to cover the composite preform and the resin reservoir element, and is sealed relative to the tool surface to define a sealed resin infusion chamber. A resin supply is provided along with a resin flow path from the resin supply to the resin infusion chamber on an upstream side of the composite preform, through the composite preform and through the reservoir inlet to the resin reservoir. At least partial vacuum pressure applied to the reservoir outlet establishes a pressure differential between the resin supply and reservoir outlet to drive resin from the resin supply through the resin flow path, infusing the composite preform with resin and collecting excess resin in the resin reservoir. |
US10843411B2 |
Method for regulating temperature at a resin interface in an additive manufacturing process
A method for additive manufacturing includes: at a build tray arranged over a build window and containing a resin reservoir of a resin, heating the resin reservoir toward a target bulk resin temperature less than a heat deflection temperature of the resin in a photocured state; at a resin interface between a surface of the build window and the resin reservoir, heating an interface layer of the resin reservoir toward a target reaction temperature; and, in response to the resin reservoir exhibiting a first temperature proximal the target bulk resin temperature and to the interface layer exhibiting a second temperature proximal the target reaction temperature: at the resin interface, selectively photocuring a first volume of the resin to form a first layer of a build adhered to a build platform; and retracting the build platform away from the build window. |
US10843410B2 |
System and method for a three-dimensional optical switch display (OSD) device
The present invention includes a system, apparatus and method for generating a three-dimensional image and/or printing a three dimensional structures, the system comprising: a medium comprising a photocurable monomer and an optical molecular switch molecule that has a non-fluorescent state and a fluorescent state, wherein the monomer forms a polymer upon exposure to the emitted light. Also taught are novel fluorescent photoswitch molecules. |
US10843407B2 |
Three-dimensional printing system
A three-dimensional (3D) printing system including a control module, at least one moving module, a particle-type 3D printing nozzle and a coil-type 3D printing nozzle is provided. The moving module, the particle-type 3D printing nozzle and the coil-type 3D printing nozzle are respectively and electrically connected to the control module, and the particle-type 3D printing nozzle and the coil-type 3D printing nozzle are disposed on the at least one moving module. The control module moves the particle-type 3D printing nozzle or the coil-type 3D printing nozzle through the at least one moving module, and drives the particle-type 3D printing nozzle or the coil-type 3D printing nozzle to perform a 3D printing operation to print a 3D object. |
US10843406B2 |
Additive manufacturing system having multi-flex nozzle
A head is disclosed for use with an additive manufacturing system. The head may include a matrix reservoir, and a plurality of nozzles simultaneously fluidly connected to the matrix reservoir. The head may also include at least one hinge connecting the plurality of nozzles. |
US10843397B2 |
Coextrusion adapter
A coextrusion adapter, including a central conduit having an inlet end and an outlet end and having bottom and top walls that define the height of the central conduit and side walls that define the width of the central conduit, as well as at least one coextrusion conduit having an inlet end and an outlet end. The outlet end feeds into the central conduit near or in the vicinity of the bottom and/or top wall thereof, downstream of the inlet end of the central conduit, and adjusting devices are provided, which are allocated to each outlet end of the at least one coextrusion conduit and are composed of a plurality of adjusting elements, which collectively extend across the width of the outlet end and by actuating drives, are adjustable independently of one another so that it is possible to change the inner width of the respective width section of the outlet end. Adjacent to the outlet end at least one of the side walls has a receiving bore into which it is possible to insert a displacing element that protrudes beyond the side wall into the central conduit. |
US10843387B2 |
Method of manufacturing a press molding
To provide a method of manufacturing a press molding by molding a molding material comprising reinforced fibers and a thermoplastic resin by a cold press method. The method of manufacturing a press molding comprising reinforced fibers and a thermoplastic resin, includes the steps of: holding the molding material heated at a temperature not lower than the softening temperature with a plurality of grippers installed on a carrier; carrying the molding material between the upper mold and the lower mold of a mold for molding; pushing the molding material with pushers to preform it at a predetermined preforming rate; and press molding the preformed molding by closing the upper mold and the lower mold and applying pressure. |
US10843386B2 |
Sheet manufacturing apparatus and sheet manufacturing method
A sheet manufacturing apparatus includes a web forming unit that forms a web in which at least fiber and resin are deposited in the air; a pressing unit that presses the web; and a heating and pressing unit that heats and presses the web on a further downstream side than the pressing unit in a transport direction of the web, in which a pressing force of the pressing unit is greater than a pressing force of the heating and pressing unit. |
US10843375B2 |
Process for producing wood-based OSBs having reduced emission of volatile organic compounds (VOCs)
A process for treating wood strands suitable for producing OSBs includes treating the wood strands in water at a temperature in the range from 50° C. to 100° C. The present invention likewise relates to a process for producing wood-based OSBs, in particular wood-based OSBs having reduced emission of volatile organic compounds (VOCs), including: a) production of wood strands from suitable timbers; b) treatment of at least part of the wood strands with water; c) drying of the wood strands which have been treated with the water; d) coating of the wood strands which have been treated with water and dried and coating of wood strands which have not been treated with water with at least one binder; e) scattering of the glue-coated wood strands on a conveyor belt; and f) pressing of the glue-coated wood strands to give a wood-based OSB. |
US10843373B2 |
Sheet manufacturing apparatus, sheet manufacturing method, resin powder, and sheet
A sheet manufacturing apparatus according to the invention has a mixing unit that mixes fiber and resin powder in air; and a sheet forming unit that forms a sheet by laying and heating the mixture mixed by the mixing unit; the grindability index of the resin contained in the resin powder being 0.8 or less. |
US10843372B1 |
Methods and compositions for preparing particle boards
An amorphous polylactic acid polymer having a weight average molecular weight in the range of about 35,000 to 180,000 is described. The polylactic acid polymer composition can be hammer milled without cryogenics result in the form of particles wherein 90% of the particles have particle size of about 250 μm or less and the material has a glass transition temperature of between about 55° C. to about 58° C. and a relative viscosity of about 1.45 to about 1.95 centipoise. |
US10843371B2 |
Method of making a laminated wood product
The present disclosure relates to a method of producing a laminated wood product, comprising providing a plank presenting a pair of parallel major surfaces, a pair of minor surfaces, a pair of end surfaces and a longitudinal direction parallel with said major and minor surfaces and perpendicular to the end surfaces, said plank having a water content of more than 25% by weight, preferably more than 30% by weight, initializing at least one longitudinal crack in the plank, drying said crack initialized plank to a moisture content of less than 20% by weight, and laminating said crack initialized plank by gluing at least one of its major surfaces to a surface of a second member, thus forming the laminated wood product. The disclosure also relates to a laminated wood product, which may be formed according to the method. |
US10843370B2 |
Sawmill carriage assembly
A method for constructing a lower section of a sawmill carriage assembly comprises holding structural components between a pair of metal plates, and affixing the plates and the structural components together. The structural components may include wheels that guide the sawhead in linear movement along a track on a sawmill bed, to which the carriage base is attached. The structural components may also include a track cleaning system disposed between the metal plates. The track cleaning system maintains optimal track conditions. |
US10843369B2 |
Lightweight chainsaw guide bar
A chainsaw (100) includes a power unit and a working assembly powered responsive to operation of the power unit. The working assembly includes a guide bar (120) around which a chain is rotatable. The guide bar (120) includes a laminated structure in which different ones of the layers of the laminated structure are comprised of different materials. |
US10843368B2 |
Parallel and square alignment tool
An alignment tool is disclosed for connection to a work component and for use in aligning the work component with a work piece to establish a repeatable set up for cutting or routing of the work piece, and wherein the alignment tool provides for parallel and square alignment of the work component relative to first and second edges of the work piece that are perpendicular to each other. Use of the parallel and square alignment tool aligns the work component for an operation parallel to the second edge of the work piece and the operation may be conveniently repeated on further work pieces without need to measure and mark the work pieces. Optional use of first and second parallel and square alignment tools along opposed second and third edges of a work piece that are perpendicular to a first edge provides for greater accuracy for operations having a greater length. |
US10843367B2 |
Machine for cutting sheets by fluid projection
A machine for cutting sheets by fluid projection is provided. The machine has a head displaceable in three dimensions, arranged on a support table for supporting sheets to be cut, in which there is a hole for the passage of the cutting fluid, the support table being formed by a set of rollers distributed in two groups of rollers and which determine therebetween the hole, being arranged at the entrance to the support table feed rollers provided with rotary drive action, between which a step for introducing the sheets is determined, in movement on the support table, while a synchronization belt is arranged in relation to one end of the rollers and has displacement drive action combined with the rotary drive action of the feed rollers. |
US10843364B2 |
Cutting machine as well as method for cutting elastic strings, in particular meat strings
A cutting machine for cutting up pre-compressed meat strands into slices and a method for slicing pre-compressed meat strands, wherein the blade is moved forward in the feed direction to a limited extent after the blade has completely cut off a slice, and is either subsequently or simultaneously moved backward in the transversal direction. In this way, the forward movement of the meat strand to cut off the next slice can be started earlier. |
US10843362B2 |
Apparatus for scanning food products
The apparatus for detecting physical characteristics of food products, such as poultry, meat or fish, includes: a conveyor for transporting the products; a floating belt, located above the conveyor so as to define an analysis zone (Z) therebetween; a first and a second detecting device, located on opposite sides of an advancement path, each adapted to acquire a multiplicity of partial profiles of the products in the analysis zone (Z), a processing unit connected to the first and second detecting devices and including a first shape module configured to determine the conformation of the external surface of a first portion of the product, based on the partial profiles acquired by the first detecting device; and a second shape module (62) configured to determine the conformation of the external surface of a second portion of the product, based on the partial profiles acquired by the second detecting device. |
US10843359B2 |
Connecting cut assembly
The invention relates to a connecting cut assembly for producing connecting cuts in a material web being conveyed. The connecting cut assembly comprises at least one knife device with a cutting knife for cutting engagement with the material web to produce a connecting cut in the material web. Moreover, the at least one knife device has an actuatable cutting knife angle adjusting device for setting a respective cutting knife angle of the cutting knife to the material web. The connecting cut assembly comprises at least one presetting unit for actuating the respective cutting knife angle adjusting device. |
US10843355B2 |
Razor blade, razor head, and method of manufacture
An integrally formed rigid razor blade is provided. The razor blade includes a cutting edge portion extending along a cutting edge portion axis and having a cutting edge at one end, a base portion extending along a base portion axis, and a bent portion intermediate the cutting edge portion and the base portion. The bent portion has an average radius of curvature of between 0.4 millimeters and 1.00 millimeters. The cutting edge portion has a cantilever dimension which is a constant distance of between 1.1 millimeters and 1.8 millimeters when measured from the cutting edge portion to the base portion axis. |
US10843353B2 |
Actuating mechanism for controlling the cutting length of a hair trimmer
The present application relates to an actuating mechanism (2) for controlling the cutting length of a hair trimmer. An actuating mechanism employs a frame (6), an actuator (8), a sliding member (5) and a coupling mechanism (7). The actuator and sliding member are mounted to the frame and are configured to slide linearly relative to the frame. The coupling mechanism connects the actuator to the sliding member and is configured such that sliding the actuator relative to the frame causes sliding movement of the sliding member relative to the frame of a reduced distance. |
US10843351B2 |
Fastener
The first fastener comprises a post, a fifth outer boss, an outer slab, a first hole and a second inner flange. The fifth outer boss is provided in an upper portion of the post. The outer slab perpendicular to the post is provided in a lower portion of the post. The first hole is provided within a local region of the outer slab below the post. The second inner flange is provided on an inner wall of the first hole. The second inner flange has a first gap greater than a width of the fifth outer boss. The upper surface of the second inner flange is used for abutting on a lower surface of a fifth outer boss of a second fastener having a same structure as the first fastener when limiting a position of connected pieces in a height direction of the post. Two sections of the second inner flange and two sections of the first gap are provided on the inner wall of the first hole in a staggered manner. Each section of the second inner flange is equivalent to ¼ of a circumference of the inner wall of the first hole. Each section of the first gap is equivalent to ¼ of the circumference of the inner wall of the first hole. |
US10843347B1 |
Flexible end of arm tool
An end-of-arm-tool (EOAT) can elongate from a retracted position into an extend position to be configured to fit within a space available for contacting and grasping an object. The EOAT includes arrays of linkage elements having corresponding arrays of suction cups attached to linkage element of the linkage element array. In the retracted position, the arrays are pulled away from the distal end of the EOAT to be alongside of a longitudinal rail. In the extended position, a proximal end of the array is moved toward the distal end of the EOAT such that the linkages glide outwardly and linearly to deploy additional suction cups of the suction cup array against the object-to-be-lifted. |
US10843346B2 |
Gripping tool, gripping system, and method for manufacturing gripper
According to one embodiment, a gripping tool includes a gripper. The gripper is flexible. A granular material is provided in an interior of the gripper. The gripping tool grips a workpiece by depressurizing the interior of the gripper in a state in which the gripper is caused to contact the workpiece. At least a portion of the gripper includes a resin member and a fibrous member. The fibrous member is provided inside the resin member. |
US10843345B2 |
Workpiece holding mechanism
A workpiece holding mechanism includes a first and second support having a first and second surface part, third support having a third surface part located closer to second than first surface part and located at a height corresponding to first surface part's lower end, fourth support having a fourth surface part located closer to first than second surface part and located at a height corresponding to second surface's part lower end, a fifth support having a fifth surface part located, at first surface part one end in first direction, closer to second than first surface part and located above third surface part, and a sixth support having a sixth surface part, at second surface part's end portion, closer to the first than second surface part and located above fourth surface part. At least one third and fourth face part includes one face or plurality of faces extending in first direction. |
US10843343B2 |
Access detecting system
A access detecting system comprises an access detector installed at an entrance of a work site including a robot or a machine and configured to detect entry or exit of an object to/from the entrance and to output a first control signal when the object approaches the entrance and a second control signal according to a value obtained by adding or subtracting a count of the entry and a count for the exit and a controller configured to power off, or stop a function of, the robot or the machine upon receiving the first control signal and to re-operate the robot or the machine. |
US10843340B2 |
Protected worker zones around mobile robotic platforms that manufacture aircraft
Mobile robotic platforms include a robotic device and a pair of laser scanners. The robotic device is positioned near a front of the mobile robotic platform while the laser scanners are positioned on the sides of the mobile robotic platform. When the mobile robotic platform is located in a selected position relative to an assembly with the front of the mobile robotic platform facing the assembly, the scanners are set to a scan field area of either a selected area for a safety zone around the sides of the mobile robotic platform or a default area within a predetermined distance from the sides. Upon detection of an intrusion into the scan field area of the laser scanners, the robotic device and/or the mobile robotic platform is stopped to prevent harm to a person whom may have inadvertently intruded into the scan field areas around the mobile robotic platform. |
US10843336B2 |
Magnetic assembly of soft robots with hard components
Reconfigurable soft robotic actuators with hard components are described. Magnetic attraction is used to couple flexible molded bodies capable of actuation upon pressurization with other flexible molded bodies and/or with hard components (e.g., frames and connectors) to form a seal for fluidic communication and cooperative actuation. Pneumatic de-coupling chambers built into the hard components to de-couple the hard components from the magnetically-coupled soft molded bodies are described. The use of magnetic self-alignment coupling and pneumatic de-coupling allows for the remote assembly and disassembly of complex structures involving hard and soft components. The magnetic coupling allows for rapid, reversible reconfiguration of hybrid soft-hard robots for repair, testing new designs, and carrying out new tasks. |
US10843335B2 |
Robot and gear unit
A robot includes a first member, a second member provided rotatably with respect to the first member, a gearing that transmits drive power from one side to the other side of the first member and the second member, the gearing includes an internal gear, an external gear having a flexible barrel portion in a tubular shape with an opening portion in an end part, and rotating about a rotation axis relative to the internal gear, and a wave generator, the wave generator includes a cam having a non-circular outer circumferential surface, and a bearing including an inner ring, an outer ring, and a plurality of balls, the first member includes a counter body provided to face the end part on the opening portion side of the barrel portion, and a first seal member is provided between the outer ring and the counter body. |
US10843332B2 |
Soft exosuit for assistance with human motion
A motion control system includes an actuator having an actuation member, the actuation member having a proximal end attached to the actuator on a first side of a joint and a distal end attached to an anchor element attachment point on a second side of the joint. A first sensor is configured to output signals defining a gait cycle and a second sensor is configured to output signals representing a tensile force in the at least one actuation member. A controller receives the output signals from the sensors and actuates the actuator, during a first portion of the gait cycle, to apply a force greater than a predetermined threshold tensile force to the anchor element attachment point via the actuation member to generate a beneficial moment about the joint and to automatically actuate the actuator. |
US10843326B2 |
Compression-held bracket
A bracket for a board that removably couples to a base. The bracket can include a slot at one end and a compression member at the other end. The slot can fit over the base at a first end of the base and can be removed from that end of the base upon removal of the compression member at the other end of the base. The compression member can be removed against a bias such that the compression member applies a bias to the base when the bracket is coupled to the base, and that bias can be removed so as to allow the removal of the bracket. A pegboard or other type of board can be coupled to the bracket with fasteners or other known means. |
US10843325B2 |
Quick coupling apparatus on instrument handle
Disclosed is an apparatus for use with an instrument handle, the apparatus including a housing, a knob receivable in the housing, the knob having a key hole structure to receive an instrument bulb and neck, a slot in the housing to receive the knob, wherein the knob is pressed into the slot to facilitate installation and removal of the instrument bulb and neck. |
US10843323B2 |
Manual tool capable of unfolding only one work accessory
Disclosed is a manual tool capable of unfolding only one work accessory. The conventional manual tools may bring hidden risk to safety with more than two work accessories that may be unfolded simultaneously. According to the present invention, an associated accessory is arranged for a working state of a first work accessory and a second work accessory to transform from a folding state to an unfolding state; in the folding state where the first work accessory and the second work accessory are both folded, the associated accessory does not prevent any work accessory from unfolding; while in the unfolding state where one of the two work accessories is unfolded and the other one is folded, the associated accessory prevents the other one from unfolding, so as to ensure that only one work accessory can be unfolded during use, and if the unfolded work accessory is left unfolded, the other work accessory cannot be unfolded, thereby eliminating the safety risk caused by unfolding multiple work accessories at the same time. |
US10843321B2 |
Power tool
A power tool includes a tool body, a motor, a handle part, and an elastic member. The tool body extends along the driving axis in the front-rear direction. The motor has a motor shaft. The motor shaft is rotatably supported by the tool body and extends in the front-rear direction. The handle part includes a grip part. The grip part extends in a direction crossing the driving axis. The elastic member is interposed between a rear end portion of the motor shaft and an inner wall surface of the handle part. The elastic member biases the motor shaft and the handle part away from each other in the front-rear direction. |
US10843318B2 |
Fastener driving machine
In order to make it possible to easily carry out filling up of a compressed air to a compression chamber without making a fastener driving machine larger in size, there is provided a fastener driving machine that includes a cylinder that forms a piston chamber defined by a piston and drives a driver blade by the piston. The housing has a cylinder case part for housing a cylinder, and a handle part. A pressure accumulating container is provided on the cylinder. The pressure accumulating container includes a bottom wall portion and a top wall portion. A compression chamber that communicates with the piston chamber is provided therein. |
US10843317B2 |
Driver
A driver including: an ejection part to which a fastener is supplied; a driver blade which moves from a first position toward a second position and drives the fastener into a driven member; and a rack provided to the driver blade. The driver further includes: a rotary component engaging with the rack and moving the driver blade from the second position to the first position; and a lock plate engaging with the rack. The driver blade moves from the second position to the first position while the rotary component rotates once, the rotary component is released from engaging with the rack after the driver blade moves from the second position to the first position, and moves from the first position to the second position, and the lock plate is engageable with the rack when the driver blade stops before reaching the second position from the first position. |
US10843313B2 |
Chuck table mechanism
A combined chuck table mechanism includes a chuck table, an electrostatic attraction section, and a vacuum suction section. The chuck table has a holding surface for holding a plate-shaped workpiece. The electrostatic attraction section has electrodes provided in the chuck table for charging an upper surface, a holding surface, through supply of power and electrostatically attracting the workpiece. The vacuum suction section has a porous portion that is formed to be flush with the upper surface, that communicates with a suction source, and that has fine holes, suction ports. The combined chuck table mechanism further includes a control unit adapted to achieve holding of the workpiece through a combined force by supplying power to the electrodes and a negative pressure to the suction ports. |
US10843312B2 |
Magnetic wand for window blinds
A magnetic wand is used for adjusting window blinds. The blinds include slats and a slat angle adjustment mechanism. The wand includes an upper housing portion and a handle portion. The upper housing portion has a connecting mechanism disposed on one end and a docking area on a second end. The connecting mechanism is adapted to connect the upper housing portion to the window blinds. A first magnetically attractive element is disposed within the docking area. The handle portion has an end shaped to fit within the docking area. The end includes a second magnetically attractive element. The second magnetically attractive element is adapted to releasably couple with the first magnetically attractive element through magnetic coupling, forming a magnetic joint. That magnetic joint is configured to prevent the handle portion from longitudinally rotating independently relative to the upper housing portion. |
US10843307B2 |
Vacuum assembly for chemical mechanical polishing
A method includes depositing a slurry onto a polishing pad of a chemical mechanical polishing (CMP) station. A workpiece is polished and polishing by-products and slurry are removed from the polishing pad by a vacuum head. A CMP apparatus includes a polishing pad configured to rotate during a CMP process. The apparatus also includes a slurry dispenser configured to deposit a slurry onto a polishing surface of the polishing pad. The apparatus further includes a momentum vacuum assembly including a slotted opening facing the polishing surface of the polishing pad. The apparatus also includes a first suction line coupled to an upper portion of the momentum vacuum assembly and leading to a first vacuum source, the first suction line configured to transport polishing products which have been removed from the polishing pad through the slotted opening. |
US10843306B2 |
Printing a chemical mechanical polishing pad
A method of fabricating a polishing layer of a polishing pad includes successively depositing a plurality of layers with a 3D printer, each layer of the plurality of polishing layers deposited by ejecting a pad material precursor from a nozzle and solidifying the pad material precursor to form a solidified pad material. |
US10843299B2 |
Object recognition and presentation for the visually impaired
An apparatus configured to perform object recognition is provided that includes a camera, an assistance feedback device, and processing circuitry. The processing circuitry may be configured to receive the plurality of images from the camera and repeatedly determine characteristic features within the plurality of images and compare the characteristic features within the plurality of images to an object identification dataset to determine object matches for identified objects within the plurality of images. The processing circuitry may be further configured to determine a name for identified objects from the object identification dataset, output, using the assistance feedback device, a position indicator for identified objects, and output the name of identified objects within the assistance feedback device field of view. |
US10843297B2 |
Cleaving thin waters from crystals
A method of creating thin wafers of single crystal silicon, sapphire and similar materials, wherein an ingot of single crystalline material, or a ribbon of single crystalline material is cleaved, in a plane parallel to a surface, with laser light focused to a line in the desired plane of cleavage, near the growing cleavage furrow. The light is of a wavelength that the material is transparent to, but for which the material has strong two- or three-photon absorption. Consequently the light is not appreciably absorbed until it reached the desired focal line. The light is presented in an extremely short pulse, which heats and expands the material at the line focus, before the heat can be dissipated. This expansion creates tangential stresses around the focal line. These stresses are designed to be precisely normal to the growing cleavage furrow. Therefore the stresses are able to induce cleavage in the desired plane, without inducing cleavage in other possible cleavage planes that may happen to intersect with the growing cleavage edge. In this way, extremely thin wafers and ribbon shaped wafers can be produced, with extremely high quality cleaved faces. Methods of initiating the cleavage furrow and separating the cleaved wafer from the rest of the crystal are also discussed. |
US10843296B2 |
Cutting a workpiece
A method for cutting a workpiece includes cutting the workpiece along a predefined cutting contour to separate a workpiece part from a scrap part, and checking whether the workpiece part has been fully separated from the scrap part during the cutting. The workpiece is re-cut along an additional cutting contour laterally offset from the predefined cutting contour if it is found during the checking that the workpiece part has not been fully separated from the scrap part. The disclosure also relates to an associated machine for cutting a workpiece. |
US10843294B2 |
Laser processing apparatus
Provided is a laser processing apparatus comprises a stage holding a substrate, the stage being movable in a first direction, a laser beam source radiating a laser beam onto the substrate, a dust-suction duct having a first optical path extending in a second direction perpendicular to the first direction, the laser beam travelling along the first optical path thereof, and an air aspirator aspirating an air toward a direction opposite to the first direction, wherein the dust-suction duct includes a pair of air-guiding plates opposed to each other along a third direction perpendicular to the first and second directions, and wherein the pair of the air-guiding plates are configured to have a gap therebetween such that it is narrowest in an optical path region and gets wider as it is far away from the optical path region in upstream and downstream regions thereof. |
US10843291B2 |
Welding in preparation for superplastic forming
A component is formed by welding a plurality of sheets of metal to form a blank with a number of weld nuggets, placing the blank between a die section and a lid section, heating the die section to heat the blank, and introducing a pressurized gas between the lid section and the die section to press the blank into a mold in the die section to form a component. The number of weld nuggets has a desired thickness ratio between about 1.1 to about 1.25 such that the plurality of sheets of metal and the component formed have a number of characteristics that are substantially the same. |
US10843290B2 |
Acoustically enhanced optical cables
Methods and apparatus to control the acoustic properties of optical cables used as in-well oil and gas probes for acoustic monitoring, such as distributed acoustic sensing (DAS). One example aspect provides a solid path for the acoustic wave to propagate from an outside armor layer of the cable to the sensing optical waveguide embedded therein. Another example aspect offers ways to spatially dispose the optical sensing elements to create response delays indicative of the propagation speed and/or direction of an acoustic wave. Yet another example aspect provides ways to utilize additional spectral interrogation to increase ultimate spatial resolution. Yet another example aspect provides ways to locally vary the acoustic properties along the length of the cable. |
US10843289B2 |
Devices for feeding electrode capsules
Devices which shorten the time needed for the assembly of electrode capsules on welding grippers are provided. Such devices may have two stations for withdrawal of electrode capsules. The withdrawal stations may have a mirror-image arrangement with respect to a given intermediate plane and may be situated in a peripheral zone of the apparatus. Two guide ducts may house two respective rows of electrode capsules. Two prechambers can be provided, each one being arranged between the associated withdrawal station and an outlet end of the associated guide duct. A retractable stop pin may be mounted between each prechamber and the associated withdrawal station, said pin, when extracted, blocking an electrode capsule inside the withdrawal station. To transfer an electrode capsule from the prechamber to the associated withdrawal station, the apparatus may be provided with two positioning devices which can be selectively operated in order to accomplish this. |
US10843288B2 |
Welding wire feeder power control system and method
A method of operating a welding wire feeder includes receiving an input power signal from a power source and converting the input power signal to a bus power signal on an internal bus at a first time with a boost converter. The method also includes detecting bus voltage and bus current of the bus power signal on the internal bus and converting the bus power signal to a welding output signal at a second time with a buck converter. The welding output signal is suitable for a controlled waveform welding process. The method also includes detecting output voltage and output current of the weld output, and reducing a voltage ripple on the internal bus based at least in part on the detected bus and output current and/or voltages. |
US10843281B2 |
Anti-kickback device
An anti-kickback device is disclosed where the device includes a plurality of flexible members, and at least a compliant contact surface in contact with a moving workpiece, where the flexible members provide a biasing force against the workpiece and also resist or prevent kickback of the workpiece as it engages a tool such as a shaper, saw blade, etc. The configuration of the flexible members assures an opposing force to resist kickback. |
US10843280B2 |
Levelling apparatus for gang saws
A levelling apparatus for use in gang saws comprises first and second wedge portions. The first wedge portion comprises upper and lower surfaces, wherein the lower surface is nonparallel to the upper surface. The first wedge portion further comprises a plurality of openings for accepting mounting fasteners. The openings are arranged in a spaced, circular pattern about a centre of the first wedge portion. The second wedge portion also comprises upper and lower surfaces, wherein the upper surface is nonparallel to the lower surface. The second wedge portion further also comprises a plurality of openings for accepting the mounting fasteners. The second wedge openings correspond to the first wedge openings Rotation of the first wedge portion with respect to the second wedge portion varies an angle between the first wedge upper surface and the second wedge lower surface, thereby allowing for angular adjustment. |
US10843271B2 |
Method for manufacturing a turbine shroud for a turbomachine
The invention relates to a method for manufacturing a turbine shroud (24) for a turbomachine, the method comprising manufacturing at least one turbine shroud sector (28), positioning the turbine shroud sector (26) in a bottom mold so that an outer surface of the turbine shroud sector is in contact at least in part with the bottom mold, and depositing a powder layer on an inner surface (28) of the turbine shroud sector (26). Thereafter, a top mold is positioned on the powder layer and an abradable layer (32) is made by subjecting the powder layer to a method of SPS sintering, the abradable layer (32) being for being disposed facing a turbine wheel. |
US10843270B2 |
Method of fabricating an airfoil preform, an airfoil, and a nozzle sector, by selective melting on a bed of powder
A method of fabricating an airfoil preform for a turbine engine by selective melting on a bed of powder, the preform including an airfoil and a removable support secured to the airfoil, the airfoil being fabricated layer by layer from a first edge to a second edge of the airfoil, the method including fabricating the removable support and the airfoil, the removable support being for securing to a fabrication platform and to a portion of a face of the airfoil situated near the first edge and facing the fabrication platform. The face of the airfoil facing the fabrication platform includes a flat extending away from the face, the flat being present over a portion of the face that is situated outside the first edge, the support being secured to the flat or both to the flat and to the portion of the face that is situated outside the first edge. |
US10843269B2 |
Method of producing sintered and forged member
A method of producing a sintered and forged member includes a mixing process in which a manganese-containing powder made of Fe—Mn—C—Si containing manganese as a main component, an iron powder made of Fe, a copper powder made of Cu, and a graphite powder made of graphite are mixed together to prepare a mixed powder; a molding process in which the mixed powder is compression-molded into a molded product; a sintering process in which, when the molded product is heated, copper derived from the copper powder and manganese contained in the manganese-containing powder are alloyed, the alloyed copper-manganese alloy is brought into a liquid phase state, and the molded product is sintered to produce a sintered product while elements of the copper-manganese alloy diffuse into an iron base of the molded product; and a process in which the sintered product is forged. |
US10843268B2 |
Metal laminated and shaped object, aluminum-based powder for metal laminating and shaping, and method of manufacturing the same
The present invention provides a robust metal lamination-shaped object containing aluminum and having no defect. A metal powder used for forming this metal lamination-shaped object is an aluminum-based powder having a volume-based 50% particle diameter larger than or equal to 10 μm and smaller than 100 μm when a particle diameter distribution is measured by a laser diffraction-scattering method, a specific surface area smaller than or equal to 0.5 m2/g, and an oxygen amount larger than or equal to 3 mg/m2 and less than or equal to 10 mg/m2 per unit surface area. A relationship between a hydrogen amount (X ml in standard state) per 100 g of the aluminum-based powder and a specific surface area (Y m2/g), and a relationship between the hydrogen amount (X ml in standard state) and an oxygen amount (Z wt %), are respectively in accordance with formulas: X/Y<151 and Z/X>0.0022. A metal lamination-shaped object, that is lamination-shaped by a three-dimensional lamination-shaping apparatus in a powder bed fusion type using the above metal powder, has a hydrogen amount less than or equal to 3 ml in standard state per 100 g, and a relative density more than or equal to 99%. |
US10843267B2 |
Additively manufactured heat exchangers
Heat exchangers are manufactured by three-dimensional (3D) printers by printing subsequent layers of a material in a print direction. The heat exchangers include one or more tubes. The one or more tubes are configured to transport a fluid to be heated or cooled. Each of the one or more tubes defines a slope that is within a threshold angle of the print direction. The heat exchangers include a plurality of fins that are each configured to intersect with the one or more tubes while allowing fluid flow between the plurality of fins to heat or cool the fluid. Each fin of the plurality of fins defines a slope that is within a threshold angle of the print direction. |
US10843262B2 |
Compositions comprising eutectic metal alloy nanoparticles
Provided herein is a composition for eutectic metal alloy nanoparticles having an average particle size ranging from about 0.5 nanometers to less than about 5000 nanometers and at least one organoamine stabilizer. Also provided herein is a process for preparing eutectic metal alloy nanoparticles comprising mixing at least one organic polar solvent, at least one organoamine stabilizer, and a eutectic metal alloy to create a mixture; sonicating the mixture at a temperature above the melting point of the eutectic metal alloy; and collecting a composition comprising a plurality of eutectic metal alloy nanoparticles having an average particle size ranging from about 0.5 nanometers to less than about 5000 nanometers. Further disclosed herein are hybrid conductive ink compositions comprising a component comprising a plurality of metal nanoparticles and a component comprising a plurality of eutectic metal alloy nanoparticles. |
US10843258B2 |
Multi-chamber molten metal pump
In accordance with one aspect of the present exemplary embodiment, a molten metal pump comprising a refractory material body defining an elongated chamber is provided. The chamber is configured to receive a shaft and impeller assembly. The chamber includes an open top through which the shaft passes and a bottom inlet. The impeller is located in or adjacent the inlet. The body further defines an elongated passage adjacent to the chamber. An opening provides fluid communication between the elongated passage and the elongated chamber. The elongated passage is in fluid communication with a discharge channel configured to direct molten metal at least substantially perpendicular to an elongated axis of the elongated chamber. |
US10843257B2 |
Method for manufacturing a part out of a metal matrix composite material, and related device
A method (S) for manufacturing a part (1) out of a metal matrix composite material, including the following steps: opening (S1) a device (10) that includes a supporting portion (14) and a molding portion (14); placing (S2) a fibrous reinforcement into the device (10); sealably closing (S3) the device (10) by providing a space between the fibrous reinforcement (2) and the device portions; feeding (S4) the molten metal matrix (3) into the device (10) such as to fill the space between the fibrous reinforcement (2) and the device portions (13, 14); and applying (S5) a force onto the equipment (10) such as to impregnate the fibrous reinforcement (2) with the metal matrix (3). |
US10843254B2 |
Hot forming of cooling galleries in steel pistons
A piston, particularly a piston for use in a diesel engine, particularly a heavy duty diesel engine, is formed from a billet of metal, such that the finished piston has a mass that is at least 50%, and, more preferably, up to about 62%, of the mass of the billet. Other than finishing steps, the piston is formed with a closed gallery, without loss of mass through machining processes. |
US10843252B2 |
Metal sheet storage device and metal sheet processing device comprising a metal sheet processing machine and a metal sheet storage device of this type
The invention relates to a metal sheet storage device (21) with a housing (22), having a housing upper face (23), and with two support devices, each of which has a support plane (35, 45) for supporting metal sheets (17) or bending parts (19). The support planes (35, 45) of the support devices can be moved relative to the housing upper face (23) of the housing (22) of the metal sheet storage device (21). The invention further comprises a bending device with a bending press and such a metal sheet storage device (21). |
US10843250B2 |
Smart installation/processing systems, components, and methods of operating the same
A processing system employs a processing tool to process workpieces, for example cold working holes and/or installing expandable members into holes. Sensors sense various aspects of the processing. Information regarding performance of the process and/or materials may be stored, for example a hole-by-hole or a workpiece-by-workpiece basis, allowing validation of processing. Information also allows dynamic operation of the processing tool. Analysis of response relationships (e.g., pressure or force versus position or distance) may provide insights into the process and materials, and/or facilitate the real-time feedback including control, alerts, ordering replacement for consumable components. |
US10843247B2 |
Material property value estimating method, material property value estimating device, and steel-strip manufacturing method
A material-property-value estimating method of estimating a material-property-value of a target steel-strip product manufactured via at least one of a reheating process, a rolling process, and a cooling process, which are performed while a target material is being conveyed along a conveyance route, the material-property-value estimating method includes an estimating step of estimating a material-property-value of each of meshes dividing the target steel-strip product based on a measured value that has been measured once or more by a measuring device installed on the conveyance route, the measured value including at least a temperature of the target material; and a chemical composition per component of the target steel-strip product. |
US10843241B2 |
Method and system for in situ treatment of water or soil
A method and system for the in situ treatment of at least one contaminant in soil or water is disclosed herein. The method comprises placing an opening into the soil and into at least a portion of subsurface water and thereby filling at least a portion of the opening with the water, placing a reactant in the opening, and moving a portion of the water proximate the bottom of the opening toward the water proximate the top of the opening, thereby increasing the homogeneity of the reactant in the water. |
US10843238B1 |
Hole cleaning apparatus
A hole cleaning apparatus is disclosed. The apparatus comprises an elongated member, a looped member, a hook type fastener member and a plurality of cleaning members. The looped member extends from the elongated member and the hook type fastener member extends from the looped member. The looped member comprises a loop to detachably receive at least one of a plurality of cleaning members and the hook type fastener member fastens the looped member to the elongated member. The looped member and the hook type fastener member are configured to securely hold the cleaning member in place. The elongated member, looped member and hook type fastener member form a unitary body. The hole cleaning apparatus is configured to detachably couple with a rotary drive member to provide rotational motion. The rotary drive member is configured to rotate the plurality of cleaning members to clean a hollow object. The rotary drive member could be any device configured to provide rotational motion. The apparatus could be used in paint body shops, machine shops, automotive shops, millwrights, chemical plants, power plants and various manufacturing fields, and by end users such as mechanics, maintenance personnel, plumbers, etc. |
US10843227B2 |
CMOS ultrasonic transducers and related apparatus and methods
CMOS Ultrasonic Transducers and processes for making such devices are described. The processes may include forming cavities on a first wafer and bonding the first wafer to a second wafer. The second wafer may be processed to form a membrane for the cavities. Electrical access to the cavities may be provided. |
US10843224B2 |
Plasma deposition method for catechol/quinone functionalised layers
A solvent-free plasma method for depositing an adherent catechol and/or quinone functionalised layer to an inorganic or organic substrate from a precursor which comprises at least a quinone group; a protected or unprotected catechol group; a molecule substituted by a quinone group and/or a protected or unprotected catechol group; and/or a natural or synthetic derivative of a catechol group and/or a quinone group; wherein the quinone group is a 1,2-benzoquinone group and the catechol group is a 1,-dihydroxybenzene group. |
US10843221B2 |
System and method for a coating device
A rotatable tool assembly including a motor and a tool assembly operatively coupled to the motor. The tool assembly includes an epicyclic gear system rotatably coupled to the motor and one or more tools rotatably coupled to the epicyclic gear system. The motor is configured to rotate the epicyclic gear system, and the epicyclic gear system is configured to rotate the tool. |
US10843217B2 |
Pump overtubes and methods of making the same
A pump system (100) including an overtube adapter (140) and an overtube (150) attached to the overtube adapter (140), the overtube (150) capable of being selectively attached to the overtube adapter (140) to provide different overtube (150) aesthetics for pump systems and fragrance products. |
US10843213B2 |
Fluid dispensing meter authorization
A fluid management system includes an authentication device and a fluid dispensing meter, and the fluid dispensing meter includes a processor and a memory. The authentication device is configured to provide data to the processor. The processor is configured to recall information from the memory, to compare the information to the data received from the authenticator, and to control a trigger control mechanism between the activated state and the deactivated state based on the comparison. |
US10843207B2 |
Method and apparatus for removal of sea lice from live fish
A fish delousing installation includes a warm water source, and a fish slide for fish to slide down. The fish slide has a fish inlet, a fish outlet, and a slide length defined therebetween. A plurality of shower nozzles are in communication with the warm water source and are positioned to shower the fish with warm water as the fish slide from the fish inlet to the fish outlet. |
US10843204B2 |
Modular shredder and grinder apparatus
A modular shredder and grinder apparatus includes a grinder assembly that has a grinder shaft assembly. The grinder assembly has a grinder opening and a shredder assembly movable with respect to the grinder opening to allow access to the grinder shaft assembly. Scrap material is first fed into the shredder assembly so that shredded scrap material is received through the grinder opening and further cut by the grinder shaft assembly. |
US10843203B2 |
Viscous food product grinding and dispensing system
A viscous food product dispensing system having a transport section for receiving a particulate food product from a bin, an auger for processing and conveying the received particulate food product from the transport section into an outlet adapter via one or more flutes, a milling device housed in the outlet adapter, and a discharge nozzle in the outlet adapter that pinches off the viscous food product created by the milling device. The auger has a unique design that allows it to engage and break whole nuts. |
US10843191B2 |
Molecule detecting system
An object is to stably, continuously and easily detect reactions of filamentary biomolecules or polymers bridging between a pair of electrodes against reagents without employing any marker or labeling substances. A molecule detecting system for detecting a reaction of a molecule captured between electrodes to a reagent in a liquid 37, the system comprising: a detection device including a couple of electrodes and being capable of measuring a resonance frequency and an amplitude of the electrodes; a microfluidic device 30 including a microfluidic channel 36 which includes a channel opening 36c on its one side, wherein an air-liquid interface the electrodes can pass through is formed in the channel opening 36c; a pressure controlled microfluidic pump 33 connected to an outlet 36b of the microfluidic channel 36; a movable holding device movably holding the detection device or the microfluidic device 30; and a controller controlling the detection device, the pressure controlled microfluidic pump 33, and the movable holding device. |
US10843189B2 |
Methods and apparatus for cell culture array
Methods and systems are described for improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays. |
US10843188B2 |
Integrated system for processing microfluidic samples, and method of using the same
This patent application describes an integrated apparatus for processing polynucleotide-containing samples, and for providing a diagnostic result thereon. The apparatus is configured to receive a microfluidic cartridge that contains reagents and a network for processing a sample. Also described are methods of using the apparatus. |
US10843183B2 |
Isolation device with built-in particle counter
An isolation device for supplying a workspace with clean air resulting from dust filtration by an air cleaning means accurately manages the number of fine particles in a workspace and prevents fine particles from mixing with an experimental material. The isolation device includes a measurement probe; a particle counter for measuring the fine-particle counts for a plurality of particle sizes in the workspace air and outputting the measurements; a storage unit for storing, for each of the plurality of particle sizes and for work times and non-work times, management fine-particle counts at which the number of fine particles per unit volume is determined to be large; a cleanliness determination unit that compares the fine particle counts and the management fine-particle counts; and an output unit for outputting an alarm when the work-time/non-work time fine particle count for a particle size in the workspace exceeds the corresponding management fine-particle count. |
US10843182B2 |
Composite material comprising porous silicate particles and active metals
Provided is a composite material including a plurality of porous silicate particles having a glass phase structure, a first active metal adsorbed into the glass phase structure of the porous silicate particles, and a modified layer containing a second active metal formed on the surfaces of the porous silicate particles. The porous silicate particles have an average pore diameter of from 3 nm to 50 nm, and the first active metal includes at least one of sodium, potassium, calcium, and magnesium. |
US10843181B2 |
Method of making a fluoride functionalized zeolite catalyst and method of use
A method for producing a fluoride functionalized zeolite catalyst is described, having a F/Si molar ratio of 0.1:1-3:1. The method involves mixing a fluoride salt with zeolite components to form a gel, which is then hydrothermally treated and calcined. The fluoride functionalized zeolite catalyst may be used for cracking an olefin stream into ethylene, propylene, and butylene, with high selectivity towards propylene. The fluoride functionalized zeolite catalyst may be used for 50 or more hours with a stable conversion rate and low coke formation. |
US10843179B2 |
Self-assembled catalysts and use thereof in olefin polymerization
The present invention relates to a self assembled catalyst. More particularly, the present invention relates to a self-assembled catalyst of formula (I) comprising supramolecular phosphine and carboxylate ligands, process for preparation thereof and use of said catalyst of formula (I) in olefin polymerization. |
US10843174B2 |
Catalyst manufacturing method
A method for producing a catalyst or catalyst precursor is described including: applying a slurry of a particulate catalyst compound in a carrier fluid to an additive layer manufactured support structure to form a slurry-impregnated support, and drying and optionally calcining the slurry-impregnated support to form a catalyst or catalyst precursor. The mean particle size (D50) of the particulate catalyst compound in the slurry is in the range 1-50 μm and the support structure has a porosity ≥0.02 ml/g. |
US10843173B2 |
Ferrite catalyst for oxidative dehydrogenation, method of preparing ferrite catalyst, and method of preparing butadiene using ferrite catalyst
A ferrite catalyst for oxidative dehydrogenation and a method of preparing the same. The ferrite catalyst is prepared using an epoxide-based sol-gel method, wherein a step of burning includes a first burning step, in which burning is performed at a temperature of 70 to 200° C.; and a second burning step, in which burning is performed after the temperature is raised from a temperature in the range of greater than 200° C. to 250° C. to a temperature in the range of 600 to 900° C. |
US10843171B2 |
Zoned diesel oxidation catalyst
An oxidation catalyst is described for treating an exhaust gas from a diesel engine, which oxidation catalyst comprises: a substrate; a first washcoat region disposed on the substrate, wherein the first washcoat region comprises a first platinum group metal (PGM) and a first support material; a second washcoat region adjacent to the first washcoat region, wherein the second washcoat region comprises a second platinum group metal (PGM) and a second support material; a third washcoat region disposed on the substrate, wherein the third washcoat region comprises a third platinum group metal (PGM) and a third support material; and wherein either: (i) the third washcoat region is adjacent to the second washcoat region; or (ii) the second washcoat region is disposed or supported on the third washcoat region. Also described are uses and methods involving the oxidation catalyst. |
US10843170B2 |
Superabsorbent polymer and preparation method thereof
A superabsorbent polymer having high centrifuge retention capacity and absorption rate prepared by using a particular foam stabilizer and a polymerization initiator. The foam stabilizer includes a sucrose ester and a polyalkylene oxide, and polymerization initiator includes a photoinitiator and a cationic azo-based initiator. |
US10843165B2 |
Functionalized chromatographic materials and methods of making and using therefor
Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media. |
US10843161B2 |
Laminated, leak-resistant chemical processors, methods of making, and methods of operating
The invention provides methods of making laminated devices (especially microchannel devices) in which plates are assembled and welded together. Unlike conventional microchannel devices, the inventive laminated devices can be made without brazing or diffusion bonding; thus providing significant advantages for manufacturing. Features such as expansion joints and external welded supports are also described. Laminated devices and methods of conducting unit operations in laminated devices are also described. |
US10843159B2 |
Apparatus for a mass production of monodisperse biodegradeable polymer-based microspheres and a multi-channel forming device incorporatable therein
Provided is an apparatus for a mass production of microspheres and a multichannel forming device incorporatable therein. The apparatus comprises a multi-channel microsphere forming unit, a first source material reservoir containing the first source material and in fluid communication with the plurality of first microchannels, a second source material reservoir containing the second source material and in fluid communication with the plurality of second microchannels, a flow control unit configured to supply a first gas to the first source material reservoir at a first source material flow rate and to supply a second gas to a second source material reservoir at a second source material flow rate and a product reservoir for accommodating the microspheres formed from the multi-channel forming unit. |
US10843158B2 |
Filtering and distribution device for catalytic reactor
The present invention concerns a device for filtration and distribution of a gaseous phase and a liquid phase, which can be disposed upstream of a fixed catalytic bed of a reactor operating with a descending co-current of gas and liquid, comprising: a solid plate on which substantially vertical risers are fixed, said risers are open at their upper and lower ends and have openings over at least a fraction of their height; a plurality of removable baskets capable of retaining at least one filtration medium, each removable basket being defined by an ellipsoidal vertical wall or by at least three vertical lateral walls and a bottom, the vertical walls and/or the bottom being permeable to a gas and to liquid. Each basket is provided support means cooperating with a riser of the plate in order to support the basket. |
US10843150B1 |
System, method and apparatus to facilitate mixing of colours to achieve desired colour consistency
Method, system, and apparatus to facilitate mixing of at least one colour to achieve a desired colour consistency to perform one or more activities. Particularly, the present system includes multiple user devices, a cloud server, and a colour mixing dispensing apparatus. In operation, multiple user devices are accessible to a user via a user interface to input data by the user to select at least one colour coding parameter. The cloud server includes at least one memory adapted to store data for the at least one colour coding parameter in a colour database and at least one processor that is adapted to execute processor-executable code. In practice, the colour mixing dispensing apparatus is configured to provide instant colour mixing to the user by receiving a set of instructions from the cloud server via a communication network. |
US10843148B2 |
Integrated electrowetting nano-injector and aspirator
A new simple transfection method using an integrated electrowetting nano-injector (“INENI”) with controlled dosage delivery and high transfection efficiency is disclosed. The volume of delivery can be controlled via voltage application to an inner and outer electrode integrated into a nano-pipette. With higher voltages, more liquid enters the INENI and with lower voltages liquid is expelled. This method can be used to deliver plasmid DNA directly into the nuclei of cells. The INENI requires only the use of a single probe since both electrodes are integrated into the same nano-pipette. Hence, more space is available, and ergo the INENI offers a simplistic means for direct injection of metered amounts of exogenous material into the confines of a cell cytoplasm and/or nucleus while retaining full cell viability. |
US10843145B2 |
Method and device for production of graphene or graphene-like materials
A method and a device for the production of graphene or graphene-like material are provided. The method can comprise the following steps: providing particles of a crystalline graphitic material; dispersing the particles in a solvent or surfactant mixture; submitting the mixture to a cavitation force such that cavitation bubbles are present; and submitting the mixture to high shear agitation. The cavitation and high shear agitation steps can be simultaneous, in particular in the same enclosed vessel. The device for the production of graphene or graphene-like material can comprise a reactor having an enclosed vessel for receiving a solvent or surfactant mixture with dispersed particles of a crystalline graphitic material. The reactor can be arranged for: submitting the mixture in the enclosed vessel to a cavitation force such that cavitation bubbles are present and, simultaneously in the same enclosed vessel, submitting the mixture to high shear agitation. |
US10843144B2 |
Process for production of elastomer agglomerate composition, elastomer agglomerate composition and its use
The invention relates to a process for the production of an elastomer agglomerate composition, comprising: forcing a slurry through an aperture in a valve assembly (1) to obtain the elastomer agglomerate composition; wherein the valve assembly (1) comprises the valve (2) and a seat (3) that are arranged opposite each other to provide a flow channel for the slurry to be homogenized with an emulsifying channel section (5) that is provided with the aperture; wherein the emulsifying flow channel section is arranged at an angle (a) with respect to an axial center line of the valve in a cross sectional view of the valve assembly; and wherein the slurry comprises elastomeric particles in water. |
US10843140B2 |
Water aeration system with floating diffuser
A water aeration system powers an air pump held in an encasement with a solar panel mounted directly or indirectly to the encasement or to the mounting pole supporting the encasement above a ground surface. An air conduit directs pumped air to one or more disc diffusers submerged in the body of water to be aerated. The disc diffuser(s) are supported by a floating platform that is suspended from a buoy or float so that the disc diffuser(s) are held at a desired depth below the water surface. |
US10843138B1 |
Cellulose acetate V/ZN photocatalytic material
Photocatalytic materials with a composite photocatalyst of a metal oxide impregnated with elemental metal particles, can be embedded into a hydrophilic polymer having pores with diameters of less than 2 nm, to provide a useful water remediation and/or purification product. The metal oxide may be WO3, CeO2, Bi2O3, NiO, TiO2, and/or ZnO, and the elemental metal particles, impregnated or compounded into the metal oxide, may be Fe, Co, Ni, Cu, Ag, Ce, Mn, Mo, V, Bi, Sn, W, Nb, Pd, and/or Pt. The photocatalytic materials may be easily removed and/or retrieved after use, and can effectively combat both chemical and biological contamination and/or fouling of water as well as the membranes composed of the photocatalytic material. |
US10843136B2 |
Selectively permeable membrane devices
A selectively permeable membrane device for separating a first fluid from a second fluid in a flow can include a membrane conduit configured to receive the flow and to allow permeation of the first fluid therethrough, and configured to not allow permeation of the second fluid. The device can include a residence time enhancing structure disposed within the membrane conduit and configured to increase residence time of the flow within the membrane conduit. |
US10843134B2 |
Use of surface modified porous membranes for fluid distillation
In some embodiments, the present disclosure pertains to systems and methods for distilling a fluid by exposing the fluid to a porous membrane that includes a surface capable of generating heat. In some embodiments, the heat generated at the surface propagates the distilling of the fluid by converting the fluid to a vapor that flows through the porous membrane and condenses to a distillate. In some embodiments, the surface capable of generating heat is associated with a photo-thermal composition that generates the heat at the surface by converting light energy from a light source to thermal energy. In some embodiments, the photo-thermal composition includes, without limitation, noble metals, semiconducting materials, dielectric materials, carbon-based materials, composite materials, nanocomposite materials, nanoparticles, hydrophilic materials, polymers, fibers, meshes, fiber meshes, hydrogels, hydrogel meshes, nanomaterials, and combinations thereof. Further embodiments pertain to methods of making the porous membranes of the present disclosure. |
US10843130B2 |
Method and system for controlling mercury emissions from coal-fired thermal processes
The present disclosure is directed to the use of elemental or speciated iodine and bromine to control total mercury emissions. |
US10843123B2 |
Dual system process for ammonia vapor recovery
A method for recovering ammoniacal nitrogen, in the form of ammonium carbonate and/or ammonium bicarbonate, from an ammoniacal nitrogen-containing vapor that comprises introducing said vapor into at least one pressurizable ammonia scrubbing vessel containing water, simultaneously introducing a carbon dioxide-containing vapor into at least one pressurizable carbon dioxide scrubbing vessel containing water, and simultaneously pumping the solutions created in said scrubbers via hydrologic connections between said scrubbers to mix the solution to create an ammonium carbonate and/or ammonium bicarbonate containing mixture, all while maintaining independent and unmixed vapor streams throughout the entire process. The method further involves recovering ammonium carbonate and/or ammonium bicarbonate from the mixture for further use. |
US10843117B2 |
Active carbon filter for a carbon canister and a method for producing the same
A method for producing an active carbon filter for a carbon canister includes defining a body having a honeycomb structure with a plurality of bleed passages from a polymer based material, and forming an adsorption layer along a surface of the body, where the adsorption layer is made of a carbon based material. |
US10843116B2 |
Method and device for reducing a flow of soil air to indoor air in a building
The present invention relates to a method for reducing a flow of soil air to the indoor air in a building (1), wherein the building comprises at least one wall (2), which wall comprises a permeable channel (23) connected with soil air, wherein the method comprises achieving a flow stop (24) for the soil air in the permeable channel (23). The invention also pertains to a device to reduce the flow of soil air to indoor air in a building (1). |
US10843111B2 |
Process of separating blood plasma/serum from whole blood
The invention relates to whole blood filter media and a process of filtering whole blood samples using a filter medium comprising particles, wherein the blood cells are retained inside the filter, and wherein the plasma or serum is separated from the blood cells. |
US10843104B2 |
System and process for biopolymer chromatography
A chromatography system for separation of a biopolymer is described, comprising at least one feed tank, at least one hold tank, at least one elution buffer tank, at least one eluate tank, at least two packed bed chromatography columns and at least one pump and at least one outlet detector both fluidically connected to said each packed bed chromatography column, wherein the feed tank, the hold tank(s), the elution buffer tank and the eluate tank are each fluidically connected to the packed bed chromatography columns via a system of valves. |
US10843093B1 |
Ride systems having dynamic ride vehicle movement
A ride system includes ride vehicles. Each ride vehicle includes a rider support configured to carry a rider, a support actuator coupled to the rider support and a base of the ride vehicle and configured to move the rider support relative to the base, and a ride vehicle movement system integrated with the base and configured to move the ride vehicle relative to a ride area. The ride system also includes a controller configured to control the support actuator and the ride vehicle movement system of each ride vehicle individually based on a choreographed routine and an input received from a selected ride vehicle. The input is indicative of an adjustment to the support actuator, the ride vehicle movement system, or both, of each ride vehicle. The input is based on a correlative adjustment to the support actuator, the ride vehicle movement system, or both, of the selected ride vehicle. |
US10843080B2 |
Automated program synthesis from natural language for domain specific computing applications
Disclosed are various embodiments for automated program synthesis from a natural language for domain specific computing applications. In one embodiment, a natural language processor may be configured to parse words from a sentence of text formed in a natural language, such as English, following a grammatical structure for the natural language. The words may be compared to a dictionary to identify a token. The text formed in the natural language may be converted to an intermediate format of programming code in a programming language, such as C, where the intermediate format includes the token. The token may invoke a function or a routine of a library written in the programming language. The intermediate format may be compiled into executable program code to generate an application, such as a video game, for execution. |
US10843078B2 |
Affect usage within a gaming context
Mental state data is collected as a person interacts with a game played on a machine. The mental state data includes facial data, where the facial data includes facial regions or facial landmarks. The mental state data can include physiological data and actigraphy data. The mental state data is analyzed to produce mental state information. Mental state data and/or mental state information can be shared across a social network or a gaming community. The affect of the person interacting with the game can be represented to the social network or gaming community in the form of an avatar. Recommendations based on the affect resulting from the analysis can be made to the person interacting with the game. Mental states are analyzed locally or via a web services. Based on the results of the analysis, the game with which the person is interacting is modified. |
US10843074B2 |
Object movement control apparatus, storage medium storing object movement control program, and object movement control method
A game apparatus includes an LCD, and a touch panel is provided in relation to the LCD. The LCD displays a game screen, and the player performs touch operations (sliding, click, etc.) on the touch panel with use of a stick to draw, correct and decide at random a moving path of an object. When the movement path of the object is decided and some point on the movement path is clicked, the object moves to the clicked position according to the movement path. |
US10843069B2 |
Input apparatus for a computer
The invention provides an apparatus for supplying user inputs to a computer program, a games controller and an actuator mounted to a controller. The apparatus comprises a case having a first part and a second part. Each of the first and second parts comprise one or more controls. One of the first and second parts comprises a sensor for determining the position of the first part relative to the second part, wherein the position of the first part relative to the second part provides an input control device. |
US10843060B2 |
Systems and methods for ball location on a sports field
Systems and methods for ball location on a sports field may include a plurality of soil moisture sensors distributed on the sports field, such as on a golf course. Each of the soil moisture sensors has a location on the sports field known to the system, and a ball detector that detects a ball being within proximity to the soil moisture sensor. This may be accomplished via one or more of a magnetometer, vibration detector and motion sensor of the soil moisture sensor. The system may use signals from the soil moisture sensors indicating such information to provide information to one or more players regarding a game score and/or other game play statistics based on the ball being within proximity to one or more particular soil moisture sensors. |
US10843059B2 |
Golf swing training device
A golf swing training device including a hinge interposed between two elongated members. The hinge permits the elongated members to selectively break from longitudinal alignment along a first axis with the first elongated member when a prescribed differential force between the first elongated member and the second elongated member is applied to break the longitudinal alignment. The golf swing training device includes a club head including a club head face and a hosel, wherein the hosel is configured to receive an end of the second elongated member. The hosel includes a face angle adjustment mechanism having a plurality of settings to adjust a club face angle of the club head relative to one or more axes of the hinge assembly. A fastener is configured to releasably secure the club head through the hosel to one of the elongate members. |
US10843053B2 |
Golf club with cartridge
A golf club comprising a head having a series of tracks within a cartridge that's removable from the inside of the club head, which forms a three-dimensional pattern; a plurality of weights for positioning along the channels of the cartridge, and a mechanism for securing the weights at arbitrary positions along the channels within the cartridge, so as to customize at least one of center of gravity and moment of inertia from the crown or sole of the club head. The channels can all interconnect with one another to allow a weight to be moved from one to another. The golf club can further have an articulating cover for at least a portion of the surface, the cover being for covering and concealing the cartridge situated within the club head and the weights therein, positioned along the channels thereof. |
US10843050B2 |
Multi-material iron-type golf club head
A multi-material iron-type golf club head having a shell that defines a closed internal volume, where the head is composed of at least two different materials, incorporates a variable face thickness, and achieves a high characteristic time. |
US10843035B2 |
Exercise ring for improving strength and flexibility of a body part
An apparatus and method may exercise muscles of a body part, especially the neck, waist, torso, legs, and glutes from any angle with variable resistance while taking up minimal floor space. The apparatus may improve the ability of athletes, including football players and wrestlers, to better prepare for contact from any angle while engaged in their sport. The apparatus may include a ring having a guide track therein. Another inner ring may also be provided in different sizes and shapes to accommodate a variety of users. A car may be connected to a source of resistance ride freely along the guide track. The source of resistance may be other gym equipment including a bungee cord, a cable cross over machine, springs, and the like. As the user freely exercises by moving the body part, the car may adapt to the user's position to facilitate a full range of motion. |
US10843032B2 |
Bilateral hand rehabilitation device and system
A bilateral hand rehabilitation device is disclosed. The device includes a pair of left and right handlebar members that are fixedly coupled or connected together. The device further includes a pair of moveable left and right finger grip members, one for each of the handlebar members. Each finger grip member being elongate and having a longitudinal axis that is substantially parallel to the longitudinal axis of its respective handlebar member, and each finger grip member being moveably mounted with respect to its respective handlebar member for movement toward and away from the handlebar member to facilitate a user finger grasp and release movement when in use. The device further includes an asymmetric connection mechanism that operatively couples the pair of finger grip members to each other for simultaneous asymmetric movement of the finger grip members such that the movement of one finger grip member toward or away from its respective handlebar member causes the other finger grip member to move in the opposite direction away or toward its respective handlebar member. |
US10843031B1 |
Handlebar assembly for exercise machine
The present invention relates to an adjustable handlebar for an exercise machine. The handlebar is movable between a plurality of orientations when unlocked, and is held in a substantially secure position when locked. The handlebar generally includes a support attached to the machine. A bar assembly with a handle is slidably disposed through an opening in the support. The adjustable handlebar includes first and second locking devices. An upper portion of the bar assembly is rotatable when a first locking device is unlocked and substantially not rotatable when the first locking device is locked. When both the locking devices are unlocked, the bar assembly is longitudinally slidable for adjusting the height of the handle. When either locking device is locked, the assembly is substantially not slidable. |
US10843019B2 |
Branch tee for sprinkler pipes controlling water stream automatically and sprinkler pipe system having the same
Provided are a branch tee for sprinkler pipes, which is capable of selectively sprinkling fire extinguishing water only on a fire occurrence area and preventing the skipping effect although there are many obstacles to sprinkling water or a distance between sprinkler heads is narrow, and a sprinkler pipe system including the branch tee. The branch tee for sprinkler pipes includes a branch tee body (9) having a cylindrical shape, a first outlet (11) disposed on one end of the branch tee body (9) and connected to a pipe of a closed sprinkler head, an inlet (10) disposed on the branch tee body (9) and connected to a water supply pipe, a second outlet (12) disposed on the branch tee body (9) and connected to a pipe of an open sprinkler head, a piston valve disposed in the branch tee body (9) and simultaneously controlling opening and closing of each of the first outlet (11) and the second outlet (12) while moving in a longitudinal direction of the branch tee body (9) due to a fluid pressure difference in the branch tee body (9) when fire occurs, and an inner wall groove (18) defined in an inner wall of the branch tee body (9) between the piston valve and the first outlet (11). |
US10843017B2 |
Ultra high pressure water fire fighting system
A fire fighting vehicle includes a chassis, an engine coupled to the chassis, a fluid tank configured to store a fluid, a fluid delivery system, and a controller. The fluid delivery system includes a first pump, a second pump, a low pressure discharge, a first high pressure discharge, and a second high pressure discharge. The first pump is coupled to the fluid tank and configured to pump the fluid therefrom at a first pressure. The second pump is positioned downstream of and coupled to the first pump in a serial arrangement. The controller is configured to selectively vary at least one of a speed, a power output, and a torque output of the engine and thereby provide the fluid to at least one of the first high pressure discharge and the second high pressure discharge at a target discharge pressure. |
US10843011B2 |
Particle beam gun control systems and methods
Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 μsec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.4×10{circumflex over ( )}−6cGy/bunch. |
US10843009B2 |
Method, computer program product and computer system for radiotherapy treatment planning
A scenario-based radiotherapy treatment plan optimization method is used to define an extended region of interest for treatment planning purposes, based on the union of the positions of a region of interest in a number of different scenarios, each scenario representing a realization of a possible location of the region of interest. Preferably a number of scenarios are defined and some of these scenarios are used to define the extended region. |
US10843008B2 |
System and method for attaining target dose conformity in ion beam treatment
The present disclosure relates to a system, a method, a computer program and a computer readable medium for determining the thickness of a range shifter to attain target dose coverage in ion beam treatment, wherein the range shifter is for use in a machine for radiation treatment of a target volume, by: receiving, in a processor, input parameters comprising a radiation energy parameter, a range shifter material parameter, object geometry information, and beam characteristic parameters; and further calculating, for each of at least one delivery direction, a range shifter thickness, based on the input parameters, which will deliver the optimum dose conformity. |
US10843007B2 |
Determination apparatus for determining the pose and shape of an introduction element
A determination apparatus determines the pose and shape of an introduction element like a catheter within a living being, wherein the introduction element is adapted to be used by a brachytherapy apparatus for introducing a radiation source close to a target object to be treated. A position determination element like a guidewire with an electromagnetic tracking element is introduced into the introduction element such that it is arranged at different locations within the introduction element, wherein the positions of the position determination element within the introduction element are determined. The determined positions are then acquired depending on the determined positions for determining the pose and shape of the introduction element within the living being. This can lead to a determination procedure with reduced user interaction, thereby simplifying the determination procedure for the user. |
US10842996B2 |
Neural stimulation and recording, particularly for neuromodulation closed-loop control
A device for neurostimulation including an electrode structure for delivering stimulation pulses to a nerve as well as for processing and extracting evoked compound action potentials, wherein the electrode structure comprises at least a first anode, at least a second anode opposing the first anode and a plurality of cathodes arranged between said anodes, wherein said cathodes are asymmetrically arranged with respect to said at least first and second anode to permit evoked compound action potential sensing via the anode electrodes simultaneously with stimulation. |
US10842995B2 |
Method and system for use of hearing prosthesis for linguistic evaluation
A method and system to help determine the extent to which a hearing prosthesis recipient is exposed to speech. The hearing prosthesis will log data regarding audio input, optimally in correspondence with times when the hearing prosthesis is in a stimulation-on mode in which the hearing prosthesis is set to stimulate a physiological system of the recipient in accordance with received audio input, so as to facilitate identification of speech to which the recipient is exposed. Further, as the hearing prosthesis itself receives the audio input, the hearing prosthesis may analyze the audio input to determine one or more linguistic characteristics of the audio input, such as a quantity of speech by the recipient and/or by others, and the hearing prosthesis may output data representing the determined one or more linguistic characteristics. Advantageously, the data may then be used to help facilitate rehabilitation of the recipient. |
US10842991B2 |
Neural electrode system with a carrier having a tape spring-type shape
A neural probe comprising an array of stimulation and/or recording electrodes supported on a tape spring-type carrier is described. The neural probe comprising the tape spring-type carrier is used to insert flexible electrode arrays straight into tissue, or to insert them off-axis from the initial penetration of a guide tube. Importantly, the neural probe is not rigid, but has a degree of stiffness provided by the tape spring-type carrier that maintains a desired trajectory into body tissue, but will subsequently allow the probe to flex and move in unison with movement of the body tissue. |
US10842990B2 |
Flexible high-density mapping catheter tips and flexible ablation catheter tips with onboard high-density mapping electrodes
Flexible high-density mapping catheter tips and flexible ablation catheter tips with onboard high-density mapping electrodes are disclosed. These tips can be used for diagnosing and treating cardiac arrhythmias. The flexible, distal tips are adapted to conform to tissue and comprise a plurality of microelectrodes mounted to permit relative movement among at least some of the microelectrodes. The flexible tip portions may comprise a flexible framework forming a flexible array of microelectrodes (for example, a planar or cylindrical array) adapted to conform to tissue and constructed at least in part from nonconductive material in some embodiments. The flexible array of microelectrodes may be formed from a plurality of rows of longitudinally-aligned microelectrodes. The flexible array may further comprise, for example, a plurality of electrode-carrying arms or electrode-carrier bands. Multiple flexible frameworks may be present on a single device. A delivery adapter having an internal compression cone is also disclosed. |
US10842989B2 |
System to improve a spinal cord stimulation model based on a physiological midline location
Techniques for determining the location of a physiological midline and utilizing the physiological midline location to improve a spinal cord stimulation model are disclosed. A first improvement constructs a target stimulation field along a line that is parallel with the determined physiological midline. An allocation of stimulation among the electrodes to mimic the target field is computed. A second improvement models a response of neural elements at evaluation positions that are parallel with the physiological midline based on the electric field that is generated for the computed allocation of stimulation among the electrodes. The stimulation amplitude is adjusted based on the neural element modeling to maintain stimulation intensity, and the stimulation amplitude and allocation of stimulation among the electrodes are compiled into an electrode configuration that is communicated to a neurostimulator. |
US10842987B2 |
Tube clamp and volumetric pump comprising tube clamp
A medical tube clamp for clamping a flexible medical tube comprising: a tube receiving area which is adapted to receive the medical tube, a first clamping portion including a first clamping jaw which is movable relative to a second clamping portion including a second clamping jaw, and a closure system for safely positioning the two clamping portions in more than one snap-fit position relative to each other so that, when the closure system is unlocked, the medical tube can be inserted in and removed from the tube clamp, in an open snap-fit position the inserted medical tube cannot be removed and is not clamped and in a clamping snap-fit position the medical tube is clamped between the first clamping jaw and the second clamping jaw, with the first clamping jaw being configured to be elastically movable relative to the first clamping portion via a connecting member and/or the second clamping jaw being configured to be elastically movable relative to the second clamping portion via a connecting member. In addition, the invention relates to a volumetric pump. |
US10842986B1 |
Single-use cap
A single-use cap comprising a cap for connecting to an inlet or outlet of container, connector or port for accessing a material and a piston movably mounted inside the cap. The single-use cap further comprises a first retainer for temporarily holding the piston at a first unused position with respect to the cap. It also has a state converter for converting the piston from the first unused to a second used state when the single-use cap is used to connect to the outlet of the container, connector or port. Once the single-use cap is disconnected from the outlet of the container, connector or port, then a second retainer is activated for permanently retaining the piston in the second used state. The second used state prevents the single-use cap from being reused for connecting to the outlet of the container, connector or port. The second used state causes the piston to block a means for connecting the single-use cap to such an inlet or outlet of container, connector or port, in some instances, such as threads that mate with the container, connector or port. |
US10842974B2 |
Systems and methods for selectively occluding the superior vena cava for treating heart conditions
Systems and methods and devices are provided for treating conditions such as heart failure and/or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure. |
US10842973B2 |
Mechanically assisted inflation device handle and method of use
An inflation device including a handle mechanism configured to selectively engage and disengage threads within the device. In some instances the threads are configured to couple a plunger to a syringe body. The handle mechanism may be configured to (1) provide a mechanical advantage and (2) change the location and direction of the input force, thereby making the device easier to use. |
US10842970B2 |
Surgical access system
A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either device within the brain. |
US10842969B2 |
Systems and methods of treating malacia by local delivery of hydrogel to augment tissue
Systems, devices, and methods for maintaining patency in a bronchus of a patient are presented. A catheter is positioned within the bronchus. A target region of one or more of a bronchial wall, submucosa, media, and adventitia is punctured with an injection needle disposed on a distal end of the catheter. Such puncturing is achieved by expanding a balloon disposed on the distal end of the catheter. The balloon may be comprised of at least two materials of different elastic modulus, which allows for a flexible but relatively non-distensible, unfolding component of the balloon as well as an elastomeric, inflatable component of the balloon. Through the injection needle, an amount of one or more crosslinking agents is delivered to the target region. The delivered amount is effective to provide structural support for the bronchial wall, substituting for the bronchial cartilage thereby treating bronchomalacia. |
US10842963B2 |
Intubation stylet with video feed
A manually articulated stylet assembly for placing an endotracheal tube. The stylet assembly has a steering shaft that carries a flexible distal tip at one end and is attached to a handle at the other end. The distal tip is manipulated via sheathed cables controlled by a remote actuator in the handle. A biasing member inside the remote actuator maintains continuous tension on the cables to improve control. A video camera is carried in a recessed lens pocket in the steering shaft but spaced from the distal tip. The camera FOV captures movement of the distal tip with foreshortened perspective. A collar seat in the handle receives the collar connector of a standard endotracheal tube, providing quick disconnect when removing the stylet assembly upon placement. |
US10842960B2 |
Breathing gas delivery system
A breathing gas delivery system comprising a gas flow controller, at least one breathing apparatus, and at least one first length of tubing coupling the breathing apparatus to the gas flow controller. The gas flow controller has a body having an on/off switch, at least one gas input, at least one gas output, and at least one control mechanism for controlling flow of gas to the gas output. The breathing apparatus comprises a T-shaped gas input, a breathing bag coupled to the T-shaped gas input, a second length of tubing having two opposed ends, wherein one end is coupled to the other arm of the T-shaped gas input, a filter coupled the second length of tubing, and a nasal assembly coupled to the filter. |
US10842959B2 |
Foot pedal
The invention relates to an ergonomic foot pedal and to apparatuses for manual ventilation. In an embodiment, the invention provides a compact and integrated foot pedal that enables a care provider to provide positive pressure ventilation to a subject's airways and lungs, and to optionally apply suction for the purpose of aspirating mucous, secretions, meconium, blood, fluids or other such materials from a patient—specifically from airways. |
US10842958B1 |
Method and system for diagnosis and treatment of sleep disordered breathing of a patient
A system and method for providing ventilatory support to a patient suffering from sleep disordered breathing (SDB), in particular, non-obstructive SDB, such as Cheyne Stokes respiration and hypoventilation, including obesity hypoventilation syndrome. The system and method monitor obtain data corresponding to a breathing pattern of a patient and determine when the patient experiences oscillating breathing or low spontaneous ventilation. In particular, the system and method determine when the patient's real-time breathing patterns fall below a predetermined baseline threshold, and subsequently initiate a short series of mechanical breaths to be delivered to the patient. |
US10842956B2 |
Respiratory breathing apparatus
A respiratory apparatus comprising a base and removable chamber, wherein the chamber is configured to hold a supply of water and include a blower arrangement adapted to provide a supply of pressurized air or gas to the supply of water. In certain embodiments the respiratory apparatus includes a split motor, wherein the stationary components are located within a base and the rotating portions are located within a chamber. |
US10842954B2 |
Aerosol-generating system having a cartridge with a side aperture
An aerosol-generating system includes a cartridge and an aerosol-generating device configured to receive the cartridge. The cartridge includes a cartridge housing and a cartridge aerosol-forming substrate within the cartridge housing. The cartridge housing has a first end, a second end, a first side between the first end and the second end, and at least one aperture on the first side. The aerosol-generating device includes a device housing, a liquid aerosol-forming substrate, an electric heater, a power supply, and a controller. The device housing defines a cavity, a cavity air inlet, and a cavity air outlet. The cavity is configured to receive the cartridge such that an airflow from the cavity air inlet to the cavity outlet flows through the cartridge via the at least one aperture during an operation of the aerosol-generating system. |
US10842948B2 |
Retractable syringe
An auto-retractable syringe having a barrel and a plunger wherein engagement of said plunger with an otherwise immobilised needle hub allows a biasing member to push the needle hub into a cavity in the plunger. |
US10842943B2 |
Drug dispensing-tracking device, system and method
Embodiments of the present disclosure present systems, methods and devices related to the tracking of drugs injected by injection devices. For example, in some embodiments, a drug dispensing-tracking device for use in combination with a drug-injection device is provided, where the device comprises a sleeve configured to connect with at least one mechanical feature provided on the injection device, a battery, at least one sensor, an electrical circuit for analog or digital short range communication, and a transmission element. In some embodiments, for each injection, the sensor is configured to automatically detect at least one of an auditory signal, movement, and optical signal, and an auditory signal is generated by at least one of the setting of the injection device for dispensing a drug, the dispensing action of the injection device, and the flow of the drug out of the injection device. |
US10842940B1 |
Adhesive thumb ring and syringe assembly, and an adhesive thumb ring for a syringe
An adhesive thumb ring for a syringe is provided including a ring body and an adhesive surface on the ring body. The adhesive surface is configured to adhere to a plunger head on a syringe barrel of a syringe. For instance, the adhesive thumb ring can be rapidly and securely attached to a curved, T-shaped plunger head of a typically pre-filled, pre-packaged dermal filler syringe. The adhesive thumb ring is particularly suitable for facilitating one-handed pushing and pulling operation of the syringe in the injection of dermal filler into the skin of a patient, significantly assisting the syringe operator in preventing vascular occlusion. |
US10842935B2 |
Systems and methods for determining insulin therapy for a patient
In example methods and systems described, insulin therapy for a patient can be determined. At least one of a short-acting subcutaneous insulin dosage recommendation, a correction subcutaneous insulin dosage recommendation, an intravenous insulin dosage recommendation, a recommended amount of carbohydrates to be administered to the patient, or combinations thereof, can be determined. In addition, information indicating a confirmation of a nutrition intake for the patient, and a long-acting insulin-on-board for the patient can be received, and based on this information, a required long-acting subcutaneous or intravenous insulin dosage for the patient can be determined. The short-acting subcutaneous or intravenous insulin dosage recommendation can be adjusted based, at least in part, on a difference between the long-acting insulin-on-board and the required long-acting subcutaneous or intravenous insulin dosage. |
US10842933B2 |
Reservoir for collection and reuse of diverted medium
A system allows for collection and re-use of a fluid medium derived from diverting at least some of the fluid medium of an injection. The system comprises a sterile container, an injector, a delivery catheter, a flow diverter assembly and a diversion reservoir assembly. The delivery catheter is in communication with a selected site within a patient's body. The flow diverter assembly is disposed in a flow path between the injector and the delivery catheter and is configured to divert at least a portion of a medium of the injection from the flow path. The diversion reservoir assembly has a reservoir chamber fluidly coupled to the flow diverter assembly. The reservoir chamber is configured to receive the diverted portion of the fluid medium to allow re-use by the medium injector of the diverted portion. |
US10842932B1 |
Intelligent pharmaceutical delivery system with non-concentric pumping mechanism to reduce flow anomaly and method of using
The present invention relates to the titration and delivery of anesthetic and sedative medications to a subject. Further, the present invention relates to a device and methods for titrating and delivering such medications in a semi-automated or fully automated manner and which can be monitoring and controlled remotely. Even still further, the present invention relates to such a device that can perform the titration and delivery of medication in a manner that minimalizes occlusion and prevents back flow of the medication. More particularly, the present invention relates to a device for titration and delivery of medication using a non-concentric pumping mechanism that gradual or progressively increases and decreases occlusion in the medication delivery line within the pump to minimize and/or prevent sudden formation and release of occlusion in order to provide more steady and continuous flow of the medication through the device to the subject. |
US10842926B2 |
Medical fluid treatment machines and related systems and methods
A method comprising: receiving patient assessment information concerning one or more subjective characteristics of a patient; determining a patient assessment score based on the received patient assessment information; and modifying operation of a medical fluid treatment machine based on the patient assessment score. |
US10842916B2 |
Injectable porous device for treatment of dry and wet age-related macular degeneration or diabetic retinopathy
This disclosure provides a method for reducing or preventing the formation and/or accumulation of drusen in an eye of a mammalian subject in need thereof, the method comprising implanting one or more microporous devices into the eye, each device having a device body and an outer surface, wherein the microporous device is formed of a biocompatible elastomeric material and comprises a plurality of interconnected pores throughout the device body. |
US10842913B2 |
Scalable three-dimensional elastic construct manufacturing
Tissue repair and restoration can be performed using an elastic material formed from tropoelastin. The elastic material can be formed by providing a solution of tropoelastin monomers, applying the solution to a surface, and heating the solution on the surface in absence of a cross-linking agent to enable the tropoelastin monomers to bind to each other to form an elastic material that does not dissociate into tropoelastin monomers when the elastic material is contacted with an aqueous solution. |
US10842912B2 |
Functionalized PEG for implantable medical devices
A coating for a metal surface, the coating including poly(ethylene glycol) disposed on and covalently bonded directly to at least a portion of the metal surface, and a functional group grafted to at least a portion of the poly(ethylene glycol). The functional group is one of a bioactive functional group and an antimicrobial functional group. |
US10842910B2 |
Systems for drying sheets of donor-provided human tissue
Embodiments of this technology may include an apparatus for drying tissue. The apparatus may include human donor tissue placed in contact with and between at least two layers of backing material. This tissue and backing layer may then be restrained by two plates. This tissue may be amniotic tissue. The backing layer may include woven or nonwoven material. This backing layer may be wetted with a saline solution. At least one of the plates of the tissue drying apparatus may be perforated. The tissue assembly along with the plates may then be placed inside a chamber configured to receive the plates and tissue assembly. The chamber may be configured so that gas can be forced into the chamber with the gas flow going around the plates and the tissue assembly. |
US10842907B2 |
Fluid disinfection device and method
A system for disinfecting a fluid containing contaminants (chemical and biological) includes a plurality of photocatalytic particles secured to a substrate which contacts the fluid to be disinfected. An agitator for imparting translation and/or vibrational movement is in operational communication with the substrate to increase the contact of photocatalytic particles with contaminants in the fluid. The system can include a source of photons having a wavelength corresponding to band gap energy of the photocatalytic particles to illuminate the substrate. Although the invention can be used to disinfect air in air supply registers of a heating, ventilating and air conditioning system, or in air ducts, the disinfection of any fluid (including water) is contemplated. |
US10842905B2 |
Air sterilizer
Provided is an air sterilizer for filtering and discharging harmful components from inflowing air, comprising: a body having an air inlet part, through which outside air is introduced, and an air outlet part, through which the air filtered inside is discharged; a primary filtering part detachably provided in the body and filtering contaminant particles from the inflowing and moving air; an air intake fan for allowing the air to inflow through the air inlet part; a secondary electrostatic filter part for sterilizing harmful components from the air, which has been filtered through the primary filtering part, by applying continuous and repetitive damage to the harmful components; and an ion-generating part for supplying anions to the air, from which the harmful components have been filtered through the secondary electrostatic filter part, so as to allow the air to be discharged to the outside. |
US10842902B2 |
Treated membrane for fragrance delivery
A treated vapor permeable microporous membrane includes: a microporous membrane having a first side and a second side opposite the first side. The membrane includes a thermoplastic organic polymer having a polyolefin. The membrane defines a network of interconnecting pores communicating substantially throughout the membrane. The treated membrane further includes finely divided, particulate filler distributed throughout the membrane and a first hydrophobic/oleophobic material over at least a portion of the first side. A method of preparing the treated vapor permeable microporous membrane is also disclosed. |
US10842901B2 |
Plug-in fragrance dispenser
A plug-in fragrance dispenser contains: a body, an electric plug, a heating element, a heat transfer plate, and a holder. The electric plug is electrically connected with a power source, and the body is coupled with the electric plug and includes a first orifice, a first connection part, and a second connection part. The first connection part is connected with the second connection part, the first connection part has an accommodation lid and a surround sleeve, and the surround sleeve has the first orifice defined on a top thereof. The accommodation lid has a second orifice in which the electric plug is accommodated, the second connection part has a support seat and a first cap formed on an upper end of the support seat and connecting with a bottom of the surround sleeve, wherein the support seat is housed in the accommodation lid. |
US10842900B2 |
Air treatment article
An air treatment article is provided, comprising: a semipermeable barrier and a plurality of multi-staged non-film forming polymer abatement particles having a core polymer and at least one shell polymer; wherein the core polymer accounts for 1 to 25 wt % of the weight of the non-film forming polymer abatement particles; wherein the semipermeable barrier is disposed between an air atmosphere and the non-film forming polymer abatement particles; wherein the semipermeable barrier impedes passage therethrough by the non-film forming polymer abatement particles; wherein the semipermeable barrier permits passage therethrough by a for-treatment air containing a contaminant such that the for-treatment air can make contact with the non-film forming polymer abatement particles; wherein the non-film forming polymer abatement particles have an affinity for the contaminant. |
US10842899B1 |
Non-contact sanitizer dispenser glove
A sanitizer dispensing glove and a method of sanitizing an object using the glove. The sanitizer dispensing glove has a spray mechanism which is located on the palmar surface of a glove or mitt which is able to be operated to spray a sanitizer solution onto an object by a flexing or closing of a hand, finger, or other appendage wearing the glove without making contact with the object. |
US10842898B2 |
Devices, systems and methods for treating medical devices having passageways with ozone gas
The present disclosure is generally related to devices, methods and systems for cleaning, disinfecting and/or sterilizing a medical device, medical hoses and tubes and accessories thereof with ozone gas, in particular the disclosure relates to devices, methods and systems with multiple receptacles for providing closed-loop fluid pathways to distribute ozone gas to inner passageways and the outer compartments of medical devices. The devices in accordance with an embodiment of the disclosure have two or more receptacles for distributing ozone gas, a gas-tight compartment, an ozone operating system, and one or more connector units configured to fluidly migrate ozone in closed-loop treatment systems. |
US10842897B2 |
Disinfecting articles with ozone
The present invention extends to methods, apparatus, and systems for disinfecting articles with ozone. Aspects of the invention use increased concentrations ozone in sealed, confined volumes, such as, for example, carts, lockers, cabinets, etc. to disinfect or sterilize medical articles. A medical article is placed in a confined volume. The confined volume is sealed so that the atmosphere inside the sealed, confined volume is isolated from the external atmosphere. The concentration of ozone in the sealed, confined volume is rapidly increased to a threshold concentration. At the threshold ozone concentration, the medical article can be disinfection or sterilized in a reduce amount of time. When disinfection or sterilization is complete, the concentration of ozone in the sealed, confined volume is rapidly reduced to a safe level. The sealed, confined volume is unsealed. The disinfected or sterilized medical article can be removed from the confined volume. |
US10842892B2 |
Methods and apparatus for synthesizing imaging agents, and intermediates thereof
The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located. |
US10842891B2 |
Imaging histone deacetylases with a radiotracer using positron emission tomography
Disclosed herein are histone deacetylase imaging agents for positron emission tomography and related imaging methods using the histone deacetylase imaging agents. The histone deacetylase imaging agents may be a compound of formula (I): wherein R1 is a moiety including a positron emitter; R2 represents hydrogen, or substituted or unsubstituted alkyl, or substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and n is an integer selected from 0 or 1. In one version of the compound of formula (I), R1 is a moiety including an adamantyl group. |
US10842890B2 |
Contrast agent and associated methods
Example substances and methods relating to contrast agents are provided. An example method includes combining a surface active protein, a stabilizer, and a dispersion media to form a solution. The example method may further include aerating the solution in a gas to form a contrast agent comprising at least one microbubble formed from an interaction between the surface active protein and the stabilizer. A diameter of the at least one microbubble may be proportional to a pressure of an external environment of the contrast agent, such that measurement of the diameter may allow for measurement of the pressure. |
US10842888B2 |
Plastic containers
The present invention provides a method for the commercial presentation of a solution of gadolinium-DOTA that provides certain advantages over the known methods. |
US10842887B2 |
PSMA-targeted NIR dyes and their uses
The present disclosure relates to prostate specific membrane antigen (PSMA) targeted compounds conjugated to near-infra red (NIR) dyes and methods for their therapeutic and diagnostic use. More specifically, this disclosure provides compounds and methods for diagnosing and treating diseases associated with cells and/or vasculature expressing prostate specific membrane antigen (PSMA), such as prostate cancer and related diseases. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds. |
US10842884B2 |
Endosomolytic agents for gene therapy
Compounds of formula (I), wherein Ar is an aryl group optionally further substituted with one or more groups R3; A is a lipophilic, hydrophobic moiety; R1 is a phosphodiester, phosphotriester, thioether or amide group; X is an unsubstituted or substituted C6 to C24 alkylene or alkenylene group, which is optionally interrupted by one or more —NR9—, —O— or —S— linkages, R2 is —YC(R4)(R5)CO2R6; and pharmaceutically acceptable salts or solvates thereof are useful as endosomolytic agents particularly for the delivery of nucleic acids useful in gene therapy. |
US10842882B2 |
Amatoxin-antibody conjugates
The invention relates to conjugates comprising amatoxins and antibodies, in particular amatoxins linked to antibodies comprising specific cysteine residues. |
US10842880B2 |
Immobilised biological entities
There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an anti-coagulant entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which anti-coagulant entity is covalently attached to said surface through a linker comprising a thioether. |
US10842879B2 |
Long-acting adrenomedullin derivative
The invention provides a novel adrenomedullin derivative sustainable for a long period which is capable of substantially suppressing unwanted side effects while maintaining pharmacological effects of adrenomedullin. In an exemplary embodiment, the invention relates to a compound represented by formula (I): A-CH2—B (I) [wherein A is a modifying group comprising one or more polyethylene glycol groups, and B is a peptide moiety derived from adrenomedullin or a modified form thereof with adrenomedullin activity, wherein the peptide moiety B is linked to the other moieties through a covalent bond of the nitrogen atom of the N-terminal α-amino group of the peptide moiety B to the carbon atom of the methylene group] or a salt thereof, or a hydrate thereof. |
US10842878B2 |
Degradation of Bruton's tyrosine kinase (BTK) by conjugation of BTK inhibitors with E3 ligase ligand and methods of use
The present application provides bifunctional compounds of Formula (I): or an enantiomer, diastereomer, or stereoisomer thereof, or pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, which act as protein degradation inducing moieties for Bruton's tyrosine kinase (BTK). The present application also relates to methods for the targeted degradation of BTK through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to BTK which can be utilized in the treatment of disorders modulated by BTK. |
US10842874B2 |
Sensitization of bacterial cells to quinolone antibiotics
Provided herein are pharmaceutical compositions and kits useful for sensitizing a microorganism or a population of microorganisms to a quinolone antibiotic. In a particular aspect, a carbon source and an electron acceptor can sensitize an antibiotic persistent microorganism to treatment with a fluoroquinolone antibiotic. Methods for sensitizing a microorganism to a quinolone antibiotic, reducing the density-dependent persistence (DDP) of an antibiotic resistant microorganism, and reducing the number of persistent cells in a population are also provided. Theses compositions and methods are useful in treating infections resulting from high-density bacterial cultures, such as pneumonia, genitourinary infections, biofilms, prosthetic graft infections, sepsis, and endovascular infections. |
US10842871B2 |
Methods for treating Alzheimer's disease
A method for treatment of a human patient for Alzheimer's disease (AD) comprises sequentially administering multiple doses of a recombinant, fully human, anti-amyloid beta monoclonal antibody to the patient. In preferred embodiments, the antibody is administered in increasing amounts over a period of time. In preferred embodiments, the susceptibility of the patient to amyloid related imaging abnormalities (ARIA) is thereby reduced. |
US10842869B2 |
Method of treating lupus by administering humanized anti-CXCR5 (C-X-C motif chemokine receptor 5) antibodies
This disclosure provides anti-CXCR5 antibodies and their use in the amelioration, treatment, or prevention of lupus. The disclosure also provides prophylactic, immunotherapeutic, and diagnostic compositions comprising an anti-CXCR5 antibody, and the use of such anti-CXCR5 antibodies in methods of preventing or treating lupus in mammals, including humans. |
US10842868B2 |
Adjuvanted formulations of booster vaccines
The invention improves TdaP vaccines by including a TLR agonist in them. This agonist can provide stronger protection, longer-lasting protection, and/or can reduce the amount of antigen which is required to achieve a particular immune response. |
US10842864B2 |
MVA vaccine for delivery of a UL128 complex and preventing CMV infection
In one embodiment, an expression system for expressing a UL128 complex is provided herein. The expression system may include a bacterial artificial chromosome (BAC) construct, wherein the BAC construct comprises a viral vector inserted with a set of DNA sequences that encode a UL128 complex. In another embodiment, a vaccine composition for preventing HCMV infection is provided. The vaccine composition may include a viral or bacterial vector capable of expressing a UL128 complex and a pharmaceutically acceptable carrier, adjuvant, additive or combination thereof or additional vector expressing a protein adjuvant. The viral vector may be an MVA and the UL128 complex includes five HCMV proteins or antigenic fragments thereof: UL128, UL130, UL131A, gL, and gH. In some embodiments, the viral vector is further inserted with one or more additional DNA sequences that encode one or more additional HCMVHCMV proteins or antigenic fragments thereof such as pp65, gB or both, or such as gM/gN or gO. |
US10842858B2 |
Compositions and methods of enhancing immune responses to Eimeria
Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites. |
US10842853B2 |
Viral vectors encoding recombinant fix with increased expression for gene therapy of hemophilia B
Codon-altered polynucleotides encoding Factor IX variants for expression in mammalian cells are provided, including sequences with high nucleotide sequence identity to the CS02, CS03, CS04, CS05, and CS06 sequences. Mammalian gene therapy vectors, such as adeno-associated viral vectors, and methods for treating hemophilia B using those vectors are also provided. |
US10842852B2 |
Methods of delivering a polypeptide molecule to Otx2 target cells using an Otx2 targeting peptide
The disclosure provides a method of delivering a polypeptide molecule to an Otx2 target cell, including contacting the target cell with a chimeric polypeptide having (i) a targeting peptide consisting of SEQ ID NO: 2 and (ii) the polypeptide molecule. |
US10842849B2 |
Methods for promoting neuronal outgrowth by insulin-like growth factor binding protein-like 1 (IGFBPL-1) in glaucoma or leber's optic neuropathy
Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
US10842848B2 |
Method for treating cancer by adminstering poly I:C and LAG-3-IgG fusion protein
The present invention provides a medicine containing a Toll-like receptor agonist, LAG-3 protein, a variant or derivative thereof. |
US10842844B2 |
Phosphorylcholine conjugates and uses thereof
The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation. |
US10842843B2 |
Augmenting the immune response by promoting cell death of immune cells
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject. |
US10842830B2 |
Methods and compositions relating to microbial treatment and diagnosis of disorders
The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions. |
US10842829B2 |
Natural product to improve immunity and combat viral diseases, bacterial diseases, fungal diseases, and cancer diseases
A natural product for improving health and reducing the risk of death due to dangerous diseases comprises a presence of figs and Acetobacter pasteurianus. |
US10842828B2 |
Methods of treating cancer using bacteria expressing c-di-AMP
Described herein are methods of treating or preventing cancer in a subject comprising administering to the subject an effective amount of a bacteria comprising and expression vector encoding a di-adenylate cyclase enzyme. |
US10842827B2 |
Treatment and compound for epithelial wounds
There are disclosed an effective dosage of major royal jelly protein 1 for treating various skin ailments. Instead of administering royal jelly, an effective amount of the active constituent of royal jelly, MRJP1 is administered either alone or in combination with other topical pharmaceuticals. |
US10842826B2 |
Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
The disclosure provided herein relates generally to mesenchymal-like stem cells “hES-T-MiSC” or “T-MSC” and the method of producing the stem cells. The method comprises culturing embryonic stem cells under conditions that the embryonic stem cells develop through an intermediate differentiation of trophoblasts, and culturing the differentiated trophoblast in hES-T-MSC or T-MSC, T-MSC derived cells and cell lineages “T-MSC-DL” are also described. Disclosed also herein are solutions and pharmaceutical compositions comprising the T-MSC and/or T-MSC-DL, methods of making the T-MSC and T-MSC-DL, and methods of using the T-MSC and T-MSC-DL for treatment and prevention of diseases, specifically. T-MSC and T-MSC-DL are used as immunosuppressive agents to treat multiple sclerosis and autoimmune diseases. |
US10842825B2 |
Liquid amnion transplant product
A transplant product made from human amniotic fluid has a supernatant from filtered and centrifuged amniotic fluid, the amniotic fluid when recovered aseptically having a clear, translucent to slightly pink or tan color. The supernatant had been taken from the amniotic fluid which had been passed through a 170 to 260 micron blood filter, then centrifuged for 5 minutes or more at 400 g and thereafter the supernatant was separated from a pellet of debris, leaving the biochemical properties intact, wherein the supernatant is cryofrozen in sized cryovials having 0.25 to 2.0 ml of the supernatant at a temperature of −65 degrees or less prior to use and the transplant products method of use. The transplant product contains cellular material, cell fragments, proteins and growth factors maintaining the biochemical properties and is non-immunogenic while having particles up to 170 microns being passable through a 30 gauge syringe for injection. |
US10842821B2 |
Cellular compositions derived from prior organ donors and methods of manufacture and use thereof
The invention provides methods of making and using compositions for establishing mixed chimerism in a subject that include CD34+ cells and CD3+ cells derived from an apheresis product obtained from a subject that has previously donated a solid organ. |
US10842820B2 |
Kits and methods for processing stem cells from bone marrow or umbilical cord blood
Provided herein are kits for processing stem cells from bone marrow or umbilical cord blood, comprising: a) a precipitation reagent comprising an aqueous solution of 0.1-30% hydroxyethyl starch or 0.1-30% methyl cellulose, and 0.1-20% of cerebroprotein hydrolysate; and b) a separation reagent comprising an aqueous solution comprising Ficoll and diatrizoate and having a density of 1.0-1.2 g/ml, and methods of use. Further provided herein is a collection of stem cells obtained by the kits and methods disclosed herein comprising stem cells from bone marrow or umbilical cord blood, and uses thereof. |
US10842815B2 |
Perispinal perfusion by administration of T regulatory cells alone or in combination with angiogenic cell therapies
Disclosed are method of enhancing perispinal perfusion in a patient suffering from reduced perfusion of the lower back through administration of T regulatory cells alone capable of stimulating angiogenesis directly or through enhancement of angiogenic activities of cellular therapies. Said cellular therapies possessing angiogenic activities include mesenchymal stem cells, hematopoietic stem cells and endothelial progenitor cells. In one embodiment of the invention, administration of T regulatory cells is performed that are expanded ex vivo. For certain embodiment of the invention T regulatory cells may be autologous or allogeneic. |
US10842812B2 |
Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders
Methods of promoting hypoxia or the hypoxia response for the treatment or prevention of mitochondrial dysfunction and oxidative stress disorders are described. Methods for screening for targets of mitochondrial dysfunction and oxidative stress disorders are also described. |
US10842811B2 |
Inulin for preventing antibiotic resistant infection and pathogen colonization
The present disclosure provides for methods and compositions for the treatment and prevention of antibiotic-resistant infections or pathogen colonization in critically ill patients in the intensive care unit (ICU) or in other populations at high risk for such infections. |
US10842810B2 |
Continuous release compositions made from hyaluronic acid, and therapeutic applications of same
The present invention concerns polymer particles made from poly(lactic-co-glycolic acid) (PLGA) polymer, poly(lactic-co-glycolic acid)-polyethylene glycol-poly(lactic-co-glycolic acid) (PLGA-PEG-PLGA) copolymer, or the mixture of same, combined with hyaluronic acid molecules or hyaluronic acid salts, and the method for preparing same. The present invention also concerns injectable pharmaceutical or cosmetic compositions comprising such polymer particles, the method for preparing such compositions, and the use thereof for medical purposes, in particular for the prevention and/or treatment of musculoskeletal diseases, diseases and traumatic conditions of the skin, oral disorders, vaginal mucosa dryness and urinary infections or cystitis, dryness of the eye membrane and eye infections, obesity, and the use of same to combat ageing of the skin and/or for repairing the dermal tissue (mesotherapy). |
US10842808B2 |
Polypeptide having the capacity to form alpha-1,3 glucosyl unit branchings on an acceptor
Polypeptides having the ability to specifically form connections of glucosyl units in alpha 1,3 on an acceptor having at least one hydroxyl moiety are presented. The polypeptides include i) the pattern I of sequence SEQ ID NO: 1, ii) the pattern II of sequence SEQ ID NO: 2, iii) the pattern III of sequence SEQ ID NO: 3, and iv) the pattern IV of sequence SEQ ID NO: 4, or derivates from one or several of said patterns, wherein the polypeptide furthermore has an aspartic residue (D) at position 5 of the pattern II (SEQ ID NO: 2), a glutamic acid residue (E) at position 6 of the pattern III (SEQ ID NO: 3) and an aspartic acid residue (D) at position 6 of the pattern IV (SEQ ID NO: 4). Methods for producing acceptors connected to glucosyl units in alpha 1,3 using the polypeptides are also provided. |
US10842807B2 |
Methods of treating neurodegenerative disorders comprising DNA methyltransferase inhibitors
The present disclosure provides a method of treating a neurodegenerative disorder, the method comprising administering a DNA methyltransferase inhibitor. |
US10842805B2 |
Compositions containing enriched natural crocin and/or crocetin, and their therapeutic or nutraceutical uses
The invention relates to unique compositions containing enriched and purified natural crocin and/or crocetin for prevention and/or treatment of cancers and other conditions and diseases. Compositions comprise mainly enriched or purified natural crocin or crocetin or combination of both and possible other active phytochemicals. A composition is used as functional food, drink, dietary supplement, or therapeutic dosage to a human orally or through other appropriate way (parenteral, percutaneous, rectal, mucosal, intranasal or topical administration). A method of natural crocin and crocetin enriching and purification is revealed. |
US10842803B2 |
Imidazopyridines Syk inhibitors
Certain imidazopyridines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample. |
US10842801B2 |
Optimizing mifepristone absorption
The present invention provides a method for altering the pharmacokinetics of mifepristone upon oral administration. Mifepristone absorption into the blood is increased upon administration with meals. The method of the invention can benefit patients suffering from conditions including psychiatric illnesses and hormonal disorders. |
US10842795B1 |
Chemosensitization of resistant Pseudomonas aeruginosa by synthetically related compounds
Compounds for the chemosensitization of antibiotic resistant bacteria such as multidrug resistant (MDR) Pseudomonas aeruginosa (Pa) are provided. The compounds inhibit the MDR efflux proteins and re-sensitize the bacteria towards killing by antibiotics. Thus, the compounds are used in combination with antibiotics to treat or prevent infections caused by MDR bacteria. |
US10842792B2 |
Deuterated baricitinib
The present invention in one embodiment provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula I are as defined in the specification, as well as pharmaceutical compositions comprising the same, and methods of using such compounds and compositions to inhibit at least one of Janus Kinase-1 and -2 and diseases associated with those kinases. |
US10842791B2 |
Small molecule inhibitors of EGFR and PI3K
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases. |
US10842788B2 |
Application of levorotatory tetrahydropalmatine to the treatment of depression disorders, bipolar and related disorders, and manic episodes
The compound levorotatory-tetrahydropalmatine and pharmaceutical compositions thereof are provided for the treatment of ‘depressant disorders’, ‘bipolar and related disorders’, ‘manic episodes’ and ‘anxiety disorders’ as these disorders are defined in Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5). |
US10842780B2 |
Pharmaceutical composition for modified release
A pharmaceutical composition for modified release, comprising (1) (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide, or a pharmaceutically acceptable salt thereof, (2) at least one additive which ensures penetration of water into the pharmaceutical composition and which has a solubility such that the volume of water required for dissolving 1 g of the additive is 10 mL or less, and (3) a hydrogel-forming polymer having an average molecular weight of approximately 100,000 or more, or a viscosity of 12 mPa·s or more at a 5% aqueous solution at 25° C. is disclosed. |
US10842771B2 |
Composition of docetaxel liposomal injection with high drug loading
The present invention relates to a pharmaceutical liposomal composition comprising of about 0.8% w/w to about 1% w/w of docetaxel, about 30% w/w to about 38% w/w of Soya Phosphatidyl Choline, about 0.2% w/w to about 0.8% w/w of Sodium Cholesteryl Sulfate, about 61% w/w to about 68% w/w of Sucrose and a pH adjusting agent, wherein the pH of liposomal composition is less than 3.5 and the process for preparation thereof. |
US10842769B2 |
Organoarsenic compounds and methods for the treatment of cancer
A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3′, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol. |
US10842768B2 |
Compositions and methods for lowering triglycerides
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof. |
US10842767B2 |
Use of ketone esters for prevention of CNS oxygen toxicity
The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and Aβ-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two. |
US10842765B2 |
Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing sdLDL oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. |
US10842763B2 |
Methods for cancer and immunotherapy using prodrugs of glutamine analogs
The disclosure provides methods of treating cancer in a subject or preventing a relapse or reducing the incidence of relapse of cancer in a subject in remission, comprising administering to the subject: (a) a therapeutically effective amount of an immunotherapeutic agent, e.g., an immune checkpoint blockade therapy, an adoptive cellular therapy, a marrow-infiltrating lymphocytes, an adenosine A2aR inhibitor, or an antibody; and (b) a compound having formula (I): and the pharmaceutically acceptable salts thereof, wherein R1, R2, R2′, and X are as defined as set forth in the specification. Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON). |
US10842762B2 |
Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent
Methods of treating and/or preventing a cardiovascular event in a patient, the method comprising orally administering a colchicine to a patient who is receiving concurrent treatment with at least one antiplatelet agent, thereby treating and/or preventing the cardiovascular event in the patient are provided. |
US10842761B2 |
Treatment or prevention of cardiovascular events via the administration of a colchicine derivative
A method for the treatment or prevention of a cardiovascular event in a subject with atherosclerotic vascular disease comprising the step of: b) administering a therapeutically effective amount of a compound of formula (I), a known colchicine derivative and/or a salt thereof wherein: R1, R2, R3, R4, R9, R10, R11 and R12 independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-6 cycloalkyl, halogen, C1-4 haloalkyl, nitro, amino, C2-4 acylamino, C1-4 alkyl or dialkylamino, hydroxyl, C1-4 alkoxy, C1-4 alkylthio, a group of the formula —SO2N(Rx)2 or SO2Rx where Rx is C1-4 alkyl, C1-4 acyloxy, or optionally substituted phenyl, optionally substituted phenoxy; R7 and R8 independently represent hydrogen, C1-4 alkyl or C1-4 acyl; and R5′, R5″, R6′ and R6″ independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-6 cycloalkyl, halogen, C1-4 haloalkyl, nitro, amino, C2-4 acylamino, hydroxyl, C1-4 alkoxy or C1-4 alkylthio a group of the formula —SO2N(Rx)2 or SO2Rx where Rx is C1-4 alkyl, C1-4 acyloxy, or optionally substituted phenyl. |
US10842758B1 |
Transdermal penetrant formulations containing cannabidiol
Disclosed herein is a transdermal delivery formulation for transdermal delivery of a Cannabidiol, with or without one or more additional active agents through the dermis, including the skin, nail or hair follicle of a subject, wherein the formulation comprises a) a transdermal delivery formulation in an amount less than about 60% w/w, comprising i. one or more phosphatides, ii. glucose, and iii. one or more fatty acids; b) water in an amount less than about 50% w/w, a Cannabidiol with or within one or more additional active agents. |
US10842755B2 |
Nanoparticles for brain targeted drug delivery
A nanoparticle suitable for delivery of an active agent across the blood-brain barrier is provided. As such, the nanoparticle can target brain tissue so that the active agent can be delivered across the blood-brain barrier to the target brain tissue. The nanoparticle includes a core that includes a core material such as a polymer or inorganic material as well as an active agent; and a shell comprising a membrane derived from a brain metastatic cancer cell, wherein the brain metastatic cancer cell facilitates transport of the nanoparticle across a blood-brain barrier. Also disclosed are methods of forming the nanoparticle and methods of using the nanoparticle. |
US10842754B2 |
Deoxyribonucleic acid nanoparticles for delivering proteins and protein-containing compounds and methods of manufacturing deoxyribonucleic acid nanoparticles
Non-viral delivery platforms are provided for facilitating transport of molecules across cell membranes. In some forms, DNA nanoshells capable of transporting cargo molecules are formed, and may be formed in order to surround a variety of materials for a variety of purposes. |
US10842751B2 |
Pharmaceutical compositions containing doravirine, tenofovir disoproxil fumarate and lamivudine
The instant invention relates to pharmaceutical compositions comprising doravirine, tenofovir disoproxil fumarate and lamivudine. These compositions are useful for the treatment of HIV infection. Also disclosed are processes for making said pharmaceutical compositions. |
US10842749B2 |
Compositions and methods of treating therapy resistant cancer and uses thereof
The present disclosure is directed to a composition for the sustained-release delivery of an active agent to a target cell of an individual. The compositions disclosed herein comprise of at least one porous particle; at least one polymer; and at least one active agent. In an embodiment, the porous particle comprises a plurality of microscale reservoirs. In an exemplary embodiment, the at least one active agent is covalently linked to the at least one polymer to form a polymer-active agent conjugate, and the polymer-active agent conjugate is contained in the plurality of microscale reservoirs of the porous particle. The present disclosure is also directed to a method of treating a tumor, comprising the step of administering to an individual the composition described supra. Additionally, disclosed herein is a method of eliminating tumor stem cells. Furthermore, there is provided a method of circumventing multi-drug resistance in a tumor cell. |
US10842748B2 |
Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography
The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
US10842743B2 |
Modified hyaluronic acid hydrogels and proteins for the time-controlled release of biologic agents
Hyaluronic acid-based hydrogels, solutions for preparing such, and methods pertaining thereunto are disclosed with properties that include self-resorption, extended release of biologically active agents, and/or decreased degradation, denaturation, and/or functional inactivation of biologically active agents. |
US10842741B2 |
Oral mucosa application material and method for producing same therefor
Provided is a novel oral mucosa application material that has good handling properties, has excellent application properties for being applied to the oral mucosa even if moisture or saliva on the surface of the oral mucosa is heavy, and is provided with a property for improving the effect of physically protecting an application site by containing the moisture or saliva after application and showing elasticity, and further, a property for remaining at the application site for a long time. This oral mucosa application material is provided with a freeze-dried body containing a polymer on an adhesion surface to the oral mucosa. The content of the polymer in the freeze-dried body is 20 mass % or more, and the content of hyaluronic acid in the polymer is 50 mass % or more. |
US10842732B2 |
Shellac based skin care lotion
The moisturizing properties of a water-based moisturizing composition containing one or more emollients emulsified in an aqueous carrier liquid are improved by including a water-soluble shellac in the composition. |
US10842728B2 |
Light-absorbing compositions and methods of use
The present disclosure relates to methods and compositions comprising naturally occurring light absorbing molecules for preventing damages from light exposure. Specific embodiments of this disclosure include fluorescent proteins from Brachiostoma lanceolatum. |
US10842724B2 |
Artificial saliva
A composition for mixing with water for use as an oral rinse, comprising monobasic sodium phosphate, dibasic sodium phosphate, sodium chloride, and calcium chloride. |
US10842722B2 |
Pump-type toothpaste composition
The present disclosure relates to a pump-type toothpaste composition capable of being provided as contained in a pumping type container, and to a pump-type toothpaste composition improving the spreading property to a tooth as the toothpaste composition discharged to a toothbrush penetrates into the toothbrush and having an effect of ultimately delivering a medicinal ingredient continuously for a long time in the oral cavity.In addition, the present disclosure relates to a pump-type toothpaste composition with excellent commercial value, which can ensure discharge stability without hardening and accordingly, can be used in a pump-type container equipped with a dispenser pump (dip pump), which has a remarkable problem of hardening in the discharge port due to free movement of external air because of properties of the container, and thus can ensure even the convenient use. |
US10842720B2 |
Dosage of foam comprising an anionic/zwitterionic surfactant mixture
Described herein is a dosage of foam including from about 7.5 cm3 to about 70 cm3 of the foam. The foam includes (a) from about 0.5 g to about 4 g of a detersive surfactant; (b) from about 0.001 g to about 4 g propellant; (c) a foam density of from about 0.05 g/cm3 to about 0.35 g/cm3; (d) a bubble size distribution having an R32 of from about 5 μm to about 100 μm; and (e) a β value of from about 0.0075 g/cm3 to about 0.1575 g/cm3. |
US10842715B2 |
Infusion accessory capable of detecting infusion liquid parameters and method of detecting infusion liquid parameters
Disclosed is an infusion accessory capable of detecting infusion liquid parameters, which is a lid body, comprising a first portion provided with one or more detecting members and a second portion having one or more liquid channels. Relative position changes may occur between the first portion and the second portion, the liquid channels and the detecting members may be switched between an open position and a closed position as position changes occur between the first portion and the second portion, the open position enables communication between the liquid channels and the detecting members so that liquid in the liquid channels may flow into the detecting members, the close position enables sealing between the liquid channels and the detecting members so that the liquid in the liquid channels cannot flow into the detecting members and the liquid that already flows into the detecting members cannot return to the liquid channels. |
US10842697B1 |
Disposable bio-secure environmental unit
A low cost, disposable bio-secure environment to temporarily hold, and where required to transport, patients who are suspected of having an infectious or contagious disease requiring contact, droplet and/or respiratory isolation precautions. The described Environmental Unit's unique design provides a unit that is disposable and relatively inexpensive. The frame is designed to integrate and adapt to various hospital stretchers and beds. The unit is large enough for a patient to sit up and allows movement of arms and legs and the ability to eat and drink while isolated on a bed. |
US10842696B1 |
Mobility strap device
Embodiments disclosed include devices for increasing bed mobility. A mobility strap apparatus includes a bed-strap; a fastening end coupled to the bed-strap; and a hand-grip coupled to the top surface of the bed-strap. Rigid affixing of the bed-strap to a bed provides stable support to users when moving or stabilizing oneself on a bed. A mobility strap grid provides a bed-strap configured to be longitudinally aligned with a bed; a bed-strap configured to be laterally aligned with the bed, intersecting and substantially perpendicular to the longitudinally aligned bed-strap; a fastening end coupled to a bed-strap; and a hand-grip coupled to the top surface of a bed-strap. |
US10842694B2 |
Patient support usable with bariatric patients
There is provided a patient support that may be adjustable in height, width, length or a combination thereof. The patient support may be useable with normal sized patients or with bariatric patients. The patient support has a variety of features to enhance operability and/or functionality, including a width adjustable caster frame, width adjustable deck portions, a width adjustable headboard and an extendible foot board to provide extra length. An enhanced lift mechanism can accommodate bariatric patients and alternative functionality in achieving deck positions improves patient comfort. Various parts of the patient support including deck panels and the footboard may be removed and replaced with ease without complicated connectors. |
US10842692B2 |
Elevatable and portable wheelchair
A wheelchair includes a lower assembly including a lower frame having wheels rotatably mounted thereto, an upper assembly including an upper frame supporting a seat, a backrest and at least one movable armrest, and a lift mechanism configured to move the upper assembly relative to the lower assembly between a lowered position and a raised position, wherein a user can move sideways out of the seat in the raised position with the movable armrest lowered. |
US10842690B2 |
Absorbent core with profiled distribution of absorbent material
An absorbent core for absorbent articles such as diapers comprising a core wrap comprising a top side and a bottom side, an absorbent material between the top side and the bottom side of the core wrap, a first and second longitudinally-extending channel-forming areas disposed on opposite sides of the longitudinal axis and substantially free of absorbent material preferably through which the top side of the core wrap is preferably attached to the bottom side of the core wrap. The core has a central absorbent zone between the first and the second channel-forming areas and a first and second lateral absorbent zones disposed laterally outwardly. The basis weight of the absorbent material in the central absorbent zone is higher than the basis weight of the absorbent material in each of the lateral absorbent zones for at least a first transversal section (S1). This relation is inverted along a second transversal section (S2) of the core. The first and second sections have each a length in the longitudinal direction of at least 10 mm. |
US10842688B2 |
Absorbent article with elevated skin-contacting topsheet layer
An absorbent article includes two planar liquid permeable topsheet layers with a first topsheet layer suspended from the longitudinal ends of the second topsheet layer. The first topsheet layer is of shorter length than the second topsheet layer such that the relaxed absorbent article includes a curvature along its length. The first topsheet layer defines a central opening and two end openings which allow for air circulation through the article and also for the second topsheet layer to be seen through the openings in the first topsheet layer. While the first topsheet layer is at least extensible, it is desirably elastic. |
US10842679B2 |
Body cast for the human body
An apparatus comprising a support wrap. The support wrap including at least an upper portion, the upper portion of said the support wrap having a first side extending along a first direction by a first length, the upper portion of said the support wrap having a second side extending along a second direction by a second length, the upper portion of said the support wrap having a third side extending along a third direction by a third length, the first direction is in a different direction than the second direction, the first direction is in a different direction than the third direction, the first length being greater than the second length, the first length being greater than the third length, the upper portion including a first upper fastening member, and said first upper fastening member capable of fastening said first side to said second side. |
US10842675B2 |
System and method for treating the structure of the human lens with a laser
A system and method for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a device for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern that utilize as series of shots that form a shell cut, a partial shell cut, a laser suture cut and/or a volumetric shaped removal, which essentially following the shape of asuture layer of the lens. |
US10842668B2 |
Gastroduodenal balloon tubes and methods for use in localized hypothermia
Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer). |
US10842666B2 |
Portable hypo/hyperthermia unit
A portable heating/cooling device for clinical hypo/hyperthermia with cuffs especially designed for arterial cooling/heating for raising or lowering the body temperature of a patient is operable by battery power or a wide range of available external power, and is usable in the field or in medical transport where such external power sources are not available. The small size, weight, and robust nature of the device allows it to be transported with the patient without the need for additional conveying devices. |
US10842661B1 |
Orthopedic thumb splint and method for stabilizing the trapeziometacarpal joint of a user
An orthopedic thumb splint is adapted for stabilizing a carpometacarpal joint of a user. The exemplary thumb splint includes a flexible fabric splint body having a wrist portion and a generally funnel-shaped thumb portion. The thumb portion defines a narrowed opening for receiving a thumb of the user. A thumb-abducting flexible X-strap is secured to the splint body adjacent the narrowed opening of the thumb portion. The X-strap has first and second diverging distal ends having respective inside surfaces. The inside surface of each distal end includes touch fasteners designed to releasably mate with complementary touch fasteners located on an outside surface of the splint body. |
US10842660B1 |
Lumbosacral spinal support, compression and treatment article
An improved lumbosacral wrap is generally provided. In an example, a lumbosacral wrap can include a lumbosacral panel, first and second bilateral panels, and a posterior pad. In certain examples, the lumbosacral wrap can include a wireless transcutaneous electrical nerve stimulation (TENS) device selectively supported by the lumbosacral panel or the posterior pad. In certain examples, the wireless TENS device is receivable within a cavity of a user engaging surface of the posterior pad in furtherance of supplementing support and compression of a lumbosacral spine with mobile treatment. |
US10842657B2 |
Braided stent crown geometry and flare
Disclosed herein is a stent which is compressible to small diameter and usable in neurovascular applications. The device is a braided stent and has a crown geometry which enables compression to small diameter without cracking or tangling. Also disclosed is a method of deploying a stent to a body vessel and its use in a coiling procedure. |
US10842654B2 |
Stent with segments capable of uncoupling during expansion
Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment. |
US10842653B2 |
Vacuum system for a prosthetic foot
A prosthetic foot comprising a vacuum system configured to attach to a vacuum attachment apparatus and a residual limb. The prosthetic foot may comprise a resilient bottom member, a resilient top member, and a vacuum system. The resilient bottom member may comprise a front end and a rear end. The resilient top member may comprise a front end and a rear end and the front end of the resilient top member may be connected to the front end of the resilient bottom member. The vacuum system may be coupled to an underside of the rear end of the top member. The vacuum system may comprise a compressible member, a chamber located within the compressible member, a valve system received within the compressible member, a passageway connecting the valve system and the chamber, and an air return coupled to the valve system and the vacuum attachment apparatus. |
US10842642B2 |
Methods and apparatus of performing spine surgery
Systems and methods are described for correcting sagittal imbalance in a spine including instruments for performing the controlled release of the anterior longitudinal ligament through a lateral access corridor and hyper-lordotic lateral implants with detachable fixation tabs. |
US10842638B2 |
Implants, systems and methods of using the same
Implants, device, systems and methods for replacing an articulation surface in a joint, for example, a glenoid implant with an articular surface and an opposing bone contacting surface having a ring and post extending therefrom that respectively mechanically connect with cortical bone and cancellous bone of a glenoid. Methods for implanting the glenoid implant are also disclosed. |
US10842634B2 |
Structural porous biomaterial and implant formed of same
An implant comprising a porous microstructure is disclosed which has an external surface, where at least a region of the external surface is formed of the porous microstructure. The microstructure is defined by at least one lattice of cells. Each cell has a predetermined cell topology and a plurality of edges. One or more of the edges of each cell connect to an adjacent cell along a corresponding edge thereof. Collectively, the cells have a periodic or aperiodic arrangement within the at least one lattice. |
US10842629B2 |
Active holder for annuloplasty ring delivery
An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle. |
US10842628B1 |
Heart valve support device
Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane. |
US10842621B2 |
Artificial cardiac valve
An artificial cardiac valve is disclosed, which includes an outer stent; an inner stent nested within and connected to the outer stent; leaflets disposed inside the inner stent; and membranes attached to walls of the outer and inner stents. The inner stent is a cylindrical mesh tube, and the outer stent includes a first stent segment, a second stent segment and a third stent segment which are connected sequentially. The first stent segment is a mesh tube. The second stent is a mesh tube having a substantially D-shaped cross-section, and the third stent segment is a flared mesh tube. The first stent segment has a maximum diameter that is equal to a diameter of the second stent segment and to a minimum diameter of the third stent segment. In this stent design, the inner stent can withstand traction forces from the leaflets, and the outer stent is adapted to match the anatomy of the native valve. As a result, after release, the artificial cardiac valve will seldom experience displacement and be rarely associated with paravalvular leaks. Moreover, it has a prolonged service life. |
US10842620B2 |
Systems and methods for anchoring and sealing a prosthetic heart valve
A method of implanting a prosthetic heart valve includes advancing a prosthetic heart valve to an implantation location within a patient's body, positioning the prosthetic heart valve within a native heart valve annulus, expanding a frame of the prosthetic heart valve from a first contracted configuration to a first expanded configuration, and then contracting the frame to a second contracted configuration. The prosthetic heart valve may be repositioned and then re-expanded from the second contracted configuration to a second expanded configuration. The prosthetic heart valve is preferably released from the delivery apparatus while in the second expanded configuration. Releasing the prosthetic heart valve from the delivery apparatus may result in radial expansion of a flange portion of the prosthetic heart valve. |
US10842617B2 |
Intraocular lenses having zone-by-zone step height control
A method and system provide an ophthalmic device. The ophthalmic device includes an ophthalmic lens having anterior surface, a posterior surface and at least one diffractive structure including a plurality of zones. The at least one diffractive structure is for at least one of the anterior surface and the posterior surface. Each zone includes at least one echelette having a least one step height. The step height(s) are individually optimized for each zone. To compensate chromatic aberration of eye from distance to a range of vision, a greater than 2π phase step height may be employed and the step height(s) folded by a phase, which is an integer multiple of two multiplied by π. Hence chromatic aberration of eye may be compensated to improve vision from distance to near. |
US10842615B2 |
Prosthetic capsular devices, systems, and methods
Prosthetic capsular devices (e.g., bag, bowl, housing, structure, cage, frame) include technology devices such as a computer, virtual reality device, display device, WiFi/internet access device, image receiving device, biometric sensor device, game device, image viewers or senders, GPSs, e-mail devices, combinations thereof, and/or the like. The technology devices can be used in combination with an intraocular lens. The output from the technology device(s) can be fed to the retina of the user to provide a visual image, can be otherwise connected to the user, and/or can be used to control the properties of the intraocular lens or of the prosthetic capsular device. Wearable technology that provides biometric data, such as blood glucose levels, body temperature, electrolyte balance, heart rate, EKG, EEG, intraocular pressure, sensing ciliary muscle contraction for accommodation stimulus, dynamic pupil change and retinal prostheses, combinations thereof, and the like can assist in technology-assisted health care functions. |
US10842613B2 |
Devices and methods for implantation procedures
Devices and methods of treatment useful in implantation and post-implantation procedures are described. The devices and methods may be used to correct deformities and/or asymmetries in tissues near an implant, support tissues near an implant, and/or refine the shape of an area of the body after placement of an implant, for example. The method may include inserting a cannula into tissue adjacent to or near an implant of a patient, and delivering fat or other filler material(s) to the tissue, wherein the cannula is configured to prevent or otherwise minimize the risk of damaging the implant, e.g., a breast implant. The cannula may include an elongate member having a lumen therein, an atraumatic distal tip, and an opening disposed proximal to the distal tip, the opening being in fluid communication with the lumen for delivering the fat or other filler material(s). |
US10842612B2 |
Breast treatment device
The present disclosure provides devices and methods for treating the breast. The devices can include an acellular tissue matrix having a predefined shape. The shape can include a first edge with an S-shaped configuration and a second arcuate-shaped edge. The shape alternatively can include a first concave edge and a second convex edge. |
US10842611B2 |
Tissue scaffold device and method for fabricating thereof
According to various embodiments, there is provided a tissue scaffold device including a porous core including a plurality of fibres; and an outer portion at least substantially surrounding the porous core, the outer portion including a plurality of pores elongated along a longitudinal axis of the tissue scaffold device. |
US10842610B2 |
Method for use of a double-structured tissue implant for treatment of tissue defects
A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects. |
US10842605B2 |
Prosthesis for repairing a hernia defect
A prosthesis for repairing a hernia defect includes a patch body, a hoisting frame releasably attachable to the patch body, and a tether attached to the hoisting frame with a free end extendable through the thickness of the patch body and accessible from the side of the patch body opposite to where the hoisting frame is releasably attached. The patch body and/or the hoisting frame includes a self-expanding support member. The hoisting frame includes a frame body with an outer frame component and a force translation component for directing pulling forces on the tether across the frame body. The outer frame component has a loop configuration to generally follow the patch periphery with overlapping end portions or a gap between free ends thereof. The force translation component is separable into multiple segments to facilitate withdrawal of the hoisting frame through an opening when released from the patch. |
US10842597B2 |
Fixed hybrid dental attachment assembly and methods of use
A frictionally-retained detachable dental attachment assembly or anchor device is designed to attach a dental appliance with a tooth root or implant. The assembly includes a denture attachment housing for securing in the dental appliance, an abutment attached with a tooth root or implant, and a compressible retention member with a first end in fixed attachment with the cap and a second end in snap engagement with the abutment via a frictionally-retained ball secured within a cavity of the abutment. The retention member is formed using a compressible material to allow the ball to compress and the retention member to flex while inserting the ball into the cavity. Additional friction-retained and fixed attachment configurations of the dental anchor device are provided, along with methods of securing a dental appliance in a subject's mouth by means of the friction-retained and fixed attachment dental anchor devices. |
US10842596B2 |
Orthodontic palatal and jaw expansion device that can be easily attached to/detached from inside the mouth
The present invention relates to a palatal and jaw expansion device comprising at least one screw, at least two blocks that are positioned on the screw so as to move on the screw, at least one stabilization rod whereon the blocks are seated, a movement mechanism disposed at the center of the screw and an arm that has a fixed end fixed to the movement mechanism perpendicularly to the horizontal axis where the screw extends and a free end and hat, when force is applied on the free end, rotates the movement mechanism whereon the arm is fixed and the screw around the horizontal axis where the screw extends, enabling the blocks to move on the screw. |
US10842595B2 |
Anterior guidance package, kit, and constructing method thereof
A method of constructing an anterior guidance package (AGP) equipped appliance, the AGP comprising a mandibular guidance component and a maxillary guidance component, and the appliance comprising a mandibular retentive piece configured to be placed about a mandibular arch of a user and a maxillary retentive piece configured to be placed about a maxillary arch of the user, the method comprising: maintaining of the mandibular guidance component in a correct orientation relative to the maxillary guidance component; indexing, while maintaining the mandibular guidance component in the correct orientation relative to the maxillary guidance component, the AGP onto the mandibular retentive piece and the maxillary retentive piece; and enabling, after indexing the AGP onto the mandibular and maxillary retentive pieces, the mandibular guidance component to move from the correct orientation relative to the maxillary guidance component. |
US10842589B2 |
Method for displaying an anatomical image of a coronary artery on a graphical user interface
A method for displaying an anatomical image of a coronary artery on a graphical user interface with information acquired from a plurality of intravascular image frames. The method may include detecting qualitative information from the plurality of intravascular image frames, creating one or more indicator(s) from the qualitative information detected, and determining a spatial relationship between the anatomical image and a plurality of acquisition locations of the plurality of intravascular image frames and generating its linear representation. The method also includes displaying the anatomical image of the coronary artery with the linear representation overlaid thereon on a display device and overlaying the one or more indicator(s) representing at least one type of qualitative information on the anatomical image along the linear representation. |
US10842588B2 |
Surgical instrument assembly
The invention comprises a surgical instrument assembly for minimally invasive surgery. The surgical instrument assembly comprises a light emitting arrangement and a surgical instrument. The surgical instrument has a distal end and a proximal end and comprises a handle portion at its proximal end and a grasper at its distal end, the grasper comprising at least two jaws and having a closed grasper position and an open position where a grasping space is formed between the jaws. The light emitting arrangement comprises a light source for generating light and a projector for projecting at least a beam of light comprising a string shape perpendicular to the optical axis of the beam of light. At least the projector of the light emitting arrangement is at least temporally fixed to the surgical instrument proximally to the jaws and is arranged to project the string shaped beam of light such that it will be broken upon a lateral movement of an object into the grasping space. |
US10842584B2 |
Component for a medical instrument and medical instrument
A component (14) for a medical instrument includes a shaft (15), a transmission device (16), which is movable in the shaft (15), for transmitting a force from a manipulation device (18) coupled to the proximal end of the component (14) to a tool (13) at the distal end of the component (14), an abutment surface (86) on the shaft (15), and an abutment surface (36) on the transmission device (16). The abutment surface (86) of the shaft (15) and the abutment surface (36) of the transmission device (16) are arranged such that a mechanical contact between the abutment surface (36) of the transmission device (16) and the abutment surface (86) of the shaft (15) limits a movement of the transmission device (16) relative to the shaft (15) in the proximal direction. |
US10842583B2 |
Medical kit and associated systems and methods for preventing central line associated blood stream infection
A medical kit 100 includes a drape 1323. A plurality of pockets (1302,1303,1304,1305, 1306,1307) are disposed along a bottom edge of the drape 1323 in a linear, side-by-side arrangement. A plurality of medical implements (1310,1311,1312,1313,1314,1315) are stowed in the plurality of pockets on a one-to-one basis. Medical indicia (1316,1317,1318,1319,1320,1321) is disposed along each pocket. The medical indicia can include comprising one or more educational prompts that instruct medical personnel how to use a particular medical implement disposed in a pocket to complete a central catheter dressing change. |
US10842572B1 |
Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines
Systems, devices, and methods for electroporation ablation therapy are disclosed. An apparatus may be configured to activate a field generator to generate an electric or magnetic field such that signals are received by a receiver coupled to an ablation device disposed adjacent to a tissue surface. Processed data associated with the signals may be obtained. A position and an orientation of the ablation device may be determined based on the processed data. An expected ablation zone of the ablation device in the tissue surface may be determined based on the position and the orientation of the ablation device. A map of the tissue surface and a visual representation of the expected ablation zone disposed in the map of the tissue surface may be displayed. |