最新美国发明专利第2020-03-17期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US10590472B2	Methods of detecting nucleic acids and applications thereof The present application provides simple, specific and sensitive methods for detecting a target nucleic acid in a biological sample, detecting a pathogen in a biological sample, and diagnosing a disease in an individual, utilizing a combination of nucleic acid hybridization-based capture and ligation-enabled PCR. The methods are particularly useful for detecting low level nucleic acids and pathogens and for automation and processing of multiple biological samples.
US10590467B2	Methods and kits for analyzing DNA binding moieties attached to DNA A method of analyzing DNA which, in a cell, is bound to a DNA binding moiety, the method comprising: (a) obtaining at least two samples of complexes of DNA bound to a DNA binding moiety; (b) isolating the complexes on a solid support; (c) labeling the DNA of the complexes, wherein the labeling distinguishes between the complexes of the first of the at least two samples and the complexes of the second of the at least two samples; (d) pooling the at least two samples of complexes; and (e) isolating the complexes using an agent which specifically binds to the DNA binding moiety; and (f) analyzing the DNA of the complexes.
US10590465B2	Enrichment of nucleic acids by complementary capture Assays can be used to detect mutations found in neoplasms of the pancreas, as well as for other neoplasms and other uses. Nucleic acids can be captured from body fluids such as cyst fluids. Thousands of oligonucleotides can be synthesized in parallel, amplified and ligated together. The ligated products can be further amplified. The amplified, ligated products are used to capture complementary DNA sequences, which can be analyzed, for example by massively parallel sequencing.
US10590464B2	Enhanced utilization of surface primers in clusters Presented herein are methods and compositions for enhancing utilization of surface primers during the surface amplification process. The methods are useful for surface amplification at improved densities. The methods and compositions provided herein enable creation of clusters which are brighter, but at the same densities as currently achieved using standard cluster amplification.
US10590462B2	Probes and assays for measuring E3 ligase activity Provided herein is technology relating to the biological process of protein ubiquitination and particularly, but not exclusively, to compositions and methods for studying protein ubiquitination and developing therapeutics to modulate protein ubiquitination.
US10590457B2	Compositions for cell culture and methods of using the same The present invention relates to new methods and processes for culturing mammalian cells with the addition of phenolic antioxidants. Performance of the cell culturing methods and processes in their various aspects result in a higher viable cell density and higher protein titer.
US10590455B2	Process for modifying galactosylation and G0F content of a glycoprotein composition by glutamine supplementation The invention relates to a cell culture process for decreasing the galactosylated content and/or increasing the G0F content of a glycoprotein. The process involves subjecting recombinant cells expressing the said glycoprotein to a temperature and pH shift and supplementing cell culture with glutamine.
US10590454B2	Methods of preventing and removing trisulfide bonds The present invention pertains to methods of preventing and eliminating trisulfide bonds in proteins such as antibodies. In one embodiment, trisulfide bonds in proteins are converted to disulfide bonds as part of chromatographic purification procedures. In another embodiment, the formation of trisulfide bonds in proteins is inhibited by implementation of methods described herein during the cell culture production of such proteins. In another embodiment, monoclonal antibodies are produced by the methods described herein.
US10590451B2	Methods of constructing a circular template and detecting DNA molecules A method of constructing a circular template includes preparing a partially double stranded linear DNA molecule, and incubating the partially double stranded linear DNA molecule with a ligase capable of intra-molecular ligation of single stranded DNA molecules to generate a partially double stranded circular DNA molecule. A method of detecting DNA molecules includes the following steps. Target DNA molecules are isolated with probes to form partially double stranded linear DNA molecules. The partially double stranded linear DNA molecules are incubated with ligases capable of intra-molecular ligation of single stranded DNA molecules to generate partially double stranded circular DNA molecules. A circular sequencing of the partially double stranded circular DNA molecules is conducted by using the probes as primers.
US10590448B2	Production of galacto-oligosaccharides The invention relates to the enzymatic preparation of galacto-oligosaccharides (GOS). Provided is a method for preparing GOS from lactose, comprising (i) contacting a lactose feed with immobilized beta-galactosidase (EC 3.2.1.23) and (ii) allowing for GOS synthesis, wherein said lactose feed is an aqueous slurry of crystalline lactose.
US10590445B2	Variant LovD polypeptides and their uses The present disclosure provides acyltransferases useful for synthesizing therapeutically important statin compound.
US10590441B2	Process for biofuel and biochemical production, culture medium and biofuel and biochemical produced The present invention relates to a process and a culture medium for biofuel and biochemical production by fermentation of lignocellulose biomass. The process describes the use of a solid-liquid mixed blend formed by solid fiber pulp, hydrolysate, and a polypeptide complex. The solid fiber pulp is partially degraded by the polypeptide complex allowing microbe immobilization and, at the same time, releasing substances that affect Clostridium quorum sensing pathways. The present process and culture medium allow the improvement of biofuels and biochemical production, as butanol and acetone in an industrial scale.
US10590440B2	Process for producing a fermentation product from a lignocellulose-containing material The present invention relates to the production of hydrolyzates from a lignocellulose-containing material, and to fermentation of the hydrolyzates. More specifically, the present invention relates to the detoxification of phenolic inhibitors and toxins formed during the processing of lignocellulose-containing material by enzymatically sulfating the phenolic inhibitors and toxins using aryl sulfotranseferases.
US10590435B2	Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.
US10590434B2	Highly inducible dual-promoter lentiviral TET-ON system The invention relates to expression systems useful for regulated expression of a gene of interest based on the constitutive expression of the original TetR repressor and the expression of the polynucleotide driven by a constitutive promoter operably linked to an operator sequence for a tetracycline operator sequence. The system can be provided as two different polynucleotides or as an all-in-one vector. The invention also relates to vectors, host cells and viral particles according to the invention as well as to the uses thereof for in vitro and in vivo production of products of interest or for therapy.
US10590433B2	Genomic insulator elements and uses thereof Provided herein are methods for identifying high potency genomic insulator elements that can be used in a vector composition e.g., that are useful for preventing unwanted expression of neighboring genes, such as proto-oncogenes, when administered to a subject in need thereof. Also provided herein are methods for treating disease and methods for administering a nucleic acid to a subject using such vectors.
US10590432B2	Plants having increased resistance to pathogens and method for producing said plants The invention relates to a plant having increased resistance to pathogens, wherein the protein SOBIR1 from Arabidopsis thaliana or a homologous protein, which is capable of interacting with at least one of the PRR receptor proteins RLP30 or RLP1, and at least one of the PRR receptor proteins RLP30 or RLP1 are overexpressed in comparison with the wild-type plant or are newly synthesized. The pathogens are preferably fungi, in particular from the genus Sclerotinia, and bacteria, in particular from the genus Xanthomonas. The invention further relates to a method for producing a plant having increased resistance to pathogens.
US10590430B2	Methods for increasing plant growth and yield by using an ictB sequence Compositions and methods for increasing plant growth for higher crop yield are provided. The methods involve the expression of at least one ictB coding sequence in a C4 plant of interest. Further provided are methods for expressing at least one ictB coding sequence and increasing the expression of at least one additional coding sequence of interest selected from CO2 assimilating sequences, such as those sequences involved in the Calvin Benson cycle, starch synthesis pathway, and C4 carbon shuttle in the plant. C4 plants expressing an ictB sequence are encompassed by the invention. Additionally, plants expressing an ictB sequence and those plants showing increased expression of a sequence of interest are encompassed by the invention. The expression of ictB in the C4 plant and the co-expression of ictB with this additional gene or genes results in yield gains.
US10590424B2	C5a binding nucleic acids The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5′ AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3′ [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2′-deoxyribonucleotides.
US10590420B2	Treatment of amyotrophic lateral sclerosis The invention relates to a method for the treatment of amyotrophic lateral sclerosis (ALS). Specifically, the invention implements the use of an antisense sequence adapted to affect alternative splicing in a human SOD1 pre-mRNA, thereby leading to the destruction of the skipped m RNA by the cell machinery.
US10590417B2	RNA ligand-displaying exosomes for specific delivery of therapeutics to cell by RNA nanotechnology Disclosed herein are compositions comprising extracellular vesicles, such as exosomes, displaying an RNA nanoparticle on its surface. The RNA nanoparticle can target the extracellular vesicle to a given cell via a targeting moiety. The extracellular vesicle can also comprise a functional moiety, which can be used in treatment or diagnostics.
US10590415B2	Engineered nucleic acid-targeting nucleic acids The present disclosure provides engineered Class 2 CRISPR-Cas-associated discontinuous first-stem nucleic-acid targeting nucleic acids, nucleoprotein complexes comprising these nucleic acids, and compositions thereof. Nucleic acid sequences encoding the Class 2 CRISPR-Cas-associated discontinuous first-stem nucleic-acid targeting nucleic acids, as well as expression cassettes, vectors and cells comprising such nucleic acid sequences, are described. Also, methods are disclosed for making and using the Class 2 CRISPR-Cas-associated discontinuous first-stem nucleic-acid targeting nucleic acids, nucleoprotein complexes comprising such nucleic acids, and compositions thereof.
US10590412B2	Compositions and methods for modulation nucleic acids through nonsense mediated decay Disclosed herein are compounds, compositions and methods for modulating the amount or activity of a target nucleic acid. In certain embodiments, the amount or activity of a target nucleic acid is modulated through nonsense mediated decay.
US10590408B2	Method and composition for biomolecule stabilization The present invention relates to biomolecule stabilization to provide biomolecules, such as sensitive polymerases, in a convenient ready-to-go format. The invention provides a method and composition in which non-ionic surfactant or detergents of the polyoxyethylene cetyl ether family are used, preferably a Brij reagent or a combination of Brij reagents.
US10590407B2	Asx-specific protein ligase The present invention is directed to enzymes having Asx-specific ligase and cyclase activity and to nucleic acids encoding those as well as methods of the manufacture of said enzymes. Further encompassed are methods and uses of these enzymes.
US10590406B2	Recombinant microorganisms exhibiting increased flux through a fermentation pathway The invention provides a recombinant, carboxydotrophic Clostridium bacterium that expresses one or more of pyruvate:ferredoxin oxidoreductase (EC 1.2.7.1), acetolactate synthase (EC 2.2.1.6), and acetolactate decarboxylase (EC 4.1.1.5). The invention further provides a method of producing a fermentation product by fermenting the recombinant bacterium in the presence of a gaseous substrate comprising CO to produce one or more of ethanol, butanol, isopropanol, isobutanol, higher alcohols, butanediol, 2,3-butanediol, succinate, isoprenoids, fatty acids, biopolymers, and mixtures thereof.
US10590403B2	Acinetobacter lysins Acinetobacter lysin polypeptides and variants peptides with killing activity against gram negative bacteria. Methods for treating bacterial infections or bacterial colonization using Acinetobacter lysin polypeptides.
US10590396B2	Ketoreductase polypeptides for the preparation of phenylephrine The disclosure relates to engineered ketoreductase polypeptides and processes of using the polypeptides for production of phenylephrine.
US10590395B2	Mutein, method for producing said mutein, gene encoding said mutein, recombinant vector and plant bearing said gene, method for controlling amount of mevalonic acid produced and amount of isoprenoid produced, method for controlling 3-hydroxy-3-methylglutaryl-CoA reductase activity Provided is a mutant protein obtained by mutating a specific amino acid residue of HMGR, a rate-limiting enzyme of isoprene monomer biosynthesis in the polyisoprenoid biosynthesis pathway. The present invention relates to a mutant protein, wherein at least one amino acid residue selected from the group consisting of amino acid residues at positions 91, 225, 257, 287, 339, 411, 470, 509 and 574 of the Arabidopsis thaliana 3-hydroxy-3-methylglutaryl CoA reductase shown by SEQ ID NO:1 and amino acid residues at positions corresponding to the foregoing in 3-hydroxy-3-methylglutaryl CoA reductase is deleted or replaced with another amino acid residue.
US10590393B2	Retinoic acid enhanced human stem cell derived blood brain barrier model In one embodiment, the present invention is a method of creating a fully-human blood-brain barrier (BBB) model, comprising the steps of (a) obtaining a mixture of neural cells and brain microvascular endothelial cells (BMECs), wherein the neural cells and BMECs that comprise the mixture were produced from the differentiation of human pluripotent stem cells (hPSCs); (b) purifying BMECs from the mixture of neural cells and BMECs of step (a); and (c) co-culturing the purified BMECs with a cell type selected from the group consisting of pericytes, astrocytes and differentiated neural progenitor cells (NPCs), wherein a blood brain barrier model is created.
US10590392B2	Generation of airway epithelial organoids from human pluripotent stem cells The technology described herein relates to methods and kits for directed differentation of primordial NKX2-1+ lung progenitors along proximal differentiation pathways into functional airway epithelial cells and airway organoids (“bronchospheres”) or along distal lineage pathways using modulation of Wnt signaling. Other aspects relate cell lines, methods, assays and kits comprising airway epithelial cells, and assays for diagnosing a disease that affects swelling of the bronchospheres, and/or for assessing genetic lesions and/or drugs for treating the the disease, where the disease is cystic fibrosis. Other aspects relate to personalized medicine and methods of treatment of cystic fibrosis using the airway epithelial cells.
US10590390B2	Method for proliferation of pancreatic progenitor cells The present invention relates to a method for preparing highly pure pancreatic progenitor cells by using pluripotent stem cells such as ES cells or iPS cells as a source, inducing their differentiation into pancreatic progenitor cells, and culturing and proliferating the pancreatic progenitor cells. Specifically, the present invention relates to a method for proliferation of pancreatic progenitor cells, comprising the step of culturing the pancreatic progenitor cells in a medium containing (i) an EGF signal transduction activator and/or an FGF signal transduction activator and (ii) a ROCK inhibitor.
US10590383B2	Methods for differentiating pluripotent cells Methods are provided, in some aspects, for differentiating pluripotent cells into midbrain dopaminergic (DA) neurons using a mono-SMAD inhibition or inhibition of SMAD signaling with only one SMAD inhibitor. In some embodiments, mono-SMAD inhibition utilizes a single inhibitor of bone morphogenic protein (BMP) for differentiating pluripotent cells into midbrain DA neurons.
US10590379B2	Filamentous fungal biomats, methods of their production and methods of their use A novel method of growing fungi is disclosed which uses an engineered artificial media and produces high density filamentous fungi biomats that can be harvested with a minimum of processing and from which fungal products such as antibiotics, proteins, and lipids can be isolated, the method resulting in lowered fungus cultivation costs for energy usage, oxygenation, water usage and waste stream production.
US10590375B2	Methods for controlling the growth of prokaryotic and eukaryotic cells The present disclosure relates to methods for control of cell growth rates where cell growth is measured in situ. The methods are applicable to bacterial cells, mammalian cells, non-mammalian eukaryotic cells, plant cells, yeast cells, fungi, and archea.
US10590370B2	Apparatus and method for aging liquids A rectangular or cylindrical container made of stainless steel or another liquid-impervious material has a plurality of openings formed in the side wall(s). Wooden boards, made of white oak or other wood for aging and flavoring beverages, are fitted over the openings and sealed so that their inside surfaces contact the liquid in the container. The inside surfaces have cross-grain cuts such as saw cuts or holes, which are used to enhance the infusion of beverage liquid into the wood to age the beverage rapidly and flavorfully. When one batch is finished, the used boards are removed and new ones are fitted into the openings and used to treat another batch. Instead of, or in addition to the boards over the side-wall openings, hollow wooden air boxes having external cross-grain cuts are positioned in the container.
US10590367B2	Protease variants and polynucleotides encoding same The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
US10590366B2	Opacifiers for detergent compositions Provided is a detergent composition that contains an opacifier with improved opacifying characteristics. The composition comprises an opacifier, a surfactant, a solvent, and optionally a builder, wherein the opacifier is an aqueous dispersion of voided latex particles have a composition as described herein.
US10590365B2	Compounds for a controlled release of active molecules The present invention relates to the field of perfumery. More particularly, it concerns compounds comprising at least one β-glucuronide moiety capable of liberating a perfuming alcohol. The present invention concerns also the use of said compounds in perfumery as well as the perfuming compositions or perfumed articles, in particular deodorants or antiperspirants comprising the invention's compounds.
US10590361B2	Process for preparing a hydrowax The invention provides a process for preparing a hydrowax comprising the steps of: (a) providing a hydrocarbonaceous feedstock which contains more than 4% by weight of hydrocarbons boiling in the range of from 550 to 800° C.; (b) hydrotreating the hydrocarbonaceous feedstock with a hydrotreating catalyst in the presence of a hydrogen-containing gas under hydrotreating conditions to obtain a hydrotreated product; (c) hydrocracking at least part of the hydrotreated product as obtained in step (b) with a hydrocracking catalyst in the presence of a hydrogen-containing gas under hydrocracking conditions to obtain a hydrocracked product, which hydrocracking catalyst contains a zeolitic component which is present in an amount of at least 14 wt %, based on the total weight of the hydrocracking catalyst, and wherein the volume ratio of the hydrotreating catalyst as used in step (b) and the hydrocracking catalyst is more than 1; and (d) recovering from the hydrocracked product as obtained in step (c) the hydrowax.
US10590359B2	Hydrothermally carbonized biomass formed via reactive twin-screw extrusion A biomass-derived thermosetting polymer material being a product of processing a biomass feed material via a twin screw extruder having a length extending between an inlet and an outlet. Hot water from a water heater is injected into at least one inlet along the length of the twin screw extruder, the at least one inlet generally corresponding with a pressure boundary within the twin screw extruder. A pressure-sustaining valve is connected between the length of the twin screw extruder and the outlet, with the valve being adjusted to produce the biomass-derived thermosetting polymer material.
US10590356B2	Integrated process for the preparation of compounds useful as fuel components The invention relates to an integrated process for the production of fuel components starting from materials of a biological origin which comprises: (A) transformation of glycerine into an alkoxy-propanediol having formula RO—CH2—CHOH—CH2OH, wherein R is a linear or branched C1-C8 alkyl, (B) transformation of glycerine into 1,2-propanediol CH3—CHOH—CH2OH, (C) dehydration of the 1,2-propanediol obtained in (B) to propionic aldehyde, (D) reaction of part of the propionic aldehyde obtained in (C) with the alkoxy-propanediol having formula RO—CH2—CHOH—CH2OH obtained in (A) to give an acetal having formula (a) wherein R is a linear or branched C1-C8 alkyl, (E) transformation of part of the propionic aldehyde obtained in (C) to a propionate having formula CH3—CH2—COOR′, wherein R′ is a linear or branched C1-C8 alkyl. Particular components for gasolines and/or diesel are also described.
US10590351B2	Process for using molybdenum and particulate carbon catalyst for slurry hydrocracking A process and catalyst is disclosed for converting heavy hydrocarbon feed into lighter hydrocarbon products using multifunctional catalysts. Multifunctional catalysts enable use of less expensive metal by substituting expensive metals for less expensive metals with no loss or superior performance in slurry hydrocracking. Less available and expensive ISM can be replaced effectively.
US10590350B2	Apparatuses and methods for energy efficient separations including refining of fuel products In various aspects, methods and apparatuses for liquid-liquid extraction are provided. In certain aspects, an emulsion can be formed by combining a feed stream, an extractant, and a surfactant. The feed stream comprises a plurality of distinct components including a first component to be removed therefrom. The feed stream may be selected from a group consisting of: a hydrocarbon feed stream and an azeotrope. Then, a portion of the first component is extracted from the feed stream (or emulsion) by contact with a superoleophobic and hygroscopic membrane filter that facilitates passage of the first component and extractant through the superoleophobic and hygroscopic membrane filter. A purified product is collected having the portion of the first component removed. Such methods are particularly useful for refining fuels and oils and separating azeotropes and other miscible component systems. Energy-efficient, continuous single unit operation apparatuses for conducting such separation techniques are also provided.
US10590347B2	Process for flocculating and dewatering oil sand mature fine tailings A process for dewatering oil sand fine tailings is provided and comprises a dispersion and floc build-up stage comprising in-line addition of a flocculent solution comprising an effective amount of flocculation reagent into a flow of the oil sand fine tailings; a gel stage wherein flocculated oil sand fine tailings is transported in-line and subjected to shear conditioning; a floc breakdown and water release stage wherein the flocculated oil sand fine tailings releases water and decreases in yield shear stress, while avoiding an oversheared zone; depositing the flocculated oil sand fine tailings onto a deposition area to form a deposit and to enable the release water to flow away from the deposit, preferably done in a pipeline reactor and managing shear according to yield stress and CST information and achieves enhanced dewatering.
US10590346B2	Efficient use of biomass in regenerative furnace firing Efficiency of a thermochemical regeneration combustion system is enhanced by incorporation of gaseous products from pyrolysis of fuel such as biomass.
US10590345B2	Emulsification of hydrophobic organophosphorous compounds An emulsion includes at least one polymeric surfactant, water and at least one organophosphorous compound. The emulsion may include from about 1% to about 40% of the polymeric surfactant and from about 40% to about 80% of the organophosphorous compound. The emulsion may further include at least one salt or additional surfactant. The at least one polymeric surfactant may include silicone-based surfactants, polyoxypropylene-based surfactants, graft copolymers of polysaccharides, and combinations thereof. The at least one polymeric surfactant may account for about 25% to about 100% by weight of the surfactant content in the emulsion and the at least one secondary surfactant, if present, may account for up to about 75% by weight of the surfactant content in the emulsion. The emulsion may have an average dispersed phase drop size of less than about 5 micron, or less than about 1 micron, after 6 months.
US10590344B2	Liquid crystal medium containing polymerisable compounds The present invention relates to a liquid crystal (LC) medium comprising polymerisable compounds, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in LC displays, and to LC displays comprising it.
US10590331B2	Mixed dimers from alpha-olefin sulfonic acids Mixed dimer and mixed oligomer compositions are disclosed. The mixed dimer compositions comprise a monosulfonated cross-dimer or a salt thereof. The monosulfonated cross-dimer is a reaction product of (a) an alpha-olefin sulfonic acid (AOS acid); and (b) an unsulfonated olefin, an unsulfonated olefin precursor, or a functionalized olefin. The mixed oligomer compositions comprise a mono- or polysulfonated cross-oligomer or a salt thereof. The mono- or polysulfonated cross-oligomer is a reaction product of (a) an AOS acid; and (b) an unsulfonated diolefin or an unsulfonated diolefin precursor. Various methods for making the mixed dimer or oligomer compositions are described. Salts of the mixed dimer and oligomer compositions are useful surfactants for foams used in oilfield and other applications. The foams have improved high-temperature stability when compared with foams from AOS dimer acid salts.
US10590329B2	Oil recovery process using an oil recovery composition of aqueous salt solution and dilute polymer for carbonate reservoirs An oil recovery composition of an aqueous solution of one or more salts and dilute polymer and processes for enhanced oil recovery using the oil recovery composition are provided. An oil recovery composition may include an aqueous solution of one or more salts having a salinity of about 5000 parts-per-million (ppm) to about 6000 ppm and a polymer having a concentration of 250 ppm to 500 ppm. The one or more salts may include sodium sulfate (Na2SO4). The polymer may include a copolymer of acrylamide and acrylamido tertiary butyl sulfonate (ATBS). The oil recovery compositions provided may be suited for enhancing oil recovery in carbonate reservoirs having in situ oil viscosities less than 3 centipoise (cP).
US10590320B2	Adhesive molecules To provide novel adhesive molecules. An adhesive molecule having an amino acid sequence of SEQ ID NO. 1, or an amino acid sequence including a conservative substitution, a deletion, an insertion and/or a modification in the sequence of SEQ ID NO. 1.
US10590319B2	High performance, thermally conductive surface mount (die attach) adhesives A composition including (a) 20 to 85 wt % of a thermally conductive silver component containing silver nano-particles having a particle diameter of 5 to 500 nanometers; (b) a polyorgano-silsesquioxane component, the polyorganosilsesquioxane component selected from the group consisting of (i) 0.5 to 12 wt % of a polyorganosilsesquioxane fine powder, (ii) 0.5 to 8 wt % of a copolymer powder containing an interlacing polymer network of (I) a polyorganosilsesquioxane and (II) a polydiorganosiloxane; and (iii) 0.5 to 12 wt % of a combination of the polyorgano-silsesquioxane fine powder and the copolymer powder; and (c) 3 to 12 wt % of a total solvent content in the form of (i) one or more solvents, (ii) a vehicle containing one or more solvents, or (iii) a combination thereof.
US10590318B2	Multi-part polyurethane compositions, articles thereof, and method of making A multi-part polyurethane composition is composed of a first part comprising a polyurethane prepolymer composition and a second part comprising a polyol having a hydroxyl functionality of 4 to 6, and a desiccant. The composition further comprises a plasticizer, wherein the plasticizer can be present in any one or more of the parts. A polyurethane is formed by mixing and curing the composition. The composition can be used as an adhesive for separatory devices, in particular for potting hollow fibers.
US10590316B2	Cycloaliphatic-based epoxy adhesive composition A new adhesive composition comprising a cycloaliphatic-based epoxy composition, which is particularly suitable for use as a structural adhesive in anchoring applications.
US10590313B2	Hot melt adhesive composition The present disclosure provides a composition. In an embodiment an adhesive composition is provided and includes A) a propylene based plastomer or elastomer (PBPE) comprising up to 10 wt % units derived from ethylene and having (i) a Koenig B-value less than 1.0; (ii) a total unsaturation per mole of propylene from 0.01% to 0.03%; (iii) a density from 0.870 g/cc to 0.890 g/cc; (iv) a melt viscosity at 177° C. from 800 mPa·s to 11,000 mPa·s; and (v) a weight average molecular weight from 20,000 to 50,000 g/mol; B) a tackifier; and C) a wax.
US10590310B2	Electrical debonding of PU hot melt adhesives by use of conductive inks The present invention relates to a method for reversibly bonding a first and a second substrate, wherein at least the first substrate is an electrically non-conductive substrate, the method comprising: coating the surface of the electrically non-conductive substrate(s) with a conductive ink; applying an electrically debondable hot melt adhesive composition to the conductive ink-coated surface of the first substrate and/or the second substrate; contacting the first and the second substrates such that the electrically debondable hot melt adhesive composition is interposed between the two substrates; allowing formation of an adhesive bond between the two substrates to provide bonded substrates; and optionally applying a voltage to the bonded substrates whereby adhesion at least one interface between the electrically debondable hot melt adhesive composition and a substrate surface is substantially weakened. Furthermore, the present invention relates to the bonded substrates thus obtained.
US10590309B2	Copolymers A polyacrylate-polyolefin copolymer and composition for volatile solvent-free coating comprising such compounds having the following structure: wherein “PO” is a polyolefin having a number average molecular weight of at least 300 g/mole, and “Ar” is selected from the group consisting of C6 to C20 aryls, a C7 to C32 alkylaryls, a C6 to C20 aryloxys, and halogen substituted C6 to C20 aryls and C7 to C32 alkylaryls, while the other variables are as described herein. The copolymers can be produced in an alkylation reaction between the desired polyacrylate and a vinyl/vinylidene-terminated polyolefin.
US10590305B2	Polyimide dry film and application thereof A polyimide dry film including a carrier and a polyimide layer and a method of using the same are provided. The polyimide layer contains (a) a polyimide precursor or soluble polyimide and (b) a solvent. The solvent includes a hydrophilic solvent and a hydrophobic solvent and a weight ratio of the hydrophilic solvent to the hydrophobic solvent is in the range of about 0.05 to about 2. The polyimide dry film of the present invention has water absorbability, is relatively stable even in the presence of water, and has a non-sticky surface. The resulting polyimide has excellent physical properties and can be used in a process in which water or an aqueous solution is involved to form a coverlay with excellent physical properties.
US10590304B2	Radiation curable aqueous dispersions An aqueous dispersion comprising a mixture of a first dispersion and a second dispersion, wherein the first dispersion comprises at least one (meth)acrylated pre-polymer (A), and the second dispersion comprises at least one thiol-functional compound (B). The aqueous dispersion optionally comprises at least one ethylenically unsaturated compound (C).
US10590303B2	Thermoplastic polyurethane compositions, articles, and methods thereof Disclosed herein are improved thermoplastic polyurethane compositions, articles, and related methods. These compositions include aliphatic thermoplastic polyurethanes having a hard segment content ranging from 57 percent to 80 percent by weight. The hard coat compositions have a Shore D hardness of at least 70 and can display an Elongation at Break test result at 25 degrees Celsius of at least 150 percent. These materials, when hardened, can serve decorative and/or protective functions while displaying both a high degree of elongation at moderate temperatures and high hardness.
US10590302B2	High solids, low viscosity urethane-linkage containing latex and method of production thereof A latex comprising a urethane linkage and having a high solids content and a low viscosity is described herein. Also described is a process for making the urethane linkage-containing latex wherein urethane linkage formation and emulsion polymerization take place in the same processing step.
US10590296B2	Piezoresistive ink, methods and uses thereof The present disclosure relates to a piezoresistive ink composition for sensors production. This ink, change linearly their electrical resistivity with an applied deformation and can easily recover when the external applied stress is released. The composition comprises flexible polymers as thermoplastic elastomers from the styrene-butadiene-styrene family (SBS, SEBS or others), nanostructures of carbon or metal, polar solvents and dispersive agents. With this ink, the user can print the sensor with any desired geometry and use different printing techniques, including drop casting, spray, screen and inkjet printing.
US10590286B2	Room-temperature-curable organopolysiloxane composition, and base member coated with cured object obtained from said composition Provided is a room temperature-curable organopolysiloxane composition for preventing aquatic organisms from adhering to and growing on an underwater structure. The composition comprises: (A) an organopolysiloxane represented by the following general formula (1) wherein R1 represents either a hydrogen atom or a monovalent hydrocarbon group that may have a substituent group, and n represents an integer of not smaller than 1; (B) a hydrolyzable organosilicon compound and/or a partial hydrolysis condensate thereof, represented by the following general formula (2) wherein R1 represents either a hydrogen atom or a monovalent hydrocarbon group that may have a substituent group, R2 represents either an alkyl group that may have a substituent group or a cycloalkyl group, and a represents an integer of 1 to 3; (C) a curing catalyst; and (G) a bleed oil.
US10590284B2	Formula and process for crosslinking antimicrobials to surfaces and polymers A process is described herein for applying antimicrobials to substrates to prevent the growth of biological agents. An antimicrobial-binder mixture is provided. The binder comprises guar gum, ammonium sulfate, urea, and methyl acryloid. The antimicrobial is an organo silane quarternary amine antimicrobial. The antimicrobial-binder mixture is ionized to comprise negatively charged particles. The antimicrobial-binder mixture is aerosolized to form fog. The fog is administered to the surface and dried.
US10590281B2	Powder coating material, coated article, and method for producing coated article The invention provides a powder coating material capable of forming a film excellent in metallic hue, concealing property and weather resistance. The powder coating material comprises the following fluororesin (A), the following resin (B) and the following pigment (C) as constituents thereof, wherein the content of the pigment (C) is from 0.7 to 23 mass %; Fluororesin (A): a fluororesin having a fluorine content of at least 10 mass %; Resin (B): a resin having a SP value larger than that of the fluororesin (A), and the difference between the SP value thereof and the SP value of the fluororesin (A) is at least 0.4 (J/cm3)1/2; Pigment (C): a pigment which is a metallic pigment covered with a covering material, and the SP value of the covering material exceeds the SP value of the fluororesin (A) and less than the SP value of the resin (B).
US10590280B2	Waterborne basecoat for use in vehicle refinish and methods of making the same A waterborne basecoat includes a rheology package having two or more rheology modifiers selected from the group of an ethylene vinyl acetate copolymer wax emulsion, an alkali swellable acrylic copolymer emulsion, a silicate layered clay, and a hydrophobically modified ethylene oxide urethane; a resin system comprising two or more waterborne dispersion resins selected from the group of a urethane-acrylic hybrid resin dispersion having a medium Tg of about 15 to about 35° C., a urethane modified Aldehyde/ketone emulsion having a high Tg of more than about 100° C., and a polyurethane dispersion having a low Tg of less than about −20° C., and a pigment. The pigment may be metallic or non-metallic and may be selected from organic or inorganic pigments. The rheology package and the resin package may be optimized to accommodate properties commonly associated with different types of known pigments.
US10590275B2	Leuco polymers as bluing agents in laundry care compositions A method of obtaining a leuco polymer, the method comprising the step of reacting a compound with a polymer to form the leuco polymer. The compound includes at least one leuco moiety and at least one electrophilic group. The polymer is comprised of co-monomers of an aryl dicarboxylate, an oxyalkyleneoxy and an oxypolyalkyleneoxy and the polymer comprises at least one moiety selected from the group consisting of hydroxy, sulfhydryl, primary amine and secondary amine. Laundry care compositions comprising the leuco polymer and methods of treating textiles with such laundry care compositions.
US10590274B2	Silicone composition, a cured silicone rubber product and a power cable The present invention provides a silicone composition comprising components (A) to (F); (A) 100 parts by mass of a raw rubber-like, at 25 degrees C., organopolysiloxane having at least two alkenyl groups each bonded to a silicon atom; (B) 5 to 100 parts by mass of silica powder having a specific surface area of 50 m2/g or more; (C) platinum or a platinum compound in an amount of 1 to 1,000 ppm by mass as a platinum atom, relative to the mass of component (A); (D) 0.01 to 5 parts by mass of a compound selected from an organic silicon compound having a nitrogen-containing organic group and an unsaturated hydrocarbon group, and benzotriazole and a derivative thereof; (E) an addition reaction curing agent other than said component (C), or an organic peroxide in an effective amount to cure the composition, and (F) 0.01 to 5 parts by mass of an aromatic hydrocarbon group-containing organopolysiloxane represented by the general formula (1) wherein a proportion of the number of the monovalent aromatic hydrocarbon group to the total number of the substituents R1, R2 and R3 is 41% or more and less than 46%.
US10590273B2	Polyarylene sulfide composition A polymer composition that comprises a polyarylene sulfide, inorganic fibers, an impact modifier, an organosilane compound, and a high molecular weight siloxane polymer is provided.
US10590268B2	Rubber composition and tire using same The present invention provides: a rubber composition prepared by mixing 60 to 100 parts by mass of a filler (B), 0.9 to 2.4 parts by mass of a phenol resin (C), 0.07 to 0.2 parts by mass of a methylene donor (D), 1.5 to 2.1 parts by mass of a thiuram based vulcanization accelerating agent (E), and 3.2 to 4.5 parts by mass of a sulfenamide based vulcanization accelerating agent (F), based on 100 parts by mass of the rubber component comprising 20 to 80% by mass of a modified conjugated diene based polymer (A), allowing the ride comfort in normal running to be satisfied in parallel with improvement in the run flat durability (durability in run flat running); and a tire comprising at least one member selected from the group consisting of a side reinforcing rubber layer and a bead filler using the rubber composition.
US10590267B2	Methods for preparing tire treads with advantageous wear characteristics A method for preparing a vulcanizable composition of matter, the method comprising mixing rubber, silica, silica coupling agent, a strong base, and nicotinamide to form a masterbatch, introducing a curative to the masterbatch, and mixing the curative into the masterbatch to form a vulcanizable composition of matter.
US10590261B2	Polymer interlayers comprising epoxidized vegetable oil An interlayer comprised of a thermoplastic resin, varying amounts of an epoxidized vegetable oil, and, optionally, a conventional plasticizer. The use of a thermoplastic resin, an epoxidized vegetable (plant) oil, and, optionally, a conventional plasticizer creates synergy allowing the flow of the interlayer to be increased without sacrificing other characteristics typically associated with an increased flow (e.g., increased blocking and creep, exudation, surface roughness formation, decreased mechanical strength, and decreased manufacturing capability). In this regard, the epoxidized vegetable oil acts as a flow improvement agent, resulting in a high-flow interlayer. As a result, a thinner interlayer can be utilized in forming multiple layer panels because the resulting thinner interlayer has improved flow properties.
US10590257B2	Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications The present invention provides moldable, fully scalable cellulose silica-based hydrogels for use as low-cost and safe carriers and aqueous viscosity modifiers in various industrial and medical applications.
US10590256B2	Black ceramic additives, pigments, and formulations Ceramic black materials for use as, or in, colorants, inks, pigments, dyes, additives and formulations utilizing these black materials. Black ceramics having silicon, oxygen and carbon, and methods of making these ceramics; formulations utilizing these black ceramics; and devices, structures and apparatus that have or utilize these formulations. Plastics, paints, inks, coatings, formulations, liquids and adhesives containing ceramic black materials, preferably polymer derived black ceramic materials, and in particular polysilocarb polymer derived ceramic materials.
US10590255B2	Vinyl acetate-ethylene copolymer emulsion and method for producing same The present invention relates to a method for producing a vinyl acetate-ethylene copolymer emulsion which has high preparation stability and compatibility between raw materials, has a small amount of residual monomers, and is capable of improving the durability of a preservative and product stability; and a vinyl acetate-ethylene copolymer emulsion which has excellent durability of preservative and product stability.
US10590249B2	Water-soluble films and their use in detergent packets Provided is a water soluble film, and detergent packets comprising the film as an encasing material. The film contains a (meth)acrylic polymer that is a blend of a hard polymer and a soft polymer, and a plasticizer.
US10590245B2	Polymerization coupled compounding process The present invention provides a process for preparing an improved compounded product and a compounded product prepared by that process.
US10590243B2	Cationic polyphosphazene compound, polyphosphazenes-drug conjugate compound and method for preparing same The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
US10590242B2	Method for producing hydrosilyl group-containing organic silicon resin A method for producing a hydrosilyl group-containing organic silicon resin of formula (6) in a solid form, wherein after formulae (1) to (3) are hydrolyzed in the presence of an acid catalyst, hydrolysis is carried out by adding hydrosilyl group-containing organic silicon compounds of formulae (4) and (5), followed by neutralization by a base catalyst with the amount thereof being more than a molar equivalent of the acid catalyst, and then by condensation. By so doing, deactivation amount of the hydrosilyl group can be reduced, so that the method for producing the hydrosilyl group-containing organic silicon resin, which is in a solid form without a solvent and to which a hydrosilyl group can be introduced quantitatively and in a large quantity, is provided, R13SiOSiR13 (1) R13SiX1 (2) SiX24 (3) HnR23-nSiOSiR23-nHn (4) HnR23-nSiX3 (5) (R13SiO1/2)a(HnR23-nSiO1/2)b(SiO2)c(R4SiO3/2)d (6).
US10590241B2	Two-dimensional polymers comprised of a combination of stiff and compliant molecular units A family of new and novel molecules for mechanically superior two-dimensional (2D) polymers is described herein. By combining stiff carbon-containing cyclic polymer nodal units with more compliant linear polymer bridge units in an ordered, 2D repeating molecular structure it is possible to tailor the mechanical properties of 2D polymers and their assemblies to provide high stiffness, strength, and toughness. Furthermore, the inherent dimensionality of 2D polymers and their ability to be stacked into ordered and chemically interactive ensembles gives them inherent benefits in a variety of barrier and structural applications over current stiff and strong linear polymer technologies.
US10590235B2	Process for the preparation of a polyester A polyester including ethylene 2,5-furandicarboxylate units is prepared in a process, where in an esterification step a 2,5-furandicarboxylate compound is reacted with ethylene glycol to form an ester composition, including components with 2-hydroxyethyl and 2,5-furandicarboxylate moieties; where in a polycondensation step the ester composition thus obtained is subjected to polycondensation at reduced pressure in the presence of a polycondensation catalyst to obtain a polycondensate; and where during the polycondensation step 2,5-furandicarboxylic acid is added to the ester composition.
US10590230B2	Polyurethanes, articles and coatings prepared therefrom and methods of making the same The present invention provides polyurethanes including a reaction product of components including: (a) an isocyanate functional urethane prepolymer comprising a reaction product of components including: (i) about 1 equivalent of at least one polyisocyanate; and (ii) about 0.1 to about 0.5 equivalents of at least one diol having 2 to 18 carbon atoms; and (b) about 0.05 to about 0.9 equivalents of at least one branched polyol having 4 to 18 carbon atoms and at least 3 hydroxyl groups; and (c) up to about 0.9 equivalents of at least one polyol different from branched polyol (b) and having 2 to 18 carbon atoms, wherein the reaction product components are essentially free of polyester polyol and polyether polyol; compositions, coatings and articles made therefrom and methods of making the same.
US10590227B2	Curable organic polymer comprising at least one acylurea unit, its preparation and use The present invention suggests a curable organic polymer comprising at least one acylurea unit represented by structural formula (I): Moreover, the present invention suggests a process for the preparation of said polymer and the use of said curable organic polymer for the preparation of a cured composition and for the preparation of hydroxyurethanes.
US10590225B2	Use of a silylated aromatic polyphenol derivative for the production of a phenol-aldehyde resin for reinforcement of a rubber composition An aromatic polyphenol derivative comprising at least one aromatic ring bearing at least two —O—Z groups in the meta position relative to one another, the two positions ortho to at least one of the —O—Z groups being unsubstituted, is used for the manufacture of a phenol-aldehyde resin for reinforcing a rubber composition. Each —O—Z group represents an —O—Si(R1R2R3) group with R1, R2, R3 representing, independently of one another, a hydrocarbon-based radical or a substituted hydrocarbon-based radical.
US10590224B2	Fluorinated block copolymers Described herein is a millable fluorinated block copolymer having at least one A block and at least one B block, wherein the A block is a semi-crystalline segment comprising repeating divalent monomeric units derived from TFE, HFP and VDF; and the B block is a segment comprising repeating dilvalent monomeric units derived from HFP and VDF; and wherein the millable fluorinated block copolymer has a modulus of 0.1 to 2.5 MPa at 100° C.
US10590223B2	Polyphenylene ether resin composition, prepreg, metal-clad laminate and printed wiring board A polyphenylene ether resin composition includes (A) a modified polyphenylene ether that is end-modified with a substituent having a carbon-carbon unsaturated double bond, and (B) a crosslinking agent having a carbon-carbon unsaturated double bond. The crosslinking agent serving as component (B) includes from 50 to 100 mass % of (B-1) divinylbenzene and (B-2) polybutadiene. Components (A) and (B) are included in a ratio therebetween, expressed as the mass ratio (A):(B), of from 65:35 to 95:5. Components (B-1) and (B-2) are included in a ratio therebetween, expressed as the mass ratio (B-1):(B-2), of from 1:100 to 1.5:1.
US10590220B2	Photoalignment materials having improved adhesion The present disclosure provides for new photoalignment (co)polymer materials which demonstrate improved adhesion to a substrate. The (co)polymeric structure includes at least one photochemically active chromophore and at least one adhesion promoter group. Articles of manufacture, optical elements, ophthalmic elements and liquid crystal cells which include at least one photoalignment layer made from the photoalignment (co)polymer materials and methods for formation are also disclosed.
US10590219B2	Retardation material-forming resin composition, orientation material, and retardation material A retardation material-forming resin composition for providing an orientation material that has high photoreaction efficiency and with which a polymerizable crystal can be aligned in a highly sensitive manner. A retardation material-forming resin composition being thermally curable wherein including a resin (component (A)) having a photo-aligning group to which a thermally reactive moiety is bonded directly or connected via a linking group; an orientation material obtained by use of the composition, and a retardation material formed by use of a cured film obtained from the composition.
US10590212B2	Multimodal and broad molecular weight high density polyethylene This invention relates to new multimodal and/or broad molecular weight high density polyethylene polymers. The polymers may be made in a single reactor, preferably a gas phase reactor using a dual catalyst system comprising a pyridyldiamido transition metal compound, a metallocene compound, a support, and optionally an activator.
US10590211B2	Method for producing solid catalyst component for olefin polymerization, olefin polymerization catalyst, method for producing olefin polymerization catalyst, and method for producing olefin polymer A method for producing a solid catalyst component includes bringing a magnesium compound, a titanium halide compound, and one or more internal electron donor compounds into contact with each other to effect a reaction; washing the resulting product with a first inert organic wash solvent that does not have reactivity with the titanium halide compound, and has a solubility parameter (SP) of 8.0 to 9.0; washing the resulting intermediate product in the absence of the titanium halide compound with a second inert organic wash solvent that includes a hydrocarbon compound and does not have reactivity with the titanium halide compound, but has a solubility parameter (SP) of more than 9.0; and washing the resulting product in the absence of the titanium halide compound with a third inert organic wash solvent that does not have reactivity with the titanium halide compound, and has a solubility parameter (SP) of less than 8.0.
US10590207B2	Process for isolating fucoidan and laminarin from live, harvested seaweed The present invention is directed to a process for obtaining at least one of fucoidan and laminarin from live, harvested seaweed, wherein the process comprises the steps of: (i) harvesting seaweed comprising fucoidan and laminarin to obtain live, harvested seaweed, wherein the live, harvested seaweed exudes to form an exudate solution; (ii) collecting the exudate solution from the live, harvested seaweed, wherein the fucoidan and laminarin are dissolved in the exudate solution; and (iii) separating the at least one of fucoidan or laminarin from the exudate solution.
US10590206B2	Inert format Described herein are, proteins comprising amino acid substitutions in at least one of a first and a second polypeptide chain. Furthermore, is described the uses and methods related to said proteins.
US10590205B2	Chimeric antigen receptor compositions Provided herein are compositions, which exhibit diagnostic capabilities and allow to rapidly add functionality to adoptive immunotherapy. The compositions include isolated nucleic acids encoding proteins including antibody regions capable of binding compounds including a peptidyl moiety (e.g., a meditope). The recombinant proteins provided herein are useful, inter alia, for a broad variety of therapeutic and diagnostic purposes. For example, the recombinant proteins provided herein including embodiments thereof may be used as non-invasive means to characterize chimeric antigen receptor (CAR) T cells before and/or during treatment of diseases (e.g., cancer).
US10590194B2	T cell receptors and immune therapy using the same The present invention pertains to antigen recognizing constructs against tumor associated antigens (TAA), in particular the TAA Serine protease inhibitor Kazal-type 2 (SPINK2). The invention in particular provides novel T cell receptor (TCR) based molecules which are selective and specific for the tumor expressed antigen of the invention. The TCR of the invention, and SPINK2 binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of SPINK2 expressing cancerous diseases. Further provided are nucleic acids encoding the antigen recognizing constructs of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen recognizing constructs and pharmaceutical compositions comprising the compounds of the invention.
US10590192B2	Midkine antibody The present disclosure is directed to isolated or recombinant proteins, such as antibodies, which bind to, and inhibit or reduce the function of, midkine (MK) and their use as therapeutic and/or diagnostic agents for midkine-related disorders. The present disclosure is also related to nucleic acid sequences which encode said proteins and their expression in recombinant host cells. In particular, the present disclosure is directed towards humanized antibodies derived from murine antibody IP14 which specifically bind to human MK.
US10590190B2	Anti-complement factor C1q antibodies and uses thereof The present invention provides anti-C1q antibodies and methods of using the same.
US10590188B2	Antibody The present invention provides an antibody which comprises a variable heavy (VH) chain comprising CDR1, CDR2 and CDR3, and/or a variable light (VL) chain comprising CDR1, CDR2 and CDR3, wherein the CDRs have the same amino acid sequence as those from a complete antibody isolated from a synovial tissue sample of rheumatoid arthritis patients, as listed in Tables 1 and 2 or Tables 1 A and 2 A.
US10590183B2	BSL2v2c2-Ig polypeptides The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.
US10590182B2	Binding-triggered transcriptional switches and methods of use thereof The present disclosure provides binding-triggered transcriptional switch polypeptides, nucleic acids comprising nucleotide sequences encoding the binding-triggered transcriptional switch polypeptides, and host cells genetically modified with the nucleic acids. The present disclosure also provides chimeric Notch receptor polypeptides, nucleic acids comprising nucleotide sequences encoding the chimeric Notch receptor polypeptides, and host cells transduced and/or genetically modified with the nucleic acids. The present disclosure provides transgenic organisms comprising a nucleic acid encoding a binding triggered transcriptional switch polypeptide and/or a chimeric Notch receptor polypeptide of the present disclosure. Binding triggered transcriptional switch polypeptides and chimeric Notch receptor polypeptides of the present disclosure are useful in a variety of applications, which are also provided.
US10590177B2	Modifications of cupredoxin derived peptides The present invention provides modified cupredoxin derived peptides with pharmacologic activity that have improved pharmacokinetic properties, and methods to use them to treat mammals suffering from various conditions related to the pharmacologic activities. Modifications of the cupredoxin derived peptides include amino acid sequence variants and structural derivations that increase the plasma half-life of the peptide, increase the specific activity of the pharmacologic activity, decrease immunogenicity, and decrease the biotransformation of the peptides. The modified cupredoxin derived peptides can be used in methods to treat mammals for cancer, conditions elated to inappropriate angiogenesis, viral and bacterial infections, and specifically HIV and malaria, conditions related to ephrin signaling, and to deliver cargo compounds, including diagnostic compounds, to cancer cells.
US10590176B2	Engineered programmable molecular scaffolds from porous protein crystals The present disclosure provides compositions and methods for preparing engineered porous protein crystals comprising at least one guest molecule.
US10590169B2	Compositions and methods for inhibiting CD279 interactions Methods and compositions for inhibiting and/or interfering with interactions between (1) programmed Death-1 protein (also known as CD279) and (2) programmed death-ligand 1 (PD-L1) and/or programmed death-ligand 2 (PD-L2) are disclosed. In addition, methods and compositions for increasing IL-2 levels in a cell, and methods and compositions for preventing, treating, or ameliorating the effects of cancer in a subject, are disclosed.
US10590168B2	Substrates for FLT3 kinase and uses thereof The invention provides kinase substrates and methods comprising their use.
US10590167B2	NMDA receptor modulators and prodrugs, salts, and uses thereof Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
US10590166B2	Peptides useable for treating cancer Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH—CH(CH2—SO3H)COOH or Arg-Gly-NH—CH(CH2—SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting integrins including but not necessarily limited to α5β1-Integrin, αvβ3-Integrin and αvβ5-Integrin, inhibiting cellular adhesion to RGD binding sites, preventing or treating viral or other microbial infections, inhibiting angiogenesis in tumors, retinal tissue or other tissues or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.
US10590160B2	Efficient synthesis of nicotinamide mononucleotide The invention provides a process for the preparation of nicotinamide mononucleotide having formula (I): The method involves the protection of nicotinamide riboside by ketalization, followed by phosphorylation and then deprotection to provide nicotinamide mononucleotide.
US10590158B2	Total synthesis of shishijimicin A and analogs thereof In one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.
US10590152B2	Pinene-based flame retardant compounds A pinene-based flame retardant compound, a process for forming a flame retardant polymer, and an article of manufacture comprising a material that contains a pinene-based flame retardant polymer are disclosed. The pinene-based flame retardant compound includes a pinene derivative core and at least one flame retardant substituent having a phosphorus-based moiety. The process for forming the flame retardant polymer includes obtaining pinene, forming a derivative of pinene, obtaining a phosphorus-based compound, reacting the phosphorus-based compound and the pinene derivative to form a pinene-based flame retardant compound, and incorporating the pinene-based flame retardant compound into a polymer to form the pinene-based flame retardant polymer.
US10590151B2	Silanes and curable compositions comprising said silanes The invention relates to silane compounds having the general formula (I): SiR1n(R2)4-n (I), as defined herein, to a method for preparing the silane compounds and use thereof as crosslinker or as adhesion promoter and to a curable composition comprising a reaction product of the at least one silane compound, at least one polyorganosiloxane, and at least one catalyst, and use thereof.
US10590149B2	Fluorosilicon nitrile compounds Novel fluorosilicon nitrile compounds, and methods of preparing them, are described. The fluorosilicon nitrile compounds are characterized by having a total of four substituents attached to a silicon atom, wherein one or two of the substituents are fluorine atoms, one or two of the substituents are cyanoalkyl groups, which are the same as or different from each other, and the remainder of the substituents, if any, are alkyl groups, which are the same as or different from each other.
US10590148B2	Silicone compounds comprising a ketone or aldehyde benefit agent moiety Silicone compounds, delivery compositions, compositions, packaged products and displays comprising such silicone compounds, and processes for making and using such benefit agent delivery compositions, compositions, packaged products and displays. Such compositions have improved deposition and retention properties that may impart improved benefit characteristics to a composition and/or situs.
US10590145B2	Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent The invention relates the tetrahydrothiopyranopyrimidine derivatives, the preparation, and the use thereof. The invention contained tetrahydrothiopyranopyrimidine derivatives, and pharmaceutical acceptable salt and prodrug with the formula I or II. Also described here are preparation of tetrahydrothiopyranopyrimidine derivatives, pharmaceutical compositions comprising these compounds as therapy and prevention for HIV.
US10590143B2	Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclohexane-1,3,5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, a cycloheptane-1,3-dione-2-yl, in which each cyclic dione is bridged by alkanediyl, or a derivative thereof (e.g. an enol ketone tautomer derivative thereof), wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is —O—R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or —CH2CH2OCH3. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the weeds and/or to the plants and/or to the locus thereof.
US10590137B2	Mercaptopurine hemihydrate Provided herein is a new mercaptopurine form, as a hemihydrate, and methods of making and using the same.
US10590136B2	Processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide Provided herein are processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide, alternatively named (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide, or a salt, solvate, hydrate, or isotopologue thereof.
US10590132B2	Selective estrogen receptor down-regulators The specification relates to compounds of Formula (I): and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cell proliferative disorders.
US10590121B2	Kinase inhibitors and methods for making and using Disclosed embodiments concern kinase inhibitors having a structure according to formula 1, such as interleukin receptor associated kinases (IRAK) inhibitors, and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent a kinase-associated disease or condition, particularly an IRAK-associated disease or condition.
US10590119B2	Furoxans as therapies for neurodegenerative disorders Furoxan compounds, compositions comprising the same, and methods of making and using the same, are described.
US10590110B2	Deuterated domperidone compositions, methods, and preparation Deuterated domperidone compositions, methods of synthesis, methods of use, and dosing formulations providing beneficial safety and other effects.
US10590109B2	Heterocyclic compounds used as FGFR inhibitors The present invention relates to a heterocyclic compound, a pharmaceutical composition containing the same, a preparation method thereof, and use thereof as a fibroblast growth factor receptor (FGFR) inhibitor. The compound is a heterocyclic compound as shown in Formula I, or a pharmaceutically acceptable salt, prodrug, solvent compound, polymorph, isomer or stable isotopic derivative thereof. The present invention further relates to use of the compound for the treatment or prevention of related diseases which are FGFR-mediated such as cancer, and a method for applying the compound to treat said diseases.
US10590106B2	Certain chemical entities, compositions, and methods Chemical entities that are quinoxaline kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
US10590104B2	Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.
US10590102B2	Crystalline fumarate salt of (S)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]methanone This disclosure relates to the crystalline fumarate salt of (S)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone. The disclosure also relates to pharmaceutical compositions comprising the crystalline fumarate salt of (S)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone. The disclosure also relates to methods of treating cancers comprising administering to a patient in need thereof the crystalline fumarate salt of (S)-[3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl] [3-hydroxy-3-(piperidin-2-yl) azetidin-1-yl]-methanone.
US10590099B1	Processes for producing beta-lactone with heterogenous catalysts The present invention is directed to processes from producing beta-lactone and beta-lactone derivatives using heterogenous catalysts. In preferred embodiments of the present invention, the processes comprise the steps: passing a feed stream comprising an epoxide reagent and a carbon monoxide reagent to a reaction zone; contacting the epoxide reagent and the carbon monoxide reagent with a heterogenous catalyst to produce a beta-lactone product in the reaction zone; and removing the beta-lactone product from the reaction zone. In preferred embodiments, the heterogenous catalyst comprises a solid support containing a cationic Lewis acid functional group and a metal carbonyl compound comprising at least one of anionic metal carbonyl compound or a neutral metal carbonyl compound. In certain preferred embodiments, the epoxide reagent and carbon monoxide reagent have a biobased content.
US10590097B2	Acesulfame potassium compositions and processes for producing same A process for producing acesulfame potassium, the process comprising the steps of providing a cyclizing agent composition comprising a cyclizing agent and a solvent and having an initial temperature, cooling the cyclizing agent composition to form a cooled cyclizing agent composition having a cooled temperature less than 35° C., reacting an acetoacetamide salt with the cyclizing agent in the cooled cyclizing agent composition to form a cyclic sulfur trioxide adduct composition comprising cyclic sulfur trioxide adduct; and, forming from the cyclic sulfur trioxide adduct in the cyclic sulfur trioxide adduct composition the finished acesulfame potassium composition comprising non-chlorinated acesulfame potassium and less than 39 wppm 5-chloro-acesulfame potassium. The cooled temperature is at least 2° C. less than the initial temperature.
US10590094B2	Aminothiazole derivatives useful as antiviral agents The invention relates to novel compounds of the Formula (I), to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.
US10590090B2	2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric SHP2 inhibitors The present disclosure is directed to inhibitors of SHP2, such as pyrazine compounds, and their use in the treatment of disease associated with SHP2 modulation, such as Noonan Syndrome, Leopard Syndrome, juvenile myelomonocytic leukemias, neuroblastoma, melanoma, acute myeloid leukemia and cancers of the breast, lung and colon. Also disclosed are pharmaceutical compositions comprising the same.
US10590086B2	Pharmaceutical compound Provided is a tryptophan-2,3-dioxygenase (TDO) and/or indoleamine-2,3-dioxygenase (IDO) inhibitor compound for use in medicine, which compound comprises formula (I) wherein X1, and X2 may be the same or different and each is independently selected from C, N, O and S; X3, X4, X5, and X6 may be the same or different and each is independently selected from C and N; each bond represented by a dotted line may be present or absent, provided that at least one such bond is present; R1, R2, R3, R4, R5 and R6 may be present or absent and may be the same or different and each is independently selected from H and a substituted or unsubstituted organic group, provided that the number of R1, R2, R3, R4, R5 and R6 groups present is such that the respective valencies of X1, X2, X3, X4, X5, and X6 are maintained; and wherein at least one of R5 and R6 comprises a group Y, wherein Y is a group having a formula selected from (II), (III), (IV), (V), (VI), (VII) wherein L may be present or absent, and may be a substituted or unsubstituted organic linking group; R31 and R32 may be the same or different and are selected from H and a substituted or unsubstituted organic group; each R34 may be the same or different and is selected from H and a substituted or unsubstituted organic group; R35 is selected from a substituted or unsubstituted alcohol group or ether group; each R36 may be the same or different and is selected from H and a substituted or unsubstituted organic group; X7 may be selected from C and N; X8, X9, X10, X11, X12, X13, X14, X15 and X16 may be the same or different and each is independently selected from C, N, O and S; each bond represented by a dotted line may be present or absent; and each R313 may be the same or different and is selected from H and a substituted or unsubstituted organic group.
US10590080B2	Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device A compound is represented by a formula (1) below, in which k is an integer of 0 or more, m is an integer of 1 or more, n is an integer of 2 or more. L is a substituted or unsubstituted aromatic hydrocarbon ring having 6 to 30 ring carbon atoms, CN is a cyano group, and D1 and D2 are each independently represented by one of a formula (2), a formula (3) and formula (3x) below, D1 and D2 being optionally mutually the same or different.
US10590078B2	Sodium channel blockers The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and use thereof. The compound represented by the Formula 1 or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof can be effectively used in the prevention or treatment of pains, for example, acute pain, chronic pain, pain from nervous disease, postoperative pain, migraine, arthralgia, neuropathy, nerve injury, diabetic neuropathy, neuropathic disease, epilepsy, arrhythmia, myotonia, ataxia, multiple sclerosis, irritable bowel syndrome, urinary incontinence, visceral pain, depression, erythromelalgia, paroxysmal extreme pain disorder (PEPD).
US10590077B2	TRPV4 antagonists The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
US10590074B2	Potent and selective inhibitors of monoamine transporters; method of making; and use thereof Disclosed herein are bisarylmethylthioacetamides and bisarylmethylthioethylamines useful as inhibitors of monoamine transporters. The compounds are potent and/or selective inhibitors of dopamine (DA), serotonin (5-HT), and/or norepinephrine (NE) reuptake via their respective transporters, DAT, SERT and NET. Also disclosed are methods for eliciting a wake-promoting or cognitive or attention enhancing effect and for treating substance use disorders, attention deficit (hyperactivity) disorder, depressive disorders, bipolar disorder or other neuropsychiatric disorders sleep disorders or cognitive impairment using the compounds.
US10590071B2	Process for the preparation of isosulfan blue Isosulfan blue and processes for the preparation thereof are provided. A process is also provided for preparation of the intermediate, 2-chlorobenzaldehyde-5-sulfonic acid, sodium salt of formula (2), used in the preparation thereof and a procedure for the isolation of benzaldehyde-2,5-disulfonic acid, di-sodium salt of the formula (3). Also provided is a process for the preparation of an isoleuco acid of formula (4), which upon oxidation gives rise to isosulfan blue of pharmaceutical grade which can be used for preparation of pharmaceutical formulations. The isolation and purification procedures provided in the process provide substantially pure isosulfan blue with HPLC purity 99.5% or greater.
US10590069B2	Pinene-derived diisocyanates A pinene-derived diisocyanate compound, a process for forming a pinene-derived diisocyanate compound, and an article of manufacture containing a polyurethane polymer are disclosed. The process for forming the pinene-derived diisocyanate compound includes oxidizing the pinene to form a pinene-derived ketone compound, converting the pinene-derived ketone compound to a diamine compound in subsequent reaction steps, and reacting the diamine compound with phosgene to form the pinene-derived diisocyanate compound. The polyurethane polymer is synthesized in a reaction between a pinene-derived diisocyanate compound and a polyol.
US10590064B2	Crystals of alanine N-acetic acid precursors, process to prepare them and their use The present invention relates to alanine N-acetic acid precursors of formula (i) COOM-CH(CH3)—NH—(CH2CN), wherein M is hydrogen (alanine N-monoacetonitrile), or (ii) COOM-CH(CH3)—N—(CH2CN)2, wherein 0 to 50% of all M is sodium or potassium and 50 to 100% of all M is hydrogen (alanine N,N-diacetonitrile and its partial sodium or potassium salts) comprising L-alanine to D-alanine in a range of from 75:25 to 50:50 (L:D), or (iii) COOM-CH(CH3)—N—(CH2CONH2)2, wherein M is hydrogen (alanine N,N-diacetamide), in the form of crystals, and relates to a process to prepare these precursors and their use, especially to give MGMA or MGDA.
US10590063B2	Compositions and methods for the treatment of fatty acid metabolism disorders Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject are provided.
US10590059B2	Compounds and synthetic methods for the preparation of retinoid X receptor-specific retinoids Provided herein are compounds useful for the preparation of compounds that have retinoid-like biological activity. Also provided herein are processes for the preparation of compounds that have retinoid-like biological activity.
US10590057B2	Isotopic fluorination and applications thereof Methods of C—H bond fluorination using non-heme manganese catalyst are described herein. For example, a method comprises providing a reaction mixture including a non-heme manganese catalyst, a substrate comprising an sp3 C—H bond and a fluorinating agent and converting the sp3 C—H bond to a C—F bond in the presence of the non-heme manganese catalyst or a derivative thereof.
US10590055B2	Glycerol derived material A method of producing a solid glycerol derived material includes the steps of combining glycerol with a metal oxide, the glycerol having a water content of between about 5 and 50%, and the rate of combination of the glycerol and the metal oxide and the amount of the metal oxide being selected so that at least part of the water present in the glycerol reacts with the metal oxide in an exothermic reaction and at least part is driven off by heat produced in the exothermic reaction to produce the solid glycerol derived material.
US10590050B2	Method for co-producing various alkenyl halides and hydrofluoroalkanes Disclosed is a method for co-producing various alkenyl halides and hydrofluoroalkanes: cis-1-chloro-3,3,3-trifluoropropene is introduced into a first reactor to carry out an isomerization reaction in the presence of a first catalyst, and the reaction product is rectified to obtain a product trans-1-chloro-3,3,3-trifluoropropene; and 30-70 wt % of trans-1-chloro-3,3,3-trifluoropropene and hydrogen fluoride are mixed and then introduced into a second reactor to carry out a reaction in the presence of a second catalyst to obtain a second reactor reaction product; the second reactor reaction product is introduced into a phase separator for separation, and the obtained organic phase is rectified to obtain the products trans-1,3,3,3-tetrafluoropropene, cis-1,3,3,3-tetrafluoropropene and 1,1,1,3,3-pentafluoropropane. The invention has the advantages of simple process, high efficiency, high operation flexibility, less investment and low energy consumption.
US10590043B2	Solvent management methods for gel production Embodiments of the present invention describe a method for continuous manufacture of a gel material comprising the steps of: forming a gel sheet by dispensing a gel precursor mixture onto a moving element; allowing gelation to occur to the gel precursor mixture; and cooling the formed gel with a cooling system, thereby reducing the rate of solvent evaporation therefrom.
US10590040B2	Macro-cement compositions, method of producing macro-cement and engineered forms of macro-cement, and multi-stage homogenization process for preparing cement based materials A macro-cement and associated methods useful for preparing pastes, mortars, concretes and other cement-based materials having high workability, high density, and high strength are disclosed. A method of producing a macro-cement includes cement, supplemental cementitious materials (SCM's), including siliceous submicron-sized particles and nano-sized particles, and polymers in the form of liquid or dry chemical admixtures for concrete. The cement mixture may be used for making ultra-high performance concrete (UHPC).
US10590039B2	Formulation and method for producing ultra-high-performance concretes A formulation and method for obtaining ultra-high performance concretes, which provide a concrete with good mechanical properties of, inter alia, traction, compression, deformation, durability, ductility and toughness, with reduced related costs.
US10590031B2	Method and system utilizing ellipsometry to detect corrosion on glass An ellipsometry system detects and/or identifies significant corrosion on glass, such as on soda-lime-silica based float glass. In certain example embodiments, there is provided a method and/or system using ellipsometry to detect and/or identify significant corrosion on soda-lime-silica based glass, so that such significantly corroded glass can be identified and not coated with a low-E coating and/or not used in applications where optical appearance is important. The ellipsometry system may be part of, or used in connection with, a sputtering apparatus/system for sputter-depositing low-E coatings on glass, so that whether to pass a piece of glass to the sputtering apparatus/system is based on whether significant corrosion is detected on the glass.
US10590027B2	High performance glass fiber composition, and glass fiber and composite material thereof Provided are a high performance glass fiber composition, and a glass fiber and a composite material thereof. The content, given in weight percentage, of each component of the glass fiber composition is as follows: 52-67% of SiO2, 12-24% of Al2O3, 0.05-4.5% of Sm2O3+Gd2O3, less than 2% of Li2O+Na2O+K2O, 10-24% of CaO+MgO+SrO, less than 16% of CaO, less than 13% of MgO, less than 3% of TiO2, and less than 1.5% of Fe2O3. The composition significantly improves the mechanical properties and the thermal stability of glass, significantly reduces the liquidus temperature and forming temperature of glass, and under equal conditions, significantly reduces the crystallisation rate of glass. The composition is particularly suitable for the tank furnace production of a high performance glass fiber having excellent thermal stability.
US10590026B2	Non-alkali glass substrate A technical object of the present invention is to devise an alkali-free glass substrate having high devitrification resistance and high heat resistance. In order to achieve the above-mentioned technical object, the alkali-free glass substrate of the present invention includes as a glass composition, in terms of mol %, 60% to 80% of SiO2, 8% to 25% of Al2O3, 0% to less than 3% of B2O3, 0% to less than 1% of Li2O+Na2O+K2O, 0% to 10% of MgO, 1% to 15% of CaO, 0% to 12% of SrO, 0% to 12% of BaO, 0% to less than 0.05% of As2O3, and 0% to less than 0.05% of Sb2O3, and has a thickness of from 0.05 mm to 0.7 mm, a strain point of 700° C. or more, and a β-OH value of less than 0.20/mm.
US10590024B2	Production method for multicore optical fiber There is provided a method for producing a multicore optical fiber while reducing the mass of a glass block to be connected to a common cladding tube. A production method for a multicore optical fiber includes in order, a preform forming step of forming a common cladding tube having a plurality of holes extending between a first end and a second end, an insertion step of inserting core rods in the holes in a state in which end portions of the core rods are recessed from the first end, a heat shrinkage step of reducing a diameter of the first end by heating, a sealing step of sealing the holes by connecting a glass block to the first end, and a drawing step of depressurizing insides of the holes from the second end and performing spinning from the first end while combining the common cladding tube and the core rods.
US10590019B2	Method and system for treating wastewater Methods and systems are provided herein for treating wastewater, such as wastewater from oil and natural gas production. Distilled water may be treated with bacteria and other micro-organisms to remove nitrogen compounds from the distilled water. The distilled water may be produced from pretreating and distilling wastewater. The treatment steps of the distilled water include subjecting the water to microbial action under both anoxic and aerobic conditions and employing a membrane bioreactor to further purify the water. The purified water is still further purified by either reverse osmosis or ion exchange systems.
US10590018B2	Method for forming aerobic granules, device for forming aerobic granules, method for treating wastewater, and device for treating wastewater Provided is a method for forming aerobic granules in which a semibatch reactor for forming granules is used, the method involving repeatedly carrying out an inflowing step for causing organic-matter-containing wastewater that includes organic matter to flow in, a biological treatment step for biologically treating substances to be treated in the organic-matter-containing drainage water by using microbial sludge, a settling step for allowing the microbial sludge to settle out, and a discharge step for discharging biologically treated water which has been biologically treated, wherein the reaction time is adjusted such that the value obtained by dividing the total cycle time by the reaction time and multiplying the resulting quotient by the ratio of the MLSS concentration to the BOD load charged into the semibatch reactor is within a range of 0.05 to 0.25 kgBOD/kgMLSS/d, and the sludge is drawn such that the sludge retention period is 5 to 25 days.
US10590017B2	System to reduce interface emulsion layer formation in an electrostatic dehydrator or desalter vessel through use of a low voltage electrostatic interface emulsion treatment system inside the vessel A system for separating the components of an incoming oil-water mixture includes two electrode sets, one set arranged to apply an electrostatic field to an oil layer residing within a separator vessel and the other set arranged to apply an electrostatic field to the interface emulsion layer residing within the separator vessel. The first set of electrodes is in communication with a high voltage power source that ranges from 1 to 60 kV; the second set of electrodes is in communication with a low voltage power source that is no greater than 5 kV. Each set of electrodes may also be in communication with a second voltage source to provide increased power to promote effective coalescence. The system may also include power electronics to produce a variable amplitude and a variable frequency voltage supply to one or both electrode sets.
US10590016B2	Storage and delivery for a water treatment system and method of using the same A system to increase the water recovery ratio and efficiently save water in a water treatment and delivery system, particularly for a water treatment system that may be used for water softening, and more particularly for a water treatment system that employs capacitive deionization technology. Stored product water is delivered without the implementation of an additional pump, and the stored product water is used to recover water in a storage tank without having to send water to drain.
US10590011B2	Solar still system and related water transportation apparatus There is provided a water transportation system comprising evaporation zones for converting water into water vapour; condensation zones for condensing the water vapour into condensed water, the condensation zones being in fluid communication with the evaporation zones; water vapour conduits adapted to enable the fluid communication of the water vapour between the evaporation zones and the condensation zones; condensed water conduits adapted to enable the fluid communication of condensed water between the condensation zones and the evaporation zones; wherein the evaporation zones and the condensation zones alternate in position along a water transportation path between a water source site and a water destination site for enabling the transport of water from the water source site to the water destination site through alternating processes of evaporation-condensation and condensation-evaporation of the water.
US10590007B2	Control of industrial water treatment via digital imaging Systems for and methods of monitoring and analyzing deposit in an industrial water system are provided. The methods comprise heating a substrate while the substrate contacts industrial water in the industrial water system to form deposit on the substrate. A series of digital images of the substrate while the substrate contacts the industrial water in the industrial water system is created. A region of interest in the series of digital images of the substrate is defined. A deposit feature in the region of interest in the series of digital images of the substrate is identified. The deposit feature in the region of interest in the series of digital images of the substrate is analyzed to determine a deposit trend of the substrate in the industrial water system. Generally, the systems are configured so as to be capable of carrying out one or more of the methods.
US10590004B2	Porous ceramic particles A porous ceramic particle has a porosity of 20% to 99%, and one principal surface of the porous ceramic particle is a mirror surface, and an aspect ratio thereof is greater than or equal to 3.
US10590000B1	High temperature, flexible aerogel composite and method of making same Aerogels, aerogel composites and methods of making the same are discussed. One example method can include the act of creating a boehmite colloid and adding a hydrolyzed silicon precursor to form a sol. A reinforcement can be infused with the sol and dried to form an aerogel composite. Such a method can also include the acts of performing one or more solvent exchanges and subjecting the gel composite to supercritical drying. Additionally, such a method can include the act of heat treating the aerogel composite. The aerogel composite can be used in high temperature, flexible seals capable of withstanding temperatures, pressures, and compression levels associated with aerodynamic heating generated during flight and in aerospace applications.
US10589999B2	Conversion of flue gas to valuable products A process is disclosed that converts flue gas carbon dioxide to liquid fuels with the aid of biomass and methane. This process incorporates biomass pyrolysis, and gasification of the renewable carbon obtained from this pyrolysis with carbon dioxide and methane in two separate gasification reactors. The gasification reactions occur optionally in the presence of microwave energy. Water, liquid fuels and a sequesterable carbon are expected to be the primary products in this carbon negative process.
US10589994B2	Burner and process for producing synthesis gas A burner for producing synthesis gas by partial oxidation of liquid or gaseous, carbon-containing fuels in the presence of an oxygen-containing oxidant and a moderator, which burner can be operated uncooled, i.e. without a fluid coolant being passed through the burner, is proposed. Steam or carbon dioxide or else mixtures of these materials are used as moderator. This is achieved by the feed channels being configured so that mixing of the fuel, the moderator and the oxidant occurs only outside the burner.
US10589993B2	Wafer-level package with enhanced performance The present disclosure relates to a wafer-level package that includes a first thinned die having a first device layer, a multilayer redistribution structure, a first mold compound, and a second mold compound. The multilayer redistribution structure includes redistribution interconnects that connect the first device layer to package contacts on a bottom surface of the multilayer redistribution structure. Herein, the connections between the redistribution interconnects and the first device layer are solder-free. The first mold compound resides over the multilayer redistribution structure and around the first thinned die, and extends beyond a top surface of the first thinned die to define an opening within the first mold compound and over the first thinned die. The second mold compound fills the opening and is in contact with the top surface of the first thinned die.
US10589992B2	Micro-electro-mechanical system (MEMS) structures and design structures Micro-Electro-Mechanical System (MEMS) structures, methods of manufacture and design structures are disclosed. The method includes forming a Micro-Electro-Mechanical System (MEMS) beam structure by venting both tungsten material and silicon material above and below the MEMS beam to form an upper cavity above the MEMS beam and a lower cavity structure below the MEMS beam.
US10589983B2	Silicon carbide microelectromechanical structure, device, and method Electromechanical device structures are provided, as well as methods for forming them. The device structures incorporate at least a first and second substrate separated by an interface material layer, where the first substrate comprises an anchor material structure and at least one suspended material structure, optionally a spring material structure, and optionally an electrostatic sense electrode. The device structures may be formed by methods that include providing an interface material layer on one or both of the first and second substrates, bonding the interface materials to the opposing first or second substrate or to the other interface material layer, followed by forming the suspended material structure by etching.
US10589982B2	Sensor package having a movable sensor A sensor package including a fixed frame, a moveable platform, elastic restoring members and a sensor chip is provided. The moveable platform is moved with respect to the fixed frame, and used to carry the sensor chip. The elastic restoring members are connected between the fixed frame and the moveable platform, and used to restore the moved moveable platform to an original position. The sensor chip is arranged on the elastic restoring members to send detected data via the elastic restoring members.
US10589980B2	Isolated protrusion/recession features in a micro electro mechanical system In described examples, a microelectromechanical system (MEMS) includes a first element and a second element. The first element is mounted on a substrate and has a first contact surface. The second element is mounted on the substrate and has a second contact surface that protrudes from the second element to form an acute contact surface. The first element and/or the second element is/are operable to move in: a first direction, such that the first contact surface comes in contact with the second contact surface; and a second direction, such that the second contact surface separates from the first contact surface.
US10589979B2	Fluid management controller A fluid management controller includes a processor, a wireless interface, and a memory. The wireless interface is configured to communicate between the processor and one or more fluid management components. The processor is configured to authorize control of the one or more fluid management components over the wireless interface. The memory is encoded with instructions that, when executed by the processor, cause the processor to provide dispense authorizations to the one or more fluid management components and record fluid dispense information from the one or more fluid management components in the memory.
US10589978B2	Beverage dispensers with dual flow dispensing valves A beverage dispensing valve includes a manifold that receives and dispense a first liquid and a second liquid. The manifold has a first flow channel through which the first liquid is conveyed and a second flow channel through which the second liquid is conveyed. A first shutoff assembly has a valve seal on a leg disposed in the first flow channel and a second shutoff assembly has a valve seal on a leg disposed in the second flow channel. A handle assembly is coupled to the first shutoff assembly and the second shutoff assembly and movement of the handle assembly simultaneously moves the leg of the first shutoff assembly and the leg of the second shutoff assembly into an open position such that the first liquid flows through the first flow channel, the second liquid flows through the second flow channel, and the first liquid and second liquid mix downstream to form a mixed beverage.
US10589977B2	Drinking water supply device and method of controlling the same A method of controlling a drinking water includes allowing a user to input a water discharge signal through an input lever, opening a first valve when a channel is closed by a water discharge valve to supply drinking water to a mixing tank, when the amount of drinking water supplied to the mixing tank reaches a first predetermined amount, opening a second valve to supply minerals to the mixing tank, and, when the amount of drinking water supplied to the mixing tank reaches a second predetermined amount, opening the water discharge valve to discharge mineral water to the outside through a spout.
US10589976B2	Filling system for filing packages A filling element for container filling includes a liquid-valve arrangement disposed in a liquid channel with its flow valve. A positioning drive regulates opening and closing of the flow valve so as to regulate flow of liquid through the liquid channel. A stop valve lies in the liquid channel between the flow valve and a dispensing opening.
US10589967B2	Drum assembly adapted to accommodate wire access lines of varying diameters One aspect of the disclosed subject matter is seen in a wire access line drum assembly that includes a tubular drum and an insert positionable therein to accommodate wire access lines of varying diameter. The tubular drum has a first and a second end and an inner and outer surface. The insert is positionable adjacent the first end of the tubular drum and has a curved channel formed therein extending between the inner and outer surfaces of the tubular drum. The insert has a ramp substantially coinciding with the outer surface of the drum at a first end portion and extending above the outer surface of the drum at a second end portion adjacent the curved channel. The height of the ramp at the second end portion is selected to be substantially similar to the diameter of the wire access line to be stored on the drum assembly.
US10589966B2	Jib coupling system for jib stowage A jib coupling system a stowage coupling assembly having a locking member movable between a retracted position and an extended position, an extension pivot coupling system having a coupling member movable between a retracted position and an extended position, and a cable having a first end operably connected to the locking member and a second end having a locking pin. Movement of the locking member from the extended position to the retracted position causes the locking pin to engage the coupling member, and movement of the locking member from the retracted position to the extended position causes the locking pin to disengage the coupling member. The jib coupling system may be implemented as a part of a boom assembly and on a boom assembly of a mobile crane.
US10589962B2	Elevator hoisting machine mounting device In an elevator hoisting machine mounting device, an elastic support device includes a supporting elastic body that deforms elastically upon reception of a load from a hoisting machine unit. A buckling suppression device disposed at a remove from the elastic support device in a horizontal direction includes first and second buckling suppression elastic bodies that sandwich, from above and below, a buckling suppression attachment portion provided on a lower portion of the hoisting machine unit, and a holding tool that holds the first and second buckling suppression elastic bodies on a machine base. The buckling suppression device suppresses, by an elastic restoring force of the first and second buckling suppression elastic bodies, buckling of the hoisting machine unit relative to the machine base due to the elastic deformation of the supporting elastic body.
US10589960B2	User device including secondary-touch elevator service request interface An elevator control system includes an elevator system with at least one elevator car configured to travel to a plurality of floors. An electronic controller controls the elevator system to deliver the elevator car to a given floor in response to an elevator car request. A mobile user includes a display screen and is installed with a secondary-touch detection system that detects a first touch action applied to the display screen and a second touch action applied to the display screen. The mobile user device launches a full service request user interface in response to detecting the first touch action, and performs at least one of launching a pop-up service request user interface and automatically communicates the elevator car request to the controller in response to detecting the second touch action.
US10589959B2	Driven reel trolley A driven reel trolley includes a carriage having a lower carriage section formed from opposing longitudinal members and transverse connecting members extending between and connecting the opposing longitudinal members. A pair of opposing support beams extend upwardly from the lower carriage. Each beam has a shaft support opening at about the top thereof for accommodating an associated shaft. A pair of non-driven wheels is mounted to the lower carriage section on opposing transverse sides of the lower carriage section and a pair of drive wheels is mounted to the lower carriage section, on opposing transverse sides of the lower carriage section, spaced from the non-driven wheels. A pair of drive trains operably connects the shaft and a respective one of the drive wheels. Each drive train includes a transmission and each transmission is operably engageable with and disengageable from the shaft and its respective drive wheel.
US10589957B2	Method of installing cable on cable reel A method of installing cable on a cable reel that has the steps of providing a cable reel that includes first and second opposing flanges where the first flange has a first hub portion and the second flange having a second hub portion and the first hub portion has one or more flexible segments; placing a cable coil over the first hub portion and on the first flange so that the first hub portion substantially extends through an inner diameter of the cable coil; and expanding the one or more flexible segments by inserting the second hub portion inside of the first hub portion so that the one or more flexible segments engage the cable coil.
US10589956B1	Retriever device and method A tether line is mounted in a retriever and, when a water vessel is launched into the water, the retriever applies a tension force to the tether line. After the water vessel is launched, the tension on the tether line pulls the water vessel from its launched floating position towards the stationary object. The retriever is rotatably mounted on the water vessel or the stationary object such that it will pivot around a vertical axis and point in a direction towards and along the tether line. A spool mounted on the structural unit holds the tether line, and an electrical or mechanical motor, such as a spring B-motor, places a torque on the spool and a tension on the tether line. After the water vessel is launched, the tension force from the motor pulls the water vessel from a launched position to the stationary object. A self-governing control mechanism in the retriever senses at least one operating parameter of the retriever and limits the retrieval of the tether line to within predetermined operating conditions. The self-governing control mechanism may sense the tension on the tether line and stop retrieval of the tether line when the tension on the tether line drops below a predetermined tension. The self-governing control mechanism may also (or alternatively) sense the speed of the spool and apply a brake force proportional to the spool's rotational speed.
US10589953B2	Reconfigurable diverter conveyor A conveyor includes a plurality of belt support assemblies each having a drive wheel assembly at one end and an idler wheel assembly at the other end. Each of the drive and idler wheel assemblies includes a motion converter for converting the rotational movement of a shaft into linear motion along the shaft and an actuator for selectively engaging the motion converter and the shaft. A controller controls the operation of the shafts and the actuators to selectively and individually control the location of each end of each belt assembly relative to one another and to a centerline of the conveyor.
US10589951B2	Method and system for removing outer layer of rollstock A method for removing outer layer of rollstock includes: first step of cutting rollstock's outermost circumferential film in a first cut portion, the rollstock formed by a film sheet rolled from base end to tip end and the tip end temporarily fixed to an outer circumferential surface; second step of cutting the film in a second cut portion closer to the base end than the first cut portion, a length from the tip end to the second cut portion being equal to or more than one round of the rollstock's outermost circumference; and step of discarding a first cut-film piece from the first cut portion to the tip end and a second cut-film piece from the first cut portion to the second cut portion by drawing the first and second pieces with a drawing device while driving an unwinding roller mounted with a hollow portion of the rollstock to rotate.
US10589950B2	Gravity-assisted wall registration system A gravity-assisted registration system suited to use in a printing device includes a transport member with a surface on which an associated sheet is translated in a process direction. The surface defines an angle with respect to horizontal in a cross-process direction. A registration wall, adjacent a lower end of the surface, defines a registration edge for registering the sheet. A drive mechanism drives at least one rotation mechanism, for translating sheet in the process direction, each rotation mechanism including at least one drive member with an axis of rotation parallel to the surface in the cross-process direction, Each drive member includes a sliding mechanism, at a periphery of the drive member, enabling the sheet to slide, under gravity, on the surface, toward the registration wall into an alignment position, in contact with the registration wall.
US10589949B2	Robotic manipulation using reusable, independent tags A system for robotic manipulation of objects having various shapes and sizes. The system includes a robot having an end effector, and an independent tag. The independent tag may have an object attachment interface to grasp an object, and an end effector attachment interface to mechanically interface with the end effector. Upon actuation of the robot, the end effector may move the object via the independent tag. A corresponding method is also disclosed and claimed herein.
US10589947B2	Apparatus for franking flat items of mail transported individually or from a supplied stack, such as envelopes, mailers, cards, printed products, sleeves, labels or the like, on a processing line An apparatus for franking flat items of mail removed individually or at the underside of a supplied stack and guided in a transport direction at one side edge, includes a separating station formed from a feeder for items of mail separating device, and a downstream processing line of a franking machine, following in a conveying manner in the transport direction, for franking/printing the individual items of mail. The processing line in the transport region between feeder and the separating device of the separating station assigned to the latter includes a plurality of driven transport rollers which form a transport plane for receiving an item of mail or the respective lowest item of mail from a stack, which rollers are mounted in a frame in the transport direction of the items of mail transversely and beside one another and in the same direction and at the same peripheral speed.
US10589945B2	Protective panel for shielding a dock pad A protective panel for shielding a dock pad while loading and unloading cargo includes a protective panel, a plurality of mounting holes, and a plurality of panel fasteners. The protective panel is mounted to a metallic door jamb of a loading dock via the plurality of panel fasteners. The plurality of mounting holes in turn allow the plurality of panel fasteners to attach to the protective pad. The protective panel includes a flat body and a curved body. The flat body protects the side of the dock pad, whereas the curved body protects the edge of the dock pad. As such, the flat body is connected adjacent to the curved body. Finally, each of the plurality of panel fasteners is attached to a corresponding hole from the plurality of mounting holes. Thus, the number of panel fasteners can be adjusted depending on the size and weight of the protective pad.
US10589944B2	Vehicle restraints with a barrier having rotational and translational motion Example vehicle restraints with a barrier having rotational and translational motion are described. An example vehicle restraint includes a carriage frame movable vertically relative to the dock. A drive shaft is supported by the carriage frame. A drive unit is to rotate the drive shaft about a shaft axis and relative to the carriage frame. A hub is connected to rotate with the drive shaft about the shaft axis, the hub having an outer diameter surface that is radially off center relative to the shaft axis. A barrier defines a bore that encircles the outer diameter surface of the hub. The barrier is movable selectively to an extended position and a retracted position. The barrier being connected to move selectively to the extended position and the retracted position in response to relative rotation between the outer diameter surface of the hub and the bore of the barrier.
US10589943B1	System and method for forming and moving an article array A system for forming and moving an article array including a consolidation area having a support surface for receiving and arranging rows of articles to form an article array from an article row delivery device while the consolidation area continuously stabilizingly supports the periphery of the article rows positioned on the support surface as the article rows are arranged to form the article array that is moved onto a transfer support surface for moving the article array toward a collection area.
US10589942B2	Article loading facility A control unit performs first loading control that is to be performed when a target article that has been determined by a determination unit as being an article that is in an appropriate orientation is to be loaded onto a first supporting member in the appropriate orientation, and second loading control that is to be performed when a target article that has been determined by the determination unit as being an article that is in an inappropriate orientation is to be loaded onto the first supporting member in the appropriate orientation. The first loading control is performed to control a loading operation unit to suck and support a first sucking-target surface of a target article that is supported by the second supporting member, from above, then move a sucking portion, and thereafter release the target article from the state of being sucked by the sucking portion, and the second loading control is performed to control the loading operation unit to perform an orientation changing operation, and thereafter release the target article from the state of being sucked by the sucking portion when the target article is located immediately above the first supporting member and the first sucking-target surface faces upward.
US10589939B2	Telescopic conveyor support assembly A support assembly for a telescopic conveyor may be provided. The assembly may include at least two spaced apart bearings and a reservoir of hydraulic fluid, the bearings being coupled to the reservoir to impart force to and receive force from the hydraulic fluid. The reservoir may be configured to transmit force received from any one of the bearings to at least one other of the bearings by the hydraulic fluid. The assembly can distribute uneven loads amongst the bearings thereby maintaining contact between the bearings and the conveyor, and reducing wear on the bearings and associated components.
US10589935B2	Motorized pulley and belt-drive system A motorized pulley mounted on a stationary shaft to drive a conveyor belt. The motorized pulley is constructed of an axial-flux motor in a housing connected to the motor's rotor. A driver including a drive ring has a drive surface mounted to the periphery of the housing to rotate with the rotor and the housing and drive a conveyor belt. The motor's stator is affixed to the shaft axially offset from the rotor.
US10589931B2	Hybrid modular storage fetching system A hybrid modular storage fetching system with a robot execution system (REX) is described. In an example implementation, a REX may induct, into the hybrid modular storage fetching system, an order identifying items to be fulfilled by automated guided vehicles (AGVs) at an order fulfillment facility. The REX may generate at task list including tasks for a first and second AGV, instruct the first AGV to retrieve a first item in the order from a first storage area based on the task list and deliver the first item to a pick-cell station. The REX may also instruct the second AGV to retrieve a second item of the order from a second storage area and deliver the second item to the pick-cell station. The REX may communicate with other components of the hybrid modular storage fetching system to coordinate the paths of the AGVs to fulfill the order.
US10589927B2	Waste disposal system A waste disposal device for sealing waste and a cassette for dispensing film are disclosed. The waste disposal device comprises first and second rollers, each comprising first and second end portions and a joining portion therebetween. The end portions of the first and second rollers are arranged to receive and seal first and second film portions therebetween as the first and second rollers rotate. The joining portions of the first and second rollers are arranged to define an aperture for receiving waste in a first rotary configuration of the rollers and to seal the first and second film portions therebetween in a second rotary configuration of the first and second rollers. The cassette comprises first and second portions comprising respective first and second film dispensers. The first portion is mechanically connected to the second portion. The cassette is moveable between a first, compact configuration and a second, extended configuration.
US10589925B2	Conveying systems A conveying system for conveying a conveyable material from a hopper where the system includes a fluid port located below the hopper outlet and in a vertical flow path into hopper outlet that can be momentarily opened for an on the go release of a charge of compressed air directly upward into the hopper outlet and into the underside of the bridge in the hopper to either disintegrate or unlock the bridged particles from each other thereby causing the bridged material to fall into the hopper outlet and into the conveying system where the material can be transported to a remote location or to remove any material that may be adhering to the wall during an emptying phase.
US10589923B2	Mobile erector system A mobile support structure (MSS) includes a frame structure for receiving modular silos, a base moveable between transportation and support configurations, and connectors coupling with the silos. A mobile erecting assembly includes a chassis, a lift structure rotatable between transportation and mounting orientations while engaged with a silo, an engagement structure movable between first and second positions while engaged with the silo, and an actuator to move the engagement structure and silo between the first and second positions. The silo is connected to the mobile erector assembly in the transportation orientation, and the mobile erector assembly is then aligned relative to the MSS, such as by engaging an alignment member of the mobile erector assembly with a chassis alignment post of the MSS. The mobile erector assembly is then operated to move the silo to the mounting orientation, and the silo is then coupled to the MSS.
US10589917B1	Resealable packaging device and method for packaging food product A packaging device incorporating a breathable peel/reseal film and enabling a preservation process for allowing for the distribution, storage and multiple servings of a food product, particularly perishable food product(s), and initiating and controlling the transmission rates, respiration rates or deterioration of the perishable food product(s) and thereby, maintaining good internal and external food quality and normal development of flavor and aroma characteristics. The packaging device includes a plurality of atmospheric control attributes that modulates or controls the atmosphere within the packaging device as the food product(s) respire in order to promote the extended shelf-life of the food product and the maintenance of the quality and desirable marketable characteristics of the food product. The atmospheric control attributes can include perforations that may be positioned in breathable peel/reseal film portion of the package to allow the product respiration for multiple servings without substantially altering the shelf life extension properties of the packaging device.
US10589915B2	Nested packaging for pharmaceutical products, and methods of distributing pharmaceutical products using same A pharmaceutical product can be distributed to respective patients in a plurality of jurisdictions. First and second jurisdictions can have different labeling requirements than each other. A plurality of inner containers each store the pharmaceutical product, the pharmaceutical product being in a dosage form and in a package approved by each jurisdiction of the plurality. An inner container can be sealed within a first outer container including labeling required by the first jurisdiction and not required by the second jurisdiction. Another inner container can be sealed within a second outer container including labeling required by the second jurisdiction and not required by the first jurisdiction. The sealed first and second outer containers respectively can be distributed to the first and second jurisdictions.
US10589909B2	Sift-resistant dispensing closure A sift-resistant dispensing closure is disclosed. The sift-resistant dispensing closure includes a base, a lid, and a hinge connecting the lid to the base. The base contains a circular end wall, a cylindrical skirt extending downward from the periphery of the end wall, and a sift deck elevated from the upside of the circular end wall. The sift deck contains a deck surface surrounded by a first snap bead and a first sealing surface, and pouring holes formed on the deck surface. The lid contains a second snap bead and a second sealing surface that are formed on the underside of the lid and engage with the first snap bead and first sealing surface, respectively, to form a seal around the sift deck when the lid is in a closed position.
US10589908B2	Pouring spout fitment for flexible container Flexible package fitments for use with detachable dispensing systems are provided. Pouring spout fitments configured to be attached to the inner surface of flexible containers are also provided. The detachable dispensing systems and pouring spout fitments include a hollow rigid member and an extendible spout disposed within and at least partially attached to the hollow rigid member and selectively positionable between a recessed position and, alternatively, an extended position, in which the extendible spout is configure to dispense a pourable material from the container through a distal opening when the fitment is attached to a flexible package. Material containers are also provided that include the fitments described herein.
US10589904B2	Flexible packaging with a straining feature Embodiments of a flexible pouch (1) comprise a pouch body (10), a collapsible perforated folded panel (50), an opening seal (60) disposed between the collapsible perforated folded panel (50) and the second ends (18, 19) of a front wall (12) and a rear wall (14), wherein the opening seal (60) adheres the second end (18) of the front wall (12) to the second end (19) of the rear wall (14) which thereby conceals the collapsible perforated folded panel (50). The release or removal of the opening seal (60) is operable to expose the collapsible perforated folded panel (50) and application of a pull force is operable to outwardly expand the collapsible perforated folded panel (50) to allow draining of liquid or dispensing of dry powder or flakes from the pouch chamber (52).
US10589903B2	Package or product and a package or product roll The invention relates to a package or product comprising at least one space for contents or objects, formed of at least one flexible part, which is a flexible pouch type container part, and to the at least one flexible part attached at least one stiff support part, in which the at least one stiff support part forms in opened position at least part of wall structure of the package or product. The at least one flexible part and the at least one stiff support part form the at least one space for the objects or contents, when the stiff material of the support part is bent and/or the package is opened at the stiff support part. The invention also relates to a package or product roll.
US10589897B1	Roto molded pallet Certain embodiments of the present disclosure describe a pallet assembly having a support assembly and a stringer. The support assembly includes a deck and a plurality of blocks that extend from the deck. The deck and the blocks are unitarily formed to create a contiguous outer shell that defines a common internal space that is filled with a support material. The blocks include extension portions that correspond to openings defined in the stringer. The extensions are received in a corresponding opening to attach the stringer to the support assembly.
US10589895B2	Spout assembly and packaging container A spout assembly with a spout and a cap. The spout has a cylindrical sidewall; a cylindrical base at the lower end of the sidewall and having a larger outer diameter than the sidewall; and a disk-like flange extending outward from the lower end of the base. The cap has a cylindrical peripheral wall with an internal thread and is screwed onto the upper end side of the spout sidewall. The spout sidewall also has a projection formed between the external thread and the recess so as to extend circumferentially and have a height lower than a height of the external thread, and with the cap screwed onto the spout, at least a portion of an upper surface of the base fits an inner side of a peripheral wall of the cap.
US10589893B2	Multi-sided reinforced container A multi-sided container has more than four sides and foldable panels integrally arranged with respect to each other. A first panel and a second panel form a contiguity with a first fold line disposed therebetween. The first panel and a third panel form a contiguity with a second fold line disposed therebetween. The third panel is not parallel with and not orthogonal to the first panel. A first strength reinforcement feature includes a first slot having a first planar edge oriented orthogonal to the first panel and orthogonal to a z-axis, and a second planar edge oriented orthogonal to the second panel and parallel to the z-axis. The third panel includes a cut edge proximate the first fold line having a third planar edge oriented orthogonal to the third panel and orthogonal to the z-axis. The third planar edge is disposed in a same plane as the first planar edge.
US10589892B2	Packet for french fries and a plano for assembling such packet A packet (10) for french fries comprising a bottom (11), side walls, a front- and a back-wall (12) and a closable lid (13), which packet has a total surface area and is provided with perforations (8, 8′) that collectively have an open area which is set at a preselected ratio of the total surface area, wherein said perforations are provided in the lid and in the front- and back-wall. The packet is made from a one-piece plano (1) comprising a connecting member (2) that connects on opposite sides of said member to a first and a second side member (3, 4). The first and the second side member are each tapering with an increasing width with increasing distance from the connecting member, wherein said width is measured perpendicularly to a body axis (5) extending through the first and second side member and the connecting member.
US10589891B2	Apparatus, system and methods for a fold down multiple cavity divider An improved collapsible container configured with a base member and at least one multiple cavity or compartment divider either permanently or removably attached to the base member at a pivot point. The multiple cavity divider is configured to close into a relatively flat portion that can be rotated about the pivot point and positioned against the base portion in a storage state, and the multiple cavity divider is configured to be expanded into an open position about the pivot point to create a number of separate cavities. Further, the base member is configured to provide support for the bottom of each of the cavities when the multiple cavity divider is in the expanded position, and the base member is configured to provide support for the multiple cavity divider when it is in the fold down or storage position.
US10589890B2	Container and method for producing a container A container of paper or paper-like material, having a sleeve and having a bottom and/or a cover, wherein the bottom and/or cover and the sleeve are connected in substantially liquid-tight fashion in the region of a bottom skirt and/or cover skirt. The sleeve is composed of a sheetlike blank, and wherein regions adjoining a first side edge and adjoining a second side edge, situated opposite the first side edge, of the blank are laid one on top of the other so as to form an overlapping side seam and connected to one another by material-bonding engagement, wherein at least the region adjoining the first side edge forms a step which is offset relative to the rest of the blank.
US10589887B2	Filling device A filling device for decanting material from a flexible bulk material container is provided. The filling device has a hollow body that has an upper opening face and a lower opening face. The upper end of the hollow body projects into the interior of the flexible bulk material container so that material from the flexible bulk material container can enter the hollow body via the upper opening face. At the lower end of the hollow body there is a closure that has an upper plate and a lower plate. The lower plate can be pivoted about the axis of a bolt from a first position in which it completely closes the opening of the upper plate to a second position in which the opening of the upper plate is at least slightly open. The lower plate has a structure that forms at least part of the standing face.
US10589881B2	Device and method for packaging flowable materials Apparatus and method for filling flowable materials such as fluids and bulk goods into flexible open-mouth bags, the apparatus including a stationary part and a movable part wherein the movable part is provided with multiple filling stations. Each filling station has a retaining device fastened to the movable part. A plurality of handling stations are received and distributed at the stationary part. A handling station is configured to take over empty open-mouth bags and a handling station is configured for filling a bag. One handling station is provided with a weighing unit. A bag receiving unit is configured to receive and guide the bag. The bag receiving unit at the handling station equipped with a weighing unit can be temporarily decoupled from force transmission to the retaining device to enable separate weighing of the bag receiving unit with the bag.
US10589880B2	Passive device designed to facilitate demise of a space system during re-entry into the earth's atmosphere Space system comprising a structure formed by structure components, an on-board equipment carried by the structure, and a passive device designed to facilitate demise of the space system during re-entry into the Earth's atmosphere. The passive device comprises connecting members designed to stably connect the structure components. The connecting members comprise at least a portion made of a primer material with characteristics such as to decay at re-entry altitudes higher than those at which the current connecting members melt so as to make unstable the connection created by the connecting members to such an extent as to early triggering demise of the structure of the space system during re-entry into the Earth's atmosphere.
US10589879B2	Cross-feeding propellant between stacked spacecraft A first spacecraft and a second spacecraft are configured to be disposed together, in a launch configuration, for launch by a single launch vehicle. In the launch configuration, the first spacecraft is mechanically coupled with a primary payload adapter of the launch vehicle, and the second spacecraft is mechanically coupled with the first spacecraft by way of an inter-spacecraft coupling arrangement. The spacecraft are configured to be deployed, following injection into a first orbit by the launch vehicle, by separating the first spacecraft from the primary payload adapter while the second spacecraft is mechanically coupled with the first spacecraft. A first onboard propulsion subsystem of the first spacecraft includes one or more thrusters configured to execute an orbit transfer maneuver from the first orbit to a second orbit. A propellant line arrangement detachably couples the first onboard propulsion subsystem with a second propellant storage arrangement on the second spacecraft.
US10589878B2	Additively manufactured reinforced structure A grid stiffened structure which includes a wall which extends in a direction transverse relative to a plane and an elongated rib connected along an elongated dimension of the rib to the wall such that the elongated rib extends along the wall and forms an angle with an axis which extends in a direction perpendicular to the plane. The elongated rib defines a free sidewall which extends from the wall positioned on a first side of the elongated rib and extends in a direction about the elongated rib and transverse to the elongated dimension to the wall positioned on a second side of the elongated rib. The wall and the elongated rib are constructed of a plurality of layers of material which extend in a direction transverse to the axis.
US10589871B2	Prognostic health monitoring and jam detection for use with an aircraft A method of prognostic health monitoring is provided for use with an aircraft. The method includes generating torque for controlling positions of controllable surfaces at right- and left-hand-sides (RHS and LHS) of the aircraft in a power drive unit (PDU) based on torque-limiter (TL) thresholds, performing real-time monitoring of the torque at the RHS and LHS of the aircraft, generating RHS and LHS torque information from results of the performing of the real-time monitoring, analyzing the RHS and LHS torque information and controlling operations of the PDU based on results of the analysis by at least one of modifying, tuning and defining the TL thresholds.
US10589869B2	Nacelle inlet lip fuse structure An inlet lip structure includes: an annular inner barrel with forward and aft ends; an annular outer barrel with forward and aft ends; an annular aft bulkhead interconnecting the aft ends of the inner and outer barrels; an annular forward bulkhead interconnecting the forward ends of the inner and outer barrels; an annular lip skin interconnecting the forward ends of the inner and outer barrels, the lip skin having a C-shaped cross-section comprising a nose with inner and outer legs extending therefrom, the lip skin having opposed inner and outer surfaces; and wherein the outer leg of the lip skin incorporates a fuse element having an ultimate strength which is lower than an ultimate strength of the remainder of the lip skin.
US10589868B2	Nacelle cowl tangential restraint Systems and methods are provided for an aircraft propulsor with a fan cowl with one or more tangential restraints. The tangential restraints may be configured to contact one or more tangential receiving portions of a fixed portion of the aircraft propulsor. The fan cowl may receive a load that may include a bending load. The tangential restraints may be configured to convert the bending load to membrane tension and thus decrease deflection of the fan cowl.
US10589867B2	Gimbaled thruster configuration for use with unmanned aerial vehicle A vectored thrust control module for an aircraft that includes a servo system that couples to the aircraft structure at an output shaft connection point. A thrust motor assembly is fully supported by the servo system and rotates a bladed component to provide thrust to the aircraft. Further, the thrust motor assembly is rigidly connected with the servo system to rotate together about a longitudinal axis thrust line with respect to the aircraft structure. The bladed component and the thrust motor assembly generate a line of thrust that extends through the connection point of the servo system to the aircraft structure.
US10589861B2	Drone control system, method, and program A drone control system in which a drone can move to a position where a purpose can be achieved and performs an action according to the purpose is provided. The drone control system 1 controls a drone 10 capable of performing a predetermined action on a predetermined object, and includes a state data acquiring module 201 that acquires state data indicating a state of the object, a purpose data acquiring module 202 that acquires purpose data which is a purpose of moving the drone, and a detecting module 203 that detects an action point, which is position information at which an action for the purpose is executed, based on the acquired state data and purpose data.
US10589857B2	Unmanned aerial vehicle An unmanned aerial vehicle adapted for hover and short/vertical take-off and landing (S/VTOL) is disclosed. The vehicle comprises: a body having an aspect-ratio less than two and having therein a payload volume, at least one propeller located forward of the body, at least one rudder. The body may have an inverse Zimmerman planform which provides lift as air flows across the body in horizontal flight/fixed wing mode, and further adapted such that during hover and/or short/vertical take-off and landing (S/VTOL) the vehicle operates as a rotorcraft with the body oriented with the at least one propeller substantially above the body. The vehicle is suited to a method of inspection, such as power line inspection where large distances can be analysed efficiently by flying in fixed wing mode, but by transitioning to hover mode allows detailed inspection of selected areas.
US10589855B2	Tiltrotor aircraft with outboard fixed engines In a first aspect, there is a rotor system for a tiltrotor aircraft, the rotor system including an upper outboard engine in a fixed location on a wing member of the tiltrotor aircraft; a lower outboard engine in a fixed location on the wing member; and a prop-rotor pylon in power communication with the upper and lower outboard engines, the prop-rotor pylon being configured to selectively rotate between a vertical position and a horizontal position. In another aspect, there is provided a tiltrotor aircraft including a fuselage; a wing member; an upper outboard engine in a fixed location on the wing member; a lower outboard engine in a fixed location on the wing member; and a prop-rotor pylon in power communication with the upper and lower outboard engines, the prop-rotor pylon being configured to selectively rotate between a vertical position and a horizontal position.
US10589851B2	Multicopter-assisted system and method for launching and retrieving a fixed-wing aircraft The present disclosure provides various embodiments of a multicopter-assisted launch and retrieval system generally including: (1) a multi-rotor modular multicopter attachable to (and detachable from) a fixed-wing aircraft to facilitate launch of the fixed-wing aircraft into wing-borne flight; (2) a storage and launch system usable to store the modular multicopter and to facilitate launch of the fixed-wing aircraft into wing-borne flight; and (3) an anchor system usable (along with the multicopter and a flexible capture member) to retrieve the fixed-wing aircraft from wing-borne flight.
US10589848B2	Landing-gear assembly for an aircraft, the landing-gear assembly including a secondary shimmy damper A landing-gear assembly (1) for an aircraft, the landing-gear assembly comprising: an axle shaft (2); a leg (3) presenting a first portion (3a) carrying said axle shaft (2) and a second portion (3b) connected to a carrier structure of the aircraft; a main damper (5); and a first secondary damper (6a) distinct from the main damper (5). The first secondary damper (6a) is carried by the axle shaft (2) and comprises: an inertial mass (M); and connection means (7a) between the inertial mass (M) and the axle shaft (2) damping movements of the inertial mass (M) along a first axis (X1) of movement of the inertial mass (M) relative to the axle shaft (2), said first axis of movement (X1) extending in a plane (P) perpendicular to said steering axis (Z).
US10589847B2	Lockable wheel actuator disengagement system on an aircraft landing gear A landing gear (0) for an aircraft comprising a wheel (R), a system (1) for rotationally driving the wheel that is mobile between a clutched position and a safety position by passing through a declutched position, and a manoeuvring system (3) to displace the driving system (1) between its declutched and clutched positions. The gear comprises an elastic return (4) for returning the driving system (1) to its safety position and first and second abutments (51a, 52a) that are separated as long as the driving system (1) is away from its safety position and in contact with one another when the driving system (1) is in safety position. The first and second abutments (51a, 52a) oppose the passing of the driving system (1) from its safety position to its declutched position when the abutments are in contact with one another.
US10589845B2	Autopilot system, and related components and methods A device for releasably mounting an autopilot control circuit to a flight control component of an aircraft, includes a frame that holds a component of an autopilot control circuit; a first coupler releasably fastened to the frame and operable to releasably mount the frame to the airframe of an aircraft; and a second coupler releasably fastened to the frame and operable to releasably mount the frame to a flight control component of the aircraft. When the device is releasably mounted in an aircraft's cabin and the autopilot control circuit is engaged, the autopilot control circuit controls an aspect of the aircraft's flight by moving the second coupler relative to the first coupler. With the device one can releasably mount an autopilot control circuit to an aircraft that does not have one and use the autopilot control circuit and device to control one or more aspects of the aircraft's flight.
US10589844B2	Method of controlling aerodynamic means of an aircraft, an associated control system, and an aircraft provided with such a control system A control method for controlling aerodynamic means of an aircraft having mechanically decoupled flight controls enabling the aircraft to be piloted by at least two pilots. The aircraft has at least two control members operated by respective ones of the at least two pilots and each enabling control signals to be generated for causing the aerodynamic means to move relative to an incident air stream. The control method includes piloting logic (“operational” logic). The operational logic includes a dual operating mode in which each control member can control the aerodynamic means. In the dual operating mode, only one of the at least two control members, (the “activated” member), has exclusive control over a full travel amplitude of the aerodynamic means. The other control member, (the “deactivated” member), then is temporarily inoperative on the aerodynamic means.
US10589843B2	Propulsion device A propulsion device includes a cylinder body, a first set of blades, a second set of blades, a first transmission shaft, a second transmission shaft, a power gear box and an accelerator. The first set of blades and the second set of blades are disposed in an airflow channel of the cylinder body. The first transmission shaft is connected to the first set of blades and the second transmission shaft is connected to the second set of blades. The first transmission shaft and the second transmission shaft are interconnected by the accelerator. The first set of blades has a first rotation speed, and the accelerator causes the second set of blades to have a second rotation speed. The second rotation speed is greater than the first rotation speed to increase the propulsion force.
US10589842B2	Spinners for use on tiltrotor aircraft A proprotor assembly for a tiltrotor aircraft having a forward flight mode. The proprotor assembly includes a spinner subjected to freestream airflow during forward flight. The spinner is elongated to form a tapered leading portion and a substantially cylindrical aft portion. The spinner forms a plurality of rotor blade cutouts exposing an inner chamber. The proprotor assembly includes a plurality of proprotor blade assemblies protruding radially from the spinner through the rotor blade cutouts. The rotor blade cutouts are formed at the substantially cylindrical aft portion of the spinner to reduce the freestream airflow into the inner chamber via the rotor blade cutouts during forward flight, thereby reducing drag experienced by the tiltrotor aircraft.
US10589841B2	Aircraft hub fairing with movable members In one aspect, a spinner fairing includes a base configured to be fixed relative to a hub system; a movable spinner assembly movable relative to the base; the movable spinner assembly comprising a first movable member and a second movable member. Each first and second movable member being selectively configurable between a closed position and a contracted position, in which the movable spinner assembly has a decreased shape and/or volume. In another embodiment, a spinner fairing can include at least one static member and a moveable member. In still another embodiment, a rotor head fairing assembly includes an upper housing and a lower housing coupled to a hub system; the upper housing including an upper movable member; the lower housing comprising a lower movable member. In yet another embodiment, a rotor head fairing includes at least one moveable upper housing and lower housing.
US10589834B2	Retention of an electro-optic window assembly An aircraft window includes an outer window assembly that includes a pressure pane coupled to a pressure pane frame. An inner window assembly includes a bezel adapted to couple to a perimeter of the inner window assembly against the outer window assembly. The bezel has a plurality of attachment features disposed thereon. A plurality of retaining features is disposed around the perimeter of the window. The retention features are configured to engage the attachment features for retaining the inner window assembly on the outer window assembly.
US10589833B2	Drain grommet with integrated fire shield A drain grommet with integrated fire shield. In one embodiment, the drain grommet includes a drain tube configured to extend through a drain, and to pass fluid through the drain via an opening into a hollow channel of the drain tube. The drain grommet further includes a fire shield integrally coupled with the drain tube via a standoff, wherein the standoff supports the fire shield at a vertical distance above the opening of the drain tube, and wherein the fire shield is larger than the opening of the drain tube in a horizontal plane.
US10589831B2	Multi-axis aircraft with a wind resistant unit A multi-axis aircraft with a wind resistant unit includes a fuselage having an upper face and a lower face. The fuselage includes a central axis passing through the upper face and the lower face. A plurality of rotors is mounted to the fuselage. Each rotor includes a rotating axis parallel to the central axis. A wind resistant unit includes a plurality of wind barriers disposed in a radial direction perpendicular to a reference axis. Each wind barrier includes a plurality of rods fixed by at least one fixing member. Two adjacent rods have a passage therebetween. Each rod includes an axis proximal end facing the reference axis and an axis remote end remote to the reference axis. Each wind barrier includes a coupling end and an airflow diversion end. The coupling end is fixed by at least one coupling member to the upper face of the fuselage.
US10589830B2	Marine vehicle thruster control method A method for controlling a thruster of a marine vehicle includes a body and a thruster mounted on the body of the vehicle, the vehicle being at least partially immersed in a liquid and moving with respect to the liquid along an axis of displacement in a direction of displacement and rotating about at least one axis of rotation perpendicular to the axis of displacement with a rotational speed, the thruster including an upstream propeller and a downstream propeller along the axis of displacement in the direction of displacement. The method including a stabilization step, in which the thruster is controlled such that the main axis of the upstream flow generated by the upstream propeller at a given instant t is an estimated main axis on which a position of a center of the downstream propeller, situated substantially on the axis of rotation of the downstream propeller, is estimated to be situated at a later instant t+dt at which the flow generated by the upstream propeller at the given instant t reaches the downstream propeller, the estimated main axis depending on the rotational speed of the vehicle.
US10589829B2	Gliding robotic fish navigation and propulsion A robotic submersible includes a housing having a body and a tail. In another aspect, a pump and a pump tank adjust the buoyancy of a submersible housing. In a further aspect, a first linear actuator controls the pump and/or a buoyancy, and/or a second linear actuator controls a position of a battery and/or adjusts a center of gravity. Another aspect includes a pump and at least one linear actuator that control gliding movements of the housing. In still a further aspect, a motor couples a tail with a body, such that the motor controls the movements of the tail to create a swimming movement. Moreover, an additional aspect provides a controller selectively operating the pump, first actuator, second actuator, and motor to control when swimming and gliding movements occur.
US10589827B2	Structure for stabilizing a barrel on a pontoon vessel A structure for stabilizing a barrel on a pontoon vessel includes a deck structure. First And second hull frame members are affixed to the deck structure and extend therealong. In spaced relationship to each other. A first and second conduit extends along a respective hull frame member; the first conduit being spaced from the second conduit by a distance to receive a portion of a barrel therebetween and each conduit contacting the barrel above a barrel central line. A strap having a first end anchored near the first conduit, and tracing a path from the anchor beneath, and in contact with, the barrel disposed between the first conduit in the second conduit, along the second conduit, and returning to the first conduit by tracing a path from the second conduit to the first conduit beneath and in contact with the barrel.
US10589823B1	Pontoon boat A pontoon boat includes port and starboard pontoons and cross members connecting the pontoons. A shock absorber may be installed at each point of connection of the pontoons to the cross members. A cross member may be embodied as a double-webbed beam having first and second parallel flanges and first and second webs disposed between and connected to the flanges. Each pontoon may include a two-stage lifting strake having a first surface and a second surface inclined from the first surface.
US10589815B2	Transformable Bicycle The present invention provides a transformable bicycle. The transformable bicycle including: a pair of front fork members which are connected to a front wheel, and which are arranged with the front wheel interposed therebetween; a head tube which is connected a fork support bar; a frame which is coupled to the head tube, and which is connected such that the head tube is rotatable around a bolt pin; a fastening device which is connected to the head tube; another fastening device which is installed with the fastening device and a spring interposed therebetween; a fastening device handle which allows the front fork members to be folded toward the frame in such a manner that the fastening device handle rotates the head tube connected to the fastening devices around the bolt pin by pulling the fastening devices during rotation around pins; a seat; and a rear wheel.
US10589803B2	Deployable aerodynamic bed cover system An active bed cover system having at least one deployable panel and at least one actuator. The deployable panel extends and retracts based on vehicle requirements and provides reduction in vehicle drag, thereby reducing emissions and improving fuel economy. Additionally, it allows for the system to retract within the tailgate and/or cargo bed liner allowing for access to the bed and improved usability and aesthetics. The active bed cover provides a fully deployable system with object detection, declutching of the actuator to help prevent damage, and communication with the vehicle to determine proper deployment and function.
US10589801B2	Vehicle propulsive aerodynamic elements Drag reducing systems for vehicles are provided. In one aspect, a drag reducing system generally includes an airfoil rotatably couplable to the vehicle and configured to provide a lift force to the vehicle as a result of differential airflow velocity over the upper surface with respect to the lower surface. The drag reducing system may further include a flow alignment vane to rotationally align the airfoil to the direction of airflow. In another aspect, a drag reducing system generally includes an air vane hingedly couplable to a surface of a vehicle and configured to rotate from a first stowed position to second deployed position. The air vane includes a flared leading portion to provide a force to bias the air vane toward the first position and a flared lateral portion to provide a force to rotate the air vane to the second deployed position.
US10589793B2	Pillar structure for a vehicle A pillar structure for a vehicle including: a pillar main body portion that is provided at a vehicle front portion and extends in a vehicle vertical direction, the pillar main body portion including a pair of pillar framework portions with chamber structures and a plate-shaped transparent member, the pair of pillar framework portions being disposed spaced apart in a vehicle front-and-rear direction, and the transparent member being attached to vehicle outer sides of the pair of pillar framework portions and isolating a vehicle cabin interior from a vehicle cabin exterior; and a reinforcing member provided with a pair of base portions and a transparent bridging portion, the base portions being respectively attached to vehicle inner sides of the pair of pillar framework portions and extending in the vehicle vertical direction along the pillar framework portions, and the bridging portion partially bridging between the pair of base portions.
US10589791B2	Vehicle body structure A vehicle body structure includes a first structural member, a second structural member, and a ridge portion. The first structural member has a first linear expansion coefficient and is provided with a joined portion. The second structural member has a second linear expansion coefficient exceeding the first linear expansion coefficient and is provided with a plurality of joining portions at an outer edge portion of the second structural member, and the joining portions are joined to the joined portion. The ridge portion is formed in the outer edge portion to protrude in a plane intersection direction intersecting with a joining surface of the joining portion and is continuous from one of the joining portions to another one of the joining portions.
US10589789B2	Vehicle body front part structure A vehicle body front part structure includes: a pair of right and left front side frames each extending in a vehicle front-rear direction; a pair of right and left upper members each extending in the vehicle front-rear direction at respective outer sides in a vehicle width direction of the pair of right and left front side frames; and a pair of right and left lower members each located at a vehicle front side of each of the upper members and each allowing a vehicle front side end part thereof to be coupled to each of the front side frames. In the vehicle body front part structure, each of the lower members is composed of a pipe member, and the vehicle front side end part of each of the lower members linearly extends in an up-down direction.
US10589786B2	Steering assist device A steering assist device includes a driving support ECU. The driving support ECU is configured to determine on whether or not accelerator operation is performed during execution of a lane change assist control. The driving support ECU is configured to prohibit execution of an original lane return assist control, when the driving support ECU determines that the accelerator operation has been performed.
US10589784B2	Systems and methods for intention-based steering of vehicle Systems and methods for an imaging system having a memory with a historical localization dictionary database having geo-located driving image sequences, such that each reference image is applied to a threshold to produce a binary representation. A sensor to acquire a sequence of input images of a dynamic scene. An encoder to determine, for each input image in the sequence, a histogram of each input image indicating a number of vertical edges at each bin of the input image and to threshold the histogram to produce a binary representation of the input image. A visual odometer to compare the binary representations of each input image and each reference image, by matching an input image against a reference image. Wherein the visual odometer determines a location of the input image based on a match between the input image and the reference image.
US10589783B2	Systems and methods for automatically determining an autonomous steering system center A method for performing operations onboard a vehicle is provided. The method obtains a steering calibration command, by a computing device communicatively coupled to a steering mechanism for the vehicle; initiates execution of the steering calibration command, by the computing device via the steering mechanism; determines at least one maximum steering angle of the vehicle, based on execution of the steering calibration command, the at least one maximum steering angle being associated with a maximum potential position of the steering mechanism; identifies a zero-position center of the steering mechanism, based on the at least one maximum steering angle of the vehicle; stores the zero-position center and the at least one maximum steering angle, by the computing device, for future use; and broadcasts the zero-position center and the at least one maximum steering angle, via a Controller Area Network (CAN) bus of the vehicle, by the communication device.
US10589780B2	Electric power steering apparatus [Problem]An object of the present invention is to provide an electric power steering apparatus that easily obtains equivalent steering torques to vehicle driving information such as a steering angle without being affected by a road surface state and aging-changes of mechanism characteristics of a steering system.[Means for Solving the Problem]The electric power steering apparatus that assist-controls a steering system, comprises: a target steering torque generating section to generate a target steering torque based on vehicle driving information, a converting section to convert the target steering torque into a target torsional angle, and a torsional angle control section to calculate the current command value based on the target torsional angle, a torsional angle of the torsion bar and a motor angular velocity; and the torsional angle control section comprises a torsional angle feedback compensating section to output a target torsional angular velocity corresponding to a deviation between the target torsional angle and the torsional angle, a velocity control section to output the current command value based on the target torsional angular velocity, and a stabilization compensating section to perform feedback to the current command value by setting a transfer function to at least one of angle relation information.
US10589779B2	Electric power steering apparatus An electric power steering apparatus includes: a current command value determining section that determines a current command value based on steering torque and vehicle speed; a vibration extracting filter that extracts a first vibration component having a predetermined amplitude and first predetermined frequency range depending on motor angular velocity; a vibration extracting section that extracts a second vibration component having a second predetermined frequency range depending on motor angular acceleration; a first compensation value calculating section that calculates a first vibration suppression compensation value based on the first vibration component extracted by the vibration extracting filter; and a second compensation value calculating section that calculates a second vibration suppression compensation value based on the second vibration component; and suppresses vibrations of the motor by feeding back the first vibration suppression compensation value and the second vibration suppression compensation value calculated to the current command value.
US10589778B2	Method and system for active steering for start-stop events A vehicle is provided. The vehicle may include an engine that is configured to auto-stop and auto-start. The system may also include a controller programmed to power an electrical actuator coupled to a steering mechanism to synchronize a drive angle of the vehicle and a steering wheel angle of the vehicle, in response to a parameter indicative of a likelihood of a wheel slip event exceeding a threshold and the steering-wheel angle being greater than a predetermined threshold.
US10589776B2	Use of a stepped shrink-fit ring to assemble a steering assist motor in a steering case An assembly method in which an assembly ring is force-fitted between a first part and a second part such as to create: a tightening contact between the first part and the inner face of the ring, by means of plastic deformation of the ring, said tightening contact occupying a first interference zone; and a tightening contact between the second part and the outer face of the ring, said tightening contact occupying a second interference zone. The assembly ring comprises a first ring segment (T1) and a second ring segment (T2) which are stepped axially in relation to one another and which have different radial dimensions from one another, such as to confine the first interference zone to the first ring segment (T1) and the second interference zone to the second ring segment (T2), in order to prevent the first interference zone and the second interference zone from overlapping axially.
US10589775B2	Feedback actuator for a steering mechanism A feedback actuator for a steering mechanism for motor vehicles may include a steering adjuster that acts on the steered wheels and is controlled electronically based on steering commands of a drive of the motor vehicle. The feedback actuator may transmit feedback from a road to a steering wheel via a steering shaft. Further, the feedback actuator may have a preloaded belt drive and an electric motor configured as torque-generating means. The feedback actuator may generate a torque to simulate the feedback of the road. The torque may be formed by a sum of a torque from the preloaded belt drive applied to the steering shaft and a torque from the electric motor applied to the steering shaft.
US10589773B2	Dashboard gasket for coupling a power steering device to the dashboard of a vehicle A vehicle fitted with a steering device including a steering mechanism protected by a steering casing, the steering casing itself being housed in an engine compartment that is separated from the interior of the vehicle by a dashboard, the steering device also including a steering wheel, located in the interior, and to which the steering mechanism is connected by a steering column that extends out of the steering casing and passes through the dashboard, the vehicle including, in order to provide a seal around the steering column, between the steering casing and the dashboard, an elastomeric coupling gasket including, in a single piece, a central first sealing ring that surrounds and clamps around the steering column and a peripheral second sealing ring that is inserted between the steering casing and the dashboard, at a distance from and around the first sealing ring.
US10589771B2	Cart with wheel that is easily lockable and unlockable A cart has a wheel that is easily lockable and unlockable while being securely braked. The cart includes a platform having a wheel and on which freight is loaded, a handle bar including an inverted U shaped frame including a left frame, a right frame, and a connecting frame, a wheel locking and unlocking operation part provided on the inverted U shaped frame and configured to be pressed and elastically restored, and an operation part configured to operate by an operation of the wheel locking and unlocking operation part, and a folding operation part including a pedal provided at one end of the platform, a pedal connecting part connected to the pedal from a lower surface of the platform, and a folding operation rod supported by the pedal connecting part and configured to vertically move.
US10589768B2	Adjustable storage devices, systems and associated methods Devices, systems, and methods for the storage of objects are provided, such as an adjustable storage device for protecting fragile decorative items, which can include a plurality of adjustable rectangular storage compartments arranged in a rectangular array, a first plurality of elongate structures spaced at intervals and oriented parallel to one another, a second plurality of elongate structures spaced at intervals and oriented parallel to one another, wherein the first plurality of elongate structures is oriented perpendicularly to the second plurality of elongate structures to form an opening for each to of the plurality of storage compartments, and a flexible liner disposed across the plurality of storage compartments, wherein the flexible liner extends through each single opening to form sides and a bottom of each storage compartment.
US10589766B2	Railroad crossing gate monitoring and alarm system Aspects of the disclosed embodiments generally relate to a current monitoring and alarm system for a railroad crossing gate. The system is capable of determining that the gate is functioning properly or not. In addition, the system can issue an alarm or provide some other indicator when the gate is not functioning properly or is being subjected to excessive loading.
US10589763B2	Method and measuring system for registering a fixed point adjacent a track A method of determining the actual position of a track relative to a fixed point located in a lateral vicinity of the track by using a registering device being mobile on the track includes surveying the position of the fixed point relative to the track. The registering device is moved along the track, image pairs of the lateral vicinity of the track are continuously recorded by a stereo camera system on the registering device and the fixed point is searched for in the image pairs by pattern recognition carried out in an evaluation device. Upon recognition of the fixed point, the position of the fixed point relative to the track is determined by evaluating at least one image pair. This creates the possibility of surveying fixed points in passing with the configuration of the fixed point not being bound to any special form. A measuring system is also provided.
US10589762B2	Transverse rail switching element In at least one embodiment the present invention provides a transverse rail switching element for switching a rail vehicle from a first position to a transversely removed second position in a thrilling manner, having an entry track section, a vehicle shuttle adapted to receive a rail vehicle from the entry track section at the first position, a transverse track section extending from the first position to the transversely removed second position, at least one exit track section, primary propulsion means adapted to translate the rail vehicle from the vehicle shuttle to the at least one exit track section when the vehicle shuttle is in the transversely removed second position.
US10589761B2	Rail vehicle in particular a locomotive A rail vehicle, in particular a locomotive, includes a chassis, a central buffer coupling, a coupling shaft which is hinged to the chassis and carries a coupling head, and a coupling support which has a spring-mounted transverse beam for supporting the coupling shaft. The coupling support has two retaining sheets which are secured to the chassis, and the transverse beam has two guide grooves which run in the spring direction. Each of the retaining sheets engages into a respective one of the guide grooves in a form-locking manner such that the transverse beam is guided in a movable manner in the spring direction and transversely thereto, and each retaining sheet has a predetermined breaking point. In this way, the coupling support is secured to the chassis in a simple manner.
US10589759B2	Railway car truck friction shoe A friction shoe includes a bottom base engaging and supported by a pair of support springs, and a sloped wall engaging the sloped support face of a bolster. The bottom base includes a cylindrical spring lug that has a center opening that extends through the spring lug. The bottom surface of the spring lug is flat and smooth and is configured to engage an additional concentrically nested support spring. The additional spring increases the force between the vertical support face of the wedge and the vertical wear plate of the side frame.
US10589758B2	Plug door opening-closing device A plug door opening-closing apparatus, which is adapted for use with a vehicle having a vehicle front-rear direction and a vehicle width direction, includes a door hanger capable of coupling to a door panel of the vehicle, a movable guide configured to guide movement of the door hanger in the front-rear direction and move in the width direction, a guide support member that guides movement of the movable guide in the width direction, and an interlock mechanism mechanically connected to the movable guide. The interlock mechanism is configured to conform a movement amount of a first portion of the movable guide in the vehicle width direction to a movement amount of a second portion of the movable guide in the vehicle width direction.
US10589757B2	Coil railcar with floating floor sheet A transverse trough coil car includes a plurality of transverse troughs, a pair of trucks, a center sill supported on the trucks, a pair of side walls extending the length of the car coupled to the center sill, and a plurality of trough forming assemblies with each trough forming assembly including at least one floating floor sheet. Each one floating floor sheet is structured to allow for thermal expansion in a first direction along a longitudinal axis of the car body and in a second direction transverse to the longitudinal axis of the car body.
US10589753B2	Vehicle warning system for hearing-impaired person and control method thereof A warning system for a hearing-impaired person of a vehicle includes: a sound sensing unit disposed at a vehicle to sense sound outside of the vehicle; a database storing characteristic information of a plurality of specific sounds and visual information corresponding to the characteristic information of the plurality of specific sounds; an output unit outputting visual information corresponding to the plurality of specific sounds; and a controller extracting characteristic information of the sound sensed by the sound sensing units. In particular, the controller determines a type of the sensed sound by comparing the extracted characteristic information of the sensed sound with the characteristic information of the plurality of specific sounds stored in the database, and outputs visual information corresponding to the determined type of the sensed sound through the output unit.
US10589752B2	Display system, display method, and storage medium A display system includes: a first display unit (400) that displays an image indicating a driving assist state of a vehicle which includes an automated driving state; a second display unit (400) that displays an image that resembles a road on which the vehicle travels; and a display control unit (120) that allows the second display unit to display approximately the entire region of a region corresponding to a recommended lane applied to a control unit that performs the automated driving in a predetermined color, and allows a target trajectory generated by the control unit that performs the automated driving to be displayed in a region narrower than the recommended lane.
US10589749B2	Method and system for early detection of vehicle parts failure System and method for early detection of vehicle parts failure are disclosed. The method includes identifying discriminative rules from unstructured and structured data corresponding to subsystems of a vehicle. Causal parts categories are mapped to the subsystems based on the discriminative rules to obtain a plurality of causal part-subsystem pairs. The causal part categories are representative of vehicle parts responsible for failure of corresponding subsystems. Scores are assigned to the causal part-subsystem pairs based on an occurrence of causal part categories to a corresponding subsystem within a source. An emerging issue score is computed based on the scores, a corresponding weightage associated with the sources of the causal part category, and an extent of coverage of the each causal part in each of the plurality of causal part-subsystem pairs. The emerging issue score is compared with the threshold vehicle part failure score to identify causal part categories associated with vehicle parts failure.
US10589736B2	Front end motor-generator system and hybrid electric vehicle operating method A system and method are provided for hybrid electric internal combustion engine applications in which a motor-generator, a narrow switchable coupling and a torque transfer unit therebetween are arranged and positioned in the constrained environment at the front of an engine in applications such as commercial vehicles, off-road vehicles and stationary engine installations. The motor-generator is preferably positioned laterally offset from the switchable coupling, which is co-axially-arranged with the front end of the engine crankshaft. The switchable coupling is an integrated unit in which a crankshaft vibration damper, an engine accessory drive pulley and a disengageable clutch overlap such that the axial depth of the clutch-pulley-damper unit is nearly the same as a conventional belt drive pulley and engine damper. The front end motor-generator system includes an electrical energy store that receives electrical energy generated by the motor-generator when the coupling is engaged. When the coupling is disengaged, the motor-generator may drive the pulley portion of the clutch-pulley-damper to drive the engine accessories using energy returned from the energy store, independent of the engine crankshaft.
US10589735B2	Front end motor-generator system and hybrid electric vehicle operating method A system and method are provided for hybrid electric internal combustion engine applications in which a motor-generator, a narrow switchable coupling and a torque transfer unit therebetween are arranged and positioned in the constrained environment at the front of an engine in applications such as commercial vehicles, off-road vehicles and stationary engine installations. The motor-generator is preferably positioned laterally offset from the switchable coupling, which is co-axially-arranged with the front end of the engine crankshaft. The switchable coupling is an integrated unit in which a crankshaft vibration damper, an engine accessory drive pulley and a disengageable clutch overlap such that the axial depth of the clutch-pulley-damper unit is nearly the same as a conventional belt drive pulley and engine damper. The front end motor-generator system includes an electrical energy store that receives electrical energy generated by the motor-generator when the coupling is engaged. When the coupling is disengaged, the motor-generator may drive the pulley portion of the clutch-pulley-damper to drive the engine accessories using energy returned from the energy store, independent of the engine crankshaft.
US10589730B2	Hydraulic unit of a vehicle brake system having an eccentric chamber A hydraulic unit of a vehicle brake system includes at least one pump element that is driven via an eccentric, which is enclosed by an eccentric chamber. The hydraulic unit also includes a vacuum pump that is configured to maintain a vacuum in the eccentric chamber while the hydraulic unit is in operation.
US10589729B2	Pressure-limiting valve A pressure-limiting valve has a valve housing, a piston, a pressure-limiting adjustment spring, at least one inlet and at least one outlet. The piston can assume an open position in which the inlet and the outlet are connected to each other and a closed position which separates the inlet and outlet. A first piston ring has a sealing surface and has a small pneumatic active surface relative to a second piston ring. Between the first and second piston rings the piston has a substantially truncated cone-like portion which tapers toward the first piston ring. In the closed position, the sealing surface of the first piston ring is sealingly drawn against a housing collar by a pneumatic force acting counter to the force of the pressure-limiting adjustment spring. A pneumatic passage for creating a safety valve function closable by a spring-loaded safety valve body is provided in the piston.
US10589725B2	Window-wiper spray nozzle for a vehicle The invention relates to a window-wiper spray nozzle (350) for a vehicle, especially a motor vehicle, comprising first detachable mounting means designed to cooperate with second mounting means of a support (390) for mounting said spray nozzle, the spray nozzle comprising at least one actuating means (370), such as a push-button, independent from said mounting means and designed to release the spray nozzle from the mounting support and thereby allow the spray nozzle to be dismounted from the mounting support.
US10589723B1	Imaging system A sensor having a positive temperature coefficient shroud is described, as well as a computing system to control actuation of the positive temperature coefficient shroud. According to one example, the computing system executes a method that actuates the positive temperature coefficient shroud of the sensor based on a transmittance parameter of the sensor.
US10589722B2	Server device, car sharing system, information processing method, and recording medium A server device for a car sharing system includes an image request device, a use permission request device, and an authentication information issue device. The image request device is configured to transmit an image request signal to the user terminal when a use request signal for the vehicle is received. The image request signal requires transmission of a user face image. The use permission request device is configured to transmit a use permission request signal including the user face image transmitted from the user terminal to the owner terminal. The authentication information issue device is configured to transmit predetermined authentication information to the user terminal when a use permission signal transmitted from the owner terminal in response to the use permission request signal is received. The predetermined authentication information is information for enabling an operation of the vehicle.
US10589716B2	Vehicle function control system using sensing and icon display module A vehicle function control system includes a sensing and projecting module disposed at an exterior portion of the vehicle and having an illumination source operable to project a plurality of icons onto a ground area at or near the vehicle or an exterior surface of the vehicle, with each of the projected icons being representative of a respective vehicle function. The module includes a sensing device operable to sense the presence of a user at or near one of the projected icons and, responsive to the sensing of the presence of the user, the system determines which of the projected icons is being selected by the user. A control is responsive to an output of the sensing device and, responsive to determination of the user at or near a selected particular projected icon, the control controls a function of the vehicle associated with the selected particular projected icon.
US10589713B2	Determining an occupancy status of a vehicle seat A computer that may be programmed to: in response to receiving an indication that a vehicle is approaching a geofence boundary, retract slack in a webbing associated with a seat in the vehicle by actuating a seatbelt retractor; then receive measurement data from one or more sensors associated with the seat; using the data, determine whether an occupant occupies the seat; and when no occupant occupies the seat, then transmit an instruction to stop the vehicle.
US10589712B2	Vehicle seat harness retainer A harness retainer having a cover, a magnet, a rear plate and a fastener. The cover has a ledge defining a flat surface. The rear plate is attached to the cover and is constructed to define a contour having a radius of curvature. The magnet is disposed between the cover and the rear plate and is disposed under the ledge. The rear plate has a first retainer and a second retainer. The fastener is fixedly attached to the first retainer and removably attached to the second retainer.
US10589708B2	Vehicle airbag system An assembly includes a seat. The assembly includes a housing. The assembly includes an airbag inflatable to an inflated position having a first inflatable leg and a second inflatable leg extending from the housing, and an inflatable member extending from the first inflatable leg to the second inflatable leg. The assembly includes a tether having a first end fixed to the first inflatable leg and a second end spaced from the first end and the airbag.
US10589707B2	Airbag apparatus An airbag apparatus includes an airbag and an inflator. The airbag is configured to be deployed and inflated by the inflation gas at a position forward of a vehicle seat. The airbag includes a main bag member, an auxiliary bag member, and a tether. The main bag member is configured to be attached to a base member located at a position forward of the vehicle seat in the vehicle. The inflation gas is supplied from the inflator to the main bag member. The auxiliary bag member has a smaller volume than the main bag member and projects rearward from the main bag member. The tether extends across a boundary portion between the main bag member and the auxiliary bag member. A communicating portion, which allows communication between the main bag member and the auxiliary bag member, is provided around the tether in the boundary portion.
US10589705B2	Restraint system A restraint system includes an instrument panel having an exterior panel directed downward, an airbag having an uninflated position behind the exterior panel and having a left chamber and a right chamber, a left inflator coupled to the left chamber, a right inflator coupled to the right chamber, and a controller programmed to selectively activate each inflator to one of a high output and a low output based on an impact angle.
US10589701B2	Circuit body for vehicle A circuit body for a vehicle includes: a plurality of control boxes dispersedly arranged on the circuit body; a trunk harness connecting one of the control boxes to another of the control boxes; and a branch harness connecting the control boxes to the electric component. The control boxes, the trunk harness and the branch harness are configured to ground a power circuit and a signal circuit through grounding routes different from each other. The power circuit supplies the electric power from a power source to the electric component through the control boxes. The signal circuit transmits a communication signal between the control boxes and the electric component and between one of the control boxes and another of the control boxes.
US10589691B2	Ladder rack and cable cleat system A cable cleat system that secures cables to a ladder rack. The cable cleat system includes a mounting bracket assembly with a bracket body and a floating support bracket slidably mounted to the bracket body. A metal locking tie is positioned between the floating support bracket and the mounting bracket assembly. The mounting bracket assembly is secured to a ladder rung of the ladder rack and the floating support bracket supports the cables secured to the ladder rack. The metal locking tie wraps around the cables supported by the floating support bracket. The floating support bracket and the metal locking tie slide along the bracket body for enabling thermal expansion and contraction of the cables secured to the ladder rack.
US10589689B2	Interior member An interior member for attachment to a car body configuring member includes a fixing tool to fix the interior member to the car body configuring member, a base portion with a through-hole which allows the fixing tool to pass therethrough, and a movement restricting portion that protrudes from an outer surface of the base portion. The fixing tool has a head disposed on the outer surface, and a shaft extending from the head and fixed to the car body configuring member through the through-hole. The interior member is displaceable in a direction along the outer surface of the base portion within a predetermined area in a state where part of the car body configuring member or the fixing tool is inserted. The movement restricting portion has an abutting portion which restricts movement of the head in the direction along the outer surface.
US10589685B1	Portable expandable mirrors with lights for use in motor vehicles and elsewhere Billions of people around the world use a mirror more than once a day. Millions of people own a motor vehicle. The last place we find ourselves prior to many events is in our car. Such events include going on a date, touching up makeup, an important job interview, and other instances where we need to look our best. It is crucial to provide a superior light and mirror experience for facial viewing in these situations. I have created a revolutionary product to help millions around the world succeed by helping them see themselves in better light. More broadly, I have provided solutions, involving combinations of mirrors, light elements, and display screens, for providing users with superior mirror-related experiences in various vanity, medical, travel, and entertainment situations.
US10589682B2	View angle adjustment mechanism in view device This invention relates to a view angle adjustment mechanism that causes a view element tilting section holding a view element to be supported by a tilting support section via a forcible fitting-type pivot to perform view angle adjustment. A pivot is assembled by forcible fitting between a pivot convex and a pivot concave. The pivot convex includes a spherical surface. The pivot concave includes a surface formed by arranging two conical surfaces so as to face in respective directions opposite to each other along a center axis X of the pivot concave. The spherical surface of the pivot convex is inscribed in the two conical surfaces of the pivot concave.
US10589681B2	Outer mirror for vehicle An outer mirror for a vehicle according to the technology of the present disclosure includes a mirror stay, a mirror visor, and a mirror for checking behind the vehicle. The mirror stay is provided at a vehicle body side face. The mirror visor is supported by the mirror stay and includes an opening portion at a vehicle rear side. The mirror is provided in the opening portion. In a horizontal section cut through the mirror visor, a distance between a vehicle width direction inner side face of the mirror visor and the vehicle body side face decreases toward the vehicle rear from a front end portion of the mirror visor.
US10589677B1	System and method to exhibit information after a pedestrian crash incident One general aspect includes a method to display information after a pedestrian crash incident, the method including: receiving, at a controller, an indication of a pedestrian crash incident; in response to the pedestrian crash incident indication, via the controller, deploying a pedestrian protection apparatus to raise a portion of a hood of a vehicle; in response to the pedestrian crash incident indication, via the controller, activating one or more sensors to capture one or more images of at least a portion of a vehicle environment; adapting the captured image, via the controller, to be exhibited on a display; and exhibiting the captured images, via the controller, on the display.
US10589676B2	Vehicle display system with user input display A display system for a vehicle includes an interior camera disposed in an interior cabin of a vehicle and having a field of view interior of the vehicle that encompasses an area at or near a user input for an accessory, with the user input being accessible by a driver of the vehicle when the driver is normally operating the vehicle. A display device is viewable by the driver when the driver is normally operating the vehicle. The display device is operable to display images derived from image data captured by said interior camera. The display device displays images depicting the driver's hand as the driver's hand approaches the user input for the accessory for actuating the user input to adjust or control the accessory.
US10589671B1	3D printed air bladder mesh elastomer material A three-dimensional printed vehicle component including an integral lattice and one or more fluid chambers including an aperture for accessing an interior of the chamber. The chamber can be expanded and contracted by delivering a fluid via the aperture to and from the interior of the chamber. The vehicle component can include top and bottom sheets sandwiching the lattice and chambers. The top and bottom sheets can be integrally printed with the lattice and chambers, or can be attached thereto with an adhesive. The duration, number, frequency, and intensity of such delivery can be controlled to provide various haptic sensations to a vehicle occupant. The haptic sensation can include a massage, an indication, or a firmness of touch.
US10589669B2	Following vehicle detection and alarm device A following vehicle detection and alarm device comprises a tail camera for shooting an area behind a vehicle of interest at a predetermined frame rate, a frame quantity count unit for counting the number of frames after a following vehicle is shot in a shooting range of the tail camera until the following vehicle reaches a first position behind the vehicle of interest, an alarm instruction output unit for outputting an alarm instruction of notifying the driver of the vehicle of interest that the other vehicle is approaching at a timing set based on the number of frames counted by the frame quantity count unit, and an alarm processing unit for performing a predetermined alarm operation on the driver when the alarm instruction is output by the alarm instruction output unit.
US10589666B2	Open roof construction for a vehicle An open roof construction for a vehicle includes at least one cover capable of closing an opening in a fixed roof of the vehicle. The at least one cover comprises a light emitting layer capable of guiding light from a longitudinal edge of the light emitting layer, substantially parallel to a longitudinal direction of the vehicle, towards a main surface and capable of emitting light from a main surface of the light emitting layer towards an interior space of the vehicle. The cover further comprises a light device for emitting light into the light emitting layer, the light device including at least one light source and a light guide for guiding the light from the light source to the edge of the light emitting layer, wherein in the light guide is formed by a bundle of light fibers existing of several light fibers.
US10589664B2	System and method for automatically activating turn indicators in a vehicle Disclosed are systems and methods for activating turn indicators of a motor vehicle. The disclosed methods includes collecting, for a predetermined period of time, from a plurality of internal and externals sensors of the vehicle, information associated with a plurality of driving maneuvers performed by a driver of the vehicle, the collected information includes at least one of information about driver's behavior, vehicle condition, road condition or traffic condition; feeding the collected information into a neural network for training a plurality of rules that determine when to automatically activate turn indicators based at least on driver's behavior; applying one or more trained rules to predict the next vehicle maneuver by the driver; and automatically activating a turn indicator of the vehicle based on the application of the one or more rules before the next vehicle maneuver is performed by the driver.
US10589662B2	Adjusting system for a vehicle lighting apparatus, and method for operating such an adjusting system An adjusting system for a lighting apparatus for vehicles is configured to emit light for forming a light distribution described by a parameter set. The adjusting system includes a light control unit and is configured to modify the light distribution. The parameter set describing the light distribution is stored in the light control unit, which and configured to control the lighting apparatus such that the lighting apparatus emits light for forming the light distribution in accordance with the parameter set into an area in front of the lighting apparatus. An operator control unit separate from both the lighting apparatus and the light control unit is configured to accept user inputs and to transmit the user inputs to the light control unit, which is configured to modify the parameter set in accordance with the user inputs to produce a further parameter set describing a further user-defined, preferably dynamic, light distribution.
US10589657B1	Magnetic fastener for cargo retention An apparatus, system, and method of using the apparatus and system may generally include a strap or retention device. A first end of a fastener is operatively coupled to the strap that is configured to retain a cargo contactingly adjacent a cargo support surface. A second end of the fastener is operatively coupled to the first end. The second end has a double rod formation. A magnet may be supported in a housing in the second end. The magnet may be held in position within a recess feature of the housing. A support structure may be disposed between the double rod formation to provide additional strength and stability. The support structure may be made of metal, polymer, or other suitable material. The magnet that is configured to support the second end adjacent a side of the cargo support surface, wherein the side does not produce its own magnetic field.
US10589656B2	Systems and methods for distributing merchandise and merchandise kits at emergency locations There is provided systems and methods involving a portable distribution center for distributing merchandise in response to emergencies. The distribution center includes a transport vehicle with a locomotion system for movement of the transport vehicle to an emergency location. It also includes a conveyor system for sortation and distribution of merchandise items upon arrival at the emergency location. The conveyor system includes merchandise identifier for reading identification data from merchandise item; a plurality of sortation units for moving merchandise items to uniquely identified destination lanes; and a control circuit configured to: assign merchandise items to uniquely identified sortation destination lanes; receive identification data; and communicate with the plurality of sortation units. The distribution center also includes a power supply for energizing the conveyor system and a communication system. At the emergency location, the control circuit separates the merchandise items into predetermined kits that are sorted to the destination lanes.
US10589653B2	Utility vehicle A utility vehicle includes a passenger grip including a handle grip having an arm part extending from a dashboard toward the passenger seat, and a grip part at the arm part and gripped by the crew seated on the passenger seat, a holder outserted to the arm part of the handle grip and holding the arm part movably forward and backward in an extending direction of the arm part, and a single-action lock mechanism at the holder and fixing the handle grip to the holder. The single-action lock mechanism includes a lock pin having a distal end penetrating a through hole at the holder and engaged with an engagement hole at the arm part, a spring biasing the lock pin toward the arm part, a housing fixed to the holder and accommodating the lock pin and the spring, and a knob outside the housing and connected to the lock pin.
US10589651B2	Headrest A headrest includes: a main frame, left and right side frames, and left and right rotation-coupling portions. The main frame is supported at an upper end portion of a seatback. The left and right side frames that are disposed on left and right sides of the main frame. The left and right rotation-coupling portions couple the left and right side frames to the main frame such that the left and right side frames are capable of rotating with respect to the main frame about left and right up-down-extending axes. Each rotation-coupling portion includes a boss hole, a boss, a hinge hole, and a hinge.
US10589646B2	Vehicle seat configured to restrain lower limbs A vehicle seat includes: a power tilt mechanism; a seat front panel that forms a part of a front portion of a seat cushion, bridges a right and left pair of side frames of the seat cushion, and is configured to be rotatable by the power tilt mechanism about a tilt central axis that is provided in linking portions, at which the seat front panel is linked to the side frames, an axial direction of the tilt central axis coinciding with a seat width direction; and a control device that is connected to the power tilt mechanism, the control device being configured to activate the power tilt mechanism to cause the seat front panel to rotate in a seat upward direction, in a case in which a vehicle impact in which an occupant sitting on the seat cushion will move in a seat forward direction has been predicted.
US10589640B2	Power supply unit and vehicle seat A power supply unit including a slide rail that has an opening at an upper side a slider that slides along the slide rail, a first connector that is fixed to one end portion of the slide rail, a second connector that is fixed to the slider, and a flexible cable that is housed inside the slide rail, that has one end connected to the first connector, and that has another end folded back and connected to the second connector.
US10589638B2	Electric vehicle charging device and method for charging electric vehicle An electric vehicle charging device includes a processing unit having a memory with a routine stored therein which, when executed by the processing unit causes the processing unit to control circuitry to prevent the electric vehicle charging device from charging an electric vehicle for a random delay period and to allow the electric vehicle charging device to charge the electric vehicle starting when the random delay period ends, wherein the random delay period starts at a predetermined start time and lasts a random delay length of time. The random delay reduces the peak load on a transformer that the electric vehicle charging device and other electric vehicle charging devices receive power from.
US10589630B2	Electrified vehicle drivetrain monitoring system A control system for a vehicle includes a controller. The controller is configured to open traction battery contactors based on a potential between high-voltage cables and a chassis continuously exceeding an amplitude threshold for at least a predefined duration of time. The controller is further configured to selectively open the contactors based on data derived from the potential for periods that are each defined by the potential exceeding and then falling below the amplitude threshold without exceeding the predefined duration of time.
US10589619B2	Angled torque transmission system and method A torque transmission system (20) for transmitting torque from a prime mover (22) along a drivetrain includes a clutch device (28) configured to accept a torque input from the prime mover, an intermediate pulley (32), a belt (30) operatively engaged between the clutch device and the intermediate pulley, an angle gearbox (36) configured to change a spatial orientation of torque transmitted between an input and an output of the angle gearbox, a driveshaft (34) operably engaged between the intermediate pulley and the angle gearbox, and an output device (38) configured to accept a torque output from the angle gearbox. The clutch device is located upstream from the intermediate pulley and the angle gearbox along the drivetrain.
US10589617B2	Wheel unit A wheel unit includes a motor, a pinion gear fixed to a rotating portion of the motor, a wheel including an annular ground surface and rotating around a final gear support shaft, and a final gear disposed on one side in an axial direction with respect to the wheel. The wheel unit further includes a speed reduction mechanism which decelerates rotation of the pinion gear and transmits the rotation to the final gear and a gear case which accommodates the pinion gear. When viewed from the axial direction, the final gear support shaft and the motor shaft are disposed in different positions. The motor includes a stationary portion and a rotary portion, and the stationary portion is fixed to the gear case by an attachment plate.
US10589615B2	Decoupler for a hydraulic engine mount Methods and systems are provided for reducing NVH resultant from collisions between internal components of a hydraulic engine mount. In one example, a hydraulic engine mount may include a de-coupler with a number cavities encased therein and extending along a common circumference of the de-coupler.
US10589614B2	Reinforcement structure A reinforcement structure for protection of a vehicle power source, e.g. a battery pack or a fuel cell. The reinforcement structure extends in a first, a second and a third direction (D1, D2, D3) being perpendicular to each other, wherein an extension of the reinforcement structure is at least 5 times larger in the first and second directions than in the third direction. The reinforcement structure has a tapered shape as seen in a plane spanned by the first and second directions. The present disclosure also relates to a reinforcement unit, a vehicle power source arrangement and a vehicle utilizing such reinforcement structure.
US10589612B2	Attachment structure for vehicle exterior panel A weather strip 5 is attached to a peripheral edge of an opening 4a of a vehicle body 1′, and a deck cover 18 includes a resin outer panel 21 and an inner panel 23 joined onto a rear side of the outer panel 21. A spacer 35 is interposed between the outer panel 21 and the inner panel 23 such that a portion of the deck cover 18 provided with the spacer 35 makes contact with the weather strip 5 when the deck cover 18 is closed.
US10589608B2	Vehicle retractable roof If a roof member 12 of a vehicle retractable roof 11 is made of aluminum, a roof side stopper 65 is fixed to a reinforcing plate 50 together with a roof bracket 55, a contact surface 65 coming into contact with a vehicle side stopper 60 is disposed at a position except for a sealing surface 67 provided on the roof member 12. Then, the deformation of the roof member 12 can be reduced, the interference with the sealing surface can be avoided, and the weight of the roof side stopper 65 can be reduced.
US10589599B2	Air conditioner for vehicle To provide an air conditioner for a vehicle having a simple configuration and capable of controlling temperature in a wide range. In a dehumidification heating operation in which a refrigerant is circulated through a first heat exchanger, a second heat exchanger, an evaporator and a compressor in the order named so as to radiate the heat of the refrigerant into the first heat exchanger, there is provided a refrigerant heating means which heats the refrigerant when an outside air temperature is not higher than a predetermined temperature and when an opening degree of the second expansion valve which expands the refrigerant flowing out from the second heat exchanger is larger than an opening degree of the first expansion valve which expands the refrigerant flowing out from the first heat exchanger.
US10589594B2	Heat distribution in a motor vehicle A device for heat distribution in a hybrid motor vehicle includes an engine cooling circuit and a refrigerant circuit for a combined operation in a refrigeration heat pump mode and a reheating mode. The refrigerant circuit includes an evaporator, a compressor, a heat exchanger to supply heat from the refrigerant to air being conditioned for a passenger compartment, and a heat exchanger to transfer heat between a refrigerant of the refrigerant circuit and coolant of the engine cooling circuit. The heat exchanger operates as an evaporator for the heat transfer from the coolant to the evaporating refrigerant, and alternatively operates as a condenser for the heat transfer from the condensing refrigerant to the coolant.
US10589592B2	Air conditioning device for vehicles An air conditioning device for vehicles including an evaporator for cooling air; a heater core for heating air; and a unit case having formed therein a cooling space for accommodating the evaporator, a heating space for accommodating the heater core, and an air mixing space connected to the cooling space and the heating space. A pair of foot flow passages is in communication with the unit case, the pair of foot flow passages extending from the air mixing space and being arranged at a distance from each other in the width direction of the vehicle so as to sandwich a rear face flow passage in the width direction. The rear face flow passage and at least a part of each of the foot flow passages overlap each other when viewed in the width direction.
US10589591B2	Active damper system actuator arrangement A damper system for a vehicle is provided that includes a damper and actuator. The damper extends longitudinally along a damper axis between first and second damper ends. The actuator is separate and spaced apart from the damper. The actuator extends longitudinally along an actuator axis between first and second actuator ends. The damper and the actuator are arranged next to one another where the actuator axis is spaced from and substantially parallel to the damper axis. The damper and the actuator are positioned within a cylindrical packaging envelope that has a diameter of 300 millimeters or less. The cylindrical packaging envelope is an imaginary cylinder, which may be defined by one or more components of a vehicle's suspension system such as a coil spring or an upper suspension arm. The damper and the actuator are completely contained within the cylindrical packaging envelope.
US10589590B2	Stabilizer for vehicle A stabilizer includes a stabilizer main body, and eyes formed on both ends of the stabilizer main body. Through-holes are formed in fastening surfaces of the eyes, respectively. The stabilizer main body is covered with a main body coating film. The eye is covered with an eye coating film whose thickness is less than a thickness of the main body coating film. An inner surface of the through-hole is covered with an inner surface coating film. An incomplete coating portion is formed at a part of the inner surface of the through-hole in a circumferential direction. The incomplete coating portion is located on an extension of a straight line connecting a center of the through-hole and the center of gravity of the stabilizer main body in a side view of the stabilizer main body.
US10589582B2	Pivotal tow bar assembly A tow bar assembly for use in connecting a towing vehicle to a towed vehicle. The tow bar assembly includes a drawbar and a housing assembly capable of being configured with a supplemental braking system. A connector secures the housing to a tow hitch member, such that two separate, non-planar perpendicular axes of pivotal rotation are created. The tow hitch assembly includes at least one arm with an inner and outer portion, wherein the inner portion rotates about a central axis relative to the inner portion within the outer portion. A fourth pivotal axis is created by a connection of mounting brackets to the tow hitch member.
US10589577B2	Heavy-duty pneumatic tire A heavy-duty pneumatic tire includes a carcass ply including a main portion extending between bead cores and a pair of turn-up portions, a first reinforcing layer of a steel cord disposed in each bead portion in a U-shaped manner, and a second reinforcing layer of an organic fiber cord disposed in each bead portion and at least a part of the second reinforcing layer extending in a radial direction of the tire at an axially outward location of the first reinforcing layer. The second reinforcing layer includes an axially inner second ply and an outer second ply. The outer second ply has an inner end positioned below the bead core. The inner second ply has an inner end located axially inward of the inner end of the outer second ply, and has a substantially same length as the outer second ply in a tire cross-section.
US10589575B2	Tire A tire 1 comprises a tread portion 2, a tread edge Te provided in the tread portion 2, a shoulder main groove 3 extending continuously in the tire circumferential direction in the tread portion 2, and a shoulder land region 5 being defined between the tread edge Te and the shoulder main groove 3. The shoulder land region 5 is provided with a shoulder lateral groove 10 connecting between the shoulder main groove 3 and the tread edge Te and a first shoulder lug groove 11 extending axially inwardly from the tread edge Te and terminating within the shoulder land region 5. An angle θ1 of the shoulder lateral groove 10 with respect to the tire axial direction is larger by 10 to 40 degrees than an angle θ2 of the first shoulder lug groove 11 with respect to the tire axial direction.
US10589568B2	Wheel hub arrangement for a motor vehicle A wheel hub arrangement for a motor vehicle, provided with a hub which is rotatably mounted by a wheel bearing for the attachment of a wheel. A shaft, which is formed separately from the wheel hub, is non-rotatably coupled to the wheel hub. At the same time a first receiving section of a sealing receptacle is formed in the wheel hub in which is arranged a shaft, in which a sealing device is arranged which engages a second receiving section of the sealing receptacle formed in the axial direction with respect to an axis of rotation of the wheel hub, adjacent to the first receiving section.
US10589564B2	Capacitive touch screen compatible stylus adaptor for writing instruments An adaptor allows a user to turn any pencil or pen into a capacitive stylus while still allowing it to write on paper. When attached to a pencil, pen or similarly shaped and purposed tool, it gives the tool the added capability of operating electronic devices having a capacitive touch screen. It does this while constantly maintaining the writing instrument's intrinsic capability of marking paper. The main component of the invention comprises a fastener which allows electricity to pass along it while simultaneously allowing the writing utensil tip to be permanently exposed. It can transfer electricity from the user's hand to the touch screen without interfering with the original function or ergonomic shape of the writing instrument. A seamless workflow between surfaces is created since the same end of the writing instrument is used and no other action is required to reveal or conceal its tip.
US10589562B2	Position pointer Various embodiments provide a position pointer that includes a plurality of refill bodies that can be configured at low cost, and ensures freedom from malfunction during exchange of signals with a sensor section of a position detection device. In one embodiment, the position pointer includes a tubular housing having an opening portion, a plurality of refill bodies, a refill body selection mechanism section that selectively causes at least a tip of one of the plurality of refill bodies to project from the opening portion, a magnetic material core, and a coil wound around the magnetic material core. The refill bodies not selected by the refill body selection mechanism section are located away from a through hole of the magnetic material core.
US10589555B2	Printer and method for automatically eliminating slackness of printing medium In accordance with an embodiment, a ribbon holding shaft winds an ink ribbon before printing. A ribbon winding shaft winds the ink ribbon after printing to collect the ink ribbon. A feed motor rotationally drives the ribbon holding shaft. A winding motor rotationally drives the ribbon winding shaft. A detection module detects slackness of the ink ribbon stretched between the ribbon holding shaft and the ribbon winding shaft. A ribbon feed control module forward rotates the winding motor to draw out the ink ribbon from the ribbon holding shaft to the printing section and further controls the ribbon winding shaft to wind the ink ribbon. A reverse rotation control module reversely rotates the feed motor to stretch the ink ribbon between the ribbon holding shaft and the ribbon winding shaft if the detection module detects the slackness of the ink ribbon.
US10589552B2	Imaging device with translatable hinge pin An imaging device including a housing, an access door, and a flap. The housing forms an interior and forms an access door opening and a slotted connection on a side of the access door opening. The access door includes a door cover, an arm extending from the door cover, and a hinge pin. The hinge pin extends outwardly at a terminal end of the arm and matingly couples with the slotted connection. The hinge pin rotates and translates along a length of the slotted connection. The flap is rotatably extendable over the arm.
US10589549B2	Carriage structure and printer Provided are a carriage structure capable of preventing a carriage from contacting a side edge of a print medium, without requiring a discharge roller and facilitating reducing device size, and a printer having the carriage structure. Disposed to a carriage 21 carrying and inkjet head 22 and moving bidirectionally through a range of movement including the conveyance path of a cut-sheet paper S are: a panel member 78 able to protrude in the direction of carriage 21 movement; and a moving mechanism 126 causing the panel member 78 to protrude to the conveyance path of the cut-sheet paper S when the carriage 21 is at a standby position (home position) set in the range of carriage 21 movement.
US10589548B2	Printing apparatus A printing apparatus includes a printing unit that performs printing on a medium, an apparatus main body that houses the printing unit therein and that has outer surfaces including an upper surface and a front surface that adjoiningly intersects the upper surface, a paper feed port that is provided on the upper surface of the apparatus main body and that enables the medium to be fed into the apparatus main body, a feed path that is guiding the medium fed from the paper feed port toward the printing unit and that has a curved portion for inverting the medium during the guiding, a pair of rollers that are provided at the upstream of the curved portion and that feed the medium toward the printing unit via the feed path by rotating while nipping the medium fed from the paper feed port from both front and rear sides.
US10589547B2	Inkjet printer having an aerodynamic element for reducing turbulences An inkjet printer having at least one print head in which an aerodynamic element is placed before (e.g. in a transport direction) a recording medium (e.g. in the form of a sheet or page or plate) to reduce or avoid turbulences that may arise due to the relative motion between print head(s) and recording medium at an edge of the recording medium.
US10589542B2	Thermal transfer printer and method for controlling the same In order to prevent degradation in print quality which can come from matter generated from an ink ribbon and adhering to a thermal head, the thermal transfer printer transports an ink ribbon which has characteristics such that the amount of matter generated from the ink ribbon by transfer and adhering to the thermal head has a peak at predetermined transfer energy and reduces in an energy range higher than the predetermined transfer energy with increase in transfer energy, transfers ink and protective material onto paper in this order from the ink ribbon on which the ink and the protective material are repeatedly arranged in a longitudinal direction thereof, and adjusts transfer energy for the protective material to a value within a predetermined range. The lower limit of the predetermined range is higher than the predetermined transfer energy and minimum energy at which the protective material can be transferred, and is a value sufficient for transfer of the protective material to reduce matter having adhered to the thermal head since transfer of the ink. The upper limit of the predetermined range is lower than an energy value at which the protective material becomes mat and thereby glossiness of a protective layer on the paper formed from the protective material is lost.
US10589536B2	Liquid ejecting module The present invention provides a liquid ejecting module capable of performing stable ejection operation while circulating and supplying fresh ink to the vicinity of ejection ports arranged in high density. To achieve this, a liquid ejecting module includes an element arranged face in which a plurality of ejecting elements are arranged, a circulation flow path including a supply flow path which supplies liquid to a pressure chamber and a collection flow path which collects liquid from the pressure chamber, and a liquid delivery mechanism provided in the circulation flow path for circulating liquid in the pressure chamber. The liquid delivery mechanism is located lower than the element arranged face.
US10589534B2	Inkjet recording apparatus An inkjet recording apparatus includes a recording head, an ink tank, a supply flow path, a supply pump located in the supply flow path, a collection flow path, a relief flow path connecting a first position in the supply flow path to a second position in the supply flow path, wherein the first position is located at a downstream side of the supply pump in the supply flow path and the second position located at an upstream side of the supply pump in the supply flow path, and a differential pressure regulating valve located in the relief flow path and configured to, in a case where the pressure of the pumped ink in the supply flow path is larger than a predetermined value, open the relief flow path so as to allow ink in the supply flow path to flow from the first position to the second position.
US10589533B2	Ink-jet printer There is provided a liquid consuming apparatus including a casing, a liquid consuming section, and a tank. The tank includes a box-shaped body having a light-transmitting property and having five walls and a partition wall; a film adhered to rear end portions of the walls; and a positioning section disposed at least on an outer surface of each of the upper and lower walls, or of each of the right and left walls. In a state that the liquid consuming apparatus is placed on a horizontal plane, the box-shaped body is positioned at a posture at which the positioning section is brought into contact with the casing to thereby allow the front wall to be exposed from a side surface of the casing which extends in a direction crossing the horizontal plane, and at which the rear end portions are located inside the casing.
US10589527B2	Liquid adsorption Example implementations relate to liquid adsorption. In an example, a liquid adsorption system includes a vapor barrier container having a sealable internal volume, a liquid dispensing device in the internal volume, where the liquid dispensing device includes liquid in a liquid flow path extending through at least a portion of the liquid dispensing device to an opening in communication with the internal volume, and a liquid adsorbing material in the internal volume.
US10589522B2	Fluidic die A fluidic die may include a number of actuators. The number of actuators form a number of primitives. The fluidic die may include a digital-to-analog converter (DAC) to drive a number of the delay circuits. The delay circuits delay a number of activation pulses that activate the actuators associated with the primitives to reduce peak power demands of the fluidic die. A number of delay circuits may be coupled to each primitive.
US10589514B2	Screen printing device having conveyance section for discharging and introducing both the screen mask and board support member A printing device including a conveyance rod which discharges and introduces a screen mask and a board support member; and a control section. The control section performs a mask exchange process including a mask discharge process of discharging the screen mask to be discharged and a mask introduction process of introducing the screen mask to be introduced by controlling a conveyance rod. In addition, the control section performs a support member exchange process including a support member discharge process of discharging the board support member to be discharged and a support member introduction process of introducing the support member to be introduced by controlling the conveyance rod.
US10589502B2	Anisotropic conductive film, connected structure, and method for manufacturing a connected structure The present invention is to provide an anisotropic conductive film that excels in dispersing conductive particles and trapping the particles, and maintains conduction reliability even between narrow-pitched terminals. By a method for manufacturing an anisotropic conductive film containing conductive particles, the conductive particles are buried in grooves in a sheet having the grooves regularly formed in the same direction, the conductive particles are arranged, a first resin film having a thermo-setting resin layer formed on a stretchable base film is laminated on the surface of the sheet on the side of the grooves to transfer and attach the conductive particles to the first resin film, the first resin film is uniaxially stretched in a direction other than the direction perpendicular to the array direction of the conductive particles, and a second resin film is laminated.
US10589501B2	Three-dimensional modeling apparatus, production method, and computer program A three-dimensional modeling apparatus includes an ejection portion capable of ejecting a fluid material, which is a material of an object, and a control portion that forms a laminated body in which one layer or more of cross-section bodies are laminated by executing one or more repetitions of a cross-section body formation process, which forms a cross-section body equivalent to one layer of the object by controlling the ejection portion and ejecting the fluid material. The control portion executes a correction process that ejects the fluid material onto a target correction location, which is at least a portion of an outline section of an upper surface of the laminated body.
US10589499B2	Processing machine with a laminating module A processing machine includes: (A) a lamination module including: (A1) a supply roller on which a band carrying a protective film or a layer of varnish to be deposited is wound, (A2) a recovery roller on which the band is wound after the protective film or layer of varnish has been applied to a plastic card, (A3) a heating roller disposed between the supply roller and the recovery roller, (A4) a backing roller disposed against the heating roller, and (A5) a constraining roller; (B) an insertion system defining, with the heating roller, an upstream transfer path along which the plastic card moves as far as the heating roller; (C) a discharge system defining, with the backing roller, a downstream transfer path along which the plastic card moves from the backing roller. The constraining roller is disposed across the downstream transfer path.
US10589497B2	Biaxially oriented polyester film A biaxially orientated polyester film has a PL/VL ratio of 0.3 to 1.2, PL and VL representing the average diameter of the convex portions and the average diameter of the concave portions, respectively, that are defined on the basis of a slice level with a height of 0 nm (reference plane) in a roughness curve determined for at least one surface using a three dimensional surface roughness meter, and the convex portions accounting for an area ratio of 30% to 51% of the reference plane. The biaxially oriented polyester film is excellent in travelling property, slitting property, and dimensional stability, and serves, when used for magnetic recording medium production, to provide a high density magnetic recording medium having a smooth magnetic layer, suffering little dimensional change due to variations in environmental parameters such as temperature and humidity or due to storage, and having good electromagnetic conversion characteristics with little dropout.
US10589496B2	Multilayered polyolefin films, methods of manufacture thereof and articles comprising the same Disclosed herein is a multilayer film comprising two outer layers; where each outer layer comprises polyethylene; two tie layers; where each tie layer comprises a crystalline block composite; where each tie layer has a first face and a second face that are opposed to each other, and where the first face of each tie layer contacts at least one outer layer; and a core layer; where the core layer comprises a polypropylene; where the second face of each tie layer contacts the core layer. Disclosed herein is a method that includes coextruding the aforementioned multilayered film.
US10589491B2	Removable and re-attachable roof system for modular residential construction The present disclosure describes a residential dwelling unit designed for vertical expansion by way of a removable and re-attachable roof system. By removing certain components of the original dwelling unit's roof, that same structure can be converted into the floor of a subsequent vertical addition. Specific components that were removed from the original roof are then re-attached on top of the vertical addition.
US10589490B2	Laminated polyester film A laminated polyester film includes a pigment-containing polyester layer A and wax-containing polyester layers B1 and B2 on both sides of the polyester layer A, wherein the film satisfies formulae (I) and (II), and the coefficient of variation of water contact angle for each layer B1 and layer B2 is not less than 0% and not more than 10%, when the contact angle with water is measured 10 times at arbitrary defined positions within the range of 200 mm×200 mm: Wb1>Wa (I) Wb2>Wa (II) wherein Wb1 and Wb2 represent the wax content per unit area of the layer B1 and layer B2 respectively, and Wa represents the wax content per unit area of the layer A, and wherein the coefficient of variation represents a value obtained by dividing the standard deviation in values measured 10 times by the average value.
US10589487B2	Method for cutting, printing or embossing The invention relates to an apparatus and method for cutting, printing or embossing a continuous sheet of material. The apparatus comprises a tool element, at least two anvils, which are co-operable with the tool element, and a phase adjustment device. The tool element is configured to have a constant surface speed during operation of the apparatus. The apparatus is adapted to receive the continuous sheet at a constant speed into the apparatus, and being adapted to output the continuous sheet at a constant speed from the apparatus. The phase adjustment device is operable to adjust a speed of the continuous sheet within the apparatus in order to adjust a phase of alternate parts of the continuous sheet to be cut, printed or embossed by each anvil as it co-operates with the tool element.
US10589486B2	Device and method for pressing organic material out of waste Device (100) for pressing organic material out of waste, comprising: —a pressing chamber (3) and a first pressing member (4) for compacting introduced waste; —a first feed opening (5) for feeding waste into the pressing chamber (4); —perforations (6) for allowing air, moisture and organic material pressed out of introduced waste to escape from the pressing chamber (3), which perforations (6) are arranged in a wall (9) of the pressing chamber (3) and debouch in a surface (7) bounding the pressing chamber (3); and —a discharge opening (8) for discharging from the pressing chamber (3) compacted waste from which air, moisture and organic material are at least partially removed and whereby the surface lies perpendicularly of the pressing direction of the first pressing member (4). Pressing perpendicularly of the surface (7) results in a more effective and efficient pressing. The device (100) preferably also comprises: —a second feed opening (2) for feeding waste into the device (100); and —an infeed chamber (13), which infeed chamber (13) is located between the first feed opening (5) and the second feed opening (2). A pre-compaction takes place during the displacement of waste fed into the infeed chamber (13) to the pressing chamber (3) via the first feed opening (5), this still further increasing the effectiveness, efficiency and yield of the pressing. Also method for pressing organic material out of waste by means of such a device.
US10589484B2	Press drive comprising two working areas The invention relates to a press drive for a press or a press having a press drive. The invention also relates to a method for controlling the press drive by means of a control unit. The press drive is used for moving a ram of the press in a stroke direction H between an upper return point OT and a lower return point UT. It comprises a knee lever gear having a first lever and a second lever. A connecting rod engages on the knee lever of the two levers and is connected on the other end to an eccentric of an eccentric drive. The control unit can drive the eccentric drive in a first operating mode B1 or a second operating mode B2 or, in particular, also a third operating mode B3. In the first and the second operating modes B1, B2, the eccentric oscillates in a respectively different angle region W1, W2 about a rotation axis D of the eccentric drive, thus resulting in different force and movement states of the ram in both operating modes.
US10589481B2	Mould element comprising a high-contrast texture A mould element (18) intended to be attached in a mould (10) for vulcanizing tires, the mould element (18) having the form of a skin with a thickness (E) comprised between 0.25 and 6 mm and comprising a bearing surface (20) with, on the opposite side, a moulding surface (22) intended to form all or part of the external surface of the tire. The mould element comprises a pattern (30) comprising a plurality of recessed (19, 21, 112) or protruding (106, 107) elements, formed as integral parts of the mould element (18).
US10589477B2	Cosmetic repair of a thermoplastic carbon fiber composite Methods of repairing a defect in a polymeric composite structure are provided. The methods include disposing a patch over a defect in a polymeric composite structure; disposing a textured sheet over the polymeric patch, applying pressure to the polymeric patch and the textured sheet; and heating the polymeric patch. The textured sheet has a surface texture that is a negative of a surface texture of the polymeric composite structure.
US10589476B2	Method and device for producing a three-dimensional fiber composite component A method for producing a three-dimensional fiber composite component with fiber bundles which are shaped from a rod- or strand-like initial shape into a predetermined three-dimensional shape of the component by way of a shape defining apparatus. The shape defining apparatus has at least one shaping channel having a first curvature along its longitudinal direction, which is predetermined for the fiber composite component, and forms at least one leading edge. The fiber bundles are pressed against the at least one leading edge of the shaping channel, thereby adopting the predetermined first curvature.
US10589474B2	Methods for manufacturing sublaminate modules and forming composite laminated structures from the same Variously configured sub-laminate modules are provided, which comprise at least a first ply and a second ply, the first ply comprising fibers extending in a first orientation, the second ply comprising fibers extending in a second orientation. The second orientation is offset relative to the first orientation, which offset defines an acute angle between the two orientations. The acute angle is less than 90 degrees and in at least one embodiment, the acute angle is approximately 25°. In certain embodiments, the acute angle further defines an unbalanced structure of the sub-laminate module. In certain embodiments, the first and second plies may be further secured relative to one another in a non-crimped configuration. Composite laminated structures formed from various embodiments of the sub-laminate modules are also provided, at least some of which may be homogenized. Various methods of manufacturing the sub-laminate modules and the composite laminated structures are also provided.
US10589473B2	Method and apparatus for welding a roofing membrane A machine for welding an overlapped region of two adjacent strips of material and a method of using the same. The machine includes a housing with front and rear ends, a wheel train engaged with the housing for moving the housing across the material; a nozzle on the housing having a welding head at a free end; the nozzle being positionable at least partially beneath the housing's bottom wall for welding the overlapped region; front and rear pressure rollers engaged with the housing, where the front roller is positioned forwardly of the welding head and the rear roller is positioned rearwardly of the welding head; wherein the rear pressure roller applies pressure to the overlapped region when the wheel train moves the housing in a forward direction; and the front pressure roller applies pressure to the overlapped region when the wheel train moves the housing in a reverse direction.
US10589469B2	Method for obtaining a welded joint between elements of different materials, and a hybrid component obtained through this method A welded joint between at least one metal material element and at least one thermoplastic material element is obtained by pressing the elements against each other while applying heat. Contact surfaces of the metal material, which are in contact with the thermoplastic material, are provided with uneven surface portions having a distribution of asperities. With heat applied, the thermoplastic material fills spaces between these asperities and maintains this configuration after subsequent cooling, thereby improving strength of the joint. The uneven surface portions are obtained in a preliminary forming step of the metal material in a press mold, which is configured with a forming surface for generating the uneven surface portions by mechanical deformation and/or with a device for guiding a laser or electron beam. By this technique, hybrid components are obtained made of one or more elements of metal material between which a shaped component of thermoplastic material is interposed.
US10589468B2	Composite rivet blank and installation thereof Composite fasteners, associated blanks and also methods and apparatus for the installation of such fasteners are disclosed. An exemplary composite rivet (10) disclosed comprises an elongated body including braided reinforcement fibers (14) embedded inside the body and supported in a matrix material (16). Also disclosed are structural assemblies comprising composite fasteners and panels or other parts comprising composite and/or other materials.
US10589467B2	Systems and methods for calibration feedback for additive manufacturing Complexity of a geometry of a desired (i.e., target) three-dimensional (3D) object being produced by an additive manufacturing system, as well as atypical behavior of the processes employed by such a system, pose challenges for producing a final version of the desired 3D object with fidelity relative to the desired object. An example embodiment enables such challenges to be overcome as a function of feedback to enable the final version to be produced with fidelity. The feedback may be at least one value that is associated with at least one characteristic of a printed object following processing of the printed object. Such feedback may be obtained as part of a calibration process of the 3D printing system or as part of an operational process of the 3D printing system.
US10589466B2	Systems and methods for implementing multi-layer addressable curing of ultraviolet (UV) light curable inks for three dimensional (3D) printed parts and components A system and method are provided for implementing adjustable curing of layers of deposition materials, including ultraviolet (UV) light or photo curable ink layers, used in the formation and/or manufacture of three-dimensional (3D) printed parts, objects and components, particularly those parts, objects and components formed in 3D printers and additive material manufacturing systems such as 3D jetted ink printing systems. A multi-layer (or layer-by-layer) history of the deposited materials is developed by which to adjust an intensity of an addressable curing unit to provide complete curing to a particular layer without introducing damaging effects that may be caused by over curing the particular layer. The applied curing energy will differently penetrate a number of layers based on constitutions and/or colors of the individual layers in the number of layers to be penetrated. Discrete addressable curing of the individual layered components provides correct curing to the individual layers.
US10589462B2	Three dimensional printing system with improved support fixture A support fixture is provided for forming a three dimensional article of manufacture onto a lower build surface thereof. The formation occurs in a resin vessel containing photocurable resin. The resin vessel includes a transparent sheet that forms a lower bound for the resin. The support fixture includes a lower planar portion, an upper portion, and a side wall coupling the lower planar portion to the upper portion. The lower planar portion defines a dense array of small openings that minimize a fluid drag of lateral resin motion when the lower build surface is proximate to the transparent sheet. The upper portion is for providing alignment and support within the three dimensional printing system. A plurality of large openings formed along the side wall that individually have a cross sectional area that is equal to a combined cross sectional area of a plurality of the small openings.
US10589454B2	Bottle with extended neck finish and method of making same A blow molded synthetic resin bottle has a body and an elongated neck with the body providing a shoulder extending about the base of the neck. The neck has a first collar extending thereabout spaced adjacent the shoulder and at least one additional collar extending thereabout adjacent the upper end of the neck. The resin in the neck is substantially unoriented. To produce the bottle, a synthetic resin preform is injection molded with a generally tubular body and the elongated neck. This preform is placed in a blow mold cavity having a body receiving portion and a neck receiving portion that has a recess extending thereabout seating the first collar therein. The additional collar is disposed outwardly of the mold cavity and is disposed on the upper surface of the mold.
US10589453B2	Device and method for transporting preforms in the region of a blow-molding machine The invention relates to devices and methods for transporting preforms (2) made of a thermoplastic material in the region of a blow-molding (10), having a transport wheel (12) which is mounted in a rotatable manner about a rotational axis and which comprises multiple receiving recess (18) distributed in the circumferential direction over the circumference of the transport wheel for receiving and conveying preforms (20). A hook element (14) is arranged on the transport wheel (12) in the region of each receiving recess (18), said hook element being mounted on the transport wheel (12) in a pivotal manner between an open position and a closed position, and in the closed position, the hook element (14) secures a preform (20) to be transported in the respective receiving recess (18) from falling out of the receiving recess (18).
US10589447B2	Systems and methods for producing materials suitable for additive manufacturing using a hydrodynamic cavitation apparatus Provided in one implementation is a method that includes introducing a volume of raw material into a chamber of a cavitation machine. The raw material can include a mixture comprising a powder and a solvent. The powder can have a first average particle size in the raw material. The method includes applying a hydrodynamic cavitation process to the raw material to produce a product material. The powder can have a second average particle size, smaller than the first average particle size, in the product material. The method includes causing the product material to exit the cavitation chamber and drying the product material to remove the solvent. Apparatus employed to apply the method are also provided.
US10589441B2	Method of producing a laminated wood product, and laminated wood products The present disclosure provides a method of forming a laminated wood product, which is adapted for receiving a load in a direction perpendicular to a principal fiber direction of the wood. The method comprises cutting a log (2) along the principal fiber direction of the log, into a plurality of wood lamellae (20a, 20b), such that the wood lamellae are formed as radial sections of the log, forming the wood lamellae (20a, 20b) to provide each wood lamella with a trapezoidal cross section, whereby the wood lamellae present a respective planar major base surface (bs1) that is formed at a radially outer part of the log (2) and a respective planar minor base surface (bs2) that is formed at a radially inner part of the log (2), arranging the lamellae (20a, 20b) as at least one layer in which planar major base surfaces (bs1) of immediately adjacent lamellae (20a, 20b) face opposite directions, and gluing together the lamellae (20a, 20b) side surface to side surface (ss1, ss2) such that a wood billet is formed. The method further comprises arranging the wood lamellae (20a, b) such that the major base surfaces (bs1) of immediately adjacent wood lamellae taper in opposite directions, and the gluing comprises wet gluing.
US10589440B2	Angle divider for miter saw An angle divider includes a body portion with a proximate end and a distal end. A distal end pivot point is positioned in the distal end of the body portion. First and second removable arm are pivotally mounted to the distal end pivot point. The arms pivot with respect to the distal end pivot point. An adjustable pivot is mounted for sliding movement within an elongated slot formed in the body portion. Brackets removably interconnect the arms to the adjustable pivot. Movement of the arms results in movement of the adjustable pivot longitudinally along the body portion. A lock locks the adjustable pivot with respect to the body portion, which locks the arms in place with respect to the body portion. The removable arms can be removed from the adjustable pivot point for transport and to split the angle.
US10589439B2	Blade mounting and removal tool, system, and product slicer A blade mounting and removal tool, and system, for safely removing a blade from a blade axle of a food product slicer. The blade axle includes a multi-axis locking system for securing the blade to the blade axle. The blade removal tool includes a tool base, a blade engagement assembly, and a blade unlocking assembly. The blade engagement assembly is attached to the tool base and has a blade engagement actuator cooperating with at least one blade engagement retainer. The blade unlocking assembly is also attached to the tool base and has a blade unlocking actuator cooperating with a blade unlocking post.
US10589430B2	Throwable robot with improved drive system A two wheeled throwable robot comprises an elongate chassis with two ends, a motor at each end, drive wheels connected to the motors, and a tail extending from the elongate chassis. The throwable robot includes a pair of torque limiting mechanisms, each torque limiting mechanism being operatively coupled between a motor and a drive wheel. Each torque limiting mechanism comprises a drive flange portion, a driven flange portion and a plurality of rollers. A spring element provides a ring force that biases the rollers toward the driven flange portion.
US10589426B2	Robot A robot including a spherical housing made up of a main housing portion, a first spherical cap portion, and a second spherical cap portion. The main housing portion is disposed between the first spherical cap portion and the second spherical cap portion. The robot further including a weight that is provided in the main housing portion and configured to rotate around a pivot that is orthogonal to a shaft connecting the spherical cap portions. When outputting a response to an input instruction received from a user, via an input device, based on a predetermined processing is determined to require a predetermined time or more, a robot controls a first drive mechanism during the predetermined processing such that the first drive mechanism rotates a weight around the pivot to reciprocally move the weight in the opposite directions of the pivot.
US10589424B2	Robot control device, robot, and robot system A robot control device calculates an evaluation value, based on a partial point cloud included in a plurality of areas corresponding to a gripping unit of a robot for gripping a target object, of a three-dimensional point cloud representing a three-dimensional shape of a surface of the target object. The robot control device calculates a position and an attitude of the gripping unit taken when the gripping unit is made to grip the target object, based on the calculated evaluation value. The robot control device causes the gripping unit to grip the target object, based on the position and the attitude of the gripping unit thus calculated.
US10589422B2	Article conveying apparatus Provided is an article conveying apparatus including a three-dimensional sensor that measures a three-dimensional shape of an article; an adhering portion that is made to adhere to a surface of the article; a moving mechanism that moves a position of the adhering portion in a three-dimensional manner; and a control unit that controls the moving mechanism. The control unit is provided with a center-of-gravity calculating portion that calculates a center of gravity of the article on the basis of the three-dimensional shape of the article measured by the three-dimensional sensor and controls the moving mechanism so as to place the adhering portion in the vicinity of the center of gravity calculated by the center-of-gravity calculating portion.
US10589412B2	Rechargeable electric power tool A rechargeable electric power tool includes a motor that includes a rotation shaft, a motor housing that houses the motor, a gear housing disposed ahead of the motor, a final output shaft that is held onto the gear housing and perpendicular to the rotation shaft, and a loop-shaped handle housing disposed at a rear of the motor housing, and a battery mounting portion configured to hold two battery packs is disposed at a rear portion of the handle housing.
US10589407B2	Optimized method for setting expansion anchors by means of a power tool A method for setting an expansion anchor by a power tool, and a power tool that performs the method, is disclosed. In an embodiment, the method includes exerting rotary impacts on the expansion anchor in order to expand an expansion sleeve in dependence on a first rotational speed until a tightening torque corresponds to a threshold value, exerting a predetermined number of rotary impacts on the expansion anchor in dependence on the first rotational speed, and exerting rotary impacts on the expansion anchor by the power tool in dependence on a generated second rotational speed for a predetermined period of time.
US10589406B2	Guidance device and method for installing flanges The invention relates to a guidance device for guiding a worker through a process of installing flanges by fastening a plurality of bolts with a torque wrench. The guidance device is arranged to communicate with the torque wrench and the worker via a user interface. The guidance device is arranged to a) obtain flange information about a flange to be installed, the flange information comprising a required torqueing pattern of the bolts to be fastened and required torque values, b) output via the user interface of an indication of a first bolt of the required torqueing pattern, c) receive an applied torque value from the torque wrench, d) output via the user interface of an indication of a next bolt of the required torqueing pattern, repeat c) and d) until a last applied torque value is received and e) transmit a torque record to a remote computer or data storage.
US10589404B2	Wrench Disclosed is a wrench, which is used for wrenching a workpiece and comprises a unidirectional transmission mechanism. The unidirectional transmission mechanism comprises rollers, a first member and a second member at least partially sheathed in the first member. The first member is fixedly provided at a wrenching portion of the wrench, and the second member is used for mating with the workpiece. The directions of the rotating torque from the wrenching portion are a first direction and a second direction along the axis of rotation of the first member. With regard to one of the rotating torque of the first direction and the rotating torque of the second direction, the second member is stationary relative to the first member so as to output the rotating torque to the workpiece; and with regard to the other one thereof, the second member rotates relative to the first member without outputting the rotating torque to the workpiece. The torque of the unidirectional transmission mechanism can meet the demand of using a wrench, and at the same time, the unidirectional transmission mechanism remains silent in use and has the characteristic of wear resistance of bearings.
US10589402B2	Abrasive articles and methods of forming the same An abrasive article is provided that may include a body. The body may include a bond component and abrasive particles within the bond component. The bond component may include a Fe—Co—Cu—Ni—Sn based bond material and a performance enhancing material. The performance enhancing material may include hex-boron nitride. The content of the performance enhancing material may be at least about 6 vol. % and not greater than about 14 vol. % for a total volume of the bond component.
US10589399B2	Textured small pad for chemical mechanical polishing A chemical mechanical polishing system includes a substrate support configured to hold a substrate, a polishing pad assembly include a membrane and a polishing pad portion having a polishing surface, a polishing pad carrier, and a drive system configured to cause relative motion between the substrate support and the polishing pad carrier. The polishing pad portion is joined to the membrane on a side opposite the polishing surface. The polishing surface has a width parallel to the polishing surface at least four times smaller than a diameter of the substrate. An outer surface of the polishing pad portion includes at least one recess and at least one plateau having a top surface that provides the polishing surface. The polishing surface has a plurality of edges defined by intersections between side walls of the at least one recess and a top surface of the at least one plateau.
US10589398B2	Heat exchanger for regulating surface temperature of a polishing pad, polishing apparatus, polishing method, and medium storing computer program A heat exchanger which can allow a surface temperature of a polishing pad to promptly reach a target temperature and can realize a uniform distribution of the surface temperature of the polishing pad is disclosed. The heat exchanger includes a pad contact surface capable of contacting the polishing pad, a heating flow passage through which a heating fluid is to flow, and a cooling flow passage through which a cooling fluid is to flow. The heating flow passage and the cooling flow passage are arranged side by side from beginnings to ends thereof, and the heating flow passage and the cooling flow passage cross each other at different levels at a peripheral portion of the pad contact surface.
US10589395B2	System and method for detecting damaged tool of multi-axis head machining equipment A system for detecting a damaged tool of multi-axis head machining equipment includes multi-axis head machining equipment, and a damaged tool detecting device connected to the multi-axis head machining equipment to detect a damaged tool, the damaged tool detecting device being configured to measure a current and a current change amount of the multi-axis head machining equipment to monitor a machining load, and a derivative and machining energy of the machining load, so as to detect whether there is an abnormality in a plurality of tools mounted on a multi-axis head during machining.
US10589390B2	Rigging table for assembling trusses and method of use thereof A rigging table and system for assembling trusses using a rigging table. An embodiment of a rigging table includes a base having a generally longitudinal axis and a generally lateral extent, and at least two bunk assemblies moveable along the base in at least the generally longitudinal axis such that each bunk assembly is capable of being positioned on the base relative to another bunk assembly. Each bunk assembly may include a frame extending along the lateral extent of the base, a pair of guides slidably positioned on the frame to move generally transverse to the longitudinal axis of the base toward and away from each other and able to be fastened in position on the frame, and a pair of automated clamp members each positioned relative to and moveable with one of the guides on the frame, to accommodate assembly of different sized trusses.
US10589389B2	Apparatus and method for cooling a hard metal applied to the surface of a metal alloy substrate An apparatus and related method for cooling a hard metal applied in a molten or semi-molten state to the surface of a metal substrate employ a chill block chilled by a cryogenic coolant conducted through a coolant passage in the chill block with at least one ejector port in communication with the coolant passage arranged to eject cryogenic coolant from the chill block onto the hand metal for further cooling the hard metal. An alloy steel substrate preheated to 300 to 600 degrees Fahrenheit has a hard metal applied thereto by an arc welding process.
US10589388B2	Systems and methods for low-manganese welding alloys Systems and methods for low-manganese welding alloys are disclosed. An example arc welding consumable that forms a weld deposit on a steel workpiece during an arc welding operation, wherein the welding consumable comprises: less than 0.4 wt % manganese; strengthening agents selected from the group consisting of nickel, cobalt, copper, carbon, molybdenum, chromium, vanadium, silicon, and boron; and grain control agents selected from the group consisting of niobium, tantalum, titanium, zirconium, and boron, wherein the grain control agents comprise greater than 0.06 wt % and less than 0.6 wt % of the welding consumable, wherein the weld deposit comprises a tensile strength greater than or equal to 70 ksi, a yield strength greater than or equal to 58 ksi, a ductility, as measured by percent elongation, that is at least 22%, and a Charpy V-notch toughness greater than or equal to 20 ft-lbs at −20° F., and wherein the welding consumable provides a manganese fume generation rate less than 0.01 grams per minute during the arc welding operation.
US10589384B2	Processing of material using non-circular laser beams Method for processing of material by use of a pulsed laser Each laser pulse is shaped regarding its beam profile so that a cross sectional area, which is defined by a cross section of the laser pulse in its focal point orthogonal to its propagation direction, is of particular shape and has a main extension axis of greater extent than its minor extension axis. One major crack is effected by each laser pulse, the major crack having a lateral extension basically oriented according to the main extension axis of the respective pulse in the focal point. Furthermore, each laser pulse is emitted so that the orientation of its main extension axis in the focal point corresponds to a pre-defined orientation relative to an orientation of a respective tangent to the processing path at the assigned processing point.
US10589383B2	Cutting position adjustment for cutting head A laser cutting machine includes at least one galvo having a galvo field of view in which the galvo can cut a material moving with a speed past the galvo. A display in the machine provides an image of at least one pattern to be cut from a material, the pattern comprising of a plurality of objects with each object having a position on the material and each object comprising at least one cut. An optimizer in the machine receives the position on the material of each object of the pattern and assigns a start locations for each cut of each object and a trigger distance for each object to maximize the speed at which the material moves past the galvo while ensuring that each object is cut by the galvo at the object's respective position on the material.
US10589382B2	Overlapping border and internal sections of object formed by different AM melting beam sources in overlapping field region A method for additive manufacturing an object is disclosed. The method includes, for a first portion of the object to be built in a first overlapping field region of a plurality of melting beams of a metal powder AM system, sequentially forming each layer of the first portion by: forming only a border section of the first portion of the object using a first melting beam of the plurality of melting beams in the first overlapping field region; and forming an internal section of the first portion of the object within the border section using at least one second, different melting beam from the first melting beam in the first overlapping field region. An entirety of an internal edge of the border section of the first portion of the object is overlapped with an entirety of an external edge of the internal section of the first portion of the object.
US10589381B2	Method for producing a dental or medical instrument The invention relates to a method for producing an instrument, in particular a dental instrument or a medical instrument, in which method a blank is produced and is subsequently coated at least partially with abrasive particles, wherein the abrasive particles, in a mixture with carrier particles, are fed onto the surface to be coated and are melted onto the surface by means of a laser.
US10589380B2	Lap welding method, lap joint, production method of lap joint, and an automobile part The present invention has as its object to inhibit fracture due to a HAZ softened part in substantially circular laser lap welding taking the place of resistance spot welding for joining a superposed plurality of steel sheets including a high strength steel sheet.To solve this problem, the inventors discovered lap welding comprising superposing a plurality of steel sheets and firing a laser to form a substantially circular laser weld (1), which lap welding firing the laser in a straight line through an outer edge of the substantially circular laser weld (1) so as to form a hardened part (8) at the steel sheets and thereby suppressing fracture arising from the HAZ softened part.
US10589377B2	Additive manufacturing in metals with a fiber array laser source and adaptive multi-beam shaping A system for LAM that uses a scalable array of individually controllable laser beams that are generated by a fiber array system to process materials into an object using a powder bed, wire feed, or direct deposition. The adaptive control of individual beams may include beam power, focal spot width, centroid position, scanning orientation, amplitude and frequency, piston phase and polarization states of individual beams. These characteristics can be independently adjusted to control LAM characteristics including microstructure, mechanical and surface quality characteristics. The system may also have a set of material sensors that gather information on a material and environment immediately before, during, and immediately after processing. This information can be used to adapt the material processing routine to improve LAM productivity and parts quality. The system also supports a variety of beam shaping methods that improve the quality of produced objects or mitigate processing issues.
US10589376B2	Base part of a mold for welding metal rails The invention relates to base part of a mold for aluminothermic welding of metal rails, which base part generally has a rectangular parallelepiped and has an upper face for receiving the foot of said rails, this upper face having a hollow cavity comprising a base, two opposing longitudinal side walls, and two opposing transverse side walls. The invention is characterized in that each of said longitudinal side walls has an intermediate region surrounded by two end regions, and these end regions are located in the same plane, whereas the intermediate region has a curved profile, the well of which is directed towards the opposite side wall.
US10589374B2	Welding auxiliary joining part with a plastically deformable tip region; method for connecting components with this welding auxiliary joining part A welding auxiliary joining part in the shape of a stud having a head, a shank and a tip is disclosed. The welding auxiliary joining part is driven into a component made of a non- or poorly weldable material by means of a setting method. A welding head is created during driving-in due to mechanical deformation such that subsequently the component can be connected by welding via the welding auxiliary joining part to a further component made of a weldable material.
US10589370B2	Automatic blocked hole identification A method for hole formation using an electrical discharge machining tool configured to penetrate metal. The method includes the steps of: penetrating the metal using an electrode to form a hole by moving the electrode away from a starting point; verifying that the hole is complete using the electrical discharge machine; and wherein the verifying step includes the step of probing the hole with the electrode.
US10589366B2	Table saw insert with lock-down mechanism Inserts for table saws are disclosed. The table inserts are equipped with a toolless locking mechanism that mechanically holds the insert in place and which allows for the installation and removal of the insert without the use of tools. The locking mechanism is easy to lock and unlock and yet robust enough to hold a zero-clearance insert in place.
US10589360B2	Systems of articles of manufacture with corresponding fiducial marks and dimensional variations The illustrative embodiment of the present invention uses a tangible three-dimensional structure as a fiducial mark, which structure is, at least partially, tolerant of dimensional variations in the article. The illustrative embodiment uses three such tangible three-dimensional structures: (1) a portion of a tangible conical surface, (2) a portion of a tangible spheroidal surface, and (3) a portion of a tangible pyramidal surface.
US10589359B2	Apparatus and method for enlarging inner diameter of injector for reactor A drill assembly and method is provided for enlarging an injector of a reactor. The drill assembly includes an elongated shaft attached to a piloted drill bit including a pilot portion distal from and extending colinearly with the elongated shaft and a cutting portion proximal the elongated shaft and positioned between the pilot portion and the elongated shaft, wherein the cutting portion includes at least one cutting edge extending radially from a center axis of rotation beyond an outer surface of the pilot portion; and a drive device adapted to rotate the elongated shaft about the axis of rotation. The method includes inserting the pilot portion into an injector; and cutting away a portion of an inner surface of the injector with the cutting portion.
US10589354B2	Systems and methods for depositing charged metal droplets onto a workpiece Apparatus and methods are described for performing additive manufacturing. The apparatus includes a vacuum chamber for fabricating a workpiece composed of deposited metal, a table positioned within the vacuum chamber, and configured to support fabrication of the workpiece on a substrate, and one or more multiple droplet emitters coupled to the vacuum chamber, and arranged to irradiate the workpiece with a stream of molten metal droplets during fabrication.
US10589353B2	Datum structure for additively manufactured object removal from build platform An additively manufactured (AM) structure includes a removal plane extending therein defining an object thereabove. The AM structure also includes at least one datum structure coupled relative to the AM structure. Each datum structure includes a vertical reference plane for guiding a cutting element to remove the object from a remaining portion of the AM structure through the removal plane. The vertical reference plane is horizontally coplanar with the removal plane of the AM structure. The datum structures allow for accurate object cuts regardless of whether an AM build platform is horizontal or non-planar.
US10589349B2	Production of metallic glass objects by melt deposition Methods and apparatus for forming high aspect ratio metallic glass objects, including metallic glass sheets and tubes, by a melt deposition process are provided. In some methods and apparatus a molten alloy is deposited inside a channel formed by two substrates moving relative to each other, and shaped and quenched by conduction to the substrates in a manner that enables the molten alloy to vitrify without undergoing substantial shear flow.
US10589346B2	Use of a feeder insert and method for manufacturing a casting mold having a vertical mold separation A use of a feeder insert, having a volumetric center of gravity which is offset in relation to the opening axis of the passage opening of said feeder insert, in the manufacture of a casting mold having a vertical mold separation and a feeder insert which for dense feeding of the mold cavity during the casting procedure is attached to the casting mold, is described, wherein the feeder insert is positioned in a prefabricated mold part of the casting mold such that the opening axis of said feeder insert runs below the volumetric center of gravity of the latter.
US10589344B2	Mold compositions and methods for casting titanium and titanium aluminide alloys A method for forming a mold for casting a titanium-containing article, the method including combining calcium aluminate with a liquid to produce an initial slurry of calcium aluminate and adding oxide particles into the initial slurry to create a final slurry. The method further includes introducing the final slurry into a mold cavity that contains a fugitive pattern and allowing the final slurry to cure in the mold cavity to form a mold of a titanium-containing article.
US10589343B2	Apparatus and method for forming an antipollution device housing A tool assembly for forming a workpiece with an outer surface into a housing with a non-round design outer profile. The tool assembly includes a number of jaw segments, each jaw segment having an internal surface for engaging the outer surface. The jaw segments are movable between a first condition and a second condition, in which the internal surfaces of the jaw segments substantially define the design outer profile of the housing. Each internal surface has a preselected end point associated therewith defined by a radius centered on the preselected end point that is substantially coincident with the portion of the design outer profile defined by the internal surface. Each jaw segment is movable toward the preselected end point therefor when moved from the first condition to the second condition, and away from the preselected end point therefor when moved from the second condition to the first condition.
US10589341B2	Multi-step joining device and joining method therefor A joining device, in particular a self-piercing rivet tool, is disclosed that is operated with the assistance of different drive steps. These drive steps comprise at least one movement step with a fast punch speed, and a power step with a low punch speed and strong punch force. In combination with the joining device, a clamping device module is use that, based on the at least one spring in the clamping device module, generates discernible threshold values in the force/punch path diagram, with the assistance of which a switchover between different drive steps of the joining device is activated. Moreover, the present disclosure relates to a joining method for the above-described joining device.
US10589340B2	Punch rivet supply device and punch riveting device A supply device for a joining element which has a shaft, extending along a joining element axis with a first diameter, and an adjacent head with a second diameter which is greater than the first diameter. The supply device comprising a base enclosing a first joining element channel, a second joining element channel and a third joining element channel, which are at least partially arranged in a common channel plane, and which each have a cross-section which is adapted to the shape of the joining element. And the first and the second joining element channels are orientated relative to each other at a switching angle which is in a range from 5° to 45°, while the first and the second joining element channels merge into the third joining element channel at a junction with a switching arrangement.
US10589338B1	Feed assembly for automated machines An assembly for feeding objects downstream into an automated machine includes a track, a tamping location on the track, a stop disposed at the tamping location, and a forward path through the track. A spring proximate to the tamping location moves between a first position and a second position. In the first position of the spring, the spring cooperates with the stop to interrupt the forward path. In the second position of the spring, the spring cooperates with the stop to open the forward path to allow objects to move downstream in the track.
US10589336B2	Foil configuring device and method of cooking A device for configuring foil for use in cooking food comprising a base portion comprising first and second portions, a first plurality of elements operatively associated with the first portion; and a second plurality of elements operatively associated with the second portion; at least one of the first or second plurality of elements operating to move for entry of foil therebetween; the first and second plurality of elements operating to configure foil as the foil passes between the first and second plurality of elements. A method of cooking using configured foil.
US10589325B2	Cooking appliance with a pan and a method for cleaning the pan A method for cleaning the cooking space of a cooking appliance with a pan including adding a cleaning agent to the cooking space and if necessary, after this agent has been allowed to work for a certain period of time, a liquid jet is introduced under high pressure from the a spray head of a cleaning device through the at least one spray nozzle, which rotates around an axis perpendicular to the rotational axis of the spray head rotating around this axis. The liquid jet consists exclusively of water and which swirls and splashes the cleaning agent, and if necessary, after this splashed agent has been allowed to work for a further certain period of time, removes the residues mechanically from the bottom, the walls, and the inside surface of the lid, andwherein said residues are then carried away together with the washing solution out of the cooking space via the drain.
US10589324B2	Cleaning of process equipment A method of cleaning fouled process equipment which includes a process vessel (10) fouled by an organic foulant, includes spraying a hydrocarbon stream at a pressure of at least 69 bar(g) at fouled surfaces inside the process vessel (10) thereby to dislodge the organic foulant from the fouled surfaces. The hydrocarbon stream is sprayed from at least one nozzle (24) located inside the process vessel (10). The hydrocarbon stream is at a temperature below the melting point of the organic foulant or below the melting point of a major component of the organic foulant when the organic foulant is a multi-component organic foulant. The dislodged foulant is removed from the process vessel (10).
US10589323B2	Snow adhesion preventing device and signaling apparatus There is provided a signaling apparatus including a plurality of LED elements provided in a signal lamp body; a transparent panel provided in the LED elements and configured to transmit outgoing light from the LED elements on a rear side to a front surface to which snow adheres; a frame unit provided on an outer periphery of the panel; and vibration generators provided in the frame unit and configured to vibrate the panel.
US10589321B2	Method of, and an apparatus for, rinsing materialographic samples The present invention relates to a method of, and an apparatus for, rinsing materialographic samples. The method includes the steps of: arranging one or more materialographic samples in a sample holder; connecting the sample holder (10) to a rotation head of a rinsing device; placing the sample holder connected to the rotation head in the vessel of the rinsing device; rotating the sample holder relative to the vessel; filling the vessel with a rinsing liquid; and subjecting the materialographic samples in the sample holder to ultrasonic waves.
US10589320B1	System comprising a portable switching device for use with a portable electronic device A lens and/or a view screen of an electronic device having at least one case can be cleaned by wiping the view screen with a cleaning component wherein the cleaning component is configured to selectively couple to the at least one case or some other substrate using a magnetic attractive force. The cleaning devices may have secondary applications such as securing fly fishing lures, activating or deactivating a device having a magnetic switch, or preventing sunglasses from sinking. They may also be manufactured without a cleaning component for use with the secondary applications.
US10589318B2	Classifying polysilicon A method for mechanically classifying polycrystalline silicon chunks or granules with a vibratory screening machine, involves setting silicon chunks or granules present on one or more screens each comprising a screen lining in vibration such that the silicon chunks or silicon granules perform a movement which causes the silicon chunks or silicon granules to be separated into various size classes, wherein a screening index is greater than or equal to 0.6 and less than or equal to 9.0.
US10589317B2	Micromachined ultrasonic transducer arrays with multiple harmonic modes Micromachined ultrasonic transducer (MUT) arrays capable of multiple resonant modes and techniques for operating them are described, for example to achieve both high frequency and low frequency operation in a same device. In embodiments, various sizes of piezoelectric membranes are fabricated for tuning resonance frequency across the membranes. The variously sized piezoelectric membranes are gradually transitioned across a length of the substrate to mitigate destructive interference between membranes oscillating in different modes and frequencies.
US10589316B2	Waterproof coating with nanoscopic/microscopic features and methods of making same A process of fabricating the waterproof coating may include selecting a substrate, utilizing a sol-gel comprising a silane or silane derivative and metal oxide precursor to coat the substrate, and optionally coating the substrate with a hydrophobic chemical agent and/or other chemical agents to create a surface with nanoscopic or microscopic features. The process may utilize an all solution process or controlled environment for fabricating self-cleaning and waterproof coating that prevent wetting or staining of a substrate, or may utilize a controlled environment.
US10589313B2	Apparatus and method for batch spray coating of surgical needles Novel apparatus and methods for coating surgical needles in batch processes are disclosed. The apparatus and methods are particularly useful for applying uniform silicone lubricious coatings to surgical needles in bulk quantities using a novel separation and spray coating system and method.
US10589312B2	Housing and dispenser A housing for a dispenser includes two non-metal half shells forming respective sides of at least a front part of the housing, with the front part of the housing including a cartridge receptacle, and with the two non-metal half shells being connected to one another. The housing further includes a reinforcing plate forming at least part of a front end of the cartridge receptacle, with the reinforcing plate being received between the two non-metal half shells and including a retainer configured to connect the two non-metal half shells at the front end of the cartridge receptacle.
US10589311B1	Apparatus for finishing drywall without sanding A drywall finishing apparatus includes a water reservoir connected to a water distribution element. The water distribution element applies water to a finishing pad. The finishing pad is designed to allow water to flow through and reconstitute already applied drywall mud. The reconstituted drywall mud can then be smoothed out with the finishing pad. The finishing pad creates a hydroplaning effect to glide over the drywall mud.
US10589308B2	Finger rest for a liquid applicator A finger rest for a liquid applicator is presented. The finger rest comprises a base. The finger rest also comprises an aperture configured to receive a handle of the liquid applicator. The base is configured to rotationally align with a head of the liquid applicator at a junction.
US10589307B2	Plants for treating motor-vehicle bodies and/or motor-vehicle components A station for treating objects may include: a booth including at least one entrance for an object and at least one exit for the object; a system configured to move the object between the at least one entrance and the at least one exit; at least one robot configured to treat the object in the booth; and/or a platform configured to support the object. The platform may be configured to rotate about a vertical axis so as to rotate the object inside the booth relative to the at least one robot. The at least one entrance may not be aligned with the at least one exit. The system may be configured to rotate with the platform so as to align with the at least one entrance in order to receive the object, and so as to align with the at least one exit in order to release the object.
US10589305B2	Substrate treating apparatus, and method of controlling the substrate treating apparatus In a coating apparatus, a nozzle moving mechanism selectively grips any one of a plurality of coating solution nozzles, moves the gripped coating solution nozzle and a solvent nozzle together, and moves at least the solvent nozzle to a solvent suction unit. The moved solvent nozzle is caused to dispense a solvent to the solvent suction unit, and the gripped coating solution nozzle is caused to suck the solvent retained in the same solvent suction unit to which the solvent has been dispensed. Thus, since dispensation and suction of the solvent are done in the same solvent suction unit, the quantity of the solvent used can be held down. Further, a supply line for supplying the solvent does not need to be provided for the suction unit. The construction of the suction unit can therefore be made simple, and its cost can be held down.
US10589304B1	Combination animal deterrent canister and carrier device An animal deterrent canister with a pressurized vessel containing animal deterrent and a nozzle assembly with a flange, an actuator actuated by a downward pressure, and a nozzle for releasing animal deterrent from the pressurized vessel cooperates with a carrier device. The carrier device has a mounting structure for mounting to an object, a receiver for receiving the nozzle assembly of the animal deterrent canister, an actuator pin that moves between a retracted position away from the actuator and an extended position that depresses the actuator, and a cable housed within a sleeve. The receiver has an engagement profile that receives the flange in an interference engagement. One end of the cable is connected to the actuator pin and the other end is connected to a hand actuator that applies a compressive force to the cable relative to the sleeve to move the actuator pin to the extended position.
US10589300B2	Coating system and method An atomizing spray device includes a housing having plural inlets and one or more outlets fluidly coupled with each other by an interior chamber. The inlets include a first inlet shaped to receive a first fluid and a second inlet shaped to receive a slurry of ceramic particles and a second fluid. The interior chamber in the housing is shaped to mix the first fluid received via the first inlet with the slurry received via the second inlet inside the housing to form a mixture in a location between the inlets and the one or more outlets. The interior chamber in the housing also is shaped to direct the mixture formed inside the housing as droplets outside of the housing via the one or more outlets such that, based on a discharged amount of the first fluid in the droplets, the first fluid promotes evaporation of the second fluid as the droplets traverse from the housing toward a surface of a component.
US10589295B2	Apparatus and process for separating a solids/fluid mixture It is disclosed an apparatus for separating a least one solid from a solids/fluid mixture, said apparatus comprising a separation chamber and a cushion chamber. The separation chamber comprises a top end, a bottom end, at least one wall, and an inlet port for introducing the solids/fluid mixture, said inlet port having an inlet port vector. The cushion chamber comprises at least one boundary wall, and it is adapted to maintain a cushion of the solids/fluid mixture at an intersection of the inlet port vector and the cushion chamber when the separation chamber and the cushion chamber are connected by a communication port at the intersection of the inlet port vector and the at least one wall. The communication port has an area at least a size of an impact area of the solids/fluid mixture on the at least one wall. The communication port may be formed by the erosion of the at least one wall of the separation chamber caused by the solids/fluid mixture at the impact area.It is also disclosed a process for separating a solids/fluid mixture, wherein the solids/fluid mixture is introduced through the inlet port of the separation chamber and contacted with a cushion of a previously introduced solids/fluid mixture, the solids/fluid mixture being allowed to interact with the cushion of the previously introduced solids/fluid mixture. The at least one solid is separated from the fluid by density difference in the separation chamber. Preferably, the solids/fluid mixture is steam treated lignocellulosic biomass which is inserted in the disclosed apparatus at high velocity.
US10589293B2	Moderately oxidized polysaccharide depressants for use in iron ore flotation processes Depressants comprising a moderately oxidized polysaccharide having about 0.05 to about 4.5 mmol of anionic charge per gram at a pH of about 6 to about 7, or about 0.2 to about 5 mmol of anionic charge per gram at a pH of about 10 to about 11.2, are provided. Also disclosed are processes for enriching a desired mineral from an ore comprising the desired mineral and gangue, wherein the process comprises carrying out a flotation process in the presence of one or more of the depressants.
US10589291B2	Hydraulic classifiers Hydraulic classifiers are provided for sorting material using injected water. Some embodiments include upper and lower housings having different cross-sectional shapes. In some embodiments, certain improvements are provided for cleanout and/or removal or replacement of teeter bars.
US10589290B2	Waste processing machine feed assist system A waste processing machine for reducing material and having a feed assist system. A cutting assembly on a frame reduces material. A feed system on the frame directs material toward the cutting assembly. A winch assembly includes a line with a line end for securing material, and a driver on the frame to urge the line end toward the driver. A keeper fixed to the frame secures the line end. A sensor detects utilization between: a docked configuration with the line tensioned against between the driver and the keeper; and an undocked configuration with the line loosened. A control unit allows operation of the feed system in the docked configuration, and interrupts the feed system in the undocked configuration. A feed mechanism actuation bypasses the interrupted operation to advance material for a bypass period, and a limit mechanism overrides operation of the feed mechanism for a subsequent limit period.
US10589289B2	Method for controlling the operation of a crusher, a mineral material processing plant and a control system A method for controlling the operation of a crusher, a mineral material processing plant and a control system. The method including measuring a quantity related to stress to which the crusher is exposed during the crushing of material, determining a deviation value of the quantity related to stress, comparing the determined deviation value to a reference deviation value, and in response to the deviation value differing from the reference deviation value, adjusting a default setting of the quantity related to stress.
US10589280B2	Mill roller and pulverizer A mill roller (6) is provided with a roller main body (62) that rotates about an inclined axis line (O2) and has an outer peripheral surface (64) for pulverizing an object to be crushed against the mill table (4). The outer peripheral surface (64) is convex outward in a radial direction of the roller main body (62). The outer peripheral surface (64) has a first outer peripheral surface (641) and a second outer peripheral surface (642). The first outer peripheral surface (641) has an arcuate shape formed to have the same radius of curvature on both sides of a maximum outer diameter point (A). The second outer peripheral surface (642) is further receded inward in the radial direction than an imaginary circle running along the first outer peripheral surface (641).
US10589279B2	Water relief groove to prevent cavitation of opposite refiner plate This disclosure relates to a refiner plate segment, mechanical refiners, and methods to manufacture a refiner plate segment having one or more water channels disposed in a variable substrate profile along the radial length of a refiner plate segment base and disposed between the refiner plate segment inlet and the primary refining section, wherein the variable substrate profile comprises an undulating curve configured to complement a second undulating curve on an opposing refiner plate, and wherein dimensions of the one or more water channels are sufficiently narrow to prevent wood chips from entering the water channels and sufficiently wide to provide a bypass path for the free water.
US10589274B2	Microfluidic devices and methods of their use Methods and systems for manipulating drops in microfluidic channels are provided.
US10589270B2	Digital fluid sample separation apparatus and methods for one-step quantitative sample analysis A Digital Separation (DS) chip for separating, digitizing and analyzing a fluid sample is presented. The DS chip includes a fluidic layer that prepares and compartmentalizes the fluid sample for analysis. Cliff structures that are adjacent to wells skim the fluid sample and prevent particles, which may interfere with fluid sample analysis, from entering the wells. Skimmed fluid sample analysis occurs in the wells and endpoint data can be collected and used to determine an original concentration of a desired component in the fluid sample very quickly. Using the described apparatus and methods, a fluid sample can be prepared, digitized, compartmentalized, assayed and the endpoint data collected in ˜30 minutes. The apparatus and methods can easily be adapted to provide parallel processing of a sample.
US10589268B2	Method and device for processing tissues and cells Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
US10589267B2	System for portable and easy-to-use detection of analytes with mobile computing device This system takes in raw cellular material collected using a provided swab, blood collection device, urine collection device, or other sample collection device and transforms that biological material into a digital result, identifying the presence, absence and/or quantity of nucleic acids, proteins, and/or other molecules of interest.
US10589265B2	Reagent storage in microfluidic systems and related articles and methods Fluidic devices and methods including those that provide storage and/or facilitate fluid handling of reagents are provided. Fluidic devices described herein may include channel segments positioned on two sides of an article, optionally connected by an intervening channel passing through the article. The channel segments may be used to store reagents in the device prior to first use by an end user. The stored reagents may include fluid plugs positioned in linear order so that during use, as fluids flow to a reaction site, they are delivered in a predetermined sequence. The specific geometries of the channel segments and the positions of the channel segments within the fluidic devices described herein may allow fluid reagents to be stored for extended periods of time without mixing, even during routine handling of the devices such as during shipping of the devices, and when the devices are subjected to physical shock or vibration.
US10589262B2	Method of producing proton pump inhibitor compound having optical activity A highly pure optically active proton pump inhibitor compound can be produced safely and inexpensively in a high yield and enantioselectivity by a method of producing an optically active sulfoxide of Formula 2 or a salt thereof, comprising oxidizing a sulfide of Formula 1 or a salt thereof with hydrogen peroxide using an iron salt in the presence of a chiral ligand of Formula 3; wherein A is CH or N; R1 is hydrogen atom, an alkyl optionally substituted by halogen(s), or an alkoxy optionally substituted by halogen(s); one to three R2 may exist, and each of R2 is independently an alkyl, a dialkylamino, or an alkoxy optionally substituted by halogen(s) or alkoxy(s); each of R3 is independently hydrogen atom, a halogen, cyano or the like; R4 is a tertiary alkyl; and * and ** represent respectively R configuration or S configuration.
US10589256B2	Selective hydrogenation catalyst and selective hydrogenation method using the same The present invention relates to a Ru—Pd bimetallic catalyst for use in hydrogenation of a compound, and more particularly to a catalyst prepared by loading both ruthenium and palladium on a g-C3N4 support and to a selective hydrogenation process of a pyridine group in a reaction system containing both a pyridine group and a benzene group using the catalyst.
US10589255B1	Tantalum vanadate nanorods and methods of their make and use Tantalum vanadate (TaVO5) forms into nanostructures, particularly nanorods, which may range in length between 100 and 600 nm with a length:width ratio between 20:1 to 50:1, and, as a bulk material, have a bandgap of 1.5 to 3.00 eV. Such nanostructures may be prepared by the hydrothermal method.
US10589253B2	Method for preparing a sorbent A method is described for preparing a sorbent including the steps of: (i) mixing together a particulate copper sulphide material, a particulate support material and one or more binders, (ii) shaping the mixture, and (iii) drying the shaped mixture to form a dried sorbent.
US10589252B2	Simultaneous on-site production of hydrogen peroxide and nitrogen oxides from air and water in a low power flowing liquid film plasma discharge for use in agriculture A reactor system that includes a single reactor or a plurality of parallel reactors. A method that includes injecting a mixture including liquid water and a gas, into at least one electrically-conductive inlet capillary tube of a continuously-flowing plasma reactor to generate a flowing liquid film region on one or more internal walls of the continuously-flowing plasma reactor with a gas stream flowing through the flowing liquid film region; propagating a plasma discharge along the flowing liquid film region from at least one electrically-conductive inlet capillary to an electrically-conductive outlet capillary tube at an opposing end of the continuously-flowing plasma reactor; dissociating the liquid water in the plasma discharge to form a plurality of dissociation products; producing hydrogen peroxide and nitrogen oxides from the plurality of dissociation products.
US10589250B2	Automated purification and formulation device for radiopharmaceutical compounds A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer.
US10589249B2	Apparatus for controlling the temperature of a reactor A heat exchanger system can be used for removal or introduction of heat from or into a chemical reactor in which a chemical reaction is proceeding. The system further provides an apparatus for controlling the temperature of a reactor and a process for performing a chemical reaction, in each case using a heat exchanger system with a thermally insulated inner tube.
US10589246B2	High temperature inlet distributor A system for processing one or more materials includes a processor having a shell defining a chamber and a plurality of serially stacked pipe assemblies. Each pipe assembly includes a header having at least one substantially straight pipe section receiving a fluid; and a plurality of nozzles in fluid communication with and projecting downwardly from the header. The nozzles direct the fluid into the chamber of the processor.
US10589243B2	Catalytic reactor The invention relates to a catalytic reactor suited for exothermal reactions with a radial process fluid flow and process fluid flow guides which ensures an extended fluid flow path and higher flow velocity and thereby enhanced cooling of the catalyst bed in the reactor.
US10589240B2	Method and apparatus for blending viscous fluids and additives A blender for blending viscous material and additive material by vortex action includes an upper section and a lower section. The upper section has a receiving portion, a viscous material inlet that is in fluid communication with the receiving portion, and an additive inlet that is in fluid communication with the receiving portion. The lower section is attached to and disposed below the upper section, said includes a blending portion that is in fluid communication with the receiving portion of the upper section. The blending portion is shaped so as to facilitate the blending of the additive material entering the receiving portion through the additive inlet with the viscous material entering the receiving portion through the viscous material inlet. The blender includes an outlet for blended material that is in fluid communication with the blending portion of the lower section. A method of blending additive materials with asphalt cement employs a blender having no moving parts that is adapted to blend asphalt cement and additive materials by vortex action.
US10589239B2	Fluid mixing in a disposable fluid processing system High accuracy mixing of fluids in a disposable fluid processing system with at least two pumps is provided by a method where a calibration fluid volume is pumped through each pump via a flow meter at at least one calibration pump speed while registering the flow rate using data output from the flow meter, a pump calibration function is calculated from the calibration pump speed and flow rate data and two or more operation fluids are mixed to a predetermined mixture ratio and predetermined flow rate by controlling the pump speed of the respective pumps in accordance with the pump calibration functions.
US10589234B2	Wet disperser Embodiments provide a wet disperser for dispersing particulates in a mixture containing at least a dispersing medium and particulates. According to various embodiments, the wet disperser includes a through channel extending from an inflow port to an outflow port, and a mixture-passing plate having at least one passing hole defined. In the wet disperser, the through channel includes, on a downstream side of the through channel from a position provided with the mixture-passing plate, a dispersion part having a vibration body provided such that vibration causes at least a part of the vibration body to come into contact with at least a part of an opening periphery of the passing hole, and an inside surface defining the passing hole of the mixture-passing plate.
US10589233B2	Foam mixing system and methods Foam dispensing systems and methods are disclosed. Such systems and methods may include a foamed material dispenser, a dynamic mixer having a gas input, a process material input, and a foamed material output. The foamed material output may be in fluid communication with the foamed material dispenser. A pump having an output may be in fluid communication with the process material input of the dynamic mixer, and a gas injection valve may be in fluid communication with the gas input of the dynamic mixer. A gas pressure regulator may be coupled between the pressurized gas supply and the gas injection valve, and a gas injection cycle timer may be operatively connected to the gas injection valve, the gas injection cycle timer causing the gas injection valve to pulse open and closed to send pulses of pressurized gas into the dynamic mixer through the gas input.
US10589232B2	Forward osmosis membrane and forward osmosis treatment system A forward osmosis membrane characterized in that a thin membrane layer having the performance of a semi-permeable membrane is laminated on a polyketone support layer.
US10589222B2	Urea water agitation control device A urea water agitation control device has an agitation control portion and a temperature sensor which detects a temperature of a urea water. The agitation control portion operates an agitation portion in a specified period which includes a part of a period in which the urea water temperature detected by the temperature sensor is kept at a eutectic point and the urea water radiates a latent heat of solidification.
US10589221B2	Low-emission fired heater In various aspects, systems and methods are provided for integrating molten carbonate fuel cells with a fired heater for production of electrical power while also reducing or minimizing the amount of CO2 present in the flue gas generated by the fired heater. The molten carbonate fuel cells can be integrated for use with fired heater so that at least a portion of the flue gas from fired heater flows through cathodes of the fuel cells and at least a portion of the cathode exhaust is returned to a convection section of the fired heater.
US10589219B2	Environmental control assemblies An environmental control assembly includes a housing including a base layer, a diffusor layer, and an interior space at least partially formed by the base layer and the diffusor layer. The environmental control assembly further includes a desiccant positioned within the interior space and an inlet filter that is formed from a cutout in the base layer that is covered by the diffusor layer.
US10589214B2	CO2 mass transfer enhancement of aqueous amine solvents by particle additives The present invention relates to methods for improving carbon capture by providing particles within an amine solvent. The particles provide for increased turbulence at the interface between the counter-flowing gas and solvent, which allows for increased amine and carbamate salt diffusion between the liquid film and bulk.
US10589212B2	Ammonia-adding system for ammonia-based desulfurization device Ammonia-adding apparatus and methods for ammonia-based desulfurization use multi-stage control, calculate a theoretical amount of ammonia based on gas amounts provided by an inlet continuous emission monitoring system (CEMS) and an outlet CEMS of the ammonia-based desulfurization device or associated gas amounts, a SO2 concentration provided by the inlet CEMS, and a predetermined SO2 concentration of the outlet CEMS. The apparatus and methods calculate a corrected theoretical amount of ammonia using half of the ratio of the actual amount of added ammonia to the actual amount of removed sulfur dioxide as a correction coefficient for the theoretical amount of ammonia; add an ammonia absorbent equivalent to the corrected theoretical amount of ammonia to the ammonia-based desulfurization device through an ammonia metering means and an ammonia control valve, and automatically control the actual ammonia flow rate based on the actual SO2 concentration and a change trend provided by the outlet CEMS.
US10589202B2	Component for a fluid filter, and fluid filter The present invention relates to a fuel filter component containing a heating device for heating a fluid; a detection device for detecting a level of a further fluid, located in a reservoir; and an outlet conduit for the further fluid. The component is a one-piece component, in particular the heating device, detection device, and outlet conduit are embodied. The present invention further relates to a fluid filter, in particular a fuel filter, having such a component.
US10589199B2	Gravity-fed water purification system A device for providing purified water from a silt-laden source water having an upper canister, a lower canister, and a filter mounted in the upper canister; wherein the upper canister and the lower canister are fluidly connected via the filter; wherein pre-filtered water is collected in the upper canister and purified water is collected in the lower canister; wherein a pre-filter is fluidly connected between the source water and the upper canister; wherein the pre-filter has a pre-filter canister having an inlet for source water and an outlet for pre-filtered water; wherein the pre-filter canister contains a fine depth filter and a felt filter.
US10589197B2	Microcarrier filter bag assemblies and methods of use A filter bag assembly includes a flexible bag bounding a compartment that is configured to hold a fluid. An inlet port and an outlet port are each secured to the flexible bag so as to communicate with the compartment. A porous filter sheet is disposed within the compartment of the flexible bag so that fluid entering the compartment through the inlet port must pass through the filter sheet before exiting the compartment through the outlet port. A first retention seal secures the porous filter sheet to a portion of the flexible bag within the compartment, the first retention seal having an outer perimeter edge that forms an annular continuous loop.
US10589194B2	Filtration module and method for producing same A filtration module (1) has a filter unit (2) with at least one filter element (6) arranged between first and second plates (4, 5). The filter element (6) has at least one layer of filter material (9, 10) sealed off at a periphery by an edge seal (12). The plates (4, 5) are pressed against each other by a resilient bracketing profile (3) that engages around the plates (4, 5) at their opposite side surfaces (21, 22, 23, 24). The bracketing profile (3) has a base (13) that curves inward transversely to the longitudinal direction (14) of the plates (4, 5) and that is delimited by lateral brackets (16, 17) that are bent inward at their free ends (18, 19) to engage laterally around a surface (20) of the filter element (6) facing away from the base (13). A method also is provided for producing a filtration module.
US10589191B2	Method for separating substance accommodated in vessel Provided is a method for separating a substance accommodated in a vessel-shaped structure comprising subjecting a vessel-shaped structure 1, which includes a vessel portion a, a vessel portion b, and a self-fusing material X connecting the both vessel portions, and which accommodates a substance selected from the group consisting of a liquid, a solid a gas, and a dispersion system, to the steps: (i) pulling the vessel portion a and the vessel, portion b away from each other to extend the self-fusing material X; (ii) fusing the extended self-fusing material X together between the vessel portion a and the vessel portion b to separate the accommodated substance; and (iii) cutting a fused part of the self-fusing material X to separate the vessel-shaped structure 1 into a separated structure.
US10589189B2	Solid/liquid separation apparatus, and method for same The solid-liquid separator that uses the substance A capable of dissolving water and oil, and performs dehydration and deoiling from an object to be treated by bringing a mixture of water and a solid, oil and a solid, or water, oil and a solid that is an object to be treated, and the substance A in a liquid state into contact with each other, and subsequently evaporating the substance A, includes a substance B that circulates while causing change of state in a closed system, a compressor that compresses the substance B, a first heat exchanger that exchanges condensation heat of the substance B and evaporation heat of the substance A, an expansion valve that decompresses the substance B which is condensed, and a second heat exchanger that exchanges evaporation heat of the substance B and condensation heat of the substance A.
US10589186B2	Clip for securing vessel internals and method of assembly A clip assembly for holding down a member in a vessel comprising a clip comprising a first panel comprising a tab extending from the first panel and a protrusion extending from the first panel, and a second panel integral with and normal to the first panel for engaging the member. A wall in the vessel comprises a cut-out adapted to receive the tab and a recess disposed laterally to the cut-out and adapted to receive the protrusion upon inserting the tab into the cut-out and sliding the tab in the cut-out laterally with respect to the recess. The subject matter also pertains to the clip itself and the method of use.
US10589183B2	Sequentially operated modules Method, modules and a system formed by connecting the modules for controlling payloads are disclosed. An activation signal is propagated in the system from a module to the modules connected to it. Upon receiving an activation signal, the module (after a pre-set or random delay) activates a payload associated with it, and transmits the activation signal (after another pre-set or random delay) to one or more modules connected to it. The system is initiated by a master module including a user activated switch producing the activation signal. The activation signal can be propagated in the system in one direction from the master to the last module, or carried bi-directionally allowing two way propagation, using a module which revert the direction of the activation signal propagation direction. A module may be individually powered by an internal power source such as a battery, or connected to external power source such as AC power. The system may use remote powering wherein few or all of the modules are powered from the same power source connected to the system in a single point. The power may be carried over dedicated wires or concurrently with the conductors carrying the activation signal. The payload may be a visual or an audible signaling device, and can be integrated within a module or external to it. The payload may be powered by a module or using a dedicated power source, and can involve randomness associated with its activation such as the delay, payload control or payload activation.
US10589181B2	Car with rotatably mounted wheel axle for a fairground ride and method for controlling a rotatably mounted wheel axle of such a car The invention is a car for a fairground ride with at least one axle arranged on a rotatable carrier structure and a coupling element for coupling a further car, wherein the coupling element is movably mounted and connected to the carrier structure via a mechanical operative connection so that a movement of the coupling element leads to a rotation of the carrier structure and of the wheel axle arranged thereon and a rotation of the rotatable carrier structure leads to a movement of the coupling element, and a method for controlling the rotation of a mounted carrier structure of a wheel axle of a car of a fairground ride with a coupling element for a further car, wherein a position change of the relative position of the car in relation to another is translated into a position change of the coupling element.
US10589180B2	Method and apparatus for providing online shooting game The present disclosure relates to providing an online shooting game by a game server communicatively connected to a player terminal. The player terminal may display a virtual online shooting game environment based on information received from the game server. Providing an online shooting game may include: selecting a basic identification range within a virtual online shooting game environment displayed on the player terminal; detecting one or more enemy characters that are within the basic identification range; determining one of the detected one or more enemy characters as an automatic tracking object; and allowing an aiming point to automatically track movement of the automatic tracking object within the basic identification range.
US10589178B2	Method and apparatus for providing a computer implemented game A display of a computer device displays a plurality of different levels of a computer implemented game and a first reward item. The first reward item is associated with a first level which has yet to be completed. At least one processor determines that a player has reached the first level and in response thereto, the display displays a second reward item. The second reward time associated with a second different level of said computer implemented game which has yet to be completed and a time limit. If the player reaches the second level within said time limit, a game reward is provided.
US10589172B1	Embedding metadata in rendered content Useful metadata can be embedded directly into dynamically rendered content in a way that is minimally perceptible to a viewer. Objects to be rendered for an application, such as backgrounds and gameplay elements for a gaming application, can have their appearance modified in order to embed specified metadata. The modifications can impact the color, patterns, configuration, or other aspects of the objects. The metadata can include any data useful for identifying a state, context, or configuration for the presentation of content, such as the state of a game at the time of rendering, as well as information about the player or device corresponding to a device-specific rendering of the content. A video segment including a representation of the rendered content can be analyzed to quickly identify and extract the metadata, which can help to quickly obtain the information needed to perform certain tasks, such as debugging or issue spotting.
US10589168B1	Fluid film game toy A fluid film game toy includes a racket including an open frame, a handle connected to the outer perimeter of the open frame and a film-forming face located on the inner perimeter of the open frame for creating a fluid film within the open frame, and a game component to be placed on the fluid film and moved on the fluid film by the player who manipulates the handle to move and/or tilt the open frame.
US10589165B2	Snow sport equipment waxing device and method Automated systems, methods and devices for refinishing surfaces on equipment (such as skis and snowboards), engaging the equipment and retracting ski brake arms are disclosed. The disclosure includes applying wax on at least skis and snowboards and may provide kiosks where skiers and boarders can deposit their equipment in a track and have appropriate wax for current snow conditions applied to the equipment.
US10589161B2	System and method for monitoring performance characteristics associated with user activities involving swinging instruments Exemplary embodiments of the present disclosure are directed to various components of a system for monitoring and/or tracking a user's performance during an activity involving an instrument that is swung. Exemplary embodiments can include a sensor module configured to be secured to and/or embedded within the instrument. The sensor module can detect a swing event and/or an impact between the instrument and an object and can generate pressures waves that propagate through air. The pressure waves can include information or represent information about a use of the instrument and can be detected by an electronic device associated with the user, which can display the information, process the information, and/or transmit the information to a remote system. The pressure waves can be modulated to encode information within the pressure waves.
US10589155B2	Golf club head Disclosed herein is a golf club head. A face portion of the golf club head has a bulge radius between 190 mm and 600 mm and a roll radius between 100 mm and 600 mm. The golf club head further comprises a first wall, protruding uprightly from the sole portion, extending lengthwise in a heel-to-toe direction. The golf club head additionally comprises a stiffener located within the interior cavity of the body and interposed between the interior surface of the face portion and the first wall. The stiffener is made of a second material having a second modulus of elasticity less than the first modulus of elasticity. A coefficient of restitution (COR) of the golf club head is at least 0.78. A characteristic time (CT) of the golf club head at a center of the face portion is no more than 257 microseconds.
US10589152B2	Apparatus for collecting and storing tennis balls A ball collecting apparatus is provided that employs a human-powered ball transport system that moves balls from a collecting surface to a location above the collection surface. The ball collecting apparatus employs no motors or other artificially powered devices to retrieve and transfer balls, which makes it light and easy to maneuver. The ball collecting apparatus is primarily contemplated for use of picking up tennis balls, but other balls of various sizes may be accommodated by the apparatus, as it is scalable.
US10589150B2	Automated prescription of activity based on physical activity data The invention provides a method of monitoring an activity session comprising receiving activity data indicative of at least one activity performed during the activity session, the activity data comprising a plurality of measurements associated to a plurality of parameters monitored during the activity session; a processor comparing at least some of the received measurements associated to at least two of the parameters with at least one set of a plurality of sets of measurements stored on a tangible computer readable medium; and a processor generating a training plan based at least partly on a comparison between the received measurements and the stored measurements. Other aspects of the invention provide an exercise coaching system.
US10589147B1	Office treadmill An office treadmill allows an office worker to walk while working without compromising the quality and speed of job performance. It consists of a walking device which is easily converted into an office chair. The conversion from treadmill into office chair and vice versa takes about a minute and is not a physically or intellectually challenging task. The office worker can perform the full range of office duties while walking due to the “Stop” element of the Office Treadmill package.
US10589143B1	Weight lifting support system A weight lifting system includes a harness having a body with a thickness, the body having a contoured shape to fit around a shoulder of a user; an opening extending through the thickness of the body and sufficiently sized to receive a head of the user therethrough; and a cradle extending from a back surface of the harness and contoured to receive a weight bar within a channel.
US10589140B2	Exercise device An apparatus for suspension training may include at least one supporting strap and at least one moveable handle, wherein the moveable handle further includes a first and second end and the first and second ends further include an engageable locking means and the engageable locking means are in communication with the support strap. In this way the position of the moveable handles may be easily adjusted, increasing the convenience of moving the moveable handles to undertake different exercises using the training or exercise device.
US10589139B2	Modular valve assembly A wet piping system modular valve assembly includes a single piece valve body with a check valve within the valve body. The check valve is movable between a closed position and an open position according to a pressure differential across the check valve. A drain valve is removably mounted to the valve body and fluidly connected with the valve body downstream of the check valve. A mechanically independent flow detection switch is removably mounted to the valve body and fluidly connected with the valve body upstream of the drain valve.
US10589138B2	Enhanced foam spray pattern device One or more techniques and/or systems are disclosed for a foam fluid dispensing device that allows for quick and easy adjustment between a straight stream and dispersed stream. A user can quickly adjust between various stream patterns using a common motion in nozzle operation. An example device can comprise a nozzle comprising a nozzle body and an inlet configured to receive a flow of fluid, with a nozzle stem centrally disposed in the nozzle and fixedly engaged with the nozzle body. The device can also comprise a foam tube configured to receive and dispense at least a portion of the flow of fluid from the nozzle, with a foam tube coupler fixedly engaged with the foam tube. The foam tube coupler can be configured to operably couple with the nozzle stem.
US10589135B2	Hydraulic implement A hydraulic implement (1) for portable use includes a hydraulic pump (2), a pump housing (10), a hydraulic cylinder (3) with a piston rod (11), a hydraulic tank (4), hydraulic lines, a compensating device, a manually operable hydraulic control valve (8), a rechargeable battery (9) which is accommodated on the implement (1), and two tool halves (16, 17) that are connected to the piston rod (11) via pivoting arms (12, 13). Each tool half (16, 17) has a wall section (20, 21) that extends perpendicularly to the extension of the longitudinal axis of the piston rod (11). When the tool halves are closed, both wall sections (20, 21) together form a flattened end region (24) that runs perpendicularly to the extension of the longitudinal axis of the piston rod (11).
US10589133B2	Cosmetic preparation and use thereof A cosmetic preparation characterized by excellent adhesion at the place of application, comprises at least one silsesquioxane wax.
US10589130B2	Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
US10589129B2	Therapeutic ultrasound with reduced interference from microbubbles Various approaches for reducing microbubble interference with ultrasound waves transmitted from multiple transducer elements and traversing tissue onto a target region include measuring microbubbles in high-throughput areas of ultrasound exposure and reducing the amount of microbubbles using the ultrasound waves.
US10589126B2	System for detecting stent slippage, method for detecting stent slippage The invention provides a method for locating radioactive material implanted in a living body, the method having the steps of implanting a stent into the body, the stent containing the radioactive material; imaging the body to determine a first position of the stent relative to remote points on the body; determining a second position of the stent at a second time later than the time of the implanting step; and measuring the distance between said first position and said second position. Also provided is a system for determining movement of a radiation source implanted in a living body, the device having a radiographic film overlaying a region of the body so as to oppose the radiation source, whereby the film is positioned relative to a reference point on the body; a grid disposed between the film and the body; and a radio-opaque substrate overlaying the film.
US10589125B2	Bolus and method for producing same Provided is a bolus formed of a hydrogel, wherein the hydrogel includes water, a polymer, and a mineral, and wherein the bolus is applied to a patient who receives a radiation therapy.
US10589123B2	Systems, methods and compositions for optical stimulation of target cells Stimulation of target cells using light, e.g., in vitro, is implemented using a variety of methods and devices. One example involves a vector for delivering a light-activated NpHR-based molecule comprising a nucleic acid sequence that codes for light-activated NpHR-based molecule and a promoter. Either a high expression of the molecule manifests a toxicity level that is less than about 75%, or the light-activated NpHR-based proteins are expressed using at least two NpHR-based molecular variants. Each of the variants characterized in being useful for expressing a light-activated NpHR-based molecule that responds to light by producing an inhibitory current to dissuade depolarization of the neuron. Other aspects and embodiments are directed to systems, methods, kits, compositions of matter and molecules for ion pumps or for controlling inhibitory currents in a cell (e.g., in in vivo and in vitro environments).
US10589120B1	High-intensity laser therapy method and apparatus A method of laser irradiation for alleviating the physical symptoms associated with acute or chronic inflammatory conditions, which can include directing a laser beam from a laser unit in a continuous wave operation having a wavelength of approximately 1275 nm and a power output level in the range of from one (1) Watt up to and including 75 Watts on an inflamed area that is to be treated, such that the laser beam penetrates the inflamed area in the range of from 0.1 cm to 30 cm. In addition, the laser beam from the laser unit can be configured to activate intracellular photoreceptors, thereby initiating a cascade of secondary cellular metabolic effects and normalizing cellular activity towards homeostasis.
US10589115B2	Inner ear therapy device and method for operating inner ear therapy device An inner ear therapy device includes a magnetic field generation unit configured to generate a magnetic field toward the inner ear of a user, multiple light sources configured to irradiate multiple lights having different wavelengths toward the inner ear, and a control unit configured to control operations of the magnetic field generation unit and the multiple light sources.
US10589111B2	High gain passive repeater antenna for medical device cabinets A cabinet capable of attenuating or blocking wireless signals contains, a medical device, such as an AED, an internal directional antenna mounted to an internal surface of the cabinet, an external omnidirectional antenna mounted to an external surface of the cabinet, and an electrical connection between the internal directional antenna and the external omnidirectional antenna. The internal and external antennas are configured to transmit wireless signals at particular frequencies and to receive wireless signals at the particular frequencies. The internal antenna is a high gain directional antenna, and the external antenna is a lower gain omnidirectional antenna.
US10589110B2	Wearable therapeutic device A wearable monitoring device is provided. The wearable monitoring device includes a garment to hold an electrode, be worn about a subject, and include an orientation circuit. The monitoring device also includes a control unit coupled to the orientation circuit capable of measuring at least one parameter associated with the orientation circuit and determine whether the electrode is positioned in the garment with the conductive surface oriented towards the subject based on the at least one parameter.
US10589100B2	Method and device for pacing latency based multi-point pacing Methods and devices are is provided for controlling a pacing therapy utilizing left ventricular multi-point pacing (MPP). The method and device provide electrodes configured to be located proximate to an atrial (A) site, a right ventricular (RV) site and multiple left ventricular (LV) sites of the heart. The method and device utilizes one or more processors. The processors determine atrial-ventricular conduction delays (AVCD) between the A site and multiple corresponding LV sites and determines pacing latencies at the LV sites. The processors adjusts the AVCDs, based on the pacing latency at the corresponding LV sites, to form atrial-ventricular latency adjusted (ARPL) conduction delays for the corresponding LV sites, calculates interventricular pacing (VV) delays for combinations of the LV sites based on the corresponding ARPL conduction delays and manages pacing therapy, that utilizes left ventricular MPP, based on the VV delays for the corresponding LV sites.
US10589095B2	Device for treating disorders of secreting gland in eyelid Disclosed is a device for treating disorders of a secreting gland in an eyelid. The device includes an eyeball protection cap for covering an eyeball of a patient to protect the eyeball, and a support body for fixing the eyeball protection cap and enabling an eyelid of the patient to be located between the eyeball protection cap and the support body in order to support the eyelid in the state of being in contact with the eyelid, wherein the eyeball protection cap is configured such that the inner surface of the eyeball protection cap covers the eyeball in order to protect the eyeball and the outer surface of the eyeball protection cap contacts the inner surface of the eyelid, which is located between the eyeball protection cap and the support body, in order to provide electrical stimulation to a secreting gland in the eyelid such that a secretion is smoothly secreted from the secreting gland.
US10589092B2	Methods for enhancing and modulating reversible and irreversible electroporation lesions by manipulating pulse waveforms A ratio of reversible electroporation and irreversible electroporation may be controlled by selecting a symmetric waveform or asymmetric waveform to either minimize or enhance irreversible effects on cells in the target tissue. Combined reversible and irreversible electroporation includes inserting one or more therapeutic electrodes into a target tissue, introducing an electroporation compound into the target tissue, selecting a pulse waveform that is either 1) asymmetric bipolar that has positive and negative pulses with different durations, or 2) symmetric bipolar that has positive and negative pulses with the same duration, and delivering to the target tissue a series of electrical pulses having the selected pulse waveform.
US10589091B2	Static electricity generator and methods thereof The present invention provides a portable handheld static-electricity generator and a method thereof for alleviating pain in at least one portion of patient's body, comprising: a movable brush, a polymer assembly comprising a rubbing-surface portion upon which the brush rubs and an automatically-operated mechanical unit. The polymer assembly having affinity to a defined charge such that when the movable brush rubs the rubbing-surface of the polymer assembly for a predefined time a static electricity is generated.
US10589089B2	Systems and methods for delivering neuroregenerative therapy Systems, devices and methods are disclosed for the treatment of injured peripheral nerves or other tissue using electrical stimulation. The systems can be used either in intraoperative or peri-operative settings and incorporate the use of either a plurality of monopolar electrodes with a patch used as return or a plurality of bipolar electrodes such as a cuff. The systems can provide hands-free delivery of electrical stimulation therapy over a predetermined set of time.
US10589088B2	Apparatus for application of a pulsed radio frequency therapy in a vascular system or another cavity or tissue of the human or animal body The invention relates to an apparatus for application of a pulsed radio frequency therapy in a vascular system or another cavity or tissue of the human or animal body comprising a catheter with at least one electrode disposed thereon for insertion into the vascular system or another cavity or the tissue of the human or animal body; a probe with at least one further electrode disposed thereon, wherein the probe is insertable via the catheter into the vascular system or the other cavity or the tissue of the human or animal body; and a generator electrically connected with the electrodes for generating a pulsed electro-magnetic field between the electrodes.
US10589087B2	Systems and methods for altering brain and body functions and for treating conditions and diseases of the same The present invention relates to systems and methods for management of brain and body functions and sensory perception. For example, the present invention provides systems and methods of sensory substitution and sensory enhancement (augmentation) as well as motor control enhancement. The present invention also provides systems and methods of treating diseases and conditions, as well as providing enhanced physical and mental health and performance through sensory substitution, sensory enhancement, and related effects.
US10589085B2	Lead for brain applications A lead for brain applications, comprises at least one distal section and at least one electrode, whereby the at least one electrode is arranged in the distal section and whereby the at least one electrode is connected directly and/or indirectly with at least one first connecting trace and at least one second connecting trace. Furthermore, in some examples, the lead relates to a deep brain stimulation (DBS) system.
US10589084B2	Aortopulmonary electrical stimulator-pressure transducer In an embodiment herein, an aortopulmonary stimulation device is provided including a first electrode for placement on or in the aorta, and a second electrode for placement on or in the pulmonary artery. The embodiment includes a control unit associated with the first and second electrodes for delivering electrical stimulation to the first and second electrodes, wherein the stimulation is delivered to both the first electrode and the second electrode, or to the first electrode or the second electrode to reduce afterload.
US10589081B2	Peripheral IV catheter with Bi-valve secure system The Purpose of our devise “Peripheral Intravenous Catheter With an internal Bi-Valvular Secure System” is to Avoid Back-flow spilling of blood or any other biological substance during the insertion of a catheter. Not only the Bi-valvular secure system is adaptable for the use in intravenous or arterial catheters but it can also be adapted to any type of Medical system catheters available in Medical practice due to its unique design, and without the need of changing the complete physical structure of the catheter. The present invention is for Medical field use and it provides a much more sterile and secure approach in reducing the risk of exposure to biological substances while at the same time reducing the risk of contamination to both the patient and the health care provider.For Purpose of of describing the full operating system of our devise, we have to reiterate that its function is based on the concept of keeping a sterilized access to any Medical System Catheter by avoiding back-flow spilling of any biological substance that could increase the risk of exposure and contamination.
US10589074B2	Magneto-resistive sensor tool set for hydrocephalus valve A locator as part of a toolkit for locating an implanted valve. The locator is used in concert with an indicator that nests therein. The locator has a lower ring with a contact surface, contacting a patient, a key positioning the nested indicator to prevent rotation, and a lower ring joint opposite the contact surface. Also included is an upper ring with an upper ring joint rotatingly interfacing with the lower ring joint, a flow direction identifier, and a flow setting identifier. Further, the upper and the lower rings rotate relative to each other, and the lower ring is floor-less.
US10589071B2	Multiple function balloon catheter A dual double balloon catheter includes a catheter having a proximal end portion, a central portion and a distal end portion. The catheter includes a plurality of lumens within the catheter extending from the proximal end portion, and a plurality of inflatable balloons positioned in the central portion and/or the distal end portion, and the balloons being communicatively connected with a corresponding one of the plurality of lumens to selectively inflate/deflate the corresponding inflatable balloon, wherein one or more of inflatable balloons further includes a second one of the plurality lumens associated with a corresponding inner wall of a corresponding inflatable balloon and adapted to receive a radioactive dose or a therapeutic agent for a treatment. The plurality of balloons can have varying sizes in relation to each other and also include lumens within or associated with the inner walls of the balloons to deliver a treatment.
US10589070B2	Micro-needle bladder balloon Devices and methods for delivering treatment fluids or particulates such as, stem cells, drugs, Botox and like, to an inner lining of a bladder for treatment of urinary tract disorders, including over active bladder. A balloon delivery system can include an inflation balloon having a plurality of micro-needles configured to pierce and otherwise puncture an inner bladder wall so as to deliver the treatment fluid to bladder tissue. The treatment fluid can be directly injected into the bladder tissue using the micro needles. Alternatively, the micro needles can be fabricated of bioabsorbable or bioresorbable materials such that the micro needles can remain embedded within the bladder tissue to deliver the treatment fluid or particulate.
US10589066B2	Counting apparatus for use in interventional procedures An apparatus is for use in connection with an implement for being inserted into a vascular space. The apparatus includes a body having a passage adapted for receiving the implement. A counter is provided for counting the amount the implement moves through the passage of the body. A kit may include a first counter adapted for use with a first device having a first diameter for being inserted into the vasculature, and a second counter adapted for use with a second device having a second diameter for being inserted into the vasculature. Related methods are also disclosed.
US10589062B2	Adjustable curved medical catheter and assembling method thereof An adjustable curved medical device includes a catheter, a handle, and a traction wire provided in the catheter. The distal end of the traction wire is connected to the distal end of the catheter. A retainer device is provided in the handle, and includes a rotating member and a body having a receiving groove for receiving the rotating member, and a guiding hole extending through the outer wall of the body to the receiving groove. A slot formed between the rotating member and the inner wall of the body is smaller than the diameter of the traction wire. The proximal end of the traction wire extends through the guiding hole and engages in the slot.
US10589060B2	Extrusion with preferential bend axis A catheter is made by coextruding first and second molten polymers, wherein the second molten polymer forms a flexible inner core and the first molten polymer forms exactly two bands on opposite sides of the inner core. The inner core is braided, and a third molten polymer extruded onto the braid to form a flexible jacket that encloses the braid, the bands and the inner core. The bands are more rigid than the inner core, and they provide preferential in-plane bending.
US10589059B2	Insertion device with protection against reuse An insertion device (110) for inserting an analyte sensor (114) into a body tissue is proposed. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for linearly driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The actuator (132) comprises at least one actuator arm (136, 138) which is pivotable about at least one axle (140) in order to actuate the drive mechanism (124). The insertion device (110) further comprises at least one protection against reuse including at least one locking mechanism (178). The locking mechanism (178) is adapted to at least partially prevent a back-pivoting of the actuator arm (136, 138) in a direction reversing the actuation direction once the actuator arm (136, 138) has been pivoted by at least one threshold angle.
US10589053B2	Active valve for ventilators A method for controlling a ventilator includes the steps of providing an inhalation pressure limit, determining when a pressure in a connection to a patient circuit is greater than the inhalation pressure limit, and opening the valve when the pressure is greater than the inhalation pressure limit. An associated computer readable medium for controlling the method is also described.
US10589048B2	Modular back strap for patient interface device A back strap for a patient interface device having a headgear component including a first strap member and a second strap member attached to the first strap member and structured to wraparound a back of the patient's head. The back strap member includes a first portion having a first attachment mechanism structured to couple the first portion to the second strap member, a connecting portion extending from the first portion, and a second portion having a second attachment mechanism structured to couple the second portion to at least one of the first strap member, a patient sealing assembly, or skin, hair, neck or clothing of the patient in a manner wherein the back strap member is configured to hold the second strap member and prevent it from riding up on a head of the patient during use.
US10589043B2	Oscillating positive expiratory pressure device A respiratory treatment device comprising at least one chamber, a chamber inlet configured to receive air into the at least one chamber, at least one chamber outlet configured to permit air to exit the at least one chamber, and a flow path defined between the chamber inlet and the at least one chamber outlet. A restrictor member positioned in the flow path is moveable between a closed position, where a flow of air along the flow path is restricted, and an open position, where the flow of air along the flow path is less restricted. A vane in fluid communication with the flow path is operatively connected to the restrictor member and is configured to reciprocate between a first position and a second position in response to the flow of air along the flow path.
US10589041B2	Inhaler An inhaler comprising a reservoir of an inhalable composition. A valve element moved by a flexible diaphragm and biased into a position in which it closes a composition flow path from a reservoir. A first air flow path is partly defined by one side of the diaphragm and a second air flow path is partly defined by the opposite side of the diaphragm. Each flow path has an outlet opening at an outlet end and the second flow path has an inlet upstream of the outlet end. The air flow paths are arranged such that suction at the outlet end causes a reduction in pressure in the first air flow path relative to the pressure in the second air flow path creating a pressure differential across the diaphragm that moves the valve element against the biasing force to open the composition flow path.
US10589031B2	Flexible medicament injector and method of use An injector device and method for use, and particularly a veterinary injector, is disclosed herein. One aspect of the present technology, for example, is directed toward a veterinary injector including a flexible container configured to house a medicament, a plunger configured to be slidably received within a lumen of the container, a needle, and a stabilizer at the distal portion of the container and configured to be grasped by a user. The stabilizer can include a first flap extending away from the hub in a first direction, a second flap extending away from the hub in a second direction, and a third flap extending away from the hub in a third direction.
US10589030B2	Device for attachment to a portable liquid injection device The invention refers to a device for attachment to a portable liquid injection device, wherein said device is designed to enclose the drug reservoir of the injection device completely. Further, said device has at least two flat conductive electrodes enabling an electrical field to be applied across the entire volume of the drug reservoir of the injection device. In particular, the portable liquid injection device is a so-called insulin pen, i.e. a portable liquid injection device which is used to inject insulin for the treatment of diabetes. The inventive device preferably is in the form of a cap, in particular in the form of a cap of an insulin pen.
US10589023B2	Patch-like infusion device A system and method for a patch-like, self-contained substance infusion device which can be attached to a skin surface via an adhesive contact surface. A push button activation assembly can then be used to remove an interlock, allowing a disk or Belleville spring assembly to apply an essentially even and constant pressure to the contents of a fluid reservoir assembly. This allows the release of one or more spring-loaded patient needles into the skin surface, and establishes a fluid communication path between the patient needles and the pressurized fluid reservoir contents thereby delivering an infusion into the skin. The push button activation assembly further allows the release of one or more improved safety mechanisms after use.
US10589017B2	Package for medical product A package for a multi-component medical device is disclosed. The package includes a bottom portion with cavities providing individual access to different components of the medical device, thereby enabling a user to remove components from the package in any order without disturbing the remaining component or components. The package also includes a barrier affixed to the bottom portion for sealing the package.
US10589016B2	Treatment system with infusion apparatus pressure priming A system or method includes an infusion apparatus controllable to provide a fluid flow from a replaceable fluid dispenser at a set flow rate. The infusion apparatus may be commanded to operate on a replacement fluid dispenser to provide one or more boluses of the plurality of boluses into an infusion line. If the infusion apparatus is not being prevented (e.g., by system back pressure or frictional forces) from delivering the one or more boluses then the infusion apparatus may be controlled to deliver a plurality of boluses at a set flow rate. If the infusion apparatus is being prevented from delivering the one or more boluses then the infusion apparatus may be controlled to pressure prime the replacement fluid dispenser by accelerating one or more commands to the infusion apparatus to deliver one or more boluses into the infusion line.
US10589013B2	Prosthetic rib with integrated percutaneous connector for ventricular assist devices A mechanical circulatory support system includes an implantable blood pump, an implantable prosthetic rib assembly, and an implantable drive cable. The prosthetic rib assembly includes a prosthetic rib segment and a percutaneous electrical connector mounted to the prosthetic rib segment. The prosthetic rib segment is configured to be mounted to a patient's rib in place of a resected segment of the patient's rib. The electrical connector includes a skin interface portion configured to interface with an edge of a skin aperture through the patient's skin. The electrical connector is configured to expose a connection port of the electrical connector via the skin aperture. The implantable power cable is connected with or configured to be connected with each of the blood pump and the percutaneous electrical connector for transferring electric power received by the percutaneous electrical connector to the blood pump.
US10589007B2	Fluid collection canister with integrated moisture trap A moisture trap for removing liquid from a fluid drawn from a tissue site treated with reduced pressure and systems and methods for using the same are described. The moisture trap may include a barrier adapted to be fluidly coupled to and define an indirect fluid path between a fluid reservoir and a reduced-pressure source. The barrier may have a hydrophilic surface. The moisture trap also may include a sump adapted to receive condensation from the barrier.
US10589001B2	Pharmaceutical formulation for use in spinal fusion A pharmaceutical formulation for use in a spinal fusion method, comprising a composition for forming a matrix, a kit comprising the composition, a pharmaceutical product obtainable from the pharmaceutical formulation, and an interbody spinal fusion cage containing the pharmaceutical formulation or the pharmaceutical product are described herein. The composition comprises at least a first matrix material precursor component and a second matrix material precursor component that are able to crosslink to form the matrix under appropriate conditions, a bioactive factor that is biologically active for stimulating bone formation between two vertebrae and for effecting or supporting spinal fusion. The bioactive factor is PTH, optionally a PTH fusion peptide. The bioactive factor is releasably incorporated in the matrix upon crosslinking of the matrix material precursor components.
US10588998B2	Adhesive compositions and related methods Adhesive compositions and patches, and associated systems, kits, and methods, are generally described. Certain of the adhesive compositions and patches can be used to treat tissues (e.g., in hemostatic or other tissue treatment applications), according to certain embodiments.
US10588997B2	Polymer nanofiber scaffolds and uses thereof A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers.
US10588992B2	Aerosol device An aerosol device having a bowl with a bottom defining a drain, and a side wall extending from the bottom to a rim. A nozzle is disposed within the bowl. The nozzle defines a chamber and an outlet orifice directed toward the side wall of the bowl. The aerosol device includes a liquid container fluidly coupled to the nozzle via a first conduit having an outlet tip disposed within the chamber of the nozzle and a second conduit connecting a source of pressurized gas to the chamber of the nozzle. The outlet tip is in the form of a tube defining elongated slots communicating from inside the tube to outside the tube, the slots each having a width defined between two parallel tube surfaces. The aerosol device generates submicron liquid droplets, and is suitable for disinfecting porous articles in an enclosed volume.
US10588991B1	Disinfectant pouch with fluid control A disinfectant device including a pouch, the pouch including a first layer of material coupled to a second layer of material and defining a compartment therebetween. At least one dry reactant is retained within the compartment, the at least one dry reactant producing chlorine dioxide gas when exposed to water. A wick is at least partially disposed within the compartment. At least one from the group consisting of the first layer of material and the second layer of material define an array of ports along a periphery of the pouch and an array of fluid conduits, the array of fluid conduits being proximal to the array of ports, offset from the array of ports, in fluid communication with the wick, the compartment, and the array of ports.
US10588990B2	System for handling sterilization of thin body flexible containers (pouch) A system handles the sterilization of thin-body, pouch-type, flexible containers (1) and provides for applying sacrificial closures (200) to the pouches. The system loads the provisional closed pouches to be sterilized on a transport device (300) for collective transport, to perform the sterilization of the transport device (300) carrying the provisional closed pouches. The system separates in a sterile chamber, the sacrificial closures (200) from the pouches, performing filling and applying an inviolable cap (100).
US10588989B2	Sanitized animal bedding material and process The present invention provides compositions and methods for sanitization or sterilization of, or reduction or elimination of microbes from, PFR material, in particular material for use as an animal bedding. In another aspect, the invention provides sanitized or sterilized material, and especially animal bedding material, prepared using the described compositions and methods.
US10588988B2	Methods and devices for preparation of ultrasound contrast agents Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.
US10588987B2	Compositions and methods for use in medical diagnosis The present invention relates to compositions and methods for use in medical diagnosis and patient monitoring. It more particularly relates to a biocompatible gel comprising nanoparticles and/or nanoparticle aggregates, wherein: i) the nanoparticles and/or nanoparticles of said aggregate comprise an inorganic material comprising at least one metal element having an atomic number Z of at least 25, each of said nanoparticles and nanoparticle aggregates being covered with a biocompatible coating; ii) the nanoparticles' and/or nanoparticle aggregates' concentration is of about or less than 0.5% (w/w); and iii) the apparent viscosity at 2 s−1 of the gel comprising the nanoparticles and/or nanoparticle aggregates is between about 0.1 Pa·s and about 1000 Pa·s when measured between 20° C. and 37° C. The composition of the invention typically allows the delineation and visualization of at least 40% of the target biological tissue when said tissue is observed using an X-ray imaging equipment.
US10588985B2	Compositions and methods relating to RAD6 inhibition Pharmaceutical compositions, methods of treatment of proliferative diseases and commercial packages are provided according to aspects of the present invention which relate to a first therapeutic agent coupled to a nanoparticle, wherein the first therapeutic agent is SMI #8 or SMI #9 a pharmaceutically acceptable salt, ester, amide, stereoisomer, hydrate, or derivative of either thereof. According to particular aspects, the SMI #8 or SMI #9 is conjugated to gold nanoparticles.
US10588984B2	Virus-like particle conjugates for diagnosis and treatment of tumors The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules.

1 2 3 4 5 6 7 8 9 10