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US10208335B2 |
Methods for the analysis of proximity binding assay data
Various embodiments of methods for analyzing proximity binding assay (PBA) data are disclosed. Proximity binding assays as a class of analyses offer the advantages of the sensitivity and specificity of biorecognition binding, along with the exponential signal amplification offered by a variety of oligonucleotide amplification reactions, such as the polymerase chain reaction (PCR). However, as various proximity binding assays have reaction kinetics governed by an additional step of the binding of a biorecognition probe (BRP) with a target molecule, there is a need for methods for the analysis of PBA data that are particularly suited to the unique characteristics of such data. |
US10208332B2 |
Fluidic cartridge with valve mechanism
Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system. |
US10208328B2 |
Rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and automated cell image analysis system therefor
Provided are a rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and an automated cell image analysis system therefor. The antimicrobial susceptibility test is rapidly performed based on an analysis of changes in morphology and growth pattern of a microbial cell under different concentrations of various antimicrobial agents, and this makes it possible to obtain highly reliable test results faster by six to seven times than the standard method recommended by Clinical and Laboratory Standards Institute (CLSI). |
US10208324B2 |
Recombinant microorganism for improved production of fine chemicals
The present invention relates to a recombinant nucleic acid molecule, a recombinant microorganism, to a method for producing alanine and to the use of the recombinant nucleic acid molecule or the recombinant microorganism for the fermentative production of alanine. |
US10208318B2 |
CNS gene delivery using peripheral administration of AAV vectors
The present invention relates to compositions and methods for the delivery of therapeutic proteins to the CNS using recombinant AAV vectors. More specifically, the invention relates to compositions and methods for delivering proteins into the cerebrospinal fluid of mammalian subjects through peripheral administration of AAV vectors. The invention may be used to treat various disorders of the central nervous system, including degenerative diseases and motor neuron diseases. |
US10208316B2 |
Use of UMP-CMP kinases for increasing nitrogen use efficiency and low nitrogen tolerance in plants
Provided are methods of increasing nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence encoding a polypeptide at least 80% identical to SEQ ID NO: 2560, 2557, 184, 238, 188, 154-156, 158-161, 163-183, 185-187, 189-197, 200-237, 239-264, 266-269, 1351, 1365-1425, 1429-1457, 1459, 1461-1730, 1735, 1739-2397, 2533-2541, 2544-2556, 2558, 2559, 2561-2562 or 2563. Also provided are isolated polynucleotides and polypeptides which can be used to increase nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress tolerance of a plant of a plant. |
US10208313B2 |
Coryneform bacterium transformant and process for producing organic compound using the same
A coryneform bacterium transformant engineered by the following (A) to (D): (A) enhancement of 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase activity; (B) prevention, inhibition, or reduction of intracellular sugar uptake mediated by phosphotransferase system (PTS); (C) enhancement of intracellular sugar uptake activity mediated by a sugar transporter different from phosphotransferase system and enhancement of glucokinase activity; and (D) enhancement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity is capable of efficiently producing shikimic acid or the like from a sugar. |
US10208308B2 |
Matriptase inhibitors and uses thereof against orthomyxoviridae infections
The present invention provides matriptase inhibitors and compositions for treating and preventing orthomyxovirus infections such as flue infections. The present invention also provides novel compounds, compositions, methods of use, uses and kits thereof for inhibiting matriptase. Such compounds are useful for treating and prevention orthomyxovirus infections, such as flu infections, and for inhibiting tumor growth, progression and/or metastasis. |
US10208307B2 |
Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases
The present invention provides iRNA agents, e.g., double stranded iRNA agents, that target the transthyretin (TTR) gene and methods of using such iRNA agents for treating or preventing TTR-associated diseases. |
US10208305B2 |
RNA-YY1 interactions
Methods relating to obtaining libraries of YY1-binding long non-coding RNAs, libraries obtained thereby, and methods of use thereof. |
US10208303B2 |
Solid-core ring-magnet
A solid-core ring-magnet having one or more cavities is provided. The magnet can have an overall cylindrical shape or a rectangular-prism shape. In either case, a portion of cavity walls of the magnet are ring shaped, causing the magnetic field lines to emanate from the magnet in the shape of a ring. The diameter of the ring shaped cavities can be constant throughout, constant through a portion of the cavity, variant throughout, or variant through a portion of the cavity. The cavities open to the end of the magnet, and terminate toward the core of the magnet. Also provided are systems and kits having solid-core ring-magnets. Methods of purifying a macromolecule using the solid-core ring-magnets are also provided. |
US10208302B2 |
Composite material and method of manufacturing composite material
A composite material includes: an apatite crystal in the form of a tube; and a functional component accommodated in the apatite crystal tube and constituted by a material having physical properties different from those of the apatite crystal. The apatite crystal may be a monocrystal given by the general formula M25(PO4)3X, where M2 denotes at least one element selected from the group consisting of divalent alkali earth metals and Eu, and X denotes at least one element or molecule selected from the group consisting of halogens and OH. |
US10208301B2 |
Xylanase variants and polynucleotides encoding same
The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants. |
US10208300B2 |
Extracellular hyaluronidase from Streptomyces koganeiensis
A process for preparing Streptomyces koganeiensis ATCC 31394 hyaluronidase by obtaining hyaluronidase having molecular weight of 21.6 kDalton, which has hyaluronidase activity and stability markedly higher than those of the hyaluronidase obtained from such microorganism to date. |
US10208298B2 |
Peptide-mediated delivery of RNA-guided endonuclease into cells
A composition is disclosed that comprises at least one protein component of an RNA-guided endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN protein component and CPP are covalently or non-covalently linked to each other in an RGEN protein-CPP complex. The RGEN protein-CPP complex can traverse (i) a cell membrane, or (ii) a cell wall and cell membrane, of a cell. The RGEN protein component of an RGEN protein-CPP complex in certain embodiments can be associated with a suitable RNA component to provide an RGEN capable of specific DNA targeting. Further disclosed are compositions comprising at least one protein component of a guide polynucleotide/Cas endonuclease complex and at least one CPP, as well as methods of delivering RGEN proteins into microbial cells, as well as methods of targeting DNA with RGENs. |
US10208293B2 |
Compositions and methods for the biosynthesis of vanillan or vanillin beta-D-glucoside
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside. |
US10208292B2 |
ICP0-mediated enhanced expression system
Methods and compositions for increasing the production of recombinant proteins by introducing ICP0 to cells capable of producing a recombinant protein are encompassed. In one method, the recombinant protein is a protein that is required for the replication of a replication defective virus, wherein the recombinant protein is provided to the replication defective virus in trans. |
US10208290B2 |
Virion display array for profiling functions and interactions of human membrane proteins
Provided herein are recombinant virion arrays comprising human membrane bound proteins that retain their native conformations and/or interactions, recombinant HSV-1 virions, and methods of use including high-content, high-throughput assays for screening for ligands and/or drugs that bind human membrane bound proteins, diagnostic assays, proteomic assays, and biosensor assays. Also provided are recombinant HSV-1 virions comprising an envelope comprising a plurality of heterologous membrane bound proteins that retain their native conformations and/or interactions as well as recombinant HSV-1 bacterial artificial chromosome (BAC) clones encoding heterologous membrane polypeptides. |
US10208289B2 |
Micro blood vessels and tissue ducts
A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves. |
US10208288B2 |
Differentiation of human embryonic stem cells into pancreatic endocrine cells
The present invention provides methods to promote differentiation of pancreatic endoderm cells to pancreatic endocrine rich clusters and to enhance insulin expression in hormone-expressing cells. |
US10208287B2 |
CD82-positive cardiac progenitor cells
An object of the present invention is to provide a myocardial progenitor cell that is specifically induced to differentiate into a cardiomyocyte, and a method for preparing the myocardial progenitor cell. A method for preparing a CD82-positive cell includes, in sequence, a step (a) of obtaining stem cells, a step (b) of subjecting the stem cells to induction treatment of differentiation into cardiovascular cells, and a step (c) of separating, from the stem cells having been subjected to the induction treatment of differentiation in the step (b), a CD82-positive cell being negative for at least one cell surface marker selected from CD73, CD44, CD105, CD121a, CD18, and CD120a. This method enables preparation of a CD82-positive cell for use as a myocardial progenitor cell. |
US10208284B2 |
Cell-seeding and -culturing device
Provided is a device for seeding cells in a plurality of cell arrangement areas in a simple manner and a short period of time. A seeding and culturing device (1) for cells capable of forming a nerve network, the device comprising a cell-culturing substrate (2) having a plurality of cell arrangement areas (8) enclosed by a plurality of projecting parts, and a flow channel substrate (3) arranged on the cell-cultivating substrate (2) and having a plurality of through-holes (14), wherein the through-holes (14) are configured so as to provide flow channels in which the upper surface side of the substrate is an entrance (15) and the lower surface side of the substrate is an exit, and the exit (16) of the flow channels is positioned above any of the cell arrangement areas. |
US10208283B2 |
Methods and systems for manipulating particles using a fluidized bed
The present invention comprises methods and systems for manipulation of media and particles, whether inert materials or biomaterials, such as cells in suspension cell culture. The methods and systems comprise use of an apparatus comprising a rotating chamber wherein the actions of the combined forces of gravity, fluid flow force and centrifugal force form a fluidized bed within the rotating chamber. |
US10208282B2 |
System and method for magnetic self-assembly
In one aspect, the present disclosure provides a method for self-assembly of magnetic building blocks, including distributing a plurality of building blocks in a liquid medium, each of the plurality of building blocks having a plurality of stable radicals, establishing a magnetic field interacting with at least a portion of the plurality of building blocks, guiding with the magnetic field the portion of the plurality of building blocks from a first location in the liquid medium to a second location in the liquid medium, assembling into a first construct the portion of the plurality of building blocks proximate the second location, and treating the first construct with at least one antioxidant to neutralize at least in part the plurality of stable radicals. |
US10208281B2 |
Method for cultivating cells in adhesion culture by using a cell culture carrier in capsule form, and cell culture carrier therefor
The invention relates to a method for cultivating cells in adhesion culture, comprising at least the following steps: a) dissolving or suspending a cross-linkable, biocompatible material having adhesion points for cells in a cell culture medium; b) suspending cells in the cell culture medium, which contains the cross-linkable, biocompatible material, or in a medium that contains at least one component that is required for the cross-linking of the cross-linkable, biocompatible material; c) introducing the cell suspension into a medium in drops under conditions that initiate or permit the cross-linking of the biocompatible material, wherein either the cell suspension or the medium into which the cell suspension is introduced in drops contains the cross-linkable biocompatible material; d) forming stable, preferably porous capsules from cross-linked biocompatible material, which capsules contain incorporated adherent cells; e) proliferating the adherent cells in the capsules for a specified time period; f) breaking up the capsule material by means of a physical or chemical stimulus and releasing the cells as a cell suspension. In an especially preferred embodiment of the invention, the method is performed cyclically, in that the cells released in step f) are suspended anew in a cell culture medium that contains a cross-linkable, biocompatible material or in a medium that contains at least one component that is required for the cross-linking of the cross-linkable, biocompatible material and steps c)-f) are repeated at least once. |
US10208278B1 |
Trickle-film bioreactor and methods of use thereof
A method for culturing suspended photosynthetic organisms is provided, comprising culturing the photosynthetic organism in a flowing thin film photobioreactor, wherein the flowing thin film photobioreactor comprises a light source and a trickle-film insert comprising screen material. In a preferred embodiment, the organism is Rhodobacter grown anaerobically; In an additional preferred embodiment, the organism is Botryococcus braunii. |
US10208275B2 |
Polyelectrolyte complexes
The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide a cleaning benefit and surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellency, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions and at least one oxidant selected from the group: alkaline metal salts and/or alkaline earth metal salts of hypochlorous acid, hypochlorous acid, solubilized chlorine, any source of free chlorine, acidic sodium chlorite, active chlorine generating compound and any combinations or mixtures thereof. Also provided are means to form stable associative polyelectrolyte complexes with at least one oxidant in aqueous solutions having R values from about 0.10 to 20. |
US10208274B1 |
Brewing vessel cleaning composition and related methods of use
An acidic cleaning composition and related methods of use for rapidly cleaning and sanitizing hard contact surfaces in the food and beverage industry. The acidic cleaning composition includes a concentrated acidic solution, a strong oxidizer, a surfactant, a suitable solvent and/or sufficient quantities of water. The acidic cleaning composition rapidly removes soils from food and beverage contact surfaces such as, for example, brewing vats and kegs, without requiring CO2 be removed from the brewery vessel. The acidic cleaning composition can be in a concentrated form for dilution with additional dilution water at ambient or faucet temperature as opposed to requiring the use of “hot” water. The acidic cleaning composition is free-rinsing leaving essentially no residue on the contact surface. The surfactant provides low-foam properties so as to avoid cavitation and damage within a pump assembly. |
US10208270B2 |
Acyltransferases and uses thereof in fatty acid production
The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods. |
US10208269B2 |
Low viscosity ester lubricant and method for using
According to the present disclosure, there is provided a high-temperature lubricant composition. The composition has an amount of an ester. The ester exhibits a kinematic viscosity at 100° C. of 1 to 4 centistokes and a kinematic viscosity ratio at 150° C./100° C. of 0.6 or higher. The composition is at a temperature of 100° C. to 150° C. There is also another lubricating composition having the ester and a polymeric viscosity modifier. There are also methods for using the lubricating compositions in the crankcase of an engine. |
US10208263B2 |
Modular hybrid plasma gasifier for use in converting combustible material to synthesis gas
A hybrid plasma reactor system that uses multiple sets of long electrodes that are placed longitudinally opposite each other within modular plasma units. The plasma units can be stacked to form an elongated plasma zone. The electrode assemblies extend into access ports. Each of the electrode assemblies has an electrode tip mounted in a tubular support jacket. A gas conduit for a supplied working gas surrounds at least a portion of the tubular support jacket. An arc is created at the electrode tip. A working gas flows through the gas conduit and is directed into the arc, therein creating plasma within the internal plasma zone. |
US10208262B2 |
Process for catalytic gasification of carbonaceous feedstock
An improved process for the catalytic gasification of a carbonaceous feedstock in a dual fluidized bed reactor for producing synthesis gas is disclosed. The disclosure uses γ-alumina as a catalyst support i and heat carrier in the gasification zone (102). The gasification zone (102) is operated at 700-750° C. to prevent substantial conversion of γ-alumina to α-alumina, which would manifest in the enablement of high catalyst loading and high recyclability. The catalyst is an alkali metal, preferably K2CO3, so that conversion proportional to total K2CO3 to solid carbon ratio is achieved with as high K2CO3 loading as 50 wt % on the solid support. The combustion zone (140) is operated at 800°-840° C., to prevent any conversion of the γ-alumina to α-alumina, so that catalyst recyclability of up to 98% is achieved between two successive cycles. |
US10208247B2 |
Aluminate fluorescent material, light emitting device using the same, and method of producing aluminate fluorescent material
Provided is an aluminate fluorescent material having a high emission intensity and having a composition containing a first element that contains one or more of Ba and Sr, and a second element that contains Mg and Mn. In the composition, when a molar ratio of Al is 10, a total molar ratio of the first element is a parameter a, a total molar ratio of the second element is a parameter b, a molar ratio of Sr is a product of a parameter m and the parameter a, a molar ratio of Mn is a product of a parameter n and the parameter b. The parameters a and b satisfy 0.5 |
US10208239B2 |
Method of removing water-based filter cake
A method of removing a water-based filter cake from a wellbore, the method comprising: contacting the filter cake with a mixture comprising: a non-aqueous, polar solvent; an agent selected to breakdown the filter cake; said mixture comprising <5 wt % water and preferably being essentially anhydrous. The low water content of the mixture actually slows the degradation of the filter cake which has surprisingly been found to be more effective as it allows a more even removal of the filter cake and a more efficient use of the mixture; without the tendency to create local holes in the filter cake where the mixture could escape. Embodiments of the present invention use a polar solvent with a dielectric constant of more than (15), preferably more than (30) such as (15) monoethylene glycol (MEG). In preferred embodiments the agent comprises a salt based on potassium EDTA (ethylenediaminetetraacetic acid). |
US10208233B2 |
Dust control in oil field applications
A method and a composition for suppressing and eliminating dust particulate. The composition includes an aqueous gelling solution, and a proppant particulate. The aqueous gelling solution and the proppant particulate are combined to create a mixture. The aqueous gelling solution and the proppant particulate may be combined using at least one of composition spraying the aqueous gelling solution, mist spraying the aqueous gelling solution, and atomized spraying aqueous gelling solution. The mixture may include around 0.1 weight percent to 5 weight percent w/v of the aqueous gelling solution. The gelling agent may include a suitable viscosifying polymer. The suitable viscosifying polymer may include at least one of natural polymers, derivatives of natural polymers, synthetic polymers, biopolymers, and any combination thereof, guar, xanthan, diutan, scleroglucan, high-molecular weight polysaccharides, any derivative thereof, and any combination thereof, hydropropyl guar (HPG), carboxymethyl guar (CMG), and carboxymethylhydroxypropyl guar (CMHPG). |
US10208231B2 |
High performance sealant composition for tire repair
A high performance sealant for repairing punctures in tires includes a highly filtered natural rubber latex, an ultra-fine inorganic powder, a polyamide suspension, and an antifreeze agent that includes water and at least one of ethylene glycol and propylene glycol. The high performance sealant can readily pass through a valve stem of a tire without removing the core and seal, and provides a strong and durable sealing of the puncture. |
US10208230B2 |
One component, low temperature cure coating formed via a double layer curing mechanism
Shelf-stable low temperature cure coating compositions that include a hydroxy-functional resin, a crosslinking agent, and a catalyst that does not catalyze the crosslinking reaction between hydroxy-functional resin and the crosslinking agent contained therein, but instead between a hydroxy-functional resin and a crosslinking agent contained in a different low temperature cure coating composition. In addition, low temperature cure composite coatings that include: a basecoat of a low temperature cure coating composition containing a first hydroxy-functional resin, a first crosslinking agent, and a first catalyst; and a topcoat containing a second hydroxy-functional resin, a second crosslinking agent, and a second catalyst, where the first catalyst migrates into the topcoat from the basecoat and catalyzes the reaction between the second hydroxy-functional resin and crosslinking agent, and the second catalyst migrates into the basecoat from the topcoat and catalyzes the reaction between the first hydroxy-functional resin and crosslinking agent. |
US10208224B2 |
Interlayer composition for electronic printing
The present disclosure is directed to a composition including a polyvinyl butyral represented by the following formula: wherein A, B and C represent a proportion of corresponding repeat units expressed as a weight percent, wherein each repeat unit is randomly distributed along a polymer chain and wherein the sum of A, B and C is about 100 weight percent; a poly(melamine-co-formaldehyde) based polymer and an anhydride. Devices coated with the composition and cured films formed from the composition comprising conductive features are also provided. |
US10208218B2 |
Method for ink jetting opaque ink composition
A method of inkjet printing includes ink jetting an aqueous inkjet ink composition to form a white printed image on a substrate. The aqueous inkjet ink composition comprises particles of titanium dioxide that are present in an amount of at least 4 to 15 weight % and the particles have a 95th percentile particle size of less than 200 nm and a 50th percentile particle size of less than 130 nm. The titanium dioxide particles are dispersed within the aqueous inkjet ink composition using a dispersing polymer that is a styrene-(meth)acrylic acid polymer, styrene-maleic anhydride polymer, or styrene-maleic acid polymer and the weight ratio of the titanium dioxide particles to the dispersing polymer is from 19:1 to and including 2:1. |
US10208216B2 |
Water dispersion of gel particles, producing method thereof, and image forming method
A water dispersion of gel particles, in which the gel particles having a three-dimensional crosslinked structure including at least one of Polymer Structure (1) or Polymer Structure (2), having a hydrophilic group and a polymerizable group, and including photopolymerization initiators are dispersed in water, a method of producing the water dispersion, and an image forming method using the water dispersion are provided. P1 and P2 represent a polymer chain consisting of polyester and the like and having a number-average molecular weight of 500 or greater, Z11 represents a (n1+1)-valent group, Z12 represents a (m1+1)-valent group, m1, n1 and n2 each represent an integer of 1 or greater, X1 represents a single bond, a —CH2— group, or a —NH— group, Z21 represents a (n2+1)-valent group, R1 represents a hydrocarbon group that may include a hetero atom. |
US10208212B2 |
Near-infrared absorption composition, curable composition, cured film, near-infrared cut filter, solid-state imaging device, infrared sensor, camera module, processed coloring agent, and method of manufacturing processed coloring agent
The near-infrared absorption composition includes a processed coloring agent obtained by coating a near-infrared absorption coloring agent with a resin having one or more selected from a coloring agent structure, a heterocyclic structure, and an acyclic hetero atom-containing group. The near-infrared absorption coloring agent is preferably one or more selected from a phthalocyanine coloring agent, a perylene coloring agent, a pyrrolopyrrole coloring agent, a cyanine coloring agent, a dithiol metal complex coloring agent, a naphthoquinone coloring agent, a diimmonium coloring agent, an azo coloring agent, and a squarylium coloring agent and more preferably a pyrrolopyrrole coloring agent. |
US10208211B2 |
Conductive pastes using bimodal particle size distribution
Monodispersed metal nanoparticles are prepared by preparing a homogeneous metal complex solution by mixing metal salt with a complexing agent in solvent. A precipitating agent is added into the homogeneous metal complex solution to form a slurry. A homogeneous mixture of reducing agent and solvent is added to perform reducing reaction on the slurry to form metal nanoparticles in a controlled environment under gas purge. A capping agent is added to modify surface properties of metal nanoparticles. The metal nanoparticles are washed and the metal nanoparticles are recovered by phase extraction or centrifugation. The technique can be used to prepare conductive pastes with bimodal particle size distribution. |
US10208210B2 |
Hydrophilic oil repellent and production method of same, surface coating material, coating film, resin composition, oil-water separation filter material, and porous body
The hydrophilic oil repellent includes one or more types of nitrogen-containing fluorine-based compounds. The nitrogen-containing fluorine-based compound includes any one hydrophilicity imparting group selected from the group consisting of anion type hydrophilicity imparting groups, cation type hydrophilicity imparting groups, and amphoteric type hydrophilicity imparting groups in the molecule. |
US10208208B2 |
Composite phthalocyanine microparticles and method for producing same
Composite phthalocyanine microparticles of a nano-order level, preferably on the order of 100 nm, that are optimal as a coloring material are provided; and a method for producing the same. The method for producing composite phthalocyanine microparticles includes a step (1) for preparing a dissolved solution by dissolving at least copper phthalocyanine and titanyl phthalocyanine and/or cobalt phthalocyanine as raw materials in a first solvent, a step (2) for precipitating composite phthalocyanine by mixing the dissolved solution obtained in step (1) with a second solvent that serves as a poor solvent of the abovementioned raw materials, and a step (3) for causing an organic solvent to act on the composite phthalocyanine obtained in step (2). Also provided are composite phthalocyanine microparticles containing at least copper phthalocyanine and titanyl phthalocyanine and/or cobalt phthalocyanine, the composite phthalocyanine microparticles having an aspect ratio of 1.1-2.5 and a particle size of 5-100 nm. |
US10208207B2 |
Electrophoretic particles and processes for the production thereof
Polymer shells similar to those described in U.S. Pat. No. 6,822,782 can be formed on pigment particles by (a) physi-sorping a reagent comprising polymerizable groups on to the pigment particles by treating the particle with a reagent having a polymerizable or polymerization-initiating group, such that the reagent will not desorb from the particle surface when the particle is placed in a hydrocarbon medium; or (b) treating pigment particles bearing nucleophilic groups with a reagent having a polymerizable or polymerization-initiating group, and an electrophilic group, thus attaching the polymerizable or polymerization-initiating groups to the particle surface. The zeta potential of the pigment particles can be varied by a process similar to (b) but using a reagent which does not have a polymerizable or polymerization-initiating group. |
US10208205B2 |
Recycling polyamide airbags
A composition, in particular for molding, including a mixture of a polyamide material, a powder made from airbag scraps, and optionally a reinforcing filler. Also described, is an article formed from the composition. |
US10208202B2 |
Thermoplastic resin composition containing polycarbonate resin, graft copolymer, and copolymer, and molded article thereof
A thermoplastic resin composition includes 10 to 95 parts by weight of a polycarbonate resin (A); 5 to 90 parts by weight of a graft copolymer (B); and 0 to 50 parts by weight of a copolymer (C). The graft copolymer (B) is produced by the graft polymerization of 10 to 80 parts by weight of a rubbery polymer with 20 to 90 parts by weight of a monomer component including an aromatic vinyl monomer and/or a cyanide vinyl monomer, wherein the rubbery polymer has a weight average particle size of 150 to 450 nm and also has a 10 wt % particle size of 50 to 250 nm and a 90 wt % particle size of 450 to 650 nm in a particle size cumulative weight fraction. The copolymer (C) is produced by copolymerizing an aromatic vinyl monomer, a cyanide vinyl monomer and another vinyl monomer with one another. |
US10208199B2 |
Polyester resin composition and molded article produced using the same
A polyester resin composition and a molded article produced using the same. The polyester resin composition includes: a crystalline polyester resin; a non-crystalline polyester resin; and glass fibers, wherein a weight ratio of the crystalline polyester resin to the non-crystalline polyester resin ranges from about 4:1 to about 1:1. |
US10208198B2 |
Solventborne binder for an intumescent coating
Solventborne binder compositions which include a copolymer obtained by reacting a mixture of monomers in the presence of an organic solvent, wherein the monomer mixture includes an ethylenically unsaturated monomer and a vinyl ester monomer having a formula CH2CH—X—C(═O)—R, where R is a linear or branched alkyl group having 2 to 18 carbon atoms, an aromatic group having 6 to 12 carbon atoms, or R is bonded to X to form a 5- to 7-member ring, and X is O. Intumescent coatings containing the solventborne binder compositions, and substrates coated with the intumescent coatings are also disclosed. |
US10208195B2 |
Polypropylene resin composition and cable cladded with the same
The present invention relates to a polypropylene resin composition and a cable cladded with the same. More particularly, the present invention relates to a polypropylene resin composition, including 25 to 35% by weight of a polypropylene polymer, 15 to 25% by weight of a styrene block copolymer, 15 to 25% by weight of a poly(arylene ether) resin, 26 to 35% by weight of a phosphorus flame retardant, and 0 to 10% by weight of a processing additive.In accordance with the present invention, a polypropylene resin composition including a small amount of flame retardant but exhibiting excellent flame resistance, insulation performance, processability, and property balance, and a cable cladded with the same are provided. |
US10208191B2 |
Rotomolded articles comprising a layer of polyolefin and polyester
A rotomolded article can have one or more layers, including a layer A. The layer A can have from 50 to 99.4 wt % of a polyolefin, from 0.5 to 50 wt % of a polyester, and from 0.1 to 20 wt % of a co- or ter-polymer. The co- or ter-polymer can have 50 to 99.9 wt % of an ethylene or a styrene monomer, 0.1 to 50 wt % of an unsaturated anhydride-containing monomer, epoxide-containing monomer or carboxylic acid-containing monomer, and 0 to 50 wt % (meth)acrylic ester monomer. |
US10208183B2 |
Curable composition, film, and method of producing film
Provided is a curable composition, including a polymerization initiator; a polymerizable compound; and an internal addition type release agent having a hydrophilic functional group, in which the internal addition type release agent is prevented from being unevenly distributed in a gas-liquid interface of the curable composition. |
US10208182B2 |
Polypropylene composition suitable for primerless painting
The present invention is directed to a polypropylene composition (C), an article comprising the polypropylene composition (C) and the use of the polypropylene composition (C) to reduce paintability failure of a molded article. The polypropylene composition (C) comprises (a) 40.0 to 80.0 wt. %, based on the total weight of the composition, of a propylene copolymer (R-PP) having: (a1) a comonomer content in the range of 1.5 to 8.0 wt. %, and (a2) a melt flow rate MFR2 (230 ° C.) measured according to ISO 1133 in the range of 5.0 to 100.0 g/10 min, and (b) 20.0 to 40.0 wt. %, based on the total weight of the composition, of a mineral filler (F) being selected from the group consisting of talcum, wollastonite, kaolin, and mica, wherein the polypropylene composition (C) has a melt flow rate MFR2 (230 ° C.) measured according to ISO 1133 in the range of 5.0 to 45.0 g/10 min. |
US10208179B2 |
Flame retardant thermally conductive polymer compositions with good flow property and uses thereof
The invention concerns compositions comprising (a) from about 20 wt % to about 80 wt % of a polymer component; (b) from about 10 wt % to about 70 wt % of a flame retardant component; and (c) from about 0.01 wt % to about 5 wt % of an acid component; wherein the combined weight percent value of all components does not exceed 100 wt %; wherein all weight percent values are based on the total weight of the composition; and wherein the composition has: (i) a thermal conductivity of at least about 1.5 W/mK for through plane thermal conductivity; (ii) flame retardancy of at least VI at 0.8 mm using the UL94 test standard; and (iii) melt volume flow rate of at least 10 g/cm3 using ASTM D 1238. |
US10208176B2 |
Composite material with thermoplastic toughened novolac-based epoxy resin matrix
Pre-impregnated composite material (prepreg) that can be cured/molded to form aerospace composite parts. The prepreg includes carbon reinforcing fibers and an uncured resin matrix. The resin matrix includes an epoxy component that is a combination of a hydrocarbon epoxy novolac resin and a trifunctional epoxy resin and a tetrafunctional epoxy resin. The resin matrix includes polyethersulfone as a toughening agent and a thermoplastic particle component that includes a mixture of polyamide particles and polyimide particles. |
US10208174B2 |
Random mat and fiber-reinforced composite material shaped product
There is provided a random mat including reinforcing fibers having an average fiber length of 3 to 100 mm and a thermoplastic resin, wherein the reinforcing fibers satisfy the following i) to iii). i) The reinforcing fibers have a weight-average fiber width (Ww) which satisfies the following equation (1). 0 mm |
US10208173B2 |
Sizing agent-coated reinforcing fibers, method for producing sizing agent-coated reinforcing fibers, prepreg, and fiber-reinforced composite material
Sizing agent-coated reinforcing fibers include reinforcing fibers and a sizing agent containing a polyrotaxane, the reinforcing fibers being coated with the sizing agent. Provided are sizing agent-coated reinforcing fibers that provide a fiber-reinforced composite material with excellent mechanical properties, a method for producing the sizing agent-coated reinforcing fibers, a prepreg including the sizing agent-coated reinforcing fibers, and a fiber-reinforced composite material with excellent mechanical properties including the sizing agent-coated reinforcing fibers. |
US10208170B2 |
Process for producing surface-postcrosslinked water-absorbent polymer particles
The present invention relates to a process for producing surface-postcrosslinked water-absorbent polymer particles by coating of water-absorbent polymer particles having a content of residual monomers in the range from 0.03 to 15% by weight with at least one surface-postcrosslinker and thermal surface-postcrosslinking at temperatures in the range from 100 to 180° C. |
US10208167B2 |
Cyclodextrins with one or more poly(ethylene glycol) units, inclusion compounds and drug delivery vehicles including the same, and methods of making and using the same
A compound comprising a cyclodextrin and a monoalkoxy polyethylene glycol linked thereto through an ether bond (a “pegylated cyclodextrin”) is disclosed, as are drug delivery vehicles and pharmaceutical formulations including the same, and methods for making the compound and the drug delivery vehicle and for delivering the drug to a patient in need thereof. The method of making includes the steps of creating either a tosylated monoalkoxy polyethylene glycol or a tosylated cyclodextrin, and either reacting the tosylated monoalkoxy polyethylene glycol with a deprotonated cyclodextrin, or reacting the tosylated cyclodextrin with a deprotonated monoalkoxy polyethylene glycol. The present pegylated cyclodextrin readily forms an inclusion compound with certain drugs to protect the drug against adverse interactions with mucin (e.g., in a mucus membrane). |
US10208164B2 |
Curable silicone composition, curable hot-melt silicone, and optical device
A curable silicone composition comprises: (A) an organopolysiloxane represented by a specific average unit formula; optionally, (B) an organopolysiloxane represented by a specific average unit formula; (C) an organohydrogenpolysiloxane represented by a specific average composition formula; and (D) a hydrosilylation catalyst. A curable hot-melt silicone is obtained by subjecting the curable silicone composition to a hydrosilylation reaction to a degree that does not form a cured product. The curable hot-melt silicone is non-flowable at 25° C. and has a melt viscosity at 100° C. of 5000 Pa·s or less. The curable silicone composition provides a cured product having excellent heat resistance and light resistance after being cured. The curable hot-melt silicone is non-flowable at room temperature, has low surface stickiness, and is readily melted by heating. |
US10208158B2 |
Super elastic epoxy hydrogel
Described is a super elastic epoxy hydrogel that is easy to manufacture and can be engineered for various performance enhancements of the polymer. Also described are methods of enhancing the performance of this hydrogel and other hydrogels. Various polymer hydrogel composites, structures, and their uses are included, such as the actuator element comprising the hydrogel of the invention depicted in FIG. 2. |
US10208154B2 |
Formulations for chemical mechanical polishing pads and CMP pads made therewith
A two component composition for making chemical mechanical polishing pad for polishing a semiconductor substrate is provided comprising a liquid aromatic isocyanate component having an unreacted isocyanate (NCO) concentration of from 15 to 40 wt. %, based on the total solids weight of the aromatic isocyanate component, such as methylene di(phenylisocyanate) (MDI), a liquid polyol component of a polyol having a polyether backbone and having from 5 to 7 hydroxyl groups per molecule, and a curative of one or more polyamine or diamine, wherein the reaction mixture comprises 50 to 65 wt. % of hard segment materials, based on the total weight of the reaction mixture. The composition when mixed cured to form a polyurethane reaction product. Also provided are CMP polishing pads made from the polyurethane reaction product by spraying the composition into a mold. |
US10208153B2 |
Adhesive compositions
There is provided an adhesive composition comprising (a) a polyisocyanate component comprising (i) monomeric 4,4′ methylene diphenyl diisocyanate and (ii) an isocyanate functional prepolymer that is the reaction product of a prepolymer reactant mixture comprising (A) monomeric 4,4′ methylene diphenyl diisocyanate, and (B) one or more diol having OH equivalent weight of 225 or less, and (C) one or more triol having OH equivalent weight of 1400 or more, and (b) a polyol component comprising one or more polyol. |
US10208151B2 |
Method for preparing large-size diene-based rubber latex and acrylonitrile-butadiene-styrene graft copolymer comprising the same
The present invention relates to a method for preparing a diene-based rubber latex having improved impact strength, gloss and flexibility, diene-based rubber latex prepared therefrom, and an acrylonitrile-butadiene-styrene graft copolymer having improved impact strength and production yield while having reduced rubber solid content ratio by comprising the same. |
US10208149B2 |
Method for producing water-absorbent polymer particles with a higher permeability by polymerising droplets of a monomer solution
A process for preparing water-absorbing polymer beads with high permeability by polymerizing droplets of a monomer solution, comprising monomers bearing acid groups, in a gas phase surrounding the droplets, wherein the monomer solution comprises polyvalent cations and the polymer beads have a mean diameter of at least 150 μm. |
US10208135B2 |
Catalyst components for the polymerization of olefins
A catalyst component comprising Ti, Mg, Cl, and an electron donor compound having porosity of at least 0.2 cm3/g and characterized by the fact that it further comprises Cu oxide, with the proviso that when the electron donor compound is selected from esters of phthalic acids, the porosity is of at least 0.45 cm3/g. |
US10208133B2 |
Site-selective modification of polysaccharides and applications thereof
The present invention relates to site-selective modification of polysaccharides at their reducing end by conjugation with a single aminoxy-Regioselective Addressable Functionalized Template (RAFT) peptide. |
US10208132B2 |
Method of modifying polymers
A method of modifying a polymer having hydroxyl groups, selected from the group of polysaccharides and lignin, to give a modified polymer comprising the step of contacting said polymer with at least one organic phosphonate salt in order to chemically modify the polymer, said organic phosphonate salt being in a liquid phase. The method of polymer modification provides novel polymers. Modified polymers obtained from a polymer having been treated with at least one organic phosphonate salt are also disclosed. The modified polymers can be used as such or separated and optionally recovered from the solution, optionally being formed into particular materials or shapes. |
US10208131B2 |
Artificially produced polyclonal immunoglobulin preparation
The present invention intended to provide an artificial polyclonal immunoglobulin composition having a high therapeutic effect and high safety, and being capable of stable supply in a large amount. Specifically provided is an artificial polyclonal immunoglobulin composition containing, as active ingredients, 204 polypeptides represented by amino acid sequences set forth in SEQ ID NOS: 1 to 204 of the sequence listing, the polypeptides being plural kinds of single chain variable fragments (also referred to as ScFvs) each comprised of a heavy chain variable region, heavy chain constant region 1, and hinge region (VH-CH1-hinge) of an immunoglobulin, in which the heavy chain variable regions are different each other. |
US10208126B2 |
Methods of treating aplastic anemia by administering anti-CD26 antibodies
The present invention pertains to novel antibodies capable of binding to CD26, as well as to their use as a medicament. Moreover, the present invention provides antibodies for use in treating and/or preventing Graft-versus-Host Disease (GvHD), for use in treating Aplastic Anemia and/or for use in promoting engraftment after haematopoietic stem cell transplantation. Furthermore, the present invention provides pharmaceutical compositions comprising at least one antibody of the present invention, as well as provides a kit of parts. |
US10208124B2 |
Anti-CD160 specific antibodies for the treatment of eye disorders based on neoangiogenesis
The present invention relates to the use of at least one anti-CD 160 antibody, preferably a compound selected from CL1-R2 monoclonal antibody (which may be obtained by the hybridoma CNCM 1-3204), its conservative fragments and its conservative derivatives, for preparing a drug designed to treat neovascular eye diseases. |
US10208113B2 |
Interferon α and ω antibody antagonists
The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing. |
US10208112B2 |
Anti-CGRP compositions and use thereof
The present invention is directed to antibodies and fragments thereof having binding specificity for CGRP. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-CGRP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-CGRP antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-CGRP antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with CGRP. |
US10208111B2 |
Alpha-synuclein antibodies and uses thereof
The invention describes antibodies having a high affinity for aggregated forms of α-synuclein and a low affinity for monomeric forms of α-synuclein. The antibodies are useful in the diagnosis of neurodegenerative diseases. |
US10208110B2 |
Compositions and methods related to recombinant antibodies to histone posttranslational modifications
Embodiments concern compositions and methods involving recombinant antibodies to histone post-translational modifications. The invention provides compositions and methods for histone methyltransferase assays. In certain embodiments, the compositions and methods involve a recombinant antibody that binds histone H3 fragment harboring biomarkers such as H3K9me3 mark, H3K4me3 mark, H3K36me3 mark, H3K27me3, H3K9me3 and H3S10phos or a recombinant antibody that binds histone H4 fragment harboring H4K20me3 mark. |
US10208106B2 |
Removal of serine proteases by treatment with finely divided silicon dioxide
The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease and\or serine protease zymogen content. Among yet other aspects, the present invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced serine protease and/or serine protease zymogen content. Yet other aspects include methods for treating, managing, and/or preventing a disease comprising the administration of a plasma-derived protein composition having a reduced serine protease or serine protease zymogen content. |
US10208105B2 |
Immunoglobulin constant region Fc receptor binding agents
IVIG replacement compounds are derived from recombinant and/or biochemical creation of immunologically active biomimetic(s). These replacement compounds are then screened in vitro to assess each replacement compound's efficiency at modulating immune function. Particular replacement compounds are selected for further in vivo validation and dosage/administration optimization. Finally, the replacement compounds are used to treat a wide range of diseases, including inflammatory and autoimmune diseases. |
US10208101B2 |
Recombinant fibrinogen high-production line and method for producing same
The present invention provides a recombinant strain highly producing fibrinogen which is an animal cell strain coexpressing a fibrinogen and an α2PI and/or PAI-2, genes encoding Aα chain, Bβ chain and γ chain of fibrinogen, a production method of a recombinant strain highly producing fibrinogen, including introducing gene(s) encoding α2PI and/or PAI-2 into an animal cell, and coexpressing fibrinogen and α2PI and/or PAI-2 in the animal cell, and a production method of a recombinant fibrinogen including culturing a recombinant strain highly producing fibrinogen in a medium, and recovering fibrinogen from the obtained culture. |
US10208097B2 |
Method for treating vascular stenosis or occlusive disease due to thrombi by administering a saxatilin-fc fusion protein
The present invention relates to a saxatilin derivative having an increased half life and a use thereof. The saxatilin derivative of the present invention has thrombolytic ability similar to that of saxatilin, which is the mother protein, a remarkably increased protein half life, and efficiently dissolves, for long period of time, blood clots already formed in blood vessels of an animal model with a FeCl3-induced carotid by using the same. Therefore, a composition containing, as an active ingredient, the saxatilin derivative of the present invention does not cause reocclusion after penetration and effectively opens to microvessels, and is thus very useful for treating angiostenosis or occlusive diseases (for example, cerebrovascular diseases, cardiovascular diseases, arteriosclerotic vascular diseases, coronary artery diseases, and peripheral vascular diseases). |
US10208096B2 |
Function suppression type of genetically-modified rhodocytin mutant
According to the present invention, a mutant rhodocytin lacking platelet aggregation ability is provided. According to the present invention, a pharmaceutical composition including a mutant rhodocytin lacking platelet aggregation ability is provided. According to the present invention, there is provided a method for inhibiting platelet aggregation by a platelet aggregating substance, including administering a pharmaceutical composition including a mutant rhodocytin lacking platelet aggregation ability to a subject in need thereof. |
US10208094B2 |
Multimeric immunoglobulin-binding domain
A multimeric immunoglobulin-binding protein having improved properties as an affinity ligand for affinity chromatography, and an insoluble support immobilizing such a multimer. The immunoglobulin-binding protein is represented by the formula: (R1)n-(R2)m, or (R2)m-(R1)n. R2 is an immunoglobulin-binding domain including an amino acid residue that covalently bonds to an insoluble support upon immobilization reaction with the insoluble support, and R1 is an immunoglobulin-binding domain without containing an amino acid residue the presence of which in the sequence compared to when it is absent in the sequence reduces the immunoglobulin-binding activity of the support yielded by the immobilization reaction. The immunoglobulin-binding protein satisfies: (1) n is an integer of 5 to 9; (2) m is an integer of 1 or 2; (3) the n (R1) domains may or may not have the same sequence; and (4) the total number of domains (n+m) is 6 to 10. |
US10208093B2 |
Plasmid, method and kit thereof for producing heat labile enterotoxin B-subunit
The present invention provides a plasmid, method and kit for producing heat labile enterotoxin B-subunit based on a Bacillus subtilis expression system. By comparing with the conventional method in the art, the present invention has the advantages of high safety, good yield, and simplified process and is therefore favorable for the commercialization object of heat labile enterotoxin B-subunit in the application of vaccine adjuvant. |
US10208086B2 |
Cyclin A1-targeted T-cell immunotherapy for cancer
Compositions and methods are provided for eliciting antigen-specific T-cell responses against human cyclin A1 (CCNA1), which is herein identified as a leukemia-associated antigen based on its overexpression in acute myeloid leukemia (AML) including leukemia stem cells (LSC) and in immunologically privileged testis cells, but not in other normal cell types. CCNA1-derived peptide epitopes that are immunogenic for T-cells including CTL are disclosed, as are immunotherapeutic approaches using such peptides for vaccines and generation of adoptive transfer therapeutic cells. |
US10208082B2 |
Sustained-release pharmaceutical composition for treatment and prevention of eye disease
The present invention relates to a terpenoid derivative that has the ability to activate the Keap1/Nrf2/ARE signaling pathway and is excellent in anti-inflammatory action and cytoprotective action, and a sustained-release pharmaceutical composition effective for the treatment and prevention of a posterior eye disease caused by oxidative stress, comprising the terpenoid derivative as an active ingredient. The present invention provides a local administration-type sustained-release pharmaceutical composition for the treatment or prevention of a posterior eye disease, comprising the terpenoid derivative of the present invention as an active ingredient, wherein the sustained-release pharmaceutical composition maintains a pharmacological action thereof for 1 week or longer by the sustained release of the terpenoid derivative under physiological conditions and has a base material administrable to the vitreous body and a form administrable to the vitreous body. |
US10208080B2 |
Methods of treating and/or preventing affective disorders of the nervous system (depression) using aminosterols
This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need. |
US10208078B1 |
Aesculin thiodipropionic acid ester with antioxidant activity and a method of preparing the same
A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed. |
US10208076B2 |
Renewable aromatics from lignocellulosic lignin
The present invention provides novel and improved processes for treating a lignocellulosic biomass or technical lignin using ionic liquids to obtain lignin breakdown products and polysaccharide biomass components. Recycling of ionic liquids can be included in the methods of the invention. |
US10208074B2 |
Pyrazole compounds and method for making and using the compounds
Disclosed embodiments concern novel interleukin receptor associated kinases (IRAK) inhibitors and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent an IRAK-associated disease or condition. |
US10208071B2 |
Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases
The present invention relates to a method for treating ocular inflammatory diseases in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of Formyl peptide receptor 2. |
US10208070B2 |
Synthetic blend F-POSS compositions formed from multiple feedstock materials
The present disclosure relates, in exemplary embodiments, to compositions of matter comprising synthetic blends of at least two feedstocks that produce a distribution of fluorinated polyhedral oligomeric silsesquioxane molecule structures. The present disclosure also relates, in exemplary embodiments, to methods of making such synthetic blends. |
US10208069B2 |
Precise three-dimensional supramacromolecule interconversions
A process is provided for precise self-assembly and re-arrangement of a three-dimensional terpyridine-based coordination complex. A plurality of terpyridine-containing ligands are reacted with at least one metal ion, in a pre-selected molar ratio, to form a self-assembled three-dimensional terpyridine-based coordination complex having a first configuration. A triggering event, such as exposure to light or dilution, causes the coordination complex to re-arrange to form at least two smaller, substantially identical, three-dimensional terpyridine-based coordination complexes, each having a second configuration that is different from the first configuration. Upon application of a second triggering event, such as concentration, the re-arrangement is reversed. |
US10208065B2 |
Crystalline free bases of C-Met inhibitor or crystalline acid salts thereof, and preparation methods and uses thereof
Crystalline free bases and crystalline acid salts of 9-((8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridine-3-yl)thio)-4-methyl-2H-[1,4]oxaazido[3,2-c]quinoline-3(4H)-one are disclosed as C-Met inhibitors. Their preparation methods and uses are also described. In particular, crystal forms I, II, III and IV of the free base; crystal form I of the hydrochloride salt; crystal forms I and II of the sulfate salt; crystal forms I, II, III and IV of the phosphate salt; crystal forms I, II, III, IV and V of the mesylate salt; crystal forms I, II and III of the p-toluenesulfonate salt; and crystal forms I, II and III of the 1,5-naphthalenedisulfonate salt are disclosed. Also disclosed are methods for preparing the above-mentioned crystal forms, pharmaceutical compositions thereof, methods for regulating the catalytic activity of a protein kinase, and methods of treating protein kinase-related diseases. |
US10208064B2 |
Inhibitors of the renal outer medullary potassium channel
The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention. |
US10208062B2 |
Macrocyclic quinazole derivatives and their use as MTKI
The present invention concerns the compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Z represents NH; Y represents —C3-9alkyl-, —C1-5alkyl-NR13—C1-5alkyl-, —C1-5alkyl-NR14—CO—C1-5alkyl-, —C1-2alkyl-NR21—H2—CO—NH—C1-3alkyl- or —C1-2alkyl-NR23—CO—CR16R17—NH—; X1 represents O or —O—C1-2alkyl-; X2 represents a direct bond, C1-2alkyl, —CO—C1-2alkyl or NR12—C1-2alkyl; R1 represents hydrogen or halo; R2 represents halo, acetylene or Het1 R3 represents hydrogen or cyano; R4 represents Ar4—C1-4alkyloxy-, C1-4alkyloxy- or C1-4alkyloxy substituted with one or where possible two or more substituents selected from Het2, NR7R8, hydroxy and C1-4alkyloxy-C1-4alkyloxy-; R7 represents hydrogen or C1-4alkyl; R8 represents C1-4alkyl substituted with NR25R26 or C1-4alkylsulfonyl; R12 represents hydrogen or C1-4alkyl-; R13 represents Ar6-sulfonyl or C1-6alkyloxycarbonyl optionally substituted with phenyl; R16 and R17 represents hydrogen, C1-4alkyl or R16 and R17 taken together with the carbon atom to which they are attached from a C3-6cycloalkyl; R23 represents C1-4alkyl and R23 represents hydrogen when R16 and R17 taken together with the carbon atom to which they are attached from a C3-6cycloalkyl; R25, R26, R27 and R28 each independently represent hydrogen or C1-4alkylcarbonyl; Het1 represents 2-bora-1,3-dioxolanyl; Het2 represents piperidinyl, piperazinyl, morpholinyl, thiomorpholinyl or 1,1-dioxothiomorpholinyl wherein said Het2 is optionally substituted with C1-4alkyloxycarbonyl or NR27R28—C1-4alkyl; Ar4 and Ar5 represents phenyl; Ar6 represents phenyl optionally substituted with nitro. |
US10208060B2 |
Inhibitors of HIF prolyl hydroxylase
The present invention concerns compounds of formula I or a pharmaceutically acceptable salt thereof which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier. |
US10208053B2 |
Bicyclic heteroaryl derivatives as CFTR potentiators
The present invention relates to 1,3-disubstituted-1H-pyrazolo[3,4-d]pyrimidin-4-amine derivatives and pharmaceutically acceptable salts thereof. The compounds are potentiators of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). The invention also discloses pharmaceutical compositions comprising the compounds, optionally in combination with additional therapeutic agents, and methods of potentiating, in mammals, including humans, CFTR by administration of the compounds. These compounds are useful for the treatment of cystic fibrosis (CF), asthma, bronchiectasis, chronic obstructive pulmonary disease (COPD), constipation, Diabetes mellitus, dry eye disease, pancreatitis, rhinosinusitis, Sjögren's Syndrome, and other CFTR associated disorders. |
US10208044B2 |
ACC inhibitors and uses thereof
The present invention provides for compounds of formula I as acetyl-CoA carboxylase (ACC) inhibitors. The ACC inhibitors are useful for the prevention or treatment of metabolic syndrome, including obesity, dyslipidemia and hyperlipidemia in humans. The inhibitor compounds are also capable of inhibiting the ACC enzyme found in plants, parasites and bacteria. |
US10208043B2 |
Methods for inhibiting fascin
Provided are compositions and methods for treating a condition or disorder mediated by fascin activity in a subject in need thereof which method comprises administering to the subject a therapeutically effective amount of at least one compound of any one of Formula I-a to I-n, II, II-a, II-b or III or a pharmaceutically acceptable salt thereof. |
US10208042B1 |
Multi-kinase inhibitor compound, and crystal form and use thereof
The present invention relates to a compound as represented by formula (I) or a pharmaceutically acceptable salt and stereoisomer thereof, wherein R1, R2, X, Y, P, W, and Ar are as defined in the description. The compound of formula (I) of the present invention can be used in the preparation of a drug for treating cancers mediated by abnormality of multi-kinases. Also provided is a crystal form I of a compound 4-(5-(2-chlorophenyl)-3-methyl-2,10-dihydropyrazolo[4,3-b]pyrido[4,3-e] [1,4]diazepin-8-yl)morpholine, wherein in an X-ray powder diffraction pattern of crystal form I, there are characteristic peaks at 7.4±0.2°, 17.9±0.2°, 18.9±0.2°, 19.4±0.2°, 21.5±0.2°, and 23.7±0.2°. |
US10208039B2 |
Histone demethylase inhibitors
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer, melanoma, and the like. |
US10208038B2 |
Fused tricyclic urea compounds as Raf kinase and/or Raf kinase dimer inhibitors
Provided are certain fused tricyclic urea compounds and salts thereof, compositions thereof, and methods of use therefor. |
US10208036B2 |
Process for the preparation of Apixaban and intermediates thereof
The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction. |
US10208034B2 |
Quinoline derivative
A compound represented by general formula (I) and having a quinoline skeleton has a strong Axl inhibitory activity, and therefore the compound can be an agent for treating Axl-related diseases, for example, cancer such as acute myeloid leukemia, chronic myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases. |
US10208033B2 |
β-carboline, dihydro-β-carboline and tetrahydro-β-carboline alkaloid derivatives and preparation methods same and use in aspects of preventing and treating plant viruses, fungicides and insecticides
The present invention relates to β-carboline, dihydro-β-carboline and tetrahydro-β-carboline alkaloid derivatives (I) and a method for preparing same and the use in the aspects of preventing and treating plant viruses, fungicides and insecticides. For the meaning of each group in formula (I) see the description. The β-carboline, dihydro-β-carboline and tetrahydro-β-carboline alkaloid derivatives of the present invention show a particularly ourstanding anti-plant virus activity, and also have fungicidal and insecticidal activities. |
US10208029B2 |
Photoacid compositions having extended lifetime of proton dissociation state
A photoacid includes a nucleophilic (NuH) moiety having a photodissociable proton, an electron accepting (EA) moiety, and a bridge structure (X) bonded to both the NuH moiety and EA moiety positioned between the NuH and EA moieties. The NuH and EA moieties each include respective structure so that the EA moiety bonds to a proton photodissociated form of the NuH moiety during a reversible photoinduced intramolecular reaction to form a ring, which has been found to significantly increase the lifetime of the proton dissociation state. |
US10208023B2 |
Heterocyclic inhibitors of the sodium channel
The invention relates to compounds useful in treating conditions associated with voltage-gated ion channel function, particularly conditions associated with sodium channel activity. More specifically, the invention concerns heterocyclic compounds (e.g., compounds according to any of Formulas (I)-(X) or Compounds (1)-(92) of Table 1) that are that are useful in treatment of conditions such as epilepsy, cancer, pain, migraine, Parkinson's Disease, mood disorders, schizophrenia, psychosis, tinnitus, amyotrophic lateral sclerosis, glaucoma, ischemia, spasticity disorders, obsessive compulsive disorder, restless leg syndrome and Tourette syndrome. |
US10208016B2 |
1-sulfonyl piperidine derivatives as modulators of prokineticin receptors
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof in which m, n, W, X, Y, Z, R1, R2, R3, R4 and R5 are as defined in the specification, compositions containing them and their use in therapy. |
US10208006B2 |
Processes for the preparation of 2,5-furandicarboxylic acid and intermediates and derivatives thereof
The present disclosure provides processes for the production of 2-5-furandicarboxylic acid (FDCA) and intermediates thereof by the chemocatalytic conversion of a furanic oxidation substrate. The present disclosure further provides processes for preparing derivatives of FDCA and FDCA-based polymers. In addition, the present disclosure provides crystalline preparations of FDCA, as well as processes for making the same. |
US10208002B2 |
Modulators of indoleamine 2,3-dioxygenase and methods of using the same
The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. |
US10207988B2 |
Methods and compositions for treatment of cancer and autoimmune disease
The technology described herein relates to methods of inducing cell death. The technology described herein further relates to treating conditions including cancers and autoimmune diseases comprising administering inhibitors of double strand break repair. Also described herein are inhibitors of double strand break repair and methods of screening for such inhibitors. |
US10207987B2 |
Polythiol composition and method for producing same
The present invention provides a polythiol composition containing, as the main component, a polythiol compound (a) having two or more mercapto groups, and containing 0.5% by mass or less of a nitrogen-containing compound (b) in which at least one mercapto group in the polythiol compound (a) is substituted with a group represented by formula (1). |
US10207982B2 |
Solid forms of desvenlafaxine
The present invention refers to new amorphous and crystalline solid forms of desvenlafaxine, also known as O-desmethylvenlafaxine or desmethylvenlafaxine, and to its salts, solvates, hydrates and polymorphs thereof, as well as to their use in the manufacture of a pharmaceutical composition useful in the treatment of depression and/or as a selective serotonin and norepinephrine reuptake inhibitor and also in menopause-associated vasomotor disorders. |
US10207979B2 |
Methods for producing alkyl hydroxyalkanoates
Methods and systems for producing alkyl hydroxyalkanoate from hydroxy carboxylic acid recovery bottoms. The methods generally comprise the steps of obtaining a hydroxy carboxylic acid recovery bottom, adding a mono-alcohol to the hydroxy carboxylic acid recovery bottom to obtain a first mixture, heating the first mixture in the presence of a catalyst to form a reaction product, distilling the reaction product, and recovering an alkyl hydroxyalkanoate fraction. |
US10207975B2 |
Dehydration-hydrolysis processes and catalysts therefor
A process for the co-production of acetic acid and dimethyl ether by contacting methyl acetate and methanol in the presence of catalysts comprising crystalline zeolites having a FER framework type which crystallites have a dimension in the c-axis of about 500 nm or less and a ratio of the c-axis:b-axis dimension of 5:1 or greater and a method for preparation of the zeolites utilizing piperazines. |
US10207973B2 |
Method for producing 1-octanol
The present invention relates to a process for obtaining 1-octanol which comprises a contact step between ethanol, n-hexanol and a catalyst, wherein said catalyst comprises: i) a metal oxide that comprises the following metals: M1 is at least one bivalent metal selected from Mg, Zn, Cu, Co, Mn, Fe, Ni and Ca; M2 is at least one trivalent metal selected from Al, La, Fe, Cr, Mn, Co, Ni, and Ga; ii) a noble metal selected from Pd, Pt, Ru, Rh and Re; and iii) optionally, comprises V; with the proviso that the catalyst comprises at least V, Ga or any of their combinations. |
US10207971B2 |
Compositions comprising 1,1,1,2,3 pentachloropropane
The invention relates to a composition comprising at least 99% by weight of 1,1,1,2,3-pentachloropropane, and comprising at least one compound chosen from a list of additional compounds consisting of trichloropropanes, tetrachloropropanes, pentachloropropanes other than 1,1,1,2,3-pentachloropropane, hexachloropropanes, heptachloropropanes, dichloropropenes, trichloropropenes, tetrachloropropenes, pentachloropropenes and hexachloropropene, said compound being present in the composition in a weight content of less than or equal to 500 ppm.The invention also relates to the use of this composition for manufacturing 2,3,3,3-tetrafluoropropene. |
US10207966B2 |
Process for enhancing the performance of the dehydrogenation of alkanes
A process of catalytically dehydrogenating an alkane to an alkene, using Cr2O3 as a catalyst, where the catalyst is oxidized to CrO3 during the dehydrogenation, and is regenerated by using CO as a reducing gas. In regenerating the catalyst with CO, CO2 is produced, which may be fed to a dehydrogenation reactor with the alkane and reacted with H2 produced by the dehydrogenation, to form CO and H2O by the reverse water-gas shift reaction. |
US10207963B2 |
Catalyst system for olefin oligomerization reaction, and method for olefin oligomerization using the same
Provided are a catalyst system for olefin oligomerization reaction and a method for olefin oligomerization, and more particularly, a catalyst system for olefin oligomerization reaction and a method for olefin oligomerization, which enable more efficient preparation of alpha-olefin, because a catalytic active ingredient is supported on a support, thereby exhibiting high activity in olefin oligomerization reaction even by using smaller amounts of a catalyst composition and a cocatalyst. |
US10207962B2 |
Oligomerization of ethylene to liquid transportation fuels with post synthesis treated ZSM-5 catalyst
A process for post synthesis treatment of ZSM-5 catalyst for converting ethylene to liquid fuel products providing substantially improved catalyst life. The treatment comprises either a base treatment, an acid treatment or a two-step treatment where one is with an acid and the other is with a base. The base treatment is provided by a weak sodium hydroxide such as less than 1 Molar concentration. The acid treatment is stronger acid where, for example, a hydrogen chloride solution at greater than 2 Molar concentration is used. |
US10207957B2 |
Ceramic scintillator and its production method, and scintillator array and radiation detector
A method for producing a ceramic scintillator comprising the steps of mixing a rare earth compound with sulfuric acid and/or sulfate to cause their reaction to obtain a product; calcining the product to obtain calcined powder; reducing the calcined powder to obtain rare earth oxysulfide powder; molding the rare earth oxysulfide powder to obtain a green body; and sintering the green body; a pulverization step being conducted to adjust the particle sizes of the product and/or the calcined powder at least before the reduction step. |
US10207953B2 |
Method to generate high LSG low-emissivity coating with same color after heat treatment
Low emissivity panels can include a separation layer of Zn2SnOx between multiple infrared reflective stacks. The low emissivity panels can also include NiNbTiOx as barrier layer. The low emissivity panels have high light to solar gain, color neutral, together with similar observable color before and after a heat treatment process. |
US10207951B2 |
Window with UV-treated low-E coating and method of making same
Certain embodiments of this invention relates to a coated article including a low-emissivity (low-E) coating supported by a substrate (e.g., glass substrate) for use in a window, where the low-E coating is exposed to ultraviolet (UV) radiation in order to improve the coating's and thus the coated article's electrical, optical and/or thermal blocking properties. The low-E coating includes at least one infrared (IR) reflecting layer of or including silver which is located on and directly contacting a contact/seed layer of or including metal oxide such as zinc oxide and/or zinc stannate. Exposing the low-E coating to UV radiation, e.g., emitted from a UV lamp(s) and/or UV laser(s), allows for selective heating of the contact/seed layer which in turn transfers the heat energy to the adjacent IR reflecting layer. This heating of the silver inclusive layer improves the silver layer's electrical, optical and/or thermal blocking properties. The UV treated coated article, with its improved properties, may be used in the context of monolithic or insulating glass (IG) window units. |
US10207948B2 |
Cordierite glass-ceramic
The present invention relates to an improved cordierite glass-ceramic. In order to improve the materials properties, it is proposed that the glass-ceramic comprising SiO2, Al2O3, MgO and Li2O contains cordierite as main crystal phase and that a secondary crystal phase of the glass-ceramic comprises high-quartz solid solution and/or keatite solid solution. The invention further relates to a process for producing such a glass-ceramic and the use of such a glass-ceramic. |
US10207943B2 |
Methods, compositions and systems for controlling fouling of a membrane
The present invention provides methods and compositions for improving permeability and flux in a membrane filtration system, especially in water or wastewater treatment processes. |
US10207936B2 |
Ultraviolet reactor with planar light source
Various ultraviolet (UV) reactors and their methods of fabrication are disclosed. One exemplary process comprises forming a set of parallel channels in a slab of ultraviolet transparent material. The process also comprises providing a reactor substrate with an input manifold and an output manifold. The process also comprises joining the slab of ultraviolet transparent material and the reactor substrate. The input manifold, output manifold, and set of parallel channels are in fluid communication after the joining step. The process also comprises providing a planar ultraviolet light source isolated from the set of parallel channels by the shaped slab of ultraviolet-transparent material. The set of parallel channels and a defining plane of the planar ultraviolet light source are parallel in the assembled ultraviolet reactor. |
US10207931B2 |
Functionalized reduced graphene oxide and methods of producing the same
Functionalized reduced graphene oxide (functionalized rGO), and a method of producing the same are provided. The functionalized reduced graphene oxide comprises reduced graphene oxide which is fluorinated and co-doped with at least one co-dopant selected from the group consisting of B, N and S. |
US10207928B2 |
Combined membrane-pressure swing adsorption method for recovery of helium
A method of obtaining helium from a process gas. The process gas is at a pressure less than 15 bar to a first membrane separation stage having a first membrane more readily permeable for helium than for at least one other component in the process gas. A first retentate stream is fed to a second membrane separation stage having a second membrane more readily permeable for helium than for at least one other component in the process gas. Helium is separated from a first helium-containing permeate stream using a pressure swing adsorption to obtain a helium-containing product stream. A second helium-containing permeate stream is recycled to the first membrane separation stage. A purge gas from the pressure swing adsorption is also recycled to the first membrane separation stage. |
US10207927B2 |
Method to produce a calibration, reagent or therapeutic gas by exposing a precursor gas to ultraviolet light
The present invention provides a means of producing nitric oxide (NO) by photolysis of nitrous oxide (N2O) at ultraviolet wavelengths. One application is the production of a known concentration of NO in a diluent gas for calibration of analytical instruments that measure nitric oxide in gases such as exhaled breath, ambient air and automobile exhaust. A potentially important medical application is the production of NO for inhalation therapy, an advantage being that very little toxic NO2 gas is produced. The method is useful for producing NO for industrial applications as well. Advantages of this method of NO production include the use of a single, inexpensive, readily available reagent gas of very low toxicity. Furthermore, the concentration of NO produced can be easily controlled by varying the ultraviolet (UV) lamp intensity and relative gas flow rates. The method may also be applied to the production of controlled concentrations of other gases as well such as CO and F2 by using reagent gases other than N2O. |
US10207924B2 |
Method and device for producing syngas
Methods and devices are provided for producing syngas with an adjustable molar CO/H2 ratio. Syngas can have different proportions of CO and H2 (molar CO/H2 ratio) depending on the type and composition of starting materials. To set the desired molar CO/H2 ratio, a first sub-process is combined with at least one additional sub-process selected from: a sub-process T2 by which a second syngas B is generated from the starting material, the syngas having a molar ratio (V2) of CO to H2, wherein V1≠V2; a sub-process T3 by which the hydrocarbon(s) of the hydrocarbon-containing starting material is/are split substantially into solid carbon and hydrogen; and a sub-process T4 based on the reaction equation: CO+H2O→2CO2+H2. The methods and devices are suitable for producing syngas useful as a starting material in a plurality of chemical syntheses, for example oxo, Fischer-Tropsch, or Reppe syntheses. |
US10207919B2 |
Hybrid nanoparticles containing dendrons, methods of producing such hybrid nanoparticles, and uses thereof
The present disclosure relates to a hybrid nanoparticle comprising a metallic core and at least one lipophilic dendron attached to the surface of the metallic core, and methods of producing such hybrid nanoparticles. The present disclosure also relates to films containing the hybrid nanoparticles described herein. |
US10207918B2 |
Electromechanical transducer and method for manufacturing the same which suppresses lowering of sensitivity while a protective layer is formed
An electromechanical transducer of the present invention includes a first electrode, a vibrating membrane formed above the first electrode through a gap, a second electrode formed on the vibrating membrane, and an insulating protective layer formed on a surface of the second electrode side. A region where the protective layer is not formed is present on at least part of a surface of the vibrating membrane. |
US10207914B2 |
Electronic vaporiser system
An electronic cigarette vaporizer is not dis-assembled for filling with e-liquid, but is instead filled from a user-replaceable e-liquid cartridge. The vaporizer includes a front section comprising a wick and heating assembly but no e-liquid cartridge, the front section being removably fitted to a body of the vaporizer to enable a replacement front section to be used once the original wick or heating element starts to degrade, that replacement front section being supplied to the end-user with no e-liquid in it. |
US10207909B2 |
Rotary filling apparatus and methods
Embodiments of the invention include apparatus for filling containers and related methods. In an embodiment, an apparatus includes a rotary turret assembly rotatably coupled to a filler frame. The rotary turret assembly can include a rotary base and a plurality of hollow columns mounted on the rotary base and arranged in a circle. A plurality of piston assemblies can be configured to move up and down within the hollow columns. Each piston assembly can include a piston body and a top hat assembly configured to releasably engage the top of the piston body. The piston body and the top hat assembly can release from one another when a release lever is engaged. Rotation of the rotary column group causes the cam contact members of the piston assemblies to move over a surface of a cam track causing vertical movement of the top hat assemblies. Other embodiments are included herein. |
US10207907B1 |
High visibility load clamp with asymmetrical gussets
An asymmetrical gusseted clamp assembly configured to be coupled to a lift truck and comprising a frame, two clamp jaws and two actuators. The clamp jaws each have gussets of different size to allow the two actuators to be separated vertically by a central gap, which is defined on the sides by two frame vertical beams. The central gap is of significant width so that the operator of the lift truck has a useable widow through which to view. As the configuration of the asymmetrical gusseted clamp assembly changes from open to closed, at no time is a majority of the view through the central gap obscured by the clamp jaws. |
US10207906B2 |
Lifting assembly for a lift truck, and lift truck
A lifting assembly for a lift truck with a lifting mast having at least one mast frame and a load part, as well as a lift drive having at least one lifting chain that lifts the mast frame, is attached to the mast frame at a connecting point and is guided across a deflection point. The lifting assembly includes at least one tensioning component that is arranged on the mast frame between the connecting point and deflection point of the lifting chain. |
US10207904B2 |
Crane, particularly crawler crane or mobile crane
The invention relates to a [crane], particularly crawler crane or mobile crane, with at least one monitoring and simulation means, by means of which a state of the crane can be monitored and/or simulated, wherein the monitoring and simulation means comprise at least one input means and at least one output means, and wherein, by means of the monitoring and simulation means, the change in state, particularly the bearing load curve of the crane, and particularly also the movement of the crane and/or of the boom of the crane, can be represented at any time, and/or a possible state and/or a possible change in state of the crane, particularly the bearing load curve of the crane, can be simulated and/or represented. |
US10207902B2 |
Load-mountable lift eye assembly
Exemplary embodiments of a load-mountable lift eye assembly comprise a connection interface, a mounting coupler and an axial retention element. A bushing may be disposed radially between the mounting coupler and a mounting bore of the connection interface. The axial retention element may engage the mounting bore so as to retain a segment of a head portion of the mounting coupler between a shoulder flange of the mounting bore and the axial retention element, thereby retaining the mounting coupler in mounting position and limiting its ability to move axially with respect to the connection interface. The mounting coupler may include a head-shaft interface. In such case, when the mounting coupler is in its mounting position, the head-shaft interface may be axially offset from the mounting face of the connection interface. The mounting coupler may include a tool-engagement section adapted to be engaged by one or more types of torqueing tools. |
US10207895B2 |
Elevator emergency power feeder balancing
A system and method of balancing elevator car emergency power in an elevator system is provided. The method includes switching a first feeder group of elevator cars from building power provided through a first building power feeder to back-up power provided through a back-up power source, switching a second feeder group of elevator cars from the building power provided through a second building power feeder to the back-up power provided through the back-up power source, selecting, using an elevator controller, at least one elevator car from the first feeder group of elevator cars, selecting, using the elevator controller, at least one elevator car from the second feeder group of elevator cars, and powering the selected elevator cars from the first feeder group and the second feeder group using the back-up power from the back-up power source. |
US10207894B2 |
Controlling sway of elevator cable with movement of elevator car
An elevator system includes an elevator car supported by an elevator rope wrapped around a sheave, such that a rotation of the sheave changes a length of the elevator rope between the sheave and the elevator car thereby controlling a movement of the elevator car within an elevator shaft of the elevator system. An elevator cable is connected to the elevator car and the elevator shaft to carry electrical signals to the elevator car. The operation of the elevator system is controlled in response to receiving a call for a movement of the elevator car requesting a change of the length of the elevator rope. A motion profile of the elevator car causing the requested change of the length of the elevator rope that minimizes the sway of the cable is determined according to a model of a cable relating a sway of the cable to a motion profile. Next, the motion of the elevator car is controlled according to the determined motion profile. |
US10207893B2 |
Elevator call allocation and transmission based on a determination of walker speed
The invention relates to a method and apparatus. In the method a determining a first position of a user of a mobile node is determined at a first time instant. A second position of the user of the mobile node is determined at a second time instant. A time difference is determined between the first time instant and the second time instant. A walking speed of the user is determined using the time difference, the first position and the second position. A third position of the user of the mobile node is determined. A walking time required for the user to reach at least one elevator is determined from the third position based on the walking speed of the user. An elevator call and the walking time are transmitted to an elevator call control node. |
US10207889B2 |
Image processing apparatus and sheet transport method
An image processing system includes an image forming unit, an image decoloring unit, a first sheet stacking unit, a second sheet stacking unit, a first detector for the first sheet stacking unit, a second detector for the second sheet stacking unit, and a control unit. The control unit controls a transport path of a sheet discharged from one of the image forming unit and the image decoloring unit. |
US10207884B2 |
Image forming apparatus
An image forming apparatus, including a reference guide, an oblique conveyer roller, and a curve guide, is provided. The reference guide is arranged on one side in a widthwise direction with respect to a widthwise center in a sheet conveyer path and regulates a widthwise position of the sheet. The oblique conveyer roller applies a conveying force acting in a direction toward downstream along a conveying direction and toward the reference guide to the sheet. The curve guide is arranged upstream with respect to the oblique conveyer roller along the conveying direction and forms a curve. The curve guide includes an inner guide and an outer guide. The outer guide has a constant curvature throughout a width regardless of a widthwise position therein. The inner guide has a protrusive portion protruding toward the outer guide at a position on the other side in the widthwise direction with respect to the widthwise center. |
US10207879B2 |
Method and apparatus for honing a workpiece
A honing machine using a robot to load gears into a loadbox at a loadbox station. The loadbox moves downstream to a position over an empty pallet in a pallet load station where the gears are released into the empty pallet. A series of downstream machining stations performing a series of honing operations on the bores of the gears in a series of pallets. A removal mechanism removing the honed gears simultaneously from the pallet at a pallet unload station. An overhead gripper on a movable gantry grips the empty pallet at the unload station and returns the pallet to the pallet load station where the pallet is reloaded with additional gears from the loadbox. The honing machine can continuously hone gears using only one pallet at each machining station and one pallet at the pallet loading station. |
US10207877B2 |
Guard device for transport bags in a loading station of an overhead conveyor system and loading station comprising a guard device of this type
A guard device for transport bags in a loading station of an overhead conveyor system comprises a mounting unit to mount the guard device to a conveyor device of the overhead conveyor system, an impact plate to support a rear wall of a transport bag when being loaded with a product to be transported, and a connection unit to movably connect the impact plate to the mounting unit. |
US10207872B2 |
Workpiece conveyor system
A workpiece conveyor system comprising: a conveyance apparatus which conveys workpieces in one direction, a stopper which is mounted on the conveyance apparatus so as to stop workpieces which are conveyed by the conveyance apparatus at a predetermined position, and a takeout apparatus which takes out workpieces which have been stopped by the stopper from the conveyance apparatus. An outer edge of the stopper in an opposite direction to a conveyance direction of workpieces extends in a curved shape in a transverse direction of the conveyance apparatus. |
US10207871B2 |
Storage and order-picking system
It is disclosed a method (70) for operating a storage and order-picking system (10) in which a plurality of manipulators (40) process a plurality of picking/storing orders in accordance with a manipulator-to-handling-unit principle, wherein the system (10) comprises a provision zone (12), a picking zone (14), a plurality of provision units (42, 62) in the provision zone, a plurality of, particularly stationary arranged, transfer locations (46) in the picking zone (14), a DTS (18) including a plurality of DTVs (20), and a controlling device (32), and wherein the method (70) comprises the following steps of: analyzing (S10) the plurality of picking/storing orders by the controlling device (32) for determining retrieval/delivery locations in the provision zone (12); setting (S12) of transfer actions (48) by selecting for each of the retrieval/delivery locations one or more of the transfer locations (46) in the picking zone (14) as delivery/retrieval location and by assigning the same thereto, wherein the delivery/retrieval location is located within an action zone (72) extending around the respective retrieval/delivery location and moving dynamically with the respective manipulator (40); generating (S14) an action order for each of the manipulators (40) by selecting some of the transfer actions (48), and setting a, particularly unidirectional, moving path (74) along which the respective manipulator (40) moves between the selected retrieval/delivery locations throughout the, preferably entire, picking zone (14); and generating (S16) transport orders for the DTVs (20) so that each of the manipulators (40), during performance of its action order, can perform its transfer actions (48) within its action zone (72), preferably without interruption. |
US10207868B1 |
Variable compliance EOAT for optimization of GCU
Described herein is an inventory management system and methods of operating a robotic arm assembly in which the level of compliance of the robotic arm assembly is altered in order to achieve a high gross cubic utilization. In at least some embodiments, a robotic arm assembly may adopt a low level of compliance when grasping an item. The inventory management system may identify an appropriate storage location for the item and move the item to that storage location. Upon reaching the storage location, the robotic arm assembly may adopt a higher level of compliance. The robotic arm assembly may then push the item against one or more other items in order to insert the item into the determined storage location. |
US10207866B1 |
Load monitoring system using acceleration of the vehicle for waste service vehicle
A system is disclosed for monitoring waste collected by a service vehicle. The system may include a sensor configured to generate an acceleration signal indicative of an acceleration of the service vehicle, an output device, and a controller in communication with the sensor and the output device. The controller may be configured to receive the acceleration signal from the sensor after collection of the waste from a service stop. The controller may be further configured to determine an amount of the waste collected by the service vehicle from the service stop based on the acceleration signal, and to relay the amount of the waste to the output device. |
US10207859B2 |
Nutritional substance label system for adaptive conditioning
Disclosed herein are nutritional substance labels that communicate in a format allowing retrieval of adaptive conditioning instructions unique to an individual nutritional product at the time of conditioning and intended to optimize a nutritional, organoleptic, or aesthetic value targeted by the transformer. |
US10207855B2 |
Arrowhead novelty caddy
The present invention is a arrowhead novelty caddy. The present invention provides a effective storage of items and a method for attachment(s). In particular, the present invention can be pinned to caps, hats, backpacks, or just about anything that comes to mind; and, the present invention can be placed and held on a magnetically metal surface, such as a refrigerator or in areas where there is a magnetic metal surface. In particular, the present invention provides a user easy access to items. |
US10207853B2 |
Oxygen scavengers
Described herein are oxygen scavengers, oxygen scavenging polymeric compositions, and oxygen scavenging articles. The polymeric compositions comprising the oxygen scavengers may have utility in packaging, sealing, wrapping, and storing oxygen-sensitive substances, e.g., to preserve freshness of foods, beverages, and the like. |
US10207851B1 |
Insulating container with interlocking panels
Disclosed are various embodiments for a container that comprises multiple interlocking panels. According to various embodiments, a first panel includes a first notch, a second notch, a third notch, and a fourth notch. A second panel includes a first tab that is configured to be inserted into the first notch of the first panel. A third panel includes a second tab that is configured to be inserted into the second notch of the first panel. A fourth panel includes a third tab that is configured to be inserted into the third notch of the first panel. A fifth panel includes a fourth tab that is configured to be inserted into the fourth notch of the first panel. |
US10207848B2 |
Carton with article protection insert
A carton for containing at least one article. The carton comprises a plurality of panels at least partially forming an interior of the carton. The plurality of panels comprises a top panel. The carton comprises an article protection flap foldably connected to at least one panel of the plurality of panels. The article protection flap is moveable between a first position that is substantially parallel to the top panel and a second position wherein the article protection flap is folded relative to the top panel. The at least one access feature in the top panel is for positioning the article protection flap from the first position to the second position. |
US10207844B2 |
Dropper
A package includes a container and a lid. The container includes a body formed to include an interior product-storage region and neck coupled to the body and formed to include a mouth opening into the interior-product storage region. The lid is coupled the neck of the container and formed to include a portion of a droplet passageway therein which is arranged to extend along a longitudinal axis of the lid. The droplet passageway is adapted to communicate a droplet of fluid from the interior region to environment surrounding the package. |
US10207843B2 |
Container stopper having multi-lock structure
The present invention relates to a container stopper having a multi-lock structure in which a multi-lock structure is applied to the inner circumferential surface of an opening of a lower stopper, and to the outer circumferential surface of a sealing protrusion of an upper stopper coupled thereto, thereby preventing the coupled stoppers from being easily opened due to shock or other external force generated during the distribution process or storage of a product. To this end, the present invention provides a container stopper comprising: a lower stopper (110) which is coupled to an inlet (10) of a container (10); and an upper stopper (120) which allows an opening (111) provided within the lower stopper (110) to be selectively opened and closed, wherein at least two locking parts (130) are formed so as to be spaced apart from each other in the insertion direction on the inner circumferential surface of the opening (111) of the lower stopper (110) and on the outer circumferential surface of a sealing protrusion (121) of the upper stopper (120) coupled to the inner circumferential surface. The present invention as described above has the advantages of allowing the main locking position of the upper stopper coupled to the opening of the lower stopper to be formed so as to be inclined toward the end side of the sealing protrusion, thereby preventing the upper stopper from being easily opened by external shock, and also of improving the assembly strength of the upper stopper by applying the position of the locking parts to at least two points on the outer circumferential surface of the sealing protrusion. |
US10207838B1 |
Cornerpost support
A packaging insert formed from a one-piece blank including a main body panel having opposing first and second longitudinal edges and opposing first and second lateral edges. The folded blank further includes a pair of column panels, each column panel including a first side panel, a front panel, a second side panel, and an overlap tab connected to the lateral edges of the main body panel in series at first, second, third, and fourth lateral score lines. The front panel of each column panel is folded about a respective second lateral score line with the overlap tab overlapping and attached to the main body panel. Each column panel can be erected to form a rectangular column adjacent to each of the lateral edges of the main body panel. |
US10207837B2 |
Method and device for labeling packages and containers
A method and device for labeling packages and containers. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. § 1.72(b). As stated in 37 C.F.R. § 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner. |
US10207836B2 |
Foldable bag support sleeve
A foldable support sleeve that is deployable inside of a waste bag to support the waste bag includes a first side foldably connected to a second side, the second side foldably connected to a third side, the third side foldably connected to a fourth side, and the fourth side foldably connected to a fifth side. The foldable support sleeve may be foldable into a pre-deployed state and into a deployed state. The pre-deployed state may be associated with a first cross section that is smaller than a second cross section associated with the deployed state. The second cross section may be approximately equal to a cross section associated with the waste bag. The fifth side may help retain the foldable support sleeve in the deployed state. |
US10207835B2 |
Capping machine in a beverage bottling plant configures to cap beverage bottles with beverage bottle crown caps or beverage bottle screw caps and a capping machine configured to cap containers with container caps
A capping machine in a beverage bottling plant configured to cap beverage bottles with beverage bottle crown caps or beverage bottle screw caps and a capping machine configured to cap containers with container caps. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. § 1.72(b). As stated in 37 C.F.R. § 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner. |
US10207833B2 |
Packaging container and packaging method using the same
The invention provides a packaging container for plate shaped articles and a packaging method using the same. The packaging container comprises a container sole plate, a container lid plate and container side plates. Each of them is provided with detachable assembling parts which allow the container sole plate, the container lid plate and container side plates to be detachably assembled to form the packaging container. The arrangement of detachable assembling parts on the container sole, the container lid and the container side plates may realize the detachable assembly among them. That is, any side of the cubic packaging container can be separately detached during the packaging operation, such that it is possible to more easily and promptly package or obtain the plate shaped articles, while the plate shaped articles are hardly to be damaged when being packaged, thereby fulfilling the demand on automatic packaging for plate shaped articles. |
US10207829B2 |
Funnel component and manufacturing method for manufacturing packaging container using funnel component
A funnel component is manufactured by the following processes: forming a first intermediate product that is tapered, by rolling the blank material; forming a second intermediate product by folding back and welding a narrow opening side portion of the first intermediate product; forming a third intermediate product having the side wall portion by folding the wide opening side portion of the second intermediate product back outward; forming a cylindrical discharge portion forming the narrow opening side portion, a first tapered portion that connects to the discharge portion and has a tapered shape, and a second tapered portion that has a tapered shape having a taper angle less than the first tapered portion, by performing a drawing process on the third intermediate product. |
US10207828B1 |
Attachment assembly between a rotating structure and a stationary structure for a habitation module
A habitation module that provides an artificial gravity environment. In one embodiment, the habitation module includes a rotating structure configured to rotate about an axis in relation to a stationary structure, and attachment assemblies configured to rotatably couple the rotating structure to the stationary structure. The attachment assemblies comprise bearings installed coaxially between a cylindrical housing of the rotating structure and a cylindrical body member of the stationary structure, and dynamic radial seals installed coaxially between the cylindrical housing and the cylindrical body member. The attachment assemblies further comprise a static seal assembly that includes an end cap movable between a locked position and an unlocked position. |
US10207827B2 |
Artificial gravity system having gravity chambers with rigid side walls that are extendible
A habitation module that provides an artificial gravity environment. In one embodiment, the habitation module includes a rotating structure that rotates about an axis in relation to a stationary structure. The rotating structure includes a first gravity chamber that projects radially from the rotating structure, and a second gravity chamber that projects radially from the rotating structure in an opposite direction than the first gravity chamber. The first gravity chamber and the second gravity chamber are each comprised of a plurality of ring members that form side walls of the first gravity chamber and the second gravity chamber. The ring members are concentric so that the side walls of the first gravity chamber and the second gravity chamber radially extend and radially contract in upon themselves. |
US10207824B2 |
Radiator deployable for a satellite stabilized on three axes
A photovoltaic generator deployable for a satellite stabilized on three axes. The photovoltaic generator includes an assembly of planar panels articulated with respect to each other, and an attachment arm to the structure of the body of the satellite. In a first or launch position of the photovoltaic generator, the planar panels are folded one over the other. In a second or deployed position of the photovoltaic generator, the planar panels are fully deployed with at least a part of the planar panels being photovoltaic panels. At least one planar panel consists of a thermal radiator, with the radiative face thereof being orientated to be opposite the face of the photovoltaic panels carrying the photovoltaic sensors when the photovoltaic generator is in the deployed position. This radiative face is termed the “shade” face, and the face opposite the panel shaped radiator is termed the “sun” face. |
US10207823B2 |
Deployable assembly
A deployable assembly comprises a supporting structure, a set of panels, each being linked to the adjacent panel by a hinge defining an intermediate axis of rotation, capable of switching from a stowed configuration in which the panels are folded one on top of the other to a deployed configuration, by rotation of the panels about the respective intermediate axes of rotation, wherein the panels are arranged substantially in the same plane, an articulation device defining a main axis of rotation of the set of panels relative to the supporting structure. The set of panels is rotationally mobile about the intermediate axes of rotation and the main axis of rotation to switch from the stowed configuration to the deployed configuration and the set of panels is only rotationally mobile about the main axis of rotation in deployed configuration to orient the set of panels relative to the supporting structure. |
US10207822B2 |
Test module fixture for aerial vehicle module
A fixture is provided for securing an annular drone module to a test stand. The fixture includes a rear outside annulus, a front inside annulus, a plurality of tabs, and a plurality of flanges. The rear outside annulus extend radially to an outer rim and longitudinally from an aft surface and a lip surface. The front inside annulus extends radially to a mezzanine rim and longitudinally from the lip surface to a fore surface. The tabs extending radially from the mezzanine rim on the front inside annulus. The plurality of flanges extending from the outer rim on the rear outside annulus. The drone module is disposed facing the lip surface between the tabs and the mezzanine rim by first mechanical fasteners, and the flanges mount to the test stand by second mechanical fasteners, such as screws. The fixture can be a unitary construction and be composed of thermoset plastic. |
US10207821B2 |
Coupling module with a position sensor
A coupling module for coupling a passenger boarding bridge with an aircraft has a floor assembly and a canopy roof spanning the floor assembly. The coupling module and/or the floor assembly is configured to be received at a cabin of a passenger boarding bridge such that the coupling module and/or the floor assembly can swivel relative to the cabin around a horizontal swivel axis. A position sensor is operable to measure an inclination of the floor assembly relative to a geodetic horizontal position. |
US10207818B2 |
Method and system for displaying the external environment of an aircraft, and aircraft door equipped with such a system
A system and method for displaying the external environment of the airplane. The system includes a camera mounted on the door of the airplane. The camera having lens for capturing the external environment illuminated by a illumination source in order to provide a video signal, and at least one display screen connected with the camera for receiving the video signal. |
US10207817B2 |
Static discharger, aircraft and installation process for the static discharger
The present invention relates to a static discharger, an aircraft, and an installation process for the static discharger. According to an aspect of the present invention, a static discharger is provided which includes: a basement; and a discharger body installed to the basement. An installation orientation adjusting mechanism is provided between the basement and the discharger body, and the installation orientation adjusting mechanism allows the discharger body to be rotationally orientated, with respect to the basement, to a predetermined installation orientation during an on-site-installation of the static discharger. The static discharger further includes a first fixing mechanism adapted to fix the discharger body, which has been oriented to the predetermined installation orientation, to the basement. According to the present invention, for example, installation adaptation and universality of the static discharger and adjustment and determination of installation orientation of the static discharger can be improved. |
US10207816B1 |
Aerially dispersible massively distributed sensorlet system
A distributed sensor module system comprises a plurality of sensor modules configured to be aerially deployable from a deployment device, the deployment device including an unmanned aerial vehicle (UAV) or an aeronautically deployable unitized container, the plurality of sensor modules configured to communicate with each other. A first sensor module comprises a first sensor configured to obtain first sensor information from a first environment proximate to the first sensor, a processor coupled to the first sensor, the processor configured to process the first sensor information to obtain locally processed first sensor information, and a communication transceiver coupled to the processor, the communication transceiver configured to communicate the locally processed first sensor information to a second sensor module, the first sensor module and the second sensor module configured to be aerially deployable. |
US10207814B2 |
Ram air turbine cooling inlet screen heating system
A heating system for a ram air turbine includes a heated screen that is disposed across an air inlet defined by a strut. The strut has a first end that is connected to a generator that is operably connected to a turbine that is connected to a second end of the strut. The heated screen has a heating element embedded therein. |
US10207813B1 |
Regenerative activated carbon filtration for aircraft obiggs
An onboard aircraft inerting system includes an apparatus and method for regenerating an activated carbon media of a filter module while the aircraft is in flight. In regeneration mode, the activated carbon media is heated to a temperature sufficient to desorb the VOC contaminants adsorbed thereon and the air stream passing through the filter module is at a pressure lower than the air pressure of the air stream passing through the filter in normal inerting mode. |
US10207804B1 |
Temperature-controlled payload container
A temperature-controlled payload container that may be used by an unmanned aerial vehicle (UAV) to transport perishable items and/or items desired to be at or near a specific temperature upon arrival at a destination. The temperature-controlled payload container may be used to maintain or adjust a temperature of a delivery item, such as a food item. In some embodiments, the temperature-controlled payload container may be capable of heating items in a first portion of the container and cooling items in a second portion of the container. For example, the container may be divided by a Peltier junction, which is an electrified junction of two different conductors. In some embodiments, the temperature-controlled payload container may receive heat generated from operation of the UAV. |
US10207803B2 |
Package delivery and reception with drones
A computer program product for automatically delivering a physical mail includes receiving, by an unmanned aerial vehicle from an unmanned aerial vehicle management system, a delivery information, the delivery information includes information about a first secure mailbox and information about a second secure mailbox, the first secure mailbox being related to a first target user, delivering the physical mail to the first secure mailbox, and rerouting the unmanned aerial vehicle carrying the physical mail from the first secure mailbox to the second secure mailbox in response to the physical mail being delivered to the first secure mailbox. |
US10207801B2 |
Inspecting a solar panel using an unmanned aerial vehicle
A method for inspecting a solar panel of a solar power station is performed in a controller for an unmanned aerial vehicle, UAV, and includes the steps of: receiving an inspection request for a subset of the solar panels navigating, in a first stage, using radio signals, the UAV to an initial location in a vicinity of a particular solar panel of the subset of solar panels; positioning, in a second stage, the UAV using at least one near field sensor of the UAV; and capturing, using the infrared camera, an image of the particular solar panel. |
US10207800B2 |
Helicopter anti-torque rotor
An anti-torque rotor of a helicopter, having: a supporting body; a drive shaft which rotates about a first axis with respect to the supporting body; a hub connected operatively to drive shaft and angularly fixed with respect to first axis; at least one blade which is connected operatively to hub, is angularly fixed with respect to first axis, and is angularly movable with respect to a second axis to adjust the pitch angle of blade; and an actuator which can be operated to rotate blade about second axis to adjust the pitch angle of blade; actuator has an electric motor which generates torque along the first axis; and a mechanical stage interposed between the electric motor and blade, and designed to convert the torque into rotation of blade about the respective second axes; electric motor is fixed to supporting body. |
US10207793B2 |
Rotor blade having variable twist
A rotor blade including a root portion adapted to be connected to a helicopter rotor hub for rotation therewith, the root portion having a first edge surface; a first movable member having a first movable surface adjacent to the first edge surface; a first elastomeric joint disposed between the root portion and the first movable member, the first elastomeric joint having an inner surface facing the first edge surface of the root portion and an outer surface facing the movable surface of the first movable member; and an actuating system mounted within the root portion and the first movable member for moving the first movable member. The first elastomeric joint deforms to adjust for shear from actuation of the first movable member to a first position during helicopter mode; and to a second position during airplane mode. |
US10207789B2 |
Aircraft composite wingbox integration
Systems and methods are provided for integrating structural components of a wing box. One embodiment is a system that includes outboard planked stringers within an outboard section of a wing box and are co-cured with composite skin at the outboard section. Each outboard planked stringer of the outboard section includes planar layers of Carbon Fiber Reinforced Polymer (CFRP) that are parallel with the composite skin at the outboard section, have fiber orientations aligned to bear tension and compression applied to the wing box, and each extend a different distance along the composite skin at the outboard section. The system also includes center planked stringers within the center section and are co-cured with composite skin at the center section. Each center planked stringer of the center section includes planar layers of CFRP that are parallel with the composite skin at the center section, have fiber orientations aligned to bear tension and compression applied to the wing box, and each extend a different distance along the skin at the center section. |
US10207784B2 |
Center pivot adjustable oarlock
The invention relates to a center-axis oarlock and methods of providing constant gearing throughout the arc of an oar in a boat or shell. |
US10207783B1 |
Paddleboard kit
The invention involves a paddleboard kit for converting any water sports board such as a surfboard into a paddleboard. An oar support assembly, typically secures oars with pivotal paddles to the board; facilitating rowing exercises that may be practiced while kneeling or standing. During use, the pivotable paddles pivot in such a way that the blade portion holds a steady position in relation to a shaft portion on the power stroke, while being free to fold in the opposite sense on the idle stroke when each stroke is executed as a substantially axial thrust of the shaft. The oar support assembly secures the pair of oars and is itself secured to the board by way of board couplers adjustably coupled to a portion of a strap that tightens to snuggly wrap around the board. |
US10207778B1 |
Wake tower apparatus and method of making same
A wake tower assembly for use with a watercraft, including an arch portion extending across a width of the watercraft, first and second pivoting structures coupled to first and second ends of the arch portion, the first and second pivoting structures configured to attach to port and starboard portions of the watercraft to facilitate rotational movement of the arch portion between a lowered position and an upright position, and a first locking mechanism provided to the first pivoting structure including a biased pin member configured to engage an opening of the first end such that when the arch portion is rotated from the lowered position to the upright position, a biasing force of the biased pin member causes the biased pin member to engage the opening to mechanically lock the arch portion in the upright position. |
US10207774B2 |
Systems and methods for heating oil stored in an offshore vessel or production platform
A offshore system for storing oil includes a hull. The hull includes a buoyancy compartment and an oil storage compartment disposed below the buoyancy compartment. The oil storage compartment has an upper end, a lower end, and an inner cavity. In addition the system includes a water port in fluid communication with the inner cavity and configured to allow water to exit the inner cavity. Further, the system includes an oil heating and circulation system coupled to the hull. The oil heating and circulation system includes a suction line having an inlet disposed in the inner cavity proximal the upper end. The inlet is configured to draw oil from the inner cavity. The oil heating and circulation system also includes an oil heater coupled to the suction line and configured to heat oil passing through the suction line. Further, the system includes a return line coupled to the oil heater. The return line includes an outlet disposed in the inner cavity and vertically positioned between the inlet of the suction line and the water port. |
US10207772B2 |
Gear transmission and derailleur system
A transmission system for vehicles, including bicycles, is disclosed. The system aligns a chain or other drive means to a center of each of a plurality of provided sprockets, allows for a smaller, lighter and more durable shifter/controller, and reduces various complications associated with cable slack and shifting. A derailleur is provided with linear actuated features to directly translate drive means from one position to another along a desired path. |
US10207768B2 |
Bicycle operating device
A bicycle operating device is provided with a support structure, a release member, a first operating member and a release pawl. The release member is pivotally supported on the support structure to pivot about a pivot axis between a first non-releasing position and a first releasing position. The first operating member is movably supported on the support structure between a rest position and an operated position. The release pawl is movably mounted on the first operating member. The release member includes a first abutment and a second abutment. The second abutment is circumferentially spaced from the first abutment with respect to the pivot axis. The release pawl is selectively arranged to engage one of the first and second abutments, and pivot the release member during movement of the first operating member from the rest position towards the operated position without engaging the other of the first and second abutments. |
US10207767B2 |
Bicycle rim brake
Responsive to a hydraulic piston advancing out of a piston housing in a second brake arm and contacting a piston cam surface of a first brake arm, the second brake arm pivots around a second pivot. As this is happening, a cam surface in the second brake arm lifts a contact surface of a first force transfer member of the first brake arm, imparting torque to the first brake arm which then pivots around a first pivot. The cam surface is shaped to impart synchronous motion to the first and second pad holders. Splitting one of the brake arms with a centering member permits a centering adjust feature. |
US10207764B2 |
Battery safety enclosure
A battery safety enclosure is provided that contains a battery pack and is attached to a vehicle with a frame. The enclosure has a flat surface that is close to and overlays a flat surface on the frame. The flat surface includes a vent port that is covered by a plug. If the battery pack should fail and release gas, the plug separates from the vent port and pressure is released in a controlled fashion. The flat surface of the enclosure further contains release channels that are recessed from the flat surface on the enclosure. The release channels slow and disperse the release of flammable gas. The safety enclosure may contain a control circuit board that controls the charging and discharging of the battery. |
US10207763B2 |
Usage detection system for a self-balancing powered unicycle device
A usage detection system for a self-balancing powered unicycle is disclosed. The usage detection system is adapted to detect an indication of intended usage from a user and to provide an indication of intended usage. The indication of intended usage comprises manipulation of the overall unicycle device resulting from preparatory action taken by the user prior to the onset of the intended usage. Operation of the powered unicycle may thus be controlled based on an indication of intended usage from the usage detection system. |
US10207762B2 |
Mobile body
A control device (60) of a mobile body (1) calculates a center-of-gravity displacement degree index value representing an estimate of the degree of displacement of the center of gravity of the operator in the lateral direction of a vehicle body (2) from a predetermined reference position with respect to the vehicle body (2), and determines a control input for an actuator (15), which can cause a moment in the roll direction to act on the vehicle body (2), so as to increase the degree of displacement of the center of gravity of the operator indicated by the center-of-gravity displacement degree index value in a state of presence of such displacement. The control device (60) controls the actuator (15) in accordance with the control input. |
US10207759B2 |
Detachable multimedia control apparatus
The present invention provides a detachable multimedia control apparatus, comprising: a front housing structure including a left turn signal, a right turn signal and a central light; a rear housing structure including a speaker module and a safety switch module; a top housing structure including a control module which controls the speaker module and the central light; a bottom housing structure including a first joining structure; a processor disposed inside the movable multimedia control apparatus and electrically connected to the left turn signal, the right turn signal, the central light, the speaker module, the safety switch signal and the control module; and a power module disposed inside the detachable multimedia control apparatus and electrically connected to the left turn signal, the right turn signal, the central light, the speaker module, and the processor, wherein the power module is configured to be unlocked by the safety switch module. |
US10207753B2 |
Trailer for hauling unit load devices
A trailer for carrying unit load devices (ULDs), including unloaded and/or loaded containers and pallets, or other cargo; the trailer designed to be towed on surface streets and highways by conventional motorized truck-tractor units. The trailers are equipped with adjustable decks for supporting ULDs in stacked configuration on the trailer. Using a lowered well portion permits selected ULD stacks to not exceed legal trailer height limits so that additional permitting is not required. |
US10207750B2 |
Vehicle
A vehicle in which separation of airflow from a vehicle surface can be prevented without causing disfigurement is provided. A vehicle body is insulated from a road surface, and positive static charges accumulate on the vehicle body during propulsion. The vehicle comprises a charge control device adapted to decrease the positive potential of a separation point at which positively charged airflow flowing along a vehicle surface deviates from the vehicle surface during propulsion by applying negative ions to an inner surface of the separation point. |
US10207749B2 |
Polymeric engine hood assembly, vehicle front end module, vehicles comprising the same and methods of making the same
A method of making a polymeric engine hood assembly for use in a vehicle can include applying heat to a first polymeric sheet, applying heat to a second polymeric sheet, stacking the first polymeric sheet and the second polymeric sheet, placing the stacked sheets between a first mold half and a second mold half, closing the first mold half and second mold half, applying vacuum to the space between the first polymeric sheet and the first mold half and between the second polymeric sheet and the second mold half, wherein the first polymeric sheet forms an exterior panel and wherein the second polymeric sheet forms a reinforcing structure; and attaching an exterior panel to a fender skin at a junction surface, wherein the reinforcing structure includes a connecting ridge extending transversely across the reinforcing structure, wherein the connecting ridge is configured to accept the junction surface of the exterior panel and the feeder skin. |
US10207746B2 |
Vehicle floor pan
A floor pan assembly is disclosed that includes a side sill extending in a longitudinal direction that has a lower portion and a top surface. The floor pan may include a weld flange having a height H1 that is welded to the lower portion along a full length of the floor pan and an extended weld flange having a height H2 that is higher than H1 and welded to the top surface of the side sill along a limited length of the floor pan. The floor pan may also include a corrugated area integrally provided in the floor pan that includes a plurality of furrows and ridges that extend obliquely relative to the longitudinal direction. |
US10207742B2 |
Vehicle structure and manufacturing method for vehicle structural component
A vehicle structure includes: a framework member; an outer panel disposed at the outer side of the framework member, and that configures a design face of the vehicle; a foamed member disposed as a reinforcing material between the framework member and the outer panel, and that is formed from a material foamed at a first temperature from a precursor state and then solidifies at a second temperature lower than the first temperature; and a reinforcement member that is interposed between the outer panel and the foamed member in a state in which the outer panel and the foamed member are respectively joined together so as to fix the foamed member to the outer panel, and that is configured from a material having a smaller shrinkage ratio than a shrinkage ratio of the foamed member when the temperature is lowered from the first temperature to the second temperature. |
US10207737B2 |
Fabricated steering knuckles
A steering knuckle (18) is provided for use in association with a vehicle steering assembly (10). The steering knuckle (10) includes a knuckle body (20) having a generally vertical face (26) and an upper yolk arm (22) having a generally vertical face (54). The generally vertical faces (26, 54) of the steering knuckle body (20) and the upper yolk arm (22) are connected to each other. The generally vertical face (54) of the upper yolk arm (22) includes a camshaft bore (62) extending therethrough and configured to receive a camshaft (64). The generally vertical face of the knuckle body may be welded to a spindle (24), with a portion of the spindle being cut away to allow for a complete circular weld between the knuckle body and the spindle. |
US10207736B2 |
Steering control device for working vehicle
A steering control device (20) for a working vehicle includes an electric motor device (34) that generates an assistance torque to a steering column (33), and an inverter (43). The steering control device (20) includes a load torque sensor (39) that is attached between the electric motor device (34) and a load portion of a steering mechanism unit (21) to detect a load torque applied on a steering system, a steering load torque calculating section (41) that calculates a steering load torque based upon an output value of the load torque sensor (39), and an assistance torque calculating section (42) that adds the steering load torque outputted from the steering load torque calculating section (41) and a target steering torque input from an exterior to calculate an assistance torque to command the electric motor device (34) and command the inverter (43). |
US10207733B2 |
Rotational angle detection apparatus and power steering apparatus
The present invention provides a rotational angle detection apparatus and a power steering apparatus capable of preventing or reducing distortion of a detection member and improving detection accuracy. A welded plate and a yoke holder are fixedly welded to each other with a pair of yokes sandwiched between the welded plate and the yoke holder. |
US10207732B2 |
Steering column switch for a motor vehicle
A steering column switch for a vehicle includes a switching lever that operates by pivoting in relation to a housing. The lever has a locking pin which assumes a stable position on a switching gate when the lever is not operated and is guided into an unstable position by operation of the lever. The switching gate guides the pin back into the stable position when operation of the lever ceases. A permanent magnet on a body of the lever is brought against an electromagnet on the housing by pivoting the lever into the unstable position. The lever is held in the unstable position by magnetic attraction between the magnets for a time in which a function associated with the lever being actuated into the unstable position is active. Afterwards, the electromagnet produces a counter magnetic field which interrupts the magnetic attraction so that the lever returns to the stable position. |
US10207729B2 |
Folding type collapsible wagon
A folding type collapsible wagon comprises a frame assembly, a tow bar assembly and wheels, wherein the tow bar assembly is arranged in front of the frame assembly, and each side frame comprises coplanar X-shaped cross tube assemblies. Each coplanar X-shaped cross tube assembly comprises a first oblique tube, two second oblique tubes and a hollow seat, wherein a first strip opening is formed in the middle of the hollow seat in the front-back direction, tube connectors are oppositely arranged at the front end and the rear end of the hollow seat in the vertical direction respectively, the first oblique tube penetrates through the first strip opening and is hinged to the middle of the first strip opening at the center through a hinge shaft, the two second oblique tubes are mounted in the tube connectors at the front end and the rear end of the hollow seat respectively, the two second oblique tubes are arranged in parallel and intersect with the first oblique tube in an X shape, and the first oblique tube, the two second oblique tubes and the hollow seat are all located on the same plane. The folding type collapsible wagon provided by the present disclosure is high in space utilization rate and attractive. |
US10207725B2 |
Method and device for transmitting signal among compartments of train
A method and a device for transmitting signals among compartments of a train are provided. The method comprises: receiving a first signal transmitted via a jumper cable, and extracting first data carried in the first signal; receiving a second signal transmitted wirelessly corresponding to the first signal, and extracting second data carried in the second signal; and determining whether the first data is identical with the second data, and outputting the first signal in a case that it is determined that the first data is identical with the second data, or outputting the second signal in a case that it is determined that the first data is not identical with the second data. The method and the device improve the reliability of transmission of signals among compartments of a train. |
US10207719B2 |
Use of multiple internal sensors for measurements validation
A microcontroller-based method and apparatus are described for measuring motions signals (301) with a plurality of inertial sensors (302-304) contained within a device package housing and validating (420) a first measured motion signal (e.g., ΩX) by generating at least a first estimated value ΩX for the first motion signal (e.g., 419) based on at least a second measured motion signal (e.g., AY) and for comparing the first estimated value for the first motion signal (419) to the first measured motion signal ΩX in order to validate the first measured motion signal ΩX. |
US10207713B1 |
Electronic traction control
In general, the subject matter described in this specification can be embodied in methods, systems, and program products for performing vehicle traction control. Time intervals between points of rotation of a rotating vehicle output shaft are measured. Indicators of shaft rotation rate are generated using, for each generated indicator, a set of one or more of the time intervals. The generated indicators of shaft rotation rate are used to determine a value indicative of a rate of change of shaft rotation rate. An indicator of a maximum allowable output shaft rotation rate is computed. A current indicator of output shaft rotation rate is determined to exceed the maximum allowable output shaft rotation rate. In response to determining that the current indicator exceeds the maximum allowable output shaft rotation rate, a signal to trigger application of a traction control mechanism is output. |
US10207710B1 |
Steering and braking systems for a coasting motor vehicle
Apparatus for providing hydraulic line pressure and vacuum pressure to the braking and steering subsystems of a wheeled motor vehicle comprises one or more battery powered electric motors which drive one or more of a hydraulic pump and a vacuum pump. When the engine is stopped while the vehicle is moving, to save fuel, the electric motor(s) drive the pumps, so that hydraulic pressure and vacuum are provided, for safe operation of the vehicle. |
US10207701B2 |
Method for controlling a driveline in order to optimize fuel consumption
A method is provided to start a hybrid powertrain to optimize fuel consumption, wherein such hybrid powertrain comprises a combustion engine; a gearbox with input shaft and output shaft; a first planetary gear, connected to the input shaft and a first main shaft; a second planetary gear, connected to the first planetary gear and a second main shaft; first and second electrical machines respectively, connected to the first and second planetary gears; one gear pair connected with the first main shaft; and one gear pair connected with the second main shaft. The method comprising: ensuring that the moveable parts of each of the first and second planetary gears are respectively disconnected from each other; bringing the combustion engine to a predetermined engine speed (nice); and controlling the first and the second electrical machine in such a way that a desired torque (TDrv) is achieved in the output shaft. |
US10207700B2 |
Hybrid type work vehicle
A hybrid type work vehicle includes a power source, a traveling unit, a hydraulic work unit, an accelerator pedal, a brake pedal, an operation lever device, and a control apparatus. The control apparatus is configured such that when the current operation state is determined to be that of an excavation work which is a combined operation of the traveling unit and the hydraulic work unit and the output power limitation signal is outputted, the control apparatus limits the output power of the traveling unit. The control apparatus is also configured to decrease the tilting angle of the hydraulic pump, such that a ratio between the output power of the traveling unit and the output power of the hydraulic work unit is maintained at a preset ratio. |
US10207696B2 |
Timing transmission gearing shifts for a hybrid electric powertrain
A transmission shift is timed for a hybrid electric powertrain as a function of a torque capacity of an electric machine relative to a shifting torque required to change gearings of a transmission. A vehicle is being propelled by the machine, with an engine stopped, when the shift is requested. If the machine has insufficient torque capacity to change transmission gearings, then the shift request is delayed until the engine has started. |
US10207693B2 |
Brake system control unit for a vehicle
The brake system control unit for a vehicle having a hydraulic vehicle brake and an electromechanical brake device including at least one electric brake motor includes a microcontroller configured to actuate at least one active brake component of the vehicle. The control unit further includes a system ASIC configured to acquire sensor signals in the vehicle. The control unit further includes a brake motor ASIC configured to actuate an electric brake motor of an electromechanical brake device and acquire pedal travel transducer signals of the brake pedal of the vehicle. The control unit includes a plurality of communication interfaces to connect the microcontroller to the system ASIC and to the brake motor ASIC. |
US10207691B2 |
Brake apparatus
A brake apparatus includes a brake operation member, a state detection unit, a cylinder, a first portion, an operation rod, a stepped piston, first, second, and third seal members, first and second pressure chambers, a hydraulic source, and first and second oil passages. The brake apparatus also includes a fluid amount control unit. The fluid amount control unit is configured to control an amount of the brake fluid to be supplied to the first pressure chamber and the second pressure chamber. The fluid amount control unit is also configured to increase the amount of the brake fluid to be supplied to the second pressure chamber when the detected state is equal to a preset pressure increase request. |
US10207690B2 |
Brake apparatus
An object of the present invention is to provide a brake apparatus that allows low-cost attachment of a stroke sensor that detects a stroke amount of a brake pedal. The brake apparatus is configured in such a manner that the stroke sensor that detects an amount of an axial stroke of a piston is disposed between one side surface of a master cylinder housing and one side surface of a valve housing, and an output of the stroke sensor is transmitted via a through-hole formed on the valve housing when being transmitted to a control unit attached to an opposite side surface-side of the valve housing. |
US10207686B2 |
Vehicle wash component for emitting bubbles
A device for emitting bubbles in a vehicle wash facility includes a plenum supported with respect to the ground. The plenum includes an air inlet with a first area and an air outlet with a second area. The plenum air outlet is in communication with at least one foaming chamber. The foaming chamber includes a generally planar media element disposed therein. The foaming chamber includes a spray jet located therein, which is in communication with a source of chemical. The spray jet configured to emit a chemical onto the generally planar media element. The device also includes a plurality of nozzle portions in communication with the foaming chamber for emitting bubbles therefrom. |
US10207679B2 |
Fastening device for a windscreen wiper device
A fastening device (100, 200) configured to fasten a windscreen wiper device on a fastening element (50) of a vehicle, in particular of a motor vehicle. The fastening device (100) comprises: a first receiving region (110), into which the fastening element (50) can be introduced; and a securing element (120) mounted rotatably about a first axis of rotation (122), wherein the first axis of rotation (122) extends substantially perpendicular to a longitudinal extent (51) of the fastening element (50), and wherein the securing element (120) is configured to form an engagement with the fastening element (50) through a first rotation (124) about the first axis of rotation (122). |
US10207678B2 |
Vehicle access system
The invention relates to an access unit for communicating with a further access unit to control access to a vehicle. The access unit comprises at least a first transmitter for transmitting a polling signal; and at least a first receiver for receiving an authentication signal from the further access unit in response to the polling signal. At least the first transmitter is a first ultra-wideband transmitter and at least the first receiver is a first ultra-wideband receiver. The invention also relates to a vehicle access system which is a combination of the access and further access units. The invention also relates to methods of operating a vehicle access system and a vehicle access unit. |
US10207675B2 |
Vehicle keyless system and on-vehicle device of vehicle keyless system
At acquisition of a first unit command signal RC(1) of which storage is completed and in a case that the ring buffer stores a part of a second unit command signal RC(2), the CPU acquires the first unit command signal and the part of the second unit command signal upon receiving a first interrupt signal BQ(1), and then separates the first unit command signal and the part of the second unit command signal from each other. When having received a second interrupt signal BQ(2), the CPU acquires the remaining of the second unit command signal, and combines the remaining of the second unit command signal and the part of the second unit command signal. Accordingly, the second unit command signal once separated is acquired as a signal having all data completed. |
US10207671B2 |
Hybrid inflator with foam as a fuel
An inflator (10) is actuatable to provide inflation fluid for inflating an inflatable vehicle occupant protection device. The inflator (10) includes a volume of stored gas and a propellant (52) that is ignitable to undergo a reaction that produces reaction products. The reaction products include heat and gas that mix with the stored gas to produce a mixture of inflation fluid. The inflator (10) is configured to discharge the inflation fluid to inflate the protection device. The propellant (52) comprises an open cell foam fuel propellant (140). The reaction includes a combustion reaction in which the foam fuel propellant (140) reacts with a gas oxidizer comprising oxygen to produce heat and gas reaction products that mix with the stored gas. |
US10207668B2 |
Side airbag device
A side airbag device includes a folded-up airbag and a limitation member disposed around the airbag for constraining the airbag from protruding forward at airbag deployment. The limitation member is formed of a flexible sheet member into a band shape, and is joined to the folded-up airbag by the opposite end regions. The limitation member includes a loose region which is arranged around the folded-up airbag in such a manner as to be remote from the folded-up airbag. The loose region is disposed on a side of the folded-up airbag towards which the airbag protrudes. The loose region includes a tearable region in the region in a deployment direction of the airbag. |
US10207666B2 |
Bumper for a vehicle
A bumper for a vehicle includes a bumper crossbeam and two crash boxes extending away from a back of the bumper crossbeam. A one-piece blank made of fiber-reinforced sheet material extends from a wall section of the bumper crossbeam connecting the crash boxes, right into the crash boxes. |
US10207665B2 |
Bumper design using shear thickening fluids
A variable shear control energy absorption system for a vehicle is provided. The system may include a vehicle frame component and a primary deformable impact absorber located adjacent the vehicle frame component. The vehicle frame component may be a bumper reinforcement member. The system may include a plurality of secondary deformable impact chambers located within the primary deformable impact absorber, each secondary deformable impact chamber including a shear thickening fluid that exhibits an increasing or decreasing viscosity responsive to an impact force. At least one elastic relief chamber is provided in fluid communication with the plurality of secondary deformable impact chambers. The elastic relief chamber is configured to temporarily accept the shear thickening fluid from the plurality of secondary deformable impact chambers during low force impacts, and to redirect the shear thickening fluid back to the secondary deformable impact chambers after the low impact force recedes. |
US10207655B2 |
Layered composite component
A laminated composite part, which includes a first member having a predetermined mating surface, and a second member that is made of an elastically deformable resin material, that has a plate portion substantially parallel to the mating surface and having a multiplicity of protrusions formed integrally therewith so as to protrude toward the mating surface so that space is created between the plate portion and the mating surface, and that is placed on the first member such that the protrusions contact the mating surface, which has cushioning properties as tip ends of the protrusions are pressed against the mating surface and elastically deformed, and in which one of the first and second members which is located on a design surface side has an engaging projection that projects to a larger extent than the protrusions, and the engaging projection is inserted through an insertion hole formed in the other of the first and second members and is retained in the insertion hole, whereby the first and second members are connected together, the insertion hole being provided with a stopper portion that is engaged with the engaging projection to retain the engaging projection in the insertion hole, in order to allow the engaging projection to move relative to the stopper portion in a direction parallel to the design surface due to a difference in thermal expansion between the first and second members, the stopper portion having a predetermined length in a direction of the relative movement that occurs due to the difference in thermal expansion, the stopper portion being a bridge extending across the insertion hole and having a slit in a middle so as to be separated into a plurality of parts, and the engaging projection having an annular shape and being inserted through the insertion hole such that the engaging projection elastically deforms the bridge and expands the slit, and the bridge thus extending through an opening of the annular shape, so that the engaging projection is retained in the insertion hole by the bridge and is allowed to move relatively in a longitudinal direction of the bridge. |
US10207654B2 |
Retention system, in particular for a camera in an inside compartment of a vehicle
A retention system on a mounting structure for a generally cylindrical component extending in a transversal axis. The retention system includes a generally U-shaped spring clip comprising a base and a pair of resilient retainer arms extending from the base along a longitudinal axis and defining an inlet passage; and a member holding said U-shaped spring clip; the retainer arms are adapted to engage with an upper side of the component in front of the inlet passage. The member includes one or multiple rigid retention walls extending inside the spring clip and which are adapted to engage with a lower side of the component at distance of the base, in working position. |
US10207652B2 |
Parallelogram linkage automatic clamping holder
A parallelogram linkage automatic clamping holder includes a rear base, a bottom support arm, a left clamping arm, a right clamping arm, and a return elastic member. When in use, the bottom support arm is moved downward by the weight of a mobile phone. By the deformation principle of the parallelogram, clamping parts move inward obliquely upward to clamp the mobile phone automatically. The clamping surfaces of the clamping parts don't have an angle change to ensure that the mobile phone has a larger contact surface with the clamping surfaces, providing a better clamping effect. |
US10207651B2 |
Stable mounting system for seatback shelving
This invention relates to a mechanism for attaching shelving, hooks, and organizers to a vehicle seatback. The attachment mechanism fits over the vehicle seat headrest posts, providing stability to the shelving, hooks, or organizers. The mechanism is formed as a single piece, thus it can be installed and removed without any additional components such as screws, bolts, straps, or other parts. |
US10207650B1 |
Adjustable utility rack for trucks
The adjustable utility rack for trucks is a structure that removably attaches to a vehicle commonly referred to as a pickup truck. The adjustable utility rack for trucks creates a raised horizontal platform that is configured for use in carrying cargo. The dimensions of the adjustable utility rack for trucks are adjustable in the lateral, sagittal, and vertical directions such that the adjustable utility rack for trucks can be adjusted for both the dimensions of the pickup truck and the dimensions of the cargo. The adjustable utility rack for trucks comprises a plurality of sagittal rails, a plurality of lateral rails and a pedestal structure. The plurality of sagittal rails and the plurality of lateral rails support the transported cargo. The pedestal structure attaches the plurality of sagittal rails and the plurality of lateral rails to the pickup truck. |
US10207649B2 |
Multi-axis roof-rack mounting system
A multi-axis roof-rack mounting system includes a bracket member and a support member coupled to the bracket member. The bracket member includes a middle portion and two arm members connected to and extending upwardly from opposing lateral edges of the middle portion. The support member includes a curved portion having an elongate opening configured to allow lateral movement of a fastener passing through the support member, one or more saddle members moveably engaged with the support member, and a clasp member. The clasp member is coupled to the fastener and configured to be receivable within a rail. The bracket member is securable to a roof of a vehicle. |
US10207647B2 |
Full display mirror with gear-driven toggle mechanism
A rearview mirror for a vehicle includes a housing defining an interior cavity and an open side, a substrate coupled within the open side of the housing and having a reflective surface thereon, and an actuation mechanism coupled within the housing. The actuation mechanism includes a mounting plate rotatably coupled within the cavity of the housing at a first end thereof and a spring plate coupled with the mounting plate and having a resiliently deformable arm portion extending away from the mounting plate. The actuation mechanism also includes a socket body rotatably coupled within the interior cavity of the housing, the arm portion of the spring plate being operably coupled with the socket body along a coupling axis and a motor rigidly coupled within the interior cavity of the housing and operably coupled with the socket body to drive rotation thereof. |
US10207646B2 |
Vehicle front camera module integrated with rearview mirror
A vehicle front camera module integrated with a rearview mirror includes a windshield bracket module fixed to a central upper end of a windshield of a vehicle, a camera module fixed to the windshield bracket module and at which a pair of lenses for taking forward images of the vehicle are disposed to be laterally spaced apart from each other, and a rearview mirror coupled to the windshield bracket module through a supporter which is coupled to the windshield bracket module in front of the pair of lenses and extending downward so as not to interfere with respective angles of view of the pair of lenses. This arrangement enables the camera module to have a compact design with improved visibility for a safe driving experience. |
US10207643B2 |
Camera based trailer detection and tracking
A trailer detection system is configured to determine a presence of a trailer towed by a host-vehicle. The system includes a camera and a controller. The camera is used to capture an image of an area behind a host vehicle. The controller is in communication with the camera. The controller is used to detect a position of an edge in the image and determine that the edge is associated with a trailer towed by the host vehicle when the position of the edge moves less than a movement threshold. |
US10207642B2 |
Electrical power monitoring system
An electrical power monitoring system includes a base at an external surface of a wall of a junction box and including a stem configured to project through an opening in the wall, the base further including a monitoring circuit, a plurality of conductors extending through the stem and coupling the monitoring circuit to a plurality of conductive terminals in the junction box, and a fastener configured to mate with the stem of the base at an internal surface of the wall to fix the base to the wall, wherein the monitoring circuit is configured to monitor presence of electrical power at the plurality of conductive terminals, the monitoring circuit including a plurality of light sources at the external surface of the base. |
US10207635B1 |
System and method for automatically modifying brake light intensity
Systems and methods for detecting distracted drivers and reducing risks posed by the distracted drivers are disclosed. According to certain aspects, an electronic device may capture and analyze image data that depicts an operator of a vehicle in various levels of distraction. The electronic device may determine, based on the analysis, whether the operator is distracted, and determine an additional vehicle that may be located in front of the vehicle. The electronic device may generate and transmit a command to an additional electronic device that, upon execution, causes brake lights of the additional vehicle to modify in intensity. |
US10207634B2 |
Automatic control of a direction of travel indicator of a vehicle
A method for automatically controlling a direction of travel indicator of a vehicle having the following steps: receiving a signal for the chronologically limited activation of the direction of travel indicator, chronologically limited activation of the direction of travel indicator after reception of the signal for the chronologically limited activation of the direction of travel indicator, starting a timer for a measurement interval after reception of the signal for the chronologically limited activation of the direction of travel indicator, checking a steering angle measurement signal during the measurement interval, and deactivation of the direction of travel indicator as a function of the checking of the steering angle measurement signal. |
US10207633B2 |
Door handle
A door handle includes a casing inside which an accommodation space is provided, and a lamp unit disposed in the accommodation space. The lamp unit includes a light member, and a light guide that guides light emitted from the light member in a first predetermined direction and emits the guided light from a light output surface. In the door handle, the light output surface is positioned inside an outer surface of the casing. |
US10207630B2 |
Method for controlling a light scanner in a headlamp for vehicles
The invention relates to a method for controlling a light scanner (7) in a headlight for vehicles, wherein the laser beam of at least one modulated laser light source (1) is directed in a scanning manner, by way of the light scanner, onto a light conversion means (8) so as to generate a light image (11) thereon, which is projected via an imaging system (12) as a light image (11′) onto the roadway, a micromirror (10) of the light scanner is pivoted according to defined characteristic control curves in at least one coordinate direction, the desired light image (11) is divided into a pixel set having n rows and/or m columns, the horizontal and/or vertical characteristic control curves for the micromirror (10) are adapted to at least one selected row and/or column in terms of the required optical power of the pixels, and the adapted horizontal and/or vertical characteristic control curves are used to control the micromirror. |
US10207624B2 |
Pipe deployment trailer
A trailer is provided having a trailer base and a trailer bed mounted to the trailer base. The trailer includes at least one actuator coupled to the trailer bed and the trailer base that raises and lowers the trailer bed. When the at least one actuator is extended, the trailer bed is raised to a vertical orientation. When the at least one actuator is retracted, the trailer bed is in the horizontal orientation. The trailer includes a lifting head protruding outwardly from the trailer bed. The position of the lifting head is adjustable along a longitudinal axis of the trailer bed. |
US10207622B2 |
Vehicle loading device and method
A loading apparatus includes a first roller, a second roller, a first arm support, a second arm support, a support bar, a first clamp and a second clamp. The loading apparatus is useful for providing a loading apparatus to facilitate loading an article into and out of a vehicle. |
US10207619B2 |
SMA valve for controlling pressurized air supply to an air cell in a vehicle seat
The present invention provides a SMA valve for controlling pressurized air supply to an air cell in a vehicle seat comprising: a valve housing, a valve element (4) which is moveably suspended in the housing to be moveable between a closed position and an open position, a spring element adapted to exert a bias force on the valve element urging it to the closed position, and a SMA wire (1) extending between a part fixed in the housing and the valve element and arranged such that shortening of the SMA wire upon exceeding its threshold temperature exerts a force on the valve element which pulls the valve element away from the closed position against the bias force of the spring element, characterized in that the valve element (4) is suspended by a connecting link (10, 10′) connected with one of its ends to the valve element (4) and with its opposite end to a stationary component (8) in the housing by a hinge (12, 12′) enabling pivotal movement of the connecting link (10, 10′) between a first and second position of the connecting link corresponding to the closed and open position of the valve element (4), respectively. |
US10207617B1 |
Reduced-impact-and-recoil headrest
A reduced-impact-and-recoil headrest that includes a ratchet mechanism, allowing components to incrementally translate with respect to each other. The reduced-impact-and-recoil headrest includes an exterior housing surface that is deformable, providing cushioning for a vehicle occupant's head. The headrest also includes an interior compartment within the housing, with the ratchet mechanism disposed within the interior compartment. The headrest is configured to decrease the force of a collision experienced by the occupant, thereby decreasing the likelihood and severity of traumatic brain injuries resulting from the occupant's head striking a stationary headrest. Instead, the reduced-impact-and-recoil headrest is configured to incrementally move with the occupant's head, providing an incremental cushion for the occupant's head. The ratchet mechanism also prevents the reduced-impact-and-recoil headrest from automatically translating back to its pre-impact position, thereby decreasing the occupant's risk of ligament tear and whiplash. |
US10207615B2 |
Headrest
A headrest includes a stay having left and right legs; a headrest main body attached to the stay and able to rotate in a front-rear direction; a pair of elongated holes made in a bottom surface of the headrest main body and a pair of closing members arranged on the bottom surface of the headrest main body, covering the elongated holes, wherein each closing member includes a main plate and a sub-plate, the main plate has an insertion hole guiding one leg of the stay and moves in the front-rear direction as the main plate is rotated, and the sub-plate is provided, overlapping the main plate, and is able to move as the main plate moves; the main plate and the sub-plate may move as the headrest main body is rotated, while covering the elongated hole made in the bottom surface of the headrest main body. |
US10207612B2 |
Locking structure for armrest
A locking structure for an armrest is provided to be pivotable to a folded up or a pulled down position. The locking structure includes a locking pin disposed at a fixed position and a catch pivotably coupled to a fixing bracket in an armrest housing, and has an engaging portion formed at a side thereof so that the locking pin enters the engaging portion, and a projection and a recess are formed to be spaced apart from the engaging portion. A latch is coupled to the fixing bracket and has a protruding portion formed at one side of the latch. A knob rotates the latch and when the armrest housing rotates upward, the catch rotates while the locking pin enters the engaging portion to lock rotation of the armrest housing. When the latch is, the locking pin is withdrawn from the catch, to permit the rotation of the armrest housing. |
US10207609B2 |
Vehicle seat back with feature for grasping of seatbelt
A seat assembly for a vehicle includes a seat back having a cushion surface forming a bolster along a lateral edge thereof, a recess formed in the bolster, and a retractable seatbelt. When in a stowed condition, the seatbelt extends along the bolster between a top and a bottom thereof, and a portion of the seatbelt passes over the recess to create a space between an edge of the seatbelt and the cushion surface. The recess is sized and located to enable a seat occupant to insert fingers into the space and easily grasp the seatbelt for deploying it. The recess may be a depression in the cushion surface, or may be formed by a first portion of the bolster having a first radius smaller than a second radius of a second, un-recessed portion of the bolster adjoining the first portion. |
US10207607B2 |
Vehicle seat
A vehicle seat that ensures improving appearance. A vehicle seat includes a first cover member to which a terminal of a first skin is stitched and a second cover member to which a terminal of a second skin is stitched. The first cover member and the second cover member are joined together. This ensures reducing a displacement of the first skin and the second skin relative to the first cover member and the second cover member. This ensures reducing the first skin and the second skin being turned up at an outer edge of a flange portion of the first cover member and an end portion of the second cover member on the second skin side. This ensures improving appearance of the vehicle seat. |
US10207606B2 |
Recyclable plastic structural articles and method of manufacture
An in-situ molded foam core structural plastic article having an outer shell with an interior cavity filled with expandable polymer beads which when expanded substantially fill the interior cavity forming a thermal bond with the shell. The bead and shell are of a similar plastic composition enabling the articles to be reground and recycled. Various articles are disclosed including structural panels, and automotive seat, load floor, interior panel, bumper and running board components. An apparatus for forming the articles and an associated method of manufacture are also disclosed. |
US10207604B2 |
Seat assembly having a pivot mechanism
A seat assembly having a pivot mechanism that pivotally couples first and second portions of a seat back. The pivot mechanism may have a linkage tube and a linkage pin. The linkage pin may extend through the linkage tube and may have an enlarged head that may retain the linkage pin in the linkage tube. |
US10207603B2 |
Drive system for a tilt adjustment, vehicle seat, method for operating a drive system
A drive system (2) tilt adjusts a back rest (10) of a vehicle seat (1). The back rest (10) is held on a seat base (11) by a fitting (12). An output pinion (24), drivable by a drive motor (20), is provided on the seat back side and interacts with a tooth segment (18) arranged rotationally fixed on the base (11). A pivot movement of the back rest (10) can be carried out by the drive motor (20) while the fitting (12) is unlocked. The output pinion (24) can be uncoupled from the drive motor (20) by a coupling (22). A compensation spring (14) acting between the back rest (10) and the base (11) pre-tensions the back rest (10) in the direction of the non-use position. A vehicle seat (1) with the drive system and a method for operating a drive system (2) are also provided. |
US10207601B2 |
Vehicle seat
A vehicle seat includes: a seat cushion; a base provided on a vehicle body; a seat lifter configured to adjust a height of the seat cushion by a rotational motion of a link connecting the seat cushion to the base; and a fixture of a seat belt, the fixture being attached to the link. |
US10207595B2 |
Autonomous transport vehicle charging system
A charging system for autonomous transport vehicles including at least one charging contact disposed on each pick floor level of a storage and retrieval system, each of the at least one charging contact being located at a transfer station, at least one power supply configured to supply power to the at least one charging contact, and a controller in communication with the transfer station and being configured to communicate information relating to a transfer of items between the transfer station and a predetermined one of the autonomous transport vehicles and to apply power from the power supply to the at least one charging contact for charging the predetermined autonomous transport vehicle corresponding to the transfer and located at the transfer station, wherein the controller is configured to supply power to the charging contacts simultaneously with the predetermined autonomous transport vehicle exchanging items related to the transfer at the transfer station. |
US10207593B2 |
Means and methods for making an associative connection
A method is provided in which a pair of transmitters having omnidirectional and directional transmission characteristics is provided when an associative connection is established between an electric vehicle and a charging station. Once the associative connection has been established in such a way that a directional radio link is formed, the associative connection is tested using an omnidirectional transmitter. The results of the testing may be used to prevent an unwanted associative connection to a compromising transmitter. |
US10207591B2 |
Mobile vehicle charging system
The mobile vehicle charging system is applied to a mobile vehicle and includes a docking platform and a charging device. The docking platform provides parking to the mobile vehicle. The charging device includes an electricity transmission interface and an electricity measurement module. When the mobile vehicle is parked on the docking platform, the electricity transmission interface charges a battery module through an electricity reception interface of the mobile vehicle. As such, when an operator of the mobile vehicle parks the mobile vehicle onto the docking platform, the mobile vehicle can be automatically charged by the mobile vehicle charging system. |
US10207589B2 |
Electric cable and winding device for such a cable
The invention relates to a winding device (8) for an electric cable (4, 4a, 4b) including a cylindrical hub (62), perforated (622) at its surface and open (624) at at least one of its ends, the cable having at least one conductor (41, 42, 43, 44) and a sheath (45, 45a, 45b) with an outer surface having an irregular cross-section. |
US10207579B2 |
Fuel-mixing prevention filler neck device
A fuel-mixing prevention filler neck device is provided. The fuel-mixing prevention filler neck device includes a fuel dispensing gun insertion unit that receives a fuel dispensing thereinto and a coupling unit that provides fluid communication with a bottom of the fuel dispensing gun insertion unit. The coupling unit is disposed on an exterior circumferential surface thereof with coupling protrusions for fastening with a plurality of slots formed in a filler pipe. Further, a first side of a lower portion of the coupling unit is open to form a coupling region. A misfueling prevention unit slidably moves to the coupling region to be coupled to the coupling unit. Additionally, the misfueling prevention unit is closed when a gasoline fuel dispensing gun is inserted and being opened when a diesel fuel dispensing gun is inserted. |
US10207576B2 |
In-wheel motor drive device
An in-wheel motor drive device includes an electric motor to drive a wheel, a wheel support bearing assembly to support the wheel, and a speed reducer to reduce the rotation of the electric motor and then to transmit it to the wheel support bearing assembly, and a lubricant oil is supplied under pressure by an oil pump to the speed reducer to be lubricated. The use is made of a temperature detector to detect the temperature of the lubricant oil or the electric motor and an output limitter to limit the output of the electric motor in the event that the temperature detected by the temperature detector is not higher than a predetermined threshold value. |
US10207575B2 |
Efficient vehicle power systems
A power delivery system utilizing an array of electric generators connected to an array of electric drive motors, which in turn are connected to loads of varying power demand, the generators configured to turn on and off to match the loads of varying power demands. The electric generators may be connected to an array of engines, each engine configured to run at peak efficiency. As load demands change, the engines turn on and off to meet the load demands. The engines and electrical generators may also connect to a battery to maintain the battery charge in response to demands on the battery by the electric drive motor array. |
US10207574B2 |
Motor vehicle
A motor vehicle includes side sills that are disposed in pairs on the right and left sides of the motor vehicle and that has bag-shaped cross-sections when viewed from the front of the motor vehicle and a floor panel that constitutes bottoms of at least a passenger compartment and that is coupled to the side sills. The motor vehicle further includes a battery panel that is disposed below the floor panel so as to support batteries and that is coupled to the side sills and a battery movement allowance mechanism that allows movement of the batteries toward the inside of the side sills when the batteries are moved to one side in a vehicle-width direction and, consequently, a load from the batteries is applied to the side sills. |
US10207573B2 |
Battery mounting structure for vehicle
A battery mounting structure for maintaining a sufficient passenger compartment in vehicles is provided. The battery mounting structure comprises a pair of longitudinal side sills (11, 12), and a battery pack (7) disposed between the side sills (11, 12). A plurality of battery modules (9) are juxtaposed in a casing (8) of the battery pack (7). A linear depression (39) protrudes downwardly from a reinforcement member (15) situated underneath a floor panel (17) supported by the side sills (11, 12), and the battery pack (7) has a linear depression (38) hold the linear depression (39) therein. |
US10207566B2 |
Air conditioning system for vehicle including two condensers and a control door within a duct to selectively control airflow through said two condensers
An air conditioning system for a vehicle may include a cooling module including a cooling duct, a cooling-side inlet formed in a first end of the cooling duct, a cooling-side indoor outlet and a cooling-side outdoor outlet formed in a second end of the cooling duct, and an evaporator core provided in the cooling duct, a heating module including a heating duct, a heating-side inlet formed in a first end of the heating duct, a heating-side indoor outlet and a heating-side outdoor outlet formed in a second end of the heating duct, and a plurality of condensers provided in the heating duct, and a cooling blower and a heating blower respectively provided in the cooling duct and the heating duct, in which the plurality of condensers provided in the heating duct and the evaporator core provided in the cooling duct are coupled on a single refrigerant circuit. |
US10207565B2 |
Method and device for fastening a plastics component to a load-bearing component
The present disclosure relates to a method and device for fastening a plastics component to a load-bearing component. The fastening device includes a plastics component which is fastened to the load-bearing component by a screw connection, and a rubber-metal buffer which is arranged as a resilient support between the load-bearing component and the plastics component. The fastening device further comprises at least one metal tip which is arranged between the rubber-metal buffer and the plastics component, and which protrudes from a metal disk in the direction of the plastics component and engages at least partially in a surface of the plastics component when the plastics component is screwed to the load-bearing component. |
US10207562B2 |
Stabilizer support structure
A stabilizer support structure includes a suspension member in which a side rail portion and a cross-member portion are formed integrally, the suspension member including an upper suspension member that includes a first fastening portion at which a bracket is fastened at an intersection portion between the side rail portion and the cross-member portion, the bracket supporting a rod-shaped stabilizer whose length direction is in the vehicle width direction, and a lower suspension member that forms a closed cross section portion with the upper suspension member; and a reinforcing member that is joined to both the upper suspension member and the lower suspension member inside the closed cross section portion at the intersection portion, the reinforcing member spanning between the upper suspension member and the lower suspension member in the vehicle vertical direction, and being fastened together with the bracket via the first fastening portion. |
US10207557B2 |
Robotic working tool
A robotic work tool system may include a robotic work tool. The robotic work tool may include two front wheels and a chassis. The robotic work tool is characterized in that the two front wheels are arranged on a beam axle that is pivotably arranged to the chassis. |
US10207553B2 |
Amphibious vehicle
An improved amphibious vehicle comprising: a drive train; a plurality of ground engaging wheels; a cooling system; a water propulsion system; and a hull which defines a passenger compartment, wherein the form/shape of the hull below the waterline is substantially defined by a plurality of buoyancy modules that are demountably mountable to the amphibious vehicle. |
US10207550B2 |
Rotary joint assembly
A rotary joint assembly including a rotating portion. The rotating portion includes an annular body and a pair of annular sealing members. Each annular sealing member of the pair of annular sealing members is attached to a side of the annular body. An air passageway is formed in the annular body. The rotary joint assembly also includes a non-rotating portion. The non-rotating portion has a non-rotating portion air passageway formed therein. The non-rotating portion air passageway is in fluid communication with the air passageway formed in the annular body. A pair of annular air seal members are provided between the rotating portion and the non-rotating portion. Each annular air seal member of the pair of annular air seal members contacts a sealing surface of one of the annular seal members to provide a seal around an interface between the air passageway formed in the annular body and the non-rotating portion air passageway. |
US10207549B2 |
Bead wire for a tire, tire and manufacturing method
The bead wire (52) comprises several windings of wire and a basic hexagonal bead wire (56) comprising: two axially and radially external lateral rows (F1, F2) of N2 windings, two axially external and radially internal lateral rows (F3, F4) of N2 windings, where N1=N2+1 or N1=N2, two junctions (J1, J2), each formed by a winding that an axially and radially external lateral row (F1, F2) and an axially external and radially internal lateral row (F3, F4), have in common, each winding in common having no winding of wire axially on the outside of it. The bead wire (52) comprises two axially and radially external additional lateral rows (A1, A2) of N3 windings substantially parallel respectively to each axially and radially external lateral row (F1, F2). |
US10207547B2 |
Shield-shaped side-wall protection element and protective device for a vehicle tire
The invention relates to a shield-shaped side-wall protection element for a vehicle tire and to a protective device for vehicle tires. In order to provide a side-wall protection element for vehicle tires that can optimally protect a tire side wall under rough conditions, that can be produced economically, and is easy to install, the invention provides a shield-shaped side-wall protection element for a vehicle tire, comprising a radially inner base, an outer edge, which forms the radially outer end and which extends in a circumferential direction, and with a shield segment, which extends from the outer edge at least to the base, wherein the outer edge is at least partially offset axially inward from the base). The protective device for vehicle tires according to the invention comprises a plurality of shield-shaped side-wall protection elements arranged overlapping in the manner of shingles in a circumferential direction. |
US10207546B2 |
Pneumatic tire
Provided is a pneumatic tire including a tread that defines a groove formed between each pair of lands. The groove includes a curved inclined part and a bottom groove part that is located adjacent thereto in a groove width direction. The curved inclined part includes a concave inclined surface that is inclined from a surface of the lands toward a groove depth side. The bottom groove part is located adjacent to the curved inclined part via a stepped portion, and has a bottom surface located on a side deeper than a groove deep end edge of the curved inclined part. |
US10207542B2 |
Pneumatic radial tire for passenger vehicle
An object of the present invention is to adequately control relationship between a cross sectional width SW and an outer diameter OD of a pneumatic radial tire for a passenger vehicle. The tire is further characterized in that, provided that each half portion in the tire width direction of a ground contact surface of the tire is divided in the tire width direction into three equal portions including a tire-width-direction center portion, a tire-width-direction intermediate portion and a tire-width-direction outer portion from the tire-width-direction center side, rigidity in the tire circumferential direction of the belt reinforcing layer in a region in the tire width direction thereof corresponding to the tire-width-direction outer side portion is lower than rigidity in the tire circumferential direction of the belt reinforcing layer in a region in the tire width direction thereof corresponding to the tire-width-direction center portion. |
US10207540B2 |
Functionalized polymer blends for improved wear
A tire tread formed at least in part from a rubber composition that is based upon a cross-linkable rubber composition that may include between 50 phr and 90 phr of a first highly unsaturated elastomer being middle chain functionalized with an aminoalkoxysilane group and having a Tg of between −108° C. and −45° C. and between 10 phr and 50 phr of a second highly unsaturated elastomer being end-chain functionalized with a silanol group and having a Tg of between −108° C. and −10° C. The rubber composition may further include between 50 phr and 150 phr of a silica filler and a plasticizing system comprising between 5 phr and 120 phr of a plasticizing resin having a Tg of at least 25° C. and between 0 phr and 60 phr of a plasticizing liquid. |
US10207539B2 |
Vehicle spindle and a method of attaching the spindle to a portion of an axle housing
A vehicle spindle and a method of attaching the spindle to a portion of an axle half shaft housing. The spindle has an inner surface, an outer surface, one or more bearing journals on the outer surface of the spindle and a radially protruding portion circumferentially extending from at least a portion of the outer surface of an axially inboard end portion of the spindle. Prior to attaching the spindle to the axle half shaft housing, the one or more bearing journals are ground, a clocking angle for the radially protruding portion of the spindle is determined and the spindle is aligned to the determined clocking angle. Once the spindle is aligned to the determined clocking angle, the axially inboard end portion of the spindle is attached to an axially outboard end portion of the axle half shaft housing using one or more welds. |
US10207538B2 |
Device for simultaneously removing and tightening a plurality of lug nuts
The present invention provides an improved device for simultaneously replacing a plurality of lug nuts through the use of computer technology, modularity, energy-efficiency, safety features and ease of use. Computer technology monitors and controls the torque on each lug nut. This invention also displays the loosening or tightening status of each lug nut on a small LCD screen. The present invention achieves modularity through a series of interchangeable gear train assemblies, contained in separate unitary housings, which correspond to respective vehicular wheel depth and wheel lug patterns. Also, magnetic concentric sockets are used to capture and hold lug nuts as they are removed from the vehicle's wheel and to remove and replace theft protection devices such as rim or wheel locks. This invention provides ease of use with user-friendly controls and a light-weight unitary housing that eliminates the need of assistance from another person. |
US10207525B2 |
Image forming apparatus and image forming method
Provided are an image forming apparatus and an image forming method capable of coping with a medium exceeding a transport limit of a pair of rollers in image formation in which the medium is transported with the medium interposed between the pair of rollers. In a case where a medium exceeding a transport limit of first transport means to which medium transport using a first roller and a second roller is applied is used, second transport means is used to assist in the medium transport performed by the first transport means. The driving of second driving means for driving the second transport means is controlled using a driving signal applied to the driving control of the first driving means for driving the first transport means. Medium transport in which synchronization is taken between the first transport means and the second transport means is realized. |
US10207518B2 |
Method for compensating for failed printing nozzles in an inkjet printing machine by using deviating nozzles
A method for compensating for failed printing nozzles in an inkjet printing machine uses a computer to provide an increased ink drop volume of adjacent nozzles. All existing printing nozzles are measured regarding print failure and deviation of a printed dot beyond a specific threshold, so that the printing nozzles are marked either as functioning, failed, or printing a dot deviating in a direction transverse to the printing direction, and the results are saved on the computer. The computer hides all functioning printing nozzles and marks all remaining isolated printing nozzles as failed nozzles. The computer groups adjacent remaining printing nozzles by marking nozzles printing a dot deviating in a direction transverse to the printing direction as functioning printing nozzles contributing to the compensation or as failed printing nozzles in accordance with a rule, and the computer compensates for all printing nozzles having been marked as failed. |
US10207517B1 |
Image recording apparatus
An image recording apparatus is configured to record an image which includes multi-pass recording of completing a line image by performing a recording pass a plurality of number of times. The recording processing is configured to be executed in: a first recording mode in which the multi-pass recording of completing the line image is executed by performing the recording pass a first number of times, the recording pass being performed only when moving a carriage toward one side in a scanning direction; and a second recording mode in which the multi-pass recording of completing the line image is executed by performing the recording pass a second number of times larger than the first number of times, the recording pass being performed when moving the carriage toward the one side in the scanning direction and another side in the scanning direction. |
US10207516B2 |
Fluid ejection device
A fluid ejection device includes a fluid slot, a first fluid ejection chamber communicated with the fluid slot and including a first drop ejecting element, a second fluid ejection chamber including a second drop ejecting element, and a fluid circulation path including a first portion communicated with the fluid slot and the second fluid ejection chamber, and a second portion communicated with the first fluid ejection chamber and the second fluid ejection chamber, with the fluid circulation path including a fluid circulating element within the first portion. |
US10207513B2 |
Pressure controlling apparatus and liquid ejecting apparatus
A pressure controlling apparatus includes a seat having a communication hole through which a first space and a second space, in which a liquid flows, are in communication with each other, a pressure receiving plate configured to move with a change in pressure in the second space, a valve member configured to open and close the communication hole in conjunction with the movement of the pressure receiving plate, and a biasing member disposed between the pressure receiving plate and the seat and configured to bias the pressure receiving plate. The biasing member includes a first portion in contact with the pressure receiving plate and a second portion positioned closer than the first portion to the seat. The first portion has a larger diameter than the second portion. |
US10207511B2 |
Ink cartridge and ink jet printer
There is provided an ink cartridge capable of accomplishing satisfactory electrical connection relative to a printer main assembly. An ink cartridge detachably mountable to a cartridge mounting portion provided with an ink receiving tube and a plurality of electrical connecting portions, the ink cartridge including a tube inserting portion into which the receiving tube is insertable, a substrate provided on a front side in a position above the tube inserting portion, a plurality of electrical contacts electrically connectable with the plurality of electrical connecting portions, the electrical contacts being arranged on the substrate in a direction crossing with a direction from a bottom surface toward an upper surface. |
US10207506B2 |
Inkjet printing apparatus and recovery method of print head
There is provided an inkjet printing apparatus that can execute a recovery process appropriate for a print head according to a use condition of the inkjet printing apparatus. Therefore a recovery operation is performed based upon both an elapsed time in a non-use state where the printing is not performed and an elapsed time from the previous recovery process. |
US10207505B1 |
Method for fabricating a charging device
A method of fabricating a charging device for an inkjet printing system includes providing a charging device body having at least one conductive trace passing through the interior of the charging device body connecting between a charging face of the charging device body and an interconnection region remote from the charging face. A portion of the at least one conductive trace is exposed on the charging face. A vapor deposition process is used to deposit a conductive base layer through a shadow mask onto the charging face, wherein the deposited conductive base layer contacts the exposed portion of at least one conductive trace. One or more conductive metallic layers are plated onto the deposited conductive base layer to form a charging electrode. |
US10207503B2 |
MEMS device, liquid ejecting head, liquid ejecting apparatus, and MEMS device manufacturing method
A MEMS device includes a first substrate provided with a plurality of first electrode terminals and a second substrate composed of a crystalline substrate and provided with a plurality of second electrode terminals respectively corresponding to the first electrode terminals. The first electrode terminals and the second electrode terminals are electrically bonded one-to-one. Protrusions are formed at positions corresponding to the first electrode terminals on a mounting face of the second substrate opposing the first substrate. The second electrode terminals include the protrusions and conductive material covering the protrusions. |
US10207502B2 |
Liquid ejecting head, liquid ejecting apparatus, and piezoelectric element
A liquid ejecting head includes a piezoelectric element having a first electrode on a vibration plate, a piezoelectric layer on the first electrode, and a second electrode on the piezoelectric material layer. The piezoelectric layer has functional portions sandwiched between the first and second electrodes; the second electrode configures a common electrode provided continuously across a plurality of the functional portions; the piezoelectric layer extends to an outer side of an end of the first electrode; the vibration plate has a first region opposing the first electrode, a second region opposing an area of the piezoelectric layer extending further toward an outer side than the first electrode, and a third region further toward the outer side than the piezoelectric layer; the second region has a thickness substantially equal to or greater than the thickness of the first region; and the third region is thinner than the first region. |
US10207496B2 |
Liquid jetting apparatus and wiring member
A liquid jetting apparatus includes: a head unit including a first driving element, a second driving element, a first contact portion connected to the first driving element, and a second contact portion connected to the second driving element; and a wiring member including a flexible substrate, a first driving IC provided on the flexible substrate, a second driving IC provided on the flexible substrate, a first wire formed in the flexible substrate and connecting the first driving IC and the first contact portion, and a second wire formed in the flexible substrate and connecting the second driving IC and the second contact portion. A conductive part different from the first wire and the second wire is disposed in an area of the flexible substrate between the first driving IC and the second driving IC. |
US10207490B2 |
Ultrafine fiber printing system
An ultrafine fiber printing system contains a moving deck having a nozzle seat that is disposed on the moving deck. A pipe is installed in the nozzle seat, and a nozzle is disposed at the bottom end of the pipe. The upper portion and the lower portion of the pipe are combined with a heat dissipating unit and a heater respectively. The top end of the pipe is connected to a feed tube having an outer end connected with a thread squeezer. A printing platform is disposed around the moving deck. The nozzle is connected to a static electricity supply, and the fiber carrier is grounded. An electric field is formed between the nozzle and the fiber carrier. The droplets exported from the nozzle are stretched into ultrafine fibers to form a patterned fabric or product. |
US10207488B2 |
Three-dimensional object generating apparatus
A 3D object generating apparatus includes an optical-transparent, a laser light generating module, and a controller. The laser light generating module includes a light emitter for outputting a spot beam, a polygon mirror, a flat-field convergent lens, and a flat-field optical sensor. The polygon mirror directs the spot beam into a linear beam. The flat-field convergent lens is positioned between the laser light generating module and the optical-transparent component, and a flat-field scanning route is formed after the linear beam passed through the flat-field convergence lens. The flat-field optical sensor is positioned on the flat-field scanning route senses an optical power of the linear beam and generates a sensed signal. The controller is electrically connected to the laser light generating module and the flat-field optical sensor, and receives the sensed signal and calibrates the optical power of the spot beam based on the sensed signal. |
US10207486B2 |
Method of making vacuum insulated glass (VIG) window unit including activating getter
Methods of making vacuum insulated glass (VIG) window units are provided, including activating getters in a process of making VIG window units. In certain example embodiments, at least one getter is activated during and/or at the end of a pump-out/evacuation process in which the cavity between the substrates is evacuated. In certain example embodiments, the getter(s) may be activated (e.g., by at least a laser beam that is directed through a pump-out tube) during and/or at the end of the evacuation process in which the cavity between the substrates is evacuated to a low pressure that is below atmospheric pressure. |
US10207475B2 |
Mat-faced board
Disclosed is an improved facer mat for use as a cover sheet for gypsum board. Also disclosed are gypsum boards containing such mat facers on one or both major surfaces of the board (face and back sides when installed), a method of manufacturing such board, and a method of making the mat. The mat can comprise glass, thermoplastic, and/or thermoset fiber. In preferred embodiments, binder is included with the fiber. The mat has outer and inner surfaces. The mat comprises a first region adjacent to the outer surface defined along a horizontal plane of the mat, the first region having a first substantial thickness, and a second region adjacent to the inner surface defined along a horizontal plane of the mat, the second region having a second substantial thickness. The first region has (a) more hydrophilicity than the second region, (b) more wettability than the second region, and/or (c) less density than the second region. |
US10207471B2 |
Perforated ceramic matrix composite ply, ceramic matrix composite article, and method for forming ceramic matrix composite article
A ceramic matrix composite article, method for forming the article, and perforated ply which may be incorporated therein are disclosed. The article includes at least one shell ply forming an exterior wall having first and second portions and defining a plenum. An annular brace formed of at least one structural support ply is disposed within the plenum, including a first integral portion integral with and part of the first portion of the exterior wall, a first curved portion extending from the first integral portion and curving across the article plenum to the second portion of the exterior wall, a second integral portion integral with and part of the second portion of the exterior wall, a second curved portion extending from the second integral portion and curving across the article plenum to the first curved portion, and an overlap in which the first and second curved portions are integral. |
US10207470B2 |
Cylindrical base, master and master manufacturing method
Provided are a cylindrical base, a master and a method for manufacturing a master enabling a uniform transfer of a fine pattern. A cylindrical base of a quartz glass having an internal strain in terms of birefringence of less than 70 nm/cm is used. A resist layer is deposited to an outer circumference surface of this cylindrical base, a latent image is formed on the resist layer, the latent image formed on the resist layer is developed and the pattern of the developed resist layer is used as a mask for etching to form a structure including concaves or convexes arranged in a plurality of rows on the outer circumference surface of the cylindrical base. |
US10207467B2 |
Pultrusion methods and arrangements for manufacturing a fibre-reinforced composite product
In a pultrusion method for manufacturing a fiber-reinforced composite product comprising reinforcing fibers embedded in a thermoplastic matrix material, the following is performed along a path of pultrusion: providing a preform; further downstream, inductively heating the preform to a processing temperature of the thermoplastic matrix material; and, further downstream, introducing the preform into a die and consolidating the preform by means of the die while the preform passes through the die. |
US10207464B2 |
Method for defining fiber trajectories from curves or constraint grid
A method for defining trajectories of fibers on a layup surface for producing at least one ply having a given theoretical orientation, by laying up fibers, including the steps of providing the definition of the constraint curves and/or the definition of at least one constraint grid with association of at least one constraint vector to each node of the constraint grid, the direction of a fiber at an analysis point of the layup surface, being obtained by calculation of the normalized weights of the constraint vectors of the constraint curves and/or by calculation by of the normalized weights of the constraint vectors of the constraint grid, and by weighting by the normalized weights of the constraint vectors. |
US10207463B2 |
Method for producing a fiber composite component for aerospace
The invention relates to a method and a molding core for producing a fiber composite component (34), in particular in aerospace, comprising the following method steps: introducing a core sleeve (9) into a molding tool (2) for establishing an outer geometry of a molding core (27) to be formed; filling the core sleeve (9) that is introduced with a vacuum-fixable filling material (21); applying a vacuum to the core sleeve (9) and consequently vacuum-fixing the filling material (21) for forming the molding core (27); and at least partly laying at least one semifinished fiber product (33a, 33b) on the molding core (27) that is formed, for the shaping of the fiber composite component (34) to be produced. |
US10207462B1 |
Printer assembly
A material transport assembly for a printer assembly can include a toothed component; a drive for rotation of the toothed component; a material guide; and a biasing component that biases the material guide in a direction toward the toothed component. |
US10207460B2 |
Method of making hinged fasteners by three-dimensional printing
A fastener is provided. In another aspect, a fastener is made of layers of material, a light curable material and/or multiple built-up materials. Another aspect uses a three-dimensional printing machine to emit material from an ink jet printing head to build up a fastener. |
US10207459B2 |
Working method for end portion of plate member, manufacturing method for plate member, working apparatus for end portion of plate member, and plate member
A working method for an end portion of a plate member includes heating and pressing the end portion of the plate member formed of a thermoplastic resin in a thickness direction to form a thin portion, folding the thin portion such that a pressed surface is positioned inside to move an outer peripheral end of the thin portion as an end portion on an outer peripheral side of the plate member to the vicinity of a main body portion of the plate member to which an inner end of the thin portion as an end portion on an inner side of the plate member is connected, and pressing the outer peripheral end of the thin portion in the thickness direction to move the outer peripheral end thereof further inward than a surface of the main body portion in the thickness direction. |
US10207456B2 |
Clamping system for positioning a first component and a second component relative to each other as well as a method for producing a dimensional compensation between two components
A clamping system for positioning a first component and a second component relatively to each other includes a clamping device, a separating foil and an electrical contacting device. The clamping device is adapted to fix the first and second components in a desired joining position under creation of a gap therebetween with a characteristic measure of tolerance relative to each other in a first position of the clamping device and to release this fixation in a second position of the clamping device. The separating foil includes an anti-stick layer and a heating layer connected with electrically conducting contact zones for heating a compensation compound arranged in the gap. The electrical contacting device is mechanically couplable with the clamping device or a supporting device holding the clamping device and is adapted for creating an electrical contact with the contact zones at least in the first position of the clamping device. |
US10207455B2 |
Flexible pipe with corrosion resistant layer
The present techniques are directed to a flexible pipe. An inner carcass layer forms the innermost layer of the flexible pipe. An inner sheath layer and an outer sheath layer are disposed externally of the inner carcass layer. A layer of corrosion resistant alloy is disposed at any location between the inner carcass layer and the outer sheath layer. At least one armor layer is disposed internally of the outer sheath layer. |
US10207451B2 |
Thermoform packaging machine with movable mold insert
The present invention relates to a thermoform packaging machine with a forming station. The forming station can include a forming tool lower part with at least one mold insert that is movable relative to the forming tool lower part. The present invention also relates to a method of forming a film including the step of moving the mold insert, relative to the forming tool lower part and the formed film, to a removal position while the film is clamped between the forming tool upper part and the forming tool lower part. |
US10207450B2 |
Plastics connecting seam, plastics bottle with a connecting seam and method for the production thereof
The invention relates to a plastics connecting seam for the fluid-tight connection of at least two plastics surfaces. The plastics connecting seam is in the form of a plastics connecting seam that supports strength under a load in such a way that a load acting in a standard load direction increases the connection strength of the seam. |
US10207448B2 |
Method for changing a material and corresponding extrusion device
The invention relates to a method for the changing of material from a starting material to a subsequent material with an extrusion device (10) for the production of extrusion products (100) comprising the following steps: recognition of a change of material requirement, performance of at least one preparation step for the change of material, performance of the change of material after termination of at least one of the preparation steps. |
US10207440B2 |
Apparatus and method for formation of multi-region articles
An injection-molding apparatus for article formation. The injection-molding apparatus includes a single mold base supporting at least one grouping of a plurality of shape-forming configuration sets. Each set is shaped for forming one layer of a multilayered article comprising an asymmetric surface. Each set may include at least one cavity which retains each article region formed by the preceding injection-molding shot(s). The single mold base includes an internal movable part which moves within the single mold base with respect to a stationary part such that relative positions of the shape-forming configurations are advanced for each set to form a subsequent article region in the cavities. Each subsequent shot may be prior to full cooling of the article region formed in the previous shot. |
US10207436B2 |
Molded pocket in transaction card construction
Methods and apparatuses are provided for manufacturing a transaction card. The disclosed methods and apparatuses may be used to form a transaction card frame within a mold. The transaction card frame may include one or more recessed portions formed within a first surface of the transaction card frame. The one or more recessed portions may be configured for affixing one or more electronic components. |
US10207428B2 |
System for molding plastic materials
A material handling and mold filling system is provided which directs the flow of molten plastic material from an extruder and allocates the molten material to a plurality of nozzles through the use of independently operated, variable valves. The system therefore provides independent streams of molten plastic material having variable temperatures and flow rates or volumes to particular sections or regions of the mold. This independent temperature or flow of molten plastic material facilitates the complete, rapid and accurate filling of the molds, reducing turbulence and other temperature or flow-related imperfections in the finished components. A multiphase material handling system is also disclosed for expeditious sequential and simultaneous filling and pressing of the mold and extracting the completed component from the system. |
US10207424B2 |
Mixing elements having an improved dispersing effect
The invention relates to mixing elements that have a larger number of basic geometric periods per section and an improved dispersing effect for multi-shaft screw extruders comprising screw shafts that co-rotate in pairs. The invention further relates to the use of the mixing elements in multi-shaft screw extruders, a corresponding screw extruder comprising the mixing elements, and a method for extruding kneadable materials. |
US10207423B2 |
Extruder mixing element for a co-rotating twin screw extruder
A dispersive mixing element for co-rotating twin screw extruder is disclosed. The element for co-rotating twin screw extruder comprises of a continuous flight helically formed thereon having a lead ‘L’, wherein either the flight transforms at least once from an integer lobe flight into a non-integer lobe flight in a fraction of the lead ‘L’ and transforms back to an integer lobe flight in a fraction of the lead ‘L’ or the flight transforms at least once from a non-integer lobe flight into an integer lobe flight in a fraction of the lead ‘L’ and transforms back to a non-integer lobe flight in a fraction of the lead ‘L’. |
US10207421B1 |
Automated multi-headed saw and method for lumber
A system including a gantry structure; a first and a second saw head movable along at least part of the length of the gantry structure; and a first and a second lumber support also movable along corresponding lengths of the gantry structure. A controller moves the first saw head and first lumber support adjacent a first location along a board and moves the second saw head and second lumber support adjacent a second location along a board, and operates the first and second saw heads to cut first and second ends off the board. The controller then moves the saw heads and the lumber supports relative to the board to third and fourth locations and operates the first and second saw heads to cut third and fourth end pieces off. The saw heads and lumber supports optionally move together and rotate around respective vertical axes to enable angled board cuts. |
US10207420B2 |
Fabricating a plate of large thickness including a detachable card of small thickness
A method and tooling for fabricating a thin plastic plate of large format and of large thickness and including a card of small format and of small thickness that is detachable from the plate. The method, which may be implemented using the tooling, includes operations for making a spotface in a face of the plate to a depth equal to the difference between the large thickness and the small thickness; punching in the spotface zone along a leveling direction facing another face of the plate opposite from the first face, to a leveling stroke (en) equal to the depth of the spotface, in order to bring the bottom of the spotface level with the first face of the plate; and pre-cutting an outline of the card within the leveled zone, in order to make the card detachable. |
US10207417B2 |
Servo-driven cutting mechanism for driving a multi-directional cutting edge
A cutting assembly for cutting an extruded edible material includes an extrusion assembly having a food extrusion port that extrudes an edible material in an extrusion direction. A cutter frame having a cutting edge is positioned proximate the food extrusion port. The cutting edge moves through a cutting region proximate the extrusion port in a cutting motion. First and second servo motors are operably coupled to the cutter frame, wherein the first servo motor operates the cutting edge to define a first component of the cutting motion perpendicular to the extrusion direction. The second servo motor operates the cutting edge to define a second component of the cutting motion generally parallel with the extrusion direction. The first and second servo motors combine the first and second components to define a cutting path and a return path of the cutting edge through the cutting region. |
US10207412B2 |
Platform including an industrial robot
A platform including at least one industrial robot, wherein the platform is arranged to be carried by a vehicle to a working site where the at least one industrial robot is to perform a task in relation to the working site. The platform includes a platform body, a platform control unit and a connecting arrangement with a connecting device arranged to be connected to a vehicle arm of the vehicle such that the platform can be carried by the vehicle arm of the vehicle. The connecting arrangement further includes an actuator arranged to cause the platform to rotate around an axis X-X defined by the connecting device according to instructions from the platform control unit. A vehicle including the platform is also described. |
US10207410B1 |
Robotic autonomous navigation and orientation tracking system and methods
A system and apparatus for navigating and tracking a robotic platform includes a non-contact velocity sensor module set positioned on the robotic platform for measuring a velocity of the robotic platform relative to a target surface. The non-contact velocity sensor module set may include a coherent light source that is emitted towards the target surface and reflected back to the coherent light source. Measuring the change in intensity of the reflected coherent light source may be used to determine the velocity of the robotic platform based on the its relationship with the principles of a Doppler frequency shift. A communication unit may also be utilized to transmit data collected from the non-contact velocity sensor set to a computer for data processing. A computer is then provided on the robotic platform to process data collected from the non-contact velocity sensor set. A user may then monitor the determined trajectory path of the robotic platform and transmit navigation instructions to the robotic platform based on the received trajectory path data. |
US10207409B2 |
Image processing method, image processing device, and robot system
An image processing method can suppress detection accuracy of a detection target object from being lowered even if the detection target object has a different surface condition because of the influence of various kinds of noise. The image processing method includes the following operations of generating a captured model edge image by executing edge extraction processing on a captured model image acquired by capturing a detection target object, executing pattern matching of the captured model edge image and a model edge image, calculating similarity at respective edge points in the model edge image in the pattern matching of the captured model edge image and the model edge image, selecting an edge point to be eliminated based on the similarity from among the respective edge points in the model edge image, and generating an edge image acquired by eliminating the selected edge point as a final model edge image. |
US10207407B1 |
Robotic operation libraries
Example implementations relate to robotic operations libraries. An example library may include sets of operation instructions and other information for robotic devices to use to complete desired tasks. For instance, a respective set of operation instructions is determined based on successive simulations in which a virtual robotic device comprising an adjustable configuration initially based on the given configuration of a robotic device performs operations related to a task in an adjustable virtual environment until one or more simulations result in the virtual robotic device performing respective operations that complete the task at a success level that satisfies a predefined threshold. The library may provide a set of instructions for performing operations to a robotic device based on a query received from the robotic device that includes information indicative of a configuration and an environment of the robotic device. |
US10207402B2 |
Deep machine learning methods and apparatus for robotic grasping
Deep machine learning methods and apparatus related to manipulation of an object by an end effector of a robot. Some implementations relate to training a deep neural network to predict a measure that candidate motion data for an end effector of a robot will result in a successful grasp of one or more objects by the end effector. Some implementations are directed to utilization of the trained deep neural network to servo a grasping end effector of a robot to achieve a successful grasp of an object by the grasping end effector. For example, the trained deep neural network may be utilized in the iterative updating of motion control commands for one or more actuators of a robot that control the pose of a grasping end effector of the robot, and to determine when to generate grasping control commands to effectuate an attempted grasp by the grasping end effector. |
US10207398B2 |
Tool assembly
A tool assembly includes a first tool and a second tool. The first tool includes a first tool body, a ratchet mechanism defining a first hole, and a receiving space. The ratchet mechanism includes a ratchet having a plurality of teeth and a pair of pawls, and a first end of each of the pawls is received between two adjacent teeth. The second tool includes a first inner hexagonal wrench and a first outer hexagonal opener. The first outer hexagonal opener may be received in the first hole. When the first tool rotates relative to the ratchet mechanism along a first direction, the pawls rotates with the first tool and drives the ratchet together with the second tool rotates along the first direction; when the first tool rotates along a second direction opposite to the first direction, the ratchet together with the second tool is in a static state. |
US10207394B2 |
Locking pliers with improved adjustment member
A hand tool includes a first jaw, a first handle fixed to the first jaw, a second jaw, and a second handle pivotally coupled to the second jaw, a link member, and an adjustment member. The adjustment member is operable to axially move a first end of the link member to vary a distance between the first and second jaws. The adjustment member includes an engagement surface engageable with the first end of the link member, a shank in threaded engagement with a bore in the first handle, and a flange extending from the shank opposite the engagement portion. The flange includes a first side, a second side opposite the first side, and an elongate opening extending through the first and second sides. |
US10207391B2 |
Dry ice parts finishing system
Apparatus for treating parts to remove imperfections in the parts includes: a chamber; a rotatable basket within the chamber; a source of liquified cold fluid; a source of dry ice particles; a programmed controller to control rotation of the basket, activation of the liquified cold fluid, cycle times and activation of the dry ice particles. The controller is programmed to activate rotation of the rotatable basket, activate the source of liquified cold fluid and activate the dry ice particles to treat parts in the rotatable basket. |
US10207382B2 |
Grinding machine and method for machining a workpiece
The invention concerns a method for machining a workpiece (1) by a grinding machine, comprising the step of rotating and translating the workpiece along a first axis (4) toward the first abrasive wheel; rotating an abrasive wheel (6) around a second axis (61) and translating it along a third axis (62) such that the abrasive wheel grinds a peripheral portion (103) of the workpiece; the abrasive wheel being positioned in a position in translation along the third axis; and wherein the position in translation is determined as a function of a position and of an angular position of the workpiece around the first axis. The invention further related to a grinding machine for carrying out such method. |
US10207379B2 |
Live tool collar having wireless sensor
A live tool system having a live tool and a collar surrounding a rotating shaft or a rotating cutting tool of the live tool. The collar houses at least one sensor capable of monitoring an operating condition proximate to the cutting tool during a cutting operation. Example operating conditions including temperature and vibration. The system also includes a wireless transmitter in communication with the at least one sensor for transmitting a signal for use by a machining center controller. |
US10207372B2 |
Aluminum composite material and method for manufacturing aluminum composite material
An aluminum composite material includes a first metallic plate, a second metallic plate, and a matrix material that is interposed between the first metallic plate and the second metallic plate and is formed of aluminum powder. Gadolinium oxide particles are dispersed in the matrix material. |
US10207369B2 |
Method for forming a laser processed hole
A method for forming a laser processed hole in a workpiece configured by bonding a transparent first member formed of a first material and a second member formed of a second material. The method includes holding the workpiece by a chuck table with a side of the first member directed upward; applying a pulsed laser beam to the workpiece from the upward side of the first member; detecting a wavelength of plasma light generated by applying the pulsed laser beam to the workpiece; and controlling the laser beam according to a detection signal from the plasma light. The plasma is detected by: passing only the wavelength of plasma light generated from the first material, and detecting the plasma light generated from the first material and outputting a light intensity signal based on the detection. The processed hole extends entirely through the first member without melting the second member. |
US10207368B2 |
Laser cutting apparatus and laser cutting method
A laser cutting apparatus that cuts a workpiece by radiating a laser beam thereon. The laser cutting apparatus is provided with a laser entrance portion to which an optical fiber that transmits the laser beam is fixed and an optical system through which the laser beam radiated from the optical fiber fixed by the laser entrance portion passes. The laser entrance portion includes a moving portion that moves or tilts the optical fiber with respect to the optical system and a fixing portion that fixes the moved or tilted optical fiber with respect to the optical system. |
US10207364B2 |
Laser welding condition determination method and laser welding device
A method for determining a laser welding condition of the present disclosure includes a first step, a second step, and a third step. In the first step, workpiece information indicating characteristics of a workpiece is input. In the second step, laser information indicating characteristics of laser light is input. In the third step, a first welding condition is calculated based on the workpiece information and the laser information, and then displayed. The first welding condition is any one of a recommended laser power of the laser light, a recommended welding speed, a recommended welding pattern, an estimated strength of a welded portion, and an estimated weld depth of the welded portion. Furthermore, the workpiece information includes a joint shape of the workpiece. Thus, an optimum weld condition can be set while considering a shape of a joint in welding. |
US10207360B2 |
Determining deviations of an actual position of a laser machining head from a desired position
Implementations of the present disclosure include methods, systems, and computer-readable storage mediums for determining a deviation between an actual position and a desired position of a laser machining head of a laser machining machine. Implementations include actions of selecting at least two different machining positions of the laser machining head, in which a laser beam emitted by the laser machining head is directed onto a desired position of a workpiece, moving the laser machining head into a first selected machining position and forming a through-opening into the workpiece at or around the desired position by operation of the laser beam, moving the laser machining head into a second selected machining position and detecting radiation generated by an interaction between the laser beam and the workpiece, and determining whether there is a deviation between an actual position of the laser machining head and the desired position based on the detected radiation. |
US10207354B2 |
Indirect spot welding apparatus
In the indirect spot welding apparatus, a lower limit in a stable pressing force region where the pressing force of the spot welding electrode against the metal sheets can be controlled within a tolerance of ±10% ranges from 70 N to 200 N and an upper limit in the stable pressing force region ranges from 800 N to 2000 N, and an overshoot OS(%)=(PL−AL)/AL×100 of the pressing force occurring when the spot welding electrode is pressed against the metal sheets is controlled to be 10% or less. |
US10207350B2 |
Alternative power for engine driven welder
The invention described herein generally pertains to a system and method for a welding device and, in particular, a hybrid welding device, that leverages a renewable energy source for a source of electrical current. The welding device can include one or more renewable energy kits that harvest renewable energy sources for performing a welding operation or a powering at least one of a device or component external to the welding device. The welding device includes renewable energy component that collects an input to convert to an electrical current that can be used as a replacement current, a supplemental current, or a complimentary current. |
US10207343B2 |
Pipe isolation and intervention
A tool assembly configured for location on a section of a pipe is operable to both isolate a section of the pipe and perform an intervention into the pipe while maintaining pressure integrity. The tool assembly includes a clamp, a cutting tool and an isolation tool. In use, the clamp sealingly secures the tool assembly to the pipe, the cutting tool performs an intervention operation on the pipe, and the isolation tool isolates the section of pipe in order that repair or replacement of equipment can be effected. |
US10207340B2 |
Machining device for outer pipe surfaces
A machining device for machining the lateral surface of an approximately cylindrical object in portions thereof includes a chain for annularly surrounding the object to be machined. The chain consists of at least two hingedly connectable chain links, one of which is a tool holder having at least one tool for machining the lateral surface. The device also includes support rollers for rolling on the lateral surface. The at least one other chain link is a chain connecting link. The chain links are connectable in such a way that they form a closed chain ring around the object to be machined. The machining device further includes a feed adjuster capable of reversibly adjusting an axial position of facing ends of two chain links parallel to the axis of the closed chain ring relative to each other. |
US10207337B2 |
Front-loaded, side-activated modular drill
A front-loaded, side-activated modular drill includes a shank and a replaceable cutting insert installed on and engaging the tool shank. The shank has a pocket for supporting the cutting insert when the cutting insert is installed within the pocket. The pocket includes a first centering wall having an aperture with internal threads formed with a first pitch and a second centering wall having an aperture with a first portion with internal threads formed with a second, different pitch. A first member is threaded into the aperture of the first centering wall, and a second member is threaded into the second centering wall. The first member is threaded into the second member. The cutting insert has an opening in a trailing end for allowing the first member to pass therethrough. Rotation of the first member causes the centering walls to elastically deform and move relative to each other. |
US10207334B2 |
Vibratory machining device
A machining device including a framework, a transmission shaft and a drive mechanism including a rotation member for driving the shaft in rotation about its axis, a drive member in helical connection with the shaft to drive the translation thereof along its axis with a feed movement, according to the relative rotational speed of the rotation and drive members. The drive member is mounted with the ability to effect translational movement with respect to the framework along the axis and is positioned between the rotation member and an end for coupling of the shaft to a cutting tool, while an electromechanical actuator is mounted in a fixed frame of reference associated with the framework in front of the drive member to which it can be coupled in order to cause it to oscillate translationally so as to superpose an axial oscillation component with the feed movement. |
US10207332B2 |
Work holder and work machining method
A work holder includes: a first holding part having three attracting members that are arranged circumferentially apart from each other to attract an axial end face of an annular work; and a second holding part having a contacting member that is held in contact with an inner periphery or outer periphery of the work and restricts radial movement of the work. |
US10207327B2 |
Density enhancement methods and compositions
The present invention relates to granular composite density enhancement, and related methods and compositions. The applications where these properties are valuable include but are not limited to: 1) additive manufacturing (“3D printing”) involving metallic, ceramic, cermet, polymer, plastic, or other dry or solvent-suspended powders or gels, 2) concrete materials, 3) solid propellant materials, 4) cermet materials, 5) granular armors, 6) glass-metal and glass-plastic mixtures, and 7) ceramics comprising (or manufactured using) granular composites. |
US10207318B2 |
Electromagnetic brake system and method of controlling molten metal flow in a metal-making process
A method of controlling molten metal flow and an electromagnetic brake system for a metal-making process, including: a first magnetic core arrangement having a first and second long sides with Nc teeth, and arranged to be mounted to opposite longitudinal sides of an upper portion of a mould, a first set of coils, each being wound around a respective tooth of the first magnetic core arrangement, and Np power converters, with Np being an integer that is at least two and Nc is an integer that is at least four and evenly divisible with Np, wherein each power converter is configured to feed a DC current to its respective group of 2Nc/Np series-connected coils. |
US10207317B2 |
Additive manufacturing of semi-solid metal alloys using ultrasonic agitation
Apparatus, systems, and methods that ultrasonically agitate a semisolid metal slurry to prevent dendrite formation that can lead to clogging of a nozzle during direct metal writing. |
US10207311B2 |
Machine for the production of coiled gaskets
Machine (10) for the production of coiled gaskets from continuous strips, i.e. a master backing strip (1a) and sealing filler strip (1b), to be spirally wound onto rings, templates or inner rings (11), comprising at least: means (2) for feeding the strips (1a,1b) to be wound, a unit (100) for straightening and forming the backing strip (1a), a unit (200) for making incisions in and cutting the backing strip (1a), arranged downstream of the forming unit (100), a unit (300) for joining together the master strip (1a) and filler strip (1b) so as to form a combined strip (1) and cutting the filler strip (1b), a rotating spindle unit (400) for winding the combined strip (1), arranged downstream of the strip joining unit (300); a unit (500) for driving the ring or inner-ring (11) arranged downstream of the spindle (400), and a unit (600) for welding the master strip (1a), said units being designed to be able to produce automatically and in sequence a finished gasket, in accordance with a program managed by means (1000) for programming, controlling and actuating the operations. |
US10207305B2 |
Method of applying lubrication to legs of a hairpin tube
A method and system for manufacturing a hairpin tube. The method includes cutting a coil of tube to provide a plurality of lengths of tubes, and bending each length of tube to form a plurality of hairpin tubes. A lubricant is then atomized with an injector nozzle, and injected into at least one open end of each hairpin tube. After lubricating the hairpin tubes, the legs of each hairpin tube are expanded. |
US10207303B2 |
Cold rolling apparatus
A cold rolling apparatus includes: a heating device configured to heat a sequentially transferred steel sheet; a cold rolling mill configured to sequentially cold-roll the steel sheet after being heated; a meandering-movement correction device arranged on an upstream side of the heating device in a transfer direction of the steel sheet, and configured to correct a meandering movement of the steel sheet transferred toward the heating device; and a meandering-movement suppression device arranged between the heating device and the cold rolling mill, and configured to suppress a meandering movement of the steel sheet attributed to the cold rolling of the steel sheet by using the cold rolling mill. |
US10207301B2 |
Apparatus and method of for cleaning a thermostat in an internal combustion engine
A thermostat assembly for a marine engine, having a housing with a first bore and a second bore in communication with the first bore. A thermostat mounts within the first bore for movement between an open and a closed position. A plunger removably mounts within the second bore for movement between an extended position for engagement with the thermostat, and a retracted position for disengagement with the thermostat. |
US10207300B2 |
Ultrasonically clearing precipitation
A system for clearing precipitation from a window comprises one or more transducers (1-8) fixed to the window. The transducers are driven by a generator (13) to produce surface acoustic waves that propagate through the window. The window may be a laminated window such as a windscreen (10) for a vehicle. A sensing system (122) may be used for detecting the presence of precipitation to actuate the clearing system. |
US10207298B1 |
Cleaning apparatus for an air handling unit
An apparatus for supporting an air handling unit during servicing may comprise a support tray which defines a space for receiving the unit and may include opposite sides and opposite ends, with a front side and top of the tray being substantially open such that the is movable through the front side into the support tray. The apparatus may also include a support frame supporting the support tray above a ground surface and wheels on the support frame. The support frame may be configured to permit the tray to tilt end to end with respect to the support frame to adjust heights of the ends and to permit the tray to tilt side to side with respect to the support frame to adjust a height of the front side of the tray. |
US10207296B2 |
Material sorting system
A material sorting system sorts materials, such as scrap pieces composed of unknown metal alloys, as a function of their detected x-ray fluorescence. The x-ray fluorescence may be converted into an elemental composition signature that is then compared to an elemental composition signature of a reference material in order to identify and/or classify each of the materials, which are then sorted into separate groups based on such an identification/classification. The material sorting system may include an in-line x-ray tube having a plurality of separate x-ray sources, each of which can irradiate a separate stream of materials to be sorted. |
US10207291B2 |
Process for making a container with a resveratrol layer
A process for preparing a container for a liquid, wherein the process includes applying a coating layer, which includes a polymeric coating and a monomeric resveratrol additive, to an inner layer of a container wall. |
US10207286B1 |
Foam dispenser having twice automatic cleaning function
The present invention provides a foam dispenser having a twice automatic cleaning function that automatically discharges a compressed air toward a mixing chamber, when releasing a pulled trigger lever, thereby improving convenience of work and providing economic advantages. The foam dispenser having a twice automatic cleaning function includes a main body 4 including a hose connection unit 34 and an air hose connector 42, a coupling end part formed at the other end thereof, a pair of fluid passageways 20, an air passageway 22, and a handle 3; a dispensing nozzle 6 connected to the coupling end part of the main body 4, has a mixing chamber 64; a separate-fluid supply unit 8 provided inside the main body 4 to open or close the fluid passageways 20; and an automatic cleaner 10 provided at a middle portion of the air passageway 22 to automatically open the air passageway 22. |
US10207285B2 |
Fluid dispensing nozzle assembly
The current document is directed to a fluid dispensing nozzle assembly for use with a multi-well synthesizer and in other reagent distribution systems. In certain implementations, a fluid dispensing nozzle assembly comprises a nozzle body with a built-in dispenser tube, a reagent inlet tube, and a fitting that securely connects the inlet tube to the nozzle body. The nozzle body with the built-in dispenser tube and the reagent inlet tube are securely attached to one another by various coupling elements or adhesive material to ensure that liquid is transmitted through the inlet tube without leaking into the nozzle body and other undesired areas. |
US10207279B2 |
Sand separator vessel perforated replaceable insert apparatus and method
A perforated replaceable insert for a sand separator vessel in a digester feed system where the perforations have at least a width and a length. The perforations are aligned columns and rows, with the columns being positioned to be parallel to a line formed by the tangent of the conical axis. |
US10207277B2 |
Assessment and control of centrifuge operation
A drilling fluid conditioning system can include a centrifuge, and at least one heat transfer property sensor that outputs real time measurements of a heat transfer property of a drilling fluid that flows through the centrifuge. A method can include measuring a heat transfer property of a drilling fluid, and determining, based on the measured heat transfer property, an operational parameter of a centrifuge through which the drilling fluid flows. A well system can include a drilling fluid that circulates through a wellbore, and a drilling fluid conditioning system including a centrifuge and at least one heat transfer property sensor that measures a heat transfer property of the drilling fluid. |
US10207275B2 |
Iron ore concentration process with grinding circuit, dry desliming and dry or mixed (dry and wet) concentration
The present invention discloses an advantageous and effective process for the concentration of iron ores, which can be fully dry or mixed, part of the process being dry, part wet. The invention thereby improves process efficiency as a whole by increasing recovery of concentrators and increasing the useful life of the mines. |
US10207274B1 |
Non-forged hammermill hammer
Improved free-swinging hammermill hammer configurations are disclosed and described for comminution of materials such as grain and refuse. The hammer configurations of the present disclosure are adaptable to most hammer mill or grinders having free-swinging systems. The configurations as disclosed and claimed are non-forged and incorporate a saddle or hammer mouth. The merging of a hammer and saddle improves strength to reduce or maintain the weight of the hammer while increasing the amount of force delivered to the material to be comminuted. The improved configurations incorporate comminution edges having increased hardness for longer operational run times. The improved configurations improve installing, removing, and cleaning hammer components within the hammermill. The improved configurations may incorporate hammermill rod hole of varying shapes and sizes and saddles of varying shapes and sizes or the use of non-planar hammer bodies that have a recessed or protruding surface. |
US10207272B2 |
Method and device for placement of microscopic sample into the tube
The non-vertical tube holder enables visual control for transferring a microscopic sample into the test-tube, decreasing the chance of the sample loss. The tube holder may also be used for a tube transportation to the sample testing facility. |
US10207271B2 |
Benchtop nucleic acid library preparation device and methods for using the same
Complete nucleic acid library preparation devices are provided. Aspects of the devices include: a thermal chip module comprising multiple CLC reaction wells; one or more plate locations; a robotically controlled liquid handler configured to transfer liquid between the one or more plate locations and the thermal chip module; and a bulk reagent dispenser configured to access each CLC reaction well of the thermal chip module. |
US10207270B2 |
Identification of biological samples
A method for coding and identification of biological samples for in vitro fertilization comprises the steps of applying to receptacles intended for unfertilized eggs and sperm, respectively, an identification code characteristic of the patient; placing unfertilized eggs and sperm, respectively, in the receptacles; storing, transporting and admixing the respective samples in receptacles which each carry the same code; and implanting the resulting embryo in the patient. The identification code may based on RFID technology, in which sample vessels (12) are codified by the application of an RFID tag (13). |
US10207269B2 |
System and method for movement and timing control
The present invention relates to fluidic systems for controlling one or more fluids and/or one or more reagents. These systems can be used in combination with one or more devices for assaying, processing, and/or storing samples. In particular, the systems and related methods can allow for dispensing fluid in a controlled manner and/or introducing pause(s) when implementing assays or processes. |
US10207264B2 |
Functional device and method of manufacturing the same
A functional device (and a functional device manufacturing method) includes a first substrate in which a groove is formed in one surface, a second substrate which is integrally disposed by bonding one surface of the second substrate to the one surface of the first substrate, and forms a flow path together with the groove of the first substrate, at least one modification object of a capture body which captures a target substance supplied into the flow path, an electrode which imparts an electrical or a chemical action to the target substance, and a catalyst, in which the modification object is disposed by being modified on a part of an inner surface of the flow path, a bonding portion between the one surface of the first substrate and the one surface of the second substrate is formed by bonding fluorine to silica. |
US10207261B2 |
Photo-latent titanium catalysts
The present invention provides a photolatent Ti-chelate catalyst formulation, comprising (i) at least one compound of the formula (I) wherein R1 is C1-C20alkyl or C2-C20alkyl which is interrupted by one or more non-consecutive O-atoms; Y is formula (II) or optionally substituted phenyl; Y1 is formula (III) or optionally substituted phenyl; Y2 is formula (IV) or optionally substituted phenyl; Y3 is formula (V) or optionally substituted phenyl; R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 independently of each other are hydrogen, halogen, optionally substituted C1-C20alkyl, or R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 independently of each other are optionally substituted C6-C14aryl, provided that only one of R2, R3, R4 is hydrogen and only one of R5, R6, R7 is hydrogen and only one of R8, R9, R10 is hydrogen and only one of R11, R12, R13 is hydrogen; and (ii) at least one chelate ligand compound of the formula IIa, IIb or IIc, wherein Y′ is formula (VI) or formula (VII); Y′1 is formula (VIII) or formula (IX); R′2, R′3, R′4, R′5, R′6 and R′7 independently of each other have on of the meanings as given for R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13; and R′14, R′15 and R′16 independently of each other have on of the meanings as given for R14, R15 and R16. |
US10207260B2 |
Carbonylation catalyst and process
Carbonylation process for producing methyl acetate, by contacting dimethyl ether and carbon monoxide under carbonylation conditions in the presence of a catalyst having a zeolite of micropore volume of 0.01 ml/g. The zeolite is an as-synthesized organic structure directing agent-containing zeolite and contains at least one channel which is defined by an 8-member ring. |
US10207259B2 |
Hybrid SAPO-34/ZSM-5 catalyst, its preparation and its use
Prepare a hybrid SAPO-34/ZSM-5 catalyst via sequential steps as follows: a) form a mixture consisting essentially of ZSM-5 as a sole source of silicon atoms, aluminum isopropoxide and a solution of orthophosphoric acid; b) combine the mixture with an aqueous solution of tetraethylammonium hydroxide to form a reaction mixture; and c) subject the reaction mixture to hydrothermal conditions for a period of time sufficient to convert the reaction mixture to a hybrid SAPO-34/ZSM-5 catalyst. Use the hybrid catalyst in converting an oxygenate (methanol and/or dimethyl ether) to an olefin. |
US10207257B2 |
In-situ produced y-faujasite from kaolin-derived, pre-shaped particles and the method of preparation and the use thereof
A zeolite-containing fixed bed catalyst is formed by pre-shaping a mixture of a reactive aluminum-containing component and a matrix component into pre-shaped particles, and contacting the pre-shaped particles with a reactive liquid containing a silicate for a sufficient time and temperature to form an in-situ zeolite within the pre-shaped particles. The contacting of the pre-shaped particles and the liquid is achieved such that there is relative movement between the pre-shaped particles and the liquid. |
US10207255B2 |
Catalyst with improved activity/selectivity for light naphtha aromatization
In an embodiment, a method for making a catalyst, comprises: forming a mixture comprising a germanium source, an alkali metal source, an aluminum source, and a silica source, wherein the mixture has a pH; adjusting the pH of the mixture to a value of greater than or equal to 9.5; crystallizing and calcining the mixture to form a zeolite; depositing platinum on the zeolite; and calcining the zeolite to form the final catalyst. The final catalyst is non-acidic and has an aluminum content of less than or equal to 0.75 wt % based on the total weight of the final catalyst excluding any binder and extrusion aide and a Si:Al2 mole ratio of greater than or equal to 125. |
US10207254B2 |
Catalysed substrate monolith
A catalyzed substrate monolith 12 for use in treating exhaust gas emitted from a lean-burn internal combustion engine, which catalyzed substrate monolith 12 comprising a first washcoat coating 16 and a second washcoat coating 18, wherein the first washcoat coating comprises a catalyst composition comprising at least one platinum group metal (PGM) and at least one support material for the at least one PGM, wherein at least one PGM in the first washcoat coating is liable to volatilize when the first washcoat coating is exposed to relatively extreme conditions including relatively high temperatures, wherein the second washcoat coating comprises at least one metal oxide for trapping volatilized PGM and wherein the second washcoat coating is oriented to contact exhaust gas that has contacted the first washcoat coating. |
US10207250B2 |
Poly(meth)acrylic acid (salt)-based particulate absorbent
A low cost, a disposable diaper is provided that presents no difficulties in disposable diaper manufacture in humid climates, and that has a minimal amount of flowback, and rapid absorption time. A particulate water-absorbing agent is provided having as the principal component a poly (meth)acrylic acid (salt)-based water absorbing resin, wherein the water-absorbing agent has a particle size distribution of a weight average particle diameter of 300 to 500 μm, a blocking ratio after moisture absorption when left for one hour at 25° C. and 90% relative humidity of 20% or less, a surface tension of 60 mN/m or more, and a gel capillary absorption (GCA) of 28.0 g/g or more. |
US10207248B2 |
Methyl iodide adsorber, use thereof and method for the adsorption of methyl iodide
A methyl iodide adsorber, comprising a zeolite containing at least one iodide-adsorbing metal or a compound thereof, wherein the zeolite is a hydrophobic zeolite. Also, a use of the adsorber and a method for the adsorption of methyl iodide. |
US10207247B2 |
Device and method for heat and mass-exchange between gas and liquid
A device for heat, mass, and chemical exchange and interaction between gases and liquids. Nozzles feed the gas at angles in different directions to form a gas-liquid mix, swirls, and/or foam above an array of such nozzles. |
US10207245B2 |
Voltage application device and discharge device
A voltage application device according to the present disclosure includes a voltage application circuit and a control circuit. The control circuit causes the voltage application circuit to alternately repeat a first mode and a second mode. The first mode is a mode that raises a voltage while time elapses, and generates a discharge current by promoting corona discharge to dielectric breakdown. The second mode is a mode that lowers the voltage to cut off the discharge current by causing a load to be in an overload state against the voltage application circuit. This can suppress an amount of ozone generated, while increasing an amount of radicals produced. |
US10207243B2 |
Polymerization reactor and method for producing water absorbent resin
A polymerization reactor of the present invention includes a container body 1 and a jacket 2 covering the outer surface of the container body 1 and defining a passage for passing a cooling/heating medium between itself and the outer surface of the container body. The container body 1 is made of a clad metal plate including a support metal layer 11a having an inner surface at an inner side of the container body and an outer surface at an outer side of the container body, and an inner corrosion-resistant metal skin layer 11b bonded to the inner surface of the support metal layer and being smaller in thickness than the support metal layer. |
US10207241B2 |
Inductively heated microchannel reactor
The current document is directed to an efficient multi-channel chemical reactor having a multichannel core containing a plurality of parallel channels, with conductive walls, having a varying composition along their lengths. The channels are heated by a frequency-addressing different regions within the reactor with an inductive coil, driven by an agile frequency or spread spectrum emission controller. |
US10207239B2 |
Fluid distribution in a fluidized bed reactor
A fluid distribution cap (301) for a fluidized bed reactor, comprising a tunnel shaped structure having two opposing walls for attaching to a fluid distribution plate (103), and at least one opening at an end of the tunnel shaped structure. The tunnel shaped structure has an inner surface (302) and an outer surface (303), wherein the inner surface (302) has a curved cross section, and wherein the outer surface (303) has a substantially V-shaped cross section. A fluid distribution plate (103) for a fluidized bed reactor, comprising a plate having a plurality of fluid vent holes (113), a plurality of fluid distribution caps (301), wherein for each fluid vent hole (113) a fluid distribution cap (301) is mounted over said hole (113). At least two mutually neighboring fluid distribution caps (301) are positioned with an opening of a first of the two neighboring fluid distribution caps facing a side of the second of the two neighboring fluid distribution caps. A fluidized bed reactor having a fluid distribution plate (103) and a fluid distribution cap (301). |
US10207238B2 |
Catalyst composition with mixed selectivity control agent and method
The present disclosure provides a Ziegler-Natta catalyst composition comprising a procatalyst, a cocatalyst and a mixed external electron donor comprising a first selectivity control agent, a second selectivity control agent, and an activity limiting agent. A polymerization process incorporating the present catalyst composition produces a high-stiffness propylene-based polymer with a melt flow rate greater than about 50 g/10 min. The polymerization process occurs in a single reactor, utilizing standard hydrogen concentration with no visbreaking. |
US10207235B2 |
Process and device for the steam reforming and steam cracking of hydrocarbons
A furnace and a process for temperature control of a material stream, wherein the furnace has a first combustion chamber, at least one reactor tube for receiving the material stream to be heated, and at least one second combustion chamber. The at least one reactor tube extends through the first combustion chamber and through the at least one second combustion chamber. The furnace is designed to establish a first temperature in the first combustion chamber and a second temperature in the at least one second combustion chamber, wherein the first temperature and the second temperature are separately adjustable. |
US10207233B2 |
Apparatus for producing rapid-hardening concrete by intermixing and dissipating air in normal concrete and adding early-strength admixture thereto, and method for producing same
The present invention relates to an apparatus for producing rapid-hardening concrete and a method for producing same, the rapid-hardening concrete being produced by intermixing and dissipating air in normal concrete and adding an early-strength admixture thereto. With respect to forming rapid-hardening concrete, mixed concrete is formed by mixing in a large volume of air bubbles to be discarded, along with an early-strength admixture, to already mixed normal concrete, the early-strength admixture getting evenly dispersed therewithin by means of the ball bearing effect of the air bubbles, and when the mixed concrete is discharged, a rapid-hardening concrete is shotcreted while excess air contained in the mixed concrete is dissipated by means of high-performance air, the slump which was raised due to the large amount of air bubbles having been reduced to the slump range for normal concrete. |
US10207232B2 |
Dissolved hydrogen liquid-discharging pot and method for generating pressurized dissolved hydrogen liquid
A dissolved hydrogen liquid-discharging pot makes it easier for a user to use hydrogen water by making the pot capable of discharging or spraying a liquid in which hydrogen is dissolved continuously for a constant period at a prescribed pressure. The internal pressure of a pressure chamber, the volume of which has been subdivided by an indicator line on a pot body, is maintained with hydrogen, which is generated by a hydrogen-generating agent disposed in a hydrogen-generating section, at a discharge pressure that is sufficient to discharge all of the liquid inside a bottle section while an on-off valve that opens and closes a discharge tube is closed, and when the on-off valve is opened intermittently or continuously, at a pressure sufficient for continuing discharge of the liquid inside the bottle section and performing continuous discharge of dissolved hydrogen liquid until the bottom of the bottle section is reached. |
US10207228B2 |
Surface-modified separation membrane and method for modifying surface of separation membrane
A surface-modified separation membrane of the present invention comprises a separation membrane, and a coating layer formed on the surface of the separation membrane for improving the contamination resistance and chemical resistance of the separation membrane, wherein the coating layer is implemented with a nanoscale thickness of the coating layer in order to inhibit a decrease in permeation flux of the separation membrane before and after coating the coating layer, and comprises: dopamine for providing, to the coating layer, an adsorption force to be bound stably with the separation membrane; and a hydrophilic material which is bound to the dopamine through secondary bonding or cross-linking containing a hydrogen bond in order to inhibit the deterioration of the durability of the coating layer, and provides hydrophilicity to the surface of the separation membrane in order to protect the separation membrane from hydrophobic contaminants. A method for modifying the surface of a separation membrane of the present invention comprises the steps of: injecting a separation membrane to be surface-modified into a reactor; adding a mixture solution, which is formed by adding a hydrophilic material to a Tris-buffer solution having an adjusted pH range at which dopamine reacts and stirring the same, to the reactor; adding dopamine and an initiator, which induces the cross-linking of the hydrophilic material and dopamine, to the reactor at a predetermined temperature range; and forming a coating layer comprising dopamine and the hydrophilic material on the separation membrane through thermal cross-linking at the predetermined temperature range while injecting oxygen into the reactor. |
US10207225B2 |
Single-pass filtration systems and processes
The present invention provides, in various embodiments, hybrid single-pass tangential flow filtration assemblies, disposable single-pass tangential flow filtration assemblies, scalable single-pass tangential flow filtration assemblies and adaptable modular single-pass tangential flow filtration assemblies. In other embodiments, the invention relates to processes for recovering proteins from the surface of a filtration membrane in a single-pass tangential flow filtration assembly and for cleaning a tangential flow filtration assembly. In additional embodiments, the invention provides methods of increasing the processing capacity of a single-pass tangential flow filtration assembly. |
US10207223B2 |
Exhaust gas purifying device
An exhaust gas purifying device includes a first SCR catalyst converter, an oxidation catalyst converter, a filter section, and a second SCR catalyst converter arranged in series to a flow direction of an exhaust gas. The first SCR catalyst converter includes a pillar-shaped honeycomb structure a cell density of which is from 31 to 78 cells/cm2, a porosity of the partition walls of which is from 50 to 65%, and in which a first SCR catalyst is loaded onto the surfaces of the partition walls and inner portions of pores formed in the partition walls, and an amount of the first SCR catalyst to be loaded onto the surfaces of the partition walls and the inner portions of the pores is from 200 to 500 g/L and an amount of the first SCR catalyst to be loaded onto the inner portions of the pores is from 5 to 80 g/L. |
US10207220B2 |
Method and apparatus for removing sulfur oxides from gas
Methods, apparatus, and compositions for cleaning gas. The use of segmented multistage ammonia-based liquid spray with different oxidation potentials to remove sulfur compounds from gas. The use of different oxidation potentials may reduce unwanted ammonia slip. |
US10207218B2 |
Method for removing SOx from gas using polyol composite solution
A method for removing SOx from a gas by using a polyol composite solution is provided. The polyol composite solution is made by mixing a polyol with an organic acid and/or organic acid salt, the polyol composite solution is brought into contact with the gas containing SOx to absorb the SOx in the gas, wherein x=2 and/or 3, and the polyol refers to an organic compound other than ethylene glycol and polyethylene glycol, which contains simultaneously two or more than two hydroxyl groups in a same organic molecule. |
US10207217B2 |
Removal of hydrogen sulphide and carbon dioxide from a stream of fluid
A process for removing hydrogen sulfide and carbon dioxide from a fluid stream comprises a) an absorption step in which the fluid stream is contacted with an absorbent comprising an aqueous solution (i) of an amine of the general formula (I) in which R1, R2 and R3 are each independently selected from C1-4-alkyl and C1-4-hydroxyalkyl; each R4 is independently selected from hydrogen, C1-4-alkyl and C1-4-hydroxyalkyl; each R5 is independently selected from hydrogen, C1-4-alkyl and C1-4-hydroxyalkyl; X is OH or NH(CR1R2R3); m is 2, 3, 4 or 5; n is 2, 3, 4 or 5; and o is 0 or 1; and optionally (ii) at least one tertiary amine, where the molar ratio of (i) to (ii) is greater than 0.05; wherein at least 90% of the hydrogen sulfide is removed from the fluid stream and selectivity for hydrogen sulfide over carbon dioxide is not greater than 8, wherein a CO2- and H2S-laden absorbent is obtained; b) a regeneration step in which at least a substream of the CO2- and H2S-laden absorbent is regenerated and a regenerated absorbent is obtained; and c) a recycling step in which at least a substream of the regenerated absorbent is recycled into the absorption step a). The process allows a high level of hydrogen sulfide removal with a simultaneously high coabsorption of carbon dioxide. |
US10207216B2 |
Removal of dust in urea finishing
Disclosed is a method for the removal of urea dust from the off-gas of a finishing section (1) of a urea production plant, the method comprises subjecting the off-gas to quenching with water (06) so as to produce quenched off-gas, and subjecting the quenched off-gas to scrubbing using at least one venturi scrubber (11). As a result, a lower pressure drop over the scrubber is attained, and a more efficient growth of urea particles, facilitating the removal thereof. |
US10207213B2 |
Turbomachinery filter change forecaster
A method of monitoring a turbomachinery system is disclosed herein. The method includes measuring a pressure drop across an intake filter. The method further includes determining clog rate parameters for a clog rate of a filter area of the intake filter based on the measured pressure drop across the intake filter. The method yet further includes predicting an intake filter life cycle of the intake filter by predicting a pressure drop across the intake filter for the intake filter life cycle based on the determined clog rate parameters, and providing a recommended time to service the intake filter to an operator of the turbomachinery system based on the predicted intake filter life cycle. |
US10207210B2 |
High flow disc filter
A filter device is configured to filter a liquid. The filter device includes a drum sized to receive the liquid and a plurality of filter panels coupled to the drum to define a plurality of discs. The liquid passes through at least a portion of one of the discs. Each filter panel includes a perimeter frame that defines a panel normal flow area and a filter media coupled to the perimeter frame. The filter media may be adapted to include a plurality of pleats. |
US10207199B2 |
Methods of purifying cannabinoids using liquid:liquid chromatography
The present specification discloses methods of purifying one or more cannabinoids from a plant material, purified cannabinoids and pharmaceutical compositions comprising one or more cannabinoids produced by the disclosed method, methods and uses for treating a disease or condition employing such purified cannabinoids and pharmaceutical compositions. |
US10207197B2 |
Process for ambient temperature fractionation and extraction of various biomasses
The present invention provides a process for fractionating biomass into its individual components. The process includes pretreating a biomass which may include mechanically altering the fibers and/or contacting the biomass with a solvent to provide a fluidized biomass. The pretreated fluidized biomass may be subjected to high frequency pulses and shear forces without denaturing one or more components of the biomass to provide a first liquid fraction and a first fractionated biomass. The first liquid fraction may then be isolated or separated from the first fractionated biomass. The biomass may be separated, isolated or purified into lignin, extractives for use in pharmaceuticals or nutraceuticals, cellulose, hemicellulose, and other sugars and proteins. |
US10207190B2 |
Technologies for native game experience in web rendering engine
Technologies for web-based game execution include a computing device with a web rendering engine and a native game engine library. The web rendering engine establishes a scripting environment that issues calls to a game engine interface established by the web rendering engine. The scripting environment may be a JavaScript engine. In response to calls to the game engine interface, the game engine interface issues calls to the native game engine library. The native game engine library issues native graphics commands to a graphics bridge of the computing device. The native graphics commands may be OpenGL calls. The graphics bridge translates the native graphics commands to a web graphics context, which renders graphical game content to a web content element of the web rendering engine. The web graphics context may be a WebGL context, and the web content element may be a canvas element. Other embodiments are described and claimed. |
US10207189B1 |
System and method for determining type of player in online game
A system for determining a type of a player associated with an online game, wherein the system includes at least one player device having one or more sensing modules; a server arrangement communicably coupled with the at least one player device, wherein the server arrangement is configured to transmit a first set of information to the at least one player device; receive a second set of information from the at least one player device, wherein the second set of information comprises a game information and a sensor information; analyze the second set of information to calculate a reliability factor of the associated player; and determine the type of the associated player based on the calculated reliability factor. |
US10207188B2 |
Fantasy sports data analysis for game structure development
In an aspect, fantasy sports data is analyzed to generate and/or manage the delivery of and user experience of fantasy sports games and contests, including timing and payout structure(s) for short-term fantasy contests, such as daily, weekly, etc. fantasy sports contests, that motivate and appeal to contestants and is/are reasonably structured and concisely represented. In yet another aspect, a daily fantasy contest system is provided to automatically adjust to user demand without overshooting profitable levels and offer a variety of different contests, as well as offer contests with guaranteed and non-guaranteed payouts. |
US10207186B2 |
Method for controlling a user interface
In an embodiment there is provided a computer implemented method of providing a game, the method comprising the following implemented by at least one processor and at least one memory of a device retrieving from at least one memory information associated with a plurality of first objects and one or more characteristics of said first objects and causing said objects with said one or more characteristics to be displayed on a display in an arrangement, executing at least one algorithm which: responsive to detected user input rearranges said first objects to provide a sequence of at least three adjacent first objects sharing at least one same characteristic, determines an upgrade level of each of said at least three adjacent first objects, and in response to said determination selecting one of said at least three adjacent first objects for upgrading, and causes an updated arrangement to be displayed with said selected one of the said at least three adjacent first objects being upgraded and having said same characteristic and other of said three adjacent first objects being replaced with further first objects. A device and program are also provided. |
US10207181B2 |
Accessory for presenting information associated with an application
A system that incorporates teachings of the present disclosure may include, for example, an accessory having a plurality of tactile-sensitive buttons, a plurality of light sources, wherein each light source emits a controllable spectrum of light through a corresponding one of the plurality of tactile-sensitive buttons, and a controller coupled to the plurality of tactile-sensitive buttons, and the plurality of light sources. The controller can be operable to detect tactile contact of each of the plurality of tactile-sensitive buttons, receive status information associated with a video game, and adjust the spectrum of light emitted by at least a portion of the plurality of light sources according to the status information to indicate one or more aspects of the video game. Additional embodiments are disclosed. |
US10207180B2 |
Multi-player game input with detection of context and physical object usage
Systems, apparatuses and methods may provide for determining a state of a multi-player game and identifying a user communication associated with the multi-player game. Additionally, an outbound communication may be generated based on the user communication and the state of the multi-player game. In one example, generating the outbound communication includes conducting a weighted selection of one or more of a recipient, a content or an audio effect of the outbound communication based on the state. |
US10207178B2 |
Method of calibration for a video gaming system
A method of calibration a video game system can include removing an optical filter that filters out visible light from a field of view of a camera to allow the camera to view visible light. The method can also include displaying a calibration image on a display screen located within the field of view of the camera, processing the video output feed from the camera with a computer processor to identify the calibration image, and calculating with the processor coordinates that represent corners of the display screen in the field of view of the camera once the calibration image is identified. |
US10207176B2 |
Home-use crane game machine
There is provided a home-use crane game machine whose operation of a rotation transmission mechanism can be restored with ease that includes a plurality of motors 91, 92, 93 having a drive shaft to which a gear is fitted, rotation transmission mechanisms having a plurality of gears which are rotated by the plurality of motors 91, 92, 93, a catcher 65 for grabbing a prize 6 which is moved up and down by the rotation transmission mechanisms, a crane main body 54 having the motors 91, 92, 93 and the rotation transmission mechanisms internally, and rollers 68, 69, 70 connected to the rotation transmission mechanisms via input gear mechanisms. |
US10207160B2 |
Golf club heads
Some disclosed golf club heads include body having at least one raised sole portion and a cantilevered ledge extending down around a perimeter of the club head below the level of the raised sole portion. Some disclosed golf club heads include one or more sole openings in the body and a sole insert that is mounted inside the body over the sole openings. The sole can include weight tracks as well, and a rear weight track can extend between a toe side sole opening and a heel side sole opening. A crown insert can also be included that is mounted over an upper opening in the body. |
US10207158B2 |
Sports ball
A sports ball comprising a cover having an outer substrate surface is provided. The cover may include plurality of panels, wherein each panel has a respective panel surface. The panel surfaces of the respective panels collectively comprise the outer substrate surface of the cover. A surface texture is disposed upon and additively applied to the outer substrate surface. The surface texture is disposed on the respective panel surfaces in customizable, panel-specific, predefined panel arrangements. The surface texture defines surface profile that includes an alternating and repeating series of land areas and raised portions, wherein each raised portion is positioned between a plurality of land areas. The raised portions extend from the outer substrate surface and are formed from a dimensional ink, wherein each of the plurality of raised portions has a terminus that is spaced apart from the outer substrate a height of greater than about 0.05 millimeters (mm). |
US10207157B2 |
Golf balls having multi-layered cores with thermoset outer layer
Multi-piece golf balls containing a multi-layered core structure are provided. The core structure includes a small, heavy inner core (center) having a relatively high specific gravity, an intermediate core layer, and a surrounding outer core layer. The layers of the core structure may have different hardness gradients. In one preferred embodiment, each core layer has a positive hardness gradient. The center of the core comprises a metal material such as copper, steel, brass, tungsten, titanium, aluminum, and alloys thereof. The intermediate core layer is preferably formed from a first thermoset composition such as polybutadiene rubber, and the outer core layer is preferably formed from a second thermoset composition. The resulting ball has high resiliency and good spin control. |
US10207154B1 |
Sprayed polyurea covered golf ball
A golf ball with a cover formed by spraying is disclosed herein. In the present invention, a mixture of a low viscous diisocyanate component and a diamine free of organic solvent are sprayed onto a mantle insert to form a cover layer for a golf ball. A rapid reaction occurs and a solid layer forms within ten seconds. The polyurea material is extremely durable so that the cover layer performs with excellent shear cut durability. |
US10207143B2 |
Low profile collapsible treadmill
A manually operated treadmill a deck and a tread belt encircling the deck to provide a movable, continuous running surface during operation of the treadmill. Further, the treadmill includes a transmission connecting a flywheel to the tread belt and a resistance unit disposed to adjustably apply a resistance force to the inertial motion of the flywheel. |
US10207141B2 |
Hands-free middle back exercise apparatus
This invention relates to health and fitness and more particularly to exercise methods and devices. This invention is directly related to strengthening the muscles between the shoulder blades associated with poor posture, without the use of the hands. The exercise apparatus comprises two adjustable fabric loops connected to a rubber loop. The user slips one arm into each fabric loop pulling the device up to rest on the back of the upper arms with the rubber loop resting across the front of the body just above chest height. User then contracts the shoulder blades together and down which creates resistance on the rubber loop strengthening the muscles between the shoulder blades. |
US10207131B2 |
Anchorage connector for a safety system
An anchorage connector for use in a height safety system is provided. The anchorage connector comprises an energy absorbing, deformable, corrugated enclosed chamber having a first end and a second end, and at least one anchorage attachment point, at one end or both ends. |
US10207129B2 |
Face mask seal for use with respirator devices and surgical facemasks, having an anatomically defined geometry conforming to critical fit zones of human facial anatomy, and capable of being actively custom fitted to the user's face
The present disclosure is a face seal (FS) device for filtering face piece respirators (FFR) of all types, that corrects inner face seal leakage (FSIL) of particulate material that occurs due to well documented failures in FS designs of the prior art. The present disclosure differs from those of the prior art in having compensatory accentuations at locations along the entire 360 deg. FS inner perimeter that are based on specific details of facial human anatomy which are known to be sites of FSIL. The FS is also constructed of a heat activated thermoplastic copolymer that enables the device to be custom fitted to the user's face. Experimental data, confirmed with workplace protective factor (WPF) studies, show a 60-240 fold improved performance over FS designs of the prior art. |
US10207125B2 |
Methods, devices, and systems for treating bacteria with mechanical stress energy and electromagnetic energy
A portion of a treatment device for treating bacteria may be coupled with the bacteria through direct or indirect contact. Mechanical stress energy and electromagnetic energy are generated with the treatment device, and are transmitted from the treatment device to the bacteria during the coupling. The bacteria are treated with both the mechanical stress energy and the electromagnetic energy to produce a killing effect on the bacteria. A treatment device may include a mechanical stress energy emitting portion, an electromagnetic energy emitting portion, and a contacting portion for coupling into direct or indirect contact with the bacteria and transmitting mechanical stress energy to the bacteria during the coupling. The mechanical stress energy emitting portion and the electromagnetic energy emitting portion are operable to treat the bacteria with a combination of mechanical stress energy and electromagnetic energy to produce a killing effect on the bacteria. |
US10207122B2 |
Method and apparatus for electromagnetic enhancement of biochemical signaling pathways for therapeutics and prophylaxis in plants, animals and humans
Apparatus and methods for delivering electromagnetic signals configured specifically to accelerate the asymmetrical kinetics of the binding of intracellular ions to their respective intracellular buffers, to enhance the biochemical signaling pathways plant animal and human molecules, cells, tissues, organs, portions of entire organisms and entire organisms employ for growth, repair and maintenance. Described herein are devices and methods that utilize repetitive bursts of waveforms configured to maximize the bound concentration of intracellular ions at their associated molecular buffers to enhance the biochemical signaling pathways living systems employ for growth, repair and maintenance. For example the systems and methods described herein may drive the binding of calcium to calmodulin (CaM), thereby enhancing the CaM-dependent nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling pathway. |
US10207117B2 |
Wireless communication in an implantable medical device system
Embodiments presented herein are generally directed to techniques for the transfer of isochronous stimulation data over a standardized isochronous audio or data link between components of an implantable medical device system. More specifically, as described further below, a first component is configured to generate dynamic stimulation data based on one or more received sound signals. The first component is configured to obtain static configuration data and to encode the dynamic stimulation data and the static configuration data into a series of isochronous wireless packets. The first component is configured to transmit the series of wireless packets over an isochronous wireless channel to a second component of the implantable medical device system. |
US10207115B2 |
Method and systems for heart failure prevention and treatments using ultrasound and leadless implantable devices
The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts. |
US10207112B2 |
Cardiac therapy including vagal stimulation
Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes. |
US10207107B2 |
Electrostimulation apparatus
An electrostimulation apparatus may comprise a control unit, a power supply and a carrier separated or combined. The control unit is configured to provide the electrical current to an electrode layer settled on or inside the carrier, and the power supply is configured to heat a heating piece settled on or inside the carrier. The carrier has a plurality of connecting portions which are configured to electrically connect to the control unit, the power supply, the heating piece and the electrode layer. Furthermore, the electrode layer is electrically connected to the control unit through the connecting portions, and also the heating piece is electrically connected to the power supply through the connecting portions. Also, the heating piece and the electrode layer are attached on the carrier, and the carrier can be used to serve both training and treatment purposes for a user. |
US10207106B2 |
Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders
Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The methods provide damaged interstitial cells of Cajal (ICC) with trophic factors via vagal afferent nerve fibers, thereby reversing ICC damage, and as a consequence improving gastric motility. The methods also increase levels of inhibitory neurotransmitters in the brain so as to decrease neural activity within the area postrema, or they deactivate a resting state neural network containing parts of the anterior insula and anterior cingulate cortex, which will thereby reduce abnormal interoception and visceral hypersensitivity. |
US10207102B2 |
Methods and devices for activating brown adipose tissue using electrical energy
Methods and devices are provided for activating brown adipose tissue (BAT) using electrical energy. In general, the methods and devices can facilitate activation of BAT to increase thermogenesis. The BAT can be activated by applying an electrical signal thereto that can be configured to target sympathetic nerves that can directly innervate the BAT. The electrical signal can be configured to target the sympathetic nerves using fiber diameter selectivity. In other words, the electrical signal can be configured to activate nerve fibers having a first diameter without activating nerve fibers having diameters different than the first diameter. Sympathetic nerves include postganglionic unmyelinated, small diameter fibers, while parasympathetic nerves that can directly innervate BAT include preganglionic myelinated, larger diameter fibers. The electrical signal can be configured to target and activate the postganglionic unmyelinated, small diameter fibers without activating the preganglionic myelinated, larger diameter fibers. |
US10207101B2 |
System and method for suppressing vestibular activity of a human subject
A system for suppressing vestibular activity of a human subject includes an electronics module configured to generate one or more electrical stimulation signals. A plurality of electrodes each placed proximate a predetermined location on a head of a human subject is configured to deliver the one or more electrical stimulation signals to the predetermined location to suppress vestibular activity of the human subject. |
US10207098B2 |
Catheter devices and techniques
This application describes example antimicrobial compositions that may be used alone or in combination with catheters and catheter insertion sites. According to another aspect, the application describes catheters which may employ one or more protection devices, such as cleaning caps, protective caps or both. |
US10207095B2 |
Fast clear port
Described herein are implantable ports including a housing with a fluid receptacle, a port stem in fluid communication with the fluid receptacle, and a septum covering the fluid receptacle. The ports may be configured to reduce the priming volume by including a plurality of fluid-locked chambers and/or one or more base mats. The ports may also include a hydrophobic coating on one or more surfaces thereof. |
US10207094B2 |
Metallic microneedles
Methods for fabricating metallic microneedles are disclosed. One method comprises providing a mold pillar; forming an apertured electrically-conductive layer over the mold pillar; and depositing a metal layer over the electrically-conductive layer to provide an apertured microneedle. Another method comprises providing a mold pillar; depositing a first metal layer over the mold pillar to provide a first microneedle; removing the first microneedle from the mold pillar; and depositing a second metal layer over the mold pillar to provide a second microneedle. |
US10207083B2 |
Balloon catheter and method for manufacturing balloon
A balloon catheter includes a flexible elongated shaft and a balloon fixed to the distal portion of the shaft. The balloon expands and contracts. The balloon includes an effective expansion portion and at least one projection portion on the effective expansion portion. The effective expansion portion possesses a cylindrical shape when the balloon is expanded, and the projection portion extends for a predetermined length along the axial direction of the balloon. The projection portion has first and second parts so that the inner surface of the first part of the balloon faces the inner surface of the second part of the balloon. The first and second parts project radially outwardly away from immediately adjacent parts of the balloon. The inner surface of the first part of the balloon is at least partially welded to the inner surface of the second part of the balloon. |
US10207077B2 |
Medical device
A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member. |
US10207074B2 |
Float retention arrangement for humidification chamber
A float retention arrangement and related methods for a humidification chamber that includes at least one float that operates an inlet valve that controls a flow of water through a water inlet opening of the humidification chamber. A cover of the humidification chamber defines an interior space, at least one gas port and a float retention opening. A component forms at least a portion of a water supply conduit for supplying water from a water source to the water inlet opening. The component is insertable into the float retention opening and is positionable to contact and retain the at least one float in a non-use position. In some configurations, the component can be a water spike. |
US10207071B2 |
Nasal cannula
A nasal cannula arrangement for use as part of systems for delivery respiratory gases to a patient is disclosed. The nasal cannula arrangement includes a manifold part adapted to receive gases from a delivery conduit. The manifold includes one but preferably a pair of prongs extending upward and curving towards the rear of the manifold. The prongs are inserted into the nostrils of the patient and deliver gases to a patient. The prongs have a cut out on the rear side of the prongs. The cut out forms a gases outlet in the prongs and are shaped such that the area of the cut out area is greater than the cross sectional area of the prongs at the entry point to the prongs. |
US10207070B2 |
Seal forming portion, pad and cushion for a patient interface and method of manufacturing
It is discloses a patient interface 3000 comprising a seal forming portion 11, a pad 10, and a cushion 20. The seal forming portion 11 may comprise a base surface 111 and a plurality of fibers 112 fixed to and extending away from said base surface 111 for contacting a patient's skin. The cushion 20 may comprise at least along a portion of the circumference a first structure 22 having an elongate section 24 joined with at least one end section 26 oriented substantially perpendicular or at an angle to the elongate section 24. A first end A of the elongate section 24 may be connected or connectable to a frame member 30. The end section 26 may be provided at an opposing second end B of the elongate section 24. The pad 10 may comprise a resilient foam material layer with the seal forming portion 11. The pad 10 may be adapted to be connected to the cushion 20. |
US10207067B2 |
Blister advancement mechanism comprising an actuator plate
The present invention relates to improvements made in the blister advancement mechanism of dry powder inhaler devices. A dry powder inhaler device mechanism comprising an actuator plate and a transmission wheel is provided. |
US10207063B2 |
Nebulizer and spacer for the topical application of a liquid and/or solid to a surface
The present invention relates to a nebulizer, such as a spray can, for the topical application of a liquid and/or solid to a surface. The nebulizer is characterized by a valve comprising a mixing chamber designed for forming a colloidal mixture comprising a dispersed phase consisting of a liquid and/or a solid substance and a continuous phase consisting of a propellant gas before delivering the colloidal mixture to the nozzle. The invention also relates to a method for the topical cooling of the skin of a person or animal. In addition, the invention relates to various other uses of the device. |
US10207059B2 |
Device for receiving an injection syringe comprising a protective cap for the needle
A device for receiving an injection syringe, configured to receive an injection syringe including a needle and a protective cap for the needle. The receiving device has a distal end and includes a member for removing the protective cap, removably fastened onto the distal end of the receiving device, the removal member including a gripping section for gripping by a user and a catch on the cap, able to drive the cap when the removal member is removed from the receiving device, so as to strip the needle. An assembly including a receiving device and an injection syringe as well as a method for assembling a receiving device and an injection syringe. |
US10207058B2 |
Pen-type drug injection device with particular dose scale and dose display window comprising optical filter for unambiguous display of set dose value
The present invention relates to a pen-type drug injection device, comprising a dose scale drum (22) and having a housing (12) with a window (14) covered by an optical filter (50), the dose scale drum being displaceable axially relative to the housing during dose setting such that the dose value set can be read through the window while at least a portion of the dose scale drum protrudes from the housing. The dose values (42) are printed on an information surface (40) of the drum as an illegible pattern (48) together with a coding pattern (44), wherein the dose values (42) and the coding pattern (44) are designed such that light (52) reflected by or emanating from the illegible pattern (48) interacts with the optical filter (50) in such a way that the dose values (42) are exclusively recognizable through the optical filter (50) but not on the part of the dose scale drum protruding from the housing. The optical filter can be a color filter or a polarization filter in order to achieve the desired effect. In this way confusion of the actually set dose value and dose values which would otherwise be visible on the part of the dose scale drum protruding from the housing can be avoided during dose setting. |
US10207057B2 |
Syringe with rotatable element, systems including the syringe, and associated methods
A syringe includes a barrel and a rotatable element on the barrel, for example, at a proximal location along the length of the barrel. The rotatable element rotates at least partially around the barrel. When a handle is associated with the rotatable element, the barrel may rotate as the handle is held substantially stationary or the handle may be rotated while the barrel and any peripheral device secured thereto remain substantially stationary. When handles are associated with a rotatable element that may be removed from a barrel, a barrel that is disassembled from the rotatable element may be replaced with another barrel of the same or a different configuration. The barrel and plunger may be configured to cause the barrel to rotate as the plunger moves along the length of the barrel. Methods of using a syringe with a rotatable element on a barrel thereof are also disclosed. |
US10207056B2 |
Set of members for a drug delivery device, drug delivery device and set of drug delivery devices
A set of members for a drug delivery device comprises at least two components for the device, wherein both components are provided with a marking, the markings being substantially equivalent or identical. Furthermore, a drug delivery device and a set of drug delivery devices are provided. |
US10207055B2 |
Nozzle for use in an ultra-high velocity injection device
An exemplary embodiment of the invention is a nozzle, for use in an injection device, that projects material at an ultra-high velocity. The nozzle includes an integrally formed body having an interior passageway that has a longitudinal axis. The input of the nozzle is configured to interface with a cartridge, and the output is configured to be placed proximate to a target. The passageway includes a taper, and its path length, from an initial diameter to a position along the passageway where the passageway first reaches a smallest diameter, is at least 0.5 mm. The taper of the passageway defines a shape, in a plane that includes the longitudinal axis, that is a continuous and monotonically decreasing function of distance along the longitudinal axis in a direction of flow through the nozzle. |
US10207049B2 |
Single core pin assembly that creates two independent valve retainers for enteral feeding head
A single core pin assembly (10) having a first core pin (12) and at least one second core pin (14), the first core pin (12) having a first end (16), a second end (18) and a first core pin body (20). The first core pin body (20) connects the first end (16) and the second end (18). The second core pin (14) has a first end (24), a second end (26), and a second core pin body (28) connecting the second core pin first end (24) and the second core pin second end (26). The second core pin first end (24) is configured to join with the first core pin first end (16) to form a common downstream channel (30). The core pin (10) may be placed in a mold and surrounded by a flowable material (e.g. plastic) to form a work piece. |
US10207044B2 |
Five-port blood separation chamber and methods of using the same
Systems and methods are provided for separating blood into two or more separated blood components. The system includes a blood separation chamber with a single stage having five ports connected thereto. The five ports include a blood inlet port, a red blood cell outlet port, a platelet-rich plasma outlet port, a platelet-poor plasma outlet port, and a buffy coat outlet port. In the single stage, blood may be separated into a variety of components, such as red blood cells and platelet-rich plasma or red blood cells, platelet-poor plasma, and buffy coat. Depending on the components into which the blood is to be separated, flow out of one or more of the outlet ports may be prevented. |
US10207043B2 |
Solid-body catheter including lateral distal openings
A catheter for vascular insertion, including a catheter body defining a first lumen and a second lumen, and including a distal region. The distal region includes an atraumatic nose portion defining a first distal opening in fluid communication with the first lumen, and a second distal opening in fluid communication with the second lumen. The distal region also includes a first lateral opening defined by the catheter body and in fluid communication with the first lumen, and a second lateral opening defined by the catheter body and in fluid communication with the second lumen. One or both of the first and second lateral openings may be defined by an angle cross-cut through an outer perimeter of the catheter body. |
US10207041B2 |
Method and device to monitor patients with kidney disease
A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject. |
US10207040B2 |
Adjusting sound on a medical device
A dialysis machine comprising: a microphone; an alert module for producing an audible alert related to an operating condition of the dialysis machine; and a processing module configured for: receiving, from the microphone, information related to measured noise; determining, based on the information related to measured noise, an audible alert that will not be masked by the measured noise when the audible alert is produced by the alert module; and providing, to the alert module, instructions for producing the audible alert. |
US10207037B2 |
Cannula assembly
Cannula assemblies and methods of manufacturing cannula assemblies are provided. The cannula assembly includes a cannula and a pigtail extension coupled to the cannula. The pigtail extension includes a proximal section having a first stiffness and a distal section having a second stiffness, the first stiffness greater than the second stiffness. The proximal section of the pigtail extension is positioned between the cannula and at least a portion of the distal section. |
US10207036B2 |
Apparatus and method for securing and utilizing breast pumps using a person's legs
The various embodiments disclosed relate to straps that attach to manual breast pumps to allow the user to pump breast milk with leg power rather than by hand. One of two straps is wrapped around each of a user's thighs. Both straps have fasteners to enable the straps to be securely wrapped around the thigh. The straps are then connected to a manual breast pump. The breast pump can be connected to the manual breast pump by adding fasteners to the breast pump, or by threading the breast pump hoses through the pump connector. After the breast pump has been connected to the pump connectors, the user places the breast cup on their breasts. The user then begins pumping the manual pump by repeatedly moving their legs in an outward and inward motion. |
US10207034B2 |
Sleeves, manifolds, systems, and methods for applying reduced pressure to a subcutaneous tissue site
The illustrative embodiments described herein are directed to apparatuses, systems, and methods for applying reduced pressure to subcutaneous tissue site. In one illustrative embodiment, the apparatus includes a sleeve adapted for placement at a subcutaneous tissue site. The sleeve is further adapted to receive a manifold. The sleeve may also have an opening operable to transfer reduced pressure from the manifold to the subcutaneous tissue site. In one embodiment, the apparatus may also include a manifold that is insertable into the sleeve. The manifold may include at least one aperture, and may be operable to deliver reduced pressure to the subcutaneous tissue site via at least one aperture. |
US10207033B2 |
Sensor-controlled nasal aspirator
The present disclosure illustrates a sensor-controlled nasal aspirator including a distance sensing unit, a micro processing unit and an air pump. The distance sensing unit is configured to sense a distance between a target object and the distance sensing unit. The micro processing unit is configured to store a preset distance, and receive and process the distance transmitted from the distance sensing unit, and transmit an action command signal when the distance is not higher than the preset distance. The air pump is configured to receive the action command signal and performs a target action according to the action command signal. |
US10207031B2 |
Integrated system for assessing wound exudates
An integrated system for assessing wound exudates from the wound of a patient is described. The system may contain functionality to detect, process and report various wound parameters. The system also may make treatment determinations based on these findings. The system may detect one or more physiological values of the wound exudates from the wound of the patient. The system may means for comparing the one or more detected physiological values to predetermined physiological values in order to obtain a comparison result in real time. The system may include a processor 15 which provides an electronic signal based on a comparison result in which the electronic signal may correspond to guidelines for treating the wound 13. The system may be integrated with other wound treatment devices, such as negative pressure wound therapy devices (NPWT) 9. |
US10207029B2 |
Tissue filler compositions and methods of use
The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore. |
US10207021B2 |
Low sweel tissue adhesive and sealant formulations
A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized dextran containing pendant aldehyde groups with a multi-arm polyethylene glycol amine is described. The hydrogel exhibits little to no swell upon exposure to physiological conditions. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a low swell hydrogel to inhibit complications, such as fibrosis, including scar formation or surgical adhesions. |
US10207017B2 |
Deodorizer
A deodorizer includes: a body case having an inlet and an outlet opening outward and having an air duct that provides communication between the inlet and the outlet; a blowing fan included in the body case, for introducing indoor air into the air duct extending from the inlet to the outlet; deodorizing means provided in a middle of the air duct, through which the introduced air can pass; heating means placed to face at least a partial region of the deodorizing means, for heating the deodorizing means at 200° C. or less; and a controller for controlling operations of the blowing fan and the heating means. The deodorizing means includes, on a carrier, an adsorbent that does not oxidatively decompose an adsorbed material, a catalyst component that oxidatively decomposes the adsorbed material, and a rate of conversion of alcohol into acetic acid by the catalyst component is 15% or less on average across the entire deodorizing means. |
US10207014B2 |
Coated plant virus imaging agents
An imaging nanoparticle comprising a plant virus particle having an interior surface and an exterior surface, an imaging agent that is linked to the interior and/or exterior surface, and a layer of biocompatible mineral such as silica coated over the exterior surface, is described. The imaging nanoparticle can be used in method of generating an image of a tissue region of a subject, by administering to the subject a diagnostically effective amount of an imaging nanoparticle and generating an image of the tissue region of the subject to which the imaging nanoparticle has been distributed. |
US10207012B2 |
Non-invasive in vivo imaging and methods for treating type I diabetes
The present invention provides novel drug discovery platforms and methods for treating type I diabetes. |
US10207007B2 |
Conjugates of tumor necrosis factor inhibitors to functionalized polymers
This document relates to conjugates of TNF inhibitors or derivatives thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates. |
US10207004B2 |
Method for producing sweetener compositions and sweetener compositions
Provided herein are compositions with enhanced sweetness or reduced caloric content per weight when compared to the sweetener carbohydrate or sweetener polyol component thereof, and methods for the preparation thereof. |
US10206998B2 |
Modular targeted therapeutic agents and methods of making same
Provided herein are methods for making targeted therapeutics. In several embodiments, the therapeutics are directed against soluble agents such as toxins, venoms, and/or other factors that alter physiological biopathways as well as methods of using such therapeutics to treat patients or patient populations to reduce, eliminate, or inactivate, detrimental soluble agents that such patients or patient populations have been exposed to. In several embodiments, the therapeutics are directed to patient-specific disease markers. In several embodiments, the methods comprise screening a library comprising proteins linked to their cognate mRNAs to identify mRNA-protein pairs that bind to the diseased cells, isolating one or more proteins from the identified mRNA-protein pairs, and conjugating the isolated protein(s) to a therapeutic agent. |
US10206994B2 |
RNA virus attenuation by alteration of mutational robustness and sequence space
The application generally relates to the attenuation of a RNA virus or of a clone thereof and involves the alteration of sequence space, more particularly the reduction, of mutational robustness of said RNA virus or clone. The means of the application are more particularly dedicated to the attenuation of an infectious RNA virus or clone, for the production of immunogenic composition or vaccine. More particularly, the means of the application involve the replacement of codon(s) by different codon(s), which is(are) selected to differ by only one nucleotide from a codon STOP, more particularly by different but synonymous codon(s), which is(are) selected to differ by only one nucleotide from a codon STOP. |
US10206993B2 |
PCV/mycoplasma hyopneumoniae/lawsonia intracellularis combination vaccine
This invention provides a multivalent immunogenic composition including a soluble portion of a Mycoplasma hyopneumoniae (M.hyo) whole cell preparation; a porcine circovirus type 2 (PCV2) antigen; and a Lawsonia intracellularis antigen, wherein the soluble portion of the M.hyo preparation is substantially free of both (i) IgG and (ii) immunocomplexes comprised of antigen bound to immunoglobulin. |
US10206992B2 |
MDR E. coli specific antibody
The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) E. coli strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody. |
US10206991B2 |
Mycoplasma hyopneumoniae vaccine
This invention provides an immunogenic composition including the supernatant of a Mycoplasma hyopneumoniae (M.hyo) culture, wherein the supernatant of the M.hyo culture has been separated from insoluble cellular material by centrifugation, filtration, or precipitation and is substantially free of both (i) IgG and (ii) immunocomplexes comprised of antigen bound to immunoglobulin. |
US10206990B2 |
Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as pancreatic carcinoma. The invention discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against pancreatic and other cancers. |
US10206988B2 |
Xenoantigen-displaying anti-cancer vaccines and method of making
Compositions, methods of making, and methods of using, xenoantigen-displaying anti-cancer vaccines are described. |
US10206983B2 |
Methods and compositions for enhancing an immune response, blocking monocyte migration, amplifying vaccine immunity and inhibiting tumor growth and metastasis
Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an antigen. The invention also provides relate methods for amplifying vaccine immunity by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an vaccine. The invention also provides related methods of inhibiting tumor growth and metastasis by administering to an individual with cancer an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an anti-tumor preparation. In addition, related compositions comprising an ARB or a compound of Formula (I) and an antigen, vaccine, or anti-tumor preparation are provided. |
US10206982B2 |
Wound debridement compositions containing seaprose and methods of wound treatment using same
Wound debridement compositions containing the proteolytic enzyme Seaprose and use of such compositions in wound treatment for the enzymatic debridement of wounds. |
US10206981B2 |
Anti-inflammatory peptides and composition comprising the same
A peptide with anti-inflammatory activity is described, wherein the peptide comprises at least one amino acid sequence among SEQ ID NO: 2 to SEQ ID NO: 179, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The peptides that have at least one amino acid sequence of SEQ ID NO: 2 to SEQ ID NO: 179 shows outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising those peptides can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases. |
US10206975B2 |
Polypeptides binding to human complement C5
The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A X6 X7EID X11LPNL X16X17X18QW X21AFIX25X26LX28D, and ii) an amino acid sequence which has at least 86% identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatment. |
US10206972B2 |
Anti-vascular disease and antitumor pharmaceutical composition and use thereof
An anti-vascular diseases and antitumor pharmaceutical composition is provided in the present invention, and it includes effective ingredients including bleomycin antitumor antibiotic, adrenal glucocorticoid, epinephrine or pharmaceutically acceptable salts thereof in a weight ratio of (1-8):(2-5):(0.00005-0.001). The pharmaceutical composition provided can be used for treatment of vascular diseases and tumors. |
US10206965B2 |
Carotenoid formulation
The present invention discloses the use of a lycopene coated with a water non-soluble thin film comprising amphiphilic protein polymer for coloring with red color, foods, pharmaceuticals or cosmetics having fat and/or oil contents higher than 5%. The invention further discloses a process for the preparation of stable lycopene formulation comprising (a) treating an isolated protein to form a protein in a molecular form; (b) dispersing lycopene in an aqueous solution comprising an isolated protein in a molecular form; (c) grinding said dispersion to form lycopene particle size of 1 to 10 μm forming an homogenized mixture comprising fine particles; and optionally (d) drying the homogenized mixture. |
US10206964B2 |
Synergistic anti-inflammatory compositions comprising Boswellia serrata extract
The present invention discloses synergistic nutraceutical or pharmaceutical or dietary supplement anti-inflammatory compositions comprising therapeutically effective combination of an extract selectively enriched in 3-O-acetyl-1 1-keto-β-boswellic acid (AKBA) derived from Boswellia serrata and Boswellia serrata non-acidic resin extract (BNRE). The composition(s) can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, endothelial dysfunction and the like. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases. |
US10206961B2 |
Process for preparing metabolized conditioned growth media
Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition. |
US10206956B2 |
Compositions and methods for reducing frequency and/or severity of headache
In one embodiment, the present invention relates to a method for reducing the frequency and/or severity of headache in a subject comprising administering to the subject a composition comprising the stromal vascular fraction or stromal cells of adipose tissue. In another embodiment, the present invention relates to a method for reducing the frequency and/or severity of headache in a subject comprising administering to the subject a composition compositing bone marrow. In another embodiment, the present invention relates to a method for reducing the frequency or severity of headache in a subject comprising administering to the subject a composition comprising adult stem cells. |
US10206950B2 |
Preparation of a cell concentrate from a physiological solution
The present invention is directed to methods and compositions regarding the preparation of an cell concentrate, such as, for example, an osteogenic cell concentrate, from a physiological solution, such as bone marrow aspirate, blood, or a mixture thereof. In specific embodiments, the invention provides methods and compositions utilizing two physiological solution-processing techniques, particularly in a point of care environment, wherein centrifugation is not employed. |
US10206936B2 |
Oxidized lipids and treatment or prevention of fibrosis
The present invention is directed to methods of treating or preventing fibrosis comprising an oxidized lipid or pharmaceutical composition comprising the same. |
US10206932B2 |
Natural combination hormone replacement formulations and therapies
Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the pharmaceutical composition comprises solubilized estradiol, suspended progesterone, and a solubilizing agent comprising a medium chain (C6-C12) oil. |
US10206931B2 |
Therapeutic compounds and uses thereof
The present invention relates to compounds of formula (I): and to salts thereof, wherein A has any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders. |
US10206929B2 |
3-(1H-imidazo[4,5-c]pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. |
US10206928B2 |
Method of maintaining oral health in animals
Use of a compound having the formula (I) in a medicament for the prevention or treatment of a disease caused by oral bacteria in an animal wherein R1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, or a pharmaceutically acceptable salt thereof. |
US10206926B2 |
Quinazoline compounds
Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and methods of using and making such compounds. |
US10206925B2 |
Topical formulations of PDE-4 inhibitors and their methods of use
Embodiments herein are directed to topical formulations of a compound represented by the formula (I), salt, metabolite, prodrug, or hydrate thereof along with a solvent, and a base. The compound is a PDE4 inhibitor and the topical formulations may be used to treat dermatological conditions such as, but not limited to, atopic dermatitis, seborrheic dermatitis, alopecia, contact dermatitis, psoriasis, urticaria, eczema, burns, sunburn, pancreatitis, hepatitis, lichen planus, scleritis, scleroderma, dermatomyositis, itching associated with any of the preceding conditions or a combination thereof. |
US10206923B2 |
Pharmaceutical composition of alogliptin and metformin
Present invention relates to a stable pharmaceutical composition comprising intimate mixture of alogliptin and metformin, and suitable pharmaceutically acceptable excipient/s; wherein metformin is present in about 3.3 parts or more parts by weight relative to 100 parts by weight of the total weight of part comprising alogliptin. Invention also encompasses various processes of preparing said pharmaceutical composition and its use in improving glycemic control in adults with type 2 diabetes mellitus. |
US10206922B2 |
Substituted pyrimidines for treatment of chronic cough, neuronal hypersensitivity underlying chronic cough, neuronal hypersensitivity underlying sub-acute cough and neuronal hypersensitivity underlying acute cough
Methods for treating cough, chronic cough and urges to cough associated with respiratory diseases with a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein. |
US10206916B2 |
Cabozantinib salts and their use as anti-cancer agents
The present invention relates to crystalline forms of cabozantinib succinate (Form A) and cabozantinib acetate (Form A-1) and to pharmaceutical compositions comprising said crystalline forms and their use as anti-cancer medicaments. |
US10206914B2 |
Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation
Methods of treating, preventing and/or managing cancer as well as and diseases and disorder associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed. |
US10206913B2 |
4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds
The invention relates to compounds of formula I: where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds. |
US10206908B2 |
3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
6-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 6-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. |
US10206905B2 |
Use of composition for preparing a medicament for treatment of amyotrophic lateral sclerosis
The present invention relates to the use of a composition for preparing a medicament for the treatment of amyotrophic lateral sclerosis and associated disorders. The composition comprises 3-methyl-1-phenyl-2-pyrazoline-5-one or pharmaceutically acceptable salts thereof and borneol. The medicament is a drug used for delaying the occurrence time of amyotrophic lateral sclerosis and extending the survival time, and for improving memory function defect of amyotrophic lateral sclerosis. |
US10206902B2 |
Mono- or di-substituted indoles as dengue viral replication inhibitors
The present invention concerns mono- or di-substituted indole compounds of formula (I) which are useful to prevent or treat dengue viral infections and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds. |
US10206897B2 |
Creatine ester anti-inflammatory compounds and formulations
The present invention provides a creatine ester anti-inflammatory compound which may be received by animals and then metabolized into a biologically active form of creatine. The biologically active creatine inhibits the production of chemical mediators, released during an inflammatory response, which are important components in the inflammatory response and the inflammation and pain resulting from physical or chemical trauma to cells and tissue. |
US10206896B2 |
Method of treating delayed healing of a wound associated with diabetes
The method of treating delayed healing of a wound associated with diabetes includes administering to the wound a composition comprising an anti-senescence compound and a pharmaceutically acceptable carrier. The anti-senescence compound may be 18α-Glycyrrhetinic acid, a Caveolin-1 (Cav-1) inhibitory compound, or a Polymerase I Transcript Release Factor (PTRF-1) inhibitory compound. The anti-senescence compound may be effective in preventing and/or reversing premature cellular senescence. The anti-senescence compound may be effective in promoting healing of a wound, e.g., delayed or incompletely healed wound. The anti-senescence compound may be effective in promoting healing of a delayed healing wound or chronic wound of a diabetic patient, such as a diabetic ulcer or venous ulcer. |
US10206894B2 |
Compounds for use in treatment of mucositis
The present invention provides methods for treating and/or preventing mucositis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same. |
US10206893B2 |
Immunoregulatory agents
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided. |
US10206890B2 |
Pharmaceutical combination
A composition of matter comprising in combination as component (a) at least one 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol compound, and as component (b) at least one antiepileptic, a pharmaceutical formulation and a dosage form comprising said composition of matter, and a method of treating pain, e.g. neuropathic pain, in which components (a) and (b) are administered simultaneously or sequentially to a mammal, whereby component (a) may be administered before or after component (b) and whereby components (a) or (b) are administered to the mammal either via the same or a different pathway of administration. |
US10206887B2 |
Prion free nanoparticle compositions and methods of making thereof
The present invention provides prion-free compositions comprising nanoparticles comprising albumin and substantially water insoluble drugs. Also provided are methods of making prion-free compositions and methods of removing prion proteins from the nanoparticle compositions. Methods of using the compositions, as well as kits useful for carrying out the methods are also provided. |
US10206879B2 |
Active ingredient containing stabilised solid forms and method for the production thereof
The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate. |
US10206877B2 |
Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases
The present invention features compositions comprising a plurality of therapeutic agents wherein the presence of one therapeutic agent enhances the properties of at least one other therapeutic agent. In one embodiment, the therapeutic agents are cystic fibrosis transmembrane conductance regulators (CFTR) such as a CFTR corrector or CFTR potentiator for the treatment of CFTR mediated diseases such as cystic fibrosis. Methods and kits thereof are also disclosed. |
US10206873B1 |
Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
Methods of making a dry powder, comprise (a) delivering a liquid solution or suspension and a second, immiscible fluid to a flow path, (b) transporting the liquid solution or suspension and the immiscible fluid along the flow path, wherein the flow path includes two or more flow passages of different diameters, at least one flow divider which divides and diverts the flowing mixture into at least two separate passages, wherein the separate passages subsequently intersect to combine their respective flows into a single flowing stream, (c) rapidly reducing the pressure of the single flowing stream, whereby droplets are formed, and (d) passing the droplets through a flow of inert drying gas to form a dry powder. A nebulizing nozzle includes an inlet, a flow path as described, and a restrictor nozzle outlet. |
US10206870B2 |
Topical composition containing glycerin and yeast extract
The present invention provides a topical composition comprising (a) 0.5 to 25 weight percent of glycerin; (b) 0.1 to 5 weight percent of cetearyl olivate; (c) 0.1 to 5 weight percent of sorbitan olivate; and (d) 0.01. to 1 weight percent of extract of Pichia anomala; wherein the composition is substantially free of fatty alcohols and is in the form of a gel cream. |
US10206868B2 |
Topical compositions
The present invention relates generally to methods and compositions useful to cleanse, exfoliate, smooth, moisturize, hydrate, and/or improve the appearance and/or condition of skin and/or hair using a composition including shea butter, PEG-50 shea butter, and/or hydrated silica. |
US10206866B2 |
Nail compositions containing silicone-organic polymer hybrid compound
The invention relates to nail compositions comprising at least one silicone-organic polymer hybrid compound. |
US10206863B2 |
Cationic arabinoxylans, their hydrophobically modified products, and preparation method and application thereof
The present invention provides a cationic arabinoxylan and the hydrophobically modified product thereof. The cationic arabinoxylan is prepared based on a cereal arabinoxylan and a quaternizing agent, with water as solvent and strong alkali as catalyst. The hydrophobically modified product is prepared based on cationic arabinoxylan and alkyl halide, with pyridine as catalyst. Said cationic arabinoxylan and the hydrophobically modified product thereof can be used as a conditioning agent or thickener in cosmetics or personal care compositions, and can also be used in textile, papermaking, pharmaceutical and food industry applications. |
US10206862B2 |
Supplement to support healthy hair, skin, and nails
A supplement composition formulated to support the health of a human's hair skin and nails containing biotin, Haematococcus pluvialis algae, and Reishi. |
US10206861B2 |
Compositions containing natural extracts and use thereof for skin and hair
The present disclosure relates to compositions containing a natural extract(s) and their fraction(s) and the use of such compositions for treatment of skin, hair and nail. For example, the present disclosure relates to compositions containing an aqueous extract of (i) Yacon leave, (ii) Amor Seco leave, or (iii) Porphyridium biomass, or a combination thereof and a pharmaceutically or cosmetically acceptable carrier use on hair skin and nails for cosmetic purposes. |
US10206859B2 |
Cosmetic composition
A finisher composition in the form of an oil-in-water emulsion. The continuous aqueous phase of the emulsion is from about 20 to 85 wt % of water. The dispersed oil phase of the emulsion includes a non-volatile oil, which is at least 50% by weight of a liquid UV agent. The composition also includes from about 10 to 25 wt % of substantially spherical starch particles, silicone elastomer particles, or a combination of these. The particles have a particle size of from about 2 to 40 microns. The weight ratio of the non-volatile oil to the particles is from about 1:10 to about 1:1. The composition is substantially free of glycerin and, optionally, includes from about 1 to 20 wt % of a volatile oil. |
US10206858B2 |
Aluminum chlorohydrate salts exhibiting high SEC peak 1
Aluminum chlorohydrate salts having an amount of Peak 1 material relative based on a total of Peaks 3, 4, and 5 of at least 20% as measured by size exclusion chromatography, together with water treatment compositions, antiperspirant compositions, and oral care compositions, comprising the same, and methods for making and using the same. |
US10206857B2 |
Dental primer composition having adhesive property to resin cured material
A primer composition for a resin cured material according to the present disclosure comprising (A) a polymerizable monomer having a solubility parameter (an SP value) in the range of from 7.0 to 10.0, (B) a volatile organic solvent, (C) a polymerization catalyst and/or a polymerization accelerator, and (D) a polymerizable monomer having at least two polymerizable group. |
US10206851B1 |
Child-resistant, senior-friendly package
A child-resistant package is provided having a hollow carton with opposed front and rear walls and a separate blister card having a plurality of separate, spaced-apart hollow blister compartments contained therein. The front wall of the hollow carton comprising a structure including an exterior wall panel having a plurality of openings, gates, or pull tabs and an interior wall panel adhesively secured to the exterior wall panel. The interior wall panel of the front wall has a plurality of chads aligned between the openings and blister compartments. The rear wall of the hollow carton comprising a structure including an exterior wall panel having a plurality of separate, openings and an interior wall panel adhesively secured to the exterior wall panel. The interior wall panel of the rear wall having a plurality of break-away chads located directly between the blister compartments and the openings. |
US10206848B2 |
Beauty instrument
A beauty instrument capable of imparting a massaging effect to skin. A beauty instrument is configured such that a pair of balls is supported at the tip of a handle. The balls are positioned at a distance from each another, and are capable of rotating around respective axes thereof. |
US10206847B1 |
Portable rehab station
A portable rehab station, including left and right outriggers, each having a forward end and a rearward end, the left and right outriggers being pivotally connected at the bottom ends of the respective left and right frame members to pivot between retracted and expanded positions, the retracted position including the left and right outriggers being generally mutually parallel, and the expanded position including the left and right outriggers being spread out at an angle of between about six and ten degrees relative to each other; a front, ground-engageable caster connected to the forward end of each of the left and right outriggers and a rear, ground-engageable caster connected to the rearward end of each of the left and right outriggers; and an actuator assembly connected with the frame and operably connected with the left and right outriggers to selectively pivot the left and right outriggers between the retracted and expanded positions. |
US10206845B1 |
Calf stretching apparatus
A calf stretching apparatus having a base having a lower surface defining a lower surface plane, a front end, a rear end opposing the rear end of the base, the rear end of the base having a rear edge defining a recessed base through opening and a foot placement platform with a front end, a rear end opposing the front end of the foot placement platform, a platform surface spanning in an upward direction with respect the base from the front end of the foot placement platform to the rear end of the foot placement platform and disposed at an acute angle with respect to the lower surface plane, a platform sidewall surrounding the platform surface on three sides thereof, wherein the rear end of the foot placement platform has a rear edge defining a recessed platform through opening aligned with the recessed base through opening. |
US10206844B2 |
Interface for adjusting the motion of a powered orthotic device through externally applied forces
A lower extremity orthosis, including at least one actuator configured to control a motion of at least one joint of a person wearing the orthosis, is provided with a handle including a force sensor configured to produce a signal representing a force applied to the handle. A controller, which is in communication with the force sensor and the at least one actuator, is configured to modify the motion based on the signal from the force sensor. The system can be particularly employed to enable a physical therapist to have input in controlling and modifying the positions and/or forces prescribed by the lower extremity orthosis during rehabilitation of the person. |
US10206843B2 |
Patient positioning system
Described herein are exemplary embodiments of patient positioning systems for supporting and positioning a patient in an inclined position during medical treatment, such as in the Reverse Trendelenburg position. Some embodiments comprise a flexible, air-impermeable shell having a torso portion configured to support the patient's torso and secure the positioner to the support surface, an intermediate portion integrally coupled to an inferior end of the torso portion, and a suprapubic portion integrally coupled to an inferior end of the intermediate portion opposite the torso portion and configured to extend along the patient's perineal-pubic region when the shell is evacuated of air. When evacuated of air, the positioner is configured to hold the patient in an inclined position on an inclined support surface with the patient's head above the patient's hips such that the intermediate and/or suprapubic portions physically block the patient from sliding feet-first down the inclined support surface. |
US10206842B2 |
Medical table with leg support
A patient support apparatus, comprising a patient support having one or more pads for supporting a patient's torso and hip in a generally horizontal orientation. At least one, elongated leg support extends from the patient support. The leg support is movable through a generally horizontal plane. A portion of the leg support is declinable and inclinable from the horizontal plane. A traction device is connected to the leg support. The traction device is attachable to a patient's leg and operable to exert a traction force on the patient's leg along an axis generally parallel to the leg support. The traction device is connected to the leg support by a slide assembly and the traction device can be secured stationary relative to the leg support or the traction device can slide relative to the leg support. |
US10206841B2 |
Actuation system for controlling the movement of a table
An actuation system having a table, a lifting column for raising and lowering the table, first and second actuators pivotally mounted to a top section of the lifting column. The first and second actuators are coupled to a first end of the table. A guide plate having a top portion and at least one track is provided. The at least one track is slidingly engaged with at least one guide, the at least one guide is vertically mounted to a third side of the lifting column. The top portion of the guide plate is vertically driven by the third actuator and is universally coupled to a second end of the table. A controller for controls the movement of the lifting column in the vertical plane, and of the table in the longitudinal and lateral planes by varying the position of the three actuators relative to each other. |
US10206840B2 |
Incubator with buffer
A bed is stably mounted on a body when located at a first position. The bed is mounted on the body via buffering members so that the buffering members absorb and prevent vibration and shock from being transmitted from the body to the bed, when located at the second position. |
US10206838B2 |
Incubator
An incubator of the disclosure is configured such that a top hood is detachable from a peripheral frame by unlatching first latch mechanisms that latch the top hood. The incubator is also configured such that any of wall portion among four wall portions configuring the peripheral frame are detachable from an incubator base by unlatching any of corresponding second to fifth latch mechanisms. |
US10206837B2 |
Hospital bed and room communication modules
A system for use with a hospital bed having circuitry and a standard AC power outlet spaced from the hospital bed is provided. The system includes a cable assembly couplable to the circuitry of the hospital bed. The cable assembly has power conductors and at least one data conductor. The cable assembly also has a plug including a first power coupler coupled to the power conductors and a first data coupler coupled to the at least one data conductor. The system also includes a second data coupler mountable adjacent the standard AC power outlet. The second data coupler is configured to couple to the first data coupler when the first power coupler is coupled to the standard AC power outlet. |
US10206834B2 |
Obstruction detection system and method
Systems and methods for detecting a pinch event or obstruction to a movable component of a patient support. In some embodiments, the patient support apparatus may include a control system capable of controlling one or more actuator systems coupled to one or more movable components of the patient support apparatus. The control system may operate according to one or more modes of operation in controlling the actuator system to move a component from a first position to a second position. In one embodiment, the control system may receive sensor feedback indicative of one or more operating characteristics of an actuator system, and analyze the sensor feedback differently in one mode than in another. In one embodiment, the controller may receive sensor feedback indicative of both a speed of a component coupled to the movable component and a current of power supplied to an electric motor of the actuator system. |
US10206833B2 |
Assist chair
An assist chair includes a base portion, a pair of armrests, a backrest, an uplifting apparatus, a seat cushion and a waist rest cushion, wherein the uplifting apparatus further includes a pair of assist handles. When the uplifting apparatus is activated, the assist handles is capable of being driven out of inner sides of the pair of armrests, leaving the inner sides of the armrests or being retracted back to the inner sides of the pair of armrests after being pushed out of the armrests, such that the configuration can support the elderly when standing up or sitting down. |
US10206829B2 |
Fleece for sustained release of an active substance
The invention relates to the use of a fleece composed of plastic filaments, in particular made of a thermoplastic, as a sustained-released system or as a storage system for at least one active substance, in particular for at least one active liquid. The filaments are spun using a spinneret, and the plastic material of the filaments is foamed so that pores are formed at least on the surface or in surface regions of the filaments and at least some of the pores are pores that are open outward, and at least some of the open pores are filled with the active substance, in particular with the active liquid. |
US10206828B2 |
Breathable and liquid impermeable web and method of making the web
A method is disclosed for modifying the physical characteristics of a web which involves passing the web between at least one pair of interengaged rolls to incrementally stretch the web, and then withdrawing the incrementally stretched web from between the rolls under tension. A web modified according to the disclosed method has desirable breathability and liquid impermeability, as well as extensibility and a soft, cloth-like textured surface. |
US10206826B2 |
Three-dimensional substrates
A liquid permeable substrate for an absorbent article is disclosed. The substrate includes a first layer including a hydrophobic material and a second layer including a hydrophilic material. The first layer is joined to the second layer. The substrate includes a plurality of recesses, a plurality of projections, and a plurality of land areas. The land areas surround at least a majority of the plurality of projections and a plurality of the recesses. The plurality of recesses, the plurality of projections, and the plurality of land areas together form a first three-dimensional surface on a first side of the substrate and a second three-dimensional surface on a second side of the substrate. The substrate has an overall z-directional height in the range of about 1000 μm to about 6000 μm according to the Overall Substrate Height Test. |
US10206821B2 |
Eustachian tube dilation balloon with ventilation path
An apparatus comprises a shaft, an expandable dilator, and at least one ventilation pathway. The shaft defines a longitudinal axis and comprises a distal and proximal ends with at least one shaft lumen. The expandable dilator comprises body with its own proximal and distal ends. The body is configured to transition between a contracted state and an expanded state. The body is configured to dilate a Eustachian tube of a patient in the expanded state. The at least one ventilation pathway is configured to provide ventilation from the distal end of the body to the proximal end of the body when the body is in the expanded state. In some examples, the ventilation pathway comprises a set of transversely oriented vent openings formed through the shaft. In some other examples, the ventilation pathway comprises a space defined between one or more radially outwardly protruding features of the expandable dilator. |
US10206820B2 |
Epidermal down-growth barrier
A percutaneous implant for reducing the risk of post-implant infection by reducing the likelihood of epidermal down-growth between the dermis of the skin and the implant. In one example, the implant comprises a barrier member between the epidermis and the dermis about the implant. In another example, a barrier is provided by removing a portion of the epidermis from the dermis about the implant. |
US10206818B2 |
Patient interface for ophthalmologic diagnostic and interventional procedures
An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device. |
US10206816B2 |
Capsulotomy device
A surgical device and procedure for accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position. A cutting element mounted to the suction cup is used to cut a portion and to remove the portion. The cutting element may be mounted to a cutting element support structure in a way that prevents heating of the device. |