最新美国发明专利第2019-01-08期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US10174297B2	Fatty acid desaturases from primula The invention relates generally to methods and compositions concerning desaturase enzymes that modulate the number and location of double bonds in long chain poly-unsaturated fatty acids (LC-PUFA's). In particular, the invention relates to methods and compositions for improving omega-3 fatty acid profiles in plant products and parts using desaturase enzymes and nucleic acids encoding for such enzymes. In particular embodiments, the desaturase enzymes are Primula Δ6-desaturases. Also provided are improved soybean oil compositions having SDA and a beneficial overall content of omega-3 fatty acids relative to omega-6 fatty acids.
US10174296B2	Microorganisms engineered to use unconventional sources of phosphorous or sulfur Disclosed are genetically engineered organisms, such as yeast and bacteria, that have the ability to metabolize atypical phosphorus or sulfur sources. Fermentation methods using the genetically engineered organisms are also described. The fermentation methods are robust processes for the industrial bioproduction of a variety of compounds, including commodities, fine chemicals, and pharmaceuticals.
US10174295B1	Composition of matter: engineering of Escherichia coli phage K1E The present disclosure provides compositions including recombinant K1E bacteriophages, methods for making the same, and uses thereof. The recombinant K1E bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
US10174293B1	Recombinant PB1 bacteriophages and uses thereof The present disclosure provides compositions including recombinant PB1 bacteriophages, methods for making the same, and uses thereof. The recombinant PB1 bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
US10174289B2	Methods and systems for converting precursor cells into gastric tissues through directed differentiation Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells.
US10174286B2	Pancreatic islet-like cell structures and a method of preparing thereof The invention relates to a method of preparing pancreatic islet-like cell structures characterized by a unique combination of morphological and functional features which make them particularly suitable for use in both clinical and drug screening application, as well as to the pancreatic islet-like cell structures obtained therefrom.
US10174283B2	Method for cleaning water dispensers via use of selectively bred and cultivated generations of microbes Systems and methods for cleaning a water dispenser by preparing a bioremediation solution with microbes, a growth medium, and water; injecting the bioremediation solution into a water supply; and flushing the water supply with the bioremediation solution.
US10174279B2	Apparatus and method for expanding skin An embodiment of the present invention provides an apparatus and method for expanding skin capable of expanding autologous skin to the maximum extent and performing a tissue culture of skin at the outside of the body. While an apparatus for expanding autologous skin of body's outside in general takes a form of expanding skin by applying a certain amount of constant force for a period of time regardless of the skin properties, the apparatus and method for expanding skin according to the embodiment of the present invention expands the skin to the maximum extent without rupturing the skin based on measurements of elasticity of the skin to find the maximum expanded area reachable just before rupturing of the skin.
US10174273B2	Fabric softener composition The present invention then concerns a fabric softener composition that performs well on softening fabrics, which comprises a blend of amphoteric surfactant carrying a C12-C22-alkyl or C12-C22-alkenyl, a fatty acid or a fatty alcohol, and a polysaccharide or polysaccharide derivative. The invention also concerns the use of said softening composition to impart fabric softness to fabrics.
US10174264B2	Process for the production of white oils from waste oils The present invention describes a process for the production of technical white oils or edible or medicinal oils from waste oils originating from industrial use or engine use, said process using a deep hydrotreatment.
US10174259B2	Conversion of solid biomass into a liquid hydrocarbon material The present invention provides a process for producing liquid hydrocarbon products from a solid biomass feedstock, said process comprising the steps of: a) providing in a first hydropyrolysis reactor vessel a first hydropyrolysis catalyst composition; b) contacting the solid biomass feedstock with said first hydropyrolysis catalyst composition and molecular hydrogen in said first hydropyrolysis reactor vessel to produce a product stream comprising partially deoxygenated hydropyrolysis product, H2O, H2, CO2, CO, C1-C3 gases, char and catalyst fines; c) removing said char and catalyst fines from said product stream; d) hydroconverting said partially deoxygenated hydropyrolysis product in a hydroconversion reactor vessel in the presence of one or more hydroconversion catalyst and of the H2O, CO2, CO, H2, and C1-C3 gas generated in step a), to produce a vapor phase product comprising substantially fully deoxygenated hydrocarbon product, H2O, CO, CO2, and C1-C3 gases.
US10174253B2	Liquid crystal composition and liquid crystal display device A liquid crystal composition has the nematic phase and contains a specific compound having large positive dielectric anisotropy as a first component, a specific compound having small viscosity as a second component, and may contain a specific compound having high maximum temperature or small viscosity as a third component, a specific compound having large positive dielectric anisotropy as a fourth component or a specific compound having negative dielectric anisotropy as a fifth component, and a liquid crystal display device includes the composition.
US10174252B2	Liquid crystal composition and liquid crystal display device A liquid crystal composition has a negative dielectric anisotropy and contains a specific compound having large negative dielectric anisotropy as a first component, and a specific compound having small viscosity as a second component. The composition may contain a specific compound having high maximum temperature or small viscosity as a third component, a specific compound having negative dielectric anisotropy as a fourth component, or a specific compound having a polymerizable group as an additive component.
US10174250B2	Composition and process for metallizing nonconductive plastic surfaces The present invention relates to a composition of an etching solution and a process for metallizing electrically nonconductive plastic surfaces of articles using the etching solution. The etching solution is based on a stabilized acidic permanganate solution. After the treatment with the etching solution, the articles can be metallized.
US10174246B2	Red-emitting nitride-based calcium-stabilized phosphors Red-emitting phosphors may comprise a nitride-based composition represented by the chemical formula MaSrbSicAldNeEuf, wherein: M is at least one of Mg, Ca, Sr, Ba, Y, Li, Na, K and Zn, and 02+d/v and v is the valence of M. Furthermore, nitride-based red-emitting phosphor compositions may be represented by the chemical formula MxM′2Si5-yAlyN8:A, wherein: M is Mg, Ca, Sr, Ba, Y, Li, Na, K and Zn, and x>0; M′ is at least one of Mg, Ca, Sr, Ba, and Zn; 0≤y≤0.15; and A is at least one of Eu, Ce, Tb, Pr, and Mn; wherein x>y/v and v is the valence of M, and wherein the red-emitting phosphors have the general crystalline structure of M′2Si5N8:A.
US10174241B2	Methods for improving the distribution of a sealant composition in a wellbore and treatment fluids providing the same Methods for forming a fluid seal in a subterranean formation may comprise: providing a treatment fluid comprising an aqueous carrier fluid, a sealant composition, and a crosslinked polysaccharide composition. The treatment fluid is introduced into a wellbore penetrating a subterranean formation and the crosslinked polysaccharide composition is formed into a viscosified gel in the wellbore. The viscosified gel substantially spans the diameter of the wellbore and holds the sealant composition in place. After forming the crosslinked polysaccharide composition into a viscosified gel in the wellbore, forming a fluid seal in the wellbore with the sealant composition.
US10174240B2	Hydrocarbon well treatment methods and fluids A treatment method for a hydrocarbon well includes placing a well treatment fluid containing a viscosifying agent in the well and, using the viscosifying agent, attaining a first viscosity of the fluid in the well. The method includes combining a porphyrin compound with the fluid and, using the porphyrin compound, decreasing viscosity of the fluid in the well to a second viscosity less than the first viscosity. A hydrocarbon well treatment fluid includes an aqueous carrier fluid, a polymer viscosifying agent, and a chlorophyll compound.
US10174235B2	Low global warming potential binary refrigerant mixture with comparable energy efficiency to R-134a and a lower heat of combustion The present invention provides a binary refrigerant mixture that can be used in single or dual evaporator refrigeration systems to provide for efficient cooling without the use of a high global warming potential (GWP) hydrofluorocarbon refrigerant such as R-134a and that is less flammable than a hydrocarbon refrigerant such as R-600 (n-butane) or R-600a (isobutane). Further, the binary refrigerant mixture can be classified as an A2 refrigerant in that it has a heat of combustion of less than 19 kilojoules per kilogram. In addition, the binary refrigerant mixture has a comparable energy efficiency when compared to R-134a and can be used in refrigeration systems designed for use with R-600 or R-600a refrigerants without having to change their design (i.e., without having to change the compressor design).
US10174233B2	Reactive hot-melt adhesive composition A reactive hot-melt adhesive composition that is moisture curable contains: a urethane prepolymer having an isocyanate group, a (meth)acrylic resin, and an adhesion promoter containing at least an isocyanate group-containing (meth)acrylamide compound.
US10174232B2	Polyurethane adhesive layers for electro-optic assemblies Electro-optic assemblies and related materials (e.g., adhesive) for use therein are generally provided. The adhesive layer may comprise an end-capped polyurethane. Some adhesive layers comprise two or more reactive functional groups (e.g., reactive functional groups configured to react with one or more curing species such that, for example, at least one of the two or more functional groups forms a crosslink). The adhesive may also comprise a chain-extending reagent that includes one or more reactive functional groups. In some embodiments, the adhesive is cured by reacting one or more reactive functional groups with one or more curing species. Curing the adhesive may comprise two or more curing steps. In some embodiments the adhesive layer may comprise one or more cross-linkers.
US10174228B2	Amorphous poly alpha olefins of low acid and organoleptic properties and a process for producing same A process for reducing unreacted monomers and condensable and non-condensable hydrocarbon fractions in an APAO which includes introducing molten APAO into heated and insulated jacketed pipe while injecting a stripping agent based on the total weight of the contents of the jacketed pipe; maintaining the stripping agent with the molten APAO stream from ten seconds to ten minutes, forming a flowable heated mixture at 250 to 450 degrees Fahrenheit in the heated and jacketed pipe forming a flowing heated mixture; and passing the flowing heated mixture through a thin film evaporator assembly, while maintaining the temperature of the flowing heated mixture, stripping the organoleptic species and acids and volatile organic components from the flowing heated mixture and removing and recovering a condensable fuel fraction and a non-condensable hydrocarbon gas with energy, while simultaneously forming an odor-reduced, cleaned molten APAO-based HMA.
US10174226B2	Adhesive composition and semiconductor device using same An adhesive composition comprising silver particles containing silver atoms and zinc particles containing metallic zinc, wherein the silver atom content is 90 mass % or greater and the zinc atom content is from 0.01 mass % to 0.6 mass %, with respect to the total transition metal atoms in the solid portion of the adhesive composition.
US10174225B2	Adhesive composition An adhesive composition, capable of achieving excellent life performance and a wide margin for mounting, includes a cationic polymerizable compound, an aluminum chelate/silanol-based curing catalyst, and a nucleophilic compound containing a sulfur atom having an unshared electron pair. The nucleophilic compound is a thiol compound or an episulfide compound. The aluminum chelate/silanol-based curing catalyst includes an aluminum chelate curing agent, and a silanol compound or a silane coupling agent. The aluminum chelate curing agent constitutes a latent aluminum chelate curing agent carried by a porous resin obtained through interfacial polymerization of a polyfunctional isocyanate compound.
US10174224B2	Adhesive composition for touch panel, adhesive film, and touch panel Provided is a urethane adhesive composition for a touch panel having a glass transition temperature between −20° C. to −50° C., and which, as a cured composition, has an elasticity of 50,000 Pa to 70,000 Pa at 60° C. to 80° C.
US10174222B2	Flexible display device and method for preparing hard coating polymer of same A flexible display device includes a hard coating layer, the hard coating layer including hard coating oligomers, cross-linking oligomers that couple the hard coating oligomers, and a photoinitiator, the cross-linking oligomers being synthesized by catalytically reacting cross-linking monomers. The hard coating layer may include long cross-linking oligomers that improve the flexibility of the hard coating layer, and damage to the hard coating layer may be prevented or reduced even when the flexible display device is bent.
US10174220B2	Coated film According to the present invention, there is provide a coated film that is excellent in surface hardness and abrasion resistance and has good adhesion between a polyester film and a hard coat layer. The present invention relates to a coated film comprising a polyester film and a coating layer formed on at least one surface of the polyester film, the coating layer being prepared from a coating solution comprising a (meth)acrylate compound, a reactive silica comprising a (meth)acryloyl group, and an isocyanate-based compound.
US10174214B2	Detergent for gentle removal of inks and markers The invention relates to a detergent for gentle removal of inks as used for marking in a roll mill, and to markers as used in production for temporary marking. According to the invention, the problem is solved by a detergent which permits the gentle removal of inks or markers from metallic surfaces in the form of a concentrate or a cleaning bath solution containing at least one water-immiscible solvent in an amount of 4 to 200 g/l, at least one anionic and/or nonionic surfactant in an amount of 8-300 g/l, at least one complexing agent in an amount of 1-100 g/l, at least one buffer substance in an amount of 1-100 g/l and at least one water-miscible solvent in an amount of 4-200 g/l in water.
US10174212B2	Method for producing a pigment paste, aqueous electrocoat material, use thereof, method for cataphoretic electrocoating, and coated article The invention relates to a method for producing a pigment paste and an electrocoat containing the paste, the past being made by mixing solid pigment particles with a grind resin in the presence of water and/or an organic liquid, wherein the grind resin includes a dispersion of core-shell particles in an epoxide prepolymer which is liquid at 20° C. and the core-shell particles have a silicone core and a polymer shell.
US10174211B2	Conductive paste with improved performance in glass strength Silver pastes including two powders having different physical properties and silver flakes together with glass frits and pigments impart improved thermal stress characteristics to substrates upon firing.
US10174210B2	Method of fabricating high-conductivity thick-film aluminum paste The present invention provides an aluminum (Al) paste. The Al paste has low cost and high conductivity. An Al powder having a wide range of particle size distribution and an increased solid content are used to solve the problem of multiple pores. A rupture mechanism of alumina is fully used for sintering to improve contacting internal liquid Al with each other for forming conductive paths. With coordination of sufficient liquid glass powder, all ruptured surface of the Al powder is coated to inhibit exposed liquid Al from oxidation on contacting air. The problem of low conductivity of Al paste is thus radically solved.
US10174207B2	Metal surface coating composition and terminal fitted electric wire A metal surface coating composition and a terminal-fitted electric wire which is anti-corrosion treated with the composition are provided. The composition includes a high-consistency material containing a lubricant base oil and an amide compound, a composition of a phosphorus compound containing one or more compounds represented by the below formulae and a metal, and a nucleating agent: where X1 to X7 each represent an oxygen atom or a sulfur atom, R11 to R13 each represent a hydrogen atom or a hydrocarbon group having 1 to 30 carbon atoms, among which at least one is a hydrocarbon group having 1 to 30 carbon atoms, and R14 to R16 each represent a hydrogen atom or a hydrocarbon group having 1 to 30 carbon atoms among which at least one is a hydrocarbon group having 1 to 30 carbon atoms.
US10174202B2	Dyes with phosphinic acid, phosphinate, phosphonate and phosphonamidate substituents as auxochromic groups and methods for preparing the same Compounds of formula I are disclosed: wherein X1, X2, X3, X4 are independently H, F, Cl, Br, I, CN, NO2, OR1, SR1, NR1R2, COR1, COOR1, CONR1R2, PO3R1R2, SO2R1, SO3R1 or R3; R1 and R2 are, e.g., H, alkyl or aryl or optionally a ring; R3 is, e.g., alkyl, alkenyl, alkynyl, aryl or cycloalkyl; Y is OR1, NR1R2, or NR1R3; Q is O, S, SO2, NR, C(R3)2, Si(R3)2, Ge(R3)2, P(═O)R3 or P(═O)OR3; Q and X1 can optionally form part of a ring; L and M are independently OR1, SR1, NR1R2 and R3; L and M can optionally form part of a ring; Z is O, S, NR1, CR1R3 or aryl; and Z and X4 can optionally form part of a ring.
US10174201B2	Crosslinked products prepared by ionically crosslinking a solid grade oligomer and a polymer using an ionic crosslinking agent and methods of making the same Disclosed herein are compositions comprising a crosslinked product prepared by ionically crosslinking a solid grade oligomer and a polymer using an ionic crosslinking agent. In some embodiments, the polymer is derived from a hydrophobic monomer and/or a gas-phase mono-mer. In some embodiments, the solid grade oligomer is reacted with a polymer comprising a hydrophobic monomer and/or a gas-phase monomer. The present disclosure also relates to methods of making the disclosed compositions. The compositions disclosed herein can be used in a variety of applications including, but not limited to, asphalt compositions, paints, coatings, carpet compositions, paper binding and coating compositions, foams, or adhesives.
US10174196B2	Resin composition and molded article A resin composition contains: 60 to 95% by mass of polyphenylene ether (A); 35 to 0% by mass of styrene-based resin (B); and 15 to 5% by mass of elastomer component (C). The component (C) is present as dispersion particles in the resin composition. The dispersion particles have a number average particle size of 0.04 to 0.25 μm.
US10174192B2	PVC-free surface covering A PVC-free surface covering comprises at least one layer of a thermoplastic composition. The composition comprises a polymer matrix and at least one filler. The polymer matrix comprises at least one ionomer and/or at least one acid copolymer; and at least one styrenic thermoplastic polymer.
US10174188B2	Polypropylene composition The invention is directed to a polypropylene composition, to a three-dimensional article comprising said polypropylene composition, and to the use of said composition for automotive articles. The polypropylene composition of the invention comprises: —40-90% by total weight of the composition of a polymer blend comprising polypropylene having a melt flow index as measured according to ISO 1133 at 230° C. and 2.16 kg of 2.0-100 g/10 min; —5-25% by total weight of the composition of one or more plastomers; —0.5-25% by total weight of the composition of mineral filler selected from the group consisting of phyllosilicates, mica or wollastonite; and —0.2-4% by total weight of the composition of glass fibers having an average fiber diameter in the range of 5-30 μm.
US10174185B2	Pneumatic tire Provided is a pneumatic tire including a base tread formed from a rubber composition that can highly improve fuel economy, wet grip performance, and abrasion resistance while maintaining the balance between them. The pneumatic tire includes a base tread formed from a rubber composition, the rubber composition containing predetermined amounts of an isoprene rubber, a specified hydrogenated terpene resin, and a specified carbon black.
US10174181B2	Transfer film, method for manufacturing film sensor, film sensor, front panel and sensor assembly, and image display device A transfer film for forming a decorative layer on at least one surface of a film sensor has a coloring composition layer containing a black or white pigment, and the coloring composition layer satisfies inequality 1: 50>a×b>10 inequality 1 where a is the mass content ratio of the black or white pigment in the coloring composition layer, and b is the thickness of the coloring composition layer having a unit of μm.
US10174176B2	Chitin nanowhisker composites and methods A composite is provided that is formed by melt-blending particles of thermoplastic polymer that have been coated with a chitin nanowhisker gel, wherein the thermoplastic polymer comprises acrylonitrile butadiene styrene. A composite comprising chitin nanowhiskers dispersed in acrylonitrile butadiene styrene is also provided.
US10174174B2	Water-absorbing resin particles, absorber comprising same, and absorbent article Provided are the following: water-absorbing resin particles with which an absorber can be manufactured, the absorber enabling ample anchoring to be obtained without compromising on water absorbency; and an absorber obtained by anchoring together the water-absorbing resin particles and a fibrous base material. The present invention is: core-shell water-absorbing resin particles constituted of a core layer (P) containing a water-absorbing resin (A) and a shell layer (Q), the shell layer (Q) containing a thermoplastic resin (B) having a melting point of 50 to 180° C., and the thermoplastic resin (B) being a polymer having a hydrophobic block comprising a polyolefin; an absorber obtained by anchoring the water-absorbing resin particles to a fibrous base material (F); and an absorbent article made using such absorber.
US10174173B2	Polymerized in-situ hybrid solid ion-conductive compositions Provided herein are methods of forming solid-state ionically conductive composite materials that include particles of an inorganic phase in a matrix of an organic phase. The methods involve forming the composite materials from a precursor that is polymerized in-situ after being mixed with the particles. The polymerization occurs under applied pressure that causes particle-to-particle contact. In some embodiments, once polymerized, the applied pressure may be removed with the particles immobilized by the polymer matrix. In some implementations, the organic phase includes a cross-linked polymer network. Also provided are solid-state ionically conductive composite materials and batteries and other devices that incorporate them. In some embodiments, solid-state electrolytes including the ionically conductive solid-state composites are provided. In some embodiments, electrodes including the ionically conductive solid-state composites are provided.
US10174169B2	Moisture curable compound with metal-arene complexes The present invention provides curable compositions comprising non-tin metal accelerators that accelerate the condensation curing of moisture-curable silicones/non-silicones. In particular, the present invention provides an accelerator comprising metal-arene complexes that are suitable as replacements for organotin in sealant and RTV formulations.
US10174168B2	Composition for forming passivation film, including resin having carbon-carbon multiple bond There is provided a composition for forming a passivation film that satisfies electric insulation, heat-tolerance, solvent-tolerance, and a dry etch back property at the same time. A composition for forming a passivation film, including: a polymer containing a unit structure of Formula (i): T0-O Formula (i) (where T0 is a sulfonyl group, a fluoroalkylene group, a cycloalkylene group, or an arylene group having a substituent, or is a combination of an arylene group optionally having a substituent and a fluoroalkylene group or a cycloalkylene group), wherein the polymer has at least one of a group having a structure of Formula (2-A), a group having a structure of Formula (2-B), or a group having both of the structures, at an end, in a side chain, or in a main chain of the polymer: The polymer may contain a unit structure of Formula (1): L1-O-T1-O Formula (1)
US10174163B2	Non-aqueous crosslinkable composition a method to produce same and coatings and articles comprising the same A non-aqueous crosslinkable composition comprising a polyurea having a functionality of equal to or greater than 2; an aldehyde or acetal or hemiacetal thereof; and optionally one or more organic solvents is provided. Further provided is a crosslinked composition, a coating, articles including the coating and a method of making a non-aqueous crosslinkable composition.
US10174161B2	Transformation of meso-lactide B/N Lewis pairs have been discovered to catalyze rapid epimerization of meso-lactide (LA) or LA diastereomers quantitatively into rac-LA. The obtained rac-LA can be kinetically polymerized into poly(L-lactide) and optically resolved D-LA, with a high stereoselectivity factor kL/kD of 53 and an ee value of 91% at 50.6% monomer conversion, by a bifunctional chiral catalyst. The epimerization and enantioselective polymerization can be coupled into a one-pot process for transforming meso-LA directly into poly(L-lactide) and D-LA.
US10174157B2	Biodegradable aliphatic-aromatic polyester Disclosed are biodegradable aliphatic-aromatic polyesters obtained from aliphatic dicarboxylic acids, polyfunctional aromatic acids and diols, wherein the polyfunctional aromatic acids are constituted by mixtures of acids of renewable and synthetic origin its esters. In particular, the polyfunctional aromatic acids comprise at least one phthatic diacid and at least one heterocyclic aromatic diacid of renewable origin, which can be 2,5-furandicarboxylic acid and its esters. Also, provided are mixtures of the polyesters with other biodegradable polymers both of natural and synthetic origin.
US10174146B2	Dual cure acrylic formulations and methods to cure thereof In some embodiments, the present invention is a method, comprising: a) mixing at least one polymerizable acrylic compound, a thermal initiator, a photoinitiator, and a peroxide to form a mixture, wherein the peroxide has a decomposition temperature; b) exposing the mixture to light for a sufficient first time to generate a first curing agent; and c) after exposing the mixture to light, exposing the mixture to a temperature below the decomposition temperature of the peroxide for a sufficient second time to generate a second curing agent.
US10174144B2	Cationic copolymers The present invention relates to cationic copolymers, a process for the production of these cationic copolymers and the use of these cationic copolymers as dispersants for geopolymer binder systems. These cationic copolymers where the cationic charge is due to the presence of certain cyclic and/or polycationic groups are stable towards Hoffmann elimination that would otherwise occur at very high pH values. Moreover, the dispersing effect of cationic polymers can be further enhanced through the addition of polyvalent anions.
US10174140B2	Non-halogen flame retardant polymers Non-halogenated monomers that can be polymerized into flame retardant polymers, and processes to produce the monomers and polymers is provided. In a simplest aspect, there is provided a monomer composition that can comprise a) a group derived from one of a (meth)acrylic acid, (meth)acrylamide, or vinylbenzene, b) a polyphosphate moiety, and c) an amine species. In the monomer composition, the ethylenically unsaturated monomer of (a) is covalently bonded directly or through a linking group to the moiety of b), forming a precursor monomer unit. The amine species of c) is in complex with the precursor monomer unit. The polymer can be a homopolymer of the monomer composition, or a copolymer of the monomer composition having varying a), b) and c). In one embodiment, the polymer can additionally comprise ethylenically unsaturated monomers not covalently bonded to a polyphosphate moiety and/or can be cross-linked with a cross-linking agent such as resorcinol.
US10174139B2	Crosslinker-accelerator system for polyacrylates In the context of a polyacrylate-based composition, the intention is to allow controlled thermal crosslinking. This is accomplished by provision of a crosslinker-accelerator system for the thermal crosslinking of polyacrylates having functional groups suitable for entering into linking reactions with epoxide groups, comprising at least one substance comprising at least one epoxide group (crosslinker) and at least one substance conforming to the general formula (I) NR3 (I), in which the radicals R independently of one another are a hydrogen atom or an organic radical having 1 to 20 carbon atoms, with at least one of the radicals R being an organic radical with 1 to 20 carbon atoms, and comprising at least one alcoholic OH group.
US10174137B2	Butene-1 terpolymers and process for their preparation Butene-1 terpolymers having a content of propylene derived units of 0.5-13% mol, and a content of ethylene derived units of 1-3% mol, a ratio C3/C2 of the content of propylene and ethylene derived units is of from 1 to 10, said butene-1 terpolymers having a melt flow rate MIE, measured at 190° C./2.16 Kg of from 0.3 to 3 g/10 min, and a molecular weight distribution curve determined by GPC with a ratio Mw/Mn of from 4 to 10, and the portion of molecular weights of 1×105 or lower, accounting for 22% or larger of the total area.
US10174132B2	Heparan sulfate synthesis The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in numerous ways to produce a range of oligosaccharides.
US10174127B2	Human neutralizing antibodies binding to influenza neuraminidase The present invention provides influenza neuraminidase (NA)-binding human antibodies, which are capable of neutralizing at least one influenza A virus strain comprising NA of the N1 subtype, and antigen-binding fragments thereof. In certain embodiments, the antibodies or antigen-binding fragments furthermore are capable of neutralizing at least one influenza A virus strain comprising NA of the N2 subtype. The invention furthermore relates to the use of said antibodies or antigen-binding fragments in the diagnosis, prophylaxis and/or treatment of influenza infection.
US10174125B2	Conjugation reagents The invention provides compound of the general formula: in which each X independently represents a polymer chain; n represents an integer greater than 1; Q represents a linker; Y represents an amide group; and Z represents either —CH.(CH2L)2 or —C(CH2L)(═CH2), in which each L independently represents a leaving group. The compounds are useful reagents for the conjugation of polymers to proteins, the resulting conjugates being novel and also forming part of the invention.
US10174124B2	Anti-CD3 antibodies and methods of use The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
US10174123B2	Antibody and binding fragment recognizing CACNA2D1 and use thereof Disclosed is a method for searching, identifying, or validating a marker CACNA2D1 of tumor-initiating cells. The method comprises a step of immunizing an animal using HEP-12 cells originating from a recurrent tumor and rich in originating cells. Also disclosed is a monoclonal antibody specially recognizing CACNA2D1 or antigen-binding fragments thereof, and the use thereof for treating or preventing tumors or diseases or conditions related to CACNA2D1.
US10174121B2	Anti-CD40 antibodies The present invention encompasses antagonist anti-CD40 antibodies and antigen-binding portions thereof. Specifically, the invention relates to humanized anti-CD40 antibodies. In certain embodiments, antibodies of the invention neutralize human CD40 (hCD40) activity. Antibodies, or antibody portions, of the invention are useful for detecting CD40 and for inhibiting CD40 activity, e.g., in a human subject suffering from a disorder in which CD40 activity is detrimental.
US10174120B2	Methods and compositions for treating solid tumors and enhancing tumor vaccines The present invention provides methods of treating and enhancing efficacy of immunotherapy for a solid tumor in a subject, comprising the step of contacting the subject with a compound or composition that modulates the expression or activity of ETRB, ET-1, ICAM-1, or another protein found herein to play a role in homing of T cells to a solid tumor. The present invention also provides methods of prognosticating a solid tumor in a subject, comprising the step of measuring an expression level of a protein found herein to play a role in homing of T cells to a solid tumor, or a nucleotide molecule encoding same.
US10174118B2	Nucleic acids encoding chemokine receptor binding polypeptides The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2.
US10174112B2	Compound that specifically binds to KIR3DL2 for use in the treatment of peripheral T cell lymphoma The present invention relates to methods for the treatment, prevention and diagnosis of peripheral T cell lymphoma using compounds that specifically bind KIR3DL2. The invention also relates to use of antibodies that specifically bind KIR3DL2 in diagnostic and theranostic assays in the detection and treatment of peripheral T cell lymphoma.
US10174111B2	Therapeutic drug for malignant tumors According to the present disclosure there are provided compositions and methods for treating malignant tumors, including an anti-LSR (lipolysis stimulated lipoprotein receptor) antibody that comprises the presently disclosed antibody heavy and light chain complementarity determining region (CDR) sequences, or an antigen-binding fragment thereof, or a functional equivalent thereof. Further provided for treating an LSR-positive malignancy is an LSR antagonist or an LSR inhibitor such as a nucleic acid. Therapeutic administration of the anti-LSR antibody to a subject having an LSR-positive malignant tumor is also described.
US10174110B2	Highly galactosylated anti-TNF-α antibodies and uses thereof In one aspect, the disclosure relates to highly galactosylated anti-TNF-alpha antibodies and compositions thereof. In one aspect, the disclosure relates to populations of anti-TNF-alpha antibodies with a high level of galactosylation, and compositions thereof. In one aspect, the disclosure relates to methods of production and use of highly galactosylated anti-TNF-alpha antibodies and populations of anti-TNF-alpha antibodies with a high level of galactosylation. In some embodiments, the anti-TNF-alpha antibody is adalimumab.
US10174109B2	Method for producing human monoclonal antibodies that binds to at least one part of HMGB1 The present invention relates to methods of making human anti-HMGB1 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions in HMGB1 associated-neuropathy.
US10174108B2	Antibodies to TGF-beta The present invention relates to antibody molecules, in particular antibody molecules that bind. Transforming Growth Factor beta (TGFβ), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralize TGFβ1, TGFβ2 and TGFβ3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
US10174106B2	Anti-neurotensin long fragment antibodies and uses thereof The present invention relates to a neutralizing antibody which is capable of binding to neurotensin with high affinity. The antibody of the present invention neutralizes the activity of neurotensin, in particular the oncogenic activities of neurotensin. In particular, the present invention relates to a neutralizing antibody which binds to the human neurotensin long fragment, and having a heavy chain variable region which comprises a H-CDR1 region having at least 90% of identity with SEQ ID NO:2, a H-CDR2 region having at least 90% of identify with SEQ ID NO:3 and a H-CDR3 region having at least 90% of identity with SEQ ID NO:4; and a light chain variable region comprising a L-CDR1 region having at least 90% of identity with SEQ ID NO:6, a L-CDR2 having at least 90% of identity with SEQ ID NO:7 and a L-CDR3 region having at least 90% of identity with SEQ ID NO:8. The present invention also provides the use of such antibodies in the treatment of cancer.
US10174104B2	Monoclonal antibodies against claudin-18 for treatment of cancer The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
US10174103B2	Mycoplasma pneumoniae immunological detection method and kit [Problem]An object of the present invention is to provide a detection marker that can simply and rapidly detect Mycoplasma pneumoniae, which is a pathogen of mycoplasma pneumonia, at a high sensitivity, a specific antibody against the marker, and also an immunological detection method and a kit containing the antibody.[Solution]Infection with Mycoplasma pneumoniae can be rapidly and specifically diagnosed by producing an antibody specifically reactive to P30 protein of Mycoplasma pneumoniae and performing an immunological assay using the P30 protein as a detection marker. The present invention enables easy and rapid detection of Mycoplasma pneumoniae and diagnosis of infection with the bacteria at a hospital or the like without need of specialized instruments or skilled techniques.
US10174102B2	Antibody frameworks The present invention relates to novel antibody frameworks with advantageous properties. For example, this invention relates to novel chimeric human antibody light chain frameworks, comprising framework regions I to III from Vκ and framework region IV from Vλ, with advantageous properties, such as high stability and reduced aggregation propensity.
US10174097B2	Specific A-beta species-binding peptides for the therapy and/or diagnosis of Alzheimer's dementia The invention relates to peptides binding specifically to Abeta species for treating and/or diagnosing Alzheimer's disease.
US10174096B2	Feline bitter taste receptors and methods A family of novel feline bitter taste receptors, referred to as feline TAS2R (fTAS2R), are disclosed herein. Isolated polynucleotides encoding the novel feline bitter taste receptors and chimeric polypeptides are also disclosed, as are expression vectors and host cells for expression of the novel feline bitter taste receptors. Methods of identifying compounds that bind to the novel feline bitter taste receptors and modulate their activity are disclosed.
US10174095B2	Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor The invention provides compositions and methods for treating diseases associated with expression of BCMA. The invention also relates to chimeric antigen receptor (CAR) specific to BCMA vectors encoding the same, and recombinant T cells comprising the BCMA CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a BCMA binding domain.
US10174094B2	Reversible covalent linkage of functional molecules The present invention relates to the use of a compound containing a moiety of formula (I) as a reagent for linking a compound of formula R1—H which comprises a first functional moiety of formula F1 to a second functional moiety of formula F2 wherein X, X′, Y, R1, F1 and F2 are as defined herein. The present invention also provides related processes and products. The present invention is useful for creating functional conjugate compounds, and specifically conjugates in which at least one of the constituent molecules carries a thiol group.
US10174090B2	FGF21 protein with enhanced binding affinity for β-Klotho for the treatment of type II diabetes, obesity, and related metabolic disorders The present invention relates to chimeric proteins that include an N-terminus coupled to a C-terminus, where the N-terminus includes an N-terminal portion of fibroblast growth factor 21 (“FGF21”) and the C-terminus includes a C-terminal portion of fibroblast growth factor 19 (“FGF19”). The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, as well as methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, methods of treating a subject in need of increased FGF21-βKlotho-FGF receptor complex formation, methods of causing increased FGF21 receptor agonist-βKlotho-FGF receptor complex formation, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention.
US10174085B2	Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides delta toxin and phenol-soluble modulin peptides as well as mutants, fragments, variants or derivatives thereof. The disclosure further provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal proteins, e.g., DT, PSM, alpha hemolysin, leukocidin, superantigen, or any fragments, variants, derivatives, or mutants thereof fused together as a single polypeptide in any order.
US10174083B2	Aza-amino acid collagen compounds The invention relates to aza-amino acid backbone-modified biomimetic collagens and general methods for designing and making biomimetic materials and molecular mimics.
US10174082B2	Amylin and calcitonin receptor agonist The present invention relates to peptides comprising an amino acid sequence SEQ ID NO: 1 (EASELSTAALGRLSAELHELATLPRTETGPESP), analogs and derivatives thereof and pharmaceutical compositions comprising such peptides and derivatives. This invention further regards the use of these peptides according to SEQ ID NO: 1, analogs and derivatives thereof as medicaments.
US10174076B2	Protein purification process A method of purifying a target protein includes contacting a cell culture harvest or a protein preparation including at least one target protein with at least one fatty acid having 8 to 10 carbon atoms to form a mixture, contacting the mixture with one or more solids to form a mixture, the one or more solids comprise a cationic functional group, a metal binding functional group, or both, the metal binding functional group including a nitrogen-containing moiety selected from (1) a polyamine, (2) an imine, (3) an N-heterocycle, (4) an amino acid, (5) an N-hydroxyamide, (6), an arylamine, and combinations thereof, and separating solid materials after contacting the mixture with the one or more solids to provide a solution comprising the target protein.
US10174072B2	Antileishmanial compositions and methods of use In one aspect, the invention relates methods and compositions for treating parasitic diseases, for example, leishmaniasis. In a further aspect, the compounds of the methods and compositions are isolated from Pentalinon andrieuxii. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US10174071B2	Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof The present invention further provides method of preparing nanocrystals of a hydrophobic therapeutic agent such as fluticasone or triamcinolone, pharmaceutical compositions (e.g., topical or intranasal compositions) thereof and methods for treating and/or preventing the signs and/or symptoms of disorders such as blepharitis, meibomian gland dysfunction or skin inflammation or a respiratory disease (e.g., asthma).
US10174069B2	Virus detection The invention provides methods and materials for use in the detection of influenza viruses which utilise a nanoparticle, for example gold nanoparticle, probe comprising a plurality of glycoconjugate ligands, each glyconjugate ligand (GL) having a plurality of sialic-acid containing recognition group (Y) coupled to the nanoparticle via a multivalent core (X), wherein the multivalent core (X) is a trivalent core, whereby there are 3 recognition groups per ligand, wherein the recognition groups on the bioconjugate specifically bind to the hemagglutinin on the target influenza virus. The probes may include further ligands bound to the nanoparticle which do not bind specifically to an influenza virus—for example polyethylene glycol groups. These can modulate density of the glycoconjugate ligand on the surface of the nanoparticle. Binding of probes is detected by a plasmonic signal which is specific to the influenza virus.
US10174066B2	Methods and compositions for incorporating nucleotides The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
US10174065B2	Antidiabetic enolic glucoside of phenylpyruvic acid There is provided an antidiabetic enolic glucoside of phenylpyruvic acid and derivatives thereof for use as medicaments, especially normoglycemic agents, i.e. for lowering blood glucose levels to normal levels in mammals that are obese, pre-diabetic or have diabetes, obesity and/or syndrome X. Hence the compounds of the present invention help to manage blood sugar levels, i.e. helping the body by balancing the blood sugar levels; helping to keep balanced blood glucose levels, particularly in humans with diabetes; aiding by enhancing the glucose uptake by the cells and by reducing sugar levels, thus improving or restoring the glucose tolerance; optimizing the glycemic response; normalizing the glucose tolerance.
US10174058B2	Vinyl silane compound Provided is a compound for imparting a thermal plasticity to an organic silicon resin. The compound is a novel vinyl silane compound represented by the following formula (1): wherein A independently represents a divalent hydrocarbon group having 1 to 6 carbon atoms; Y independently represents a substituted or unsubstituted monovalent hydrocarbon group having 1 to 12 carbon atoms.
US10174056B2	Substituted pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors A compound having the structure of below Formula(I), or pharmaceutically acceptable salts thereof, are useful as Janus kinase inhibitors, wherein R1 and L1 are as herein described.
US10174055B2	Synthetic method of fused heteroaromatic compound and fused heteroaromatic compound and intermediate therefor A synthetic method of a fused heteroaromatic compound includes preparing a first intermediate represented by Chemical Formula 1, obtaining a second intermediate by reacting the first intermediate and an aldehyde compound, obtain a third intermediate by performing deprotection and reduction reactions on the second intermediate, and obtaining a fused heteroaromatic compound by performing a cyclization reaction on the third intermediate.
US10174054B2	Compounds and methods for the treatment of Alzheimer's disease and/or cerebral amyloid angiopathy Described herein are novel compounds and methods for the treatment and/or prevention of cerebral amyloidoses such as Alzheimer's disease (AD) and/or cerebral amyloid angiopathy (CAA).
US10174050B2	Spiroisoxazoline compounds having an activity potentiating the activity of an antibiotic The present invention concerns a spiroisoxazoline compound of general formula (I): in which m and n are 0 or 1, R1 represents, inter alia, an optionally substituted alkyl chain, in particular substituted with fluorine or with a cyclic group, and R2 is chosen from phenyl and optionally substituted benzyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, and the heterocycles having 5 or 6 vertices comprising at least one atom chosen from S, N and O. The present invention also concerns the use of this compound as a drug, in particular in the treatment of bacterial and mycobacterial infections such as tuberculosis in combination with an antibiotic that is active against bacteria and/or mycobacteria, said compound potentiating the activity of said antibiotic.
US10174044B2	Fused pyridines as kinase inhibitors The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
US10174041B2	Methods and compositions for inhibiting the interaction of menin with MLL proteins The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin.
US10174040B2	Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof A pyrrolopyrimidine compound or a salt thereof and compositions, NAE inhibitors and anti-tumor agents containing the pyrrolopyrimidine compound or a salt thereof. The pyrrolopyrimidine compound or a salt thereof has an NAE inhibitory action and a cell growth inhibitory effect and is represented by Formula (A):
US10174039B2	P2X3 and/or P2X2/3 compounds and methods The present disclosure provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R7 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.
US10174037B2	Dihydropyrazolopyrimidinone compounds as PDE2 inhibitors The present invention is directed to dihydropyrazolopyrimidinone compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
US10174035B2	6-morpholinyl-2-pyrazolyl-9H-purine derivatives and their use as PI3K inhibitors The present invention relates to a pyrazole derivative of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, stereoisomer thereof or a deuterium form thereof, wherein, n, Y, Ra, R1, R2, R3, R4, R5 and R6 are as defined hereinafter in the specification, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) as inhibitors of phosphatidylinositol-3-kinase (PI3K), which can be used for treating or preventing inflammatory, autoimmune, orphan and hyperproliferative disease and disorder.
US10174024B2	5H-pyrido[3,2-B]indole compounds as anticancer agents The present invention is directed to tricyclic compounds of formula (I), pharmaceutically acceptable compositions comprising compounds of the invention and said compositions for use in methods for the treatment of various disorders in particular cancer.
US10174023B2	Heterocyclic-imidazole compounds, pharmaceutical compositions thereof, preparation method therefor and use thereof The present invention relates to heterocyclic-imidazole derivatives, a preparation method therefor, and a medical use thereof, and particularly to new heterocyclic-imidazole derivatives as represented by general formula (I), a preparation method therefor, pharmaceutical compositions comprising same, and a use thereof as a therapeutic agent, particularly as a poly(ADP-ribose)polymerase (PARP) inhibitor.
US10174018B2	Protein kinase inhibitors The present invention is directed to novel protein kinase inhibitors comprising the chemical compound N-(2-chloro-6-methylphenyl)-2-[[2-methyl-6-(3-hydroxypyrrolidin-1-yl)pyrimidin-4-yl]amino]thiazole-5-carboxamide, its pharmaceutically acceptable salts, enantiomers, and enantiomeric mixtures, and methods of use to treat protein kinase-mediated diseases or conditions.
US10174013B2	Benzimidazole derivatives as kinase inhibitors The present invention relates to derivatives of benzimidazoles of formula (I) as disclosed herein as well as pharmaceutical compositions comprising said derivatives. The derivates according to the present invention are serine/threonine and tyrosine kinase-inhibitors, particularly of PIM1-3- and DYRK1A-kinases and may particularly be used in the treatment of diseases linked to these kinases, such as e.g. leukemias, lymphomas, solid tumors and autoimmune disorders.
US10174012B2	LKB1-AMPK activators for therapeutic use in polycystic kidney disease Compounds are provided for use in treating polycystic kidney disease (PKD) and in associated methods that include a method of modulating (e.g., activating) Liver kinase B1 (LKBI); and a method of modulating (e.g., decreasing activity) mammalian target of rapamycin (mTOR). The methods may include introducing the compound in a therapeutically effective amount to a subject having PKD. The methods may include introducing the compound in a therapeutically effective amount to a subject having Autosomal Dominant PKD. The compounds can be used in methods of treating a disease modulated by a mTOR pathway, which can include introducing the compound in a therapeutically effective amount to a subject having the disease modulated by the mTOR pathway. The disease modulated by mTOR is selected from the group consisting of multiple types of cancer, leukemia, kidney disease, obesity, neuro disorders and alcohol-related chronic diseases.
US10174011B2	Heterocyclic compounds, process for preparation of the same and use thereof The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.
US10174010B2	Canagliflozin monohydrate and its crystalline forms, preparation methods and uses thereof The present invention relates to canagliflozin Monohydrate and its crystalline forms, which as compared to the prior art, have higher stability in water or aqueous system, are more suitable for wet granulation processes or suspension preparations and have good storage stability; the present invention also relates to preparation methods of canagliflozin Monohydrate and its crystalline forms, pharmaceutical compositions thereof and uses thereof in preparation of drugs for treating diseases such as diabetes, diabetes complications, obesity and so on.
US10174007B2	Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors Provided herein are substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
US10174003B2	Histone demethylase inhibitors The present invention relates generally to compositions and methods for treating cancer and neoplastic diseases. Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase enzymes. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as pancreatic cancer, prostate cancer, breast cancer, bladder cancer, lung cancer, gastric cancer, leukemia and/or melanoma and the like.
US10174002B2	Pyridine derivatives as CFTR modulators A compound having the structure of Formula II, or a stereoisomer, tautomer, or a pharmaceutically acceptable salt thereofthat is useful as CFTR modulator. Further, a method of using the compound and pharmaceutical composition comprising the compound are provided for treating diseases in lungs, pancreas, gastrointestinal system, sinuses, reproductive system, and the sweat glands.
US10173996B2	Histone demethylase inhibitors Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
US10173995B2	Pyridine compounds used as PI3 kinase inhibitors The present invention is directed to novel pyridines, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The present invention discloses compounds of Formulas I and II. The compounds and compositions of the present invention have protein kinases inhibitory activities and are expected to be useful for the treatment of protein kinases mediated diseases and conditions.
US10173994B2	Conversion of biomass Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert feedstock materials to a sugar solution, especially, xylose, which can then be chemically converted to furfural and furfural-derived products.
US10173992B2	Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound A polymerizable compound has a practical low melting point, excellent solubility in a general-purpose solvent, and can produce an optical film at low cost, exhibits low reflected luminance, and achieves uniform conversion of polarized light over a wide wavelength band, an optically anisotropic article. A carbonyl compound is useful as a raw material for producing the polymerizable compound. (In the formula (I), Y1 to Y8 represent —C(═O)—O—, G1 and G2 represent a C1-20 divalent linear aliphatic group, Z1 and Z2 represent a C2-10 alkenyl group that is unsubstituted, or substituted with a halogen atom, Ax represents a C2-30 organic group with at least one aromatic ring, Ay represents a hydrogen atom or C1-20 alkyl group, A1 represents a trivalent aromatic group, A2 and A3 represent a C3-30 divalent alicyclic hydrocarbon group, A4 and A5 represent a C6-30 divalent aromatic group or the like, and Q1 represents a hydrogen atom.)
US10173990B2	URAT1 inhibitor Provided are a compound represented by the following Formula (III), a tautomer or stereoisomer of the compound, or a pharmaceutically acceptable salt or solvate thereof used as a therapeutic agent for gout or hyperuricemia. (In the Formula (III), R1a, R2a, R6a, and R7a represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, or a cyano group, R3a and R8a form a benzene ring or a 5-membered heteroaryl ring containing 1 to 3 heteroatoms, as a ring constituent element, selected from nitrogen atoms, oxygen atoms, and sulfur atoms together with two carbon atoms to which R3a and R8a are bonded, R4a and R5a form a benzene ring together with two carbon atoms to which R4a and R5a are bonded or represent any of the groups represented by R1a described above, Wa represents CR10a or N, and where, R10a represents any of the groups represented by R1a, Xa represents an oxygen atom or a sulfur atom, Ya represents an alkylene chain having 1 to 8 carbon atoms, and where, the alkylene chain may be substituted with an alkyl group having 1 to 8 carbon atoms and the alkylene chain may be a linear or branched alkylene chain, the branched alkylene chain may have a 3- to 7-membered ring formed by side chains bonded to carbon atoms which are the same as or different from each other, together with the carbon atoms to which the side chains are bonded and may have a double bond in the middle thereof, and Za represents CO2H).
US10173988B2	N2-(3,4-dimethylphenyl)-6-((4-(p-tolyl)piperazin-1-yl)methyl)-1,3,5-triazine-2,4-diamine The compound N2-(3,4-dimethylphenyl)-6-((4-(p-tolyl)piperazin-1-yl)methyl)-1,3,5-triazine-2,4-diamine or a pharmaceutically acceptable salt of said compound. The compound is useful the treatment of a condition or disorder associated with nicotinamide adenine dinucleotide phosphate oxidase activity. A pharmaceutical composition comprising the compound.
US10173987B2	Hydrazide containing nuclear transport modulators and uses thereof The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
US10173985B2	Aminoindazole derivatives as sodium channel inhibitors The present invention relates to novel aminoindazolyl derivative compounds of Formula (I), the use of said compounds in treating diseases mediated by modulation of voltage-gated sodium channels in particular Nav 1.7, to compositions containing said derivatives and processes for their preparation.
US10173978B2	Small molecule androgen receptor inhibitors and methods of use thereof Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein. Also provided herein are methods for using the carbazole compounds in treating prostate cancer, including castration-resistant prostate cancer and enzalutamide-resistant prostate cancer. The methods include administering to a subject an effective amount of a compound or composition as described herein.
US10173977B2	5-aryl-1H-pyrrole-3-carbonitrile and a pharmaceutical product using the same The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.
US10173976B2	Aziridinyl containing compounds and methods of inactivating nucleic acid molecules using the same Described herein are compositions and compounds having one or more aziridinyl groups, and methods of making the same. The compounds can also have one or more nitrogen atoms that each can be positively charged. The composition and compounds can inactivate one or more nucleic acid molecules (e.g. a DNA and/or a RNA from a pathogen) in a sample. The sample can comprise a blood or blood product (e.g., donated blood). The compositions and compounds can inactivate any nucleic acid present in a blood or blood product, thereby making the blood or blood product safe for use (e.g., in a transfusion).
US10173973B2	Alkylidene aminoguanidine and salt thereof, modifying composition, modified rubber for tire, rubber composition for tire, and tire Provided is a compound represented by formula (1): wherein X is an acid to form a salt with a guanidine site; and R1 and R2 are each independently any selected from the group consisting of a hydrogen atom, a C1-18 alkyl group, a cycloalkyl group, an aryl group, an alkylaryl group, and an alkenyl group, each of the groups optionally having one or more substituents each containing a sulfur atom, a nitrogen atom, or an oxygen atom.
US10173971B2	Picolinamides with fungicidal activity The invention relates to picolinamides of Formula I and their use as fungicides.
US10173968B2	Bishydrazone-based antifungal agents Hydrazone compounds and pharmaceutical compositions including same are disclosed as having antifungal activity. Such compounds are useful for treating or preventing fungal conditions in a subject in need thereof by administering same.
US10173965B2	Method for preparing pregabalin intermediate 3-carbamoymethyl-5-methylhexanoic acid without solvent The present invention provides a method for preparing a pregabalin intermediate 3-carbamoymethyl-5-methylhexanoic acid without solvent. The method comprises the following steps: a) cooling an ammonia water system to a certain temperature; b) adding 3-isobutylglutaric anhydride dropwise to the system, then keeping temperature, and reacting; c) after completing the reaction, adding an acid to the system to adjust pH; d) after adjusting pH, cooling, then keeping temperature, crystallizing, then suction filtering and drying; and e) adding a solvent to the dried substance, slurrying, and suction filtering and drying to obtain the final product. The method provided in the present invention for preparing 3-carbamoymethyl-5-methylhexanoic acid is high-yield, green, environmentally-friendly, simple and convenient, and of less pollution.
US10173962B2	Method for producing trans-rich-1,4-bis(aminomethyl)cyclohexane The method for producing trans-rich-1,4-bis(aminomethyl)cyclohexane includes blending 1,4-bis(aminomethyl)cyclohexane with an alkali metal compound and XDA and heating the mixture to isomerize 1,4-bis(aminomethyl)cyclohexane so that the trans isomer content relative to the cis/trans isomers in total is more than 70 mass %, and purifying the isomerized 1,4-bis(aminomethyl)cyclohexane by distillation after the isomerization step. The alkali metal compound is at least one compound selected from the group consisting of alkali metal hydride, alkali metal amide, and alkyl alkali metal. In the isomerization step, 0.01 mol or more and less than 4 mol of XDA is blended relative to 100 mol of 1,4-bis(aminomethyl)cyclohexane, a dimer produced from one molecular of 1,4-bis(aminomethyl)cyclohexane and one molecular of XDA, and a trimer produced from two molecules of 1,4-bis(aminomethyl)cyclohexane and one molecular of XDA are produced, and the dimer content is 5 mass % or more and less than 75 mass % relative to the dimer and trimer in total.
US10173958B2	Method for producing multibranched aliphatic ester A method for producing a multibranched aliphatic ester including reacting a multibranched aliphatic alcohol with a multibranched aliphatic carboxylic acid in the absence of a solvent without a catalyst to obtain a multibranched aliphatic ester, and distilling the multibranched aliphatic ester to obtain a purified multibranched aliphatic ester, wherein at least one of the alcohol and the carboxylic acid is a C10-30 compound, and the obtained ester has a Hazen color number (APHA) of 1 to 30. Each of the multibranched aliphatic alcohol and the multibranched carboxylic acid has a tertiary carbon atom and/or a quaternary carbon atom in the molecule and in which the total number of the tertiary carbon atom and/or the quaternary carbon atom in the molecule is 2 or more. The method wherein the reaction is caused at 180 to 300° C. The method wherein a monohydric alcohol and a monovalent carboxylic acid are used.
US10173953B2	Method and device for producing L-menthol in solid form A process for producing L-menthol in solid form, including the following steps: providing a menthol melt, feeding the melt to a drop former having a rotating, perforated outer drum and a fixed nozzle strip adjacent to the inside of the outer drum, depositing the menthol melt produced by the drop former onto a continuous cooling belt, solidifying the menthol melt during transport on the cooling belt to form L-menthol pellets and taking the pellets off in the region of a deflection drum for the cooling belt.
US10173950B2	Integrated process for the production of benzene and xylenes from heavy aromatics Systems and processes for maximizing the production of benzene and para-xylene from heavy reformate are provided. An integrated process and system may include a C9 dealkylation reactor, a transalkylation reactor, and a C10+ dealkylation reactor. The integrated process and system for producing benzene and para-xylene may be configured to additionally produce alkanes in the presence of hydrogen or olefins in the absence of hydrogen. The transalkylation reactor may perform transalkylation of product from the C9 dealkylation reactor and xylene isomerization.
US10173946B2	Apparatus and process for producing gasoline, olefins and aromatics from oxygenates Apparatuses and processes for converting an oxygenate feedstock, such as methanol and/or dimethyl ether, in a fluidized bed containing a catalyst to hydrocarbons, such as gasoline boiling components, olefins and aromatics are provided herein.
US10173944B2	Compositions usable as flare compositions, countermeasure devices containing the flare compositions, and related methods A composition that includes a fuel and a perfluoropolyether (PFPE) is disclosed. The composition may be used as a flare composition in a countermeasure device. Countermeasure devices including the flare composition are also disclosed, as are methods of forming grains of the countermeasure device.
US10173936B2	Processes for producing fuels and biofertilizers from biomass and products produced An IBTL system having a low GHG footprint for converting biomass to liquid fuels in which a biomass feed is converted to liquids by direct liquefaction and the liquids are upgraded to produce premium fuels. Biomass residues from the direct liquefaction, and optionally additional biomass is pyrolyzed using microwave pyrolysis to produce structured biochar, hydrogen for the liquefaction and upgrading, and CO2 for conversion to algae, including blue green algae (cyanobacteria) in a photobioreactor (PBR). Produced algae and diazotrophic microorganisms are used to produce a biofertilizer that also contains structured biochar. The structured biochar acts as a nucleation agent for the algae in the PBR, as a absorption agent to absorb inorganics from the biomass feed to direct liquefaction or from the liquids produced thereby, and as a water retention agent in the biofertilizer. The ratio of cyanobacteria to diazotrophic microorganisms in the biofertilizer can be selected so as to achieve desired total chemically active carbon and nitrogen contents in the soil for a given crop.
US10173929B2	Sintering material, and powder for manufacturing sintering material The present invention is a sintering material including a granule, the sintering material having an apparent tap density of 1.0 to 2.5 g/cm3, a 50% cumulative volume particle diameter (D50N) of 10 to 100 μm as measured before ultrasonication by laser diffraction/scattering particle size distribution analysis, a 50% cumulative volume particle diameter (D50D) of 0.1 to 1.5 μm as measured after ultrasonication at 300 W for 15 minutes by laser diffraction/scattering particle size distribution analysis, and an X-ray diffraction pattern in which the maximum peak observed in the 2θ angle range of from 20° to 40° is assigned to a rare earth oxyfluoride of the form LnOF when analyzed by X-ray diffractometry using Cu—Kα or Cu—Kα1 rays.
US10173928B2	Dielectric ceramic composition A dielectric ceramic composition includes a first inorganic component having a trigonal ditrigonal pyramidal crystal structure, a second inorganic component having a hexoctahedral crystal structure, and a solid solution portion of the trigonal ditrigonal pyramidal crystal structure and the hexoctahedral crystal structure is formed between the first inorganic component and the second inorganic component.
US10173927B2	Carbonatable calcium silicate compositions and methods thereof The invention provides novel carbonatable calcium silicate compositions and carbonatable calcium silicate phases that are made from widely available, low cost raw materials by a process suitable for large-scale production. The method of the invention is flexible in equipment and production requirements and is readily adaptable to manufacturing facilities of conventional cement. The invention offers an exceptional capability to permanently and safely sequesters CO2.
US10173926B2	Calcium sulfo aluminate cement with polymer A calcium sulfoaluminate-based concrete with a permeability of less than 1000 Coulombs. Rapid-setting low chloride-ion permeability calcium sulfoaluminate (CSA) cements and concretes include CSA and a suitable polymer such as a sol-gel derived, organic-inorganic, silica based hybrid coating solutions of polystyrene-butylacrylate polymers containing active silanol groups protected by hydroxyl groups containing polyalcohol, or other polymers. Such polymers may be added as powders or as liquid in the finish mill. Other rapid-setting low chloride-ion permeability (CSA) cements and concretes include CSA with selected particle size distributions, and do not require use of any polymer. These CSA cements and concretes have low chloride-ion permeability, high early strength, fast setting times, low-shrinkage, and high freeze-thaw resistance.
US10173923B2	Tempered glass, tempered glass plate, and glass for tempering A tempered glass has a compressive stress layer in a surface thereof, includes as a glass composition, in terms of mass %, 50 to 80% of SiO2, 10 to 30% of Al2O3, 0 to 6% of B2O3, 0 to 2% of Li2O, and 5 to 25% of Na2O, and is substantially free of As2O3, Sb2O3, PbO, and F.
US10173917B2	Method for producing granules and method for producing glass product To provide granules for the production of silicate glass, said granules being less likely to adhere even if heated at a high temperature exceeding 800° C. A method for producing granules, which has a step of mixing a glass raw material composition composed essentially of an alkali metal source, an alkaline earth metal source and a powdery silicon source, with water, followed by compression molding, and which is characterized in that the glass raw material composition contains at least 50 mass % of the silicon source, and at least 10 mass % in total of the alkali metal source and the alkaline earth metal source, as calculated as oxides, based on 100 mass % of the silicate glass obtainable from the granules, the alkali metal source contains an alkali metal carbonate, and D90 representing the particle size at a cumulative volume of 90% in the particle size accumulation curve of the alkaline earth metal source is at most 100 μm.
US10173909B2	Tubular fluid purification apparatus A tubular fluid purification apparatus includes a guide part provided with an inlet port into which fluid is drawn, a discharge part provided with an outlet port from which the fluid is discharged, a conduit part configured to provide a space for flow of the fluid between the guide part and the discharge part, and a purification of unit supported on an inner surface of the conduit part and disposed to face the fluid flowing from the guide part to the discharge part. The purification unit includes a vortex generation part including a support and an opening formed in the support, and a light emitting diode disposed on the support at a position adjacent to the opening and configured to provide ultraviolet light.
US10173907B2	Recyclable porous desalination material A porous material including polymerized units containing pores is provided, which can be employed for desalination applications. Each of the units includes at least one aromatic amino group and at least one hydroxyl group. The aromatic amino groups and the hydroxyl groups are arranged on surfaces of the pores in geometries configured to capture sodium chloride from an aqueous environment. The porous material can be provided as particles or a sponge. The porous material can be manufactured from a solution including monomers, a porogen, and an initiator by a polymerization process. The porous material can be reused after a desalination process by treatment with deionized water. A steam generation apparatus can be employed to facilitate removal of sodium chloride from the porous material in which sodium chloride is captured.
US10173896B2	Olivine composition with improved cell performance An olivine cathode material having the formula LiaFe1−x−y−zMnxD(y+z)(PO4)c, wherein a, c, x, y and z represent molar amounts, wherein D=Mg and/or Cr, wherein y represent the amount of Mg and z represents the amount of Cr, wherein 1.04
US10173895B2	Process for producing ammonia synthesis gas with high temperature shift and low steam-to-carbon ratio A process for producing ammonia synthesis gas from a hydrocarbon-containing feedstock in a front-end, comprising the steps of steam reforming of said feedstock, obtaining a synthesis gas comprising hydrogen, carbon monoxide and carbon dioxide; a treatment of said synthesis gas including shift of carbon monoxide and subsequent removal of carbon dioxide, wherein the shift of the synthesis gas includes high-temperature shift with an iron-based catalyst and at a temperature greater than 300° C. and the global steam-to-carbon ratio of the front end is 2.6 or less; a corresponding plant and a method for revamping a front-end of an ammonia plant are also disclosed.
US10173892B2	Integrated MEMS transducer and circuitry This application relates to an integrated circuit die (200) comprising a MEMS transducer structure (101) integrated with associated electronic circuitry (102). The electronic circuitry comprises a plurality of transistors and associated interconnections and is formed in a first area (103) of the die from a first plurality (104) of layers, e.g. formed by CMOS metal (107) and dielectric (108) layers and possibly doped areas (106) of substrate (105). The MEMS transducer structure is formed in a second area (111) of the die and is formed, at least partly, from a second plurality (112) of layers which are separate to the first plurality of layers. At least one filter circuit (201) is formed from said second plurality of layers overlying the plurality of transistors of the electronic circuitry (102). The second plurality of layers comprise at least a first metal layer (115, 117) which is patterned to form a first electrode of the MEMS transducer and at least a resistor, capacitor electrode or inductor element (203a, 203b) of the filter circuit.
US10173890B2	Microelectronic device housing bearing on the microelectronic device A box for a microelectronic device includes a first portion and a second portion able to be assembled in order to define, in an assembled position, a housing space for the microelectronic device. A face of the first portion is facing a face of the second portion in the assembled position. The first zones facing the faces form an interface for attaching the first portion and second portion. The second zones face faces forming a cavity for receiving the microelectronic device. At least one among the first portion and the second portion includes at least one element for electrical connection. The first portion and the second portion can apply at least one connection pad of the microelectronic device on the element for connection in the assembled position.
US10173888B2	Small wafer area MEMs switch Deep via technology is used to construct an integrated silicon cantilever and cavity oriented in a vertical plane which creates an electrostatically-switched MEMS switch in a small wafer area. Another embodiment is a small wafer area electrostatically-switched, vertical-cantilever MEMS switch wherein the switch cavity is etched within a volume defined by walls grown internally within a silicon substrate using through vias.
US10173883B2	Connector, socket, and liquid storing container Provided is a connector including a plug to be fixed to an inner peripheral surface of an opening of a liquid storing container, and a socket to be detachably attached to the plug. The plug includes a plug body including, formed therein, a first liquid outflow passage, a first liquid inflow passage, and a first gas passage. The socket includes: a socket body including, formed therein, a second liquid outflow passage, a second liquid inflow passage, and a second gas passage; and a ball lock mechanism that allows lock balls to be engaged with engagement grooves formed along a circumferential direction about an axial line in an outer peripheral surface of the opening of the liquid storing container and fixes the lock balls to the engagement grooves.
US10173877B2	Bottle cap opener There is provided a bottle cap opener comprising: a cylindrical body including an upper cylindrical body and a lower cylindrical body; an elongate screw bar passing through the upper cylindrical body at a center thereof, and passing beyond the upper cylindrical body upwards; a handle coupled to the elongate screw bar at a top end thereof; a screw protrusion coupled to the elongate screw bar at a bottom end thereof; both wings pivotally coupled to the upper cylindrical body at both-side pivotal portions thereof via both-side pivotal shafts respectively; and a silicon-based cap gripper formed on an inner face of the lower cylindrical body so as to grip a bottle cap tightly therein.
US10173876B2	De-centralized operational indicator system for a materials handling vehicle A materials handling vehicle comprises an operator compartment, forks that can be raised and lowered to carry a load, a power unit, an outward facing output module, and a controller. The outward facing output module comprises an indicator directed away from an operators' compartment of the materials handling vehicle. In operation, the controller receives information from at least one of a remote server, and electronics of the materials handling vehicle, via a materials handling vehicle network bus, where the received information is in regard to a task being performed by the materials handling vehicle. Also, the controller, responsive to detecting the task being performed, operates the indicator of the outward facing output module to provide situational awareness information with regard to the task.
US10173874B2	Integrated rack lifting apparatus A rack-mounted information handling system (IHS) includes a rack to mount functional compute components between opposing lateral sides that are being supported by floor supports. A pair of rack lifting structures are each respectively positioned beside a different opposing lateral side of the rack. Each rack lifting structure includes a foot having at least front and rear floor contacting portions. A vertical support includes a lower portion that is coupled to the foot and an upper portion that extends above an adjacent top lateral frame member of the rack. A top member is coupled to the vertical support and presents front and rear attachment components to engage the adjacent top lateral frame member. A jack engagement surface is defined within the vertical support to receive one or more furniture jacks that can be used to lift the pair of rack lifting structures and the attached rack-mounted IHS.
US10173862B2	Method for operating an elevator control device including sending an authorization code A process for operating an elevator control device, whereby for local access to the elevator control device via a programming device, the elevator control device automatically sends an identifier to the programming device and the identifier is input to an operator panel associated with the elevator control device. The elevator control device permits the local access when the previously sent identifier has been entered correctly within a predetermined input time.
US10173861B2	Handwriting input for elevator destination floor input A method includes receiving, by a computing device including a processor, a handwriting input including a selection of a destination floor associated with an elevator system, determining, by the computing device, that the handwriting input selection is recognizable, presenting, by the computing device, a message that requests confirmation that the input selection is interpreted correctly based on determining that the handwriting input selection is recognizable, receiving, by the computing device, a response to the message that confirms the input selection, and causing, by the computing device, the elevator system to provide access to the destination floor based on the response.
US10173858B2	Adhesive tape dispenser for folded edge tape An adhesive tape dispenser and applicator which folds one or both edges of tape being applied over upon themselves. The dispenser includes an edge folding guide having a planar surface, two inwardly converging edges and tape guides cooperating to fold the edges of the tape. A compression roller is provided to press the edges together. A method of threading tape onto an edge folding tape dispenser is also described.
US10173857B2	Sheet processing system and control method A sheet processing system according to an embodiment includes a tray that supports a sheet on opposite sides of the sheet orthogonal to a conveyance direction of the sheet. The tray includes a first adjustable support and second adjustable support positioned opposite the first adjustable support in the direction orthogonal to the conveyance direction of the sheet. A skew sensor detects a skew angle of the sheet conveyed to the tray. A corner sensor detects positions of each corner on a front end in the downstream direction of the sheet conveyed to the tray. A controller controls movement of the first and second adjustable supports based on the detected skew angle and the detected positions of each corner on the front end of the sheet conveyed to the tray so that the sheet is conveyed to the tray without jamming.
US10173853B2	Sheet feeding apparatus and image forming apparatus A feeding apparatus includes a sheet supporting member, a feeding member, and a lift unit. The lift unit lifts and lowers the sheet supporting member to abut a sheet stacked on the sheet supporting member against the feeding member. The lift unit includes an urging member that biases the sheet supporting member towards the feeding member, a moving member that moves in a first direction different from a sheet supporting member lifting direction, and a contact member in contact with the moving member. The contact member includes a curved cam surface in a region that comes in contact with the moving member. A contact state between the moving member and the contact member is changed by moving the moving member in the first direction and the curved cam surface. Regarding changing the contact state, the sheet supporting member can be moved to a feed position and a retracted position.
US10173850B2	Sheet feeding device and image forming apparatus A sheet feeding device for feeding a sheet includes a support unit, an open-close member rotatably supported between open and closed positions, a slide member supported in a slidably movable manner and including a rotation shaft portion, and a regulation member supported by the slide member. The open-close member supports the sheet in the open position with the support unit. The regulation member regulates a position of the sheet supported by the support unit or the sheet supported by the support unit and the open-close member. The support unit includes a guide portion that movably guides the rotation shaft portion. If the open-close member is rotated from the open position toward the closed position in a state in which the open-close member is in contact with the slide member, the slide member rotates by following movement of the open-close member with respect to the guide member.
US10173847B2	System for overturning plate-shaped bodies A system for overturning plate-shaped bodies, in particular slabs and sheets, having at least one overturn arm pivotally arranged about a pivot axis and can be brought into physical contact with a flat side of a plate-shaped body to be overturned, and at least one other overturn arm pivotally arranged about another pivot axis and can be brought into physical contact with another flat side of the plate-shaped body to be overturned. The two pivot axes are parallel to each other and mutually spaced. A permanent system is provided for overturning plate-shaped bodies with different dimensions, wherein noise generation associated with the overturning process is greatly reduced using the system. The system has at least one drivable eccentric arrangement with which a position of one of the pivot axes can be adjusted before and/or during an overturning process.
US10173845B2	Apparatus and methods for dispensing pre-filled containers with precisely-applied patient-specific information Apparatus and methods for fulfillment of patient prescription orders by adapting a standard or stock container pre-filled with medication or the like for use as a patient-specific container through precise application of patient-specific information to the pre-filled container. Precise placement of the patient-specific information to the pre-filled container enables pharmacy management to fully utilize valuable information provided with the pre-filled container, thereby improving the quality of service to the patient while making the process of prescription order fulfillment more efficient. In general, preferred embodiments comprise control apparatus and information-application apparatus. In embodiments, the information-application apparatus is adapted to place a patient-specific label on the container. Preferred forms of the information-application apparatus include a label printer and a positioner. The preferred printer applies patient-specific information on a label. The preferred positioner orients the pre-filled container to receive the label from the printer such that information provided with the container is available for use.
US10173843B2	Conveying arrangement for testing system An arrangement for conveying an electronic device in a testing system includes a conveyor arrangement, a plate having at least one opening for the conveyor arrangement, and an elevator configured to elevate the conveyor arrangement through the at least one opening of the plate. The conveyor arrangement is configured to receive and convey the electronic device when the conveyor arrangement extends through the at least one opening. The elevator is further configured to lower the conveyor arrangement through the at least one opening of the plate. The plate is configured to receive the electronic device from the conveyor arrangement in response to lowering the conveyor arrangement through the at least one opening. The plate is further configured to move with respect to the conveyor arrangement, and to carry the electronic device to a testing area of the testing system.
US10173839B2	Rack storage system and method for operating it The invention relates to a rack storage system comprising storage racks (12a, 12b) for load (2) and a load manipulation unit (4), which has at least a first load-lifting device (34a) with a transport device (36a) and a first buffer device (35a) with transport conveying devices (43, 44) and a rack aisle (15) and guide tracks (20) extending in the rack levels in the longitudinal direction of the rack aisle (15) and single-level rack serving devices (3) for transporting load (2) as well as a conveying system being connected to the load-lifting device (34a) for transporting load (2) to and from the load-lifting device (34a). The transport conveying devices (43) each form a removing path for the load (2) and the transport conveying devices (44) each form a storing path for the load (2). In a conveying section adjacent to the load-lifting device (34a), at least one of the conveying devices (106, 107) of the conveying system also comprises a transport conveying device (108; 110) for temporarily storing one or more pieces of load (2), the transport conveying device can be approached by the conveyor vehicle (3) via guide tracks (20′) to retrieve or store load (2).
US10173838B2	Load-receiving device Load-receiving device (1) for storing a cuboidal load (2) in a rack and for retrieving it therefrom, comprising two extendable telescopic arms (3, 4) which are spaced apart in parallel and on which there are arranged drivers (30, 40, 31, 41, 32, 42) situated opposite one another in pairs, which drivers can be pivoted into a swung-up position and into a position projecting at a right angle thereto, wherein the distance (d) between the telescopic arms (3, 4) is fixed or can be set in dependence on the width of the load. There is provision that each of the drivers (30, 40) situated opposite one another in pairs can be pivoted independently of the respective opposite driver, and/or that at least one of the drivers (30, 40) can be pivoted into at least one oblique intermediate position, that at least two mutually opposite edge detectors (300, 400, 302, 402) are arranged on the telescopic arms (3, 4) and are assigned to two mutually opposite drivers (30, 40, 32, 42), and that the drivers (30, 40) can be pivoted independently of one another in dependence on the output signal from the edge detectors (300, 400, 302, 402).
US10173831B2	Hinged lid packaging A blank for forming an inner packaging container of a pack for consumer goods including an outer packaging container and the inner packaging container. The inner packaging container includes a dispensing opening with a resealable closure, a front panel, a back panel, a top panel, a bottom panel, and opposing side panels; each side panel having an inner panel and an outer panel, the inner panel having a first width defining a width of the inner packaging container, and the outer panel including at least a portion having a second width defining flanges having a width greater than the first width. The inner packaging container is insertable within the outer packaging container such that the flanges extending from the back panel of the inner packaging container exert a biasing force on the hinged lid of the outer packaging container to assure lid closure is maintained.
US10173829B2	Food container with self-actuator A non-liquid food container device comprises: a container for housing the non-liquid food product; and an actuator, wherein the actuator is self-actuated to move the non-liquid food product through the container. The food product can be self-actuated through the container by applying a force to the actuator. The food product can be moved towards an opening in the container for consumption of the food product by a consumer.
US10173824B2	Container for packaging products, in particular food products such as fresh meat products, as well as a method for packaging such products The invention relates to a container for packaging products, in particular fresh products such as meat products. The container comprises a container body with a product space for accommodating a product and a receiving space at least for receiving liquid, preferably liquid from the product. The container body according to the invention comprises partition means that separate the product space and the receiving space from each other. The partition means comprise at least one outlet opening configured to at least discharge liquid from the product space to the receiving space. The container is further provided with at least one resistance element extending into the receiving space, which resistance element surrounds the outlet opening in such a manner that the resistance element prevents the transport of liquid from the receiving space to the product space.
US10173822B2	Air bag packaging arrangement and self-adhesive checking valve An air bag packaging arrangement and a self-adhesive checking valve, the air bag packaging arrangement includes an air bag and an air valve which is the self-adhesive checking valve. The air bag includes first and second cell overlapped layers to form an air chamber and a valve opening. The air valve includes first and second sealing films overlapped between the first and second cell layers, and a strengthening film provided between the first valve film and the first cell film to strengthen a joint strength between the first valve film and the first cell film, so as to prevent the first valve film from being broken, so as to further avoid an air leakage.
US10173821B2	Flexible fitment for flexible container The present disclosure provides a flexible container. In an embodiment, the flexible container includes a first multilayer film and a second multilayer film. Each multilayer film comprises a seal layer. The multilayer films are arranged such that the seal layers oppose each other and the second multilayer film is superimposed on the first multilayer film. The multilayer films are sealed along a common peripheral edge. The flexible container includes a fitment. The fitment comprises a base. The base comprises a polymeric blend of from 60 wt % to 90 wt % ethylene/α-olefin multi-block copolymer and from 40 wt % to 10 wt % high density polyethylene (HDPE). The flexible container includes a fitment seal comprising the base located between the multilayer films. The base is sealed to each multilayer film at a portion of the common peripheral edge.
US10173819B2	Opening system for a container, a method of making the same and a container comprising the opening system An opening system for a container comprising a packaging material having an outside and an inside. An injection molded opening element, wherein the injection molded opening element is attached to the inside of the packaging material at a first point, and extends from the inside of the packaging material and through to the outside of the packaging material. And, wherein the injection molded opening element is attached to the outside of the packaging material at a second point and extends a distance from the second point for opening the container.
US10173816B2	Closure with a removable membrane having an improved separability configuration A closure (20) is provided to selectively permit or restrict communication between the exterior and the interior of a system that has an opening between the exterior and interior. The closure (20) includes a closure body (24) that defines an access passage (30) and a membrane (60) that initially occludes the access passage (30). The connection of the membrane (60) to the body (24) is defined by a tearable portion (68) of material that defines a tear path along which the material can be torn. The tear path has; (A) a first separation path (80) where separation of the membrane (60) from the body (24) initially originates; and (B) a second separation path (90) where separation of the membrane (60) from the body (24) terminates. The second separation path (90) has a generally tapered configuration.
US10173811B2	Dual hinge flip cap closure The disclosed aspects relate to a dual hinge flip cap closure. The closure includes a skirt that operatively engages a container. The closure also includes a top connected to the skirt at a first hinge, wherein the top is movable relative to the skirt. Further, the closure includes a lid operatively attached to the top at a second hinge, wherein the lid is movable relative to the top, and wherein a distal end of the lid is at an opposite of the top relative to the first hinge and the second hinge is between the first hinge and the end of the lid.
US10173809B2	Resealable flexible packages A resealable flexible package is provided comprising polymeric wall panels and a peel-reseal feature sealed therebetween. A peel-off portion is removed to transition the package from a closed position to an open position, removal of the peel-off portion both opening the package and exposing a pressure sensitive adhesive of the peel-reseal feature. The exposed pressure sensitive adhesive is coupled to one of the wall panels and moved into adhesive engagement with an exterior surface of another wall panel to transition the package to a reseated position.
US10173808B2	Bucket handle retainer A bucket handle retainer with a substantially flat rectilinear resilient plate. The plate has an upper tip that corresponds to the inside dimension of the internal cavity of the handle holding portion of a standard five gallon bucket. The plate includes a spring biased finger capable of frictionally engaging the inside wall of the handle holding portion. The plate also includes a holding portion capable of being grasped by a user's fingers to insert or remove the plate from the handle holding portion of the bucket. A preferred embodiment includes the handle retainer is injection molded from nylon plastic.
US10173806B2	Foldable basket, method of manufacture, and method of use of same A foldable basket, attachment mechanism and/or method of manufacturing the same.
US10173802B2	Composite container with separator for forming multiple compartments A composite container is provided for holding one or more products (e.g., snack foods, toys, etc.) in separate compartments within the same container. The container includes a tubular body defining a first end and a second end, and the tubular body extends radially inward at a predefined location between the first and second ends to form a ledge. A separator, such as a paperboard or plastic disk, can be placed on the ledge, such that the separator defines a first compartment on one side of the separator and a second compartment on the other side of the separator. In this way, a product can be stored in the first compartment, and a product can be stored in the second compartment, and the user can have access to both in the same container. Associated methods of manufacturing a composite container with multiple compartments are also provided.
US10173801B2	Polygonal shaped container Disclosed is a polygonal shaped container 101. The polygonal shaped container 101 may comprise a top surface 105 a bottom surface 205 and a plurality of side walls 206. Each edge (201, 203) connecting two side walls of the polygonal shaped container 101 may be filled with additional reinforcement material. The additional reinforcement material along with the polygonal shape of the polygonal-shaped container 101 may facilitate in enhancing compressive strength of the polygonal-shaped container 101. One of the side walls 206 may further comprise a discharge valve 202 fixed entirely within a cavity 204 formed on a lower surface of said one of the side walls 206 such that lowest level of a fluid, contained in the polygonal-shaped container 101, may be discharged from the discharge valve 202. The polygonal-shaped container 101 may be capable of being rolled for portability.
US10173799B2	Tube holder for a filling machine A tube holder is disclosed for carrying a tube to multiple processing stations of a tube filling machine. In one non-limiting embodiment, the tube holder includes a body comprising a receptacle configured for retaining a tube. The tube includes a dispensing end and an opposite open end for filling a cavity therein with a product. A retractable tube shaping device is movably disposed in the tube holder. The shaping device is movable between an extended position and a retracted position. When the shaping device is in the extended position, the shaping device engages the tube proximate to the open end and removes ovality which might interfere with the tube filling operation. In various embodiments, the shaping device comprises a plurality of vertically retractable straightening elements that engage the sidewalls of the tube to ensure circularity of the open tube end.
US10173797B2	Unit for filling containing elements of single-use capsules for extraction or infusion beverages Described is a unit for filling containing elements (2) of single-use capsules (3) for extraction or infusion beverages, comprising: a line (4) for transport of containing elements (2) designed to contain a dose (33) of product; a station (SR) for filling the containing elements (2) comprising: at least a first containing seat (S1) designed to receive a dose (33); a substation (ST1) for forming a dose (33) inside the first containing seat (S1); at least a second containing seat (S2) designed to receive the dose (33) from the first containing seat (S1); a substation (ST2) for transferring the dose (33) from the first containing seat (S1) to the second containing seat (S2); devices (7) for moving the first containing seat (S1) between the forming substation (ST1) and the transfer substation (ST2) and vice versa; a substation (ST3) for releasing the dose (33) from the second containing seat (S2) to a containing element (2); further devices (8) for moving the second containing seat (S2) between the transfer substation (ST2) and the release substation (ST3) and vice versa.
US10173794B2	Packaging machine and method Packaging machine and method for filling dusting product such as bulk material into open-mouth bags via a filling process. The filling process is controlled by weight via a control device and a weighing device. A batching element conveys product and introduces it through a filling spout into an open-mouth bag appended for the filling process. The filling spout is connected with a collecting tank through a flow connection such that a pressure surge occurring during the filling process is utilized for transferring into the collecting tank the displacing air contained in the open-mouth bag and including the dusting product to receive and settle the displacing air in the collecting tank and to deposit at least part of the dust content of the displacing air in the collecting tank as deposited product.
US10173791B2	System and method for magnetically launching projectiles or spacecraft A system and method for magnetically launching projectiles or spacecraft includes an electromagnetic launcher including a launch tube, and a launch craft. The launch tube includes electrically conducting rails energized along the length of the rails, and a transverse direct current magnetic field is generated along the launch tube, and upper and lower conductors and loops of conducting material on the launch craft are provided for magnetic levitation, stabilization and propulsion of the launch craft in cooperation with the transverse direct current magnetic field. A transverse direct current magnetic field is applied to the launch tube and the launch craft during launching of the launch craft, and the launch craft is magnetically levitated and stabilized to minimize contact between the launch craft and the launch tube as the launch craft travels within the launch tube.
US10173790B2	Fuel pump arrangements A fuel pump arrangement has multiple fuel pumps for fitting to aircraft fuel tanks and allowing maintenance of the pumps without requiring access from inside the tanks, particularly one having a housing with two fuel pumps for mounting in or adjacent a single aperture in the wall of a fuel tank, each pump being individually removable from the housing by withdrawal away from the tank. A sleeve is moveable also in the same direction as the pump to obstruct inlets in the housing and isolate the housing from the fuel in the tank so the tank need not be drained.
US10173789B2	Cellular core composite leading and trailing edges A complex-shaped, three-dimensional fiber reinforced composite trailing edge structure may be formed by using counteracting pressures applied to a structural lay-up of wetted fibers placed onto pressurizable members to form continuous fore and aft loops. In turn, the loops may be structurally functional to transfer loads from the trailing edge structure to a wing center section. The trailing structure may include may include fillers and/or a metallic insert, wherein the metallic insert may provide a lightening strike capability for the trailing edge structure.
US10173788B2	Plindow mounted camera system A porthole, a porthole plug in a vehicle, and an aircraft with portholes are provided. The porthole includes an opaque plug with an aperture therethrough. A camera is arranged with a lens aligned with the aperture.
US10173785B2	Combined mode controller and display control unit A combined controller with a panel that has a face and a back, a case attached to the back of the panel. The face of the panel includes a plurality of first primary flight display inputs configured to receive physical inputs for the control of a first primary flight display; a plurality of second primary flight display inputs configured to receive physical inputs for the control of a second primary flight display; and a plurality of flight control inputs configured to receive physical inputs for the control of automated flight behavior.
US10173784B2	Mobile multi-mode power generation system with mode based adjustable drag configuration Various embodiments of the invention can include a portable power system with multiple power generation modes and mode based adjustable drag configuration. Embodiments of the invention include a system with an adjustable inlet ram air inlet, a ram air powered section (e.g. a ram air powered turbine with an adjustable ram air inlet), a fuel powered section, e.g., jet fuel powered auxiliary power unit, which is used when insufficient ram air is present or a power surge requires augmented power generation, and a generator section selectively coupled with the ram air powered section and the fuel powered section.
US10173782B2	Toggle link latch A latch with a unique nesting toggle linkage that extends and retracts a hook via movement of an actuation handle. The linkage links have U-shaped lateral cross sections with a central channel into which the respective links nest when the latch is closed to minimize the overall volume of the latch. The links fold toward each other while closing to reduce the latch's overall length when fully closed. The components of the latch are arranged so that the center of gravity of the latch is positioned in front of a mounting pin; therefore, in applications where the latch swings in the vertical plane, the hook will necessarily hang downwardly away from the keeper when the latch is open. Optionally, a keeper detector prevents the actuation handle from closing if the keeper has not been first captured in the mouth of the hook. A rod-and-cylinder slide mechanism may be employed between the hook body and the mounting pin.
US10173781B2	Systems and methods for applying deformations to a structural surface System for applying deformations to a structural surface, the system may include an actuating unit, operable to produce a periodically variable force which is applied to at least one first location of the structural surface, thereby displacing the structural surface in a plurality of directions at the at least one first location and a passive displacing unit comprising a weight and a displacer supporting the weight and fixed to at least one second location on the structural surface; wherein the structural surface is capable of transferring vibrations between the at least one first location and the at least one second location, so that the displacing of the structural surface at the at least one first location produces forces which are applied to the weight via the structural surface and the displacer, bringing the weight to resonance, thereby displacing the structural surface in a plurality of directions at each of the at least one second location.
US10173778B2	Button assembly for seat position control Button assemblies for controlling a seat position and for mounting on a seat panel are provided. The button assemblies may have a button housing having a portion that is configured to position over edges of an opening in the seat panel. One or more flexible retaining members integral to or attached to the button housing are configured to compress through the opening in the seat panel and expand therein positioned opposite an inner surface thereof upon insertion, securing the assembly within the opening.
US10173775B2	Modular thrust system Disclosed herein is one embodiment of a thrust system that includes at least one modular thrust unit and at least one control module. The at least one modular thrust unit includes a base that is made from structural members that are inter-connectable in a plurality of different structural configurations. The at least one modular thrust unit further includes at least one thrust generator coupleable to the base in a thrust configuration and at least one power source operable to deliver power to the at least one thrust generator. The at least one control module is coupleable to the at least one modular thrust unit and operable to control at least one of the at least one thrust generator and the at least one power source.
US10173767B2	Aircraft with drive element coupled to gearbox housing exterior An aircraft is provided and includes a gearbox housing through which a drive shaft configured to drive propeller rotation extends and a pitch control apparatus. The pitch control apparatus includes a drive element coupled to an exterior of the gearbox housing and an annular electro-mechanical actuator (EMA) configured to convert rotational energy generated by the drive element to thereby control a pitching of propeller blades about corresponding pitch axes.
US10173765B2	Pressure bulkhead apparatus Pressure bulkhead apparatus is disclosed. An example bulkhead apparatus includes a frame and a plurality of beams radially spaced relative to a longitudinal axis of the frame. A beam from the plurality of beams has a first end and a second end. A beam end assembly couples the second end of the beam and a stringer of a fuselage. The beam end assembly enables the second end of the beam to move relative to at least one of the frame or the stringer.
US10173763B1	Balloon launching apparatuses Aspects of the disclosure relate to techniques for launching high-altitude balloons. In one aspect, a balloon launching system is provided. The balloon has a balloon envelope, a payload attached to the balloon envelope and a launching projection. The launching system includes a releasable restraint attached to the balloon between an apex and bottom of the balloon envelope. The releasable restraint is arranged to temporarily hold the balloon envelope. The launching system also includes a payload positioning assembly. The payload positioning assembly is configured to position the payload during launch of the balloon and includes a member configured to attach to the launching projection. When attached, the member is also configured to maintain the position of the payload relative to the balloon while the releasable restraint is temporarily holding the balloon envelope.
US10173762B1	Trolling motor mounting assembly A trolling motor mounting assembly for pivotally mounting a trolling motor includes a base that is configured to couple to a boat. A connector, which is hingedly coupled to a first end of the base, is configured to selectively couple to a shaft of a trolling motor. A first fastener is coupled to the connector. A bar is hingedly coupled to the base proximate to a second end of the base. A second fastener is coupled to a second endpoint of the bar. An actuator is coupled to the bar and is operationally coupled to the second fastener. The bar can position the second fastener to couple to the first fastener to fixedly vertically position the shaft. The actuator can compel the second fastener to decouple from the first fastener. The bar and the connector can pivot so that the shaft is parallel to the base and the bar.
US10173758B2	Marine lifting apparatus A catamaran lifting apparatus is disclosed for lifting objects in a marine environment. The apparatus includes first and second vessels that are spaced apart during use. A first frame spans between the vessels. A second frame spans between the vessels. The frames are spaced apart and connected to the vessels in a configuration that spaces the vessels apart. The first frame connects to the first vessel with a universal joint and to the second vessel with a hinged connection. The second frame connects to the second vessel with a universal joint and to the first vessel with a hinged or pinned connection. Each of the frames provides a space under the frame and in between the barges that enables a package to be lifted and/or a marine vessel to be positioned in between the barges and under the frames. In this fashion, an object that has been salvaged from the seabed can be placed upon the marine vessel that is positioned in between the barges and under the frames.
US10173756B2	Configurable water activity board Embodiments of water activity board 10 that may be configured with several components 210A-H to form a WABS 200, where the components 210A-H may be securely and removably coupled to the board 10 via one or more rail modules 100A-I. Other embodiments may be described and claimed.
US10173754B2	Pontoon boat cover system A cover system for a boat includes a bimini frame securable to the boat and displaceable among an open position, a storage position, and a cover position. A flexible top is coupled with the bimini frame, and a cover is positionable over the bimini frame with the bimini frame in the cover position. The bimini frame thus functions as a support structure for a mooring or trailering cover. With the described bimini frame, one cover size can fit multiple seating and deck configurations without the need for a separate cover design for the various configurations.
US10173745B1	Mechanism for securing a payload in a desired angular orientation A mechanism for securing a payload in a desired angular orientation. The mechanism includes a gear; a spline shaft coaxially mounted to engage the gear in a first position on a longitudinal axis of the shaft and to disengage the gear in a second position of the longitudinal axis of the shaft, the gear or the shaft being coupled to the payload whereby an angular orientation of the payload may be changed from a first angle to a second angle when the gear is in the second position; and a spring assembly mechanically coupled to the gear and spline shaft to restore the shaft to the first position from the second position. The gear and the shaft have matching and interlocking male/female splines. The spline shaft is capped at a proximal end thereof. The cap is substantially transverse to the longitudinal axis of the shaft and having an aperture therein at the center thereof. The spring assembly includes a bolt mounted for reciprocal movement in the shaft along the longitudinal axis thereof, the bold having a bolt head at a distal end thereof and being secured to the gear at a proximal end of the bolt. The spring assembly further includes a spring mounted between the bold head and the cap. In the illustrative embodiment, the mechanism is implemented in an adjustable handlebar assembly.
US10173744B2	Bicycle stabilizer devices and methods of stabilizing a bicycle A bicycle stabilizer device includes a first post attached to a handlebar stem of a bicycle and a second post attached to upper frame portion of the bicycle; and a stabilizer bar configured to be reversibly connected between the first and second posts. Stabilizing a bicycle includes providing a stabilizer bar comprising a front portion end and a rear portion, attaching the second end to an upper portion of a bicycle frame. A post is disposed along a handlebar stem of the bicycle. The first end of the bar is reversibly connected to the post, the reversibly connecting stabilizing a front wheel of the bicycle to remain in a forward position.
US10173742B2	Rear portion structure of saddle-ride type vehicle One embodiment provides a rear portion structure of a saddle-ride type vehicle. The structure includes: seat frames inclined rearward and upward and supporting a riding seat; and a rear cowl having an upper cowl and a lower cowl. The upper cowl includes: a first cowl; and a second cowl which is connected to the first cowl and forms an opening upper edge portion of an opening for exposing a tail light. The lower cowl includes: a third cowl; and a fourth cowl which is connected to the third cowl and forms an opening lower edge portion of the opening. An approximately-U-shaped recessed portion is opened at a rear end of the third cowl. The fourth cowl forms the opening lower edge portion while covering the U-shaped recessed portion.
US10173736B2	Aerodynamic device for motor-vehicle Aerodynamic device for a motor-vehicle including a panel structure located under the front part of the motor-vehicle and elastically biased towards a raised position and configured to be moved towards a lowered position due to an airflow which invests the motor-vehicle during travel. The aerodynamic device includes a bag structure provided inside of a cavity for receiving in its interior the airflow which invests the motor-vehicle during travel, in such a way that above a predetermined threshold value of the motor-vehicle speed, the bag structure is inflated and pushes the panel structure towards its lowered position.
US10173735B2	Vehicle cargo tailgate enclosure An improved vehicle cargo tailgate enclosure particularly adapted for ease of installation and removal. The tailgate enclosure comprises two side walls and a rear wall. The rear wall is configured to slope upwardly and rearwardly to provide additional storage space to a cargo bed of a vehicle. The cargo tailgate enclosure further comprises tubular members which comprise a non-circular cross section which provide exceptional strength a structural stability to the cargo tailgate enclosure. The cargo tailgate enclosure further comprises a plurality of upright members. Some of the upright members are configured to attach the cargo tailgate enclosure to a vehicle and to cap the tubular members. Other upright members are configured to support the tailgate enclosure against the surface cargo bed or a tailgate of a vehicle.
US10173733B2	Multi-purpose stud mount apparatus A multi-purpose stud mounting apparatus is provided to mountably and detachably couple a threaded mounting stud of a motor vehicle body or internal combustion engine and a functional component, such as an air filter housing air intake duct or air intake resonator so as to releaseably and supportively mount the functional component to the vehicle.
US10173731B2	Side chassis structure of vehicle Present application discloses side chassis structure. Side chassis structure includes: apron reinforcement member; fender panel covering outside of the apron reinforcement member; and brackets connected to the fender panel. At least one of the brackets includes: main body including support portion supporting fender panel; front leg portion extending downward from front end of inner portion of main body in vehicle width direction, front leg portion being attached to apron reinforcement member; and rear leg portion which extends downward from rear end of the main body, rear leg portion being attached to apron reinforcement member. Front leg portion has inner slotted hole having long axis extending in vehicle width direction, and outer slotted hole which is formed outside inner slotted hole in vehicle width direction, outer slotted hole having long axis longer than long axis of inner slotted hole.
US10173730B2	Vehicle front structure An outrigger is connected to a front end part of an apron upper member, and further, is extended from its connected part up to that area of a front side member which is on its front end side and on its outer side in a vehicle width direction so as to be connected to the front side member. One end part of a connecting support member is connected to a connecting portion between the outrigger and the apron upper member. The connecting support member extends inward in the vehicle width direction in a plan view of a vehicle from its connected part, so as to be connected to the front side member.
US10173729B2	Vehicle pillar structure The present disclosure provides a vehicle pillar structure including: a pillar portion extending along a vehicle transverse direction outer side end portion of a windshield glass, the pillar portion including: a pair of side portions configuring a vehicle transverse direction inner side and outer side portion of the pillar portion and being configured by an opaque material, and transparent portions provided between the pair of side portions and being configured by a transparent material; reinforcing portions configured by an opaque material, spanning between the pair of side portions, formed integrally with the transparent portions, and reinforcing the pillar portion; and upper surfaces and lower surfaces of the reinforcing portions extending along a vehicle longitudinal direction, or inclining toward a vehicle lower side on progression towards a vehicle longitudinal direction outer side, as seen in a cross-section viewed from a vehicle transverse direction inner side.
US10173724B2	Model based driver torque estimation A control system for a power steering system includes an error module that generates an error signal based on a difference of an estimated output vector and an output vector, a scaling module that calculates a feedback correction signal based on the error signal and an observer gain value, an extended state vector estimation module that determines an extended state vector estimate based on the feedback correction signal and a motor torque command, and a gain module that applies a gain to the extended state vector estimate to generate an estimated driver torque signal, the estimated driver torque signal is applied in control of the power steering system.
US10173721B2	Steering motor Disclosed is a steering motor, comprising a spring damping valve, and an oil distributor which is fitted with the spring damping valve to form a cavity in which a buffering assembly is provided. A cylinder assembly is provided on a lower side of the oil distributor, and comprises a cylinder, an elastic oil bag provided in the cylinder, and a piston which is provided in the cylinder and fixedly connected to the elastic oil bag, the piston being capable of sliding axially along the cylinder. In addition, the oil distributor is further provided with an oil flow passage; the spring damping valve protrudes out of a hollow column having an inner cavity; a directional control valve having a valve core is inserted in the cavity of the hollow column; the hollow column is further provided with an oil flow port in communication with the oil flow passage; an oil inlet groove is provided on and in communication with the oil flow port; and the valve core protrudes into the hollow column and is fitted with the oil flow port and the oil inlet groove. The steering motor adopts an oil passage combination design to simplify the structure, and also adopts the elastic oil bag to reduce the frictional wear of a shock absorption mechanism, so as to prolong the service life of steering motor and reduce the costs.
US10173719B2	Electric power steering apparatus An electric power steering apparatus that calculates a first current command value based on at least a steering torque and performs an assist-control of a steering system by driving a motor based on the first current command value, including: a configuration of a model following control including a viscoelastic model as a reference model within a predetermined angle at front of a rack end, wherein an offset is given to input or output of the viscoelastic model for preventing an overheat, resulting in suppressing a rack end hitting.
US10173717B2	Electric power steering apparatus [Problem]An object of the present invention is to provide an electric power steering apparatus that can accurately suppress a vibration, a noisy sound and so on whose vibration source is a power spectrum occurring from a relationship between an operation period of torque control and an operation period of current control, and which occur regardless of presence or absence of a mechanical resonance.[Means for solving the problem]In an electric power steering apparatus that comprises a torque control section which calculates a current command value based on at least a steering torque and a current control section which controls a motor current flowing to a motor based on the current command value, an operation period of the torque control section is longer than or equal to an operation period of the current control section, and the current control section comprises a specific frequency band eliminating section that attenuates at least one frequency component having a frequency obtained by multiplying about half of an operation frequency of the torque control section by a natural number in the current command value.
US10173715B2	Rotating electrical machine A stator is fixed to a frame of an electric motor. A rotor is rotatably mounted to the frame to face the stator in a radial direction. A heat sink, to which a control substrate is attached, is mounted in an opening of the frame. A motor cover is attached to a front end of the frame to cover the heat sink. An adhesive groove, which has a fixed depth and is filled with an adhesive, is formed on the front end. A joining portion is formed on the rear end of the motor cover, and is inserted into the adhesive groove is an axis of rotation direction to join the motor cover with the frame in a liquid-tight manner.
US10173713B2	Steering wheel decorative member A steering wheel decorative member is used for being attached to a resin member covering a periphery of a ring core of a steering wheel. The decorative member includes a hollowed-out portion including an opening that is formed on a surface of the decorative member facing the resin member and that extends in a longitudinal direction of the decorative member.
US10173709B2	Pallet truck handle assembly A pallet truck handle assembly is provided, including a handle hinge seat, a handle control head, and a removable handle tube having a first end and a second end. The first end of the removable handle tube is removably connected to the handle hinge seat by one or more fasteners, and the second end of the removable handle tube is connected to the handle control head. The handle assembly further includes a handle control cable or handle wiring harness having a first end and a second end. The first end of the handle control cable or handle wiring harness is located proximate the first end of the removable handle tube and the second end of the handle control cable or handle wiring harness is connected to the handle control head, and the handle hinge seat has a support member that receives a chassis control cable or a chassis wiring harness.
US10173705B2	Cart suspension system A cargo dolly having a suspension assembly incorporated therein, wherein the suspension assembly is adapted to maintain the dolly at a prescribed height relative to an underlying surface. Thus, as cargo is loaded onto the dolly, and subsequently unloaded from the dolly, the dolly will substantially remain at the same height, which facilitates use of the dolly with standardized loading docks, such as loading docks associated with aircraft.
US10173704B2	Lifting apparatus A lifting apparatus, such as may be used with gas cylinders such as welding gas cylinders, comprising a frame (1) and a carriage (3), the carriage being mounted on the frame through a mounting (9), the mounting (9) allowing the carriage (3) to rotate relative to the frame (1) and to slide linearly relative to the frame (1) constrained to a path, the carriage (3) being provided with a loading surface (2, 12, 24) for a load (101). The mounting may comprise a bar (19) typically on the carriage (3) held captive in a track (25) typically on the frame (1).
US10173701B2	Method and system for LED based incandescent replacement module for railway signal An apparatus including a housing; a solid state light source disposed in the housing to emit light therefrom; and a filter disposed in or on the housing in optical communication with the solid state light source to reshape a radiometric spectrum of the light emitted by the solid state light source to substantially replicate a radiometric spectrum of an incandescent filament light source.
US10173694B2	Traveling control device for vehicle A traveling control device for a vehicle includes an electronic control device. The vehicle includes drive power sources. The electronic control device is configured to select, according to a traveling state of the vehicle, a traveling mode from among traveling modes. One or more predetermined drive power sources is used for driving the vehicle in each traveling mode. The one or more predetermined drive power sources in the respective traveling modes is different from each other. The electronic control device is configured to drive the vehicle by using the selected traveling mode, switch between automatic driving by automatic driving control and manual driving by a driving operation from a driver, and when the selected traveling mode switches, inhibit, after switching of the selected traveling mode starts, switching between the automatic driving and the manual driving until the switching of the selected traveling mode is completed.
US10173693B2	Method for operating a motor vehicle and associated motor vehicle Method for operating a motor vehicle having at least one sensor for detecting a user state and/or at least one parameter from which the user state can be deduced, wherein a function and/or a device of the motor vehicle is automatically controlled by a control device, depending on a detected user state and/or a detected change in the user state, a level of autonomy which specifies to what extent a function and/or a device of the motor vehicle is controlled automatically by a control device of the motor vehicle or is manually controlled by a user, changes at least one function and/or at least one device of the motor vehicle and the function and/or the device is controlled according to the level of autonomy.
US10173691B2	Vehicle sensor calibration using wireless network-connected sensors Method and apparatus are disclosed for vehicle sensor calibration using wireless network-connected sensors. An example disclosed vehicle includes a communication controller and a sensor manager. The example communication controller communicatively couples to a network associated with a facility. The example sensor manager determines when the vehicle is proximate the facility. Additionally, the sensor manager calibrates sensors of the vehicle based on a measurement data of sensors installed at the facility that are communicatively coupled to the network.
US10173690B2	Vehicle, vehicle controller, vehicle control method, and medium storing vehicle control program A vehicle includes a detection section and a automated drive controller. The detection section detects actual behavior of the vehicle. The automated drive controller generates a automated drive action plan for the vehicle, issues an instruction relating to behavior of the vehicle based on the generated action plan to a drive source controller that controls a drive source of the vehicle, and compares predicted behavior of the vehicle predicted based on the issued instruction and actual behavior of the vehicle detected by the detection section. In cases where the predicted behavior of the vehicle and the actual behavior of the vehicle detected by the detection section differ from each other by more than a preset range, the automated drive controller issues an instruction to decelerate the vehicle to a brake device of the vehicle.
US10173689B1	Recreational vehicle and integrated body control and weight sensing system In accordance with one embodiment of the present disclosure, a recreational vehicle is provided comprising a vehicle body supported by at least one axle assembly, a plurality of operational components, at least one weight-sensing component, a body control module in communication with the operational components, a weight processing module in communication with the weight-sensing component, and a user interface. The user interface is in communication with the body control module and the weight processing module and comprises user prompts for (i) associating particular operational components with the recreational vehicle and (ii) associating a particular weight-related parameter with the recreational vehicle. The weight processing module, the weight-sensing component, and the user interface are structured to generate an indication of vehicle weight at the user interface. The indication of vehicle weight is at least partially dependent upon the particular weight-related parameter associated with the recreational vehicle at the user interface. Additional embodiments are disclosed and claimed.
US10173688B2	Method of determining driving tendency and system of controlling shift using the same A method of determining a driving tendency and a system of controlling shift using the same are disclosed. A system of controlling shift for a vehicle may include: a data detector detecting data for a shift control; and a controller determining a short term driving tendency index and a long term driving tendency index, and controlling an engine or a transmission according to the long term driving tendency index, wherein the controller determines the short term driving tendency when an accelerator pedal position reaches a predetermined position value while the vehicle is coasting.
US10173687B2	Method for recognizing vehicle driver and determining whether driver can start vehicle Provided are systems and methods for increasing vehicle safety by determining whether a driver can operate a vehicle based on whether the physical status of the driver and the identity of the driver are acceptable. A first set of sensors may determine the physical status of the driver. The first set of sensors may include an electrocardiogram detection component, an alcohol detection component, a body temperature detection component, and a photography component, among others. A second set of sensors may determine the identity of the driver. The second set of sensors may a fingerprint detection component, an electrocardiogram detection component, and a photography component, among others. When it is determined that the physical status of the driver is unacceptable, the method may include activating an automatic driving system.
US10173686B2	Control device for multi-disc lock-up clutch Lock-up clutch engagement hydraulic pressure learning control can be precisely performed by starting lock-up clutch engagement control and executing the lock-up clutch engagement hydraulic pressure learning control after execution of shift control is completed, in a case where the lock-up clutch engagement control is limited in a shift stage before execution of the shift control, when the shift control is executed in a state where a multi-disc lock-up clutch is released. Meanwhile, a decrease in fuel efficiency performance and a direct steering feeling is minimized by starting the lock-up clutch engagement control during shift control in a case where the lock-up clutch engagement control is not limited.
US10173683B2	Vehicle control device and vehicle control method A vehicle control device disengages a clutch provided between an engine and a driving wheel at a brake-off and an accelerator-off during traveling of the vehicle, and stops the engine and carries out inertia traveling. The vehicle control device starts the engine by the push-start by engaging the clutch and by transmitting the power of the driving wheel to the engine, if it is determined that a brake pedal has been depressed during the inertia traveling.
US10173682B2	P-range engagement method of vehicle and control device thereof A P-range engagement method of the vehicle and a device thereof are disclosed. The P-range engagement method is applied to the vehicle equipped with an electronic shift lever, and the method includes performing the vehicle stopping process based on detection of stopping of a traveling vehicle through a control device, holding wheel disks of the vehicle through a controller that is controlled by the control device, comparing the vehicle stopped time period, which is measured by the control device, with a predetermined reference value stored in the control device to determine whether the vehicle stopped time period exceeds the predetermined reference value, and upon determining that the vehicle stopped time period exceeds the predetermined reference value, determining whether conditions for performing P-range engagement are satisfied, and upon determining that the conditions for performing the P-range engagement are satisfied, completing the P-range engagement.
US10173681B2	Method and device for automatically regulating vehicle longitudinal dynamics Automatically regulating vehicle longitudinal dynamics in accordance with a preceding vehicle includes determining a first state variable dependent on vehicle acceleration, a second state variable dependent on engine drive torque, a third state variable dependent on the operating state of at least one permanent brake, and information about the preceding vehicle, and adjusting at least one regulating parameter of a regulation function and regulating the longitudinal dynamics depending on the at least one regulating parameter. A first sensor determines the vehicle speed, a second determines the drive torque, a third determines the operating state of the at least one permanent brake, a fourth determines information about the preceding vehicle and an analysis/adjustment/regulating unit analyzes the speed, the drive torque, the operating state of the at least one permanent brake and the information about the preceding vehicle, adjusting the at least one regulating parameter and regulating the vehicle longitudinal dynamics depending on the at least one regulating parameter.
US10173677B2	System and method for controlling vehicle speed to enhance occupant comfort A method for operating a speed control system of a vehicle is provided. The method comprises receiving one or more electrical signals representative of vehicle-related information. The method further comprises determining, based on the signals representative of vehicle-related information, whether one or more predetermined conditions are met. The method still further comprises automatically determining a baseline set-speed for the speed control system when it is determined that at least certain of the one or more predetermined conditions are met. The method yet still further comprises adjusting the baseline set-speed to determine an instantaneous set-speed of the speed control system based on a signal indicative of a desired comfort level. A speed control system comprising an electronic control unit configured to perform the above-described methodology is also provided.
US10173676B2	Travel assist device and method of controlling travel assist device Provided are a travel assist device capable of producing, in a preferred manner, warning vibrations notifying deviation of a vehicle with respect to a travel path, and a method of controlling the same. A travel assist device includes a travel assist control device that notifies a driver about an anti-deviation direction or a deviation direction by making a steering angular acceleration in the deviation direction and the steering angular acceleration in the anti-deviation direction different from each other when producing warning vibrations, wherein a time-derivative value of a steering angle of a steering wheel is defined as a steering angular velocity, and a time-derivative value of the steering angular velocity is defined as the steering angular acceleration.
US10173674B2	Traction based systems and methods A first vehicle includes: steering, brakes, memory, sensors, and processor(s) configured to: determine, with the sensors: the first vehicle's acceleration, a second vehicle's acceleration; compute a theoretical collision velocity (TCV) between the first vehicle and the second vehicle based on the accelerations; apply a function or generate a command based on the TCV and a selected coefficient of kinetic friction (COF).
US10173671B2	Sensor calibration in a parking facility A method for calibrating an internal sensor in a vehicle with an external sensor which is designed to detect external positional data dependent on a position of the vehicle. The method includes: detecting the external positional data using the external sensor; sending the external positional data to the vehicle and filtering the internal positional data based on the external positional data and dependent on the position of the vehicle and by an internal sensor.
US10173670B2	Parking assistance device A parking assistance device includes: a parking space candidate detection unit estimating positions of obstacles based on data of distance to the obstacles at both sides of a host vehicle, and detecting a parking space candidate at the sides of the vehicle; an image selection unit selecting two or more captured images in which an inner side surface of an obstacle adjacent to the parking space candidate is captured; a stereo image processing unit performing stereo image processing on the two or more captured images and calculating a three-dimensional point group of the obstacle; a position determination unit determining a position of the obstacle on the parking space candidate side based on the calculated three-dimensional point group; and a parking space correction unit correcting a position of the parking space candidate based on the determined position of the obstacle on the parking space candidate side.
US10173657B2	Vehicle braking device Provided is a braking device capable of suppressing an overshoot or undershoot in output pressure. This vehicle braking device is configured such that a pressure adjustment unit has a piston which is driven by the difference between force corresponding to pilot pressure and force corresponding to output pressure, and a control unit estimates, on the basis of a stroke-related value regarding the amount of movement of the piston, the amount of change of the output pressure that changes even after switching from pressure increase control or pressure reduction control to holding control of the output pressure, and controls a valve unit on the basis of the estimated amount of change of the output pressure.
US10173656B2	Negative pressure type booster device A movable diaphragm of a negative pressure type booster device includes an annular rubber diaphragm and an annular metal plate. The diaphragm is airtightly pinched by the housing at an annular outer peripheral bead portion formed at an outer peripheral edge of the diaphragm, and airtightly secured to an outer peripheral portion of a valve body, together with an inner peripheral portion of the plate, at an annular inner peripheral bead portion formed at an inner peripheral edge of the diaphragm. Between the outer peripheral bead portion and the inner peripheral bead portion, there are formed a folded portion having a curved portion toward the front and continuous with the outer peripheral bead portion at an outer peripheral area, and an annular portion continuous with an inner peripheral area of the folded portion and with the inner peripheral bead portion.
US10173653B2	Method for determining a pressure/volume characteristic curve of a wheel brake Method and system for determining a pressure/volume characteristic curve of a wheel brake in a motor vehicle brake system having an electrically controllable pressure supply device connected hydraulically to wheel brakes and can output a pressure medium volume for activating the wheel brakes. The pressure medium volume which is output by the pressure supply device can be determined. An electrically actuable inlet valve per wheel brake disconnects the connection between the wheel brake and the pressure supply device. During one or more service brake operations of the motor vehicle wheel brakes are activated by the pressure supply device, the pressure medium volume output by the pressure supply device in order to activate the wheel brakes is determined and the pressure/volume characteristic curves of the wheel brakes are determined on the basis of pressure medium volumes output by the pressure supply device during one or more service braking operations are determined.
US10173652B2	Hydraulic trailer brake circuit for adjustable gain and improved stability A braking system of a work machine includes a pressurized fluid supply, a base valve fluidly coupled to the supply, a proportional control valve fluidly coupled to the supply, and a fluid output configured to be fluidly coupled to a braking system of a trailer. A first fluid path is selectively fluidly coupling the supply to the fluid output via the base valve, and a second fluid path is selectively fluidly coupling the supply to the fluid output via the proportional control valve. The base valve includes a predefined fixed gain and the proportional control valve includes an adjustable ratio.
US10173649B2	Brake master cylinder A brake master cylinder is disclosed. A brake master cylinder comprises a cylinder body having a hollow, a piston provided to reciprocate in the hollow, and a sensor module connected on the cylinder body and configured to sense a movement according to a reciprocating motion of the piston. And the sensor module includes a sensor housing coupled to a guide hole formed parallel with the hollow of the cylinder body and having a hollow therein in a length direction, a magnet installed to be slidable through the hollow of the sensor housing, and an actuating member coupled to the piston and configured to move the magnet according to a movement of the piston.
US10173643B2	Object detection for vehicles A vehicle includes a pair of cameras disposed on the vehicle and oriented to view an entrance to the vehicle. The vehicle also includes a processor configured to compare a profile image of a passenger's facial feature from one of the pair with a frontal image of the passenger's facial feature from the other of the pair. The processor is configured to lock the entrance to the vehicle in response to the facial features being different.
US10173642B2	Telematics system with PIN-controlled external SIM to prevent vehicle piracy The operation of a conventional cellular telecommunications transceiver that forms part of a vehicle's telematics system can be selectively changed in order to provide telephone calls by providing the transceiver with a second and different SIM card. Providing a second SIM card, however, will disable telematics service that can include stolen vehicle tracking. A personal identification number or PIN is thus required in order for the information that is stored in an external, user-provided SIM card to be used by a telematics system transceiver rather than the information stored in a built-in SIM card that is provided by a telematics system operator/provider.
US10173639B1	Seat belt indicator light The seat belt indicator light is a supervisory system monitors a seat belt reminder signal within a vehicle. The seat belt indicator light comprises a visual indicator, a control system, and a communication system. The visual indicator monitors the seat belt reminder signal and illuminates the externally visible signal when the seat belt reminder signal is illuminated. The logic module monitors and logs status of the seat belt reminder signal while the vehicle is in operation. The communication system provides remote and local wireless communication services between the control system and an appropriate authority.
US10173633B2	Hybrid inflator and vehicle safety system comprising said hybrid inflator as well as method of forming a shock wave The invention relates to a hybrid inflator (10) includes at least one combustion chamber (15) in which propellant charge is arranged and which has a discharge end (20), the propellant charge being formed of at least one propellant element (26), at least one igniting unit (12) by which the propellant charge can be ignited. The hybrid inflator (10) also includes at least one bursting element (14, 14′, 14″) which in the inactivated state of the hybrid inflator (10) delimits the combustion chamber (15) against a gas supply chamber (16) at the discharge end (20). The bursting element (14, 14′, 14″) and a restraint element (18, 18′, 18″) maintain the propellant charge in its position and/or the bursting element (14, 14′, 14″) and the propellant charge delimit a shock gas volume (SGV), wherein in the activated state of the hybrid inflator (10) the shock gas volume (SGV) acts on the bursting element (14, 14′, 14″) like a gas pressure spring.
US10173627B2	Method and device for maintaining an actuator for an airbag control device A method for maintaining an actuator for an airbag control device. The method has a step of impressing an electric current flow through the actuator using an electric voltage having a voltage value. In addition, the method has a step of ascertaining an electric measuring current through the actuator. Here, the electric measuring current through the actuator occurs on account of the impressed electric current flow through the actuator. In addition, the method has a step of executing a comparison of the electric measuring current through the actuator to a threshold value. Moreover, the method has a step of adjusting the voltage value of the electric voltage for impressing the electric current flow through the actuator as a function of the comparison.
US10173626B2	Capacitive vehicle seat occupancy detection system with detection of vehicle seat heater member interruption A capacitive detection system for detecting occupancy of a vehicle seat includes a signal generating unit and a signal evaluation unit. The vehicle seat has a seat heater member configured for receiving time-varying output signals of the signal generating unit. The signal evaluation unit is configured to generate an output signal that is indicative of the seat heater member to be defective, if the sensed capacitance of the seat heater member is less than a second predetermined threshold value for the sensed capacitance.
US10173620B2	Protection device for vehicle chassis A protection device (100) for a vehicle chassis includes a first flange plate (211) obliquely disposed to a rear side of a beam (10); a second flange plate (221) having a front end face abuts against a rear end face of the first flange plate (211), and connected to the first flange plate (211) through a bolt; a left side plate (222) and a right side plate (223) provided in perpendicular to a rear end face of the second flange plate (221); a connecting plate (224) having a left end connected to the left side plate (222) and a right end connected to the right side plate (223), and arranged close to front ends of the left side plate (222) and the right side plate (223); and a bearing member provided to the rear end face of the second flange plate (221) and located between the left side plate (222) and the right side plate (223).
US10173616B2	Compressed air system for a motor vehicle A compressed air system for a motor vehicle with an air supply system, including: an electric drive motor, which can be controlled for variable speed, an air compressor coupled to be driven by the electric drive motor, an electric power supply for supplying electric power to the electric drive motor, at least one air reservoir connected with the air compressor to receive air from the air compressor, an air utilization system connected to the at least one air reservoir to receive air from the at least one air reservoir, a controller to control the speed of the electric drive motor. The controller controls the electric drive motor to determine the speed of the electric drive motor so that during filling of the air reservoir, when the pressure level in the air reservoir passes a setpoint that is between a minimum level and a higher cut off pressure level, the controller changes the compressor speed so that specific power consumption per unit mass of air compressed is decreased.
US10173614B2	Power supply device for auxiliary device battery A vehicle mounted charger converts external power into drive power, and supplies the power to a drive battery. A first converter supplies the power to an auxiliary device battery by converting the external power into the power for an auxiliary device. A second converter supplies the power to the auxiliary device battery by converting the drive power which is stored in the drive battery into the power for the auxiliary device. In a normal charging mode, the auxiliary device battery is charged by the first converter. Moreover, in a travelling mode or a rapid charging mode, the auxiliary device battery is charged by the second converter.
US10173612B2	Wiring attachment assembly and wiring system for a motor vehicle A wiring attachment assembly includes a stud having at least one channel, a gripping washer engaging the stud in the at least one channel and a wiring conduit including a receiver engaging and holding the stud. A wiring system, incorporating the wiring attachment assembly and an insulator element, as well as a method of wiring for a power folding seat are also disclosed.
US10173610B2	Vehicle identification number carpet cover A carpet cover is provided for a vehicle identification number. That carpet cover includes a first layer of material having a first window and a first flap closing the first window as well as a second layer of material having a second window and a second flap closing the second window. This second window overlies and overlaps the first window and the second flap overlies and overlaps the first flap.
US10173606B2	Structure for attaching in-vehicle apparatus A structure is for attaching an in-vehicle device including a display 20 standing on a dashboard 1 of a vehicle, and a controller 30 placed inside the dashboard 1. The structure includes a connecting bracket 40. The controller 30 is fixed to the dashboard 1. The controller 30 and the display 20 are connected together via the connecting bracket 40. The connecting bracket 40 is attachable to and detachable from the controller 30 and the display 20 independently.
US10173605B2	Display unit for a vehicle An entertainment system including a removable seat-back display unit and a docking station. The seat-back display unit can include a rotating latch butterfly release mechanism that prevents unauthorized release of the display unit from the docking station. The system can include a three-point attachment system that provides additional protection against accidental detachment of the display unit, and provide safety in the event of partial dislodging. The system can include a current control pin system that ensures that current is not provided from the docking station to the display unit until the respective connectors have been properly engaged. The system can further include a floating pin connector dock that can allow for installation of the display unit even when the connectors of the display unit and docking station become misaligned. The system can also include a heat dissipation system that employs the docking station to share the heat dissipation load with the display unit.
US10173603B2	Vehicle side wall storage In one or more embodiments, a storage system is provided for use with a vehicle including a side wall and a rear wheel positioned below the side wall; the storage system includes a storage container receivable within an elongated space defined between inboard and outboard panels of the side wall, the storage container including front and rearward portions respectively positioned front and rear to the rearmost point of the rear wheel. The storage system may further include a leg portion for supporting the rearward portion of the storage container. The leg portion may be adjustable in length and may be attached to the elongated space or to the storage container.
US10173601B2	Carrier apparatus for vehicle A carrier apparatus for a vehicle may include a bumper back beam to be drawn out and received in the bumper back beam, an adapter cover rotatably disposed at an upper portion of the carrier in an up and down direction and having an upper portion depressed to form an installation space, and a loading cover detachably connected to the installation space of the adapter cover and provided with a fixture for fixing a luggage loaded at an upper portion thereof.
US10173596B2	Removable article carrier for a vehicle An apparatus for receiving articles in a vehicle cargo area is provided. A collapsible carrier includes at least one locator projection, and a support for supporting the carrier includes a receiver for receiving the locator projection of the carrier to restrict movement of the carrier laterally while allowing the carrier to be separated from the support for removal from the vehicle cargo area. The support may be a platform adapted for raising during movement from a stowed, non-erect position in the vehicle cargo area to an erect, deployed position rearward of the non-erect position to facilitate accessing any articles in the carrier. A related method is also disclosed.
US10173595B1	Portable truck step A portable apparatus comprising a truck step for use in climbing into a cargo area of a pickup truck is described. The system provides a deployable step system that can be stowed securely out of the way in the cargo area of a pickup truck when not in use.
US10173587B2	Brake light sensor module A brake light sensor module includes: a retainer which is provided to move together with an operation element of a master cylinder in response to a depression of a brake pedal; an operation rod which is connected to the retainer so as to move together with the retainer; an elastic member which is installed in the master cylinder; a signal transmitting element which is installed in the master cylinder, one end of the signal transmitting element being elastically supported by the elastic member, and the other end of the signal transmitting element being supported by the operation rod; and a sensor which is installed in the master cylinder so as to be operated by the signal transmitting element.
US10173576B2	Vehicle lighting structure A first lamp assembly has a first attachment surface, a first transparent surface, a first side surface extending from the first transparent surface to the first attachment surface, and a first lighting member positioned to emit light through a portion of the first side surface. A second lamp assembly has a second attachment surface, a second transparent surface opposite the second attachment surface and a second side surface extending from the second transparent surface to the second attachment surface. The second side surface has a first projection extending therefrom that defines a first light deflecting surface such that when the second side surface and the first side surface are adjacent to one another with the light deflecting surface and first lighting member being aligned, the first light deflecting surface reflects and disperses light in a first area between the first lamp assembly and the second lamp assembly.
US10173575B2	Modular bumper attachment A modular bumper attachment system configured to be attached or mounted to the bumper of a vehicle or base member. The modular bumper attachment system may include a first attachment member and a second attachment member, each attachment member having a receiving member and an aperture defined by an outer wall that is configured to encompass the bumper of a vehicle. The system may also include one or more support members that are removably attached to the receiving member of each attachment member. The support member may have a first end and a second end, wherein the first end is removably attached to the receiving member. The second end of each support member may extend in a generally outward direction from the base member and include one or more connectors configured to removably attach a hammock, tent, awning, storage container, cooler, etc. to the support member.
US10173574B2	Motorcycle lift A lift system comprising a chassis having a frame. The frame including a first extension member and a second extension member opposite thereof. Each of the first extension member and the second extension member being extendable and coupled to the frame. A first scissor support is coupled to the first extension member. A second scissor support is coupled to the second extension member. The first and second scissor supports are configured rigid and extendable from each of the first and second extension members. A platform is coupled to each of the first and second scissor support. The platform is configured to rigidly support an object coupled thereto. A first actuator is coupled to the frame. The first actuator is configured to extend and retract the first and second extension members. A second actuator is coupled to the scissor lift and configured to move the platform.
US10173565B2	Vehicle seat and headrest with dynamic impact energy management system A vehicle seat includes a seatback with a back panel having a plurality of score lines defining a deflectable upper portion of the back panel. A headrest includes a housing with front and rear covers. The rear cover includes a plurality of score lines defining a deflectable lower portion of the rear cover. A trim ring is coupled between the deflectable upper portion of the seatback and the deflectable lower portion of the rear cover by one or more reinforcement brackets in assembly. The trim ring includes a plurality of notches disposed along a perimeter portion thereof. The notches of the trim ring cooperate to define deflection points of the trim ring along the perimeter thereof. The score lines and the notches of the vehicle seat provide for a dynamic impact energy management system for the seat at a head restraint thereof.
US10173564B2	Vehicle seat Lower end portions of an edge and another edge are fixed to a wire through pull-in cloths and a fixing member such that the pull-in cloths pull the lower end portions in toward the rear and into an opening (slit). This enables the edge and the another edge to be closed together in a state in which tension is applied to a front covering and a side covering. This enables the external appearance of a seatback to be preserved. Further, the edge and the another edge can be separated from each other, enabling a connector to be inserted into the opening from between the edge and the another edge, and the connector to be connected to an ISOFIX member. An inferior external appearance of the seatback can accordingly be suppressed while securing insertability of the connector.
US10173563B2	Seat having surface cover and peripheral cover with cooperative inclined piles The purpose of the present invention is to provide a seat that makes it possible to easily connect the end of a surface cover when assembling the surface cover and to achieve a secure connection. To this end, a seat (1) is provided with inclined piles (70, 80) on the end of the surface cover (4) and at a location that faces the end of the surface cover (4) on a cushion member (2) that forms a seat section, the inclined pile (80) of the cushion member (2) is inclined in a direction that is the opposite of the direction in which a load resulting from a seated person occurs, and the inclined pile (70) of the end of the surface cover (4) is inclined in the direction in which the load resulting from a seated person occurs.
US10173562B2	Airbag module-equipped seat, and method for mounting same An airbag module-equipped seat in which the periphery of an attachment portion of a guide member that guides a deployment direction of an airbag has a compact size and the guide member can be attached easily while maintaining satisfactory deployment performance of the airbag. This seat includes an airbag module attached to a side frame, a guide member that guides a deployment direction of the airbag module, and an attachment member for attaching the guide member to the side frame. The side frame has an attachment hole for the attachment member at a position different from a shaft portion for attaching the airbag module. The attachment member has a holding space in which an end of the guide member is held in a detachable manner, and is inserted into the attachment hole in a state in which the end of the guide member is held in the holding space.
US10173560B2	Isolation system for a seat The present invention is generally related to isolation systems for various seating configurations. The isolation system may comprise a first set of isolators positioned perpendicular to a second set of isolators. The positioning of the first and second sets of isolators may enable the isolation system to exhibit a radial stiffness of at least 350 lbf/inch. The improved radial stiffness of the isolation system may dampen and attenuate the transfer of energy (e.g., vibrations) to the seat, which may facilitate a smoother ride for an operator sitting in the seat.
US10173556B2	Seat for vehicles To provide a seat for vehicles in which a seat cushion escape mechanism can be space-saving, the seat having an escape mechanism to shift a seat cushion frame disposed on a base part from a seating posture to an escape posture with the frame placed forward of the base part includes: a support leg part having one end rotatably connected to the frame and the other end rotatably connected to the base part; a guide part to be engaged with the one end of the support leg part to guide the one end so as to lift the one end; a coil spring biasing the support leg part so as to have the one end guided by the guide part and flip up a portion connected with the frame; and a second coil spring which is provided at the other end and applies a biasing force so as to rotate the one end of the support leg part forward with the other end as a center.
US10173551B2	Control apparatus A control apparatus is provided in a rotary electric machine driving system that includes a rotary electric machine for a vehicle and a control unit that controls driving of the rotary electric machine. The apparatus includes a malfunction determination section determining whether or not a system malfunction that requires torque limitation has occurred, a to-be-avoided state determination section determining whether or not the vehicle is in a to-be-avoided state, a torque limitation section limiting an output torque outputted from the rotary electric machine to a limiting torque smaller than a command torque, when the system malfunction is determined to have occurred and the vehicle is not in the to-be-avoided state, and a torque limitation relaxation section permitting the output torque to be a limitation relaxation torque larger than the limiting torque, when the system malfunction is determined to have occurred and the vehicle is in the to-be-avoided state.
US10173547B1	Vehicle battery drainage avoidance A system for drainage avoidance includes an interface and a processor. The interface is configured to receive an indication to power on. A wake up voltage is increased after a power on signal is received. The processor is configured to perform a boot sequence, determine whether the boot sequence completed successfully, and in the event the boot sequence completed successfully, provide a reset indication to reset the wake up voltage.
US10173543B2	Charging system for electric vehicle and method for controlling charging of electric vehicle A charging system for an electric vehicle and a method for controlling charging of an electric vehicle are provided. The charging system comprises: a power battery (10); a charge-discharge socket (20); an external power supply device (1002); a charging connection device (1001); and an energy control device (1003), comprising: a three-level bidirectional DC-AC module (30); a charge-discharge control module (50); and a control module (60) configured to control the charge-discharge control module (50) according to a current working mode of the electric vehicle. The energy control device (1003) and the external power supply device (1002) communicate by transmitting a modulated PWM signal to each other via the charging connection device (1001), and the control module (60) controls the three-level bidirectional DC-AC module (30) and the charge-discharge control module (50) to charge the power battery (10) by the external power supply device (1002).
US10173534B2	Variable voltage converter control in vehicles A vehicle power system may include a gate driver configured to drive a traction gate and a generator gate corresponding to switches of a variable voltage controller such that the gates have alternating pulse width modulation ON periods. The gates may be driven in response to a throughput magnitude falling below a threshold. The gate driver may be further configured to drive the gates such that a duty cycle of one of the gates is zero in response to the throughput exceeding the threshold.
US10173533B1	Forced air battery charging system A forced-air battery charging system for a vehicle having an engine compartment includes a turbine assembly having a casing and a plurality of blades, the casing being positioned forwardly in the engine compartment for operably receiving ambient air as the vehicle travels forwardly and having an outlet expelling the ambient air. The plurality of blades are situated in the casing between the inlet and the outlet and are operable to rotate about an axis when impacted by the received ambient air in a direction askew to the axis. An electricity generator is operatively coupled to the plurality of blades. The system includes an air duct having walls that define a channel having proximal and distal ends, the proximal end being open and in communication with the casing outlet, the distal end being open through which the ambient air exits under the vehicle after passing through the air duct proximal end.
US10173532B2	System and method for controlling a vehicle A braking system for a vehicle includes an electric drive system associated with a first set of wheels. The electric drive system is configured to selectively provide electric motive power to the first set of wheels of the vehicle to propel the vehicle and electric retarding to slow the vehicle. The system further includes a friction brake system associated with a second set of wheels of the vehicle, and a controller for selectively actuating the electric drive system to operate in an electric retarding mode and for selectively actuating the friction brake system. The controller is configured to transfer retarding force from the first set of wheels to the second set of wheels, and/or to determine wheel speed signal accuracies, in either case to mitigate vehicle/wheel sliding or slipping.
US10173530B2	Power conversion system When a motor rotation speed is equal to or greater than a predetermined rotation speed when an automobile collision is detected or when power stops, a motor rotation speed reduction control is carried out by an inverter control unit, and when an inter-terminal voltage of a secondary smoothing capacitor drops below a predetermined voltage during the motor rotation speed reduction control, the motor rotation speed reduction control is stopped, whereby induction voltage caused by motor rotation is applied to the secondary smoothing capacitor, the inter-terminal voltage of the secondary smoothing capacitor is raised, and the motor rotation speed reduction control is carried out while keeping the inter-terminal voltage of the secondary smoothing capacitor within an operating voltage range of the inverter control unit.
US10173529B2	Driver assistance system and method for adapting the illumination of control elements in motor vehicles A method for controlling illumination of operational controls in a motor vehicle, using a passenger-compartment camera for photographing a driver, in which a visual perception capability of the driver is determined with the aid of the passenger-compartment camera, and in which the illumination of an operational control is adjusted as a function of the visual perception capability of the driver.
US10173527B2	Meter cluster seal A meter cluster includes a meter trim assembly and a combination meter. The meter trim assembly includes a meter cluster lid, a meter ring with a groove, and a seal portion having a connecting portion disposed within the groove to couple the seal portion to the meter ring. The combination meter has a transparent display cover disposed relative to the meter ring so as to form a gap between the meter ring and the transparent display cover. The seal portion is arranged to block transmission of light from a first portion of the meter cluster to a second portion of the meter cluster.
US10173526B2	System and method for locating and determining substance use Levels of substance use, location, and vital signs are remotely monitored for a subject. In one embodiment, the system includes a testing device and a communication device. The testing device obtains a breathalyzer sample from a test subject and determines a substance level. The communication device reports the substance level to a remote monitoring station. In addition, location and camera functions of the communication device can report additional information for verification and system integrity. In other embodiments, the system can be incorporated into an ankle bracelet for monitoring movement of an individual or into a vehicle system to prevent operation while impaired.
US10173523B2	Mouthpiece assembly of a fuel tank for vehicles with tight closing device A mouthpiece assembly of a fuel tank for vehicles has a box defining a recessed housing wherein a hole is obtained to access a duct leading to the fuel tank of the vehicle, a lid hinged to the box, and a closing device having a translating pin translatingly mounted, a cap disposed on the translating pin, and a push-push lock mechanism connected to the translating pin. The upper part of the translating pin has a plurality of longitudinal tabs that are elastically flexible outwards in such manner to deform the cap, forming a collar that protrudes outwards and is engaged tightly inside the seat of the lid of the fuel tank in order to hold the lid of the fuel tank in closed position.
US10173521B2	Fuel tank vapor valve assembly A tube extends through an attachment section and defines a vapor passageway. A housing is supported to the attachment section for movement between several positions relative to the attachment section. The housing defines a float chamber below the tube. A valve seat portion is located within the float chamber and has an engagement part, a sleeve part and a seat surface. The engagement part is connected to the housing. The sleeve part telescopically engages the tube and is movable along the tube with the housing. The valve seat portion defines a central bore open to the vapor passageway and the seat surface. The float moves within the float chamber. When to fluid enters the float chamber the float floats up against the seat surface closing off the central bore and the vapor passageway. In the absence of fluid the float moves downward exposing the seat surface.
US10173520B1	Fuel cap detection system A fuel cap detection system includes a charcoal canister, a notification system, and an electronic controller. The charcoal canister is connected to a fuel tank of a vehicle, the charcoal canister includes a vent valve. The notification system is configured to notify a user when a fuel cap is incorrectly positioned. The electronic controller is configured to perform a leak detection test on the fuel tank by activating the vent valve in the charcoal canister to determine whether the fuel cap is positioned incorrectly, and determine an intent of the user to reposition the fuel cap while the notification system notifies the user that the fuel cap is incorrectly positioned.
US10173514B2	Planetary axis transfer gearbox A motor vehicle planetary axis transfer gearbox system includes a connective housing connecting an engine to a transmission of a motor vehicle with the transmission being positioned forward of the engine. An axis of an engine output shaft is oriented substantially parallel to an axis of a transmission input shaft. Both the axis of the engine output shaft and the axis of the transmission input shaft are oriented substantially perpendicular to a central axis of the motor vehicle. A planetary gear set is connected to one of the engine output shaft or the transmission input shaft acting to reverse a direction of rotation of either the engine output shaft or the transmission input shaft to match a direction of rotation of both the engine output shaft and the transmission input shaft. A drive chain connects the engine output shaft to the transmission input shaft.
US10173511B2	Battery mounting structure for vehicle A battery mounting structure is provided to prevent water intrusion into a clearance between a battery pack and a floor panel of a vehicle. The battery mounting structure comprises: frame members extending longitudinally on both sides of the vehicle; a floor panel disposed between the frame members; and a battery pack situated underneath the floor panel. A sealing member is interposed between a periphery of the battery pack and a portion extending from a member opposed to the battery pack, and a drain hole is formed in the sealing member to connect an inner side and an outer side of the sealing member.
US10173510B2	Active vehicle pillar arrangement for selective wind noise, wind throb, snow buildup and moisture control An apparatus is for use with a pillar adjacent to a vehicle window, such as a windshield. The apparatus includes a molding for positioning adjacent to the pillar, the molding forming a channel in a deployed condition for receiving moisture from the vehicle windshield, or for reducing the effects of wind throb when a single vehicle window is open. An actuator may be associated with the molding for activating a non-deployed condition of the molding for reducing the effects of wind noise.
US10173508B2	Top of a convertible vehicle comprising panel bows A top of a convertible vehicle is proposed, comprising a top cover and a top linkage which can be displaced between a closed position, in which a vehicle interior is covered, and a storage position, in which the vehicle interior is open toward the top, and which has a linkage arrangement on both sides with respect to a vertical longitudinal center plane of the top, each linkage arrangement comprising two main links, which are pivotably mounted on a main bearing fixed to the vehicle and one of which is driven by means of a main drive. Panel bows extend between the bilaterally arranged linkage arrangements, a first one of said panel bows being a front bow, a second one being a front center bow, a third one being a rear center bow and a fourth one being a rear window bow. In the storage position, the rear center bow is arranged below the rear window bow.
US10173503B2	Open roof construction for a vehicle and rollo assembly for use therein An open roof construction for a vehicle comprises a rollo assembly. The rollo assembly comprises a rollo screen and a winding shaft for the rollo screen which is rotatable around a stationary axis of rotation. The rollo screen firstly extends in a first direction, next around a reversal member and finally back in an opposite second direction and ends at a rollo screen edge which is attached to a stationary member. The rollo screen has two longitudinal edges which, when the rollo screen is wound off, are brought into engagement with holding members. The longitudinal edges of the rollo screen each comprise a hooking member insertable into a holding groove and hook behind a narrow entrance thereof. A reversal member is provided with a device acting on at least one of the hooking member and holding groove to enable the hooking member to enter and exit the holding groove.
US10173500B2	Anti-glare device and method for automobiles An anti-glare device for reducing night-time road glare includes an anti-glare panel for attenuating and/or filtering light traveling from a source of glare through the panel to a driver's eyes. The anti-glare panel is secured to a sun visor of an automobile via an attachment mechanism comprising an elastic member, which compresses around the sun visor. The anti-glare panel attaches to the elastic member via attachment arms of the anti-glare panel that are folded over and secured, forming loops through which the elastic member is threaded. The attachment mechanism can further comprise a secondary elastic member for holding the anti-glare panel in an inactive position when the device is not being used. Additionally, the horizontal width of the anti-glare panel can decrease over the panel's vertical length, forming a recess at the panel's bottom corner for allowing natural visibility of a center line and/or lane markings of the road.
US10173499B1	Mechanism for sun visor extension A vehicle visor includes a visor body having an inner cavity with first and second channels disposed therein. A blade is slideably mounted to the first and second channels between extended and retracted positions by first and second rails of the blade that are slideably received in the first and second channels of the visor body. An adjustment knob is mounted on the visor body and includes a toothed outer perimeter that gearingly engages a toothed track disposed on the blade within the inner cavity. The adjustment knob further includes an exposed portion that is disposed outside of the inner cavity and accessible to a user for incremental rotation resulting in deployment or retraction of the blade.
US10173497B2	Auxiliary vehicle HVAC system for efficient multi-zone spot cooling A vehicle air-conditioning system includes a primary loop coupled to an air-conditioner that cools a refrigerant in the primary cooling loop for delivery to a primary heat exchanger, a secondary cooling loop in communication with the primary heat exchanger, wherein cooling from the refrigerant is transferred to a coolant in the secondary cooling loop and a secondary heat exchanger for transferring cooling from the coolant to air delivered to a rear of a vehicular passenger cabin.
US10173495B2	Modular HVAC system for engine-on and engine-off operation An auxiliary HVAC system includes an engine-on module configured to provide cooling or heating during an engine-on mode and an engine-off module connected to the engine-on module and configured to provide cooling or heating during an engine-off mode.
US10173490B2	Dynamic damper control device A controller includes a target frequency determining unit, first and second acceleration sensors, and a predetermined variable calculator. The target frequency determining unit determines a target frequency from a vibration state of a vibration source. The first acceleration sensor obtains a first acceleration of a mass member. The second acceleration sensor obtains a second acceleration of a vibration controlled member. The predetermined variable calculator calculates a predetermined variable of a transfer function of the first acceleration with respect to the second acceleration at the target frequency. If the predetermined variable is a numeric value other than 0, the controller changes a magnetic force generated in an electromagnet.
US10173489B2	Vehicle suspension control systems and devices, and related methods A method of controlling a suspension system of a vehicle includes identifying an amplitude and a frequency of at least one harmonic event in a topology of a surface to be traversed by the vehicle, and, with a controller, altering at least one response characteristic of at least one adjustable component of the suspension system based on at least one of the amplitude and frequency of the harmonic event. Systems and methods relate to controlling vehicle suspension systems.
US10173488B2	Air spring hanging piston bearing An air spring assembly for a vehicle having a damper body which is decoupled from a piston, allowing the damper to rotate freely without inducing torsion into the piston. The air spring assembly includes a damper body, and a decoupling mechanism connected to the damper body, where a portion of the decoupling mechanism surrounds the damper body. A piston is connected to the decoupling mechanism such that the decoupling mechanism allows for rotation of the damper body relative to the piston, preventing torsion from being transferred from the damper body to the piston. The decoupling mechanism also includes a rotatable machine element, such as a bearing, surrounding the damper body, and the bearing is adjacent the cup portion such that the rotatable machine element facilitates relative rotation between the damper body and the spring cup portion to limit torsion applied to the piston from the damper body.
US10173477B2	Pneumatic tire A tire includes a pair of beads, a carcass, chafers, an insulation, and cushion layers. Each bead includes a core positioned inward of the bead in a radial direction. At an inside of the core in the radial direction, the insulation is laminated on the chafers so as to be located outward of the chafers in the radial direction. Each cushion layer is laminated on the insulation so as to be located outward of the insulation in the radial direction. The insulation and the cushion layer are formed from respective crosslinked rubbers different from each other. A compressive elastic modulus Eα* of the crosslinked rubber of the cushion layer is smaller than a compressive elastic modulus Eβ* of the crosslinked rubber of the insulation.
US10173473B2	Pneumatic motorcycle tire A pneumatic motorcycle tire includes a tread portion provided in each half tread region with a unit pattern repeatedly arranged in the tire circumferential direction to form a unidirectional tread pattern. The unit pattern includes a first groove extending axially outwardly from a vicinity of the tire equator, while inclining to the opposite direction to the intended tire rotational direction; a second groove disposed on the heel-side in the tire rotational direction of the first groove and extending along the first groove; a third groove disposed on the heel-side of the second groove and extending along the second groove; a fourth groove disposed on the heel-side of the third groove and extending along the third groove; and a narrow groove extending from an axially inner end of the first groove to an axially inner end of the fourth groove, while inclining to the intended tire rotational direction.
US10173471B2	Pneumatic tire with cylindrical metal annular structure and method of manufacturing same A pneumatic tire includes: an annular structure that is cylindrical and metal where at least an outer side surface in the radial direction is a rough surface; a tread rubber layer that will become a tread portion provided along a circumferential direction of the annular structure on an outer side of the annular structure; and a carcass portion including fibers covered with rubber, provided on at least both sides in a direction parallel to a center axis of the cylindrical structure including the annular structure and the tread rubber layer.
US10173469B2	Polymer films There is provided a polymer film which includes: a base film layer including a polyamide-based resin having a particular relative viscosity and a copolymer including a polyamide-based segment and a polyether-based segment having a specific content; and an adhesive layer formed on at least one side of the base film layer, wherein a ratio of the melt viscosity of the copolymer to the melt viscosity of the polyamide resin is 0.65 to 1.2 at a shear rate of 1000 s−1 and a temperature of 260° C.
US10173468B2	Reinforced product comprising a composition with a low sulfur content and tire comprising said reinforced product A reinforced product, which can be used especially for reinforcing a finished rubber article, comprises one or more textile or metallic reinforcing thread(s), said thread(s) being covered with a sheath comprising a thermoplastic polymer composition, the sheathed thread(s) being themselves embedded in a rubber composition referred to as coating rubber, characterized in that this coating rubber is a composition based on at least one diene elastomer, silica as predominant reinforcing filler, and a sulfur-based vulcanization system, in which the ratio of the amounts, in phr (parts by weight per hundred parts by weight of elastomer), of sulfur and of reinforcing filler, is less than 0.08.
US10173463B2	Motorized wheel with suspension A wheel comprises a rim, a hub and a suspension unit. The wheel incorporates or is connectable to a torque source capable of producing torques up to a maximal torque for rotating the wheel around a rotation-axis. In this invention, the suspension unit includes at least one structural member, provided at least partially between the rim and the hub, configured to change in size and/or shape, relative to a nominal size and/or shape thereof, during displacements and/or rotations of the hub relative to a center point of the rim. The suspension unit also includes at least one motion resisting component adapted to retain the structural member at the nominal size and/or shape thereof under torques smaller than the maximal torque.
US10173462B2	Rim assembly The invention relates to a rim assembly for a vehicle having a rim having an axial inside facing the vehicle and an axial outside facing away from the vehicle, a rim flange designed on the axial outside of the rim, and a first groove designed in the rim. The first groove is arranged in the rim flange or axially outside of the rim flange, and a disc-shaped cover, which covers the axial outside of the rim. The radially outer edge of the cover inserts in the first groove and a first elastic element in the first groove clamps the radial outside edge.
US10173461B2	Wheel spider A wheel with a rim as well as a wheel spider, where the wheel spider has a hub and spokes. The wheel includes spokes including one or more linearly stretched textile strands as reinforcement material of a fiber composite and each linearly stretched textile strand runs at least once from the rim to the hub and back without interruption and thus forms at least one spoke. The textile strands are connected in a positive-locking manner and/or in substance with the hub and the rim. A process is provided for the manufacture of the wheel.
US10173459B2	Surgical marker A marking instrument having a plurality of removable writing nibs serially aligned so that an operator can remove a spent or fluid-affected writing nib and, thereby, access a fresh writing tip.
US10173458B2	Lever for a ring binder mechanism A ring mechanism for retaining loose-leaf pages includes a housing and ring members for holding loose-leaf pages that are moveable relative to the housing between an open and closed position. An actuation system moves the ring members and includes hinge plates pivotally mounted on the housing and an actuator actuating pivoting movement of the hinge plates. A travel bar of the actuation system is moveable by the actuator between a locked position blocking pivoting movement of the hinge plates and an unlocked position allowing pivoting movement of the hinge plates. The actuation system is adapted to deform while moving the travel bar from the locked position toward the unlocked position to delay the pivoting motion of the hinge plates from the movement of the actuator.
US10173453B2	Optical security device An improved form of optical security device for use in the protection of documents and articles of value from counterfeit and to verify authenticity is provided. The inventive device, which is made up of an optionally embedded array of icon focusing elements, at least one grayscale in-plane image, and a plurality of coextensive control patterns of icons contained on or within the in-plane image, each control pattern being mapped to areas of the grayscale in-plane image having a range of grayscale levels, provides enhanced design capability, improved visual impact, and greater resistance to manufacturing variations.
US10173452B2	Information recording media and method for printing on information storage media To provide an information storage medium and a method for printing on the information storage medium that can improve a quality of printing on a laser coloring layer in a lower than a functional film layer. A card 1 includes: a base material 11; a laser coloring layer 12 that is laminated upper Z2 than the base material 11 and produces color by laser irradiation; a transparent layer 13 that is laminated upper Z2 than the laser coloring layer 12 and is translucent; a Lippmann hologram layer 14 that is laminated upper Z2 than the transparent layer 13 and is translucent; and a transparent layer 15 that is laminated upper than the Lippmann hologram layer and is translucent.
US10173448B2	Ribbon cassette including spring member for applying tension to ink ribbon A ribbon cassette includes: a cassette case having first and second holes; an ink ribbon; first and second spools; an engaging part; and a spring member. The ink ribbon has one end wound on the first spool, and another end connected to a first end portion of the second spool. The spring member is wound around a second portion of the second spool. The spring member includes: a winding part wound around the second portion; and an extension part extending from the winding part and engaged with the engaging part. The winding part is wound in a direction opposite to a take-up direction of the second spool. A second draw-out load applied to the ink ribbon being pulled from the second spool through the second hole is smaller than a first draw-out load applied to the ink ribbon being pulled from the first spool through the first hole.
US10173447B2	Printer with movable carriage A printer having a carriage (10) movable along a guide beam (12) in a main scanning direction (y), and a number of print heads (14) mounted on the carriage (10), each print head having a plurality of printing elements (16), wherein the carriage (10) has at least two sub-carriages (38) each of which carries at least one of the print heads (14) and is independently guided at the guide beam (12), and the sub-carriages (38) are coupled for joint movement in the main scanning direction (y) but are movable relative to one another in a sub-scanning direction (x) normal to the main scanning direction (y).
US10173446B2	Printer According to one embodiment, a printer includes a housing that has an outlet, a drawer unit, first, second and third print medium support units and a printing unit. The drawer unit slides in the outlet between an open position and a closed position. The first supporting unit is disposed in the drawer unit and supports a roll of printable media when the drawer unit is in the open position so that an outer surface of the roll of printable media does not extend above the height of the outlet. The second supporting unit is disposed in the housing and rotatably supports the roll of printable media when the drawer unit is in the closed position so that a portion of the outer surface of the roll of printable media extends above the height of the outlet. The printing unit prints on printable media fed from the roll of printable media.
US10173445B2	Sheet transporting apparatus and image forming system A sheet transporting apparatus is provided, including a transport mechanism provided with a roller, a motor, a controller, and a measuring input unit, wherein a transport route has a curved area for inverting the sheet, and the controller is constructed such that the control on the motor is executed by a closed loop control system by using a measured value of an control output at an initial stage of the transport of a sheet from a tray, and the control on the motor is switched from the control performed by the closed loop control system to control performed by an open loop control system on condition that a preset phenomenon arises after the sheet is taken out of the tray.
US10173444B2	Printer and method of printing A printer includes a conveying device that conveys a printing medium and a cutting device that makes a trim cut in at least one of a plurality of corners of a region where a printed material has been printed. The conveying device conveys the printing medium to the cutting device before the cut is made.
US10173436B2	Liquid circulation device and liquid discharge apparatus There is provided a liquid circulation apparatus for circulating liquid through a plurality of discharge heads that includes discharge nozzles. The liquid circulation apparatus includes a liquid circulating channel to circulate the liquid via the plurality of discharge heads, a first manifold connected to each supply port of the plurality of discharge heads, a second manifold connected to each discharge port of the plurality of discharge heads, a discharging channel to discharge the liquid in the second manifold, and a bubble-discharging channel separate from the discharging channel, to discharge bubbles in the second manifold.
US10173435B2	Fluid ejection device including recirculation system A fluid ejection device including, at least, one recirculation system is disclosed. Such recirculation system contains, at least, one drop generator, recirculation channels that include an inlet channel, an outlet channel and a connection channel and a fluid feedhole that communicates with the drop generator via the inlet channel and the outlet channel of the recirculation channel. The recirculation channels can be asymmetrical with reference to the drop generator.
US10173433B2	Tank and liquid consuming apparatus including the same There is provided a tank including: first and second chambers; a liquid inlet port; a first communicating port; a communicating channel; a second communicating port; an atmosphere open port; a gas-liquid separating membrane provided in the communicating channel; and a liquid outflow port. In a state that a first wall constructing a first end of the tank in a usable posture constructs an upper portion of the tank and that a second wall constructing a second end, of the tank in the usable posture, which is away in a horizontal direction from the first end constructs a lower portion of the tank and under a condition that a maximum amount, of the liquid, storable in the tank in the usable posture, is stored in the first and second chambers, the gas-liquid separating membrane is located at a position above the liquid surface of the maximum amount of the liquid.
US10173432B2	Printer A decrease in the capacity of an ink tank can be easily avoided while downsizing a printer. A printer includes a printing head, an ink tank, a carriage provided with the printing head movable back and forth, and a medium conveyance device that conveys a printing medium on a conveyance path intersecting the carriage moving direction. An axis line along the carriage moving direction is an X axis and an axis line orthogonal to the X axis is a Y axis, an axis line orthogonal to the X and Y axises is defined as a Z axis. When viewed along the Z axis, the ink tank is located in a region outside a movable region of the carriage along the Y axis, and is arranged so as to extend across a region outside the conveyance path along the X axis and a region that is overlapped with the conveyance path.
US10173431B2	Liquid containing member A liquid containing member that can supply a liquid having a uniform concentration of a precipitating component to a liquid ejecting portion is provided. A liquid containing member includes: a liquid containing portion that can contain ink; a liquid supply port for supplying the ink contained in the liquid containing portion to a liquid ejection head; and a communication channel that is in communication with the liquid containing portion and the liquid supply port. The communication channel has a first end that is positioned at a lower end on the gravity direction side in the liquid containing portion and can suck the ink, and a second end that is positioned closer to the anti-gravity direction side than the first end is, and can suck the ink, in an in-use state in which the ink is supplied from the liquid supply port to the liquid ejection head.
US10173419B2	Printing apparatus and printing method The printing apparatus is provided with a transport mechanism section that transports work, a printing mechanism section that has nozzles, which carry out printing by discharging an ink, as liquid droplets, onto the work transported by the transport mechanism section, and an adjustment section that adjusts a volume per single droplet of the ink discharged from the nozzles on the basis of a separation distance between the nozzles and the work, which is positioned directly below the nozzles.
US10173418B2	Transfer data generator, printing device, and transfer data creation method A transfer data generator creates transfer data that suppresses an increase in radiation noise generated when the transfer data is transferred to an ink head. The transfer data generator creates transfer data including transfer printing image data to be transferred to the ink head, and a transfer clock signal. The transfer data generator includes a clock signal creation processor that generates a pulse period of at least one pulse of a plurality of pulses of the reference clock signal different from each of pulse periods of the other pulses to generate the transfer clock signal from the reference clock signal, and a printing image data creation processor that adjusts the reference printing image data so as to correspond to the transfer clock signal to generate transfer printing image data.
US10173416B2	Droplet discharge apparatus, control device, and control method A printing apparatus (droplet discharge apparatus) includes a discharge portion that has a nozzle discharging ink to a medium and a control device that allows the discharge portion to discharge the ink depending on execution of a print job defining a mode for discharging the ink to the medium. Before the print job is executed, the control device calculates a discharge amount fluctuation which is a fluctuation in a discharge amount of liquid per unit time by the discharge portion based on the print job and determines whether or not maintenance for recovering ink discharge performance of the discharge portion is required at the time of executing the print job based on the discharge amount fluctuation.
US10173414B2	Customizable apparatus and method for transporting and depositing fluids A system for depositing a fluid on a substrate is disclosed. The system can include a sleeve having a sleeve exit and an inner region and a rotating roll disposed within the inner region. A vascular network can be disposed within the rotating roll, the vascular network being configured for transporting the fluid in predetermined paths from the interior region to the exterior surface through a substantially radial path, the substantially radial path ending at an exit point of a fluid exit, wherein the exit point is associated with a sleeve exit.
US10173409B2	Rapid nozzle cooling for additive manufacturing Systems, devices, and methods according to the present disclosure are configured for use in additive manufacturing. Systems for additive manufacturing can include stand-alone manufacturing units, a series of units on an assembly line, or a high-capacity system with workflow automation features including a conveyor for transporting parts to or from a build area, or a robotic arm for transporting parts or adjusting a system component. An additive manufacturing system (100) can include a flow regulator (130) to change a temperature of a thermoplastic material at or in a tip (150) of a material extrusion nozzle cartridge (171), such as to enable or inhibit flow of the thermoplastic material from the tip. The flow regulator can be configured to provide a specified gas or liquid at a specified temperature, velocity, or volume.
US10173404B2	Synthetic resin skin material and method of manufacturing synthetic resin skin material A synthetic resin skin material includes, on one side of a base material 12, an adhesive layer 14, a skin layer 16, and a surface processing layer 18 in this order from the base material 12, the adhesive layer 14 and the skin layer 16 containing a polyurethane urea resin having a number average molecular weight of from 35,000 to 100,000.
US10173398B2	Method of making a composite non-planar door skin A method of forming a composite article is disclosed that involves providing a press having first and second platens, a cellulosic fiber substrate having a first thickness, and a layer of material such as a wood veneer, foil, or non-creped paper, where the layer of material has a thickness less than the thickness of the cellulosic fiber substrate. A layer of bonding material is placed onto the cellulosic fiber substrate or the layer of material, and the layer of material is placed onto the cellulosic fiber substrate so that the bonding material is between the layer of material and the cellulosic fiber substrate. The cellulosic fiber substrate and layer of material are placed between the first and second platens, and at least one of the first and second platens is moved toward the other of the first and second platens to deform the cellulosic fiber substrate and layer of material into a predetermined configuration while bonding the layer of material to the cellulosic fiber substrate without cracking or wrinkling the layer of material.
US10173397B2	Thermoplastic resin film and laminated glass There is provided a thermoplastic resin film which is high in tear resistance. The thermoplastic resin film according to the present invention is provided with a plurality of first thermoplastic resin layers each containing a thermoplastic resin and a plurality of second thermoplastic resin layers each containing a thermoplastic resin, and has a multilayer structure in which the first and second thermoplastic resin layers are laminated in the thickness direction, the number of laminations in total of the first and second thermoplastic resin layers in the thickness direction is greater than or equal to 5, the ratio of the total thickness of the first thermoplastic resin layers to the total thickness of the second thermoplastic resin layers is greater than 1, the tensile modulus of elasticity of the respective first thermoplastic resin layers is less than or equal to 30 MPa, and the tensile modulus of elasticity of the respective first thermoplastic resin layers is greater than or equal to 280 MPa.
US10173392B2	Process for producing article from layered hardcoat object, and article formed from layered hardcoat object including poly(meth)acrylimide-based resin layer The present invention pertains to a process for producing an article from a layered hard coat object including a hard coat layer and a transparent-resin film layer in this order from the outermost layer side, the process comprising: a step (A) in which a pressure-sensitive adhesive layer of a support having the pressure-sensitive adhesive layer on at least one surface thereof is temporarily applied to at least one surface of the layered hard coat object to obtain a temporarily support-bearing layered hard coat object; a step (B) in which at least one processing method selected from the group consisting of router processing, water-jet processing, laser processing, and punching is applied to the temporarily support-bearing layered hard coat object to cut the temporarily support-bearing layered hard coat object into a given shape, thereby obtaining a temporarily support-bearing cut article; and a step (C) in which at least one kind of energy selected from the group consisting of heat and actinic rays is applied to the temporarily support-bearing cut article to reduce the strength of tackiness between the support and the article to 2 N/2.5 cm or less.
US10173391B2	Pad comprising an extruded mesh and method of making thereof A structure for use in a compressible resilient pad. The structure contains both axially elastomeric strands and relatively inelastic strands co-extruded in various patterns. The structure has a high degree of both compressibility under an applied normal load and excellent recovery (resiliency or spring back) upon removal of that load.
US10173389B2	Carbon dioxide shielded natural gas line and method of using thereof A natural gas line comprises a concentric pipe having an inner natural gas pipe and an outer carbon dioxide pipe surrounding the inner pipe. Carbon dioxide in the outer pipe comprises a shield which prevents or decreases natural gas leakage to the atmosphere. The carbon dioxide may be supplied from an exhaust of a fuel cell system, such as carbon dioxide separated from the fuel exhaust of a fuel cell system by a carbon dioxide separator. The natural gas may flow from a natural gas field to the fuel cell system via the inner pipe while the carbon dioxide may flow from the fuel cell system to the natural gas field via the outer pipe. The carbon dioxide may be sequestered in the empty space underground in natural gas field created by the extraction of the natural gas.
US10173385B2	Electric press, bend-point detection method, and program A detection unit for detecting a data row of a press position and a load at the press position; an input/storage unit for inputting and storing a value serving as a reference for determining a bend point in a relation between the press position and the load at the press position; a data-row calculation unit for calculating a data row of a press position and a load at a constant distance interval based on the data row of the press position and the load detected; a slope calculation unit for calculating a slope of the load based on the press position and the load at the press position detected; and a bend-point determination unit for determining a point, at which the calculated slope of the load exceeds the value serving as the reference for determining the bend point, as the bend point are provided.
US10173383B2	Method for controlling the thickness of a continuous elongated element made of elastomeric material in a process for building tyres A method for controlling the thickness of a continuous elongated element made of elastomeric material, applied according to coils wound on a forming support, includes: advancing a head end of the continuous elongated element toward the forming support; subjecting, during the advancement, the continuous elongated element to a first stretching with a first stretch coefficient before applying on the forming support; and subjecting, during the advancement, the continuous elongated element to a second stretching with a second stretch coefficient during the application on the forming support. During the first stretching, a span of the continuous elongated element adjacent to the head end is stretched with a supplementary stretch coefficient greater than the first stretch coefficient, in a manner so as to confer, also to the span adjacent to the head end, a stretch and a section similar or substantially equivalent to those of the rest of the continuous elongated element.
US10173379B2	Device for heating a mold A heating device to heat a molding face, particularly a large molding face. The heating device includes a metal sheet having a ferromagnetic layer, and a part formed into a shape that defines the molding face and a forming plane. A base of the heating device supports the metal sheet. An inductor of the heating device provides the induction heating of the metal sheet.
US10173376B2	Apparatus for laminating fiber tow and manufacturing method of product using the same An apparatus for laminating a fiber tow is provided. The apparatus includes a supply unit that supplies a fiber tow impregnated with resin. A laminating unit is configured to move along a surface of a lamination object and has a shock-absorption element to laminate a fiber tow supplied from the supply unit on a surface of the lamination object.
US10173372B2	Method for forming heat-shielding film and heat-shielding film structure A second heat-shielding film 20 produced by anodizing treatment of both surfaces of pure Al foil with an Al purity equal to or larger than 99.0% is disposed on a surface of a first heat-shielding film 12 that is formed by anodizing treatment of a surface of a combustion chamber configuring component 10 formed from an Al alloy (Al purity of less than 99.0%) as a based material. A heat resistant adhesive is poured from between these heat-shielding films, and the heat resistant adhesive is heated and cured (an intermediate layer 22). Since the second heat-shielding film has low surface roughness Ra of an average of approximately 1.0 μm even in an unpolished state, polishing or the like for the film with an objective of smoothing after bonding of the second heat-shielding film can be omitted. Further, the heat-shielding film structure with a smoothed surface can be provided.
US10173371B1	System and method for forming a bonded joint A method and apparatus for forming a bonded joint on a composite structure is presented. An apparatus carrying a first workpiece is positioned relative to a second workpiece. A vacuum is applied to the first workpiece and a portion of the second workpiece. A bladder on a first surface of a housing of the apparatus is deflated. Deflating the bladder positions the first workpiece such that adhesive having a desired thickness is positioned between the first workpiece and the second workpiece. The adhesive positioned between the first workpiece and the second workpiece is cured.
US10173369B2	Multi-layer product with sealing areas of varying temperature An article of manufacture that has at least three layers of heat sealable material. There is at least one first heat seal between at least two of the layers in a first area effected at a first temperature. There is also at least one second heat seal between at least two more layers, where at least one of these two layers is distinct from the at least two layers joined by the first heat seal, in a second area effected at a second temperature, where the second temperature is different than the first temperature, thereby allowing for heat sealing of discrete areas of the article in discrete steps.
US10173366B2	Method for using an optical sensor array to monitor color fidelity in objects produced by a three-dimensional object printer A three-dimensional object printer generates image data of an object being formed in the printer with an optical sensor array and identifies the color of an upper surface of the object. The controller compares the identified color to a predetermined range about an expected color for the upper surface and operates ejectors to eject material of a color different than the identified color in response to the identified color being outside of the predetermined range.
US10173365B2	Spray charging and discharging system for polymer spray deposition device The disclosed spray deposition systems and methods use spray charging and discharging techniques to assist with digital deposition of spray droplets on a substrate. For example, the disclosed systems and methods have a charging system that generates spray droplets from a spray generator and charges the droplets. Focusing electrodes help to collimate the droplets into a tight droplet stream and, optionally, steering electrodes help direct the tight droplet stream. A charge removal system neutralizes or removes the charge from the droplets, either during the deposition of the droplets on a substrate or after the droplets have been deposited on a substrate.
US10173362B2	Forming apparatus and method and object thus made A method for making objects by forming a thermoformable sheet material includes forming the objects by interaction of a die assembly and a forming assembly. The method further includes, compressing and crushing a first portion of the sheet material by a crushing punch device before forming the objects and maintaining the first portion crushed during the forming operation to reduce the thickness thereof and to orientate chains of molecules that compose a structure of the sheet material at the first portion, in order to weaken the structure and the first portion. The first portion is thus easily perforable, tearable and breakable.
US10173360B2	Hollow container manufacturing method and manufacturing apparatus A hollow container manufacturing method comprises: an injection molding step of forming a preform having a neck portion and a barrel portion, at least a part of the barrel portion being solid, by injection molding; an intermediate product formation step of inserting a boring rod 134 from the neck portion side into the barrel portion 23 to form a space part of at least a predetermined depth in the barrel portion, thereby converting the preform into an intermediate molded product; and a final blow molding step of blow-molding the intermediate molded product within a final blow mold to form a hollow container which is a final molded product.
US10173357B2	Poly(ethylene glycol) cross-linking of soft materials to tailor viscoelastic properties for bioprinting Extrudable hydrogel compositions for printing 3D objects, such as cell growth scaffolds, are provided. Also provided are methods for making the crosslinked hydrogel compositions and the printed objects and methods for culturing cells using the cell growth scaffolds. The hydrogel precursor solutions are aqueous solutions comprising a biocompatible polymer, functionalized polyethylene glycol as a crosslinker and, optionally, cells and/or bioactive factors.
US10173356B2	Injection molding flow control apparatus and method An apparatus for controlling the rate of flow of a fluid mold material comprising: a manifold, an actuator interconnected to a valve pin, a position sensor that senses position of the valve pin, a controller that controls movement of the actuator according to instructions that instruct the actuator to drive the valve pin upstream at one or more selected intermediate velocities in response to receipt by the controller of a signal from the position sensor that the valve pin is disposed in the one or more intermediate upstream gate open positions.
US10173353B2	Biocomposite and/or biomaterial with sunflower seed shells/husks The invention relates to a biomaterial and/or a biocomposite based on sunflower seed shells/husks. According to the invention, it is proposed that sunflower seed shells/husks are used instead of wood, bamboo or other wood-like fiber products as the original material for the biocomposite products and are used for the production of such products in order to improve the previous biomaterials, and in particular also to design said materials for improved cost efficiency and to improve their material properties.
US10173343B2	Slurry distribution system with vibration isolation A cementitious slurry mixing and dispensing system includes a slurry mixer that agitates and forms aqueous cementitious slurry, a discharge conduit in communication with the mixer and forming an interior surface defining a slurry flow path to convey the slurry therethrough to an outlet, a distribution mat disposed proximally to the outlet, a vibrating plate supporting the distribution mat, an overhead bracing system from which the vibrating plate is suspended, and a plurality of support members coupled between the overhead bracing system and the vibrating plate. The vibrating plate is adapted to impart vibrational forces on the distribution mat to promote movement of the aqueous slurry. Each support member includes a rod, a hollow coupling member, and at least one resilient bushing assembly adapted to dampen the vibrational forces exerted by the vibrating plate, thereby isolating the rod and the overhead bracing system from the vibrational forces.
US10173342B2	Arrangement and method for curing concrete products An arrangement for curing concrete products, which contains a curing chamber having several curing cells arranged in at least one column, in which curing cells are located on a vertical stack. The curing cells are formed to curing cell groups, in which one curing cell group contains at least one curing cell, advantageously 2-4 curing cells, and wherein the curing cell group is insulated in respect of other curing cell groups of the curing chamber. A method for curing concrete products in a curing chamber, which includes several curing cells arranged in at least one column, in which the curing cells are located on a vertical stack. In the method the moisture level of curing cells is controlled such that in the curing cells the temperature is desired.
US10173329B2	Method and robot cell for handling stacks of flexible substrates The invention concerns a method of handling stacks of flexible substrates (14) by means of a gripper (8) as well as a robot cell (1) for carrying out the method. The gripper (8) is arranged on an arm (6) of a robot (2) and has a lower finger and a corresponding upper finger. The method comprises the steps of inserting said lower finger below a bottom substrate (14) of a stack resting on a base and said upper finger above a top substrate (14) of the stack, and gripping the stack by clamping it between said lower and upper finger. Then by means of the gripper (8) starting at a stack front the entire stack is lifted into a pendent state and moved to a support (16). There the stack is lowered such that a stack rear, which is opposite to said stack front, comes into contact with the support (16). Finally the entire stack is laid out on the support (16) with said bottom substrate (14) up by further lowering and while horizontally displacing the gripper (8) in a bottom-to-top substrate direction before letting the gripper (8) release the stack.
US10173322B2	Multi-axis robotic arm and adjusting method thereof An adjusting method is implemented by a control system and is used to adjust a multi-axis robotic arm including a plurality of motors. The adjusting method includes following operations. A decay rate of each motor is analyzed by the control system. When the decay rate of one of the motors exceeds a corresponding first threshold, a residual value of the one of the motors is further analyzed by the control system. When the residual value exceeds a first default value, an output capacity of at least one of the motors is adjusted by the control system.
US10173320B1	Robot task optimization based on historical task and location correlated durations Methods, apparatus, systems, and computer-readable media are provided for optimizing robot-implemented tasks based at least in part on historical task and location correlated duration data collected from one or more robots. Historical task and location correlated duration data may, in some implementations, include durations of different tasks performed in different locations by one or more robots in one or more particular environments, and knowledge of such durations may be used to optimize tasks performed by the same or different robots in the future.
US10173317B2	Multi-articulated manipulator A multi-articulated manipulator composed of more than one hollow outer shell, joints to connect the outer shells to each other, a grasping member fastened for rotating movement with respect to the proximal outer shell, a claw transmission shaft to actuate the grasping member to rotate and an outer shell power transmission shaft to actuate the outer shells in to rotate independently from each other. The claw transmission shaft and the outer shell power transmission shaft respectively are composed of universal joints capable of rotating force and transmitting torque.
US10173312B2	Architectural covering with repositionable handle assembly An architectural covering, comprising a rail and a repositionable handle assembly. The rail has a groove. The assembly comprises a handle with a hole for receiving a fastener, and a fastener receiving member. The fastener receiving member is free to slide along the groove when in an undamped state. A fastener is also provided for mechanically connecting the handle to the fastener receiving member and for clamping the handle and the fastener receiving member in a desired position on the rail.
US10173311B2	Electric tool An electric tool is provided. The electric tool prevents anomalies in motor rotation due to dust and moisture sucked in together with a cooling wind, and is configured such that rotational position detection operations and switch operations are not affected. In the electric tool which drives a brushless DC motor using a controller, a magnetic body for rotational position detection is provided on a rotation shaft which can rotate integrally with a rotor, Hall ICs are provided to detect the rotational position of the magnetic body and output a position signal to the controller, and the magnetic body and the Hall ICs mounted on a substrate are arranged in a region isolated from the wind path of the cooling wind generated by rotation of a cooling fan. The Hall ICs are accommodated in a housing filled with resin.
US10173308B2	Tool for crimping, pressing or forming a workpiece A tool for crimping, pressing or deforming a workpiece includes a first grip element having a first grip portion; a second grip element having a second grip portion; a mechanism housing, which is arranged on the first grip element and has an end surface facing away from the first grip portion; a tool mechanism, which is enclosed by the mechanism housing and can be actuated to crimp, press or deform the workpiece by adjusting the first and second grip elements relative to one another; and an impact protection element, which is arranged on the first grip demerit and has two limbs and an end face portion, which interconnects the limbs. The mechanism housing is arranged between the limbs, and the end face portion extends beyond the end surface of the mechanism housing.
US10173307B2	Illuminated power tool A power tool with a chuck and a tool body having a housing, a motor received in the housing, a light array mounted to the housing, and an output spindle extending through the light array and which is rotationally driven by the motor. The chuck has a chuck body, a plurality of jaws, and an outer sleeve. A rear end of the chuck body is rotatably mounted on the output spindle. The chuck body has a plurality of jaw apertures and a plurality of light holes. The jaw apertures and the light holes extend through a front surface of the chuck body. Each of the jaws is received in a corresponding one of the jaw apertures. The outer sleeve is disposed about the jaws and the chuck body. Light emanating from the light array is transmitted through the light holes to illuminate a zone in front of the chuck body.
US10173306B2	Securing unit for securing adapter to wrench A wrench includes a handle and a driving head and a ratchet ring with a receiving hole is received in the driving head. An adapter is detachably inserted into the receiving hole and has a neck, an engaging portion and a reception hole. The neck on first end of the engaging portion has a first groove. A second groove is defined in the second end of the engaging portion. Multiple holes are defined through the bottom of the second groove and communicate with the reception hole. 33 A clip is engaged with the second groove and partially protrudes beyond the holes and exposed in the reception. A securing unit is connected to the driving head to secure or release the adapter. The receiving hole is connected with larger bits or sockets, and the adapter is connected with smaller bits or sockets.
US10173303B2	Clamping device A clamping device has a pair of first and second clamping arms rotatably supported with respect to a body, and a cam member having a cam surface is removably provided at one end of each of the first and second clamping arms. A pair of rollers pivotally supported by a block body constituting a drive unit are each in contact with the cam member. By a descent of the block body under the driving action of the drive unit, the cam surface of the cam member is pressed by the rollers, and the cam surface inclined in the displacement direction of the block body and recessed in a cross-sectional arc shape is pressed.
US10173300B1	Polycrystalline diamond compact, drill bit incorporating same, and methods of manufacture Methods of making superabrasive elements may include forming a first superabrasive body, forming discrete components from the first superabrasive body, and then forming a second abrasive element from the discrete components. For example, microstructures (e.g., micro-cylinders or other geometries) may be formed from the first superabrasive element, catalyst materials may be removed from the microstructures, with the microstructures being recombined and bonded during a subsequent high-pressure, high-temperature (HPHT) process. In other embodiments, superabrasive elements may be formed to include microfeatures formed in a surface of a superabrasive body or table. For example, blind holes or slots may be formed in a surface of the element for use in attaching the superabrasive table to a substrate. The holes may be coated to provide an impermeable surface, or they may be filled with a metallic material to enhance the attachment to a substrate.
US10173299B2	Polycrystalline diamond constructions having optimized material composition Diamond bonded constructions include a diamond body comprising intercrystalline bonded diamond and interstitial regions. The body has a working surface and an interface surface, and may be joined to a metallic substrate. The body has a gradient diamond volume content greater about 1.5 percent, wherein the diamond content at the interface surface is less than 94 percent, and increases moving toward the working surface. The body may include a region that is substantially free of a catalyst material otherwise disposed within the body and present in a gradient amount. An additional material may be included within the body and be present in a changing amount. The body may be formed by high-pressure HPHT processing, e.g., from 6,200 MPa to 10,000 MPa, to produce a sintered body having a characteristic diamond volume fraction v. average grain size relationship distinguishable from that of diamond bonded constructions form by conventional-pressure HPHT processing.
US10173298B2	Reversible lever for a guard assembly for a power tool A stop lever is provided for a power tool having a gear case and a guard member. The reversible stop lever is coupled to the gear case via a fastener. The stop lever includes a first arm and a second arm, and the fastener is removable to position the stop lever such that the first arm or the second arm of the stop lever engages the guard collar. The first arm includes a first surface and a second surface that are angled such that the guard collar can be rotated in a one direction without actuation of the second arm, but not in the opposite direction. The second arm of the stop lever includes surfaces that are angled to prevent rotation of the guard collar in either direction unless the second arm is actuated about the fastener.
US10173297B2	Chemical mechanical polishing conditioner and method for manufacturing same A chemical mechanical polishing (abbreviated as CMP) conditioner comprises a bottom substrate, an intermediate substrate and a diamond film The intermediate substrate is provided on the bottom substrate. The intermediate substrate comprises a hollow portion, an annular portion surrounding the hollow portion, and at least one projecting ring projecting out of the annular portion away from the bottom substrate. The projecting ring comprises a plurality of bumps arranged to be spaced apart from each other along an annulus region. The bumps are extended in a radial direction of the intermediate substrate. The diamond film is provided on the intermediate substrate. The diamond film is allowed for conforming to the bumps, so as to form a plurality of the abrasive projections.
US10173292B2	Method for assembling a magnetic attachment mechanism A magnetic attachment system for attaching a first object to a second object. A first magnet structure is attached to the first object and a second magnet structure is attached to the second object. The first and second objects are attached by virtue of the magnetic attraction between the first magnet structure and second magnet structure. The magnet structures comprise magnetic elements arranged in accordance with patterns based on various codes. In one embodiment, the code has certain autocorrelation properties. In further embodiments the specific type of code is specified. In a further embodiment, an attachment and a release configuration may be achieved by a simple movement of the magnet structures. In a further embodiment, the magnetic field structure may comprise multiple structures based on multiple codes.
US10173291B2	Low and extra low sulfur alloys for repair A method for repairing, refurbishing, or replacing a turbine engine component or sub-component includes the steps of providing a turbine engine component or sub-component having a site to be repaired, refurbished, or replaced providing a repair or replacement material having a sulfur content, which sulfur content is less than 10 ppm, and applying the repair or replacement material to the site on the turbine engine component to effect the repair, the refurbishment, or the replacement.
US10173286B2	Optical fiber coating to reduce friction and static charge Certain aspects of the present disclosure provide techniques and corresponding apparatus for making armored cables with one or more optical fibers contained therein. The techniques may be utilized to control an amount of excess fiber length (EFL) in the armored cables. The techniques may also allow introduction of one or more optical fibers directly into a welding process without using an inner tube in the final armored cable. The techniques may also be utilized to reduce friction and static charge on the optical fiber(s) as the fiber(s) are pushed through one or more guide tubes that protect the fiber(s) during the welding process.
US10173281B2	Bonded structure of dissimilar metallic materials and method of joining dissimilar metallic materials Disclosed herein are bonded structures and methods of forming the same. One embodiment of a bonded structure comprises first and second metallic layers and a bonding interface between the first and second metallic layers formed by diffusion and comprising a layer of at least one intermetallic compound. The intermetallic compound layer is formed in an area 52% or greater of an area of the bonding interface and has a thickness of 0.5 to 3.2 μm.
US10173270B2	Countersinking device and associated method A countersinking device includes an internal bore positioner adapted for receipt by a bore defined by a workpiece. A driver rod engaged with the internal bore positioner extends outwardly of the bore through a bore opening. A centering chuck, engaged about and axially movable along the driver rod, is configured to engage the bore opening to cooperate with the internal bore positioner to align the driver rod along a longitudinal axis of the bore. A counterbore is engaged about the driver rod, opposite the centering chuck from the internal bore positioner. The counterbore is rotatable about and is configured to be axially advanced along the driver rod to engage the bore opening and countersink the bore. A countersink depth control arrangement is associated with the counterbore and cooperates therewith to countersink the bore to a predetermined depth. An associated method is also provided.
US10173267B2	Tool clamping device A tool clamping device having a tool holder holding a tool, said tool holder being designed for insertion into a socket of a tool carrier, in particular a lathe, has a tool quick-change system.
US10173262B2	Systems and methods for monitoring temperature using acoustic waves during processing of a material Under one aspect, a method of processing a material includes heating a region of the material with a first energy source; exciting an acoustic wave in the material; and transmitting the acoustic wave through the heated region, the heated region changing at least one property of the acoustic wave. The method also can include detecting the change in at least one property of the acoustic wave; characterizing a temperature of the material in the heated region based on the detected change in at least one property of the acoustic wave; and comparing the characterized temperature of the material in the heated region to a threshold. The method further can include, based on the characterized temperature of the material in the heated region being less than the threshold or being above the threshold for an insufficient amount of time, modifying a property of the heated region with a second energy source.
US10173256B2	Radial rolling process for ring product that can control strain distribution of ring product The invention provides a radial ring rolling process for controlling strain distribution of a ring product. In the process, a ring blank is rolled by a main roll and a mandrel that are driven to rotate, while a gap between the main roll and the mandrel continuously decreases in the radial direction of the ring blank. The process includes (A) according to dimensions of the ring product and expected strain, a rolling ratio is firstly determined, dimensions of the ring blank is calculated based on the rolling ratio and the dimensions of the ring product; (B) a rotation speed curve of the mandrel is determined based on the rotation and the radial feeding speeds of the main roll; (C) the ring blank is rolled according to the rotation and radial feeding speeds of the main roll and the calculated rotation speed of mandrel in step (B).
US10173255B2	Systems and methods for arc and node design and manufacture A metal extrusion and nodes based structure is provided. The structure comprises one or more arc members connected by one or more node members, wherein the arc comprises (i) a wing feature which is configured to mate with one or more non-structural components, (ii) an internal passage feature which is configured to be inserted into a connecting feature of the corresponding node member, and (iii) one or more keying features formed from a mating interface with the corresponding node member.
US10173253B2	Methods for the development of commercial scale nano-engineered ultraconductive copper wire When forming ultra-conductive wire, multi-walled carbon nanotubes (MWCNTs) are dispersed and de-agglomerated in hot metal. The MWCNTs are dispersed in a precursor matrix via mixing and sintering to form precursor material, which is hot-extruded multiple rounds at a predetermined temperature to form a nano-composite material. The nano-composite material is inserted into a metal bar to form a nano-composite billet (306), which is subjected to multiple rounds of hot extrusion to form an ultra-conductive material. The ultra-conductive material is subjected to one or more rounds of hot wire drawing to form an ultra-conductive wire comprising a nano-composite filament.
US10173247B2	Rotating cleaning brush A rotating cleaning brush includes a connection pin to be clamped in a chuck of a machine for rotatingly driving the cleaning brush about its longitudinal axis. The cleaning brush includes a bristle carrier including a plurality of openings. The bristle carrier includes a first bristle bundle and a second bristle bundle being adjacent along the longitudinal axis. The first bristle bundle is located closer to the first end region of the cleaning brush than the second bristle bundle. Each of the bristle bundles includes a plurality of bristles and is located in one of the openings. The bristles of the first bristle bundle are designed to bend towards the longitudinal axis and then run parallel to the longitudinal axis so as to overlap the opening in which the second bristle bundle is arranged.
US10173238B2	Applicator An applicator for application onto and embossing microprofiling of a fluidic medium on a substrate, in particular in the aerospace sector, and a corresponding application device having such an applicator. The applicator has a circumferentially moving die that has an embossing profile, a press for the die and a stabilizing device, in particular a hardening device, for the applied medium. In addition, the applicator has a hollow support body, surrounded by the die at a distance forming a gap, the press being arranged in the gap. The application device has, in addition to the applicator, a handling device for a relative movement between the applicator and a workpiece.
US10173236B2	Nozzle control system and method A system for controlling nozzle flow rate includes a master node having an expected overall flow rate module configured to generate an expected overall flow rate of an agricultural product based on one or more sprayer characteristics, and an adjustment module configured to generate an error correction based on a difference between the expected overall flow rate and an actual overall flow rate of the agricultural product. A plurality of smart nozzles are in communication with the master node, each of the smart nozzles includes an electronic control unit in communication with one or more control valves and one or more nozzle assemblies. Each of the smart nozzles includes a target smart nozzle flow rate module configured to generate a target smart nozzle flow rate of the agricultural product based on the one or more sprayer characteristics. The target smart nozzle flow rate is adjusted according to the error correction.
US10173231B2	Systems, methods, and apparatuses for providing viscous fluid in a particular format and implementations thereof The present invention involves providing a viscous fluid in a particular format and implementations thereof. In particular, a viscous slave fluid is provided in a particular format, wherein the particular format can be an end result or an intermediate result for the viscous fluid. In the case of an intermediate result, the viscous fluid in the second format may be further processed to a third format. Implementations or applications include supercharged fuel injection systems, methods, and apparatuses for internal combustion, lean-burn oil pre-mixing systems, methods, and apparatuses for liquid fuel combustion, and medical or biomedical devices, systems, and methods.
US10173229B2	Electrostatic atomizing device An electrostatic atomizing device includes: a spray electrode and a reference electrode across which and the spray electrode a voltage is applied, the reference electrode being provided near the spray electrode, the spray electrode and the reference electrode being provided in an opening and an opening, respectively, which are provided on a device surface of the electrostatic atomizing device, and the opening being provided so as to reduce a ratio in which an atomized substance adheres to the device surface.
US10173228B1	Flow-adjustable shower unit A flow-adjustable shower unit comprises a water path connector, a water outlet assembly, and a connecting base arranged between the water path connector and the water outlet assembly to make the water path connector communicate with the water outlet assembly; the connecting base is a cylindrical cavity, a fixed baffle transversely dividing the cavity of the connecting base is arranged in the connecting base, and a first through groove is formed in the fixed baffle in a penetrating mode; a movable baffle is further movably mounted on the connecting base and abuts against the fixed baffle, and a second through groove is formed in the position, corresponding to the first through groove, of the movable baffle; the overlapping area between the first through groove and the second through groove can be adjusted by adjusting the position of the movable baffle, and thus the flow of the connecting base is adjusted.
US10173217B2	Sample processing method, sample processing chip, and sample processing apparatus Disclosed is a sample processing method for processing a target component in a sample by use of a sample processing chip having a storage portion and a droplet forming flow path, the sample processing method including: storing, in the storage portion, a mixture of the target component and a predetermined amount of a diluent for causing the target component to be encapsulated by one molecule or by one particle into a droplet; heating the mixture in the storage portion to cause thermal convection in the storage portion thereby to mix the target component and the diluent together; and in the droplet forming flow path, forming droplets in a dispersion medium, each droplet containing the diluted target component and a reagent that reacts with the target component.
US10173211B2	Organic-free synthesis of small pore zeolite catalysts The present invention is directed to methods of enhancing the catalytic activities of 8-MR zeolites, the methods comprising treating a precursor 8-MR zeolite that has been prepared without the use of an organic structure directing agent and having an Si/Al ratio of less than 5, with high temperature steam for a period of time sufficient to extract at least a portion of the aluminum from the precursor zeolite framework to form a steam-treated zeolite having an Si/tetrahedral Al ratio of greater than 5, wherein the steam has a temperature in a range of from about 350° C. to about 850° C. The compositions produced by these methods and their use in catalytic reactions are also provided.
US10173206B2	Modified Y-zeolite/ZSM-5 catalyst for increased propylene production Provided is a Fluid Catalytic Cracking catalyst composition having increased propylene production with respect to other Fluid Catalytic Cracking catalysts (measured at constant conversion). The catalyst composition comprises a particulate which comprises (a) non-rare earth metal exchanged Y-zeolite in an amount in the range of about 5 to about 50 wt %, based upon the weight of the particulate; and (b) ZSM-5 zeolite in an amount in the range of about 2 to about 50 wt %, based upon the weight of the particulate.
US10173201B2	Solutions and catalysts comprising group VI metal, group VIII metal, phosphorus and an additive This invention provides a catalyst formed by bringing together, in an aqueous medium, at least one phosphorus compound, at least one Group VI metal compound, at least one Group VIII metal compound, and an additive which is a) tetraethylene glycol, b) polyethylene glycol having an average molecular weight in the range of about 200 to about 400, c) a mixture of tetraethylene glycol and polyethylene glycol having an average molecular weight in the range of about 200 to about 400, or d) a mixture of (1) tetraethylene glycol and/or polyethylene glycol having an average molecular weight in the range of about 200 to about 400 and (2) one or more of monoethylene glycol, diethylene glycol, and triethylene glycol, forming an impregnated carrier; and drying the impregnated carrier. The molar ratio of additive to the total moles of Group VI metal and Group VIII metal is about 0.36:1 to about 0.6:1.
US10173200B2	Cerium-zirconium composite oxide, preparation method therefor, and application of catalyst Provided are a cerium-zirconium composite oxide, a preparation method therefor and application of a catalyst. The cerium-zirconium composite oxide has a composite phase structure, and comprises a cerium oxide phase and a cerium-zirconium solid solution phase, or consists of two or more cerium-zirconium solid solution phases with different crystal structures and different chemical compositions, wherein the chemical formula of the cerium-zirconium solid solution phase is CexZr1-x-yMyO2, where M is at least one selected from the group consisting of a rare earth element other than cerium, a transition metal element and an alkaline earth metal element, x is 15-85 mol %, and y is 0-20 mol %.
US10173199B2	Photocatalyst composite particles and method for producing same Disclosed are metal nitride photocatalyst particles and/or metal oxynitride photocatalyst particles having high dispersibility. The metal nitride photocatalyst particles and/or metal oxynitride photocatalyst particles having high dispersibility can be obtained by containing metal nitride photocatalyst particles and/or metal oxynitride photocatalyst particles, which are capable of splitting water under visible light irradiation, and a phosphoric acid polymer that is adsorbed on the surface of the particles. Further, because these particles have high photocatalytic activity under visible light irradiation, splitting water by using these particles can generate hydrogen and/or oxygen with high efficiency.
US10173195B2	Ethane and ethanol to liquid transportation fuels Processes relating to thermal activation (or cracking) of ethane to an intermediate, low purity raw ethylene stream in a first stage. This stream is then mixed with a stream of biomass-derived ethanol that may contain four volume percent or more of water. The resulting mixture is reacted over a suitable catalyst at temperatures and pressures suitable to produce gasoline-range and diesel-range blend stock.
US10173194B2	Systems for ionic liquid catalyzed alkylation based on a modular reactor We provide systems for ionic liquid catalyzed hydrocarbon conversion that comprise a modular reactor comprising a plurality of mixer modules. The mixer modules may be arranged in series. One or more feed modules are disposed between the mixer modules. Such systems may be used for ionic liquid catalyzed alkylation reactions. Processes for ionic liquid catalyzed hydrocarbon conversion are also disclosed.
US10173187B2	Processing machine, such as a kneading or mixing machine The processing machine (1) is adapted to carry a processing tool driven by a motor and includes a safety shield (4) adapted to at least partly shield the processing tool in relation to a user. The safety shield (4) is arranged displaceably away from its shielding position and a magnetically activatable safety arrangement (14) includes a safety switch (15) being operable between a passive state in which the motor (2) is allowed to operate and an activated state in which the motor is prevented from operation. The safety switch (15) is arranged to switch from its passive state to its activated state when the safety shield (4) is displaced away from its shielding position. At least one magnet (16) is arranged to hold said displaceable safety shield (4) in its shielding position and at the same time hold the safety switch (15) in its passive state.
US10173179B2	Polymer-ion-permeable membrane, composite-ion-permeable membrane, battery electrolyte membrane, and electrode composite An ion-permeable membrane is substantially free of holes and has excellent ion permeability, heat resistance, strength, and flexibility. A battery electrolyte membrane uses the ion-permeable membrane, and can form an electrode composite body. The polymer-ion-permeable membrane has an average radius of free volume of 0.32-0.50 nm.
US10173177B2	Process for the preparation of ethylene/chlorotrifluoroethylene polymer membranes The invention relates to a process for the production of membranes based on ethylene/chlorotrifluoroethylene polymers having a melting temperature not exceeding 200° C. The process relies on the diffusion induced phase separation of the ethylene/chlorotrifluoroethylene polymer from a solution and comprises the steps of providing a solution comprising an ethylene/chlorotrifluoroethylene polymer having a melting temperature not exceeding 200° C. in a solvent; casting the polymer solution into a film; immersing the film in a non-solvent bath to precipitate the polymer. Membranes made of compositions comprising an ethylene/chlorotrifluoroethylene polymer having a melting temperature not exceeding 200° C. and at least one second polymer are also disclosed.
US10173174B2	Membrane stacks A process for preparing a membrane stack comprising the steps of: (i) interposing a curable adhesive between alternate anion exchange membranes and cation exchange; and (ii) curing the adhesive; CHARACTERIZED IN THAT said adhesive, when cured, has a Shore A hardness of less than 70 and an elongation at break of at least 50%.
US10173168B2	Vapor separator and dehumidifier using the same A vapor separator in an embodiment is arranged between a first space and a second space, and is used to allow vapor existing in the first space to permeate in the second space by making a vapor pressure in the second space lower than a vapor pressure in the first space. The vapor separator in the embodiment includes: a porous body including a first face in contact with the first space and having a convexo-concave structure, a second face in contact with the second space, and fine pores passing to the second face from at least wall of the first face which constitutes the convexo-concave structure; and water existing in the fine pores of the porous body.
US10173167B2	Composite method of trapping carbon dioxide in gas mixture A hybrid method for capturing CO2 from a gas mixture is provided, comprising a step of contacting the CO2 containing gas mixture with a slurry consisting of a liquid medium, imidazole or imidazole derivative(s), and a metal-organic framework material (MOFs). For the slurry system, the mass fraction of the imidazole or imidazole derivative(s) in it ranging from 2 to 50% and the mass fraction of the metal-organic framework material in it ranging from 5 to 25%. In the technical solution provided in the present invention, through combining absorptive separation by the liquid solution in which the imidazole or imidazole derivative(s) is dissolved, adsorption separation by the MOF material suspended in the solution, and selective permeation separation by a liquid medium film forms on the outside surface of the suspended MOFs, an absorption-adsorption hybrid separation effect for CO2 gas mixtures is efficiently achieved. In the CO2 capture method provided in the present invention, conventional absorption separation and adsorptive separation technologies are effectively combined, furthermore, the addition of imidazole or imidazole derivative(s) substantially increases both the CO2 capture ability and capture amount of the MOFs/liquid slurry, showing a great potential in industrial applications.
US10173160B2	Effluent removal system and method of use An effluent removal system comprising, a vacuum plenum to receive, at an inlet of the vacuum plenum, an effluent mixture comprising a gas and a liquid, a droplet separator having an inlet coupled to an outlet of the vacuum plenum, the droplet separator to substantially remove the liquid from the effluent mixture and a blower having an inlet coupled to a gas outlet of the droplet separator, the inlet of the blower to receive the gas of the effluent mixture after the liquid has been substantially removed from the effluent mixture by the droplet separator.
US10173156B2	Filter cartridge A filter cartridge includes a casing. A filter medium is disposed within the casing. A female inlet port and a female outlet port are mounted to the casing at an end portion of the casing. The female inlet port is offset from the female outlet port along the radial direction at the end portion of the casing.
US10173153B2	Liquid filter assembly and methods A liquid filter assembly includes a porous tubular support member and a filter element removably and replaceably oriented in the interior volume of the support member. A bypass valve arrangement is provided to permit at least some unfiltered liquid to bypass media in the filter element. A dynamic seal can help to seal the bypass valve arrangement.
US10173150B2	Wall adaptor for filter underdrain A filtration system having an underdrain block and an underdrain wall adaptor. The underdrain wall adaptor includes a vertical end and horizontal base. The vertical end extends from a top wall to a bottom wall of an underdrain block and mates with an end portion of an underdrain block to secure the underdrain wall adaptor to the underdrain block. The horizontal base extends from the vertical end. The invention also includes a method of installing an underdrain wall adaptor. The underdrain wall adaptor controls air and water passage between the flume and the underdrain.
US10173145B2	Carbon dioxide separation system A treatment tower of a carbon dioxide separation system includes a treatment container of a tower shape, having inner space which is virtually dividable into a regeneration treatment chamber, drying treatment chamber, and adsorption treatment chamber arranged in this order from the top to the bottom, by two hindrances which are upper and lower hindrances and hinder the downward movement of the adsorbent while maintaining the bedded (layered) flow of the adsorbent, a first passage member formed with ejection holes which eject a gas used in a treatment in each of the treatment chambers to a lower portion of each of the treatment chambers, and a second passage member formed with a gas discharge hole which discharges the gas having contacted the adsorbent from an upper portion of each of the treatment chambers. In the two treatment chambers on the lower side, gas discharge holes are formed below the hindrances.
US10173144B2	Lift system with moving cam assembly and related methods A lift system for lifting a load includes a counterweight, a base unit, a fly line, a load line, and pulleys. The base unit includes a movable cam assembly coupled to a fixed frame. The cam assembly includes a cam member that is rotatable relative to a carriage of the cam assembly. The cam assembly can be moved between first and second positions relative to the frame member, and prevents movement of the fly line through the base unit in the first position, while movement of the fly line through the base unit is allowed when the cam assembly is in the second position.
US10173143B2	Magnetic construction system and method A magnetic construction system comprised of plural multi-shaped structural bodies each containing one or more captured magnets, wherein each magnet is free to rotate within its respective retaining pocket to align in magnetic polarity with rotatable magnets in adjacent structural bodies. Surface geometry around each magnet may include a radial detent feature which provides lateral and rotational stability between magnetically coupled structural bodies, or a radial recess which allows free rotation of respective structural bodies about the polar axis of magnetic coupling.
US10173138B2	Storage medium, information processing apparatus and control method for deciding object types and appearances based on hardware resource usage amounts A computer is caused to execute processing that that determines, based on a first usage amount of a hardware resource which is allocated for processing corresponding to objects of a first category including an essential object located in a target scene, a second usage amount of the hardware resource that is able to be allocated for processing for objects of a second category different to the first category. Also, the computer is caused to execute processing of deciding, for objects of the second category which are located in the target scene, types of those objects and an outer appearance parameter for each type based on the second usage amount and information for deciding outer appearances for when the objects of the second category are located in the target scene.
US10173131B2	Display device and game machine A display device has a display panel including an image display area in which an image is displayable, a light guide plate arranged at a back of the display panel, the light guide plate comprising a transparent material and having a first incident surface and a second incident surface, a first light source facing the first incident surface, a second light source facing the second incident surface, and a controller configured to control turning on and turning off of the first light source and the second light source and to control an image displayed on the display panel. The light guide plate includes an emission surface facing the display panel, and a plurality of first prisms arranged in an area in correspondence with the image display area on a surface opposite to the emission surface.
US10173130B2	Information processing system, extended input device, and information processing method In a state where an extended input device is secured to a data transmission device, an image capturing unit of the data transmission device captures an image of a light emitting unit that emits light, an image of which is allowed to be captured by the image capturing unit in accordance with a user input and/or a user operation, and data generated based on at least the captured image is transmitted to an information processing apparatus. The information processing apparatus executes an information process based on the transmitted data.
US10173128B2	Games, and methods for improved game play in games of chance and games of skill A variety of games and methods for enhancing game play are provided. In one aspect, a secondary or ancillary game is played in parallel with a first game, such as a lottery ball draw. Yet another embodiment of game play provides for the repurposing of an existing taped game show. The previously recorded game show would be segmented into subsets of issues, for example, presentation of questions or answers (as in the case of Jeopardy), those issues would be presented to one or more players, a response would be received from those players, and the answer would be compared to the correct answer. Scoring would then rank players relative to one another or to indicate the amount of the prize.
US10173127B2	Studded jigsaw puzzle The jigsaw puzzle includes a baseplate used with attachable puzzle pieces. The baseplate has multiple upward-facing engagement mechanisms that are engaged with corresponding and complementary puzzle piece rear-facing engagement mechanisms. The rear-facing engagement mechanisms and the complementary puzzle piece rear-facing engagement mechanisms are designed so as to leave a space between the bottom of the puzzle piece and the top surface of the baseplate to facilitate removal of the puzzle pieces. An optional pry tool can be inserted in to the space to easily remove the puzzle pieces after play, storage, or display. An optional hanger/joiner can be utilized to hang the completed puzzle vertically and/or to join two baseplates to create increased play opportunities.
US10173125B2	Circular logic game A circular logic puzzle The “CIRCULAR” puzzle has similarities to Sudoku and Latin squares in problem solving, and in this new circular format the many different varieties of game play and playing surfaces can be produced gives many new challenges and perspectives for those who enjoy solving logic puzzles.
US10173123B2	Modular pitching mound with replaceable trays A modular pitching mound includes a removable drive area, a removable landing area, a modular level and sloped section, and a modular mound skirt section. The removable drive area includes an area for a pitching rubber. The modular level and sloped section that, when assembled, supports the removable drive area in a first position and at least encircles the removable landing area. The removable drive area and/or the modular level and sloped section includes a removable mechanism for assisting with removal of the removable drive area from the modular level and sloped section. The modular mound skirt section couples to and encircles the modular level and sloped section.
US10173122B2	Storable exerciser device An exerciser device comprising a telescopically deployed vertically oriented tower, a telescopically deployed horizontally oriented corridor and a housing provided at a bottom end of the telescopically deployed vertically oriented tower, wherein the housing is adapted to provide a neatly configured storage medium of the exerciser device, while further providing a support base for the deployment of the vertically oriented tower and a means for a controlled deployment of the horizontally oriented corridor.
US10173115B2	Adjustable training golf tee An adjustable training golf tee is provided. The adjustable training golf tee may include a top body, a stem and a base. The top body may have a first side and a second side, wherein the second side forms a concentric threaded recess, wherein the first side forms a concentric stem aperture communicating the first side to the threaded recess. The stem may have a first end and a second end, wherein the first end is dimensioned and adapted to rest a golf ball thereon. The base may include a threaded flange and a spike perpendicularly joined thereto, wherein the threaded recess is dimensioned and adapted to rotatably mate with the threaded flange, and wherein the stem aperture is dimensioned and adapted to be slidably receive the stem secured to the base.
US10173113B2	Sub-assembly for a golf bag and a golf bag system for recipient self-assembly A golf bag includes a collapsible sub-assembly including a divider top and a base, a plurality of first snap-fit connectors provided around a portion of an outer perimeter of the divider top, and a flat having a divider top end opposite a base end, an interior side, and an exterior side. The flat includes a plurality of second snap-fit connectors provided along a portion of the divider top end. The flat attaches to the sub-assembly by mating snap-fit engagement of the plurality of first snap-fit connectors around the divider top with the plurality of second snap-fit connectors along the divider top end.
US10173109B1	Iron-type golf club head with damping features An iron-type golf club head comprising a body with a striking face and a hollow cavity portion, a medallion, and a damping insert that is spaced from, and does not contact any portion of, the striking face is disclosed herein. The damping insert is trapped between the medallion and a support structure that extends from the body of the club head approximately parallel with the striking face, and is at least partially suspended over or in the cavity portion. The structure may be an elongated stiffening member that connects upper and lower portions of the body to one another, or a rectangular lip section. The damping insert is affixed to only one of the medallion and the structure with an adhesive material, and damps vibration in the striking face after the striking face makes contact with a golf ball, while the striking face is rebounding from impact.
US10173106B2	Golf club having a reinforced ball striking plate A ball striking device includes a ball striking plate having a front surface configured to strike a ball and a rear surface opposite the front surface. The ball striking plate has a desired-contact region and a perimeter. One or more spoke-like reinforcement ribs may be located on the rear surface and may radiate away from the desired-contact region toward the perimeter. At least one of the spoke-like reinforcement ribs may be located in an upper-toe quadrant or in an upper-heel quadrant of the rear surface. One or more encircling reinforcement ribs may be located on the rear surface. The one or more encircling reinforcement ribs may be at least partially encircling the desired-contact region. A thickened portion of the ball striking plate may be positioned behind the desired-contact region of the ball striking plate. The ball striking device may be a golf club head.
US10173101B2	Athletic performance monitoring systems and methods in a team sports environment Systems and methods for sensing and monitoring various athletic performance metrics, e.g., during the course of a game, a practice, a training session, training drills, and the like, are described. These systems and methods can provide useful metrics for players and coaches relating to athletic performances in various sports, including various team sports.
US10173100B2	Sport training equipment A system for recording and analyzing an activity, such as a golf activity, is provided. The system comprises an impact detection device and one or more video capture unit for recording and displaying recorded activities. Preferred activities are saved, and may be viewed at a separate viewing unit located remote from the video capture unit. The remote viewing unit allows for replay and analysis of the saved activities. In addition, saved activities and data may be uploaded to the Internet for later viewing and analysis.
US10173094B2	Adjustable rehabilitation and exercise device An adjustable rehabilitation and exercise device, including a rotary member rotatably mounted on a hub; a mount having a ring located adjacent to the rotary member with a lock selectively engageable with the rotary member to lock the ring at an angular position relative to the rotary member, and an arm connected to the ring and extending radially relative to the rotary member and having a movable carriage associated therewith to move radially relative to the rotary member and lockable to position the carriage at a radial position relative to the rotary member; and a patient engagement member connected to the mount and movable with the carriage.
US10173090B2	Tensioning element for tensioning a jumping mat on a frame of a trampoline The invention relates to a tensioning element (1) for tensioning a jumping mat (15) on a frame (16) of a trampoline (19) with the aid of an elastic cable (18), wherein the tensioning element (1) comprises a basic body (2) with a plurality of retaining elements (3a-3c) for retaining the elastic cable (18). In order to allow variable adjustment of the mat tensioning, the invention proposes to provide a plurality of retaining elements (3a-3c) on the same side of the basic body (2), and therefore the elastic cable can be positioned optionally around one or more of the retaining elements (3a-3c).
US10173088B2	Bracket for installation of a fire protection sprinkler A support bracket includes a support beam and a center bracket. The center bracket has a body that defines an opening to receive a sprinkler fitting, and a closure assembly, including a closure member having a first end rotatably connected to the body, and a second end having a handle. The closure assembly is movable between an open position and a closed position. When in the closed position, the closure assembly presses the sprinkler fitting against one of the body and the support beam, thereby urging the center bracket against the support beam to maintain the center bracket stationary relative to the support beam. In addition, the closure assembly includes a lock that engages with the closure assembly when the closure member moves from the open position to the closed position, and that prevents the closure member from returning from the closed position to the open position.
US10173087B2	Fire suppression apparatuses and methods for suppressing a fire with an object A fire suppression apparatus is described that includes a base and a lid. The base has an opening and walls defining an internal area. The base also includes a sleeve with a portion positioned in the internal area and around a perimeter of the walls, and the sleeve defines a region of the internal area for placing an object. The sleeve also has an opening for placing the object into the region. The base further has a first fire suppressing powder positioned in the internal area between the sleeve and the walls. The lid covers the opening of the base, and has a cavity, a second fire suppressing powder contained inside the cavity, and a divider positioned to cover the cavity of the lid. Methods for suppressing a fire of an object are also described.
US10173083B2	Lung demand valve There is disclosed a lung demand valve comprising: a body within which is disposed a diaphragm and a valve assembly having a valve inlet, the valve assembly and diaphragm arranged to cooperate to control the delivery of breathable gas to a user. There is also provided a breathable gas inlet fluidically connected to the valve inlet inside the body and arranged to be fluidically connected to a supply of breathable gas; and a whistle coupled to the body. The whistle has a whistle inlet fluidically connected to the breathable gas inlet inside the body and a whistle outlet disposed outside the body. In use, when the pressure of the breathable gas in the breathable gas inlet is less than a threshold, breathable gas flows from the breathable gas inlet through the whistle inlet and outlet thereby causing the whistle to sound outside of the body.
US10173082B2	Combined exhale and inlet valve for respirator A valve assembly including a mask end and a supply end is provided. The valve assembly includes a housing assembly, an inhale valve, and an exhale valve. The housing assembly defines a first air passageway configured for inhalation and a second air passageway configured for exhalation. At least a portion of the second air passageway is disposed peripherally around the first air passageway. The inhale valve is configured to be biased to an open position when subject to a reduction in pressure due to inhalation, and to be biased to a closed position when subject to an increase in pressure proximate due to exhalation. The exhale valve is configured to be biased to a closed position when subject to a reduction in pressure due to inhalation, and to be biased to an open position when subject to an increase in pressure due to exhalation.
US10173081B2	Descender A descender (10) comprises a rear or base plate (20), a front plate (22) which is fixedly mounted to the base plate, generally parallel to and spaced from the base plate and an arm (30) which is pivotally mounted to the base plate and/or the front plate for movement between the two plates. The arm (30) defines a generally curved channel (38) through which a rope (14) may pass. The channel is defined between a sheave (34) and a wall (37) of the arm and defines an entrance (38a) and an exit (38b) for the rope. The sheave (34) is pivotable about an axis, the sheave being lightly biased towards a first or rest position. Pivoting of the sheave about the axis in a first direction, away from the rest position, causes an increase in the friction applied to the rope passing through the channel, typically by causing the exit of the channel to narrow. A handle (46) is provided, operation of which may cause the sheave (34) to rotate towards its rest or neutral position thereby allowing faster passage of the rope through the descender. The descender (10) includes means for connecting the descender to a harness or the like.
US10173078B2	Two-dimensional x-ray imaging of a target volume Methods of two-dimensional x-ray imaging of a target volume and tracking a target structure contained within a target volume are described.
US10173070B2	Pass-through assembly A pass-through assembly including a first wall 110d having oppositely-directed inner and outer sides, 112, 114, the first wall 110d defining a first opening 116 extending from the inner side 112 to the outer side 114; an elongated structure 118 extending into the opening 116 from the outer side 114 of the first wall 110d; a first material 130 contacting the first wall 110d and the elongated structure 118 so as to at least partially seal the opening 116, and a second material 140 different from the first material 130, the second material 140 overlying the first material 130 on the outer side 114 of the wall 110d, the second material 140 adhering to the elongated structure 118 and the first wall 110d, the second material 140 having at least one physical property different than a corresponding physical property of the first material 130.
US10173068B2	Mitigating false messaging in leadless dual-chamber pacing systems and other IMD systems Implantable medical devices (IMDs), and methods for use therewith, reduce how often an IMD accepts false messages. Such a method can include receiving a message and performing error detection and correction on the message. Such a method can also include determining a quality measure indicative of a quality of the message and/or a quality of a channel over which the message was received, and determining whether to reject the message based on the quality measure.
US10173064B2	Power supply disconnect current measurement for an implantable medical device An implantable medical device (IMD) is disclosed having measurement circuitry for measuring one or more currents in the IMD, such as the currents drawn from various power supply voltages. Such currents are measured without disrupting normal IMD operation, and can be telemetered from the IMD for review. Switching circuitry in line with the current being measured is temporarily opened for a time period to disconnect the power supply voltage from the circuitry being powered. A voltage across a capacitance in parallel with the circuitry is measured when the switching circuitry is opened and again closed at the end of the time period, with the circuitry drawing power from the charged capacitance during this time period. The average current drawn by the power supply voltage is determined using the difference in the measured voltages, the known capacitance, and the time period between the measurements.
US10173062B2	Implanted pulse generators with reduced power consumption via signal strength/duration characteristics, and associated systems and methods Implanted pulse generators with reduced power consumption via signal strength-duration characteristics, and associated systems and methods are disclosed. A representative method for treating a patient in accordance with the disclosed technology includes receiving an input corresponding to an available voltage for an implanted medical device and identifying a signal delivery parameter value of an electrical signal based on a correlation between values of the signal delivery parameter and signal deliver amplitudes. The signal deliver parameter can include at least one of pulse width or duty cycle. The method can further include delivering an electrical therapy signal to the patient at the identified signal delivery parameter value using a voltage within a margin of the available voltage.
US10173061B2	Methods and apparatus for stimulation of biological tissue In illustrative implementations of this invention, interferential stimulation is precisely directed to arbitrary regions in a brain. The target region is not limited to the area immediately beneath the electrodes, but may be any superficial, mid-depth or deep brain structure. Targeting is achieved by positioning the region of maximum envelope amplitude so that it is located at the targeted tissue. Leakage between current channels is greatly reduced by making at least one of the current channels anti-phasic: that is, the electrode pair of at least one of the current channels has a phase difference between the two electrodes that is substantially equal to 180 degrees. Pairs of stimulating electrodes are positioned side-by-side, rather than in a conventional crisscross pattern, and thus produce only one region of maximum envelope amplitude. Typically, current sources are used to drive the interferential currents.
US10173060B2	Methods for peripheral nerve stimulation A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.
US10173058B2	Functional electrical stimulation ergometer including automatic spasm control This invention controls stimulation levels and cycling cadence on an FES ergometer to minimize or prevent the occurrence of spasm in spinal cord injured or other neurologically impaired patients.
US10173057B2	Device and method of electroporating drug-delivering by using hollow needle electrode An electroporating drug delivering device using hollow needle electrode includes a drug delivering head, a control console as well as a control line and a tube for connecting the drug delivering head and the control console. The drug delivering head includes a universal joint, a camera, an illuminating lamp, a molecular drug delivery structure, an electric connector, a grille, a hollow needle electrode array, and a stretchable structure. The control console includes a display for observing images, a rocker for controlling the universal joint, and a remote starting unit for controlling the generation of electric pulses. The control console is connected with the electric connector inside of the drug delivering head by the line arranged inside of the tube. The electroporating drug-administration device enhances the drug utilization efficiency and reduces the treatment time, and can accurately adjust the intensity and region of the electric field.
US10173054B2	Implantable device An implantable medical device including at least one elongate electrical line with a first electrical component as a functional conductor, and at least one second electrical component with an electrical length. The first electrical component includes a proximal end and a distal end, wherein the distal side is in electrical contact with tissue or blood. The first electrical component is in electrical contact with the at least one second electrical component, and wherein the electrical length of the at least one second component corresponds to at least a tenth of a wavelength (λ/10) of electromagnetic waves in a radiofrequency range.
US10173052B2	Pacing guidewire Guidewires and methods for transmitting electrical stimuli to a heart and for guiding and supporting the delivery of elongate treatment devices within the heart are disclosed. A guidewire can comprise an elongate body, including first and second elongate conductors, and at least first and second electrodes. A distal end portion of the elongate body can include a preformed bias shape, such as a pigtail-shaped region, on which the first and second electrodes can be located. The preformed bias shape can optionally be non-coplanar relative to an intermediate portion of the elongate body. The first and second elongate conductors can be formed of a single structure or two or more electrically connected structures. The conductors can extend from proximal end portions to distal end portions that electrically connect to the first and second electrodes. A corewire can extend the length of the elongate body, can at least partially form the first conductor, and can be at least partially surrounded by the second conductor.
US10173047B2	Device for augmenting blood flow, tissue perfusion and fluid distribution by neuromuscular stimulation in horses and other non-human mammals The invention relates to a method and device for neuromuscular stimulation of one or more muscles, or muscle groups, with one or more beneficial effects selected from increasing arterial, venous and capillary blood flow, increasing flux of interstitial fluid and lymphatic drainage, increasing tissue oxygenation, enhancing heat distribution, enhancing the distribution of pharmaceutical products, and enhancing performance and recovery from exertion in horses.
US10173046B2	Connector system for releasably connecting fluid conduits Disclosed herein are embodiments of a connector system for releasably connecting together tubes, for example medical tubing, and methods of making and using such a connector system, whereby the connector system includes a female coupler having a first passageway, a male coupler having a second passageway, a catch movably coupled to the female coupler, and a catch-receiving element coupled to the male coupler. The connector system further includes a release element movably coupled to the female coupler, whereby travel of the release element along or over a female coupler outer surface of the female coupler disengages the catch from the catch-receiving element to achieve a disconnected condition of the connector system. Further disclosed herein are embodiments of a connector system for releasably connecting together tubes, whereby the connector system includes at least one valve biased by a valve-biasing member disposed external to or outside of the fluid flow path.
US10173041B2	Applicators A surgical preparation applicator device has a pre-loaded container of surgical preparation liquid, the container having a front closure at its front end. The container is received in an applicator body which includes a tubular receiving structure, movable from an initial position to an open position whereby a cutter of the applicator body opens the front closure to allow liquid to flow forwardly to an applicator pad. The applicator body defines a flow path between the container and the applicator pad. The container has separate chambers containing different component liquids of the surgical preparation liquid. The chambers are separated by an internal wall and being side-by-side, each having a front opening at the front end of the container with the front closure closing off both front openings.
US10173031B2	Interchangeable flush/selective catheter A combination flush catheter and selective catheter as one convertible catheter and methods of using the same. The selective catheter may be a reverse curve or guide catheter. The additional steps of removal of the flush catheter and re-insertion of the selective catheter may be eliminated, reducing the possibility of errors and making the procedure smoother and shorter.
US10173029B2	Deflection control catheters, support catheters and methods of use A deflection and support catheter provided for improved manipulation of elongated medical devices used during percutaneous procedures in difficult to reach situations. In particular, the deflection and support catheters can facilitate placement of guidewires, guide catheters, and intervention devices such as angioplasty balloons and stent delivery devices.
US10173028B2	Magnetic resonance imaging compatible catheter A method, consisting of passing a cylindrical carbon fiber through a press so as to produce a flat ribbon. The method further includes weaving multiple strands of the flat ribbon together to create a cylindrical braid.
US10173026B2	Infant calming aid An infant pacifying apparatus which includes: sound system includes a sound generator and associated power source; an auditory output device associated with the sound system; a receiving portion is configured to: be located on a hand or an arm of an adult cradling an infant; and house or be connected to a housing for containing: the auditory output device; or the sound system and auditory output device.
US10173025B2	Automated drug delivery systems A system for delivering drug is provided. The system includes an adapter and a device. The adapter is configured to establish fluid communication with a gas conduit of a ventilator circuit. The device includes an actuation member and an actuator. The actuation member is configured to pivot. A canister containing drug is disposed between the adapter and the actuation member. The actuator is engaged to the actuation member such that the actuator selectively causes pivotal movement of the actuation member, causing the actuation member to apply pressure over the canister, thereby causing the canister to deliver drug into the adapter.
US10173023B1	Oropharyngeal device An oropharyngeal device is disclosed for insertion into the oral cavity and the oropharynx of an individual. The oropharyngeal device comprises a tubular member extending between a proximal end and a distal end. The tubular member includes a channel extending between the primary aperture and the secondary aperture. A flange is coupled to the proximal end of the tubular member. The tubular member defines a gradual narrowing of the tubular member between the proximal end and the distal end for avoiding gagging reflex of the individual upon insertion of the distal end of the tubular member through the oral cavity and positioned adjacent to the epiglottis. The tubular member defines an arcuate shape for depressing the tongue and maintaining airway patency between the oral cavity and the epiglottis.
US10173018B1	Tamper resistant clamp A system and method for deterring potential illicit use of extended-installations of catheters associated with patient care. A pair of legs are moveably associated together to collectively define a needle-defeating pathway between a pair of scissoring, offset, pinching surfaces disposed on mating surfaces of the legs when the legs are closed and clamped to an indwelling catheter. A single-use tamper evident locking system both maintains the legs closed and provides tamper evidence when opened, such as by disabling the locking system from further locking operation.
US10173016B2	Dispensing speed control mechanism and injection device The invention refers to a dispensing speed control mechanism for use in an injection device having a release button, which is displaceable to initiate dispensing of a set dose, a first component part, which is driven by a power reservoir during dose dispensing, and a second component part, which is stationary during dose dispensing. The speed control mechanism includes friction means for retarding the first component part during dose dispensing depending on the position of the release button. Further, the invention refers to a handheld injection device with such a speed control mechanism.
US10173014B2	Cap assembly The present invention relates to a cap assembly 10 configured to be connectable to a suitable medicament delivery device having a distal and a proximal end. The cap assembly 10 according to the present invention comprises a removable outer 12 cap and a removable inner 16 cap movably connected in relation to each other. Further, said cap assembly is configured to allow said removable outer cap and said removable inner cap to be fixedly connectable to each other such that the removable outer cap is prevented of being movable with respect to the removable inner cap only when the medicament delivery device is held in a substantially vertical position such that both said removable outer cap and said removable inner cap can be removed from the cap assembly.
US10173013B2	Medical syringe, gasket to be used for syringe, and gasket production method Laminated gasket free from liquid drug leakage. A gasket (13) for a medical syringe, with main body (14) made of elastic material, and film (15) provided on a surface of main body (14). Gasket (13) has a circumferential surface portion (17) for contact with an inner peripheral surface of a syringe barrel (11) and an annular groove (22) formed circumferentially in a surface portion of the film in the circumferential surface portion thereof. Annular groove (22) has outer edge portions (24) provided along opposite edges (23) thereof as projecting from an unprocessed surface portion of the film. Annular groove (22) has a groove formation start point and a groove formation end point connected to each other in a groove connection region. Outer edge portions (24) provided along the opposite edges of the annular groove have a maximum-to-minimum height difference of ≤5 μm in the groove connection region.
US10173012B2	Medicament delivery device with two drive springs A medicament delivery device includes a case, a first plunger, a second plunger arranged telescopically with the first plunger, a first drive spring biasing the second plunger relative to the case, and a second drive spring biasing the first plunger relative to the second plunger.
US10173011B2	Medical device including an air evacuation system Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.
US10173009B2	Door and doorstop for portable one use drug delivery apparatus An aspect of some embodiments of the current application is a doorstop to a drug delivery apparatus that encourages a user of the apparatus to perform the proper usage steps in the proper order. For example, a user may be expected to receive an injector in a transport state, open it to an open state, insert a cartridge, and/or close the cartridge before operation. The doorstop may have an obstructing mode, optionally preventing closing of the door. The cartridge may optionally have a non-obstructing mode allowing closing of the door. Inserting the cartridge may optionally cause a doorstop to move from the obstructing mode to the non-obstructing mode. In the non-obstructing mode the doorstop may optionally prevent removal of the cartridge.
US10173002B2	Catheter devices with needle guards and related methods Needle devices are described. The needle devices can have a catheter hub, a needle hub, a housing located between the catheter hub and the needle hub. The housing can have an engagement mechanism to removably attach the housing to the catheter hub. The housing can further include a release element to release the engagement mechanism from the catheter hub to disengage the housing from the catheter hub. A flow regulator can be positioned inside the catheter hub. The flow regulator can include a stem and a sleeve.
US10173000B1	Systems, apparatuses and methods for tissue and substance removal, delivery and/or transplantation Systems for tissue removal, delivery and/or transplantation include a dispensing canister having a canister wall and a beveled or sloped canister bottom panel carried by the canister wall, a pump disposed in fluid communication with the dispensing canister and a vibrational injection apparatus disposed in fluid communication with the pump. Injection apparatuses are also disclosed.
US10172997B2	Implantable solid-liquid drug delivery apparatus, formulations, and methods of use Embodiments provide apparatus and methods for delivering liquid form medication within the body wherein the medication is stored in solid form and then mixed with a liquid in an apparatus implanted within the body. One embodiment provides an implantable apparatus for in vivo delivery of medication comprising a housing including a reservoir, a store of solid form medication (SSM) and a pump. An SSM element is added to the reservoir along with fluid to form a medication solution comprising at least one drug. The medication solution is then delivered to a delivery site using a pumping means to pump solution from the reservoir through a delivery member such as catheter to a delivery site. Embodiments of the invention are particularly useful for delivering medication to a patient to treat a medical condition over an extended period of time without requiring the patient to take external medication.
US10172991B2	Modular dialysate regeneration assembly A customizable modular dialysate regeneration assembly with connectable sorbent packaging systems. The dialysate regeneration assembly can be customized based on patient parameters or dialysis session parameters. A processor can be included that can determine the correct amount of each sorbent material necessary for a given patient and a given dialysis session.
US10172989B2	Portable hemodialysis machine and disposable cartridge with blood leak sensor A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate. The reused dialysis machine possesses a reservoir for dialysate, various sensors including a blood leak sensor assembly, and a processor connected to the various sensors for controlling and monitoring hemodialysis treatment. The blood leak sensor assembly includes a light source for emitting light through the dialysate flow path and a light sensor for receiving light having passed through the dialysate flow path. The processor is connected to the light source for determining whether blood has leaked from the blood flow path into the dialysate flow path. Preferably, the light source emits light having two peak wavelengths.
US10172986B2	Blood pump integrated in a housing front A device for extracorporeal blood treatment, in particular a dialysis machine, including a peristaltic pump for conveying fluid from a low-pressure side to a high-pressure side, the peristaltic pump comprising a rotor which is rotatable around a rotor axis and a support area which is formed around the rotor axis in an arcuate manner, with an elastically deformable fluid line being able to be positioned between the rotor and the support area and being deformed between the rotor and the support area with rotation of the rotor while forming a cross-sectional constriction, so that upon rotation of the rotor with respect to the support area a fluid in the fluid line is conveyed from the low-pressure side to the high-pressure side. The device includes a machine housing part realized as a formed sheet metal part, wherein the support area is formed in the machine housing part by plastic deformation.
US10172985B2	Catheter device having a coupling device for a drive device The invention relates to a catheter device, having a hollow catheter in the catheter cavity of which a moveable shaft is guided, having a proximal coupling device, for detachable coupling of a drive device, the coupling device having a coupling cavity which is open towards the drive device and into which the shaft or an extension of the shaft protrudes with a connection element for mechanical coupling of a motor shaft, the coupling cavity having a germ barrier for reducing the pathogenicity of pathogenic substances or microorganisms.
US10172984B2	Reduced-pressure treatment and debridement systems and methods A reduced-pressure treatment system for debriding a treatment area of a tissue site and applying reduced pressure is disclosed. The reduced-pressure treatment system includes a hydrogel having a blocked acid debriding agent. The hydrogel is adapted to cover the treatment area and enhance autolytic debridement at the treatment area. The reduced-pressure treatment system includes a manifold that is adapted to cover the hydrogel and distribute reduced pressure to the tissue site. The reduced-pressure treatment system also includes a sealing drape for forming a fluid seal over the tissue site and manifold. Other systems, methods, and dressings are presented.
US10172978B2	Medical device for short time use with quickly releasable antibacterial agent A method is presented for providing a medical device with antibacterial activity, whereby a substrate material coated with a hydrophilic polymer is provided, the hydrophilic polymer exhibiting a low friction when wetted; also provided is a colloidal solution comprising chemically reduced particles of an oligodynamic metal and a hydrophilic polymer, the hydrophilic polymer being the same as in the coating of the substrate material; and the step of dipping the substrate material in the solution. A medical device prepared accordingly is also provided.
US10172975B2	Gel-forming agent comprising sulfa agent and chitosan agent and having powdered dosage form The present invention relates to a gel-forming agent comprising a sulfa agent and a chitosan agent and having a powdered dosage form. In addition, the present invention provides a kit comprising the gel-forming agent of the present invention and a method comprising a step for applying the gel-forming agent of the present invention. According to the present invention, a gel-forming agent is provided that demonstrates a therapeutic effect that is more remarkable than that of conventional sulfa agents and chitosan agents alone, and more particularly, a gel-forming agent for protecting an exudative affected area and a gel-forming agent for treating a wound. Namely, by the applying the combination of a sulfa agent and a chitosan agent in the form of a powder, the pH of the affected area is maintained in a range that demonstrates a therapeutic effect, and antibacterial action of the sulfa agent is demonstrated. In addition, the moist environment at the affected area is suitably maintained for suitable granulation. In addition, as a result of being a powder, the use of a suitable dissipating container enables the gel-forming agent to be dispersed by a person performing treatment without making direct contact with the affected area.
US10172974B2	Antimicrobial polymers In one aspect, compositions are described herein. In some embodiments, a composition described herein comprises the reaction product of (i) an alkoxylated or alkenoxylated citric acid, citrate, or ester of citric acid, and optionally a non-alkoxylated and non-alkenoxylated citric acid, citrate, or ester of citric acid, with (ii) a polyol. Additionally, in some cases, a composition described herein comprises the reaction product of (i) and (ii) above and (iii) one or more additional monomers. In some cases, the composition is cross-linked by the use of one or more oxidants such as sodium periodate (NaIO4) and/or silver nitrate (AgNO3), which can be reduced into a reduced oxidant that provides short-term antimicrobial activity. Such a composition can have both short-term and long-term antibiotic and antifungal activity.
US10172973B2	Surgical adjuncts and medicants for promoting lung function Surgical adjuncts and medicants for promoting lung function are provided. In general, an implantable adjunct can have one or more medicants releasably retained therein that are configured to promote lung function. The adjunct can be configured to be applied to lung tissue in conjunction with surgical staples using a surgical stapler. The one or more medicants can be configured to promote lung function in a variety of ways. For example, the one or more medicants can be effective to increase oxygen concentration. For another example of the one or more medicants being configured to promote lung function, the at least one medicant can be configured to treat contaminants in lung tissue.
US10172968B2	Storage device including target UV illumination ranges Ultraviolet radiation is directed within a storage area formed of a plurality of layers including an outer ultraviolet reflective layer, an inner ultraviolet transparent layer, and a layer located between the outer ultraviolet reflective layer and the inner ultraviolet transparent layer. The refractive index of the layer between the outer ultraviolet reflective layer and the inner ultraviolet transparent layer is less than the refractive index of the inner ultraviolet transparent layer. A set of ultraviolet radiation sources generate ultraviolet radiation directed at a set of items located within the storage area.
US10172961B2	Inhibitors of fusion between viral and cell membranes as well as compositions and methods of using them The present application relates to an inhibitor of fusion between a viral membrane from an enveloped virus and a cell membrane, where the viral membrane comprises a fusion mediating protein including a C-terminal peptide. The inhibitor comprises the C-terminal peptide of the fusion mediating protein from an enveloped virus and tocopherol or a derivative or pharmaceutically acceptable salt thereof attached to the C-terminal peptide. Also disclosed is a pharmaceutical composition including the inhibitor as well as methods of inhibiting viral fusion, blocking viral spread, and preventing or treating viral infection, with the inhibitor or pharmaceutical composition.
US10172948B2	Methods for oxime conjugation to ketone-modified polypeptides The invention provides improved methods to prepare protein conjugates from a ketone-modified protein. In one embodiment, the protein is prepared by linking two free cysteines by reaction with a 1,3-dihaloacetone or similar ketone-containing reactant, linking the sulfur atoms of the two cysteines together. The ketone inserted between the sulfur atoms is then used to form an oxime, thus conjugating the protein to a payload. In another embodiment, two cysteine residues are tied together by reaction with a 1,3-dihaloacetone or similar reactant, and the new ketone is used to form an oxime with a suitable payload molecule, thus conjugating the protein to a payload. The method provides improved reaction conditions for the oxime formation, whereby higher yields and improved product homogeneity are achieved.
US10172941B2	Method for synthesis of silica coated graphene functional hybrid material A process for synthesis of silica coated graphene hybrid material comprising the steps of treating graphene oxide with ammonium ions to provide ammonium-activated graphene oxide; treating the ammonium-activated graphene oxide with a solution comprising silica precursors; and silane coupling agents that comprise functional groups, to provide self-assembly of silica nanoparticles on the surface of the ammonium-activated graphene oxide and covalent bonding between the nanoparticles and the surface to provide silica coated graphene oxide; and grafting of the functional groups on the surface of the silica coated graphene oxide to provide functionalized silica coated graphene oxide; and reducing the functionalized silica coated graphene oxide to provide functionalized silica coated graphene. Silica coated graphene hybrid material obtainable by this process.
US10172937B2	Method of treatment of malignant solid tumors with afucosylated anti-FGFR2IIIb antibodies The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.
US10172935B2	Vaccination in newborns and infants The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in newborns and/or infants, preferably exhibiting an age of not more than 2 years, preferably of not more than 1 year, more preferably of not more than 9 months or even 6 months, wherein the treatment comprises vaccination of the newborn or infant and eliciting an immune response in said newborn or infant. The present invention is furthermore directed to kits and kits of parts comprising such a vaccine and/or its components and to methods applying such a vaccine or kit.
US10172934B2	High titer recombinant influenza viruses with enhanced replication in MDCK or vero cells or eggs The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs.
US10172933B2	Mosaic vaccines for serotype a foot-and-mouth disease virus Synthetic foot-and-mouth disease virus (FMDV) mosaic polypeptides, and nucleic acid molecules encoding the mosaic polypeptides, are described. The mosaic polypeptides have greater T-cell epitope coverage than naturally occurring FMDV polypeptides, and include common FMDV epitopes, but exclude rare FMDV epitopes. When included as part of an FMDV genome, the mosaic polypeptides permit virus replication and assembly into FMDV particles. The mosaic polypeptide and nucleic acid compositions can be used to elicit immune responses that provide protection against a broad range of serotype A FMDV strains.
US10172932B2	Ebola virus disease vaccine taking human replication deficient adenovirus as vector Provided are an Ebola virus envelope glycoprotein (that is GP protein) codon optimized nucleotide sequence, a human replication deficient recombinant adenovirus capable of expressing the nucleotide sequence, and applications in preparing a vaccine for preventing Ebola virus diseases. The nucleotide sequence takes a replication deficient 5 type adenovirus that is lack of E1 and E3 in a combined mode as a vector. HEK293 cells that integrate adenovirus E1 genes serve as a packaging cell line, and carried protective antigenic genes are codon optimized Zaire type Ebola virus Makona strain envelope glycoprotein genes. After the envelope glycoprotein genes are optimized by codon, the expression level in transfection cells is obviously improved.
US10172931B2	Baculovirus display vectors and uses thereof A recombinant baculovirus displaying on its envelop a fusion protein is disclosed. The fusion protein comprises a heterologous antigen, and a C-terminal region of baculovirus envelope GP64 protein, which has at least 100 amino acid residues in length and lacks a B12D5 binding epitope located within the central basic region of the GP64 protein. The genome of the recombinant baculovirus comprises a transgene encoding a fusion protein that comprises a signal peptide, the heterologous antigen, and the C-terminal region of the baculovirus envelope GP64 protein, in which the antigen is located between the signal peptide and the C-terminal region of the GP64 protein. Methods for eliciting an antigen-specific immunogenic response in a subject in need thereof are also disclosed.
US10172929B2	Flavivirus vaccines The invention provides flavivirus vaccines and methods of making and using these vaccines.
US10172927B2	Detection/measurement of malaria infection disease utilizing natural immunity by hemozoin induction, screening of preventative or therapeutic medicine for malaria infection disease, and regulation of natural immunity induction The instant invention is to provide a method for detecting and measuring malaria infection utilizing the induction by hemozoin (HZ); a method for screening a vaccine for malaria infection and a preventative or therapeutic agent for malaria infection using the method for detecting and measuring; and a means for regulating the induction of innate immunity using the HZ, synthetic HZ, or derivatives thereof as an adjuvant or immunostimulant. Malaria infection is detected and measured of by detecting and measuring HZ-induced, TLR9-mediated, and MyD88-dependent innate immune activity. The detection and measurement of malaria infection can be used to diagnose malaria infection. The method for detecting and measuring is also used for screening a vaccine for malaria infection and a preventative or therapeutic agent for malaria infection. Further, HZ, synthetic HZ, or derivatives thereof are used as an adjuvant or immunostimulant to regulate HZ-induced innate immune induction.
US10172926B2	KIF20A epitope peptides for TH1 cells and vaccines containing the same Isolated KIF20A-derived epitope peptides having Th1 cell inducibility are disclosed herein. Such peptides can be recognized by MHC class II molecules and induce Th1 cells. In preferred embodiments, such a peptide of the present invention can promiscuously bind to MHC class II molecules and induce KIF20A-specific cytotoxic T lymphocytes (CTLs) in addition to Th1 cells. Such peptides are thus suitable for use in enhancing immune response in a subject, and accordingly find use in cancer immunotherapy, in particular, as cancer vaccines. Also disclosed herein are polynucleotides that encode any of the aforementioned peptides, APCs and Th1 cells induced by such peptides and methods of induction associated therewith. Pharmaceutical compositions that comprise any of the aforementioned components as active ingredients find use in the treatment and/or prevention of cancers or tumors.
US10172920B2	Sleep apnea treatment Provided herein is technology relating to treating sleep apnea and particularly, but not exclusively, to treating sleep apnea with immunotherapeutics and/or anti-inflammatory drugs such as beta-interferons and glatiramer acetate.
US10172918B2	SorCS1 for the treatment of obesity The present invention relates to SorCS1-like agents, including SorCS1, nucleic acid molecule encoding expression of SorCS1 and fragments thereof, as well as vectors containing said nucleic acid and to cells expressing SorCS1 and said fragments, for the treatment of obesity.
US10172916B2	Methods of treating heart failure with agonists of hypocretin receptor 2 Methods of treating individuals for heart failure are disclosed. In particular, the invention relates to methods of treating individuals for heart failure with agonists of hypocretin receptor 2. The invention further relates to the use of genetic analysis of the single nucleotide polymorphism rs7767652, which resides immediately upstream of the HCRTR2 gene, to identify individuals in need of treatment for heart failure who are predicted to be more responsive to medical intervention.
US10172913B2	Orally disintegrating solid pharmaceutical dosage unit containing a partus control substance An orally disintegrating solid pharmaceutical dosage unit having a weight between 50 and 1,000 mg is disclosed. The dosage unit consists of: (a) 5-100 wt. % of coated particles comprising 50-99 wt. % of a core particle and 1-50 wt. % of a coating that envelops the core particle, said coating consisting of: 0.01-10 wt. % of a partus control substance selected from oxytocin, carbetocin, atosiban and combinations thereof; 5-50 wt. % of buffering agent; 15-80 wt. % of branched glucan; 0-78 wt. % of other pharmaceutically acceptable ingredients; and (b) 0-95 wt. % of one or more pharmaceutically acceptable excipients; the solid dosage unit comprising at least 20 μg of the partus control substance and having a pH buffer range of 3.5-5.7.
US10172910B2	Method of preventing or reducing the incidence of acute urinary retention Methods of preventing or reducing the incidence of acute urinary retention in mammals susceptible to developing acute urinary retention, and methods of reducing the incidence of clinically detected prostate cancer, using compositions containing compounds based on small peptides and a pharmaceutically acceptable carrier, are described. The methods include, but are not limited to, administering the compounds intramuscularly, orally, intravenously, intraprostatically, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier to a mammal in need thereof.
US10172909B2	Neuropeptide analogs, compositions, and methods for treating pain Neuropeptide analogs and compositions including neuropeptide analogs are described herein. Also provided are methods of producing and using the neuropeptide analogs and compositions including one or more neuropeptide analogs.
US10172905B1	Treatment of protein degradation disorders The invention relates to methods of treating protein degradation disorders, such cellular proliferative disorders (e.g., cancer) and protein deposition disorders (e.g., neurodegenerative disorders). The invention provides methods and pharmaceutical compositions for treating these diseases using aggresome inhibitors or combinations of aggresome inhibitors and proteasome inhibitors. The invention further relates to methods and pharmaceutical compositions for treating multiple myeloma. New HDAC/TDAC inhibitors and aggresome inhibitors are also provided as well as synthetic methodologies for preparing these compounds.
US10172904B2	Herbal formulations A formulation comprising a variety of Chinese herbs is disclosed for the treatment of cancer and side effects associated with the treatment of cancer.
US10172903B2	Composition comprising scirpusin A and scirpusin B and anti-obesity potential thereof Disclosed are methods of managing hypercholesterolemia using a composition of matter comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes.
US10172900B2	Composition with improved bioavailabilty of saponin and method for improving the bioavailability of saponin The present invention relates to a ginseng mixed composition with improved bioavailability of saponin. Further, the present invention relates to a method for improving saponin bioavailability of a subject comprising: administering to the subject an effective amount of at least one extract selected from a Schizandra chinensis extract and a Liriope platyphylla extract that improves saponin bioavailability in the subject.
US10172899B2	Composition for preventing, treating and improving of voiding dysfunction comprising extract from Piper longum L The present invention relates to a pharmaceutical composition for preventing or treating voiding dysfunction and a health functional food for preventing or improving of voiding dysfunction, comprising extract of Piper Longum L. as an active ingredient. The extract of Piper Longum L. according to the present invention is not only harmless, but also has outstanding effects of preventing, treating and improving voiding dysfunction by being involved in various mechanisms related to voiding dysfunction simultaneously so that it may increase a micturition interval, decrease a micturition pressure, increase a bladder capacity, inhibit detrusor contraction and induce relaxation of detrusor.
US10172897B2	Enhanced smokable therapeutic cannabis product and method for making same An enhanced smokable cannabis-based product produced by separating hash resin from plant material of the cannabis plant, pressing the hash resin to expel oil, leaving spent hash resin, extracting further cannabinoids from the spent hash resin using MCT oil, enriching the extracted oil with a formulation comprising at least purified-myrcene, and spraying the enriched oil onto dried smokable cannabis plant matter.
US10172895B2	Pharmaceutical composition containing Sceptridium japonicum extract for preventing or treating stroke or degenerative brain diseases The present invention provides a pharmaceutical composition containing a Sceptridium japonicum extract, as an active ingredient, for preventing or treating stroke or degenerative brain diseases. The Sceptridium japonicum extract of the present invention has a protective effect on cranial nerves so as to exhibit a functional effect of preventing or treating stroke or various degenerative brain diseases.
US10172894B2	RNA viruses for immunovirotherapy The present invention relates to a recombinant virus of the family Paramyxoviridae, comprising at least one expressible polynucleotide encoding a multispecific binding polypeptide, said multispecific binding polypeptide comprising a first binding domain binding to a surface molecule of an immune cell with antitumor activity, preferably a lymphocyte, more preferably a T cell or a dendritic cell, and a second binding domain binding to a tumor-associated antigen; to a polynucleotide encoding the same, and to a kit comprising the same. Moreover, the present invention relates to a method for treating cancer in a subject afflicted with cancer, comprising contacting said subject with a recombinant virus of the family Paramyxoviridae of the invention, and thereby, treating cancer in a subject afflicted with cancer.
US10172892B2	Strains and methods for energy partitioning in ruminants Described are strains including Enterococcus faecium strain 8G-1 (NRRL B-50173), Enterococcus faecium strain 8G-73 (NRRL B-50172), Bacillus pumilus strain 8G-134 (NRRL B-50174) and strains having all of the identifying characteristics of each of these strains. One or more of the strains can be used to reduce negative energy balance in a ruminant. They can also be used to improve other measures of ruminant health and/or performance. Methods of using the strains, alone and in combination, are described. Methods of making the strains are also provided.
US10172891B2	Tissue repair material derived from fish skin and manufacturing method thereof A tissue repair material derived from fish skin and manufacturing method thereof is applied to provide the tissue repair material suitable for use as a patch, a cover, a carrier, a scaffold, an implant or a reagent in various tissues. The tissue repair material has collagens to improve the wounded tissue repair, and has particular characters for desired tissue repair application. Furthermore, so far the factors of the terrestrial animal transmitted disease (caused by virus) do not survive on the tissue repair material derived from fish skin.
US10172889B2	Method for producing adult liver progenitor cells Novel adult liver progenitor cells (called H2Stem Cells) have been have been characterized on the basis of a series of biological activities and markers. Methods for producing H2Stem Cells allow providing such cells in the form of adherent cells and three-dimensional cell clusters in suspension that can be differentiated into cells having strong liver-specific activities and/or that can be used for treating liver diseases or for evaluating the efficacy, the metabolism, and/or toxicity of a compound.
US10172888B2	Enhanced stem cell composition The invention provides improved methods for cell therapy. In particular, the invention provides therapeutic compositions of enhanced hematopoietic stem and progenitor cells having improved engraftment and homing properties, and methods of making the therapeutic compositions. The invention further provides methods of improving the efficacy of hematopoietic stem and progenitor cell transplantation including transplanting the therapeutic composition to subjects in need of hematopoietic system reconstitution.
US10172886B2	Cell The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising: (i) an antigen-binding domain; (ii) a spacer (iii) a trans-membrane domain; and (iv) an endodomain wherein the antigen binding domains of the first and second CARs bind to different antigens, wherein the spacer of the first CAR is different to the spacer of the second CAR and wherein one of the first or second CARs is an activating CAR comprising an activating endodomain and the other CAR is an inhibitory CAR comprising a ligation-off inhibitory endodomain.
US10172884B2	Dialysis solutions comprising organic esters of phosphoric acid This document relates to bi-carbonate-buffered dialysis solutions with physiological phosphate content and increased stability. The solutions include an organic ester of phosphoric acid, calcium ions and/or magnesium ions, and optionally additional electrolytes, buffers and glucose in physiologically effective concentrations.
US10172883B2	Methods and compositions for treating and/or inhibiting toxins using copper-containing compounds The invention described herein is directed to copper-containing compounds for the treatment of toxin exposure (including pore-forming toxin exposure) in a subject in need thereof. The invention is further directed to methods of treating toxin exposure in a subject in need thereof.
US10172882B2	Pharmaceutical compositions comprising ferric citrate and methods for the production thereof The present invention relates to a pharmaceutical composition comprising granules which include an inert core coated with ferric citrate. The present invention also provides methods of manufacture thereof and methods of use thereof.
US10172872B2	Treatment of otitis media with retroauricular injection of an anti-inflammatory drug The present invention relates to the treatment of otitis media, in particularly secretory otitis media, with an anti-inflammatory drug such as a steroid or a non-steroid anti-inflammatory drug, wherein said anti-inflammatory drug is formulated as a depot formulation for retroauricular injection.
US10172869B2	Progesterone receptor modulators for use in the therapy of uterine fibroids The present invention relates to a long-term therapy including repeated treatment courses of ulipristal acetate or any metabolite thereof for treating uterine fibroids. The present invention also relates to a combined therapy applying ulipristal acetate with a progestin in order to improve the currently used treatment for uterine fibroids.
US10172868B2	Substituted quinazolines for inhibiting kinase activity Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
US10172867B2	Afobazole nanoparticles formulation for enhanced therapeutics A novel nanoparticle drug composition and method of use thereof is presented herein. The nanoparticle drug composition is comprised of at least one nanoparticle carrier, formed from the conjugation of PLGA and PEG, which encapsulates a drug such as afobazole and its derivatives, in a pharmaceutically acceptable carrier. The nanoparticle drug composition may be used to treat various diseases of the central nervous system involving excessive neuronal activity and inflammation such as stroke, Alzheimer's disease and anxiety.
US10172866B2	Substituted 2,3-dihydro-1H-inden-1-one Retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related orphan nuclear receptor γt (RORγt)/RORγ. The compounds of the present invention are useful for modulating RORγt)/RORγ activity and for treating diseases or conditions mediated by RORγt)/RORγ such as for example, disease states associated with immunopathology of human autoimmune diseases such as Multiple Sclerosis (MS), Rheumatoid Arthritis (RA), Inflammatory Colitis, Psoriasis, COPD, Pain, Obesity, Diabetes, Dyslipidemia, Osteoporosis, Asthma, Neurodegenerative diseases and Cancer.
US10172862B2	Imipridones for gliomas Imipridones selectively modulate Class A G protein-coupled receptors (GPCRs), such as the D2-like subfamily of dopamine receptors, and are useful for treating conditions and disorders in need of such modulation, such as cancers. Specifically, the cancer is a midline glioma, a cancer having a histone H3 mutation, or both. In addition, methods of identifying whether a subject having these conditions, is likely to be responsive to a treatment regimen, such as imipridone administration, are provided. Furthermore, methods of assessing the effectiveness of a treatment regimen, such as imipridone administration, monitoring, or providing a prognosis for a subject with these condition are also provided.
US10172861B2	Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate A novel crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, pharmaceutical compositions containing said crystalline form and the use of said crystalline form in the treatment of pain, cancer, inflammation, neurodegenerative disease or Trypanosoma cruzi infection are disclosed. In some embodiments, the novel crystalline form comprises a stable polymorph of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate. The present invention is further directed to a process for the preparation of the novel crystalline form.
US10172858B2	Combination pharmaceutical compositions and uses thereof The present invention provides for methods and pharmaceutical compositions for treating proliferative disorders. In one aspect, the method comprises administration of two cell-cycle suppressors having a synergistic effect. In another aspect, two cell-cycle suppressors having a synergistic effect are provided in a pharmaceutical composition.
US10172854B2	Compositions and methods for treating mitochondrial diseases The invention described herein relates to methods for treating mitochondrial diseases. In particular, the invention relates to methods for treating mitochondrial diseases by administering therapeutically effective amounts of one or more tetracyclic pyrazinoindoles, and/or pharmaceutically acceptable salts thereof.
US10172846B2	HCV NS-3 serine protease inhibitors Methods drawn to peptidomimetic compounds which inhibit the NS3 protease of the hepatitis C virus (HCV), are described. The compounds have the formula (VI) where the variable definitions are as provided in the specification. The compounds comprise a carbocyclic P2 unit in conjunction with a novel linkage to those portions of the inhibitor more distal to the nominal cleavage site of the native substrate, which linkage reverses the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site.
US10172845B2	Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Provided herein are compounds of the Formula I: or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
US10172843B2	Piperidine derivatives The invention relates to a compound of formula (I) wherein A1, A2 and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
US10172837B2	Insulin sensitisers and methods of treatment The present invention relates generally to the field of therapy. The invention particularly relates to insulin sensitizers and methods of regulating glucose homeostasis and to the therapeutic or prophylactic treatment of diseases and associated conditions, in which impaired glucose uptake due to insulin resistance is involved or implicated, such as diabetes, syndrome X, hyperglycaemia, vascular disease and kidney disease. The present invention further relates to compounds and agents and compositions thereof for use in the treatment methods.
US10172833B2	Sublingual ondansetron spray The invention is directed to sublingual spray formulations containing ondansetron, a pharmaceutically acceptable salt thereof, and a solvent consisting of ethanol and glycerin, suitable for administration to humans, and methods for treatment with sublingual formulations.
US10172831B2	Catalytic scavengers of organophosphates to potentiate butyrylcholinesterase (hBChE) as a catalytic bioscavenger and methods for making and using them Provided are N-alkyl imidazole 2-aldoximes, including cationic imidazolium and uncharged tertiary imidazole aldoximes, and compositions and methods for making and using them, including methods for reactivating human butyrylcholinesterase (hBChE) or acetylcholinesterase (hAChE) inhibited by organophosphate (OP). By administration of a composition of the invention, the inactive or conjugated hBChE-OP or hAChE-OP is reactivated and the catalytic cycle of turnover and inactivation of the OP is completed; and in alternative embodiments, secondary mechanisms of reversible protection of hBChE and hAChE from irreversible inactivation by OPs and reactivation of tissue AChE also contribute to overall efficacy.
US10172830B2	Pyrazolone compounds having human neutrophil elastase inhibitory properties Pyrazolone derivatives of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for the treatment of diseases or conditions in which HNE is implicated.
US10172827B2	Pro-neurogenic compounds This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death.
US10172812B2	Compounds and methods for treating muscular dystrophy and other disorders The present invention provides compositions and methods of their use in treating dystroglycanopathy, muscular dystrophy and other disorders.
US10172806B2	Pharmaceutical composition having abuse deterrent properties An object of the present invention is to provide a pharmaceutical composition having abuse deterrent properties and thereby prevent the abuse of a pharmacologically active component by an abuser (abuse through snorting, abuse through injection, or abuse through snorting or injection of a temporarily extracted drug). The present invention provides a pharmaceutical composition having abuse deterrent properties that possesses both a physical barrier and a chemical barrier to being abused by an abuser, a method for producing the same and a method for using the same.
US10172805B2	Prolonged release formulations comprising an 2-oxo-1-pyrrolidine derivative The present invention relates to a pharmaceutical composition comprising Levetiracetam, Brivaracetam or Seletracetam as active ingredient, the invention relates specifically to a prolonged release formulation.
US10172803B2	Hard capsule formulation A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.
US10172802B2	Oral pharmaceutical dosage forms of budesonide The present invention relates to novel oral sustained release pharmaceutical dosage forms for delivery of budesonide to the lower gastrointestinal tract for the treatment of Crohn's disease.
US10172800B2	Controlled release dosage form with enhanced pharmacokinetics The present invention provides a simple and improved dosage form that is capable of providing a controlled release of GABAB receptor agonist contained in the core thereof. The invention also provides methods of administering the dosage form and of treating conditions that are therapeutically responsive to GABAB receptor agonist.
US10172784B2	Bioactive compositons having skin anti aging activity The present invention relates to bioactive compositions comprising blends of camellia and feverfew serum fractions and/or kelp and parsley serum fractions.
US10172782B2	Compositions and methods for treating hair Disclosed herein are compositions and methods for styling hair comprising at least two latex polymers, wherein at least one latex polymer is a film-forming polymer; at least one aminofunctional silicone; at least one amphoteric surfactant; at least one alkylpolyglucoside; at least one anionic thickening agent; and water; wherein the at least two latex polymers are present in a combined amount ranging from about 0.1% to about 30% by weight, relative to the weight of the composition.
US10172779B2	Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same A copolymer in which from 45 to 60% by mass of all monomer units are unsaturated monomers having a specific carbosiloxane dendrimer structure is disclosed, along with a composition, a cosmetic raw material, and a cosmetic containing the copolymer. The copolymer has excellent physical properties, including compatibility with other cosmetic raw materials, e.g. hardly soluble ultraviolet absorbers, and is capable of improving the compounding stability of cosmetics. The copolymer imparts cosmetics with good water resistance, sebum resistance, luster, tactile sensation, and adhesiveness to the hair or skin.
US10172777B2	Phytospingosine derivative and composition containing same The present invention relates to a phytospingosine derivative generated by a condensation reaction of phytospingosine and maltose or lactose, which is an aldose-based disaccharide, and to a composition containing the same. The phytospingosine derivative of the present invention has high solubility in water compared with phytospingosine, is easy to formulate since the stabilization problem in a solution is solved, and maintains or further enhances the antibacterial effect of phytospingosine.

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