最新美国发明专利第2018-08-14期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US10047278B1	Fracturing fluid composition and a method of fracturing a subterranean formation using the same A fracturing fluid composition that includes a chelating agent, e.g. GLDA, and a polymeric additive comprising a copolymer of acrylamido-tert-butyl sulfonate and hydrolyzed polyacrylamide diluted in an aqueous base fluid, e.g. seawater, and a method of fracking a geological formation using the fracturing fluid composition. Various embodiments of the fracturing fluid composition and the method of fracking are also provided.
US10047275B2	Hydrocarbon recovery using complex water and carbon dioxide emulsions In one aspect, a method of recovering hydrocarbons from a subterranean zone includes flowing carbon dioxide in a first state into the subterranean zone including hydrocarbons, wherein a density of the carbon dioxide in the first state is greater than a density of carbon dioxide in a gaseous state, and recovering at least a portion of the hydrocarbons in the subterranean zone in response to flowing carbon dioxide in the first state into the subterranean zone.
US10047273B2	Beta-amino ester gas hydrate inhibitors Disclosed herein are beta-amino ester surfactant compounds and compositions useful in applications relating to inhibition of gas hydrate agglomerates in the production, transportation, storage, and separation of crude oil and natural gas. Also disclosed herein are methods of using the compounds and compositions as gas hydrate inhibitors, particularly in applications relating to the production, transportation, storage, and separation of crude oil and natural gas.
US10047271B2	Bifunctional anti-deposit and anti-corrosion additives The invention concerns bifunctional compositions usable in the field of extraction of hydrocarbons, oil and/or gas, said compositions being homogeneous, clear and stable and comprising at least one anti-mineral-deposit additive, at least one corrosion inhibitor, and at least one agent for compatibilizing between the anti-mineral-deposit additive and the corrosion inhibitor.
US10047269B2	Treatment fluids comprising finger millet and methods of use The present disclosure relates to a well treatment fluid comprising finger millet, a breaker package, and a continuous aqueous phase. The present disclosure also relates to a method for treating at least a portion of a subterranean well comprising forming an aqueous treatment fluid comprising (i) finger millet, (ii) a breaker package comprising at least one breaker, and (iii) a continuous aqueous phase; and introducing the treatment fluid into at least a portion of the subterranean well.
US10047267B2	Strontium carbonate bridging materials and methods for making and using same Drilling fluids were developed including a base fluid, a weighting agent and/or a bridging agent, and a thickening agent, where the weighting agent and/or the bridging agent includes a particulate strontium carbonate having a desired distribution, for weighting agents, the distribution includes particles between 2μ and 5000μ and for bridging agents, the distribution is constructed from particles having specific sizes. Methods making and using the drilling fluids were also discovered.
US10047266B1	Energy-saving and environment-friendly anti-freezing solution for water system engine The invention discloses an energy-saving and environment-friendly anti-freezing solution for a water system engine, which includes calcium chloride anti-freezing solution and alcohol-type anti-freezing solution. N-methyl pyrrolidone and allyl glycidyl ether are added into the calcium chloride anti-freezing solution and the alcohol-type anti-freezing solution. With the energy-saving and environment-friendly anti-freezing solution for the water system engine, when the water system engine gets into the best operating state, rapid cooling down and heat dissipation can be achieved. When the temperature is low, rapid heating-up can be achieved. Thus, the temperature of the engine is kept in constant and stable state, so that the engine can perform the combustion sufficiently to convert the thermal energy into power. The purposes of saving oil, improving power, reducing emission, saving energy, and protecting the environment are actually achieved.
US10047265B2	Rare earth regenerator material particle, rare earth regenerator material particle group, and cold head, superconducting magnet, examination apparatus, and cryopump using the same A rare earth regenerator material particle and a regenerator material particle group having a high long-term reliability, and a superconducting magnet, an examination apparatus, a cryopump and the like using the same are provided. A rare earth regenerator material particle contains a rare earth element as a constituent component, and in the particle, a peak indicating a carbon component is detected in a surface region by an X-ray photoelectron spectroscopy analysis.
US10047262B2	Cerium oxide abrasive, method for producing cerium oxide abrasive, and polishing method An object of the present invention is to provide a cerium oxide abrasive material containing cerium oxide abrasive particles prepared by a synthetic method using an aqueous solution of a salt of a rare earth element and a precipitant, the cerium oxide abrasive particles having a spherical shape and high polishing performance (polishing rate and polishing precision of the polished surface), a method for producing the cerium oxide abrasive material, and a polishing method. The cerium oxide abrasive material according to the present invention comprises spherical cerium oxide abrasive particles prepared by a synthetic method using an aqueous solution of a salt of a rare earth element and a precipitant, wherein the cerium oxide abrasive particles have a spherical shape having an average aspect ratio within the range of 1.00 to 1.15.
US10047261B2	Elastomeric seal The present invention provides a seal comprising an elastomeric composite, said composite comprising an elastomeric polymer and a negative thermal expansion (NTE) filler, the NTE filler has a coefficient of thermal expansion (CTE) lower than −6×10-6 K-1 within a temperature range of 220-293 K and is present in an amount of 0.01-50 volume % based on the total volume of the elastomeric composite at 20° C.
US10047254B2	Curable composite manufacturing adhesive A curable adhesive that is modified to allow spray application and polymerization seamlessly during the process of epoxy resin vacuum infusion.
US10047250B2	Adhesive composition with glass spheres A new adhesive composition containing glass beads and having unique properties in automotive related applications. The method of making such new adhesive composition.
US10047247B2	Composition and method for controlling the wettability of surfaces The present invention relates to a composition comprising hedge-hog shaped particles, at least one binder, and at least one hydrophobizing agent and/or at least one hydrophilizing agent, a method for controlling the wettability of substrate surfaces using these compositions, as well as a material comprising these compositions.
US10047245B2	Non-fluorinated and partially fluorinated polymers A polymer composition with (A) a first poly(meth)acrylate polymer or urethane polymer; and (B) a second poly(meth)acrylate polymer or urethane polymer which has a residue X incorporated therein, where X is the residue of a cyclic or acyclic sugar alcohol which is substituted with at least one —R1; —C(O)R1; —(CH2CH2O)n(CH(CH3)CH2O)mR2; —(CH2CH2O)n(CH(CH3)CH2O)mC(O)R1; or mixtures thereof; where the cyclic or acyclic sugar alcohol is selected from a saccharide, reduced sugar, aminosaccharide, aldonic acid, or aldonic acid lactone; wherein each n is independently 0 to 20; each m is independently 0 to 20; m+n is greater than 0; each R1 is independently a linear or branched alkyl group having 5 to 29 carbons optionally comprising at least 1 unsaturated bond; and each R2 is independently —H, a linear or branched alkyl group having 6 to 30 carbons optionally comprising at least 1 unsaturated bond, or mixtures thereof.
US10047239B2	Organic solvent dispersion of titanium oxide particles and method for producing same The invention provides an organic solvent dispersion of titanium oxide particles in a content of 10% by weight or more in an organic solvent except methanol and ethanol, wherein the titanium oxide particles are surface-treated with a surface treating agent comprising a silane coupling agent having the general formula (I) (RO)n—Si—X4-n (I) wherein R is an alkyl group having carbon atoms of 1-4, n is 2 or 3, X is an alkyl, a fluoroalkyl, a vinyl or a (meth)acryloyloxyalkyl group, and 12-hydroxystearic acid, and wherein the titanium oxide particles in the organic solvent have a D50 in a range of 1 to 30 nm, and wherein the organic solvent dispersion has a transmittance of 2% or more at a wavelength of 500 nm and a transmittance of 70% or more at a wavelength of 800 nm, a viscosity of 10 mPa·s or less at a temperature of 25° C. immediately after production while the increase in the viscosity is 40 mPa·s or less seven days after production as compared to that of the dispersion immediately after production.
US10047232B2	Waterborne coating composition with improved open time The invention relates to an aqueous coating composition comprising a film-forming first polymer and a second polymer for improving the open time, the wet edge time, adhesion and/or hardness of the resulting coating. The invention further relates to said novel second polymer, its use in coating compositions for improving the open time and coalescence. The water soluble second polymer is an addition polymer comprising 25-95 wt % specific non-ionic hydrophilic monomers A and 5-75 wt % of hydrophobic monomers B which second polymer is sparingly water soluble and a solution of only said second polymer in water has a substantially Newtonian flow behavior in a wide solid contents range.
US10047225B2	Styryl sulfide dyes Disclosed are styryl dyes of formula wherein R1, R2, R3, R′1, R′2 and R′3 independently of each other are hydrogen; —NH(CO)—C1-C5alkyl; —N(C1-C5alkyl)(C1-C5alkyl-CN); C1-C6alkoxy; a heterocyclic radical; or R1 and R2 or R′1 and R′2 together form a 5- to 10-membered, monocyclic, carbocyclic or heterocyclic ring; wherein at least one of R1, R2, R3, R′1, R′2 and R′3 is different from hydrogen; Q and Q′ independently from each other are the direct bond; —C(O)—; —C(O)O—; —OCO—; —N(R4)—; —C(O)N(R6)—; or —(R6)NC(O)—; and R4, R5 and R6 independently from each other are hydrogen; C1-C14alkyl; C2-C14alkenyl; C6-C12aryl; C6-C12aryl-C1-C10alkyl; or C1-C10alkyl(C5-C12aryl); X and X′ are —(CH2)m—; Y1 and Y2 independently from each other are C1-C10alkylene; C5-C10cycloalkylene; C5-C12arylene; or C5-C12arylene-(C1-C10alkylene); An− is an anion; m is a number from 1 to 8; n is 0, or 1; and p is 0, or 1.
US10047221B2	Flocculant composition for dewatering solids laden slurries Flocculant compositions containing a cellulosic compound, a superabsorbant polymer, and a flocculant, are useful for preventing the formation of an aqueous phase during the shipping of fly ash slurries.
US10047219B2	Polyolefin-based resin composition Provided is a polyolefin-based resin composition capable of obtaining a molded product having a high modulus of elongation and a low coefficient of linear expansion. The polyolefin-based resin composition includes a polyolefin-based resin containing either one or both of an acid-modified polyolefin-based resin and a polyolefin-based resin with a hydroxyl group, and flaked graphite. The flaked graphite is uniformly dispersed in the polyolefin-based resin. As a result, a molded product formed by using the polyolefin-based resin composition has excellent mechanical strength such as a high modulus of elongation, a low coefficient of linear expansion, and high dimensional stability, and can be used for various applications such as a material that is suitable for use as the exterior panels of automobiles or a steel sheet replacement material.
US10047217B2	Ethylene-based polymer compositions, and articles prepared from the same The invention provides a composition comprising a first composition, wherein the first composition comprises a first ethylene-based polymer and a second ethylene-based polymer, and wherein the first composition has a high load melt index (I21) less than 17, a density greater than, or equal to, 0.952 g/cm3, a molecular weight distribution MWD (conv), defined as the ratio of the weight average molecular weight to the number average molecular weight (Mw (conv)/Mn (conv)), greater than, or equal to, 11; and a viscosity ratio, η(0.01 s−1)/η(100 s−1) at 190° C., greater than, or equal to, 60.
US10047213B2	Method of curing thermosetting resin composition, thermosetting resin composition, and PREPREG, metal-clad laminate, resin sheet, printed-wiring board, and sealing material in which thermosetting resin composition is used A thermosetting resin composition includes a thermosetting resin containing a benzoxazine compound, and a curing accelerator containing a triazine thiol compound. The thermosetting resin contains 0.4 or less equivalents of an epoxy resin relative to one equivalent of the benzoxazine compound.
US10047210B2	Bio-based binders including carbohydrates and a pre-reacted product of an alcohol or polyol and a monomeric or polymeric polycarboxylic acid An environmentally friendly, formaldehyde-free, aqueous binder composition that includes a carbohydrate, a crosslinking agent, and a pre-reacted product of an alcohol or polyol and monomeric or polymeric polycarboxylic acid or polyglycerol is provided. The pre-reacted product may include glycerol and esters of citric acid such a monoglyceryl citrate, diglyceryl citrate, and triglyceryl citrate as well as other higher molecular weight citric acid-based esters. The inclusion of the pre-reacted product in the binder composition helps to speed the crosslinking reaction, induces faster water evaporation, decreases the viscosity of the binder, helps to reduce the amount of water needed for application of the binder, decreases tackiness, and helps to achieve a maximum vertical expansion of the insulation pack in the transfer zone. The binder composition may be used in the formation of insulation materials and non-woven chopped strand mats.
US10047207B2	Microporous polyimide sponge and method for producing the same Disclosed is a net-shaped polyimide sponge. The polyimide sponge has a stack structure of nets. Also disclosed is a method for producing a polyimide sponge. The method enables the production of a polyimide sponge in a simple manner compared to conventional methods based on wet or dry phase inversion techniques using porogens.
US10047202B2	Resin-containing sheet, and structure and wiring board using same Provided are: a resin-containing sheet in which not only the mechanical strength of a cellulose nanofiber nonwoven fabric but also the flexural resistance of a substrate are improved; and a structure and a wiring board which include the same. The resin-containing sheet includes: a specific cellulose nanofiber nonwoven fabric (11); a fixing agent (2) which fixes together fibers (1) in the cellulose nanofiber nonwoven fabric (11); and a resin (3) which is in contact with the cellulose nanofiber nonwoven fabric (11) and the fixing agent (2), wherein the storage modulus of the fixing agent (2) is higher than that of the resin (3). The structure is obtained by tightly adhering the resin-containing sheet to a substrate. The wiring board includes this structure.
US10047201B2	Method of producing sliding material for weather strips PP, an EPDM prior to crosslinking, and PE particles are fed into a twin screw extruder and melt-kneaded so that the EPDM is dynamically crosslinked, whereby a sliding material for weather strips formed of an olefin-based TPV in which the PE particles are dispersed is produced. The amount of the PE particles blended is 10 parts by mass to 90 parts by mass with respect to 100 parts by mass of the total amount of the PP and the EPDM. It is preferable that the PE particles have an average particle diameter of 30 μm to 200 μm before the feeding, and are micronized by the melt kneading to have an average particle diameter of 10 μm to 50 μm in the produced sliding material for weather strips.
US10047200B2	Dendritic polymer, dendritic polymer monomer, and hyperbranched copolymer A dendritic polymer, a dendritic polymer monomer, and a hyperbranched copolymer are described. The dendritic polymer monomer has a structure denoted by Z′-(Q)n-Y, wherein Z′ represents a structure denoted by the following formula (a) and/or formula (b), Q represents a dendritic constitutional repeating unit of the dendritic polymer monomer, n represents the generation number of the dendritic polymer monomer, and is an integer within a range of 2-6, Y represents a group that contains SO3− and COO−, R14-R16 can be identical to or different from each other, and are H or C1-C5 alkyl respectively. The monomer can be used as a copolymerizable monomer for preparing a hyperbranched polymer applicable to oil fields, the obtained hyperbranched polymer can be used as an inhibiting filtrate reducer for drilling fluid, flocculating agent, encapsulating agent, heat-resistant and salinity-resistant polymer flooding agent, and thickening agent for fracturing liquid, etc.
US10047195B2	Monomers bearing associative groups for the synthesis of supramolecular polycondensates The present invention relates to the use of monomers bearing associative groups in order to manufacture a supramolecular polycondensate, to certain of these monomers, to a process for manufacturing a supramolecular polycondensate, to the polycondensate obtained, and also to an article or a composition incorporating same. The associative groups may be, for example, imidazolidone, urea or triazole groups.
US10047188B2	High strength polyurethane foam compositions and methods Disclosed are high strength polyurethane foam compositions and methods of making them. In one aspect, the inventive polyurethane foams include strength enhancing additives comprising one or more polycarbonate polyols derived from the copolymerization of CO2 and one or more epoxides. In one aspect, the inventive methods include the step of substituting a portion of the polyether polyol in the B-side of a foam formulation with one or more polycarbonate polyols derived from the copolymerization of CO2 and one or more epoxides.
US10047183B2	Photoreactive copolymer and alignment layer comprising the same There are provided a photoreactive copolymer and an alignment layer comprising the same, and more particularly, to a photoreactive copolymer including a copolymer of two different kinds of monomers, and an alignment layer comprising the same. The photoreactive copolymer according to the present invention may have excellent liquid crystal alignment property and alignment speed, easily change an alignment direction depending on a polarization direction, and have excellent solubility to an organic solvent, such that the photoreactive copolymer may be used in various fields such as a liquid crystal device, and the like.
US10047181B2	Tetrafluoroethylene copolymers The invention pertains to a tetrafluoroethylene (TFE) copolymer comprising recurring units derived from at least one perfluoroalkyl(oxy)vinylether of formula CF2═CF—O—Rf, wherein Rf is a C1-C6 perfluoroalkyl radical possibly comprising one or more ethereal oxygen atoms [monomer (F)], in an amount of 0.005 to 0.025% moles, with respect to the total moles of the copolymer, wherein a particular relation between monomer content and amorphous index is satisfied, and to a process for its manufacture by emulsion polymerization in the presence of certain cyclic surfactants.
US10047179B2	Heat-resistant styrene copolymer and styrene resin composition comprising the same Provided is a styrene resin composition including α-methyl styrene, acrylonitrile and t-butyl methacrylate, and having an improved conversion rate while maintaining excellent mechanical and chemical properties, a styrene resin composition including the same, and a styrene resin molded product manufactured therefrom. Accordingly, the heat-resistant styrene copolymer is effective in improving a conversion rate without deformation and mechanical and chemical property decline of the material itself, and as a result, commercialization may be readily accomplished due to enhanced productivity. In addition, the styrene resin molded product manufactured from the styrene resin composition according to the present invention includes the heat-resistant styrene copolymer as a matrix copolymer, and therefore, has excellent impact strength, tensile strength, tensile elongation and flowability while having high heat resistance.
US10047177B2	Process for preparing halogenated polymer having reduced residual acidity and yellowness index of 3.5 and below The present disclosure provides a process for the reduction of residual acidity of halogenated polymer. The process involves treating the halogenated polymer to a physical process such as rotary vacuum drying and then neutralizing the treated halogenated polymer with alkaline metal salt solutions. The process requires less quantity of an economic neutralizing agent/base during chemical treatment, thus improving process economy without prejudicing quality of the final halogenated polymer.
US10047171B2	Amphiphilic bioconjugates obtained from xylan derivatives The present invention concerns a compound of formula (I): wherein: —n is an integer comprised between 1 and 7; —X1 is in particular a radical of formula —CH2—S—(CH2)k—S—; —A1 is in particular a linear or branched alkylene radical comprising from 2 to 30 carbon atoms, and —X2 is in particular an alkoxy group of formula ORa, wherein Ra is a linear or branched alkyl group comprising from 1 to 10 carbon atoms.
US10047168B2	Process for the preparation of purified β-(1,3)-D-glucans There is provided a process for the preparation of purified β-(1,3)-D-glucans, comprising the steps of providing an aqueous β-(1,3)-D-glucan initial solution having a pH of above 11.0, filtering the aqueous β-(1,3)-D-glucan initial solution to obtain a β-(1,3)-D-glucan containing filtrate, adjusting the pH of the β-(1,3)-D-glucan containing filtrate with an acid to a pH of below 5.0 to obtain an acidic β-(1,3)-D-glucan solution, and heating the acidic β-(1,3)-D-glucan solution to a temperature in the range of 60 to 160° C.
US10047165B2	Compositions for inhibiting MASP-2 dependent complement activation The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
US10047162B2	Sequence dependent aggregation Herein is reported a method for reducing the aggregation of an immunoglobulin in solution comprising the steps of i) comparing the amino acid sequence of the fourth framework region of the heavy chain of an antibody with a reference or germline sequence and determining whether one or more threonine residues and/or serine residues have been replaced by a different amino acid residue, and ii) modifying the amino acid sequence of the immunoglobulin by reverting the exchanged threonine residues and/or serine residues back to threonine or serine of the reference or germline sequence and thereby reducing the aggregation of an immunoglobulin in solution.
US10047160B2	Anti-EGFRvIII antibodies and uses thereof The present invention provides antibodies that bind to the class III variant of EGFR (EGFRvIII) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human EGFRvIII with high affinity. The antibodies of the invention may be fully human antibodies. The invention includes anti-EGFRvIII antibodies conjugated to a cytotoxic agent, radionuclide, or other moiety detrimental to cell growth or proliferation. The antibodies of the invention are useful for the treatment of various cancers.
US10047159B2	Bispecific single chain antibodies with specificity for high molecular weight target antigens The present invention provides a method for the selection of bispecific single chain antibodies comprising a first binding domain capable of binding to an epitope of CD3 and a second binding domain capable of binding to the extracellular do main cell surface antigens with a high molecular weight extracellular domain. Moreover, the invention provides bispecific single chain antibodies produced by the use of the method of the invention, nucleic acid molecules encoding these antibodies, vectors comprising such nucleic acid molecules and methods for the production of the antibodies. Furthermore, the invention provides pharmaceutical compositions comprising bispecific single chain antibodies of the invention, medical uses of the same and methods for the treatment of diseases comprising the administration of bispecific single chain antibodies of the invention.
US10047156B2	Anti-CXCL1, CXCL7 and CXCL8 antibodies and their applications The invention provides an isolated antibody or a fragment thereof, which is directed to the human chemokines CXCL1, CXCL7 and CXCL8, said antibody or fragment being capable of binding to the human chemokine CXCL1 with an equilibrium dissociation constant (KD) of at most 16 nM, to the human chemokine CXCL7 with an equilibrium dissociation constant (KD) of at most 5 nM and to the human chemokine CXCL8 with an equilibrium dissociation constant (KD) of at most 45 nM, as determined by surface plasmon resonance. The invention also provides some applications of said isolated antibody.
US10047155B2	Antibodies targeting bone morphogenetic protein 9 (BMP9) and methods therefor The present invention relates to isolated antibodies and antigen-binding fragments thereof which bind human BMP9 and compositions and methods of use thereof.
US10047154B2	Angiopoietin-2 specific antibodies and uses thereof An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
US10047150B2	Anti-neublastin antibodies and uses thereof Antibodies and antigen binding fragments that bind to neublastin polypeptides are disclosed. Also disclosed are methods of using the antibodies and antigen binding fragments in assays for detecting the presence or amount of endogenous and/or exogenous neublastin in a sample and in methods of antagonizing neublastin bioactivity.
US10047148B2	Neutralizing GP41 antibodies and their use Monoclonal neutralizing antibodies are disclosed that specifically bind to the HIV-1 gp41 membrane-proximal external region (MPER). Also disclosed are compositions including the disclosed antibodies that specifically bind gp41, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of HIV-1 in a biological sample, or detecting an HIV-1 infection or diagnosing AIDS in a subject. In additional, the broad neutralization breadth of the disclosed antibodies makes them ideal for treating a subject with an HIV infection. Thus, disclosed are methods of treating and/or preventing HIV infection.
US10047147B2	Neutralizing GP41 antibodies and their use Monoclonal neutralizing antibodies are disclosed that specifically bind to the HIV-1 gp41 membrane-proximal external region (MPER). Also disclosed are compositions including the disclosed antibodies that specifically bind gp41, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of HIV-1 in a biological sample, or detecting an HIV-1 infection or diagnosing AIDS in a subject. In additional, the broad neutralization breadth of the disclosed antibodies makes them ideal for treating a subject with an HIV infection. Thus, disclosed are methods of treating and/or preventing HIV infection.
US10047142B2	Factor VIII variants having a decreased cellular uptake The present invention relates to modified coagulation factors. In particular, the present invention relates to modied Factor VIII molecules having decreased cellular uptake.
US10047141B2	Method of manufacturing a protein by perfusion in media with a low amino acid concentration Perfusion media are disclosed providing excellent cell density, titer and product quality for production of a therapeutic protein in a perfusion process.
US10047134B2	Process for expression of recombinant proteins in Pichia pastoris using a fed batch model The present disclosure relates to a comprehensive model for expression of recombinant peptides by Pichia pastoris. The model uses an easily controllable variable called ‘critical nutrient ratio’ for obtaining a right balance between product synthesis and it's degradation during the fermentation process. The extra cellular concentration of precursor could be increased by about 10 folds and the degradation constants could be reduced by about 10-20 folds for intracellular and extracellular cases respectively by controlling critical nutrient ratio and addition of soya flour hydrolysate and EDTA.
US10047131B2	Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10047128B2	Encryption of adeno-associated viruses with enzymatically decoded peptide locks The present invention is a peptide lock that comprises at least one peptide that is genetically encoded into the Adeno-associated virus (AAV) capsid that block biologically active domains on the virus capsid surface. The peptide lock, can be processed by biological enzymes to restore biological behavior of the capsid-displayed domains, thus ‘decoding the lock’ or opening the lock. A method of forming the peptide lock comprises providing at least one peptide, providing an Adeno-associated virus capsid and genetically inserting the at least one peptide into the Adeno-associated virus capsid to block the biologically active domains on the virus capsid surface.
US10047125B2	Peptide having activity to improve skin condition and use thereof A peptide having activity to improve skin condition is described. The peptide exhibits a very excellent effect in improving skin condition by inhibiting MMP2 activity. A composition containing the peptide exhibits excellent biological activities, such as inhibiting collagen decomposition and melanosome migration, and thus can be used in wrinkle reduction, skin regeneration, skin elasticity improvement, anti-skin aging, wound regeneration, acne reduction, skin regeneration or skin whitening. The composition containing the peptide can be used as a pharmaceutical composition for preventing or treating MMP activity-related diseases and inflammation diseases.
US10047122B2	Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use The invention provides novel compounds that may serve as anticancer therapeutics. The compounds of the invention bind to polo-like kinases through the polo-box domain. In certain embodiments, the compounds of the invention are POM-protected peptide derivatives. The use of cationic bis-alkyl his residues in combination with a mono POM-protected phophoryl group results in a peptide possessing an overall neutral charge. The peptide derivatives of the invention have achieved both good efficacy and an enhanced bioavailability. The invention also provides methods of use, compositions, and kits thereof. Further, the invention provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.
US10047120B2	Method for producing a composition for treating a tooth lesion The invention relates to a method for preparing a composition for treating a tooth lesion, said composition comprising peptides that are capable of undergoing self-assembly at a certain pH. The compositions of the invention are highly suitable for being used in the medical field, in particular for remineralizing a tooth lesion such as a subsurface caries lesion.
US10047118B2	C17-aryl substituted betulinic acid analogs Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: These compounds are useful for the treatment of HIV and AIDS.
US10047117B2	Preparation and uses of obeticholic acid The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of obeticholic acid.
US10047116B2	Nanoparticles, process for preparation and use thereof as carrier for amphipatic and hydrophobic molecules in fields of medicine including cancer treatment and food related compounds The present invention regards nanoparticles comprising a sterol and a component derived from Quillaja saponaria Molina selected from quillaja acid and quillaja saponin, which nanoparticles do not comprise a phospholipid. It also relates to a composition comprising the nanoparticles, and the use thereof as adjuvant, especially in vaccines, as carriers for amphipathic or hydrophobic molecules and as agents for treatment of cancer. Further, it regards a method for producing the phospholipid-free nanoparticles, a method for the treatment of cancer and a method for assessing the applicability of the cancer treating method.
US10047114B2	Nucleotide and oligonucleotide prodrugs The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US10047111B2	RNA interference agents for GST-PI gene modulation This invention provides compounds, compositions and methods for modulating the expression of human GST-π using RNA interference. The RNA interference molecules can be used in methods for preventing or treating diseases such as malignant tumor. Provided are a range of siRNA structures, having one or more of nucleotides being modified or chemically-modified. Advantageous structures include siRNAs with 2′-deoxy nucleotides located in the seed region, as well as other nucleotide modifications.
US10047109B2	Ash-free cyclic organic polyol-based reactive porogens and nanoporous ultra low dielectric film by using the same The present disclosure relates to a reactive porogen using cyclic organic polyol and an ultra low dielectric film prepared using the same, and more particularly, to novel cyclic organic polyol as a cyclic organic polyol compound which can be completely pyrolyzed at a temperature of 500° C. or less, does not leave carbon residue during a heat treatment if an end hydroxyl group of the cyclic organic compound is substituted by a functional group of alkylalkoxysilane and then used as a reactive porogen, and is involved in a sol-gel reaction of organic silicate and suppresses phase separation and thus forms pores having a uniform size and has excellent mechanical properties as compared with a porosity, a reactive porogen using the ash-free cyclic organic polyol, and an ultra low dielectric film prepared using the same.
US10047105B2	Gyrase inhibitors Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth. Compounds of Formula (I), are disclosed: Formula (I), wherein Y is N or CH; Z is N or CR5; R5 is H, a substituted or unsubstituted hydrocarbyl residue (1-3C) containing 0-2 heteroatoms selected from O, S and N, or is an inorganic residue; L is O, S, NR7, or CR8R9; R7 is H or C1-3 alkyl; R8 and R9 are each independently H or C1-3 alkyl; R2 is H, a hydrocarbyl residue (1-40C) containing 0-10 heteroatoms selected from O, S and N optionally substituted with an inorganic residue; R4 is H, an inorganic residue, or a hydrocarbyl residue (1-30C) containing 0-12 heteroatoms selected from O, S and N and containing 0-10 inorganic residues, wherein R5 and R4 together may join to form a fused ring; and R6 is selected from the group consisting of H, C1-5 alkyl, C2-5 alkenyl, C2-5 alkynyl, halo C1-5 alkyl, halo C2-5 alkenyl, halo C2-5 alkynyl, C1-5 hydroxyalkyl, C1-5 alkyl chloride, C2-5 alkenyl chloride, and C2-5 alkynyl chloride; or a pharmaceutically-acceptable salt, ester, or prodrug thereof.
US10047103B2	Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
US10047100B2	Compounds from renewable resources Compounds of formula III: and salts thereof are disclosed. Also disclosed are methods for preparing compounds of formula III, intermediates useful for preparing compounds of formula III and methods for preparing compounds and materials from compounds of formula III.
US10047098B2	C5-C6-oxacyclic fused iminopyrimidinone compounds as bace inhibitors, compositions, and their use In its many embodiments, the present invention provides certain C5-C6-oxacyclic fused iminopyrimidinone compounds, including compounds Formula (I): or a tautomer thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein RN, R1, RA, ring A, m, n, -L1-, ring B, RB, and p are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed.
US10047097B2	Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.
US10047088B2	1H-1,8-naphthyridin-2-ones as anti proliferative compounds The present invention relates to novel antiproliferative 1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
US10047084B2	Imidazolone derivatives, pharmaceutical compositions and uses thereof This application relates to imidazolone compounds, pharmaceutically acceptable salts, solvents, polymorphs or prodrugs thereof, and further relates to pharmaceutical combinations comprising the foregoing substances and uses for preventing and treating protein kinase related diseases such as cancer, metabolic diseases, and cardiovascular diseases.
US10047078B2	Aminothiazole compounds Aminothiazole compounds of Formula (I) shown herein and pharmaceutical compositions containing one of such compounds.
US10047075B2	Pyridines and pyrimidines and use thereof The present disclosure provides pyridines and pyrimidines of Formula I and pharmaceutically acceptable salts and solvates thereof: wherein A, G, W1, W2, W3, and R5 are defined as set forth in the specification. The present disclosure also provides uses of the compounds of Formula I and pharmaceutically acceptable salts and solvates thereof. In certain embodiments, Compounds of the present disclosure are useful for treating pain. In another embodiment, Compounds of the present disclosure are useful for treating a disorder responsive to blockade of sodium channels, or alleviating symptoms of the disorder.
US10047069B2	Compositions comprising an inhibitor of lysine specific demethylase-1 Described herein are amorphous and crystalline forms of pharmaceutically acceptable salts of the lysine specific demethylase-1 inhibitor 4-[2-(4-aminopiperidin-1-yl)-5-(3-fluoro-4-methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-4-yl]-2-fluorobenzonitrile. Also described are pharmaceutical compositions suitable for administration to a mammal that include the lysine specific demethylase-1 inhibitor, and methods of using the lysine specific demethylase-1 inhibitor for treating diseases or conditions that are associated with lysine specific demethylase-1 activity.
US10047068B2	Optical resolution method of lenalidomide The problem addressed by the present invention is to provide a novel method for separating and purifying pure enantiomer of lenalidomide. Pure enantiomer of lenalidomide can be separated and purified by using, as the mobile phase, an organic solvent selected from the group consisting of aprotic solvents, secondary alcohols, and mixtures thereof.
US10047067B2	Composition for treating kidney disease comprising pyrazole derivative The present invention provides a composition for preventing or treating kidney disease, the composition comprising a pyrazole derivative compound or a pharmaceutically acceptable salt thereof; and the composition of the present invention is effective in reducing proteinuria, reducing cell formation between glomerular blood vessels and suppressing kidney fibrosis.
US10047066B2	IDO inhibitors Presently provided are methods for (a) modulating an activity of indoleamine 2,3-dioxygenase comprising contacting an indoleamine 2,3-dioxygenase with a modulation effective amount of a compound as described in one of the aspects described herein; (b) treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression in a subject in need thereof, comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; (c) treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; (d) enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent and a compound as described in one of the aspects described herein; (e) treating tumor-specific immunosuppression associated with cancer comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; and (f) treating immunosuppression associated with an infectious disease, e.g., HIV-I infection, comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount a compound as described in one of the aspects described herein.
US10047064B2	Flavagline derivatives The invention relates to compounds of the following general formula (I) in the form of one of the enantiomers thereof or a mixture of the enantiomers thereof, and the pharmaceutically acceptable salts and/or solvates thereof, especially for the use thereof as a medicament, more specifically in cancer treatment. The invention also relates to pharmaceutical compositions containing same and to the methods for the production thereof.
US10047062B2	Methods of chemical synthesis of Diaminophenothiazinium compounds including methylthioninium chloride (MTC) Methods of synthesizing and purifying certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as “diaminophenothiazinium compounds”) including Methythioninium Chloride (MTC) (also known as Methylene Blue) are provided.
US10047060B2	Process methods for phosphatidylinositol 3-kinase inhibitors A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
US10047058B2	Compounds and methods for inhibiting vacuolar ATPase A compound of Formula II, is provided. R1, R2 and R3 are independently either hydrogen, alkyl, aryl, halogen, alkoxy, nitro, amino or hydroxyl. X is either F, Cl, Br, I or CN. Y is either N or CH. Compositions that include Formula II can be used to inhibit vacuolar H+ ATPase.
US10047054B2	Method for the production of MDI dimer The invention relates to a method for the production of 4,4′-methylenebis(phenylisocyanate) dimer (MDI dimer) which is distinguished by an MDI dimer being obtained which is present in high purity. The MDI dimer which is produced according to the method according to the invention is distinguished by being essentially free of MDI and also urea derivatives. Furthermore, the invention relates to a corresponding MDI dimer and also the use thereof as crosslinker for polyurethanes.
US10047052B2	Bisaminoquinoline compounds, pharmaceutical compositions prepared therefrom and their use The present invention relates to novel bisaminoquinoline compounds, pharmaceutical compositions comprising these novel compounds and methods for inhibiting autophagy in biological systems. Methods of treating cancer in patients in need using compounds and/or compositions according to the present invention alone or in combination with at least one additional anticancer agent represent additional aspects of the invention. Methods of treating disease states and/or conditions in which inhibition of autophagy plays a favorable treatment role including rheumatoid arthritis, malaria, antiphospholipid antibody syndrome, lupus, chronic urticaria and Sjogren's disease, with compounds according to the present invention represent additional aspects of the invention.
US10047051B2	Substituted pyridines and method of use The invention discloses compounds of Formula I wherein X, R1, R2, and R3 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
US10047050B2	3,4-di-substituted pyridine compound, methods of using and compositions comprising the same 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is useful in the modulation of blood or serum uric acid levels. In some embodiments, 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is used in the treatment or prevention of disorders related to aberrant levels of uric acid. In some embodiments, 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is used for reducing serum uric acid levels in a human. Also described herein are compositions comprising 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid, and their use in the modulation of blood or serum uric acid levels.
US10047044B2	Amine Mining Collectors A family of amine mining collectors that uses alkoxylates allows for the easy adjustment of solubility and molecular weight useful because anionic and cationic mineral collectors require such varying degrees of solubility and molecular weight. The family of the present invention allows for the optimization of both parameters and an increase in collector efficiency.
US10047043B2	Thiol compound composition for optical material According to the present invention, it is possible to provide a polythiol composition, which comprises a polythiol (A) represented by formula (1) and a thiol compound (B) represented by formula (2). (In formula (1), p and q each independently represent an integer of 1 to 3.) (In formula (2), p and q each independently represent an integer of 1 to 3.)
US10047040B2	Sulfonylaminobenzamide compounds as anthelmintics The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates.
US10047038B2	Waste treatment process A waste treatment process and system is described, which finds application in dechlorinating carbohydrates and/or hydrolyzing dimethyl formamide and/or dimethyl formamide in a waste stream. The process includes treating the waste stream with base at a pH of from 11 to 14, and at a temperature of from 200 to 330° F.
US10047036B2	Method for the synthesis of hydroxy-triglycerides and uses thereof for the prevention and treatment of diseases The present invention relates to hydroxy-triglycerides, their synthesis, a pharmaceutical and/or nutraceutical composition which comprises at least one of said hydroxy-triglycerides, and a method which comprises the administration to a patient of a therapeutically effective quantity of at least one of said hydroxy-triglycerides or at least one of said pharmaceutical and/or nutraceutical compositions, for the prevention and/or treatment of at least one disease selected from cancer, metabolic/cardiovascular diseases, and/or neurological/inflammatory diseases.
US10047030B2	Coating to inhibit fouling of reactors for cumene hydroperoxide cleavage The disclosure concerns methods comprising forming a phenol and acetone mixture from decomposition of a cumene hydroperoxide or a phenol, acetone, and AMS from the decomposition of a mixture containing dicumyl peroxide in a system comprising one or more reactors where at least a portion of an inner surface of the one or more reactors has a polymer coating and wherein the coating inhibits build-up of a fouling precipitate on the coated inner surface of the one or more reactors as compared to such build-up in the absence of the coating.
US10047026B2	Process for reducing 1233xf concentration in 244bb The present disclosure provides a method for separating 244bb from 1233xf by using solid adsorbent selected from molecular sieves having an average pore size of 5 Å or greater.
US10047020B2	Reactors and systems for oxidative coupling of methane In an aspect, the present disclosure provides a method for the oxidative coupling of methane to generate hydrocarbon compounds containing at least two carbon atoms (C2+ compounds). The method can include mixing a first gas stream comprising methane with a second gas stream comprising oxygen to form a third gas stream comprising methane and oxygen and performing an oxidative coupling of methane (OCM) reaction using the third gas stream to produce a product stream comprising one or more C2+ compounds.
US10047015B2	High strength ceramic fibers and methods of fabrication A method and apparatus for forming a plurality of fibers from (e.g., CVD) precursors, including a reactor adapted to grow a plurality of individual fibers; and a plurality of independently controllable lasers, each laser of the plurality of lasers growing a respective fiber. A high performance fiber (HPF) structure, including a plurality of fibers arranged in the structure; a matrix disposed between the fibers; wherein a multilayer coating is provided along the surfaces of at least some of the fibers with an inner layer region having a sheet-like strength; and an outer layer region, having a particle-like strength, such that any cracks propagating toward the outer layer from the matrix propagate along the outer layer and back into the matrix, thereby preventing the cracks from approaching the fibers. A method of forming an interphase in a ceramic matrix composite material having a plurality of SiC fibers, which maximizes toughness by minimizing fiber to fiber bridging, including arranging a plurality of SiC fibers into a preform; selectively removing (e.g., etching) silicon out of the surface of the fibers resulting in a porous carbon layer on the fibers; and replacing the porous carbon layer with an interphase layer (e.g., Boron Nitride), which coats the fibers to thereby minimize fiber to fiber bridging in the preform.
US10047014B2	Plasma-sprayed tin coating having excellent hardness and toughness, the preparation method therefor, and a mold coated with said tin coating Disclosed is an agglomerated TiN powder, the powder comprising spherical aggregates having particle diameters of 40 to 80 μm and formed by the agglomeration of Ti and N having the atomic fractions of 72% and 28% respectively. Also provided is a TiN coating obtained using the powder. The three-strong-peak phase of the coating is a TiN phase, and also has partial TiO, TiO2, and Ti3O oxide phases; the coating has layered distribution of bright and dark phases, and the joint between the interior of the layered structure and the layer structure is provided with a small number of pores; the joint between the coating and a base has no microscopic defects such as cracks and is well jointed. The supersonic plasma-sprayed TiN coating achieves hardness as high as 1210HV0.1, thereby enhancing the wear resistance of the coating. The coating has good fracture toughness, thereby enhancing the fracture mechanical performance inside of the coating and extending the fatigue life of the coating. Also provided are a preparation method for the TiN coating, and a mold coated with said TiN coating.
US10047012B2	Oxide sintered compact and sputtering target formed from said oxide sintered compact An IGZO sintered compact composed of indium (In), gallium (Ga), zinc (Zn), oxygen (O) and unavoidable impurities, wherein an average length of cracks existing in the IGZO sintered compact is 3 μm or more and 15 μm or less. Provided is a sputtering target capable of suppressing the target cracks and reducing the generation of particles during deposition via DC sputtering, and forming favorable thin films.
US10047007B2	Formulation based on hydraulic cement added with amorphous glasses and micro-spheres for products of repair, maintenance or rehabilitation of concrete structures The present invention refers to a base formulation which serves to form a final product intended for the repair, maintenance or rehabilitation of concrete structures. Primarily, the base formulation contains cement in a percentage of 35% to 45% by weight of the final product. The base formulation also possesses amorphous glass in a proportion of 20% to 30% by weight of the final product, in ground from common glass, recycled glass or soda-lime glass. Finally, the base formulation may further possess solid quartz microspheres in a proportion of 10% to 20% by weight of the final product. This provides the final product with many desirable properties, such as high mechanical strength; high chemical resistance; easier application; easier ability to polish; prevents cold seals, leaving the final product thermally and dimensionally stable, among other desirable properties. The final products may include concrete correctors, waterproofing agents, coatings, among others.
US10047006B1	Hyaloclastite pozzolan, hyaloclastite based cement, hyaloclastite based concrete and method of making and using same The invention comprises a composition comprising hyaloclastite having a volume-based mean particle size of less than or equal to 40 μm. The invention also comprises a cementitious material comprising a hydraulic cement and hyaloclastite, wherein the hyaloclastite has a volume-based mean particle size of less than or equal to approximately 40 μm. The invention further comprises a cementitious-based material comprising aggregate, a cementitious material comprising a hydraulic cement and hyaloclastite, wherein the hyaloclastite has a volume-based mean particle size of less than or equal to approximately 40 μm and water sufficient to hydrate the cementitious material. A method of using the composition of the present invention is also disclosed.
US10046996B1	Multi-stage residential wastewater treatment tank and bactericide pump A multistage residential wastewater treatment system. The preferred system has three chambers. Wastewater flows into the first chamber via an inflow line. Primarily anaerobic treatment occurs in the first chamber. From the first chamber, wastewater flows into a second chamber. The second chamber is aerated, and primarily aerobic treatment occurs there. Substantially fully treated wastewater flows from the second chamber to the third chamber. The third chamber is substantially quiescent and anaerobic. Most remaining solids settle out in the third chamber. A bactericide pump is configured to introduce batch doses of bactericide in the desired volume to the third chamber at set intervals. After sufficient delay following introduction of the bactericide to allow for substantially complete toxicity to the bacteria in third chamber, effluent is pumped out of the tank by an effluent pump via an effluent line. The effluent pump preferably powers the bactericide pump.
US10046994B2	Method for treating liquids with gaseous ozone A method for treating contaminated liquids in a flow by ozone, wherein the ozone is fed in gas form into the flow at one point and then is mixed into the flow in stages by mixers following one another in the flow direction, so that an absolute quantity of introduced ozone increases after each mixer until a feed efficiency of more than 95 percent is reached.
US10046990B2	Electrolytic method of generating chloride dioxide with improved theoretical yield The invention is directed to an apparatus and methods of its use to generate chlorine dioxide. The apparatus comprises three cation exchange resin chambers in fluidic communication to convert chlorite salt into chlorine dioxide. Unlike previous converters, the invention utilizes an novel method of acidifying some of the chlorite to produce a more effective process. The invention can achieve a 100% theoretical yield which is s significant improvement over the 80% theoretical yield in previous attempts using non-acidifying chemistry. The method also avoids the need for expensive catalysts.
US10046989B2	Electrochemical system and method for on-site generation of oxidants at high current density An electrochemical system and method are disclosed for On Site Generation (OSG) of oxidants, such as free available chlorine, mixed oxidants and persulfate. Operation at high current density, using at least a diamond anode, provides for higher current efficiency, extended lifetime operation, and improved cost efficiency. High current density operation, in either a single pass or recycle mode, provides for rapid generation of oxidants, with high current efficiency, which potentially allows for more compact systems. Beneficially, operation in reverse polarity for a short cleaning cycle manages scaling, provides for improved efficiency and electrode lifetime and allows for use of impure feedstocks without requiring water softeners. Systems have application for generation of chlorine or other oxidants, including mixed oxidants providing high disinfection rate per unit of oxidant, e.g. for water treatment to remove microorganisms or for degradation of organics in industrial waste water.
US10046988B2	RO installation for flushing solutions The RO installation for producing ultrapure water, preferably for medicinal flushing solutions, with a raw water supply conduit, which leads to a feed tank, from which a conduit with a pump leads to the primary side of an RO membrane, from where a concentrate circulation conduit leads back to the feed tank, and with a permeate feed conduit and a first permeate circulation conduit, which either extends to a permeate return conduit, which leads to the feed tank, or communicates via a further permeate circulation conduit with the secondary side of the RO membrane, and with a filtrate outlet conduit is characterized in that the primary circuit including the feed tank, the conduit, the primary side of the RO membrane and the concentrate circulation conduit and the secondary circuit including the secondary side of the RO membrane, the first permeate circulation conduit and the further permeate circulation conduit may be flowed through by a disinfecting and cleaning agent independently of one another, wherein a disinfecting agent conduit connected to a disinfecting agent container communicates with the first permeate circulation conduit and the disinfecting agent conduit is provided with a disinfecting agent pump and that the permeate return conduit includes a pressure holding valve with a bypass valve.
US10046978B2	Method for processing packing material to recover aluminium The subject of the present invention is a method for processing metallized packaging materials, especially beverage cartons, or blister packaging.According to the invention, the aluminum is dissolved with the aid of acid and separated from the plastic. The metal-containing acid solution then undergoes pyrohydrolytic treatment and the acid is thus recovered. The aluminum can be recovered as valuable aluminum oxide.
US10046977B2	Process and plant for purifying red mud A process for purifying red mud including reduction of the red mud to reduced material, and traversing the reduced material with an oxygen-containing gas in the presence of a catalyst suitable for iron oxidation.
US10046976B1	Method of making inorganic gold compound A method of making the inorganic gold compound, such as tetrachloroauric acid, sodium tetrachloroaurate, potassium tetrachloroaurate, sodium tetracyanoaurate, and potassium tetracyanoaurate, includes the step of: treating gold with a halogen-containing oxidizing agent in a hydrochloric acid to obtain the inorganic gold compound, wherein the halogen-containing oxidizing agent excludes chlorine gas. The method of making the inorganic gold compound is simple, safe, time-effective, cost-effective, and environment-friendly, and has the advantage of high yield.
US10046974B2	Process for preparing a boron containing zeolitic material having MWW framework structure A process for preparing an aluminum-free boron containing zeolitic material comprising the framework structure MWW (BMWW), comprising (a) hydrothermally synthesizing the BMWW from a synthesis mixture containing water, a silicon source, a boron source, and an MWW template compound obtaining the BMWW in its mother liquor, the mother liquor having a pH above 9; (b) adjusting the pH of the mother liquor, obtained in (a) and containing the BMWW, to a value in the range of from 6 to 9; (c) separating the BMWW from the pH-adjusted mother liquor obtained in (b) by filtration in a filtration device.
US10046970B2	Process for purifying semiconducting single-walled carbon nanotubes A two-step sc-SWCNT enrichment process involves a first step based on selective dispersion and extraction of semi-conducting SWCNT using conjugated polymer followed by a second step based on an adsorptive process in which the product of the first step is exposed to an inorganic absorptive medium to selectively bind predominantly metallic SWCNTs such that what remains dispersed in solution is further enriched in semiconducting SWCNTs. The process is easily scalable for large-diameter semi-conducting single-walled carbon nanotube (sc-SWCNT) enrichment with average diameters in a range, for example, of about 0.6 to 2.2 nm. The first step produces an enriched sc-SWCNT dispersion with a moderated sc-purity (98%) at a high yield, or a high purity (99% and up) at a low yield. The second step can not only enhance the purity of the polymer enriched sc-SWCNTs with a moderate purity, but also further promote the highly purified sample to an ultra-pure level. Therefore, this two-step hybrid process provides sc-SWCNT materials with a super high purity, as well as both a high sc-purity (for example greater than 99%) and a high yield (up to about 20% or higher).
US10046969B2	Device for manufacturing and method for manufacturing oriented carbon nanotube aggregates An apparatus of the present invention for producing an aligned carbon nanotube includes: at least one injection section including at least one injection hole from which a raw material gas is injected to a base substrate; an exhaust vent for exhausting the raw material gas; and an exhaust section including a plurality of exhaust vents, the plurality of exhaust vents being provided so as to be closer to the exhaust vent than a plurality of injection holes included in the at least one injection hole of the at least one injection section.
US10046967B2	Process for sulphur recovery with concurrent hydrogen production from NH3 containing feed Disclosed is a method for the production of hydrogen from a H2S-containing gas stream also containing ammonia, comprising subjecting both gas stream to catalytic oxidative cracking of both the H2S and the NH3, so as to form H2, S2 and N2. In this method, preferably, an additional amount of oxygen is added as compared to the amount used for H2S catalytic oxidative cracking. Also, preferably, the contact time of the gas stream with the catalyst is increased. The catalyst preferably is provided as a single bed, and then preferably comprises iron and molybdenum supported by a carrier comprising aluminum. The preferred carrier is alumina. The iron and molybdenum preferably are in the form of sulfides.
US10046960B1	Refrigerator and dispenser A refrigerator having a dispenser that includes an outlet and that is configured to dispense content through the outlet and along an output flow path. The refrigerator also includes a detection unit configured to detect user activity that is indicative of a desire to fill a container with content using the dispenser. The refrigerator further includes an optical system that is configured to, in response to detecting the user activity, direct a beam of light along at least a portion of the output flow path of the dispenser to assist a user in positioning a container to receive content dispensed along the output flow path.
US10046954B1	Suspension type lifting device with steering mechanism A suspension type lifting device includes a base unit, a balance unit, two servo units, a hanging unit and a steering unit. The steering unit is mounted in the base unit and includes a housing having a receiving chamber, a control module mounted on the housing, and at least one gyroscope rotatably mounted in the receiving chamber of the housing and electrically connected with the control module. When the at least one gyroscope performs the self-rotation and the side-rotation simultaneously, the side-rotation produces a torque to change a direction of the self-rotation and to produce a precession, so as to change the direction of the lifting device.
US10046949B2	Elevator installation deflecting unit A deflection unit for guiding and deflecting the support apparatus of an elevator system includes a deflection roller and an axle which is mounted on a carrier and on which the deflection roller is mounted and is freely rotatable. The axle has an axle head that axially secures the axle on one end. For torsion-free mounting of the axle, a securing member is bolted onto the carrier and supported on an anti-rotation safeguard section arranged on the axle head. A horseshoe-shaped retaining part as a retaining means for axially securing the axle on the carrier is mounted on the axle on the end opposite from the axle head. An annular securing member, which is connected by bolts to the retaining part, is used for securing the retaining part.
US10046948B2	Variable elevator assignment A system 110 includes an input/output 113 unit for receiving a user request to call an elevator 101, 102 and a processor 111 for processing the user request to assign an elevator to the user 105. The processor performs one of a first assignment process and a second assignment process. The first assignment process includes determining whether a delay condition exists for delaying assignment of the elevator to the user 202, delaying assignment of the elevator to the user based on determining that the delay condition exists 203, and assigning the elevator to the user based on determining that the delay condition does not exist 204. The second assignment process includes assigning the elevator to the user and notifying the user of the assignment, determining whether an assignment change condition exists 206, changing the assignment to another elevator based on determining that the assignment change condition exists 207, and notifying the user of the assignment change 208.
US10046946B2	Measuring weight of a compartment Disclosed a load measurement system (100) includes a compartment (110), a damper (112) and a weight calculation unit (131). The damper (112) is configured to be positioned between the compartment (110) and a platform (121) and to compress at a predetermined rate based on a load of the compartment (110). The weight calculation unit (131) is configured to calculate a weight of the compartment (110) based on the compression of the damper (112).
US10046941B2	Cable support stand A cable support system includes a frame, an axle disposed within the frame, and a drum or roller having a rim for receiving the axle such that the drum is supported by and rotates on the axle, wherein the drum is in rollable contact with the cable for supporting the cable and configured for cable to move across surface of the roller while the roller is rotating to facilitate paying out or taking up the cable as the roller rotates. A stand includes a top portion in contact or physical communication with the frame and a plurality of legs which extend downwardly from the top portion, elevating the frame to facilitate the pay out or taking up of the cable over objects below the frame. The system is capable of switching between at least two different states or modes of use: a first mode, in which the roller and frame are positioned above the top portion; and a second mode, in which the roller and frame are positioned below the top portion of the stand, generally hanging from or suspended from the top portion of the stand.
US10046936B2	Stacker device to stack sheets of print media Stacker device to stack sheets of print media. The stacker device comprises a tray to stack the sheets. The tray comprises an M-shaped tray section to apply an M-shaped profile to a sheet along a direction perpendicular to the sheet's advance direction to reduce curling. The stacker device further comprises a roof. The roof comprises at least one adjustable roof portion to limit a height of a curl of the sheet.
US10046935B2	Multi-banknote cassette with movable stopper and banknote stacking method thereof Provided is a multi-banknote cassette with a movable stopper, which is capable of storing various kinds of banknotes at the same time. The multi-banknote cassette includes a movable stopper which is installed in a stack guide for guiding banknotes introduced into a cassette body of the banknote cassette toward a banknote stopper, and rotated to protrude from or retreat into a transfer path of the banknotes. When a banknote having a relatively small size among the banknotes inserted into the banknote cassette is introduced, the movable stopper is rotated to protrude from the stack guide and regulates the front end of the introduced banknote, and when a banknote having a relatively large size is introduced, the movable stopper is rotated to retreat into the stack guide, and a banknote stopper installed at the rear of the stack guide regulates the front end of the introduced bank.
US10046928B2	Transport apparatus A transport apparatus includes an accommodating unit that accommodates a recording medium and that is mounted to be capable of reciprocating with respect to a body portion, a loading plate that is provided in the accommodating unit to be movable up and down and that is loaded with the recording medium, a lifting unit that moves up the loading plate to a position where the recording medium is able to be fed by winding wires connected to opposite end portions of the loading plate to suspend the loading plate, and moves down the loading plate by feeding the wires, and a receiving member that is provided on a bottom surface of the accommodating unit and that receives abutments provided on the loading plate when the loading plate moves down.
US10046925B2	Blowing device for a rotary airlock Disclosed is a blowing device for a rotary air lock, comprising a flushing gas stream that is fed by a gas supply line (12) in order for adhering material to be flushed and blown out of at least one compartment (20-24) of the rotary air lock (20-24) when said compartment is located next to a product outlet of the rotary air lock. A blowing unit (30), which comprises at least one blowing tube (32) and is located in a feeding shoe (10) that is arranged at the product outlet, directs the flushing gas stream to at least one compartment (20-24) of the rotary air lock.
US10046924B2	Core conveying device and core conveying method A core conveying device includes a plurality of holding devices, a support section, a moving device, and a mounting table. The support section has a hole formed at a position corresponding to a positioning pin and is connected so as to slide in a horizontal direction with respect to the moving device. A size of a lower end opening of the hole is larger than a size of an upper end of the positioning pin. The support section is configured such that, when the support section is moved downward so as to grip the core, as the positioning pin abuts against an inner surface of the hole and the support section slides in the horizontal direction with respect to the moving device, a position of the support section in the horizontal direction with respect to the core is determined.
US10046921B2	Apparatus for grouping piece goods and method for format change The invention relates to a handling apparatus (1) for piece goods (2) that comprises at least one divider finger (14, 46, 51), which is introducible to a transport plane (5), largely perpendicular, from below, with the at least one divider finger being connected to a divider bar element (13, 13*, 43, 50). The divider bar element is movably arranged below the transport plane (5) and is guided in a specified movement path. The divider bar element is detachably connected to a profile element (11, 41). During a format change, the divider bar element is toolessly detached and interchanged for another divider bar element, which has divider fingers that are positioned differently and/or spaced apart differently from the divider fingers of the removed divider bar element.
US10046919B1	Apparatus and method for separating food product from conveyor belt A food production apparatus includes a conveyor belt and a wire scraper. The conveyor belt supports and transports a food product. The wire scraper includes a wire and a motor. The wire is located above and extends across the conveyor belt to temporarily separate the food product from the conveyor belt. Operation of the motor causes the wire to continuously cycle back and forth between 1) movement in a first direction above and across the conveyor belt and 2) movement in a second opposite direction above and across the conveyor belt.
US10046907B2	Underwater storage tank and fill control mechanism A liquid storage tank comprising an outer container wherein the outer container is rigid and has at least one inner container disposed within the outer container. The at least one inner container contains at least one stored liquid which may be refilled from a surface vessel or host facility. The at least one inner container is flexible and pressure balanced while the volume of the outer container remains fixed, and the volume of the at least one inner containers is variable. Disposed on the outer container is a balance assembly containing an isolation valve, a check valve, and a flexible bladder. The balance assembly allows for the hydrostatic pressure to be maintained during chemical dosing and tank raising operations.
US10046905B2	Intermodal container tank structure A water treatment tank is constructed from several adjoining intermodal containers (ICs). The adjoining ICs are angularly disposed relative to each other so as to surround a tank area. Each IC has a reinforced sidewall defining a tank wall or tank wall part. A bracing structure is attached to ICs end walls at each junction between adjoining ICs. The tank having a liner supported at the sidewalls and covering the ground at the tank area.
US10046901B1	Thermally insulating packaging A thermally insulating packaging to hold an item includes a solid compostable or recyclable shell that is formed primarily of a plant fiber, and a bottom cover. The shell includes a floor, a plurality of inner side walls that are coupled to the floor, a rim coupled to the plurality of inner side walls, and a plurality of outer side walls that are couple to the rim. The floor and the plurality of inner side walls define an interior space of the shell to receive the item and an opening to the interior space. The plurality of inner side walls and plurality of outer side walls have a space therebetween that defines a gap. The gap can be an air-filled cavity, or be filled with a compostable or recyclable core material.
US10046900B2	Insulating container and latching mechanism According to an aspect of the invention, a latching mechanism/device is provided, as well as a method of maintaining a closed position between opposing first and second portions of a container. The latching mechanism includes a latch attached to the first portion and a latch keeper integrally molded to the second portion. The latch keeper includes an elongated keeper slot and a recessed pocket formed in the keeper slot, such that when at least a portion of the latch is received within the recessed pocket, the container is closed and/or sealed.
US10046899B2	Methods for disinfecting or sterilizing articles Disclosed herein are materials and methods for reducing, preventing, or eliminating the biological contamination of surfaces in spaces that are reasonably partitioned, defined or contained. A reagent that includes peroxides or molecules that includes peroxide bonds are contacted with at least one surface of an article. Some of these methods include disinfection within an apparatus and may include the step of volatilizing the peroxide bond containing agent, through, for example, vapor pressure and vaporization or evaporation effects, the addition of volatilization aids, or passive or assisted diffusion at modest temperatures and relatively long exposure times measured in some embodiments on the order of hours, days, or months. In some embodiments a liquid that includes a peroxide moiety is added (for example, during manufacture or subsequently) to a package, container, or any other reasonably partitioned or contained volume and allowed to migrate within the confined space for a period of time sufficient to disinfect the inner surfaces of the container and articles it contains.
US10046898B2	Packaging material A packaging material is formed from a shock-absorbing plate material and stored in a packaging box with a packaged article. The packaging material includes a base portion and a shock absorbing portion. The shock absorbing portion surrounds three sides of a space along a main surface of the base portion. First and second vertical plate portions of the shock absorbing portion face each other and continue to the base portion. In the shock absorbing portion, a third vertical plate portion continues to the second vertical plate portion, and a fourth vertical plate portion continues to the third vertical plate portion. The fourth vertical plate portion is overlaped on the first vertical plate portion. A hook portion of the shock absorbing portion continues to the fourth vertical plate portion, and has a second cut in which a bottom portion of the first cut of the first vertical plate portion is inserted.
US10046893B2	Pattenred film for forming fluid-filled blister, microfluidic blister, and kit and method of forming A patterned thermoplastic elastomer (TPE) film for fabricating a liquid-filled blister, has a blister-sized cavity in fluid communication with a microfluidic channel via a gating region. The gating region is defined by a relief pattern that has at least one of the following: at least 5 separate compartments defined by respective recesses in the first side, each of the recesses bounded by walls that separate the compartments from each other, the recess, or the channel; at least 5 walls defined by the patterning of the first side, the walls separating a plurality of compartments from each other, the recess, or the channel, wherein the walls have a mean thickness that is less than a mean height, and each pair of walls has a mean separation greater than twice the mean thickness; an array of separate compartments bounded by walls defined by the patterning of the first side that collectively define a polygonal regular planar tiling with at least 50% of the surface area of the gating region being open spaces; and a focusing region in fluid communication with the cavity, and a seal region having at least one wall defined by patterning of the film, wherein the at least one wall separates the focusing region from the seal region, and a shape of the at least one wall tapers the focusing region towards the seal region.
US10046892B2	Tamper-evident device and valve using same A tamper-evident device for valves comprises: an anti-theft buckle (1), provided with an anti-theft buckle body (17), a pulling portion (4), a tearable portion (5), an elastic hook (7), and a position limiting surface (6); an anti-theft cover (2), provided with a position limiting contour (8) and a hook receiving portion (9); and a position limiting slot (10) provided at a passage outlet (13) of a valve body (3). During use, the anti-theft cover (2) is connected to the passage outlet (13), and the elastic hook (7) is hooked to the hook receiving portion (9) and fitted to position limiting slot (10) to limit relative positions of the anti-theft cover (2) and the valve body (3). Also disclosed is a valve having the temper-evident device. The temper-evident device is easy to open and can effectively prevent stored materials from being stolen.
US10046889B2	Container with molded bag on valve assembly The present disclosure provides a container and a process for producing the container. In an embodiment, the process includes placing a sleeve bag on valve assembly (SBoV) in a blow mold apparatus. The blow mold apparatus has two opposing and movable molds. The SBoV has a valve seat. The process includes extending a parison of flowable polymeric material around the SBoV and between the opposing molds. The process includes moving the opposing molds to a closed position and pressing an upstream portion of the parison against the valve seat. The process includes blow molding a downstream portion of the parison into a container-shape within the closed mold. The process includes forming a container with the valve seat melt bonded to a neck portion of the container.
US10046886B2	Container and lid hanging structure thereof A lid hanging structure of a container is disclosed in the present invention. The container includes a base, side plates and a lid. the hanging structure includes hanging members and hanging slots, wherein the hanging members are engaged or disengaged with the hanging slots respectively so as to hang the lid on the container or remove the lid from the container, and one of the anging members and the hanging slot is provided on the lid and the other is provided on the side plates. According to the lid hanging structure, it is convenient to remove the lid from the container when necessary. That is to say that, the lid can be removed directly when not in use or in the hanging state, and can be removed by simple operation in the hanging state, so as to reduce the amount of labor, and the structure is simple and the cost is low.
US10046884B1	Returnable shipping cartridge and rack A material-supporting cartridge comprises a frame having an upper surface with an opening, and a pin removably positioned in the opening in a first orientation with a first end of the pin positioned in the frame and a second end of the pin positioned a first height above the upper surface. The pin is dimensioned to be removed and inserted into the opening in a second orientation with the second end of the pin positioned in the frame and the first end of the pin positioned a second height above the upper surface, the first height being greater than the second height. The frame further includes a support tube dimensioned to receive the pin in each of the first and second orientations. The material-supporting cartridge can be used with a rack that defines multiple stacked rows having a vertical spacing between adjacent rows, the vertical spacing being greater than the second height.
US10046881B2	Resin container and bag-in-box A resin container of the invention is the resin container capable of storing a predetermined amount of fluid having flexibility, the resin container including a first surface part formed with an inlet/outlet part for the fluid, a second surface part connected to the first surface part and forming a peripheral surface, and a third surface part arranged at an opposite side of the first surface part and connected to the second surface part, wherein the first surface part is formed with a first recess recessed from the first surface part toward a third surface part side, and the second surface part is formed with a second recess recessed toward the center of the container from the first surface part to the third surface part.
US10046876B2	Method for transferring items to be packaged into containers and for transporting the filled containers onward In the method for transferring at least one item to be packaged into a container and for transporting the filled container onward the at least one item to be packaged is conveyed in a conveying direction to a transfer position by a linear motor transport device. The at least one item to be packaged is then moved from the transfer position to an intermediate storage area, which is arranged next to the transport device. A container is conveyed in the conveying direction to the transfer position by the linear motor transport device, and the at least one item to be packaged is moved back from the intermediate storage area to the transport device, thus filling the container. Afterwards, the filled container is moved onward in the conveying direction by the linear motor transport device.
US10046874B2	Sealing system and method for gusseted and zippered bags An ultrasonic sealing tool including an anvil with a sealing surface, a horn with a sealing surface facing the sealing surface of the anvil, the sealing surface of the anvil including a plurality of beads including a first bead having a first height and at least one second bead having a second height, the second height being less than the first height, the ultrasonic sealing tool delivering ultrasonic vibrations via at least one of the anvil and the horn to create a closure seal in a work piece positioned between the anvil and the horn, the closure seal including a first seal created by the first bead and at least one second seal created by the at least one second bead, the first seal having a weld depth greater than a weld depth of the at least one second seal.
US10046873B2	Device for filling and closing bags for containing paper documents, such as banknotes and the like A device for filling and closing disposable bags for containing banknotes comprises an upper container for temporarily housing banknotes, provided with a bottom with an opening for the exit of the banknotes from the container, a piston for pushing the banknotes towards the opening on the bottom of the container, a bag made of flexible plastic film, intended to be filled with the banknotes temporarily housed in the container, a support for the bag containing the banknotes, vertically movable through controlled lowering means and placed below the container, sealing bars arranged between the upper container and the movable support, and an electromagnetic stop element that can be controlled to lock the movable support with respect to the sealing bars, said electromagnetic stop element consisting of an electromagnet applied to the movable support and of a fixed element made of ferromagnetic material, adapted to face the electromagnet in operative condition.
US10046872B2	Viscous-material filling method A method for transferring a viscous material from a container into a dispensing syringe having first and second ends, the second end being a discharge port smaller than the inner diameter of the main body portion, includes inserting into the syringe a plug configured to permit gas flow in only one direction to divide a chamber within the syringe into a first sub-chamber in communication with the discharge port and a second sub-chamber in communication with the first open end of the syringe. Then, a rod is inserted into the syringe from the first open end of the syringe to engage the plug, and the viscous material is extruded from the container and through the discharge port into the first sub-chamber of the syringe. While the first sub-chamber is being filled with the viscous material, the plug and the rod are moving away from the discharge port.
US10046871B2	Electronic cigarette and fluid dispensing system An electronic cigarette and fluid dispensing system (E-Cig FDS) that utilizes an electronic cigarette (e-cig) having an inner end, an outer end, and an outer surface with a first aperture and a second aperture, and a keyed fluid dispenser having a body with an inner surface, an outer surface, an open first end, and a second end. Located within the body at the first end is a plunger that can slideably move inside the body. Extending from the body's second end is an injector dimensioned to interface with the first aperture or second aperture. The fluid facilitates the smoking, or vaping, of the e-cig. A user can selectively choose if the fluid is safe, non-nicotine or nicotine-infused. The E-Cig FDS provides visual differentiation of the type of fluid that is being smoked, or vaped.
US10046870B2	Flexible bag A flexible bag and a method for filling a flexible bag which is collapsed when empty, wherein at least one fastening means is provided on a surface of the flexible bag such that at least two upper parts of the flexible bag can be held together by this at least one fastening means during a first part of filling of the flexible bag, whereby the fastening means is designed to release when the bag is filled to a certain amount such that the two upper parts being held together by the fastening means will lose contact.
US10046862B2	Electronic display mounting apparatus A mounting apparatus includes a cradle, a stand, a cradle attachment member, and a rotation member. The cradle includes an electronic display attachment member which is configured to removably attach an electronic display to the cradle. The cradle attachment member is configured to removably attach the cradle to the stand. The rotation member is configured to allow rotation of the electronic display when it is attached to the electronic display attachment member.
US10046860B2	Windshield device, aircraft, and power control method for windshield heater The present invention provides a windshield device including: a windshield; a heater that is provided in the windshield and configured to generate heat by energization; a temperature sensor that is provided in the windshield and configured to detect a temperature; and a control unit that performs power control on the heater. The control unit is configured to supply an input power to the heater, the input power being acquired by applying a detected temperature detected by the temperature sensor to a function that is determined in accordance with a dew-point temperature of an inside of a compartment separated from an outside of the compartment by the windshield.
US10046858B2	Delivery of payloads using aircraft Aspects of the disclosure include a method, system, and computer program for delivering a product. The method includes determining a delivery location and time for a payload using an aircraft. A recipient is notified of the delivery location and time. A first signal is received from the recipient. The time or location of the delivery location and time is changed, dynamically, based on the first signal. The payload is delivered to the recipient.
US10046856B2	System and method for controlling takeoff and landing of drone Disclosed herein is a system and method for controlling the takeoff and landing of a drone. The system for controlling the takeoff and landing of a drone includes: a landing control device configured to vary the transmission range of Low Frequency (LF) landing control signals based on whether a response signal to a transmitted landing control signal in the transmission range is received, and to transmit a landing signal if the varied transmission range is less than a minimum radius; and a drone configured to fly in a control signal-based flight mode based on a landing control signal when receiving the landing control signal transmitted from the landing control device during GPS signal-based flight, and to land at a destination by flying in a landing mode when receiving a landing signal from the landing control device during flight in the control signal-based flight mode.
US10046852B2	Hub-mounted active vibration control (HAVC) devices, systems, and methods Hub-mounted active vibration control (HAVC) devices, systems, and related methods are provided. An HAVC device (100) includes a housing (206) having a tolerance ring (600) attached to a rotary hub (702). The tolerance ring can accommodate dissimilar coefficients of thermal expansion between dissimilar metals. The HAVC device can also include a plurality of coaxial ring motors (308A, 308B, 310A, 310B) configured to rotate a plurality of imbalance masses for controlling vibration. An HAVC system can further include a de-icing distributor (208) for communicating instructions to one or more heating sources (HS) provided at one or more rotary blades (802) of a vehicle or aircraft. A method of controlling vibratory loads occurring at a moving platform can include providing a moving platform, mounting a vibration control device to a portion of the moving platform, and rotating at least one pair of imbalance masses such that the combined forces of the masses substantially cancel unwanted vibration of the platform.
US10046850B2	Aircraft wing shift device An aerial vehicle includes a fuselage, a wing, and a wing shift device. The wing shift device is configured to be coupled to the fuselage. The wing shift device comprises a plurality of apertures for coupling the wing to the aerial vehicle. The plurality of apertures are configured to permit the wing to be shifted in a forward or aft direction along the fuselage based on a center of gravity of the aerial vehicle.
US10046849B2	Fuel tank, main wings, aircraft fuselage, aircraft, and moving body The purpose of the present invention is to provide a fuel tank, main wings, an aircraft fuselage, an aircraft, and a moving body, which enable working hours and costs involved in a manufacturing process to be reduced, and weight increases to be prevented. The fuel tank includes a structural member in which carbon fiber reinforced plastic (CFRP) is used, the carbon fiber reinforced plastic (CFRP) including a reinforcing material that includes carbon fibers and a matrix that includes plastic. The structural member is formed by laminating a conductive sheet between prepregs of the carbon fiber reinforced plastic (CFRP). In this case, a cut surface of the structural member formed by cutting the structural member may be exposed on the inside in which fuel is stored.
US10046843B2	Interior module installation in an aircraft fuselage A method of installing interior modules to support structures in an aircraft fuselage comprises attaching fixed ends of a plurality of tie rods to the support structures; and determining installation length of the tie rods, installation spacing between free ends of the tie rods, and installation orientation of the tie rods prior to positioning the interior module for installation. The method further comprises securing tie rod holding fixtures to the tie rods to hold the spacing and orientation at or near final configuration to facilitate installation of the interior modules.
US10046839B2	Reinforced surf leash A surfboard leash apparatus is disclosed. The surf leash apparatus includes a cuff for attaching to a limb of a surfer, the cuff having an inner surface, the inner surface of the cuff having a pattern of compressible grips disposed thereon. The surf leash further includes an attachment mechanism for attaching to a surfboard, and a leash cord connected between the cuff and the attachment mechanism. The leash cord includes an elastic fiber rope core having a predetermined amount of stretch, and an extruded thermoplastic urethane cord surrounding the elastic fiber rope core. The extruded thermoplastic urethane cord has an elasticity corresponding to the predetermined amount of stretch of the elastic fiber rope.
US10046838B1	Supski paddle system A paddle board has two tracks integrally associated therewith for the further attachment of a slide within each track thereon. Thus, to effect motion of the slide associated with the track the Supski Paddle System has two actuation drives that are rotationally associated with the aforementioned slides one to each slide respectively. Upon user actuation of the drive using a pole associated with the drive the slide is directed to move longitudinally upon a track or to insert a paddle into and out of the water.
US10046837B2	Watercraft with retractable fin In one example, a watercraft includes a buoyant body in the form of a single piece structure sized and configured to support the weight of one or more users. The watercraft also includes a retractable fin connected to a pin that resides in a fixed location relative to the body, the pin including a side surface that is in contact with the body. The retractable fin is rotatable about the pin between an extended position and a retracted position, and the retractable fin includes an engagement portion that is engageable with a first portion of the body and with a second portion of the body. The retractable fin assumes the extended position when the engagement portion is releasably retained by the first portion of the body, and the retractable fin assumes the retracted position when the engagement portion is releasably retained by the second portion of the body.
US10046836B2	Retractable fin and fin box A retractable fin system having a retractable fin and fin box is disclosed. An example retractable fin system includes a housing insertable into an opening in a watercraft board. The example retractable fin system also includes a retractable fin. The example retractable fin system also includes a bias to maintain the retractable fin in a default outward position from the housing. The bias retracts the retractable fin into the housing on contact with an outside force.
US10046830B2	Straddle-type vehicle A snowmobile includes a transmission unit that transmits a driving force generated by an engine to the ground surface, in which ground touching portions of the transmission unit that are spaced apart from each other in the vehicle width direction receive reaction forces mutually different in magnitude from the ground surface; a suspension that supports the transmission unit so as to swing in the up-down direction; and a vehicle body vibration control damper extending between a first portion and a second portion that are spaced apart from each other of the vehicle body frame and a member fixed to the vehicle body frame, the vehicle body vibration control damper generating a damping force against variations that change the distance between the first portion and the second portion.
US10046827B2	Reaction force adjustment support device, method thereof and non-transitory computer readable medium A reaction force adjustment support device includes: a pressure data storage unit storing pressure data of respective spring chambers; a graphic user interface unit displaying a display screen; a reaction force calculator calculating reaction force data by using the pressure data of the respective spring chambers stored in the pressure data storage unit; a graph generating unit generating a graph of reaction force characteristics by using the reaction force data calculated by the reaction force calculator; and a controller displaying a screen for adjusting a reaction force where the screen has an operation portion for adjusting spring pressures provided for the respective spring chambers and a drawing area of the graph on the display screen, and controlling the reaction force calculator and the graph generating unit by user's operation with respect to the operation portion with the pressure data changed for the respective spring chambers to vary the graph.
US10046824B2	Electric vehicle The present invention refers to an electric vehicle. As compared with the solution in prior art which is that assembling the finished product of wheel hub motor with the casing, the inventor of present invention creatively dismantles the structure of the original finished product of wheel hub motor with discarding at least one hub cover. Such solution simplifies the structures and reduces the weights of the wheel hub motor and the electric vehicle, moreover, it can reduce the gap between the casing and the wheel hub motor and thus decrease the overall thickness of the electric vehicle, especially decrease the thickness of the electric unicycle for easy to carry.
US10046821B2	Saddle type vehicle A saddle type vehicle wherein the supporting rigidity of a rear fender frame is enhanced while securing a degree of freedom of a shape of a vehicle body frame main body. A shock absorber bracket wherein an upper end portion of a rear shock absorber for supporting a rear wheel thereon is coupled and attached to a vehicle body frame main body. A rear fender frame includes a plurality of supported portions in a front region thereof. At least part of the plurality of supported portions is co-fastened to the shock absorber bracket together with the upper end portion of the rear shock absorber, and the remaining supported portions are fixed to the vehicle body frame main body.
US10046818B1	Rubber track wheel path reinforcement An endless rubber track belt includes an endless, elongate carcass having an outer surface, an inner surface, and at least one reinforcing layer. The inner surface defines a plurality of wheel path areas. A plurality of tread lugs are disposed on the outer surface. A plurality of guide lugs are disposed on the inner surface, where each guide lug includes oppositely disposed drive faces, an upper face between said drive faces, and oppositely disposed end faces. At least one reinforcement strip is disposed inward from the inner surface and outward from the at least one reinforcement layer. The at least one reinforcement strip is positioned adjacent the plurality of wheel path areas. The at least one reinforcement strip may include a bias ply formed of two layers of cords arranged in opposite +/− bias angles. The +/− bias angles may range from about +/−20° to about +/−80°.
US10046817B2	Scallop resistant idler heat treatment An idler wheel for use with a track chain of a vehicle that includes a plurality of track pins and bushings comprises a main body that includes a generally cylindrical configuration defining an axis of rotation, a circumferential direction and a radial direction, the main body including a central portion disposed along the axis of rotation defining an axial extremity of the radial portion, and at least a first outside portion disposed along the axis of rotation that includes alternating regions adjacent each other circumferentially having a different hardness relative to each other.
US10046812B2	Industrial truck An industrial truck is proposed comprising: a lifting frame; an operator compartment which can be moved upwards and downwards; a lateral push frame, arranged on the operator compartment, in the front thereof, and which can be moved upwards and downwards together with the operator compartment and carries a load-receiving device, which can be moved back and forth; and a vibration-damping means, which can be moved upwards and downwards, for damping vibrations. The vibration-damping means being arranged between the operator compartment and the load-receiving device, is designed to make vibration compensation movements of the load-receiving device relative to the operator compartment possible. Preferably, an over-reach device is provided, combined with the vibration-damping means, for moving the lateral push frame to the straight forward travel direction of the industrial truck and relative to the operator compartment, so as to increase the lateral movement range of the load-receiving device relative to the operator compartment.
US10046809B2	Body component for a motor vehicle A plate-shaped body component for a motor vehicle has a planar core zone, a planar edge zone and a first intermediate zone, which is set off from the core zone and from the edge zone by at least one step each. The core zone and the edge zone are deflected against the first intermediate zone in opposite directions of a surface normal of the first intermediate zones.
US10046808B2	Device for attaching a cross-member of a driver's compartment of a motor vehicle The invention relates to a device for attaching an end of a cross-member of a driver's compartment of a motor vehicle to the assembled shell, which includes an attachment element provided with a first surface, for receiving the cross-member of a driver's compartment, and with a second surface opposite the first surface. Said device comprises first and second reinforcements extending from the second surface and each including: a base connected to the attachment element and to be attached to a portion of the vehicle, two side walls extending from the base and connected to the attachment element.
US10046806B2	Vehicle body structure for automobile A vehicle body structure for an automobile includes a damper base connected to an outer wall of a rear side frame in a vehicle width direction on a rear side of a cross member and including a first bead projecting inward in the vehicle width direction and extending in an up-down direction and a damper support portion projecting outward in the vehicle width direction disposed on both sides of the first bead in a front-rear direction, a rear wheel house having a second bead extending in the up-down direction to overlap with an inner surface of of the first bead in the vehicle width direction, and a gusset having a third bead extending in the up-down direction to overlap with the inner surface of the first bead in the vehicle width direction and connected to an upper wall of the rear side frame.
US10046800B2	Trailer wheel targetless trailer angle detection A backup assist system for a vehicle and trailer combination includes a steering system, a camera generating an image of the trailer, and a controller. The controller receives the image and identifying a wheel therein, determines a value in a kinematic model of the vehicle and trailer combination using at least one of an aspect ratio or location of the wheel in the image, and uses the value in the kinematic model to control the steering system.
US10046799B2	Walk behind power equipment with zero turn capability A drive assembly (140) for a walk-behind, powered device operably couples an engine (110) of the powered device to a mobility assembly (120) to provide mobility of the powered device responsive at least in part to operation of the engine (110). The drive assembly (140) includes a transmission shaft and a mechanical power reversing assembly (150). The transmission shaft selectively receives first drive power or second drive power coupled from the engine (110) to drive a first drivable component (122) and a second drivable component (124) of the mobility assembly (120). The first and second drivable components (122, 124) are disposed substantially at opposing sides of the powered device. The mechanical power reversing assembly (150) is selectively engagable to convert the first drive power generated for the first drivable component (122) into the second drive power provided to the second drivable component (124) and vice versa.
US10046797B2	Vehicle control systems and methods Systems for controlling the speed and direction of vehicles such as tractors, including vehicles that have low to zero turning radius capability. Systems include steering and speed coordination systems that control the direction and speed of rotation of vehicle drive units.
US10046793B2	Methods and systems for automated driving Methods and systems for controlling a driving feature for an automated driving system are provided. In one embodiment, a method includes: receiving a first sensor signal from a first sensor; receiving a second sensor signal from a second sensor; selectively determining a driver intent based on at least one of the first sensor signal and the second sensor signal; and controlling the driving feature based on the driver intent.
US10046792B2	Limp aside steering assist with estimated motor current The present invention relates to an electromechanical motor vehicle power steering mechanism for assisting steering of a motor vehicle by conferring torque generated by an electric motor to a steering mechanism. A steering controller receives at least signals representative of the vehicle velocity and the torque applied to a steering wheel and a rotor position signal to determine a target motor torque, a motor controller which receives the target motor torque from the steering controller and transfers it into target voltages expressed in a coordinate system fixed to the stator and a motor driver which transforms the target voltages into motor currents, at least one current measurement unit which measures the motor currents, wherein the mechanism further comprises a current estimation unit which estimates the target currents and a diagnostic unit which compares the estimated target currents to the measured motor currents in order to identify and remedy occurring faults.
US10046791B2	Moisture sensor and steering system A recessed portion is formed in an inner wall surface of a lower portion of a reduction gear housing (a lower wall in FIG. 2) in the direction of gravity and between a bearing 44 and an outer wall of the reduction gear housing (a right side wall in FIG. 2). The recessed portion is formed to have such a depth that the recessed portion does not penetrate the reduction gear housing. The recessed portion is formed in the reduction gear housing within a given range in a circumferential direction with respect to the axis of a rack shaft serving as the center. A moisture sensor is mounted in the recessed portion to detect water infiltrating into a housing. The moisture sensor has a transmission circuit that operates using a water battery as a power supply source. The water battery generates power when water flows into the water battery.
US10046785B2	Methods and apparatus for child transport cover Methods and apparatus for a child transport cover according to various aspects of the present invention may operate in conjunction with a child transport, such as a stroller, and a flexible outer cover coupled to a structural system. The structural system may comprise a main frame disposed on an interior portion of a cover. The main frame may comprise a rigid support portion and a flexible support portion, as well as a plurality of fasteners coupled to the main frame. Each fastener may comprise a mechanism adapted to secure the fastener to the child transport device.
US10046770B1	Systems and methods for estimating a road surface friction coefficient and vehicle lateral velocity using a decoupled dynamical model Systems and methods for independently estimating a road surface friction coefficient value and a vehicular lateral velocity value are provided. In one example, the system includes: a self-aligning torque coefficient estimating module configured to obtain sensor signals from an electronic power steering (EPS) system and an inertial measurement unit and estimate a first self-aligning torque coefficient value based on the sensor signals using a recursive least square algorithm; a road surface friction coefficient value estimating module configured to obtain the estimated first self-aligning torque coefficient value and estimate a first road surface friction coefficient value based on the estimated first self-aligning torque coefficient value; and a feature control module configured to generate one or more control signals configured to control features of a vehicle based on the estimated first road surface friction coefficient value.
US10046768B2	High speed downshift management In order to reduce drivetrain component wear and tear, a machine monitors for an impending downshift and automatically slows the machine to a speed that keeps engine rpm below a target engine rpm before the downshift is completed. A controller in the machine determines the current speed of the machine and then slows the machine to a new speed associated with the target rpm in the new gear. The controller may simply apply the brakes to slow the machine to the new speed independently of the process of changing gears or may actively delay the gear change until the new speed is achieved.
US10046756B2	Method for accelerating a hybrid vehicle A method for accelerating a vehicle driving forward, in which the vehicle has a propulsion system including a combustion engine with an output shaft (2a), a gearbox (3) with an input shaft (3a), an electric machine (9) comprising a stator and a rotor, and a planetary gear comprising a sun gear (10), a ring gear (11) and a planet wheel carrier (12). When accelerating the vehicle the torque of the electric machine is controlled and the rotational speed of the combustion engine is controlled until the components of the planetary gear have the same rotational speed and may be interlocked.
US10046749B2	Brake system and method of operating A vehicle braking system includes a brake pedal, master cylinder, a braking circuit with a wheel cylinder, and a brake pressure generator. A pedal feel simulator is coupled to the master cylinder output side through a switchable valve, the pedal feel simulator providing a reaction force. An isolation valve closes to isolate the braking circuit from the master cylinder and the simulator circuit. A primary pressure sensor generates a braking request signal responsive to the brake pedal. A controller activates the brake pressure generator to apply a braking force to the wheel cylinder based on the braking request signal. The controller identifies an abnormal value from the primary pressure sensor and couples the pedal feel simulator with a secondary pressure sensor within the braking circuit to determine whether the abnormal value indicates a primary pressure sensor malfunction or a malfunction of the pedal feel simulator or the switchable simulator valve.
US10046746B2	Method for piloting a braking system of a vehicle, braking system and vehicle comprising such a braking system A method allows piloting a braking system of a vehicle, the braking system including at least a pair of coupled brake actuators, that includes a pneumatic actuator supplied with a compressed air tank pressurized by a compressor, and an electric actuator. The method includes steps including a) measuring the air pressure of the air tank, b) if the air pressure measured at step a) is inferior to a first threshold value, assessing whether the compressor is able to build up the air pressure of the air tank, c) if the result of the assessment performed at step b) is that the compressor is unable to build up the air pressure of the air tank, operating the braking system in a degraded mode wherein at least the electric actuator is used in case of braking, and d) if the air pressure measured at step a) is inferior to a second threshold value, that is lower than the first threshold value, and if the compressor is unable to build up the air pressure of the air tank, using only the electric actuator in case of new braking actions.
US10046745B2	Cable-traversing trolley adapted for use with impact braking A trolley for traversing a zip line includes a first load-bearing sheave rotatably mounted to one or more side plates, and a second load-bearing sheave rotatably mounted to the one or more side plates and rearward of the first sheave. The trolley also includes an anchor point on the trolley for attaching a payload. When the trolley decelerates, forces acting on the payload create a downward load on the first sheave and the second sheave.
US10046744B2	Brake apparatus An object of the present invention is to provide a brake apparatus capable of acquiring a stable brake performance. A brake apparatus includes a master cylinder configured to be activated according to a brake operation performed by a driver, a reservoir tank divided into at least a first chamber connected to a wheel cylinder via the master cylinder and a second chamber connected to a hydraulic source configured to increase a pressure of brake fluid and transmit the brake fluid to the wheel cylinder, a brake control unit configured to perform brake control of transmitting the brake fluid to the wheel cylinder, and a fluid level detection unit configured to detect a fluid level of the brake fluid in the reservoir tank. The brake control unit is provided so as to be able to perform first brake control of transmitting the brake fluid from the first chamber to the wheel cylinder with use of the master cylinder, thereby increasing a pressure in this wheel cylinder, and second brake control of transmitting the brake fluid in the second chamber to the wheel cylinder with use of the hydraulic source, thereby increasing a pressure in this wheel cylinder. The brake control unit switches brake control between the first brake control and the second brake control according to the fluid level detected by the fluid level detection unit.
US10046738B2	Heated wiper blade for motor vehicles and the like A heated wiper blade for motor vehicles includes an elongated flexible beam and a heating element extending along the beam. The heating element may be configured to provide increased heat at the central portion of the blade and at the opposite ends of the blade. The flexible beam may include curved end portions and a flat or reduced curvature central portion. The heating element is preferably covered and sealed off to prevent loss of heat energy.
US10046734B2	Force-limiting device for a safety belt system A reversible seat belt tensioner including a rotationally operable plastic driven gear (1), and a drive moved with a belt shaft of the belt tensioner. At least one coupling pawl (4) is provided on the drive gear, engaging a gearing of the drive gear upon activation of the reversible belt tensioner, and in a load-transmitting position produces a linkage between the driven gear (1) and the drive gear. A support ring (3) made of a material having a greater strength than the driven gear (1) is provided and is connected to the driven gear (1) for with a projection (21, 22) which into a recess (15, 16) of the driven gear (1). The recess (15, 16) positioned such that the coupling pawl (4) is braced against the driven gear (1) via the projection (21, 22) which engages in the recess (15, 16).
US10046730B2	Support element for absorbing forces in a vehicle A support structure for absorbing forces in a vehicle includes a support element, which encloses a hollow space and includes a number of openings, which is delimited by one or more boundary faces. A receiving body for an assembly unit is inserted in one of the openings so that the receiving body at least partially projects into the hollow space. The receiving body includes a wall which at least in portions runs corresponding to the boundary faces and with which the receiving body makes contact with the boundary faces of the support element.
US10046727B2	Gas generator The present invention provides a gas generator including a cylindrical housing in which an ignition device is attached at a first end portion thereof and a diffuser portion provided with a gas discharge port is attached at a second end portion thereof, an annular end surface being formed on the side of the second end portion, a cylindrical flow path forming member being disposed in the cylindrical housing, an inner space of the cylindrical flow path forming member being partitioned by a partition wall into a first chamber on the side of the first end portion and a second chamber on the side of the second end portion, a space, which includes the first chamber, being a combustion chamber filled with a gas generating agent, and the second chamber forming part of a gas discharge path, in the cylindrical flow path forming member, a first cylindrical space, which is formed between a first wall surface of the cylindrical flow path forming member on the side of the first chamber and the inner wall surface of the cylindrical housing, and a second cylindrical space, which is formed between a second wall surface of the cylindrical flow path forming member on the side of the second chamber and the inner wall surface of the cylindrical housing, being continuous in an axial direction, and the second cylindrical space being a cylindrical space with a length L from a boundary with the first cylindrical space to the annular end surface, and having an annular pocket portion with a length L1 from the annular end surface to the second communication holes, and at least part of a surface of the annular pocket portion being provided with a concave-convex portion.
US10046725B2	Ignition lock An ignition lock for a motor vehicle includes a locking cylinder, which in the presence of a suitable key can be shifted along a path including a punctual directional change between a driving position and a stationary position. In the driving position the ignition lock allows operation of an engine of the motor vehicle. In the stationary position operation of the engine is blocked. An indicating device is controlled by a switch operable by the locking cylinder at the point of directional change.
US10046724B2	Method and apparatus for attaching police push bars A push-bar assembly including a push-bar and a pair of push-bar supports. The push-bar supports are attached by a pair of upper brackets and a pair of lower brackets. The lower brackets include about which a mounting block attached to the push-bar supports pivot when the push-bar assembly is assembled to a vehicle. A clevis bracket and clevis pin are provided on lower bracket assemblies that secure a lower mounting block on the push-bar supports to a pair of lower bracket assemblies.
US10046723B1	Self-adaptive, energy-absorbing bumper A passive energy absorber to be supported by a bumper of a vehicle is disclosed. The passive energy absorber may include a base extending laterally, multiple fins, and multiple stoppers. Each fin may extend longitudinally from the base and be spaced laterally from adjacent fins to form lateral gaps therebetween. Each stopper may form, with a corresponding portion of the base, a triangular prism in a different lateral gap. The base, multiple fins, and multiple stoppers may be formed of polymeric material.
US10046716B2	In-vehicle camera and vehicle control system An in-vehicle camera is provide which has a case and a lens, and which is attached in a vehicle interior so that the lens is exposed at a top face of the case and the top face is opposed to a windshield or another window. The top face has an angular shape bent at a ridge line passing through the top face. The lens is positioned in the vicinity of the ridge line. The in-vehicle camera includes a hood attached to a front portion of the case, the front portion being positioned at a front side of the case with respect to the lens.
US10046711B2	Device for loading two kayaks An arrangement of five supporting elements together with appropriate T-connectors and a four-way connector are employed to provide a device for loading one or more watercraft onto the top of a vehicle. The device is employable with conventional roof rack and kayak cradling structures. The arrangement includes a rotatable mast and boom which may be swung from one side of the vehicle to the other so that hoisting capabilities are available on either side of the vehicle so that multiple watercraft may be easily loaded onto the vehicle with minimal effort by one person.
US10046709B2	Under-seat vehicle compartment having a clamp assembly for engaging a tube support and for absorbing tolerances and movement related noise A storage container for a vehicular seat includes a cushion pan for supporting a cushion. A lateral support bar extends between opposing side members and is positioned below the cushion pan. A container housing is disposed between the opposing side members and is fixedly attached to an underside of the cushion pan. A rear clamp of the container housing defines a containment region within which the lateral support bar is disposed. The rear clamp defines a surface engagement with the lateral support bar and is slidably engaged with the lateral support bar. Generally vertical displacement of the container housing relative to the lateral support bar biases the lateral support bar against the rear clamp to define an absorbing state of the rear clamp that receives at least a portion of the generally vertical displacement of the container housing relative to the lateral support bar.
US10046708B1	System to angularly adjust a trunk floor A system to vary the angle of rotation between two surfaces is presented herein. One general aspect of this system includes a horizontally-oriented fixed surface. The system also includes a planar surface rotatably connected to one side of the fixed surface and configured to substantially cover the fixed surface. The system also includes a raising apparatus affixed to the fixed surface, the raising apparatus operatively connected to the planar surface, the raising apparatus operatively connected to the planar surface, where, based on the amount of downward force being applied to the planar surface, the raising apparatus lowers a portion of the planar surface in relation to the fixed surface so as to reduce the angle of rotation between the planar surface and fixed surface.
US10046706B2	Interior rearview mirror assembly with full screen video display An interior rearview mirror assembly for a vehicle includes a mirror head having a mirror reflective element, and a video display device behind the mirror reflective element and viewable through the mirror reflective element when activated. The video display device includes a display screen that occupies at least 75 percent of a reflective region of the mirror reflective element. The video display device includes a backlighting array of light emitting diodes for backlighting the display screen, and the backlighting array of light emitting diodes includes a plurality of zones of light emitting diodes, with each zone having at least two light emitting diodes. The zones of light emitting diodes are independently controlled based on the video images being displayed by the video display device.
US10046699B2	Advanced warning and risk evasion system and method This invention relates in general to the field of safety devices, and more particularly, but not by way of limitation, to systems and methods for providing advanced warning and risk evasion when hazardous conditions exist. In one embodiment, a vicinity monitoring unit is provided for monitoring, for example, oncoming traffic near a construction zone. In some embodiments, the vicinity monitoring unit may be mounted onto a construction vehicle to monitor nearby traffic and send a warning signal if hazardous conditions exist. In some embodiments, personnel tracking units may be worn by construction workers and the personnel tracking units may be in communication with the vicinity monitoring unit. In some embodiments, a base station is provided for monitoring activities taking place in or near a construction site including monitoring the locations of various personnel and vehicles within the construction site.
US10046698B2	Smartwatch blackbox Techniques are provided for alerting drivers of hazardous driving conditions using the sensing capabilities of wearable mobile technology. In one aspect, a method for alerting drivers of hazardous driving conditions includes the steps of: collecting real-time data from a driver of a vehicle, wherein the data is collected via a mobile device worn by the driver; determining whether the real-time data indicates that a hazardous driving condition exists; providing feedback to the driver if the real-time data indicates that a hazardous driving condition exists, and continuing to collect data from the driver in real-time if the real-time data indicates that a hazardous driving condition does not exist. The real-time data may also be collected and used to learn characteristics of the driver. These characteristics can be compared with the data being collected to help determine, in real-time, whether the driving behavior is normal and whether a hazardous driving condition exists.
US10046696B2	Automatic control systems for vehicles An apparatus for use in a car includes: an input configured to receive data from a sensor; a processor configured to perform a statistical analysis using the data to determine a control parameter for controlling an automatic control of the car; and an output for providing the control parameter for controlling the automatic control of the car.
US10046692B2	Heated light enclosure having an adaptable heating system A heated light enclosure having an adaptable heating system is provided with a controlled heating system to deliver enough heat to a lens on a lamp assembly to remove snow, frost, and/or condensation without overheating the lens. By heating the lens using a combination of one or more of PTC heaters, heat sinks and heat pipes, accumulation of snow, ice, or vapor is mitigated or eliminated from a surface of the lens, thereby enabling light to transmit through the lens. Applications include lamps and bulbs on conveyance devices, including vehicles, boats, planes, and trains, as well as sedentary structures, such as lamp posts, street lights, railroad crossing markers and lights, and airport ground and runway lighting systems.
US10046689B2	Temperature-controlled delivery vehicle In some embodiments, systems, apparatuses and methods are provided herein useful to temperature-controlled delivery of items. A conveyor mechanism disposed within a temperature-controlled compartment of a delivery vehicle can provide easy access to items within the compartment. In some embodiments, the conveyor mechanism can be operated by a control circuit to convey items within the compartment to position the items adjacent to the access door according to various inputs.
US10046685B1	Screen assembly for providing a visual barrier between adjacent seats in a passenger cabin of a vehicle A screen assembly includes an anchor arm, a cover arm, a spool arm, a spool, and a flexible screen. The anchor arm is connected to a component of the vehicle within the passenger cabin. The spool arm is disposed between the anchor arm and the cover arm. The spool is inserted onto the spool arm and can rotate relative to the spool arm. The flexible screen is attached to the spool and includes first and second portions. The first portion has a first edge attached to the spool arm and a second edge attached to the anchor arm. The second portion includes a first edge attached to the spool arm and a second edge attached to the cover arm. The first and second portions are dispensed in opposite directions when at least one of the cover arm and the anchor arm moves relative to the spool arm.
US10046682B2	Back cushion module for a vehicle seating assembly A vehicle seating assembly includes a seating frame defined by a seatback frame and a seat frame. A plurality of distinct assembly modules are configured for attachment with the seating frame. The plurality of distinct assembly modules include a back cushion module, a hard back module, a seat cushion module, and a headrest module. The back cushion module and hard back module are operably coupled together. The headrest module extends over and operably couples the back cushion module with the seat cushion module to substantially encompass the seating frame. The seat cushion module is positioned on the seat frame in front of the seatback frame. First and second side trim pieces are configured to extend over the seat frame concealing side portions of the seat cushion module.
US10046680B2	Four-direction headrest The invention discloses a novel four-direction headrest, which comprises a headrest housing, a U-shaped headrest bar, a Z-direction sliding fixing socket, an unlocking mechanism bracket, a tab, a tab return spring, an X-direction sliding fixing socket, an X-direction sliding guide, an unlocking steel wire, an unlocking button, wherein the locking and unlocking among the X-direction sliding fixing socket, the unlocking mechanism bracket, and the U-shaped headrest bar is realized by the unlocking steel wire, and the locking and unlocking between the tab and the X-direction sliding guide is realized by the tab movement driven by the unlocking steel wire. The locking and unlocking mechanism of the invention is simple, efficient and controllable.
US10046677B2	Seat system for a vehicle A seat system for a vehicle includes a seat having a seat bottom on which a person can sit. An intermediate support structure is secured to the seat and the vehicle which allows the seat to rotate relative to the vehicle. An actuator can interact with the seat to cause the seat to rotate relative to the vehicle. One or more sensors can each measure an aspect of motion. A processor can (i) receive input from each of the one or more sensors, (ii) determine from this input a measure of rotation of the vehicle away from a nominal, level horizontal orientation, and (iii) utilize the input to determine a desired rotation of the seat. An angle that the seat has been rotated away from a nominal, level orientation is more than insubstantially larger than an angle that the vehicle has rotated away from a nominal, level horizontal orientation.
US10046676B2	Child restraint with energy management system A child restraint includes a juvenile vehicle seat including a seat bottom and a seat back. The child restraint also includes an energy dissipater coupled to the seat back.
US10046675B1	Vehicle with slidable seats A vehicle includes a wall having a hanger. The vehicle also includes a floor having a track. A seatback of a seat is supported by the hanger and the track.
US10046673B1	Seat rail end stop A seat assembly including a seat rail having an opening at an end of the seat rail, a seat slider that slides relative to the seat rail along a length of the seat rail, and an end stop at the end of the seat rail that prevents the seat slider from sliding beyond the opening and that substantially covers a cross section of the opening.
US10046670B2	Vehicle seat A vehicle seat is adapted to be moved relative to a floor of a vehicle. The seat includes a seat bottom that can be moved relative to the floor and a seat back that can be moved relative to the seat bottom.
US10046668B2	Drive system for a transportation system A transport system including at least one guideway, at least one levitation generator, at least one lifting member, at least one drive generator, and at least one drive member is presented. The at least one guideway, at least one levitation generator, at least one lifting member, at least one drive generator, and at least one drive member can each be implemented with other systems. The at least one drive generator is configured to: generate a driving magnetic flux; move with a corresponding at least one drive member; and be driven relative to the at least one drive member by the driving magnetic flux. The at least one levitation generator can be configured to: generate a levitating magnetic flux; move within a corresponding at least one lifting member; and elevate above a rest position relative to the at least one lifting member in response to the levitating magnetic flux.
US10046665B2	Coolant passage connection structure and cooler system A coolant passage connection structure includes: a first coolant passage attached to a case which houses a cooler and has a second opening, and extending from the cooler; a second coolant passage that communicates with the second opening; a first connection member connected to the first coolant passage, and having a first opening; a first face seal member; and a second connection member connected to the first opening and the second opening via the first face seal member. The second opening is provided in the case so as to be positioned below the first connection member in a vertical direction. The first connection member is positioned above the first face seal member in the vertical direction and includes a tapered portion that includes an inclined surface inclined further away from a surface of the case toward a lower side in the vertical direction.
US10046664B2	Internal resistance estimation method for secondary battery, output control method for secondary battery, and vehicle An internal resistance estimation method for a secondary battery includes: acquiring an initial internal resistance value and temperature course information including a battery temperature and time information about time at which the battery temperature has been recorded; estimating an increased amount of the internal resistance value after a lapse of a predetermined time from the predetermined reference time on the basis of the temperature course information; estimating a reduced amount of the internal resistance value of the secondary battery resulting from a relative change between a range of use of a state of charge of the positive electrode and a range of use of a state of charge of the negative electrode on the basis of the temperature course information; and calculating an internal resistance variation in the lapse of the predetermined time on the basis of the increased amount and the reduced amount.
US10046662B2	Managing the charging of a battery Disclosed herein is an invention concerning a method for managing charging of a Li-ion battery based on at least one parameter chosen from a group consisting of a state of deterioration of the Li-ion battery and cell unbalance, the method comprising the following steps: a) determining an end-of-charge voltage value of said Li-ion battery, b) generating a control signal controlling the charging of said Li-ion battery, and c) transmitting the control signal to a charger, the control signal being generated in such a way that the Li-ion battery is charged based on the end-of-charge voltage value determined in step a), said end-of-charge voltage value being increased based on the state of deterioration of said Li-ion battery until a limit value is reached, in order to ensure a constant minimal level of required energy in said Li-ion battery is provided at a predetermined reference temperature.
US10046661B2	Detection of on-board charger connection to electric vehicle supply equipment Electric and plug-in hybrid vehicles connect to Electric Vehicle Supply Equipment (EVSE) to recharge a traction battery. Existing standards define the signal interface between the vehicle and EVSE including control pilot and proximity detect signals. The vehicle may use the status of these signals to detect when a connection is established with EVSE. The vehicle may indicate a connection when the signals provide conflicting statuses. The vehicle may prevent driving off and permit charging in the event of a proximity detect signal indicating a state of engagement other than connected as long as a valid control pilot signal is present. The status of the control pilot signal may be utilized to prevent drive-off and permit charging.
US10046660B2	Devices, systems, and methods using reactive power injection for active tuning electric vehicle charging systems Systems, methods, and apparatus are disclosed for wirelessly charging an electric vehicle. In one aspect, a method for transferring power via a magnetic field in a wireless power transfer system is provided. The method includes outputting an alternating electric current to a wireless power transmitter, generating, at the wireless power transmitter, the magnetic field in response to being driven with the alternating electrical current, receiving a value indicative of an electrical characteristic of the wireless power transmitter, and adjusting an operating characteristic of the wireless power transmitter to trigger a change in an electrical current in the receiver, the amount of adjustment selected to cause adjustment of an amount of reactive power in the wireless power transfer system based on changes in the receiver that automatically occur to maintain the output power substantially constant in response to the change in the electrical current in the receiver.
US10046659B2	Systems, apparatus and method for adaptive wireless power transfer An apparatus for wirelessly receiving power from a wireless power transmitter is provided. The apparatus comprises an active switching rectifier operably connected to a coupler and configured to operate in a first bridge mode and a second bridge mode. The apparatus comprises a controller configured to adjust an input resistance of the rectifier to a first value that provides a first wireless power transfer efficiency when the rectifier operates in the first bridge mode. The controller is configured to adjust the input resistance of the rectifier to a second value that provides a second wireless power transfer efficiency less than the first wireless power transfer efficiency while operating within one or more operating limitations when the rectifier operates in the second bridge mode.
US10046658B2	Electrical cable assembly for electric vehicle An electrical cable assembly is provided with an electrical connector sized to be received into an electrical outlet. A cable is in electrical communication with the electrical connector. A lockable connector is in electrical communication with the cable. An adapter receptacle is sized to receive the lockable connector for electrical communication with the lockable connector. The lockable connector is lockable within the adapter receptacle. A vehicle connector assembly is in electrical communication with the adapter receptacle and is sized to be received by a vehicle receptacle to convey current to the vehicle receptacle.
US10046656B2	Bidirectional powering on-board charger, vehicle power supply system including the same, and control method thereof A vehicle power supply system is provided. The system includes a main battery and an OBC having first and second input/output terminals, in which AC power input to the first input/output terminal is converted into DC power to be output to the second input/output terminal, and a magnitude of the DC power input to the second input/output terminal is converted and output to the first input/output terminal. Additionally, the system includes an LDC in which a DC voltage input from the main battery is converted into a low voltage to be supplied to an auxiliary battery or an electronic load and a switching unit is connected between the first input/output terminal and the LDC. A controller is then configured to adjust a powering direction of the OBC and an on/off state of the switching unit, based on whether the main battery is charged and whether the LDC fails.
US10046653B2	Automobile charger A novel automobile charger comprises a direct current (DC) voltage supply, wherein a positive pole of the DC voltage supply is connected with a first end or a first lead of a DC-to-DC module, a first end of a battery voltage detection module and a first end of a load module simultaneously while a negative pole of the DC voltage supply is connected with a second end of the DC-to-DC module, a first end of a microcontroller, a first end of an automobile start control module and a second end of the battery voltage detection module simultaneously. A third end of the DC-to-DC module is connected with a second end of the microcontroller. Third, fourth, and fifth ends of the microcontroller are connected with a third end of the battery voltage detection module, a second end of the automobile start control module and a first end of a load detection module respectively. A second end of the load detection module is connected with a third end of the automobile start control module and a second end of the load module simultaneously.
US10046650B2	Control means and method for charging a vehicle Embodiments of the present invention provide control means for a vehicle, the control means being operable to control charging of tractive energy storage means of the vehicle, the control means being configured to allow charging of the energy storage means in dependence on a location of the vehicle and a time of day, wherein if the location of the vehicle corresponds to one or more prescribed locations the control means is operable to permit charging only during one or more prescribed periods of the day.
US10046643B2	Braking force control apparatus for a vehicle In order to enable satisfactory vehicle motion control to be carried out while wheels (10) are being braked, on a vehicle in which each of the wheels (10) is braked by a regenerative braking force by a motor (30) and a friction braking force by a friction brake mechanism (40), a brake ECU (53) acquires at least one parameter out of a steering angle, a steering velocity, a lateral acceleration of a vehicle body, a yaw rate of the vehicle body, a sprung vertical acceleration, and an unsprung vertical acceleration, and when a magnitude of the parameter is more than a threshold, decreases a ratio of the regenerative braking force out of a driver-requested braking force, and increases a ratio of the friction braking force.
US10046642B2	Control method of dual clutch transmission for hybrid electric vehicle and control system for the same A control method of a dual clutch transmission for a hybrid electric vehicle includes: determining, by a transmission controller, whether a vehicle has entered a power-off down-shift state; determining, by the transmission controller, whether a transmission including a first input shaft, a second input shaft, and an output shaft has entered a torque phase, when the first determining step determines that the vehicle has entered the power-off down-shift state; calculating a compensatory torque for compensating for a change in a regenerative braking force according to a change of a gear ratio in accordance with a completion percentage of the torque phase, when it is determined that a transmission has entered the torque phase; and compensating for regenerative torque of a motor by applying the compensatory torque.
US10046641B2	Mobile power conversion and distribution system A vehicle carries an energy storage system that powers mobility of the vehicle. The vehicle further carries a direct current input coupling to be connected to a direct current (DC) electrical power source, a DC output coupling, an alternating current (AC) input coupling, an AC output coupling, and electronics carried by the vehicle to control both AC and DC voltage and power levels.
US10046638B2	Arrangement for opening and closing an opening in an interior trim piece of a vehicle An arrangement is provided for opening and closing an opening in a covering surface of an interior trim piece in a vehicle via an adjustable cover element. The cover element has two parallel, spaced-apart racks which extend in the adjusting direction of the cover element and each mesh with an associated toothed wheel. The toothed wheels are rotatably mounted on a frame element connected to the interior trim piece and are interlinked by a rotatingly driven shaft; at least one toothed wheel is connected to the shaft for conjoint rotation therewith. The cover element is adjustable relative to the frame element and thus to the opening as a result of a rotation of the toothed wheels that mesh with the racks. Preferably, the cover element slides under the covering surface of the interior trim piece, delimiting the opening, when the opening is opened.
US10046636B2	Saddle type vehicle A saddle type vehicle which can cool a battery efficiently by a simple configuration. The saddle type vehicle includes a battery case accommodating a battery therein and is provided in a space positioned above an engine, which configures part of a power unit, below a seat (occupants' seat) and overlapping with the engine and the seat in an upward and downward direction of a vehicle body. A cooling fan configured to discharge air rearwardly is provided at a rear end of the battery case.
US10046635B2	Powertrain for a hybrid type vehicle The present invention relates to a powertrain for a hybrid type vehicle with a thermal engine (10), notably of internal-combustion type, an electric machine (12) connected to an axle shaft (24) of the vehicle and a transmission device (36) comprising a primary transmission shaft (38) connected to drive shaft (18) of thermal engine (10) through a disengageable coupling (44) and carrying at least two first gear wheels (56, 58) cooperating with at least two second gear wheels (60, 62) carried by a secondary transmission shaft (40) connected to the axle shaft.According to the invention, primary transmission shaft (36) is connected to an auxiliary electric machine (14).
US10046634B2	Engine mount structure An engine mount structure capable of efficiently absorbing vibration input from an engine is provided. The engine mount structure includes a front mount device 20 which is connected to an engine 1 and a subframe 10 to suppress vibration transmission from the engine 1 side to the subframe 10 side. A dynamic damper 26 connected to the subframe 10 to suppress vibration of the subframe 10 is disposed in a hole portion 11b, and an opening of the hole portion 11b is formed in an upper surface portion 11a of a front subframe member component 11 located on a lower side of the front mount device 20.
US10046632B2	Tonneau cover A pickup truck having a tonneau cover is provided. The tonneau cover includes a first panel section pivotable with respect to the opposing first and second upward-extending side walls. A first latching assembly is attached to the first panel section and is configured to selectively secure and release the first panel section with respect to the first and second side walls of the pickup truck. The first latching assembly includes first and second pinch latch assemblies. The first pinch latch assembly is located adjacent the first upward-extending side wall of the pickup truck and the second pinch latch assembly is located adjacent the second upward-extending side wall of the pickup truck.
US10046630B2	Soft front cockpit cover A foldable roof assembly having a soft panel top assembly for a vehicle in sealing engagement with a hard top portion of a roof. The soft panel top assembly has a fixed portion attached to the vehicle and a lightweight pivotal portion that folds back to provide the occupant a quick and easy open air effect. Two door rails of the soft panel top assembly are connected to the vehicle. Two side bows are attached to a first bow member, which is secured to a windshield frame when in a closed position, and are connected at a pivot point created with a bracket attached to the door rails to allow the pivotal portion to pivot to an open position. The soft panel top assembly includes a rear header that is a wireframe and engages with seals in the hard top roof portion to provide a weatherproof seal.
US10046619B2	Dust sensor for vehicle A dust sensor includes: a main body in which a dust inlet is formed and including an optical sensor and a lens for collecting light scattered by dust which enters into the main body through the dust inlet; a button unit protruding outwardly from the main body and having one end that is inserted into a coupling hole formed in the main body, wherein the button unit is selectively moved, by a pushing operation of a user, upward and downward with respect to an interior of the main body in which the lens is installed; and a cleaner installed on the one end of the button unit that is inserted into the main body, wherein the cleaner is repeatedly brought into contact with the lens by the upward and downward movement of the button unit.
US10046615B2	Vehicle height adjustment device A vehicle height adjustment device includes a changer, a vehicle height controller, and a malfunction detector. The changer is drivable when supplied with a current and configured to change a relative position of a body of a vehicle relative to an axle of a wheel of the vehicle. The vehicle height controller is configured to perform such control that a target current set based on the relative position is supplied to the changer so as to control a vehicle height, which is a height of the body of the vehicle. The malfunction detector is configured to detect a failure to make the target current flow to the changer.
US10046614B2	Reinforcing unit Relates to a reinforcing unit and a running gear system with a reinforcing unit, comprising a first shell element and a second shell element, wherein the first shell element and the second shell element each comprise an engagement region on the tube side and an engagement region on the link side, wherein the first shell element and the second shell element each comprise a flange portion, wherein between the flange portion of the first shell element and the flange portion of the second shell element a tensile force can be established, which presses the first and the second shell element against an axle tube in such a manner that the reinforcing unit can be non-positively fixed on the axle tube, wherein the engagement region on the link side can be brought into engagement with a link unit.
US10046609B2	Writer for tire pressure sensor A writer for a tire pressure sensor is disclosed, which is adapted to hold the tire pressure sensor to write a program to the tire pressure sensor. The tire pressure sensor has a first connection port. The writer includes a housing, a positioning member, and an ejection device. A surface of the housing forms a receiving recess, and a second connection port is provided in the receiving recess. When the tire pressure sensor is received in the receiving recess, the first connection port thereof is connected to the second connection port. The positioning member connected to the housing has a block section abutting against the tire pressure sensor to keep the first connection port being connected to the second connection port. The ejection device is adapted to exert a pushing force on the tire pressure sensor to eject it for separating the second connection port from the first connection port.
US10046604B2	Tire crown for heavy civil engineering vehicle Crown of a radial tire for a heavy civil engineering vehicle comprises a tread, a crown reinforcement radially inside of the tread, and a carcass reinforcement radially inside of the crown reinforcement. The crown reinforcement comprises, radially from the outside towards the inside, a protective reinforcement comprising two protective layers comprising elastic metal reinforcers which are parallel to one another within each layer and crossed from one layer to the next, forming respective angles A1 and A2 with the circumferential direction and a working reinforcement comprising two working layers comprising inelastic metal reinforcers, parallel to one another within each layer and crossed from one layer to the next, forming respective angles B1 and B2 with the circumferential direction. Angle B1 is at least equal to 50° and strictly less than 90° and angle B2 is non-zero and at most equal to 12°.
US10046603B2	Pneumatic radial tire Pneumatic radial tire (1) having improved high speed durability and low flatspot feature, and which has polyethylene terephthalate cap ply reinforcement layer (6). The objective is to provide a pneumatic radial tire (1) wherein the pressure on the belt package (5) is increased at high speed and high temperature by increasing the thermal shrinkage force of the cap ply cord.
US10046593B2	Embossing die creation An embossing die is created by printing multiple ink layers (530, 540) in superposition thereby to build up a printed relief pattern (510) in accordance with received design data specifying a design to be embossed. The design data is modified after receipt to introduce into the printed relief pattern to be built, one or more channels (610) which extend depth-wise through multiple ink layers of the printed relief pattern (510) and serve to fully or partially segment the printed relief pattern.
US10046591B2	“Wideback” pamphlet for easy identification on a shelf A pamphlet with a plurality of pages with a placard attached to the fold line of the pamphlet at a plurality of connection points by, staples. The placard attached to the fold line can be pivoted about the fold line to a position perpendicular or parallel to the pamphlet.
US10046589B2	Hybrid security device for security document or token A hybrid security device for security documents and the like, with the microstructure for a first optically variable device (OVD) and the microstructure for a second OVD mutually interlace or interspersed. The first microstructure has a height profile that differs from that of the second microstructure by more than 0.5 microns. Suitable fabrication processes for the hybrid security device are also disclosed.
US10046587B1	Card with container A greeting card having a unique die cut and scored line pattern and a container to be inserted into the binding area of the card. The greeting card and container includes a sheet like element having first, second, third and fourth scored lines forming the binding area, first, second, third, and fourth die cuts creating first and second tabs at the binding area for receiving the container.
US10046580B2	Mounting structure for a plurality of print head units A mounting structure for a plurality of print head units includes a frame; a rigid support mounted on the frame, the support having a plurality of mounting sites each of which is adapted to hold an individual print head unit; and an adjusting system for positional adjustment of the print head units relative to the frame. Each mounting site has at least one adjusting mechanism for individually adjusting, in at least one degree of freedom, a position of the print head unit that is held in that mounting site.
US10046578B2	Image forming device and method for controlling image forming device which compact image data based on an amount of the image data on a next page An image forming device includes an input unit to which image data are input, an image processing unit that performs image processing and generates output data, and an output unit that executes a job on the basis of the output data. The image processing unit, in a vertical width compaction process, recognizes a field enclosed by borders; determines whether the recognized field is a vertical width compaction candidate field; sets a vertical omission band in such a way as to include the blank and part of the border of the vertical width compaction candidate field, without eliminating information; eliminates the vertical omission band of the image data; and shifts and compacts the image data below the vertical omission band in the upward direction.
US10046575B2	Liquid spray device A liquid spray device includes: a liquid spray head including a spray surface provided with a plurality of nozzles that spray liquid to a medium; a conveyance mechanism that includes an opposing surface opposite to the spray surface and conveys the medium in a first direction between the spray surface and the opposing surface; a plurality of protrusions protruding from the spray surface, and arranged in a second direction which is intersecting with the first direction; and a plurality of supports protruding from the opposing surface to support the medium being conveyed, and arranged in the second direction. The protrusions each have at least a part overlapping with a position other than a middle area between the supports adjacent to each other.
US10046573B2	Suction box, system for conveying flat media, and printing machine thus equipped A suction box for a system for transporting flat media (4) includes at least one endless belt (6), formed with a plurality of through-holes, used in a media printing machine (1) equipped with at least one printing unit (2). The suction box includes a suction device (23) to generate a vacuum, a suction compartment (16), divided into at least two distinct chambers (26, 27, 28), including a first suction chamber (28) of variable volume, in communication with the suction device (23) so as to apply the vacuum through the holes in the belt (6) to the media being transported by the belt (6), and a second chamber (26, 27) at ambient pressure. The first and second chambers (28, 26, 27) are separated from one another by a mobile partition (31, 33). The suction compartment (16) has an open upper face equipped with a holding arrangement (14, 43, 44, 46, 47, 48) allowing movement of the belt (6).
US10046566B2	System for cleaning components used to clean inkjet printheads in inkjet printers A system in an inkjet printer cleans components in a printhead cleaning system. The system includes a rectangular frame, an actuator configured with a bi-directionally rotating output shaft, a shaft connected to the rotating output shaft, a rinsing member pneumatically connected to a fluid source to enable a fluid from the fluid source to flow to the member and exit through openings in the rinsing member. Cords are connected to the shaft and the member to move the rinsing member from a first position at one end of the frame to a second position at another end of the frame as the output shaft of the actuator rotates in one direction. Fluid is released through the openings in the rinsing member to clean components of a printhead cleaning system as the rinsing member moves. The actuator is reversed to return the rinsing member to the first position.
US10046563B2	Liquid jet head, method of manufacturing liquid jet head, and liquid jet device A liquid jet head includes a partition separating adjacent grooves, a lower substrate fixing a lower portion of the partition, and an upper substrate installed on an upper end surface of the partition. The partition includes an electrode layer on a surface lower than the upper end surface, the electrode layer including an outer surface approximately perpendicular to the upper end surface, the outer surface continuing to the upper end surface through a first convex curved surface curving outward.
US10046562B2	Wide array printhead module A wide array printhead module includes a plurality of printhead die, each of the printhead die includes a number of nozzles. The nozzles form a number of primitives. A nozzle firing heater is coupled to each of the nozzles. An application specific integrated circuit (ASIC) controls a number of activation pluses that activate the nozzle firing heaters for each of the nozzles associated with the primitives. The activation pulses are delayed between each of the primitives via internal delays and external delays to reduce peak power demands of the printhead die. The ASIC determines the internal delays within each printhead die.
US10046561B2	Printing apparatus and printing method An ink jet printer according to an aspect of the invention includes a heat platen that is capable of heating in a state of supporting recording sheets, a head that discharges ink onto the recording sheets from a nozzle plate in which nozzles are provided, a temperature sensor that acquires temperature information of the nozzle plate, a main scanning portion that performs a main scanning operation that relatively moves the head in a main scanning direction with respect to the recording sheets, a sub-scanning portion that performs a sub-scan operation that relatively moves the recording sheets in a sub-scanning direction, which intersects the main scanning direction, with respect to the head, and a determination portion that determines the necessity of a heating operation, in which the heat platen heats the nozzle plate, on the basis of the temperature information before printing.
US10046560B2	Methods and apparatus to control a heater associated with a printing nozzle Methods and apparatus to control a heater associated with a printing nozzle are disclosed. A method comprising controlling a heater associated with a printing nozzle to reduce a heat output of the heater based on a determination that the printing nozzle is outside a print area and printing an image on a substrate using other printing nozzles while the heat output of the heater is reduced.
US10046559B2	Modules to identify nozzle chamber operation In some examples, a printhead die includes a nozzle to be fired by a fire pulse, and a sensor to measure, during a firing of the nozzle by the fire pulse, a measured signal comprising an impedance characteristic of a fluid sample of the nozzle, in response to an input signal applied to the fluid sample. A comparator is to compare the measured signal to a reference value, and a counter is to count over an evaluation interval in response to the comparing indicating that an evaluation criterion is satisfied, and the counter is to stop counting in response to the comparing indicating that the evaluation criterion is not satisfied, a count value of the counter providing an indicator of nozzle chamber operation corresponding to the measured signal.
US10046554B1	Automatically adjusting nip force in a printing apparatus A feeding system in a printing apparatus is disclosed. For example, the feeding system includes a feed roll, a retard roll, a movable arm, a spring and a temperature dependent flexible material. The movable arm is coupled to the retard roll. The spring is coupled to the movable arm. The temperature dependent flexible material is located below the spring to move the retard roll towards the feed roll via the spring coupled to the end of the arm to maintain a nip force applied by the retard roll against the feed roll as a temperature in a location of the printing apparatus changes.
US10046552B2	Method and apparatus for automated composite-based additive manufacturing An apparatus and method for the automated manufacturing of three-dimensional (3D) composite-based objects is disclosed. The apparatus comprises a material feeder, a printer, a powder system, a transfer system, and optionally a fuser. The method comprises inserting a stack of substrate sheets into a material feeder, transferring a sheet of the stack from the material feeder to a printer, depositing fluid on the single sheet while the sheet rests on a printer platen, transferring the sheet from the printer to a powder system, depositing powder onto the single sheet such that the powder adheres to the areas of the sheet onto which the printer has deposited fluid, removing any powder that did not adhere to the sheet, optionally melting the powder on the substrate, and repeating the steps for as many additional sheets as required for making a specified 3D object.
US10046545B2	Film and decorative film capable of covering article having three-dimensional shape by heat expansion A film capable of covering an article having a three-dimensional shape by heat expansion provided by one embodiment of the present disclosure comprises an outermost layer disposed on an outermost surface, and a polyurethane thermal adhesive layer, which contains a thermoplastic polyurethane selected from the group consisting of polyester-based polyurethanes and polycarbonate-based polyurethanes and is thermally adhered to the article during the heat expansion, wherein the fracture strength of the polyurethane thermal adhesive layer is not less than 1 MPa at 135° C., and the storage modulus at 150° C. and frequency 1.0 Hz is from 5×103 Pa to 5×105 Pa, and the coefficient of loss tan δ is not less than 0.1.
US10046543B2	Laminated film and film attachment method The present invention provides a laminated film that can be easily used by general users and can prevent entry of foreign substances and air bubbles between the attached surfaces even when the film is manually attached in a typical room environment in which foreign substances such as dust are floating; and a film attachment method using such a laminated film. The laminated film includes in the following order: a surface protective film; a foreign-substance-removing adhesive layer; a foreign-substance-removing film; a substrate-attaching adhesive layer; and a functional film, the substrate-attaching adhesive layer exhibiting a higher bond strength with the functional film than with the foreign-substance-removing film.
US10046542B2	Articles and methods for controlled bonding of thin sheets with carriers A method of controllably bonding a thin sheet having a thin sheet bonding surface with a carrier having a carrier bonding surface, by depositing a carbonaceous surface modification layer onto at least one of the thin sheet bonding surface and the carrier bonding surface, incorporating polar groups with the surface modification layer, and then bonding the thin sheet bonding surface to the carrier bonding surface via the surface modification layer. The surface modification layer may include a bulk carbonaceous layer having a first polar group concentration and a surface layer having a second polar group concentration, wherein the second polar group concentration is higher than the first polar group concentration. The surface modification layer deposition and the treatment thereof may be performed by plasma polymerization techniques.
US10046540B2	Light weight temperature resistant transparent laminate structure A transparent laminate structure is provided that includes a front section, a rear section, and a middle section securing the front and rear sections to one another with a gap therebetween. The front section has a strike face formed of an impact resistant layer and a polymer backing layer bonded to the impact resistant layer by an interlayer. The rear section has a forward face comprising at least one polymer layer. The front and middle sections can form an integral subassembly.
US10046537B2	Porous membranes, materials, composites, laminates, textiles and related methods The present invention is directed to novel, improved, modified or treated microporous membranes for use in textile related applications and which are preferably composed of two or more dissimilar porous membrane or material layers laminated together using heat, compression and/or adhesives. The preferred inventive laminated composite microporous membrane is modified using a technique or treatment such as microcreping to introduce permanent small, regularly spaced, crepes, profiles, compactions, pleats, or wrinkles into the laminated composite microporous membrane for the purpose of improving mechanical strength, elasticity and/or resiliency. In addition, the inventive microcreped microporous laminated membrane more preferably has significantly improved ‘hand’ or softness, has ‘next-to-the-skin’ softness, and/or is quiet without crinkling noises during movement, which may be desired performance properties or characteristics of or in textile garments, materials or applications.
US10046535B2	Binding processing device There is provided a binding processing device including: a first pressing member including a convex portion formed by a curved surface with a curvature and protruding toward a sheet bundle; and a second pressing member including a concave portion formed by a curved surface with a curvature and configured to be combined with the convex portion through the sheet bundle, the second pressing member configured to press the sheet bundle sandwiched between the first and second pressing members, wherein in a state where the convex portion of the first pressing member and the concave portion of the second pressing member are combined with each other, a gap is formed between the convex portion and the concave portion in a cross section of the first and second pressing members along a pressing direction, and the gap has a volume larger than a volume of the sandwiched sheet bundle.
US10046534B2	Compaction receptacle A compaction capable receptacle may include a housing with a trash receiving opening, a compaction unit arranged within the housing, and a trash bin arranged within the housing and articulable between a compaction position within the housing and a trash receiving position within the housing, the compaction position aligning the trash bin with a compaction stroke of the compaction unit and the trash receiving position aligning a portion of the trash bin with the trash receiving opening.
US10046526B2	Method for producing a load introducing element A method for producing a load introducing element for a control surface of an aircraft or a spacecraft, includes cutting to size preformed fibrous substructures out of a fibrous material. The method also includes draping the fibrous substructures to mold at least one first component, at least one second component and at least one first flange in the form of a single semi-finished product. Further, the method includes inserting the semi-finished product into a mold, injecting matrix material, and curing the semi-finished product to form a finished product.
US10046521B2	Remotely-accessible additive manufacturing systems and methods A system and method for manufacturing objects in an automated fashion to improve the accessibility and effectiveness of manufacturing technologies. The system may be comprised of one or more web-accessible servers, one or more clients that may communicate with the server, and one or more manufacturing apparatuses that may communicate with one or more clients or servers. The server turns designs into manufacturing instructions using user-specified settings and databases of manufacturing parameters for particular apparatuses and/or manufacturing methods. The system may facilitate communication and revision of designs, manufacturing parameters, or manufacturing instructions between the user and the owner or operator of the manufacturing apparatus. The client may facilitate communication between the server and manufacturing apparatus, may monitor the manufacturing apparatus, and may be physically internal or external to the apparatus.
US10046519B2	Method for producing a three-dimensional object and stereolithography machine employing said method A method for producing a three-dimensional object (11) in layers by using a stereolithography machine (1) that includes: a container (2) containing a fluid substance (3) suited to solidify through exposure to predefined radiation (4a); an emitter (4) suited to emit the predefined radiation (4a) and to solidify a layer of the fluid substance (3) adjacent to the bottom (2a) of the container (2); a modelling plate (5) suited to support the solidified layer (6) and associated with an actuator (7) suited to move it perpendicular to the bottom (2a) of the container; a leveler (8) arranged in contact with the fluid substance (3). The method includes: selectively irradiating the layer of fluid substance to obtain the solidified layer; extracting the solidified layer from the fluid substance; redistributing the fluid substance in the container by moving the leveler so that they are passed between the modelling plate and the container.
US10046514B2	Connection method in addition to a functional part which can be used therefore, and flame-retardant total system produced thereby A connection method, in addition to a functional part used in it and to a flame-retardant total system, connects a single- or multilayer functional part (10) to a third component (20). The functional part (10) has functional elements (14, 16) projecting on one side. The functional part (10) is formed at least partially from a material at least partially transparent to laser light. A blocking layer (18) is disposed to be at least partially opaque to laser light such that after passage of the laser light through the functional part (10), the laser light inside the blocking layer (18) generates heat by absorption for melting the functional part (10) and/or the third component (20) to connect them to one another.
US10046509B2	Method and apparatus for chamfering an end of a pipe made from thermoplastic material Described is a method for chamfering the end of a pipe (2) made from thermoplastic material, comprising the following steps: localized and circumferential heating of an axial portion (3) of the pipe (2) at a predetermined temperature; plastic deformation of the heated axial portion (3) using a tool (4) for forming a chamfer on the axial portion (3).
US10046502B2	Plastic tube screen fills and fabrication thereof The present invention involves a fabrication of plastic-tube-screen-fill using plastic tubes. The plastic-tube-screen-fill consists of several plastic tubes suspended to between top and bottom ring-shaped hole perforated frames in the shape of a rectangular thin plate as a vertical string screen. The top and bottom ring-shaped hole perforated frames are in same configuration to be used in two ways and fabricated by assembling a cup-shaped hole perforated frame and tube-holder-frame. The tube-holder-frame is a male push-fit band connector with several short solid rods positioned and fixed on band for push-fitting into the cup-shaped holes on the cup-shaped hole perforated frame. The solid rod on tube-holder-frame has a male push-fit connector on its lower part to be push-fitted into one edge of tube. The tubes used in the present invention are spiral corrugated tubes. Fabrication and assembling method of perforated frames, tube-holder-frames, and spiral corrugated tubes are described in this invention.
US10046495B2	Multi-component injection-molding machine having a rotatable center part In a three-plate injection-molding machine comprising a nozzle plate, a movable second mold clamping plate, a movable end plate, a closing unit that acts between the end plate and the second mold clamping plate, and a turning unit arranged between the nozzle plate and the second mold clamping plate, rails extend between the nozzle plate and the end plate. The mold-half carrier of the turning unit is supported on a support structure so that it can be rotated about an axis transverse to the machine axis, which support structure forms the abutment for the mold-half carrier rotary drive. The weight of the support structure and mold-half carrier of the turning unit is transferred into the machine bed by means of linear guides, and a substantial part of the reaction torque applied to the support structure is transferred to one of the rails by means of one supporting guide.
US10046489B2	Plastic nut for ball screw and method for manufacturing same In a plastic nut for a ball screw formed by injection molding fiber reinforced plastic, the reduction in precision over time due to wear is minimized. A thread groove is ground until the fibers in matrix plastic are exposed on the surface of the thread groove.
US10046488B2	Method of manufacturing foam molded product, apparatus for manufacturing foam molded product, and foam molded product The present invention is an apparatus for manufacturing a foam molded product in which a foam molded product (1A, 1B) is formed by integrally adhering together a foam body (2) that is formed by the foaming of a foaming raw material, and an air-permeable component (3). A cavity (23) is provided between a plurality of mold components (21, 22, 31) and is defined by respective cavity surfaces (21a, 22a, 31a) of the mold components (21, 22, 31).
US10046487B2	Methods and apparatus for mixing chemical components for the manufacture of polyurethane Embodiments of the invention describe methods and apparatus for mixing chemical components in the manufacture of polyurethane foam. The chemical components include a polyol and different blowing agents. The blowing agents are injected directly into a mixing chamber (100) at different height levels according to their boiling points. The mixing chamber allows continuous discharge of the mixture into a static mixer (400) for further mixing before being stored into a storage tank (600). The blowing agents are chemical compounds selected from the group consisting of hydrocarbon-containing compounds, hydrofluorocarbon-containing compounds or hydrofluoroolefin-containing compounds.
US10046481B2	Component feed nozzle A component feed nozzle includes a housing, which has a component inlet and a component outlet, a piston-shaped closing body, which is slidably supported in the housing and which can be moved back and forth axially. The component outlet is closed by the front end of the closing body in a first position and the component outlet is released or opened in a second position. The component feed nozzle has a membrane seal, which is fastened to the rear end of the closing body and to the housing in such a way that the closing body is completely on one face of the membrane seal. The housing and/or the closing body are designed in such a way that the component reaches all surfaces of the closing body and thus the component pressure is applied to the complete effective surface of the membrane.
US10046480B2	Rock face splitting apparatus and method A splitting apparatus comprising a first splitting blade having a smooth top with a width X and a shoulder angle of less than the friction angle, relative to a point in the middle of the top, and a second splitting blade disposed opposite the first splitting blade, the second splitting blade having a smooth top with a width Y and a shoulder angle of less than the friction angle, relative to a point in the middle of the top.
US10046477B2	Skin stiffness characteristics and loft control production system and method with variable moisture content in input fiberglass media A heating system is provided having a plurality of heated zones, with at least a first zone and a second zone. The first zone receives variable input moisture fiberglass over a first conveyor system and comprises a first compression system above the first conveyor system. Each zone has a fire box at the top and an exhaust stack. Heated air is up drafted through the bottom of the first zone, where the heated air flows from the bottom through the conveyor belt, through the fiberglass media, through the tensioned compression chain, and out the exhaust stack of the first zone. The first zone establishes fiberglass loft, with the second zone providing cure of the fiberglass.
US10046475B2	Machining device and method for producing a master-piece duplicating machine A machining device, including: a cart, for carrying a master-piece and a work-piece; a rail, for allowing manual sliding of the cart along the rail thereabove; a first vice for securing the master-piece, the first vice being fixed to the movable cart; a second vice for securing the work-piece, the second vice being fixed to the movable cart; a limiting element, for limiting the manual sliding of the cart upon meeting of the master-piece with the limiting element; and a protrusion including at least two points extending downwards from the rail; thereby the machining device utilizes parallelism between the channel and a cutting blade of the table saw.
US10046471B1	Vacuum table with individual vacuum chambers A vacuum table for securing a sheet of material. The vacuum table includes a top plate that is porous, a perimeter vacuum chamber disposed beneath a perimeter of the top plate, and interior vacuum chambers bound by the perimeter vacuum chamber and disposed beneath a target area of the top plate that is inside the perimeter of the top plate.
US10046464B2	Device for picking articles A device for picking articles includes a supporting unit and a plurality of gripper heads equipped with respective mechanisms for gripping an article and movable relative to the supporting unit along a picking direction. The gripper heads are divided into at least first gripper heads and second gripper heads. The device includes at least a first picking unit, applied to the supporting unit and on which the first gripper heads are positioned in mutually aligned configuration along a first alignment direction, and a second picking unit, applied to the supporting unit and on which the second gripper heads are positioned in mutually aligned configuration along a second alignment direction transversal to the first alignment direction.
US10046463B1	Passive mechanical system for docking and payload transfer for unmanned underwater vehicles A base member comprising a vertical fin member, a vertical fin stopper surface, a trigger arm recess, and a base guidance slot. A left jaw member comprising a left jaw portion, a left lever portion, a left guidance slot, a left fastening hole, and a trigger release screw. A right jaw member comprising a right jaw portion, a right lever portion, and a right guidance slot. A trigger arm member comprising a trigger hook and a curved trigger end. A top member comprising a top guidance slot, a left spring hole, a right spring hole, a left bottom recess, a right bottom recess, a left spring recess, and a right spring recess. A left spring tension screw received through the left spring hole and a left spring spacer retained in the left spring recess. A bumper member with a bumper surface, a left elongated member, and a right elongated member.
US10046459B2	Three-dimensional visual servoing for robot positioning Three-dimensional visual servoing for positioning a robot in an environment is facilitated. Three-dimensional point cloud data of a scene of the environment is obtained, the scene including a feature. The three-dimensional point cloud data is converted into a two-dimensional image, and a three-dimensional position of the feature is identified based on the two-dimensional image. An indication of the identified three-dimensional position of the feature is then provided.
US10046453B1	Weed trimmer heat shield Armrest heat shield and handheld device systems and methods are shown and described. In one embodiment, the armrest heat shield includes a guard and a clamp. In another embodiment, a handheld device includes an elongated shaft, a gas powered motor, a cutting assembly, and an armrest heat shield aligned sustainably parallel on the shaft above the motor.
US10046450B2	Mode change knob assembly A knob assembly for a power tool comprising: a knob having a slot and knob recess, the slot and knob recess intersecting each other at an intersection within the knob; a latch slideably mounted within the slot; a peg located within the knob recess; wherein the peg and latch engage with each other via the intersection in order for the peg to retain the latch within the slot and for the latch to retain peg within the knob recess.
US10046449B2	Hand tool device A hand tool device has a tool spindle and a hammer mechanism which includes a hammer and at least one curve guide driving the hammer at least during a hammer drilling operation. The tool spindle has at least one bearing surface on which the hammer is movably supported in at least one operating state.
US10046448B2	Fastener driving tool with safety lock A fastener driving tool comprises a hand-held casing having a movable and drivable energy transmission element including a driving member, wherein the driving member acts to drive a fastener, a locking element, and a sensor member for determining an operational state of the fastener driving tool, wherein a driving process is released only if the operational state prevails, wherein the locking member is arranged in a locking manner in a path of the energy transmission element if the non-operational state prevails, wherein, once a driving process has been triggered, the locking member can stop the energy transmission element.
US10046447B2	Method and apparatus for removing a strainer basket from a steam valve A valve strainer basket of an interceptor-type or control-type steam valve is removed from its nested orientation within a counter bore and valve rim of the valve casing. A strong back beam straddles the casing rim over the strainer basket. It is coupled to the strainer basket, such as by engagement of threaded rods into threaded apertures formed in the strainer basket rim. Biasing cylinders, such pressurized fluid cylinders or screw jacks, are interposed between the casing rim and opposite ends of the strong back beam. When the biasing cylinders are actuated, the strong back beam rises, lifting and separating the strainer rim from its nested engagement with the counter bore of the valve casing.
US10046442B2	Vehicle body manufacturing apparatus A vehicle body manufacturing apparatus includes a left side jig configured to be disposed on a left lateral side of a vehicle body, and a right side jig configured to be disposed on a right lateral side of the vehicle body. The left side jig is formed to be divided into a left front jig on a front side and a left rear jig on a rear side, and the right side jig is formed to be divided into a right front jig on a front side and a right rear jig on a rear side. The left side jig and the right side jig performs clamping for positioning and pre-assembling by coming into contact with the vehicle body from the outside of the vehicle body as well as clamping for positioning and pre-assembling by extending into the inside of the vehicle body.
US10046440B1	Sanding apparatus for billiard cue sticks A sanding and smoothing apparatus for pool cue shafts comprises an elongate resilient main body having generally concentrically disposed resilient radially-inner and radially-outer C-shaped members. The apparatus is sized for mating engagement with the tapered shaft of a pool cue received in close fitting conforming relation with the inner surface of the radially-inner C-shaped member. The inner surface of the radially-inner C-shaped member is provided with a suitable abrasive sanding material, which may comprise a sanding sheet or an abrasive coating.
US10046436B2	Delayed diffusion of novel species from the back side of carbide A polycrystalline diamond compact (PDC) is fabricated using a process of delayed diffusion (i.e., post-sintering) of a diffusion species (i.e., a metalloid) introduced from the back side of a carbide further away from the diamond grit or from the flank side of the carbide, as opposed to the side of the carbide adjacent to the diamond grit. The process of fabricating the PDC includes depositing, in a metal container, a synthetic diamond grit, a carbide, and a diffusion species, then applying a high pressure and high temperature (HPHT) to the contents of the metal container wherein (1) the carbide diffuses across the diamond grit, and (2) the diffusion species diffuses across the carbide followed by the diamond grit, thus providing a protective coating to the PDC.
US10046435B2	Grinding apparatus with load control The present disclosure relates to grinding apparatus for grinding the hard metal inserts of rock drill bits, said grinding apparatus having said grinding machine equipped with a grinding cup driven by a motor to rotate about its longitudinal axis wherein the support system comprises an arm or lever system to control vertical movement of the grinding machine and means to provide grinding pressure, wherein the means to provide grinding pressure may be a linear actuator and load cell assembly pivotally connected to the arm or lever system.
US10046422B2	Extrusion piece with insert of dissimilar material A profile piece includes: an extruded piece of a first material having a mouth portion along at least part of its length; and an insert of a second material different than the first material, the insert attached to the extruded piece by the mouth portion, wherein the insert is configured for welding the profile piece to a component of a third material different than the first material.
US10046421B2	Welding apparatus A rotatable gas metal arc welding apparatus comprising: a) a rotatable base; b) a rotation brake; c) a primary welding boom arm; d) at least one secondary welding boom arm rotatably attached to the primary welding boom arm, the at least one secondary welding boom arm being rotatable about a swivel joint so as to be rotatable in a generally horizontal plane; e) a MIG welder station; f) at least one manually operated welding gun connector, each welding gun connector being suspended from a secondary welding boom arm; g) a process controller for controlling a welding gun and the rotation brake; h) a rotatable electrical input connection for connecting electrical power from an external electrical power source to the base; i) an electrical ground connection; and j) a welding wire supply station.
US10046411B2	Modular welding system A welding system includes power conversion circuitry configured to convert input power to weld power and a first housing surface. The first housing surface includes a first mating geometry configured to mate with a first complementary geometry of a first modular surface of a first modular component of the welding system.
US10046407B2	Wire electric discharge machine for taper-machining tilted workpiece In a wire electric discharge machine, a workpiece mounting unit mounts a workpiece tilted at a preset angle to a plane based on two orthogonal axes, X- and Y-axes. An XY-coordinate system is tilted at the preset angle so that it is transformed into an X′Y′-coordinate system. A machining command value commanded by a machining program is corrected based on the X′Y′-coordinate system. Thus, the tilted workpiece is taper-machined with a wire electrode kept substantially perpendicular to the XY-plane (table surface).
US10046404B2	Workpiece guard and blade guard for band saw A hand-held band saw for cutting a workpiece. The hand-held band saw includes a deck, first and second wheels coupled to the deck for receiving a continuous blade thereabout, a motor coupled to the deck for driving at least one of the first or second wheels, and a handle providing a grip for a user to hold the band saw. The band saw also includes a blade guard having a first portion adjacent the first wheel, a second portion adjacent the second wheel, and a third portion adjoining the first and second portions. A joint couples the first, second, and third portions to the deck for simultaneous movement of the first, second, and third portions with respect to the deck.
US10046401B2	Hole saw guide device A guide for a hole saw for making a new larger hole in a work piece with an existing hole, the guide comprising a base sized to span the existing hole, the base comprising a central aperture, a plurality of discrete first contact surfaces for abutting an interior cylindrical wall of the existing hole, and a plurality of discrete second contact surfaces for abutting an exterior surface of the work piece surrounding the existing hole; the plurality of discrete second contact surfaces being substantially co-planar and being substantially perpendicular to the plurality of discrete first contact surfaces; a shaft having a first end sized to be received in an arbor of the hole saw and a second end to be slidably and rotatably received through the central aperture of the base; and the base biased to be located at or near the second end of the shaft.
US10046397B2	Diamond coated tool The diamond coated tool of the present invention is a diamond coated tool including a base material and a diamond layer coating a surface of the base material, and characterized in that the surface of the base material has an arithmetic average roughness Ra of not less than 0.1 μm and not more than 10 μm and an average length of roughness profile elements RSm of not less than 3.1 μm and not more than 5.4 μm, and that the diamond layer has a plurality of cavities at a portion bordering on the base material.
US10046396B2	Cutting insert, cutting tool, and method for manufacturing machined product The cutting insert is provided with: a top surface, a bottom surface, a side surface, a cutting edge located at the intersection portion of the top surface and the side surface; a through hole located from the top surface to the bottom surface; a projecting portion extending from a corner section to a through hole side; and a rake surface located between the cutting edge and the projecting portion. A boundary line between the rake surface and the projecting portion comprises a first end. In a top view, a bisector of the corner section intersects the cutting edge at a first point and intersects a top edge section of the through-hole at a second point. The first end is located closer to the through-hole side than a perpendicular line that passes through a midpoint of a line segment connecting the first point and the second point.
US10046395B2	Laminated film for packaging Disclosed is a sustainable plastic laminated film particularly for packaging soap bars by envelope wrapping method. Disclosed is a laminated film for packaging comprising: (i) a first layer of polyester; (ii) a second layer of polyester; and, (iii) an intermediate layer comprising polyethylene therebetween wherein thickness of the intermediate layer having polyethylene is less than thickness of either of the adjacent layers of polyester. It has been determined that at least some technical problems pertaining to adaptability on packaging machines can be overcome by introducing the intermediate layer having polyethylene between the two layers of polyester.
US10046394B2	Method for manufacturing overhanging material by pulsed, voxel-wise buildup A method for manufacturing material voxel-by-voxel using directed-energy deposition is given. Using the method, unsupported structures, via voxel-wise directed-energy deposition, with steep overhangs is described and demonstrated. Methods for forming arbitrarily-complex structures and shaped voxels and surfaces are also given. A method for forming materials with internally-varying properties is also given. The method utilizes a pulsed or modulated, rather than continuous-wave energy source, thus allowing rapid solidification of voxels, rather than contours, hatches or tracks. Tuning of pulsing or modulation, material flow, and deposition-path parameters allows the buildup of unsupported material using standard directed-energy deposition processing heads and 3-axis stages, for example. The methods are demonstrated using a modified-directed-energy-deposition processes and is applicable to powder-bed for the buildup of three-dimensional components, repair and the addition of features to existing components.
US10046392B2	Crack-free fabrication of near net shape powder-based metallic parts Crack-free powder-based, near net shaped parts are fabricated using a die assembly and cold isostatic pressing. Soft materials are introduced on both sides of die components in order to balance compression loads applied to the die component, and thereby avoid deformation of the die component.
US10046389B2	Method and assembly for forming components having internal passages using a jacketed core A method of forming a component having an internal passage defined therein includes forming a precursor core having a shape corresponding to a shape of the internal passage, and forming a hollow structure around the precursor core. The method also includes removing the precursor core from within the hollow structure, and disposing an inner core within the hollow structure to form a jacketed core. The method further includes positioning the jacketed core with respect to a mold, and introducing a component material in a molten state into a cavity of the mold, such that the component material in the molten state at least partially absorbs the hollow structure from a portion of the jacketed core within the cavity. Additionally, the method includes cooling the component material in the cavity to form the component. The inner core defines the internal passage within the component.
US10046388B2	High-strength structural elements using metal foam for portable information handling systems Methods for manufacturing a metal foam and a metal foam reinforced back plate may be used to provide high-strength and low weight structural elements in portable information handling systems. A method for manufacturing a metal foam may include selectively adding iridium oxide and ceramic particulate to a light-metal allow to create desired mechanical properties of the metal foam.
US10046385B2	Die cast component and a method for producing a die cast component The present invention provides a die cast component, in particular a water outlet fitting, containing a base body (1) produced from metal or a metal alloy by the die casting method and having a cavity in which a number of openings (2, 3, 4) are provided by which the cavity is accessible from the outside, the cavity being at least partially filled with a casting core (5) that is in two-dimensional contact with the inside of the base body (1) and in which at least one channel (6) is provided for the conveyance of fluid, the casting core (5) being made of a material the melting point of which is lower than the melting point of the material from which the base body (1) is produced, and that the outside of the casting core (5) rests with at least substantially all of its surface against the inside of the base body (1). Furthermore, the invention also provides a method for producing this type of die casting component.
US10046383B2	Cu—Sn coexisting steel and method for manufacturing the same A method for manufacturing Cu—Sn coexisting steel produces a good quality surface even after hot rolling. The steel is manufactured by continuous casting a molten steel that contains C: 0.04 to 0.20%, Si: 0.05 to 1.00%, Mn: 0.20 to 2.50%, P: no more than 0.05%, S: no more than 0.02%, Cu: 0.20 to 1.50%, Sn: 0.06 to 0.50%, Al: 0.06 to 1.00% and Ni: 0.05 to 1.00% by mass, and Fe and impurities as the remainder. The composition of the molten steel is defined as [Al]/(3[Si]+[Mn])≥0.050, [Ni]/([Cu]+5[Sn])≥0.10 and [Al]/[Ni]≥0.20 if the content of an element X in the molten steel is represented as [X], an internal oxidation layer is formed in a process of cooling a slab, and Al2O3 is contained by the internal oxidation layer.
US10046381B2	Metrology-based system for operating a flexible manufacturing system A method and apparatus for positioning an end effector relative to a fuselage assembly. A configuration of the fuselage assembly may be determined. The end effector may be positioned relative to the fuselage assembly based on the configuration determined. A set of actual reference locations may be identified for a set of reference points on the fuselage assembly. The end effector may be positioned at an operation location based on the set of actual reference locations identified.
US10046380B2	Twist application device with an adjustable distance between the conductor ends A twist application device, including a feeder (1) for feeding conductor ends (2a . . . 2c) of at least two conductors (3a . . . 3c), and a rotatably mounted twist application head (4) for twisting the said conductors (3a . . . 3c). The twist application device also includes a controller (7), connected with a drive (8) for first clamping jaws (5a . . . 5f) of the feeder (1), and is equipped for control of the latter. The distance (a) between clamped conductor ends (2a . . . 2c) is set at an adjustable value before the transfer of the conductor ends (2a . . . 2c) from the feed device (1) into the twist application head (4). A method of twisting at least two conductors (3a . . . 3c), in which the referred-to distance (a) is set at an adjustable value before clamping of the conductor ends (2a . . . 2c) in the second jaws (6a, 6b) of the twist application head (4). In alternative aspect, a feed device (1) for feeding conductor ends (2a . . . 2c) of conductors (3a . . . 3c) into a further processing device (4). The feed device (1) has first clamping jaws (5a . . . 5f), and the further processing device (4) has second clamping jaws (6a, 6b) for accepting and clamping the conductor ends (2a . . . 2c). The first jaws (5a . . . 5f) in a clamping position can be relatively moved so that distance (a) between ends (2a . . . 2c) may be altered. An intermediate space, located between first jaws (5a . . . 5f), extends, in a direction of movement (A) for altering the distance between clamped ends (2a . . . 2c), at least twice as far as in a clamping direction (B). Also a method, in which a variable position of the first jaws (5a . . . 5f) is adjusted in accordance with a selected distance (a) between the ends (2a . . . 2c) before clamping of the ends (2a . . . 2c), and the first jaws (5a . . . 5f) are moved into a prescribed position before the clamping of the ends (2a . . . 2c) in the second jaws (6a, 6b) of the further processing device (4).
US10046379B1	Heat exchanger fin forming machine What is disclosed is a fin forming machine for making fins for heat exchanger cores, or the like, in which the fin forming machine has three major drives and separate controls; the top and bottom drives control the vertical opening and closing of fin forming dies under programmable control in accordance with CNC technology; and a center drive under the control of a separate programmable system which controls horizontal movement of the feedstock into intersection with the top and bottom forming dies to incrementally halt the movement of the feedstock as it intersects with the forming dies upon convergence during fin formation and then advances it a controllable distance for the next fin forming action. These three drive systems being seamlessly variable and controllable during operation, maintain a high degree of calibration of the formation of each fin to maintain fin height and spacing within very close tolerances, which calibrations are achieved without shutting down machine operation. Positive control of all drive systems minimizes overtravel of the forming dies.
US10046370B2	Substrate processing apparatus, substrate processing method, fluid supplying method and storage medium The present disclosure provides a substrate processing apparatus including: a processing chamber configured to process a substrate; a fluid supply source configured to supply a substrate processing fluid used in processing for the substrate in a predetermined pressure; a constant pressure supplying path configured to supply the substrate processing fluid from the fluid supply source to the processing chamber in a predetermined pressure without boosting the pressure of the substrate processing liquid; a boosted pressure supplying path configured to boost the pressure of the substrate processing fluid from the fluid supply source into a predetermined pressure by a booster mechanism and supply the pressure boosted substrate processing fluid to the processing chamber; and a control unit configured to switch over the constant pressure supplying path and the boosted pressure supplying path.
US10046368B2	Device and method for processing metal parent parts and for sorting metal waste parts A device and a method for processing parent parts and for sorting waste parts thereby separated. For this purpose, an optical detection unit is provided, which is configured to detect at least one geometric feature G of each waste part and to generate a control signal S corresponding to the at least one detected geometric feature G. The control signal S is transmitted to a sorting unit. The fed waste part is sorted depending on the received control signal S. It is thus possible to assign the separated waste parts to a specific parent part. This in turn enables an assignment and determination of the material of which the waste part consists, which specifically corresponds to the material of which the parent part consists. This enables the waste parts to be separated into different categories.
US10046363B2	Injection molded screening apparatuses and methods Screening members, screening assemblies, methods for fabricating screening members and assemblies and methods for screening materials are provided for vibratory screening machines that incorporate the use of injection molded materials. Use of injection molded screen elements provide, inter alia, for: varying screening surface configurations; fast and relatively simple screen assembly fabrication; and a combination of outstanding screen assembly mechanical and electrical properties, including toughness, wear and chemical resistance. Embodiments of the present invention use a thermoplastic injection molded material.
US10046362B2	Vibration generating unit, vibrating body unit, and ultrasonic treatment apparatus A vibration generating unit includes a proximal side vibration transmitting section extended from a proximal end of the ultrasonic transducer toward a proximal direction. A proximal end of the proximal side vibration transmitting section is placed at a position apart from a reference antinode position toward the proximal direction by an extending dimension equal to an integral multiple of a half wavelength, when the reference antinode position is the closest to the ultrasonic transducer among antinode positions placed on the proximal direction side with respect to the ultrasonic transducer. The vibration generating unit includes an amplitude increasing section increasing an amplitude of the ultrasonic vibration transmitted toward the proximal direction in the proximal side vibration transmitting section.
US10046361B2	Painting method and painting installation for painting a component with a character edge A component is conveyed in a conveyor direction through a painting installation by conveyor. The component surface of the component to be painted is subdivided into surface painting modules which lie one behind the other in the conveyor direction. The individual painting modules of the component surface are painted one after the other using a multi-axis painting robot that has an atomizer.The painting robot guides the atomizer, within each one painting module, along a painting path and across the component surface of the painting module. The painting path has at least one path section running transverse to the component edge.Within the painting module, the painting path can comprise at least one path section that runs substantially parallel to the component edge.
US10046357B1	Texturing a wall or ceiling with non-acoustical joint compound A method of texturing a wall or ceiling with non-acoustical joint compound by providing a collapsible bag having an opening at its top and is adapted to contain non-acoustical joint compound for forming a textured coating on the wall or ceiling and providing a spray nozzle having a low pressure input port, a joint compound suction port attached to the opening at the top of the collapsible bag, and an output port for spraying the non-acoustical joint compound. A low pressure stream of air from an air gun attached to the low pressure input port urges a small quantity of the non-acoustical joint compound to be sprayed out of the spray nozzle when the bottom of the collapsible disposable bag is raised above its top to either allow or force the joint compound to flow into the suction port and into the interior of the spray nozzle.
US10046354B2	Blade device, and printer and coating apparatus provided with said blade device Provided are a blade device equipped with a blade member which can accurately adjust pressing force due to a blade member, and a printing machine and a coating device equipped with the blade device. A blade device according to the present invention has: a blade member contacting with a plate roll to which coating material is to be applied; an upper holder contacting with the blade member from one surface side of the blade member; a lower holder contacting with the blade member from another surface side of the blade member; a tube contacting with the blade member and configured to expand and contract by pressure of fluid; and a tube positioning part which is provided on the upper holder and positions the tube closer to the roller, in a direction in which the blade member extends, than a tip end of the lower holder is. The tube adjusts a pressing force, of the tip end of the blade member, against the roller by being expanded or contracted while being held by the tube positioning part and the blade member.
US10046350B2	Systems and methods for controlling water temperature in toilets and bidets A process includes setting a preset temperature; setting up a counter, wherein a first number is displayed on the counter in response to a water control switch switching from a low position to a high position, a second number is displayed on the counter in response to the water control switching from the high position to the low position; setting a target temperature in response to a first determination as to whether the first number or the second number is displayed on the counter, wherein the target temperature is equal to the preset temperature in response to the first number being displayed and the target temperature is equal to preset temperature less an adjustment temperature in response to the second number being displayed; and maintaining the target temperature for a period of time, then restoring the target temperature to the preset temperature after the period of time.
US10046348B2	Metering dispenser for discharging an in particular pasty or viscous material, such as cosmetic creams, adhesives and the like The invention relates to a metering dispenser for putting out pasty or viscous material, comprising a dispenser housing, a cartridge arranged therein, an applicator and a pump unit. The metering dispenser according to the invention is provided with an actuating device which is formed by a push button, wherein the pump unit is activated by pushing the push button into the housing in order to put out the material.
US10046341B2	Shower system combining a top sprayer and a hand shower A shower system includes a top sprayer with at least two water types and a hand shower. The top sprayer is disposed with an inlet waterway to connect to the water source and first diversion waterways corresponding to the water types one by one; wherein the top sprayer is further disposed with a second diversion waterway, the hand shower is connected to the second diversion waterway by an external flexible pipe; the top sprayer is disposed with a switch mechanism, the switch mechanism is cooperated to the inlet waterway, the first diversion waterways and the second diversion waterway to switch the waterways, thus switching any diversion waterway to connect to the inlet waterway.
US10046338B2	Centrifugal liquid separating system and method A centrifugal liquid separating system broadly comprises an insert cartridge including a housing, an inlet, one or more flow guides, a stator, a compression nozzle, an expansion nozzle, and an outlet. The flow guides guide liquid flowing into the inlet past the stator into the compression nozzle. The stator induces a rotational vortex into the liquid flow. Liquid with heavier particles in the liquid flow is urged to the outside of the rotational vortex. Liquid with lighter particles and cleaner liquid is urged to the inside of the rotational vortex. The compression nozzle and the expansion nozzle are aligned to cooperatively form an annular liquid channel. The liquid with the heavier particles flows through the annular liquid channel and the liquid with the lighter particles and the cleaner liquid flows to the expansion nozzle to the outlet.
US10046335B2	Centrifuge for pivoting the rotating shafts of the sample container and swing rotor for centrifuge A centrifuge including a lid section of a sample container, the lid section having a rotating shaft for swinging, and a swing-type rotor, and the centrifuge conducts centrifugation operation in a state where the sample container is seated in a bucket housing section by making the sample container in which the rotating shaft is mounted to a rotating shaft engagement groove of the rotor swing due to the rotation of the rotor. The rotating shaft comprises a plurality of members connected by a connection section and is configured so as to be bendable at the connection section by a centrifugal load accompanying the rotation of the rotor.
US10046328B2	Jaw crusher driving device Provided is a jaw crusher driving device in which a driving torque can be transmitted reliably to a rotation driving shaft to perform a crushing operation by strongly fixing a hydraulic pressure motor between a body frame of a jaw crusher and a flywheel. The jaw crusher includes a fixed tooth, a movable tooth, a rotation driving shaft rotatably supported on a body frame, and a pair of flywheels provided in the rotation driving shaft. The driving device includes: a hydraulic pressure motor in which a rotation shaft portion can rotate in relation to a motor body when pressure fluid is supplied; a connector for connecting one flywheel of the pair of flywheels and the rotation shaft portion; and a torque arm provided between the body frame and the motor body so as to prevent the motor body from rotating about an axis of the rotation driving shaft.
US10046322B1	Reaction well for assay device This disclosure relates to an apparatus for simultaneously filling a plurality of sample chambers. In one aspect, the apparatus comprises a common fluid source and a plurality of independent, continuous fluidic pathways. Each independent, continuous fluidic pathway comprises a sample chamber and a pneumatic compartment. The sample chamber is connected to the common fluid source, and the pneumatic compartment is connected to the sample chamber. The sample chamber comprises, in part, an assay chamber. The assay chamber comprises a monolithic substrate and a plug. In some embodiments, the assay chamber contains a magnetic mixing element. In some embodiments, the assay chamber is a double tapered chamber. In some embodiments, a ratio of a volume of the sample chamber to a volume of the pneumatic compartment is substantially equivalent for each fluidic pathway of the plurality of fluidic pathways.
US10046318B2	Ligand components, associated reaction products, activated reaction products, hydrosilylation catalysts and hydrosilylation curable compositions including the ligand components, and associated methods for preparing same A ligand component is formed according to formula (1):R12P—X—N═C(R2)—Y, wherein R1 is Ph or Cyc or a C1-C20 substituted or unsubstituted ailkyl group; each Ph is a substituted or unsubstituted phenyl group; each Cyc is a substituted or unsubstituted cycloalkyl group; X is an unsubstituted arylene or a C2-C3 substituted or unsubstituted alkylene; R2 is H, methyl or Ph; and Y N is pyridyl, 6-phenylpyridyl or 6-methylpyridyl; with the proviso that when X is a C2 substituted or unsubstituted alkylene and Y is pyridyl, R2 is methyl or Ph. A reaction product including the ligand component and a metal precursor is prepared by combining the ligand component with the metal precursor. An activated reaction product is formed by activating the reaction product as a hydrosilylation catalyst.
US10046316B2	Zeolite An object of the present invention is to provide an AFX zeolite having a novel structure. An AFX zeolite having a lattice spacing d of a (004) plane being not less than 4.84 Å and not greater than 5.00 Å, and a molar ratio of silica to alumina being not less than 10 and not higher than 32. Such an AFX zeolite can be produced by a production method comprising a crystallization step of crystallizing a composition at a temperature of not lower than 160° C.; the composition containing a silicon source, an aluminum source, a 1,3-di(1-adamantyl)imidazolium cation, and an alkali metal; a molar ratio of hydroxide ions to silica being less than 0.25 or a molar ratio of silica to alumina being not higher than 27; and a molar ratio of the 1,3-di(1-adamantyl)imidazolium cation to silica being less than 0.20.
US10046315B2	Crystalline transition metal molybdotungstate A hydroprocessing catalyst has been developed. The catalyst is a unique transition metal tungstate material. The hydroprocessing using the crystalline transition metal molybdotungstate material may include hydrodenitrification, hydrodesulfurization, hydrodemetallation, hydrodesilication, hydrodearomatization, hydroisomerization, hydrotreating, hydrofining, and hydrocracking.
US10046310B2	Catalytic converters with age-suppressing catalysts A catalytic converter includes a catalyst. The catalyst includes a supporting oxide layer. The catalyst also includes platinum group metal (PGM) particles partially embedded in the supporting oxide layer such that a portion of each PGM particle is surrounded by the supporting oxide layer and an other portion of each PGM particle remains exposed.
US10046303B2	Disassemblable stacked flow reactor A plate-type flow reactor device with a first plate (20) having first and second opposing surfaces (22, 24) and one or more through-holes (26); a second plate sealed against the first surface (22) by at least two first O-rings (50); a third plate (40) sealed against the second surface (24) by at least one second O-ring (60); two or more first elongated channels (70) defined between the first surface (22) and the second plate and one or more second elongated channels (80) defined between the second surface (24) and the third plate, wherein each first channel communicates with the at least one second channel (80) via one or more of the through-holes (26) through the first plate (20), and said one first channel (70a) communicates with another first channel (70b) of the two or more first channels (70) only via said at least one second channel (80), and each first channel (70) is individually surrounded by at least one of the first O-rings (50) and the at least one second is individually surrounded by the at least one second O-ring (60).
US10046291B2	Method for manufacturing microcapsules The present invention provides a process for producing microcapsules capable of retaining an organic compound as an active ingredient such as fragrance materials therein over a long period of time. The present invention relates to process for producing microcapsules, which includes step (1) of emulsifying an organic phase including at least one organic compound and a tetraalkoxysilane such that a content of the tetraalkoxysilane in the organic phase is not less than 10% by mass and not more than 60% by mass on the basis of the organic compound, in a water phase inducing a surfactant, and subjecting the resulting emulsion to a sol-gel reaction under acidic conditions to form capsules each including the core and the first shell; and step (2) of further adding a tetraalkoxysilane to a water dispersion containing the capsules obtained in the step (1), and subjecting the obtained mixture to a sol-gel reaction while maintaining an initial pH value in the sol-gel reaction of the step (2) below an initial pH value in the sol-gel reaction of the step (1) to form the capsules each including the second shell encapsulating the first shell.
US10046289B2	Method for replacement of phosgene synthesis column catalyst The present invention discloses a method of quickly desorbing phosgene from a catalyst in a phosgene synthesizing tower when the catalyst in the phosgene synthesizing tower is replaced. The method is carried out by first purging out easily-desorbed phosgene from the catalyst activated carbon in the phosgene synthesizing tower with nitrogen gas, then purging with ammonia gas, and the ammonia gas is reacted with the hardly-desorbed phosgene in the catalyst of the phosgene synthesizing tower. Then the phosgene synthesizing tower is rinsed with a water gun and then dried with hot gas. The phosgene content at an outlet of the phosgene synthesizing tower after purging is below 0.5 ppm, which can significantly save the time of the phosgene synthesizing tower for purging the phosgene, greatly reduce the amount of nitrogen gas consumed, and improve the safety of the process operation.
US10046288B2	View definition enhancement system and method for gastrointestinal endoscope diagnosis and treatment A view definition enhancement system for gastrointestinal endoscope diagnosis and treatment (ESCGV) comprises a washing bottle (1) and a liquid delivery pipe (2) led out from the washing bottle (1). The liquid delivery pipe (2) pumps washing liquid to a liquid inlet system of a gastrointestinal endoscope or an observation window of the gastrointestinal endoscope through a first peristaltic pump (3); and the washing bottle (1) is further provided with a stirring and heating subsystem capable of stirring and heating the washing liquid. A view definition enhancement method for gastrointestinal endoscope diagnosis and treatment comprises steps of: 1) adding the washing liquid into the washing bottle (1); 2) magnetically stirring the washing liquid in the washing bottle (1), and heating the washing liquid at the same time; 3) setting the temperature of the washing liquid to 25-38° C.; and 4) delivering the washing liquid into the observation window of the gastrointestinal endoscope. The ESCGV can enhance the view definition under the gastrointestinal endoscope, make the operation simple and convenient, reduce the missed diagnosis and erroneous diagnosis, and improve the treatment quality of the gastrointestinal endoscope.
US10046285B2	Polymer functional film and method for producing same The present invention provides a polymer functional film obtained by polymerizing and curing a composition including (A) a styrene-based monomer represented by Formula (HSM); (B) a crosslinking agent represented by Formula (CL); and (C) a polymerization initiator represented by Formula (PI-1) or (PI-2), and a method for producing the same: in which R1 represents a halogen atom or —N+(R2)(R3)(R4)(X1−); n1 represents an integer from 1 to 10; here, R2 to R4 each independently represent a particular substituent; X1− represents an organic or inorganic anion; L1 represents an alkylene group or an alkenylene group; Ra, Rb, Rc and Rd each independently represent a particular substituent; n2 and n4 each independently represent an integer from 1 to 10; X2− and X3− each independently represent an organic or inorganic anion; and R5 to R10 each represent a hydrogen atom or a particular substituent.
US10046284B2	Compatibilized immiscible polymer blends and molecular sieve membranes thereof In some aspects, the present disclosure provides a polymer composition which comprises two polymer molecules and a compatibilizing agent. In some embodiments, the polymer composition is useful for the preparation of membranes used in the separation of two or more gases. In some embodiments, the polymer composition comprises a polyimide polymer and a polybenzimidazole polymer which have been compatibilizing with a small molecule or a metal organic framework.
US10046281B2	Monofilament-reinforced hollow fiber membrane with scalloped lumen A hollow fiber membrane is formed by embedding a braid having a spiral open weave of monofilaments only, to avoid a “whiskering” problem. The open weave is characterized by contiguous, circumferential, rhomboid-shaped areas of polymer film separated by monofilament. When the braid is supported on a plasticized PVA cable having a scalloped periphery, the braid can be infiltrated with membrane polymer which, when coagulated, embeds the braid positioning it around the lumen. The embedded spiral weave, free of any circumferentially constricting monofilament, allows the membrane to be biaxially distensible. The membrane has “give” not only in the axial or longitudinal direction but also in the radial direction. “Give” in the radial direction permits soiled membranes to be backwashed under higher pressure than in a comparable braid which is not radially distensible.
US10046279B2	Curable compositions and membranes A curable composition comprising the components (i) 0 to 60 wt % non-ionic crosslinker(s); (ii) 20 to 85 wt % curable ionic compound(s) comprising an anionic group and at least one ethylenically unsaturated group; (iii) 15 to 45 wt % solvent(s); (iv) 0 to 10 wt % of photoinitiator(s); and (v) 2 to 45 wt % of structure modifier(s); wherein the molar ratio of component (v): (ii) is 0.25 to 0.65. The compositions are useful for preparing membranes for (reverse) electrodialysis.
US10046275B2	System and method for improving the performance of a selective catalyst reduction system in a heat recovery steam generator A heat recovery steam generator includes a gas inlet for receiving a flow of exhaust gas from a gas turbine, a gas outlet opposite the gas inlet and configured to transport the flow of exhaust gas to atmosphere, and a sorbent injection device intermediate the gas inlet and the gas outlet, the sorbent injection device including at least one injection port configured to inject a sorbent into the flow of exhaust gas. The sorbent is configured to react with an acid gas within the flow of exhaust gas to neutralize the acid gas and inhibit the formation of salt deposits.
US10046273B1	Systems and method for removal of acid gas in a circulating dry scrubber Systems and methods for the use of highly reactive hydrated lime (HRH) in circulating dry scrubbers (CDS) to remove sulfur dioxide (SO2) from the flue gas.
US10046271B2	Air cleaner for fuel cell system An air cleaner for a fuel cell system includes a housing, a first filter, and a second filter. The first filter is arranged inside the housing and collects dust contained in air. The second filter is arranged side by side with the first filter in an air flowing direction inside the housing and adsorbs impure gas contained in air. The first filter includes a filtering member, which has nonwoven fabric and filter paper adhered to the nonwoven fabric. The filter paper is located on a downstream side in the air flowing direction of the nonwoven fabric and has a higher packing density than the nonwoven fabric. The second filter includes a base member having a honeycomb structure with through-holes and adsorbent, which is provided on inner surfaces of the through-holes and adsorbs the impure gas.
US10046270B2	Method for operating an air-drying device for drying air, air-drying device for drying air as well as compressed air system A method for operating an air-drying device (10) and an air-drying device (10) are provided. The air-drying device (10) has at least one adsorption device (20) with a first adsorption section (21), a second adsorption section (22), an air feed line (11), an air removal line and an analysis unit (13). The first adsorption section (21) and the second adsorption section (22) can be used alternatingly to dry air (70). The air feed line (11) feeds air (70) to be dried and is connected to an inlet opening (24) of the adsorption device (20) in a fluid-communicating manner. The air removal line (12) removes dried air (70) and is connected to an outlet opening (25) of the adsorption device (20) in a fluid-communicating manner. A compressed air system (60) for providing compressed air (70) has such an air-drying device (10).
US10046269B2	Acidic gas absorbing agent, method for removing acidic gas and apparatus for removing acidic gas There are provided an acidic gas absorbing agent that is large in recovery amount of an acidic gas. The acidic gas absorbing agent comprising an amine compound represented by general formula (1), and an acidic gas removing method and an acidic gas removing apparatus using the absorbing agent: wherein R1 represents a cycloalkyl group having 3 to 6 carbon atoms; R2 represents an alkyl group having 1 to 3 carbon atoms or a hydrogen atom; R3 and R4 each independently represent an alkyl group having 1 to 3 carbon atoms or a hydrogen atom; and R5 represents an alkyl group having 1 to 3 carbon atoms.
US10046265B2	Oxygen separation system and method of generating a flow of oxygen enriched gas The present invention refers to an oxygen separation system (10), comprising a support (12) for accommodating a plurality of autonomous oxygen separation units (14), wherein the support (12) comprises a plurality of fastening positions having fastening means for receiving an oxygen separation unit (14); and a plurality of autonomous oxygen separation units (14) being attached to said support (12), each oxygen separation unit (14) comprising at least one oxygen separation device (28) with an oxygen separation sorbent (30) being capable of separating oxygen from an oxygen comprising gas by sorbing at least one component of the oxygen comprising gas apart from oxygen, and a gas conveying device (44) for guiding a flow of oxygen comprising gas through the oxygen separation device (28). Such an oxygen separation system (10) may have significant improvements against the systems of the prior art, particularly referring to space, weight, energy consumption, variability, flexibility and maintenance behavior. The invention further relates to a method of generating a flow of oxygen enriched gas.
US10046262B2	Method and system to excavate and remove underground noxious vapors A system to excavate and remove underground noxious vapors includes a suction wand in fluid communication with a debris tank. A collar is fitted around the suction wand and is configured to seal noxious vapors within a hole around the suction wand. A primary valve is used to control whether the suction wand is being used to excavate material to send to the debris tank, or whether the suction wand is being used to remove noxious vapors from the hole to send to a filtration unit. A monitor is configured to detect explosive concentrates in the noxious vapors to determine whether the explosive concentrates exceed an acceptable level. In addition, the system is configured to dilute and filter the noxious vapors before discharging to the atmosphere.
US10046261B2	Filtration system and method Described are multi-stage drum filtration systems including a primary rotary drum filter stage, at least one passive filter stage, and a main fan configured to create a vacuum on an inlet side of the primary rotary drum filter stage. The multi-stage drum filtration system may also include a HEPA filter stage. A controller may be configured to control a speed of the main fan to maintain an inlet vacuum to the primary rotary drum filter stage that corresponds to an inlet vacuum set point input.
US10046258B2	Device for locking a filter in a conduit A device for locking a filter in a conduit for use in heat exchangers is described. The device includes: a main body apt to be associated with the filter and made in two parts, and three locking arms, which branch off from the main body and have each a first longitudinal end which can be tightened within the main body and a second longitudinal end which abuts on the conduit to block the filter. The locking arms are movable with respect to the main body so as to assume a first configuration of minimal encumbrance, in which the insertion of the device in the conduit is allowed, and a second locking configuration, in which the second longitudinal ends are abutted on the walls of the duct. The device allows a removable locking of the filter in the conduit.
US10046256B2	Spin-on filter with external threads and methods A filter arrangement for threadably securing to a filter head includes a housing having a surrounding wall defining an interior volume, an open mouth providing access to the interior volume and an end opposite of the open mouth. The surrounding wall has an exterior and an interior. A filter media construction is operably held within the interior volume. A sleeve, distinct from the housing, is secured to the exterior of the surrounding wall adjacent to the housing mouth and extending partially along the surrounding wall. The sleeve has an exterior and an interior. The exterior of the sleeve defines mounting threads constructed and arranged to removably mount with the filter head, when the filter arrangement is secured to the filter head. The interior of the sleeve is against the exterior of the surrounding wall. A first seal member is oriented against the sleeve to create a seal with a filter head, when the filter arrangement is secured to the filter head. A filter assembly includes a filter arrangement and a filter head. The filter arrangement is removably secured to the filter head by a threaded connection between the sleeve and the filter head. A system includes an engine utilizing a liquid and a filter assembly in fluid communication with the engine to filter the liquid. Methods of making filter arrangements include utilizing structures characterized above.
US10046254B2	Endcap bypass plug, endcap assembly and filter assembly An endcap bypass plug includes a body and a plurality of leg members. The body includes an upper surface, a lower surface, and an outer side surface joining the upper and lower surfaces. The plurality of leg members are connected to and extend away from the upper surface of the body. Adjacent leg members of the plurality of leg members are spaced apart by a distance to form a plurality of radial passages defining a plurality of radial fluid-flow paths. Each leg member includes a head portion having an upper surface. The head portion includes a nose portion extending radially outwardly from the head portion and including a ramp surface and a lower surface. The ramp surface of the nose portion is connected to the upper surface to define an upper edge. The ramp surface is connected to the lower surface of the nose portion to define a lower edge.
US10046253B2	Filtration device A filtration device including: a casing 1 having a fluid inlet 6, a fluid outlet 7, a raw fluid chamber 8, and a filtered-fluid chamber 9; a box-shaped or tube-shaped filter element 3 (3a, 3b) having a filter medium 31 removably installed inside the casing 1, allowing the fluid to pass through from inside to outside to filter the fluid, and having a backwashing mechanism inside thereof; and a backwash fluid discharge pipe 4 which discharges backwash fluid to the outside, wherein the backwashing mechanism has a fixed pipe 33 fixed to the inside of the filter element, a movable pipe 34 movably fitted to the outside of the fixed pipe, and a backwash head 35 attached to the movable pipe to backwash the filter medium, wherein the fixed pipe and the movable pipe movably guide the backwash head and form a discharge passage for backwash fluid.
US10046252B2	Sand separator interface detection A sand separator is provided that includes a separation chamber and a drain. The sand separator comprises a meter in fluid communication with an interior of the separation chamber, wherein the meter is configured to detect a liquid/solid interface. Meter electronics in electrical communication with the meter are configured to receive a signal from the meter indicating the liquid/solid interface.
US10046244B2	Method and system for operating and participating in fantasy leagues A system and computer-implemented method for operating a fantasy league including: fantasy player information including performance history of one or more real-world athletes selected as fantasy players is stored. Sponsorship information associated with the fantasy player is stored on at least one of an individual or team basis. An operational request from a fantasy client device is received. An association between the operational request and the fantasy player is determined. An operational result is determined. At least one item of sponsorship information is associated with the operational result. The operational result and the sponsorship information are transmitted. An alert window is displayed at the fantasy client device including the sponsorship information.
US10046240B2	Social networking data augmented gaming kiosk In particular embodiments, a method includes receiving a message in response to detection of a token by a presence reader; transmitting a request to access an account associated with an external network in response to receiving the message; establishing access to the account in response to authentication of the request by a server in the external network; and debiting value from a funding source associated with the account after establishing access to the account.
US10046239B2	Monitoring advertisement impressions A targeted in-game advertising system is provided where advertising content may be delivered to a video game network environment. Advertisements may be delivered through the tagging of advertising assets in the video game environment according to one or more characteristics including user geographical location, personal preferences, a personal profile, video game preferences or video game genre. Methodologies for tracking advertising impressions are also provided based on monitoring the video game environment to determine the quality of impression to which the user is exposed in the video game environment.
US10046238B2	Gaming system Methods and systems for providing gaming services are provided. One system includes a operating system for executing a first game logic that is configured to define a game environment in response to game commands for a first user as well as for executing a second instance of game logic for the game environment for the game. The system also includes virtual drivers associated with the operating system, a non-virtual driver associated with a hardware graphics processing unit (GPU), and a shared memory. The GPU is configured to render a first video stream for the first game logic and a second video stream for the second game logic. One or more dynamic encoding pipelines (DEPs) are used for encoding video frames of the second video stream for transmission to a client device of the second user. The gaming system also includes an I/O device for communicating the first video stream to a display of the first user and for communicating the second video stream to the client device.
US10046232B2	Augmented reality for table games A method includes acquiring media content of a wagering game table at a wagering game establishment with a camera of a mobile device. A location of the mobile device is determined when the media content is acquired. A direction that a lens of the camera is facing when the media content is acquired is determined. The wagering game table is identified based on the location and the direction. Overlay imagery derived from wagering game activity of the wagering game table is downloaded into the mobile device from a server. The overlay imagery is composited onto the media content to create a composited media content. The composited media content is displayed on a display of the mobile device.
US10046229B2	Smart device An Internet of Thing (IoT) device includes a body with a processor, a camera and a wireless transceiver coupled to the processor.
US10046226B2	Personal signal device to be used for water sports A personal signal device can be worn on an arm of a water sport participant and includes a signal flag that is stowed in a pouch of the device and can be removed from the pouch and manually waved by the water sport participant when the water sport participant is in the water.
US10046220B2	Swing analysis device, non-transitory computer-readable storage medium storing program for analyzing swing, and swing analysis system A swing analysis device for analyzing a swing of a ball hitting tool includes: an information input unit configured to receive input of acceleration information and angular velocity information detected by a sensor attached to the ball hitting tool; a posture calculation unit configured to calculate posture information of the ball hitting tool in the swing by applying a predetermined filter to the acceleration information and the angular velocity information; a correction unit configured to correct the posture information of the ball hitting tool in the swing based on the posture information of the ball hitting tool at a first time in the swing; and a swing information calculation unit configured to calculate a swing trajectory of the ball hitting tool based on the acceleration information and the posture information of the ball hitting tool corrected by the correction unit.
US10046217B2	System and method for weighting a golf club A system and method for weighting a golf club. The system is configured to adjust the overall club weight and the weight balance of a golf club.
US10046210B1	Golf ball incorporating pair of thin hemispherical cups having targeted configuration/geometry and being compression molded about large, soft subassembly/core Golf ball having CoR of at least 0.700 and comprising: a substantially spherical subassembly having diameter of 1.3 inches or greater and compression of from about 15-60; and a thin outer layer having a compression molded thickness of about 0.015-0.055 inches and consisting of first and second hemispherical cups consisting of a polymer composition having a melt flow index at 190° C. under a 2.16-kg load of from about 0.8 g/10 min. to about 4 g/10 min. and having a cup thickness ratio of from about 1.10 to 1.70 as well as an inner surface that is sized, shaped and contoured to receive and conformally and adhesively mate onto and about the subassembly during compression molding such that the subassembly in the finished golf ball is substantially spherical and disposed concentrically within the thin outer layer. Also, the novel hemispherical cups and the method of making the golf ball.
US10046207B2	Multi-piece solid golf ball In a multi-piece solid golf ball having a core, a cover and an intermediate layer therebetween, the core, an intermediate layer-encased sphere and the ball have surface hardnesses which satisfy a specific relationship, and the intermediate layer and the cover have thicknesses which satisfy a specific relationship. Also, the core has a hardness profile in which the hardnesses at the core surface, core center, a position 5 mm from the core center, and a position midway between the surface and center of the core satisfy specific relationships. This golf ball, when used by mid- and high-level amateurs, enables the golfer to maintain an adequate distance on shots with a driver and achieve a good distance on iron shots, has a good spin performance on approach shots and has a good feel on impact. In addition, the ball has an excellent scuff resistance when struck with a grooved wedge.
US10046204B2	Golf ball An object of the present invention is to provide a golf ball showing an increased spin rate on approach shots under a wet condition while maintaining a spin rate on approach shots under a dry condition. The present invention provides a golf ball comprising a golf ball body and a paint film formed on a surface of the golf ball body, wherein the paint film has a multi-layered construction composed of two or more layers, and a difference (Mout−Min) between a 10% elastic modulus (Mout) of an outermost layer of the paint film and a 10% elastic modulus (Min) of an innermost layer of the paint film is 25 kgf/cm2 or more.
US10046201B2	Electronic apparatus and program An electronic apparatus includes: a control unit that, in an interval training in which a high intensity exercise and a low intensity exercise are repeated, calculates one or both of a high intensity exercise time for performing the high intensity exercise and a low intensity exercise time for performing the low intensity exercise based on input time information.
US10046200B2	Height target scoring device The present invention provides a height target exercise scoring device comprising a pad adapted to absorb repeated impacts, the pad including a front surface, a rear surface, and one or more impact sensors positioned beneath the front surface. The target height exercise scoring device also includes a housing coupled to the pad including a control system. The control system includes an interface for inputing a target height parameter, and a processor coupled to the one or more impact sensors configured to determine whether an impact registered by the array of impact sensors occurs on the pad at or above the input target height. The a control system can wirelessly communicate with a mobile device configured to execute a mobile application for configuring the settings of the scoring device, and to send data to, and receive data from, the scoring device.
US10046198B1	Wheel exercising device A wheel exercising device includes a shank, two handgrips, two wheels, and two caps. The shank has a first threaded section and a second threaded section having different screwing directions. Each of the two handgrips is formed with an internal threaded section screwed onto the first threaded section and the second threaded section of the shank. At least one elastic member is connected between the two handgrips. Each of the two wheels is mounted on the shank. Each of the two caps is mounted on the shank and rests on one of the two wheels. When the two wheels are rotated forward and backward, the two handgrips are moved inward and outward synchronously along the first threaded section and the second threaded section of the shank.
US10046196B2	Pedal path of a stepping machine A vertical stepping machine includes a frame, a crank wheel connected to the frame, a crank wheel connected to the frame, a pedal beam having a first end and a second end, wherein the first end is in mechanical communication with the crank wheel, a pedal connected to the second end of the pedal beam, a linkage assembly connected to the frame and to the pedal beam, an arm support rotatably connected to the frame, an arm linkage connecting the arm support to the linkage assembly, and a rotary resistance mechanism positioned above the crank wheel when the vertical stepping machine is in an upright orientation. The pedal beam moves in an elliptical path when the crank wheel rotates and the elliptical path has a vertical major axis and a horizontal minor axis when the vertical stepping machine is in an upright position.
US10046192B2	Method and apparatus for extremity rehabilitation A lower extremity mobilizer for use in rehabilitation is provided. A seat is slidably maintained upon a base, with a foot support brace being provided at an end of the base to receive the foot of a leg provided for arthrokinematic treatment. A cord and pulley system is provided between the seat and the end of the base. In use, a patient is seated with a foot received by the foot support brace. The patient provides arthrokinematic motion to his leg by pulling himself and the seat toward the end of the device having the foot support brace. The procedure is undertaken in a closed chain motion, with the foot constantly engaging the foot support brace, and is done so as a rate, timing and extent under the control of the patient.
US10046185B2	Fire and smoke compositions and the processes of making them A method for fire and smoke prevention, suppression or extinction using a composition having sodium polyacrylate and distilled water, wherein the ratio of sodium polyacrylate to distilled water is about 1 to 200, having the step of placing the composition in the path of the fire or smoke.
US10046184B2	Aircraft crew member protective breathing apparatus A self-contained breathing device for use in fighting fires comprising a hood for covering a wearer's head, a membrane for sealing the hood to create a breathing chamber inside the hood, and a source of oxygen disposed inside the hood. The source of oxygen is connected to the user by a conduit inside of the hood, and another conduit directs user-exhaled carbon dioxide to the source of oxygen. The breathing device includes a visual indicator inside of the hood that reacts to the presence of a gas within the hood and provides visual feedback to the user based on a quantity of the gas present in the hood.
US10046182B2	Methods for face and neck lifts Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue on a face and/or neck are described.
US10046176B2	Radiotherapy system provided with a program for the calculation of the intensity of an electrons beam A system for radiotherapy includes an accelerator of an electron beam, an imaging apparatus, a control unit and a radiation dose sensor connected to the control unit equipped with a program configured to execute the steps: setting a first intensity of the electron beam, according to a predefined image of a target zone, the intensity to be emitted in a first radiation; operating said accelerator to emit the first radiation being a fraction of the first intensity; detecting a real intensity during the first radiation by the radiation dose sensor; acquiring an image of the zone; calculating an intermediate intensity according to the image acquired in the step and according to the real intensity; and comparing the first intensity with the intermediate intensity to calculate a final beam intensity for a subsequent second radiation.
US10046174B2	System for electrically stimulating target neuronal cells of a living animal in vivo In one example, a system electrically stimulates target cells of a living animal using an elongated structure, a modulation circuit and a light pathway such as provided by an optical fiber arrangement. The elongated structure is for insertion into a narrow passageway in the animal such that an end of the elongated structure is sufficiently near the target cells to deliver stimulation thereto. The modulation circuit is for modulating the target cells while the elongated structure is in the narrow passageway, where the modulation circuit is adapted to deliver viral vectors through the elongated structure for expressing light responsive proteins in the target cells. The light pathway is used for stimulating the target cells by delivering light to the light-responsive proteins in the target cells.
US10046169B2	Automatic defibrillation operation for a defibrillator A defibrillator (20) employs a ECG monitor (23), a shock source (24) and a controller (25). In operation, the controller synchronizes a ECG analysis window (EAW) to a shock activation of the defibrillator, and analyzes a ECG waveform (30) of a heart (11) of a patient (10) as monitored by the ECG monitor within the ECG analysis window for detecting the patient experiencing an organized heartbeat condition or an unorganized heartbeat condition. The controller further controls a delivery by the shock source of a synchronized defibrillation shock to the heart of the patient in response to a detection within the ECG analysis window by the controller of the patient experiencing the organized heartbeat condition, or controls a delivery by the shock source of an unsynchronized defibrillation shock to the heart of the patient in response to a detection by the controller within the ECG analysis window of the patient experiencing one of the unorganized heartbeat condition or an undetected organized heartbeat condition.
US10046159B2	Delivery assembly for percutaneously delivering and deploying an electrode array at a target location, the assembly including a steerable core around which the array is wrapped An electrode array and a delivery assembly. The array is wrapped around a flexible core part of the delivery assembly. A sheath, also part of the delivery assembly, is disposed over the array and core. Steering cables extend through the core. Once the delivery assembly-encased array is inserted in the body, the combination is advanced to the tissue over which the array is to be deployed. By pulling on the steering cables the array and assembly are steered into position. Once the array is in position, the sheath is retracted, the array deploys over the target tissue.
US10046157B2	Connector A connector of the present invention includes a housing and a valve, wherein the housing has a flow path and a pipe connecting port, and the valve is formed of an elastic material and is adapted to block the pipe connecting port. The valve has a substantially columnar deformable portion. The deformable portion has a top surface exposed from the pipe connecting port, a bottom surface opposite to the top surface, and a slit that extends from the top surface to the bottom surface. When the top surface is pressed by the pipe, the deformable portion of the valve will be displaced toward the flow path while elastically deforming, so that inner surfaces that define the slit will face the flow path, and the top surface will form an opening that communicates with the flow path.
US10046155B2	Luer connector A luer lock connector is disclosed. The luer lock connector includes a connector body having a distal end, a proximal end, and a gripping portion between the distal end and the proximal end. A substantially flexible material is disposed on at least the outer surface of the gripping portion of the connector body. An intravenous line is coupled to the distal end of the connector body. A luer connector fitting is disposed on the proximal end of the body, the luer connector having an outer diameter less than a maximum exterior thickness of the gripping portion of the connector body.
US10046154B2	Medical connector with closeable luer connector Some embodiments relate to a luer connector comprising a housing having a hollow bore therethrough, a first end, and a second end, a male luer tip supported by the housing configured to rotate with respect to the housing, the luer tip having a first open end and a passageway through the luer tip in fluid communication with the first open end, and a substantially rigid internal member extending into the passageway of the luer tip toward the first open end of the luer tip. In some embodiments, at least one of the luer tip and the internal member can be axially moveable between a first closed position and a second open position relative to the other of the luer tip and the internal member. Further, the luer tip and the internal member can cooperate such that rotation of the luer tip in a first direction relative to the housing increases an axial displacement between the first open end of the luer tip and an end portion of the internal member.
US10046152B2	Operation tool for fluid injector using multi-microneedle device An operation tool for a fluid injector includes a selective movement mechanism which moves the fluid injector between a first protruding position and a second protruding position in a housing of an outer cylinder. When the fluid injector is at the first protruding position, microneedles of a multi-microneedle device are protruded out to a first distance from the first open end. When the fluid injector is at the second protruding position to discharge a fluid via the microneedles, the microneedles are protruded out to a second distance from the first open end, which is shorter than the first distance. The selective movement mechanism includes a rotational-linear movement conversion mechanism which moves the fluid injector between the first and second protruding positions along a longitudinal center line of the outer cylinder based on a direction and an amount of rotation of the outer cylinder relative to the fluid injector.
US10046149B2	Dilation system and method A dilation system and method for accessing a surgical target site to perform surgical procedures. In one version, the dilation system includes a dilation assembly and an actuating mechanism. The dilation assembly comprises plurality of dilator segments. The actuating mechanism is operably associated with the dilator segments so as to cause the dilator segments to move from a collapsed state to an expanded state.
US10046146B2	Cutting balloon catheter A medical balloon catheter including a catheter shaft and an inflatable balloon secured to a distal portion of the catheter shaft. One or more cutting blades are secured to the inflatable balloon by a first polymeric adhesive material forming a mounting pad encasing a base portion of the cutting blade therein, and a second polymeric adhesive material adhesively bonding the mounting pad to a surface of the balloon. The first polymeric adhesive material has a first ductility and the second polymeric adhesive material has a second ductility greater than the first ductility.
US10046140B2	Devices, systems, and methods for controlling active drive systems The present application is related to devices, systems, and methods for controlling active drive systems. In one embodiment, the drive system may include a first surface and a second surface for engaging an elongate member. The first and second surfaces may be attached to a drive mechanism to move the elongate member. The first surface may be slidable relative to the drive mechanism and may have a clearance between the drive mechanism and an end of the first surface during movement of the elongate member in a non-slip condition. A sensor may be associated with the first surface and may be configured to detect movement of the first surface in a slip condition.
US10046139B2	Reconfirmation of ECG-assisted catheter tip placement A catheter includes a proximal portion designed for residing externally of a patient vasculature and a distal portion having a distal tip designed for placement in a desired position within the patient vasculature. A storage component is embedded in a portion of the catheter, the storage component including a radio-frequency identification (RFID) chip. The RFID chip includes non-volatile memory that is programmable by a RFID encoder. The storage component includes data related to the placement of the distal tip of the catheter in the desired position within the patient vasculature.
US10046138B2	Atraumatic ureteral access sheath Ureteral access sheaths can have a nonuniform axial-stiffness. A nonuniform axial-stiffness ureteral access sheath can have an inner liner defining a longitudinally extending and generally uniform bore. A non-uniform axial-stiffness outer jacket can define a longitudinally tapered outer surface, and a reinforcement layer can be encapsulated between the inner liner and the non-uniform axial-stiffness outer jacket. The reinforcement layer can have a non-uniform axial-stiffness. For example, a proximal portion of the reinforcement layer can be thicker than a distal portion of the reinforcement layer. A coil of wire can be included in the reinforcement layer, and a diameter of the wire in a proximal portion of the reinforcement layer can be larger than a diameter of the wire in a distal portion of the reinforcement layer. In some instances, the diameter of the wire tapers from the proximal portion to the distal portion.
US10046136B2	Automatic humidity control in a pressure support system A method of automatically controlling the humidity of a gas stream of a pressure support system (50) during use of the system is provided. The method includes receiving a first humidification level, and controlling operation of a humidifier (68) based on the first humidification level and at least one of: (i) one or more environmental parameters relating to environmental conditions around the pressure support system, (ii) one or more gas stream parameters relating to a gas stream output by the pressure support system to a patient circuit (56, 58), (iii) one or more respiratory demand parameters of a user of the pressure support system, and (iv) one or more operating parameters of the pressure support system that effect a flow rate that is generated by a pressure generating system (52, 60) of the pressure support system.
US10046134B2	Pressure swing adsorption oxygen generator A pressure swing adsorption oxygen generator to separate oxygen from air for use with a pressure source generating a high pressure and a low pressure. The pressure swing adsorption oxygen generator includes an adsorption bed having a bed of nitrogen absorbent material; and a multi-position rotary valve for controlling pressure swing adsorption of the adsorption bed, and being couplable to the pressure source for fluid communication therewith and in fluid communication with the adsorption bed. The rotary valve includes a cam having first and second rotary positions, in the first rotary position of the cam the rotary valve communicating high pressure generated by the pressure source to the adsorption bed and in the second rotary position of the cam the rotary valve communicating low pressure generated by the pressure source to the adsorption bed.
US10046133B2	Methods, systems and devices for non-invasive open ventilation for providing ventilation support A system for providing ventilation support to a patient may include a ventilator, a control unit, a gas delivery circuit with a proximal end in fluid communication with the ventilator and a distal end in fluid communication with a nasal interface, and a nasal interface. The nasal interface may include at least one jet nozzle at the distal end of the gas delivery circuit; and at least one spontaneous respiration sensor for detecting respiration in communication with the control unit. The system may be open to ambient. The control unit may receive signals from the at least one spontaneous respiration sensor and determine gas delivery requirements. The ventilator may deliver gas at a velocity to entrain ambient air and increase lung volume or lung pressure above spontaneously breathing levels to assist in work of breathing, and deliver ventilation gas in a cyclical delivery pattern synchronized with a spontaneous breathing pattern.
US10046131B2	Patient interface with cushion for red mark prevention A patient interface and a patient interface system comprise a responsive material and a method for preventing the formation of red marks due to wearing a patient interface that is pressing against the skin of a patient for a longer time and/or for reducing air leakages of the patient interface that may result from an unintended shift of the patient interface on the patient's face. The responsive material is configured for alternating the pressure exerted by the cushion element on the patient and/or the area on the patient where the pressure is exerted by the cushion element in response to a physical quantity acting on the responsive material. The formation of red marks and of air leakages can be reduced or even avoided by means of the responsive material.
US10046130B2	Airway-tube holder An air-way tube holder includes a face plate having a v-shaped tube-receiving surface that aligns with one side of an opening through the face plate, and a holding block, which is disposed near a second side of the opening. The holding block receives a thumb screw and an engagement arm, the latter including a clamping head, which directly opposes the tube-receiving surface. The thumb screw is adapted to move the clamping head toward the tube-receiving surface to immobilize an airway tube therebetween, either by sliding the thumb screw (gross adjustment) or turning the thumb screw (fine adjustment). The thumb screw/clamping head is releasable by actuating a quick-release mechanism.
US10046127B2	Pressure support ventilation of patients A methodology and apparatus for determining ventilator settings including an end expiratory pressure setting, pressure swing, resistive unloading and target ventilation for delivering ventilatory support based upon generalized patient ventilation characteristics and/or disease classifications. An apparatus may be programmed with the instructions to accomplish the methodology interactively by prompting the user/physician during setup and calculating settings based upon measurements or input responses. Pre-assigned values associated with ventilation characteristics or disease classifications may be combined with a base pressure value or measured values to provide patient customized settings or adjustments to determine pressure levels for the delivery of ventilatory support.
US10046126B2	Apparatus and method for delivering fluids and/or gases to the lungs An apparatus and method for providing heat exchange in the lungs of the mammal during partial liquid ventilation are provided. The apparatus and method can control delivery and removal of partial liquid ventilation to the lungs of a mammal by responding to pressure change in the lungs to minimize danger of causing barotrauma to the patient.
US10046124B2	Inhaler An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
US10046120B2	Device for detecting moisture for an arrangement for monitoring an access to a patient A device for detecting moisture for an arrangement for monitoring an access to a patient for a system by which, via a flexible line, a liquid is fed to a patient and/or a liquid is fed out from the patient, and in particular for monitoring the vascular access in extra-corporeal blood treatment and particularly for monitoring a central venous catheter for acute dialysis includes at least a portion which can be deformed into a sleeve and placed around the circumference of the flexible line or of a connecting system. The portion in sleeve form has fastening means for fixing it in place in the position in which it surrounds the flexible line or the connecting system. The portion in sleeve form allows the device to be fastened quickly and securely to a flexible line or a connecting system.
US10046118B2	Bearing for a piston rod body for a drug delivery device, a piston rod arrangement and a piston rod body The present disclosure concerns a bearing for a piston rod body for a drug delivery device. The bearing has an axis and comprises a first and a second surface which are spaced apart in the direction of the axis and a third surface, wherein the third surface connects the first and the second surface, wherein an opening is provided in each of the first and the third surface, and wherein the opening in the first surface is connected to the opening in the third surface. Further, the present disclosure concerns a piston rod body and a piston rod arrangement comprising said bearing and the piston rod body.
US10046115B2	Drive control mechanisms and automatic injectors for injectable cartridges An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor. The novel incorporation of the drive control mechanisms into the automatic injectors of the present invention enables a single motor and transmission assembly to drive the function of multiple components, which may include the steps of: preparation and alignment of a cartridge for injection, removal of a safety cap or needle shield, needle injection, drug dose delivery, and syringe and/or needle retraction. Methods of manufacture and methods of use are also disclosed.
US10046114B1	Control of a peripheral device with a bandage-type analyte sensor An example system includes a flexible substrate configured to be mounted to a skin surface. The system includes a sensor probe that has a first end attached to the flexible substrate and a second end configured to extend beneath the skin surface to contact interstitial fluid. A sensor is configured to measure a physiological property and is disposed at the second end of the sensor probe. A transmitter is attached to the flexible substrate and is configured to provide information related to sensor measurements to a controller. The controller is configured to a drug delivery rate based on the information.
US10046113B2	Systems and methods for determining insulin therapy for a patient In example methods and systems described, insulin therapy for a patient can be determined. At least one of a short-acting subcutaneous insulin dosage recommendation, a correction subcutaneous insulin dosage recommendation, an intravenous insulin dosage recommendation, a recommended amount of carbohydrates to be administered to the patient, or combinations thereof, can be determined. In addition, information indicating a confirmation of a nutrition intake for the patient, and a long-acting insulin-on-board for the patient can be received, and based on this information, a required long-acting subcutaneous or intravenous insulin dosage for the patient can be determined. The short-acting subcutaneous or intravenous insulin dosage recommendation can be adjusted based, at least in part, on a difference between the long-acting insulin-on-board and the required long-acting subcutaneous or intravenous insulin dosage.
US10046111B2	Needle insertion and retraction arrangment with manually triggered, spring-loaded drive mechanism Disclosed is a needle insertion arrangement (1) with a drive mechanism (9) comprising: a belt (15) frictionally engaging a first roller (10) and a needle retainer (7) with an injection needle (2) fixed to the belt, the first roller being rotatably arranged about an axis (A), a second roller (11) also rotatably arranged about the axis (A), a first spring (13) rotatably biasing the first roller against the second roller, a second spring (14) rotatably biasing the second roller against an arrester (12), the first and the second roller being connected via an internal protrusion (10.2) and arcuate slot (11.2), the two springs (13, 14) biasing the rollers (10, 11) from respective first to respective second angular positions (AP11, AP12, AP21, AP22), and a trigger mechanism (17,20) releasably locking the first and second rollers (10, 11) such that upon pivoting the trigger button (20) in one direction, the first roller drives the belt in one direction to linearly transport the needle retainer towards an extended position, and upon pivoting the trigger button in the other direction, the first roller drives the belt back to retract the needle retainer.
US10046110B2	Lock for drug injection device A drug injection device comprises a main body case, a drug syringe mounting component, a piston, a drive mechanism, a controller, and means for locking the lid during operation of the drug injection device. The main body case has a lid and a base and an injection needle let-in/let-out opening. The drug syringe mounting component is provided inside the main body case, and allows a (filled) drug syringe to be mounted therein. The piston is movable with respect to the drug syringe mounting component. The drive mechanism drives the drug syringe mounting component and the piston. The controller is electrically connected to the drive mechanism. The means for locking the lid during operation of the drug injection device is activated and deactivated by movement of the drug syringe mounting component when the lid is closed.
US10046108B2	Compact intravenous pump and medication container holder A compact intravenous pump and medication container holder. The present invention has a substantially flat base having a peripheral edge with one or more sidewalls placed along the edge. The sidewalls are positioned substantially perpendicular to the base, forming an interior adapted to removably secure an intravenous pump. An arm is placed substantially perpendicular to the base on one side thereon and extends upward therefrom. The arm has a first end secured to the base, and a second end having a fastener adapted to support a medication container. A strap is affixed to one side of the base and is adapted to secure an intravenous pump to the base.
US10046106B2	Bladder syringe fluid delivery system A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.
US10046098B2	Prevention of aortic valve fusion Materials and methods related to blood pump systems are described. These can be used in patients to, for example, monitor arterial pressure, measure blood flow, maintain left ventricular pressure within a particular range, avoid left ventricular collapse, prevent fusion of the aortic valve in a subject having a blood pump, and provide a means to wean a patient from a blood pump.
US10046090B2	Processed bone particle compositions and related methods Bone particle compositions and kits are provided that include a biologically-resorbable cement and a plurality of processed bone particles. A first portion of the processed bone particles in the compositions have a shape configured to interconnect with one another, while a second portion of the processed bone particles having an irregular shape. Methods for treating a bone defect are also provided wherein an effective amount of the bone particle compositions are administered to a site of a bone defect in a subject.
US10046082B2	Collagen sponge containing a drug for promoting fracture healing and method for preparing the same Provided are a collagen sponge containing a drug for promoting fracture healing and a method for preparing the same, the method comprises the steps of: 1) adding bisphosphonate containing phosphonate radical in an equivalent dosage of 70 to 140 mg and/or strontium salt in a dosage of 100 to 800 mg into 1 kg of the enzymolysis solution of collagen; 2) adding a crosslinking agent into the solution, the crosslinking agent being added in a proportion where 40 to 60 U of crosslinking agent is added per gram of enzymolysis solution; 3) stirring the mixed solution in step 2) uniformly, then putting it into a stainless steel tray, and placing the tray in a vacuum lyophilizer for lyophilizing for 10 to 16 hours so that it is lyophilized into a sponge-like shape; and 4) allowing the collagen sponge in step 3) to be cut, packaged and sealed, and sterilized by irradiation with cobalt 60.
US10046080B2	Absorbent articles with multilayer laminates An absorbent article comprising a topsheet, an outer cover, at least one chassis component, and an absorbent core disposed between the topsheet and outer cover, wherein at least one of the outer cover or chassis component comprises a laminate comprising at least one nonwoven layer and at least one multilayer film, wherein the multilayer film has at least four layers and comprises at least one inner layer comprising one or more elastomeric components, at least one outer layer comprising a plastoelastic component, and at least one additional polymeric layer that is disposed next to an inner layer.
US10046075B2	Device for transmitting and projecting greater photonic energy A device for transmitting and projecting greater photonic energy. The device includes at least one photonic source for generating and emitting photonic energy in a wavelength or in a range of wavelengths of visible light. The device also includes a lens formed of a fluoropolymer material wherein the at least one photonic source is sealed within an interior and underneath an outer surface of the fluoropolymer material so as to be surrounded by the fluoropolymer material. The at least one photonic source is coupled with the lens such that the photonic energy emitting from the at least one photonic source transmits through and projects beyond the fluoropolymer material. The lens propagates photons in an omnidirectional pattern simultaneously throughout the entirety of the lens. The joining of the at least one photonic source and the fluoropolymer material comprises all components for generating and emitting photonic energy when the photonic source is activated, such that it is an operable source. The cumulative photonic energy generated and emitted by the at least one photonic source is greater than the photonic energy emitted by the photonic source in the absence of the fluoropolymer material.
US10046074B2	Fluid sterilizer and associated connecting device A sterilizer may include: a first pipe having an inner wall with a light reflecting property; a second pipe disposed in the first pipe so as to pass fluid therethrough and formed of a light transmitting material; and a plurality of UV LEDs arranged on the inner wall of the first pipe and configured to irradiate sterilization UV light onto the fluid.
US10046073B2	Portable UV devices, systems and methods of use and manufacturing Provided herein are portable ultraviolet (UV) devices, systems, and methods of use and manufacturing same. Methods of use include methods for UV disinfection and sterilization, more specifically, methods for UV disinfection and sterilization of a container, a room, a space or a defined environment. The portable UV devices, systems and methods are particularly useful for the UV disinfection and sterilization of a container, a room, a space or defined environment used in the food, beverage and dairy industry and in the process of fermentation for an alcoholic beverage. Provided are also portable UV devices, systems, and methods for inhibiting the growth of one or more species of microorganisms present in a container, a room, a space or a defined environment, preferably for inhibiting the growth of one or more species of microorganisms present on an interior surface of a container, a room, a space or a defined environment.
US10046068B2	Saccharide conjugates This invention relates to compounds comprising a saccharide conjugated to an imaging agent or a reporter group, compositions comprising them and methods of using them. Specifically BLM-disaccharide and BLM-monosaccharide conjugates containing different linker groups and an imaging agent or a reporter group are provided for the targeting and imaging of tumors.
US10046061B2	Site-specific insulin conjugate Provided are an insulin conjugate having improved insulin receptor binding affinity and increased activity, in which a non-peptidyl polymer and an immunoglobulin Fc region are site-specifically linked to an amino acid residue of the insulin beta chain excluding the N-terminus thereof via a covalent bond, a long-acting formulation including the same, and a preparation method thereof. The insulin conjugate of the present invention is used to provide an insulin formulation which exhibits a remarkably increased in vivo activity of the peptide.
US10046060B2	Co-administration of an agent linked to an internalization peptide with an anti-inflammatory The invention provides methods of delivering pharmacologic agents linked to an internalization peptide, in which an inflammatory response inducible by the internalization peptide is inhibited by co-administration of an anti-inflammatory or by linking the internalization peptide to biotin or similar molecule. Such methods are premised in part on the results described in the examples whereby administration of a pharmacological agent linked to tat at high dosages is closely followed by an inflammatory response, which includes mast cell degranulation, histamine release and the typical sequelae of histamine release, such as redness, heat, swelling, and hypotension.
US10046057B2	Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy There are disclosed compositions and methods to render nucleic acids resistant to nuclease digestion while maintaining sequence selective hybridization competency. The approach relies on utilizing nucleic acids as the polar head group of a nucleic acid-polymer amphiphile in order to assemble well-defined, discrete micellar nanoparticles. Dense packing of nucleic acid in the micelle corona allows for hybridization of complementary oligonucleotides while prohibiting enzymatic degradation.
US10046055B2	Bone targeted therapeutics and methods of making and using the same The present invention provides novel bisphosphonate conjugates, pharmaceutical compositions comprising bisphosphonate conjugates and methods of using such analogs in the treatment of bone cancer, bone-related diseases, bone infection, bone inflammation, and diseases of the soft tissues surrounding bones.
US10046049B2	Engineered cells expressing multiple immunomodulators and uses thereof This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally expressing interleukin-12 (IL-12) and one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals.
US10046044B2	Prevention of pertussis using adenylate cyclase deficient Bordetella strains A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
US10046041B2	Methods and compositions for suppressing virulence of methicillin resistant Staphylococcus aureus The present invention is directed to methods of suppressing the virulence of one or more virulence antigenic factors of methicillin resistant Staphylococcus aureus (MRSA). Aspects of the invention include administering of an expression vector alone or in conjunction with a fusion protein. The expression vector has a transcription unit encoding a fusion protein composed of a virulence antigenic factor of MRSA attached through a linker to the aminoterminal end of the ecd CD40 ligand. The fusion protein is composed of a virulence antigenic factor of MRSA and CD40 ligand and has the ability to generate antibodies which prevents host cell infection by suppressing virulence functions of MRSA.
US10046032B2	Use of insulin for promoting gastric emptying The present disclosure provides means and methods for promoting gastric emptying. In particular, the present disclosure provides the use of insulin or a composition comprising same for promoting gastric emptying and for treating gastric disorders, particularly disorders characterized by delayed gastric emptying. The insulin or composition comprising same are to be administered enterally.
US10046031B2	Use of ultrarapid acting insulin Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.
US10046025B2	Stabilizing alkylglycoside compositions and methods thereof The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a cyclic polypeptide.
US10046022B2	Synthetic peptide that increases radiosensitivity of tumor cells and use of same Provided are a synthetic peptide that increases the radiosensitivity of tumor cells and a pharmaceutical composition containing that synthetic peptide.The peptide provided by the present invention is a synthetic peptide having a radiosensitizing peptide sequence including the following amino acid sequence: CX2X3KX5X6X7X8C (wherein, X2 represents K or R, X3 represents S or A, X5 represents S or A, X6 represents R or G, X7 represents R or D and X8 represents S or P); or, a modified amino acid sequence in which one, two or three amino acid residues are substituted, deleted and/or added in that amino acid sequence. In addition, the pharmaceutical composition provided by the present invention is a composition used to increase the sensitivity of tumor cells to radiation in tumor radiation therapy, and contains the synthetic peptide described above.
US10046020B2	Inflammation inhibiting compounds The present invention relates to the use of compounds selected from the group consisting of Lys-(D)Pro-Thr, N-acyl Lys-(D)Pro-Thr, C-amide Lys-(D)Pro-Thr, and C-esters of Lys-(D)Pro-Thr; or a pharmaceutically acceptable salt of said compound for the treatment of inflammatory disorders. The invention also relates to the use of αMSH for inducing tolerance.
US10046016B2	Mutant adeno-associated virus virions and methods of use thereof The present invention provides mutant adeno-associated virus (AAV) that exhibit altered capsid properties, e.g., reduced binding to neutralizing antibodies in serum and/or altered heparin binding and/or altered infectivity of particular cell types. The present invention further provides libraries of mutant AAV comprising one or more mutations in a capsid gene. The present invention further provides methods of generating the mutant AAV and mutant AAV libraries, and compositions comprising the mutant AAV. The present invention further provides recombinant AAV (rAAV) virions that comprise a mutant capsid protein. The present invention further provides nucleic acids comprising nucleotide sequences that encode mutant capsid proteins, and host cells comprising the nucleic acids. The present invention further provides methods of delivering a gene product to an individual, the methods generally involving administering an effective amount of a subject rAAV virion to an individual in need thereof.
US10046015B2	Compositions comprising bacterial strains The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
US10046006B2	Compounds and methods for reducing the recruitment and/or migration of polymorphonuclear cells Methods for reducing recruitment, migration, or both recruitment and migration of polymorphonuclear cells to a site of inflammation in an organ of a human patient comprise administering locally to the organ or systemically to the patient in need thereof an isolated oligonucleotide selected from the group consisting of SEQ ID NO: 8 (IDX9059); SEQ ID NO: 14 (IDX9052); SEQ ID NO: 7 (IDX9054); SEQ ID NO: 6 (IDX9045); SEQ ID NO: 1 (IDX9005); SEQ ID NO: 9 (IDX9074); SEQ ID NO: 3 (IDX9022); SEQ ID NO: 2 (IDX9010); SEQ ID NO: 4 (IDX9030); and SEQ ID NO: 13 (IDX0150).
US10045999B2	Nutritional composition for the stimulation of muscle protein synthesis The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.
US10045994B2	Agents for treating multiple myeloma The present invention relates to the use of compounds of a cannabinoid nature for inhibiting viability with increasing doses of myeloma cell lines. Furthermore, said compounds have been shown not to affect CD34+ cells (normal hematopoietic progenitors) in terms of viability and proliferation. For this reason, the invention paves the way for the use of compounds of a cannabinoid nature as a promising therapy against multiple myeloma and related diseases.
US10045992B2	7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5 (1h)-one, salts thereof and methods of using the same in combination therapy This disclosure relates, at least in part, to a method of treatment. In one embodiment, the method of treatment comprises administering to a subject in need of such treatment a first therapeutic agent including compound (1): or a pharmaceutically acceptable salt thereof in combination with a second therapeutic agent, wherein the first therapeutic agent and the second therapeutic agent are administered either simultaneously or sequentially.
US10045989B2	Quinazoline derivatives, compositions, and uses related thereto The disclosure relates to quinazoline derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to inhibitors of NADPH-oxidases (Nox enzymes) and/or myeloperoxidase.
US10045987B2	Imidazoyl anilide derivatives and methods of use The present invention provides kinase inhibitor analogs with improved properties, such as improved efficacy, pharmacokinetics, safety, and specificity. In some embodiments, the present invention provides nilotinib analogs that provide therapeutic benefits.
US10045985B2	Heteroaryl compounds as BTK inhibitors and uses thereof The present invention relates to pyrimidine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
US10045981B2	Selective kinase inhibitors The present disclosure relates to methods of modulating (for example, inhibiting) activity of JAK3, comprising contacting the JAK3 with a compound of Formula I or pharmaceutically acceptable salt thereof, wherein constituent members are provided hereinwith. The present disclosure further provides novel compounds and compositions as well as their methods of preparation and use. The disclosed JAK3 inhibitors may be used in the treatment of JAK3-associated diseases including, for example, inflammatory and autoimmune disorders.
US10045979B2	Anthelmintic compounds The present invention relates to novel anthelmintic compounds of formula (I) below: wherein Y and Z are independently a bicyclic carbocyclic or a bicyclic heterocyclic group, or one of Y or Z is a bicyclic carbocyclic or a bicyclic heterocyclic group and the other of Y or Z is alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heterocyclyl or heteroaryl, and variables X1, X6, X8, Q1, Q2, Q3, Q4, Q5, Q6, Ring A, Ring B, W, W′, R2, R3, R, R′, m, n and q are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.
US10045978B2	Treatment of mastocytosis with masitinib The treatment of mastocytosis, and in particular indolent forms of mastocytosis (including smoldering systemic, indolent systemic and cutaneous mastocytosis), including the administration of a tyrosine kinase inhibitor or a mast cell inhibitor, especially masitinib or a pharmaceutically acceptable salt or solvate thereof, in particular in an appropriate dosage regimen.
US10045975B2	Methods and ophthalmic devices used in the treatment of ocular allergies Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.
US10045974B2	2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors The present invention is directed to compounds of formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of Aβ deposits is beneficial such as Alzheimer's disease.
US10045972B2	Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating inflammatory, neurodegenerative, or immune-mediated diseases Provided herein are hydroxypyridone derivatives, for example, a compound of Formula I, and pharmaceutical compositions thereof. Also provided herein are methods for treating, preventing, or ameliorating one or more symptoms of an inflammatory, neurodegenerative, or immune-mediated disease (e.g., multiple sclerosis).
US10045971B2	Compositions for treating amyotrophic lateral sclerosis The present invention relates to compositions and methods for the treatment of amyotrophic lateral sclerosis. More specifically, the present invention relates to novel combinatorial therapies for treating amyotrophic lateral sclerosis or a related disorder.
US10045969B2	Isoxazoline-substituted benzamide compound and pesticide A substituted alkenylbenzene compound of formula (4): wherein X1 is selected from the group consisting of halogen atom, —SF5, C1-C6halo alkyl, hydroxy C1-C6haloalkyl, C1-C6alkoxy C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6 haloalkoxy, C1-C3haloalkoxy C1-C3haloalkoxy, C1-C6haloalkylthio, C1-C6haloalkylsulfinyl and C1-C6haloalkylsulfonyl; X3 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy and C1-C6 alkylthio; X4 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, C1-C4alkyl, C1-C4alkoxy and C1-C4haloalkoxy; R3 is —C(R3a)(R3b)R3c, where R3a and R3b independently of each other are a halogen atom, or R3a and R3b together form 3- to 6-membered ring together with the carbon atom bonding them by forming a C2-C5haloalkylene chain, and R3c is selected from the group consisting of a hydrogen atom, halogen atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy and C1-C4haloalkylthio, with a proviso that in case where X1 is a fluorine atom, chlorine atom or trifluoromethyl, and both X2 and X3 are a hydrogen atom, in case where both X1 and X2 are fluorine atom and X3 is a hydrogen atom, and in case where both X1 and X2 are trifluoromethyl and X3 is a hydrogen atom, R3c is a hydrogen atom, chlorine atom, bromine atom, iodine atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy or C1-C4haloalkylthio.
US10045967B2	Thioureylene liquid compositions The present invention relates to novel liquid compositions and formulations containing a thioureylene compound, a polysaccharide and a liquid vehicle. The compositions and formulations of the invention are useful for dealing with diseases and conditions associated with abnormally high thyroid hormone levels in mammals, such as humans and cats.
US10045965B2	Transdermal formulation containing COX inhibitors Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
US10045964B2	Polymorphic forms of ST-246 and methods of preparation Polymorph forms of 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide are disclosed as well as their methods of synthesis and pharmaceutical compositions.
US10045962B2	Uses of duloxetine HCL medicament in preparing pharmaceutical treatment of cancer Provided in the present invention are uses of duloxetine hydrochloride in preparing a pharmaceutical composition for treatment of cancer.
US10045958B1	Methods of therapeutic monitoring of nitrogen scavenging drugs The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.
US10045957B2	GIP elevation inhibitor A GIP-increase inhibitor, which may be utilized for producing a medicine, a food, or the like, is provided. The GIP-increase inhibitor contains triacylglycerol in which α-linolenic acid accounts for 10% by mass or more of the constituent fatty acid, as an effective ingredient.
US10045955B2	Aqueous gel composition and methods of use The present invention is directed to an aqueous gel composition containing a local anesthetic, a lubricating agent, and a preservative and methods of treating vulvovaginal pain, such as dyspareunia by topically administering said composition.
US10045951B2	Flaxseed lignan complex and its use thereof The invention relates compositions and methods for treating pathological lung conditions using whole-grain flaxseed or flaxseed lignans. Specifically, the invention relates to the dietary use of flaxseed lignans.
US10045949B2	Managing osteoporosis with HMW PEG The present invention relates to the administration of compositions comprising polyethylene glycol, for improving the general gastrointestinal health of an animal increasing growth performance and treating osteopenia, osteoporosis and other bone disorders.
US10045935B2	Transdermal formulation containing COX inhibitors Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a COX-2 inhibitor compounds, processes of preparation thereof and methods of use thereof for the treatment of indications treatable by the active compound.
US10045934B2	Use of a photosynthetic cell extract comprising functional thylakoids in cosmetic compositions The invention relates to cosmetic and topical compositions containing an effective amount of a photosynthetic cell extract comprising a functional thylakoid system. The cosmetic compositions have anti-wrinkle and anti-aging effects on a user's skin. In addition, the photosynthetic cell extract protects skin against ultraviolet A (UVA) and ultraviolet (UVB) damage.
US10045931B2	Composition for forming a film on keratin fibres A composition for providing a film on keratin fibers, the composition comprising an aminosilicone polymer; a silicone resin which is a MQ resin; a thickening system comprising a thickening polymer; water; one or more pigments or one or more colored materials; wherein when drying the composition spread with an average wet thickness of 37 micron the fluidity factor is measured to form a drying curve of fluidity factor over time, wherein the fluidity factor is within the range of 10 Hz to 0.001 Hz within the first 15 minutes of drying and the fluidity factor reduces by at least a factor of 100 within the first 15 minutes of drying; wherein the drying curve of fluidity factor over time is measured according to the fluidity factor measurement method and at 23° C. and ambient conditions. Also associated methods, kits and uses.
US10045927B2	Oral care compositions with reduced surface staining Surface staining can be minimized or eliminated by providing an oral care composition comprising a first film comprising a pigment; and optionally a second film; wherein the first film has a dissolution rate in aqueous media that is inversely proportional to its thickness, wherein the first film is in the form of a particle.
US10045925B2	Skincare formulations and regimens Provided are compositions, comprising a neolignan, ectoin, and a molecule of Formula I: wherein R1, R2 and R3 are independently H, methyl, ethyl, propyl, or isopropyl; wherein X is S or O. In some cases, the molecule of Formula I is ergothioneine (EGT). In some cases, the at least one neolignan is honokiol or a derivative thereof. Honokiol may be provided in the form of magnolia bark extract. Methods of making and using these compositions are also provided.
US10045923B2	Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof Provided are a novel compound having skin-whitening, anti-oxidizing and PPAR activities and a medical use thereof, and the compound has skin-whitening activities for the suppression of tyrosinase, and accordingly, is useful for use in skin-whitening pharmaceutical composition or cosmetic products; has anti-oxidant activities, and accordingly, is useful for the prevention and treatment of skin-aging; and has PPAR activities, and in particular, PPARα and PPARγ activities, and accordingly, is useful for use in pharmaceutical compositions or health foods which are effective for the prevention and treatment of obesity, metabolic disease, or cardiovascular disease.
US10045919B2	Controlled release active agent carrier The present invention relates to carriers for the controlled release of active agents, comprising surface reacted natural or synthetic calcium carbonate, one or more active agents, wherein said one or more active agent is associated with said surface-reacted calcium carbonate, and wherein said surface-reacted natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source. It further relates to the preparation of loaded carriers, as well as their use in different applications.
US10045906B2	Systems and methods for haptic stimulation A system for sexual stimulation includes a first sexual stimulation device having a first sensor and a first actuator and a second sexual stimulation device having a second sensor and a second actuator. The first sexual stimulation device is configured to communicate information from the first sensor to actuate the second actuator of the second sexual stimulation device and the second sexual stimulation device is configured to communicate information from the second sensor to actuate the first actuator of the first sexual stimulation device.
US10045900B2	Method for controlling access to medications The exemplary embodiments herein provide a method for controlling access to medications. The method preferably includes the step of electronically unlocking a lid for a single bin out of a plurality of bins within a delivery module at a first location, to accept a medication into the unlocked bin, where the rest of the bins in the same delivery module remain locked. The method should then engage a mechanical lock on the lid once it has been closed, maintain the bin in a locked state during transport to a second location, and engage a mechanical lock on the delivery module once it has been lowered into a drawer at the second location.
US10045896B2	Standing-up assist tool and walking support device The present invention is provided with a support mechanism for an armrest part that includes a gas spring. The support mechanism supports the armrest part in a state of being able to change a posture between an ordinary posture and a forward-tilt posture when the gas spring is locked, and the support mechanism supports the armrest part so as to make the armrest part move with forming an arc from a sitting corresponding position to a standing corresponding position that is located at a forward upper position when the gas spring is unlocked. A gas spring switch part that does not obstruct the locked state of the gas spring when the armrest part is in the ordinary posture and that releases the locked state of the gas spring at a time when the armrest part is in the forward-tilt posture is arranged between the gas spring and the armrest part.
US10045888B2	Nonwoven material having discrete three-dimensional deformations with wide base openings Nonwoven materials having discrete three-dimensional deformations therein forming protrusions that extend outward from the first surface of the nonwoven material and wide base openings adjacent to the second surface of the nonwoven material are disclosed. The nonwoven materials include multiple fibers that extend from the base of the protrusions to the distal end of the protrusions, and contribute to form a portion of the sides and cap of a protrusion. Such fibers may at least substantially surround the sides of the protrusions.
US10045887B2	Article with elastic distribution and system and method for making same A method is described for making an elasticized absorbent article having a waist opening and a pair of leg openings. First, multiple distributions of elastics are applied on a moving material sheet to form a moving web of an elastic composite. Then, each of a core section and a second material sheet is periodically applied onto the moving web to define a finished web of discrete elastic composite bodies. In subsequent steps, discrete absorbent pants articles are shaped from the finished web.
US10045880B2	Cooling system for patients with fever The cooling system for patients with fever is a mechanical, fluid-based system for cooling patients suffering from fever. The cooling system for patients with fever includes a reservoir for containing a cooling fluid, which is maintained at a desired temperature. A temperature sensor is received in the reservoir. The temperature sensor is immersed in the cooling fluid for measuring the temperature thereof. A chiller is also received in the reservoir for selectively cooling the cooling fluid when the temperature thereof, measured by the temperature sensor, is above a pre-set temperature threshold. The reservoir communicates with a cooling pad, which is formed from a padded layer having at least one channel embedded therein. At least one pump and tubing is provided for circulating the cooling fluid through the reservoir and the cooling pad. In use, the cooling pad is applied to the skin of a patient with a fever.
US10045879B2	Portable hypo/hyperthermia unit A portable heating/cooling device for clinical hypo/hyperthermia with cuffs especially designed for arterial cooling/heating for raising or lowering the body temperature of a patient is operable by battery power or a wide range of available external power, and is usable in the field or in medical transport where such external power sources are not available. The small size, weight, and robust nature of the device allows it to be transported with the patient without the need for additional conveying devices.
US10045878B2	Comfort layer for a collecting bag A collecting bag for human body wastes having a barrier film (20a, 20b) covered by a comfort layer (15) attached to the barrier film in an attachment zone wherein the comfort layer is a textile material that is attached to said barrier film in one or more zones of attachment such that not all of the fiber filaments of the textile material in the attachment zone(s) are embedded in the barrier film material.
US10045875B2	Vest to provide decompression and traction for spine and method of use “Vest to Provide Decompression and Traction for Spine and Method of Use” consists of (1) a thoracic top belt (2) a waist bottom belt, each belt having provision of independent tightening (3) an elastic band connecting both belts, thus making a single vest and ((4) a turn buckle mounted in the back of wearer parallel to sine.)The turn buckle integrally but detachably positioned against the top belt and bottom belt provides upward lifting force to the thorax via the top belt and the downward force to the lumbar via the bottom belt, providing the decompression and traction to the spine.
US10045874B2	Clubfoot orthotic Kits, devices, and methods for treating clubfoot are provided. The devices have two platforms that are attached to a bar. The platforms define slots to allow therapeutically preferred orientations of the platforms when attached to the bar. The kits and devices are simple to use and adjust, with a limited amount of possible settings.
US10045872B2	Reinforced joint support strap and method of application A reinforced support strap and method of application on a joint provides lateral and medial support to a joint and limbs. The support strap comprises, in some embodiments, a resilient body portion having a generally elongated V-shape that encapsulates the joint and is manipulated through rotation or axial movement along the joint and limbs for an enhanced fit. The body portion comprises a base end, an open end, and a pair of termini. The body portion further includes a mount surface that overlays the joint, and an exterior surface. The mount surface adheres to the joint through the use of a fastening mechanism. A reinforcement member, having less resilience than the body portion, may integrates into the body portion through stitching, to provide enhanced stability.
US10045870B2	Support device for gastrointestinal implant The present disclosure provides a support device for a gastrointestinal implant. The support device may include a lumen configured to extend through a submucosal tunnel and a mouth located at a proximal end of the lumen and in fluid communication with the lumen. The mouth may be configured to face proximally within a gastrointestinal tract to receive GI contents, and the mouth may be configured to direct the GI contents into the lumen. The support device may further include a support structure, where the lumen extends through the support structure, and where the support structure is configured to apply an outward radial force on an inner wall of the gastrointestinal tract. An artificial tunnel may extend distally from the support structure, may form at least a portion of the lumen, and may be configured to extend through the submucosal tunnel.
US10045866B2	Prosthetic attachment A prosthetic attachment for a prosthetic limb. A base is attached to the prosthetic limb. The base has a magnet that is surrounded by base valleys and base peaks. An attachment piece is attached to the prosthetic attachment. The attachment piece also has a magnet that is surrounded by attachment piece valleys and attachment piece peaks. The magnetic force between the base magnet and the attachment piece magnet attracts the prosthetic attachment to the prosthetic limb so that the base peaks and valleys mates with the attachment piece peaks and valleys for a secure removable attachment. In a preferred embodiment a locking device is used to further secure the prosthetic attachment to the prosthetic limb. In a preferred embodiment the prosthetic attachment is a prosthetic hand and the prosthetic limb is a prosthetic arm.
US10045865B2	Joint and digit This disclosure relates to the field of prosthetics, more specifically to a pinless anthropomorphic hinge or joint, and a digit comprising one or more phalanges connected by and articulating around pinless joints, whereby the joints provide compliant movement in more than one plane. This disclosure also relates to modular prosthetic systems comprising multiple digits, in particular for partial-hand replacements.
US10045861B2	Inserter for expanding body tissue An elongate inserter has a distal end releasably connected to an expandable device for expanding body tissue and a proximal end including a trigger actuator. The expandable device comprises a superior endplate and an inferior endplate that are movable in an expansion direction relative to each other between opposing tissue surfaces of a body. The inserter includes a lifting platform comprising ramp surfaces that upon operation of the trigger actuator cooperatively engage complementary surfaces of expansion structure within the device to cause the superior and inferior endplates to move relatively away from each other. A driver is supported by the inserter for pushing an insert between the superior and inferior endplates after expansion of the device.
US10045858B2	Intervertebral device and methods of use An intervertebral device comprises a plurality of struts that are rotatably associated with each adjacent strut to form a modifiable inner volume V for bone graft containment.
US10045857B2	Lateral interbody fusion devices, systems and methods According to some embodiments, a method of inserting a lateral implant within an intervertebral space defined between an upper vertebral member and a lower vertebral member includes creating a lateral passage through a subject in order to provide minimally invasive access to the intervertebral space, at least partially clearing out native tissue of the subject within and/or near the intervertebral space, positioning a base plate within the intervertebral space, wherein the base plate comprise an upper base plate and a lower base plate and advancing an implant between the upper base plate and the lower base plate so that the implant is urged into the intervertebral space and the upper vertebral member is distracted relative to the lower vertebral member.
US10045854B2	Joint or segmental bone implant for deformity correction An implant is provided for use in an ankle joint between reconditioned end surfaces established on a distal end of an upper tibia bone and an opposing lower talus bone. The implant comprises a substantially porous rigid component adapted to be anchored against the upper tibia reconditioned end surface and the lower talus reconditioned end surface. The component defining an opening therethrough. An intramedullary nail is configured to pass through the opening in the component when the nail is driven through the talus and into the tibia.
US10045851B2	Resilient interpositional arthroplasty device This disclosure is directed to restoring joints by deploying a resilient interpositional arthroplasty implant. Such implants function to pad cartilage defects, cushion, and replace or restore the articular surface, which may preserve joint integrity, reduce pain and improve function. The implant may endure variable joint compressive and shear forces and cyclic loads. The implant may repair, reconstruct, and regenerate joint anatomy, and thereby improve upon joint replacement alternatives. The walls of this invention may capture, distribute and hold living cells until aggregation and hyaline cartilage regrowth occurs. The implant may be deployed into debrided joint spaces, molding and conforming to surrounding structures with sufficient stability so as to enable immediate limb use after outpatient surgery. Appendages of the implant may repair or reconstruct tendons or ligaments, and menisci by interpositional inflatable or compliant polymer arthroplasties that promote anatomic joint motion.
US10045849B2	Moment induced total arthroplasty prosthetic A prosthetic total knee replacement system comprises a distal femoral implant component, a tibial tray implant component and a fixed bearing tibial tray insert. The fixed bearing tibial tray insert is fixed to the tibial tray and articulates with the distal femoral implant component. The fixed bearing tibial tray insert component has a medial-lateral centerline and a stabilizing post. The stabilizing post has a medial-lateral centerline offset laterally from the medial-lateral centerline of the fixed bearing tibial tray insert.
US10045844B2	Post-implant accommodating lens modification Methods of adjusting an intraocular lens after implantation. In some embodiments the methods include positioning an accommodating intraocular lens within an eye, the intraocular lens comprising an optic portion in fluid communication with a peripheral chamber, wherein movement of a fluid between the peripheral chamber and the optic portion in response to ciliary muscle movement changes the optical power of the lens, and reducing a power of the intraocular lens by causing the fluid to move between the optic portion and the peripheral chamber, wherein the reduction in power of the intraocular lens is not in response to ciliary muscle movement, and wherein the positioning step occurs prior to reducing the power.
US10045842B2	Systems, implants, tools, and methods for treatments of pelvic conditions Described are various embodiments of surgical procedure systems, devices, tools, and methods, useful for treating pelvic conditions in a male or female, the pelvic conditions including incontinence (various forms such as fecal incontinence, stress urinary incontinence, urge incontinence, mixed incontinence, etc.), vaginal prolapse (including various forms such as enterocele, cystocele, rectocele, apical or vault prolapse, uterine descent, etc.), and other conditions caused by muscle and ligament weakness, the devices and tools including devices and tools for anchoring an implant to tissue, devices and tools for transvaginally accessing a posterior region of pelvic anatomy, devices (including certain types of implants, anchors, and tools) for connecting (e.g., adjustably) a vaginal apex to a region of sacral anatomy to provide support to the vaginal apex, and related methods.
US10045839B2	Methods for fabricating dental prostheses Methods of fabricating dental prostheses are provided that include the steps of providing a powder of a dental material, and then selectively melting the powder of the dental material to produce a functionally graded layer of the dental material. Additional layers of functionally graded dental material are then built on top of the initial layer of dental material to thereby produce a three-dimensional dental prosthesis having a functionally graded structure and a desired physical geometry. Dental prostheses produced by the foregoing methods are also provided.
US10045834B2	Method for producing a customized orthodontic appliance The present disclosure is directed, at least in part, to a self ligating orthodontic bracket system that includes a rotatable member for securing an archwire within a slot of a bracket. Embodiments of the orthodontic bracket system disclosed herein include a bracket body containing the archwire slot as well as tie wings for attaching various orthodontic devices (e.g., elastomeric bands) to the bracket. The rotatable member is rotatable in a first direction (e.g., counter clockwise) relative to a body of the bracket for securing or locking the archwire within the slot, and for rotating in an opposite direction (e.g., a clockwise direction) relative to the bracket body for unsecuring or unlocking the archwire so that it is substantially unrestrained from exiting the slot. Other embodiments include an orthodontic appliance and method of producing and using the same, and preferably employed in a lingual orthodontic system, that includes friction reducing features between an interior of an archwire slot portion of the appliance and an archwire placed within the archwire slot.
US10045831B2	Instrument tracking in OCT-assisted surgery Systems and methods are provided for a microscope-integrated intraoperative scanner system having automated tracking of an instrument tip. A scanning mirror is configured such that a field of view of the OCT system is determined by a position or orientation of the scanning mirror. A drive system is configured to control the scanning mirror. Camera assemblies are configured to determine respective two-dimensional projections of the positions of markers attached to a surgical instrument. A stereo vision system is configured to determine a three-dimensional location of each of the markers from the determined two-dimensional positions. An instrument tracking component is configured to determine a position of a working tip of the surgical instrument according to the determined three-dimensional locations. A drive control is configured to instruct the drive system to adjust the scanner mirror to control the field of view of the OCT system.
US10045826B2	Systems and methods for repairing bone with multiple tools A method for repairing a bone of a patient may include superimposing a first virtual boundary on a virtual bone and superimposing a second virtual boundary on the virtual bone. The method may further include robotically modifying the bone of the patient with a planar tool along a first working boundary to create a first surface. The first working boundary may correspond to the first virtual boundary. The method may further include robotically modifying the bone of the patient with a rotary tool along a second working boundary to create a second surface. The second working boundary may correspond to the second virtual boundary.
US10045825B2	Partial facial recognition and gaze detection for a medical system A medical system automatically identifies a user based on matching a partial facial image of the user with a database of authorized users. The medical system automatically configures based on the user identification and received patient data. The medical system further automatically identifies a patient based on matching a facial image of the patient with an image of the patient to confirm the correct patient is in the operating room. The medical system still further provides for gaze detection and gesture control by a user such that the user in the sterile environment can directly control devices outside the sterile environment.
US10045820B2	Internet connected dermatological devices and systems A dermatological treatment and analysis system includes a handheld treatment device having a handheld body, a treatment radiation source that delivers a dermatological treatment to the skin, and skin sensor(s) configured to generate signals indicative of one or more skin properties. A wireless transmitter is integrated in the handheld treatment device or in a docking/charging station that receives the handheld treatment device. The wireless transmitter is configured to receive skin-related data comprising the signals from the at least one skin sensor and/or information derived from such signals, and to wirelessly transmit the received skin-related data for analysis of the skin-related data by a remote data analysis system, which may analyze the received skin-related data to generate skin analysis data, and communicate the skin analysis data as feedback to the user of the handheld treatment device, e.g., via a website or application hosted on an internet-connected device of the user.
US10045818B2	Treatment tool for endoscope and incision system A treatment tool for an endoscope includes a sheath which is extended along a longitudinal axis; a pre-curved portion which is disposed at a distal portion of the sheath; a knife wire lumen which is formed along the longitudinal axis of the sheath; a first communication hole and a second communication hole which are open on an outer circumferential surface to communicate the outer circumferential surface positioned with the knife wire lumen; a wire-shaped cutting portion which is protruded from the first communication hole and the second communication hole, and is extended in a position spaced from the outer circumferential surface and the virtual plane; a fixing portion which is provided to fix an end portion of a wire connected to the cutting portion inside the knife wire lumen, and a bending portion which is provided to bend the wire.
US10045814B2	Endoscopic instrument for tissue identification A method for identifying and treating tissue includes providing an electrosurgical treatment device including an electrode assembly. One or more electrical property values of target tissue are measured. The measured electrical property values of the target tissue are compared against electrical property values of known tissue types. A tissue type of the target tissue is identified. An energy delivery configuration of the electrosurgical treatment device is adjusted to the type of target tissue. The electrosurgical treatment device is activated to treat the target tissue.
US10045810B2	High frequency surgical generator comprising an additional transformer An HF surgical appliance comprising an HF generator having an output circuit, which contains an output transformer and has an output impedance. Output terminals, to which an HF surgical instrument can be connected, are provided, said instrument supplying a high-frequency current with a specific frequency into tissue to treat the same. An additional output circuit containing an additional transformer, which is connected between the output circuit and the output terminals to reduce the output impedance is also provided. In this way, the HF surgical appliance can be operated with a high power output even on loads having low impedance.
US10045806B2	Device for the mixing and storing of polymethylmethacrylate bone cement Device for the mixing of polymethylmethacrylate bone cement and for storing a monomer liquid and a cement powder as starting components of the bone cement, comprising a cartridge having an internal space closed on one side by a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container which can be opened in the device so that the monomer liquid flows from the monomer container into the device; and a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge; having a pumping plunger that can be shifted axially in the hollow cylinder arranged in the hollow cylinder, which can be used to push monomer liquid from the hollow cylinder through the connecting conduit into the internal space of the cartridge by actuating the pumping plunger.
US10045803B2	Sacroiliac joint fusion screw and method A sacroiliac joint fusion screw and associated delivery tools and method. Embodiments of the sacroiliac joint fusion screw comprise a shaft having proximal and distal end portions and a head on the proximal end of the shaft. A threaded portion on a distal portion of the shaft is configured to engage a sacrum. A glide zone portion on the shaft between the threaded portion and the proximal end portion is configured to extend through an ilium. The screw can provide stability and compression to the joint.
US10045801B2	Bone stabilization device and method of production The present disclosure discloses a bone stabilization device (also referred to as a bone tape), which includes a composite flexible construct including a rigidifiable biocompatible sheet structure having first and second opposed surfaces. A biocompatible cement is located on the first surface. In use the composite flexible construct is applied to a bone with the cement contacted directly to the bone. The cement is made of a material that, once adhered to the bone, is curable to mechanically and/or ionically bond to the sheet structure and to chemically bond to the bone to achieve a permanent bond. The bone tape allows simultaneous alignment and stabilization of multiple articulated fragments for successful 3D reconstruction of shattered bones. Initial flexibility and translucency provided by the bone tape can facilitate the temporary stabilization and alignment adjustment of multiple fragments, prior to permanent rigid bonding.
US10045798B2	Composite implant coating A coating layer, for example PEEK or titanium foil, shields a bone implant surface from wearing interactions with surfaces of bone and/or other implants. The coating prevents shedding particles which are difficult to distinguish from evidence of potentially dangerous conditions, for example, microorganism contamination and/or degenerating tissue. Methods and structures for securing a coating layer are described. Other uses and implementations of coating layers are described.
US10045796B2	Spinal correction system and method A spinal correction system comprises a first member configured for attachment to a first portion of vertebral tissue and a second member is configured for attachment to a second portion of the vertebral tissue spaced from the first portion. A third member has a non-flexible configuration relative to the first and second members and is configured for attachment to an apical portion of the vertebral tissue and along at least a portion of at least two vertebrae. The third member extends between a first end connected to the first member at a first transition configured for attachment to the first vertebral tissue and a second end connected to the second member at a second transition configured for attachment to the vertebral tissue. Methods of use are disclosed.
US10045790B2	Device and method for treating vascular occlusion A system and method for managing an occlusion, such as a blood clot, within a lumen or passageway of a patient. More particularly, a system and method for rapidly restoring blood flow through an occlusion including a self-expanding, tubular member through which blood may flow when in an expanded state. The tubular member has a structure configured to engage the occlusive material, thereby allowing for extraction of at least a portion of the occlusive material. The system may further employ a material extraction member that is deployed distally of the tubular member.
US10045789B2	Universal surgical guide systems and methods Devices, systems, and methods are provided for ligament repair procedures, and can be used to establish a location and trajectory for forming a bone tunnel in bone. One exemplary embodiment of a surgical guide for using in a ligament repair procedure includes a guide arm and a carriage that can be selectively locked along the guide arm to define an angle of the bone tunnel. The guide arm also defines a location of a distal end of the bone tunnel. In some embodiments the carriage is configured to have a bullet side-loaded into it, and the bullet can be used to define a location of a proximal end of the bone tunnel. The present disclosure also provides for a gage that limits the distance a drill pin that drills the bone tunnel can travel. A variety of other, devices, systems, and methods are also provided.
US10045787B2	Orthopedic device holder system Orthopedic device holder systems including a quick connect between an orthopedic device holder and an orthopedic tool are disclosed. The orthopedic device holder can include a shaft having a shaft connection end including at least three shaft engaging surfaces. The orthopedic tool can have a tool connection end including at least three tool engaging surfaces configured to couple with the three shaft engaging surfaces of the orthopedic device holder.
US10045784B2	Devices and methods for ligating anatomical structures Devices and methods for ligating anatomical structures are provided herein. In particular, the devices and methods provided herein can be used to ligate the left atrial appendage. The ligating devices (10, 110, 210, 310, 410) comprise a ligating element (30, 130, 230, 330, 430) and a control element (40, 140, 240, 340, 430) which controls the opening of the ligating element in a loop or lariat shape. Some embodiments comprise also a positioning element (50, 150) which help position the ligating element. In some embodiments a conduit (250) is provided for deploying the ligating element by inflating control.
US10045782B2	Surgical stapling loading unit with stroke counter and lockout A surgical loading unit for use with a handle assembly includes an elongate outer frame, an end effector mounted to a distal end of the outer frame, a drive at least partially disposed within the outer frame and operatively coupled to the end effector, and a rotatable counter mounted to the outer frame and adapted for rotational movement about the longitudinal axis. A counter actuator is mounted to the drive and dimensioned to engage the rotatable counter to cause rotational movement of the rotatable counter through an arc segment of rotation during each firing stroke of the drive.
US10045781B2	Closure lockout systems for surgical instruments A surgical instrument is disclosed. The surgical instrument can include a first jaw, a second jaw, and a jaw closure lockout system. The first jaw can comprise a pivot pin slot and a slide pin slot. The second jaw can comprise an anvil and, in addition, a mounting portion comprising a pivot pin, which can be movably positioned in the pivot pin slot. A shiftable guide can be movably positioned in the first jaw and can comprise a body and a barrier wall. The body can comprise a slide pin movably positioned in the slide pin slot. The barrier wall can be aligned with a portion of the pivot pin slot when the slide pin is positioned within a range of positions in the slide pin slot, and the barrier wall can be offset from the pivot pin slot when the slide pin is positioned outside the range of positions.
US10045780B2	Method of applying staples in lower anterior bowel resection A method for manipulating tissue of a patient includes a surgical instrument having a handle assembly, a shaft assembly, and an end effector. The method includes positioning a tissue within a gap between a cartridge and an anvil and against a guide pin to laterally position the tissue relative to the cartridge and the anvil. The method also includes moving a retaining pin from an open position to a closed position to capture the tissue and moving the cartridge toward the anvil in a closed configuration. Furthermore, the method includes inhibiting deflection of a distal end portion of the end effector wherein at least at least one of the guide pin or the retaining pin connects to the distal end portion. The method further includes forming a plurality of staples within the tissue and cutting the tissue with a knife.
US10045778B2	Robotically-controlled motorized surgical instrument with an end effector A surgical tool for use with a surgical system is disclosed. The surgical tool comprises a housing containing three drive motors and three non-concentric rotatable output members, a modular shaft assembly comprising three rotatable drive shafts coupled to the three non-concentric rotatable output members, an end effector comprising a first jaw and a second jaw, and a motion conversion assembly. The motion conversion assembly is operably coupled to one of the drive motors and an axial drive assembly. The motion conversion assembly is configured to convert a rotational motion of one of the three rotatable drive shafts to an axial motion. The application of the axial motion to the axial drive assembly approximates the first jaw from an open position to a closed position and performs an actuation stroke within the end effector.
US10045775B1	Arterial closing device and method An arterial closure device includes an elongated catheter having a proximal end, an opposing flexible distal end, and a lumen extending between the proximal end and the distal end. An externalization needle and an internal catheter are disposed within the lumen. The externalization needle is in communication with a first plunger. A first threading needle and a second threading needle are positioned in separate threading channels and in communication with a second plunger. A suture has a first end attached to the second end of the first threading needle and a second end attached to the second end of the second threading needle. A primary aperture extends through a wall of the elongated catheter. A first threading aperture and a second threading aperture extend through the wall of the elongated catheter at opposing sides of the primary aperture.
US10045769B2	Circular surgical staplers with foldable anvil assemblies Circular stapling instruments and anvil assemblies. The anvil assemblies may have collapsible anvil support members that may be inserted through an opening in a patient and then expanded to be attached to an anvil plate assembly that has a staple-forming surface thereon. The anvil support member is attachable to the anvil plate assembly in such a way that when the anvil assembly is coupled to the stapling head of a circular stapler, the staple-forming surface is in substantial registry with the staples supported in the stapling head. A variety of different anvil support members and anvil plate assemblies are disclosed.
US10045768B2	Methods and devices for surgical access Devices, systems and surgical methods for achieving surgical access to a site within the body, particularly the spine. The system includes a modular retractor with a body and hood that are independently operable at their proximal ends to manipulate soft tissue at their distal ends, and may be adjustably and releasably coupled to form an open channel to a target tissue. On insertion, the hood is at least partially compressed against the retractor body. When coupled, the retractors are displaced from one another and constrained to one or more of at least three degrees of freedom, movable pivotally around a proximal end pivot axis that is perpendicular to the channel to adjust displacement of the retractors at their distal ends, displaceable vertically to adjust the distance between the retractors at their proximal ends, and slidable horizontally along the channel axis.
US10045763B2	Endoscopic treatment tool set An endoscopic treatment tool set includes: an endoscopic treatment tool that includes a sheath having a lumen, an elongated shaft inserted into the lumen and the elongated shaft having an insertion passage, a stylet disposed in the insertion passage, an implant connected to the stylet, and a manipulation part provided at the sheath; and a jig. The endoscopic treatment tool is packed together with the jig. The jig is coupled to a proximal end portion of the stylet disposed in the manipulation part and the jig is configured to be movable relative to the manipulation part. The implant is connected to the jig via the stylet, and the implant is configured such that the jig is pulled toward a proximal end side of the manipulation part so that the stylet is moved to a proximal end side in the insertion passage and the implant is loaded in the insertion passage.
US10045762B2	Dilation device and expandable covering for a dilation instrument A dilation device including a dilation instrument which includes a distal radially expandable section which is coupled via an elongate shank to a handling section, and an expandable covering with a closed distal end and an open proximal end, for the expansion section of the dilation instrument. The covering has a shank section extending along the shank of the dilation instrument. The open proximal end of the covering is detachably coupled to the distal end of the handling section of the dilation instrument. Furthermore, the covering is disclosed per se, which consists of a mesh material and has a shank section, which is connected to a coupling sleeve at the open proximal end.
US10045759B2	Epicutaneous patch test chamber A test chamber for epicutaneous patch test units is provided. The test chamber is formed of a multilayer material including at least one absorbent layer and at least one barrier layer. The test chamber is adapted to contain a liquid or petrolatum-based allergen. The absorbent layer absorbs the liquid or petrolatum-based allergen, while the barrier layer prevents the allergen from migrating out of the test chamber.
US10045755B2	Perfusion imaging system with a patient specific perfusion model A perfusion analysis system includes a perfusion modeller and a user interface. The perfusion modeller generates a patient specific perfusion model based on medical imaging perfusion data for the patient, a general perfusion model, and a quantification of one or more identified pathologies of the patient that affect perfusion in the patient. The user interface accepts an input indicative of a modification to the quantification of the one or more identified pathologies. In response, the perfusion modeller updates the patient specific perfusion model based on the medical imaging perfusion data for the patient, the general perfusion model, and the quantification of the one or more identified pathologies of the patient, including the modification thereto.
US10045753B2	Structure, method for manufacturing the same, and talbot interferometer A structure includes a silicon substrate having a plurality of recessed portions, each recessed portion having a bottom and a side wall, silicide layers, each silicide layer in contact with the bottoms of the plurality of recessed portions, and a metal structure including metal portions, each metal portion disposed in the plurality of recessed portions and in contact with the silicide layers. The silicide layers are electrically connected to each other through the silicon substrate.
US10045752B2	Method for coded-source phase contrast X-ray imaging Described here is a method for performing phase contrast imaging using an array of independently controllable x-ray sources. The array of x-ray sources can be controlled to produce a distinct spatial pattern of x-ray radiation and thus can be used to encode phase contrast signals without the need for a coded aperture. The lack of coded aperture increases the flexibility of the imaging method. For instance, because a fixed, coded aperture is not required, the angular resolution of the imaging technique can be increased as compared to coded-aperture imaging. Moreover, the lack of a radioopaque coded aperture increases the photon flux that reaches the subject, thereby increasing the attainable signal-to-noise ratio.
US10045745B2	Radiation blocking unit, radiographic imaging apparatus, and radiographic imaging method The present invention provides a radiation blocking unit including: an attachment member that is attachable between sources and an object table surface to which radiation from a radiation source and visible light from a visible light source are emitted, the sources including the radiation source and the visible light source; a radiation blocking portion, disposed on the attachment member, that transmits the illuminated visible light to an overlapping incidence region on the object table surface in which an incidence region of the radiation and an incidence region of the visible light overlap, and that blocks the irradiated radiation outside the overlapping incidence region; and a visible light blocking portion, disposed on the attachment member, that transmits the irradiated radiation to the overlapping incidence region, and blocks the illuminated visible light outside the overlapping incidence region.
US10045741B2	System and method for real-time frequency correction for magnetic resonance imaging Systems and methods for estimating frequency drifts in magnetic resonance signals acquired with a magnetic resonance imaging (“MRI”) system are provided. In one example, the frequency drifts are estimated from phase-correction data that are obtained during an echo-planar imaging (“EPI”), or other multiecho imaging, scan. The systems and methods of the present invention provide for efficiently and accurately computing frequency drift values that can be used for real-time, prospective frequency drift correction.
US10045739B2	Analyte sensor sensitivity attenuation mitigation Method and apparatus for receiving a first signal from a first working electrode of a glucose sensor positioned at a first predetermined position under the skin layer, receiving a second signal from a second working electrode of the glucose sensor positioned at a second predetermined position under the skin layer, the second signal received substantially contemporaneous to receiving the first signal, detecting a dropout in the signal level associated with one of the first or second signals, comparing the first signal and the second signal to determine a variation between the first and second signals, and confirming one of the first or second signals as a valid glucose sensor signal output when the determined variation between the first and the second signals is less than a predetermined threshold level are provided.
US10045735B2	Biofeedback sensors in a body area network Technologies for the sensing of biofeedback signals of a user include a body area network (BAN) system comprising one or more biofeedback sensors and one or more BAN controllers. The biofeedback sensors are configured to sense BAN signals, which may include biofeedback signals and body-coupled communication (BCC) signals. To facilitate communication, the biofeedback sensors may demultiplex the sensed BAN signals into biofeedback signals and incoming BCC signals. Similarly, the biofeedback sensors may multiplex outgoing BCC signals with sensed biofeedback signals. The BAN controller may communicate in a similar manner. Additionally, the BAN controller may process incoming BCC signals and provide feedback to the user based on BCC signals received from the biofeedback sensors.
US10045729B2	Head tilt response The present invention relates to the estimation of the vertical in humans using an experimental design that incorporates virtual reality. Methods of measuring the perceived vertical in a subject using steady state and transient experiments are disclosed. The inventive methods are useful for diagnosis, as well as for follow up after patient rehabilitation.
US10045721B2	Apparatus, system, and method for automatic power reduction in photoplethysmography and pulse oximetry systems Systems, apparatuses and methods may provide for a transmit circuit including a light source and a receive circuit including a photodetector and a transimpedance amplifier (TIA) coupled to the photodetector. Additionally, a calibration circuit may be coupled to the transmit circuit and the receive circuit, wherein the calibration circuit includes a current controller to set an operational current of the light source to a minimum value that results in a target output voltage of the receive circuit. In one example, the gain of the TIA remains substantially constant during calibration of the receive circuit.
US10045717B2	WiFi-based person-identification technique for use in smart spaces The disclosed embodiments relate to the design of a system that identifies a person. During operation, the system receives channel state information (CSI) for a set of orthogonal frequency division modulation (OFDM) subcarriers while the person moves in a region that includes two or more nodes that use the set of OFDM subcarriers to communicate with one another. Next, the system analyzes the CSI to obtain an analysis result. The system then determines the identity of the person based on the analysis result.
US10045715B2	Self-compensating bed scale system for removable components A patient support apparatus includes detectors and a controller operable to automatically update a tare weight for use in determining a true patient weight. The detectors are configured to produce signals indicating a presence or absence of a corresponding removable component. The controller is configured to determine weights of each and every removable component on the patient support apparatus and store each weight in a memory. The controller is further configured to receive the signals produced by the detectors and detect any addition or removal of removable components of the patient support apparatus, update the tare weight, and determine a weight of a patient being supported on the patient support apparatus.
US10045708B2	Method of detecting the wearing limb of a wearable electronic device A wearable device configured to acquire and process electrocardiographic measurements, detect lead inversion and correct the acquired measurements for lead inversion is provided. In one example, the wearable device can detect lead inversion by first assessing whether the P-wave of a given electrocardiographic measurement has a negative amplitude, and if the P-wave is found to be negative, the device can determine if the magnitude of the R-wave is smaller than the maximum of the magnitudes of the S-wave and the Q-wave. In another example, the device can be put through an enrollment procedure in which electrocardiographic measurements are taken with the device being worn at known locations on the body. Once the enrollment procedure is completed, when the device is being used, any electrocardiographic results obtained can be compared against the measurements taken during the enrollment phase, and the location of the device on the body can be determined.
US10045707B2	Basket catheter with far-field electrode Cardiac catheterization is performed with a catheter having a basket-shaped assembly at its distal end. A plurality of spline electrodes are disposed on the splines of the assembly. The assembly is configurable in an expanded arrangement wherein the splines bow radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis of the catheter body. A far-field electrode is disposed in the interior of the assembly. An intracardiac electrogram and a far-field electrogram are obtained with at least one of the spline electrodes and the far-field electrode, respectively. The far-field component is removed from the intracardiac electrogram using the far-field electrogram.
US10045704B2	Method for laparoscopic nerve detection and mapping A surgical method aids identification of nerves in a body to help prevent damage to the nerves during surgery to the body proximate the nerves. An electrode introduced to within a body cavity through a catheter is placed proximate a nerve within the body cavity by a laparoscopic or robotic device. An exploratory probe placed in the body cavity is selectively placed along a presumed pathway of the nerve to provide an electrical signal through the nerve to the electrode. An analyzer interfaced with the electrode analyzes the electrical signal received at the electrode to determine the proximity of the exploratory probe to the nerve, allowing mapping of the nerve pathway through the body cavity.
US10045697B2	System for transcutaneous monitoring of intracranial pressure A system for measuring and converting to an observer intelligible form an internal physiological parameter of a patient. The invention allows transcutaneous telemetry of intracranial pressure via a system which includes a patient implanted sensor module and an external processing module, optically coupled to the sensor module via an external coupling module. A sensor within the sensor module transduces the measured pressure and a near infrared emitter transmits the telemetry when interrogated by the external coupling module. A set of tuned inductor-crystal circuits comprised in part of a cylindrical crystal oscillator whose resonant frequency is sensed by a dipper circuit arrangement is provided. Power for the sensor module is derived inductively through rectification of a transcutaneously-applied high-frequency alternating electromagnetic field generated within the external coupling module. A computer within the processing module calculates the physiological parameter from the telemetry signal and represents this data in numerical, graphical, or analog format.
US10045695B2	Dental imaging apparatus The invention relates to a dental imaging apparatus which includes an x-ray imaging means and at least one color camera for photographing the face of a patient positioned at the imaging station of the apparatus, which at least one color camera is arranged to image the patient's face positioned at the patient support station from different directions, and means arranged into functional connection with said at least one color camera for creating a virtual three-dimensional texture model of the patient's face.
US10045694B2	Integrated diagnostic device A flexible, integrated, urine-based diagnostic device designed such that one or more diagnostic channels are integrated into the body of the device. Each diagnostic channel is designed to contain an immunoassay to detect the presence of a selected analyte so that the device can return a visible readout indicating the presence of the analyte. The flexibility of the device aids the user in the sample collection process.
US10045693B2	Ophthalmologic observation apparatus An ophthalmologic observation apparatus of an embodiment includes a photographing optical system, measuring optical system, optical-path coupler, first and second drivers and controller. The photographing optical system includes a first focusing lens and performs photography for acquiring a front image of an eye. The measuring optical system includes a second focusing lens and performs OCT for acquiring a cross-sectional image of the eye. The optical-path coupler couples optical paths of the photographing optical system and measuring optical system at a location on the eye side than the first and second focusing lenses. The first driver moves the first focusing lens along an optical axis of the photographing optical system. The second driver moves the second focusing lens along an optical axis of the measuring optical system. The controller controls the first and second drivers individually.

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