Document Document Title
US09803339B2 Hydraulic control device and operating machine having the same
A hydraulic control device includes: a recovery oil passage; a regenerative motor that rotates an output shaft of an engine in response to a supply of the hydraulic fluid and is driven to rotate by rotation of the output shaft of the engine; a regenerative oil passage for guiding return oil from a boom cylinder to the regenerative motor without passing the return oil through the recovery oil passage; a coupling oil passage that couples the recovery oil passage and the regenerative oil passage to each other; and a regeneration-side check valve that is provided on the coupling oil passage, and allows the hydraulic fluid to flow from the recovery oil passage toward the regenerative motor, and moreover restricts the hydraulic fluid from flowing from the regenerative motor toward the recovery oil passage.
US09803338B2 System and method for recovering energy and leveling hydraulic system loads
A hydraulic system including an accumulator and a hydraulic transformer is disclosed. The hydraulic transformer includes first and second variable displacement pump/motor units mounted on a rotatable shaft. The rotatable shaft has an end adapted for connection to an external load. The first variable displacement pump/motor unit includes a first side that fluidly connects to a pump and a second side that fluidly connects to a tank. The second variable displacement pump/motor unit includes a first side that fluidly connects to the accumulator and a second side that fluidly connects with the tank.
US09803337B2 System and method for in-pit crushing and conveying operations
A control system implemented for in-pit crushing and conveying (IPCC) operations employing a shovel machine and a crusher machine is provided. The shovel machine includes an implement configured to excavate a material from a worksite and load the material into a hopper of the crusher machine. The control system includes a position determination module, an excavation determination module, and a path determination module. The path determination module is configured to determine one or more travel paths, with a plurality of loading positions, for the shovel machine and the crusher machine. The plurality of loading positions is based at least in part on the relative position of the shovel machine and the crusher machine and a plurality of excavation positions, such that at each of the plurality of loading positions, the implement traverses an arc passing above the hopper.
US09803336B2 System and method for determining dump locations
A system for determining a plurality of dump locations for a blade includes a position sensor and a controller configured to determine the position of a work surface and determine a plurality of dump locations along a path between a start location and an end location based upon the position of the work surface and a desired target. Adjacent pairs of dump locations define a load spacing distance and each load spacing distance is sequentially longer along the work surface closer to the start location.
US09803335B1 Integrated CB microphone control
A control system of a work machine including an operator's cab and an implement, the system comprising a vehicle control unit for controlling the machine; a first control device located in the cab for controlling a steering function of the machine; a second control device located in the cab for controlling the implement; a CB transceiver located in the cab, the CB transceiver configured to receive and transmit signals; and a CB microphone control disposed on the first control device or the second control device, the CB microphone control being operably actuable between an active position and an inactive position, where in the active position the transceiver is enabled to transmit a signal, and in the inactive position the transceiver is enabled to receive a signal.
US09803333B2 Hydraulic system for working machine
A hydraulic system includes: hydraulic actuators; a control valve for controlling the hydraulic actuators; a tank for storing a hydraulic operation fluid; a variable displacement pump for supplying the hydraulic operation fluid to the hydraulic actuators; a regulator for controlling the variable displacement pump; a pilot pump for discharging a hydraulic pilot fluid; a load sensing system for maintaining a differential pressure to be a constant pressure, the differential pressure being obtained by subtracting a second signal pressure from a first signal pressure that is the discharge pressure of the variable displacement pump, the second signal pressure being the maximum one of the load pressures generated in the hydraulic actuators; a signal tube for sending the second signal pressure to the regulator; a throttle provided on the signal tube; and a warm-up circuit for supplying the hydraulic pilot fluid to a downstream side of the throttle.
US09803332B2 Excavation bucket and work vehicle
An excavation bucket includes a bottom face part, a rear face part, a pair of opposing side wall parts, teeth, a bracket, and a target penetration depth display component. The target penetration depth display component is provided around the teeth and near an end of the side wall part that forms an edge of an opening, and displays the target penetration depth. A wrist radius is an imaginary line segment connecting a center of a first hole in the bracket and the distal end of the teeth in side view. The target penetration depth display component is provided to an inside of at least one of the pair of opposing side wall parts and at a position of the side wall part corresponding to a position that has moved along the imaginary line segment from the distal end of the teeth by a specific proportional length of the wrist radius.
US09803328B2 Floatable support structure for an offshore wind turbine or other device
An apparatus for supporting an additional structure near a surface of a body of water, and a system which includes the apparatus and further includes the structure attached to the apparatus. The apparatus and the system are each configured to assume a rest position and orientation when the apparatus or system is floating at the surface and when the body of water is substantially still, where the rest orientation defines a vertical direction extending from the surface to a keel at a lowermost position of the apparatus. The apparatus includes a support member, which, in use, is attached to the additional structure; and buoyant units. Each buoyant unit is attached to the support member at or near the keel and extends from the keel in a longitudinal direction of the buoyant unit, which longitudinal direction defines an angle of approximately 35°-65° with respect to the vertical direction.
US09803326B2 Bridge system adapted for promoting sedimentation
A system providing environmentally friendly pathway tunnel utilizes a bottom configuration with multiple elongated beams and slots. One or more of the beams includes upstanding sedimentation members that are spaced apart along a span of the tunnel. The system interacts with the flowing water and earthen material in the flowing water such that capture and settling of the earthen material at locations along the tunnel occurs to produce a more natural water flow pathway along the tunnel.
US09803325B2 Ejector unit for a road milling machine or the like
The invention relates to an ejector unit, in particular for a road milling machine, having an ejector that is replaceably mounted on a carrier. In one aspect the ejector is curved in a scoop-like fashion. In another aspect the ejector is reversible upon the carrier to allow the ejector to be reversed after one wear surface is worn, thus presenting a new second wear surface.
US09803324B2 Ejector control for spreading material according to a profile
In accordance with an example embodiment, a method of operating a work vehicle with an ejector body may include receiving a position signal indicative of a position of the work vehicle, receiving a target profile indicative of a target topography for an area, receiving an ejection command at a controller and entering the controller into an ejection mode based on the ejection command, and controlling, with the controller, in the ejection mode, at least one of a speed of the work vehicle and a speed of an ejector included in the ejector body based on the position signal and the target profile, to spread a load of material from the ejector body onto a ground surface.
US09803320B2 Dry cellulose filaments and the method of making the same
The present invention relates to dry cellulose filaments and particularly those that are re-dispersible in water. Dry cellulose filaments comprise at least 50% by weight of the filaments having a filament length up to 350 μm; and a diameter of between 100 and 500 nm, wherein the filaments are re-dispersible in water. Also described here is a film of dry cellulose filaments comprising the filaments described, wherein the film is dispersible in water. A method of making a dry film of cellulose filaments is also described that includes providing a liquid suspension of the cellulose filaments described; and retaining the filaments on the forming section of a paper or tissue making machine or on a modified paper or tissue making machine. The film can be optionally converted to powders or flakes for shipment, storage or subsequent uses. The filaments, the film, the powders or flakes and the method are in a preferred embodiment free of additives and the derivatization of the filaments.
US09803318B2 Spreader roll
A spreader roll has a stationary shaft mounted at both ends and running in a curve. A roll shell is supported on the shaft. The construction is simplified in that said roll shell is rotatably mounted, is formed of a flexible material and is supported on the shaft via a lubricating fluid film.
US09803315B2 Cationizing agent, method for firmly fixing water-insoluble particles, and method for producing dyed material
A cationizing agent for cationizing a cloth prior to the firm fixing of water-insoluble particles onto the cloth, said cationizing agent comprising a polymer having a constituent unit (a1) derived from a vinylamine monomer represented by formula (1). (In the formula, R1 represents a hydrogen atom or a methyl group.)
US09803310B1 Appliance interface and input chassis
An appliance, including an interface and input chassis is provided. Appliance may include a contact plate, a conductive spring, and a support wall. The input chassis may define a connection aperture extending therethrough. The contact plate may be disposed above the connection aperture of the input chassis. The contact plate may include a top surface facing away from the input chassis and a bottom surface facing toward the input chassis. The conductive spring may be coupled the contact plate at the bottom surface of the contact plate. The conductive spring may extend through the connection aperture. The support wall may be attached to the input chassis and disposed about the conductive spring between the contact plate and the connection aperture of the input chassis.
US09803308B2 Balancer and washing machine having the same
A balancer includes a balancer housing having an annular channel defined therein, at least one mass movably disposed in the channel, and at least one magnet coupled to one side of the balancer housing to restrain movement of the mass along the channel when rotational speed of a drum of the washing machine is within a predetermined range. The magnet includes a plurality of unit magnets arranged in a circumferential direction of the balancer housing.
US09803306B2 Clothes treatment apparatus and a method for controlling a clothes treatment apparatus
A clothes treatment apparatus and a method for controlling a clothes treatment apparatus are provided. The method may include feeding heated hot air to clothes or other items received in a drum, and dehydrating the clothes or other items by performing a first rotation cycle for rotating the drum at a first RPM for a predetermined period of time. The first RPM may be a RPM that allows a centrifugal force applied to the clothes or other items during rotation of the drum to exceed gravity.
US09803303B2 Multilayered pipe valve insulation cover
A multilayered nonwoven insulating barrier with an integral pocket for installation of a component to be insulated. The insulating barrier has nonwoven layers that overlap one another and are stitched to one another by first pair of seams to form an integral pocket therebetween. An elastic member is secured to one end of the insulating barrier to facilitate wrapping the end around and forming a seal. A second elastic member is secured to an opposite end of the insulating barrier to facilitate wrapping the second end around and forming a seal. A releasable member is secured along a first lateral side of the insulating barrier and a mating releasable member is secured along an opposite second lateral side of the insulating barrier and the releasable members facilitate releasable wrapping of the insulating barrier about and forming a seal with the component.
US09803301B1 Hydroformed composite material and method for making same
A hydroformed composite material includes an expanded spun bonded nonwoven layer having a loft of at least about 1.3 times greater than an original loft of an original unexpanded spun bonded nonwoven web from which the expanded spun bonded nonwoven layer was created, and an air permeability of at least about 1.2 times greater than an original air permeability of the original unexpanded spun bonded nonwoven web. The hydroformed composite material includes a formed film layer that includes a plurality of extended cells containing continuous fibers and/or fibrils of the expanded spun bonded nonwoven layer.
US09803300B2 Knit sock with targeted compression zone
A knit sock includes a foot portion having an upper instep area and a lower sole area integrally knit of a body yarn in circumferential courses and axial wales. The lower sole area defines inner and outer arch regions. The inner arch region incorporates a targeted compression zone adapted to reside generally adjacent an inner arch of a wearer's foot. The compression zone includes axially extending compression ridges of variable length spaced apart from a top of the compression zone to a bottom of the compression zone. When the sock is worn, a compression force applied by the foot portion within the targeted compression zone is greater than the compression force in directly adjacent areas of said foot portion.
US09803299B2 Knitted component for an article of footwear including a full monofilament upper
An article of footwear including a full monofilament upper is described. The full monofilament upper incorporates a knitted component including a monofilament knit element. The monofilament knit element is formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures.
US09803297B2 Device for guiding fibre tows through oxidation furnaces
The invention relates to an apparatus for passing at least one fiber tow multiple times through an oxidation furnace by means of godets, the at least one fiber tow being diverted via at least one godet that is arranged offset. According to the invention, the godet comprises a shaft on which at least two single rollers are arranged to be mounted, each single roller being arranged so as to be rotatable on the shaft.
US09803293B2 Method for producing group III-nitride wafers and group III-nitride wafers
The present invention discloses a production method for group III nitride ingots or pieces such as wafers. To solve the coloration problem in the wafers grown by the ammonothermal method, the present invention composed of the following steps; growth of group III nitride ingots by the ammonothermal method, slicing of the ingots into wafers, annealing of the wafers in a manner that avoids dissociation or decomposition of the wafers. This annealing process is effective to improve transparency of the wafers and/or otherwise remove contaminants from wafers.
US09803291B2 Crucible for growing sapphire single crystal, and method for producing crucible for growing sapphire single crystal
An object of this invention is to provide a crucible for growing a sapphire single crystal, which is optimized for providing a sapphire single crystal and is reusable. A crucible for growing a sapphire single crystal of this invention includes: a base material (3) containing molybdenum as a main component and having a crucible shape; and a coating layer (5) with which only an inner periphery of the base material (3) is coated and which is formed of tungsten and inevitable impurities, in which the coating layer (5) has a surface roughness Ra of 5 μm or more and 20 μm or less.
US09803290B2 High temperature steam electrolysis facility (HTSE) with allothermal hydrogen production
A high temperature steam electrolysis or fuel cell electric power generating facility, including at least two electrochemical reactors fluidly connected in series to each other by their cathode compartment(s). At least one heat exchanger is arranged between two reactors in series, a primary circuit of the heat exchanger being connected to an external heat source configured to provide heat to fluid(s) at an outlet of an upstream reactor prior to be introduced at an inlet of a downstream reactor.
US09803276B2 Method and apparatus for producing low-particle layers on substrates
The invention relates to methods and devices for producing one or more low-particle layers on substrates in a vacuum. The layers are deposited onto the substrate from a cylindrical source material, optionally together with a reactive gas component, by means of magnetron sputtering. The layer is deposited against the force of gravity in a sputter-up method. During the method or within the device, the structure or stochiometric atomic composition of the layers can optionally be modified using a plasma source. Multiple sputtering sources with different source materials can be provided in the device such that multiple layers of different compositions can be applied on the substrate at a high speed in one process.
US09803275B2 Method for manufacturing graphene composite electrode material
The present invention provides a method for manufacturing a graphene composite electrode material, including the following steps: (1) providing a glass substrate, the glass substrate having a melting point greater than 1100° C.; (2) washing the glass substrate and then forming a metal film on the glass substrate; (3) patterning the metal film to form a circuit pattern; and (4) forming a graphene film on the circuit pattern so as to form a graphene composite electrode material. The method for manufacturing a graphene composite electrode material according to the present invention uses a temperature resistant glass substrate and a metal catalyst to directly grow a graphene film on a circuit pattern thereby requiring no transfer, not affected by solvent applied in transfer, having relatively high quality of film formation, requiring no etching, allowing for direct formation of a graphene composite electrode material, having a simple process, providing an effect of protection of the metal circuit pattern due to stable chemical property of graphene, and thus effectively extending the service life of the graphene composite electrode material.
US09803270B2 Method for hot-dip coating of a steel flat product
A method which allows process-stable hot-dip coating of Ni-alloy steel flat products in a cost- and resource-effective manner, including the following steps: a) provision of a steel flat product obtained by cold- or hot-rolling; b) within 1-30 s, heating the steel flat product to a holding temperature between 700 and 1100° C., under a heating atmosphere of N2; c) holding the steel flat product at the holding temperature for a holding duration of 10-120 s under a holding atmosphere of N2; d) cooling the steel flat product from the holding temperature to a strip inlet temperature of 430-800° C.; and e) passing the steel flat product through an inlet zone, in which an inert or reducing inlet atmosphere predominates, and passing the steel flat product through a melt bath, wherein TP1>TP2>TP4.
US09803269B2 α+β type titanium alloy and production method therefor
The present invention provides an α+β type titanium alloy and a production method therefor, which has an ultrafine structure causing superplasticity under low temperatures and has a high deformation ratio compared to conventional α+β type Ti alloys. The alloy has an ultrafine structure made of equiaxial crystals in which an area ratio of crystals having a grain diameter of 1 μm or less is 60% or more, and maximum frequency grain diameter is 0.5 μm or less, wherein a portion in which the integration degree of plane orientation of the hexagonal close-packed crystal is 1.00 or more exists within a range of 0 to 60 degrees with respect to a normal line of a processed surface of the alloy.
US09803265B2 Metal matrix composite
The present invention relates to a metal matrix composite (MMC). The MMC includes a preform formed from a composition having ceramic particles and ceramic fibers and defining a plurality of voids. The metal matrix composite also includes a support element, such as a metal, disposed within the voids of the preform. The MMC has a wear surface defined by both the preform and the support element.
US09803264B2 High-plasticity free-cutting zinc alloy
The present invention relates to a high-plasticity free-cutting zinc alloy, which includes the following components in percentage of weight: 1-10% Cu, 0.1-3.0% Bi, 0.01-1.5% Mn, 0.001-1% Ti and/or 0.01-0.3% Zr, optional component X, optional component Y, and a remainder component being Zn having less than or equal to 0.01% unavoidable impurities, wherein component X amounts to 0-1.0% and includes at least one element selected from Cr, V, Nb, Ni and Co; and component Y amounts to 0-1.0% and includes at least one element selected from B, As, P and rare earth metal. Compared with existing zinc alloys, the present invention has good machinability, higher plasticity and improved processability, which can be widely used in F connectors, pen manufacturing, socket connectors, locks and etc.
US09803263B2 Method for manufacturing a wear resistant component
A method for manufacturing a wear resistant component, includes the steps of: providing a mould defining at least a portion of the component; providing a powder mixture comprising a first powder of tungsten carbide and a second powder of a cobalt-based alloy, wherein the powder mixture comprises 30-70 vol % of the first powder of tungsten carbide and 70-30 vol % of the second powder of the cobalt-based alloy and the second powder of cobalt-based alloy comprises 20-35 wt % Cr, 0-20 wt % W, 0-15 wt % Mo, 0-10 wt % Fe, 0.05-4 wt % C and balance Co, wherein the amounts of W and Mo fulfills the requirement 4
US09803262B2 Gallium extraction agent and gallium extraction method
Provided are an extraction agent and extraction method that selectively extract and, at a low cost, recover gallium from an acidic solution containing gallium and zinc. The gallium extraction agent comprises an amide derivative represented by general formula (I). In the formula, R1 and R2 each indicate the same or different alkyl group, R3 indicates a hydrogen atom or an alkyl group, and R4 indicates a hydrogen atom or any given group, other than an amino group, bonded to the α-carbon as an amino acid. The general formula preferably has a glycine unit, a histidine unit, a lysine unit, an aspartic acid unit, or an N-methylglycine unit. By extracting gallium from an acidic solution containing gallium and zinc by means of solvent extraction using the extraction agent, it is possible to selectively extract gallium.
US09803261B2 Method for improving quality of titanium-containing feedstock
A technique is provided, in which impure metal is efficiently separated and removed from titanium-containing raw material such as titanium slag or ilmenite and high titanium-containing raw material is produced. The method for improving quality of titanium-containing raw material containing slag, including steps of: oxidizing the titanium-containing raw material, selectively chlorinating impurities in the titanium-containing raw material, and separating and removing the impure chlorides to obtain high titanium-containing raw material. Alternatively, in this method, the oxidizing treatment and the selective chlorinating treatment are performed simultaneously.
US09803260B2 Use of cationic surfactants in the cyanidation of refractory carbonaceous ores for recovery of metals
A process for recovery of precious metals from ores or concentrates containing refractory carbonaceous material by cyanidation leaching. The process involves addition to the ores or concentrates at least one cationic surfactant before or during the addition of cyanide-containing solution. The agent enables the recovery of precious metals by cyanidation from high preg-robbing carbonaceous ores and improves the recovery of precious metals by cyanidation from medium to low preg-robbing carbonaceous ores. The agent also prevents froth and foaming formation during the cyanidation process.
US09803258B2 Post processing of components that are laser peened
A method of post processing a laser peened component to remove a laser remelt layer is proposed. The post processing includes a series of steps including grit blasting, chemical etching and mechanical finishing the component. This will ensure that the mechanical property (i.e., damage tolerance) benefit of laser peening is restored to the surface of the component.
US09803256B2 High performance material for coiled tubing applications and the method of producing the same
Embodiments of the present disclosure are directed to coiled steel tubes and methods of manufacturing coiled steel tubes. In some embodiments, the final microstructures of the coiled steel tubes across all base metal regions, weld joints, and heat affected zones can be homogeneous. Further, the final microstructure of the coiled steel tube can be a mixture of tempered martensite and bainite.
US09803255B2 Aqueous quenching media and use thereof in quenching metal substrates
Aqueous media for quenching metal substrates are provided and contain (i) a polyvinylpyrrolidone/polyvinylcaprolactam copolymer and (ii) one or more of a second polymer, which is selected from (a) a substituted oxazoline polymer; (b) a poly(oxyethylene-oxyalkylene)glycol; or (c) a polyvinylpyrrolidone polymer. The quenching bath provides reduced cooling rates through the martensite temperature ranges. Also provided are processes for quenching metal substrates using these quenching media.
US09803252B2 Virus causing respiratory tract illness in susceptible mammals
The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
US09803246B2 Receptor gene for peptide cancer antigen-specific T cell
The invention provides the nucleotide sequence and amino acid sequence of the CDR3 domain of the T cell receptor (TCR) gene of a WT1-specific cytotoxic T cell (CTL) against WT1 protein. Also provided are a method for testing for and treating cancer using the nucleotide sequence and amino acid sequence, and a chip, primer set, kit, and device for testing for cancer comprising the nucleotide sequence and amino acid sequence.
US09803245B2 Signature for predicting clinical outcome in human HER2+ breast cancer
A method of predicting outcome in a subject with for example Her2+ (ERα−) breast cancer comprising: (a) determining a HTICs expression signature comprising determining an expression level of 2 or more HTICS biomarkers selected from Aurkb, Ccna2, Scrn1, Npy, Atp7b, Chaf1b, Ccnb1, Cldn8, Nrp1, Ccr2, C1qb, Cd74, Vcam1, Cd180, Itgb2, Cd72, St8sia4, Kif11, Plk1, Chek1, Mphosph6, Cora1a, Ccl5, Cd3e, Hcls1, Vav1, Plek, Arhgdib, Il2rg, Sash3, Lck, Il2rb, Cybb, Cd79b, Sell, Ccnd2, Tnfrsf1b, Rftn1, Rac2 and Ly86; and (b) calculating a signature score, the signature score comprising a sum of HTICs biomarker expression parameters; wherein a signature score greater than a selected cut-off or control signature score is indicative of a poor outcome (HTICS+) and a signature score less than a selected cut-off is indicative of a good outcome (HTICS−). The methods can be used to prognose outcome and/or select suitable treatment. Arrays and kits for use with the methods are also provided.
US09803244B2 Methods of determining eosinophilic gastritis status based on marker or gene expression
The disclosure provides compositions and methods related to the diagnosis, prognosis, and treatment of inflammatory diseases and disorders, especially allergic inflammatory diseases and disorders.
US09803236B2 Microarray-based assay integrated with particles for analyzing molecular interactions
A microarray-based assay is provided, which is used for analyzing molecular interactions, including polynucleotides, polypeptides, antibodies, small molecule compounds, peptides and carbohydrates. Such method comprises coupling a target molecule to a particle and then binding to a probe molecule on microarray. In particular, multiplexed genetic analysis of nucleic acid fragments can be implemented. Specific genes, single nucleotide polymorphisms or gene mutations, such as deletions, insertions, and indels, can be identified. Coupled with microarray, the particles, themselves or further modified, facilitate the detection of results with non-expensive devices or even naked eyes. This technology enables the detection and interpretation of molecular interactions in an efficient and cost effective way.
US09803233B2 Recognition-release nanoporous substrate comprising active agents, methods of their preparation and uses
The present invention relates to a porous substrate comprising at least one active agent entrapped within said pores of said substrate; wherein said pores are capped by at least one nucleic acid sequence; said agent is being released by a triggered reaction of said capping sequence with at least one analyte (biomarker) thereby allowing said capping to be cleaved from said pore. The invention further relates to methods of manufacturing said substrate, uses thereof for the controlled administration of active agents and diagnostic of conditions in a patient.
US09803228B2 Electrochemical sensor strip
A method of making an electrochemical sensor strip that includes: depositing a first electrode on a base; depositing a second electrode on the base; applying a first layer onto the first electrode; and applying a second layer onto the second electrode. The first layer includes an oxidoreductase and a mediator. The second layer includes a soluble redox species.
US09803226B2 Emulsion systems and emulsion-based amplification of nucleic acid
Methods for efficient and high throughput emulsion-based nucleic amplification are provided. In some aspects, emulsion mixtures are provided that require extremely low input energy (e.g., the energy generated by pipetting) to form emulsions that are effective for nucleic acid amplification. Efficient formulations for breaking emulsions are likewise provided.
US09803225B2 Means and methods for the enzymatic production of L-methionine from O-phospho-L-homoserine and methanethiol
Provided is a method for producing L-methionine in which O-phospho-L-homoserine and methanethiol are enzymatically converted into L-methionine and H3PO4. Such a conversion is achieved by an enzyme called O-phospho-L-homoserine (OHPS) dependent methionine synthase. Also described are O-phospho-L-homoserine (OHPS) dependent methionine synthases, i.e. proteins which are able to enzymatically convert O-phospho-L-homoserine and methanethiol into L-methionine and H3PO4 as well as microorganisms which have been genetically modified so as to be able to produce L-methionine from O-phospho-L-homoserine and methanethiol. Furthermore described are methods to screen for enzymes that catalyze the conversion of O-phospho-L-homoserine and methanethiol into L-methionine and H3PO4.
US09803224B2 Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
US09803222B2 Processing biomass
Biomass (e.g., plant biomass, animal biomass, microbial, and municipal waste biomass) is processed to produce useful products, such as food products and amino acids.
US09803221B2 Engineering microorganisms to increase ethanol production by metabolic redirection
The present invention provides for the manipulation of carbon flux in a recombinant host cell to increase the formation of desirable products. The invention relates to cellulose-digesting organisms that have been genetically modified to allow the production of ethanol at a high yield by redirecting carbon flux at key steps of central metabolism.
US09803219B2 Adenovirus derived helper virus for enhancing recombinant parvovirus production
Described is an adenovirus derived helper virus which may comprise the adenoviral DNA sequences for E2a, S4 (orf6), the VA1 RNA gene, and the parvovirus VP capsid gene unit. Also described is a method of efficiently preparing a recombinant parvovirus (particle) which is based on the use of various adenoviral derived helper viruses/vectors.
US09803216B2 Genetically-engineered newcastle disease virus as an oncolytic agent, and methods of using same
Recombinant strains of avian paramyxovirus (APMV), such as Newcastle disease virus (NDV), are provided. Also provided are compositions comprising them, and methods of using them to lyse tumor cells and to treat cancer. In certain aspects, genetically-engineered viral strains that incorporate therapeutic transgenes are also provided. The recombinant viruses may be used in accordance with methods of providing enhanced oncolytic efficacy and delivering an oncolytic virus to tumors present in a patient. Also provided are methods for identifying a recombinant virus as an oncolytically-effective agent.
US09803212B2 Regulation of translation of heterologously expressed genes
The present invention pertains to a method of expressing a protein of interest, preferably a heterologous protein, in preferably a plant. In a preferred embodiment said plant is a doubled haploid homozygous transgenic Nicotiana tabacum plant silenced for Ntp303. Furthermore, the invention relates to said plant with or without nucleic acid constructs according to the invention. Propagation, harvest and tissue material of said transgenic Nicotiana tabacum plant is also a part of the invention.
US09803209B2 Bacterial mutants with improved transformation efficiency
Provided herein are Lactobacillus mutants having improved transformation efficiency, comprising a disruption to an endogenous gene encoding a restriction modification system protein. Also described are methods for producing the mutants, methods for generating transformants using the mutants, and methods for producing a polypeptide or fermentation product using the mutants.
US09803206B2 Therapeutic agent for treating Trypanosoma-associated disease, method for killing Trypanosoma parasites, and use thereof
A therapeutic agent for treating a Trypanosoma-associated disease; a method of preventing infection by Trypanosoma parasites, or killing Trypanosoma parasites; and use thereof, the therapeutic agent and the method each using a mechanism different from a mechanism used in conventional technology. The therapeutic agent of the present invention for treating a Trypanosoma-associated disease includes, as a medicinal component, an antisense oligonucleotide suppressing the expression of an inositol 1,4,5-trisphosphate receptor protein of Trypanosoma parasites.
US09803201B2 Disulfide-containing alkyne linking agents
Described are improved disulfide-containing alkyne linking agents having have branched disulfides. The improved linking agents exhibit improved stability. The linking agents are useful for attachment of oligonucleotides to targeting groups or delivery agents.
US09803199B2 Cationic lipid
The present invention provides a compound represented by the formula (Ia) as a novel cationic lipid that forms a lipid particle and also provides a lipid particle comprising the compound. The present invention further provides a nucleic acid lipid particle containing the lipid particle, and a pharmaceutical composition containing the nucleic acid lipid particle as an active ingredient.
US09803194B2 Compositions and methods of nucleic acid-targeting nucleic acids
This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof.
US09803193B2 Protein screening methods
The invention provides methods and compositions useful for identifying polypeptides with desired characteristics in vitro.
US09803192B2 Programmable and reconfigurable microcolumn affinity chromatography device, system, and methods of use thereof
The present invention generally relates to microcolumn affinity chromatography devices, systems that include the microcolumn affinity chromatography devices of the present disclosure, methods of using the devices and the systems of the present disclosure, and methods of making the devices and the systems of the present disclosure. In certain embodiments, the microcolumn affinity chromatography device is suitable for conducting affinity chromatography in multiple microcolumns in parallel and/or in series.
US09803187B2 Baulamycins, compositions and methods of use thereof
Provided herein are compositions of compounds of formula (I), methods of inhibiting a bacterial infection by contacting a cell with a composition comprising a compound of formula (I), and methods of isolating compounds of formula (I) from an extract of Streptomyces tempisquensis.
US09803183B2 Expression vectors for an improved protein secretion
The aim of the invention is to improve the secretion of a protein from a host cell in order to increase the product yield of protein in a fermentation process. This is achieved by an expression vector comprising a promoter sequence and a nucleic acid sequence that codes for a protein. The protein comprises a signal peptide and an additional amino acid sequence, and the signal peptide comprises an amino acid sequence that is at least 80% identical to the amino acid sequence specified SEQ ID NO: 2, at least 80% identical to the amino acid sequence specified in SEQ ID NO: 4, at least 80% identical to the amino acid sequence specified in SEQ ID NO: 6, or the signal peptide comprises an amino acid sequence that is structurally homologous to at least one of said sequences.
US09803182B2 Ionic liquid-tolerant cellulase enzymes
The present invention provides ionic liquid-tolerant cellulases and method of producing and using such cellulases. The cellulases of the invention are useful in saccharification reactions using ionic liquid treated biomass.
US09803178B2 Biocatalysts for the preparation of hydroxy substituted carbamates
The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides, vectors, host cells, and methods of making and using the ketoreductase polypeptides.
US09803177B2 Induced pluripotent stem cells with synthetic modified RNAs
Described herein are synthetic, modified RNAs for changing the phenotype of a cell, such as expressing a polypeptide or altering the developmental potential. Accordingly, provided herein are compositions, methods, and kits comprising synthetic, modified RNAs for changing the phenotype of a cell or cells. These methods, compositions, and kits comprising synthetic, modified RNAs can be used either to express a desired protein in a cell or tissue, or to change the differentiated phenotype of a cell to that of another, desired cell type.
US09803172B2 Method for inducing bacteria to enter into viable but nonculturable state
A method induces bacteria to enter into viable, but nonculturable state. The method includes subjecting a target bacterium to high pressure carbon dioxide treatment so as to make it enter into the viable, but nonculturable state, which can be demonstrated experimentally. The viable but nonculturable state can be entered quickly, such as within one hour.
US09803171B2 Method for making dehydrated mycelium elements and product made thereby
A living hydrated mycelium composite containing at least one of a combination of mycelium and fibers, mycelium and particles, and mycelium, particles and fibers is processed with a nutrient material to promote mycelia tissue growth; thereafter dehydrated to a moisture content of less than 50% by weight to deactivate the further growth of mycelia tissue; and then stored. The stored dehydrated mycelium composite is further processed by rehydrating to reactivate the mycelium and to initiate growth of at least one fruiting body.
US09803169B2 Microplate-based apparatus for measuring cell metabolism
A microplate-based apparatus for measuring cell metabolism is provided. The apparatus is capable of providing automation of all procedures, ranging from drug injection into each well of a microplate to the measurement of dissolved-oxygen (DO) concentration and hydrogen ion concentration.
US09803167B2 Stretching apparatus and method for aligning microfibrils
The present disclosure relates to stretching apparatus and method for aligning microfibrils. Specifically, the present disclosure provides an apparatus for aligning microfibrils along a single direction, which includes: a first elastic substrate onto which a composition containing microfibrils is loaded; and a stretching module which stretches the width of the elastic substrate. In accordance with the apparatus the present disclosure, microfibrils or cells may be aligned along a particular direction simply by pulling and then releasing the elastic substrate. The present disclosure is also useful for culturing of the aligned cells because the physiological activity of the cells can be maintained and cytotoxicity can be prevented.
US09803163B2 Systems for carbonating customized beverages
A system for carbonating a personalized beverage may comprise a base container including at least one sidewall defining a liquid storage area, and a carbon dioxide storage member configured to be sealingly coupled to said base container. The system may further comprise a carbon dioxide cartridge configured to selectively release carbon dioxide when engaged with said carbon dioxide storage member, and wherein said carbon dioxide storage member further comprises a pressure regulator configured to, when actuated, release the said carbon dioxide from said carbon dioxide cartridge at a rate configured to carbonate a beverage within said liquid storage over a period of time greater than 6 hours and less than 36 hours.
US09803160B2 Moderately alkaline cleaning compositions for proteinaceous and fatty soil removal at low temperatures
The present invention comprises chlorinated and non-chlorinated alkaline cleaning compositions for removal of proteinaceous and fatty soils at low temperature, i.e. less than 120° F., with little or no deleterious affect on cleaning performance. According to the invention, applicants have found that adding additional alkalinity makes protein removal more difficult and reducing the amount of alkalinity actually improves performance. According to the invention optimized combinations of chlorine and alkalinity components for low temperature cleaning as well as a surfactant system optimized for low temperature fatty soil removal are disclosed.
US09803159B2 Method of making oil-and-fat
A method of making an oil-and-fat capable of being used as a non-tempering hard butter of a non-lauric acid type, having a sharp melting property (meltability in the mouth), a good compatibility with a cacao butter and a low trans-fatty acid content, includes fractionating an oil-and-fat A comprising a first non-laurin-based oil-and-fat containing 50 to 100 mass % of SUS type triglyceride and a non-laurin-based transesterification oil containing 12 to 38 mass % of SSU type triglyceride or an oil-and-fat B obtained by partially hydrogenating the oil-and-fat A so as to obtain a soft portion.
US09803154B2 Process for preparing a para-branched alkyl-substituted hydroxyaromatic compound
Disclosed herein is a process for preparing an isomeric mixture comprising a major amount of a para-branched mono-alkyl-substituted hydroxyaromatic compound. The process involves the steps of: (a) providing an isomeric mixture comprising a major amount of a para-di(alkyl-substituted)aromatic compound; wherein a first alkyl substituent is a C3 to C8 alkyl moiety and a second alkyl substituent is a C4+n to C8+n branched alkyl moiety, wherein n is 0 to 42 and further wherein the second alkyl substituent is at least one carbon atom greater than the first alkyl substituent; (b) subjecting the isomeric mixture comprising a major amount of a para-di(alkyl-substituted)aromatic compound to oxidation conditions in the presence of an oxygen-containing source, thereby converting the first alkyl substituent which is a C3 to C8 alkyl moiety to a hydroperoxide-containing substituted moiety to produce an isomeric mixture comprising a major amount of a para-branched alkyl-substituted, hydroperoxide-containing substituted aromatic compound; and (c) converting the hydroperoxide-containing substituted moiety to a hydroxyl moiety thereby providing an isomeric mixture comprising a major amount of a para-branched mono-alkyl-substituted hydroxyaromatic compound.
US09803150B2 System and apparatus for processing material to generate syngas in a modular architecture
System for processing material to generate syngas in a modular architecture may include a plurality of primary reactor chambers and a shared secondary reactor chamber. Each primary reactor chamber includes electrodes protruding into the chamber, the electrodes operable to generate an arc capable to generate first-stage gas from breakdown of the material when electricity is applied to the electrodes. The secondary reactor chamber is operable to receive the first-stage gas generated by the plurality of primary reactor chambers and to receive water vapor. The gas generated within the plurality of primary reactor chambers combine and interact with the water vapor to form second-stage gas. Turbulence can be generated within the secondary reactor chamber to improve mixing of the first-stage gas with the water vapor. Powering of each of the primary reactor chambers can be done with a different phase of power from a multi-phase input to ensure balanced power utilization.
US09803148B2 Hydrocracking process with interstage steam stripping
In a hydrocracking process, the product from the first stage reactor passes through a steam stripper to remove hydrogen, H2S, NH3, light gases (C1-C4), naphtha and diesel products. The stripper bottoms are separated from hydrogen, H2S, NH3, light gases (C1-C4), naphtha, and diesel products and treated in a second stage reactor. The effluent stream from the second stage reactor, along with the stream of separated hydrogen, H2S, NH3, light gases (C1-C4), naphtha, and diesel products, are passed to a separation stage for separating petroleum fractions. Preferably, the effluent stream from the first stage reactor is passed through a steam generator prior to the steam stripping step. In an alternate embodiment, the effluent stream from the first stage reactor is passed through a vapor/liquid separator stripper vessel prior to the steam stripping step.
US09803146B2 Hydrocarbon residue upgradation process
The present subject matter provides a process for hydrocarbon residue upgradation. The combination of the hydrocarbon residue along with aromatic rich hydrocarbons, catalysts and surfactants allow the operation of visbreaking unit at higher temperature while producing a stable bottom product.
US09803144B2 Upgrading biofuel crude oils with solid sorbents for petroleum refinery processing
The invention relates to removing contaminants from oil using solid sorbents that are comprised primarily of carbon and preferably of coke particles. The coke particles have an affinity for contaminants in oil and are sized to be filtered from oil without plugging. Most contaminants have such a small size that they tend to plug up filters. As the contaminants agglomerate onto the solid sorbent, the resulting particles form a filter cake on conventional filter materials in such a way as to allow the oil to pass on through without significant pressure drop or delay.
US09803142B1 Catalysts and methods for converting carbonaceous materials to fuels
Catalysts and processes designed to convert DME and/or methanol and hydrogen (H2) to desirable liquid fuels are described. These catalysts produce the fuels efficiently and with a high selectivity and yield, and reduce the formation of aromatic hydrocarbons by incorporating H2 into the products. Also described are process methods to further upgrade these fuels to higher molecular weight liquid fuel mixtures, which have physical properties comparable with current commercially used liquid fuels.
US09803140B2 Liquid crystal compound and liquid crystal composition
The present disclosure discloses a liquid crystal compound and a liquid crystal composition. The liquid crystal compound has a general structural formula as represented by formula I. The liquid crystal composition provided by the present disclosure has a lower rotary viscosity γ1, can achieve a quick response, and further has an appropriate dielectric anisotropy Δ∈, an appropriate optical anisotropy Δn, a high stability to heat and light, a high VHR numerical value especially in the case where the liquid crystal is under harsh conditions, and a stability to electric field and electromagnetic radiation. As a liquid crystal material for use in thin film transistor techniques (TFT-LCD), the material further has the properties of a wider nematic phase temperature range, an appropriate birefringence anisotropy, a very high electrical resistivity, a good anti-ultraviolet performance, a high charge holding rate, a low vapor pressure etc.
US09803136B2 Liquid electrolyte-free, solid-state solar cells with inorganic hole transport materials
Photovoltaic cells incorporating the compounds A/M/X compounds as hole transport materials are provide. The A/M/X compounds comprise one or more A moieties, one or more M atoms and one or more X atoms. The A moieties are selected from organic cations and elements from Group 1 of the periodic table, the M atoms are selected from elements from at least one of Groups 3, 4, 5, 13, 14 or 15 of the periodic table, and the X atoms are selected from elements from Group 17 of the periodic table.
US09803130B2 Methods of activating enzyme breakers
A method of treating a subterranean formation, the method including placing a well treatment fluid comprised of at least an enzyme and a breaker additive in the subterranean formation. Initially, the pH of the well treatment fluid is about 11.5. The breaker additive reduces the pH of the well treatment fluid by at least 1.5 to increase the activity of enzyme and accelerate hydrolysis of a crosslinkable component.
US09803129B2 Water-based drilling fluids containing crosslinked polyacrylic acid
A water-based drilling fluid containing high molecular weight crosslinked polyacrylic acid as viscosifying agent exhibits stability at well temperatures in excess of 150° C. The drilling fluid may further contain a lubricant, weighting agent and/or a wetting agent as well as laponite clay. The aqueous based drilling fluid exhibits a coefficient of friction which is substantially close to the coefficient of friction of oil based drilling muds.
US09803128B2 Additive for drilling mud
To provide an additive for drilling mud, used in drilling for petroleum, natural gas, civil engineering, mines, etc., which has high heat resistance and high mechanical shear resistance, of which the viscous property does not degrade even under high-temperature and high-shear conditions; has high pseudoplastic flowability and therefore secures high flowability during discharging; and is a naturally-derived one and is therefore highly biodegradable and has least adverse impact on environment. An additive for drilling mud, which contains cellulose fibers having a number-average fiber diameter of from 2 to 500 nm and a fiber aspect ratio of 50 or more and having a cellulose I-type crystal structure.
US09803127B2 Drilling fluid and process of making the same
Drilling fluids and processes for making drilling fluids for use in environmentally sensitive areas are provided. The environmentally friendly drilling fluid includes a linear olefin portion that includes linear alpha olefins and/or linear internal olefins with carbon numbers of about 6 carbons to about 30 carbons; and an oligomer portion comprising dimers, trimers, tetramers, and/or heavier oligomers of olefins, wherein the olefins have a carbon number of between about 4 carbons and about 24 carbons, and the oligomer portion includes at least about 50 mole percent of trisubstituted olefin. The drilling fluid has a pour point of about −10° C. or lower, a biodegradation ratio of about 1.0 or less, a toxicity ratio of about 1.0 or less, a Marine Bodis of at least about 60%, a flash point of about 110° C. or higher, a viscosity less than about 4 cSt at 40° C., a density of about 0.78 to about 0.83 gram/ml, and a log Pow of greater than about 3.
US09803124B2 Process for producing unitary graphene matrix composites containing carbon or graphite fillers
A process for producing a unitary graphene matrix composite, the process comprising: (a) preparing a graphene oxide gel having graphene oxide molecules dispersed in a fluid medium, wherein the graphene oxide gel is optically transparent or translucent; (b) mixing a carbon or graphite filler phase in said graphene oxide gel to form a slurry; (c) dispensing said slurry onto a surface of a supporting substrate or a cavity of a molding tool; (d) partially or completely removing the fluid medium from the slurry to form a composite precursor; and (e) heat-treating the composite precursor to form the unitary graphene composite at a temperature higher than 100° C. This composite exhibits a combination of exceptional thermal conductivity, electrical conductivity, mechanical strength, surface hardness, and scratch resistance.
US09803122B2 Refrigeration oil composition
The refrigeration oil composition for HFC-based refrigerants or HC-based refrigerants of the invention includes a product of the esterification of an alcohol ingredient including pentaerythritol and dipentaerythritol and a fatty acid ingredient including at least one of a linear or branched fatty acid having 5 carbon atoms and a linear or branched fatty acid having 6 carbon atoms and at least one of a linear or branched fatty acid having 8 carbon atoms and a linear or branched fatty acid having 9 carbon atoms, wherein at least one of the fatty acid having 5 carbon atoms and the fatty acid having 6 carbon atoms in the fatty acid ingredient accounts for 20 to 100% by mol of the total amount of the fatty acid ingredient, and either the alcohol ingredient or the fatty acid ingredient is a mixture.
US09803120B2 Water repellent composition, its production method, hydrophobic substrate treating agent composition and article
A water repellent composition comprising a fluorinated copolymer having structural units based on a monomer (a) having a C1-6 polyfluoroalkyl group, structural units based on a monomer (b) having a C1-6 alkyl group and structural units based on a monomer (c) (halogenated olefin), and a medium, wherein the proportion of the structural units based on the monomer (a) is from 50 to 90 mass % of the structural units (100 mass %) based on all the monomers.
US09803117B2 Frame-sealing agent, display panel and display device
The invention discloses a frame-sealing agent, a display panel and a display device. The frame-sealing agent comprises an acrylic resin, an epoxy resin, a thermal curing agent and an ultraviolet photoinitiator, wherein the frame-sealing agent further comprises a compound which decomposes to produce a gas under a condition of light irradiation, heating or high temperature. In the invention, by providing a compound that decomposes to produce a gas under a condition of light irradiation, heating or high temperature, when the frame-sealing agent is cured, the compound decomposes to produce a gas with the effect of light irradiation, heating or high temperature. The light leak of the display screen at the position of backlight is obstructed by the gas. Additionally, the pressure of the gas can retard the diffusion of liquid crystal molecules, so that the contamination of the liquid crystal caused by the too early contact between the liquid crystal and the frame-sealing agent and the relevant display badness are avoided.
US09803116B2 Binder composition
The invention relates to a new binder composition which is particularly suitable for the manufacture of composite materials utilizing such new binder composition in the required nonwoven materials. Composite materials using such new binder composition in their nonwoven part are suitable, in particular, for composites materials for interior construction, for linings, floor coverings, and for the manufacture of furniture and similar products.
US09803115B2 Adhesive hydrogel and method for electrolytic protection of concrete structure
Disclosed is an adhesive hydrogel containing a polymer matrix, water, and a polyhydric alcohol, wherein the polymer matrix contains a copolymer of a monofunctional monomer with a single polymerizable C—C double bond and a polyfunctional monomer with two or more polymerizable C—C double bonds, the monofunctional monomer contains a nonionic (meth)acrylamide-based monomer, and the polyfunctional monomer has a composition formula: ClHmOn, where O is an oxygen atom in an ether bond, l is an integer greater than or equal to 4, m is an integer greater than or equal to 6, and n is an integer greater than or equal to 0.
US09803113B2 Adhesive compositions of propylene-based and ethylene-based polymers
The present invention is related to adhesive compositions and their applications. In particular, the adhesive compositions described herein comprise a propylene-based polymer and an ethylene-based polymer with varying comonomer content.
US09803111B2 Adhesive for semiconductor, fluxing agent, manufacturing method for semiconductor device, and semiconductor device
An adhesive for a semiconductor, comprising an epoxy resin, a curing agent, and a compound having a group represented by the following formula (1): wherein R1 represents an electron-donating group.
US09803109B2 CMP composition for silicon nitride removal
The invention provides a chemical-mechanical polishing composition comprising: (a) colloidal silica particles that are surface modified with metal ions selected from Mg, Ca, Al, B, Be, and combinations thereof, and wherein the colloidal silica particles have a surface hydroxyl group density of from about 1.5 hydroxyls per nm2 to about 8 hydroxyls per nm2 of a surface area of the particles, (b) an anionic surfactant, (c) a buffering agent, and (d) water, wherein the polishing composition has a pH of about 2 to about 7, and wherein the polishing composition is substantially free of an oxidizing agent that oxidizes a metal. The invention further provides a method of chemically-mechanically polishing a substrate with the inventive chemical-mechanical polishing composition. Typically, the substrate contains silicon nitride, silicon oxide, and/or polysilicon.
US09803107B2 Polishing agent, polishing method and method for manufacturing semiconductor integrated circuit device
The present invention relates to a polishing agent including: cerium oxide particles; a water-soluble polyamine; potassium hydroxide; at least one selected from an organic acid and a salt thereof; and water, in which the polishing agent has a pH of 10 or more, a polishing method using the polishing agent, and a method for manufacturing a semiconductor integrated circuit device.
US09803104B2 Stereoscopic fabrics with special patterns and tactile texture produced by an eco-friendly non-dye formulation
The invention is related to a processing formulation and method for producing fabrics which are eco-friendly and easy to implement. The invention provides stereoscopic fabrics with special patterns and tactile texture produced by an eco-friendly non-dye formulation and process.
US09803103B2 Aqueous dispersion of a copolymer
An aqueous dispersion containing at least one copolymer, the copolymer being preparable by initially charging an aqueous dispersion of at least one polyurethane, and then polymerizing a mixture of olefinically unsaturated monomers in the presence of the polyurethane, where a water-soluble initiator is used, the metered addition of the olefinically unsaturated monomers is effected in such a way that a concentration of 6.0% by weight, based on the total amount of olefinically unsaturated monomers, in the reaction solution is not exceeded over the entire duration of the reaction, and the mixture of the olefinically unsaturated monomers contains at least one polyolefinically unsaturated monomer.
US09803100B2 Non-fluorinated water-based superhydrophobic surfaces
A superhydrophobic surface includes a substrate treated with a non-fluorinated composition, the composition including a hydrophobic component free of fluorine; a filler particle; and water, wherein the composition is at a pH greater than 7, and wherein the hydrophobic component is in an aqueous dispersion. The superhydrophobic surface alternatively includes a substrate treated with a non-fluorinated composition, the composition including a hydrophobic polymer free of fluorine; an exfoliated graphite filler particle including acid functional groups; water; and a stabilizing compound, wherein the composition is at a pH greater than 7, and wherein the hydrophobic polymer is in an aqueous dispersion.
US09803098B2 Conductive ink
Provided is a conductive ink including a conductive material and at least one benzoxazine-based compound. The conductive ink of the present invention can be easily formed into a thin film, is highly conductive after sintering, and has superior adhesion to various substrates. In addition, the use of the conductive ink according to the present invention facilitates the formation of a glossy, mirror-like metal thin film with high reflectance.
US09803094B2 Aqueous ink-jet inks containing mixtures of anionic and non-ionic polymeric binders
The present disclosure provides aqueous ink-jet inks having improved salt stability containing an aqueous vehicle, a colorant, and a mixture of a water-borne anionic polymeric binder and a water-borne non-ionic polymeric binder.
US09803092B2 Elastomeric body for vibration damping
An elastomeric body for vibration damping and/or suspension, has a base body and a flame-retarding coating which covers at least one section of the base body, wherein the flame-retarding coating has at least two intumescent fire protection systems and the first fire protection system contains expandable graphite which comprises at least a first fraction with an average grain size of more than 180 μm and at least a second fraction with an average grain size of less than 180 μm, and the second fire protection system forms a support structure in the expanded state, which structure at least partially fixes the expanded graphite in the expanded state.
US09803085B2 System and method for high throughput preparation of rubber-modified asphalt cement
This invention encompasses rubber modified asphalt cement compositions, as well as systems, apparatuses, methods for preparing, as well as methods for using rubber-modified asphalt cement compositions.
US09803081B2 Reinforced thermoplastic resin composition and molded article
A reinforced thermoplastic resin composition comprising specific amounts of: a main resin component (C) comprising 50 to 100% by weight of a polycarbonate resin (A) and 0 to 50% by weight of a graft copolymer (B) obtained by polymerizing an aromatic alkenyl compound monomer (a) and a vinyl cyanide compound monomer (b) in the presence of a rubber polymer (B1); a grass fiber (D); a glycidyl ether unit-containing polymer (E) containing glycidyl ether units and having a weight average molecular weight of 3,800 to 60,000; a phosphoric acid ester-based flame retardant (F); and an organomodified siloxane (G).
US09803077B2 Cast-molded article
A cast-molded article in a composite material comprising a cured polymeric binder incorporating embedded particles of filler, characterized in that the binder incorporates randomly distributed fibers of polyamide, wherein the fibers have a length of 5-20 mm and a diameter of 0.05-0.2 mm and the fibers comprise 0.02-0.5 wt % based on the overall mass of the cast-molded article.
US09803074B2 Polyolefin-based compositions, adhesives, and related multi-layered structures prepared therefrom
The present disclosure provides a polyolefin-based composition suitable for use as adhesives and/or tie-layer adhesive compositions as well as a multi-layered structure made from and/or containing the polyolefin-based composition. The polyolefin-based composition is made from and/or contains (a) a grafted polyolefin composition, (b) a first polymer composition, (c) a polypropylene-containing blend composition, and (d) optionally, an additives composition having one or more additives.
US09803073B2 Heat resistant ethylene vinyl acetate copolymer composition and process for its production
Disclosed herein are curable heat resistant ethylene vinyl acetate copolymer-polyamide blend compositions, wherein the ethylene vinyl acetate copolymer has a melting peak temperature of 100° C. or less. The blend compositions comprise 0.1 to 10 weight percent dispersed polyamide, and may be cured to form articles having improved heat resistance while maintaining the desirable physical properties of unmodified, cured ethylene vinyl acetate articles.
US09803070B2 Carboxylic acid modified-nitrile based copolymer latex for dip-forming, latex composition for dip-forming comprising the same, and product thereof
Disclosed are a carboxylic acid-modified nitrile copolymer latex for dip molding comprising a combination of a carboxylic acid-modified nitrile copolymer latex and a carboxylic acid-modified styrene copolymer latex, a latex composition for dip molding comprising the same and a molded article prepared therefrom. Molded articles with superior tensile strength are produced by respectively preparing a carboxylic acid-modified nitrile latex having a low glass transition temperature and an average particle diameter of 90 nm or higher, and a carboxylic acid-modified styrene latex having a glass transition temperature of 80° C. or higher and an average particle diameter less than 90 nm and then mixing the two latexes.
US09803068B2 Modeling compounds and methods of making and using the same
Modeling compounds and methods for making the same are described. The modeling compounds, in some embodiments, comprise about 20% to about 40% by weight starch-based binder, and about 0.15% to about 1.2% by weight microspheres dispersed throughout the compounds. In some embodiments, the modeling compound further comprises vinylpyrrolidone polymers.
US09803064B2 Colored resin particle dispersion and inkjet ink
A colored resin particle dispersion and an ink are provided which yield excellent abrasion resistance and prevent change in the color tone. Moreover, a colored resin particle dispersion and an inkjet ink are provided which exhibit excellent abrasion resistance, together with excellent water resistance and marker resistance. Specifically provided is a colored resin particle dispersion containing colored resin particles, a basic dispersant, and a non-aqueous solvent, wherein the colored resin particles include a colorant, a solid resin and a liquid organic compound having an acidic group, and the oxidation-reduction potential of the colored resin particle dispersion is 300 mV or less. Also provided is an inkjet ink containing this colored resin particle dispersion.
US09803061B2 Carbon fiber-reinforced thermoplastic resin composition, and pellets and molded article thereof
A carbon fiber-reinforced thermoplastic resin composition includes a thermoplastic resin (A), a carbon fiber (B), and a titanium compound (C), an amount of the thermoplastic resin (A) being 10 to 65% by weight, an amount of the carbon fiber (B) being 35 to 90% by weight, based on 100% by weight of the total amount of the thermoplastic resin (A) and the carbon fiber (B), and an amount of the titanium compound (C) being 0.01 to 5 parts by weight, based on 100 parts by weight of the total amount of the thermoplastic resin (A) and the carbon fiber (B).
US09803057B2 Method for preparing microporous polyolefin film by thermally-induced phase separation method
The present invention discloses a method for preparing a microporous polyolefin film comprising: a step of injecting a composition comprising polyolefin 30 to 60 wt % and a diluent mixture comprising a diluent, which can make liquid-liquid phase separation with the polyolefin thermodynamically 40 to 70 wt %, into an extruding machine, and melting and kneading thereof to prepare a single phase melt; and a step of extruding the melt while conducting liquid-liquid phase separation by passing through a section having the temperature below the liquid-liquid phase separation temperature and forming thereof in the form of a sheet, and a microporous polyolefin film prepared according to the method.
US09803056B2 Method of manufacturing crosslinked fluororesin powder
A method of manufacturing a crosslinked fluororesin powder includes forming a powder mixture by mixing a fluororesin powder as a first powder with a second powder not fusing to the fluororesin powder even under conditions for crosslinking of the fluororesin powder, and conducting a cross-linking treatment to the formed powder mixture.
US09803050B2 Dispersant for use in synthesis of polyaryletherketones
A method for forming a polyaryletherketone is described. More particularly, a reaction mixture is initially supplied to the reactor vessel that contains one or more precursor monomers. A heteroaryl compound is also added to the reaction mixture. The reaction can be carried out according to, e.g., an electrophilic aromatic substitution reaction or a nucleophilic aromatic substitution reaction. The heteroaryl compound can serve as a dispersant to the polymer as it is formed. This minimizes the likelihood of gelling of the product polymer within the reactor vessel and limits the impact of process disruptions on the production of the polyaryletherketone.
US09803044B2 Fluorine-containing oligomer, nano-silica composite particles using the same, and methods for producing both
Disclosed is a fluorine-containing oligomer comprising a copolymer of a fluoroalkyl alcohol (meth)acrylic acid derivative represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cOCOCR═CH2  [I] wherein R is a hydrogen atom or a methyl group, n is an integer of 1 to 6, a is an integer of 1 to 4; b is an integer of 0 to 3; and c is an integer of 1 to 3; and a (meth)acrylic acid derivative represented by the general formula: (CH2═CRCO)mR′  [II] wherein R is a hydrogen atom or a methyl group, m is 1, 2, or 3; and when m is 1, R′ is OH group, NH2 group that is unsubstituted or mono- or di-substituted with an alkyl group having 1 to 6 carbon atoms, or a monovalent group derived from an alkylene glycol or polyalkylene glycol group containing an alkylene group having 2 or 3 carbon atoms; when m is 2 or 3, R′ is a divalent or trivalent organic group derived from a diol or triol. The copolymerization reaction is performed using a hydrocarbon-based peroxide or azo compound polymerization initiator. Also disclosed are nano-silica composite particles formed as a condensate of the fluorine-containing oligomer and an alkoxysilane with nano-silica particles.
US09803042B2 Additive comprising low surface energy group and hydroxyl groups and coating compositions
Additives comprising a low surface energy group and one or more hydroxyl groups are described.
US09803039B2 Fluoropolyether-based elastomers having low glass transition temperature
A curable precursor composition for a fluoroelastomers, methods of making fluoroelastomers, shaped articles and methods of making shaped articles.
US09803036B2 Method for manufacturing fluoropolymers
The invention pertains to a process for manufacturing a (per)fluoropolymer, said process comprising polymerizing one or more fluorinated monomers in the presence of a multi-phase medium, said medium comprising: (A) a water phase [phase (W)]; (B) at least one fluorinated surfactant [surfactant (FS)] having formula (I) here below: Rf—(OCF2CF2)k-1—O—CF2—COOXa  (I) wherein Rf is a C1-C3 perfluoroalkyl group comprising, optionally, one or more ether oxygen atoms, k is 2 or 3 and Xa is a selected from a monovalent metal and an ammonium group of formula NRN4, wherein RN, equal or different at each occurrence, is a hydrogen atom or a C1-C3 alkyl group; (C) an oil phase [phase (O)] comprising: at least one non-functional (per)fluoropolyether (non-functional PFPE) comprising at least one (per)fluoropolyoxyalkylene chain [chain (RF)] and at least one functional (per)fluoropolyether (functional PFPE) comprising at least one (per)fluoropolyoxyalkylene chain [chain (R′F)] and having a number average molecular weight of at least 1000 and a solubility of less than 1% by weight in water at 25° C.
US09803026B2 Anti-human receptor-type protein tyrosine phosphatase sigma antibody
A monoclonal antibody that binds to an extracellular domain of human receptor-type protein tyrosine phosphatase σ (human PTPRS), or a fragment including an antigen-binding region thereof.
US09803022B2 Mesothelin domain-specific monoclonal antibodies and use thereof
Described herein is the use of rabbit hybridoma technology, along with a panel of truncated mesothelin domain fragments, to identify anti-mesothelin mAbs that bind specific regions of mesothelin. In one aspect of the present disclosure, the rabbit mAbs bind an epitope that is not part of Region I. In particular, the identified mAbs (YP187, YP223, YP218 and YP3) bind either Region II (391-486), Region III (487-581) or a native conformation of mesothelin with subnanomolar affinity. These antibodies do not compete for binding with the mesothelin-specific immunotoxin SS1P or mesothelin-specific antibody MORAb-009. In another aspect, disclosed is a high-affinity rabbit mAb that binds Region I of mesothelin (YP158). YP158 binds native mesothelin protein in cancer cells and tissues with high affinity and specificity.
US09803019B2 Carrier immunoglobulins and uses thereof
Disclosed is an isolated immunoglobulin. Also disclosed are pharmaceutical compositions and medicaments comprising the immunoglobulin, isolated nucleic acid encoding it, vectors, host cells, useful in methods of making it. In some embodiments the immunoglobulin comprises one to twenty-four pharmacologically active chemical moieties conjugated thereto, such as a pharmacologically active polypeptide.
US09803018B2 Amino acid sequences directed against cellular receptors for viruses and bacteria
The present invention relates to amino acid sequences that are directed against (as defined herein) human cellular receptors for viruses and/or bacteria such as e.g. Nanobodies specifically recognizing hCD4, hCXCR4, hCCR5, hTLR4, human alphaV integrin, human beta3 integrin, human beta1 integrin, human alpha2 integrin, hCD81, hSR-BI, hClaudin-1, hClaudin-6 and hClaudin-9, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. Amino acid sequences of the present invention may be used to prevent human cell entry of HIV, HCV, adenoviruses, hantavirus, herpesvirus, echo-virus 1 and others.
US09803016B2 Anti-CD47 antibodies and methods of use
Disclosed herein are anti-CD47 antibody molecules, their manufacture and use in treating disorders associated with CD47 expression, for example, certain hematological cancers and solid tumors.
US09803004B2 Albumin binding antibodies and binding fragments thereof
A serum albumin binding antibody or fragment thereof comprising a heavy chain variable domain having the sequence given in SEQ ID NO: 1 or SEQ ID NO:2 and/or comprising a light chain variable domain having the sequence given in SEQ ID NO:3 or SEQ ID NO:4, in particular comprising a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 1 and SEQ ID NO:3 or a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 2 and SEQ ID NO:4. The disclosure also extends to polynucleotides encoding the antibodies or fragments, vectors comprising same and host cells capable of expressing the polynucleotides. The disclosure further includes pharmaceutical compositions comprising the antibodies or fragments and therapeutic used of any one of the same.
US09803002B2 Anti-wall teichoic antibodies and conjugates
The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
US09803001B2 Monovalent, bivalent and trivalent anti human respiratory syncytial virus (hRSV) nanobody constructs for the prevention and/or treatment of respiratory tract infections
Amino acid sequences are provided that are directed against/and or that can specifically bind protein F of hRSV, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences, polypeptides and therapeutic compounds and compositions provided by the invention show an improved stability, less immunogenicity and/or improved affinity and/or avidity for protein F of hRSV.The invention also relates to the uses of such amino acid sequences, polypeptides, compounds or constructs for prophylactic and/or therapeutic purposes.
US09802994B2 Composition for preventing or treating fracture or osteoporosis using slit-robo system
A pharmaceutical composition for preventing or treating a fracture or osteoporosis, includes, as an active ingredient, a gene selected from a group consisting of slit1, slit2, slit3, robo1, robo2 and vilse, or an expressed protein of the gene. A marker composition for predicting the risk of the occurrence of a fracture or osteoporosis includes the protein. A kit for predicting the risk of the occurrence of a fracture or osteoporosis includes an antibody that specifically binds to the protein. An information provision method for predicting the risk of the occurrence of a fracture or osteoporosis includes measuring the level of expression of the slit protein through an antigen-antibody binding reaction using an antibody that specifically binds to the protein. The slit3 may increase bone formation and decrease bone reabsorption in a cellular and animal model, and has a negative correlation with the incidence rate of osteoporosis.
US09802993B2 Method for producing a cell for protein production by treating a cell overexpressing a taurine transporter with methotrexate
The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same. The present invention relates to a method for producing a cell capable of high-yield production of a desired polypeptide, wherein a strongly taurine transporter-expressing cell into which DNA encoding the desired polypeptide has been introduced is cultured in the presence of a high concentration of methotrexate and a cell capable of high-yield production of the desired polypeptide is selected from among surviving cells.
US09802989B2 Oil globule protein and uses thereof
An isolated novel oil globule protein encoded by a polynucleotide sequence is provided together with a composition which includes the isolated protein. A transgenic organism transformed by a polynucleotide encoding a protein which at least partially comprises the amino acid sequence of the novel oil globule protein is also provided. The invention also provides a method for producing or enhancing the production of a carotenoid such as astaxanthin, which is an oil globule constituent.
US09802987B2 Immunogenic fusion polypeptides
In one aspect, the invention relates to an isolated polypeptide including the amino acid sequence of a carrier polypeptide and the amino acid sequence of an ORF2086 polypeptide. In another aspect, the invention relates to an immunogenic conjugate including ORF2086 polypeptide and a carrier polypeptide. The invention further includes immunogenic compositions and methods for inducing an immune response against Neisseria meningitidis in a mammal.
US09802985B2 Pharmaceutical composition for treatment of the pulmonary form of altitude sickness caused by lack of oxygen and reduced air pressure
What is described is a peptide which consists of 7-20, especially 7-17, adjacent amino acids and comprises the hexamer TX1EX2X3E where X1, X2 and X3 may be any natural or unnatural amino acid, where the peptide does not have any TNF receptor binding activity and is cyclized, for use for the treatment and avoidance of the pulmonary form of altitude sickness.
US09802980B2 Method for producing pyrazoles, novel pyrazoles and applications thereof
A method for preparing a pyrazole of formula (I) in which R,R′ and R″ have different meanings, characterised in that it involves reacting a sydnone of formula (II) in which R and R′ have the meanings already indicated, with an alkyne of formula (III) in which R″ has the meaning already indicated, in the presence of copper, to obtain a pyrazole compound of formula (I) that is then isolated and salified if desired.
US09802978B2 Progesterone phosphate analogs and uses related thereto
This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
US09802971B2 Alkane dehydrogenation process
Disclosed herein are processes for dehydrogenation of an alkane to an alkene using an iridium pincer complex. In the dehydrogenation reactions, hydrogen that is co-formed during the process must be removed for the chemical reaction to proceed and to prevent the excess hydrogen from poisoning the catalyst. In one embodiment the process comprises providing an alkane feedstock comprising at least one alkane and contacting the alkane with an iridium pincer complex in the presence of a hydrogen acceptor selected from the group consisting of ethylene, propene, or mixtures to form an alkene product. The processes disclosed herein can accomplish facile, low-temperature transfer dehydrogenation of alkanes with unprecedented selectivities and TONs at a reasonable rate of conversion.
US09802969B2 Molecule for functionalizing a support, attachment of a radionuclide to the support and radionuclide generator for preparing the radionuclide, and preparation process
Molecule for attaching a radioactive parent nuclide to a support, comprising at least one functional group for attaching the radioactive parent nuclide; and a molecular moiety suitable for establishing a nonpolar bond to the support.
US09802968B2 Branched siloxanes and methods for synthesis
The present invention describes branched and functionalized siloxanes and methods for making such compounds. The compounds have a variety of uses. One preferred application is as novel planarizing material for lithogaphy, in which case functionalized branched siloxane, such as an epoxy-modified branched siloxane is particularly useful.
US09802959B2 Method of producing (4R,12aS)-7,9-dihalo-4-methyl-3,4,12,12a-tetrahydro-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-6,8-diones
A process for preparing a compound shown by formula (W5): wherein each Hal is independently chloro or bromo, using a novel process for preparing a pyridine derivative represented by formula (W2), wherein R6d is as defined herein.
US09802956B2 Spiroquinoxaline derivatives as inhibitors of non-apoptotic regulated cell-death
The present invention relates to compounds which are inhibitors of non-apoptotic regulated cell death, and to pharmaceutical compositions containing such compounds. Furthermore, the present invention relates to the use of such compounds and pharmaceutical compositions in therapy, in particular in the treatment of a condition, disorder or disease that is characterised by non-apoptotic regulated cell-death or where non-apoptotic regulated cell-death is likely to play or plays a substantial role. The compounds and pharmaceutical compositions described herein are also useful in the treatment of a condition, disorder or disease that is characterised by oxidative stress or where oxidative stress is likely to play or plays a substantial role; and/or a condition, disorder or disease that is characterised by activation of (1) one or more components of the necrosome; (2) death domain receptors; and/or (3) Toll-like receptors; and/or (4) players in ferroptotic/ferroptosis signalling, or where activation of any one of (1) to (3) and/or (4) is likely to play or plays a substantial role.
US09802955B2 Tricyclic compounds having antimitotic and/or antitumor activity and methods of use thereof
The present invention provides tricyclic compounds, pharmaceutically acceptable salts, prodrugs, solvates, or hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, for example P-glycoprotein inhibition, and antitumor activity, and which inhibit paclitaxel sensitive and resistant tumor cells. Also provided are methods of utilizing these compounds for treating tumor cells and inhibiting mitosis of cancerous cells.
US09802954B2 Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
Piperidino-dihydrothienopyrimidine sulfoxides of formula I wherein: Ring A is a 6-membered aromatic ring optionally comprising one or two nitrogen atoms and R is Cl and is located in the para-, meta-, or ortho-position of Ring A, S* is a sulphur atom that represents a chiral center, and all pharmaceutically acceptable salts, enantiomers and racemates, hydrates and solvates thereof and the use of these compounds for the treatment of inflammatory or allergic diseases of the respiratory tract such as COPD or asthma.
US09802950B2 Mono-ethers of isohexides and process for making the same
A method of making a mono-ether of an isohexide and art assemblage of novel. Song-chain isohexide mono-ethers are described. In particular, the method involves reacting an isohexide stereoisomer with a Bronsted base and an alkyl species. The resultant mono-ethers can serve as attractive antecedents or chemical scaffolds for making a derivative compound, such as various amphiphiles with potential uses as surfactants, dispersants, and lubricants, among others.
US09802949B2 Fused ring compounds as hepatitis C virus inhibitors, pharmaceutical compositions and uses thereof
Provided are fused tricyclic compounds effective to inhibit the function of the NS5A protein of formula (I), wherein X, X′, Y, Y′, A, A′, Q1, Q2, R1-R4, X4, R5a, f and W are defined as in the description. Also provided herein are pharmaceutical compositions thereof, and uses in the manufacture of a medicament for treating HCV infection or a HCV disorder thereof.
US09802946B2 NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
US09802945B2 Imidazopyridazine derivatives as modulators of the GABAA receptor activity
The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.
US09802937B2 Substituted pyrazolo{4,3-D}pyrimidines as kinase inhibitors
The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.
US09802935B2 CGRP receptor antagonists
The disclosures herein relate to novel compounds of formula wherein R1, R2 and R3 are as defined herein, and their use in treating, preventing, ameliorating, controlling or reducing cerebrovascular or vascular disorders associated with CGRP receptor function.
US09802933B2 Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described.
US09802927B2 Oxadiazine compounds and methods of use thereof
The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.
US09802920B2 Inhibitors of bruton's tyrosine kinase
This application discloses compounds according to generic Formula (I): wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are useful for the treatment of oncological, auto-immune, and inflammatory diseases caused by aberrant B-cell activation. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient.
US09802918B2 Pyridineamine compounds useful as Pim kinase inhibitors
The present disclosure describes pyridineamine compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
US09802917B2 Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
The present invention relates to particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, to a process of making said particles, to pharmaceutical compositions comprising said particles and to method of treating cancers using said pharmaceutical compositions.
US09802916B2 Indazole-3-carboxamides and their use as Wnt/beta-catenin signaling pathway inhibitors
Indazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole-3-carboxamide compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
US09802915B2 Indole carboxamide compounds
Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
US09802914B2 Antifungal compound process
The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 or 1a and substituted derivatives thereof.
US09802910B2 Method for preparing 5-hydroxymethyl-2-furfural using acid catalyst in presence of ethylene glycol-based compound solvent derived from biomass
Provided is a method for preparing 5-hydroxymethyl-2-furfural using an acid catalyst in the presence of an ethylene glycol-based solvent. The method for preparing the 5-hydroxymethyl-2-furfural involves using a linear or cyclic ethylene glycol-based compound as a solvent and producing the 5-hydroxymethyl-2-furfural from fructose, in the presence of the acid catalyst, thereby reducing the dependency on petroleum in response to greenhouse gas emission regulations. Also, a high yield of the 5-hydroxymethyl-2-furfural can be obtained from fructose, and the solvent and the catalyst can be efficiently separated, collected, and reused after a reaction has completed.
US09802908B2 Ethyl benzyl quaternary amines of amido amines for improved antifungal properties
Ethyl benzyl quaternaries having superior anti-fungal properties versus their benzyl quaternary analogs. The ethylbenzyl amidoamine quaternaries of the present invention are easily produced without significant waste and with minimal capital, while possessing improved antimicrobial properties.
US09802906B1 Process for the preparation of toltrazuril and an intermediate useful for its preparation
Disclosed is a process for the preparation of toltrazuril of formula (I) via the intermediate N-methyl-N′-[3-methyl-4-[4-[(trifluoromethyl)thio]phenoxy]phenyl] imidodicarbonic diamide of formula (III) wherein intermediate (III) is obtained via a novel intermediate without the use of potentially hazardous reagents or potentially unstable intermediates.
US09802905B2 Filtration process for purifying liquid azole heteroaromatic compound-containing mixtures
A process for removing impurities from a liquid azole heteroaromatic compound-containing (e.g., triazole-containing) mixture by: (a) providing a liquid azole heteroaromatic compound-containing mixture having impurities; and (b) passing the azole heteroaromatic compound-containing mixture through at least one filtration membrane which is a nanofiltration membrane and/or ultrafiltration membrane having a molecular pore size in the range of from about 200 daltons to about 1 kilodaltons to provide a permeate that is an at least partially purified azole heteroaromatic compound-containing mixture and a retentate with at least some impurities.
US09802904B2 Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof
Disclosed are inhibitors of the USP1/UAF1 deubiquitinase complex, for example. of formula (I), wherein R1, R2, and Q are as defined herein, which are useful in treating diseases such as cancer, and improving the efficacy of DNA damaging agents in cancer treatment. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention, a method of method of inhibiting a heterodimeric deubiquitinase complex in a cell, and a method of enhancing the chemotherapeutic treatment of cancer in a mammal undergoing treatment with an anti cancer agent. Further disclosed is a method of preparing compounds of the invention.
US09802902B2 Antifungal compound
There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by hydrophobic linkers selected to confer a therapeutic effect. There is also provided the use of the above compound in the manufacture of a medicament for the treatment of a fungal infection and a method of treating a fungal infection using the above compound.
US09802900B2 Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
US09802899B2 Heterocyclic compounds as pesticides
The present application relates to the use of heterocyclic compounds for controlling animal pests including arthropods, insects and nematodes, to novel heterocyclic compounds, to processes for their preparation and to intermediates for preparing the heterocyclic compounds.
US09802897B2 Amidopyridinol derivative or pharmaceutically acceptable salt thereof and pharmaceutical composition comprising same as active component
An amidopyridinol derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition including the amidopyridinol derivative as an active component represented by Chemical Formula 1 or a pharmaceutically acceptable salt thereof have an antiangiogenic effect in a chorioallantoic membrane model, and thus are useful as an agent for preventing or treating diseases associated with angiogenesis, and also have a colitis-inhibitory effect in a model of inflammatory bowel diseases, and thus are useful as an agent for preventing or treating inflammatory bowel diseases. Upon inoculation of lung cancer cells in a chorioallantoic membrane model, the amidopyridinol derivative of Chemical Formula 1 or the pharmaceutically acceptable salt thereof inhibits angiogenesis and tumor growth that are caused by tumorigenesis, and also inhibits the activity of cathepsin S that plays an important role in metastasis and invasion of cancer, and thus is useful as an inhibitor of cancer growth and metastasis.
US09802892B2 Method for stepwise separating amino acid active ingredients of Camellia nitidissima Chi
The present invention relates to the technical field of Camellia nitidissima Chi processing and application, and provides a method for stepwise separating amino acid active ingredients of Camellia nitidissima Chi. The method comprises the following steps: taking a graphene nano material as a selective extraction, adsorption and separation carrier material; carrying out stepwise separation through stepwise controlling the pH value of Camellia nitidissima Chi concentrated solution and adjusting the isoelectric points of the amino acid active ingredients, wherein the amino acid active ingredients comprise aspartic acid, threonine, serine, glutamic acid, proline and glycine, and the pH values of the aspartic acid, the threonine, the serine, the glutamic acid, the proline and the glycine corresponding to the stepwise separated isoelectric points are less than 2.77, 5.98-6.15, 3.23-5.67, 2.78-3.21, 6.17-6.29 and 5.69-5.96. The method for stepwise separating amino acid active ingredients of Camellia nitidissima Chi has the characteristics of superior selectivity, superior separation speed, good product purity and low cost.
US09802888B2 STAT3 inhibitors
The present disclosure provides pharmaceutical compositions comprising Stat3 inhibitors and certain pharmaceutically acceptable salts thereof, and methods of use.
US09802887B2 Process for the preparation of intermediates useful for the manufacture NEP inhibitors
The invention relates to a new process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone, such as N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
US09802882B2 Method for chromatographic purification of a fatty acid
The invention related to a method for purifying a first fatty acid, preferably polyunsaturated, using an initial mixture further comprising at least one second fatty acid, optionally a third fatty acid and optionally a fourth fatty acid, with the method comprising: a first step of chromatographic separation in liquid phase, using the initial mixture, carried out in a first unit for chromatographic separation, making it possible to recover on the one hand a first flow enriched with a first fatty acid and on the other hand a flow enriched with a second fatty acid, optionally, a second step of chromatographic separation in liquid phase, using the first flow enriched with a first fatty acid, carried out in a second chromatographic separation unit, making it possible to recover on the one hand a second flow enriched with a first fatty acid and on the other hand a flow enriched with a third fatty acid; optionally, a third step of chromatographic separation in liquid phase, using the third flow enriched with a first fatty acid, carried out in a third chromatographic separation unit, making it possible to recover on the one hand a third flow enriched with a first fatty acid and on the other hand a flow enriched with a fourth fatty acid; at least one among the first unit for chromatographic separation, the second unit for chromatographic separation and the third unit for chromatographic separation being a static bed chromatographic separation unit with a single column with recycling in stationary state.
US09802873B1 Methods for the production of renewable Dimethyl JP10
A highly efficient method for the conversion of a natural product into the high density fuel RJ-4 with concomitant evolution of isobutylene for conversion to fuels and polymers, more specifically, embodiments of the invention relate to efficient methods for the conversion of the renewable, linear terpene alcohol, linalool into a drop-in, high density fuel suitable for ramjet or missile propulsion.
US09802870B2 Method of treating ceramic fibers by phosphating
A method of treating silicon carbide fibers comprises phosphating heat treatment in a reactive gas so as to form a coating around each fiber for protection against oxidation. The coating comprises a surface layer of silicon pyrophosphate crystals and at least one underlying bilayer system comprising a layer of a phosphosilicate glass and a layer of microporous carbon.
US09802863B1 Accelerating set times of flowable fill compositions with dry calcium chloride, and methods of utilizing and producing the same
Fast-setting Portland cement compositions for filling voids, such as mine shafts and excavated utility trenches, are described. The Portland cement compositions set quickly and are useful when traditional slow setting compositions are less desirable. The acceleration of the set time results from the addition of dry calcium chloride to the Portland cement composition. The compositions consist of Portland cement, dry calcium chloride, water and sometimes preformed cellular foam. Some compositions can include also include fly ash. The compositions may have a compressive strength of between 0 psi and 30 psi after 4 hours, a compressive strength of between 30 psi and 120 psi after 24 hours, a compressive strength of between 200 psi and 500 psi after 28 days, a penetration resistance of between 0.1 tsf and 5 tsf after 10 hours, a penetration resistance of between 0.8 tsf and 10 tsf after 24 hours, and a removability modulus of between 0.2 and 1.0 after 28 days. Also disclosed are methods of filling a void with fast-setting Portland cement.
US09802862B2 CO2 emission-free construction material made of CO2
Building materials and methods of making a building material are disclosed. An exemplary method includes receiving algae; and subjecting the algae to an oil extraction process, in order to produce vegetable oil. The method further includes producing synthetic fibers by processing the vegetable oil from the oil extraction process; and processing the synthetic fibers to produce a tension and pressure resistant material.
US09802861B2 Process for the preparation of cement, mortars, concrete compositions containing a calcium carbonate-based filler treated with an ultrafine filler and a superplastifier, compositions and cement products obtained and their applications
Process for the preparation of cement/mortar/concrete compositions or systems, (for simplicity hereafter “cement” compositions or systems or even “cements”), of a generally known type containing low or medium (standard) “filler(s)”, and/or optionally HP filler(s), as carbonate-based filler(s), namely coarse low or medium calcium carbonate(s), namely coarse marble(s); Product comprising, or consisting of, the pre-blend (A) of coarse, low or medium (or optionally HP) “calcium carbonate-based filler” pre-blended with at least an UF; Aqueous compositions (B) obtained by mixing the above pre-blend (A) of coarse filler(s) with UF(s) with an aqueous system such as mix water, aqueous mix fluid; Product (C) consisting of, or comprising, the pre-blend (A) or the compositions (B), treated or pretreated with at least one superplastifier or aqueous system containing superplastifier(s); Cement and Use of cement.
US09802858B2 Low loss optical fibers with fluorine and chlorine codoped core regions
A co-doped optical fiber is provided having an attenuation of less than about 0.17 dB/km at a wavelength of 1550 nm. The fiber includes a core region in the fiber having a graded refractive index profile with an alpha of greater than 5. The fiber also includes a first cladding region in the fiber that surrounds the core region. Further, the core region has an relative refractive index of about −0.10% to about +0.05% compared to pure silica. In addition, the core region includes silica that is co-doped with chlorine at about 1.2% or greater by weight and fluorine between about 0.1% and about 1% by weight.
US09802853B2 Fictive temperature in damage-resistant glass having improved mechanical characteristics
A strengthened glass sheet product as well as process and an apparatus for making the product. The process comprises cooling the glass sheet by non-contact thermal conduction for sufficiently long to fix a surface compression and central tension of the sheet. The process results in thermally strengthened glass sheets having improved breakage properties.
US09802851B2 Overflow downdraw glass forming method and apparatus
The present invention discloses improved methods and apparatus for forming sheet glass. In one embodiment, the invention introduces a counteracting force to the stresses on the forming structure in a manner such that the thermal creep which inevitably occurs has a minimum impact on the glass flow characteristics of the forming structure.
US09802846B2 Treating and recylcing oilfield waste water
A process for treating oilfield waste water includes combining oilfield waste water and a biocide comprising hydrogen peroxide, the biocide being present in an amount effective to decrease a number density of bacteria in the oilfield waste water. The treated water can be reused in a subterranean environment.
US09802843B2 Water quality-upgrading device
A water quality-upgrading device includes a container having an inner peripheral wall defining a receiving chamber and two opposite ends respectively defining an inlet and an outlet; at least two water molecule refinement layers disposed in the receiving chamber; two filtering sheets disposed at said inlet and said outlet of the container respectively; and wherein, when water flows into said receiving chamber, the water molecule refinement layers are capable of reducing dimension of water molecules so as to spread the finer water molecules on an oil sludge stained on a substance such that the finer water molecules penetrate into gaps formed between the oil sludge and an external surface of the substance, thereby reducing contact area amount and simultaneously weakening a bonding property between the oil sludge and the external surface of the substance to facilitate removal of the oil sludge off the substance by of a wiping cloth.
US09802833B2 Synthesis of metal oxide-based thermoelectric materials for high temperature applications
Nanowire synthesis and one dimensional nanowire synthesis of titanates and cobaltates. Exemplary titanates and cobaltates that are fabricated and discussed include, without limitation, strontium titanate (SrTiO3), barium titanate (BaTiO3), lead titanate (PbTiO3), calcium cobaltate (Ca3Co4O9) and sodium cobaltate (NaCo2O4).
US09802831B2 Synthesis of high silica zeolite via interzeolite transformation without OSDAs
Provided is a method for preparing a zeolite having a Si/Al ratio of at least 10 by interzeolite transformation in the absence of an organic structure directing agent. The method is more cost effective and less equipment intensive as it eliminates the costly organic structure directing agent and the waste treatment at the plant.
US09802830B2 Molecular sieve SSZ-91
A family of new crystalline molecular sieves designated SSZ-91 is disclosed. Molecular sieve SSZ-91 is structurally similar to sieves falling within the ZSM-48 family of molecular sieves, and is characterized as: (1) having a low degree of faulting, (2) a low aspect ratio that inhibits hydrocracking as compared to conventional ZSM-48 materials having an aspect ratio of greater than 8, and (3) is substantially phase pure.
US09802824B2 Granular activated carbon, and manufacturing method for same
Provided is a granular activated carbon that can be used for applications similar to wood-based steam-activated carbons; and also provided is a method for manufacturing the same. The granular activated carbon is obtained in the following manner. An activated carbon raw material is carbonized, and then pulverized. The pulverized product is then mixed with a calcium component, and the mixture is molded. Subsequently, the molded product is carbonized and activated, followed by washing.
US09802818B2 Sorting process of nanoparticles and applications of same
In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
US09802817B2 Method for making suspended elements with different thicknesses for a MEMS and NEMS structure
Method for making a N/MEMS device including a structure provided with an active part having a first suspended element and a second suspended element with different thicknesses, the method comprising the following steps of: forming, in a first substrate (100), a sacrificial zone (105), transferring a given layer onto the sacrificial zone, defining in said given layer a first suspended element facing the first sacrificial zone, defining a second suspended element in the first substrate and said given layer, releasing at least the first suspended element.
US09802815B2 Method for MEMS structure with dual-level structural layer and acoustic port
A method for fabricating a MEMS device includes depositing and patterning a first sacrificial layer onto a silicon substrate, the first sacrificial layer being partially removed leaving a first remaining oxide. Further, the method includes depositing a conductive structure layer onto the silicon substrate, the conductive structure layer making physical contact with at least a portion of the silicon substrate. Further, a second sacrificial layer is formed on top of the conductive structure layer. Patterning and etching of the silicon substrate is performed stopping at the second sacrificial layer. Additionally, the MEMS substrate is bonded to a CMOS wafer, the CMOS wafer having formed thereupon a metal layer. An electrical connection is formed between the MEMS substrate and the metal layer.
US09802811B2 Fluid dispensing system and method of heating in a fluid dispensing system
A dispensing system is provided for heating a fluid in the dispensing system. A method for heating a fluid in a dispensing system is also provided.
US09802810B2 Blending apparatus and method
A method of delivering a selected fuel product having a selected octane level to an operator from a fuel dispenser including a blend manifold, a fuel nozzle, and a fuel hose extending therebetween, including the steps of determining a first volume of a first fuel that is retained in the fuel hose upon completion of a first fueling event, determining a first octane level of the first volume of the first fuel, determining a second volume of a second fuel having a second octane level, and delivering the first fuel volume and the second fuel volume to the operator during a second fueling event, wherein a total volume of fuel equaling the first volume of the first fuel and the second volume of the second fuel has a total octane level that falls within a predetermined limit of the selected octane level of the selected fuel product.
US09802807B2 Apparatus and method for pressure dispensing of high viscosity liquid-containing materials
A liner-based pressure dispensing container includes a connector-mounted probe arranged to seat a dip tube against an inner surface of a liner fitment for sealing utility. A dip tube and probe may include increased and/or matched flow area. A reverse flow prevention element can be arranged proximate to a liquid extraction opening to inhibit reverse flow of liquid from a dip tube into a container. A liner-less container may include a reduce diameter lower portion arranged to receive a dip tube, with at least one associated sensor to sense a condition indicative of depletion of liquid from the lower portion. A shipping cap can be included for removing headspace gas from the liner. In one embodiment, the shipping cap is suitable for direct connection to a dispensing process.
US09802802B2 Work tool
A work tool for a machine is provided including a laminated member having a plurality of layers of plates. Each plate is arranged in parallel to the other plates and has a face in contacting relation with an opposing face of an adjacent plate. Adjacent plates are secured together by welds along only a portion of an exterior surface of the laminated member. A plurality of pins hold together the plurality of layers of plates. Each pin is received in a respective opening that extends through each plate in the plurality of layers between opposing first and second surfaces of the laminated member.
US09802780B2 Apparatus for collecting sheets and apparatus for forming images
Provided is an apparatus provided with a collection tray for receiving a discharged sheet and shifting, a discharge unit (binding unit constituting a part of a sheet processing apparatus) for discharging a sheet, a shift rail (up-and-down rail including an up-and-down rack) provided in the discharge unit to permit a shift of the collection tray corresponding to a sheet collection amount of the collection tray, a drive member (up-and-down motor) that shifts the collection tray along the shift rail, and an extension rail capable of being added and set onto the shift rail to extend a shift range of the collection tray. By this means, it is possible to increase a collection amount of sheets relatively with ease.
US09802779B2 Methods and systems for preventing wrinkles in a web fed through an accumulator
Methods and systems for preventing wrinkles in a web passing through an accumulator. The accumulator comprises a plurality of rollers including at least one roller having an axis of revolution movable toward and away from the axis of revolution of another roller to release and store varying amounts of the web. At least one of the rollers has a nominally flat outer surface and at least one of the rollers has a profiled outer surface.
US09802777B2 Belt conveyor system comprising a mesh belt and a sheet conveyor system for conveying sheets in a reprographic apparatus
Belt conveyor system comprising: an endless mesh belt, the belt having a mesh structure and having edge areas at the lateral sides, a drive mechanism drivable by a drive motor to rotate the belt, and a steering roller for steering the lateral position of the belt, wherein an edge area comprises a band running substantially parallel to the lateral sides, the band comprising an elastic filler being provided inside the mesh structure, the elastic filler being discernible from the mesh structure, and wherein the belt conveyor system further comprises a band position detector for detecting the lateral position of the band.
US09802775B2 Sheet separating device, sheet supplying device, and image forming apparatus
A sheet separating device includes: a lifting nozzle configured to blow air against an end portion of a sheet bundle placed on a sheet loading portion to lift sheets; a separating nozzle configured to separate the sheets; a lifting-nozzle shutter member configured to open and close the lifting nozzle; a separating-nozzle shutter member configured to open and close the separating nozzle; a lifting-shutter driving mechanism configured to drive the lifting-nozzle shutter member; a separating-shutter driving mechanism configured to drive the separating-nozzle shutter member; and an open/close control unit configured to control the lifting-shutter driving mechanism and the separating-shutter driving mechanism such that the lifting-nozzle shutter member and the separating-nozzle shutter member are opened or closed simultaneously.
US09802773B2 Sheet conveyor and image reader
A sheet conveyor includes: a chute which has openings spaced apart from each other in a first direction and guides a sheet; a drive shaft; drive rollers mounted on the drive shaft and each partly protruding from the chute through a corresponding one of the openings; driven rollers each urged and contactable with a corresponding one of the drive rollers; an intermediate bearing disposed at a first position located between adjacent two of the drive rollers; and a holder provided on the chute to hold the intermediate bearing located at the first position. The intermediate bearing is in contact with an outer circumferential surface of the drive shaft when located at a second position different from the first position. The intermediate bearing is slid from the second position to the first position in the first direction and held by the holder at the first position.
US09802764B1 Remotely operated hydraulic system
A remotely operated hydraulic system is configured to engage an unloader in a semi-trailer. The remotely operated hydraulic system includes a solenoid mechanically coupled to the semi-trailer. The solenoid is further mechanically coupled to at least one air input line and at least one air output line. A receiver is electrically coupled to the solenoid and communicatively coupled to a remote control. The receiver is configured to open and close the solenoid based on a signal from the remote control. An air cylinder is mechanically coupled to the at least one air output line and a manual valve. Receiving air into the air cylinder operates to open the manual valve. A motor is mechanically coupled to the air cylinder and the unloader; wherein hydraulic pressure from the manual valve is configured to turn the motor and thus the unloader.
US09802761B2 Automated storage and retrieval system
An autonomous rover including a frame having a first end and a second end longitudinally spaced from the first end and forming a payload bay, the payload bay being sized to support a pickface, a common active registration surface configured to engage the pickface, and a drive section connected to the common active registration surface, the drive section being configured to variably position the common active registration surface relative to at least one storage shelf of an automated storage and retrieval system to effect placement of the pickface on the storage shelf so that pickfaces are substantially continuously arranged along the at least one storage shelf with a predetermined storage spacing between the pickfaces.
US09802760B2 Automated warehouse and method for controlling automated warehouse
In an automated warehouse, if a controller receives an instruction to retreat a first carrier and if the first carrier is holding an article or if an article is housed in a housing shelf corresponding to an isolation region that is a retreat destination, the controller causes the first carrier to carry the article to a housing shelf to and from which a second carrier is able to transfer an article, then causes the first carrier to retreat, and then drives the second carrier within a range of a track except for the isolation region. When it is detected that one of first doors corresponding to the isolation region has been opened, the controller continues driving the second carrier.
US09802756B2 Cassette for dispensing pleated tubing
A cassette for use in dispensing a pleated tubing within a waste container. The cassette including an annular body having a generally U shaped housing with a central cylindrical core. An annular cover extends inward over the annular body defining a gap. The cover is secured to the body and at least one elongated boss is disposed on an outer surface of the cassette. The elongated boss extends is adapted to receive a key element capable of rotating, or preventing rotation of the cassette.
US09802752B2 Shroud and dispensing system for a handheld container
A dispensing system includes a manifold adapted to be fluidly coupled to a valve stem of a container. The manifold includes first and second members extending outwardly from the manifold. The dispensing system also includes a shroud having first and second shroud portions on opposing sides of the shroud. The dispensing system further includes at least one enclosed track. The enclosed track receives and permits sliding of at least one of the first and second members.
US09802749B2 Liner-based liquid storage and dispensing systems with empty detection capability
Fluid supply systems for storage and dispensing of chemical reagents and compositions, e.g., high purity liquid reagents and chemical mechanical polishing compositions used to manufacture microelectronic device products, having capability for detection of an empty or near-empty condition when the contained liquid is at or approaching depletion during dispensing operation. Fluid delivery systems employing empty detect arrangements are described, including pressure transducer monitoring of dispensed material intermediate the supply package and a servo-hydraulic dispense pump, or monitoring of dispenser chamber replenishment times in a dispenser being replenished on a cyclic schedule to flow material from the dispenser to a downstream tool utilizing the dispensed material.
US09802744B2 Re-sealable packages with independently peelable lidding member portions
Improved packages and methods for constructing packages are provided that are designed such that the user can peel back a lidding member of the package to reveal an independently peelable portion covering one of the compartments. The independently peelable portion is a layer of the lidding member that maintains the respective compartment in an unopened (sealed) condition until the user independently peels that layer off to access the items in that compartment. The lidding member can be used to re-seal all of the compartments before and/or after the independently peelable portion is removed. The independently peelable portion may include a visual indication of a sealed condition of the compartment that serves as a tamper evidence feature. In multiple-compartment packages, peeling back the lidding member allows the user to access some of the compartments of the package, while at least one of the compartments remains sealed via the independently peelable portion.
US09802742B1 Elastic fastener and method of use
A fastener has an elastic body that extends to opposed ends, and a three dimensional sphere-like head connected to each of the ends of the elastic body. A plurality of apertures are formed through the elastic body, sized to enable one of the three dimensional sphere-like heads to be pushed through the aperture for securing the fastener. The fastener may be wrapped around two elements, and the head or heads may each be inserted through one of the apertures so that the fastener secures the two elements together.
US09802736B2 Fastening device for sealing a fluid product reservoir
A fastener device for closing a fluid reservoir (1) formed with a neck (10) provided with outer peripheral reinforcement (11) that co-operates with the remainder of the neck to define a bottom shoulder (12). The device includes a fastener ring (2) for holding a closure member (4) on the neck (10), the fastener ring (2) including a peripheral skirt (21) engaged around the neck to below the bottom shoulder (12). The skirt (21) has fastener elements (26a, 26b) that form a contact zones (27a, 27b) suitable for potentially engaging the neck (10) below the bottom shoulder (12). The contact zones (27a, 27b) are situated at different axial heights, such that some contact zones (27a; 27b) come into operating engagement below the bottom shoulder (12), while other contact zones (27a; 27b) remain inoperative.
US09802735B2 Lid having circumferential rim with plurality of ribs
A lid for securing to the brim of a container, the lid including a container closure having a disk shaped member with a periphery for mating with the brim of the container. The periphery includes annular inner and outer side walls with at least one annular rib disposed on each of the inner and outer side walls. The ribs of the annular walls form a gripping area to secure the lid to the container for preventing leaks and accidental spillage. A top wall interconnects the inner and outer side walls and includes visual cues for viewing the brim of the container when the lid is affixed to the brim. The lid additionally includes a pronounced wedge shaped sipping spout projecting upwards from the container closure. The container closure includes a circular indented channel for stacking one lid covered cup over another with additional stability provided by the sipping spout.
US09802729B2 Blow molding method, blow mold, and blow-molded container
A blow molding method includes a primary blow molding step that molds a preform (200) in a primary blow mold (300A) that includes a primary temperature control section (330) to obtain an intermediate molded article (202), a shrinkage step that discharges blow air from the intermediate molded article to shrink the intermediate molded article, and a secondary blow molding step that blow-molds the intermediate molded article (204) that has shrunken in a secondary blow mold that includes a secondary temperature control section (430) to obtain a final molded article. The primary blow molding step cools a first intermediate molding region of the intermediate molded article that follows a neck using a first primary temperature control section, and the shrinkage step shrinks a second intermediate molding region of the intermediate molded article of which the temperature is controlled by a second primary temperature control section.
US09802723B2 Corner post application system
A corner post application system comprises a conveyor subsystem and an enveloping machine adapted to envelope the plurality of units with a material. The system further includes a swing arm, an applicator arm coupled to the swing arm and adapted to move linearly, a corner post gripper coupled to the applicator arm, and a controller. The controller rotates the swing arm about a vertical axis until a corner post held by the corner post gripper is aligned with adjacent sides that define a corner of the load. The controller thereafter stops rotation of the swing arm and moves the applicator arm linearly toward the corner of the load until the corner post held by the corner post gripper contacts the adjacent sides of the load. A sensor may be included for detecting a corner of the load, with the controller aligning the corner post based on detection by the sensor.
US09802712B2 Quick release system for a coupling and drogue assembly
The invention refers to a quick released system for coupling (1) and drogue (2) assembly comprises a crown coupling connector (4) suitable for being fixed to the coupling (1) and comprising cavities (14); a plurality of balls (3) housed in the cavities (14) with an emerging part and radially movable; a crown drogue connector (5) suitable for being fixed to the drogue (2), configured to engage and disengage the coupling connector (4) and comprising first recesses (26); and a crown locking ring (6) rotatable between a locked and a released position and comprising second recesses (31). The second recesses (31) are arranged in correspondence with the first recesses (26) when the system is in a released position and, the locking ring (6) in contact with the balls (3) and the first recesses (26) engaged with the emerging part of the balls (3) when the system is in a locked position.
US09802711B2 Multi-layer de-icing skin for aircraft platforms
An ice resistant structure is provided which includes a self-supporting, structural platform, a retaining, protective layer and a subsurface anti-icing (AI) and/or de-icing (DI) layer. The retaining, protective layer is disposed over the self-supporting, structural platform. The subsurface anti-icing (AI) and/or de-icing (DI) layer is located between the self-supporting, structural platform and the retaining, protective layer. The subsurface Al and/or DI layer is a functional layer such that an Al and/or DI agent is released to a surface of the retaining protective layer by an activation mechanism responsive to a change in an environmental condition.
US09802708B2 Aircraft low clearance fluid check valve
A fluid check valve for use in an aircraft fluid handling system having a confined surrounding structure where a first distance is defined between a fluid duct and the surrounding structure where the design of the fluid check valve is configured to facilitate removal of a first flange and the flow duct by moving the first flange and flow duct a second distance that is less than the first distance. The check valve is offset into the upstream side of a second flange to provide the reduction in the distance that the first flange has to be displaced to remove the first flange and flow duct from the check valve. A first alternate configuration of the fluid check valve utilizes rotational stops attached to the downstream surface of the flow flaps and in a second alternate embodiment configuration, rotational stops extend upstream from the flow flaps.
US09802703B2 Galley compartment for a galley system of an aircraft
A galley system includes a galley compartment defining a cavity. The galley compartment has a door that allows access to the cavity and at least a first opening and a second opening. A galley cart is positionable in the cavity of the galley compartment that has a first opening and a second opening. An air supply duct is configured to be coupled in flow communication with the first opening of the galley cart and the first opening of the galley compartment. A space is defined about the galley cart when the galley cart is positioned in the cavity. The space provides flow communication between the second opening of the galley cart and the second opening of the galley compartment.
US09802702B1 Unmanned aerial vehicle motor driving randomization for noise abatement
This disclosure is directed to varying a speed of one or more motors in an unmanned aerial vehicle (UAV) to reduce unwanted sound (i.e., noise) of the UAV. A UAV may include motors coupled with propellers to provide lift and propulsion to the UAV in various stages of flight, such as while ascending, descending, hovering, or transiting. The motors and propellers may generate noise, which may include a number of noise components such as tonal noise (e.g., a whining noise such as a whistle of a kettle at full boil) and broadband noise (e.g., a complex mixture of sounds of different frequencies, such as the sound of ocean surf). By varying the controls to the motors, such as by varying the speed or revolutions per minute (RPM) of a motor during operation by providing random or pseudo-random RPM variations, the UAV may generate a noise signature with reduced tonal noise.
US09802701B1 Variable elevation signal acquisition and data collection system and method
The disclosure herein relates to the use of unmanned aerial vehicles (UAVs) to detect and map electromagnetic transmission and reception patterns for transmitting facilities such as cell towers and receiving facilities such as large buildings in urban areas. A variable elevation signal acquisition and data collection (VESAD) system is provided that includes an unmanned aerial vehicle (UAV) including a guidance subsystem, a data storage device, a global positioning system (GPS), an electromagnetic signal detector, a radio frequency receiver, at least one antenna and a signal processing subsystem are in operable communication. A ground control station is also included that is configured to exercise positive wireless control over the UAV via the at least one antenna and guidance subsystem. A communications link between the UAV and the remote control system configured to communicate data received from one of the signal processing subsystem in real time and the data storage device.
US09802699B2 Adaptively-twistable blade, and an aircraft including such a blade
A blade (1) having an outer covering (2) defining a cavity (8). A carriage (20) is arranged in said cavity (8), the carriage (20) being provided with a torsion bar (21) and at least two arms (22) secured to the torsion bar (21). The blade has one connection per arm provided both with an upstream guide gallery and with a downstream guide gallery, each arm extending transversely from an upstream end that slides in an upstream guide gallery to a downstream end that slides in a downstream guide gallery. At least one connection is a helical connection (40) obtained with the help of an upstream guide gallery (33) and the downstream guide gallery (34) of the segment (101) presenting distinct orientations, giving rise to movement in rotation (ROT1) of the segment (101) under the effect of the carriage (20) moving in translation.
US09802696B2 Method and apparatus for control of a steerable landing gear
A slip-reduction control unit for an aircraft having a steerable landing gear. The control unit receives steering input signals from which a target steering command output may be ascertained and additional input signals (a) the motion of the aircraft, (b) a steering angle, or (c) a parameter relating to the slip sustained by the steerable landing gear. The slip-reduction control unit determines, based on the additional input signals, reduces the rate of change of steering angle that would otherwise be commanded. The reduction in the rate of change may reduce vibration on the aircraft that might be caused by a greater rate of change in the steering angle.
US09802690B2 Cargo airship
A cargo airship is disclosed. The cargo airship may include a hull configured to contain a gas and at least one propulsion assembly coupled to the airship and including a propulsion device. The cargo airship may further include a payload bay comprising an external cargo area located outside of the hull. The cargo airship may also include a cargo handling system including at least one hoisting mechanism configured to lift cargo into the external cargo area while the airship is hovering.
US09802689B2 Oil collection system
An oil collection system includes a boat that has an engine. A pan is removably coupled to the engine such that the pan may capture oil leaked from the engine. A plurality of clips is provided and each of the clips is coupled to the pan. Each of the clips engages the bottom end of the engine such that the pan is removably retained on the engine. A filter is positioned within the pan such that the filter filters the oil. A gauge is coupled to the pan such that the gauge may display an amount of oil contained within the pan. A drain is coupled to the pan such that the drain may selectively drain the oil from the pan.
US09802688B1 Systems and methods for mounting a propulsion device with respect to a marine vessel
A system comprises an elastic mount configured to support a propulsion device with respect to a marine vessel. The elastic mount contains an electromagnetic fluid. An electromagnet is configured so that increasing an amount of electricity applied to the electromagnet increases the shear strength of the electromagnetic fluid in the elastic mount and thereby decreases elasticity of the elastic mount, and so that decreasing the amount of electricity applied to the electromagnet decreases the shear strength of the electromagnetic fluid in the elastic mount and thereby increases the elasticity of the elastic mount. A controller automatically adapts the amount of electricity applied to the electromagnet during translation of the marine vessel so as to reduce the likelihood that the propulsion device impacts an adjacent structure on the marine.
US09802686B2 Sailboat accessory paddle head
The present application relates to an accessory paddle head for use with a spinnaker pole. The accessory paddle head is adapted to releasably connect to a spinnaker pole to provide a paddle system. The accessory paddle head surface optionally includes gripping members disposed on its surface for engaging with and detachably securing the spinnaker pole. The accessory paddle head is optionally formed of molded material.
US09802684B2 Wake-modifying device for a boat
A recreational sport boat includes a hull having starboard and port sides and a transom, a generally horizontal platform, and a pair of wake-modifying devices positioned aft of the transom. The generally horizontal platform extends aft of the transom and is configured to support a human weighing at least 100 lbs. on an upper surface thereof. The pair of wake-modifying devices are attached to the platform. One of the wake-modifying devices is positioned on a port side of the platform's centerline, and another of the wake-modifying devices is positioned on a starboard side of the platform's centerline. Each wake-modifying device is moveable between a non-deployed position and a deployed position in which the wake-modifying device is angled downwardly at an angle relative to the top surface of the generally horizontal platform.
US09802683B2 Sandglass type ocean engineering floating structure
A sandglass type ocean engineering floating structure is provided with an upper structural body shaped as a circular truncated cone or frustum and a lower structural body shaped as a regular circular truncated cone or regular frustum; under a combined state, the smaller bottom surface of the upper structural body is fixedly connected with the smaller bottom surface of the lower structural body to form a junction surface; the axis of the upper structural body and the axis of the lower structural body are positioned on the same straight line; the larger bottom of the upper structural body acts as an upper deck of the floating structure and the larger bottom of the lower structural body acts as a lower plate underwater of the floating structure; the junction surface is a full-load waterplane of the floating structure.
US09802675B1 Exhaust trim tab for a boat
A moveable exhaust trim tab for a motorized boat directs exhaust gas and cooling liquid into the water, changing the size and shape of the wake and reducing engine noise. The device comprises a trim tab base having a lip and a cap attached to the trim tab base to form a cavity between the lip and the cap into which the boat's exhaust is directed. The cavity has various apertures that permit the exhaust to exit the cavity and, in some embodiments, permit water to enter the cavity from below. The device may comprise baffles, outlets, inlets, and directional collars to change the flow of the exhaust. The trim tab is attached to the boat with an actuator that lets the trim tab to be adjusted at an angle relative to the boat.
US09802674B2 Power unit attachable to a bicycle
A power unit includes a drive unit and a power sprocket for engaging the transmission band of a bicycle. The power unit includes a first free-wheeling sprocket arranged on a first side of the power sprocket and a second free-wheeling sprocket arranged on a second side of the power sprocket. The power sprocket receives the transmission band from the first free-wheeling sprocket on the first side and passes the transmission band to the second free-wheeling sprocket.
US09802671B2 Control device for a bicycle derailleur
The integrated control device for driving the control cable of the derailleur and the brake cable of a bicycle is provided. The device having a support body connectable to the handlebar and that can be gripped by the cyclist's hand, a cable-winding bush about which the control cable of the derailleur is wound/unwound and a first lever rotatable with respect to the support body about a first axis for actuating the brake cable and rotatable about a second axis to drive the cable-winding bush into rotation in a first direction of rotation. An indexing mechanism connected to the first lever cooperates with the cable-winding bush to define predetermined angular positions therefor. The support body having a recess for the passage of the control cable of the derailleur.
US09802669B2 Electronic shifting systems and methods
A wireless control system for a bicycle, comprising a first shift control unit for a component of a bicycle, the first control unit comprising a radio configured to receive control signals, wirelessly transmitted by a second control unit of the bicycle; the radio operable to receive the control signals only when the radio is operating in a listen mode; and a processor configured to: activate the listen mode of the radio for a first length of time; detect, with the radio, a noise level during the first length of time; and extend the activation of the listen mode for a first extended time period when the noise level achieves a noise level threshold.
US09802666B2 Multifunctional hand guard
A multifunctional hand guard for a vehicle with a handlebar, said guard having at least three functional modes. The multifunctional hand guard includes: (a) a main hand guard body structure; (b) a cut out cover (insert); and (c) an adjustable guard shield, as well as attachment mechanisms. The cover may be inserted or removed and the shield may be up, down or in between or it may be removed, depending on weather conditions and the desire of the user.
US09802665B2 Cruise saddle
A split-nose touring bicycle seat for touring, comprising: a rigid plastic base provided with attachment points for mounting the seat to a bicycle frame; a total length of the seat of about 230-265 mm; a total width of about 270-310 mm; a split nose section formed by two elongated protrusions of substantially constant width extending forward from a medial section to a front surface; said elongated protrusions angle inwardly, a cushioned pubis bone support surface with a substantially flat side profile, and a drooped nose section forward thereof and substantially vertical outer sides.
US09802664B2 High density welding
Methods for welding motor vehicle body component subassemblies at a weld stations are disclosed. First and second pallets may be arranged for reciprocal movement between a load/unload station and the weld station and the pallets are alternately moved from a load/unload station to the weld station while the other pallet is moved from the weld station to a load/unload station. Each pallet may have a plurality of substations for receipt of component subassemblies and, while each pallet is at the load/unload station, the component subassembly at each substation is moved to the next successive substation and a further component is added to the moved component.
US09802663B1 Tab-and-slot frame members with a stringer
A frame may comprise a plurality of interlocking tab-and-slot frame members forming a three-dimensional structure. A removable stringer may be designed into one or more of the interlocking tab-and-slot frame members. The stringers may be removed after positioning and welding of tab-and slot frame members together. Notches may also be designed into and formed as additional features of a tab-and-slot frame member. Notches may serve as a guide for bending tab-and-slot frame members and in the creation of tabs and/or slots of the tab-and-slot frame members.
US09802662B2 Base rail with bumper guard for a trailer
A base rail of a trailer includes an upper portion configured to be coupled to the inner surface of a sidewall of a trailer. The upper portion includes a plurality of spaced-apart ridges configured to extend inwardly away from an inner surface of the upper portion and into a storage area of the trailer. The base rail also includes a lower portion configured to be coupled to the floor assembly of the trailer, and a bumper guard coupled to the inner surface of the upper portion and positioned between spaced-apart ridges.
US09802659B2 Spare tire carrier fuel tank
A spare tire carrier fuel tank is configured to be located between the spare tire carrier and the spare tire on a vehicle that has its spare tire mounted at a location on the upper, rear, exterior of the vehicle body. The spare tire carrier fuel tank may include a tank body having a main reservoir and a wheel reservoir. At least one structural reinforcement recess may be formed in the tank body. Multiple indentations may also be formed in the tank body in order to accommodate a variety of spare tire carriers. A mounting system may include a first mounting plate coupled to a face of the tank body and also coupled to a spare tire carrier. A second mounting plate is coupled to the first mounting plate and to a spare tire so that the tank is located between the spare tire carrier and the spare tire.
US09802658B2 Vehicle with an air guiding element for controlling aerodynamic properties and method for controlling aerodynamic properties of a vehicle
A vehicle has an underbody that rises in a rear region of the vehicle to form a diffuser and an air guiding element for controlling aerodynamic properties of the vehicle. The air guiding element is arranged on the underbody in the rear region of the vehicle. The air guiding element is reversibly transferable between a primary position and a secondary position. In the secondary position, the air guiding element and the underbody arranged behind the air guiding element, as seen in the direction of travel, are arranged forming an angle of more than 75°, preferably of more than 85° and particularly preferably of more than 90° to each other.
US09802657B2 Powered deployable spoiler assembly for motor vehicles
A powered deployable spoiler assembly includes a support member adapted for mounting to a motor vehicle and a spoiler panel disposed in a recessed segment of the support member. A pair of power-operated drive units interconnect the spoiler panel to the support member and are operable to move the spoiler panel between a non-deployed position, a first deployed position to provide aerodynamic assistance at a first vehicle speed, and a second deployed position to provide augmented aerodynamic assistance at a second higher vehicle speed. Each drive unit defines a guide slot and includes a stanchion fixed to the spoiler panel and a follower assembly fixed to the stanchion and disposed for movement within the guide slot. Electric motors are coupled to rotary-to-linear conversion mechanisms for converting rotation into translation of the follower assemblies to control movement of the spoiler panel.
US09802648B2 Vehicle lower portion structure
A vehicle lower portion structure has: a tunnel portion disposed at a vehicle transverse direction central portion of a floor portion; a front side member whose rear portion is disposed at a vehicle lower side of the floor portion and a vehicle transverse direction outer side of the tunnel portion; a first member including a first horizontal wall that extends from the rear portion toward a vehicle transverse direction inner side, and a first vertical wall bent toward a vehicle upper side from the first horizontal wall; and a second member spanning an opening portion of the tunnel portion. The second member includes a second horizontal wall, and a second vertical wall that is bent toward the vehicle upper side from the second horizontal wall, is disposed parallel to the first vertical wall, and is joined to the first vertical wall.
US09802645B2 Steering reaction force control apparatus for vehicle
Provided is a steering reaction force control apparatus for a vehicle including a driving support device configured to control an electric power steering device via a controller so that a steered angle of steered wheels reaches a target steered angle. When the driving support device is operating, the controller calculates a target steering spring torque based on a corrected steering angle corrected by a target steering angle for driving support control. When the magnitude of the corrected steering angle is less than a reference value, the target steering spring torque is calculated so that the magnitude of the target steering spring torque becomes larger in a case where the driving support device is operating compared with a case where the driving support device is not operating.
US09802643B2 Fail safe apparatus and method for MDPS system
A fail safe apparatus for an MDPS system may include: a vehicle speed sensor configured to measure a vehicle speed; a gear stage input unit configured to receive a gear stage from a transmission of the vehicle; a GPS vehicle speed calculation unit configured to calculate a GPS vehicle speed based on location information of the vehicle; and a control unit configured to determine whether the vehicle speed is an error, based on one or more of the vehicle speed, the gear stage, and the GPS vehicle speed, and determine vehicle speed data of the MDPS system based on one or more of the gear stage and the GPS vehicle speed.
US09802637B2 Steering device
Provided is a steering device including an inner pipe, an outer column including a holding main body section and a clamp section, a fixed bracket including fixed side sections, a stopper bracket including a movable guide section firmly attached to the inner pipe, and attachment sections formed at front-back-direction both ends of the movable guide section, and a hanger bracket in which sections to be attached to both the attachment sections are formed on front-back-direction both sides, the hanger bracket including side plate sections which sandwich width-direction both side surfaces of the clamp section and in which long holes for telescopic adjustment are formed. The attachment sections of the stopper bracket and the sections to be attached of the hanger bracket are firmly attached and joined by joining members.
US09802631B2 Route examining system
Systems for examining a route inject one or more electrical examination signals into a conductive route from onboard a vehicle system traveling along the route, detect one or more electrical characteristics of the route based on the one or more electrical examination signals, and detect a break in conductivity of the route responsive to the one or more electrical characteristics decreasing by more than a designated drop threshold for a time period within a designated drop time period. Feature vectors may be determined for the electrical characteristics and compared to one or more patterns in order to distinguish between breaks in the conductivity of the route and other causes for changes in the electrical characteristics.
US09802630B2 Vehicle safety railroad crossing system
A vehicle safety railroad crossing system comprising a system for preventing collisions between trains and motor vehicles at railroad crossings. The vehicle safety railroad crossing system functions to alert the train's engineer and brakeman of the vehicle ahead obstructing the tracks, and automatically apply the train's brakes to prevent a collision.
US09802625B2 Method and system for drive for setback platform system
Systems and methods for a shuttle platform that is configured to allow a path for one or more passengers to load or unload from a light rail transit vehicle that runs on a shared track. The shuttle platform can move in a linear plane and may be operationally engaged with a drive system comprising, a drive component and a combination position lock and drive mechanism disconnect. The drive component may comprise a transfer component. The combination position lock and drive mechanism disconnect may comprise: a drive disengage latch; a secondary lock latch selectably alternatively engagable between strikers; a manual drive receiver simultaneously operationally engagable with both the drive disengage latch and the secondary lock latch, and comprising a manual drive work output operationally engagable with the manual drive work input; and an automatic release.
US09802618B2 Systems and methods for improving manual transmission shifting
Systems and methods for improving shifting of a manual transmission coupled to an engine are presented. In one example, a load provided to the engine is increased in response to a transmission gear upshift so that engine speed may be quickly decreased to synchronize with transmission input speed, thereby allowing quicker manual transmission gear shifts.
US09802613B2 Driver assistance system for motor vehicles
A driver assistance system for motor vehicles, having a velocity regulation function for regulating the velocity of the subject vehicle to a nominal velocity, and having an adjacent-lane monitoring function, characterized by a turning assistance function which, when the velocity regulation function is active and an incoming signal indicates an imminent turning process that requires crossing an adjacent lane, monitors the traffic in the adjacent lane with the aid of the adjacent-lane monitoring function, and, as a function of locations and velocities of traffic participants in the adjacent lane, determines a spatial and temporal window for moving into the adjacent lane and adapts the nominal velocity to this window.
US09802608B2 Driving assist device
Provided is a driving assist device 10 that recognizes an object in the vicinity of a moving body, and assists a driver in driving the moving body, the apparatus including: an object detecting unit 12 that detects the object in the vicinity of the moving body; a three dimensional object detecting unit 13 that detects a three dimensional object in the vicinity of the moving body; and an object recognition unit 18 that recognizes the object at a predetermined detection position as a non-obstacle when the object information storing unit 16 stores the position of the object, and the three dimensional object information storing unit 17 does not store the position of the three dimensional object at the predetermined position in which detection is performed by both of the object detecting unit 12 and the three dimensional object detecting unit 13.
US09802605B2 Electric vehicle and on-board battery charging apparatus therefor
An electric vehicle and a range extender engine are shown including the controls to operate the same.
US09802604B2 Methods and systems for improving hybrid vehicle efficiency
A method for operating a driveline of a vehicle includes adjusting operation of an electric machine to provide a torque difference between a driver demand torque and an engine output torque, when the electric machine is not operating in an operating range in which electric machine efficiency is less than a threshold efficiency. The operating range has a first, positive torque limit defining a positive extent of the operating range and a second, negative torque limit defining a negative extent of the operating range. In response to the torque difference being within the operating range and greater than zero, the torque output of the electric machine is maintained at the first torque limit, whereas in response to the torque difference being within the operating range and less than zero, the torque output of the electric machine is maintained at the second torque limit.
US09802603B2 Hybrid vehicle control device and control method
A control apparatus of a hybrid vehicle that uses a combination of an engine and a traveling motor as vehicle drive sources has an engine speed detector configured to detect an engine rotational speed, an EV-state determination unit configured to determine whether a mode is an EV state in which the traveling motor is mainly used as the drive source; an EV-state annunciator configured to notify a driver about the EV state, and a switching controller configured to control switching between notification and non-notification about the EV state. The switching controller is configured to bring the EV-state annunciator to a non-notification state when the EV-state determination unit determines that the mode is not the EV state and the engine rotational speed is greater than a predetermined first threshold value.
US09802593B2 Multi-pressure valve controller and method for a vehicle braking system
A vehicle braking system includes a brake associated with a respective wheel of the vehicle, a multi-pressure valve associated with the brake, and a controller electrically communicating with the multi-pressure valve. The multi-pressure valve receives fluid at a first pressure at a supply port and is capable of delivering the fluid at a delivery port at a plurality of pressure profiles. A control signal is transmitted to the multi-pressure valve. The multi-pressure valve delivers the pressurized fluid to the brake, via the delivery port, at one of the plurality of delivery pressure profiles based on the control signal.
US09802591B2 Method and system for an aspirator for a brake booster
Methods and systems are provided for providing vacuum to a brake booster via an aspirator system. In one example, a system may include an aspirator system fluidly coupled with a brake booster with no intervening components located therebetween.
US09802590B2 Brake system for motor vehicles
The invention relates to a brake system for motor vehicle. A piston-cylinder arrangement can be actuated by means of a brake pedal, a controllable pressure source and brake pressure modulation valves. In order to provide a piston-cylinder arrangement which is easy to implement and axially short, the invention proposes that the piston of the piston-cylinder arrangement is directly guided in a housing that accommodates further components of the brake system according to the invention.
US09802588B2 Vehicle control apparatus and vehicle control method
A vehicle control apparatus which performs a travel control of a vehicle during a traffic jam, includes a wheel setting unit configured to set at least one wheel to be a brake wheel to be applied with a braking force during the travel control and at least one wheel to be a non-brake wheel not to be applied with the braking force during the travel control, and a control unit configured to perform the travel control of the vehicle based on a rotation amount of the at least one brake wheel and a rotation amount of the at least one non-brake wheel detected by a wheel speed sensor detecting the rotation amount of a wheel of the vehicle.
US09802585B2 Linkage assembly
A linkage assembly couples a plunger of a brake valve to a manually operated brake input member. The linkage assembly includes a pushrod and a resilient member. The pushrod has an end member which is engagable with the plunger. The resilient member is attached to the pushrod end member. The resilient member has an end which is engagable with the plunger when the pushrod end member is spaced apart from the plunger. The resilient member deforms to allow the pushrod end member to directly engage the plunger when the pushrod end member is moved towards the plunger. One of the end and resilient members surrounds a portion of the other of the end and resilient members. The resilient member may be a sleeve which surrounds an end portion of the pushrod. Or, the resilient member may be surrounded by a hollow end portion of the pushrod.
US09802584B2 Landing gear for power generation unit trailer system and method of anchoring trailer system
Various embodiments of the disclosure include a power generation unit trailer system. A first aspect of the disclosure provides for a landing gear for a power generation unit trailer system. The landing includes: a support configured for attaching to a base of the power generation unit trailer; and a vibration isolator attached to the support and configured to anchor the support to a foundation beneath the base.
US09802578B2 Concrete mixer truck cleaning system
A cleaning system is disclosed for cleaning concrete residue from a concrete mixer truck. The cleaning system may include a water delivery system having one or more conduits configured to deliver pressurized water to one or more spray headers positioned at various back-end portions of the truck. The cleaning system further includes one or more valves configured to control the flow of pressurized water through the one or more conduits to the one or more spray headers. In various embodiments, the one or more valves are manually operable to control the release of water to the spray headers. In other embodiments, the one or more valves are controlled by a computing device through an electrical coupling such as a communication bus. The cleaning system may be configured to clean different portions of the truck using different sets of spray headers at different times as part of a washing protocol.
US09802577B2 Wiper blade for cleaning panes in particular of motor vehicles
The invention relates to a production method and to a wiper blade for wiping panes, in particular motor vehicle panes, comprising a retaining element (12) for receiving a wiper strip (14), said retaining element having two spring rails (28, 30) which are separated from each other by a gap (32) and to which a connecting device (20) is fixed. The connecting device has a wiper blade-side part (15) with claw-like receiving portions (34, 36) that engage around the retaining element (12) at least in some regions. Each of the receiving portions (34, 36) has an internal width (42) that expands in the direction of the gap (32).
US09802576B2 End fitting having a coupling device for a wiper blade
The invention relates to an end piece (11) of a windshield wiper comprising at least one wiper blade (1). Said end piece (11) has a first part (12) and a second part (13) which are connected to each other by a removable attachment means, and a blocking means (28) for preventing the wiper blade (1) from moving relative to the end piece (11), said blocking means (28) comprising a securing device (33) and an actuating element (51). The securing device (33) is designed to pinch the wiper blade (1) and is subject to a force exerted by the actuating element (51). The end piece is for use in motor vehicles.
US09802572B2 Driver circuit for an inductor coil, method for operating an inductor coil and active transmission system with a driver circuit
In some embodiments of the present disclosure, a method for operating an inductor coil may include: charging a capacitor by means of a charging current at a reference voltage; and discharging the charged capacitor in an oscillating manner via the inductor coil. The discharging is ended when a current passing through the inductor coil has passed through an entire oscillation period or a multiple thereof.
US09802565B2 Safety system and method for operating a safety system of a vehicle
The present disclosure relates to a method for operating a safety system of a vehicle, which safety system comprises a remote sensor, an impact sensor and a protection system adapted to be activated by the impact sensor. The method includes scanning a selectable region in front of the vehicle by means of the remote sensor, determining that the selectable region provides a free path for the vehicle based on information from the remote sensor, and lowering a sensitivity of the impact sensor. The disclosure further relates to the safety system and a vehicle comprising the safety system.
US09802564B2 Method and system for alleviating the consequences of a collision
A method for alleviating the consequences of a collision of a vehicle, having a front axle and/or a rear axle with at least one roll stabilization device with which torques can be applied in the region of the front axle and/or the rear axle for the purpose of roll stabilization. In order to alleviate the consequences of collisions of vehicles, in the event of a collision protective torques are generated using the roll stabilization devices.
US09802563B2 Vehicle front portion structure provided with a pedestrian collision detection sensor
A vehicle front portion structure including: a bumper reinforcement disposed at a vehicle front end portion side such that a longitudinal direction of the bumper reinforcement is aligned with a vehicle transverse direction; a pedestrian collision detection sensor comprising a pressure tube and outputting signals based on pressure changes in the pressure tribe, the pressure tube including: a main tube disposed at a vehicle front side of the bumper reinforcement d extending along the bumper reinforcement from one end portion in the longitudinal direction of the bumper reinforcement to another end portion in the longitudinal direction thereof; and a pair of outer side tubes provided continuously with the main tube and, as viewed from a vehicle front-rear direction, extending respectively towards a. vehicle lower side from positions of the one end portion and the other end portion of the main tube; and an absorber, is provided.
US09802556B2 Electric vehicle
An electric vehicle includes a wire harness that flexibly follows the swinging of the swing arm, surely avoids any contact with other components, and has excellent durability. The electric vehicle includes a battery mounted to a frame, an inverter and an electric motor accommodated in a swing arm, and a wire harness wired between the frame and the swing arm. The swing arm includes a hollow pivot section, and a partition wall partitioning the pivot section and an arm section. The wire harness suspends from the frame side, enters inside the pivot section from the top face side of the pivot section, and is bent inside the pivot section reaching the inverter through the partition-wall through port.
US09802555B2 Vehicle body seal with trim strip
An arrangement having a sealing profile of a vehicle body seal and a trim strip connectable to the sealing profile with the trim strip being pressed against the sealing profile perpendicularly to the longitudinal direction of the profile. Two connecting projections running parallel to and at a distance from each other in the longitudinal direction of the strip protrude from the trim strip. The sealing profile has groove recesses running in the longitudinal direction of the profile for receiving one connecting projection each. The connecting projections are undercut, as seen counter to the press-on direction, and the groove recesses are undercut in the press-on direction. The undercuts of the groove recesses are formed by rib projections for engagement in one undercut each of the connecting projections. The rib projections are tongues which are elastically bendable by the connecting projections when the trim strip is pressed onto the sealing profile.
US09802551B2 Method for manufacturing a vehicle interior trim part as well as a vehicle interior trim part
The present subject matter relates to a method for manufacturing a vehicle interior trim part comprising a decor layer which forms a groove, as well as a decor element which is welded in the groove) of the decor layer, wherein the decor element is brought into the groove and is subsequently fixed in the groove by way of welding. According to the present subject matter, a welding head, e.g. an ultrasound sonotrode, is used for welding, and this comprises a contact side which is equipped with a plurality of projections which are arranged distanced to one another in a row and which taper to their contact surfaces, and wherein the welding head for producing the seam is pressed against a rear side of the decor layer in the region of the groove, in a manner such that the individual projections of the row of projections in a longitudinal directions of the groove come into contact with the rear side of the decor layer in a manner offset to one another, wherein the projections have a width which corresponds at least to 50% of a width of the decor element.
US09802545B1 Motor vehicle ice sensor assembly and method of operation
A frozen accumulation detection assembly and method of operation for a motor vehicle is provided. The assembly includes a light source for emitting light on a surface of the motor vehicle, such as running board, and a sensor for measuring a reflectance level of the light off of the surface of the motor vehicle. The assembly further includes a heating element coupled to the surface of the motor vehicle. The reflectance level may be used as an indicator of frozen accumulation on the surface of the motor vehicle, and may help determine if the heating element should be energized.
US09802536B2 Acoustic feedback system
An acoustic feedback system includes a memory and processor to receive at least one of a plurality of output signals from a plurality of sensors. The system determines whether an output signal has reached a first threshold, and sends an audible sound signal to a speaker(s) based on the first threshold. Thus, the acoustic feedback system utilizes output signals of various vehicle sensors and generates audible signals based on the sensor output signals.
US09802534B1 Illuminated vehicle compartment
A vehicle is provided herein that includes a pickup box defining a storage compartment therein. A liner is disposed on an exterior surface of the pickup box. A first luminescent structure is disposed within the liner and is configured to luminesce in response to receiving excitation light from a first light source.
US09802532B2 System for detecting surrounding conditions of moving body
This system for detecting the surrounding: conditions of a moving body forcibly changes the state of at least one of a plurality of lighting devices (change from an unlit stats to a lighting state or a blinking state, change in the emission color, or change in the luminance) installed inside the moving body if an object to which attention must be paid during traveling of the moving body is detected in the surroundings of the moving body.
US09802529B2 Method for controlling a cornering light and lighting device
The invention relates to a method for controlling a predictive cornering light with at least one headlight with a pivoting means for the controlled pivoting of the headlight, wherein a monitoring device is provided, which monitors the roadway and/or lane in front of the vehicle, and a control unit is provided, which, on the basis of the data of the monitoring device, drives the pivoting means for setting the headlight for illuminating the roadway and/or lane. The invention also relates to a lighting device in this regard.
US09802528B2 Driver assist device and industrial truck with driver assist device
A driver assist device is described for an industrial truck (1) with at least one steered wheel (21) at the rear end of the truck. The driver assist device is located on the industrial truck (1) and projects a lighting effect on the roadway (13). The lighting effect marks a peripheral path (12) of the external periphery (14) of the rear end (15) of the truck on the roadway (13) for a selected steering angle as the industrial truck travels in a curve.
US09802522B2 Vehicle beverage holder
A holder for a vehicle that temporarily holds and continuously adjusts the orientation of a beverage container filled with a liquid that prevents spills as the vehicle is moving. The holder includes a base with an upper hole with a smooth perimeter edge and a suspended beverage container vessel that fits into the upper hole and rests against the perimeter edge. The container vessel includes a downward extending, half-spherical upper member and a lower neck. Formed inside the container vessel is a center bore that receives a complimentary shaped beverage container. The upper member and the perimeter edge on the base are configured to form a gripping space between the beverage container and the upper member. When the lower neck is placed inside the upper hole, the base's perimeter edge supports the upper member and allows the vessel to swivel freely when a beverage container is placed in the vessel.
US09802521B2 Multilayer seat
A vehicle seat includes a lower seating structure and a raised seatback support, wherein one of either the lower seating structure or raised seatback support consists of a multilayer assembly. The multilayer assembly includes a flexible static layer, a flexible dynamic layer having an adjustable firmness, a suspension layer formed from tunable springs which support a flexible panel, and a frame supported carrier including a protective recess within which the suspension layer is cradled.
US09802520B2 Vehicle seat having a horizontally movable seating surface for receiving a person
The invention relates to a vehicle seat with a horizontally movable seating surface for receiving a person, a retaining means which can be rigidly connected to a vehicle, and a horizontal spring system and a vertical spring system, wherein both the horizontal and vertical spring systems are configured as fluid systems, wherein the fluid systems are supplied by a central fluid supply and the fluid system of the horizontal spring system being separated from the fluid system of the vertical spring system by at least one valve.
US09802518B2 Pneumatic adjustment arrangement for a vehicle seat
A pneumatic adjustment arrangement for a vehicle seat. The pneumatic adjustment arrangement has at least one chamber or bladder, which can be filled with a pressure medium, as an adjustment element. Furthermore, the pneumatic adjustment arrangement has a fluid line for the filling and/or evacuation of the chamber. Additionally, the pneumatic adjustment arrangement has a valve device which is provided in the fluid line for volume flow regulation. Finally, the pneumatic adjustment arrangement has a noise absorber which is likewise arranged in the fluid line in order to absorb noise generated in the fluid line. In this way, it is possible to create a pneumatic adjustment arrangement for a vehicle seat, in particular for comfort functions, such that objectionable noises during the execution of the comfort fiction are reduced.
US09802514B2 Seat for a law enforcement vehicle and method of use
Disclosed is a method of use of a movable seat for a law enforcement vehicle. A method of restraining a detainee within a vehicle may include the steps of: opening a door on a vehicle comprising a movable seat; retracting the movable seat from a first position in the vehicle to a second position adjacent the door of the vehicle; seating a detainee in the movable seat of the vehicle; wherein the detainee's hands are restrained behind its back; positioning the detainee's hands in an opening in a back of the movable seat; restraining the detainee in the movable seat with a seat belt coupled to the movable seat; returning the movable seat to the first position inside the vehicle; and closing the door on the vehicle.
US09802505B2 Fuel cell vehicle and control method therefor
With a fuel cell vehicle includes a fuel cell and a secondary battery, a drive motor and a pump motor are connected to each other via an electric power line so that the drive motor and the pump motor are capable of receiving and supplying electric power with each other without involving reception and supply of electric power with the secondary battery. The control device determines an upper-limit guard value of torque of the pump motor based on a dischargeable power of the secondary battery and an output power of the fuel cell, or determines a lower-limit guard value of torque of the pump motor based on a chargeable power of the secondary battery and an output power of the fuel cell.
US09802502B2 Method and system for creating a reserve energy banking and energy reserve network
A method for creating a collective energy reserve network is provided. The method includes receiving first data including location data and first energy reserve interest data from a first remote device; receiving second data including location data and second energy reserve interest data from a second remote device; and using the first location data, first energy reserve interest data, second location data and second energy reserve interest data to permit creation of a first collective energy reserve. The energy reserve may be free standing or integrated with an electric vehicle recharger.
US09802500B1 Methods and systems for electric vehicle (EV) charging and cloud remote access and user notifications
Systems and methods for charging an electric battery of a vehicle are provided. The vehicle includes a battery for powering an electric motor of the vehicle. A controller of the vehicle is provided to interface with a battery and to enable control of charging of the battery. The vehicle includes a communications interface for enabling wireless communication with a server, and the server is configured to manage a plurality of user accounts for users. The server is one of a plurality of servers, and the servers providing access to cloud services regarding vehicle use and metrics.
US09802496B2 Charging vehicle, charging system and driving method of charging system
A charging system includes: first stations configured to determine whether to transmit charger detection signals based on a preset charging mode and a state of charge of a battery included in a vehicle; and second stations configured to receive the charger detection signals or to transmit beacon signals to the transmitter based on the state of charge of the battery.
US09802495B2 Off-board charger for high-voltage battery charging
An off-board battery charger for a vehicle may include a high-voltage connector having first, second and power supply connector ports. The first connector port connects to a vehicle controller via a first cable. The second connector port connects to a vehicle battery via a second cable. And, the power supply connector port is electrically connected with the second port and receives power via a power supply cable from a separate and external power supply.
US09802487B2 Speedometer drive system and method
A speedometer system is disclosed that replaces reliance on the feedback from a vehicle transmission and instead tracks the vehicle speed from an external source. In some embodiments, a global positioning unit (GPS) is connected to a microcontroller that drives an electric motor to turn and display a speed for an improved speedometer reading. The speedometer system further including a calibration unit that allows for the manipulation of the electric motor to display a predetermined calibration speed on the speedometer.
US09802486B2 Interior display systems and methods
System and method for using an interior display device in a vehicle. The interior display device includes a projection device and a controller. The controller is configured to receive a plurality of vehicle parameters and determine an expected location within an interior of the vehicle based on the plurality of vehicle parameters. The expected location corresponds to an interior area of the vehicle where a driver would be expected to look. The controller is further configured to select an image (515, 520) based on the plurality of vehicles parameters and operate the projection device to project the image at the expected location within the interior of the vehicle.
US09802484B2 Method and display device for transitioning display information
A method for displaying information, in which at least one first graphical object is graphically displayed on a display area, and, in the case of a change to a second graphical object, a control device generates graphic data that control the display area in a manner that causes the first object to disappear and the second object to be faded in. In the case of a change to the second object, the control device generates graphic data that control the display area such that, in the perspective representation on the display area, the first graphical object is swiveled out about a first axis disposed outside of the display area; and, in the perspective representation on the display area, the second graphical object is swiveled in about a second axis disposed outside of the display area, until it is fully displayed.
US09802480B2 High-pressure tank
Provided is a high-pressure tank that includes a tank main body including a mouthpiece, a valve fitted to the mouthpiece, and a pipe extending from the valve in an axially inward direction of the tank main body and for ejecting a gas into the tank main body. The pipe includes an ejection nozzle provided at an end of the pipe and for ejecting the gas, a first bent portion located between the ejection nozzle and the valve and extending in a direction inclined relative to an axial direction of the tank main body, and a second bent portion having the ejection nozzle and extending in a direction inclined relative to the axial direction. One of an inclination angle of the first bent portion relative to the axial direction and an inclination angle of the second bent portion relative to the axial direction is larger than 0° and not larger than 90°, and the other is not smaller than −0° and smaller than 0°, when the pipe is viewed in a direction perpendicular to the axial direction.
US09802478B2 Fuel tank depressurization before refueling a plug-in hybrid vehicle
A method for operating a vehicle system is provided. The method includes monitoring a change in a temperature of the fuel vapor canister coupled to a fuel tank via a canister temperature sensor and adjusting operation of a fuel tank isolation valve based on the change in temperature of the fuel vapor canister.
US09802476B1 Method and system for forming a self-sealing volume using a breather system
A fabric and elastomeric material (referred to as a fabric trilayer) combined with a sealant may be applied in such a fashion so as to eliminate or minimize air entrapment in an elastomeric composite structure that forms a seal-sealing volume. The performance of the self-sealing volume is dramatically improved with this minimizing of air entrapment. Surprisingly and unexpectedly, this construction approach may be accomplished without significantly adding to the weight or thickness of the volume and without affecting the outer dimension of the self-sealing volume. Thus, a method and system for forming a self-sealing volume are described. The system includes an elastomeric composite structure comprising at least one layer of an elastomeric material derived from a neat (no solvent) elastomeric material that does not substantially react at room temperature.
US09802475B2 Motor vehicle front end part
A motor vehicle front end part (1) has a device for influencing a cooling air flow. The device has an adjustable flap (22) that extends in a vehicle transverse direction and that is assigned to an air inlet opening (10) with an air inlet cross section (12). To provide a motor vehicle front end part that is of simple design and can be produced cost-effectively, the flap (20) is arranged in front of the air inlet cross section (12) in a vehicle longitudinal direction to such an extent that, if the flap (20) is in an operative position, the cooling air flow (22, 23) is channeled completely or virtually completely past the air inlet opening (10).
US09802473B2 Grill assembly
A grill assembly is disclosed. The grill assembly includes an air inlet screen. The air inlet screen is configured to allow passage of air therethrough. The grill assembly also includes a base frame. The base frame is attached to the air inlet screen. The grill assembly further includes a plurality of trusses. The plurality of trusses is connected to the base frame. The grill assembly includes a motor affixed to the trusses. The motor is configured to mechanically vibrate the trusses. Further, the trusses are arranged in a manner such that the air inlet screen is configured to vibrate during an operation of the motor.
US09802465B1 Visor assembly for a vehicle
A visor assembly for a vehicle includes a visor housing including a first side and a second side spaced apart from and cooperating with the first side to define an outer periphery having an opening extending through the first and second sides of the visor housing and an inner periphery having at least one receiving surface cooperating with the opening. At least one support is disposed in the inner periphery of the visor housing and cooperating with the at least one receiving surface. A cover panel having an elongate body received is within the channel and movable relative to the at least support between at least a first position at least partially covering the opening and a second position. A biasing member selectively positions the cover panel in the second position.
US09802463B2 Vehicular air-conditioning unit
A vehicular air-conditioning unit has an air-conditioning case, a first ventilation passage and a second ventilation passage, a first communication-ventilation passage defined in the air-conditioning case, the first communication-ventilation passage through which one end of the first ventilation passage communicates with one end of the second ventilation passage, a first heat exchanger that heats or cools air flowing in the first ventilation passage, a second heat exchanger that heats or cools air flowing in the second ventilation passage, and a blowing mode switching device setting any one of blowing modes. The blowing modes include (i) a first blowing mode in which air is blown into a vehicle compartment after flowing through the first ventilation passage and in which air is blown into the vehicle compartment after flowing through the second ventilation passage and (ii) a second blowing mode in which air flows into the second ventilation passage through the first communication-ventilation passage after flowing through the first ventilation passage and is blown into the vehicle compartment.
US09802461B2 Cooling system for vehicle
A cooling system for a vehicle comprises an engine cooling means that circulates a coolant to an engine and cools the coolant in an engine radiator, the engine being provided with a turbocharger; an electrical equipment cooling means that circulates the coolant to an electrical equipment comprising a motor and an electric power component, and cools the coolant in an integral radiator; and an air conditioner comprising a water-cooled condenser that primarily condenses a refrigerant and an air-cooled condenser coupled in series to the water-cooled condenser that secondarily condenses the refrigerant and that cools or heats a vehicle interior through the refrigerant, wherein the water-cooled condenser is disposed within the integral radiator and an intercooler mounted at an intake side of the engine uses the coolant to cool water and is connected to the electrical equipment cooling means.
US09802460B2 Electric vehicle thermal management system with series and parallel structure
Electric vehicle thermal management systems and electric vehicles using the thermal management system, are disclosed. A passenger cabin is heated by the heat dissipated from a battery and/or a motor. A cooling circuit in the management system fluidly connects the battery, the motor and a first radiator in series. The first radiator provides a heat source to the passenger cabin by means of the heat dissipated from the battery and/or the electric motor. Under certain conditions, the electric motor is selectively separated from the cooling circuit, so that when the passenger cabin needs to be heated, the thermal management system can provide heat to the passenger cabin without affecting the heat dissipation of the battery.
US09802458B2 Motor vehicle with a water box and an air conditioner
A car having a water box comprising an outer face, an inner face, an air inlet opening, an air outlet opening and a water outlet opening. The inner face forms a water separating space that is connected to the air inlet and outlet openings and the water outlet opening. The water outlet opening discharges water out of the separating space. An air conditioner is connected to the air outlet opening to feed air from the water box into the air conditioner. An air feeding unit sucks the air into the air conditioner via the air inlet opening. The air feeding unit is designed as a suction fan. The water box comprises a wall that comprises fibers forming a non-woven fabric i.e. felt.
US09802457B2 Vibration damping device for a vehicle body
A damping force change mechanism includes an on-off valve located in a through hole of a piston rod. The on-off valve opens/closes a third hydraulic oil passage that allows a first oil chamber on a free piston side and a second oil chamber between a first piston and a second piston to communicate with each other. The on-off valve includes an expanded diameter portion in the first oil chamber extending outward in the radial direction. The expanded diameter portion faces the entire opening edge of the through hole and tightly contacts an end surface of the piston rod. The magnitude of a damping force is easily changed, and a damping force characteristic in a case in which the damping force is large is stabilized.
US09802452B1 Gooseneck hitch with dampening assembly and kingpin adaptor
A hitch with a force dampening assembly and a kingpin adapter. The hitch includes upper and lower arms coupled via a dampening assembly that includes a resilient member disposed in a passage in the lower arm and an axle coupled to the upper arm and disposed coaxially through the resilient member. Facets or asymmetries on the passage and axle resist rotational movement of the resilient member relative thereto. The resilient member is flexed between the wall of the passage and the axle to enable pivotal movement of the upper arm relative to the lower arm. The kingpin adapter includes a wedge ring disposed on a kingpin and retained thereon by a clamping ring. A housing is coupled to the clamping ring to affix the housing to a trailer and to retain the wedge ring in position. A hitch can be coupled to the housing.
US09802447B2 Tire pressure monitoring system
A tire pressure monitoring system includes a tire valve stem mounted tire pressure gauge and an externally powerable remote display unit. The pressure gauge includes a pressure sensor, a wake circuit, a processor, and a first radio frequency (RF) module. The remote display unit includes a second RF module and a display. The wake circuit is adapted to activate the processor periodically at a predetermined interval of time and causes the processor to receive an output signal from the pressure sensor. The output of the pressure sensor is indicative of a tire pressure detected by the pressure sensor. The remote display unit is adapted to display the measured tire pressure value without any user input.
US09802446B2 Self-sealing tire sealant and pneumatic vehicle tire
Self-sealing tire sealants are provided which contain fragments and/or residues of expanded solids, where the solids are selected from the group containing expandable graphite and microspheres. In some aspects, the microspheres include at least isobutane and/or isopentane as blowing agents. The microspheres may also have a shell containing at least one polymer, and in some cases the polymer is at least one copolymer of acrylonitrile and methyl acrylate. The self-sealing tire sealant may further include graphene structures. In some aspects the interior of a pneumatic vehicle tire has the self-sealing tire sealant disposed on the inner surface, opposite the tire tread, and the layer thickness of the tire sealant may be from 0.5 to 8 mm.
US09802445B1 Apparatus for noise reduction of tire of vehicle
An apparatus for noise reduction of a tire reduces noise within a particular frequency range generated in the tire during operation of a vehicle. The apparatus includes a housing mounted on a wheel rim, the tire being fitted over the wheel rim, and the housing having an inner space; a resonant cover provided in the inner space of the housing; and a resonance hole formed in the resonant cover to allow the inner space of the housing and an inside of the tire to communicate with each other so that the resonant cover controls pulsation via air entering and exiting through the resonance hole.
US09802444B2 Pneumatic tire
A pneumatic tire (10) has, in the surface of the tread (11), a central circumferential groove (12) located at the center of the contact patch width and extending circumferentially around the tire, a plurality of longitudinal grooves (13 (13a, 13b)) formed on the axially outside of the central circumferential groove (12), lug grooves (15), and blocks (16 (16a to 16c)) defined by the central circumferential groove (12), the longitudinal grooves (13), and the lug grooves (15). Each of the lug grooves (15) is formed such that its width in the shoulder region is greater than its width in the central region, and the sum of the groove area of the central circumferential groove (12) and the groove area of the longitudinal grooves (13) is smaller than the area of the lug grooves (15). As a result, the pneumatic tire (10) not only secures the wet braking performance and wear resistance performance on paved roads, but also improves the acceleration performance and braking performance and the steering stability performance on snowy roads.
US09802442B2 Heavy duty tire
A heavy duty tire has a carcass extending from a tread portion to a bead core in a bead portion through a sidewall portion, and a belt layer disposed on the outside of the carcass in the tire radial direction and on the inside of the tread portion. In a state in which a distance between a pair of bead heels is kept at 110% of a wheel rim width of a standard wheel rim and no inner pressure is applied, the contour shape of the tread portion is formed by a 1st circular arc having a center on the tire equatorial plane, and a pair of 2nd circular arcs, disposed on both outsides of the 1st circular arc in the tire axial direction. The radius of the 2nd circular arc is more than the radius R1 of the 1st circular arc. One 2nd circular arc has the center on the other 2nd circular arc side of the tire equator in the tire axial direction, and the other 2nd circular arc has the center on the one 2nd circular arc side of the tire equator in the tire axial direction.
US09802441B2 Magnetic chalk line
A magnetic chalk line provides a powerfully magnetized fastener, which may be secured magnetically to any flat metal surface, such that it will remain secured when the line is drawn out of its spool and snapped. A hook end is provided which may be hooked to the edge of a surface, such as a steel plate, girder, wooden stud, or drywall sheet. A teardrop-shaped aperture is provided in the fastener, enabling the user to easily secure it to a nail head when working with wood or other non-metallic materials.
US09802428B2 Target transport apparatus and liquid ejecting apparatus
A target transport apparatus includes a transport roller pair that has a plurality of segmented roller members disposed at intervals in a width direction that intersects with a transport direction of continuous paper and that imparts a transport force on the continuous paper by the segmented roller members pinching the continuous paper; and an image capturing unit, disposed in a location that corresponds to a pinched area in the width direction of the continuous paper that is pinched by the segmented roller members and to the pinched area along the transport direction, that detects, without making contact with the continuous paper, an amount by which the continuous paper is transported by the transport roller pair.
US09802425B2 Printing device and printing method
A printing device and a printing method, which are by ink-jet technique an overcoat layer using an ink consisting of more suitable ingredients, are provided. The printing device is for performing printing by ink-jet technique, including: a color ink head being an inkjet head that forms a color ink layer on a medium using a color ink; an overcoat head being an inkjet head that forms an overcoat layer that covers the color ink layer; and a curing agent head being an inkjet head that discharges ink droplets of a curing agent, the curing agent being a liquid for curing an ink in the overcoat layer. The overcoat head discharges ink droplets of an ink prepared by dispersing in an organic solvent a curable material that is cured in reaction to the curing agent.
US09802424B2 Method and device for inkjet printing on containers
In a method and a device for inkjet printing on containers, at least a first and a second subprint complementing each other in the printing direction so as to form a print image are joined. The first subprint is printed starting from a connection area or up to a connection area. Subsequently, the second subprint is printed with a feed towards the connection area such that the first and second subprints interleavingly overlap in the connection area. This allows a joining of subprints with unobtrusive transitions even in the case of dimensional tolerances and complicated cross-sections of the respective container.
US09802419B2 Liquid cartridge
A liquid cartridge includes a first surface and a second surface facing a particular direction, with a liquid outlet through the first surface. A circuit board is mounted on the second surface, and a liquid detection mechanism including a light access portion extends above the second surface further than the circuit board in the particular direction.
US09802417B2 Liquid container and liquid ejection system
Leakage of liquid from a liquid container is reduced. A liquid container capable of containing liquid has: a liquid containing portion capable of containing the liquid; a liquid inlet port receiving injection of the liquid into the liquid containing portion; an atmosphere opening port communicating with the liquid containing portion and introducing atmosphere into the liquid containing portion; an atmosphere communicating portion leading to the liquid containing portion from the atmosphere opening port; a first face oriented outward; and a second face oriented outward in a direction that is different from a direction of the first face. The atmosphere communicating portion includes a plurality of atmosphere chambers, and the plurality of atmosphere chambers include a first atmosphere chamber provided in the first face, and a second atmosphere chamber provided in the second face.
US09802413B2 Photopolymerizable inkjet ink
To provide a photopolymerizable inkjet ink, which contains photopolymerizable monomers containing at least one selected from the following compound group (A) compounds of which are negative for skin sensitization, and at least one selected from the following compound group (B) compounds of which are negative for skin sensitization, wherein the compound group (A) is a compound group consisting of caprolactone-modified dipentaerythritol hexaacrylate, polyethoxylated tetramethylol methane tetraacrylate, ethylene oxide-modified bisphenol A diacrylate, caprolactone-modified hydroxy pivalic acid neopentyl glycol diacrylate, polypropylene glycol diacrylate [CH2═CH—CO—(OC3H6)n-OCOCH═CH2 (n≈12)], hydroxyethyl acryl amide, trimethylol propane trimethacrylate, and tricyclodecane dimethanol dimethacrylate, and the compound group (B) is a compound group consisting of ethylene oxide-modified phenolacrylate, isostearyl acrylate, ethylene oxide-modified trimethylol propane trimethacrylate, stearyl methacrylate, and glycerin dimethacrylate.
US09802411B2 Print device and non-transitory computer readable medium
A nozzle arrangement of a head portion of a printer includes nozzle arrays arranged in a first direction. Each of the nozzle arrays has nozzles arranged in a second direction crossing the first direction. Each of the nozzles is provided to eject liquid. The printer includes a set of liquid passages provided to supply the liquid to the nozzle arrangement. The set of liquid passages has liquid passages interconnected via a communication path. The nozzles in each of the nozzle arrays is connected to a corresponding one of the liquid passages. In selective flushing that is performed a plurality of times, among the nozzles configuring the nozzle arrays, liquid is ejected from the nozzles arranged in a first region adjacent to the communication path.
US09802409B2 Adjustment mechanism and adjustment method
An adjustment mechanism is structured to adjust and fix a liquid discharge head in position on a base plate. The adjustment mechanism includes a first plate, a second plate, a pivotable cam, and a first biasing unit. The first plate is changeable in position in a circumferential direction relative to the base plate. The first plate is fixed to the base plate. The second plate is mounted on the first plate movably relative to the first plate in a direction different from the circumferential direction. The liquid discharge head is fixed to the second plate. A first biasing unit biases the second plate toward the pivotable cam in a horizontal direction to prevent the second plate from lifting upward off the first plate. The pivotable cam is operable to move the second plate against an biasing force of the first biasing unit and to locate the second plate.
US09802406B2 Liquid jet head and liquid jet device
The present invention relates to a liquid jet device comprising an actuator plate on which injection channels and non-injection channels are arranged side by side, a cover plate laminated on a surface of the actuator plate and including slits communicating into the injection channels, common electrodes and individual electrodes formed on inner surfaces of the injection channels and the non-injection channels, and common wires and individual wires formed on surfaces of bank portions of the actuator plate, and common pad portions and individual pad portions connected to the common wires and the individual wires, and connected to flexible boards in protruding end portions are formed in a portion of a back surface of the cover plate outside the slits.
US09802402B2 Method of manufacturing heating device by screen printing
A method of manufacturing a heating device includes preparing a substrate having a curved surface; and forming a heating body on the substrate, the heating body generating heat with a supply of electric current. The forming of the heating body includes pressing a screen toward the substrate with an aid of a pressing member while rotating the substrate and moving the screen, and transferring application liquid that is to form the heating body to the substrate through the screen. In the forming of the heating body, the pressing member is in contact with the screen at a position on an upstream side with respect to a transfer position in a direction of movement of the screen.
US09802401B2 Frame assembly, stencil, screen printing device and screen printing method
The present invention provides a frame assembly, which comprises a first frame and a second frame provided to surround the first frame. The first frame and the second frame are configured to support mesh fabric therebetween.
US09802396B2 Synthesis of quantum dot/polymer/layered-structure ceramic composite
The present invention relates to a quantum dot and a preparation method therefor, and more specifically, to a novel quantum dot composite having high surface stability, and a preparation method therefor. The quantum dot composite according to the present invention constitutes a layered-structure ceramic composite in which the layered-structure ceramic comprises a polymer-quantum dot composite between the layers thereof.
US09802394B2 Machine direction oriented film for labels
Machine direction oriented multilayer film suitable for preparing labels, comprising a core layer of a bimodal terpolymer and two outer layers comprising HDPE.
US09802379B2 Method for manufacturing extended content booklet labels
A method of manufacturing an extended content booklet label. Sheets are parallel folded to form a spine of a multi-up book log. The book log is overlaminated with an overlaminate to a major web having a longitudinal direction so that the spine is oriented perpendicular to the longitudinal direction of the web. The major web is continuously moved passed three or more longitudinally aligned cutting elements. Each cutting element cuts deeper than the previous cutting element for progressively slitting the major label web and overlaminated multi-up book log in the longitudinal direction only to form two or more minor webs.
US09802377B2 Autoclave
An autoclave suitable for use for heating articles such as tires is described. The autoclave includes an elongated chamber having an interior section and an annular duct surrounding the interior section, wherein the annular duct is separated from the interior section by a dividing wall; said autoclave further including a heat source for heating the air, a fan for circulating the air in the chamber, and an air deflector mounted in a distal end of the chamber. The air deflector is positioned to redirect the airflow towards the interior portion of the chamber to eliminate air recirculation zones and improve the temperature uniformity.
US09802376B2 Process for building tyres and tyre obtained thereby
A pair of annular inserts of elastomeric material is circumferentially applied by spiraling around a laying surface of an auxiliary drum. Then a plurality of strip-like elements disposed in parallel side by side relationship with each other in the circumferential extension of the laying surface is applied onto the auxiliary drum, so as to form at least one first belt layer. Respectively opposite end portions of each strip-like element are radially superposed, each against one of the annular inserts, so that each of the annular inserts projects from a respective end edge of the strip-like element. The cap structure formed on the auxiliary drum is coupled to a carcass structure through toroidal conformation of the latter, in such a manner that the radially external ends of sidewall portions previously manufactured on the carcass plies are associated with the axially external ends of the annular inserts.
US09802371B2 Apparatus for molding composite materials
A method and apparatus for shaping, compacting, and supporting a composite material (C) contained between two flexible membranes (G, F) and capable of being stretched over a porous mold (A) are described. The apparatus enables the use of inexpensive mold despite the high pressures used. A counter-mold (M) having the same characteristics as the mold can be used in certain instances. The equipment enables the use of a plurality of molds and counter-molds during one manufacturing cycle.
US09802368B2 Methods and systems for manufacturing advanced composite components
A fiber placement system for manufacturing composite components includes at least one material storage enclosure including a material spool assembly, a swiveling roller assembly, and a redirect roller assembly, for each tow to be produced per course, at least one material feeding/cutting station configured with a nip roller drive system, and a cutting mechanism, at least one material transfer station configured with an individual, moveable guide tray for each tow to be produced per course, the moveable guide trays respectively being configured with a vacuum system, and at least one layup station comprising a vacuum table/layup surface, and a pick-and-place device equipped with an end-effector.
US09802365B2 Hollow wall composite tube, methods of production and uses thereof
A hollow wall composite tube for improving performance in sports shafts and lightweight structural members is disclosed that includes: a constituent tube, for forming the wall, that comprises: a flexible core component, for providing an adjustable shape on which to wind or braid filaments or fabric; and an adjustable shape hollow structure, for reducing weight, providing a path for the core to be evacuated, tightly conformed to the core, and tow, braid filaments or fabric, for providing a reinforcing fiber matrix for saturation with epoxy, spirally wrapped, applied or braided on the constituent tube. Methods of producing contemplated composite tubes are also disclosed.
US09802362B2 Three-dimensional formation apparatus, three-dimensional formation method, and computer program
A three-dimensional formation apparatus includes a head-unit which can discharge liquid in a first-direction and a control-unit which controls the head-unit. The control-unit forms a hollow on a changed portion where an outline of a cross section object is simultaneously changed in a second-direction and a third-direction towards the inside from the outline of the cross section object in the second-direction or the third-direction, in a first cross section object formation process and executes a filling process of discharging the liquid containing a second quantity which is larger than a first quantity to the hollow so as to come in contact with the cross section object formed in the first cross section object formation process, to fill at least a part of the hollow with the liquid, after the first cross section object formation process is executed and before the second cross section object formation process is executed.
US09802360B2 Platen planarizing process for additive manufacturing system
A method for printing a three-dimensional part with an additive manufacturing system, the method comprising generating and printing a planarizing part having a substantially-planar top surface relative to a build plane, and a bottom surface that substantially mirrors a topography of a platen surface, and printing the three-dimensional part over the substantially-planar top surface of the printed planarizing part.
US09802358B2 Curable prepregs with surface openings
Curable prepregs possessing enhanced ability for the removal of gases from within prepregs and between prepreg plies in a prepreg layup prior to and/or during consolidation and curing. Each curable prepreg is a resin-impregnated, woven fabric that has been subjected to a treatment to create an array of openings in at least one major surface. Furthermore, the location of the openings is specific to the weave pattern of the fabric.
US09802354B2 Sheet processing apparatus, image forming system, and pair of rotating members
A sheet processing apparatus includes a rotating member, a switching unit, and a pressing unit. The rotating member is rotatable and has a facing portion that faces a fold section of a sheet. The rotating member rotates so as to switch the facing portion to another facing portion. Each facing portion is provided with a protrusion. A set position of the protrusion in an axial direction varies from facing portion to facing portion. The switching unit rotates the rotating member so as to switch the facing portion that faces the fold section. The pressing unit presses the protrusion of the facing portion against the fold section.
US09802349B2 Wafer level transfer molding and apparatus for performing the same
A method includes placing a package structure into a mold chase, with top surfaces of device dies in the package structure contacting a release film in the mold chase. A molding compound is injected into an inner space of the mold chase through an injection port, with the injection port on a side of the mold chase. During the injection of the molding compound, a venting step is performed through a first venting port and a second venting port of the mold chase. The first venting port has a first flow rate, and the second port has a second flow rate different from the first flow rate.
US09802348B2 Heater and thermocouple assembly
A heater and thermocouple assembly for use with a hot runner nozzle with an elongated heater body, said heater body having at least one first heating section, which in operation is positioned adjacent to the front end portion of the hot runner nozzle, and at least one second heating section which in operation is positioned adjacent to a nozzle head of the hot runner nozzle and has an at least partly annular distance section with a wall which is arranged between the first and second heating sections.
US09802346B2 Variegated building product and method
A method of molding a building product may include providing an injection mold with a plurality of gates located adjacent a perimeter of the injection mold. The method may further include commingling a first material and a second material into a flow. The second material may be a color that contrasts with a color of the first material. The method may include injecting the commingled flow into the plurality of gates to form an injection molded building product, and removing the molded building product from the injection mold. In addition, the second material may extend through an interior of the molded building product and appear as contrasting streaks on an exterior of the building product to form a variegated grain appearance.
US09802333B1 Sign making apparatus and method
A kit for making a sign utilizing a router includes a plurality of interlocking templates that can be utilized to form the letters for a sign. The kit includes two or more templates that are positioned in the same location on a board in a sequence to form a single letter, number or symbol with an island with an uninterrupted perimeter. The kit also includes a guide bushing that is secured to the router bit to prevent the router bit from gouging into the templates.
US09802330B2 Document production system and method with automated die exchange
A media cutting system is disclosed comprising a die cutter including a cutting surface and a plurality of dies stored proximate the cutting surface, a die exchange system including a die storage system configured to support the plurality of dies and a die transport system, and a computer system comprising a controller configured to operate the die transport system and the die cutter. A die exchange system and methods of making and using the die exchange system also are disclosed.
US09802329B2 Device for cutting extruded plastic profiles to length
A device for cutting a preferably thick-walled, extended pipe to length, has at least one cutting tool and a receiving unit for the cutting tool. The cutting tool is radially movable in relation to the extrusion axis and is rotatable via further means about the pipe to be cut to length, in order to cut the pipe to length. The receiving unit may be connected by means of a receiving disc to a sleeve via a ring element, wherein linear guiding elements are arranged on said sleeve parallel to the extrusion axis, and wherein at least four linear guiding elements are evenly distributed around the circumference of the sleeve.
US09802325B2 Robotic end effector tool with one piece fixed frame system
The present invention is directed to tool arrangement having a one piece frame. The one piece frame that is solid and non-adjustable and includes a back side, front side and one or more extension walls extending away from the front side of the one piece frame. An attachment portion is located on said back side of the one piece frame for connecting the tool arrangement to a robotic arm. The one piece frame has at least three mounting locations formed at predetermine locations on said one piece frame. The at least three mounting locations are predetermined and non-adjustable locations on the one piece frame. The tool arrangement includes a stationary gripper connected to one of the three mounting locations and at least one four point gripper connected to another one of the three mounting locations.
US09802324B2 Position detection sensor and manipulator
A position detection sensor includes: a linear member; a conductive portion and an insulating portion provided in an outer periphery of the linear member and arranged side by side in a direction of an axis of the linear member; a support member having insulating properties and provided so as to be capable of being relatively advanced or retracted in the direction of the axis with respect to the conductive portion and the insulating portion; and a conductive contact member attached to the support member and configured such that a distal end of the contact member comes in contact with outer surfaces of the conductive portion and the insulating portion by a biasing force toward the outer surfaces of the conductive portion and the insulating portion.
US09802318B2 Systems and methods for determining a status of a component of a device
Methods and systems for determining a status of a component of a device are provided. An example method includes triggering an action of a component of a device, and responsively receiving information associated with the action of the component from a sensor. The method further includes a computing system having a processor and a memory comparing the information with calibration data and determining a status of the component based on the comparison. In some examples, the calibration data may include information derived from data received from a pool of one or more devices utilizing same or similar components as the component. The determined status may include information associated with a performance of the component with respect to performances of same or similar components of the pool of devices. In one example, the device may self-calibrate the component based on the status.
US09802317B1 Methods and systems for remote perception assistance to facilitate robotic object manipulation
Methods and systems for remote perception assistance to facilitate robotic object manipulation are provided herein. From a model of objects in an environment of a robotic manipulator, a virtual boundary line separating two adjacent identified virtual objects may be identified. The robotic manipulator may be configured to perform a task involving a manipulation of at least one object in the environment represented by the identified virtual objects. Based on the identifying, a request for remote assistance with verifying the virtual boundary line may be sent to a remote assistor device. A response to the request, including a modification to the virtual boundary line, may then be received from the remote assistor device. The robotic manipulator may then be caused to perform the task based on the modification to the virtual boundary line.
US09802312B2 Operation command generation device, operation command generation method, non-transitory computer readable storage medium, and process system
Provided is an operation command generation device configured to generate an operation command, which is a collection of jobs to be carried out by a process system including a robot based on a protocol chart including a process symbol representing a process to be carried out on a container containing a process subject, the operation command generation device including: a process job generation unit configured to generate, based on the process symbol, a job for causing the process system to carry out the process on the container at a work area; and a transfer job generation unit configured to generate, when the process represented by the process symbol is not a process to be carried out on the same container, a job to transfer the container from the work area to a retreat area after the process represented by the process symbol has been carried out.
US09802310B2 Mobile robot estimating own position using a class-based own-position estimation unit
A robot is provided. A measurement unit measures an object in a space. An own-position estimation unit calculates an own position of a mobile unit moving through the space by matching measurement data acquired by the measurement unit with map data representing information about the object in the space. A classification unit acquires class-based measurement data obtained by classifying the measurement data into at least two predetermined classes. A class-based own-position estimation unit estimates an own position of the mobile unit for each of the at least two predetermined classes by matching a class-based map having a position of the objects recorded therein for each class with the class-based measurement data. An integration unit configured to integrate the own positions estimated for the respective at least two predetermined classes. A control unit controls the mobile unit based on information from the integration unit.
US09802309B2 Methods and systems for generating instructions for a robotic system to carry out a task
Example embodiments may relate to robot-cloud interaction. In particular, a cloud-based service may receive a query from a first robotic system including sensor data, a request for instructions to carry out a task, and information associated with a configuration of the first robotic system. The cloud-based service may then identify stored data including a procedure previously used by a second robotic system to carry out the task and information associated with a configuration of the second robotic system. The cloud-based service may then generate instructions for the first robotic system to carry out the task based at least in part on the sensor data, the procedure used by the second robotic system to carry out the task, the information associated with the configuration of the first robotic system, and the information associated with the configuration of the second robotic system.
US09802307B2 Locking intermediate link for a tool arm assembly
An intermediate link for a tool arm assembly is provided. The intermediate link includes first and second connectors that are at least partially rotatable about respective first and second rotation axes. The intermediate link includes first and/or second lock rotation mechanisms that are configured to selectively prevent rotation of the first and second connectors.
US09802303B2 Interface for fuel delivery system for combustion fastener driver
A fuel delivery system for use with a combustion fastener driver including a cylinder head frame, the system includes a fuel cell with an outer shell having a closed lower end and an open upper end, a closure crimped over the upper end and defining an opening for accommodating a reciprocating valve stem, a fuel cell adapter frictionally engaging the closure and including a flange configured for suspending the fuel cell in a tool fuel cell chamber. The adapter includes a collar configured for receiving the valve stem and being suspended for restricted vertical movement relative to the flange. A stem receiver block is connectable to the cylinder head frame and includes a stem engagement portion configured for directly and sealingly engaging an end of the valve stem, the stem engagement portion being in fluid communication with an internal receiver passage constructed and arranged for delivering fuel to a combustion chamber.
US09802301B2 Multi-head rack and pinion driven pulley puller
A multi-head, rack and pinion driven pulley puller including a rack and pinion drive assembly. The drive assembly includes a body member, a rack shaft, and a pinion gear, enclosed in the body member in one embodiment. The drive assembly further has a head that is adapted to receive a variety of puller assemblies, including a pivoting jaw puller assembly and a forked plate puller assembly.
US09802298B2 Electric ratchet wrench
An electric ratchet wrench includes a driving member rotatably mounted in a body. A pawl device is pivotably mounted to the driving member. A ring gear is rotatably mounted around the driving member. A flexible transmission shaft includes a first end connected to a motor and a second end configured to switch between a meshing state meshed with the ring gear and a disengagement state disengaging from the ring gear. The motor drives the transmission shaft to rotate the driving member. The body can be manually driven to overcome a resistance which is larger than the torque outputted by the motor and which causes a tooth slippage phenomenon between the transmission shaft and the ring gear.
US09802297B2 Tightening tool for a screw element having a line, and coupling part and screw element
Disclosed is a tightening tool for a screw element, having a tool receptacle and an associated line. A coupling part is provided, which is formed at a free end for engaging with the tool receptacle in a form-closed manner and transitions into a handle or can be coupled to a handle at the other end. The coupling part has an interior and at least one lateral opening for inserting or leading out the line at least at the free end of the coupling part. The interior and the opening extend to the free end and are open there. The invention further relates to a coupling part and to a screw element.
US09802287B2 System comprising a positioning and centering pin for an ophthalmic lens, an attachment member and a tool for positioning said attachment member on said positioning and centering pin
A system includes a positioning and centering pin (4) configured to be attached to an ophthalmic lens, an attachment member (5) configured to be positioned on and attached to the pin and to be attached to the lens, a tool (20) for positioning the attachment member on the pin, and which includes a body (42) provided with at least one receiving recess configured to at least partially receive at least one of the attachment members and the pin, at least one centering member (48, 56) and at least one guide member (48, 57), which are configured such that, when the attachment member and the pin are mounted on the tool, the attachment member is centered relative to the body and the pin is guided relative to the body, whereby the attachment member is positioned in a predetermined position on the pin.
US09802282B2 Fixtures for pipe installation, sealing and security
These fixtures aid in installing, sealing and securing pipe. Specifically, the invention aids in mating bell & spigot joints and securely capping open pipe ends of standard polyvinyl chloride (PVC), polyethylene (PE), and acrylonitrile-butadiene-styrene (ABS) pipe products as well as non-plastic piping by enabling equalized full circumference pressure on pipe ends to nudge, seal and/or secure pipe ends during installation or decommissioning.
US09802275B2 Rosin-free thermosetting flux formulations
Rosin-free thermosetting flux formulations for enhancing the mechanical reliability of solder joints. In accordance with one or more aspects, a solder paste as shown and described herein imparts improved or enhanced solder joint properties relating to at least one of drop shock, thermal cycling, thermal shock, shear strength, flexural strength performance, and/or other thermal-mechanical performance attributes.
US09802273B2 Method for manufacturing aluminum alloy cladding material
A first layer (11) and a second layer (12) are layered with an intermediate layer (21) therebetween. A clad material (1) is manufactured by heating and bonding the layered body at a temperature, at which the ratio of the mass of a liquid phase generated from the intermediate layer (21) is 5% or more and 35% or less, and by rolling the body. The clad material may comprise the clad material (1) which is a two-layer material formed of the first layer (11) and the second layer (12) as described above, as well as a third layer, a fourth layer, a fifth layer, and the like.
US09802266B2 Welding torch system for use in welding or cutting operations, welding torch for use in such a welding torch system and method for welding using such a welding torch system or such a welding torch
Welding torch system for use in welding or cutting operations during which fume is created. The welding torch system has a welding torch comprising a contact tip holder and a coaxial nozzle comprising an inner shield gas conduit having a shield gas outlet for supplying a shield gas. The inner shield gas conduit surrounds the contact tip holder. An outer shell at least partly surrounds said inner shield gas conduit. The welding torch system further comprises a shield gas generator and supply unit for supplying shield gas through the shield gas outlet and a fume extracting assembly for extracting fume and ambient air. The welding torch system is arranged for—during operation—supplying shield gas through the shield gas outlet at a velocity between about 1.5 m/s and 10 m/s. By operating the fume extracting assembly to generate a flow of between 10 and 100 m3/h, preferably a flow of about 55 m3/h a reduction in the area of 90%-95% of hazardous fumes can then be realized. A welding torch for use in such a system has an inner shield gas conduit having an end portion with an inner surface of which the diameter decreases towards the shield gas outlet. In a method for welding the shield gas is supplied through the shield gas outlet at a velocity between about 1.5 m/s and 10 m/s.
US09802259B2 Tool system for machining a workpiece
A tool system for machining a workpiece is provided having a cylinder-shaped retaining shank that has a cutting head holder on an end surface facing the workpiece, a drive mount on an end surface facing the drive, a cutting head having at least one cutting edge, a cutting head hub corresponding to the cutting head holder on the retaining shank, a tool coupling with a tool interface, and a coupling hub corresponding to the drive mount. The coupling hub or the cutting head hub have elevated areas, with contact surfaces, distributed in circumferential and longitudinal directions of the coupling hub or the cutting head hub. The contact surfaces make contact on support surfaces on the drive mount or on the cutting head holder on the retaining shank. The drive mount or the cutting head holder is permanently connected to the coupling hub or the cutting head hub by a joining material in intermediate spaces between the elevations.
US09802255B2 Rhombus-shaped reversible cutting insert and support seat therefor
An assembly of a generally rhombus-shaped reversible cutting insert and a support seat. Each end surface of the cutting insert has a corner abutment surface adjacent each nose cutting edge, at least one inner abutment surface on one side of a lateral plane, and at least one inner abutment surface on the opposite side of the lateral plane, and each corner abutment surface is located closer to a median plane than its adjacent nose cutting edge. In each index position of the cutting insert on the support seat, only one corner abutment surface is in operative contact with one of a plurality of protruding supporting members of the support seat, and only the at least one inner abutment surface located on the opposite side of the lateral plane from the operative corner abutment surface is in contact with the at least one remaining supporting member.
US09802251B2 Ni ball, Ni core ball, solder joint, solder paste, and solder foam
Provided are a Ni ball, a Ni core ball, a solder joint, solder paste and foamed solder which are superior in the impact resistance to dropping and can inhibit any occurrence of a poor joints. An electronic component 60 is constructed by joining a solder bump 30 of a semiconductor chip 10 to an electrode 41 of a printed circuit board 40 with solder paste 12, 42. The solder bump 30 is formed by joining an electrode 11 of the semiconductor chip 10 to the Ni ball 20. The Ni ball 20 according to the present invention contains purity which is equal to or higher than 99.9% and equal to or lower than 99.995%, sphericity which is equal to or higher than 0.90, and Vickers hardness which is equal to or higher than 20HV and equal to or less than 90HV.
US09802250B2 Magnesium alloy powder metal compact
A powder metal compact is disclosed. The powder metal compact includes a cellular nanomatrix comprising a nanomatrix material. The powder metal compact also includes a plurality of dispersed particles comprising a particle core material that comprises an Mg—Zr, Mg—Zn—Zr, Mg—Al—Zn—Mn, Mg—Zn—Cu—Mn or Mg—W alloy, or a combination thereof, dispersed in the cellular nanomatrix.
US09802248B2 Castings and manufacture methods
A method for casting an article comprises a first region and a second region. The method comprises casting an alloy in a shell, the shell having a casting core protruding from a first metal piece; and deshelling and decoring to remove the shell and core and leave the first region formed by the first piece and the second region formed by the casted alloy.
US09802245B2 Homogenization and heat-treatment of cast metals
A method of casting a metal ingot with a microstructure that facilitates further working, such as hot and cold rolling. The metal is cast in a direct chill casting mold, or the equivalent, that directs a spray of coolant liquid onto the outer surface of the ingot to achieve rapid cooling. The coolant is removed from the surface at a location where the emerging embryonic ingot is still not completely solid, such that the latent heat of solidification and the sensible heat of the molten core raises the temperature of the adjacent solid shell to a convergence temperature that is above a transition temperature for in-situ homogenization of the metal. A further conventional homogenization step is then not required. The invention also relates to the heat-treatment of such ingots prior to hot working.
US09802243B2 Methods for casting titanium and titanium aluminide alloys
The disclosure relates generally to mold compositions and methods of molding and the articles so molded. More specifically, the disclosure relates to mold compositions, intrinsic facecoat compositions, and methods for casting titanium-containing articles, and the titanium-containing articles so molded.
US09802242B2 Forging machine with robotic handler
A progressive cold forming machine and a robot for automatically changing a cutoff cassette, tooling cassettes, a transfer slide and transfer cam. A loading area adjacent the machine and robot has provisions for supporting a tooling cassette pallet and a transfer slide and camshaft pallet and a holding area for temporarily receiving some of the componentry being exchanged.
US09802241B2 Flat semi-finished product made of metal and methods for producing same as well as components thereof
The invention relates, in a first aspect, to a flat semi-finished product made of metal (1), wherein said semi-finished product comprises at least out structured section (2) and at least one non-structured section, wherein said semi-finished product has non-structured edge sections (4) and exhibits a high strength. The semi-finished product made of metal (1) according to the invention is characterized in that it is designed as one piece and predetermined sections (2) are structured and predetermined sections are non-structured, wherein at least one non-structured section (4) is designed as a connecting region for positive or non-positive connection or for connecting by bonding. Furthermore, methods for producing the semi-finished products according to the invention are provided.
US09802237B2 Head of an exploding-wire electrohydraulic discharge device
A head of an electrohydraulic discharge device of the invention comprises: —an end of a power cable having a first conductor and a second conductor, —an explosive wire comprising multiple segments assembled in a series, and —means for connecting each of the ends of the explosive wire to the end of the power cable.
US09802235B2 Method for producing a torsional profile from a blank, and torsional profile
The invention relates to a method for producing a torsional profile from a blank. The torsional profile has torsionally rigid tubular end sections, a torsionally flexible U-shaped middle longitudinal section and, between the middle longitudinal section and the end sections, transition sections which change from the U-shaped cross section to the tubular cross section.
US09802233B2 Gold evaporative sources with reduced contaminants and methods for making the same
A unique sequence of steps is provided to reduce contaminants along one or more surfaces and faces of gold evaporative sources without deleteriously impacting the structure of the gold evaporative sources. Edges are deburred; contaminants are successfully removed therealong; and surface smoothness is substantially retained. The resultant gold evaporative source is suitable for use in evaporative processes as a precursor to gold film deposition without the occurrence or a substantial reduction in the likelihood of spitting by virtue of significantly reduced levels of contaminants, in comparison to gold evaporative sources subject to a standard cleaning protocol.
US09802231B2 Bending and balancing device for axially shiftable work rolls of a rolling mill
The invention relates to a bending and balancing device for axially shiftable work rolls (10, 10′) of a rolling mill, especially of a four-high rolling mill, guide blocks (2) being provided at both sides in the window of every mill housing (1) on the level of the work roll inserts (3, 3′) and the force of bending and balancing cylinders (5) being transmissible onto the work roll inserts that are guided in the axial direction and so as to be shiftable in the vertical direction. The guide blocks are subdivided into respective upper and lower guide blocks (2, 2′), the upper guide blocks (2) are mounted in the mill housing window so as to be vertically shiftable, the lower guide blocks (2′) are mounted in the mill housing window so as to be fixed or so as to be vertically shiftable, and a bending and balancing cylinder (5) is arranged in every of the associated upper and lower guide blocks and is guided by the same and engages with the upper and the lower work roll insert.
US09802227B2 Method of cleaning substrate processing apparatus
A spin base is caused to rotate at a number of revolutions of from 250 rpm to 350 rpm (first number of revolutions), and at the same time, a cleaning solution is supplied through a discharge head to a holding surface of a spin base while the upper end of a processing cup surrounding the spin base is placed below the holding surface. Thus, an outer upper surface of the processing cup is cleaned with the cleaning solution scattered from the holding surface. Then, the spin base is caused to rotate at a number of revolutions of from 350 rpm to 450 rpm (second number of revolutions) higher than the first number of revolutions, and at the same time, a cleaning solution is supplied through the discharge head onto the holding surface. Thus, a partition plate outside the processing cup is cleaned with the cleaning solution scattered from the rotating holding surface.
US09802224B2 Ultrasound transducer device and method of manufacturing the same
The present invention relates to an ultrasound transducer device comprising at least one cMUT cell (30) for transmitting and/or receiving ultrasound waves, the cMUT cell (30) comprising a cell membrane (30a) and a cavity (30b) underneath the cell membrane. The device further comprises a substrate (10) having a first side (10a) and a second side (10b), the at least one cMUT cell (30) arranged on the first side (10a) of the substrate (10). The substrate (10) comprises a substrate base layer (12) and a plurality of adjacent trenches (17a) extending into the substrate (10) in a direction orthogonal to the substratesides (10a, 10b), wherein spacers (12a) are each formed between adjacent trenches (17a). The substrate (10) further comprises a connecting cavity (17b) which connects the trenches (17a) and which extends in a direction parallel to the substrate sides (10a, 10b), the trenches (17a) and the connecting cavity (17b) together forming a substrate cavity (17) in the substrate (10). The substrate (10) further comprises a substrate membrane (23) covering the substrate cavity (17). The substrate cavity (17) is located in a region of the substrate (10) underneath the cMUT cell (30). The present invention further relates to a method of manufacturing such ultrasound transducer device.
US09802221B2 Deposition mask production method and laser processing apparatus
A method including: a first step of forming a mask member having a structure in which a magnetic metal member provided with through-holes is in tight contact with one surface of a film; a second step of forming a plurality of preliminary opening patterns by subjecting the film to penetration processing by irradiating laser beams at predetermined regular positions in the plurality of through-holes; and a third step of performing laser processing so as to form each opening pattern over the corresponding preliminary opening pattern, is provided.
US09802220B2 Molybdenum (IV) amide precursors and use thereof in atomic layer deposition
Molybdenum (IV) amide complexes are disclosed herein corresponding in structure to Formula (I): wherein: L is —NR1R2; R1 and R2 are C1-C6-alkyl or hydrogen; R is C1-C6-alkyl; and n is zero, 1, 2 or 3. Further, methods of forming MoO2 films by atomic layer deposition (ALD) using Formula (I) complexes and Mo[N(Me)(Et)]4 are disclosed herein.
US09802219B2 Polymer workpiece for flow coating
A polymer workpiece is described. The workpiece has an upper main surface, a lower main surface, an injection-mold separating surface and a flow attack edge surface. The flow attack edge surface is formed in the region between the injection-mold separating surface and the lower main surface as a planar surface with an angle α with respect to the injection-mold separating surface of 20° to 70°, and/or deviates by an amount a from 0.0 mm to 0.5 mm from the planar surface.
US09802216B2 Automated stent coating apparatus and method
An automated apparatus and method for coating medical devices such as an intravascular stent, are disclosed in the method, a 2-D image of a stent is processed to determine (1) paths along the stent skeletal elements by which a stent secured to a rotating support element can be traversed by a dispenser head whose relative motion with respect to the support element is along the support-element axis, such that some or all of the stent skeletal elements will be traversed (2) the relative speeds of the dispenser head and support element as the dispenser head travels along the paths, and (3), and positions of the dispenser head with respect to a centerline of the stent elements as the dispenser head travels along such paths The rotational speed of the support and relative linear speed of the dispenser are controlled to achieve the desired coating thickness and coating coverage on the upper surfaces, and optionally, the side surfaces, of the stent elements.
US09802215B2 Method and system for applying a coating
A method and apparatus are presented. A first roller has a sensor that senses a speed of the workpiece while the workpiece is in contact with the first roller and moving relative to the first roller causing the first roller to rotate. The sensor senses the speed of the workpiece from a rotation of the first roller. A second roller causes the sealant on the second roller to be applied to a surface of the workpiece when the workpiece is in contact with the second roller and moving relative to the second roller. The second roller is rotationally linked to the first roller. A third roller causes the sealant on the surface of the workpiece to spread on the surface when the workpiece is in contact with the third roller and moving relative to the third roller. The third roller is rotationally linked to the second roller.
US09802213B2 Spray gun having internal boost passageway
A barrel (20) adapted for use with a spray gun (2) is disclosed. The barrel (20) comprises a boost feed port (44) fluidly connected to a boost passageway (48), the boost passageway (48) being integral to the barrel (20). The boost passageway (48) is adapted to convey a pressurized boost fluid originating in the spray gun (2) to a boost delivery port (56) to assist in urging a coating fluid from a compatible coating fluid reservoir (80) for spraying by the spray gun (2).
US09802208B2 Centrifugal rotor with arc-shaped centrifugal carrier or weight body
A centrifugal rotor includes a support disk and a centrifugal carrier. The centrifugal carrier is assembled within the support disk. The centrifugal carrier includes an arc-shaped body, a sample application chamber, a sample metering chamber, a diluent chamber, a diluent metering chamber, a metering control member and a mixing chamber. The sample metering chamber is communicated with the sample application chamber. The sample metering chamber is positioned radially outward from the sample application chamber. The diluent metering chamber is communicated with the diluent chamber. The diluent metering chamber is positioned radially outward from diluent chamber. The metering control member is slidingly connected within or detachably fixed to the sample metering, chamber or the diluent metering chamber. The mixing chamber is communicated with the diluent metering chamber and the sample metering chamber respectively. The mixing chamber is positioned radially outward from both the diluent metering chamber and the sample metering chamber.
US09802207B2 Air conditioning apparatus
Provided is an air conditioning apparatus. The air conditioning apparatus includes a main body having a suction part through which air is suctioned and a discharge part through which the air suctioned through the suction part is discharged, a fan disposed within the main body to allow the air to flow, a filter device disposed between the suction part and the discharge part within the main body, the filter device including a filter including a plurality of arrays that are spaced apart from each other, and a power supply part to supply a voltage to each of the arrays. Each of the arrays includes a conductive member, the conductive member contacts a dielectric containing a dielectric material.
US09802206B2 Method for producing graphene
A dispersion of suspended single-layer graphene, multilayer graphene, and graphite is used. A magnetic field is applied to the dispersion to separate the single-layer graphene from the dispersion. By applying the magnetic field, the single-layer graphene, the multilayer graphene, and the graphite are situated at different locations in solvent by the difference in the diamagnetism strengths of the single-layer graphene, the multilayer graphene, and the graphite.
US09802199B2 Fluorescence detector for microfluidic diagnostic system
The present technology provides for a fluorescent detector that is configured to detect light emitted for a probe characteristic of a polynucleotide. The polynucleotide is undergoing amplification in a microfluidic channel with which the detector is in optical communication. The detector is configured to detect minute quantities of polynucleotide, such as would be contained in a microfluidic volume. The detector can also be multiplexed to permit multiple concurrent measurements on multiple polynucleotides concurrently.
US09802198B2 Valve device
A recess 22 provided in a passage block 20; a diaphragm covering the recess 22 to form a valve chest 21 in which a fluid flows; an inflow port 23 opened at the recess 22 and allowing the fluid to flow into the valve chest 21; an NC outflow port 24 and an NO outflow port 25 opened at the recess 22 and allowing the fluid to flow out from the valve chest 21; by oscillating the diaphragm, the diaphragm is closely fitted to any one of a first valve seat 24b formed by an opening 24a of the NC outflow port 24 and a second valve seat 25b formed by an opening 25a of the second outflow port 25, to allow the fluid in the valve chest 21 to flow out from the other outflow port. The recess 22 has a first inclined portion 81 and a second inclined portion 82 having a depth gradually increasing from the first valve seat 24b and the second valve seat 25b toward the inflow opening 23.
US09802193B2 System and method for capturing and analyzing cells
A system and method for capturing and analyzing cells comprising: a fluid delivery module; a reservoir configured to receive a biological sample including a target cell population and at least one fluid from the fluid delivery module; a manifold configured to receive and distribute the biological sample and at least one fluid from the reservoir into a cell capture device; a waste chamber configured to couple to the manifold; and a pump configured to couple to the waste chamber. In embodiments of the system configured to promote further purification of captured cells, the system can further comprise a magnet that enables further separation of captured cells from undesired sample materials. The system can additionally further comprise a heater configured to heat at least one fluid and/or biological sample, and a cell capture device configured to couple to the manifold, in order to facilitate capture of the target cell population.
US09802192B2 Sorting chamber for microscale particles
A sorting chamber (1) for sorting first particles (25) from second particles (26) comprising: an internal chamber (7), which is delimited by a base wall (2), a top wall (4), and a spacer (6), set between the base wall (2) and the top wall (4); an internal chamber (7), which is at least partially-delimited by the base wall (2) and top wall (4); two passages (8), which set in communication the internal chamber (7) with the external environment; and a plurality of cavities (9), which are designed to house the first particles (25), are made in the base wall (2) and have openings (10) towards the internal chamber (7) with widths of from 4 to 6 μm.
US09802191B2 Disposable, fluid actuated, mechanically driven point-of-care invitro-diagnostic apparatus and method of performing a point-of-care invitro-diagnostic test
A portable, disposable in-vitro diagnostic apparatus and method of performing a point-of-care invitro-diagnostic test is provided. The apparatus has a body with at least one chamber containing an actuator member. The chamber is in fluid communication with an upstream first fluid channel and a downstream second fluid channel. The actuator member has a compressed, deactivated state and an expanded, activated state. The actuator member transitions from the compressed, deactivated state to the expanded, activated state upon contact with fluid flowing through the first fluid channel. The actuator member pumps fluid outwardly from the first chamber through the second fluid channel during the transition from its compressed, deactivated state to its expanded, activated state. The pumped fluid can be channeled to other chambers within the body and/or to an analysis chamber within the body for study.
US09802190B2 Modular computer-controlled multistep chemical processing system for use in laboratory automation or chemical production spanning a plurality of scales
A modular laboratory-style computer-controlled system for multistep chemical processing for use in laboratory automation or chemical production is disclosed. The system comprised a plurality of interconnectable electrically-powered controllable chemical process modules having chemical input and output ports and at least one communications interface. Interconnection among the chemical process modules include both chemical flow interconnections for the transport of chemical materials and network interconnections for the transport of communications signals. In some implementations chemical flow interconnections are software controllable.
US09802189B2 Density phase separation device
A mechanical separator for separating a fluid sample into first and second phases within a collection container is disclosed. The mechanical separator may have a separator body having a through-hole defined therein, with the through-hole adapted for allowing fluid to pass therethrough. The separator body includes a float, having a first density, and a ballast, having a second density greater than the first density. A portion of the float is connected to a portion of the ballast. Optionally, the float may include a first extended tab adjacent a first opening of the through-hole and a second extended tab adjacent the second opening of the through-hole. In certain configurations, the separator body also includes an extended tab band disposed about an outer surface of the float. The separator body may also include an engagement band circumferentially disposed about at least a portion of the separator body.
US09802187B2 Non-woven electret fibrous webs and methods of making same
A non-woven electret fibrous web for electrostatic adsorption and odor elimination and the preparation process thereof. In certain exemplary embodiments, the non-woven electret fibrous web includes a multiplicity of electret fibers, at least one of a plurality of photo-catalytic fibers or a plurality of multi-component fibers; and optionally, at least one of a plurality of chemically-active particulates, a plurality of carbon-based fibers, or a plurality of mono-component thermoplastic fibers. In other exemplary embodiments, carding and cross-lapping or air-laying processes are disclosed for making nonwoven fibrous webs including electret fibers and one or more of photocatalytic fibers, chemically-active particulates, multi-component fibers, mono-component thermoplastic fibers, or carbon-based fibers. In some exemplary embodiments, exemplary non-woven electret fibrous webs of the disclosure exhibit superior gas permeation characteristics, high adsorption characteristics for airborne contaminants, as well as an odor elimination function.
US09802181B2 Catalyst system and use in heavy aromatics conversion processes
Disclosed are a catalyst system and its use in a process for the conversion of a feedstock containing C8+ aromatic hydrocarbons to produce light aromatic products, comprising benzene, toluene and xylene. The catalyst system comprises (a) a first catalyst bed comprising a first catalyst composition, said first catalyst composition comprising a zeolite having a constraint index of 3 to 12 combined (i) optionally with at least one first metal of Group 10 of the IUPAC Periodic Table, and (ii) optionally with at least one second metal of Group 11 to 15 of the IUPAC Periodic Table; and (b) a second catalyst bed comprising a second catalyst composition, said second catalyst composition comprising (i) a meso-mordenite zeolite, combined (ii) optionally with at least one first metal of Group 10 of the IUPAC Periodic Table, and (iii) optionally with at least one second metal of Group 11 to 15 of the IUPAC Periodic Table, wherein said meso-mordenite zeolite is synthesized from TEA or MTEA and having a mesopore surface area of greater than 30 m2/g and said meso-mordenite zeolite comprises agglomerates composed of primary crystallites, wherein said primary crystallites have an average primary crystal size as measured by TEM of less than 80 nm and an aspect ratio of less than 2.
US09802179B2 Method for processing an edge of catalyst-supporting honeycomb structure in exhaust gas denitration apparatus
A method for processing an edge of a catalyst-supporting honeycomb structure in an exhaust gas denitration apparatus, in which an exhaust gas denitration apparatus equipped with a denitration catalyst-supporting honeycomb structure in which a corrugated plate-like inorganic fiber sheet and a flat plate-like inorganic fiber sheet, each supporting thereon a denitration catalyst containing a silica sol, titania particles, and ammonium metavanadate as a whole primary denitration catalyst layer, are alternately laminated, the edge of gas inlet side of the denitration catalyst-supporting honeycomb structure having the whole primary denitration catalyst layer is dipped in a denitration catalyst-containing slurry for edge processing composed of a silica sol, titania particles or kaolin particles, and ammonium metatungstate to form a coating layer of the denitration catalyst-containing slurry in the edge of the honeycomb structure, and this is dried and then calcinated to form an edge secondary denitration catalyst layer.
US09802176B2 Method for mixing in a hydrocarbon conversion process
A sequential mixer for mixing a heated hydrocarbon stream and a supercritical fluid to produce an intimately mixed stream upstream of a supercritical reactor. The sequential mixer comprising a body having a body length and a body diameter; a hydrocarbon inlet physically connected to the body, having an inlet diameter, the heated hydrocarbon stream is introduced through the hydrocarbon inlet; a mixed stream outlet physically connected to the body and fluidly connected to the supercritical reactor, having an outlet diameter; a traversing axis extending through the center of the body from the hydrocarbon inlet to the mixed stream outlet; and a plurality of fluid ports physically connected to the body, the plurality of fluid ports are arranged in a port alignment arrayed along the traversing axis, each fluid port has a port diameter and a port angle, the supercritical fluid is injected through the plurality of fluid ports.
US09802167B2 Turbo jet mixer
A tank cleaning machine comprising a housing having an inlet and a stationary guide diverter disposed within the housing. A gearing mechanism is attached to the stationery flow diverter. A nozzle extends from the housing wherein the nozzle is in fluid communication with the inlet and the nozzle includes an inclined portion extending from a horizontal portion of the nozzle. A drag limiter extends into a hydraulic fluid reservoir to limit the rotation speed of the gear.
US09802165B2 3D expanding geometry
This invention relates to bubble generation, in particular to microbubble generation in a microfluidic device, which bubbles may be useful as contrasting agents or drug delivery vehicles. The invention further relates to apparatuses, systems and methods for manufacturing said microbubbles, microbubbles produced by such methods and to their uses, e.g. in medical, diagnostic and other such applications. The microbubbles are preferentially formed using a microspray regime.
US09802159B2 Air separation module canister
An air separation module includes a housing, an air separation element, and an insulating element. The housing has an inlet and two outlets. The air separation element is enclosed within the housing and extends along a length of the housing. The insulating element is positioned inward of an outer perimeter of the housing and substantially surrounds an outer perimeter of the air separation element along a length of the air separation element.
US09802158B2 Ultrafiltration membrane device, bioartificial organ, and related methods
The present invention relates to ultrafiltration. In particular, the present invention provides nanoporous membranes having pores for generating in vitro and in vivo ultrafiltrate, devices and bioartificial organs utilizing such nanoporous membranes, and related methods (e.g., diagnostic methods, research methods, drug screening). The present invention further provides nanoporous membranes configured to avoid protein fouling with, for example, a polyethylene glycol surface coating.
US09802150B2 Carbon dioxide absorbent based on amine having nitrile functional group, and carbon dioxide absorption method and separation method using same
The present invention relates to a method for using, as a carbon dioxide absorbent, a secondary amine having a nitrile group, that is, a 3-(alkylamino)propionitrile compound. The absorbent based on the 3-(alkylamino)propionitrile compound and the carbon dioxide absorption method and separation method using same, according to the present invention, not only have an excellent carbon dioxide absorption capacity and a rapid carbon dioxide absorption rate, but also allow absorbent regeneration even at a considerably low temperature compared with a conventional alkanolamine-based absorbent and thus can significantly reduce the entire energy consumption required for an absorption process, and can also prevent recovered carbon dioxide from being contaminated with moisture and absorbent vapor, owing to the low regeneration temperature.
US09802149B1 Sorbent-based atmosphere revitalization system
The present invention is a sorbent-based atmosphere revitalization (SBAR) system using treatment beds each having a bed housing, primary and secondary moisture adsorbent layers, and a primary carbon dioxide adsorbent layer. Each bed includes a redirecting plenum between moisture adsorbent layers, inlet and outlet ports connected to inlet and outlet valves, respectively, and bypass ports connected to the redirecting plenums. The SBAR system also includes at least one bypass valve connected to the bypass ports. An inlet channel connects inlet valves to an atmosphere source. An outlet channel connects the bypass valve and outlet valves to the atmosphere source. A vacuum channel connects inlet valves, the bypass valve and outlet valves to a vacuum source. In use, one bed treats air from the atmosphere source while another bed undergoes regeneration. During regeneration, the inlet, bypass, and outlet valves sequentially open to the vacuum source, removing accumulated moisture and carbon dioxide.
US09802147B2 Filter tube for high temperature gas-solid separation
A filter tube for high temperature gas-solid separation is provided that has a first cylinder and a second cylinder coaxially nested in the first cylinder with the first cylinder arranged so that an opening thereof faces upward, a first connection flange provided at a periphery of the opening of the first cylinder, and a circular through-hole provided at a bottom of the first cylinder. The second cylinder is nested in the first cylinder so that an opening of the second cylinder faces downward. The second cylinder has an end at an opening thereof that is hermetically connected to the circular through-hole of the first cylinder. The second cylinder has a bottom, and the bottom of the second cylinder and the opening of the first cylinder are at the same horizontal level. An annular gas passage is formed between the first cylinder and the second cylinder.
US09802143B2 Ceramic filter
A ceramic filter is provided with a porous substrate 3 “made of ceramic and having partition walls 1 separating and forming a plurality of cells 2 extending from one end face 11 to the other end face 12”, a separation membrane 21 “made of ceramic and disposed on wall surfaces of the cells 2”, and glass seals 31 disposed on the one end face 11 and on the other end face 12 “so as not to cover openings of the cells 2”. Ceramic particles having a thermal expansion coefficient of 90 to 110% of that of glass contained in the glass seals 31 are dispersed in the glass seals 31. There is provided a ceramic filter usable for a long period of time in high temperature conditions.
US09802142B2 Purifier cassette
The present disclosure relates to purification cassettes that have reinforcing features. One embodiment relates to a purification cassette with tensions members. A purification system may include a removable cassette defining a media cavity. A set of tension members may span between a first sidewall and second sidewall. The set of tension members can divide the media cavity into a plurality of lanes.
US09802141B1 Cleaning system for filter beds
A cleaning system for filter beds uses the existing permanent infrastructure of a water filtration plant. Treatment fluids of opposite pH are introduced into a pair of filter cells that are separated by a gullet. Each filter cell contains a filter bed. One filter cell receives an acidic treatment fluid and the other receives an alkaline treatment fluid. After treatment is complete, the treatment fluids from each filter cell are simultaneously drained into the gullet, where mixing and neutralization occur. The resulting spent treatment fluid has an intermediate pH that allows it to be safely drained into a wastewater sewer.
US09802133B2 Floating sheet wave water attraction
A sheet wave water attraction includes a buoyant structure adapted for floating on a naturally occurring body of water, a sheet wave generator mounted to the structure, and a wave-forming ramp on the structure cooperating with the wave generator for the formation of waves on the ramp. The wave generator has a water intake below a waterline on the structure. The intake is configured to draw water from the body of water adjacent the structure. The buoyant structure has a shallow draft, including the draft of a water intake for the wave generator whereby near-coastal off-shore positioning may be achieved for operationally positioning the water attraction close to shore.
US09802131B2 Amusement ride for hang gliding simulation
An amusement ride includes a plurality of main arms which are moved by at least one motor along a circular path about a central rotation axis arranged substantially vertical to the ground, or to a platform. The main arms are rotatable about a rotation axis so that a first portion, which extends with respect to the rotation axis, can be raised or lowered with respect to the ground. The ride further includes at least one seat for at least one rider connected to the first portion of the main arm, at least one movable aerodynamic surface, and a control device for modifying the angle of incidence of the aerodynamic surface with respect to the air flow impacting it during the rotation of the main arm about the central axis.
US09802127B2 Video game including user determined location information
A method, apparatus and computer program product for a video game including user determined location information is presented. Location information (e.g. GPS, Google Maps, an entered address or the like) determined by a user of a video game is acquired. Then user determined location information relating to a physical location determined by the user is mapped to a video game environment wherein the user of the video game experiences objects from the users entered location while playing the video game.
US09802125B1 On demand guided virtual companion
A first user of a first device may interact with a character presented on the first device where the character presented on the first device is guided by a second user of a second device. To begin a communications session, the first user may request to communicate with the character. A server may process the request to speak with the character and identify the second user from a plurality of guiding users, where the second user is identified by comparing profile information of the first user with profile information of the second user. The server may then send a request to the second device of the second user to guide the character presented by the first device. The first user may then communicate with the character with the guidance of the second user.
US09802118B2 Game controller with clamp for portable device
A game controller for use with handheld game devices, for example smartphones, includes a cradle for holding the smartphone. The cradle is pivotable between an open position, extending from a base of the game controller, and a closed position in which the cradle is about a bottom wall of the base.
US09802116B2 Machine learning controller for prize dispensing entertainment machines
A system to rapidly set up new claw machines for different styles of prizes, while also providing an excellent player experience through dynamically changing claw machine behavior through machine learning algorithms. These systems can be readily installed on most any crane machine by replacing the controller card. The system is configured by means of a control wand physically connected to the controller. Teaching the machine about the prize is accomplished by physically inserting a sample prize into the grabber, and executed a command via control wand to tell the machine to learn. Once configured and taught the prize, the machine is autonomous, and will maintain its programmed profit margin throughout the prizes dispensed by learning player behavior and making adjustments after each play.
US09802113B2 Portable shuffling device
A shuffling device (1) includes cards (2) containing information for determination of proper/improper, card set trays (3) for placing the cards (2), and a common card stocker (4) for stocking cards drawn out from the card set trays (3). Drawing rollers (5,6) are provided below the card set trays (3) to draw out the cards (2) from the card set trays (3) to the card stocker (4). A control device (8) includes number-of-cards determining means for determining a number of cards to be drawn out by randomly changing, each time, the number of cards to be drawn out at one time within a range of a predetermined value, and controlling the drawing means, where the cards (2) are drawn out from only one of the card set trays (3) such that the cards (2) are not simultaneously drawn out from more than one of the card set trays (3).
US09802111B2 Stroker's aid and method of using the same
A device that is configured to be usable to assist a user in moving a cue member (e.g. a pool cue or cue stick) that is sized and configured to strike a ball for a game of pool or billiards can include a stabilizer element, a ring element attached to the stabilizer element, and a rest defining a first aperture along which a cue stick or other cue member is slideable. A method of using the device is configured so that the device can be used for hitting a ball in a game of pool or billiards by sliding a cue member along an aperture defined by the rest.
US09802107B2 Kart with movable visual effect
A ridable kart having a front portion rotatably coupled to a rear portion. The front portion includes an inner surface that is adjacent to an outer cover portion and the two surfaces move relative to one another. The outer cover portion includes window portions or openings through which a portion of the inner surface is visible. The inner surface includes a visual feature that is visible through the window portions and the visual features moves relative to the window portions when the front portion rotates relative to the rear portion.
US09802104B2 Reticulated digit shield for protective sports glove
A protective digit shield for a protective sports glove, the shield having a hard chassis portion and an energy absorbing portion forming a hinge. The chassis portion provides an arcuate channel in which the thumb/digit is received. The chassis is segmented along the longitudinal axis to provide a proximal portion and a distal portion corresponding generally with the proximal and distal phalanx bones of the thumb/digit. A resilient, energy absorbing element along the channel provides separation between the chassis and forms a living hinge such that the chassis can rotate. The energy absorbing element may also include a damping element along opposing edges at the segmented joint to absorb and dissipate forces and prevent hyperextension. In an alternate embodiment, the energy absorbing element is replaced with a connection cable for connecting the portions of the chassis.
US09802103B2 Protective equipment
A protective apparatus comprising a cantilever yoke system including a left arch slot, a right arch slot and one or more swivel slots, a left distal arch including attachment points configurable with the left arch slot of the cantilever yoke system, a left proximal arch including attachment points configurable with at least one of the attachment points of the left distal arch to join the left proximal arch to the left distal arch, a right distal arch including attachment points configurable with the right arch slot of the cantilever yoke system, a right proximal arch including attachment points configurable with at least one of the attachment points of the right distal arch to join the right proximal arch with the right distal arch, and a swivel including proximal arch slots configurable to join the left proximal arch with the right proximal arch.
US09802102B2 Electronic tracking system with heads up display
An electronic tracking system is disclosed for assisting a user in determining distances to objects in a sporting environment. The system includes a user tracking system for determining the location of a user, a heads up display for displaying information to the user, and a processor operable to communicate with the user tracking system and heads up display. The heads up display is designed to be worn by the user, and to display images within the user's field of view. The processor is programmed to determine a distance between the user's determined location and an object, such as a ball, located within the sporting environment. This information is displayed via the heads up display as a numeric representation of the determined distance. If tracking a ball, the heads up display may display an object indication, such as an enhanced image or a comet tail, superimposed over or adjacent the ball.
US09802097B2 Swing training system and method
A swing training system includes a base unit having a grapple that is movable between open and closed positions. A free end of an elongated swing device, such as a golf club or a hockey stick, is secured within the grapple. The swing device is manipulated to exert a force on the grapple and a load cell, away from the base unit, for a predetermined value, such as force and/or time. Relative movement between the grapple and the base is substantially limited while the swing device is manipulated. Once the predetermined value is attained, the grapple releases the free end of the swing device.
US09802092B2 Golf club cleaning device
A golf club cleaning device for cleaning golf clubs includes a panel that comprises cloth. A slot is positioned adjacent to a bottom edge of the panel. A plurality of first fasteners is coupled to a front of the panel adjacent to a fringe of the slot. A housing that is complementary to the slot has a plurality of bristles that is coupled to and extends transversely from a back face of the housing. The bristles are configured to engage a face of a golf club to dislodge debris. A plurality of second fasteners, which is complementary to the first fasteners, is coupled to and extends outwardly from a rim of the back face of the housing. The second fasteners are positioned to reversibly couple with the first fasteners to secure the housing to the panel.
US09802091B2 Golf club
A golf club head includes a club body including a heel portion, a sole portion, a toe portion, a top-line portion, and a face portion. In some embodiments, the face portion has an ideal striking location and at least one channel defined in the face. In some embodiments, the golf club head has a striking face and at least one channel defined in the striking face. In some embodiments, the golf club head has an ideal striking location and at least one non-ideal striking location.
US09802085B2 Golf club assembly and golf club with aerodynamic features
A golf club head includes a body member having a ball striking face, a crown, a toe, a heel, a sole, a rear, and a hosel region. The heel includes an airfoil-like surface shaped like the leading edge of an airfoil that extends over a majority of the length of the heel. The back may include a Kammback feature having a concavity extending from the heel-side to the toe-side of the back. The heel-side edge of the concavity may be shaped like the leading edge of an airfoil. Further, the sole may include a diffuser that extends at an angle of from approximately 10 degrees to approximately 80 degrees from a moment-of-impact trajectory direction. A hosel fairing that extends from the hosel region toward the toe may also be provided on the crown. A golf club including the golf club head is also disclosed.
US09802084B2 Golf club head
A golf club head comprises: a head main body having a hollow therein; a weight member disposed in the hollow and extending from its first end to its second end; a first end side portion of the weight member is secured to a first position of the head main body rotatably around a first axis at the first position so that a second end side portion of the weight member is movable to at least a second position and a third position of the head main body which positions are on a locus described by the first end side portion of the weight member during rotating about said first axis; and a fastener for fixing the second end side portion of the weight member to any of said at least second and third positions of the head main body.
US09802082B1 Textured sports ball
The sports ball (410) has an inner layer (416) and an outer panel (414). The inner layer (416) is secured to the outer panel (414) and several inner layers (416) and outer panels (414) are sewn together to form the sports ball (410). A strip (440) is positioned between the inner layer (416) and outer panel (414) under a white stripe (448) to raise the white stripe (448) on the sports ball (410) above the surrounding outer surface of the sports ball (410) to enhance grip. The sports ball (410) can be a football (412). A line of thread (424) can be stitched between the inner layer (416) and outer panel (414) on either side of the stripe (448) to enhance the shape retention of the sports ball (410), enhance grip and help keep the strip (440) in place. In a modification, a strip (480) is positioned between the inner layer (416) and outer panel (414) except under the white stripe (448) to form a void under the stripe (448) and enhance grip.
US09802081B2 Bike system for use in rehabilitation of a patient
A system for use in rehabilitation of a target patient is provided. The system includes at least two bicycle devices for use by the target patient and a second operator other than the target patient. The at least two bicycle devices each include pedals. At least one of the pedals may have at least one sensor mounted thereon for monitoring operation of the first bicycle device and the target's condition. A servomotor is coupled to the pedals for providing gear-like resistance or pedal assistance for the at least two bicycle devices. A controller is programmed to electrically couple the at least two bicycle devices to each other.
US09802079B1 Resistance breathing device
A resistance breathing device includes a face mask having a perimeter and an aperture extending therethrough, and being adapted to overlay a user's mouth and nose such that the perimeter forms an air-tight seal with the user's face. An overlaying outer layer has a pair of straps for affixing the face mask about the user's face. An adjustment slide is positioned adjacent the face mask, has an inlet aperture extending therethrough, and is movable between a first position in which a first portion of the inlet aperture overlaps the inlet aperture of the face mask and a second position in which a larger second portion of the inlet aperture overlaps the inlet aperture of the face mask. An adjustment wheel is attached to the face mask and is movable rotatably between first and second positions to cause the adjustment slide to move between its first and second positions.
US09802069B2 Throwable fire extinguisher
There is provided a fire extinguisher comprising a fire extinguishing agent; a first mechanism configured to operate said fire extinguisher via a manual operation; a second mechanism configured to operate said fire extinguisher automatically; and wherein said fire extinguisher comprises at least one detector to detect the existence of a fire and cause the operation of said second mechanism.
US09802067B2 Harness configurations for a suspension device
A harness system for harnessing a user to a suspension device. The harness comprises a strap system having a plurality of straps configured and operable to connect the suspension device to a back region of the harness, each strap having a back end portion at said back region and connectable to the suspension device, and a front end portion located in a front side of the harness. The straps extend from the back region to the front side of the harness and wrap around all sides of a torso of said user. A single connector assembly is used for quick connection of front end portions of at least some of the straps at the front side of the harness in a single interlocking operation, thereby to secure the harness to the user.
US09802066B2 Modular turnout gear
A modular garment includes a sleeved jacket and a vest that may be worn by a first responder. The sleeved jacket is constructed for use in some emergency circumstances, including technical rescue operations. Portions of the jacket, including at least portions of the sleeves, may be constructed to satisfy more stringent garment standards, such as garment standards for structural firefighting. A vest may be worn over the sleeved jacket to produce a combined jacket suitable for use as turnout gear in structural firefighting.
US09802063B2 Reflective ultrasound technology for dermatological treatments
Embodiments of a dermatological cosmetic treatment and imaging system and method can include use of transducer and a reflective surface to simultaneously produce multiple cosmetic treatment zones in tissue. The system can include a hand wand, a removable transducer module, a control module, a graphical user interface and/or a parabolic reflector. In some embodiments, the cosmetic treatment system may be used in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the décolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided.
US09802058B2 Central base coils for deep transcranial magnetic stimulation
A transcranial magnetic stimulation coil which is location-specific for medial brain regions or lateral brain regions is designed with multiple spaced apart stimulating elements having current flow in a first direction, and multiple return elements having current flow in a second direction which is opposite the first direction. The multiple stimulating elements are distributed around a central axis of the coil.
US09802054B2 Biostimulator circuit with flying cell
A leadless cardiac pacemaker is provided which can include any number of features. In one embodiment, the pacemaker can include a tip electrode, pacing electronics disposed on a p-type substrate in an electronics housing, the pacing electronics being electrically connected to the tip electrode, an energy source disposed in a cell housing, the energy source comprising a negative terminal electrically connected to the cell housing and a positive terminal electrically connected to the pacing electronics, wherein the pacing electronics are configured to drive the tip electrode negative with respect to the cell housing during a stimulation pulse. The pacemaker advantageously allows p-type pacing electronics to drive a tip electrode negative with respect to the can electrode when the can electrode is directly connected to a negative terminal of the cell. Methods of use are also provided.
US09802047B2 Method and apparatus for the treatment of focal dystonia
A method and apparatus for using low levels of electrical stimulation to treat focal dystonia by stimulating the afferent nervous system and/or altering the function of the gamma motor neurons innervating muscles which experience symptomatic spasms.
US09802046B2 Non-regular electrical stimulation patterns for improved efficiency in treating Parkinson's Disease
Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency. The systems and methods for stimulation of neurological tissue may be used to increase the efficacy of treatment in patients with Parkinson's Disease.
US09802045B2 Method for measuring stable and reproducible electrode-tissue impedance
The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
US09802044B2 System and method for neural hearing stimulation
A system for stimulation of a patient's ipsilateral cochlea, having at least two spaced apart patient-worn microphones for providing first and second audio signals from ambient sound; a sound processor for generating an ipsilateral auditory nerve stimulation signal in a plurality of output channels from at least one of the input audio signals; and a stimulation assembly for being implanted within the ipsilateral cochlea and having a plurality of stimulation channels for ipsilateral stimulation of the patient's hearing according to the ipsilateral auditory nerve stimulation signal. The sound processor comprising a DOA unit for determining periodically a main direction of incidence of ambient sound from a sound source by analyzing the first and second audio signals, and a directional information coding unit for coding information concerning the determined main direction of incidence in the ipsilateral auditory nerve stimulation signal in manner to enable the patient to localize the sound source.
US09802041B2 Systems for peripheral nerve stimulation to treat tremor
A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.
US09802040B2 Body motion detection device and human body stimulation apparatus comprising said device
The human body stimulation apparatus comprises a left detection unit, a right detection unit, a determination unit, a control unit, a right stimulation unit and a left stimulation unit. The detection units generate a detection signal according to a walking motion of a human body. The determination unit divides the walking motion of one walking cycle into multiple walking stages on the basis of the detection signal. The determination unit determines that the walking motion is stopped on the basis of at least one duration time of the walking stages. The control unit controls the magnitude of the stimulation that the right stimulation unit and the left stimulation unit apply to the human body on the basis of the determination results of the determination unit.
US09802039B2 Electrical stimulation device and method for the treatment of neurological disorders
An electrical stimulation system and method for the treatment of neurological disorders is disclosed. In a preferred embodiment, the electrical stimulation system includes channels of electrodes positioned in electrical contact with tissue of a neuromuscular target body region of a patient to provide pattered neuromuscular stimulation to the patient's musculature. In addition, at least one electrode from a channel is positioned in electrical contact with a tissue of the motor control region of the brain. A series of patterned electrical pulses are then applied to the patient through the channels to provide peripheral neuromuscular stimulation, and a direct current is applied transcranially to the brain. Various exemplary embodiments of the invention are disclosed.
US09802037B2 Tension loop for a spinal cord stimulator
An electrical stimulation device comprises a stimulation lead with a tension section to prevent induction of an electrical current when the electrical stimulation device is in the presence of a magnetic field generated by a device such as an MRI machine. The tension section is shaped to organize excess length of the stimulation lead while providing a variable length between a distal end of the stimulation lead and an electrical source. The shape of the tension section avoids coils and may utilize combinations of straight and curved legs that lie substantially in a common plane to both organize excess length of the stimulation lead and prevent electrical induction.
US09802031B2 Creation of a polymer retention hub to form a conjunct nozzle
A novel design of a polymer retention hub created having an innovative feature used to permanently attach a thin wall nozzle core without use of adhesives or ancillary parts to form a conjunct nozzle. Additional polymer in the correct amount is molded into a polymer retention hub in close proximity to a location where a mechanical lock must be formed to join the two components together. The inventive design of the polymer retention hub is configured to produce an enclosed cavity with the strength required for separation of a nozzle core from a standard taper.
US09802029B2 Microneedle arrangement and adapter
Described is a microneedle arrangement (1) comprising a body (2) having a proximal portion and a distal portion, a plurality of recesses (7) formed in proximal portion of the body (2), a microneedle array (5) disposed on the distal portion, and a connection needle (8) in fluid communication with the microneedle array (5) and extending proximally from the microneedle array (5). Further described is an adapter (9) comprising a coupling adapted to engage a medicament delivery device, an opening (14) adapted to receive the body (2), and a plurality of resilient latches (12) adapted to releasably engage the plurality of recesses (7) of the microneedle arrangement (1) when the body (2) is inserted into the opening (14).
US09802018B2 Ergonomic and adjustable respiratory mask assembly with frame
A respiratory mask assembly for delivering breathable gas to a patient includes a frame having a front surface and a rear surface, opposite the front surface, and adapted in use to face the patient. The frame defines an inner wall and an outer wall extending from the rear surface, the inner and outer walls being spaced to define a channel therebetween. A cushion is removably attachable to the frame such that the cushion and frame are repeatably engagable with and disengagable from one another. The cushion includes a side wall to be inserted into the channel of the frame, the side wall having a first interlocking surface that engages a second interlocking surface provided in the channel when the cushion and frame are engaged with one another. The first and second interlocking surfaces interlock with one another to removably attach the cushion to the frame.
US09802017B2 Facial mask with custom-manufactured cushion element, and associated method
Disclosed is a method of forming at least a portion of a mask (4) that is structured to engage at least a portion of the face of a patient (52). The method can be generally stated as including employing at least a portion of a data set (74) that is stored on a machine-readable storage medium (72) and that is representative of the shape of at least a portion of the face in generating a configuration for an cushion element (24) of the mask. The cushion element is structured to extend from a support (20) of the mask and to have an engagement end (50) bopposite the support that corresponds with the shape of the at least portion of the face. The method can be generally stated as further including subjecting a workpiece (78) to a formation operation to cause at least a portion of the workpiece to be formed into the cushion element having the engagement end.
US09802015B2 CPAP systems
A CPAP system includes a flow generator (10), a patient interface (50), an air delivery conduit (20) that interconnects the flow generator and the patient interface, wherein the air delivery conduit has an internal diameter of less than 19 mm. Preferably the air delivery conduit has an internal diameter of between about 10 mm and about 18 mm. The CPAP system may also include a controller for compensating for pressure swings and/or increased impedance within the system. Preferably the blower includes a low inertia blower.
US09802014B2 Apparatus and method for improved assisted ventilation
Devices and methods for allowing for improved assisted ventilation of a patient by allowing blind insertion of a device that can allow ventilation regardless of whether the device is positioned within a trachea or an esophagus and allow for timed delivery of ventilations based on a condition of a thoracic cavity to increase the amount and efficiency of blood flow during a resuscitation procedure.
US09802011B2 Drug dose cartridge for an inhaler device
Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges including at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.
US09802006B2 Medical needle removal and storage method
An apparatus for removing a needle from a needle holder, including a grasping unit for selectively grasping the needle; a receiving unit for receiving the needle holder, displaceably disposed relative to the grasping unit; a biasing member biasing the receiving unit in a first direction; and separating means for separating the entire needle from the needle holder. Preferably, the needle is heated to melt, soften, or otherwise weaken a material and/or adhesive connecting the needle with the needle holder. Preferably the heating is electrical heating, including completing an electrical circuit through the needle and passing current through the needle, and/or passing current through a heating element.
US09802001B2 Dispensing speed control mechanism and injection device
The present invention relates to a dispensing speed control mechanism for use in an injection device. The injection device may have a housing (10, 30, 40; 40′; 40″; 40′″) and a drive member (70), which is driven by a power reservoir (100, 100′) and axially movable between a dose setting position, in which the drive member (70) is rotationally constrained to the housing (10, 30, 40; 40′; 40″; 40′″), and a dose dispensing position, in which the drive member (70) is rotationally de-coupled from the housing (10, 30, 40; 40′; 40″; 40′″). The speed control mechanism comprises friction means (42) for retarding the drive member (70) during dose dispensing depending on the axial position of the drive member (70). Further, the invention relates to an injection device with such a dispensing speed control mechanism.
US09802000B2 Extended finger flange for syringe systems
The present disclosure describes an extended finger flange that facilitate use of syringe systems. The extended finger flange increases the surface area available for an end user's fingers thereby allowing a more secure grip on the device and providing greater control during administrations of the medication.
US09801999B2 Manufacturing method of two-chamber type combined container-syringe
A manufacturing method of two-chamber type combined container-syringe including: a vacuum plugging process (S2) of eliminating air bubbles from the dissolving solution of the dissolving solution-filled cartridge and sealing the dissolving solution with a middle stopper after the dissolving solution filling process (S1); a vacuum plugging process (S2) has a first cooling processing (S21) of cooling the inside of a vacuum plugging equipment in which a dissolving solution-filled cartridge is disposed to a cooling temperature that does not freeze the dissolving solution, a first decompression processing (S23) of decreasing a pressure inside the vacuum plugging equipment while the vacuum plugging equipment maintains the cooling temperature after the first cooling processing (S21), and a middle stopper pushing processing (S24) of pushing the middle stopper downward and bringing the middle stopper into contact with the dissolving solution after the first decompression processing (S23). The dissolving solution can be easily filled in a bubble-free state in the two-chamber type combined container-syringe.
US09801997B2 Infusion pump systems and methods
Some embodiments of an infusion pump system can include a controller in which one or more features sets to be provided by the controller are enabled or disabled based upon the particular pump device that is connected to the controller. For example, in some embodiments, one or more advanced features of the controller are available to the user only when a first type of pump device (e.g., having predefined settings stored therein) is connected to the controller, and those advanced features of the controller are disabled when a second type of pump device is connected to the controller.
US09801993B2 Sensor clip assembly for an optical monitoring system
Systems and sensor clip assemblies for optically monitoring blood flowing through a blood chamber are provided. A sensor clip assembly includes emitters and photodetectors positioned on opposing arms, a signal conditioning circuit for conditioning raw analog signals generated by the photodetectors while the sensor clip assembly is fastened to a blood chamber, and an analog-to-digital converter for converting the conditioned analog signals to raw digital data. The sensor clip assembly may output the raw digital data to an external device and receive synchronized control signals from the external device, or the sensor clip assembly may include a microcontroller for performing calculations on the raw digital data and providing synchronized control signals internally. Parameters of blood flowing through the blood chamber such as hematocrit, oxygen saturation, and change in blood volume may be calculated from the raw digital data derived from the raw analog signals generated by the photodetectors.
US09801988B2 Generating artificial pulse
In order to produce a pulsatile blood flow pattern that includes time periods of relatively high blood flow rates and time periods of relatively low blood flow rates, the operating speed of a blood pump can be selectively controlled to produce an operating speed pattern that includes time periods of relatively high rotation speeds and periods of relatively low rotation speeds. For example, the blood pump is rotated at a first speed for a first period of time. The speed of the blood pump is then decreased from the first speed to a second speed and is operated at the second speed for a second amount of time. The speed of the blood pump is then decreased to a third speed for a third amount of time. If desired, the operating speed pattern can be repeated to continue the pulsatile blood flow pattern.
US09801987B2 Bifurcated outflow cannulae
A bifurcated cannula for directing blood into the arterial system. The bifurcated cannula including an ingress channel and first and second egress channels. The first egress channel directs a first portion of the blood entering the bifurcated cannula into the arterial system in a first direction. The second egress channel directs a second portion of the blood entering the bifurcated cannula into the arterial system in a direction that opposes the first direction.
US09801983B2 Medical devices for delivering a bioactive to a point of treatment and methods of making medical devices
Methods of making medical devices are described. A method of making a medical device for delivering a bioactive includes preparing a suitable solution comprising the bioactive; placing a vessel containing the solution over a substrate comprising a biocompatible foam and defining open cells; initiating flow of the solution from the vessel and toward the substrate such that the solution exits the vessel and contacts the substrate; and maintaining flow of the solution for an amount of time sufficient to achieve a desired volume of the solution within the substrate. Medical devices made by the methods are also described.
US09801982B2 Implantable barrier device
A barrier device is formed of a barrier component that can exhibit anti-inflammatory properties, non-inflammatory properties, and/or adhesion-limiting properties, as well as generate a modulated healing effect on injured tissue. The barrier component can be a non-polymeric cross-linked gel derived at least in part from a fatty acid compound, and may include a therapeutic agent. The barrier device can have anchoring locations to provide an area on the barrier device to interface with an anchoring mechanism. The anchoring locations can include openings and/or anchor elements. The barrier device can also include truss structures that provide additional strength to the barrier component. The barrier device is implantable in a patient for short term or long term applications, and can include controlled release of the therapeutic agent.
US09801981B2 Medical device balloons with improved strength properties and processes for producing the same
A tubular parison for forming a medical device balloon. The parison is formed of a polymeric material, for instance a thermoplastic elastomer. The parison has an elongation at break which is not more than 80% of the elongation of the bulk polymeric material. The elongation of the parison is controlled by altering extrusion conditions. Balloons prepared from the parisons provide higher wall strength and/or higher inflation durability than balloons prepared from conventional parisons of the same material.
US09801979B2 Catheter assembly with osmolality-increasing fluid
A catheter assembly includes a hydrophilic catheter; a wetting fluid for wetting of the catheter; and a receptacle enclosing at least the insertable part of the catheter and the wetting fluid. The wetting fluid is a solution incorporating at least one osmolality-increasing compound, and the total concentration of the osmolality-increasing compound(s) preferably exceeds 600 mOsm/dm3. The wetting fluid could either be arranged in contact with the hydrophilic surface layer of the catheter in the receptacle, for preservation of the hydrophilic surface layer in a wetted state during accommodation in said receptacle and provision of a ready-to-use catheter assembly, or be arranged to keep the wetting fluid separated from the hydrophilic surface layer of the catheter during storage, but to be brought into contact with said hydrophilic surface layer upon activation before an intended use of the catheter.
US09801971B2 Transdermal therapeutic patches containing 4-N-butylresorcinol
Transdermal therapeutic systems that contain 4-n-butylresorcinol as an active ingredient.
US09801970B2 Decorative fragrance dispensing system
A fragrance dispensing apparatus includes a housing. The housing includes a platform configured to receive an ethylene vinyl acetate (EVA) bead packet. The EVA bead packet remains substantially unheated by the fragrance dispensing apparatus during operation of the fragrance dispensing apparatus. The fragrance dispensing apparatus further includes a lower module. The lower module includes a fan configured to selectively actuate airflow through the EVA bead packet.
US09801969B2 Scented attachment for containers
Aspects of the disclosure include an attachment for providing a scent to a container. In some aspects, a scent delivery system includes a bottle including a collar and a ledge structure each extending circumferentially outward; a scent ring loaded with a volatile chemical agent to emanate and generate a scent and including an interior protruding structure projecting from an interior wall of the ring, the scent ring configured to fasten around the neck of the bottle based on contact between the interior protruding structure and the ledge structure of the bottle; and a cap reversibly attachable to the bottle and including an interior rim structure that circumferentially projects from the interior of the cap, where the cap is structured to enclose the scent ring in a compartment formed between the collar and the interior rim structure when the cap is securely fastened to the bottle and trap the scent.
US09801968B2 Lighted air freshener assembly
A lighted air freshener assembly provides a fragranced odor and illumination as well as the ability to be hung from a support structure, such as a Christmas tree. The assembly includes a support base having a top wall, a bottom wall and a perimeter wall coupled to and extending between the top wall and the bottom wall. At least one light emitter is coupled to the support base. A scent device is coupled to the support base and includes a scented material for emitting a fragranced odor. A decorative casing is positionable over the scent device and is removably couplable to the support base.
US09801964B2 Evaporative cycles of concentration control
A cycles of concentration (COC) control process and system for an evaporative media cooling system having a water storage tank in fluid communication with a drain valve and a refill valve is disclosed. In one step, the COC control process includes the step of executing a plurality of discrete refill events to maintain a level or volume of water within the storage tank. In another step, the COC control process includes the step of executing a discrete drain event, equaling the volume of a refill event, after a discrete refill event has been executed when necessary to maintain a target cycles of concentration value of the water within the storage tank. In one embodiment, a discrete drain event is executed when the number of refill events is greater than or equals a target cycles of concentration of the water in the storage tank.
US09801962B2 Radioactive nanoparticles and methods of making and using the same
In one aspect, radioactive nanoparticles are described herein. In some embodiments, a radioactive nanoparticle described herein comprises a metal nanoparticle core, an outer metal shell disposed over the metal nanoparticle core, and a metallic radioisotope disposed within the metal nanoparticle core or within the outer metal shell. In some cases, the radioactive nanoparticle has a size of about 30-500 nm in three dimensions. In addition, in some embodiments, the radioactive nanoparticle further comprises an inner metal shell disposed between the metal nanoparticle core and the outer metal shell. The metal nanoparticle core, outer metal shell, and inner metal shell of the radioactive nanoparticle can have various metallic compositions.
US09801960B2 Probe for a biological specimen and labelling method and screening method using the probe
Provided is a novel probe for a biological specimen for labelling by itself and clearly visualizing one of a specific cell and a specific cell organ in a living body, the probe having excellent spectral characteristics and exhibiting excellent storage stability. The probe for a biological specimen contains, as an active agent, at least one kind of compound represented by a general formula (I).
US09801959B2 Phospholipid composition and microbubbles and emulsions formed using same
A composition for stabilizing a fluorocarbon emulsion. That composition includes phosphatidylcholine, phosphatidylethanolamine-PEG, and a cone-shaped lipid.
US09801958B2 Polymer nanoparticle composite and composition for MRI imaging including same
The present invention provides a safe polymer nanoparticle composite with few side effects, and an MRI contrast agent incorporating said polymer nanoparticle composite. The polymer nanoparticle composite is capable of specifically accumulating on a tumor tissue to selectively extract the tissue, exhibiting high contrast even when used in small amounts, and enabling imaging over prolonged periods of time. This polymer nanoparticle composite is characterized by containing a block copolymer that includes a non-charged hydrophilic polymer chain segment and an anionic polymer chain segment, and MnCaP.
US09801956B2 PSMA-targeted NIR dyes and their uses
The present disclosure relates to prostate specific membrane antigen (PSMA) targeted compounds conjugated to near-infra red (NIR) dyes and methods for their therapeutic and diagnostic use. More specifically, this disclosure provides compounds and methods for diagnosing and treating diseases associated with cells and/or vasculature expressing prostate specific membrane antigen (PSMA), such as prostate cancer and related diseases. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
US09801947B2 Methods and compositions for enhancing immune response
Methods and compositions for enhancing the immune response to an IRM compound by depositing within a localized tissue region an IRM depot preparation that provides an extended residence time of active IRM within the localized tissue region.
US09801946B2 Synthetic polyurethane composite
Embodiments of the present inventions comprise composites of polyurethane(s), osteoconductive matrix, and, optionally, a growth factor. Embodiments further comprise methods of making such composite and uses thereof. The osteoconductive matrix can be a tricalcium phosphate, bioglass, or the like, and can include particles that are surface modified. Growth factors can be provided in powder form, including bone morphogenic proteins such as rhBMP-2. A composition may be moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells.
US09801940B2 Oral care compositions
Disclosed herein are methods of enhancing the solubility and delivery of one or more active ingredients found in magnolia extract, or a synthetic analog thereof, in an oral composition.
US09801937B1 Method for targeting antigens unique to a tumor
A method and system for targeting antigens unique to a tumor site. The method can include a first phase of monoclonal antibodies that bind to the tumor site. A second phase of monoclonal antibodies can be administered that bind to the first phase. A third phase of monoclonal antibodies can be administered that bind to the second phase. The third phase can include radionuclides to allow the tumor site to be imaged. Once identified, a phase of toxins can be administered, resulting in death of the tumor cells.
US09801921B2 Use of pertussis toxin as a therapeutic agent
The present application relates to the use of a pertussis toxin, and its derivatives, analogs, salts and pharmaceutical equivalents. In one embodiment, the invention provides a method of treating an autoimmune disease by administering pertussis toxin to the individual. In another embodiment, the autoimmune disease is multiple sclerosis. In another embodiment, the invention provides a method of treating a neurodegenerative disease such as Alzheimer's disease or Parkinson's disease by administering pertussis toxin, or a derivative, analog, salt or pharmaceutical equivalent.
US09801920B2 Antimicrobial composition comprising Filobasidium-suppressing agent derived from natural substance
The present invention relates to an antimicrobial composition derived from a natural substance. Since the composition effectively suppresses Filobasidium, an organism that has been newly identified as causing dandruff, the present invention can effectively prevent and/or treat seborrhoeic dermatitis and dandruff. Also, since the antimicrobial composition of the present invention includes a natural substance as an active ingredient, little consumer aversion will result. Also, it is expected that the antimicrobial composition of the present invention can be used for developing an antidandruff agent having a reduced content of materials which are typically used as antidandruff agents and the safety of which is questionable.
US09801919B2 Oral compositions containing enhanced antibacterial combinations of antioxidants and extracts of magnolia
An oral composition contains an enhanced antibacterial effective amount of an antioxidant and an extract of Magnolia.
US09801916B2 Oral antiseptic composition useful for treating oral mucositis
Antiseptic pharmaceutical composition useful for the treatment of painful lesions in oral mucosa, ulcerative and inflammatory lesions of different origin and the treatment and/or prevention of oral mucositis and stomatitis.
US09801915B2 Probiotic and polyphenol against neurodegeneration
The present invention relates to a composition comprising the probiotic strain Lactobacillus johnsonii CNCM I-1225 in combination with a polyphenol for use in the treatment or prevention of a cognitive and/or neurodegenerative disorder, in particular Alzheimer's disease.
US09801909B2 Compositions and methods for combating bacterial infections by killing persister cells with mitomycin C
The present disclosure provides a method for killing persister cells with mitomycin C and/or cisplatin, or derivatives thereof. Recalcitrant infections are difficult to treat due to persister cells, a subpopulation of all bacterial populations that is highly tolerant against all traditional antibiotics since the cells are dormant and antibiotics are designed to kill growing cells. Here, we show that MMC and cisplatin eradicate persister cells through a growth-independent mechanism, cross-linking DNA. We find both agents are effective against both planktonic cultures and highly robust biofilm cultures for a broad range of bacterial species, including commensal Escherichia coli K-12 as well as pathogenic species of E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In certain approaches cisplatin is superior to MMC.
US09801908B2 Treatment for chitin-containing microorganisms
The present disclosure relates to treatment of chitin-containing microorganism infection or colonization on an aquatic animal. The methods, systems, and kits provided herein facilitate termination and/or inhibition of proliferation of chitin-containing microorganisms (e.g., Saprolegnia and sea lice).
US09801905B2 Use of organic sulphur, antioxidants, and amino acids in conjunction with exercise and electromagnetic stimulation to treat osteoporosis
Through the use of a combination of naturally occurring substances, application of mechanical energy by way of exercise, and application of a pulsed electromagnetic field (PEMF), new bone formation at lines of stress can be promoted. This bone forming activity is useful in the treatment and prevention of osteoporosis. The naturally occurring substances consist of organic sulphur, antioxidants, and amino acids. These substances are preferably administered orally. In preferred embodiments, the antioxidant is alpha-lipoic acid, and the amino acid is selected from the group consisting of lysine, glutamine, and mixtures thereof.
US09801904B2 Selenium-containing compositions and uses thereof
The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
US09801897B2 Delivery of RNA to trigger multiple immune pathways
RNA encoding an immunogen is co-delivered to non-immune cells at the site of delivery and also to immune cells which infiltrate the site of delivery. The responses of these two cell types to the same delivered RNA lead to two different effects, which interact to produce a strong immune response against the immunogen. The non-immune cells translate the RNA and express the immunogen. Infiltrating immune cells respond to the RNA by expressing type I interferons and pro-inflammatory cytokines which produce a local adjuvant effect which acts on the immunogen-expressing non-immune cells to upregulate major histocompatibility complex expression, thereby increasing presentation of the translated protein to T cells. The effects on the immune and non-immune cells can be achieved by a single delivery of a single RNA e.g. by a single injection.
US09801895B1 Cream formulation with amphotericin B and oil in water useful for topical application to mucous tissue and skin against diseases produced by leishmaniasis
The cream formulation of the present invention is a topical cream made with antimycotic (amphotericin B) and a mixture of excipients where the water present in the formulation smoothes inflamed tissue. The cream has a particular application for the treatment of cutaneous leishmaniasis and mucosal leishmaniasis in humans and animals. The topical application avoids the risks of toxicity and the gastrointestinal hassles of pills treatments. It has greater acceptability from patient and does not require of valuations before, during or after treatment to check toxicity levels of the liver, kidney and heart.
US09801889B2 Bicyclic heterocycles as FGFR4 inhibitors
The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR4 enzyme and are useful in the treatment of FGFR4-associated diseases such as cancer.
US09801887B2 Method of treatment of aggression
The invention comprises a method of treatment of aggression and similar behavioral syndromes, such as impulsivity and irritability, by a pharmaceutical agent exhibiting combined D2 and D5 antagonistic activity.
US09801882B2 Phosphodiesterase-1 inhibitors and their use in treatment of cardiovascular diseases
The invention relates to the administration of inhibitors of phosphodiesterase 1 (PDE1) for the treatment of diseases or disorders characterized by disruption of or damage to various cGMP/PKG mediated pathways. In one embodiment the invention relates to inhibitors of phosphodiesterase 1 (PDE1) for treatment of cardiovascular disease and related disorders, e.g., congestive heart disease, atherosclerosis, myocardial infarction, and stroke.
US09801875B2 Compositions and methods for weight loss in at risk patient populations
The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject at increased risk of adverse cardiovascular outcomes. Preferably, the subject has had type-two diabetes for a period of less than 6 years or is a current smoker, optionally that does not have type-two diabetes.
US09801874B2 Method for the preparation of liposome encapsulated vincristine for therapeutic use
Improved methods for efficiently constituting liposome encapsulated vincristine for intravenous injection (VSLI) with reduced risk of operational errors and contamination are disclosed.
US09801872B2 Pyridinyl and fused pyridinyl triazolone derivatives
Disclosed are compounds of Formula 1, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.
US09801871B2 6-alkynyl-pyridine derivatives
6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. An exemplary compound is
US09801868B2 5-substituted isoindoline compounds
This invention relates to 5-substituted isoindoline compounds, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.
US09801867B2 Processes of making and crystalline forms of a MDM2 inhibitor
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.
US09801862B2 Immunosuppressive treatments, formulations and methods
The present disclosure provides inventive methods and formulations for immunosuppressive therapy for dry eye and other related immune mediated eye diseases. The formulations can comprise one or more immunomodulatory drugs such as parenterally administered liposome encapsulated rapamycin and topically administered tacrolimus. Immunomodulatory drugs herein can be formulated and administered to address the causes and/or reduce the symptoms of dry eye and/or other related immune mediated diseases of the eye.
US09801858B2 Progress-supressing or improving agent for chronic kidney disease
An object of the present invention is to provide a pharmaceutical agent which is administered to a patient with chronic kidney disease in which the progress of worsening of renal function is rapid whereby the progress of the symptom is suppressed or improved.The present invention relates to a progress-suppressing or improving agent for chronic kidney disease containing 5-hydroxy-1-methylhydantoin as an active ingredient. The pharmaceutical agent of the present invention showed a significant effect in a patient with chronic kidney disease where progress of the renal function decrease is rapid. The present pharmaceutical agent is very useful as a highly safe pharmaceutical agent which suppresses or improves the progress of worsening of the renal function of a patient with rapidly progressive chronic kidney disease for which there has been no effective therapeutic agent being simply and easily ingestible.
US09801855B2 Nanocrystalline solid dispersion compositions and process of preparation thereof
The present invention relates to a method of preparation of discrete particles of nanocrystalline solid dispersion, wherein said discrete particle comprises crystals of said active ingredient(s) in the matrix of the said crystallization inducer(s) and/or coexisting with crystals of crystallization inducer(s), optionally along with pharmaceutically acceptable excipient(s). An active ingredient and crystallization inducer is dissolved in a solvent or solvent mixture and then dried to obtain discrete particles of 0.5 to 20 micron size. Each particle consists of crystals of active ingredient in the range of 10-1000 nm dispersed in the matrix of crystallization inducer.
US09801854B1 Slow release formulations of cell cycle regulators and anti-cancer agents for local treatment of solid cancer
Provided herein are methods for treating cancer of a body cavity, including specifically urinary tract cancer, by way of at least one cell cycle regulator, and at least one anti-cancer drug for local treatment; wherein the therapeutic agents are embedded in, and slowly released from, a biocompatible hydrogel composition.
US09801846B2 Composition comprising EPA and DHA ethylester for parenteral administration
Described herein are compositions for parenteral administration that include an aqueous phase and 5 to 30%, by weight, of an oil phase, based on the total weight of the composition. The oil phase comprises the omega-3 fatty acid ethylesters eicosapentaenoic acid ethylester, docosahexaenoic acid ethylester, and mixtures thereof. The composition further comprises at least one anionic surfactant and at least one amphoteric surfactant, and less than 0.05% by weight of oleic acid, based on the total weight of the composition. Also described is a method for preparing such a composition as well as such compositions for use as a medicament, in particular for use in treating stroke, sepsis, Alzheimer's disease or cancer. Also featured are methods of treating these conditions by parenterally administering a composition to a patient in need thereof and methods of providing parenteral nutrition to such patients by administering to them a composition as described herein.
US09801845B2 Antimicrobial compositions and uses thereof
Antimicrobial compositions comprising sulfur- or selenium-containing, fatty-acylated alpha-hydroxy acid compounds and methods of using said compounds or compositions to inhibit microbial growth.
US09801843B2 Self-emulsifying composition of ω3 fatty acid
A self-emulsifying composition contains: 70 to 90% by weight in total of one or more compounds selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters; 1 to 29% by weight of an emulsifying agent selected from among a polyoxyethylene sorbitan fatty acid ester, a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyl castor oil; and 0.5 to 6% by weight of water when the composition is defined to be 100% by weight as a whole. The self-emulsifying composition is excellent in self-emulsifying property, composition dispersibility, emulsion stability, and absorbability, is free from ethanol and polyhydric alcohols or only has such an alcohol added thereto at a reduced concentration, and is useful for foods and pharmaceuticals.
US09801834B2 Controlled release delivery system for nasal application of neurotransmitters
This invention relates to a galenical gel formulation for nasal administration of neurotransmitters/neuromodulators such as dopamine, serotonin or pregnenolone and progesterone. The special lipophilic or partly lipophilic system of the invention leads to high bioavailability of the active ingredient in plasma and brain caused by sustained serum levels and/or direct or partly direct transport from nose to the brain.
US09801833B2 Compositions and methods using tiglic aldehyde
Compositions contain a therapeutically effective amount of tiglic aldehyde for at least one of provoking the swallowing reflex of dysphagic patients, decreasing appetite by delaying gastric emptying, reducing body weight gain, or reducing glycemia by improving insulin sensitivity improving mood, memory or cognition. Methods are provided that include administering such compositions.
US09801832B2 Pharmaceutical composition having synergistic action of direct catalase inhibitors and modulators of no metabolism or of extracellular superoxide anion production which lead to catalase destruction
The present patent application relates to a pharmaceutical composition, characterized in that it comprises at least one active ingredient which can bring about a singlet oxygen-independent direct catalase inactivation and that the composition further comprises at least one active ingredient that leads to inactivation of catalase as a result of modulation of the nitrogen oxide or superoxide anion metabolism of the cells and subsequent singlet oxygen formation.
US09801826B2 Accordion pill comprising levodopa for an improved treatment of Parkinson's Disease symptoms
The invention provides for the use of an accordion pill comprising levodopa for the treatment of symptoms of Parkinson's disease in a subject in need thereof over a 24 hour period, to be administered to the subject in a twice daily administration regimen, with an interval of about 8 to about 10 hours between the first dose and the second dose, and with an interval of about 14 to about 16 hours between the second dose and the first dose of the following day. The twice daily administration regimen provides a stable blood plasma level of levodopa in the subject after multiple administrations and is effective in treating the symptoms of Parkinson's disease over a 24 hour period.
US09801819B2 Racecadotril compositions
A lipid composition comprising racecadotril, at least one surfactant and a lipid.
US09801818B2 Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug
A method for stabilizing a poorly water-soluble drug-containing amphiphilic block copolymer micelle composition via simplified steps in short time is described. Also described is a stabilized poorly water-soluble drug-containing amphiphilic block copolymer micelle composition having improved stability.
US09801816B2 Gastric retentive dosage forms for extended release of acamprosate into the upper gastrointestinal tract
Gastric retentive dosage forms for sustained release of acamprosate are described which may allow once- or twice-daily dosing for both acute and long-term treatment of a disorder including alcohol dependence, tinnitus, sleep apnea, Parkinson's disease, levodopa-induced dyskinesias in Parkinson's disease, Alzheimer's disease, Huntington's disease, Amyotrophic lateral sclerosis, Cortical spreading depression, migraine, schizophrenia, anxiety, tardive dyskinesia, spasticity, multiple sclerosis, various types pain, or binge eating. Methods of treatment using the dosage forms and methods of making the dosage forms are also described.
US09801815B2 Galenical form for the administration of triptans by buccal transmucous means
A galenical form for the buccal transmucous administration of at least one active ingredient of the triptan family, includes at least: the active ingredient in basic form and in salt form, and a hydro-alcoholic solution that titrates at least 15 degrees of alcohol, whereby the active ingredient is present in a stable and complete state of dissolution in the hydro-alcoholic solution so as to allow a fast absorption of the active ingredient through the mucous membranes of the buccal cavity and/or the oropharynx. A process for the production of this galenical formulation as well as its use are described.
US09801813B2 Preservative-free ophthalmic pharmaceutical formulation
The present invention relates to a process for manufacturing an ophthalmic formulation of a carbonic anhydrase inhibitor, hydroxyl ethyl cellulose (HEC), and a beta-adrenergic antagonist for use in the treatment of ocular hypertension and glaucoma wherein the ophthalmic pharmaceutical formulation is devoid of benzalkonium chloride or any other preservatives. The present process for manufacturing is simpler, cost effective process to prepare the pharmaceutical ophthalmic formulation in a single tank, without the use of additional tanks that can be sterile filtered.
US09801812B1 Injectable non-aqueous compositions and methods of treating vascular disease
An injectable non-aqueous composition and a method of treating a vascular disease, the non-aqueous composition including: chitosan having a particle size of no greater than 50 μm; alginate having a particle size of no greater than 50 μm; and a non-aqueous carrier; wherein upon combination and injection into the vascular system of a subject, the composition causes a diseased portion of the vascular system to be absorbed into surrounding tissue.
US09801807B2 Topical formulations for increasing the dermal concentration of hyaluronic acid
Described herein are methods and compositions for increasing dermal concentrations of glycosaminoglycans (GAG), including hyaluronic acid. Exemplary methods involve a one-step protocol and a three-step protocol. Either method can be used over a 90-day treatment period.
US09801805B2 Personal care composition comprising silicone network
The invention is directed to a personal care composition which contains a crosslinked ionic silicone network wherein the crosslinked ionic silicone network is formed by the ring-opening polymerization of oxirane moiety.
US09801804B2 Compositions and methods for treating hair
Disclosed are hair styling compositions comprising at least two latex polyurethane polymers, wherein at least one latex polyurethane polymer is a film-forming polymer, and at least one component chosen from thickening agents. Methods of styling the hair are also disclosed.
US09801801B2 Glyoxal-free cellulose derivatives for personal care compositions
The present application describes personal care compositions, comprising a surfactant and agglomerated cellulose derivative, provided that the cellulose derivative has been agglomerated with a sufficient amount of carboxymethylcellulose as binder, and provided that the personal care composition is substantially free of glyoxal.
US09801799B2 Compositions and methods for the removal of tattoos
The present invention provides a method for removing a tattoo in a region of skin the method comprises administering to a least a portion of the tattoo a composition comprising an effective amount of a bisphosphonate and at least one pharmaceutically acceptable excipient to at least cause fading of the tattoo in said region.
US09801798B2 Moisturizing composition
The present invention relates to a composition, in particular a cosmetic composition, comprising, in a physiologically acceptable medium, at least glyceryl caprylate, 1,3-propanediol and phytic acid or any of the salts thereof, said composition being free from perlite.The present invention further relates to a composition, in particular a cosmetic composition, comprising, in a physiologically acceptable medium, at least glyceryl caprylate, 1,3-propanediol and phytic acid or any of the salts thereof.
US09801791B2 Medication dispensing cart
A medication dispensing cart having a computer and monitor, a work surface with pull out keyboard, and plural drawers arranged as a vertical series of cassettes that can be added as needed. The battery powered device uses software and pass codes for controlling access to each drawer, and requires a second pass code for any drawer designated to contain narcotics. Records can be kept of who dispenses what medication and when for each cart in a system of carts. The cart in the system is in wireless communication with a system administrator. Emails alerting the system administrator of low battery power, of a cart switching to off, of an attempted break-in, and of inventory and usage data are sent automatically by email.
US09801786B2 Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
A drug container closure for mounting on an open-topped drug container to form a ready-to-use drug reconstitution assemblage for use with a needleless syringe. The drug container closure includes a drug container stopper for sealing the drug container and a fluid transfer member with an integral needleless syringe connector and a puncturing cannula. The fluid transfer member is manually disposed along a diametric inverted L-shaped track pair from an initial non-puncturing position to a puncturing position. The inverted L-shaped track pair includes one-way snap members to prevent a user returning the fluid transfer member to an earlier position and indicating progress of the user activation.
US09801781B2 Exercise device
A exercise roller device including a center roller portion provided with shaped end roller portions, and the center roller portion provided with a centered circumferential groove. A method of making the exercise roller device.
US09801777B2 Walking aid device
A walking aid device includes a support body inclusive of a plurality of support elements extending toward the ground. Each support element is coupled to a caster and a brake unit. Each brake unit has a clutching surface. The clutching surface controllably clutches a wheel of the caster or the ground to thereby generate friction for stopping the walking aid device.