Document | Document Title |
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US09605024B2 |
PAR4 agonist peptides
Protease activated receptor 4 (PAR4) agonist peptides are disclosed. These peptides are useful for developing robust PAR4 receptor assays. |
US09605023B2 |
Application of SP peptide or derivative thereof in preparing medicines for preventing or treating asthma
The present invention provides an application of an SP peptide or a derivative thereof in preparing medicines for preventing or treating asthma. The peptide or the derivative thereof is the SP peptide shown in Formula I or a pharmaceutically acceptable salt or ester thereof. The present invention also provides a method for treating asthma, the method comprises: administering to a patient with medicine containing the peptide or the derivative thereof with an effective therapeutic dosage. It proves through researches of the present invention that, the peptide or the derivative thereof can effectively alleviate pathological symptoms of asthma, especially pathological symptoms of allergic asthma. In the formula (I), Xaa1 is deletion, Ala, Gly, Val, Leu or Ile; Xaa2 is Thr or Ser; Xaa3 is Tyr, Phe or Trp; and Xaa4 is deletion, Ala, Gly, Val, Leu, Ile or Pro. Xaa1-Gln-Xaa2-Xaa3-Thr-Ser-Gly-Xaa4 (Formula I) |
US09605016B2 |
Method of esterification of carboxyl groups present on multihydroxyl cyclic polyene molecular structures carrying basic nitrogen groups
Disclosed is a process for the preparation of partricin alkyl esters which involves reacting partricin in a solvent with primary alkyl alcohols in the quantity of 5 to 1000 moles per mole of partricin in the presence of carbodiimides, and optionally in the presence of acylation catalysts and/or nitrogen bases or anhydrous acids. |
US09605015B2 |
Polyene compound, method for preparing the same, and antifungal drug comprising novel polyene compound as active ingredient
The present invention relates to a novel polyene compound similar to nystatin, a method for preparing the same, and an antifungal drug comprising the novel polyene compound as an active ingredient. Compared to nystatin comprising one sugar, NNP, which is the polyene compound similar to nystatin, displays 300 times higher solubility and ten times lower cytotoxicity while maintaining antifungal activity, and thus can be useful in developing a novel polyene antifungal agent having improved solubility and less toxicity in terms of pharmacokinetics. |
US09605013B2 |
Derivatives of hemin with antibacterial and antiviral activity
The invention relates to hemin derivatives of general formula (I), preparing and use thereof as antibacterial and/or antiviral agents, including, as a component in a pharmaceutical compositions. Advantages of the antibacterial and antiviral agents based on the hemin derivatives are in their biocompatibility, biodegradability, a high efficacy against resistant bacteria and widespread viruses which are dangerous to humans, and the lack of toxicity. |
US09605012B2 |
Palladium-ruthenium-zinc-organo complexes and methods for their use in the treatment of inflammatory diseases
The described invention provides organometallic complexes capable of spin transfer, comprising at least three different metals and the use of pharmaceutical compositions comprising such complexes in detoxification of reactive oxygen species in inflammatory conditions. |
US09605011B2 |
Monophosphite compounds having an ether group
Novel monophosphite compounds having an ether group, and a process for preparing these compounds, which are especially suitable for use as ligands in hydroformylation reactions. |
US09605009B2 |
Method for the purification of lecithin
A method for the purification of lecithin, comprising the steps of: a. reducing the viscosity of lecithin to a viscosity of less than about 10 Pa·s; then b. mixing the lecithin with granulated active carbon; then c. separating the lecithin from the granulated active carbon and recover purified lecithin. Lecithin substantially free of poly-aromatic hydrocarbons, and a food or feed product comprising said lecithin. |
US09605008B2 |
Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof
The present application relates to novel benzyl-1H-pyrazolo[3,4-b]pyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders. |
US09605005B2 |
Alkynyl alcohols and methods of use
The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed. |
US09605003B2 |
Heterocyclic compounds and uses thereof
Substituted bicyclic heterocyclic compounds such as isoquinolinone compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. |
US09604998B2 |
Inhibitors of the renal outer medullary potassium channel
The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure, kidney disease, edema, and conditions associated with excessive salt and water retention. |
US09604996B2 |
Cyclic thienouracil-carboxamides and use thereof
The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders. |
US09604995B2 |
Process for the preparation of olanzapine pamoate
An improved process for preparation of Olanzapine pamoate monohydrate from Olanzpaine is disclosed which comprises mixing at room temperature a solution of olanzapine prepared in water in presence of an acid, with a solution of pamoic acid prepared in water in presence of a base; stirring and maintaining the reaction mixture for a sufficient time till precipitation of solid and drying the solid to obtain olazapine pamoate monohydrate. |
US09604991B2 |
Preparation method of ticagrelor and intermediates thereof
Disclosed in the present invention is a method for preparing Ticagrelor (I), comprising the following steps: a cyclization reaction of 5-amino-1,4-di-substituted-1,2,3-triazole (II) and dialkyl carbonate (HI), to obtain 9-substituted-2,6-dihydroxy-8-azapurine (IV); chlorination of intermediate (IV), to obtain 9-substituted-2,6-dichloro-8-azapurine (V); an amination reaction of intermediate (V) and trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine (VI) generates 9-substituted-6-amino-substituted-2-chloro-8-azapurine (VII); and a propanethiolation reaction of intermediate (VII) and propanethiol (VIII), to obtain Ticagrelor (I). The preparation method is simple in process, has a high chemical and chiral purity and provides a new preparation method for industrializing Ticagrelor. In addition, also provided in the present invention are intermediates of Ticagrelor and a preparation method thereof, wherein raw materials of the preparation method are easily available, the conditions thereof are mild, and the yield thereof is high. |
US09604989B2 |
Imidazopyridazines as Akt kinase inhibitors
The present invention relates to a method for the treatment of a cancer that is sensitive to Pi3K/Akt pathway inhibition by administering a therapeutically effective amount of a compound of formula (I) |
US09604987B2 |
Synthesis of autophagy inducing compound and the uses thereof
The present invention relates to a composition comprising compound of formula CB6 or CB8, the pharmaceutically-acceptable carrier, solvent, the salts thereof or a combination thereof which is used to treat autophagy-associated diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, etc. The present invention also relates to a method of treating these diseases by administering a therapeutically-effective amount of the compound to the subject in need of the treatment. The present invention further relates to the use of this compound in preparation of the composition to treat the diseases. |
US09604986B2 |
Polymorphs and process for preparation of (2S, 5R)-7-oxo-N-[(2S)-pyrrolidin-2-yl-methyloxy]-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide
A process for preparation of compound of Formula (I) is disclosed. The application is also directed to polymorphic forms of the compound of formula (I). |
US09604978B2 |
Compounds for inflammation and immune-related uses
The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders. |
US09604975B2 |
Indolyl-pyridone derivatives having checkpoint kinase 1 inhibitory activity
Compounds of formula (I) have checkpoint kinase 1 (CHK1) inhibitory activity: wherein R1, R2, R5 and R6 are independently selected from hydrogen, hydroxy, methyl, trifluoromethyl, hydroxymethyl, methoxy, trifluoromethoxy, methylamino and dimethylamino; R3, and R4 are independently selected from hydrogen, hydroxy, C1-C3 alkyl, fluoro-(C1-C3)-alkyl, hydroxy-(C1-C3)-alkyl, C1-C3 alkoxy, fluoro-(C1-C3)-alkoxy, hydroxy-(C1-C3)-alkoxy, —N(R11)—R12, -Alk-N(R11)—R12, —O-Alk-N(R11)—R12, —C(═O)OH, carboxy-(C1-C3)-alkyl, or —C(═O)—NH—R13; Alk is a straight or branched chain divalent C1-C6 alkylene radical; R7 and R8 are independently selected from hydrogen, hydroxy, or C1-C3 alkoxy; X is a straight chain divalent C1-C3 alkylene radical, optionally substituted on one or more carbons by R9 and/or R10; W is selected from —C(═O)—N(—R16)— or —N(—R17)—C(═O)—; Y is hydrogen, C1-C3 alkyl, C1-C3 alkoxy, or halo; and Q is selected from optionally substituted phenyl, optionally substituted cyclohexyl, or an optionally substituted 6-membered monocyclic heteroaryl ring. |
US09604972B2 |
Nitrogen-containing heteroaromatic ring compound
A nitrogen-containing heteroaromatic compound is represented by the following formula (A). wherein Y is an oxygen atom or a sulfur atom, M is a substituted or unsubstituted nitrogen-containing heteroaromatic group, and Ar2 is a substituted aromatic hydrocarbon group having 6 to 18 ring carbon atoms, a substituted or unsubstituted monocyclic heteroaromatic group having 5 or 6 ring atoms, a dibenzofuran ring group that may be substituted with a substituent (excluding a 3-carbazolyl group and an N-carbazolyl group), a dibenzothiophene ring group that may be substituted with a substituent (excluding a 3-carbazolyl group and an N-carbazolyl group), or a nitrogen-containing polycyclic group among nitrogen-containing polycyclic groups respectively represented by the following formulas (1) to (5). |
US09604968B2 |
Pure crystalline Form II of L-malic acid salt of sunitinib and processes for its preparation
The present invention relates to pure crystalline Form II of an L-malic acid salt of sunitinib and a process for its preparation. The invention further provides crystalline Form II of an L-malic acid salt of sunitinib having a purity of at least 97.0%. The invention also provides crystalline Form II of an L-malic acid salt of sunitinib substantially free of an anti-oxidant. The invention also provides crystalline Form II of L-malic acid salt of sunitinib which remains chemically pure on storage at 25° C.±2° C. and 40° C.±2° C. at a relative humidity of 60%±5% and 75%±5%, respectively, for at least 1 month. |
US09604967B2 |
Azetidinyloxyphenylpyrrolidine compounds
The invention provides certain azetidinyloxyphenylpyrrolidine compounds, particularly compounds of formula I wherein R is hydrogen or methyl, and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I to treat overactive bladder. |
US09604964B2 |
Dihydropyrazole GPR40 modulators
The present invention provides compounds of Formula (I): (Formula (I), or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments. |
US09604962B2 |
Fungicidal azocyclic amides
Disclosed are compounds of Formulae 1, 1A, 1B and 1C including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R4a1, R4a2, A, Aa, G, M, W, Z1, Z3, X, J, J1 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention. |
US09604960B2 |
Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
Novel aryl, heteroaryl, and non-aromatic heterocyle substituted tetrahydroisoquinolines are described in the present invention. These compounds are used in the treatment of various neurological and physiological disorders. Methods of making these compounds are also described in the present invention. |
US09604954B2 |
2,3-Fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals
Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza. |
US09604951B2 |
Process for making HMF from sugars with reduced byproduct formation, and improved stability HMF compositions
Disclosed is a process for making HMF or a derivative of HMF by dehydrating one or more hexose sugars in a reduced oxygen environment. In another, related aspect, a method for improving the stability and resistance to degradation of an HMF product involves adding one or more antioxidants to the HMF product. |
US09604949B2 |
Prostaglandin conjugates and derivatives for treating glaucoma and ocular hypertension
Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma and elevated intraocular pressure are disclosed. Such compositions comprise an effective amount of prostaglandin conjugates or derivatives of the present invention. |
US09604947B2 |
Substituted 5-imino-1,2,4-thiadiazoles that can be used to treat neurodegenerative diseases
The present invention is based on the use of a broad family of 5-imino-1,2,4-thiadiazoles as potential new drugs for the treatment of diseases in which PDE7 inhibition is important, specially inflammatory diseases, autoimmune and neurodegenerative disorders. On the other hand, compounds of the 5-imino-1,2,4-thiadiazole family are here described, as well as their synthetic procedures, and they may have great application as drug or drug candidates.Therefore, a first aspect of the present invention is related to a compound of formula (I): |
US09604942B2 |
Preparation of haloalkoxyarylhydrazines and intermediates therefrom
The invention in this document is related to the field of preparation of haloalkoxyarylhydrazines and certain intermediates derived therefrom, where said intermediates are useful in the preparation of certain pesticides disclosed in U.S. Pat. No. 8,178,658. |
US09604941B2 |
Preparation method of conjugated compound containing bis(phenylsulfonyl)benzene structure and an organic electroluminescent diode device using the conjugated compound
The invention provides a conjugated compound containing a bis(phenylsulfonyl)benzene structure, a preparation method and an application thereof, the compound includes a chemical structure with one of structural general formulas as follows: the invention obtains a conjugated compound containing a bis(phenylsulfonyl)benzene structure by selecting multiple kinds of conjugated aromatic units to react with halogen-substituted bis(phenylsulfonyl)benzene in the manner of Suzuki coupling reaction, Buchwald-Hartwig coupling reaction or copper-catalyzed halogenated aromatic amination reaction. The novel compound prepared by the invention has the characteristic of fluorescence as well as a certain electrical conductivity, and thus can be applied to fabricate a light-emitting layer or an electron transport layer of an organic electroluminescent diode. |
US09604938B2 |
Amino quinazolines as kinase inhibitors
Disclosed are compounds having the formula (Formula I)): wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same. |
US09604937B2 |
Pyrimidine-2,4-diamine derivatives for treatment of cancer
A compound of formula (I), or a pharmaceutically-acceptable salt thereof. The compound is useful in the treatment of cancer or other diseases that may benefit from inhibition of MTH1. |
US09604934B2 |
Urea hydantoin derivatives as formyl peptide modulators
The present invention relates to urea hydantoin compounds, processes for preparing them, pharmaceutical compositions containing them, and their use as pharmaceuticals as modulators of the FPR2 receptor, and to methods of treating inflammatory diseases or conditions in a subject in need thereof by administering the compound(s) or pharmaceutical composition to the subject. |
US09604930B2 |
Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof
Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5 mediated disorders are also described. |
US09604925B2 |
Class II HMG-CoA reductase inhibitors and methods of use
Disclosed are compositions and methods for treating bacterial infections. |
US09604924B2 |
Substituted biaryl sulfonamides and the use thereof
Provided herein are substituted biaryl sulfonamide compounds, pharmaceutical compositions comprising the compounds, methods of their preparation, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or amelioration of various disorders, including cancer and proliferative disorders. In one embodiment, the compounds provided herein modulate initiation of protein translation. In one embodiment, the compounds provided herein are used in combination with surgery, radiation therapy, immuno therapy and/or one or more additional anticancer drugs for the treatment, prevention, and/or amelioration of cancer and proliferative disorders. |
US09604923B2 |
Small molecule inhibitors of STAT3 with anti-tumor activity
The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S31-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. |
US09604922B2 |
Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
The present invention provides compounds and pharmaceutical compositions for treating neurological diseases such as multiple sclerosis. |
US09604921B2 |
Sulfonium salt, resist composition and resist pattern forming process
A sulfonium salt of formula (0-1) is provided wherein W is alkylene or arylene, R01 is a monovalent hydrocarbon group, m is 0, 1 or 2, k is an integer: 0≦k≦5+4m, R101, R102 and R103 are a monovalent hydrocarbon group, or at least two of R101, R102 and R103 may bond together to form a ring with the sulfur atom, and L is a single bond, ester, sulfonic acid ester, carbonate or carbamate bond. A resist composition comprising the sulfonium salt as PAG exhibits a very high resolution when processed by EB and EUV lithography. A pattern with minimal LER is obtainable. |
US09604918B2 |
Carboxylic acid ester/carbamate compound with polymerizable functional group and fluorine atom group, and manufacturing method therefor
Provided are a fluorine-containing monomer soluble in a hydrocarbon-based solvent as well as excellent in water and oil repellence, and a manufacturing method therefor. The fluorine-containing monomer is a carboxylic acid ester/carbamate compound having a polymerizable functional group and a fluorine atom group, and represented by the following general formula: CaF2a+1O—(CbF2bO)c—C2F4COO—Z—(CONHR)d. The method for manufacturing the carboxylic acid ester/carbamate compound is comprised of the steps of making an isocyanate compound having a polymerizable functional group react with an alcohol such as a polyalkylene glycol, a cycloalkane dimethanol, or a polyhydric alcohol to produce a hydroxycarbamate, and subsequently making the resulting hydroxycarbamate react with a perfluoropolyether carboxylic acid halide. |
US09604916B2 |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
This invention relates to the treatment of androgen receptor-positive breast cancer in a subject, for example a female subject. Accordingly, this invention provides methods of: a) treating a subject suffering from breast cancer; b) treating a subject suffering from metastatic breast cancer; c) treating a subject suffering from refractory breast cancer; d) treating a subject suffering from AR-positive breast cancer; e) treating a subject suffering from AR-positive refractory breast cancer; f) treating a subject suffering from AR-positive metastatic breast cancer; g) treating a subject suffering from AR-positive and ER-positive breast cancer; h) treating a subject suffering from triple negative breast cancer; i) treating a subject suffering from advanced breast cancer; j) treating a subject suffering from breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments; k) treating, preventing, suppressing or inhibiting metastasis in a subject suffering from breast cancer; l) prolonging survival of a subject with breast cancer, and/or m) prolonging the progression-free survival of a subject with breast cancer; comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound, comprising administering to the subject a therapeutically effective amount of a SARM compound of this invention. |
US09604913B2 |
Crystalline diacylhydrazine and the use thereof
The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N′-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N′-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject. |
US09604912B2 |
Compositions and methods for the treatment of hyperglycemia and metabolic syndrome
The compositions and compounds of Formula I, Formula II, Formula III which includes a salts of polyunsaturated fatty acids in a molecular conjugate form with an amino acid L-leucine or its polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These salts may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, delayed release or sustained release, transmucosal, syrup, topical, parenteral administration, injection, subdermal, oral solution, rectal administration, nanoparticle, buccal administration or transdermal administration. Such compositions may be used to treatment of hyperglycemia, metabolic syndrome, diabetes, pre-diabetes, lowering triglycerides or its associated complications. |
US09604911B2 |
Process for the synthesis of agomelatine
Process for the industrial synthesis of the compound of formula (I): |
US09604910B2 |
Composition of 5-nitrobenzoate derivatives as anti-metastatic agent that inhibits tumor cell-induced platelet aggregation
Disclosed are 5-nitrobenzoate derivatives of Formula I, and the preparation method therefor, wherein R is referred to hydrogen (H), unsubstituted, mono-substituted, di-substituted or tri-substituted benzoyl moiety. 5-Nitrobenzoare derivatives of Formula I do not affect the platelet aggregation, possesses the inhibitory activity related to the tumor cell-induced platelet aggregation (TCIPA), and further specifically inhibits podoplanin-induced platelet aggregation. Therefore, 5-nitrobenzoates of the invention are applicable in its therapeutic use as the novel therapeutic agent in preventing tumor metastasis. |
US09604909B2 |
L-ornithine phenyl acetate and methods of making thereof
Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate. |
US09604908B2 |
Diether based biodegradable cationic lipids for siRNA delivery
Disclosed herein are novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. The cationic lipids can demonstrate enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver. The present invention employs low molecular weight cationic lipids with one short lipid chain coupled with inclusion of hydrolysable functionality in the lipid chains to enhance the efficiency and tolerability of in vivo delivery of siRNA. |
US09604903B2 |
Metathesis process
A process of metathesizing a feedstock in the presence of a metathesis catalyst and at least one catalyst enhancer. The catalyst enhancer can be selected from a sacrificial catalyst or a non-catalyst enhancer. The process exhibits improved reaction times and/or the metathesis catalyst can be used at very low concentrations. |
US09604898B2 |
Ozonolysis operations for generation of reduced and/or oxidized product streams
The present invention relates to methods for safe and efficient use of hydrogen and oxygen in ozonolysis operations. The invention also relates to an ozonolysis process involving elements of both reductive and oxidative ozonolysis which are integrated in a continuous process. In one embodiment, the ozonolysis process of the present invention uses hydrogen and/or oxygen generated from water and electricity, which may be recycled to generate water and/or electricity. |
US09604897B2 |
Ionic liquid composition
The present disclosure provides a composition for preparing aryl carboxylic acid; said composition comprising: at least one ionic liquid, at least one catalyst, at least one non-oxidizable polar solvent, and at least one oxidizable multi-alkylated arylene compound with no two successive ring positions bearing alkyl group. The present disclosure also provides a process for preparing aryl carboxylic acid. |
US09604896B2 |
Halogen-free catalyst system and method for producing benzoic acid
Disclosed is a halide-free catalyst system and method for oxidizing toluene to form benzoic acid in benzoic acid solvent. The catalyst system contains Co, at least one of Zr and Hf, and an alkali metal basic salt. |
US09604895B2 |
Lactate production process
A process for producing lactic acid is provided. The process comprises (a) reacting a stream rich in saccharide with sodium hydroxide in the presence of water to produce a reaction mixture comprising sodium lactate; (b) reacting at least a portion of the sodium lactate with HCl to produce lactic acid and sodium chloride; (c) converting at least a portion of the sodium chloride to chlorine and sodium hydroxide; and (d) recycling at least a portion of the sodium hydroxide produced in step (c) to step (a). Also provided are processes for the production of alkyl lactate, oligomeric lactic acid, lactide, alkyl lactyllactate, poly-lactic acid, propylene glycol and acrylic acid. |
US09604889B2 |
Isobaric pressure exchanger in amine gas processing
A system includes an amine gas processing system that includes a contactor configured to remove an acid gas from an untreated natural gas using an amine in a lean amine stream, output a treated natural gas, and output a rich amine stream. The system also includes a regenerator configured to regenerate the amine in the rich amine stream, output the lean amine stream, and output the acid gas. The system also includes an isobaric pressure exchanger (IPX) configured to transfer the rich amine stream from the contactor to the regenerator and to transfer the lean amine stream from the regenerator to the contactor. |
US09604887B2 |
Betaine based organic fertilizer
An organic fertilization method is provided using betaine based organic fertilizer product and/or betaine and fish fertilizer by-product based fertilizer product. The betaine based organic fertilizer product and/or betaine and fish fertilizer by-product based fertilizer product is applied to agricultural vegetation in one of multiple forms and by one of multiple methods. |
US09604882B2 |
Spinel forming refractory compositions, their method of production and use thereof
A particulate composition for use in alumina-magnesia spinel forming dry vibratable mixtures may include, based on the total weight of the particulate composition, from 95 to 99.9 wt % of a mixture of particulate Al2O3 and particulate MgO, and from 0.1 to 5 wt % binding agent, wherein at least a portion of the particles of said mixture of particulate Al2O3 and particulate MgO is present in the particulate composition as a coating of particles on the surface of other particles. Methods of producing and using the particulate composition are also described. |
US09604873B2 |
Lithium disilicate glass-ceramic, method for production thereof and use thereof
The invention relates to glass-ceramics based on the lithium disilicate system which can be mechanically machined easily in an intermediate step of crystallization and, after complete crystallization, represent a very strong, highly-translucent and chemically-stable glass-ceramic. Likewise, the invention relates to a method for the production of these glass-ceramics. The glass-ceramics according to the invention are used as dental material. |
US09604871B2 |
Durable glass ceramic cover glass for electronic devices
The invention relates to glass articles suitable for use as electronic device housing/cover glass which comprise a glass ceramic material. Particularly, a cover glass comprising an ion-exchanged glass ceramic exhibiting the following attributes (1) optical transparency, as defined by greater than 90% transmission at 400-750 nm; (2) a fracture toughness of greater than 0.6 MPa·m1/2; (3) a 4-point bend strength of greater than 350 MPa; (4) a Vickers hardness of at least 450 kgf/mm2 and a Vickers median/radial crack initiation threshold of at least 5 kgf; (5) a Young's Modulus ranging between about 50 to 100 GPa; (6) a thermal conductivity of less than 2.0 W/m° C., and (7) and at least one of the following attributes: (i) a compressive surface layer having a depth of layer (DOL) greater and a compressive stress greater than 400 MPa, or, (ii) a central tension of more than 20 MPa. |
US09604866B2 |
Device for manufacturing columnar curved tempered glass
The present invention discloses a device for processing columnar curved tempered glass. The device mainly comprises a glass heating furnace, a glass bending mechanism and a glass tempering mechanism connected sequentially, wherein the arrangement of each supporting roller in the rollers supporting the high temperature flat glass is changed from planar arrangement in space into curved arrangement corresponding to the shape of the glass to be formed, so that the glass bending mechanism enables the glass to suffer bending deformation. Transferring rollers for outputting the formed curved glass in the axial direction of the supporting roller are arranged at the clearance of the rollers of the bending mechanism. In the present invention, bending shaping and tempering of the high temperature flat glass are completed by two stations to break the normal procedure that bending shaping tempering are carried out by one bending appliance intensively, thereby providing a novel technological approach for processing columnar curved tempered glass. |
US09604865B2 |
Base material for disk process for producing the same, and disk roll
A process for producing a base material for disks including forming a raw slurry material into a platy shape and drying the plate, the raw slurry material containing inorganic fibers which have a wet volume of about 300 mL/5 g or larger and which are amorphous or have a degree of crystallinity of about 50% or lower. |
US09604862B2 |
Oxidation method, nozzle and system for treating waste water
The present invention relates to a device, particularly a nozzle, for treating waste water, said nozzle having an outer tube and an inner tube. An intermediate space is formed between the outer tube and the inner tube and said intermediate space between the outer tube and the inner tube is divided into at least two chambers in the longitudinal direction of the tubes. The inner tube tapers in the longitudinal direction and then widens again and has at least one opening into each chamber at the constricted area. On the inner side of the inner tube and/or in the interior thereof, the device preferably has a catalyst. The present invention further relates to a method for oxidizing polluted waste water and a system for performing the method. |
US09604861B2 |
Systems, compositions and methods for providing safe and healthy water and water-based products
A method for providing a safe and healthy water and water-based product, comprising: testing pretreated reverse osmosis water to determine whether it meets a first set of pre-defined specifications; introducing a pre-defined nutrient composition into the water, wherein the predefined nutrient composition comprising one or more of mineral nutrients, trace elements and nutritional supplements; testing the water to determine whether it meets a second set of pre-defined specifications; and disinfecting the water along with its container by UV irradiation from a UV light source to obtain a water product. |
US09604860B2 |
Suspension processing device
Provided is a technique capable of reducing power consumption at driving time in relation to a suspension processing device using an ultrasonic wave. A suspension processing device 1A is provided with a suspension processing unit 3A configured of a flow channel unit 30 in which a suspension flows, and a drive control unit 2A that controls driving of the suspension processing unit 3A. The suspension processing unit 3A has a first oscillator 40a and a second oscillator 40b provided in the flow channel unit 30. The drive control unit 2A includes a signal amplifier 22. A first oscillator 40a and a second oscillator 40b are electrically connected to each other via the signal amplifier 22, and the ultrasonic wave is generated between the first oscillator 40a and the second oscillator 40b. |
US09604857B2 |
Water purifier
The present invention provides a water purifier, the water purification capability of which can be maintained over a long period of time. The water purifier 1 has: an attachment main body 10 that has an inflow passage P11, into which tap water flows from an inlet 11, and outflow passages P12 and P13 communicating with outlets 12 and 13; and a water purification main body 20 that has a first flow passage P21, a second flow passage P22, a third flow passage P23, a first filter material 25 between the first flow passage P21 and the second flow passage P22, and a second filter material 26 between the third flow passage P23 and the second flow passage P22 and is rotatably mounted onto the attachment main body 10. During a parallel filter material mode, the first flow passage P21 and the third flow passage P23 communicate with the inflow passage P11 and the second flow passage P22 communicates with the outflow passage P12. During a serial filter material mode, the third flow passage P23 or the first flow passage P21 communicates with the inflow passage P11 and the first flow passage P21 or the third flow passage P23 communicates with the outflow passage P13. |
US09604856B2 |
Integral filter compression seal
A filter cartridge for installation in a housing having a housing seat includes a filtration media compiled in a cylindrical pack having a radially outer face, a radially inner face defining a central cavity, a first axial end face, and a second axial end face. An end cap having an attachment portion is bonded and sealed to an axial end of the filtration media. A hub portion connects the attachment portion to a non-circular locking portion axially spaced from the attachment portion. The locking portion extends radially beyond the width of the hub portion and includes a sealing face having at least one annular sealing element for sealing against the housing seat. |
US09604849B2 |
Nucleophilic porous carbon materials for CO2 and H2S capture
In some embodiments, the present disclosure pertains to methods of capturing a gas from an environment by associating the environment (e.g., a pressurized environment) with a porous carbon material that comprises a plurality of pores and a plurality of nucleophilic moieties. In some embodiments, the associating results in sorption of gas components (e.g., CO2 or H2S) to the porous carbon materials. In some embodiments, the methods of the present disclosure also include a step of releasing captured gas components from porous carbon materials. In some embodiments, the releasing occurs without any heating steps by decreasing environmental pressure. In some embodiments, the methods of the present disclosure also include a step of disposing released gas components and reusing porous carbon materials. Additional embodiments of the present disclosure pertain to porous carbon materials that are used for gas capture. |
US09604843B2 |
MEMS devices and methods for forming same
Embodiments of the present disclosure include MEMS devices and methods for forming MEMS devices. An embodiment is a method for forming a microelectromechanical system (MEMS) device, the method including forming a MEMS wafer having a first cavity, the first cavity having a first pressure, and bonding a carrier wafer to a first side of the MEMS wafer, the bonding forming a second cavity, the second cavity having a second pressure, the second pressure being greater than the first pressure. The method further includes bonding a cap wafer to a second side of the MEMS wafer, the second side being opposite the first side, the bonding forming a third cavity, the third cavity having a third pressure, the third pressure being greater than the first pressure and less than the second pressure. |
US09604839B2 |
Micro-electro-mechanical system (MEMS) and related actuator bumps, methods of manufacture and design structures
Micro-Electro-Mechanical System (MEMS) structures, methods of manufacture and design structures are provided. The method of forming a MEMS structure includes forming fixed actuator electrodes and a contact point on a substrate. The method further includes forming a MEMS beam over the fixed actuator electrodes and the contact point. The method further includes forming an array of actuator electrodes in alignment with portions of the fixed actuator electrodes, which are sized and dimensioned to prevent the MEMS beam from collapsing on the fixed actuator electrodes after repeating cycling. The array of actuator electrodes are formed in direct contact with at least one of an underside of the MEMS beam and a surface of the fixed actuator electrodes. |
US09604835B2 |
Liquid dispensing appliance comprising a solid gas-adsorbent
A kit of parts for dispensing a liquid contained in a container is disclosed. The kit includes a pressure driven dispensing appliance. The pressure driven dispensing appliance has a device for receiving a container containing a liquid to be dispensed. The appliance also has a device for dispensing the liquid from the container, when mounted in the appliance, a chamber containing a solid adsorbent suitable for adsorbing air, and a device for fluidly connecting the chamber with the interior of the container, when mounted in the appliance. An air compressor releasibly connectable to the chamber is also included. |
US09604834B2 |
Filler element comprising a Trinox tube
A filler element includes a housing, a channel formed therein, a valve in the channel, an opening downstream from the valve that dispenses content into a container when the valve is open, a tube for fill-level adjustment, a controlled gas channel, and a collection space. The tube, which adjusts a fill level of content in the container, projects past the dispensing opening and extends into an interior of the container during filling thereof. This tube connects to a collection space separated from a content vat from which the content comes through the channel. To adjust the desired fill level, a gas pressure is applied to the interior through the tube, thereby displacing excess content from the container. The controlled gas channel permits the gas to enter the container interior. |
US09604832B2 |
Extraction component for a corkscrew and a corkscrew
An extraction component for a corkscrew, which comprises a helix that is intended to be screwed into a cork and to this end has a point, whereby the extraction component has means to connect it to other components of the corkscrew, characterized in that the centerline of at least the part of the helix immediately after the point is in a direction that makes a first angle with a straight line that runs through the center of the means and the end of the helix, where the point is located. |
US09604831B2 |
Portable lifting jack stabilizer apparatus and method
A stabilizer apparatus operable with a jack device that includes a jack device base and a vertical member is provided. The stabilizer apparatus includes a stabilization base, which has a surface area greater than the surface area of the jack device base. The stabilizer apparatus stabilization base also includes a receiver section that is configured to removably receive the base of the jack device and couple the jack device to the stabilizer apparatus. The stabilizer apparatus further includes a stabilizing system configured to counteract a side load applied to a lifting end of the jack device while the jack device supports a load during a lifting operation. Related methods and systems are also provided. |
US09604830B2 |
Clamping apparatus
A clamping apparatus includes a frame adapted for mounting on a forklift so as to be raised and lowered along a mast of the forklift, a carriage supported by the frame for movement with respect to the frame in the widthwise direction of the forklift, two lifting arms supported by the carriage and extending in the widthwise direction of the frame, and a drive mechanism operatively connected to one of the lifting arms for producing relative movement of the lifting arms in the fore-and-aft direction of the frame to enable the lifting arms to grasp and release a load. The clamping apparatus can lift a portion of the objects in a closely-spaced layer and remove them from the layer without disturbing other objects in the layer. The clamping apparatus is particularly suitable for handling buckets. |
US09604828B1 |
Heavy equipment lifting
Heavy equipment is attached to slings and lifted by rollers raised and lowered in a structure with four pillars. Rollers prevent torque and provide vertical vectors. Roller axle supports move along the pillars. Two gantry crane frames are joined by cross and truss beams. Hydraulic jacks and pneumatic locks are controlled and sensed movements are communicated to processors for each pillar. One master processor communicates with a remote control. Sensors check lock and hydraulic cylinder position and allow roller movements only when positions are correct and all processors agree. |
US09604827B2 |
Mobile winch in a bag system
A mobile winching system is provided, whereby a motorized winch, battery, and controller are mounted on a metal plate that is attached to and may be enclosed within a bag, wherein the metal plate has attachment points for coupling an anchor component to fix the winch system in position during a winching operation. The mobile winch in a bag system provides a way to transport and operate a winch in areas that are otherwise inaccessible by traditional vehicle mounted winches without the necessity of separately transporting the components of the system and with reduced setup of the components for use. |
US09604826B2 |
Low profile roller fairlead
A fairlead assembly includes a frame structure having an opening therein. A pair of rollers are disposed on opposite sides of the opening. The frame structure includes a pair of opposed curved surfaces disposed between the end portions of the pair of rollers and defining a bordering surface of the opening. The frame can be cast as a unitary structure with the pair of rollers each rotatably supported by a support pin having opposite ends received in a first set of corresponding semi-cylindrical recesses in a surface of the cast frame. A clamp structure having a second set of corresponding semi-cylindrical recesses secure the support pins to the cast frame. |
US09604824B2 |
Clamp and trolley system
The invention provides a clamp and trolley system for moveably attaching a power cable, hose or tube (104) of a lifting apparatus to a guiding cable or track, the clamp 100) comprising: a first clamp component (102) having a first engagement surface (106,116) adapted to engage with the power cable, hose or tube (104); and a second clamp component (114) having a second engagement surface (132,133) adapted to engage with the power cable, hose or tube, the second clamp component (114) being pivotally attachable to the first clamp component and rigidly fastenable to it in a range of relative orientations; wherein the first and second engagement surfaces (106,116;132,233) are shaped so as to clamp the power cable, hose or tube (104) between the first (102) and second (114) clamp components as the second clamp component (124) is pivoted towards a more closed orientation. |
US09604822B2 |
Elevator
An elevator includes at least one elevator car driving in an elevator shaft driven by an elevator drive. The elevator car has at least one car door and a door sill at the bottom of the car door, which door sill includes at least one groove, in which the car door is guided, in which groove at least one trash hole is located to prevent trash from accumulating in the groove, whereby the elevator car further includes a toe guard which extends downwards from the door sill. The trash hole is connected with a first upper end of an air channel extending downwards from the door sill and includes at least one channel portion extending with a direction component in a horizontal direction and/or having an opening directed sideward, which air channel is connected with the toe guard. The elevator leads to a reduced noise generation in the region of the door sill, particularly in elevator cars traveling with a high speed. |
US09604820B2 |
Method and elevator arrangement
Method and arrangement in the manufacture of an elevator, which includes during construction time an elevator hoistway, an elevator car, hoisting roping, a supporting structure including a plurality of support elements movable between a position extended from the supporting structure towards the side and a position retracted towards the supporting structure, and a platform. A plurality of lifts are performed, in each of which lifts the supporting structure is lifted higher up in the elevator hoistway, while the support elements are in the retracted position, after which the support elements are displaced into the extended position and the supporting structure is lowered to rest on top of the structures of the building supported by the support elements in the extended position for the vertical support of the supporting structure in the elevator hoistway, and between lifts the elevator car is used for transporting passengers and/or freight between floors. |
US09604816B2 |
Bobbin holder adapter
A bobbin holder adapter facilitates replacing bobbins in a yarn feeding system called a creel, and which is formed by bearing of a constant lower table and a movable upper table on a central shaft. Further, a motion restriction component is positioned on the upper table for restricting the motion of the upper table around the central shaft bearing the upper table and for stopping the adapter at the desired point, a motion restriction housing is formed on the lower table for enabling movement of the motion restriction component, a locking ball is provided for keeping the adapter in the optimum position for unreeling yarn, a locking spring is positioned on the upper table for applying force on the locking ball, and a locking housing is formed on the lower table, on which the locking ball makes pressure as a result of the force applied by the locking spring. |
US09604815B2 |
Sheet folding device
A sheet folding device includes: a sheet receiving unit with a pair of guide plates to restrict opposite sides of one or a plurality of stacked sheets and a striking portion to be struck by leading ends of the introduced sheets; a roller group to introduce the sheets into the sheet receiving unit, strike the introduced sheets on the striking portion to form a bent portion on the sheets, and nip and fold the formed bent portion and discharge the sheets from the sheet receiving unit; and a curve forming unit to form a curved portion on the sheets, at a position closer to the leading ends of the sheets than a position where the bent portion to be folded by the roller group is formed, the curved portion being curved in a width direction perpendicular to a direction of transfer of the sheets. |
US09604811B2 |
Automatic paper product dispenser with data collection and method
Sheet product dispensers and methods are provided. A sheet product dispenser includes a loading station for sheet material, a sheet feeding mechanism configured to feed the sheet material, a presentation station for presenting one or more discrete sheet products to an end user, a sensor downstream of the feeding mechanism and upstream of the presentation station configured to detect a presence of the discrete sheet products, and a controller configured to facilitate dispensing of the one or more discrete sheet products in response to a signal, and to determine and store data associated with the dispensing of the sheet products. |
US09604809B2 |
Film roll/bag-on-a-roll making machine
A film roll/bags-on-a-roll making machine includes a feeding unit for transferring a film/sheet of bags, a reel displacement unit for cycling a reel through a reel let-off position, a reel-supplying position, a film-rolling position and a film-cutting position for enabling the reel to roll up the film/sheet of bags into a film roll/bags-on-a-roll, a cutting device for cutting off the feeding film/sheet of bags from the film roll/bags-on-a-roll at the reel that is cycled to the film-cutting position, and a control unit for controlling the operation of the feeding unit, the reel displacement unit and the cutting device. |
US09604808B2 |
Glass substrate comprising an edge web portion
A glass ribbon coated with a flexible material, the flexible coating forming a flexible web portion that extends from an edge of the glass ribbon at least one millimeter. The flexible web portion can be used to facilitate handling of the glass ribbon in a manufacturing process, and may include registration markings, or perforations, that further facilitate precise positioning of the ribbon. |
US09604803B2 |
Push-pull latch assembly for a detachable media pick mechanism
A push-pull latch assembly for a detachable media pick mechanism. The latch assembly comprises a handle that is slidably and axially insertable into a handle base which is mounted to the pick mechanism housing. The handle base includes a pair of cantilevered, opposed latched arms having opposed catches for engagement with a groove positioned inboard a free end of a cantilevered drive shaft for the pick mechanism. The handle includes triangular rails having inner and outer ramps used to separate the opposed latch arms. The outer ramp separates the latch arms when the handle is inserted into the handle base. The inner ramp separates the latch arms during removal of the pick mechanism from the drive shaft. An axial pushing force engages the latch assembly to the groove and an axial pulling force disengages the latch assembly from the groove allowing for pick assembly removal. |
US09604802B1 |
Removable media tray having a media restraint with translating and pivoting latching cams operable without the use of pinching
A media restraint for a removable media tray and slidably operable without the use of a pinching force. The media restraint slidably positionable on a track in a removable media tray and is operable without pinching. A pair of latching cams are used to engage the media restraint to the track and have serrated portions pivotally mounted to a bottom of the media restraint. The media restraint is operable by a finger of the user applying a downward force to the media restraint allowing a rack and pinion to horizontally translate a rack portion of the pair of latching cams away from the track and pivot the serrated portions away from the track and allowing the media restraint to be moved along the track. Upon removal of the downward force, a biasing member translates the latching cams back to reengage with the track. |
US09604801B2 |
Sheet transport apparatus and image recording apparatus
A sheet transport apparatus includes a first casing in which a transport path is formed; a transport unit which transports a sheet along the transport path; a second casing which is provided to be movable with respect to the first casing; a sheet support unit which is rotatably provided in the first casing at a position on a side to which the second casing is moved, the sheet support unit being changeable between a first state, a second state, and a third state and supporting the sheet at least in the third state; and an urging unit which urges the sheet support unit toward the first state within a range from the first state to the second state and which urges the sheet support unit toward the third state within a range from the second state to the third state. |
US09604799B2 |
Dock leveler sealing assembly
A sealing assembly for a dock leveler comprises two side restraints mounted on a loading dock along respective left and right sides of the vertical face of the dock leveler. A bottom restraint is mounted on the loading dock below the vertical face of the dock leveler. A mat is removably insertable between the side restraints. The mat is sized to allow left and right edges of the mat to engage the side restraints when inserted therebetween. The mat is foldable to define a vertical portion that covers the vertical face of the dock leveler and a horizontal portion that covers at least part of the horizontal face of the dock leveler. The mat substantially restricts airflow into and out of the loading dock through the gaps when the vertical portion of the mat is inserted between the side restraints such that a bottom edge of the vertical portion of the mat engages the bottom restraint, and the loading dock door closes atop of the horizontal portion of the mat. |
US09604798B2 |
Transportation system
A high-speed transportation system includes at least one transportation structure having at least one track, at least one capsule configured for travel through the at least one structure between a plurality of stations, a propulsion system adapted to propel the at least one capsule through the structure, and a levitation system adapted to levitate the capsule within the structure. At least one track is positioned to provide balancing force vectors to achieve stability for the capsule. |
US09604797B2 |
Apparatus and process for unloading load items from a loading space
An apparatus for unloading load items, comprising a receiving conveyor having a freely projecting receiving end and a rear delivery end, a removal conveyor and a transfer conveyor arranged therebetween which has a front takeover end adjoining the delivery end of the receiving conveyor and a rear handover end adjoining a head end of the removal conveyor, wherein the transfer conveyor is mounted so as to be pivotable in height about a first swivelling axis arranged at the handover end, and the receiving conveyor is mounted so as to be pivotable in height about a second swivelling axis arranged at the delivery end, wherein the receiving conveyor and the transfer conveyor can be moved, by being swivelled about the first and second swivelling axes, into at least one upper unloading position, in which the transfer conveyor is substantially horizontal before the first swivelling axis, the receiving conveyor is substantially vertical below the second swivelling axis and the receiving end of the receiving conveyor is on the floor of the loading space, or into at least one lower unloading position, in which the receiving conveyor and the transfer conveyor are at an angle of no more than 10°, 20°, 30° or 40° to the horizontal and the receiving end of the receiving conveyor is located on the floor of the loading space, and unloading processes using the apparatus. |
US09604796B2 |
Overhead conveyor system
The present disclosure provides a system for transporting work pieces from one location to another. The system uses either magnetic force or vacuum, or both, to lift and retain the work pieces against the moving overhead conveyor belt. The system can interrupt the magnetic force and/or the vacuum to release the work pieces from against the moving overhead conveyor belt at a desired transport location. |
US09604795B2 |
Transport device for conveying products
The transport device for conveying products comprises at least one pair of movable slides and an endless guide rail for guiding the at least one pair of slides, one behind the other, in a variable conveying direction. A linear motor drive device serves to drive the at least one pair of slides. A retaining element is provided on each of the two slides, wherein the retaining elements of the first slide and of the second slide form a product receiving space between them. The retaining elements on the first and second slides are each rotatably supported around a rotational axis, which is substantially perpendicular to the variable conveying direction. At least one connecting element is provided to connect the retaining elements of the first and second slides together in such a way that the relative orientation of the retaining elements to each other is determined. |
US09604793B2 |
Resin delivery system with air flow regulator
Apparatus and methods for conveying granular plastic resin from a supply to receivers that retain and dispense the resin when needed by process machine include a vacuum pump, an air flow limiter connected to the suction head of the vacuum pump, a first conduit connecting the receivers to the air flow limiter, and a second conduit connecting the resin supply to the receivers. |
US09604792B2 |
Device for transferring products from a feeder conveyor belt to a discharge conveyor belt using grippers, and method for operating the device
The invention relates to a device for transferring products from a feeder conveyor belt (10) to a discharge conveyor belt (12), comprising a linear motor having conveyor elements (14) which are movably guided on a guide and have grippers (18) for the temporary accommodation of products (20). The guide is designed as a linear guide section (13), and the conveyor elements (14) can be moved back and forth on the guide section (13) for picking up and putting down the products (20). When products (20) are conveyed consecutively in a row in the conveying direction (z) of the feeder conveyor belt (10), the feeder conveyor belt (10), the discharge conveyor belt (12) and the guide section (13) are arranged in parallel next to one another, at least in one lateral overlapping area. When products (20) are conveyed side-by-side in rows in the conveying direction (z) of the feeder conveyor belt (10), the feeder conveyor belt (10) is arranged perpendicular to the discharge conveyor belt (12), and the discharge conveyor belt (12) and the guide section (13) are arranged in parallel to one another and are arranged side-by-side with the feeder conveyor belt (10) at least in a lateral overlapping area. |
US09604789B2 |
Guide rail
Guide rail for an easy to clean conveyor, where the guide rail is adapted to have a straight position, in which position the guide rail is adapted to support a conveyor chain, and a folded position spaced apart from the straight position, where the guide rail comprises an upper support part adapted to glidingly support a conveyor chain, and a lower attachment part adapted to attach the guide rail to a holder, where the lower attachment part is adapted to allow the guide rail to pivot in the holder between the straight position and the folded position. In this way, a guide rail that allows for an easy cleaning of a conveyor is provided for. Such conveyors are e.g. used in the food industry. |
US09604788B2 |
Freewheel assist for a spiral conveyor belt system
A spiral conveyor belt system generally includes a rotatable cage, a first drive mechanism for rotating the cage about an axis in a first direction, an endless conveyor belt supported by the cage and a rotatable free wheel. The cage drives the conveyor belt along a helical path in a first direction and the rotatable free wheel rotates about an axis in a second direction opposite the first direction for guiding the endless conveyor belt from the cage along a return path and back to the cage. A second drive mechanism is preferably provided for rotating the free wheel. |
US09604787B1 |
Adjustable conveyor systems
Example adjustable conveyor systems are disclosed herein. An example adjustable conveyor system includes a first conveyor having a first conveying surface facing upward and running lengthwise along a first longitudinal axis and a second conveyor having a second conveying surface facing upward and running lengthwise along a second longitudinal axis. The second conveyor is spaced apart from the first conveyor to define a span between the first conveyor and the second conveyor. The second conveyor is pivotal relative to the first conveyor. A first side guide protrudes upward and extends lengthwise between the first conveyor and the second conveyor proximate the span, where the first side guide has a first adjustable length. A second side guide protrudes upward and extends lengthwise between the first conveyor and the second conveyor proximate the span, where the second side guide has a second adjustable length. The first side guide is spaced apart from the second side guide to define a passageway between the first conveyor and the second conveyor. The first adjustable length automatically lengthens and the second adjustable length automatically shortens in reaction to the second conveyor pivoting relative to the first conveyor. |
US09604785B1 |
Telescoping flow control discharge spout assembly for a conveyor of granular material
An auger conveyor for granular material or grain has a discharge outlet portion which pivotally supports a tubular inner spout section of a telescoping spout assembly. The inner spout section is pivoted by a remotely controlled actuator between an outwardly projecting upper discharge position and a downwardly projecting lower discharge position. The assembly includes an outer tubular spout section supported by the inner spout section for telescoping movement on the inner spout section, and an actuator in the form of an elongated link member pivotally connects the outer spout section to the conveyor outlet portion to produce the telescoping movement of the outer spout section in response to pivoting of the inner spout section. The spout assembly maintains a substantially constant vertical height while moving between the upper and lower discharge positions to avoid interference with a container receiving the grain. |
US09604783B2 |
System and method for maintaining a minimum separation between pallets positioned on adjacent racks
A system is provided for maintaining a minimum separation between a first pallet positioned on a first rack and a second pallet positioned on a second rack. The system comprises a double back stop that includes a first back stop attached to the first rack to prevent lateral movement of the first pallet beyond the first back stop. The double back stop also includes a second back stop attached to the second rack to prevent lateral movement of the second pallet beyond the second back stop. A minimum distance is maintained between the first and second backstops such that the minimum separation is maintained. The double back stop also includes a middle section to connect the first back stop to the second back stop. Methods are also provided for forming the double back stop and for maintaining the minimum separation between the first pallet and the second pallet. |
US09604782B2 |
Semi-automatic and/or fully-automatic order-picking system
The present invention relates to a semi-automatic and/or fully automatic order-picking system and a corresponding apparatus and a method which facilitates efficient order picking at low technical outlay. |
US09604781B2 |
Picking station with automated warehouse
A method of filling orders and order fulfillment system includes storing inventory receptacles in an automated warehouse, some having a plurality of different types of inventory items. A queue of orders is maintained in a computer system, each including at least one inventory item. Each order is selected from the queue and assigned to a pick station. The computer system retrieves inventory receptacle(s) from the automated warehouse for the selected order and supplies the receptacle(s) to the pick station. The computer system identifies to an operator which inventory item is to be segregated with the selected order in at least one put receptacle. One or more of the put receptacles receives inventory items for at least one individual order and is directed to a secondary order processing station where items are separated into individual orders. The operator may be provided the capability to consolidate inventory items from inventory receptacles while picking orders to consolidate partially filled inventory receptacles in a consolidated inventory receptacle. |
US09604777B2 |
Water storage structure
A water storage structure includes an impermeable layer including a plurality of hydrophobic particles, a water retentive layer provided on the impermeable layer and capable of holding a predetermined volume of liquid, and a pavement layer provided on the water retentive layer and including a tube penetrating from a first surface to a second surface. |
US09604773B2 |
Insert with nozzle formed by micro stepped and conical surfaces
An actuator which comprises an actuator outlet, a post located within the actuator outlet which extends normal to a base surface of the actuator outlet, and the post comprises diametrically opposed first and second alignment protrusions. An insert is mounted and securely retained within the actuator outlet by an interference fit and the base of the insert has a discharge nozzle formed therein. First and second alignment protrusions space the insert away from the post and define a partially restricted flow passages while unobstructed product flow passages are defined one either side of the second alignment protrusions. The first and second stepped shoulders are axially respectively aligned with the first partially restricted flow passage while the first and second conical surface are respectively axially aligned with unobstructed flow passages so that the product to be dispensed, upon being discharged, is sprayed by the nozzle in a fan spray pattern. |
US09604771B1 |
Tool holder
A tool holder contains: a connector and a fixer. The connector includes at least one body, and each body has a first side plate and a second side plate. The connector also includes a fixing mount connecting with the first side plate and the second side plate. The first side plate has a first fitting portion, and the second side plate has a second fitting portion. The first fitting portion and the second fitting portion define a fitting zone, and the first side plate further has a first locking projection. Among the first side plate, the second side plate and the fixing mount is defined a cavity. The fixer is housed in the cavity of the connector to limit the first side plate and the second side plate to drive the first fitting portion and the second fitting portion to deform. |
US09604765B2 |
Locking cap device and methods
A cap device and methods for use with a container are provided. The cap device can include a piercer cover and a shell for comprising a composition. The piercer cover has one or more side walls comprising one or more piercers attached to the top wall and disposed toward the bottom portion of the piercer cover for breaking a film covering the bottom portion of the shell. |
US09604762B2 |
Plug structure
A plug structure for taking out liquid from a container includes a plug body press-fitted into a container inlet port. The plug body is resiliently deformable with a lower portion being formed into a ring shape and being provided with slits in an axial direction. The plug structure includes a locking claw on an outer peripheral surface of the plug body, which projects toward an inner wall surface of the container inlet port. The locking claw has a minimum diameter substantially the same as or smaller than the inner diameter of the container inlet port. The locking claw has a maximum diameter that is larger than the inner diameter of the container inlet port. The plug structure includes a valve operating portion that presses a valve on a socket connected to the plug body. The valve operating portion is provided on an upper end inlet port of the siphon tube. |
US09604757B2 |
Reusable bag holder and system and method of using the same
A reusable shopping bag holder and system and method of using a reusable shopping bag holder and system is disclosed herein. The system includes a primary bag and a plurality of flexible secondary bags. The primary bag includes a plurality of compartments formed by dividers or pockets. The compartments store the secondary bags such that the secondary bags can be removed from the primary bag as necessary to store and carry shopping items. The primary bag itself may also be used to carry shopping items. |
US09604756B1 |
Process for testing a compressor or a combustor of a gas turbine engine using a large compressed air storage reservoir
A process for testing a combustor of a gas turbine engine, where a large volume of compressed air is stored in a large reservoir of at least 10,000 m3 such as an underground storage cavern, compressed air from the storage reservoir is passed through heat exchanger to preheat the compressed air to a temperature that would normally be discharged from a compressor, the preheated compressed air is burned with a fuel in the combustor, and additional compressed air from the reservoir is passed through an injector located downstream from the combustor to produce a decreased pressure such that a low atmospheric condition at the combustor exit is simulated. |
US09604755B2 |
Assembly pallet
An assembly pallet is assembled a cell stack to. The cell stack that includes a cell group in which a plurality of electric cells are stacked, end plates arranged in a position between which the cell group is interposed, and a restraining member for applying a restraint that restrains the cell group to the end plates. The assembly pallet includes a positioning engagement member that is engaged with the restraining member to effect positioning of the cell stack. |
US09604747B2 |
Compartmented beverage bottle
A compartmented bottle has a primary compartment and at least one secondary compartment. The primary compartment has an exhaust aperture and an inlet aperture, and the secondary compartment has a secondary exhaust aperture. The inlet aperture of the primary compartment and the secondary exhaust aperture of the secondary compartment are fluidically connected by an inter-compartmental conduit, and a selectively actuated inter-compartmental valve is disposed in the conduit. The valve, which could comprise a cylindrical valve, has a closed condition wherein the secondary compartment is sealed and an open condition wherein the secondary compartment is in fluidic communication with the primary compartment. A toroidal collar can bridge an annular channel between the primary and secondary compartments to establish a continuous cylindrical surface. The valve can be operated by a handle disposed at a distal end of an actuation rod that is drivingly engaged with the inter-compartmental valve. |
US09604746B2 |
Bottle made of polymer material
A bottle made of polymer material includes a base provided with a plurality of ribs. Each rib is composed of a curvature of the base of the bottle which forms a protuberance in the longitudinal direction directed towards the inside of the bottle. The ribs extend in a radial direction along a line of radial extension. The bottle is characterized in that the projection, in a transverse plane, of the line of radial extension of at least one of said ribs is curved. |
US09604743B2 |
Device for forming packaging units
An apparatus for producing a container pack includes a linear transporter, applicator elements, and head guides. The linear transporter has first, second, and third sections. Transport surfaces run parallel to one another in said first section, are oriented at an angle to one another in said second section, and again run parallel to one another in said third section. The second section comprises applicator elements having transversely displaceable and rotatable head guides for single-container transport along said three sections. The apparatus is configured to bring containers together in said third section to form said pack and to transport said pack towards a discharge side. |
US09604739B2 |
Compact case with cake retention pan
A cosmetic compact has a pan made from an elastomeric material. The pan is elastically biased to a size that is smaller than a pre-formed cake of cosmetic product. The empty pan is temporarily expanded by applying vacuum to a bottom and sidewalls of the pan. The cake of cosmetic is inserted in the expanded pan and the pan is released from the vacuum. The pan contracts toward the smaller size and thus traps and holds the cake in the compact. |
US09604737B2 |
Directionally controlled elastically deployable roll-out solar array
A directionally-controlled roll-out elastically deployable solar array structure is disclosed. The structure includes one or more longitudinal elastic roll out booms that may be closed section or open section to allow for efficient rolled packaging onto a lateral mandrel. A flexible photovoltaic blanket is attached to a tip structure and to a lateral base support structure, but remains uncoupled from the longitudinal booms. The solar array system may be stowed simultaneously into a rolled package comprised of the roll out booms and the flexible planar blanket together, or onto independent rolls. Alternatively, the system may be stowed by rolling the booms, and accordion Z-folding the hinged flexible photovoltaic blanket into a flat stack. Structural deployment is motivated by the elastic strain energy of the roll out booms, and several methods of deployment direction control are provided to ensure a known, controlled, and unidirectional deployment path of the elastically unrolling booms. |
US09604731B2 |
Measurement system for measuring the velocity of an aircraft
The disclosure herein relates to a measurement system to measure characteristics of the velocity vector of an aircraft in relation to a surrounding air mass, the measurement system comprising—a frontal surface of the aircraft, two primary sensors, each being fixed to the frontal surface of the aircraft and able to deliver an output value relating to the deformation experienced by the sensor, and a processing unit able to receive the output values and able to calculate the angle of attack and/or the velocity of the aircraft on the basis of these output values. |
US09604725B2 |
Aircraft seat with a single-beam structure and aircraft comprising such a seat
An aircraft seat includes a seat bucket that is integral by its seatback with a single beam oriented along an axis that is approximately perpendicular to the aircraft floor, which beam is integral with fastening points located on at least two separate lines on the aircraft floor. |
US09604724B2 |
Seating arrangement convertible to a bunk bed
A seating arrangement includes a seat with a seating surface and a top bunk disposed adjacent to the seat. The seat and the top bunk are configurable between a first configuration and a second configuration. In the first configuration, the seat accommodates a user in a seated position and the top bunk is stowed. In the second configuration, the seat and the top bunk form a bunk bed configured to accommodate users in prone positions. In the first configuration, the seating surface is disposed at a first predetermined height. In addition, in the second configuration, the seating surface is disposed at a second predetermined height that is lower than the first predetermined height. |
US09604718B2 |
Method and device for generating at least one set point from a flight control set point, a motor control set point and an aircraft guidance set point, related computer program product and aircraft
A method and device for generating at least one set point from a flight control set point, a motor control set point and an aircraft guidance set point, a related computer program product and an aircraft are disclosed. In one aspect, the method includes acquiring a mechanical property relative to at least one corresponding primary control member and computing at least one set point from among one or more primary set points and one or more secondary set points. The method also includes generating at least one of the computed set point(s) and switching, based on the mechanical property acquired for the corresponding primary control member, between a first mode in which one or more primary set points are generated and a second mode in which one or more secondary set points are generated. |
US09604717B2 |
Systems and methods for operating flight control surfaces
Systems and methods for operating flight control surfaces are provided. One system includes a control device having a two piece shaft including a first shaft portion and a second shaft portion, a spline key detachably coupling the first shaft portion and the second shaft portion, and a crankshaft operatively coupling the two piece shaft and a flight control surface. The control device further includes a driving mechanism coupled to the spline key and operable to move the spline key to engage and disengage the first and second shaft portions, wherein the first and second shaft portions are disengaged when a failure to the flight control surface is detected, causing the second shaft portion to drive the flight control surface to a safe position. |
US09604715B2 |
Solar powered aircraft with a variable geometry wing and telecommunications networks utilizing such aircraft
A solar powered aircraft having segmented wings that can be reconfigured during flight to optimize collection of solar energy are described. The aircraft have rigid construction that is resistant to inclement weather and is configured to rely on free flight control at high altitude and under conventional conditions, thereby providing flight duration in excess of 2 months. The aircraft is particularly suitable for use as part of a telecommunications network. A telecommunications network incorporating such aircraft is also discussed. |
US09604713B2 |
Door migration prevention system
According to some embodiments, a door system includes a door attachment device and a receiver. The door attachment device may be coupled to a door, and the receiver may be coupled to a door frame. A receiving surface of the receiver may be configured to at least partially receive the door attachment device along a first axis. The receiving surface may have a non-planar portion curved relative to the first axis such that the receiving surface responds to movement of the door attachment device in a direction parallel to a second axis, the second axis perpendicular to the first axis, by repositioning the door attachment device in a third direction perpendicular to the plane formed by the first axis and the second axis. |
US09604709B2 |
Boat lift
A floating boat lift having flotation tanks positioned under sides of a frame of the boat lift. Water flow is regulated so that tanks fill from near the center of the boat lift. A preferred hingeable connection of the boat lift to a bulkhead, along with lateral stabilization, participates in maintaining a generally horizontal attitude for the boat lift. Water is accepted into or pumped from the flotation tanks, allowing the frame of the boat lift to fall or rise relative to the surface of the water. One or more catwalks along the sides of the boat lift and connected to the bulkhead may float, but at a level that is independent of the boat lift frame. |
US09604707B2 |
Ride-height adjustable air shock boat seat pedestal with locking swivel
A ride height adjustable oil damped air shock boat seat pedestal with selectively lockable swivel capability is shown, which includes a locking pin extending below the seat and moving up and down with the seat as permitted and controlled by the air shock. The locking pin being received by a structure, which limits rotation of the seat. |
US09604706B2 |
Ship for supplying liquified fuel gas
A ship for bunkering liquefied fuel gas to a liquefied-fuel-gas propulsion ship includes: a liquefied-fuel-gas storage tank installed in the ship; a fuel supply pipe connected to the liquefied-fuel-gas storage tank and supplying fuel to the liquefied-fuel-gas propulsion ship; and a BOG collection pipe collecting BOG produced in a liquefied fuel gas tank of the liquefied-fuel-gas propulsion ship. |
US09604703B2 |
Rail mounting system
The invention relates to a watercraft mounting system that embodies a multi-faceted tube and a mating clamp system adapted to carry an accessory. The designs of the railing and clamp have geometry to prevent rotation while allowing flexibility of adjustment in multiple positions. |
US09604701B2 |
Marine seismic surveying in icy or obstructed waters
A marine seismic surveying apparatus for obstructed waters includes a deployed device and a buoy. The deployed device is disposed at an end of a streamer and is towed below a surface of water. The buoy extends from the end of the streamer to the water's surface. A coupling connects the buoy to the end of the streamer and is breakable due to tension from the buoy obstructed at the surface of the water. A receiver associated with the buoy obtains location information via the buoy at the water's surface. The deployed device can reckon its location with an inertial navigation system in place of location information obtained with the buoy's receiver. Also, the buoy can be deployed at the surface of the water, and more than one buoy can be available for deployment should one be lost. |
US09604694B2 |
Hydraulic shock absorber and method for injecting operating liquid into hydraulic shock absorber
A hydraulic shock absorber includes a cylinder connected to a wheel side, a liquid chamber formed in the cylinder and filled with an operating liquid, an annular rod guide fixed to the cylinder and closing a vehicle body side of the liquid chamber, a piston rod connected to the vehicle body side, penetrating a shaft core part of the rod guide, and going into/out of the cylinder, a piston held by the piston rod and dividing the liquid chamber into an extension-side chamber and a compression-side chamber, and an annular bush fitted in an inner periphery of the rod guide and pivotally supporting the piston rod, movably in an axial direction, in which the piston rod includes a columnar sliding shaft portion in sliding contact with the bush and a first injection portion for injecting the operating liquid provided on a side opposite to the piston of the sliding shaft portion and outside a range of a damper stroke. |
US09604689B2 |
Bicycle frame joint locking mechanism
An apparatus, includes a first pair of brackets coupled to a first bicycle frame component, and one of the first pair of brackets has a radially-inwardly extending first protrusion. The apparatus includes a first gear component coupled to a second bicycle frame component, and the gear component is rotatably coupled within the first pair of brackets. The first gear component has a first set of recesses radially spaced from each other about a periphery thereof. The apparatus further includes a first clamping component engaging at least one of the first pair of brackets and selectively biasing the first protrusion into one of the first set of recesses to rotatably lock the first gear component with respect to the first pair of brackets. |
US09604687B2 |
Vehicle
At least a portion of a detecting portion of a front wheel rotation speed detector is supported on one front telescopic element of a shock absorbing device and is positioned in, as viewed in the direction of a wheel axis, an area defined by a front imaginary line which passes a front end of the shock absorbing device and which is parallel to a steering axis and a rear imaginary line which passes a rear end of the shock absorbing device and which is parallel to the steering axis in a perpendicular or substantially perpendicular direction to the wheel axis and the steering axis, an area located inwards of an outer shape of a wheel, and an area which is located outside an area defined between the front and rear telescopic elements. |
US09604676B2 |
Method of providing a corrosion barrier between dissimilar metals with an epoxy insulator
A method for providing a corrosion-resistant barrier between bolted dissimilar metals comprising the steps of disposing epoxy adhesive tape on at least one of a first and second metal member, curing the epoxy adhesive tape, applying a corrosion-resistant layer to the first and second metal members, and bolting the first and second metal members together such that the cured epoxy adhesive tape is positioned between the first and second metal members. |
US09604665B2 |
Characterization of stiction condition in a manual steering gear
A method for characterizing a stiction condition in a manual steering gear includes transmitting a steering input control signal to a rotary actuator, and rotating a steering shaft with constant acceleration, via the rotary actuator, in response to the steering input control signal. A steering output torque is determined while rotating the steering shaft with the constant acceleration, receiving the steering output torque via the controller, and executing a control action when a rate of the received steering output torque exceeds a threshold rate indicative of the stiction condition. A system includes a rotary actuator, a manual steering gear having a steering shaft connected to the rotary actuator, a torque transducer for measuring a steering output torque imparted to the steering shaft by the actuator, and a controller programmed as set forth above. |
US09604658B2 |
Collapsible laundry and accessory basket with wheeled and carryable configurations
A wheeled enclosure having an interior volume defining body including a rigid base and a plurality of upwardly extending and flexible sides. A plurality of wheeled supports are incorporated into the rigid base. A telescoping handle extends from a rear of the body and may be secured to an edge of the rigid base. Other features include the provision of rigid inserts which are seated within vertical pockets integrated into each of four interconnecting sides associated with a flexible body. The flexible body can include an upper half which reverse folds into an interior defined by the lower half and the rigid inserts. The rigid base can also be foldable and can convert the assembly between expanded use and collapsed storage positions. |
US09604654B2 |
Arrangement for supplying a rail vehicle with electrical energy
The invention relates to an arrangement for supplying a rail vehicle with electrical energy. One electrical machine is allocated to each of at least two internal combustion engines for generating electrical energy. A common controller is designed to start the internal combustion engines individually as required. At least one pre-heating device is designed to pre-heat the internal combustion engines before a start. A temperature detection device is thermally coupled to the internal combustion engines. The controller is designed, during an operation of one of the internal combustion engines, to start another of the internal combustion engines if, due to cooling of the other internal combustion engine, a temperature of the other internal combustion engine detected by a temperature identifying device reaches or exceeds a temperature threshold. |
US09604649B1 |
Hands-off detection enhancement by means of a synthetic signal
A method and system for determining whether a driver of a vehicle is in contact with a steering wheel of the vehicle is provided. One embodiment of the method includes the steps of generating a perturbation signal that causes vibration of the steering wheel and receiving a steering signal from a steering system sensor configured to provide an indication of at least one of a steering torque and a steering movement of a component of an electronic power steering system of the vehicle. The method further includes the steps of mixing the perturbation signal and the steering signal to produce a heterodyne signal and generating a driver contact signal indicative of whether the driver of the vehicle is in contact with the steering wheel of the vehicle, the value of the driver contact signal dependent on characteristics of the heterodyne signal relating to the perturbation signal. |
US09604647B2 |
Method for detecting a lack of driver activity at the steering wheel of a motor vehicle
A method detects a lack of driver activity at the steering wheel of a motor vehicle. A moment imparted by hand to the steering wheel by the driver is repeatedly measured, and if in a plurality of successive measurements the magnitude of a value of the moment imparted by hand does not exceed a threshold value, a lack of driver activity is inferred. The magnitude of the threshold value is dependent on the surface condition, in particular on the degree of unevenness, of the roadway being traveled upon. The degree of unevenness of the roadway may be derived from a measured vertical acceleration in the wheel suspension of the vehicle or from deceleration and/or acceleration signals of at least one wheel of the vehicle. |
US09604642B2 |
Positioning autonomous vehicles based on field of view
Positioning autonomous vehicles based on field of view, including: identifying, by a vehicle management module, one or more critical sight lines for a subject vehicle, each critical sight line representing a boundary of an area of space surrounding the subject vehicle; determining, by the vehicle management module, physical location information for one or more surrounding vehicles; determining, by the vehicle management module in dependence upon the physical location information for one or more surrounding vehicles, whether one or more surrounding vehicles are located within the area of space surrounding the subject vehicle; and responsive to determining that one or more surrounding vehicles are located within the area of space surrounding the subject vehicle, altering a location of the subject vehicle relative to at least one of the surrounding vehicles. |
US09604633B2 |
Travel support device, travel support method, and drive support system
A travel route from the current location to the destination is divided into a plurality of sections. Travel modes of a vehicle include an EV mode, which uses the motor as the drive source, and an HV mode, which uses at least the internal combustion engine as the drive source. A road load for traveling each section in the EV mode is set. A travel support device includes a planner and a setter. The planner plans, for each section, the travel mode by selecting one of the EV mode, and an HV mode. When a planned section of the travel mode is switched from an EV mode-planned section to an HV mode-planned section, the setter sets the travel mode to continue traveling in the EV mode, on the condition that a remaining charge of the battery is less than a threshold. |
US09604632B2 |
Control system for hybrid vehicle
A vehicle control system is provided to reduce a change in drive force and to start an engine without delay when starting the engine by a motor during running. The control system is applied to a hybrid vehicle having an internal combustion engine and two motors supplied electric power from a battery. The control system comprises a determination means that determines a fact that a state of charge of the battery is lower than a first threshold, during propelling the vehicle by the two motors by supplying the electric power from the battery while stopping the engine (at step S2); and a drive force restriction means that restricts a total drive force of said two motors for propelling the vehicle to an allowable limit which is lower than a theoretical maximum drive force of said two motors, given that the state of charge of the battery is lower than a first threshold (at step S3). |
US09604630B2 |
Hybrid automobile and power system torque control method thereof
A hybrid system torque control method and hybrid automobile using same, the method comprising the following steps: (1) analyzing the torque required by a driver; (2) allocating and coordinating the multiple-source torque. The method ensures a consistent driving feel within the range of real-time power source torque capacity, and facilitates hybrid system matching. |
US09604629B2 |
Hybrid vehicle control device
A control device controlling a hybrid vehicle provided with a planetary gear mechanism including a first gear connected to a first rotary electric machine, a carrier connected to an engine shaft of an internal combustion engine, and a second gear connected to a drive shaft to which a second rotary electric machine is connected and a rotation blocking mechanism blocking the rotation of the engine shaft in the other direction adjusts the ratio of a first torque to a total torque based on the result of the determination of whether or not the temperature of a first gear mechanism satisfies a desired condition in a case where the hybrid vehicle travels in a dual drive traveling mode in which the hybrid vehicle travels by using both the first torque output by the first rotary electric machine and a second torque output by the second rotary electric machine in a state where the internal combustion engine is stopped. |
US09604626B2 |
Hybrid vehicle
An ECU performs a control process including the steps of: acquiring information about a gear, a vehicle speed, a depression amount of an accelerator pedal, and a transmission mode being selected; calculating a reference value; calculating a restriction value; calculating a target value of the SOC; calculating a required electric power value; and outputting a command value for the engine torque and respective torque command values for a first MG and a second MG. |
US09604625B2 |
Process for controlling a start-stop operation of a vehicle having a hybrid drive, and a corresponding vehicle
A process for controlling a vehicle start-stop operation having a hybrid drive with an internal-combustion engine and an electric motor, a service brake with an ABS and an electric parking brake, includes: determining, monitoring and analyzing performance parameters of the vehicle, the internal-combustion engine, the electric motor, the service brake and the parking brake; automatically releasing the parking brake in the case of a starting prompt because of determined performance parameters; driving the vehicle by the electric motor for the start; starting the engine by the electric motor if the engine is switched off; driving the vehicle by the electric motor and the engine; activating a generator operation of the electric motor in the case of a braking prompt because of determined performance parameters; activating the service brake; and automatically locking the electric parking brake when the vehicle is stopped after a previously definable deceleration time. |
US09604622B2 |
Electric braking system for vehicle
A vehicle electric braking device wherein: a first degree of contribution associated with the actual pressing force value and a second degree of contribution associated with an estimated pressing force value, are determined based on operation amount of a braking operation member; the second degree of contribution is determined to be larger than the first degree when the operation amount is small; the first degree of contribution is determined to be larger than the second when the operation amount is large; a combined pressing force is calculated based on a value obtained by accounting for the first degree of contribution in the actual pressing force value and a value obtained by accounting for the second degree of contribution in the estimated pressing force value; and an electric motor target power supply amount is calculated based on the combined pressing force and a target pressing force calculated from the operation amount. |
US09604621B2 |
Pressure regulating valve
A housing projection is formed at a bottom of a second reservoir hole in a housing. According to this, a tip side in a press-fitting direction of a sleeve tends to deform inwardly in a radial direction and escape from the housing in a process of press-fitting the sleeve 88 into the second reservoir hole, since an inner slant part of the tip side of the sleeve contacts to a contacting surface of the housing projection, deformation of the tip side of the sleeve 88 is suppressed. |
US09604620B2 |
Air dryer system for a locomotive with optimized purge air control
An air dryer system for a locomotive having optimized purge air control over a twin tower desiccant-type air dryer. The computer controlled locomotive brake system is used to determine when the air dryer is being used and approximately how much air flow has actually passed through the active tower of the dryer using the air consumption state, the change of pressure in the second main reservoir, the air compressor on/off state, the total accumulated time of air flow since last purge cycle, and/or the calculated air flow through the air dryer since the last purge cycle. When the actual air flow reaches the capacity of the active tower of the air dryer, the computer controlled locomotive brake system commands the air dryer to perform a purge cycle. The system thus maximizes the use of each tower in the air dryer rather than switching according to a preset time period. |
US09604618B2 |
Brake booster and method for its operation
A regulatable brake booster and to a method and a control unit for operating same. Using the method for operating the brake booster, as well as the embodiment of the brake booster, a reaction on a driver may be avoided or reduced by an offset of the brake pedal or by a changed operating force in response to a change in the supporting force. The change in the supporting force is particularly an adjustment of the braking effect of an hydraulic braking system to the braking effect of a regenerative braking system. |
US09604617B2 |
Hydraulic brake system
Disclosed is a hydraulic brake system comprising a master cylinder forming a braking hydraulic pressure according to an operation of a brake pedal, wheel brakes provided at a front wheel and a rear wheel, respectively, to provide a braking force by receiving the braking hydraulic pressure of the master cylinder, solenoid valves provided at an inlet side and an outlet side of each of the wheel brakes to control a flow of the braking hydraulic pressure, a low pressure accumulator temporarily storing oil discharged from the wheel brake during a pressure reducing braking in which the solenoid valve operates, a pump configured to compress oil stored in the low pressure accumulator such that the oil is discharged toward the wheel brake or the master cylinder according to a demand, and an orifice provided at an outlet side of the pump, wherein the orifice includes an outer case and an inner case provided to form a space between the outer case and the inner case while assembled to the outer case, a first oil passage passing through the inner case, and a second oil passage provided in the space between the outer case and the inner case, and the first oil passage and the second oil passage have lengths different from each other. |
US09604615B2 |
Method for carrying out a braking procedure in a vehicle
In a method for carrying out a braking procedure in a vehicle having a hydraulic brake system, when the brake temperature exceeds a boundary value hydraulic fluid is intermediately stored in a storage chamber, and when brake fading occurs the hydraulic fluid is pumped back into the brake circuit. |
US09604614B2 |
Method for operating a brake system, and brake system
A method and system for operating a brake system for motor vehicles, including a plurality of wheel brakes for which wheel-individual nominal pressure includes an electrically controllable pressure supply device, to provide a brake system pressure for actuating the wheel brakes. The brake system pressure provided by the pressure supply device can be determined. An electrically controllable inlet valve and electrically controllable outlet valve per wheel brake adjust wheel-individual brake pressures. At least one outlet valve is analogized for analog-controlled and is controlled by an electric control variable, wherein at least one valve-specific control characteristic and/or a valve-specific parameter is determined for the analogized or analog-controlled outlet valve by the brake system, and wherein the analogized or analog-controlled outlet valve is controlled as a function of the valve-specific control characteristic and/or the valve-specific parameter for the degradation of the brake pressure in the wheel brake associated with the outlet valve. |
US09604604B2 |
Vehicle washing installation
A vehicle washing installation having two stands on which a nozzle beam with a plurality of high-pressure nozzles is held so as be adjustable in height is provided. The nozzle beam is surrounded by a protective body extending along the nozzle beam and having at least one outlet opening for cleaning liquid, the protective body being adjustable in height together with the nozzle beam and being movable relative to the nozzle beam upon striking an obstacle, the movement of the protective body relative to the nozzle beam being detectable by a sensor assembly in order to provide a control signal. |
US09604599B2 |
Wiper blade device
The invention relates to a wiper blade device comprising a wiper blade adapter (10) and a wiper strip unit (12). According to the invention, said wiper strip unit (12) has at least one securing recess (14) which, in at least one operating state, forms an interlocking connection with the wiper blade adapter (10). |
US09604598B2 |
Wiper arm pin release for service
A wiper system wiper system for wiping a window is provided. The wiper system has an arm head and an arm retainer connected to the arm head via a pivot. The wiper system includes a latch for controlling pivoting of the arm retainer with respect to the arm head. The latch is configured to restrict pivoting of the arm retainer with respect to the arm head to an operating range close to the window when the latch is in a latched state. The latch is further configured to allow pivoting of the arm retainer with respect to the arm head from the operating range to a servicing position away from the window when the latch is in an unlatched state. |
US09604595B2 |
End-fitting tensioner for a safety belt system
An end fitting tensioner (10) for a seat belt system includes a rotatable belt shaft (12) to which one end (14) of a webbing (16) is fixed, a belt shaft housing (18) in which the belt shaft (12) is supported, a rope reel (36) which is arranged at an axial end of the belt shaft (12) and is connected to the belt shaft (12) in a rotationally fixed manner, as well as a pull rope (41) which is secured by one rope end (45) on the rope reel (36) and can at least partly be wound onto the rope reel (36). The rope reel (36) includes a winding surface (62) for the pull rope (41) that is conically tapered in the axial direction. |
US09604593B2 |
Safety belt device
Safety belt device, in particular for a motor vehicle, comprising a roll-up spindle rotatably supported in a frame, on which roll-up spindle a safety belt is held with its one end, wherein the roll-up spindle is biased into a roll-up position, in which the safety belt is rolled up on the roll-up spindle and the safety belt can be rolled off the roll-up spindle against the bias by rotating the roll-up spindle and wherein a torsion rod is provided in the roll-up spindle which is fastened to the roll-up spindle with a first end and which is fastened to the frame with a second end, wherein a plastic material is molded around the torsion rod in the roll-up spindle, wherein at least the second end of the torsion rod is free from the plastic material. |
US09604590B2 |
Side pillar assemblies with multi-surface retention structures for side airbags
A vehicle includes a pillar garnish mounted at a side pillar assembly of the vehicle. The pillar garnish has an upper end portion, a roof head lining with an outer portion that extends along the upper end portion of the pillar garnish, and an airbag jump bracket fixedly located between a pillar body and the roof head lining. The airbag jump bracket includes a first portion extending in a vehicle height direction and a second portion extending outwardly from the first portion in a vehicle width direction. The second portion supports an airbag body that guides the airbag body toward an occupant compartment of the vehicle during an airbag deployment event. The airbag jump bracket further includes an outwardly turned flange portion that extends outwardly in the vehicle width direction to underhang the second portion of the airbag jump bracket. The outwardly turned flange portion has an underside and terminates at an end located beneath the second portion of the airbag jump bracket. The pillar garnish includes an airbag jump bracket engaging feature including a tower engaging portion and a ledge engaging portion. The ledge engaging portion includes a ledge engaging surface that engages the outwardly turned flange portion during an airbag deployment event in the vehicle height direction and the tower engaging portion includes a tower engaging surface that engages the outwardly turned flange portion during an airbag deployment event in a vehicle width direction. |
US09604588B1 |
Rear row knee bolster deployment control
A system comprises a controller for a vehicle. The controller comprises a processor and a memory. The controller is configured to make readings of an infrared sensor positioned to sense objects and motion in a rear passenger foot well. The controller determines if there is an object present in the foot well using the readings. The controller then determines if there is motion in the foot well using the readings. The controller then activates a knee bolster when motion is determined, and deactivates a knee bolster when motion is not determined. |
US09604587B2 |
Occupant position detection device and airbag deployment control system
An occupant position detection device is an occupant position detection device disposed inside a vehicle to detect a position of an occupant, and includes: a detector comprising two or more sensor electrodes disposed forward of a seat and at least one sensor electrode disposed at a position more rearward and higher than these sensor electrodes, the detector respectively outputting a detection signal based on a distance between each of the sensor electrodes and the occupant; and a computation unit inputted with the detection signal to compute an occupant position. The computation unit selects from the detection signals outputted from the detector three or more types of combinations configured from two of the detection signals, calculates a ratio or difference for each of these combinations of detection signals, and computes the occupant position based on the three or more calculated ratios or differences of the detection signals. |
US09604585B2 |
Failure management in a vehicle
A system includes first and second failsafe devices. Each of the failsafe devices includes a processor and a memory. The memory stores instructions executable by the processor for performing at least one of detecting a fault and providing a communication concerning a fault. The system further includes an arbitration bus connecting the first and second failsafe devices. The communication concerning the fault may be provided from a first one of the first and second failsafe devices to a second one of the first and second failsafe devices. |
US09604583B2 |
Wheel resonator for vehicle
A wheel resonator for a vehicle may include a resonant plate which has an annular structure that is wound around a rim portion of a wheel while maintaining predetermined tension, has resonant holes formed at predetermined intervals in a circumferential direction, and forms a resonant chamber together with a surface of the rim portion, and sealing plates formed integrally with both end portions of the resonant plate, and tightly attached to and supported on an inner wall surface of the rim portion. |
US09604581B2 |
Vehicle vision system with color correction
A vision system for a vehicle includes a color camera disposed at a vehicle and having an exterior rearward field of view. The color camera includes an imaging array of photosensing pixels and at least one color filter disposed at or in front of at least some of the photosensing pixels. An image processor is operable to process image data captured by the color camera. Processing of captured image data by the image processor includes utilization of a color correction algorithm that includes a color correction matrix. The color correction matrix algorithm may utilize a 3×3 color correction matrix. The color correction algorithm may include a color correction matrix algorithm and a histogram algorithm that function to determine a color correction for the captured image data. |
US09604574B2 |
System and method for estimating driving lane of vehicle
A system for estimating a driving lane of a vehicle includes a road surface marking recognizing unit configured to recognize a road surface marking of a lane in which the vehicle is driving, a lane change determining unit configured to calculate a variation in a distance between the vehicle and the recognized road surface marking at a pre-set time interval, and compare the calculated variation with a preset value to generate lane change information. The system also includes a driving lane estimating unit configured to estimate the driving lane of the vehicle on the basis of information of the lane in which the vehicle is driving and the lane change information. |
US09604572B2 |
Method for maintaining a warning signal in a motor vehicle on the basis of the presence of a target object in a warning region, in particular a blind spot region, corresponding driver assistance system, and motor vehicle
A method for the output of a warning signal for warning the driver of a motor vehicle about the presence of a vehicle-external target object in a warning region, which is prescribed in relation to the motor vehicle, by means of a driver assistance system of the motor vehicle, in which a radar sensor is used to transmit electromagnetic radar signals into a sensing region of the radar sensor in each of successive measurement cycles of the radar sensor and to receive received signals, the received signals are used for detection of the target object by means of the radar sensor and for tracking said target object in the sensing region over the measurement cycles, and, if the target object enters the prescribed warning region, the warning signal is output by means of an output device. |
US09604569B1 |
Window lighting system of a vehicle
A vehicle lighting system is provided herein and includes a window of a vehicle. A light-producing assembly is coupled to the window and includes a photoluminescent member configured to luminesce in response to excitation light provided by a light source and a decorative member for concealing the photoluminescent member, wherein the photoluminescent member luminesces to accentuate an indicium defined by the decorative member. |
US09604568B1 |
Vehicle light system
A vehicle having a trim housing disposed on the vehicle and partially concealing a latch is provided herein. A light projector is disposed within the trim housing and is configured to illuminate a lighted image pattern on a surface of the vehicle. The image pattern is configured to provide assistance in locating a switch. |
US09604567B1 |
Luminescent trailer hitch plug
A trailer hitch plug is provided herein. A base member is configured to luminesce in response to excitation light provided by a light source. An electrical connector is provided at the base member. A cover is removably coupled to the electrical connector and configured to luminesce in response to excitation light provided by the light source. |
US09604566B1 |
Lamp structure
A lamp structure is provided in which a roof rack fixed on top of a car has an engaging slot for locking with a detent portion formed on the bottom of a positioning unit. A connecting portion extending on the detent portion has a fitting indentation with a positioning member penetrating therethrough, one end of the positioning member having a snap-fit portion provided on one end and a positioning pulling lever pivotally provided on the other end. A warning lamp having a snap-fit groove for engaging with the snap-fit portion is combined with the connecting portion. Therefore, the warning lamp has higher assembly position so that light emitted from the warning light is clearly visible by rear drivers from a longer distance and hence has better eye-catching and warning effect, and better driving safety can be achieved. |
US09604565B2 |
Wirelessly controlled heads-up display having solar charging and charge level indication
A heads up display apparatus for a vehicle, comprising a wireless transceiver configured to connect and communicate with a device providing information for display, an energy storage device configured to provide energy to the display apparatus, a processor configured receive information from the transceiver and configure the information for display, and a display configured to output the information. |
US09604562B2 |
Heating and cooling cup holder
A heating and cooling cup holder includes: a holder body to store a beverage container, a shape enclosing the beverage container, and a blowing hole to which wind is introduced; a heat exchanger having a front coupled to an outer side of the holder body to cover the blowing hole and an inlet to thereby allow the wind introduced into the inlet to be heat-exchanged and then discharged into the holder body through the blowing hole; a Peltier element having a front coupled to a rear surface of the heat exchanger and a heat pipe having a front of one end portion coupled to a rear surface of the Peltier element and the other end portion extended to a side direction; and a radiating module coupled to one end portion of the heat pipe and a radiating fan arranged at a rear of the radiating module. |
US09604559B2 |
4-way lumbar support
Disclosed herein is a 4-way lumbar support capable of automatically adjusting a vertical curved position and an amount of curvature of a lumbar plate, while securely supporting the lumbar plate even when a large load, such as the rear-end collision of a vehicle, is applied to the lumbar plate. In addition, the 4-way lumbar support can adjust an amount of forward curvature of the lumbar plate using a pusher including a pair of hinge members, thereby enabling the amount of forward curvature of the lumbar plate to be adjusted across a wider range without increasing the thickness of a seat back in the forward and backward directions thereof. |
US09604556B2 |
Vehicular seat
A vehicular seat includes: a seat cushion that is disposed offset with respect to a vehicle width direction center of a vehicle; an airbag that is provided in the seat cushion and which, upon receiving a supply of gas, is expanded and deployed in such a way as to suppress a seated occupant from moving toward the front of the vehicle; and gas supplying device which, when actuated at the time of a frontal impact of the vehicle, supplies gas to the airbag in such a way that a vehicle width direction outer side section of the airbag with respect to a vehicle width direction center of the seat cushion is expanded and deployed before an inner side section. |
US09604551B2 |
Apparatus for locking seat-rail in vehicle and manufacturing method thereof
The present disclosure provides an apparatus for locking a vehicle seat-rail that improves the assembly convenience of a lever assembly and enhances space utilization of the seat-rail upper portion, and an assembling method. The apparatus includes a fixing bracket that is fixed to an outer surface of a moving rail; and an unlock lever that is rotatably coupled to the fixing bracket at an interruption. In particular, a rotation stopper is formed to protrude from a side surface of the unlock lever, and a fixing stopper is provided in a rotation path of the rotation stopper to regulate the excessive rotation of the unlock lever in one direction at the time of rotation of the unlock lever. |
US09604548B2 |
Driving force controller for electric vehicle
The driving force controller for an electric vehicle that controls driving force of a motor in the drive system of an electric vehicle includes: a target driving force setting unit for setting the target driving force based on a request from a driver; a dividing unit for computing a first motor torque command value by dividing the target driving force by a reduction ratio; a target acceleration computing unit for computing target acceleration by dividing the target driving force by inertia of the drive system; an actual acceleration computing unit for computing actual acceleration by differentiating actual rotational speed of the motor; a correction amount computing unit for computing a correction amount for reducing deviation between the target acceleration and the actual acceleration; and a command value computing unit for computing a second motor torque command value by adding the correction amount to the first motor torque command value. |
US09604547B2 |
Vehicle for a magnetic levitation track
The present invention relates to a vehicle for a magnetic levitation track having a coach body (1) and a propulsion and supporting device (4) as well as at least one levitation frame (2) fastened on the coach body (1) and the propulsion and supporting device (4). The levitation frame (2) can be deflected transversely to the longitudinal axis of the propulsion and supporting device (4) and a spring suspension system (12, 14, 20, 21) is arranged between the levitation frame (2) and propulsion and supporting device (4). The levitation frame (2) has a traverse (13) and a carrier (17) which are connected to each other in an articulated fashion. |
US09604545B2 |
Carrier communication method and system based on charging-discharging of electric vehicle and carrier device
A carrier communication method and system based on charging-discharging of an electric vehicle and a carrier device are disclosed. The carrier communication method comprises: determining whether a carrier signal from a peripheral apparatus is detected at an interface harness and if yes, determining whether the carrier signal is correct, when the electric vehicle is powered on to start; when the electric vehicle detects the carrier signal and the carrier signal is correct, receiving the carrier signal via the interface harness; and performing a coupling and filtering on the carrier signal to convert the carrier signal into a standard carrier signal and demodulating the standard carrier signal into a digital signal to obtain information about the peripheral apparatus. |
US09604541B1 |
System and method for customizing a vehicle operating environment
A method and system are presented for configuring a vehicle operating environment. An initial VOE configuration file and a VOE components file are provided to a VOE configuring application. A user employs the application to modify the VOE configuration file. The modified VOE configuration file is provided to a vehicle, where the vehicle uses the modified VOE configuration file to configure an operating environment of the vehicle. |
US09604540B2 |
In-vehicle display apparatus
A display unit incorporated in the housing surface of an instrument panel changes its display variously together with other display devices of the instrument panel such as a liquid crystal display, and displays information such as driving information, danger notification information and entertainment information in coordination. |
US09604538B2 |
Vehicle provided with an engine at the rear and having an improved clutch system
A vehicle including an engine at a rear, and a clutch system including a hydraulic conduit passing below the vehicle and connecting a master cylinder placed at the front of the vehicle and a slave cylinder located at the rear thereof. The hydraulic conduit is positioned in a vicinity of a pre-existing heat source in the vehicle, to be heated by the heat source. |
US09604535B2 |
Vehicle
A vehicle (3) equipped with gas tanks (30a, 30b) has a common channel (34c) and branch channels (34a, 34b) that branch from the common channel (34c) to the gas tanks (30a, 30b), as a filling passageway (34) through which gas is supplied from an external gas station (2) to the gas tanks (30a, 30b). The gas tank (30a) is better in heat dissipation characteristic than the gas tank (30b). Only the branch channel (34a) that corresponds to the gas tank (30a) is provided with a shutoff valve (40) or a flow regulation valve (46) that is capable of restricting the amount of gas supplied to the gas tank (30a). |
US09604533B2 |
Vehicle and control method for vehicle
A vehicle includes an electric power storage device, motors, a grille shutter and at least one ECU. The ECU is configured to: (i) control the motors and the grille shutter, (ii) calculate the SOC of an electric power storage device, and (iii) execute opening control of the grille shutter such that a first amount of the air exceeds a second amount of the air. The first amount of the air is an amount of the air introduced into the vehicle from the outside of the vehicle when the SOC exceeds a predetermined value. The second amount of the air is an amount of the air introduced into the vehicle from the outside of the vehicle when the SOC does not exceed the predetermined value. |
US09604530B2 |
Drive system for hybrid vehicle
A drive system for a hybrid vehicle, the drive system includes an engine (1), a rotary machine (MG1), a differential unit (20), and a transmission unit (10). The rotary machine (MG1) is arranged coaxially with the engine (1). The differential unit (20) connects the engine (1) and the rotary machine (MG1) to a drive wheel side. The differential unit (20) is arranged coaxially with the engine (1) and the rotary machine (MG1). The differential unit (20) is arranged between the engine (1) and the rotary machine (MG2). The transmission unit (10) changes rotation of the engine in speed and transmits the rotation to the differential unit (20). The transmission unit (10) is arranged coaxially with the engine (1), the rotary machine (MG1) and the differential unit (20). The rotary machine (MG1) and the differential unit (20) are arranged between the transmission unit (10) and the engine (1). |
US09604526B2 |
Method for providing improved driveability for a vehicle
A method for controlling torque delivery in a vehicle powertrain using an enhanced limited operating strategy. The strategy is implemented when a powertrain controller fails to respond properly to a driver command for traction wheel torque whereby a modified wheel torque at vehicle traction wheels under driver control is made available. |
US09604524B1 |
Tonneau cover system with tension adjustment
A pair of tension adjustment blocks can include one or more positioning members receivable in the tension adjustment block mounting aperture to define a selected one of a plurality of distances from the aperture to a corresponding end of the tension adjustment block. When the tension adjustment blocks are selectively arranged in one of a plurality of orientations with one of the positioning members inserted into the tension adjustment block mounting aperture of each of the side rails to define a selected distance, the corresponding end of each tension adjustment block retains a header at a selected fore/aft position related to the selected distance that is different from the other adjustment tension adjustment block orientations and related distances. |
US09604523B2 |
System having a control unit
Systems, kits and methods for transferring heat with a portion of a mammal are provided. Aspects of the subject systems include a negative pressure device configured to apply negative pressure to a portion of a mammal, and a temperature modulation device configured to contact the portion of the mammal under negative pressure in a manner sufficient to transfer heat with the contacted portion of the mammal, e.g., either remove heat or introduce heat into the contacted portion of the mammal. The disclosed systems and methods find use in a variety of different applications, including both therapeutic and non-therapeutic applications. |
US09604522B2 |
Method for the remote activation of a function of a motor vehicle and computer program product
A method remotely activates an air-conditioning function of a motor vehicle by a mobile communication device. This involves transmitting an activation signal by a mobile communication device to a receiver device of the motor vehicle, receiving the activation signal by the receiver device of the motor vehicle, determining a current location by a location-determining device of the motor vehicle, transferring information about the determined location from the motor vehicle to the mobile communication device, and activating the air-conditioning function of the motor vehicle if the receiver device has received a confirmation signal transmitted by the mobile communication device. |
US09604520B2 |
Pneumatic spring arrangement or pneumatic spring damper with integrated valve control
An air spring assembly or air spring damper with an integrated valve control for controlling a level position of a vehicle or of a driver's cab includes a rolling tube, a lid and an air spring bellows which together delimit a pressure chamber with compressed air. A control valve includes an actuation device for feeding compressed air into the pressure chamber or for discharging compressed air from the pressure chamber. A compression spring device has a first end operatively connected to the rolling piston or the lid and a second end operatively connected to the actuation device. The compression spring device is configured with at least two parts including a central spring facing towards the rolling piston or the lid and a control valve biasing spring facing towards the control valve. The central spring is biased to a greater extent than the control valve biasing spring. |
US09604515B2 |
Spring for a motor vehicle
A spring made of a fiber composite includes a metal thread which is connected to the spring and has an electrical resistance which changes in dependence on a deformation of the spring. The metal thread can be integrated inside the spring or may also be arranged on an outer side of the spring. |
US09604510B2 |
Method for setting multiple TPMS sensors
A TPMS (tire pressure monitoring system) sensor setting method is disclosed to use a setting tool for selecting the ID codes of multiple TPMS sensors and burning a communication protocol into the multiple selected TPMS sensors at a time, significantly shortening the operation time. |
US09604509B2 |
Vehicle axle assembly comprising integrated pressure medium line for filling tires
A vehicle axle assembly includes a hub, which is mounted on a cylindrical axle body so that it can rotate about a central longitudinal axis, and an axially inner and an axially outer shaft sealing ring for indirect or direct sealing between the axle body and the hub. In order to enable an autonomous feed of pressure medium into a vehicle tire, the vehicle axle assembly includes an annular chamber that is formed between the two shaft sealing rings, the axle body and the hub, a first pressure medium line that extends through the axle body or one of the two shaft sealing rings and opens out into the annular chamber, and a second pressure medium line that extends out of the annular chamber through the hub and is designed to be connected to a wheel that is secured on the hub. |
US09604508B2 |
Method for communicating data between an NFC-enabled device on a vehicle and a driver indentification device
A method for communicating data between a vehicle and a mobile computing device includes locating at least one NFC-enabled device on the vehicle. Vehicle user data is wirelessly transferred between the NFC-enabled device and the mobile computing device. Using the vehicle user data, the NFC-enabled device on the vehicle and the mobile computing device are paired. |
US09604498B2 |
Wheel assembly
A wheel for a pneumatic tire has a rim with one monolithic bead seat and a removable beat seat. The removable bead seat has two halves that embrace the rim and engage a groove to retain the tire. The removable bead seat may have a second lip either monolithically formed or as a part of a separate retainer that bolts to the bead seat. The wheel may be made from aluminum alloy. |
US09604497B2 |
Wheel assembly for an irrigation system
A wheel assembly for traversing a path along a ground surface having a layer of soil, the wheel assembly comprising a central support and an airless flexible covering mounted on the central support and having a plurality of rigid sections and a plurality of flexible sections. The outwardly protruding spokes urge the rigid sections into the layer of soil when the rigid sections contact the ground surface. The flexible sections flex inwardly when the flexible sections contact the ground surface so that the rigid sections and the flexible sections cooperatively form a corrugated pattern in the ground surface without urging the soil to side margins of the airless flexible covering, the corrugated pattern having a plurality of valleys formed by the rigid sections and a plurality of peaks formed by the flexible sections. |
US09604488B2 |
Printing system with creasing control, control method thereof, control apparatus, and non-transitory computer-readable storage medium
A printing system comprises: a printing unit configured to print an image on a sheet; and a control unit configured to control to perform creasing at a first pressure at a portion, corresponding to an edge of a spine cover, of the sheet on which the printing unit has printed the image, and perform creasing at a second pressure different from the first pressure at a portion of the sheet that corresponds to a hinge. |
US09604482B2 |
Adjustment mechanism, image forming apparatus including adjustment mechanism, and adjustment method using adjustment mechanism
An adjustment mechanism (130) adjusts a position of a target object (110) attached to an attachment base (120). The adjustment mechanism (130) includes a first cam (131) and a second cam (132). The first cam (131) is attached to a shaft portion (123) on the attachment base (120). The second cam (132) houses the first cam (131) and supports the target object (110). The first cam (131) displaces the target object (110) via the second cam (132) by rotating about the shaft section (123) as a rotational axis. The second cam (132) displaces the target object (110) by rotating about the first cam (131) as a rotational axis. An amount of displacement of the target object (110) resulting from rotation of the first cam (131) differs from an amount of displacement of the target object (110) resulting from rotation of the second cam (132). |
US09604479B2 |
Image forming apparatus
An image forming system superposes a plurality of recording sheets on top of another by a predetermined number of sheets and discharges the recording sheets. The image forming system includes a recording sheet conveyor, a recording sheet superposition unit, and a controller. The recording sheet conveyor conveys the recording sheets. The recording sheet superposition unit superposes a preceding recording sheet and a succeeding recording sheet sent from the recording sheet conveyor. The controller controls the recording sheet superposition unit not to superpose the preceding recording sheet and the succeeding recording sheet when the controller refers to recording sheet information of the preceding recording sheet and determines that the preceding recording sheet is a recording sheet of a specified kind. |
US09604475B2 |
Media processing device with enhanced media and ribbon loading and unloading features
Provided herein is a media processing device including a printhead assembly, a frame, and a biasing element. The printhead assembly includes a printhead and a printhead bracket, where the printhead assembly extends in a longitudinal direction between a first end and a second end, and where the printhead bracket includes a biasing force receiving element. The frame may be configured to receive and support the printhead assembly, where the frame includes a first portion disposed adjacent to the first end of the printhead assembly, and a second frame portion is disposed adjacent to the second end of the printhead assembly. The biasing element may extend between the first frame portion and the second frame portion, where the biasing element may engage the biasing force receiving element of the printhead assembly. |
US09604473B2 |
Image recording device
A first feeder contacts a first surface of a first sheet held in a first tray and feeds the first sheet toward a recording unit. A second feeder contacts a first surface of a second sheet held in a second tray and feeds the second sheet toward the recording unit. An inner member is disposed above a standing plate. An outer member comprises an upstream portion opposing the standing plate, and a downstream portion opposing the inner member. The inner member guides the first surface of the first sheet and the first surface of the second sheet. The standing plate guides the first surface of the second sheet. The upstream portion of the outer member guides a second surface of the second sheet, and the downstream portion guides a second surface of the first sheet and the second surface of the second sheet. The standing plate moves relative to the outer member. |
US09604470B2 |
Sheet decurling device and ink-jet type image forming apparatus including this
A sheet decurling device includes a decurling conveyance part and a nip forming part. The decurling conveyance part includes a plurality of first rollers provided axially rotatably and a first belt wrapped around the first rollers. The nip forming part forms a nip part nipping and conveying a sheet with the first belt. The nip forming part includes a plurality of decurling rollers whose curvatures of outer circumferential surfaces are different from each other and a change-over mechanism. The change-over mechanism supports the plurality of de curling rollers axially rotatably and selectively changes over the decurling roller to be brought into pressure contact with the first belt. |
US09604469B2 |
Curl control assemblies
Examples disclosed herein relate to computer readable medium with instructions that when executed on a processor cause the processor to control a curl control assembly for use in a device having an output for media. |
US09604465B2 |
Ink-jet recording apparatus
A recording apparatus includes a recording head, a sub tank, an ink tank containing ink supplied to the sub tank, a detector that detects an amount of ink contained in the sub tank, a variable volume member provided between the recording head and the sub tank and having variable inner volume, and a controller that repeatedly performs first and second operations, thereby supplying ink from the ink tank to the sub tank. In the first operation, the member is caused to switch from a first state to a second state, while in the second operation, the member is caused to switch from the second state to the first state. |
US09604464B2 |
Inkjet recording apparatus and method therefor including ink detection and notification features
An inkjet recording apparatus includes an ink tank, a recording head, an ink sensor, a monitor, an operation panel, and a controller configured to control operation thereof. The controller receives a completion signal indicating completion of ink injection, and receives a first signal or a second signal from the ink sensor based on whether a predetermined amount of ink is sensed in the ink chamber. Based on the completion signal and receipt of the first signal, inquiry information is displayed on the monitor regarding whether ink injection into the ink chamber is completed. Based on the completion signal and receipt of the second signal, a notification is displayed on the monitor that is based on the ink sensor not sensing the predetermined amount of ink. |
US09604463B2 |
Cartridge case
A cartridge case includes a case body, a shaft portion, a first support portion, a second support portion, and a switching member. The shaft portion includes a shaft support portion and engages with an end portion of an elastic member. The shaft portion is configured to be moved by an energizing force of the elastic member. The switching member is configured to switch a position of the second support portion between an operating position and a released position. The operating position is a position where the second support portion and the first support portion hold the shaft support portion between the second support portion and the first support portion. The released position is a position where the second support portion has moved away from the shaft support portion. |
US09604462B2 |
Printing fluid restrictor plate for an ink jet print head assembly and method
A restrictor plate for an ink jet print head assembly includes a substantially flat body having fluid flow passageways extending through the body. The fluid flow passageways are elongated between a fluid receiving volume end and an opposite fluid ejection volume end. The receiving volume end is fluidly coupled with a chamber and the ejection volume end is fluidly coupled with an orifice of the assembly from which the fluid is ejected. The receiving volume end receives the ink from the chamber so that the ink flows through the passageways along a printing direction. The body is shaped around the one or more fluid flow passageways to form one or more bottlenecks in the one or more fluid flow passageways that increase a fluid flow resistance of the fluid along a direction in the one or more fluid flow passageways that is opposite of the printing direction. |
US09604461B2 |
Printing device
A printing device includes a head portion, a receptacle portion, an absorption member, a discharge outlet, and a plurality of extended wall portions. The head portion includes a nozzle face having a nozzle. The absorption member is supported by the receptacle portion, is provided to absorb the liquid, and has a through-hole. The through-hole extends through the absorption member between a first face and a second face in an orthogonal direction to the nozzle face. The first face is an opposite side to the second face. The second face faces the nozzle face in the orthogonal direction. The discharge outlet is provided in a bottom wall portion of the receptacle portion and is continuous with an outside of the receptacle portion. The bottom wall portion extends along the nozzle face. The extended wall portions project from the bottom wall portion to the nozzle face side and support the first face. |
US09604440B2 |
Manufacturing process for the production of flexible three-dimensional items
Manufacturing process for the production of flexible three-dimensional items which entails: cutting the pieces (4) which will form the outer material of the item to be produced, preparing a mould (1) and a counter mould (3) with smooth opposing surfaces onto which the cut pieces (4) which will form the outer material are placed, these cut pieces, alongside the mould and counter mould, delimiting a network of channels (6) through which a molten plastic material is injected. |
US09604437B2 |
Method for manufacturing structural body and manufacturing apparatus therefor
A method for manufacturing a structural body includes a lamination step of, while an in-process structural body is supported by a support member, laminating a plurality of times, a layer which is provided on a surface of a transfer member and which is to be formed into the structural body on the in-process structural body or at least a part of a surface formed of the in-process structural body and the support member, and in the lamination step, the support member is moved by changing the state thereof. |
US09604436B2 |
Thermoplastic polyurethane interlayer
A composition includes an isocyanate, a polyether diol, a branched short chain diol having a backbone including carbon atoms in a range of 1 to 9 and at least one branching group, and a cross-linker having a hydroxyl functionality in a range of 2.2 to 4. A films includes the composition and an interlayer includes the film. Transparencies including the interlayer and methods of making the same are further disclosed. |
US09604434B2 |
Window for display device and display device including the window
A window for a display device, the window including a polymeric substrate, a polymeric layer disposed on a side of the polymeric substrate, and a binder layer interposed between the polymeric substrate and the polymer layer, wherein the binder layer includes a binder and a blue colorant. |
US09604430B2 |
Thin film for waste packing cassettes
The present invention refers to a polymeric film comprising an odor barrier material and being able to pack malodorous waste. |
US09604428B2 |
Ventilated structural panels and method of construction with ventilated structural panels
A multi-plenum structural panel comprising a top sheet, a middle sheet, and a bottom sheet, each sheet being parallel to the other two. A first plurality of spacing structural elements, fixedly attaching the top sheet to the middle sheet, and a second plurality of spacing structural elements fixedly attaching the middle sheet to the bottom sheet, such that a yield strength of an assembled multi-plenum structural panel is greater than a sum of individual sheet yield strengths. An upper plenum is defined by a first spacing between the top and middle sheets. A lower plenum is defined by a second spacing between the middle and bottom sheets. The first plurality of spacing structural elements is formed such that a first plurality of spaced apart unobstructed pathways are created in the upper plenum for air to move in a first direction from at least one edge of the multi-plenum structural panel to at least one of an opposite and an adjacent edge of the multi-plenum structural panel in each plenum. The second plurality of spacing structural elements is formed such that a second plurality of spaced apart unobstructed pathways are created in the lower plenum for air to move in a second direction from at least one edge of the multi-plenum structural panel to at least one of an opposite and an adjacent edge of the multi-plenum structural panel in each plenum, where the first direction is orthogonal to the second direction. |
US09604427B2 |
Fiber/plastic sheet product cutting-folding machine
A fiber/plastic sheet product cutting-folding machine composed of a cutter, a rotary cutting wheel, one or more differential wheels, a first folding wheel and a second folding wheel is disclosed. The cutter and the rotary cutting wheel are adapted to cut off a fiber/plastic sheet product passing therebetween so that each cut piece of fiber/plastic sheet product has a straight cut edge. The differential wheel enables each two successive cut pieces of fiber/plastic sheet product to be partially overlapped, forming a stack of interfold fiber/plastic sheet product. Subject to the application of the fiber/plastic sheet product cutting-folding machine, each stack of interfold fiber/plastic sheet product is kept neat. |
US09604424B2 |
Method of manufacturing pneumatic tire
The present technology provides a method of manufacturing a pneumatic tire. The method of manufacturing a pneumatic tire uses a laminated sheet having a predetermined length and an inner liner layer formed from the laminated sheet through a step of cure-molding the tire with end portions of the laminated sheet lap-spliced. In the method, when at least the sheet made of thermoplastic resin or a thermoplastic resin composition obtained by blending the thermoplastic resin and the elastomer is cut into the predetermined length, the cutting is performed by using an edge tool having a non-sharp edge under a temperature condition not lower than 60° C. and not higher than a melting point of the thermoplastic resin. |
US09604421B2 |
Apparatus for manufacturing tyres for vehicle wheels
An apparatus for manufacturing tires for vehicle wheels includes devices designed to form a green tire, a vulcanization mold having holding walls defining a molding cavity, and devices for transferring the green tire into the molding cavity. The vulcanization mold includes a plurality of vent valves, at least one of which includes a duct and a closure member having a closing head that is axially movable relative to the duct. The closing head is movable between a closed position, at which the closing head forms a contact seat, and an open position, at which the closing head and inner wall confine a passage for connection with the molding cavity. |
US09604420B2 |
Tire puncture sealant
An object of the present invention is to provide a tire puncture sealant having excellent sealing performance and low-temperature properties. The tire puncture sealant of the present invention contains a natural rubber latex (A) and a vinyl versatate copolymer resin emulsion (B) as an emulsion of a vinyl versatate copolymer resin (b1) containing vinyl versatate as a monomer unit; the proportion of the vinyl versatate with respect to all monomer units constituting the vinyl versatate copolymer resin (b1) being from 30 to 70 mass %. |
US09604419B2 |
Oblong configuration for bonded patch
A patch for a structure has a rework area with an inconsistency formed therein. The patch comprises a patch body having at least two regions including a fail-safe region and a safe-life region encompassing the fail-safe region. The safe-life region has a mode I interlaminar fracture toughness that is less than the mode I interlaminar fracture toughness of the fail-safe region. |
US09604415B2 |
Method for producing FRP
A method for producing FRP in which a preform made of a reinforcing fiber base material is disposed in a cavity of a mold, a resin injection path and a suction path that sucks at least air are provided to the mold, and resin from the resin injection path is caused to flow in the direction toward the suction path in the cavity to be impregnated into the preform, wherein a high flow resistance region for partially making the resin flowing in the preform hardly flow is formed in the preform itself, and a flow front of the resin flowing in the direction toward the suction path through the high flow resistance region is controlled to settle within a permitted region that has been predetermined relative to a shape of a product to be molded. |
US09604413B2 |
Assembling and shaping laminate panel
A method of assembling and shaping a laminate panel. An intermediate member is mounted on a lay-up table and a lay-up is assembling by laying a series of plies onto the intermediate member on the lay-up table. The intermediate member and the lay-up are then removed from the lay-up table and placed them on a shaped surface. The lay-up is then forced against the shaped surface, via the intermediate member, in a manner that modifies the shape of the lay-up to form a shaped laminate panel. Finally the shaped laminate panel is removed from the intermediate member. The lay-up table can thus support the flexible intermediate member during assembly, and can be relatively flat to enable the lay-up to assembled by an automated process. |
US09604411B2 |
Multi-material three dimensional printer
A layer of a first powder is dispensed in a layer over a build plate. Binder is then selectively applied to hold portions of the layer of first powder together. Unbound first powder is then removed. A second powder is then dispensed in a layer over the build plate and portions of the bound first powder above the build plate. Binder is then selectively applied to hold portions of the second powder together. Unbound second powder is then removed. A third or more different powders can be similarly dispensed and bound to complete a multi-material layer. The process is then be repeated on a next subsequent layer. A curing radiation source can accelerate binding of powder together. Voids can be formed in portions of the layers by dispensing a fugitive material in portions of each multi-material layer. Mechanisms for implementing the printing process are also disclosed. |
US09604399B2 |
Injection molding flow control apparatus and method
An apparatus for controlling the rate of flow of fluid mold material from an injection molding machine to a mold cavity, the apparatus comprising: a manifold having a fluid delivery channel, an actuator interconnected to a valve pin having a tip end drivable between a first position, a second position upstream and a third position upstream of the second position, the actuator and the valve pin being translationally driven by a valve system adjustable between a start position, a plurality of intermediate drive rate positions and a high drive rate position, a pressure sensor and a controller, the pressure sensor sensing a metered pressure of a drive fluid, the controller instructing the valve system to drive valve pin continuously upstream and including instructions that instruct the valve system to move according to a predetermined profile of metered pressures from the start position to selected intermediate drive rate positions and subsequently to the high drive rate position. |
US09604395B2 |
Automatic opening and closing device for a mold assembly
An automatic opening and closing device for a mold assembly includes a base, a pivot seat, a first extensible unit, an upper mold mounting unit, two shafts, a second extensible unit, a left arm and a right arm. The first extensible unit can move the upper mold mounting unit downward to clamp or release the mold, and the second extensible unit is used to move the pivot seat between two positions. When the pivot seat is in a first position, the upper mold mounting unit can be lowered down to secure or release the mold by the first extensible unit, when in the second position, the upper mold mounting unit and the mold can be rotated an angle, to perform opening or closing of the mold assembly. |
US09604392B2 |
Cooling fixtures for molded components
A cooling fixture for molded components includes a support surface, at least two brackets coupled to the support surface, and at least one roller having a central axis. The roller is coupled between the brackets for rotating about its central axis and is positioned for contacting a portion of a molded component and rotating about its central axis as necessary to align the molded component and substantially inhibit gouging of the molded component when the molded component is placed in the cooling fixture for cooling. Additional cooling fixtures and related methods are also disclosed. |
US09604383B1 |
Scissors attachment apparatus for a reciprocating tool
A scissors attachment can also be attached to the reciprocating tool for cutting one or more sheets of material. The scissors attachment includes an extension bar and first and second blades pivotally attached. A tool chuck coupling connects one of the blades to the reciprocating tool chuck of the reciprocating tool. A bar slot can be integrally defined on the tool or defined on the neck mount assembly for receiving and securing in place the extension bar. A method of stabilizing a cutting instrument is also provided. Additionally, a method of cutting material is provided. |
US09604382B2 |
Film cutter assembly
The present invention relates to a film cutter assembly in which a blade housing slides bilaterally along a pair of rails. The blade housing houses a blade. An elongated rail base is coupled or integral with a pair of rails. The rails are formed of a material which provides an attractive or adhesion property to attract the film to the rail and maintain the film in flat position before and after cutting. A double-side adhesive tape can be applied to a surface of the elongated rail base which is adapted for attaching the elongated rail base to a carton of film. |
US09604381B2 |
High speed small pack wrapper
A system for forming and wrapping a plurality of stacks of sheet like product is provided. The system includes a separator apparatus for converting a stream of spaced apart sets of stacks into a repeating stepped configuration. The system includes a mechanism for merging the stepped configuration of stacks into a single file stream of stacks. The system includes a cutoff apparatus for cutting a plastic sleeve in which the stacks are wrapped. The system includes a turner apparatus for changing the direction of travel of individual units comprising of a stack of product within a length of the sleeve 90 degrees while maintaining the orientation of the units. |
US09604378B2 |
Movable blade release mechanism for a cutting tool
A cutting tool includes a fixed blade having a cutting surface and a movable blade having a cutting surface. The movable blade is rotatable between a receiving position in which the cutting surfaces are spaced and a cutting position in which an object disposed between the fixed and movable blades is cut by the cutting surfaces. A return spring member is connected to the movable blade. The spring member stores energy when the movable blade is rotated from the receiving position to the cutting position. The spring member returns the movable blade to the receiving position when the stored energy is released. |
US09604375B2 |
Razor with blade heating system
A blade cartridge for a shaving razor contains a series of parallel blades and at least two contact segments as part of an electric circuit connected to the blades at spaced intervals to provide an electric current flow through the blades in a manner that provides more efficient heat distribution across the length of the blades. A radiator effect is created wherein heat produced by the contact segments passes between the blades towards the cutting edge of the blades. The combination of the heat produced by the electric current flow through the conductive blades and the heat produced by the contact segments provides a dual heat process that makes it easier to adjust and control the temperature to a desired stable heat temperature. A thin conductive film may be fitted to be in contact with the ends of the blades to insure conductivity throughout the entire length of each blade. |
US09604374B2 |
Method of making a lubrication box for a wet shaving implement
According to one aspect of the present invention, a lubrication box includes a first portion, a shaving aid material, and a second portion. The first portion of the lubrication box has a skin-engaging surface and at least one sidewall that, together, form a cavity. The skin-engaging surface includes at least two holes therethrough. The shaving aid material, which is optionally distributed in the cavity in a series of layers, is ultrasonically compressed into the cavity such that it at least partially fills at least one of the holes in the skin-engaging surface and at least a portion of the cavity. The second portion of the lubrication box is attached to the first portion such that the cavity is substantially closed. A gap exists between in the cavity between the shaving aid and the second portion of the lubrication box to permit the shaving aid material to expand during normal use. |
US09604373B2 |
Shaver
Provided is a shaver including a cartridge and a handle body. The cartridge includes a cartridge body formed in a rectangular frame shape; a plurality of blades installed in the cartridge body in the side-to-side direction of the cartridge body, each of the blades having a front portion bent downward; pair of side fixation slots formed on left and right frames of the cartridge body, respectively, so as to fix the left and right ends of each blade; a supporter connecting upper and lower frames of the cartridge body; and an inside fixation slot formed on the supporter so as to fix a portion of each blade. The handle body is coupled to the cartridge body. |
US09604371B2 |
Interlocking knives
Interlocking knives are provided. The interlocking knives include at least a first knife and a second knife. The first knife includes a blade and a handle. At least one slot may be formed through the blade of the first knife. The second knife also includes a blade and a handle. The second knife includes at least one slot. The at least one slot of the second knife interlocks with the at least one slot on the first knife. A swivel plate may be pivotally connected to the first knife. The swivel plate is operable to pivot towards the second knife into a locked position, securing the second knife to the first knife. |
US09604370B2 |
Link unit, arm module, and surgical apparatus including the same
A surgical apparatus having sufficient rigidity in a fixed mode and being freely operable in a steering mode includes one or more arm modules having at least one degree of freedom, each arm module including at least one steering cable to steer the arm module and a plurality of link units to form the at least one arm module, each link unit including a head disposed at an upper portion thereof and having a hemispherical shape, a seat formed at a lower portion thereof, and a sliding ball arranged at the seat, wherein the link units are arranged such that the head of one of the link units is seated on the seat of the other of the link units, and the head of one of the link units and the seat of the other of the link units are slid with respect to each other by the sliding ball. |
US09604369B2 |
Exoskeleton and method of increasing the flexibility of an exoskeleton hip joint
An exoskeleton comprises a torso brace, configured to be coupled to a torso of a user, and a leg support, configured to be coupled to a leg of the user. A plurality of links couples the torso brace to the leg support. The plurality of links includes a first link, coupled to the torso brace at a first pivot point, and a second link, coupled to the leg support at a second pivot point. The first link is coupled to the second link through a third pivot point located between the first and second pivot points. The first pivot point enables adduction of the leg support, and the third pivot point enables abduction of the leg support. |
US09604367B2 |
Area vacuum gripper
A surface area vacuum gripper having a housing with suction openings for sucking a workpiece to be gripped, at least one cover plate that seals the end face of the housing, an insertion element that can be inserted into the housing, wherein the insertion element can be fixed at the cover plate and comprises at least one opening which is flow-connected with the suction openings in the housing, the cover plate comprising a compressed air inlet. The insertion element comprises a functional device for controlling a flow through the opening of the insert. |
US09604363B2 |
Object pickup device and method for picking up object
A pickup device for picking up a target object from a plurality of objects randomly piled up in a container, and for placing the target object in a predetermined posture to a target location is provided. The device includes an approximate position obtaining part for obtaining information on an approximate position of the target object, based on information on a height distribution of the objects in the container, which is obtained by a first visual sensor. The device also includes a placement operation controlling part for controlling a robot so as to bring the target object into a predetermined position and posture relative to the target location, based on information on a position and posture of the target object relative to a robot, which is obtained by a second visual sensor. |
US09604359B1 |
Apparatus and methods for training path navigation by robots
An apparatus and methods for training and/or operating a robotic device to follow a trajectory. A robotic vehicle may utilize a camera and stores the sequence of images of a visual scene seen when following a trajectory during training in an ordered buffer. Motor commands associated with a given image may be stored. During autonomous operation, an acquired image may be compared with one or more images from the training buffer in order to determine the most likely match. An evaluation may be performed in order to determine if the image may correspond to a shifted (e.g., left/right) version of a stored image as previously observed. If the new image is shifted left, right turn command may be issued. If the new image is shifted right then left turn command may be issued. |
US09604353B1 |
Nail removal tool
A nail removal tool in the form of an adapter for attachment to the drive socket of a rotary driver such as a rotary pneumatic impact driver. The adapter includes a drive shaft engagable with the chuck of the pneumatic driver, a cylindrical bit with a slot for receiving the body of a nail and a ramp for engaging under the head and lifting it to dislodge the nail from its embedded location. Slop between the drive blade and the slot in the cylindrical bit serves as a flexible connection to provide proper presentation of cylindrical bit allowing wedging of the adapter beneath the head of a nail which is reluctant to be removed. |
US09604351B1 |
Oil filter removal and drain system and method
An oil filter removal and drain system including an oil-filter-removal assembly and a drain-attachment assembly in functional combination. The oil-filter-removal assembly includes a top-frame, a bottom-frame, a geared-socket-hub, a filter-socket, a plurality of geared-clamp-jaws, a filter-gasket, and a toggle-clamp in functional and structural combination. The drain-attachment assembly includes a drain-attachment-body, a drain-toggle-clamp, a drain-nipple, and a filter-cutter. The drain-attachment assembly is removably affixable to the oil-filter-removal assembly via the plurality keyhole-stud-receivers of the drain-attachment assembly accepting and retaining the plurality of keyhole-studs of the oil-filter-removal assembly. An oil-filter-removal assembly may be used on many different types of fluid filters (e.g., hydraulic fluid, diesel fuel, engine oil, etc.). |
US09604348B2 |
Tool for catching IC package
A tool for catching an IC package comprises a main body, a plurality of operation arms and a plurality of clamping arms. The main body has a base and a plurality of lateral portions rotating relative to the base. The operation arms each extends upwardly from a top portion of a corresponding lateral portion. The clamping arms each extends downwardly from a lateral portion and is formed with a clasping portion at a free end thereof, the clasping portion has a latching slot. The operation arms bring the lateral portions to rotate inwardly and open the clamping arms. |
US09604343B2 |
Hydro-filtration unit with sanding heads
A motor, a reservoir, a recovery basket, an internal hose, an external hose, a power switch, baffle with injection nozzles and floats, a sanding head, an extended sanding head, and a corner sanding head comprises a hydro-filtration unit with a sanding heads for drywall work. The sanding heads may be used to sand drywall and simultaneously draw the dust out of the air as it is created through the sanding process. The hydro-filtration prevents dust from being released into the air. Within the reservoir, the internal hose connects at one end to the motor and at the other to the floating dust injector unit and the injection nozzles. The external hose connects the sanding heads to the motor. |
US09604341B2 |
Drive System for orbital grinder
A drive unit for imparting rotation to a drum assembly of a floor grinder. The drive unit includes a rotatable pulley positioned adjacent to and in contact with a rotatable drive surface of a driven pulley of the drum assembly and a drive surface of the drum assembly. The rotatable drive surface of the driven pulley is configured to impart rotation to the rotatable drive pulley during rotation of the rotatable drive surface, and the rotatable drive pulley is configured to impart rotation thereof to the drum assembly. |
US09604340B2 |
Carrier head having abrasive structure on retainer ring
A carrier head includes a housing configured to enclose a wafer and a retainer ring attached to the housing. The retainer ring includes a body and an abrasive structure. The body includes an inner periphery configured to surround the wafer, an outer periphery, and a surface connecting the inner periphery and the outer periphery. The abrasive structure is attached to the surface of the body. |
US09604339B2 |
Vacuum-grooved membrane wafer polishing workholder
Hard-material, flat-surfaced workpieces such as semiconductor wafers or sapphire disks are attached with vacuum to the flexible elastomeric membrane of a rotatable wafer carrier that allows one surface of the workpiece to be in conformal abrading contact with a moving flat-surfaced abrasive. The elastomeric membrane external wafer attachment surface has a pattern of recessed vacuum grooves where vacuum supplied to the grooves firmly attach the rigid-material silicon wafer in flat-surfaced contact with the membrane. The attached wafer seals the vacuum grooves. A flexible thin metal annular membrane support disk is attached to the membrane within an abrading-pressure chamber where attached drive pins engage matching holes in the wafer carrier provide rotational torque to the wafer and restrain it laterally against abrading forces. Wafer polishing pressure is applied uniformly over the wafer surface. The rotating wafer peripheral edge does not contact a rigid retaining ring during a wafer polishing procedure. |
US09604337B2 |
Polishing method
A method of polishing a substrate is disclosed. The method includes irradiating the substrate with light; measuring intensity of the reflected light; producing spectral waveform representing relationship between relative reflectance and wavelength of the light; performing a Fourier transform process on the spectral waveform to determine a thickness of the film and a corresponding strength of frequency component; determining whether the determined thickness of the film is reliable or not by comparing the strength of frequency component with a threshold value; calculating a defective data rate representing a proportion of the number of unreliable measured values to the total number of measured values; and changing the threshold value based on the defective data rate. |
US09604336B2 |
Belt transmission device and grinding apparatus
The present disclosure provides a belt transmission device and a grinding apparatus. The device comprises: a grinding stand; rotation wheels mounted on the grinding stand, including a driver wheel and driven wheels; a grinding belt supported by rotation wheels; a first sensor fixedly provided on the grinding stand and configured to detect a rotation speed of any one of the driven wheels; and a controller configured to control a rotation speed of the driver wheel and connected with a driving motor of the driver wheel, wherein the controller is further connected with the first sensor, receives rotation speed signals of the one driven wheel detected by the first sensor, calculates difference between the rotation speeds of the driver wheel and the one driven wheel, and compares the difference with a predetermined difference range in the controller; and when the difference is beyond the predetermined difference range, an alarm is provided. |
US09604334B2 |
Positive feed tool with a slip clutch and a method, to prevent jamming
Positive feed tools and methods of use that include a spindle with a distal end configured to receive a tool bit. The spindle is movable in a forward direction for the tool bit to act on a workpiece, and a retract direction to move the tool bit away from the workpiece. The spindle is configured to retract to a home position at which an air motor that drives the spindle is shut off. The feed tool includes a clutch to prevent jamming of the spindle at the home position in the event the air motor is not shut off at the proper time. |
US09604331B2 |
Processing apparatus
A replacement device of a processing apparatus includes a gripping device having a single first support member positionally fixed, a first gripping portion provided on the first support member to grip a holder not to rotate in a releasing direction when the processing member is removed from the holder, and a second gripping portion provided on the first support member apart from the first gripping portion to grip the holder not to rotate in a restricting direction when the processing member is attached to the holder, and a holding device having a single movable second support member, plural first holding portions provided on the second support member to respectively accommodate the processing member removed from the holder, and plural second holding portions provided on the second support member apart from the first holding portions to respectively accommodate the processing member that is to be attached to the holder. |
US09604328B2 |
Heat sink structure and method of manufacturing same
A heat sink structure and a method of manufacturing same are disclosed. The heat sink structure includes a main body and a plurality of radiating fins. The main body has a plurality of coupling flutes circumferentially spaced along an outer surface thereof and longitudinally extended from a first end to a second thereof. The radiating fins respectively have a bent section integrally located between a first and a second heat radiating section. To quickly assemble the radiating fins to the main body, the radiating fins are disposed in a forming mold, and the main body is mechanically driven into the forming mold at a high speed, so that the bent sections of the radiating fins are longitudinally forced into the coupling flutes from the first to the second end of the main body to thereby tightly connect the radiating fins to the main body. |
US09604325B2 |
Canal hearing devices and batteries for use with same
Hearing devices configured to fit within the bony portion of the ear canal and batteries that may be used with same. |
US09604316B2 |
Tin-based solder composition with low void characteristic
A tin-based solder melt or aqueous tin plating bath composition comprising a source of tin and a stabilizing additive of chemical structure: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently selected from hydrogen atom, hydrocarbon groups R having at least one and up to twelve carbon atoms, groups OR′ wherein R′ is selected from hydrogen atom and hydrocarbon groups R, and halogen atoms, and wherein any two, three, or four of R1, R2, R3, R4, and R5 or any two, three, or four of R6, R7, R8, R9, and R10 are optionally interconnected to form a fused ring system; R11 and R12 are independently selected from hydrogen atom and hydrocarbon groups R; and r is either 0 or 1. Methods for coating and/or bonding metal substrates by use of the above-described solder compositions are also described. |
US09604315B2 |
Aluminum deoxidizing welding wire
Provided is a welding method and electrodes (wires) with aluminum as a primary deoxidizer and a basic flux system for joining a workpieces with weld metal of comparable strengths and enhanced toughness. For instance, provided is a welding wire, comprising an aluminum content configured to act as a primary deoxidizer, and an overall composition configured to produce a weld deposit comprising a basic slag over a weld bead, wherein the aluminum content is configured to kill the oxygen in the weld pool, and wherein the oxygen comprises oxygen provided by a shielding gas or produced by heating of welding filler materials. Further provided is a welding method comprising arc welding a workpiece using an electrode having aluminum as a primary deoxidizer under a gas shield to produce a bead of weld deposit and a basic slag over the weld bead. |
US09604314B2 |
Method for forming a mask pattern using a laser
A method of forming a pattern on a mask sheet using a laser beam includes determining a target scan line with respect to the mask sheet, which corresponds to a position of the pattern on a final mask sheet, determining a correction scan line with respect to the mask sheet, along which the laser beam is scanned to form the pattern of the final mask sheet, applying a counter force to the mask sheet, fixing the mask sheet onto a mask frame while the counter force is applied to the mask sheet, scanning the laser beam along the correction scan line, and releasing the counter force which is applied to the mask sheet. |
US09604311B2 |
Welded blank assembly and method
A welded blank assembly is formed by welding edge regions of separate sheet metal pieces together at a weld joint. One or more of the sheet metal pieces includes a coating material layer and a weld notch, where at least some of the coating material layer is removed from the edge region(s) prior to welding so that the weld joint is substantially free from constituents of the coating material layer. An additional material may be added to a weld pool during weld joint formation to influence the size, shape and/or composition of the resulting weld joint to help compensate for the presence of the weld notch. |
US09604309B2 |
Optical scanning device and laser machining device having pluralities of flat reflective surfaces corresponding to divided virtual arcs
An optical scanning device includes: a light projector configured to radiate light while causing the light to make angular movement at a constant speed; and a light reflector configured to reflect the light radiated from the light projector to guide the light to an intended irradiated point on a predetermined scanning line. The light reflector includes a plurality of reflecting portions and reflects, at least twice, the light radiated from the light projector to guide the light to the intended irradiated point. The reflecting portions each include a plurality of reflecting surfaces. A length of an optical path from the light projector to the irradiated point is substantially constant for all of irradiated points on the scanning line, and a scanning speed, on the scanning line, of the light radiated from the light projector is substantially constant. |
US09604306B2 |
Friction-stir welding tool, friction stir welding device, and method for manufacturing welding material
A friction-stir welding tool includes a front shoulder; a rear shoulder in contact with plate materials; and a probe penetrating the plate materials between the front and rear shoulders, the probe connecting the front shoulder and the rear shoulder to each other. The probe has a first screw part provided on at least one axial end section, and at least one of the front shoulder and the rear shoulder has a second screw part in threaded engagement with the first screw part, the threaded engagement changing so that the rear shoulder and the front shoulder approach each other along the axial direction as the front shoulder and the rear shoulder rotate relative to each other, and the threaded engagement with the first screw part linking at least one of the rear shoulder and the front shoulder with the probe. |
US09604300B2 |
Electrical connector with laser soldering and method for assembling the same
An electrical connector for electrically connecting a chip module and a circuit board, includes an insulating body, multiple terminals, and multiple solders. The insulating body includes multiple receiving holes running therethrough and multiple resisting portions. The terminals are respectively located in the receiving holes. One end of each terminal is provided with a soldering portion, the soldering portion has a soldering surface, and the soldering surface is perpendicular to a surface of the circuit board. Left and right sides of the solder urge the soldering surface and the resisting portion respectively, a lower side of the solder is soldered onto the circuit board by reflow soldering, and the solder is soldered to the soldering surface by laser. |
US09604297B2 |
Liquid dispensing system
The present invention relates to liquid dispensing system for a rotatable work tool (2), comprising a control valve (13), an inlet and outlet liquid guiding device (11, 15). The control valve (13) comprises a housing (18) with a rotatable drum part (19) arranged to rotate. The housing (18) comprises inlet and outlet tubes (21, 22) arranged to be connected to the liquid guiding devices (11, 15). The tubes (21, 11) have corresponding inlet and outlet openings (23) facing the drum part (19). The drum part (19) comprises a first seal (25) and a third seal (27), the seals (25, 27) running around the drum part (19). The third seal (27) has an extension (34) running partially along the first seal (25), such that a first and second volume (28, 29) are formed. Each opening (23, 24) is connected to one of the volumes, or both. At least one volume (29) enables fluid connection between the openings (23, 24) that is variable by means of the third seal (27) moving over one or more of the openings (23). Each such opening has a first maximum extent (30) in a first extension (35) and a second maximum extent (31) in a second extension (36), orthogonal to the first extension (35), the first extent (30) exceeding the second extent (31). |
US09604296B2 |
Working machine
A chainsaw as a working machine, which switches among stop, drive, and choke operations of an internal combustion engine, includes an operation lever that is turnable, a turning member turnably combined with the operation lever, and a torsion coil spring holding abutting of the operation lever and the turning member. The turning member is coupled to a choke operating member via a choke rod and is regulated in turning from drive position to stop position. When the operation lever is turned from drive position to choke position, the turning member also turns to move the choke rod, by which the choke operating member closes the choke valve. Meanwhile, the operation lever is turned from drive position to stop position, against the turning force of the torsion coil spring. |
US09604295B1 |
Coping saw
The present invention is a new and improved coping saw for performing a coping operation. The saw is operable in a first orientation for performing a first cut and in a second orientation for performing a coping second cut and comprises a handle having one or more power switches for activating and deactivating the drive system in both the first orientation and in the second orientation. |
US09604291B2 |
Ball-end milling cutter tool
A tool is disclosed that has an elongated tool body defining a longitudinal axis and includes a ball-end section having a positive taper angle relative to the longitudinal axis of the tool body, and a relief section that extends rearwardly from the ball-end section and has a negative taper angle relative to the positive taper angle of the ball-end section. |
US09604284B2 |
Portable drilling machine
A portable drilling machine wherein when a shorting failure occurs in a circuit part connected to a driving motor, this state is reliably detected and a false start of the motor is reliably prevented. A diving motor control circuit in the portable drilling machine includes a main control section; a triac and a relay which are connected to power supply terminals in series with the driving motor; peripheral circuits (a triac control circuit, a relay control circuit, a triac inspection and determination section, a bypass resistor, etc.) which are related to the triac and relay; and a current measurement section for measuring current flowing in the driving motor. |
US09604283B2 |
Alignment device, alignment element for such an alignment device, and an alignment method
The invention relates to an alignment device for precisely positioning a first functional element (103), particularly a retainer, on a second functional element (105), particularly a disc, these being detachably secured to each other. In the secured state (FZ), (a) at least one alignment element (115) is secured in a housing depression (117) of the first functional element (103) or the second functional element (105) by means of at least one securing element (131); (b) the alignment element (115) is connected to the first functional element (103) by means of at least one securing surface (119) and is in contact with a support surface (123) of said second functional element (105) by means of at least one contact surface (121); (c) a pre-tensioning device (125) acts between said contact surface (121) and support surface (123) and exerts a returning force, for returning to a starting position, onto the contact surface (121) and support surface (123) which are set one towards the other; and (d) the alignment element (115) is arranged laterally sunk into the housing depression (117), said contact surfaces (121) protruding above the lower side (133) of the first functional element (103). The invention is characterized in that in said secured state (FZ), the securing element (131) in question is arranged so as to be accessible from outside for the purpose of carrying out securing and/or justification processes, and in that the contact surface (121) is provided on a protruding body section (169) in the form of a block-shaped alignment element (115) engagement section. The invention also relates to an alignment element for such an alignment device, and to an alignment method. |
US09604274B2 |
Billet transfer line clean-out device and method
A processing line material clear out devices and methods are disclosed. The device is particularly useful for clearing metal billets from induction heating units, but may be used for many other processes having sequentially ordered materials traveling down a conveyor or other processing line. In one example of the invention, a reciprocating push rod rack is used to sequentially deposit and remove at least two push rods used to abut and clear the downstream billets. A push rod advance device is used to interlink independent, sequential push rods positioned on the billet track. On clearing of the billets, the push rods are retracted, removed from the billet track and stored on the push rod rack for ready use. |
US09604270B2 |
Method and apparatus for stretch-leveling metal strip
A metal strip is gripped by an upstream set of infeed tension rollers and, downstream therefrom in a strip-travel direction, by a downstream set of outfeed tension rollers. These tension rollers are rotated so as to tension the strip between the upstream and downstream sets and move the strip downstream in the strip-travel direction. Between the sets the strip first passes around individually supported relatively rotatable stretch rollers to increase a plastic stretch ratio of the strip, and then through a plurality of straightening rollers to reduce curvature and residual tension of the strip and also to increase the plastic stretch ratio of the strip. |
US09604263B2 |
System, tool and method for cleaning the interior of a freight container
A method for cleaning the interior of a freight container of ISO type having an access opening for receiving goods, wherein the method comprises: providing a cleaning tool comprising a framework, a robot movably connected to the framework and having a nozzle for supplying a cleaning medium including dry ice, and an actuating unit arranged to move the robot relative to the framework; gripping the framework of the tool with a truck designed for gripping and carrying freight containers of ISO type; driving the truck carrying the tool to the container to be cleaned; moving the robot into an interior of the container by means of the actuating unit; and moving the nozzle by means of the robot along a programmed cleaning path while cleaning the interior of the container by means of dry ice blasting. |
US09604261B2 |
Monitoring of optical fiber stripping
An apparatus for removing a coating from a lengthwise section of an optical fiber includes a heater at least partially defining an elongate heating region configured for receiving the lengthwise section of the optical fiber, wherein the heater is configured for heating the heating region to a temperature above a thermal decomposition temperature of the at least one coating; a sensor configured for providing a signal indicative of explosive removal of the at least one coating from the lengthwise section of the optical fiber; and at least one device operatively associated with the sensor and the heater for receiving and processing the at least one signal from the sensor, and deactivating the heater. The at least one device may be configured for determining how much time passes between occurrence of the heater being deactivated and the at least one coating being removed from the lengthwise section of the optical fiber. |
US09604258B2 |
Sortation systems and related methods
A conveying system for intended use in sorting articles and related methods of conveying and sorting articles are disclosed. In one embodiment, the system comprises a first conveyor extending in a first direction and a second conveyor extending in a second direction, with the directions intersecting. A transfer conveyor, such as a transpositor conveyor, may be provided for transferring articles from one of the first conveyors to one of the second conveyors. The system may be used to sort articles delivered from one or more storage locations for distribution, or may instead be used to sort articles for delivery to one or more storage locations. Related aspects and methods are also described. |
US09604256B2 |
Intelligent mail recovery tool
A system and method for providing intelligent mail recovery are provided. A cart for receiving a bucket containing mail items provide a camera and scale on a frame for detecting movement of mail items and determining destination as well as an associated weight of the mail item. An indicator is provided to an operator of the system as to the destination of the mail item. The mail item can then be sorted to the appropriate sort location. The system provides the ability to efficiently sort mail in addition to being portable within a sorting facility. |
US09604255B2 |
Method, apparatus and system for a transferable micromachined piezoelectric transducer array
Techniques and mechanisms to provide mechanical support for a micromachined piezoelectric transducer array. In an embodiment, a transducer array includes transducer elements each comprising a respective membrane portion and a respective supporting structure disposed on or around a periphery of that membrane portion. The transducer elements are initially formed on a sacrificial wafer, wherein supporting structures of the transducer elements facilitate subsequent removal of the sacrificial wafer and/or subsequent handling of the transducer elements. In another embodiment, a polymer layer is disposed on the transducer elements to provide for flexible support during such subsequent handling. |
US09604254B2 |
Phase track controller improvement to reduce loss of lock occurrence
A system and method for driving ultrasonic transducers and improvements to a phase track controller for reducing loss of lock occurrence is disclosed and described. |
US09604248B2 |
Removing a solvent from a drug-eluting coating
A coating device for coating a medical device with a drug-eluting material uses an in-process drying station between coats to improve a drug release profile. The drying station includes a heat nozzle configured for applying a uniform drying gas. |
US09604247B2 |
System and method to apply topping materials to print products
Disclosed are systems and methods, including a method that includes depositing a curable adhesive onto a first surface of a substrate in a pre-determined pattern, placing topping material onto the substrate with the deposited adhesive, and applying UV energy to the substrate including the deposited adhesive and the placed topping material to cause curing of the deposited adhesive. |
US09604246B2 |
Double-sided coating device
A double-sided coater 1 includes a first coater 5a coating a surface not contacting a guide roll 4b, and a second coater 5b coating another surface contacting the guide roll 4b. Each of the first and second coaters 5a and 5b includes a gravure kiss coater including a small-diameter gravure roll 10 and a coating liquid supplier 30. The guide roll 4b guides a substrate S from a vertical direction to a horizontal direction to allow the first coater 5a to coat the substrate S from a lateral point while the substrate S travels vertically, and to allow the second coater 5b to coat the substrate S from a lower point while the substrate S travels horizontally. |
US09604240B2 |
Mask assembly and method of fabricating the same
Provided are a mask assembly and a method of fabricating the same. The mask assembly includes a mask frame in which a frame opening is formed therein and insulation grooves are formed at both sides of a first direction with the frame opening therebetween. The mask has both ends disposed at the both sides and includes a plurality of pattern open parts configured by a plurality of pattern openings between the both ends. A movement member is provided in the insulation groove, to which the both ends of the mask are fixed, and which includes a movement block moving in the first direction and a second direction intersecting the first direction. |
US09604237B2 |
Pitch-based control for sprayers and sprayer operations
A computer-implemented method and a control system are described for controlling one or more operations of a sprayer vehicle with a tilt-detection mechanism, a tank, and a tank fill-volume sensor. The tilt-detection mechanism is utilized to determine a tilt indicator. A tilt value is determined based upon the tilt indicator. A tank fill-volume indicator is determined based upon information from the tank fill-volume sensor. A tilt-corrected fill-volume of the tank is determined based upon the tilt value and the tank fill-volume indicator. |
US09604226B2 |
Pulverizer mill protection system
A system for suppressing and inhibiting fires in coal pulverizer mills can include a fire suppression solution storage tank, a flow control cabinet, an equipment control/pumping enclosure, an air distribution system, and injection piping and nozzles installed at various positions in one or more pulverizer mills. A first set of nozzle assemblies in communication with the fire suppression solution can be positioned in the mill to disperse the suppression solution within the classifier zone of the mill. A second set of nozzle assemblies in communication with the suppression solution can be positioned within the mill to disperse the suppression solution within the grinding zone. A third set of nozzle assemblies can be positioned within the primary air duct of the mill. |
US09604225B2 |
Electrode arrangement for an electrodynamic fragmentation plant
The invention relates to an electrode arrangement for an electrodynamic fragmentation plant having a passage opening (1) for fragmentation material (3) and having several electrode pairs (4a, 5a; 4a, 5b; 4b, 5c; 4b, 5d; 4c, 5e; 4c, 5f; 4d, 5g; 4d, 5h) by means of which, by charging the electrodes (4a-4d, 5a-5h) thereof with high-voltage pulses, in each case high-voltage discharges can be generated within the passage opening (1), for fragmentation of the fragmentation material (3). The passage opening (1) is formed in such a way and the electrodes (4a-4d, 5a-5h) of the electrode pairs are arranged therein in such a way that for each electrode pair (4a, 5a; 4a, 5b; 4b, 5c; 4b, 5d; 4c, 5e; 4c, 5f; 4d, 5g; 4d, 5h) in the area of a shortest connecting line (L) between the electrodes of the respective electrode pair, a ball (K) can pass through the passage opening (1), the diameter of which is bigger than the length of this respective shortest connecting line (L).With such an electrode arrangement it is possible to carry out an electrodynamic fragmentation of fragmentation material in an economical manner with comparatively small high-voltage pulses. This also results in the possibility of expanding the realizable target value range of existing plants considerably in the direction of larger target values by retrofitting such plants with the electrode arrangement according to the invention. |
US09604224B2 |
System and method for processing objects having contaminating particles
A system and method for processing objects having contaminating particles includes the steps of shredding the objects in a shredding chamber to form a plurality of shredded fragments, wherein the shredding chamber is arranged to be substantially combustion resistant, and removing the contaminating particles from the plurality of shredded fragments. |
US09604220B2 |
Water and energy saving process for making whole grain and whole gluten-free grain flour
A water saving and energy saving process the continuous production of whole grain flour and whole gluten-free flour is provided. The process includes preconditioning whole-grain or seed with water and uses an energy efficient blanching treatment with saturated steam. The process also provides flour having a bimodal size mixture of material having improved viscosity. The whole grain and whole gluten-free flour can be used to prepare grain products and baked foods. |
US09604216B2 |
Sample preparation paper cartridge
A sample preparation cartridge is described having a lower portion having four integrally-formed leaf springs, and a raised lower base part which is slightly below the level of the leaf springs. An upper portion of the cartridge engages with the lower portion, via four paired pins and holes formed in the lower and upper portions. The upper portion includes three well-shaped openings formed in the central region of the upper portion. Between the upper and lower portions is placed a sheet of sample preparation paper, resting on the leaf springs, which raise the lower face of the paper away from the raised lower base part, leaving a small air gap between the base and the paper. The upper face of the paper is in contact with the well-shaped openings of the upper portion. The user loads a liquid sample into the openings, and the paper wicks the liquid sample away from the loading location, leaving cellular debris in the place of application. Applying pressure to the upper portion of the cartridge urges the paper into contact with the raised base portion, so providing a firm base which allows the user to remove sections of the paper, using for example a biopsy needle, for further processing. |
US09604213B2 |
System and method for processing and detecting nucleic acids
A system and method for processing and detecting nucleic acids from a set of biological samples, comprising: a capture plate and a capture plate module configured to facilitate binding of nucleic acids within the set of biological samples to magnetic beads; a molecular diagnostic module configured to receive nucleic acids bound to magnetic beads, isolate nucleic acids, and analyze nucleic acids, comprising a cartridge receiving module, a heating/cooling subsystem and a magnet configured to facilitate isolation of nucleic acids, a valve actuation subsystem configured to control fluid flow through a microfluidic cartridge for processing nucleic acids, and an optical subsystem for analysis of nucleic acids; a fluid handling system configured to deliver samples and reagents to components of the system to facilitate molecular diagnostic protocols; and an assay strip configured to combine nucleic acid samples with molecular diagnostic reagents for analysis of nucleic acids. |
US09604208B2 |
Test device for analyzing body fluids
A test instrument for analyzing body fluids such as blood or urine. The instrument includes a wound test tape which can be transported from a storage space into a waste space by advancing the tap. The test tape has a plurality of test sections to which body fluid can be applied at a receiving position and also includes a measuring unit for detecting a constituent of the body fluid on an active test section. In order to carry out auxiliary instrument functions, in addition to the test sections, the test tape has one or more functional sections which can be brought into a functional position by advancing the tape. |
US09604207B2 |
Pipette device
To provide an electric pipette in which the impact resistance against the dropping of the electric pipette is elevated, the external breakage of the device and the damage of operation performances are reduced, and the discharging performance of the device is maintained and ensured. An electric pipette 100 including a main casing 1, an operation switch 14, a hand grip 15, a display-operation section 9, a release switch 12 and a finger rest 16, in which at least one shock absorber 201 to 206 disposed on at least one apex of at least one line among a line LF, a line LB, a line LL, a line LR and a line LU, which are prepared by drawing lines between two or more projecting sites in each of a front surface 100F, a back surface 100B, a left side surface 100L, a right side surface 100R and an upper surface 100U. |
US09604206B2 |
Method for regenerating COS hydrolysis catalyst
A method for regenerating a carbonyl sulfide (COS) hydrolysis catalyst for hydrolyzing COS which is contained in a gas obtained by gasifying a carbon material, wherein a spent COS hydrolysis catalyst is immersed in an acid solution for a prescribed time thereby removing poisoning substances adhering to the surface of the COS hydrolysis catalyst; and thus regenerating the COS hydrolysis catalyst. |
US09604204B2 |
Process for the preparation of a catalyst support
Process for preparing a catalyst support which process comprises a) mixing pentasil zeolite having a bulk silica to alumina molar ratio in the range of from 20 to 150 with water, a silica source and an alkali metal salt, b) extruding the mixture obtained in step (a), c) drying and calcining the extrudates obtained in step (b), d) subjecting the calcined extrudates obtained in step (c) to ion exchange to reduce the alkali metal content, and e) drying the extrudates obtained in step (d); process for preparing a catalyst by furthermore impregnating such support with platinum in an amount in the range of from 0.001 to 0.1 wt % and tin in an amount in the range of from 0.01 to 0.5 wt %, each on the basis of total catalyst; ethylbenzene dealkylation catalyst obtainable thereby and a process for dealkylation of ethylbenzene which process comprises contacting feedstock containing ethylbenzene with such catalyst. |
US09604200B2 |
Steam reforming
A process for the steam reforming of hydrocarbons comprises partially oxidizing a feedgas comprising a hydrocarbon feedstock with an oxygen-containing gas in the presence of steam to form a partially oxidized hydrocarbon gas mixture at a temperature >1200° C. and passing the resultant partially oxidized hydrocarbon gas mixture through a bed of steam reforming catalyst, wherein the bed comprises a first layer and a second layer, each layer comprising a catalytically active metal on an oxidic support wherein the oxidic support for the first layer is a zirconia. |
US09604196B2 |
Size-selective hemocompatible polymer system
A size-selective hemocompatible porous polymeric adsorbent system is provided, the polymer system comprises at least one crosslinking agent and at least one dispersing agent, and the polymer has a plurality of pores with diameters in the range from about 17 to about 40,000 Angstroms. |
US09604192B2 |
Pyrolysis and gasification systems, methods, and resultants derived therefrom
A process and system for the controlled thermal conversion of a carbonaceous feedstock, including: exposing the feedstock to one or more predetermined temperatures and one or more predetermined pressures for one or more predetermined amounts of time in one or more chambers to produce a gas product and a solid product, wherein the gas product includes one or more of methane, Carbon monoxide, Hydrogen, and one or more noxious chemicals and the solid product includes Carbon and Carbon nano-structures; sequestration enabling at least a portion of the Carbon by creating associated Lewis Acid Sites; sequestering at least one of the one or more noxious chemicals in the one or more chambers using the sequestration enabled Carbon; and controlling the constituents of the gas product using feedback, thereby providing a predictable and stable gas product from an unknown and/or variable feedstock and communicating data via SmartGrid communications protocols. |
US09604190B2 |
Method for preparing stiffened capsules
The present invention relates to a method for preparing capsules comprising a liquid core, a stiffened intermediate envelope and a gelled external envelope, comprising a step of forming a multi-component liquid drop, a gelification step and a stiffening step.The present invention also relates to a method for preparing capsules comprising a liquid core and a stiffened envelope, comprising a step of forming a multi-component liquid drop, a gelification step, a stiffening step and a depolymerizing step. |
US09604188B2 |
Methods and systems for promoting hydrogen gas distribution within cellulosic biomass solids during hydrothermal digestion
Methods and systems for promoting hydrogen gas distribution within cellulosic biomass solids during hydrothermal digestion. One exemplary method can comprise providing cellulosic biomass solids in a hydrothermal digestion unit in the presence of a digestion solvent and a slurry catalyst capable of activating molecular hydrogen; and heating the cellulosic biomass solids and the digestion solvent in the presence of molecular hydrogen, thereby forming an alcoholic component derived from the cellulosic biomass solids, at least a portion of the molecular hydrogen being introduced to the hydrothermal digestion unit via a plurality of spaced apart fluid inlets vertically disposed about the height of the hydrothermal digestion unit. |
US09604185B2 |
Apparatus for indexing and agitating fluid containers
An apparatus configured for mixing the contents of one or more fluid containers includes a fluid container support platform configured to hold one or more fluid containers. The fluid container support platform is configured to index the container to one or more specified locations and to be moved in an orbital path about an orbital center independently of the rotation about the central axis of rotation. The apparatus further includes an indexing drive system configured to effect indexing movement of the container support platform and a vortex drive system configured to effect powered orbital movement of the container support platform about the orbital center. An evaporation limiting insert placed within containers reduces exposure of the fluid contents of the container to atmospheric air, thereby reducing susceptibility of the fluid contents to evaporation. |
US09604182B2 |
System for transporting solids with improved solids packing
A system includes a solid feed pump having a housing, a rotor disposed in the housing, a curved passage disposed between the rotor and the housing, a solid feed inlet coupled to the curved passage, and a solid feed outlet coupled to the curved passage. Also, a solids packing device is coupled to the solid feed inlet of the solid feed pump. The solids packing device includes a first channel configured to receive a solid feed with a first range of sizes, a second channel configured to receive transport assisting particles (TAP) with a second range of sizes. The first range is different from the second range. A third channel is configured to receive and mix the solid feed and the TAP to provide a solid feed-TAP mixture with the TAP filling interspatial spaces between the solid feed. The third channel is coupled to the solid feed inlet. |
US09604179B2 |
Spiral membrane element and method of producing the same
A spiral membrane element that can reduce the dimension increase in the length direction is provided. Also, a method for producing a spiral membrane element is provided having a step of forming a fiber reinforced resin layer having a reinforcing fiber layer and a strengthening fiber layer. The spiral membrane element is provided with a cylindrical wound body in which a separation membrane, a feed-side channel material, and a permeate-side channel material in a laminated state are wound in a spiral form around a center tube having a hole, and a sealing part for preventing feed-side fluid and permeate-side fluid from being mixed with each other, wherein a fiber reinforced resin layer having a reinforcing fiber layer and a strengthening fiber layer enclosed and buried with the same resin is provided on an outer circumferential side of the cylindrical wound body. |
US09604173B2 |
Purification column
A purification column is provided in which fluid is purified by flow through a purifying component. The column includes an annular wall defining a bore which, in use, contains the purifying component. The column further includes an inlet port to the bore comprising a first aperture through the annular wall, the inlet port being adjacent one end of the column. The column further includes an outlet port from the bore comprising a second aperture through the annular wall, the outlet port being adjacent the same end of the column as the inlet port. The column further includes a flow guidance device within the bore and removably connected to the inlet and outlet ports for guiding the fluid to the purifying component from the inlet port and for guiding the fluid from the purifying component to the outlet port. The flow guidance device maintains separation of the fluid flows to and from the purifying component. |
US09604171B2 |
Filter group
A filter cartridge including a filter membrane and at least a support element fixed to the filter membrane, the support element being provided with at least a snap-engaging element suitable for snap-engaging to a support body following a reciprocal translation between the filter cartridge and the support body along a nearing axis, the support element further including a disengaging device suitable for disengaging the snap-engaging element from the support body following a reciprocal rotation between the filter cartridge and the support body about the axis. |
US09604168B2 |
Hybrid felts of electrospun nanofibers
The present invention relates generally to compositions for use in biological and chemical separations, as well as other applications. More specifically, the present invention relates to hybrid felts fabricated from electrospun nanofibers with high permeance and high capacity. Such hybrid felts utilize derivatized cellulose, and at least one non-cellulose-based polymer that may be removed from the felt by subjecting it to moderately elevated temperatures and/or solvents capable of dissolving the non-cellulose-based polymer to leave behind a porous nanofiber felt having more uniform pore sizes and other enhanced properties when compared to single component nanofiber felts. |
US09604167B2 |
Multistage high capacity and depth coalescing media system
A filter assembly having a first stage filter that filters particulates from fluid flowing through the filter and a second stage filter downstream of the first stage filter that coalesces water from the fluid. By providing the first stage filter upstream of the second stage filter, particulate filtration capacity and efficiency may be provided while protecting the second stage filter from particulates. Protecting the second stage filter from particulates allows for the life of the second stage filter to be extended while providing efficient emulsion removal in the filter assembly. |
US09604164B2 |
Fluid intake screen
A screen for intake of fluid. The screen includes parallel and spaced rods, filtration material, a fitting, and structural members. The rods may be distributed in a cylindrical configuration. The filtration material, in some embodiments spirally wrapped wire, is disposed around the rods to define an interior volume. The fitting is disposed at an end of the rods and adjacent to the filtration material. Each structural member, which in some embodiments are elongated bars, is interposed between adjacent rods. The structural members are welded to the adjacent rods, and the adjacent rods and the structural members are welded to the fitting to increase the effective weld area, the tensile strength of the connection, and potentially the overall strength of the screen. The screen may be used for a variety of fluids and installations, and is particularly suited to use in water wells. |
US09604162B2 |
Rotary disc filter device
A rotary disc filter device includes a rotor rotatable about an axis of rotation, having a plurality of disc-shaped filter members. Each disc-shaped filter member has two walls extending outwardly form the axis of rotation. At least one of the walls has the form of a frustum. |
US09604161B2 |
Rake system
In a rake system, a reamer element is attached to a reamer arm, which is movable backward and forward. A pivot axle of the reamer arm is formed on the distal end of a control arm, which is pivotable around a further pivot axle. During forward movement of the reamer arm, the reamer element pushes raked material collected by the rake to a discharge edge at the upper end of the rake. During backward movement of the reamer arm, the control arm is lifted, and the reamer element is moved back at a distance from the rake. |
US09604160B2 |
Partitioned water treatment systems with vertical filtration units
The present invention supplies partitioned water treatment systems that possess a plurality of chambers and vertical filtration units, and are operative to control and filter surface runoff water. Such systems are typically placed inline with surface runoff water conveyance system infrastructure, such as pipes, channels, and water storage units. |
US09604157B2 |
Pump with water management
A pumping system configured to pump fluid from the ambient environment to a target reservoir, the pumping system including: a fluid pump configured to statically mount to a rotating surface, the pump configured to rotate about an axis of rotation; a pump reservoir statically coupled to the fluid pump and configured to fluidly couple to the target reservoir, the pump reservoir including a collection area defined along a portion of the pump reservoir radially outward of the axis of rotation; and a liquid separation member arranged along a portion of the collection area, the liquid separation member including a membrane configured to preferentially permit liquid flow therethrough. |
US09604151B2 |
Water amusement device
A water amusement device includes a base pad that extends in a longitudinal direction and a lateral direction. A plurality of longitudinally-extending troughs is located on the base pad. Each longitudinally-extending trough has a respective channel opening that is connected to a laterally extending drain channel. A pad surface is located on the longitudinally-extending troughs and a water-distribution feature located on the pad surface. |
US09604148B2 |
Management server of game service and method of providing game service
A method that for increasing the number of users making a registration to a game service by providing a motivation to a registered user, a game player of the game service, to invite more users to a game. When a user registered to the game service invites a friend to a game, a benefit assignment screen may be displayed on an invitation screen. Corresponding benefits may be determined based on information such as a preference and a skillfulness of the friend about a second game, or personal information of the friend, such as age or sex. In addition, the benefits may be assigned only during a predetermined period of time and accordingly, the registered user may be motivated to invite the friend. |
US09604143B1 |
Systems and methods of playing a game on a mobile device
The system and/or method comprising: receiving, from a user on a computing device, input selecting a first country from a plurality of countries; receiving, from the user on the computing device, input selecting a first category of songs from a plurality of categories of songs; displaying, on the computing device, a chorus of a song from the selected category of songs, wherein the chorus is the main verse of the song; upon displaying the song on the computing device, displaying a timer indicating a predetermined threshold period of time; and displaying, by the computing device, a chorus of a second song from the selected category of songs, when the predetermined threshold period of time is exhausted. |
US09604141B2 |
Storage medium having game program stored thereon, game apparatus, game system, and game processing method
Operation input obtaining means obtains an operation input performed by a player with respect to an input device. Designated position setting means sets a designated position with respect to a virtual game world in accordance with the operation input. Biological signal obtaining means obtains a biological signal from the player. Designated position change means changes the designated position in accordance with the biological signal obtained by the biological signal obtaining means. Game processing means performs a predetermined game process on the basis of the designated position. |
US09604134B2 |
Device control system and method of determining altitude
A gaming system has a pressure measurement in the remote control (which may be the complete gaming apparatus) and this is used to derive a height of the remote control. In this way, barometric pressure measurement allows precise determination of the altitude of the game controller. The altitude information is then used to control the game. |
US09604133B2 |
Touch-controlled game character motion providing dynamically-positioned virtual control pad
Methods and apparatus for controlling movement of a digital object displayed on a screen provide a virtual dynamic direction control pad based on zone detection and touch stroke direction to control customized animated character motion. A player wishing to move the digital object can use a stylus or other touch to indicate a first point on the screen. When the player first touches the stylus to the screen, the system analyzes the touch and divides the screen into multiple zones around the first point indicated by the player. To move the object, the player moves the stylus to a second point on the screen. Movement of the stylus to a second point within one of these zones causes the digital object to perform a predetermined action. Each zone has a predetermined associated action. Direct control of character motion by the game player is enhanced. |
US09604131B1 |
Systems and methods for verifying player proximity within a location-based game
Systems and methods for verifying player proximity within a location-based game are disclosed. In one aspect, a method for verifying player proximity may include receiving a request associated with verifying the proximity of a first player of the location-based game relative to a second player of the location-based game and transmitting a visual indicator to a first client of the first player, wherein the visual indicator is associated with a data record configured to expire within a predetermined time period. In addition, the method may include receiving a copy of the visual indicator from a second client of the second player and determining whether the copy of the visual indicator was received prior to the expiration of the data record. |
US09604123B2 |
Bushing, skateboard truck and skateboard
This application provides skateboards and skateboard trucks. |
US09604119B2 |
Golf alignment rod holder
Embodiments of the invention include an alignment rod holder that holds an alignment rod at different angles to provide reference points and feedback for golf practice drills. The device is comprised of a centerpiece, which holds the alignment rod, and two base pieces. |
US09604117B2 |
Golf stroke training device
A golf stroke training device and system allowing a user to obtain feedback regarding a golf stroke without moving from a stance and capable of detecting the orientation and velocity of a leading edge of a golf club. A data processing unit filters out non-relevant inputs from the sensors and only evaluates valid simulated forward strokes so that the data processing unit may evaluate a plurality of non-stop practice strokes. |
US09604103B2 |
Monofin, tail and method
A monofin, mermaid tail, and method of applying the tail and monofin. The fin utilizes a core made of flexible yet resilient material such as plastic and a cover that is elastic, such as neoprene. The user's feet are connected to the fin by releasable connections including a securing cord and cord lock. The mermaid tail and monofin connects both of a user's feet and legs in order to facilitate swimming in a mermaid-like motion while giving the user the appearance of a mermaid. |
US09604102B2 |
Exercising apparatus
An apparatus is disclosed for enabling an operator to exercise comprising a frame having a body, a base and a top. A load is positioned on the frame for providing a resistive force. A press is positioned on the frame for displacement by the operator. A linkage joins the load with the press for displacing the load upon displacement of the press by the operator. An arm extends between a support end and a user end. A support pivot secures the support end of the arm to the top of the frame for pivoting the arm about the frame. A user interface inputs and outputs data. A user pivot securing the user interface to the user end of the arm for pivoting the user interface about the arm. |
US09604101B2 |
Golf swing analysis device and golf swing analysis method
A golf swing analysis device includes a joint force calculation section and a torque extraction section. The joint force calculation section generates a double pendulum model that includes a first link that corresponds to an upper part of a body of a golfer, a second link that corresponds to a golf club, and a joint that links the first link and the second link, and calculates a joint force applied to the joint along with a swing motion using an acceleration measured by an inertial sensor attached to the golf club. The torque extraction section extracts a torque that causes the second link to make a rotational motion around a first axis from the joint force. |
US09604099B2 |
Positional lock for foot pedals of an elliptical exercise machine
An elliptical exercise machine includes a first foot pedal and a second foot pedal attached to a frame to travel along reciprocating paths. A resistance mechanism is also integrated into the elliptical exercise machine to resist movement of the first and second foot pedals along the reciprocating paths. A locking mechanism is arranged to secure the first and second foot pedals in place and prevent them from moving when the locking mechanism is in a secured mode. The locking mechanism is in communication with a locking input mechanism and is arranged to switch between the secured mode and an operational mode that allows the first and second foot pedals to travel in response to user input received through the locking input mechanism. |
US09604094B2 |
Portable exercise machine
A portable exercise machine is provided for rotator cuff exercise. The portable exercise machine includes a flat board having an upper surface and a U-shaped cutout for receiving a torso of a user. A pair of opposing, rotatable arms are affixed to the upper surface of the flat board. The distal end of each arm includes a handle adapted to be grasped by a user and the proximal end of each arm is pivotally coupled to a steel coil. The steel coil provides resistance against the rotation of the distal end of the arms. The steel coil can be removably affixed to an inner connection region or an outer connection region of the flat board. The outer connection region provides resistance for inward movement of the arms and the inner connection region provides resistance for outward movement of the arms. |
US09604093B2 |
Exercise device and method of using the same
An exercise device may comprise first and second elongated support members, at least one brace member for holding the first and second support members in a spaced apart relation to each other and a limb support device being disposed between the first and second support members and being interconnected thereto for sliding longitudinal relative to the first and second support members. |
US09604088B2 |
Resistance training devices, systems, and methods
Systems, devices, and methods for providing weighted resistance to swimmers are provided. The device can be portable and easy to use and set-up. In one exemplary embodiment, a resistance training device includes opposed pulley modules having a rope disposed between one or more pulleys of each of the two modules, a weighted component associated with one end of the rope, an attachment mechanism for attaching the device to a substantially fixed location, and a user interface for associating another end of the rope with a user. In use, the device can be fixed to a substantially fixed location, such as a dive block, and can provide resistance based, at least in part, on the amount of weight associated with the weighted component disposed in the water. Other systems, devices, and methods are also provided. |
US09604087B2 |
Rope climbing systems and methods of use
Various apparatuses for rope-climbing and associated methods are provided. Embodiments include a circular loop of rope and a variable braking system allowing for a freely suspended rope-climbing experience a safe distance from the ground and at a speed variable to individual users. |
US09604086B2 |
Assisted chin/dip exercise apparatus with adjustable chin-up/pull-up handles
An assisted chin/dip exercise apparatus has a main frame and an assist or foot bar pivotally mounted on the frame and linked to a weight stack or resistance for assisting a user standing on the foot bar during performance of chin and dip exercises. The main frame has a first, overhead handle assembly and a second, dip handle assembly below the first handle assembly. The first handle assembly includes a pair of adjustably mounted handles freely pivotable between a first, chin-up position in which the handles extend towards one another at a rearward angle with a small spacing between the handles and a second, pull-up position in which the handles extend in a forward direction and are spaced apart by a larger spacing sufficient to provide head clearance for a user stepping onto the foot bar or while performing a dip exercise. |
US09604082B2 |
Fore-grip handled fire-extinguisher
A fore-grip specially suited and configured to mount upon a tank-style fire-extinguisher for use as a defensive tool, the fore-grip including a handle that mounts near the base or bottom-end of the extinguisher tank. A tank bracket is attached to the tank of the fire extinguisher with the fore-grip mounted to the bracket, which can include a clip for the extinguisher nozzle. A user is able to concurrently grasp the handle of the fore-grip to lift and to lift and aim the fire-extinguisher, while opening the manual valve to discharge the pressurized propellant from the nozzle. |
US09604077B2 |
Visualizing radiation therapy beam in real-time in the context of patient's anatomy
A method of real-time radiotherapy beam visualization is provided that includes disposing a free-form flexible scintillating sheet on a subject of interest, irradiating the subject of interest with a source of ionizing radiation, where the free-forming flexible scintillating sheet emits light when irradiated by the therapeutic photon beam, collecting the emitted light and collecting ambient light reflected from the subject of interest and surrounding objects using a camera, where the collected light is converted to image data by the camera, where the image data is communicated to an appropriately programmed computer, and processing the image data to determine beam characteristics and the characteristics of the subject of interest, using the appropriately programmed computer, where the beam characteristics and the characteristics of the subject of interest are displayed in real-time to a machine operator enabling real-time verification of treatment delivery. |
US09604076B2 |
Radiation containing seeds and method for high visibility magnetic imaging
A radioactive seed and method for making a radioactive seed with selective magnetic imaging characteristics are provided. The seed includes a housing which may include a metal shell for at least partially enclosing a radioactive material. The shell encloses a rod having a nickel layer with a phosphorous content, wherein the phosphorous content includes a level of phosphorous sufficient, when the seed is implanted in tissue, to provide a magnetic resonance image of the seed while substantially eliminating gross artifacts in the magnetic resonance image. |
US09604075B2 |
Method for the operation of a radiotherapy system and a radiotherapy system
A method for calculating local part radiation doses in a radiotherapy system for applying a total radiation dose in a target volume with several beams is provided. The method includes determining at least one first control plane for controlling the dosing of the beams, determining at least one second control plane for controlling the positioning of the beams, and allocating beams to the first and second control planes. The method also includes, for at least one side of a first control plane, calculating in isolation of the corresponding local part radiation doses of all the beams allocated to the first control plane. |
US09604069B2 |
Defibrillator and method using limb leads for artifact free ECG
A defibrillator and method that uses ECG signals from limb lead electrodes for display and monitoring, even when a separate set of therapy pads are present at the patient. The limb lead ECG signal is used for display and to determine whether electrotherapy is necessary. The determination is a prerequisite to arming and delivery of the electrotherapy. |
US09604068B2 |
Systems and methods for making and using improved connector contacts for electrical stimulation systems
A connector for an implantable electrical medical device includes a connector lumen defined in an elongated connector housing and adapted for receiving a portion of a lead. Connector-contact assemblies are disposed in the connector lumen. Each of the connector-contact assemblies includes a contact housing. Multiple connector contacts are arranged along perimeters of inner surfaces of the contact housings such that the connector contacts are not in electrical contact with one another. Each of the connector contacts includes a biasing structure that physically contacts terminals disposed along the lead when the lead is received by the connector lumen. For each connector contact of a particular connector-contact assembly, the biasing structure extends around no more than 70% of the perimeter of the inner surface of the contact housing and is circumferentially-offset from the biasing structures of the remaining connector contacts of the connector-contact assembly. |
US09604064B2 |
Criteria for optimal electrical resynchronization during fusion pacing
Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a plurality of left ventricular electrodes. Pacing using a first one of the left ventricular electrodes and measuring activation times at other ones of the left and right ventricular electrodes. Pacing using a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing weighted sums of the measured activation times to measure a fusion index and select one of the left ventricular electrodes for delivery of subsequent pacing pulses based on comparing fusion indices during pacing from different LV electrodes. One or more embodiments use the same fusion index to select an optimal A-V delay by comparing fusion indices during pacing with different A-V delays at resting atrial rates as well as rates above the resting rate. |
US09604056B2 |
Methods and systems for treating neurological movement disorders
The present disclosure provides methods for reducing the clinical presentations of a neurological movement disorder in a subject. Aspects of the methods include measuring cortical local field potentials (LFPs) from the subject's brain, calculating a modulation index related to brain synchronization from the LFPs, and administering deep brain stimulation to the subject if the calculated modulation index is outside of a threshold range. Also provided are devices, systems, and kits that may be used in practicing the subject methods. |
US09604055B2 |
Microfabricated surface neurostimulation device and methods of making and using the same
Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an supportive backing layer. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as along a region of a cortex of a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation. |
US09604054B2 |
Device, system, methods, and computer readable media for managing acute and chronic pain
Methods, devices, control modules, and computer readable media are provided for managing acute and chronic pain in subjects. More specifically, a method is provided for reducing pain in a subject that includes delivering to the subject a series of stimuli consisting of both painful and non-painful stimuli. A portion of each of the painful and the non-painful stimuli is delivered to the subject during a systolic phase of the subject's cardiac cycle and the remaining portion of each of the painful and the non-painful stimuli is delivered during a diastolic phase of the subject's cardiac cycle. |
US09604053B2 |
Methods and apparatus for lead placement on a surface of the heart
The methods and apparatus for lead placement on a surface of the heart are employed using an elongated body having proximal and distal end portions. The body defines a lead receiving passageway extending between a proximal inlet and a distal outlet for receiving a lead therethrough for contact with the heart surface. The elongated body is adapted for insertion between a pericardium and an epicardial surface. At least a portion of the body may have a non-circular cross-sectional shape adapted to retain the body orientation between the pericardium and the epicardial surface. |
US09604050B2 |
Systems and methods for percutaneously implanting into a patient a paddle lead of an electrical stimulation system
A multi-needle paddle lead introducer includes a needle assembly, a hub assembly, and a sheath. The needle assembly includes at least one primary needle and at least one secondary needle. The secondary needle is coupled to the primary needle along a portion of the longitudinal length of the needle assembly such that the primary needle and the secondary needle are arranged in a side-by-side configuration. The secondary needle is configured and arranged to move relative to the primary needle along the longitudinal length of the needle assembly. The hub assembly includes a primary needle hub coupled to a proximal end portion of the primary needle and a secondary needle hub coupled to a proximal end portion of the primary needle. The sheath is configured and arranged for disposing over a portion of an outer surface of the needle assembly and for sliding along the longitudinal length of the needle assembly. |
US09604046B2 |
Protective caps for use with medical fluid fittings, and related methods
A protective cap for use with a medical fluid fitting including a fitting thread and a sealing portion having a sealing surface. The protective cap includes a body having a proximal end, a distal end, and a cap thread extending axially. The cap thread is configured to threadedly engage the fitting thread for releasably coupling the protective cap with the medical fluid fitting, and defines a tapered engagement surface. The tapered engagement surface tapers axially relative to a longitudinal axis of the body, and is configured to frictionally contact the fitting thread for retaining the protective cap in coupling engagement with the medical fluid fitting. The protective cap is configured to peripherally surround the sealing portion such that no portion of the protective cap contacts the sealing surface when the protective cap is coupled with the medical fluid fitting. |
US09604044B2 |
Connection device for use in the negative pressure treatment of wounds
A connection device for use in the negative pressure therapy of wounds, includes a flexible conduit having at least two lumens and being constructed for impingement with negative pressure and/or fluid media; a coupling body made of an elastomeric flexible material, and non-detachably molded onto a wound-side end section of the conduit and being constructed for arrangement on a negative pressure bandage which covers the wound and seals the wound against the atmosphere, wherein the conduit communicates with a wound space through at least one opening in the coupling body; and a fluid inlet section for insertion through an opening in the negative pressure bandage into the wound space. The fluid inlet section is formed on the coupling body and protrudes over a walling of the coupling body, which walling faces the negative pressure bandage. The fluid inlet section is fluidly connected interiorly of the coupling body with a further lumen for delivering a fluid medium. The further lumen is formed inside the conduit or by a fluid delivery line leading to the coupling body. |
US09604043B2 |
Capacitive fluid level sensing
A capacitive fluid level sensing arrangement for use in a medical device is provided. The arrangement includes at least one pair of conductive plates configured to increase and decrease the amount of electric charge stored in relation to the level of fluid within a fluid maintaining device, such as a reservoir. The conductive plates are electrically connected to a medical device and are configured to measure the charge stored between the plates and thus sense the fluid level. The electric circuit may communicate the measurement to an instrument host arrangement for operating a pump configured to remove fluid from the reservoir and move the fluid to a collector when the level exceeds a preset upper level amount. The instrument host arrangement may stop operating the pump when the fluid level is reduced to a preset lower level amount. |
US09604040B1 |
System and methods for performing spinal fusion surgery
A system and method for performing spine surgery, including a tissue distraction assembly. The tissue distraction assembly includes an initial dilator, a secondary dilator, a first expander, and a second expander. The tissue distraction assembly is provided with an overall generally oblong shape. The tissue distraction assembly provides for asymmetrical tissue distraction in a single direction. |
US09604036B2 |
Cutting balloon with connector and dilation element
A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements. |
US09604029B2 |
Emulation of sensory stimuli, emanating from a reference person, for a child
A device for generating sensory stimuli, corresponding to sensory stimuli emanating from a reference person, for a child comprises a receiving unit for receiving a data stream from a device for acquiring sensory stimuli, emanating from a reference person, and a transducer unit, which is coupled to the receiving unit and is controllable by the data stream. The transducer unit generates at least either body-borne sound, which corresponds to the heart sounds, described by the data stream, of the reference person, or movements, which correspond to the movements, described by the data stream, of the reference person, or airborne sound, which corresponds to the airborne sound generated by the reference person and is described by the data stream. |
US09604026B2 |
Medical carbon monoxide delivery system
A medical carbon monoxide generator provides for a solid carbon material that may be heated at substantially normal atmospheric pressure to provide a source of medical quality carbon monoxide. The heating source may be an electrical filament or laser controllable by a microcontroller to provide accurate delivery rates and amounts. In one embodiment, a replaceable cartridge holding the carbon material may be used. |
US09604025B2 |
Patient interface assembly with improved stabilization
A patient interface assembly includes a support member having a central support portion and a pair of cheek mount supports coupled to the central portion. Each cheek mount support applies a force on or on a side of a user's cheekbone. A seal member is coupled to the support portion and seals against the user. An additional nasal support member is provided that includes a first lateral side member operatively coupled to the central support portion and arranged to be disposed along a first side of a user's nose, and a second lateral side member also operatively coupled the central support portion and arranged to be disposed along a second side of a user's nose. At least a portion of the first lateral side member and the second lateral side member is rigid or semi rigid. |
US09604024B2 |
Divided cannula with each nare communicating with each flow path
A divided cannula comprising a cannula body which is divided by a partitioning wall into first and second flow chambers. The first flow chamber has first and second spaced apart nare passages while the second flow chamber has first and second spaced apart nare passages. The cannula body supports spaced apart first and second nares and each of the first and the second nares defines a common nare passage. The first nare passage of the first internal flow chamber and the first nare passage of the second internal flow chamber both communicate with the common nare passage of the first nare and the second nare passage of the first internal flow chamber and the second nare passage of the second internal flow chamber both communicate with the common nare passage of the second nare. A pressure sensing line and a gas supply line interconnected to the divided cannula with a gas supply system. |
US09604021B2 |
Automatic control system for mechanical ventilation for active or passive subjects
A method and an apparatus for controlling a ventilator to automatically adjust ventilation assistance to an active or passive subject. The method includes determining volume and flow rate of gas to the patient during inspiration on an ongoing basis, and generating control signals in proportion to the volume and flow rate of gas to the patient wherein proportionality factors, and support levels for the elastic and resistive components of pressure are automatically adjusted by the ventilator. The ongoing pressure applied by the ventilator is a sum of elastic and resistive pressures that are automatically controlled by the system. When the patient breathes spontaneously, the support levels are automatically adjusted based on the patient's requirements. If the patient does not breathe spontaneously, the ventilator provides ventilation at an optimal level and rate. The method may be used in weaning or in a management phase of ventilation. |
US09604020B2 |
Integrated, extendable anesthesia system
The anesthesia systems have an integrated, extendable clinical center and clinician/anesthesia office that accommodates for a physical separation of clinical and clerical functions. The anesthesia system includes an alarm reversion system which enables a predefined alarm limit to be set and then to be automatically reverted back to an alarm limit existing just before the predefined alarm limit was set. |
US09604019B2 |
Detection system and method for aerosol delivery
An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to the detector and to the pressure sensor, and is configured to receive at least a signal from the detector and the pressure sensor. The processor is further configured to use the received signals to calculate a volume of the first aerosol, and to output an output signal associated with the calculated volume. The various measurements can be repeated and compared, and the output signal can be a feedback signal for metering subsequent amounts of the aerosol, based on the comparison. |
US09604017B2 |
Needle for piercing a powder capsule for inhalation
The invention relates to a powder inhaler with at least one specially sharpened needle, to ensure the precise piercing or cutting open of capsules and hence the optimum delivery of powdered medicament compositions, medicament formulations or medicament mixtures, as well as ensuring that little effort is needed to perforate or cut open the capsule. |
US09604010B2 |
Retractable syringe needle
A retractable needle is provided for a syringe comprising a barrel and a plunger that comprises a portion capable of engaging the retractable needle for retraction. The retractable needle comprises a cannula, a needle body having a plunger-engaging member, at least one aperture and an elongate portion which houses the cannula, the cannula comprising an end which is in fluid communication with the at least one aperture, wherein the at least one aperture is located between the plunger-engaging member and the elongate portion. The positioning of the at least one aperture distal to the plunger-engaging member maximizes the efficiency of fluid delivery. |
US09604006B2 |
Cartridge with adjustable filling volume
The present invention relates to a cartridge for a drug delivery device, comprising a barrel of substantially cylindrical shape and at least one piston arrangement displaceably arranged in the barrel, wherein the piston arrangement occupies at least 20% of the volume confined by the barrel. |
US09604004B2 |
Drug delivery device and logging module assembly
A drug delivery assembly comprises a drug delivery device, an electronic dose logging module releasably attachable to the drug delivery device, and a cap releasably attachable to the logging module to cover an outlet portion of a mounted drug reservoir. The logging module and the drug delivery device comprise mating snap coupling means. The logging module comprises locking means acting on the locking module snap coupling means, wherein the locking means is actuated from the unlocked to the locked state when the cap is attached to the logging module in a first direction, and the locking means is actuated from the locked to the unlocked state when the cap is detached from the logging module in a second direction opposed to the first direction. |
US09604001B2 |
Device and method for food management
A medical device is disclosed. The medical device includes an RFID reader for receiving information from at least one RFID transponder. The medical device also includes a memory for storing a database and at least one processor for processing information. Also, a remote controller for a medical device is disclosed. The remote controller includes an information receiver for receiving information related to food. The infusion device also includes a memory for storing a database and at least one processor for processing information. A method for use in a medical device is also disclosed. The method includes receiving information from an RFID transponder related to food. Also, the processing the information by comparing the information to a database is included in the method. The method also includes determining the acceptability of the food and providing information related to acceptability to the user. |
US09603998B2 |
Micro-fluidic chambers for use in liquid medicament delivery systems
Micro-fluidic chambers for use in a liquid medicament delivery system, include a bottom substrate and a top cover, the top cover being spaced from the bottom substrate so as to define a height of the chamber, wherein, one or more walls or fillings are positioned in the chamber, the walls or fillings defining a fluid channel there between such that the fluid channel extends from an inlet of the chamber to an outlet of the chamber, wherein, each of the walls or fillings has a height less than the height of the chamber so as to define a fluid gap between a top surface of each wall or filling and the top cover; and wherein, the dimensions of the walls or fillings and the chamber are such that the fluid gap will be filled with liquid by capillary forces via the fluid channel when liquid is introduced into the fluid chamber. |
US09603997B2 |
Implantable drug pumps and refill devices therefor
Implanted drug pump devices can be refilled with a refill needle inserted through a fill port in the drug reservoir of the drug pump device. Proper needle insertion may be verified visually or using electrical, magnetic, optical, acoustic, or other suitable sensing mechanisms. |
US09603995B2 |
Device and method for setting therapeutic parameters for an infusion device
Embodiments are directed to infusion devices, systems, and methods to detect a capacity of a collapsible fluid reservoir of an infusion cartridge and/or a volume of a fluid disposed in the collapsible fluid reservoir or some other parameters of the infusion cartridge, and setting corresponding therapeutic parameters of an infusion device. Embodiments may include, obtaining data on the volume of fluid in the collapsible fluid reservoir, analyzing the obtained data to determine the setting of therapeutic parameters, and setting one or more therapeutic parameters of an infusion device. |
US09603992B2 |
Access port identification systems and methods
An access port for subcutaneous implantation is disclosed. Such an access port may comprise a body for capturing a septum for repeatedly inserting a needle therethrough into a cavity defined within the body. Further, the access port may include at least one feature structured and configured for identification of the access port subsequent to subcutaneous implantation. Methods of identifying a subcutaneously implanted access port are also disclosed. For example, a subcutaneously implanted access port may be provided and at least one feature of the subcutaneously implanted access port may be perceived. Further, the subcutaneously implanted access port may be identified in response to perceiving the at least one feature. |
US09603989B2 |
Methods for anticoagulating blood
Methods are provided for anticoagulating blood. Whole blood is drawn from a donor into a system at a draw flow rate. Anticoagulant from an anticoagulant source is pumped into the system at an anticoagulant flow rate to mix with the blood. The anticoagulated blood may be subsequently processed in any of a number of known ways, including separating it and removing at least a portion of one of the components of the blood. Thereafter, at least a portion of the remaining blood may be returned to the donor. The anticoagulant flow rate is independent of the draw flow rate and can be based on a number of factors, including the weight of the donor and the rate at which the donor can metabolize the anticoagulant. |
US09603980B2 |
Layer-by-layer stereocomplexed polymers as drug depot carriers or coatings in medical devices
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque, and atherosclerosis in type 2 diabetic patients. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned. |
US09603979B2 |
Use of bacterial polysaccharides for biofilm inhibition
A method comprises preventing or inhibiting bacterial adhesion and/or bacterial biofilm development by treating a substrate with a composition of a soluble group II capsular polysaccharide obtained from a bacterial strain. |
US09603978B2 |
Plasma modified medical devices and methods
Coatings, devices and methods are provided, wherein the contacting surface of a medical device with at least one contacting surface for contacting a bodily fluid or tissue, wherein long-lasting and durable bioactive agents or functional groups are deposited on the contacting surface through a unique two-step plasma coating process with deposition of a thin layer of plasma coating using a silicon-containing monomer in the first step and plasma surface modification using a mixture of nitrogen-containing molecules and oxygen-containing molecules in the second step. The two-step plasma coating process enables the implantable medical device to prevent both restenosis and thrombosis under clinical conditions. The invention also relates to surface treatment of metallic and polymeric biomaterials used for making of medical devices with significantly improved clinical performance and durability. |
US09603975B2 |
Bioerodible polymer compositions
The present disclosure pertains to compositions that comprise (a) a bioerodible polyester network formed by reaction between reactive species that comprise a polyol and a polycarboxylate, wherein at least one of the polyol and polycarboxylate has a functionality of three or more, and (b) a bioerodible thermoplastic polymer. The present disclosure further pertains to methods of using such compositions and to medical devices that comprise such compositions. |
US09603971B2 |
Silk-based ionomeric compositions
Disclosed herein are pH-dependent silk fibroin-based ionomeric compositions and colloids, and methods of making the same. The state of the silk fibroin ionomeric compositions is reversible and can transform from a gel-like colloid to a more fluid-like solution, or vice versa, upon an environmental stimulus, e.g., pH. Thus, the silk-based ionomeric compositions and colloids can be applied in various industries, ranging from electronic applications to biomedical applications, such as sensors, gel diodes, absorbent materials, drug delivery systems, tissue implants and contrast agents. |
US09603969B2 |
Porous scaffold material, and method for producing same
Provided are a scaffold material that functions as a scaffold material for two weeks or more in vivo and causes substantially no foreign-body reaction, and a method for producing the scaffold material. Specifically, a porous scaffold material comprising collagen fibers is provided. |
US09603968B2 |
Methods of making high-strength NDGA polymerized collagen fibers and related collagen-prep methods, medical devices and constructs
The disclosure describes methods of making high-strength NDGA collagen and associated methods of preparing collagen preparatory material and medical bioprostheses. |
US09603965B2 |
System and method for delivery of a protease inhibitor
The disclosed invention provides a system and method of artificially retarding fibrin-based blood clot degradation via the sustained release of a protease inhibitor, such as, for example, aprotinin or tranexamic acid (“TA”). The sustained release of the protease inhibitor is accomplished through incorporation within a biodegradable polymer microsphere to produce a protease inhibitor formulation. Next, the formulation along with fibrinogen and thrombin is applied to a wound site where an outer surface of the polymer microsphere degrades in a proteolytic environment to expose and release the incorporated protease inhibitor to the surrounding hydrogel or sealant or clot matrix at the wound site. |
US09603957B2 |
Multiple pump evaporative media system
An evaporative media system having multiple media stages each served by a separate pump is disclosed. In one aspect, the evaporative media system has a first media stage and a second media stage. A first pump is provided that is configured to deliver water from the first compartment of the water storage tank to the first media stage. Additionally, a second pump is provided that is configured to deliver water from the first compartment of the water storage tank to the second media stage. Additional media stages and pumps may be provided as well. The disclosed configuration eliminates the need for individual staging valves, provides a higher level of operational redundancy, reduces electrical consumption, and can be provided at a lower cost, as compared to many existing systems. |
US09603955B2 |
System for radiation sterilization of medical devices
Disclosed herein is a method of radiation sterilizing a plurality of medical devices. |
US09603952B2 |
Treatment of metastatic tumors
The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress. |
US09603951B2 |
Methods and apparatus for synthesizing imaging agents, and intermediates thereof
The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located. |
US09603945B2 |
Heparosan polymers and methods of making and using same for the enhancement of therapeutics
Compositions, methods, and systems are disclosed for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying agent or vehicle which can modulate drug cargo pharmacokinetics and behavior within a mammalian patient. |
US09603943B2 |
Polyesteramide platform for site specific drug delivery
A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe. |
US09603942B2 |
Somatostatin-dopamine chimeric analogs
The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions. |
US09603937B2 |
Platform drug delivery system utilizing crystal engineering and theanine dissolution
A platform drug delivery system and a method of improving the delivery of low solubility pharmaceuticals utilizing crystal engineering and Theanine dissolution resulting in enhanced bioactivity, dissolution rate, and solid state stability. |
US09603936B2 |
Polyethylene glycol based prodrug of adrenomedullin and use thereof
The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders. |
US09603933B2 |
Composition for enteric hard capsules, and enteric hard capsule prepared using the composition
A composition for enteric hard capsules, and an enteric hard capsule prepared using the composition. The composition for enteric hard capsules may include polyol having at least three hydroxyl groups. During the storage of the enteric hard capsule prepared using the composition, the separation of salt from the capsule is delayed. |
US09603932B2 |
Intravaginal ring comprising polyurethane composition for drug delivery
Intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): Also, method comprising administering one or more pharmaceutically active substances to a patient in need thereof. |
US09603930B2 |
Liquid bendamustine formulation
The present invention provides stable bendamustine-containing pharmaceutical compositions suitable for long term storage. The compositions include bendamustine, a pharmaceutically acceptable salt, and/or a hydrate form thereof, a solvent mixture of N,N-dimethylacetamide and glycerin, and an antioxidant. The bendamustine-containing compositions have less than about 2% of total impurities after two month storage at 25° C./60% RH. The pharmaceutical compositions may be used for treating neoplastic diseases. |
US09603925B2 |
Compositions comprising TL1A-Ig fusion protein for the regulation of T regulatory cells, and methods for their use
Compositions comprising TL1A-Ig fusion proteins and methods of their use, e.g., for the treatment of diseases and disorders associated with antigen-specific immune responses, are described. Also described are combination therapies that include the administration of a TNFRSF25 agonist and an interleukin (e.g., IL-2) and/or an mTOR inhibitor (e.g., rapamycin). |
US09603924B2 |
Bovine virus vaccines that are liquid stable
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, and a sugar alcohol. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines. |
US09603923B2 |
Universal carrier for targeting molecules to GB3 receptor expressing cells
The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens. |
US09603920B2 |
Compositions and methods for treating influenza
The present application provides compositions and methods useful for treating influenza. As described herein, the compositions and methods are based on the development of peptides and peptide combinations which exhibit immunogenic properties against influenza. In some embodiments, the peptide combinations induce a protective response against multiple strains of influenza, e.g., seasonal strains of influenza or even the new pandemic influenza A (H1N1) virus of swine origin. |
US09603919B2 |
Method for prophylaxis of influenza using vaccine for intranasal administration
The present invention provides a vaccine composition for transnasal mucous membrane administration, which contains an influenza virus antigen, polyriboinosinic polyribocytidylic acid (poly (I:C)) or a derivative thereof and a carboxyvinyl polymer. The present invention also provides a prophylactic method of influenza, including a step of administering the vaccine composition at least once to the nasal mucosa of a subject in need thereof. |
US09603917B2 |
Immunologically active compositions
This invention provides a microparticle carrier system comprising of one or more proteins, peptides, nucleic acids, carbohydrates, lipids or other bioactive substances with or without targeting molecules attached. In addition, the invention also provides immune modulatory compositions and methods of eliciting protective immune responses both in uninfected and infected hosts as well as the induction of immune tolerance. |
US09603915B2 |
Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection
Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or morality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector. |
US09603911B2 |
Ribotoxin molecules derived from sarcin and other related fungal ribotoxins
The present application relates to modified T cell epitopes derived from fungal ribotoxins, including a-sarcin, clavin, gigantin, mitogillin, and restrictocin, as well as modified ribotoxin molecules comprising one or more of the modified epitopes. The modified ribotoxin molecules inhibit protein synthesis, like the wild type ribotoxins, but exhibit reduced immunogenicity as compared to the corresponding wild type ribotoxin. Another aspect relates to a fusion protein which comprises a modified ribotoxin fused or conjugated or otherwise linked to a targeting molecule that is effective for binding a target of interest. Another aspect relates to the use of the modified ribotoxin or fusion protein for treating or managing a disease or condition. |
US09603910B2 |
Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase (and relative pharmaceutical formulations) for the preparation of a dressing for topical treatment of various kinds of wounds, burns of varying depth, pressure sores, vascular ulcers and diabetic foot ulcers as well as for the treatment of hypertrophic and keloid scars. |
US09603905B2 |
Intranasal insulin administration for the minimization of anesthesia-induced memory loss
Intranasal administration of insulin for a predetermined period prior to anesthesia significantly prevented anesthesia-induced tau hyperphosphorylation and cognitive impairment and enhanced brain insulin signaling in mice. Intranasal insulin thus provides a treatment for prevention of anesthesia-induced tau pathology and increased risk for tauopathies in surgical patients and may be administered to a subject prior to anesthesia, such as by administering several doses of intranasal insulin for several consecutive days prior to any anesthesia. |
US09603904B2 |
Treating diabetes melitus using insulin injections with less than daily injection frequency
The present invention relates to an insulin derivative for the treatment of a condition or disease where administration of insulin will be of benefit, comprising administering, to a patient in need thereof, effective dosages of the insulin derivative, wherein said insulin derivative exhibits a prolonged profile of action and wherein said dosages are administered at intervals longer than 24 hours. |
US09603892B2 |
Peptide compound for inhibiting restenosis and promoting re-endothelialization and method for preparing the same
Provided are a peptide compound prepared by additional synthesis in a drug having an effect of inhibiting restenosis, a composition for inhibiting restenosis and promoting re-endothelialization including the peptide compound, and a stent having a surface coated by using the composition, in order to overcome a restenosis problem in the stent. |
US09603891B2 |
Peptide compound for inhibiting restenosis and promoting re-endothelialization and method for preparing the same
Provided are a peptide compound prepared by additional synthesis in a drug having an effect of inhibiting restenosis, a composition for inhibiting restenosis and promoting re-endothelialization including the peptide compound, and a stent having a surface coated by using the composition, in order to overcome a restenosis problem in the stent. |
US09603889B2 |
IAP antagonists
There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention. |
US09603885B2 |
Picrorhiza extract for prevention, elimination and treatment of infection diseases
An anti-viral composition comprising terpenes and fatty acids found in the Scophulariaceae family of plants is disclosed. It further comprises other lipophillic constituents and the aglycons of the glycosides occurring in said family of plants. Preferably, the composition is derived by extraction of the roots and rhizomes of mixtures of Picrorhiza kurrooa Royle, Picrorhiza scrophularflora Pennell and Neopicrorhiza scrophula iflora. Solvents and solvent combinations are disclosed. The composition is effective against both DNA and RNA viruses and against fungal, bacterial, parasitic and protozoal infections and diseases and also as a hepatoprotective, anti-hyperlipidemic, anti-diabetic and kidney-protective agent. Anti-bodies and vaccines for the cited diseases can be made by administration of the composition to animal or other subjects. |
US09603877B2 |
Isolated nucleotide molecule and method of sensing and killing of pathogenic microorganism
The present invention relates to an isolated nucleic acid molecule comprising (a) a first nucleotide sequence encoding a protein that detects the presence, amount or both of a pathogenic microorganism by forming a complex with a quorum sensing molecule produced by said pathogenic microorganism, (b) one or more second nucleotide sequence said one or more second nucleotide sequence being under control of a promoter that is induced by the complex of the protein encoded by the first nucleotide sequence and the quorum sensing molecule produced by said pathogenic microorganism and encoding (i) an antimicrobial peptide, wherein the antimicrobial peptide is effective against the pathogenic microorganism detected by the protein encoded by the first nucleotide sequence; and/or an antibiofilm enzyme wherein the antibiofilm enzyme is effective against the pathogenic microorganism detected by the protein encoded by the first nucleotide sequence; and (c) optionally a third nucleotide sequence encoding a protein that controls the motility of the host organism, wherein the protein that controls the motility of the host organism directs the motility of the host organism towards said pathogenic microorganism. A recombinant microorganism comprising the isolated nucleic acid molecule and a method of sensing and killing pathogenic microorganisms is also described. |
US09603865B2 |
Methods for the treatment of hepatitis B and hepatitis D virus infections
It is disclosed a method for treating hepatitis B virus infection or hepatitis B virus/hepatitis delta virus co-infection, the method comprising administering to a subject in need of such treatment a first pharmaceutically acceptable agent that comprises at least one phosphorothioated nucleic acid polymer and a second pharmaceutically acceptable agent that comprises at least one nucleoside/nucleotide analog HBV polymerase inhibitor. |
US09603864B2 |
Substituted nucleosides, nucleotides and analogs thereof
Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such as a Coronaviridae virus, a Togaviridae virus, a Hepeviridae virus and/or a Bunyaviridae virus infection with one or more nucleosides, nucleotides and nucleotide analogs. |
US09603863B2 |
Substituted nucleosides, nucleotides and analogs thereof
Disclosed herein are nucleosides, nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a Filoviridae virus infection with one or more nucleosides and/or nucleotide analogs. |
US09603862B2 |
Activation and activators of SIRT5
The invention provides a method of increasing a deacetylase activity of SIRT5 by contacting SIRT5 with an agent that binds SIRT5 and reduces the Km of SIRT5 for a substrate, thereby increasing the deacetylase activity of SIRT5. The invention also provides a method for treating a urea cycle disorder in a mammal, as well as a method of assaying a sirtuin modulator. |
US09603859B2 |
Methods and products for increasing the rate of healing of tissue wounds
Disclosed are methods for increasing the rate of healing of a tissue wound by administering a composition including a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA). Also disclosed herein are methods of promoting wound healing in a subject in need of such promotion, comprising administering a composition comprising a therapeutically effective amount of at least one CSA. Additionally, disclosed herein are compounds and compositions comprising at least one CSA, or a pharmaceutically acceptable salt thereof, for use in the treatment of a tissue wound. Kits comprising such compositions and instructions on such methods are also contemplated herein. |
US09603858B2 |
Compositions for preventing and treating an immune system disorder
The present invention relates to methods of treating, preventing, or decreasing the occurrence of a condition characterized by Th2 overactivation or impaired Th1, or mitigating symptoms associated with a condition characterized by Th2 overactivation or impaired Th1, comprising orally administering to a subject in need thereof an effective amount of a composition comprising a plant stanol and/or plant stanol ester. The present invention also relates to methods of improving the health status of a subject suffering from asthma and increasing the levels of IL-10 in a subject in need thereof. |
US09603857B2 |
Inflammatory disease model and method of treatment
Model and method of treating inflammatory diseases. Traditional treatments for such diseases include administering to the patient toxic anti-inflammatory drugs. Following stabilization of the symptoms, the drug doses are tapered down to minimize side effects, as a result of which inflammation remains high and the disease is rarely cured. A chemistry-based disease model concludes that irrespective of the role that inflammation plays in the disease, inflammation reduction will impede disease initiation and progression. Managing and controlling inflammatory diseases requires reducing inflammation to acceptable normal values. Non-toxic ways such as non-steroidal anti-inflammatory drugs, anti-inflammatory diets, and regular exercise allow such reduction in inflammation to normal values, thereby slowing down or arresting disease progression and allowing the discontinuation or reduction of toxic anti-inflammatory therapy while maintaining low inflammation using non-toxic therapy. |
US09603855B2 |
Injectable osteogenic formula and method of using same
Formulations and methods for growing hone in a site specific location using an osteogenic molecule such as a prostaglandin, and a delivery vehicle which is preferably a polymer matrix. |
US09603854B2 |
Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them
Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system. |
US09603849B2 |
Uses of orvepitant
This invention relates to the new use of the compound (I) or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing it for the treatment of pruritus and to combinations for such a use. |
US09603841B2 |
Vector delivery-based microbicides
A new class of anti-microbial agents and methods for preventing or reducing the risk of sexually transmitted infections and/or diseases is provided. Preferably, these anti-microbial agents are also contraceptive and, thus, also prevent or reduce the risk of unplanned pregnancies. The anti-microbial agents comprise a delivery vector having anti-microbial activity (and preferably contraceptive activity) coupled with a nitric oxide donor moiety. |
US09603839B2 |
Thioredoxin protein inhibitors and uses thereof
A method of treating a fungal infection in a subject including administering to the subject a therapeutically effective amount of a thioredoxin protein inhibitor to treat the fungal infection in the subject. |
US09603835B2 |
Use of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine for treating cancer and in particular for preventing and/or treating cancer metastases
The present invention relates to the use of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methyl-propyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine or one of the pharmaceutically acceptable salts thereof for treating cancer and particularly in preventing and/or treating cancerous metastases. |
US09603833B2 |
Benzene or thiophene derivative and use thereof as VAP-1 inhibitor
The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof. |
US09603830B2 |
Compositions and methods for preventing and recovery from detrimental effects of alcohol consumption
Disclosed are compositions, devices, and methods to prevent and recover from detrimental effects of alcohol consumption, including significant undesirable symptoms of a hangover consciously felt by the alcohol consumer, as well as those that may not be consciously experienced. The present technology comprehensively targets multiple negative effects of hangovers. In one aspect, a composition includes dihydromyricetin (DHM); and N-acetyl cysteine (NAC). The composition may further include Prickly Pear Extract, Milk Thistle, Ginger Root, Vitamins B, C, and E, electrolytes, and/or sugars. |
US09603828B2 |
Sulforaphane isolation and purification
The present invention relates to methods of isolating and purifying sulforaphane. More specifically, the present invention relates to methods of isolating and purifying sulforaphane from natural sources. The present invention also relates to methods of forming high purity complexes of sulforaphane with cyclodextrin. |
US09603825B2 |
Compositions and methods of use of phorbol esters
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of cytopathic diseases. Cytopathic diseases may be caused by a variety means such as viral infections like HIV and AIDS in a mammalian subject. The methods and compositions of the invention are effective for inhibiting de novo HIV infection, upregulating viral expression from latent provirus, inhibiting HIV-induced cytopathic effects, down regulating the HIV receptor, increasing ThI cytokine expression, and decreasing Th2 cytokine expression. Additional compositions and methods are provided which employ a phorbol ester or derivative compound in combination with at least one additional agent such as those used in HAART protocols or therapeutic agents used to treat opportunistic infections due to HIV in mammalian subjects. |
US09603822B2 |
Therapeutic compositions
Ingenol angelate is a potent anticancer agent, and can be stabilised by dissolving it in an aprotic solvent in the presence of an acidic buffer. |
US09603820B2 |
Ornithine aminotransferase inhibition with GABA analogues for treatment of hepatocellular carcinoma
Therapeutic methods relating to the use of GABA-AT inhibitor compounds for the treatment of hepatocellular carcinoma. |
US09603818B2 |
S isomers of alpha-methyl-hydrocinnamic acid for the treatment of blood disorders
The present intervention generally relates to compositions comprising S-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood disorders and blood deficiencies, as well as methods for treating blood disorders and/or blood deficiency in a subject by administering a composition comprising S-isomer of alpha-methyl-hydrocinnamic acid to the subject to ameliorate at least one symptom associated with the blood disorder. Another aspect relates to administration of an S-isomer of alpha-methyl-hydrocinnamic acid stimulate multi-lineage hematopoietic cell production in a subject, for example, increasing the numbers of circulating neutrophils, erythrocytes and platelets. Accordingly, one aspect of the present invention relates to administration of S-isomer of alpha-methyl-hydrocinnamic acid, e.g., by oral administration to a subject for the treatment of blood disorders, for example but not limited to, hemaglobinapathy, thalassemia and aplastic anemia. In some embodiments, the oral pharmaceutical formulation comprising an S-isomer of α-methyl-hydrocinnamic acid can be used to increase red blood cell proliferation, or increase the proliferation of hemoglobin-expressing cells in a subject in need thereof, e.g., a subject having a blood deficiency such as a subject undergone chemotherapy or radiation exposure or radiation therapy. In some embodiments, a formulation comprising an S-isomer of alpha-methyl-hydrocinnamic acid (ST7S) can be used to simulate myelopiesis or erythropoiesis in a subject in need thereof. |
US09603812B2 |
Treatment of autistic spectrum disorder
A method for treating a patient having ASD is disclosed. The method includes administering to the patient a therapeutically effective amount of an alpha-2 adrenergic agonist in an extended release dosage form in combination with a therapeutically effective amount of inositol. |
US09603810B2 |
Nanoimprinting of silk fibroin structures for biomedical and biophotonic applications
The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based films with photonic nanometer scale patterns. In addition, the invention provides for processes by which the silk fibroin-based films can be nanoimprinted at room temperature, by locally decreasing the glass transition temperature of the silk film. Such nanoimprinting process increases high throughput and improves potential for incorporation of silk-based photonics into biomedical and other optical devices. |
US09603807B2 |
Enteral administration of sorbent polymer for treatment and prophylaxis of inflammation
The invention provides a method of ameliorating inflammation in a patient involving administering to the patient a therapeutically effective dose of composition including polystyrene divinyl benzene copolymer and a polyvinyl pyrrolidone polymer. More particularly, the method relates to using these polymers as an enteral sorbent preparation to remove inflammatory mediators, such as cytokines, from the intestinal lumen. The polymers can be in the form of a preparation of polystyrene divinyl benzene copolymer beads with a biocompatible polyvinyl pyrrolidone polymer coating. |
US09603806B2 |
Pharmaceutical compositions for the treatment of Helicobacter pylori
Single oral solid dosage form comprising an immediate release first dosage composition having at least two antibiotic agents and a delayed release second dosage composition having a proton pump inhibitor are provided herein. The single oral solid dosage form according to some aspects of the invention can be used for the treatment of disorders associated with infection by H. pylori or the prevention of recurrence of disorders associated with infection by H. pylori. |
US09603805B2 |
Easily dosable solid preparation
It has been desired to develop a coating composition, which is used for an orally-administered preparation having an improved administering property, and/or an easily administrable preparation that does not affect dissolution property. The present invention provides a coating composition comprising: a first thickener selected from the group consisting of a carboxyvinyl polymer and sodium alginate; a polyvalent metal compound; at least one type of a second thickener selected from the group consisting of xanthan gum, guar gum and sodium alginate, with the proviso that when the first thickener is sodium alginate the second thickener is not sodium alginate; and sucralose. |
US09603798B2 |
Antibody-conjugated double-emulsion nanocapsule and preparation methods thereof
An antibody-conjugated double-emulsion nanocapsule is provided. A linking group is introduced on the surface of a double-emulsion nanocapsule, which is composed of an oily shell enclosing an aqueous core, to link the double-emulsion nanocapsule with an antibody. |
US09603797B2 |
Oral and/or buccal composition in the form of a thin film of a weakly soluble active ingredient, method of preparing same and use of same
The present invention relates to an oral and/or buccal composition in the form of a thin film of a pharmaceutically active ingredient weakly soluble in water and gastro-intestinal tract fluids, comprising particles of said active ingredient dispersed in a film-forming polymer, at least 50% by weight of the total weight of the active ingredient having a particle size distribution such that at least 90% of said particles have a size below 1000 nm, preferably less than 800 nm, and even more preferably less than 600 nm, and to the method of preparing that composition and the use thereof. |
US09603795B2 |
Composite for preparing a transdermal delivery device and method for synthesizing the composite thereof
A composite for preparing a transdermal delivery device and a method for synthesizing the composite thereof comprising at least one polymer and at least one macrocyclic molecule, wherein the at least one polymer and the at least one macrocyclic molecule are adapted to form a complex. |
US09603794B2 |
Preparations of effervescent formulations comprising cephalosporin and uses thereof
The present invention relates to a process for preparing effervescent dosage forms comprising at least one antibiotic of cephalosporin group. The present invention also relates to effervescent formulations and preparations comprising antibiotics of second generation cephalosporin. |
US09603793B2 |
Nano / micro bubbles for drug delivery
The present invention provides a nano/micro bubble system for drug delivery comprising a gas core, a plurality of surfactants and an active ingredient. The surfactants surround the gas core and form a double-layer structure having an inner layer and outer layer. The active ingredient is embedded in a gap formed between the inner layer and the outer layer of the double-layer structure and comprises a nucleic acid, a peptide or a protein. |
US09603789B2 |
Composition containing a natural extract
Disclosed is a composition containing an active ingredient or ingredients comprising an extract or extracts of one or more constituents selected from the group consisting of Astragalus membranaceus, Saururus chinensis, Glycyrrhizae radix, rose, rhubarb, Acanthopanax senticosus and cortex Phellodendri. The composition is efficacious in suppressing acneiform pigment deposition and/or pitted scars, and can be used to advantage in various ways in the fields of cosmetics, foods and drugs. |
US09603788B2 |
Hair styling composition
An object of the present invention is to provide a hair styling composition formulated to make hair styling easy and to add wet-look shine to hair. The hair styling composition which achieves the above object contains (A) a thickener, (B) a hair fixative polymer and/or a liquid oil, (C) a wax particle dispersion, and (D) water. In the hair styling composition of the present invention, the wax particle dispersion (C) is preferably an Euphorbia Cerifera (Candelilla) wax particle dispersion or a beeswax particle dispersion, or preferably contains wax, at least one nonionic surfactant selected from the group consisting of polyoxyethylene cetyl ether and polyoxyethylene polyoxypropylene cetyl ether, and water. |
US09603787B2 |
Sunscreen formulations comprising Gemini surfactants and silicone based surfactants
A non-whitening sunscreen formulation for application to wet skin includes a surfactant system and organic UV absorbing materials where surfactant system includes a silicon based surfactant and a nonionic Gemini surfactant. Methods of making the sunscreen formulation are also included. |
US09603783B2 |
Three-phase cosmetic compositions comprising nacres
This invention relates to a cosmetic composition comprising a physiologically acceptable medium containing aqueous phase, an oily phase and nacre particles, constituted of a substrate partially or totally coated with one or more layers. |
US09603780B2 |
Dental composition
Dental composition comprising a water-soluble polymerizable compound of the following formula (1): wherein A is a linear or branched linker group represented by the following formula (3), wherein the nitrogen atom of at least two of the termini forms an amide bond with an X moiety; wherein R′ represents a hydrogen atom or a substituted or unsubstituted aliphatic or cycloaliphatic hydrocarbon group, wherein each R may be the same or different L1, L2, and L3 which may be the same or different, independently represent a single bond, or a C2-20 straight-chain, branched or cyclic hydrocarbon group optionally containing from 1 to 6 heteroatoms selected from nitrogen and oxygen in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from carboxylic acid groups or a salt thereof, hydroxyl groups, thiol groups and amino groups, and in case a plurality of L1 and L2 are present, each of L1 and L2 may be the same or different; Q1 and Q2, which may be the same or different, independently represent a single bond or a linkage selected from an amide, a urethane, a urea and a thiourea linkage; k is an integer of at least 0, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, wherein each X may be the same or different and are represented by the following formula (2): wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—COOM, wherein M represents a hydrogen atom or a metal atom, m is an integer of from 0 to 6, L is a bond or a C1-6 alkylene group; and n is an integer of at least 2; (ii) an initiator system; optionally a polyacidic polymer; optionally water and/or a water soluble solvent; and optionally a particulate filler. |
US09603779B2 |
Dental composite material having stable pasty property
A composite material including silanated filler and mixed polymerizable monomer, having a stable pasty property which keeps well and has a consistent usability. A composite material containing a silanated filler, a polymerizable monomer, and a polymerization initiator, and may be produced by a process which includes a mixed polymerizable monomer preparing step, a silanation step, a silanated filler preserving step, a composite material preparing step, a composite material preserving step, a composite material filling step, and a small quantity preserving container preserving step. |
US09603771B1 |
Chest compression device and linen attachment assembly for chest compression device
A chest compression device and a linen attachment assembly for a chest compression device are presented herein. In particular, the chest compression device is connectable to an air pulse generator for performing chest compression therapy or techniques while one or more chest panels are positioned in an overlying relation to the patient's chest. The device includes an attachment assembly disposed on opposite sides thereof and includes one or more connectors attached to the chest panel(s) and a separate grooved anchor. The grooved anchor is positioned under the linen on opposite sides of the patient, the connector attaches to the anchor through the linen, pinching the linen there between. |
US09603765B2 |
Telescoping and elevating femoral support
A system for manipulating the position and orientation of a patient's leg includes an extension rail configured to be coupled to an operating table or bed. In addition, the system includes an elongate support rail coupled to the extension rail and having a longitudinal axis. Further, the system includes a deck coupled to the support rail. The deck is configured to be moved axially relative to the support rail. |
US09603764B2 |
Method and apparatus for a locking caster
A lockable swivelable caster provides for an interaction between a centering element and a locking element to pivotally urge the locking element into a locking notch of the centering element such that the locking element is captured by the locking notch to prevent swiveling of the caster wheel. |
US09603758B1 |
In-floor vehicle ramp
A ramp system includes a base frame adapted to be mounted to a vehicle. First and second elongate track members are mounted to the base frame in generally parallel, spaced-apart relation so that they extend along a longitudinal direction. A trolley assembly is moveably mounted to the first and second elongate track members so that the trolley assembly is moveable along the longitudinal direction between retracted and extended positions. A ramp member is pivotally mounted to the trolley assembly. A support roller mounted to the base frame supports a portion of the ramp member. A handle assembly mounted to the ramp member allows a user to move the ramp member between the retracted and extended positions. |
US09603755B2 |
Absorbent article with klemm gradient and water repellent finishing
An absorbent member containing a hydrophobic material subjected to hydrophilic treatment, a plurality of through holes passing through the absorbent member in a thickness direction formed at a portion of the absorbent member in a target region (P). The absorbent member has a layer-stacked structure of a plurality of layers, stacked in the thickness direction. The Klemm water absorption height of a lower layer most proximal to the backsheet is higher than that of an upper layer most proximal to the topsheet. The backsheet contains a moisture permeable film including a plurality of microvoids, and having water repellent portions formed by water repellent finishing, on a portion in the target region (P) of a skin-facing surface of the moisture permeable film. A ratio of the total area of portions on which the water repellent finishing is performed to the area of the target region (P) is from 30% to 60%. |
US09603751B2 |
Methods for transferring discrete articles
A method of transferring discrete articles from or to a moving carrier member using a transfer assembly is provided. The transfer assembly includes a frame defining a rotation axis and a transfer member including a transfer surface configured to receive one of the discrete articles. The method includes rotating the transfer member about the rotation axis and maintaining a substantially constant pressure between the substantially flat transfer surface and the rotating carrier member throughout a zone of discrete article transfer. |
US09603749B2 |
Nasal drip pad
A nasal drip pad apparatus for use on a patient after sinus surgery including a drip pad assembly positioned underneath the patient's nose and a string forming a continuous loop configured to extend through the interior of the drip pad assembly configured to form a pair of loops. One of the loops is placed around one of the patient's ears and the other one of the loops is placed around the other one of the patient's ears. |
US09603747B2 |
Adhesive tape made of silicone intended for medical applications
An adhesive tape (1) made of silicone is intended for medical applications. The tape (1) has a sheet material (12) based on nonwoven fibers, coated on an internal face (12a) intended to be in contact with the skin, with a barrier membrane (14) which adheres to the sheet material, based on crosslinked silicone polymer, and with a layer (16) of atraumatic and biocompatible silicone adhesive gel, and on an external face (12b), with a layer (18) of a nonstick and waterproof polymer based on a fluorosilicone or fluorocarbon polymer. |
US09603745B2 |
Introducer for otolaryngological devices
Provided is an introducer for use with otolaryngological devices such as Eustachian tube stents. The introducer includes a guide, a stopper, an engager, and a release mechanism. An otolaryngological device having a first surface and a second surface that is nonparallel to the first surface may be loaded on the introducer by frictionally engaging the first surface of the device to a distal terminus of the engager. The device may be unloaded from the introducer by actuating the release mechanism. Upon actuation, the release mechanism slides the distal terminus of the engager toward the guide while the stopper abuts the second surface of the device. As a result, the relative motion between the engager and the stopper slides the device off the engager. Also provided are kits that include the introducer and methods for using the introducer. |
US09603744B2 |
Adaptable patient interface
Systems and methods are described for stabilizing an eye for an ocular laser procedure while minimizing corneal distortions which can adversely affect a surgical laser beam. For the systems, a patient interface includes a contact element for stabilizing the eye and establishing a conformal interface with the anterior surface of the cornea. More specifically, devices are disclosed which overlay both a central corneal region and a peripheral corneal region. In some embodiments, a first material is used in the contact element to overlay the central corneal region and a second material is used in the contact element to overlay the peripheral corneal region. Typically, the first and second materials differ in terms of hardness and deformability. In another embodiment disclosed herein, a contact element having a viscoelastic material for stabilizing an eye for a laser procedure is described. |
US09603742B2 |
Remote magnetic driven flow system
A system for implantation in an eye of a patient includes a flow device sized for implantation into the eye of the patient. The flow device includes a fluid flow passageway and a flow system. The flow system may include a regulator having a magnetic element, and may be displaceable in the fluid flow passageway to affect flow through the fluid flow passageway. The system may also include a control device physically separate from the flow device and configured to be disposed outside the eye, the control device comprising an actuator magnetic field generator configured to act on the magnetic element to adjust the regulator in the flow system to selectively adjust flow through the flow device in response to changes in intraocular pressure. |
US09603740B2 |
Device for vitrectomy surgical operations
A vitrectomy probe for removing vitreous material from an eyeball, having a longitudinal axis and an outer tube with a closed end and a lateral surface, at least one inlet port located proximate to the closed end and configured to allow the vitreous material to enter into the outer tube; an inner tube arranged in the outer tube to relatively move with respect to the outer tube, the inner tube having an opening with a cutting profile through which the vitreous material can be cut and can enter the inner tube. A drive unit configured for causing the outer tube and the inner tube to move relatively with respect to each other, in such a way that the cutting profile cuts the vitreous material entering the inlet port. |
US09603733B2 |
Highly flexible stent
A stent includes: wavy-line pattern bodies having a wavy-line pattern and arranged side-by-side in an axial direction; and coiled elements arranged between the wavy-line pattern bodies adjacent and extending in a spiral manner around an axis, in which all apices on opposite sides of the wavy-line pattern of the wavy-line pattern bodies that are adjacent are connected by way of the coiled element. When viewing in a radial direction, a circular direction-of the wavy-line pattern bodies is inclined with respect to the radial direction, and a winding direction of one of the coiled elements located at one side in the axial direction with respect to the wavy-line pattern bodies and a winding direction of one other of the coiled elements located at the other side in the axial direction are opposite. |
US09603728B2 |
Bioerodible magnesium alloy microstructures for endoprostheses
A bioerodible endoprosthesis includes a bioerodible magnesium alloy. The bioerodible magnesium alloy has a microstructure including equiaxed Mg-rich solid solution-phase grains having an average grain diameter of less than or equal to 5 microns and second-phase precipitates in grain boundaries between the equiaxed Mg-rich solid solution-phase grains. The beta-phase precipitates have an average longest dimension of 0.5 micron or less. The microstructure can be produced by one or more equal-channel high-strain processes. |
US09603726B2 |
Adjustable seal system, seal component and method for using the same
An adjustable seal system, seal component for use in the system, and method are provided for forming a sealing interface between a residual limb and a prosthetic socket. The seal component is selectively placed over the outer surface of a suspension liner including a plurality of seal bands, which the seal component may removably and securely engage. |
US09603724B2 |
Robust swing leg controller under large disturbances
Local swing leg control was developed that takes advantage of segment interactions to achieve robust leg placement under large disturbances while generating trajectories and joint torque patterns similar to those observed in human walking and running. The results suggest the identified control as a powerful alternative to existing swing leg controls in humanoid and rehabilitation robotics. Alternatively, a detailed neuromuscular model of the human swing leg was developed to embody the control with local muscle reflexes. The resulting reflex control robustly places the swing leg into a wide range of landing points observed in human walking and running, and it generates similar patterns of joint torques and muscle activations. The results suggest an alternative to existing swing leg controls in humanoid and rehabilitation robotics which does not require central processing. |
US09603722B2 |
Alignment guide
A surgical instrument alignment guide comprising a mount (2) arranged to be coupled to a bone of a patient, an alignment rod (4), a guide rod (24) and an indicator (26). The alignment rod (4) has a first end pivotally coupled to the mount (2) such that the inclination of the alignment rod (4) relative to the mount (2) is adjustable. The guide rod (24) is couplable to a second end of the alignment rod (4) at an adjustable angle and orientation such that the guide rod (24) can extend transverse to the alignment rod (4). The indicator (26) is coupled to the guide rod (24) to indicate when the guide rod (24) lies at a desired angle relative to a horizontal axis. Also disclosed is a method of aligning a surgical instrument using the surgical instrument alignment guide. |
US09603720B2 |
Osteotome guide configured to attach to an implanted femoral component
Guides configured to guide one or more osteotomes to remove a femoral component that is implanted in a femur. When implanted, the femoral component includes a stem implanted within the femur, a proximal end that extends from the femur, and a receptacle in the proximal end. The guides are configured to attach to the femoral component and attach to the receptacle in the femoral component. The guides include one or more openings sized to guide the osteotomes along the stem of the femoral component. The guides may further include multiple different sections that can be attached together. |
US09603718B2 |
Spacer with temporary fixation plate
A system for spinal fusion includes a spacer, a plate, an attachment member, and a first temporary fixation screw. The spacer includes a first coupling aperture having a first thread with a thread pitch that is greater than or equal to one third of a depth of the first coupling aperture. The plate includes a first attachment aperture and second coupling aperture. The attachment member includes a mating thread that mates with the first thread. The attachment member is configured to couple the spacer and the plate when inserted through the second coupling aperture and rotated to engage the first thread of the first coupling aperture. The first temporary fixation screw is configured to attach the plate to a first vertebra when inserted through the first attachment aperture and driven into the first vertebra. |
US09603711B2 |
Patient-adapted and improved articular implants, designs and related guide tools
Methods and devices are disclosed relating improved articular models, implant components, and related guide tools and procedures. In addition, methods and devices are disclosed relating articular models, implant components, and/or related guide tools and procedures that include one or more features derived from patient-data, for example, images of the patient's joint. The data can be used to create a model for analyzing a patient's joint and to devise and evaluate a course of corrective action. The data also can be used to create patient-adapted implant components and related tools and procedures. |
US09603710B2 |
Methods of manufacturing perforated osteochondral allograft compositions
Osteochondral graft composition that include a cartilage component and a bone component, and which include one or more perforations in the bone component and/or the cartilage component, are provided. Methods of manufacturing and using such osteochondral graft compositions are also provided. |
US09603708B2 |
Low crossing profile delivery catheter for cardiovascular prosthetic implant
A delivery catheter and a method for deploying a cardiovascular prosthetic implant using a minimally invasive procedure are disclosed. The delivery catheter comprises an elongate, flexible catheter body having a proximal end and a distal end, wherein the distal end has an outer diameter of 18 French or less, a cardiovascular prosthetic implant at the distal end of the catheter body, wherein the cardiovascular prosthetic implant comprises an inflatable cuff and a tissue valve coupled to the inflatable cuff, and at least one link between the catheter body and the cardiovascular prosthetic implant. |
US09603702B2 |
Intraocular lenses for managing glare, adhesion, and cell migration
An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens. The subsurface layer is configured to scatter an amount of light that is at least twice the amount of light scattered by portions of the material adjacent the subsurface layer or at least twice the amount of light scattered by another intraocular lens that does not have the subsurface layer, but which is otherwise substantially equivalent. |
US09603698B2 |
Biocompatible mesh implant
A mesh device for supporting one or a combination of a breast implant or breast tissue is provided formed of interlaced filaments forming a mesh structure which will not unravel when cut across a mid section of the mesh device. A titanium layer positioned on the exterior surface of the filaments of the mesh provide both a biocompatible interface with surrounding tissue and enhanced engagement of the filaments to prevent unraveling. |
US09603694B2 |
System and apparatus for adjustable gastric bypass
An apparatus for gastric bypass is disclosed. The apparatus for gastric bypass includes a primary passage having an input and an output. The apparatus also includes a bypass conduit, coupled to the primary passage, having an input and an output, wherein the passage input is interspersed with the conduit input. The apparatus further has a primary regulator coupled to the primary passage and adjustable to control a primary flow profile from the input to the output of the primary passage. The apparatus also has a bypass regulator coupled to the bypass conduit and adjustable to control a bypass flow profile from the input to the output of the bypass conduit. |
US09603692B2 |
Embolic filters with controlled pore size
A device for filtering emboli from blood flowing through a lumen defined by the walls of a vessel in a patient's body. The device has a filter element being expandable from a collapsed configuration to an expanded configuration. The filter element includes a material having pores, and the material having pores includes cylindrical wires having at least three different diameters arranged in a pattern of graduated diameters. |
US09603690B1 |
Container for dental appliances
A container for a dental appliance. The container includes a first compartment with at least one first wall, a first enclosing portion, and a separation plate. The first compartment includes a length, a width, and a height to accept a first dental appliance and indicated by a first indicator. The container includes a second compartment defined by at least one second wall, a second enclosing portion, and the separation plate. The second compartment includes a second length, second width and second height to accept a second dental appliance and indicated by a second indicator. The container includes a moveable and closeable door which opens to permit access to at least one of the first compartment and the second compartment. The dental appliance in the first compartment is separate from the dental appliance in the second compartment by the separation plate, and the container comprises ports to allow circulation. |
US09603689B2 |
Electronic toothbrush
A toothbrush is provided. The toothbrush includes an elongated shaft having a brushing head removably attached thereon configured to extend and retract the brushing head from a handle portion. The handle portion is configured to support the brushing head, a rotating assembly, and an antimicrobial assembly. The rotating assembly is configured to rotatably drive the brushing head in either clockwise rotation or counterclockwise rotation. The antimicrobial assembly is configured to sterilize the brushing head and the elongated shaft shaft when retracted within the handle portion. The handle portion further includes a control panel on an exterior face of the handle portion configured to allow a user to operate the rotating assembly and/or the antimicrobial assembly. In this way, the toothbrush allows a user to achieve optimal cleaning of his teeth without introducing harmful microorganisms into his oral cavity. |
US09603688B2 |
Pre-charged prophy angle
A pre-charged prophy angle having a (a) housing that includes a paste chamber, a rotatable head, a drive shaft, and a tube defining in part the paste chamber, the housing and paste chamber configured such that paste within the paste chamber can be dispensed without contacting the drive shaft; (b) a cup secured to the rotatable head, and (c) a paste dispensing assembly having a plunger movably secured to a push rod configured to reciprocally move linearly within the housing, the plunger including a clip for gripping the push rod such that linear movement of the push rod in a first direction causes the plunger to move in the first direction, while the clip precludes movement of the plunger in a second direction when the push rod in directed in the second direction. |
US09603687B2 |
Oral care implement
Provided is an oral care implement (1), comprising: a body (100); a carrier (130) connected to the body (100) and movable relative to the body (100), the carrier carrying one or more cleaning elements (134); a carrier drive mechanism (200) operable to drive movement of the carrier (130) relative to the body (100); an auxiliary device (400); and an auxiliary device drive mechanism (600) that is selectively engagable with the carrier drive mechanism (200) during operation of the carrier drive mechanism, so as to selectively operate the auxiliary device (400) during movement of the carrier (130) relative to the body (100). Also provided is a method of operating the oral care implement (1), and a kit of parts for an oral care implement. |
US09603686B2 |
Oral hygiene implement
The present disclosure is concerned with an oral hygiene implement having a neck section extending along a longitudinal direction and having a neck section housing surrounding a neck section cavity, a head section having a through hole therein extending through the head section along a through hole direction having an angle with respect to the longitudinal direction and having a head section housing surrounding the through hole, wherein the through hole defines a first and a second opening in the head section housing, and wherein a cap element separately made from the head section housing is connected with the head section housing to essentially cover the first opening and a carrier element separately made from the head section housing is arranged to cover the second opening. |
US09603675B2 |
Medical or dental handpiece
Embodiments of a medical or dental handpiece are disclosed. A medical or dental handpiece may include a rotatable drive element to drive a tool that can be connected to the handpiece, a rotational speed measuring device which is designed to generate a variable electric rotational speed measurement signal assigned to the rotational speed of the drive element, a lighting device that can be supplied with electric power for emitting radiation, in particular visible light, onto a treatment site, and at least one shared electric line, which is provided for transmitting electric power to the illumination device and the rotational speed measurement signal of the rotational speed measurement device. Further a corresponding method for the operation of a medical or dental handpiece is disclosed. |
US09603672B2 |
Mechanized multi-instrument surgical system
A surgical system includes an instrument driver having a distal end positionable in a body cavity and a user input device. The instrument driver and user input device are positioned to removably receive distal and proximal portions, respectively, of a surgical instrument. The user input device is configured to generate movement signals in response to manual manipulation of the proximal portion of the surgical instrument. At least one motor operable to actuate the instrument driver in response to the movement signals and to thereby change position of the distal portion of the surgical instrument within the body cavity. |
US09603670B2 |
Method for designing and/or optimizing a surgical device
A method for designing and/or optimizing an implant that has one or more through holes with a central axis for receiving a bone fixation element. The method includes: providing a general collection of three-dimensional bone quality data obtained from a patient population; identifying in the patient population N>2 categories of patients with significantly different N>2 homologous sub-collections of bone quality data; and designing an implant or optimizing an existing implant for each of the N>2 sub-collections such that the at least one through hole is located at an optimal place and with an optimal direction of the central axis relative to the implant. The optimal position and direction is chosen based on each of the N>2 sub-collections of data so as to obtain an optimal anchorage of the bone fixation element in the bone when introduced through the through hole. |
US09603654B2 |
Multi-layer electrode ablation probe and related methods
Electric field delivery and ablation of target tissue regions, including cancerous cells and solid tumors. Methods and systems include delivering an electric field to a target tissue, and may include positioning a first electrode or plurality to at least partially define a first treatment volume in the target tissue; positioning a second electrode or plurality to at least partially define a second treatment volume, the first volume is disposed in the second volume; and establishing a first current flow extending through the first volume and a second current flow extending through the second volume. |
US09603653B2 |
Apparatus for coagulating tissue
For the coagulation of tissue there are known instruments, in particular probes, that are designed to deliver argon gas into a space between an electrode within the probe and the tissue. In some cases the intention is to coagulate tissues situated at the side of the outlet of the probe. The invention provides an apparatus for coagulating tissue in which the distal end of the electrode projects out of the gas-delivering device or probe, and at said distal end a guiding device for directing and guiding the gas or plasma is disposed in such a way that at least part of the flowing gas or plasma is deflected into a predetermined direction. |
US09603652B2 |
Electrosurgical instrument including a sensor
An electrosurgical system includes an electrosurgical generator, an electrosurgical instrument, an optical clarity sensor and a control component. The electrosurgical generator generates electrosurgical energy for use during electrosurgery. The electrosurgical instrument is coupled to the electrosurgical generator and treats tissue. The optical clarity sensor is coupled to the electrosurgical generator and is adapted to measure tissue with at least two optical frequencies. The control component is operatively coupled to the optical clarity sensor and receives sensor data therefrom. The control component communicates control instructions to the electrosurgical generator to control the generation of the electrosurgical energy. |
US09603650B2 |
Cryogenic treatment systems
Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session. |
US09603645B2 |
Cement-directing orthopedic implants
A cement-directing structure for use in cement-injection bone therapy includes a collapsible, self-restoring braided structure with regions of differential permeability to the bone cement. The regions of differential permeability may be provided by areas where the braided mesh density is greater or lesser than surrounding areas and/or by means of a baffle. After the structure is placed in a void within a bony structure, cement is injected into the interior of the structure then oozes out in preferred directions according to the locations of the regions of differential permeability. |
US09603640B2 |
Lower extremity fusion devices and methods
A fusion implant and fusion members for fusing target fusion bones of a lower extremity. The fusion implant including internally threaded apertures of a first thread lead, and fusion members including threading of the first thread lead and threading of a second thread lead that is less than the first thread lead. The fusion implant and a targeting instrument being configured to couple to one another in a predefined orientation. The predetermined orientation resulting in alignment of aspects of the fusion implant with aspects of the targeting instrument. The targeting instrument providing both distraction and compression to the joint between the target fusion bones. A guide instrument for preparing one of the target fusion bones for fusion thereof. A surgical method for applying compression to the joint between the target fusion bones to facilitate fusion thereof utilizing a fusion implant, fusion members, a targeting instrument and a guide instrument. |
US09603634B1 |
Percutaneous rod-to-rod cross connector
A percutaneous cross connector system for use with implantation rods comprising a rod attachment device comprising a first jaw portion and a second jaw portion. The first jaw portion comprises a first concave surface to engage with a surface of a rod, a first biasing member, and a first pivoting mechanism. The second jaw portion comprises a second concave surface to engage with an opposite surface of the rod from the first jaw portion, a second pivoting mechanism, a second biasing surface, and a second locking surface. The first and second jaw portions can be mated so that the first and second concave surfaces are positioned on opposite sides of the rod, the first and second pivoting mechanisms are aligned to pivot on a common axis, and the first biasing member is engaged against the second biasing surface to drive the second jaw portion against the rod. |
US09603633B2 |
Interspinous spacer devices for dynamic stabilization of degraded spinal segments
An interspinous spacer device for the treatment of high-grade spinal disorders is disclosed herein. The interspinous spacer device includes a sliding rod and a base that contains a curved internal track that limits the range of motion and center of rotation of the spinal segments stabilized using the device to the physiological levels of a nondegraded spinal segment. |
US09603631B2 |
Spinal stabilization systems and methods
A spinal stabilization system may be formed in a patient. In some embodiments, a minimally invasive procedure may be used to form a spinal stabilization system in a patient Bone fastener assemblies may be coupled to vertebrae Each bone fastener assembly may include a bone fastener and a collar. The collar may be rotated and/or angulated relative to the bone fastener. Detachable members may be coupled to the collar to allow for formation of the spinal stabilization system through a small skin incision. The detachable members may allow for alignment of the collars to facilitate insertion of an elongated member in the collars. An elongated member may be positioned in the collars and a closure member may be used to secure the elongated member to the collars. |
US09603625B2 |
Internal joint stabilizer device, system and method of use
A stabilization device is provided including an axle and a portion that can be affixed to a bone. The device is used to stabilize a joint while allowing motion of the joint along its natural trajectory and it is placed internally in order to prevent pin tract problems. Additionally, methods for using the device are provided that include, in various sequences, inserting the axle into a bone of a joint, adjusting the geometry of the device and attaching the fixable portion to another bone of the joint. The device can be provided as part of a system including an axis trajectory guide useful for locating the axis of rotation of the joint prior to insertion, adjustment and attachment of the device. |
US09603624B2 |
System for myomectomy and morcellation
A method for dissecting a myoma from a uterine wall includes inserting a myomectomy screw retractor into a surgical site, articulating a tool assembly positioned at a distal end of the myomectomy screw retractor such that a screw of the tool assembly is positioned adjacent to the myoma orthogonal to the uterine wall, rotating the screw of the tool assembly into the myoma until the screw is substantially engaged with the myoma, manipulating the myoma by pitching, rotating, and/or providing traction to the myoma to expose cutting planes, and dissecting the myoma from the uterine wall by cutting along the exposed cutting planes. |
US09603618B2 |
Medical device for removing an implanted object
Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the surgical device includes a handle, an elongate sheath and a circular cutting blade that extends from the distal end of the sheath upon actuating the handle. The circular cutting blade is configured to engage the tissue surrounding an implanted lead and cut such tissue in a coring fashion as the surgical device translates along the length of the lead, thereby allowing the lead, as well as any tissue remaining attached to the lead, to enter the device's elongate shaft. The surgical device has a barrel cam cylinder in the handle assembly that imparts rotation of the blade and a separate cam mechanism in the tip of outer sheath assembly that imparts and controls the extension and retraction of the blade. The barrel cam cylinder and cam mechanism cooperate to cause the blade to rotate in a first direction and extend from and retract in the outer sheath due to a first actuation of the handle and to rotate in a second direction and extend and retract in the outer sheath due to a second actuation of the handle. |
US09603611B2 |
Interbody spacer and plate inserter and methods of use
An attachment guide for an interbody cage and a spinal plate includes a guide body and a coupling element. The guide body includes a proximal end, a pair of flanges, and a distal end. The proximal end includes an inserter attachment element configured to removably receive an inserter instrument. The pair of flanges extends from the guide body and is configured to engage the spinal plate. The distal end includes a surface configured to contact an anterior surface of the interbody cage and a cage engagement element configured to extend distally from the surface and into a wall of the interbody cage. The coupling element extends through an aperture of the guide body from the proximal end to the distal end and is configured to draw the pair of flanges into greater contact with the spinal plate and the cage engagement element into greater contact with the interbody cage. |
US09603610B2 |
Tools and methods for tissue removal
The present invention is directed to material removal instrument for forming cavities in interior body regions, particularly cavities in intervertebral discs and vertebrae. The instrument includes a cannula and a rotation mechanism disposed at least partially within the cannula. A cutting element extends from the rotation mechanism and impacts and dislocates tissue as the rotation mechanism is rotated within the body. Dislocated tissue with withdrawn from the body via the cannula. |
US09603605B2 |
High tibial osteotomy guide
A cutting block for use in a bone osteotomy procedure is disclosed, and includes a first cutting guide surface, a second cutting guide surface, and a third cutting guide surface. The first, second, and third cutting guide surfaces are adapted to be temporarily affixed to a bone having a first side and a second side such that the first cutting guide surface is disposed on the first side of the bone, and such that the second cutting guide surface and third cutting guide surface are disposed on the second side of the bone forming an angle therebetween. |
US09603604B2 |
Orthopaedic cutting block
A bone cutting block includes: a plurality of saw slot plates each including a plurality of ends opposing one another, each of the plurality of ends including a locating feature, the plurality of saw slot plates defining at least one slot therebetween which is configured for receiving a bone saw blade therethrough to make a predefined cut in a bone; and two side plates opposing one another, including a plurality of locating features, and supporting the plurality of saw slot plates, each locating feature of the plurality of saw slot plates being connected with a respective one of the plurality of locating features of the side plates. |
US09603602B2 |
Uterine compression devices and methods
Disclosed are devices for reducing postpartum hemorrhage, including a belt having a fastener for securing the belt around a patient's body, a bladder being inflatable with air and adapted to be placed over the patient's abdomen for applying selective external pressure to the patient's uterus, a manual pump operably connected to the bladder to change air pressure of the bladder, and a pressure gauge for indicating the air pressure. Methods for using the devices are also disclosed. |
US09603601B2 |
Occlusion devices including dual balloons and related methods
An occlusion device may comprise a first tube having a first balloon positioned at a distal end, and a second tube having a second balloon positioned at a distal end. The first balloon may be sized and configured to occlude a vascular lumen upstream of a vascular puncture, and the second balloon may be sized and configured to simultaneously occlude the vascular lumen downstream of the vascular puncture. A method of occluding a vascular puncture may comprise positioning a distal end of an occlusion device comprising a first balloon and a second balloon through the vascular puncture and into a vascular lumen. The first balloon may be positioned downstream of the vascular puncture, and the second balloon may be positioning upstream of the vascular puncture. |
US09603600B2 |
Actuator for deployable implant
Systems and methods are provided for using an actuator to deploy an implant configured to close a tissue puncture or a natural opening in a body. The actuator includes a handle that is rotated in a first direction to deploy a first set of deployable wings of the implant, and that is rotated in a second, opposite direction to deploy a second set of deployable wings of the implant. A guide wire coupled between the implant and the actuator rotates and/or moves axially with the actuator to cause the wings to deploy. After each of the first and second rotation strokes, the handle is prevented from rotating beyond the first and second strokes, respectively. After the wings are deployed to engage tissue therebetween, the handle is operated to eject the implant from the actuator. |
US09603598B2 |
Surgical stapling device with a curved end effector
In various embodiments, an end effector for use with a surgical instrument is disclosed. The end effector comprises a first jaw and a second jaw moveable relative to the first jaw, wherein one of the first jaw and the second jaw comprises a plurality of staple cavities arranged in a plurality of curved staple cavity rows, and wherein at least one curved staple cavity row extends along a path. The path comprises a first curved portion comprising a first longitudinal vector component and a second curved portion comprising a second longitudinal vector component, wherein the second longitudinal vector component is opposite of the first longitudinal vector component. The end effector further comprises a firing member comprising a laterally-offset cutting edge, a first camming surface configured to engage the first jaw, and a second camming surface configured to engage the second jaw. |
US09603596B2 |
Systems and methods for closing a tissue opening
Tissue closure devices include one or more closure components, each closure component having a first member and a second member, each of the first and second members having a first surface that adheres to a tissue surface proximate to the tissue opening, each of the first and second members having a second surface substantially orthogonal to the first surface, and each of the first and second members having a transitional region between the first surface and the second surface which is contoured to evert an edge of the tissue opening upon the drawing together of the first and second members. |
US09603586B2 |
Methods and devices for cutting and collecting soft tissue
Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue. |
US09603584B2 |
Systems and methods for intravascular imaging with rotational transducers for concurrently imaging blood flow and tissue
A method for generating a composite image using an intravascular imaging device includes receiving reflected echo signals from at least one transducer along a first of a plurality of radial scan lines. The received echo signals are passed through a plurality of signal processing channels to form a plurality of filtered signals. The filtered signals include a high-resolution tissue structure signal and at least one first pre-blood-flow-mask signal. High-resolution tissue structure signals are processed to form a high-resolution tissue structural image. First pre-blood-flow-mask signals are cross-correlated with second pre-blood-flow-mask signals from an adjacent radial scan line to form blood-flow-mask signals. Blood-flow-mask signals are processed to form a blood-flow mask. For each pixel of the composite image, it is determined whether to use a corresponding pixel of the high-resolution tissue structural image or a corresponding pixel of the cross-correlated blood flow mask to generate the composite image pixel. |
US09603579B2 |
Three-dimensional (3D) ultrasound system for scanning object inside human body and method for operating 3D ultrasound system
Provided is a three-dimensional (3D) ultrasound system and a 3D ultrasound system operating method that may obtain 3D ultrasound data with respect to an object inside a human body to determine an accurate sagittal view. The 3D ultrasound system may include a scanner to generate ultrasound data including image data generated by scanning an object inside a human body, a processing unit to detect a center point of the object from the generated ultrasound data, and to generate, on the ultrasound data, a virtual plane on which the detected center point is placed, and a controller to rotate the ultrasound data based on the image data included in the virtual plane and to determine a sagittal view with respect to the object. |
US09603578B2 |
Method and apparatus for graphical assistance in a medical procedure
In a method and apparatus for graphical assistance in an interventional procedure to open an occlusion of a hollow organ of a patient a three-dimensional CT image data set of an examination region with the at least one hollow organ having the occlusion is retrieved and visualized segmentation data with segmentation data of the hollow organ at a display unit. At least two x-ray fluoroscopy images are acquired at different angulations the CT image data set is registered with at least two of the x-ray images. A number of fluoroscopy x-ray images are acquired during a time period, with real-time visualization of at least one x-ray fluoroscopy image and data of the CT image data set at the display unit. The steps are implemented individually and in sequence, and control options relating exclusively to the current step can be selected manually via a user interface depending on the step that is currently implemented, and only user inputs that are appropriate for the current step are accepted. |
US09603573B2 |
Detection of EMG activity using sensors on both sides of the body
A monitoring system may include each of a left and a right side EMG detection device and may be configured to detect either seizure activity associated with the left side or right side of a patient's body. The system may further be configured to differentiate symmetric or asymmetric seizure activity. For example, the system may characterize whether left and right side EMG detectors show similar or dissimilar levels of activation during a suspected seizure. In some embodiments, the system may also include one or more orientation and/or position sensors. The system may be configured to determine the orientation and position of the sensor over time and to correlate this data with EMG signals. |
US09603572B2 |
Analysis device with user-friendly menu controls
An analysis device is proposed for detecting an analyte in a liquid sample, in particular for detecting glucose in a bodily fluid. The analysis device comprises at least one control element, which is configured to provide a function menu with at least two menu items. The analysis device further comprises at least one adjustable selector element, in particular a mechanically adjustable selector element, which can be adjusted by a user to at least two different selection positions. The selector element is configured to remain in the adjusted selection position after being adjusted. The control element is configured to select a menu item corresponding to the adjusted selection position. The analysis device further comprises at least one operating element. At least one parameter in the selected menu item can be influenced by the user via the operating element. |
US09603570B2 |
Intravascular devices, systems, and methods having a sensing element embedded in adhesive
Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular devices are guide wires that include a distal sensing element mounted partially within a housing and embedded and/or surrounded by a flexible adhesive. For example, in some implementations a sensing guide wire includes a flexible elongate member; a housing coupled to the flexible elongate member; a flexible element extending distally from the housing; and a sensing element coupled to the flexible elongate member such that a proximal portion of the sensing element is positioned within the housing and a distal portion of the sensing element is positioned within the flexible element. A flexible adhesive can embed or surround the distal portion of the sensing element positioned within the flexible element. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided. |
US09603569B2 |
Positioning a wearable device for data collection
Wearable devices are described herein including at least two photodetectors and a mount configured to mount the at least two photodetectors to an external surface of a wearer. The at least two photodetectors are configured to detect alignment between the wearable device and a target on or in the body of the wearer (e.g., to detect the location of vasculature within the body of the wearer relative to the at least two photodetectors). Alignment of the at least two photodetectors relative to the target could enable detection of one or more physiological properties of the wearer. For example, the wearable device could include a sensor configured to detect a property of the target when the sensor is above the target, and alignment of the target relative to the at least two photodetectors could include the sensor being located above the target. |
US09603565B2 |
Single patient use depth gauge
A device for guiding a depth gauge for measuring blind holes formed through a bone including (a) a handle having an elongated body, an upper surface of the body having a peg extending therefrom to removably engage a proximal end of a first elongated rod of the depth gauge, the handle including a first slot extending into the upper surface and open to a first elongated channel extending through the handle and (b) a first elongated shaft extending through the first elongated channel and including a first tab extending through the first slot, a range of movement of the first elongated shaft relative to the handle being limited by engagement of the first tab with walls of the first slot. In an operative configuration, the slotted tab receives a proximal end of the depth gauge to control movement of an increased diameter insert at a distal end thereof. |
US09603562B2 |
Autonomous, ambulatory analyte monitor or drug delivery device
The invention relates to analyte monitoring/drug delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The invention can optionally provide for calibration without intervention of the user and can also provide for semi-continuous monitoring for day and night time. The invention can provide up to four, or more, weeks of operation. The invention can provide for a device that is relatively small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents. |
US09603556B2 |
Device and method for continuous biometric recognition based on electrocardiographic signals
Signal measurement for biometric recognition purpose includes a computational unit and a sensory unit designed to measure electrocardiographic (ECG) signals in a continuous fashion, guaranteeing that the biometric recognition is performed in an uninterrupted way whenever the device is used, with the purpose of enabling the automated recognition or validation of the identity of its wearer. The sensory unit has an electronic module through which the ECG is acquired. Its operating principle can be based in the electrical conductivity, in which case it requires contact with the skin of the user, or in any kind of capacitive or mechanical element, in which case it does not require any direct contact with the user. The device can be used in alternative or as a complement to existing systems that only perform a momentary identity check. It can be applied to vehicles, tablet computers or analogous contexts. |
US09603554B2 |
Systems, methods, and media for monitoring the condition of a patient's heart
Receiving a plurality of images of a first wall of the patient's heart, the plurality including a first image captured at a time ij and a second image captured at a time t2, determining, based on the plurality of images, a first characteristic of movement of at least a wall portion of the first wall during a time period spanning time t1 and time t2, the first characteristic of movement being determined by using one or more image processing techniques, and the first, characteristic of movement being based on at least one of: (i) a shape of the wall portion in the first image and a shape of the wall portion in the second image, and (ii) a location of the wall portion in the first image and a location of the wall portion in the second image: and outputting an indication of the first characteristic of movement. |
US09603553B2 |
Methods of measuring heart valve annuluses for valve replacement
A device for measuring an expanded internal orifice of a patient includes an orifice-expanding device, a pressure measuring device, and a size-measuring device. The size-measuring device measures a dimension of the orifice after it has been expanded by the orifice-expanding device. |
US09603551B2 |
Inductive respiration sensor
An inductive respiration sensor (10) comprises an inductive transducer (12) and sensing circuitry. The sensing circuitry comprises a transimpedance amplifier, TIA, (14), the sense input (16) of which is operatively connected to the inductive transducer. The TIA is configured to drive a current from its output (20) into the sense input such that the voltage on the sense input follows the voltage applied to the reference input (18) and to cause a voltage on the output indicative of the current. The TIA comprises a first (34) and a second (30) transistor. The collector or drain and the emitter or source of the first transistor are operatively connected between the sense input and the output of the TIA. The emitter or source of the second transistor is connected to the reference input, the collector or drain of the second transistor is connected to the base or gate of the first transistor, and the base or gate of the second transistor is connected to the sense input. |
US09603549B2 |
Implantable device with post-MRI cardiac signal sensing adjustment
An implantable device, such as a pacer, defibrillator, or other cardiac rhythm management device, can include an automatic testing and adjusting of cardiac signal sensing after an MRI scanning procedure, such as to accommodate an MRI-induced physiological change in sensed cardiac depolarization amplitude or in lead impedance such as at an electrode/tissue interface. |
US09603548B2 |
System and method for magnetic position tracking
An improved system for magnetic position tracking of a device includes a magnetic transmitter, a magnetic sensor, a computing system and a polarity inverter. The magnetic transmitter includes at least one transmitter coil that outputs a transmitted magnetic field having a time derivative component. The magnetic sensor includes at least one sensor coil that has coil terminals having a polarity, and the sensor coil is responsive to the time derivative component of the transmitted magnetic field and outputs a sensor signal. The computing system computes position and angular orientation data of a device based on the sensor signal and the polarity inverter is configured to connect to the coil terminals and to cause the polarity of the coil terminals to be reversed according to a switching signal. |
US09603544B2 |
Method of determining state variables and changes in state variables
The present invention relates to a method of determining physical, chemical and/or biological state variables, particularly substance concentrations, temperature, pH and/or physical fields, and/or the change in these state variables in an examination area of an examination object by determining the change in the spatial distribution of magnetic particles in this examination area as a function of the effect of influencing variables on at least a partarea and/or in the conditions in at least a part-area of the examination area, by means of the following steps: a) introducing magnetic particles into at least part of the examination area in a first state in which in the examination area or in parts thereof at least some of the magnetic particles that are to be examined are agglomerated and/or coupled to one another in pairs or more, or introducing magnetic particles into at least part of the examination area in a second state in which the particles are deagglomerated and/or decoupled and can be agglomerated and/or coupled, b) generating a magnetic field with a spatial profile of the magnetic field strength such that there is produced in the examination area a first part-area having a low magnetic field strength and a second part-area having a higher magnetic field strength, c) changing the, in particular relative, spatial position of the two part-areas in the examination area or changing the magnetic field strength in the first part-area so that the magnetization of the particles is locally changed, d) detecting signals that depend on the magnetization in the examination area that is influenced by this change, and e) evaluating the signals so as to obtain information about the change in the spatial distribution of the magnetic particles and/or about physical, chemical and/or biological state variables or the change therein in the examination area. The invention further relates to magnetic particle compositions, in particular functionalized magnetic particle compositions and their use in a method according to the invention. The invention further also relates to an apparatus for the measurement of state variables in the examination area. |
US09603542B2 |
Electro-physiological measurement with reduced motion artifacts
An apparatus and method (4,5,6,7,2) for capacitive measurement of electrophysiological signals (1) suppresses or reduces motion artifacts by providing a feedback mechanism. An average voltage between a capacitive sensor electrode (1) and the body (3) is controlled so as to reduce or minimize motion-induced signals. |
US09603541B2 |
Bio-medical electrode
The invention relates to a bio-medical electrode (100). In a preferred embodiment, an electrode interface comprises a top part (10) with an aperture and a bottom part (20). The bottom part (20) has a head portion designed for a fixation in said aperture and a flexible flange that clamps electrode sheets (31,32) in the connected state of the electrode interface such that the contact force between top and bottom parts is approximately constant during lifetime of the electrode interface. The top part (10) may preferably have the shape of a disk of magnetic or magnetizable material. The bottom part (20) may preferably be made from a conductive plastic such as ABS. The electrode interface may particularly be used in a TENS device. |
US09603537B2 |
Unit, assembly, device and method for testing a sensor means provided in a medical localisation device
A unit, assembly and device suitable for a medical localization device suitable for localizing a region in a body with a distal hollow needle includes a tube extending from a proximal first end to a distal second end. The first end is designed to be in communication with a fluid filled container. The unit includes a first part of sensor means. The first part is a sensor interface, in which the sensor interface is provided to the tube between the first end and the second end. The sensor interface is suitable for observation of the pressure in a fluid in the tube that is in communication with the fluid in the container. The unit includes a closing device distally with respect to the sensor interface for varying the pressure in the fluid in the tube, in which the sensor interface is a membrane. |