Document Document Title
US09290771B2 Recombinant microorganism having an enhanced ability to produce putrescine and a method for producing putrescine using the same
The present invention relates to a recombinant microorganism having enhanced ability to produce putrescine at high yield, wherein the activity of NCg10101 is weakened in a microorganism of genus Corynebacterium that has been modified to produce putrescine, and a method for producing putrescine using the same.
US09290768B2 Engineered microorganisms having resistance to ionic liquids
The present invention provides for a method of genetically modifying microorganisms to enhance resistance to ionic liquids, host cells genetically modified in accordance with the methods, and methods of using the host cells in a reaction comprising biomass that has been pretreated with ionic liquids.
US09290767B2 Oligonucleotides for modulation of target RNA activity
The present invention relates to oligonucleotides for modulation of target RNA activity. Thus, the invention provides oligonucleotides that bind to microRNA binding sites of target RNA. The oligonucleotides may activate RNase H or RNAi. In a preferred embodiment, the oligonucleotides prevents a micro RNA from binding to its binding site of the target RNA and thereby prevent the microRNA from regulating the target RNA. Such oligonucleotides have uses in research and development of new therapeutics.
US09290764B2 RNAi for the control of insects and arachnids
The present invention describes a new non-compound based approach for insect and/or arachnid control. The present inventors have identified for the first time novel targets for RNAi, which can effectively control insect and/or arachnid pest populations. Accordingly, the invention provides both nucleotide and amino acid sequences for the novel targets. Also provided are RNA constructs including double stranded RNA regions for mediating RNAi in insects, DNA constructs, expression vectors, host cells and compositions for controlling insects and/or arachnids using RNAi. Finally, the invention also provides for the use of the constructs, vectors, host cells and compositions in control of insects and/or arachnids populations and suitable kits for use in an RNAi based method of controlling insect and/or arachnid pests.
US09290761B2 MicroRNA inhibition for the treatment of inflammation and myeloproliferative disorders
The present disclosure relates to the finding that microRNA-155 plays a role in inflammation, hematopoiesis and myeloproliferation, and that dysregulation of microRNA-155 expression is associated with particular myeloproliferative disorders. Disclosed herein are methods and compositions for diagnosing an treating disorders, including inflammation and myeloproliferation, modulating the levels of expression of one or more genes selected from the group consisting of Cutl1, Arntl, Picalm, Jarid2, PU.1, Csflr, HIF1α, Sla, Cepbβ, and Bach1, and the like.
US09290759B2 Optimized miRNA constructs
The invention provides optimized miRNA sequences and their therapeutic use. The invention provides optimized miRNA constructs for treatment of neurodegenerative diseases.
US09290758B2 Potent anti APOB antisense compounds
The present invention relates to oligomer compounds (oligomers), which target APO-B100 mRNA in a cell, leading to reduced expression of APO-B100. Reduction of APO-B100 expression is beneficial for the treatment of certain medical disorders, such as diseases associated with apolipoproteinB activity, such as in non-limiting example, different types of HDL/LDL cholesterol imbalance; dyslipidemias, e.g., familial combined dyslipidemia (FCHL), acquired hyperlipidemia, hypercholesterolemia, statin-resistant hypercholesterolemia; coronary artery disease (CAD), coronary heart disease (CHD), atherosclerosis.
US09290756B2 Apparatus and methods for high throughput network electrophysiology and cellular analysis
Provided herein are apparatus and methods relating to the development of instrumentation for high throughput network electrophysiology and cellular analysis. More specifically, provided herein are multiwell microelectrode arrays (MEAs) and methods for the development of such an apparatus in an inexpensive fashion with a flexible, ANSI/SBS-compliant (American National Standards Institute/Society for Biomolecular Screening) format. Microelectrode arrays are a grid of tightly spaced microelectrodes useful for stimulating and sensing electrically active cells, networks and tissue. The techniques described herein relate to the use of microfabrication in combination with certain large-area processes that have been employed to achieve multiwell MEAs in ANSI/SBS-compliant culture well formats, which are also transparent for inverted/backside microscopy compatibility. These multiwell MEAs can be used to investigate two and three-dimensional networks of electrically active cells and tissue such as cardiac, neural, and muscular in a high throughput fashion. Also being ANSI/SBS-compliant, they are compatible with machinery and robotics developed for the pharmaceutical industry for drug screening applications.
US09290754B2 Beta-lactamases with improved properties for therapy
This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (GI tract) disorders such as C. difficile infection (CDI).
US09290749B2 Thioesterases and cells for production of tailored oils
The invention features plant acyl-ACP thioesterase genes of the FatB class and proteins encoded by these genes. The genes are useful for constructing recombinant host cells having altered fatty acid profiles. Oleaginous microalga host cells with the new genes or previously identified FatB genes are disclosed. The microalgae cells produce triglycerides with useful fatty acid profiles.
US09290744B2 SRPX for treatment of cancer
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an SRPX.
US09290738B2 Methods of decellularizing bone
The invention provides methods for decellularizing bone, e.g., human bone.
US09290735B2 Mammary gland epithelial cell culture
To provide a cell culture method capable of sustaining in-vivo functions for a long time by suppressing dedifferentiation. A cell culture method in accordance with the present invention is to culture cells in a multi-layered state in a minute partitioned space and to obtain a tissue structure having a function resembling an in-vivo function. When the cells are mammary gland epithelial cells, a hollow acinus-like structure can be formed. The minute partitioned space is particularly preferably a micro container in a cell culture container having a plurality of such micro containers on the surface.
US09290734B2 Process and composition for production of organic products
The present invention comprises a process to produce organic products from a single-carbon substrate; microbial compositions used in the process; and a process to isolate microorganisms for the process.
US09290727B2 Water-soluble pouch coated with a composition comprising silica flow aid
Water-soluble pouches comprise water-soluble films coated by a composition. The composition comprises silica flow aid and an absorbent material selected from the group consisting of zeolite; over-dried zeolite; talc; starch; zinc stearate; calcium stearate; micronized calcium carbonate; sodium carbonate; micronized sodium sulphate; and combinations thereof.
US09290724B2 Laundry detergent particles
The present invention provides a coated lenticular or disc detergent particle having perpendicular dimensions x, y and z, wherein x is from 1 to 2 mm, y is from 2 to 8 mm and z is from 2 to 8 mm, wherein the particle comprises: (i) from 40 to 90 wt % surfactant selected from anionic surfactant and non-ionic surfactant; (ii) from 1 to 40 wt % water soluble inorganic salts; and (iii) from 0.0001 to 0.1 wt % dye, wherein the dye is covalently bound to from 1 to 4 sulphonate groups, wherein the inorganic salts and the dye are present on the detergent particle as a coating and the surfactant is present as a core.
US09290720B2 Thickener containing a cationic polymer and softening composition containing said thickener, in particular for textiles
A method for softening laundry employs a softening composition, which includes at least one thickener containing a cationic polymer obtained by polymerization: of a cationic monomer; of a monomer with a hydrophobic nature, of formula (I): wherein R1=H or CH3 R2=alkyl chain having at least 16 carbon atoms X=O, m≧5, y=z=0, or X=NH, m≧z≧5, y=0, or X=NH, m≧y≧5, z=0, of a nonionic monomer.
US09290717B1 Reactor for degumming
A reactor is used for degumming vegetable oil to increase yield and reduce phosphatides. The reactor includes an annular obstruction with multiple circumferential spacers that form ring gaps around a center body having a tapered surface. The circumferential spacers and ring gaps form decompression stages for explosively mixing the oil with degumming agents. Impurities are transferred to the degumming agents and further separation of the components can be carried out to produce a refined oil product.
US09290715B2 Grease composition
A calcium complex grease composition is disclosed. The grease composition has a high dropping point and a suitable thickness and is stable to heat.
US09290714B2 Galling-resistant threaded tubular component and process for coating said component
A galling-resistant threaded tubular component for drilling or operating hydrocarbon wells includes at one of its ends a threaded zone produced on its external or internal peripheral surface depending on whether the threaded end is male or female in type, with at least one portion of the threaded zone being coated with a dry film with a crystalline structure with a high specific surface area principally constituted by one or more mineral salts which are not reactive towards metals, and a process for coating such a component using a dry mineral film with a crystalline structure having a high specific surface area principally constituted by one or more mineral salts which are not reactive towards metals.
US09290713B2 Base oil blend upgrading process with a group II base oil to yield improved mini-rotary viscometer results
A process for improving MRV performance and decreasing wax crystallization in a lubricating oil, comprising: replacing between about 5 to 60 wt % of a base oil or base oil blend with between about 5 to 60 wt % of a Group II base oil. A resultant multigrade engine oil affords a Mini-Rotary Viscosity (MRV) at −30° C. of less than 60,000 mPa·s with no yield stress. The multigrade engine oil, comprising: (a) between about 10 to 30 wt % of a Group II base oil and (b) between about 40 to 60 wt % of a Group I paraffinic base oil characterized by: (i) a VI from about 98 to 104, and (ii) a kinematic viscosity from about 4.5 to 5.5 cSt at 100° C., and (c) an additive package.
US09290709B2 Gasification reactor and process for entrained-flow gasification
A process and device for the gasification of liquid or fine-grain solid fuel materials with the aid of oxygenous, gaseous gasification agents in a reactor is described. Liquid slag is separated on the walls of the reactor. The synthesis gas is generated in a first reaction chamber arranged in the upper part of the reactor and the feedstock is fed to the upper part. Liquid slag precipitates on its lateral walls, with free downflow and no solidification of the slag surface. The lower side has a hole with a slag drop-off edge, from which the generated synthesis gas can be withdrawn in downward direction and the liquid slag can drop off the edge. A second chamber which is delimited by a water film is located under the opening and used to keep the synthesis gas dry and cool. A third chamber is adjacent to the bottom of the second and fed with water to cool the synthesis gas. A water bath is adjacent the bottom of the third chamber and collects the slag particles already solidified and dropped off or those particles still in the liquid phase. The synthesis gas is withdrawn from the pressure vessel in an area below or on the side of the third chamber but in any case located above the water bath.
US09290700B2 Method for preparing synthetic liquid hydrocarbons from CO and H2
The invention relates to synthesis of liquid C5 and higher hydrocarbons from CO and H2 according to the Fischer-Tropsch synthesis. An object is to provide high syngas conversion rate, minimum content of waxes in the products, high content of C10-C20 fractions per pass within a single reactor and avoidance of use of expensive catalyst components. The claimed method for preparing synthetic liquid hydrocarbons by catalytic conversion of a syngas according to the Fischer-Tropsch synthesis comprises sequential passing the reaction mixture through at least four layers of a multilayer fixed bed of granulated catalysts, wherein a first layer in the direction of passing the reaction mixture comprises a cobalt Fischer-Tropsch synthesis catalyst that provides occurring the Fischer-Tropsch synthesis at Anderson-Schulz-Flory factor of 0.67 to 0.96, a second layer in the direction of passing the reaction mixture comprises a traditional cobalt Fischer-Tropsch synthesis catalyst that provides occurring the Fischer-Tropsch synthesis at Anderson-Schulz-Flory factor of 0.82 to 0.96, a third layer in the direction of passing the reaction mixture comprises not less than 30% of H-form zeolite, and a lowermost layer comprises a traditional cobalt Fischer-Tropsch synthesis catalyst that provides occurring the Fischer-Tropsch synthesis at Anderson-Schulz-Flory factor of 0.82 to 0.96. The cobalt Fischer-Tropsch synthesis catalyst of the first layer has thermal conductivity not less than 4 watt/m·K and comprises not more than 10% of skeleton cobalt to decrease heat generation intensity in the front layer and not less than 20% of H-form zeolite.
US09290698B2 Biobased polyols for potential use as flame retardants in polyurethane and polyester applications
The invention provides for new flame retardant non-furan dicarboxylic acid (FDCA) based polyols; oligomers and polymers made from these new polyols with flame retardation properties; and methods of using them as a part or all of the flame retardation composition/material, such as foams and binders.
US09290696B2 Soil improvement agent composition
The invention provides a soil improvement agent composition which contains (A) a fatty acid polyoxyalkylene alkyl ether represented by formula (1): R1CO (EO)m (PO)n OR2 (1) wherein R1 is a straight-chain or branched hydrocarbon group having 13 to 21 carbon atoms, EO represents ethylene oxide, m is a number of 2 to 10, PO represents propylene oxide, n is a number of 1 to 4, and R2 is a hydrocarbon group having 1 to 3 carbon atoms; and (B) a polyoxyalkylene alkyl ether represented by formula (2): R3O (EO)x (PO)y H (2) wherein R3 is a straight-chain or branched hydrocarbon group having 8 to 14 carbon atoms, EO represents ethylene oxide, x is a number of 7 to 12, PO represents propylene oxide, and y is a number of 0 to 3.
US09290695B2 Method for manufacturing a thin-film semiconductor device using an etching solution for an aluminum oxide film
An etching solution includes: phosphoric acid having concentration of 30% by weight to 80% by weight; nitric acid having concentration of 10% by weight or less; and surfactant having concentration of 0.0005% by weight to 0.0050% by weight, wherein the etching solution is used for etching an aluminum oxide film having film density of 2.80 g/cm3 to 3.25 g/cm3.
US09290693B2 Composition containing a core-shell aluminate, phosphor obtained from said composition, and preparation methods
A composition comprising an inorganic core and an aluminate shell is described. The aluminate can have the formula (1): (CeaTbb)Mg1+xAl11+yO19+x+y  (1), where a, b, x and y comply with the relations a+b=1−0.2≦x≦+0.2 and −0.2≦y≦+0.2, wherein the shell uniformly covers the inorganic core over a thickness of no less than 300 nm. A phosphor is also described that can be obtained by calcinating the composition at a temperature of at least 1200° C.
US09290692B2 Polymer light-emitting material, method for producing the same, and organic electroluminescent device
Disclosed is a polymer light-emitting material for an organic electroluminescent device that displays excellent light-emitting performance and is applicable to a wet process. The polymer light-emitting material for an organic electroluminescent device is obtained by subjecting a thermoplastic resin having an Mw of 2,000-1,000,000 and containing a functional group in a unit constituting the backbone and a metal-containing phosphorescent dopant compound containing a reactive group capable of reacting with the said functional group to a polymer reaction so as to link a phosphorescent dopant moiety derived from the metal-containing phosphorescent dopant compound to the unit constituting the backbone of the thermoplastic resin. The content of the metal derived from the metal containing phosphorescent dopant compound in the said polymer light-emitting material is 0.001-20 wt %.
US09290687B1 Wood-based loss circulation material and method for manufacturing same
A wood-based loss circulation material is formed with a density matched to the density of the drilling fluid to which the loss circulation material will be added. The material is formed from sawdust or fiber pressed under high pressure into high-density pellets. The resulting pellets are brittle, and may be crumbled and screened into particles of an appropriate size for a particular drilling fluid application. Different particle sizes may be employed to prevent seepage or fill voids during the well drilling process. The particles do not disassociate into their constituent materials when in the drilling fluid, and thus maintain their density during use.
US09290686B2 Regenerative compositions for the entrapment of particles and methods for its use
Compositions and methods of removing particulate matter from a surface. An example comprises contacting a kneadable dust removal composition with the surface so that the particulate matter adheres or becomes embedded within the composition, and is removed from the surface with the dust removal composition. Preferably the dust removal composition comprises a polymerized siloxane, more preferably a substituted polymerized siloxane, even more preferably, a non-cross-linked, linear polymerized siloxane. In other embodiments the invention comprises a kneadable dust removal composition, preferably comprising a polymerized siloxane. The dust removal composition may be packaged to be attachable to a broom, sweeper, or mop so that it make used to pick up residue from sweeping, brushing or mopping. In other embodiments the dust removal composition may be packaged in a “twist-up” or other similar package permitting the composition to be extruded or advanced to expose a fresh surface.
US09290685B2 Composition for a refrigerator gasket
A composition for a refrigerator gasket is provided. The composition includes, as a polymer base, a blend of an olefin/α-olefin (OAO) copolymer having a melting point of at least 100° C. and a styrene block copolymer (SBC). The polymer base has a melt index (190° C., 5 kg) of 0.01 to 15 g/10 min.
US09290674B2 Method for preparing a base film of modified polyvinyl alcohol polymer
The present invention provides a base film of modified polyvinyl alcohol as well as a method for preparing the base film of modified polyvinyl alcohol and a polarizer made from the base film. The method includes steps of: (1) executing surface graft modification of nano-silicon dioxide particles with fluorinated silane to obtain a modified nano-silicon dioxide powder; (2) adding the modified nano-silicon dioxide powder obtained from the step (1) to an aqueous solution of polyvinyl alcohol polymer, in order to prepare a composite solution of polyvinyl alcohol polymer; and (3) pouring the composite solution of polyvinyl alcohol polymer prepared from the step (2) onto a surface of a casting substrate to obtain a base film of modified polyvinyl alcohol (PVA). The present invention enhances the heat and humidity resistances and the stability of the PVA base film, and improves its mechanical performance and sticking-resistance.
US09290673B2 Image forming method and image recorded material
Provided is an image forming method capable of obtaining an image which has superior adhesion with a recording substrate having ink non-absorbency or low ink-absorbency and has superior scratch resistance.The ink forming method includes an ink application step of applying a water-based ink containing polymer particles, an amine compound having at least one hydroxyl group, a colorant, and water, onto a recording substrate having ink non-absorbency or low ink-absorbency.
US09290672B2 Ink composition and ink jet recording method
An ink composition includes a coloring material; an alkyl polyol having a boiling point at one atmosphere in the range of 180 to 230° C.; first polymer particles having an average particle diameter of 200 nm or more and an MFT of less than 100° C.; and second polymer particles having an average particle diameter of less than 200 nm and an MFT of 100° C. or more. The ink composition does not substantially contain an alkyl polyol having a boiling point at one atmosphere of 280° C. or more.
US09290668B2 Coated polymeric particulates, and a process for coating polymeric particulates
The instant invention provides coated polymeric particulates, and a method for producing polymeric particulates. The coated polymeric particulates according to the present invention comprise (a) one or more polymeric particulates; and (b) a coating composition present on at least a portion of at least one surface of said polymeric particulate, wherein said coating composition comprises a dispersion comprising: (1) one or more base polymers, (2) one or more stabilizing agents; (3) one or more biocide agents; (4) one or more neutralizing agents; and (5) water.
US09290666B2 Laminate and method for manufacturing the same
A laminate includes a substrate, and a surface layer laminated on the substrate with an intermediate layer sandwiched therebetween. The intermediate layer has a thickness of 8 to 40 μm. The surface layer has a thickness 0.4 to 1.5 times that of the intermediate layer. The laminate satisfies the following (A) and/or (B): (A) tan δ (loss tangent) of the intermediate layer as measured under a condition of a vibration frequency of 1 Hz at 20° C. is 0.2 or greater; and (B) A ratio (MG/SG) of a storage modulus (MG) of the intermediate layer to a storage modulus (SG) of the surface layer as measured under a condition of a vibration frequency of 1 Hz at 20° C. is 0.003 or greater and 0.14 or less.
US09290665B2 Coated fullerenes, compositions and dielectrics made therefrom
The present invention relates to coated fullerenes comprising a layer of at least one inorganic material covering at least a portion of at least one surface of a fullerene and methods for making. The present invention further relates to composites comprising the coated fullerenes of the present invention and further comprising polymers, ceramics, and/or inorganic oxides. A coated fullerene interconnect device where at least two fullerenes are contacting each other to form a spontaneous interconnect is also disclosed as well as methods of making. In addition, dielectric films comprising the coated fullerenes of the present invention and methods of making are further disclosed.
US09290658B2 Blends of biorenewable polyamides and methods of making the same
The invention discloses a method to produce a blended polymer by mixing polyamide 11 and polyamide 6, 10. The method may be utilize melt mixing or may utilize blended solutions. The invention also includes a blended polymer, wherein the blended polymer is produced from polyamide 11 and polyamide 6,10.
US09290655B2 Polycarbonate resin composition having good chemical resistance
A polycarbonate resin composition includes (A) a polycarbonate resin, (B) syndiotactic polystyrene, and (C) modified polyolefin compound including a polar functional group on a polyolefin backbone. The polycarbonate resin compositions can have excellent chemical resistance, impact resistance, weathering resistance, fatigue resistance, thermal stability, mechanical properties, transparency, and/or molding processability.
US09290654B2 Polymer compositions with improved adhesion
Polymer compositions with improved lacquer adhesion comprising A) 30 to 80 parts by wt. of at least one polymer chosen from the group of aromatic polycarbonates and aromatic polyester carbonates, B) 2 to 40 parts by wt. of at least one rubber-free and/or rubber-modified vinyl (co)polymer, the rubber-modified vinyl (co)polymers being prepared in the bulk, solution or suspension polymerization process, C) 0.5 to 20.0 parts by wt. of at least one rubber-modified vinyl (co)polymer prepared in the emulsion polymerization process, D) 2 to 16 parts by wt. of at least one polymer, E) 0 to 35 parts by wt. of at least one inorganic filler or reinforcing substance, F) 0.01 to 20.0 parts by wt. of at least one polymer additive, wherein the sum of the parts by weight of components A+B+C+D+E+F in the composition is 100.
US09290651B2 Electrically neutral dispersions and method of preparing same
The invention is a method of producing an essentially electrically neutral polymer dispersion, comprising a polymerizing one or more monomers in the presence of a nonionic surfactant, wherein the polymerization preferably occurs in the absence of ionic surfactants. The invention also includes methods of producing positively or negatively charged polymer dispersions comprising producing the essentially nonionic polymer dispersion and further adding a cationically-charged or anionically-charged surfactant or electrolyte. The invention further includes dispersions produced by the methods of the invention and polymer films and powders produced from these dispersions.
US09290645B2 Cycle time reduction masterbatches and their use in thermoplastic compounds
A masterbatch for a thermoplastic compound is disclosed, comprising fly ash and/or cinders and a carrier thermoplastic resin, compatible with or the same as the thermoplastic resin used in the compound. The amount of fly ash and/or cinders comprises at least 50 percent by weight of the masterbatch. Presence of the fly ash and/or cinders can reduce cycle time for molding of the compound into a plastic article by from about 5 percent to about 30 percent merely because of the presence of the fly ash and/or cinders.
US09290642B2 Process for improving the flow rate of an aqueous dispersion
A process for improving the flow rate of an aqueous dispersion which comprises adding a natural polymer to said aqueous system and then adding a synthetic polymer to the aqueous system.
US09290640B2 Bio-based binders for insulation and non-woven mats
An aqueous binder composition is provided that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a dedusting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided.
US09290638B2 Resin additive, polyphenylene sulfide resin composition, and electronic device
A resin additive for a polyphenylene sulfide includes a diamine compound expressed by a following general chemical formula (1), in which A is an oxygen atom or a sulfur atom, X is a hydrogen atom, an alkyl group with a carbon number of six or less, or an aryl group, and n is a natural number of 1 to 10. A polyphenylene sulfide resin composition includes the resin additive and a polyphenylene sulfide resin. An electronic device includes a molded product of the polyphenylene sulfide resin composition.
US09290636B2 Resin composition, molded article, multilayered pipe and method for producing the same
An object of the present invention is to provide a multilayered pipe having a layer comprising a resin composition containing EVOH, which is unlikely to exhibit the occurrence of cracking in the EVOH layer due to oxidative degeneration and has excellent gas barrier property even during long-term usage at high temperatures, and also to provide a resin composition for obtaining the multilayered pipe. The present invention relates to a resin composition containing 0.001 to 5 parts by mass of an antioxidant (B) and 0.00001 to 0.3 parts by mass of a conjugated polyene compound (C) having a molecular weight of 1000 or less, relative to 100 parts by mass of an ethylene-vinyl alcohol copolymer (A).
US09290634B2 Unvulcanized rubber composition, process for producing same, and pneumatic tire
A process for producing an unvulcanized rubber composition comprising a rubber wet master batch yielded by using, as raw materials, at least a filler, a dispersing solvent and a rubber latex solution, the rubber latex solution comprising two or more rubber latex solution species different from each other, and the process comprising a step (I) of dispersing the filler into the dispersing solvent to produce a filler-containing slurry solution, a step (II) of mixing the filler-containing slurry solution with the rubber latex solution to produce a filler-containing rubber latex solution, and a step (III) of coagulating and drying the filler-containing rubber latex solution to produce the rubber wet master batch.
US09290633B2 Interconnected microcellular material made of industrial lignin and method for preparing same
An interconnected microcellular material, a method for preparing said material using low-value waste from the paper industry, such as industrial lignin, and the use thereof for the production of items such as catalysts, filters or absorbent elements.
US09290632B2 Elastomer product with covalently bonded particles
The invention relates to a method of bonding particles to the surface of an elastomer, in particular a glove, the surface of the elastomer being at least partially epoxidized, and the particles are covalently bonded to the epoxide groups after epoxidation of the elastomer surface.
US09290629B2 Process for producing high molecular weight polyethylene
The invention relates to a process for producing an (ultra) high molecular weight polyethylene (HMWPE) article comprising: incorporating into the HMWPE resin a Hindered Amine Light Stabilizer (HALS) and cross-link the (U)HMWPE during or after molding the (U)HMWPE resin. In particular the invention relates to a process comprising the following steps: a) incorporating into (U)HMWPE resin a Hindered Amine Light Stabilizer (HALS) according to one of the following general formulas or combinations hereof:  wherein R1 up to and including R5 are herein independent substituents; for example containing hydrogen, ether, ester, amine, amide, alkyl, alkenyl, alkynyl, aralkyl, cycloalkyl and/or aryl groups, which substituents may in turn contain functional groups, for example alcohols, ketones, anhydrides, imines, siloxanes, ethers, carboxyl groups, aldehydes, esters, amides, imides, amines, nitriles, ethers, urethanes and any combination thereof; b) molding the (U)HMWPE resin comprising the HALS, resulting in an article; c) cross-linking and sterilizing the article via gamma radiation or electron beam radiation; d) optionally, if step b results in a stock shape, machining the stock shape into an article; wherein step c and step d can be performed in either order.
US09290626B2 Method for preparing a masterbatch of diene elastomer and silica
Preparation of a masterbatch of diene elastomer and silica including preparing at least one silica dispersion in water; bringing into contact and mixing an elastomer latex and the aqueous silica dispersion in the presence of a calcium salt in order to obtain a coagulum; and recovering the coagulum and drying the recovered coagulum in order to obtain the masterbatch. The molar content of calcium cations, defined as the number of moles of calcium cations of the calcium salt per BET unit area of the silica, is between 1.19*10−6 and 2.81*10−6 mol/m2.
US09290624B2 Process for manufacturing fluoroelastomer compositions containing fluoroplastic fibrils
Disclosed herein is a process for the manufacture of a fluoroelastomer composition containing fluoropolymer fibrils. The process comprises applying shear to a fluoroelastomer gum in a mixer while adding a liquid dispersion of fibrillatable fluoropolymer.
US09290622B2 Process and device for polymerizing lactams molds
The invention relates to a process and device for polymerizing lactams in molds wherein the monomer, catalyst and initiator are independently fed to a mixing head feeding a mold. The system in turn comprises a series of feeding and recirculation conduits and reservoirs the temperature of which is regulated to perform the polymerization in a controlled manner.
US09290620B2 Production and composition of glycerol based polyols
The invention provides a method of efficiently producing branched, cyclic glycerol-based polyols with a co-product as anti-biodegrading agent from inexpensive readily available glycerol monomer. The method involves polymerizing glycerol or glycerol with at least another monomer to multiple other monomers in the presence of particular amount of a strong base as the catalyst under a particular distillation environment. The polyol produced by the inventive method is beneficial of reducing scales in Bayer liquid for aluminum production process and improving brightness of coated paper substrates without greening effect.
US09290617B2 Method of biomolecule immobilization on polymers using click-type chemistry
The present invention provides a method for the covalent immobilization of biomolecules on polymers for delivery of the biomolecules, which has the advantage of being simple, highly efficient, environmentally friendly and free of side products relative to traditional immobilization techniques. The invention provides a modified micro/nanoparticle system, which uses a functionalized polymer formed into micro or nanoparticles to bind a molecule to the particles using uses facile chemistry, the Diels-Alder cycloaddition between a diene and a dienophile with the polymer being functionalized with one of them and the molecule with the other, or the Huisgen 1,3-dipolar cycloaddition between a terminal alkyne and an azide to bind the molecule to the particle. The molecules and/or other therapeutic agents may be encapsulated within the polymer particles for intravenous therapeutic delivery. The invention also provides a novel synthetic biodegradable polymer, a furan/alkyne-functionalized poly(trimethylene carbonate) (PTMC)-based polymer, whose composition can be designed to meet the defined physical and chemical property requirements. In one example, the particle system self-aggregates from functionalized PTMC-based copolymers containing poly(ethylene glycol) (PEG) segments. The composition of the copolymers can be designed to meet various particle system requirements, including size, thermodynamic stability, surface PEG density, drug encapsulation capacity and biomolecule immobilization capacity.
US09290615B2 Toner polyester resin, method for producing same, and toner
This toner polyester resin contains 5-30 mass % of a constitutional unit derived from isosorbide, and has a storage elastic modulus (G′) at 180° C. of 400-1,000 Pa. This method for producing the toner polyester resin involves polycondensing a mixture containing 5-30 mass % of isosorbide and a polycarboxylic acid at 230° C. or lower, and completing a polycondensation reaction at a softening temperature in the range of 135-150° C.
US09290612B2 Compositions and devices of poly-4-hydroxybutyrate
Compositions of P4HB with high purity have been developed. The compositions are prepared by washing P4HB biomass prior to solvent extraction, and precipitating P4HB from solution. The same solvent is preferably used to wash the P4HB biomass, and as a non-solvent to precipitate the polymer from a P4HB solvent solution. The highly pure P4HB compositions are suitable for preparing implants. The implants may be used for the repair of soft and hard tissues.
US09290611B2 Production and use of polymers comprising hydroxyl groups and acrylate groups
The present invention relates to polymers which contain hydroxyl groups and acrylate groups, to processes for preparing them, and to their use.
US09290609B2 Hardener for epoxy resins
The present invention concerns low-odor, low-viscosity hardeners for epoxy resins, including an amine with at least one amino group of formula (I) and an amine with at least one amino group of formula (II), wherein the amino groups of formulas (I) and (II) are present in a particular ratio. These hardeners harden quickly with epoxy resins and without blushing to form films of high hardness and good resistance. They are especially suitable for low-emission coatings.
US09290606B2 MDI based linings and membranes from prepolymers with very low free monomeric isocyanates
The present invention relates to a two part polyurethane and/or polyurethane polyurea hybrid based system for making an elastomeric material, comprising an Iso part having low free monomer and an amine/polyol part, wherein the Iso part comprises a pre-polymer of polyurethane, and wherein the pre-polymer is an MDI based pre-polymer with low free MDI monomer and capped with isocyanate groups from a second relatively higher vapor pressure isocyanate and the pre-polymer contains less than about 0.3% total free monomer and has an NCO % in the range of about 0.1 to about 10%.
US09290604B2 NPE-free emulsifiers for water-blown polyurethane spray foam
Alkylethoxylate alcohols or mixtures of alkyl alcohol ethoxylate with an average HLB value between 10 and 15 as compatibilizers for water blown polyurethane foam formulations that are substantially free of nonylphenol ethoxylates are disclosed. The HLB is defined as the mass percent of average structure of the compatibilizer that is hydrophilic, divided by 5. The compatibilizer is mixed into the B-side of the polyurethane formulation. The B-side of the spray foam formulations comprise polyol, water, amine catalyst, and the compatibilizer of the invention such that the water is present at about 2% to about 30% by weight of the B-side formulation, and the compatibilizer is present at about 1% to about 30% by weight of the B-side formulation. The B-side of the formulation may further comprise metal catalysts, flame retardants, silicone surfactants, cell openers, antioxidants, as well as other additives.
US09290603B2 Amines having secondary aliphatic amino groups
The present invention relates to novel amides having secondary amino groups, a process for preparing them, adducts of these amines and their uses. The amides can be prepared in a simple way from readily available starting materials. They and their adducts have, in particular, a low viscosity and are suitable as constituent of polyurethane and polyurea compositions having excellent processability and high flexibility, and also as constituent of epoxy resin compositions, in particular coatings.
US09290601B2 Process for the preparation of tunable fluorescent polymer composition
Disclosed herein is a tunable fluorescent polymer composition comprising silk and one or more polymerizable monomer provided with fluorescent probe, wherein, the said one or more polymerizable monomer provided with fluorescent probe is grafted onto the silk backbone at the a-position of the amide useful in optoelectronics.
US09290600B2 Foam produced from polypropylene with low gel content
Process for providing a polypropylene composition comprising a branched polypropylene in which a polypropylene with a melt flow rate MFR2 (230° C.) of more than 0.5 g/10 min is reacted with a thermally decomposing free radical-forming agent and optionally with a bifunctionally unsaturated monomer obtaining thereby the branched polypropylene, wherein the polypropylene composition has a F30 melt strength of more than 20.0 cN and a V30 melt extensibility of more than 200 mm/s.
US09290598B2 Dioxaborinane co-polymers and uses thereof
A co-polymer includes a polymerization product of: a first monomer: and a second monomer represented by (R1O)(R2O)B-L-X1—PG2 where: L is absent, or is alkylenyl, alkenylenyl, or arylene, wherein the alkylenyl and alkenylenyl are optionally interrupted with one or more oxygen or sulfur atoms; X1 is absent, or is amino, oxo, thio, or phosphino; PG2 is a polymerizable group; R1 and R2 are independently H, alkyl, alkenyl, aryl, C(O)R3, C(O)OR3, C(O)NHR3, or R1 and R2 together with the oxygen atoms to which they are bonded join to form a 5- or 6-membered ring; and R3 is H, alkyl, alkenyl, or aryl, wherein the alkyl and alkenyl are optionally interrupted with one or more oxygen or sulfur atoms.
US09290597B2 (Meth)acrylate compound, optical composition, molded article, and optical element
An optical element including a molded article is provided, the molded article being prepared by molding a polymer prepared by polymerizing a (meth)acrylate compound represented at least by the following general formula (1): wherein a and b are each an integer of 1 or 2; X and Y are each —S— or —O—; R1 and R2 are each an alkyl group having 1 or 2 carbon atoms or a hydrogen atom; and Z1 and Z2 are each an alkyl group having 1 or 2 carbon atoms, having a substituent and represented by the following general formula (2): wherein m is selected from 0 and 1; W is a hydrogen atom or a methyl group; and V is selected from substituents represented by the following: *—O—CnH2n—O—**; *—S—CnH2n—S—**; and *—S—CnH2n—O—**, wherein * represents a bond with an alkyl group; ** represents a bond with a (meth)acryloyl group; n is selected from 2, 3 and 4; and at least one hydrogen atom of —CnH2n— is replaced by a methyl group.
US09290595B2 Process for the production of a flouroolefin/vinyl alcohol copolymer
To provide a process for producing a fluoroolefin/vinyl alcohol copolymer with sufficiently high productivity and excellent heat resistance, whereby a quality loss by coloration is prevented, and a fluoroolefin/vinyl alcohol copolymer obtainable by such a process. A process for producing a fluoroolefin/vinyl alcohol copolymer, which comprises a polymerization step of copolymerizing a specific fluoroolefin and a vinyl ether having a hydrogen atom of a hydroxy group of a vinyl alcohol substituted with a protective group which can be deprotected, and a deprotection step of substituting the protective group in polymerized units based on the vinyl ether in the copolymer obtained in the polymerization step, with a hydrogen atom to form a hydroxyl group, and the fluoroolefin/vinyl alcohol copolymer obtainable by such a process.
US09290591B2 Iron complexes and methods for polymerization
Provided are methods of preparing polymers, such as polyisoprene, polybutadiene, polypiperylene, polycyclohexadiene, poly-β-farnesene, or poly-β-myrcene, using iron complexes. Also provided are novel iron complexes, pre-catalysts, intermediates, and ligands useful in the inventive polymerization system.
US09290586B2 Solid catalyst component, catalyst comprising said solid component, and process for the (CO)polymerization of α-olefins
A solid catalyst component for the (co)polymerization of α-olefins having general formula (I): ZrnMAlxClMgp (I) wherein: M represents titanium (Ti), vanadium (V), or mixtures thereof; n is a number ranging from 0.01 to 2; x is a number ranging from 0.1 to 4; y is a number ranging from 5 to 53; p is a number ranging from 0 to 15; obtained by means of a process comprising putting at least one zirconium arene in contact with at least one metal compound and, optionally, with at least one compound of magnesium. Said solid catalyst component can be advantageously used as a solid component in a catalyst for the (co)polymerization of α-olefins. Said catalyst can be advantageously used in a process for the (co)polymerization of α-olefins.
US09290584B2 Polyalkylene carboxylic acid polyamine additives for fouling mitigation in hydrocarbon refining processes
Methods and systems for reducing fouling, including particulate-induced fouling, in a hydrocarbon refining process including the steps of providing a crude hydrocarbon for a refining process and adding an antifouling agent containing a polymer base unit and a polyamine group to the crude hydrocarbon are provided. The antifouling agent can be obtained by converting a vinyl terminated polymer, such as polypropylene or poly(ethylene-co-propylene), to a terminal acyl containing functional group, followed by reacting the terminal acyl containing functional group with a polyamine compound.
US09290575B2 Compositions comprising RANK/RANKL antagonists and related compounds for treating pain
Disclosed herein are method of treating pain using comprising RANK/RANKL antagonists.
US09290574B2 Methods for treating eosinophilic esophagitis by administering an IL-4R inhibitor
The present invention provides methods for treating, preventing or reducing the severity of eosinophilic esophagitis. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4Rα) inhibitor such as an anti-IL-4Rα antibody.
US09290572B2 Integrin α-Vβ8 neutralizing antibody
The present invention relates to αvβ8 antagonists, anti-αvβ8 antibodies or immunoconjugates for reducing TGFβ activation in an individual. Further provided are compositions comprising one of the αvβ8 antagonists, anti-αvβ8 antibodies or immunoconjugates, methods for using the compositions, and related subject matter.
US09290561B2 Factor VIII, von Willebrand factor or complexes thereof with prolonged in vivo half-life
The present invention relates to modified nucleic acid sequences coding for coagulation factor VIII (FVIII) and for von Willebrand factor (VWF) as well as complexes thereof and their derivatives, recombinant expression vectors containing such nucleic acid sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives coded for by said nucleic acid sequences which recombinant polypeptides and derivatives do have biological activities together with prolonged in vivo half-life and/or improved in vivo recovery compared to the unmodified wild-type protein. The invention also relates to corresponding FVIII sequences that result in improved expression yield. The present invention further relates to processes for the manufacture of such recombinant proteins and their derivatives. The invention also relates to a transfer vector for use in human gene therapy, which comprises such modified nucleic acid sequences.
US09290558B2 Molecular signature of cancer
The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
US09290555B2 Reagents and methods for treating dental disease
Reagents and methods for treating dental disease are provided.
US09290551B2 Compounds for treating papilloma virus infection
The present invention relates to polyamide compositions and therapies for treating cells and subjects infected with papilloma virus.
US09290549B2 Chromatography ligand comprising domain C from Staphylococcus aureus protein A for antibody isolation
The present invention relates to a chromatography ligand, which comprises Domain C from Staphylococcus protein A (SpA), or a functional fragment or variant thereof. The chromatography ligand presents an advantageous capability of withstanding harsh cleaning in place (CIP) conditions, and is capable of binding Fab fragments of antibodies. The ligand may be provided with a terminal coupling group, such as arginine or cysteine, to facilitate its coupling to an insoluble carrier such as beads or a membrane. The invention also relates to a process of using the ligand in isolation of antibodies, and to a purification protocol which may include washing steps and/or regeneration with alkali.
US09290542B2 Pharmaceutical composition for preventing or treating arteriosclerosis
The present invention provides a pharmaceutical composition for preventing or treating arteriosclerosis, comprising: a pharmaceutically effective amount of a protein comprising the amino acid sequence of SEQ ID NO: 1; and a pharmaceutically acceptable carrier. The composition of the present invention exhibits no toxicity in the liver or kidney and effectively reduces the formation of atherosclerotic plaques, thereby exhibiting efficacy in treating arteriosclerosis.
US09290538B2 Cell-permeable peptide inhibitors of the JNK signal transduction pathway
Protein kinase inhibitors and more specifically inhibitors of the protein kinase c-Jun amino terminal kinase are herein described. Additionally, JNK inhibitor sequences, chimeric peptides, nucleic acids encoding same as well as pharmaceutical compositions for treating pathophysiologies associated with JNK signaling are herein provided.
US09290537B2 Method for cross-linking peptides
The present invention relates to a method for cross-linking peptides using an activated furan-moiety. In particular, the present invention provides a method for cross-linking peptides comprising the steps of: a) providing a composition comprising furan-peptides, said furan-peptides comprising at least one amino acid comprising a furan-moiety; b) contacting said composition comprising furan-peptides with second peptides, thereby obtaining a mixture comprising furan-peptides and second peptides; c) adding an activation signal to said mixture of step b), thereby activating said furan-peptides to activated furan-peptides, and d) reacting said activated furan-peptides with said second peptides, thereby cross-linking said activated furan-peptides with said second peptides.
US09290525B2 Method for producing cyclic silane compound or salt thereof, salt having cyclic silane dianion, and cyclic silane dianion salt-containing composition
An object of the present invention is to provide a production method that can efficiently produce a cyclic silane compound or a salt thereof with a high yield and to provide a novel salt having a cyclic silane dianion that is easy to handle and a cyclic silane dianion salt-containing composition. The method for producing a cyclic silane compound or a salt thereof of the present invention includes the step of allowing a halosilane compound to react in the presence of at least one of a phosphonium salt and an ammonium salt, and a compound represented by a specific formula.
US09290521B2 Method for protecting hydroxyl or amine or thiol functions, novel compounds with protected hydroxyl or amine or thiol groups, as well novel compounds for the implementation of this method
A novel method of simultaneously protecting two functions which are same or different, namely hydroxyl, amine, or thiol ones, particularly in sugars, polyalcohols, nucleosides, nucleotides, peptides, and nucleic acids during an organic synthesis, and to novel compounds for implementing this method, as well as to the method of obtaining these compounds. Method of simultaneously protecting two hydroxyl, amine, or thiol functions according to the invention by carrying out a protecting reaction between a compound having at least two free hydroxyl, amine, or thiol groups, and the disilane of formula 1, where R stands for Cl or Br, or I, or a substituent of formula 2, where X1, X2, X3, X4 are the same or different.
US09290520B2 Cyclic diol-derived blocked mercaptofunctional silane compositions
Diol derived blocked mercaptofunctional silane compositions in which the silanes comprise cyclic and bridged alkoxy groups derived from hydrocarbon-based diols and processes for their preparation are provided. Also provided are rubber compositions comprising the cyclic diol-derived blocked mercaptofunctional silanes, processes for their preparation and articles of manufacture comprising the rubber compositions, in particular, automotive tires and components thereof.
US09290519B2 Pyridyldiamido transition metal complexes, production and use thereof
Pyridyldiamido transition metal complexes are disclosed for use in alkene polymerization.
US09290518B2 Water soluble metal-organic frameworks (MOFs)
An efficient, one step solution state processing of Proton Conducting Homochiral Metal Organic Framework has been achieved by using derivate of amino acid and Zn(II) salt as a MOF constructor. Control over MOF solubility as well as proton conductivity has also been achieved by judicious selection of the ligand architecture. This invention will lead the way for ease preparation of MOF films for industrial application.
US09290516B2 Benzobis(thiadiazole) derivative and organic electronics device comprising same
A benzobis(thiadiazole) derivative represented by the formula (1): in which R represents a group containing at least one fluorine atom (with the proviso that fluorine atom (F) and trifluoromethyl group (—CF3) are excluded), and m represents an integer of from 1 to 10.
US09290515B2 Cephem derivative having catechol group
A compound represented by formula (I) or a pharmaceutically acceptable salt thereof wherein A represents a group represented by one of formulae (i)-(iii); B represents a group represented by formula (v) or (vi); and E represents a substituted or unsubstituted heterocyclic group having a cationic nitrogen atom.
US09290512B2 Activators of human pyruvate kinase
Disclosed are pyruvate kinase M2 activators, which are, bis sulfonamide piperazinyl compounds of Formula (I) and 2,4-disubstituted 4H-thieno[3,2-b]pyrrole-2-(substituted benzyl)pyridazin-3(2H)ones of Formula (II), wherein L and R1 to R16 are as defined herein, that are useful in treating a number of diseases that are treatable by the activation of PKM2, for example, cancer and anemia, Formulas (I); (II).
US09290510B2 Polymeric compound and electronic element
A polymer compound including a structural unit represented by formula (I) or a structural unit represented by formula (III) and a structural unit represented by formula (II) has high photoelectric conversion efficiency when used in an organic photoelectric conversion device. wherein Ar1 and Ar2 are the same or different and represent trivalent heterocyclic group; Z represents a divalent group; Y represents a divalent heterocyclic group; wherein Ar1 and Ar2 are the same or different and represent trivalent heterocyclic group; Z represents a divalent group; Y represents a divalent heterocyclic group; two Ar1s may be the same or different; two Ar2s may be the same or different; and two Z's may be the same or different. -D-  (II) wherein D represents an arylene group or a heteroarylene group having a fused ring, provided that a divalent heterocyclic group represented by Y is different from a group represented by D.
US09290507B2 B-RAF kinase inhibitors
The present invention encompasses compounds of general formula (1) where in the groups R0 to R3 and L are defined as in claim 1, which are suitable for the 5 treatment of diseases characterized by excessive or abnormal cell proliferation, pharmaceutical preparations which contain compounds of this kind and their use as medicaments.
US09290504B2 4-imidazopyridazin-1-yl-benzamides and 4-imidazotriazin-1-yl-benzamides as Btk inhibitors
The present invention relates to 6-5 membered fused pyridine ring compounds according to formula (I) or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Brutons Tyrosine Kinase (Btk) mediated disorders.
US09290502B2 Pteridines useful as HCV inhibitors and methods for the preparation thereof
The present invention relates to the use of pteridines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to compounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceutical compositions comprising them, and combinations of said compounds with other anti-HCV agents.
US09290495B2 Tetracationic cyclophanes and their use in the sequestration of polyaromatic hydrocarbons by way of complexation
Novel tetracationic cyclophanes incorporating π-electron poor organic compounds into their ring structures, as well as methods of making the cyclophanes, are provided. The cyclophanes are able to form electron donor-acceptor complexes with a variety of polyaromatic hydrocarbons (PAHs) ranging in size, shape, and electron density. Also provided are methods of using the cyclophanes in the sequestration of PAHs in liquid or gaseous samples, the separation of PAHs from liquid or gaseous samples, the detection of PAHs in liquid samples, and the exfoliation of graphene via pseudopolyrotaxane formation.
US09290494B2 Systems for the light-induced separation of charges
Organic systems having a light-absorbing unit and a unit causing separation of charges are described. Said organic systems efficiently separate charges induced by light and have high lightfastness.
US09290492B2 Solid forms of antibiotics
The invention relates to novel solid forms of fluoroquinolones, in particular to complex co-crystals and to solvates, hydrates and polymorphs thereof. These substances can be used to prepare a pharmaceutical composition containing same as an active ingredient, which can be used as an antibiotic. The compounds have a storage stability that is constant and above that of the salts or hydrates thereof.
US09290489B2 Activation of TRPV4 ion channel by physical stimuli and critical role for TRPV4 in organ-specific inflammation and itch
Provided are TRPV4 inhibitor compounds. Further provided are compositions including a TRPV4 inhibitor compound in combination with a carrier, vehicle, or diluent that is suitable for topical application. The TRPV4 inhibitor compounds and compositions may be used in methods of treating and/or preventing dermatological disorders, reducing skin inflammation, reducing pain, and/or reducing itch in a subject in need thereof.
US09290487B2 Pharmaceutical composition for treating diabetes
Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. In the formula, Ar is an aromatic carbocyclic ring or a heterocyclic ring; and Ar2 is represented by any one of the following rings and the like.
US09290486B1 Compositions and methods for the treatment of epilepsy
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing neurological diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of epilepsy, bipolar disorder, trigeminal neuralgia, attention-deficit hyperactivity disorder, partial seizures, adjunctive therapy for partial, myoclonic, tonic-clonic seizures and schizophrenia, neuropathic pain, seizures, Tourette syndrome, Alzheimer's disease, autism, bipolar disorder and anxiety disorder, bipolar disorder, mania, phantom limb syndrome, complex regional pain syndrome, paroxysmal extreme pain disorder, neuromyotonia, intermittent explosive disorder, borderline personality disorder, myotonia congenita and post-traumatic stress disorder.
US09290485B2 N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
US09290480B2 Quinazoline-2,4-dione derivative, and medical compositions for the prophylaxis and treatment of cranial nerve disease containing the same
The present invention relates to a novel quinazoline-2,4-dione derivative of formula (I), a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising a compound of formula (I) as an active ingredient for preventing or treating neurological brain disease.
US09290479B2 Solid salt forms of a pyrrole substituted 2-indolinone
The present invention relates to solid salt forms of the 3-pyrrole substituted 2-indolinone compound 5-[5-fluoro-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-pirrolidin-1-yl-ethyl)-amide. It also relates to polymorphs of the phosphate salt of the amide. The invention further relates to the use of the salts and polymorphs in the treatment of protein kinase related disorders.
US09290478B2 Substituted quinoxalines as FGFR kinase inhibitors
The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
US09290475B2 3-(substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same
The invention provides 3-deuterium-enriched 3-(6-, 7-, or 8-substituted-4-oxoquinazolin-3(4H)-yl)-piperidine-2,6-diones, deuterated derivatives thereof, stereoisomers thereof, pharmaceutically acceptable salt forms thereof, and methods of treatment using the same.
US09290473B2 Inhibitors of phosphatidylinositol-3-kinase (PI3) and inducers of nitric oxide (NO)
The present invention relates to compounds of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.
US09290467B2 Cyclic amides
The invention relates to a compound of formula (I) wherein A, B, D and R1 to R6 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
US09290465B2 Substituted isoxazole amine compounds as inhibitors of SCD1
The invention is concerned with a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
US09290460B2 1-(Arylmethyl)quinazoline-2,4(1H,3H)-diones as PARP inhibitors and the use thereof
Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity.
US09290459B1 Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
US09290457B2 Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
Substituted dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and which are useful as medicaments for the treatment of, inter alia, COPD. Exemplary is
US09290453B2 Quinolines and aza-quinolines as CRTH2 receptor modulators
The invention provides certain quinolines and aza-quinolines of the Formula (I), and their pharmaceutically acceptable salts, wherein E, J1, Ja, Jb, R2, R3, R22, Ra, Rb, Rc, Rd, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
US09290445B2 Methods of synthesizing a levodopa ester prodrug
Methods of synthesizing a levodopa ester prodrug, salts thereof, and synthetic intermediates thereof are disclosed.
US09290443B2 Preparation of 4-amino-2,4-dioxobutanoic acid
A process for synthesizing 4-amino-2,4-dioxobutanoate involves reacting a dialkyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding an alkyl cyano acetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl 2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl 2-cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoate. The 4-amino-2,4-dioxobutanoate may be acidified into 4-amino-2,4-dioxobutanoic acid.
US09290442B2 Preparation of 4-amino-2,4-dioxobutanoic acid
A process for synthesizing 4-amino-2,4-dioxobutanoic acid involves reacting diethyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding ethyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl 2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl 2-cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoic acid.
US09290438B2 Method for starting a reaction during the production of aromatic amines from nitroaromatics
The present invention relates to a method of producing aromatic amines by hydrogenation of aromatic nitro compounds. This method provides a reactor containing a hydrogenation catalyst; supplies aromatic nitro compounds and hydrogen to the reactor and contacts them with a hydrogenation catalyst, in which the hydrogen which is supplied to the reactor is by a compressor and the compressor contains an operating fluid which at least partially contacts the hydrogen; and regenerates the hydrogenation catalyst by heating and contacting it with oxygen. Particular operating liquids are subsequently exchanged.
US09290426B2 Method of making oxygenates from a non-catalytic chemical reaction
A system and a method for forming oxygenates from a non-catalytic reaction. A hydrocarbon gas and an oxygen-containing gas are fed into a mixer and then heated to form a reactant gas stream. The reactant gas stream is fed into a fluidized bed reactor where the reaction of the gases occurs by oxidization to produce oxygenates. The oxygenate products are then removed from the reactor.
US09290423B2 Process of generating a renewable biofuel from a hydrotreated stream of condensed oxygenates
A renewable fuel may be obtained from a bio-oil containing C3-C5 oxygenates. In a first step, the bio-oil is subjected to a condensation reaction in which the oxygenates undergo a carbon-carbon bond forming reaction to produce a stream containing C6+ oxygenates. In a second step, the stream is hydrotreated to produce C6+ hydrocarbons.
US09290421B2 Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof
The present invention relates to a compound having formula (I): wherein: —X is in particular 125I Or 211At; —R1 and R′1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; —R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; —Z is a heteroatom, R5, R8 and R9 are preferably H; —Y is preferably an electron withdrawing group.
US09290419B2 Duplex actuation system for inflatable restraints
A duplex firing initiator for an airbag inflator includes both a primary initiator and a secondary initiator for electrical connection to a Restraint Control Module. In the duplex firing initiator, current is conducted in a forward polarity through the primary initiator to actuate the primary initiator and current is conducted in a reverse polarity through the secondary initiator to actuate at least the secondary initiator.
US09290415B1 Fire resistant cementitious composite and method of making the same
The fire resistant cementitious composite is an engineered cementitious composite (EEC) having both flexural strength and fire resistant properties. The fire resistant cementitious composite includes a binder mixture formed from Portland cement and fly ash, sand, polyvinyl alcohol fibers, a polycarboxylic ether polymer and water. In the binder mixture, a weight ratio of the fly ash to the Portland cement is between approximately 1.0 and approximately 1.3. A weight ratio of the Portland cement to the sand is between approximately 0.85 and approximately 1.0. A weight ratio of the water to the binder mixture is between approximately 0.28 and approximately 0.33. The sand is preferably Arabian Gulf dune sand.
US09290414B2 Glass strand provided with a polymer-based coating and screen comprising said strand
The present invention relates to a glass strand having a coating including a polymer chosen from vinyl acetate/vinyl chloride copolymers, polyvinyl chloride and polyvinylidene chloride, and a silane of formula (I).
US09290413B2 Ion exchangeable glass with high compressive stress
An aluminosilicate glass article having a high compressive stress layer. The glass article comprises at least about 50 mol % SiO2 and at least about 11 mol % Na2O, and has a layer under a compressive stress of at least about 900 MPa and the depth of layer that extends at least about 30 μm from the surface of the glass article into the glass. A method of making such a glass article is also provided.
US09290404B2 Free-formed quartz glass ingots and method for making same
A method to form quartz glass ingots of ultra low contamination and defect levels by firing a high-purity quartz form as the feedstock, wherein the quartz glass ingot is free-formed on a platen rotating concentrically with the feedstock quartz article.
US09290394B2 Method for decomposing organic compound contained in aqueous solution
Provided is a method for decomposing at least one of organic compound contained in an aqueous solution by using a titanium dioxide photocatalyst that is excellent in both photocatalytic activity and solid-liquid separation performance for water treatment. The method includes: a step of adding catalyst particles into the aqueous solution; a step of decomposing the organic compound by irradiating the aqueous solution with light having a wavelength of 200 nanometers or more and 400 nanometers or less while stirring the catalyst particles in the aqueous solution; and a step of stopping the stirring, and separating the catalyst particles from the aqueous solution by sedimentation. The catalyst particles are composed only of titanium dioxide particles and zeolite particles, the titanium dioxide particles are adsorbed on outer surfaces of the zeolite particles, the zeolite particles have a silica/alumina molar ratio of 10 or more, and the catalyst particles are contained in the aqueous solution at a concentration of 0.4 grams/liter or more and 16 grams/liter or less.
US09290390B2 Activated charcoal
The invention provides a method for preparing activated charcoal from a precursor material comprising high mineral content plant or algal material by heating the precursor material under suitable conditions sufficient to produce activated charcoal therefrom. The invention also provides various applications of the activated charcoal per se.
US09290389B2 Graphene composite and a method of manufacturing a graphene composite
A method including providing graphene on a growth substrate; providing a target substrate on the graphene to form a first composite including the target substrate and graphene; and removing at least a portion of the first composite from the growth substrate.
US09290387B2 Preparation of arrays of long carbon nanotubes using catalyst structure
A structure for preparing an substantially aligned array of carbon nanotubes include a substrate having a first side and a second side, a buffer layer on the first side of the substrate, a catalyst on the buffer layer, and a plurality of channels through the structure for allowing a gaseous carbon source to enter the substrate at the second side and flow through the structure to the catalyst. After preparing the array, a fiber of carbon nanotubes may be spun from the array. Prior to spinning, the array can be immersed in a polymer solution. After spinning, the polymer can be cured.
US09290382B2 Rapid detection of replicating cells
The invention enables efficient, rapid, and sensitive enumeration of living cells by detecting microscopic colonies derived from in situ cell division using large area imaging. Microbial enumeration tests based on the invention address an important problem in clinical and industrial microbiology—the long time needed for detection in traditional tests—while retaining key advantages of the traditional methods based on microbial culture. Embodiments of the invention include non-destructive aseptic methods for detecting cellular microcolonies without labeling reagents. These methods allow for the generation of pure cultures which can be used for microbial identification and determination of antimicrobial resistance.
US09290381B2 Functionalized single-walled nanotubes and methods thereof
Described are single-walled metal oxide nanotubes having a plurality of organic functional units or moieties bonded generally in a covalent manner to the inner wall of the single-walled nanotubes. Functionalization of the single-walled metal oxide nanotubes is performed in a single-step during synthesis of the nanotubes. The organic functional units are found dispersed throughout the length of the inner wall and not sterically hindered or contained at only the mouth or ends of the single-walled metal oxide nanotubes.
US09290380B2 Reducing MEMS stiction by deposition of nanoclusters
A mechanism for reducing stiction in a MEMS device by decreasing surface area between two surfaces that can come into close contact is provided. Reduction in contact surface area is achieved by increasing surface roughness of one or both of the surfaces. The increased roughness is provided by forming a micro-masking layer on a sacrificial layer used in formation of the MEMS device, and then etching the surface of the sacrificial layer. The micro-masking layer can be formed using nanoclusters. When a next portion of the MEMS device is formed on the sacrificial layer, this portion will take on the roughness characteristics imparted on the sacrificial layer by the etch process. The rougher surface decreases the surface area available for contact in the MEMS device and, in turn, decreases the area through which stiction can be imparted.
US09290379B2 Chip package including a microphone structure and a method of manufacturing the same
In various embodiments, a method for manufacturing a chip package is provided. The method includes arranging a chip over a substrate, the chip including a microphone structure and an opening to the microphone structure; and encapsulating the chip with encapsulation material such that the opening is kept at least partially free from the encapsulation material.
US09290378B2 MEMS capping method
A method for fabricating a MEMS device includes providing a substrate having a front surface and a back surface, and forming a protruding engagement member on the front surface of the substrate. The protruding engagement member has an inner periphery defining a groove and an outer periphery. The method also includes forming a first trench having a first depth along the outer periphery, forming a patterned mask layer on the protruding engagement member covering the groove and exposing a portion of the first trench. The method further includes etching the exposed portion of the first trench to form a second trench having a second depth, removing the patterned mask layer, bonding the substrate with a MEMS substrate to form the MEMS device, and thinning the back surface to within the second depth. The method prevents dust from being deposited on the MEMS substrate as in the case of cutting.
US09290377B2 Method of stacking a plurality of dies to form a stacked semiconductor device, and stacked semiconductor device
A method of stacking a plurality of first dies to a respective plurality of second dies, each one of the first dies having a surface including a surface coupling region which is substantially flat, each one of the second dies having a respective surface including a respective surface coupling region which is substantially flat, the method comprising the steps of: forming, by means of a screen printing technique, an adhesive layer on the first dies at the respective surface coupling regions; and arranging the surface coupling region of each second die in direct physical contact with a respective adhesive layer of a respective first die among said plurality of first dies.
US09290375B2 Complementary metal oxide semiconductor (CMOS) ultrasonic transducers and methods for forming the same
Complementary metal oxide semiconductor (CMOS) ultrasonic transducers (CUTs) and methods for forming CUTs are described. The CUTs may include monolithically integrated ultrasonic transducers and integrated circuits for operating in connection with the transducers. The CUTs may be used in ultrasound devices such as ultrasound imaging devices and/or high intensity focused ultrasound (HIFU) devices.
US09290374B2 Micro-electro-mechanical system device having differential capacitors of corresponding sizes
The invention provides a micro-electro-mechanical device having differential capacitor of corresponding sizes, which includes a substrate; a top fixed electrode; a bottom fixed electrode; a mass, having a top electrode and a bottom electrode, wherein the top electrodes form a top capacitor with the top fixed electrode and the bottom electrodes form a bottom capacitor with the bottom fixed electrode; a top fixed electrode extension wall having an upper end connected to the top fixed electrode and a lower end connected to the substrate; and a bottom fixed electrode extension wall having a lower end connected to the substrate through the bottom electrode, wherein the bottom fixed electrode extension wall has no upper end connected to the top fixed electrode, and total areas of the top fixed electrode extension wall and the top fixed electrode facing the mass are substantially equal to total areas of the bottom fixed electrode extension wall and the bottom fixed electrode facing the mass.
US09290372B2 Fluid distributor unit
A fluid distributor for uniformly distributing flow of a feed onto a chromatography column in a cost-effective way defines a distribution channel of generally conical shape between a solid back plate and a packed bed in the column, wherein the fluid distributor comprises at least two circular and/or annular fluid-permeable porous disks essentially filling the volume of the distribution channel.
US09290367B2 Tissue roll-handling clamp
A tissue roll handling clamp, mountable on a vehicle such as a lift truck, has elongate, substantially equal-length, thin clamp arms with opposed tissue-engagement clamping surfaces. The clamp arms are capable of movement in unison by a frame assembly to alternative positions where the clamp arms extend longitudinally from the frame assembly selectively in either substantially horizontal or substantially vertical directions of extension. The frame assembly is capable of maintaining the respective clamping surfaces at substantially equal elevations to each other during such movement to substantially equalize the distribution of the weight of a clamped tissue roll between the opposed tissue-engagement clamping surfaces.
US09290363B2 Tailor welded panel beam for construction machine and method of manufacturing
A beam for use in construction equipment is made from tailor welded panels. At least one of the panels is made from at least two pieces of material such as steel welded together with the weld running the length of the beam. The weld between pieces of steel can either be parallel to the longitudinal axis of the beam, or the pieces can be tapered and the weld will be at an angle diverging from the longitudinal axis of the beam. The two pieces of material have a different compressive strength per unit of length in a direction transverse to the longitudinal axis of the beam. In some embodiments a top panel is welded to two side panels to form two top corners of the beam and a bottom panel is welded to the two side panels to form two bottom corners of the beam.
US09290361B2 Lifting device efficient load delivery, load monitoring, collision avoidance, and load hazard avoidance
A lifting device sensor unit comprises a housing, a first global navigation satellite system (GNSS) receiver, and a wireless transceiver. The housing is configured to removably couple about a load line of a lifting device. The first GNSS receiver is coupled with the housing and configured for determining a sensor unit position in three dimensions. The wireless transceiver is coupled with the housing and configured for wirelessly providing information including the sensor unit position to a display unit located apart from the sensor unit.
US09290359B2 Timer-based control of fixture channels
A method for controlling a fixture (122) includes receiving a message from a controller (102), determining whether the message includes an address associated with the fixture (122), retrieving an identifier of the controller (102) from the message responsive to determining that the message includes an address not associated with the fixture (122), determining whether the fixture (122) includes a fixture channel (204) controlled by the controller (102), and resetting a timer (203) associated with the fixture channel (204) controlled by the controller (102) responsive to determining that the fixture (122) includes the fixture channel (204) controlled by the controller (102).
US09290356B2 Wire transporting system
In a wire-processing machine, a belt-drive feeds a wire to a first swivel-arm with a first gripper. To feed the leading wire-end to processing stations, the first swivel-arm is set in a swiveling motion and/or in a linear motion. To feed the trailing wire-end to processing stations, the second swivel-arm is set in a swiveling motion and/or in a linear motion. After processing of the leading wire-end, by means of the belt-drive the desired cut-off length of wire is advanced and, by means of a transporting system, is transported further.
US09290353B2 Paper money accumulation device
In a paper money accumulation unit (paper money accumulation device) of a paper money handling device, rollers sequentially input paper money from an upper side into a paper money accumulation space. Then, a support member is arranged in a state where the height with respect to an extended line of an input direction becomes large as being away from the rollers to the input direction of the paper money.
US09290351B2 Contact nip roll
An improved contact nip roll, a method for assembling an improved contact nip roll, a system for nipping a web, and a method for nipping a web are provided. The improved contact nip roll integrates an inner softer core that can provide compliancy to web caliper variations, while rigid annular rings and a harder outer skin can maintain a uniform contact area.
US09290346B2 Paper sheet processing apparatus
According to an embodiment, a paper sheet processing apparatus is provided with a conveying device which conveys a paper sheet along a conveying way, a discrimination section 14 which distinguishes a paper sheet, a plurality of accumulation sections which accumulate the paper sheet distinguished, a sorting mechanism which sorts the paper sheet distinguished to one of the accumulation sections, a first sensor which includes an opaque substance sensor which detects an opaque substance and a transparent substance sensor which detects a transparent substance, and which detects a paper sheet which is conveyed, a second sensor which detects a paper sheet which is conveyed, and a controller.
US09290341B2 Sheet conveyor and image forming apparatus incorporating same
A sheet conveyor incorporated in an image forming apparatus includes an attraction/separation unit including an attraction belt, a first tension roller, and a second tension roller, a support member to support the attraction/separation unit, a roller drive unit to rotate one of the first and second tension rollers, a charging member to uniformly charge a surface of the attraction belt, a mechanism to swing the attraction/separation unit to move the attraction belt reciprocally about the support member between a sheet attraction position and a sheet conveyance position being located farther from the sheet stack than the sheet attraction position, and a pressing member disposed inside a loop of the attraction belt to press the attraction belt at the sheet attraction position toward the sheet stack and separating from the attraction belt at the sheet conveyance position.
US09290339B2 Sheet feed cassette, paper sheet conveying device, and image forming apparatus
A sheet feed cassette includes an end cursor, a pair of gears, and a pair of racks. The end cursor regulates a rear end position of stored paper sheets in the sheet feed direction. The end cursor is slidable in the conveyance direction. The pair of gears are rotatably provided on a lower surface of a base portion of the end cursor and have the same module and the same number of teeth. The pair of racks are provided on a bottom surface of a cassette main body in parallel with each other along a slide direction of the end cursor. The pair of racks respectively mesh with the pair of gears. This makes it possible to prevent a defect such as skewing, a folded edge, or a wrinkle from occurring, allowing the end cursor to slide smoothly with excellent operability.
US09290336B2 Variable width central alignment system with blocking of reverse and forward movement of trucks for loading bays
The system comprises at last one longitudinal guide that is independent of the loading bay and disposed on one side of the vertical mid-plane of the loading bay, facing the plane defined by the loading bay and associated with actuating means that trigger the lateral movement thereof, forming a reference for guiding the truck as it is maneuvered towards the loading bay. At least one of the longitudinal guides comprises a vertical post including illuminated signalling means and detectors for detecting the height and width of the truck approaching the loading bay, as well as moveable wedges associated with actuating means for blocking the truck in the loading bay.
US09290334B2 Working system provided with servo-controlled automatic operating door
A working system including: a working machine having a door operated so as to be closed at a time of working and be opened at a time of non-working; an automatic changer provided so as to enter and exit from an inside of the working machine through the door to change a worked object and/or a tool; and an actuator operating the door. The actuator is a servo motor dedicated to operating the door.
US09290323B2 Recirculating continuous storage apparatus
A continuous storage apparatus holds carriers each having many vertical shelves to be continuously loaded and unloaded by pushers at adjacent positions. The conveyor order of arrival of items is maintained on departure. Shelves hold items to be frozen or cooked during storage by a forward or backward (countercurrent) flow of recirculating cold or hot air within the tunnels of the machine. Carrier motion is provided by lifting and lowering conveyor chains at both ends of the tunnels and by shunting the carriers, supported by wheels or skids on rails along the tunnels, when pushed by an actuator.
US09290322B2 Article store
An article store is provided with vertical main supports, front and rear crossmembers arranged transversally to the storage and retrieval directions and fastened on the main supports, and at least one bearing profile extending in the storage and retrieval directions and supported vertically relative to the front crossmember. The upper side of the bearing profile is located in a plane higher than the upper edge of the front crossmember and forms a bearing device for the articles. The bearing profile is supported vertically on the front crossmember by a support whose upper end is connected to the bearing profile. The front crossmember is provided with form-fit structures in order to fix the vertical support of the bearing profile at least in the longitudinal crossmember direction. The lower end of the support engages form-fit structures of the front crossmember.
US09290318B2 Hopper and medicine supply apparatus including the same
A hopper having a passage through which a medicine can be passed downward is provided. The hopper is configured to cause rippling vibration on an inner surface thereof by an external force applied to the hopper. According to this configuration, the rippling vibration applies a force to the medicine to separate the medicine away from the inner surface of the hopper. This prevents the medicine from easily adhering to the hopper.
US09290314B2 Packet for tobacco products
Described is a packet for tobacco products comprising two containers of tobacco products each substantially having the shape of a parallelepiped and provided with two larger side walls, two smaller side walls, a bottom wall and a top wall, the packet has an outer wrapper having at least one connection panel and at least two additional panels, in particular the containers are connected to the outer wrapper at the at least one connection panel; the packet is provided with a lid, hinged along a first hinge to one of the additional panels, which is able to rotate between a closed position and an open position of the packet and, in the closed position, keeping each of the two additional panels in contact with a respective larger side wall of each container.
US09290313B2 Insulated shipping bags
A collapsible insulated bag designed to allow items retained within an inner pouch thereof to remain within predetermined temperature ranges for predetermined periods of time and wherein the bags are designed to be easily compressed or compacted for storage or shipment to end users. The bags include at least an outer reflective layer, an intermediate open foam layer and the inner pouch layer.
US09290311B2 Sealed containment tube
A containment tube includes a sealed tube comprising silicon carbide, first and second ends, an inner bore extending along at least a portion of its axial length between the first and second ends, and contains a radioactive material within the bore of the sealed tube. The first end has a plug residing in the inner bore to close the first end, and the second end has a distal wall that closes the inner bore at the second. At least one of the first or second ends is bonded to the sealed tube by a sinter bond.
US09290310B2 Resealable lid container
A container for holding contents includes a shell having a peripheral rim defining a substantially open top, a lid positioned on the shell, covering the substantially open top, and having a peripheral portion engaging the peripheral rim, and a liner disposed within the shell, conforming to the shape of the shell, and having peripheral ribbon secured to the lid forming a continuous seal between the liner and the lid.
US09290306B2 Tamper evident closure for flexible containers
A closure for flexible containers or pouches that contain food products that provides at least two visual indicators showing that the cap has been partially or totally unscrewed from the spout. The first indicator is a tab in a window section of the cap that has its mounting filaments or bridges broken when the cap is unscrewed. These filaments or bridges connect the tab to the top portion of the cap. The second indicator is a vertical break or rupture line in the tab that indicates that the tab has been bent to rupturing.
US09290304B2 Device for packing bulk products, especially for food
A packaging device (1) for bulk goods (3), particularly for use for foods such as coffee beans, cocoa beans, rice, spices and seeds in general, includes at least one vacuum bag (2) defining an open side (2d) for insertion of the bulk goods (3) therein and hermetically sealable at the open side (2d) subsequent to evacuation of the air contained therein.
US09290303B2 Thermoplastic films with enhanced resistance to puncture and tear
The present invention relates to a thermoplastic film having improved tear and puncture resistance. The thermoplastic has a plurality of embossed regions that are comprised of a plurality of parallel, linear embosses. The plurality of embossed regions is arranged so that a straight line cannot traverse the thermoplastic film without intersecting at least one of the plurality of embossed regions.
US09290301B2 Packaging of multiple cups
Devices and methods for packaging food cups is provided. The devices include unitary blanks with a front panel, bottom panel, rear panel, top panel, and side closures (in various forms) configured for assembly into a hollow substantially polyhedral package enclosure for 2 cups, 4 cups, or other even number of cups. Package enclosures with different side closures are designed for assembly with no glue joints, one glue joint, 3 glue joints (two cup enclosure), or 5 glue joints. Package enclosures provide visual displays that permit viewing of contents of cups secured in the enclosures. Package enclosures are structurally stable for packaging, transport, and storage. And the visual displays provide aesthetic appeal for consumers. Material and manufacturing costs and product waste are minimized with the invention.
US09290290B2 Reusable box blank
A blank for being repeatably assembled into a box configuration without the use of adhesives. The blank has a bottom panel, a side panel foldably attached to the bottom panel, an end panel foldably attached to the bottom panel, and a locking structure configured to secure the side panel and the end panel in respective orthogonal positions with respect to the bottom panel. The locking structure includes an overlay panel foldably attached to the end panel and foldable toward an overlying position in which it overlies a portion of the side panel. The locking structure also includes a slot in the bottom panel, a flap foldably attached to the bottom panel and extending into the slot, and a tab foldably attached to the overlay panel for being lockingly received in the slot to secure the overlay panel in the overlying position.
US09290287B2 Foamed and stretched plastic containers and method of producing the same
A foamed and stretched plastic container having a basic structure which includes a mouth portion and a body wall continuous to the mouth portion and is stretch-formed, the body wall forming a foamed region where foamed cells are distributed, and the mouth portion being an unfoamed region where no foamed cell is present, wherein the foamed cells present in the foamed region have a flat shape being stretched in the direction of stretch, and the foamed cells positioned in the central portion in the direction of thickness of the container wall have the largest lengths in the direction of maximum stretch.
US09290284B2 Product wrapping machine
A product wrapping machine includes a feed mechanism by which products to be wrapped are directed on entry, in ordered succession, to a take-up station, a wrapping device including a first conveyor, rotatable continuously about a respective axis, a second conveyor rotatable intermittently about a respective axis, and a transfer device by which the products are gripped in succession at the take-up station and fed to the wrapping device. The first conveyor includes a plurality of carriers, mounted rotatably on it and equipped with gripper heads. Each carrier is associated with a respective motion-inducing device designed to move the carrier in such a way as to enable the carrier to interface and interact with a respective gripper element of the second conveyor.
US09290280B2 Method for producing a container intended to contain a substance to be dispensed by an airless pump, and a container produced by the method
A method for producing a container intended to contain a substance to be dispensed by an airless pump, having an external body inside which a bag is provided formed of thermoplastic material, the bag presenting, at least at a connection surface between its neck and its lateral surface, controlled deformation zones arranged to guide the bag deformation in accordance with preferential directions. The invention also relates to a container formed by the described method and a bag with the aforedescribed characteristics.
US09290278B2 Systems and methods for launching space vehicles
Systems and methods for launching space vehicles into orbit involve placing a space vehicle into a protective container. The protective container is placed on a sled in a maglev tunnel and then launched into the atmosphere. Once the protective container reaches a certain height the space vehicle is released from the protective container and the space vehicle then proceeds to the desired orbital position.
US09290277B2 Surveillance system and surveillance method
Provided are a surveillance system and a surveillance method. The surveillance system includes a control tower configured to be coupled with and separated from a flying vehicle, and receive an image captured by the flying vehicle through a first communication network, wherein the control tower is further configured to transmit the received image to a central control station through a second communication network for analysis of the received image. The surveillance system may further include the flying vehicle and the central control station.
US09290276B2 Lightning protection fastener and aircraft
An aircraft of the present invention includes an outer panel 4 made of a fiber reinforced plastic material, a support member 5, and a lightning protection fastener 1. The fastener 1 includes a metal fastener body 2 having a shaft portion 10 and a head portion 20, and an insulating member 30 made of an insulating plastic material and mounted to the head portion 20. The portion 20 has a frustoconical-shaped fastener seat surface 211. The panel 4 includes a receiving surface 41 conforming to the fastener seat surface 211. The member 30 includes an insulating seat surface 321 retracted from a plane of the fastener seat surface 211 such that, when a portion 41A of the receiving surface 41 which is opposed to the fastener seat surface 211 is depressed, an insulating seat surface 321 comes into contact with the receiving surface 41.
US09290274B2 Acoustically attenuating sandwich panel constructions
An aircraft engine assembly comprising a nacelle configured to surround the aircraft engine having an inlet open to ambient air and an annular acoustic panel provided within the nacelle. Sound emitted from the aircraft engine is attenuated by the annular acoustic panel. The annular acoustic panel comprises an open framework, made from a first material, forming a plurality of cells.
US09290268B2 Hovering and gliding multi-wing flapping micro aerial vehicle
Multi-wing hovering and gliding flapping Micro Air Vehicles (“MAV”) are disclosed. The MAV can have independent wing control to provide enhance energy efficiency and high maneuverability. Power to each wing can be controlled separately by varying the amplitude of the wing flapping, the frequency of the wing flapping, or both. The flapping frequency can be controlled such that it is at or near the natural frequency of the wings for improved energy efficiency. The wings can be controlled by a gear train, coil-magnet arrangement or many other actuation systems that enable variable frequency flapping, variable amplitude flapping, or a combination of both. The gear train mechanism provides gyroscopic stability during flight. The wing flapping can include a rotation, or feathering motion, for improved efficiency. The wings can be transitioned between flapping flight and fixed wing flight to enable gliding and hovering in a single configuration.
US09290266B2 Speed control assembly and methods of using same
A speed control assembly includes an input drive shaft coupled to a first gear subassembly having a rotatable gear, a second gear subassembly coupled to an output drive shaft, and a linkage coupling the first and second gear subassemblies, wherein the input drive shaft, the first and second gear subassemblies, and the linkage are configured such that a rotational speed of the rotatable gear adjusts a ratio of a rotational speed of the output drive shaft to a rotational speed of the output drive shaft. In some embodiments, the first gear subassembly includes a sun gear coupled to the input drive shaft, one or more planet gears, and a ring gear as the rotatable gear. In some embodiments, the second gear subassembly includes a sun gear coupled to the output drive shaft, one or more planet gears, and a fixed ring gear.
US09290262B2 Method for creating a vertical trajectory profile comprising multiple altitude levels
A method for creating a vertical trajectory profile of an aircraft by optimization of a criterion representative of a flight cost, comprises: performing a first iterative computation of a profile free of altitude constraints as long as a condition dependent on the criterion is not reached, replacing each free level of the constraint-free profile with a permitted level so as to generate an initial constrained profile comprising a plurality of permitted levels, and, for each level, an altitude change point and a plurality of speeds, and performing a second iterative computation of a profile in which the altitude levels to be reached remain constant, equal to the initial permitted levels of the initial constrained profile, as long as a condition dependent on the criterion is not reached.
US09290261B2 Method and assembly for attaching components
An example adjustable linking member of a mounting assembly includes a first attachment portion and a second attachment portion. The first attachment portion connects a linking member to a first component. The second attachment portion connects the linking member to a second component. A variable portion of the adjustable linking member varies a distance between the first attachment portion and the second attachment portion in a first direction when heated. The variable portion varies the distance between the first attachment portion and the second attachment portion in a second direction when cooled. The first direction is opposite the second direction.
US09290259B2 Aircraft nose with cockpit and avionics bay modules integrated therein
An aircraft nose comprising a primary fuselage structure, and housed inside said structure, a cockpit, and an avionics bay containing a plurality of avionics racks designed to receive electrical and/or electronic equipment. The cockpit and the avionics bay are each made in the form of a distinct module that is suitable for being installed in a single operation inside the primary fuselage structure. The use of modules for integrating in the aircraft nose makes it possible to reduce considerably the time required for fitting out the nose on the final assembly line of the aircraft.
US09290254B2 Method and arrangement for controlling a ship propulsion system
In a method for controlling a ship propulsion system wherein, in a first operating mode, the position of a command signal generator within a guide range including a forward and a reverse section is interpreted by a system controller as a desired power output as well as a desired travel direction, a second operating mode is provided wherein the position of the command signal generator is ignored as power output command so that the position of the command signal generator forms only as directional control device and wherein in either mode of operation, the command signal generator is automatically returned to a neutral position when the command signal generator is released by an operator.
US09290251B1 Trolling motor system for a light-weight watercraft
A trolling motor system for a light-weight watercraft comprises: a mounting plate for attachment to the watercraft, the plate includes a fixed end, a moveable end, and a hinge therebetween, a winch is located adjacent the fixed end adapted to raise and lower the movable end between an up position and a down position, a guidance mechanism is coupled to and below the moveable end, and a trolling motor affixed to and located below the guidance mechanism. The system may also include a quick release mechanism coupling the guidance mechanism and trolling motor to the moveable end. The guidance mechanism may include a wire system for controlling rotational movement of the trolling motor. In use, when the watercraft is moved into or out of the water, portions of the system may be easily removed from the watercraft, so that the entire weight of the system is not a hindrance.
US09290243B2 Modularized containerized amphibious vehicle transport
An apparatus for a water vessel, wherein the water vessel includes at least one container configured to transport at least one vehicle, wherein the at least one container is configured to transport the at least one vehicle while the at least one container is in a body of water. The water vessel includes one or more buoyancy floats configured to maintain the at least one container afloat in the body of water. The water vessel includes a propulsion unit configured to navigate the at least one container and the at least one vehicle through the body of water.
US09290241B2 Vessel comprising a crane
A vessel (4) includes a crane (1) connected to a deck (5) of the vessel. The crane (1) includes a frame (10) which is rotatable about a horizontal hinge axis (H), a rotation mechanism (20) connected to the frame (10) at a position away from the horizontal hinge axis (H), arranged to rotate the frame (10) about the horizontal hinge axis (H) from an upper position to a lower position and vice versa, and a swivel member (30), which is with a first end (31) rotatable connected to the deck (5) and which is with a second end (32) rotatable connected to the rotation mechanism (20). The swivel member (30) is rotatable between an inward position associated with the upper position of the frame (10) to an outward position associated with the lower position of the frame (10).
US09290240B1 Deck hook having improved loading functionality
A deck hook capable of accepting loading forces in multiple directions and of distributing such forces over an increased deck surface area thereby reducing the risk of damage to the deck, particularly when the deck is formed of a non-steel material.
US09290239B2 Control device for positioning an instrumented cable provided with buoyancy means for retrieving the control device and instrumented cable from submerged positioning
Control device (10, 20) for controlling the position of an instrumented cable towed in water, such as a marine seismic streamer, and/or an instrumented towed cable array (streamer array), which control device (10, 20) is provided with buoyancy means (30) for retrieving the control device (10, 20) and instrumented cable to the surface, at least sections of the instrumented cable, which means (30) are arranged for providing the control device (10, 20) with buoyancy.
US09290237B1 Hydrofoil
A hydrofoil includes a body, an even number of wings disposed at the opposite sides of the body and an even number of floats disposed at both sides of a bottom of the body. Each float is a hollow and flat structure. At a rear edge of the float portion is provided a float propeller. With the design of the float structure, the counterforce caused by the water waves impacting on the floats can be reduced, so that the float can move more stably to improve safety and comfortableness.
US09290232B2 Variable rate assembly for a brake system for bicycle
A brake assembly for a hydraulic brake system of a handlebar-steered vehicle, the brake assembly including a housing mountable to a handlebar of the vehicle and having a chamber formed therein. The brake assembly is provided with a variable rate linkage. A piston assembly is received and axially guided within the chamber and is provided with a piston adjustment mechanism that does not affect the function of the variable rate linkage.
US09290229B2 Bicycle chain stay coupling
A bicycle chain stay coupling apparatus includes a first bracket component coupled to a seat tube of a bicycle frame, a connecting component of a chain stay of the bicycle frame, and a coupling component encasing the connecting component and coupled to the first bracket component. The coupling component is relatively more elastic than the first bracket component and the connecting component, and the coupling component is positioned in series between the first bracket component and the connecting component with respect to a common axle of the first bracket component, the connecting component, and the coupling component.
US09290226B2 Oil passage structure for electric vehicle
A straddle electric vehicle (e.g., electric motorcycle) comprising a driving motor and an electric power control unit for controlling electric power supplied from batteries to the driving motor, a case of the electric power control unit is mounted to the battery box from outward, and electrode terminals protruding outward from the case are inserted into insertion holes of the battery box. The electrode terminals protruding into inside of the battery box are connected to electrodes of the batteries via electric conductors such as bus bars. In this structure, electric connecting work between the batteries and the electric power control unit can be easily carried out, high-voltage lines can be minimized in length, and the high-voltage lines are not exposed to outside.
US09290223B2 Bike light mounting system
A bicycle and light assembly has wheels, a frame support by the wheels, a bike light supported by the frame, and a mounting system coupling the bike light to the frame. The mounting system includes a socket secured to one of the frame and the bike light, a post secured to the other of the frame and the bike light, and a releasable securing mechanism that secures the post in the socket. The mounting system can further include a mounting bracket coupling the post to the frame, wherein the mounting bracket facilitates rotational adjustment of the post about the post axis. The releasable securing mechanism can include a detent member positioned in a side opening of the socket and in engagement with a recess in the socket to secure the rotational orientation of the post in the socket.
US09290222B1 Adjustable pneumatic bicycle saddle system with improved pump
In an embodiment of the present invention, an improved pump is provided to inflate and deflate a bladder of a seat. The pump has a base, a stem, a valve, a bulb, an O-ring and a cover. The O-ring holds the bulb to the base in a recess defined by two lips. The bulb has a hole in one end that can be covered by a user's finger during inflation, wherein the user compresses the bulb while covering the hole to create pressure within the chamber. Then, when the user contacts the plunger, the pressure causes air to enter the bladder. To deflate the bladder, the user contacts the plunger without covering up the hole in the bulb. The stem has a flange. The pump can connect to a seat by connecting to a seat tab and securing the tab between the flange and the base.
US09290219B2 Locomotion system and method of controlling a robotic device
A locomotion system for use with a robotic device is provided. The locomotion system includes a first micropillar array including at least a first micropillar, a second micropillar array including at least a second micropillar, a control circuit associated with each micropillar of the first and second micropillar arrays, and a controller operatively coupled to each control circuit. The controller is configured to selectively activate the first and second micropillars in a sequence that causes the robotic device to move in a predetermined direction.
US09290216B2 Suspension assembly for personal tracked vehicle
A suspension assembly for a personal tracked vehicle comprises a first swing arm pivotally connectable to a frame of the vehicle. The first swing arm has a first end and a second end. A second swing arm is pivotally connectable to the first swing arm. The second swing arm has a first end and a second end. At least one spring member is connected to the first and second swing arms. At least one first wheel is rotatably connected to the first end of the first swing arm. At least one second wheel is rotatably connected to the first end of the second swing arm. The at least one first and second wheels are adapted to be in contact with the same track of the vehicle. The first and second wheels are one of an idler wheel and a drive wheel. Suspensions and personal tracked vehicles are also presented.
US09290214B2 Portal trailer for a tugger train
A portal trailer for a tugger train, consisting of a front, rear and middle trailer section, between which respectively a receiving area for a dolly to be carried along is provided, wherein the front is connected with the middle and the middle with the rear trailer section each via a portal-shaped arch and the middle trailer section has a pair of rollers or wheels.
US09290213B2 Multi-level trailer
A trailer is provided with a fixed height and length. The trailer has a frame with a hitch located at a front area and wheels mounted to axles at a rear area. The frame has a middle section that has an unobstructed opening where a middle floor rests below a top surface and is surrounded by the middle section. The middle floor is located below an upper floor to form a two-story trailer. A rear floor is located at an elevation between the middle floor and the upper floor.
US09290211B2 Bonding with adhesive beads or plots
A structural member includes one or more walls that define a cavity. A system for reinforcing the cavity includes a substantially rigid carrier configured to reside in the cavity. The carrier includes a pathway disposed in the carrier that provides an aperture between an exterior surface of the carrier and an interior surface of the carrier. An adhesive is disposed in a gap between at least a portion of the exterior surface of the carrier and the wall of the structural member. The adhesive is disposed proximate to the pathway.
US09290208B2 Vehicle body lower portion structure
It is a subject of the present invention to ensure foot space for an occupant and lower a side portion of a floor portion. A vehicle body lower portion structure (10) comprises: a rocker upper member (16) that configures an upper portion of a rocker (12) and has an upper wall portion (16A) that extends in a vehicle width direction, an inner wall portion (16B) that is positioned at a vehicle width direction inner side and a vehicle lower side with respect to the upper wall portion (16A) and extends in a vehicle up-and-down direction, and a connecting wall portion (16D) that interconnects a vehicle width direction inside end portion of the upper wall portion (16A) and an upper end portion of the inner wall portion (16B); a rocker lower member (18) that configures a lower portion of the rocker (12); and a wire harness (28) that extends in a vehicle front-and-rear direction along the rocker (12), with at least part (28A) of the wire harness (28) being positioned, as seen in a vehicle front view, in a cross section formed by the connecting wall portion (16D), an extension line (16E) extending inward in the vehicle width direction from the upper wall portion (16A), and an extension line (16F) extending toward a vehicle upper side from the inner wall portion (16B).
US09290202B2 System and method of calibrating a trailer backup assist system
A system and a method are provided for calibrating a backup assist system for a trailer attached to a vehicle. The method includes driving the vehicle forward substantially straight above a threshold speed, sensing a yaw rate of the vehicle, and sensing a measured hitch angle of the trailer. A yaw sensor continuously senses the yaw rate of the vehicle and a hitch sensor continuously measures the hitch angle for determining an angle rate based on the measured hitch angle. Further, a controller determines an offset between the measured hitch angle and an actual hitch angle when the yaw rate and angle rate are substantially zero or otherwise the same.
US09290199B2 Electric power steering system
An electric power steering system includes: an annular elastic member that is made of resin, that is arranged between an inner end face of a housing and an outer ring of a bearing that supports a cylindrical member that rotates coaxially with a rack shaft, and that supports the cylindrical member such that the cylindrical member is movable in the axial direction with respect to the housing; and a supporting member that restricts axial movement of the cylindrical member within a predetermined range, and that restricts radially inward movement of the elastic member.
US09290190B2 Systems and methods for determining whether a transportation track is occupied
A method for determining whether a defined section of a transportation track is occupied is described. The method includes inducing an audio frequency (AF) signal at a first position on the transportation track and receiving the AF signal at a second position on the transportation track. The defined section of the transportation track is located between the first position and the second position on the transportation track. The method further includes measuring a strength of the AF signal received as a function of time at the second position, and identifying an inflection point of the recorded AF signal strength. The inflection point indicates at least one of a rail vehicle entering the defined section of the transportation track and the rail vehicle exiting the defined section of the transportation track. The method further includes determining an occupancy of the defined section of the transportation track, based on the inflection point.
US09290189B2 Coupler assembly for coupling railway wagons
The coupler assembly for coupling railway wagons comprises a pulling apparatus (10) positioned between a front stop (6) and a rear stop (7) in space between central girders (1, 2) of a railway carriage. The front stop (6) is fixed rigidly to the central girders (1, 2) of the wagon frame. The solution is characterized by the fact that the rear stop (7) is mounted in a moving manner between the central girders (1, 2) of the wagon frame, and a support bracket (9), fixed permanently to the wagon frame, is positioned behind the rear stop (7), whereby an increased energy absorption unit (12) is positioned between the support bracket (9) and the rear stop (7).
US09290186B2 Messaging via vehicle steering wheel
One of a condition affecting a vehicle and a planned action of the vehicle are identified. An instruction is provided to actuate movement of a steering wheel in the vehicle, wherein the movement is determined according to the one of the condition and the planned action.
US09290183B2 Apparatus and method estimating road slope of vehicle
A method of estimating road slope of a vehicle may include determining an offset value of a gravitational acceleration sensor, determining a driving distance in a longitudinal direction of the gravitational acceleration sensor, comparing a difference between a driving distance and the driving distance in the longitudinal direction of the gravitational acceleration sensor with a predetermined value, estimating a road slope by using either a driving torque or the gravitational acceleration sensor based on a result of the comparison, and controlling a shift of the vehicle according to the estimated road slope.
US09290175B2 Vehicle control system
A vehicle control system is provided to control driving force to improve turning performance in a vehicle having an automatic transmission without causing conflict with a shifting control of the transmission. The vehicle control system comprises: a shifting means that carries out a shifting operation of the transmission based on an execution condition including an execution threshold governed by a vehicle speed and an operating amount of an accelerator performed by a driver; a driving force controlling means that carries out a turning performance improving control for stabilizing a vehicle behavior by controlling a driving force during turning; and a shifting condition correcting means that corrects a value of the operating amount of the accelerator as the execution condition during execution of the turning performance improving control.
US09290173B2 Engine start control device for hybrid vehicle
In the present invention, a determination is made as to whether towing travel is under way, in which vehicle weight is increased, and when towing travel is under way, the compensating torque provided by a motor generator is decreased relative to the compensating torque provided during non-towing travel, and the torque of the motor generator is therefore reduced by a commensurate amount and fuel efficiency is enhanced. During towing travel in which the vehicle weight is large, a large drive force is usually necessary and the frequency of use of the motor generator increases; however, the compensating torque during engine start is reduced, and the load on the motor generator is thereby mitigated by a commensurate amount, and overheating and the like are suppressed. Since the inertia of the vehicle is relatively small during non-towing travel, i.e., normal travel, in which the vehicle weight is relatively small, variations in the drive force due to the engine starting torque are relatively increased, and shocks such as a sense of being pulled back become significant. However, because the compensating torque provided by the motor generator is increased correspondingly with the starting torque, shocks are adequately suppressed.
US09290161B2 Vehicle wheel washer
A spray-type washer for a conveyor-type car wash comprises a support stand with a power cylinder that drives a piston. Pins on the piston ride in slots formed in a rotatable cam that is connected to a spray unit such that piston travel produces a swivel motion of a spray unit mounted on the support stand. The spray units use multiple impeller-type sprayers. The washers are used in pairs, one washer on each side of a conveyor lane.
US09290159B1 Air foil systems and methods
An air foil system that can include a complimentary pair of inner and outer air foil elements forming an openings and exits in one cross section, the opening being from 2 and 6 inches in height in the one cross section and the exit being from between about ¾ and 4 inches in height in the one cross section. The complimentary inner and outer air foil elements may form a compression chamber between the complimentary entrance and exit edges, the compression chamber having a height in one cross section that is from ½ inch to about 3 inches. A mounting assembly may be operatively connected to the inner and outer air foil elements for aligning the opening within 5 inches of the rearmost portion of rear-facing portion and mounting the air foil elements to the rear-facing portion of the vehicle. Methods for reducing the co-efficiency of drag and clearing of a rear-facing portion of a vehicle is provided, the method comprising projecting a horizontal airstream passing over a roof of the portion as the vehicle is propelled over a roadway to provide two moving air curtains over the rear-facing portion, reducing the co-efficiency of drag of the portion, and clearing a portion of the rearward surface of the rear-facing portion.
US09290156B2 Connection base interacting with an adapter for forming therewith mechanical connector for the wiper blade for an automobile
The present disclosure relates to a connection base for carrying a wiping blade and to be attached to an adapter that can be connected to an actuation arm for forming with said adapter a mechanical connector for a wiper blade for an automobile, the adapter having an elongated shape with first and second ends, characterised in that it includes a retaining linear guide for the first end of the adapter and removable attachment means of the second end supported on the one hand by the adapter and on the other hand by the base. The present disclosure also relates to a conform adapter, to a mechanical connector formed by the adapter and the connection base, to a planar wiper blade and to a wiping device.
US09290154B2 Apparatus and method for disabling a vehicle
An apparatus for disabling a motor vehicle comprises an expandable head adapted to be inserted and secured into the exhaust pipe of an automobile, motorcycle, go-kart, scooter, boat, tractor or other vehicle having an internal combustion engine. A shaft of the apparatus may be configured to engage with a tool, e.g., a socket wrench, torque wrench, drill driver, or other tool, which may impart a rotational force on the shaft to radially expand a head of the apparatus and secure it within a tailpipe of a vehicle, such that buildup of pressure within the vehicle exhaust system does not expel the apparatus from the pipe. An axial bore through the shaft may be fitted at a terminal end with a pressure release valve to selectively release pressure, e.g., before removing the device, or to allow operation of the vehicle while the apparatus is secured within the tailpipe.
US09290153B2 Vehicle-based multimode discovery
Methods and systems for a device discovery daemon that bases access of a communication device to an on board vehicle network on device location are provided.
US09290149B2 Airbag apparatus for a front passenger seat
An airbag apparatus for a front passenger seat includes an airbag inflatable into a generally square conical contour whose top is deployable at the front end. The airbag is mounted on a case together with an inflator by the periphery of a gas inlet port which is located proximate the front end of the airbag. The airbag includes in a passenger side wall a recessed area that is sunken forward and extends vertically generally at airbag inflation. A seam that joints peripheral edges of a base material of the circumferential wall together extends forward from the recessed area. The seam is slanted off a front and rear direction such that the front end of the seam is directed toward either left or right when the airbag at full inflation is viewed from an up and down direction.
US09290143B2 Deflector for a skateboard
A deflector for a skateboard generally comprises; a sweep plate to deflect in-path debris from the skateboard's line of travel and a sweep plate suspension, which is coupled to the sweep plate and to the skateboard. The sweep plate suspension provides to substantially maintain a sweep plate's position proximate to a ground in response to maneuverings of the skateboard. The sweep plate suspension may further comprise a spring to provide for a flexing of the sweep plate in response to the maneuverings so as to maintain the sweep plate's proximate position. The sweep plate suspension may couple to a truck or a platform of the skateboard, and may also comprise an adjustment mechanism to set the sweep plate's position. The sweep plate may be releasable from the sweep plate suspension, and at least one of the sweep plate and the sweep plate suspension may comprise lights.
US09290142B1 Bumper mounted deployable upper leg catcher for pedestrian protection
A pedestrian protection apparatus for a motor vehicle is disclosed. The apparatus includes a catcher beam and a catcher beam support assembly including a catcher beam support to which the beam is attached. The support is movable between stowed and deployed positions. The apparatus includes a bumper energy absorber and a bumper beam. The assembly is positioned adjacent the absorber and is either substantially within or adjacent to the bumper beam. The apparatus includes a mechanical, electromechanical or pneumatic actuator to allow the support to move to its deployed position. A pedestrian impact sensor sends a signal to a control unit in the event of an imminent pedestrian impact. The control unit then signals the assembly to allow the catcher beam to move to its deployed position using the actuator. In the event of a false positive deployment, the actuator retracts the catcher beam to its stowed position.
US09290137B2 Power supply circuit for vehicle
Disclosed is a power supply circuit for vehicles, which can continuously supply a constant voltage without a complicated circuit configuration, even during a time when a surge voltage is applied (abnormal voltage time). The power supply circuit is provided with: a constant voltage circuit, which is connected to a battery mounted in a vehicle, and which outputs a predetermined voltage; a surge cut circuit, which is provided with a Zener diode and a transistor for protecting the constant voltage circuit; and a switching circuit, which is disposed between the constant voltage circuit and the surge cut circuit, and which performs on/off switching of output to the constant voltage circuit. The power supply circuit is also provided with a feedback line that connects the connecting line (output line) of the switching circuit and the Zener diode to each other.
US09290132B2 Motor vehicle integrated carrier rack and storage system
An integrated carrier rack and storage system for vehicles is provided. Generally, the system includes a receiving unit, installed in a motor vehicle that receives a carrier bar device. The system further includes an immobilizing system attached carrier bar and various attachment units which facilitate in transportation and storage. The integrated carrier rack and storage system is user friendly and may be applied to any motor vehicle to carry an assortment of items and store them using the same system.
US09290130B2 Load and lift roof rack
A roof rack for loading and unloading cargo to and from the roof of a motor vehicle is described. The roof rack is characterized by enabling the cargo to be loaded at an accessible height and then lifted onto the roof of the motor vehicle while the cargo is maintained in a fixed position. In another embodiment, the cargo is reoriented from a first orientation to a second orientation during the loading and unloading procedure.
US09290128B2 Multi-functional vehicle rearview mirror
A multi-functional vehicle rearview mirror that includes a cover, a glass reflecting mirror face, a large sized liquid crystal display device which includes a large sized display screen and a large sized display driver board, wherein the large sized display screen includes a large sized displaying liquid crystal glass and a large sized display device backlight module, wherein the large sized liquid crystal display device is provided with a retention frame and a high obscuration media, wherein a small window with a small sized backlight module and a control circuit is provided. The rearview mirror automatically shifts between multiple cameras via signals from vehicle lamps. The RF modules with little power consumption are embedded into the circuits of the rearview mirror and the cameras for providing the video shift and information communication of the whole system.
US09290125B2 Haptic alert system for a vehicle
A haptic alert system for use in a vehicle includes a sensor system operable to identify a condition associated with the vehicle; a control system in communication with the sensor system; and a remote haptic device in communication with the sensor system.
US09290123B2 Vehicle light system with illuminating roof rack
A vehicle lighting system is provided herein. The lighting system includes a roof rack including at least one side rail having a photoluminescent portion configured to illuminate in at least one distinct color due to being excited by at least one wavelength of light. A light source is configured to emit the at least one wavelength of light directed toward the photoluminescent portion. A controller is configured to control a light output of the light source.
US09290117B2 Armrest lock for vehicle seat
A lock assembly for selectively and releasably holding a pivoting armrest of a vehicle in place relative to an adjacent seat back is disclosed. The lock assembly includes a first locking element fixedly attached to the seat back and a second locking element movably attached to the armrest. Both locking elements have engagement surfaces whereby the second locking element is releasably engageable with the first locking element. The first locking element includes a cover that, together with a base, defines a pocket. The second locking element includes a spring loaded attachment assembly. The assembly provides operator-movable attachment to the armrest. The second locking element further includes an engagement portion on which the engagement surface is formed and an anchoring portion. An operator-manipulable release tab extends from the engagement portion and through the tab-passing slot of the first locking element when the first and second locking elements are engaged.
US09290116B2 Actuator and hardware system for a vehicle seat
The invention relates to an actuator (71) for a vehicle seat, comprising a handle (41) for jointly actuating two locks (23), a force transfer between the handle and each lock, a first indicator (51) associated with the first force transfer, and a second indicator associated with the second force transfer, wherein the two indicators each indicate the respective locking status of the associated lock, and the two indicators actuate an overall indicator (61) by means of a logical OR function in order to visibly indicate the unlocked state. The force transfer is preferably formed from Bowden cables (43).
US09290110B2 Adjusting device, in particular for a vehicle seat
An adjusting device for a vehicle seat includes a guide element for guiding a lever element. The guide element is in contact with a carrier rail. At least one contact region of the guide element includes a profiled chamfer in at least some sections.
US09290108B2 System and method for adaptive battery temperature control of a vehicle over a known route
A system/method for controlling a battery temperature of a vehicle over a known route. The method may include providing a route having a starting and ending location, iteratively sensing a battery temperature of the battery when the vehicle is travelling along the route, and dividing the route into a plurality of route segments. The method may also include storing a known route having a plurality of segments where each segment has a corresponding battery temperature of the vehicle when the vehicle previously travelled along the segment. The method may also include providing a cooling device associated with a battery of the vehicle, initiating the cooling device during a previous time segment when the battery temperature for a particular time segment of the known route exceeds a high temperature threshold, and reducing an amount of battery power draw from the battery during the previous time segment.
US09290107B2 System and method for energy management in an electric vehicle
A vehicular energy management system (EMS) determines a net total power from a traction drive load, an auxiliary device load, and a regenerative power. If the net total power is a net supply power, the EMS causes regenerative power to be provided to a power source and energy source in a controlled manner to initially charge the power source to a desired state-of-charge (SOC) and then subsequently charge the energy source. If the net total power comprises a net power load, the EMS causes power to be drawn from the power source and the energy source, with a split of the power being drawn from the power source and the energy source being based on a magnitude of the net power load. The EMS adjusts/maintains the SOC set-point of the power source and the DC link voltage based on vehicle speed and relative altitude of travel of the vehicle.
US09290106B2 Power control system of hybrid vehicle
A power control system includes a battery, a converter which converts a direct-current voltage of the battery to a different level of direct-current voltage by the switching of switching elements, a second inverter, a second MG which is an electric motor, an engine, and an ECU which is a controller. When there is a warm-up request for the battery, the ECU causes a carrier frequency in the switching control of the switching elements to be lower than a carrier frequency in the case where there is no warm-up request for the battery. When there is a warm-up request, the ECU causes the carrier frequency at which the engine is in operation to be lower than the carrier frequency at which the engine is out of operation.
US09290100B2 Shared swappable energy module
A number of variations may include a product including: a vehicle having a cargo bed and a plurality of electrical contacts provided in the vehicle bed constructed and arranged to be connected to electrical contacts on a module having a battery. A number of variations may include a method comprising: providing a vehicle having a cargo bed and a plurality of electrical contacts provided in the vehicle bed constructed and arranged to be connected to electrical contacts on a module having a battery, the vehicle including an electric motor for propelling the vehicle; providing at least one module, the module including a module battery and an electrical contact connected to the module battery and constructed and arranged to engage one of the electrical contacts provided in the vehicle bed; charging the module battery and loading the module with the charged module battery on the vehicle bed, and supplying power to the electric motor of the vehicle from the module battery.
US09290097B2 Apparatus for transferring energy using onboard power electronics with high-frequency transformer isolation and method of manufacturing same
An apparatus for transferring energy using onboard power electronics with high-frequency transformer isolation includes a power electronic drive circuit comprises a dc bus and a first energy storage device coupled to the dc bus. A first bi-directional dc-to-ac voltage inverter is coupled to the first energy storage device and to the dc bus, and a first electromechanical device coupled to the first bi-directional dc-to-ac voltage inverter. A charging system coupled to the dc bus via a charge bus comprises a receptacle configured to mate with a connector coupled to a voltage source external to the power electronic drive circuit and an isolation transformer configured to electrically isolate the charge bus from the receptacle. A controller configured to cause the charging system to supply a charging voltage to the dc bus based on a voltage received from the voltage source external to the power electronic drive circuit.
US09290095B2 Ignition interlock identification apparatus and method of use thereof
The invention comprises a personal identification device used in function of a peripheral device and/or for communication with an external network. In one embodiment, a non-removable personal identification device communicates presence of a specific individual to a peripheral device, such as an ignition interlock device, a tracking system, and/or a communication system or person, such as a police network, an enforcement agency, a regulatory network, a supervisor, and/or a parent or guardian. For example, information related to the peripheral device reliant in part on the presence of the personal identification device is communicated with the remote system. Optionally, any information associated with the personal identification device and/or the peripheral device is maintained in a secure format warranting true information, usable in a legal setting.
US09290089B2 Forecast of driveline lash condition for multivariable active driveline damping control
A method to predict a driveline lash condition includes monitoring an axle torque request signal, determining a predicted axle torque request value at a lead time based upon the monitored axle torque request signal, and predicting the driveline lash condition at the lead time based upon the predicted axle torque request value indicating an upcoming zero torque condition.
US09290086B2 Sunroof apparatus
In an opening/closing mechanism of a sunroof apparatus, an engaged portion engaged with a cam groove smoothly slides on upper and lower cam surfaces of a cam groove, and stiffness to support a roof panel is increased at low costs. The engaged portion includes a first sliding portion having a convex curve facing upward and sliding on the upper cam surface of the cam groove, and a second sliding portion coupled to the first sliding portion at a front or a rear of a vehicle, having a convex curve facing downward, and sliding on the lower cam surface of the cam groove.
US09290081B2 Ventilation cap
A ventilation cap includes a tube portion, a vent portion, and an upper portion. The tube portion is configured to releasably engage with a vent pipe. The vent portion extends from the tube portion to define a common pathway formed therein. The vent portion has at least three interconnected adjacent sides. Each of the sides includes one or more upright ribs, and multiple contiguous ribs laterally extending from the upright ribs to define openings in fluid communication with the common pathway. The contiguous ribs at one or more sides have an intermediate segment with an increased cross-sectional area. The contiguous ribs taper laterally from the intermediate segment to ends. The upper portion is disposed above the vent portion and connected to an upper end of the upright ribs.
US09290075B2 Coupled torsion beam axle type suspension system
A coupled torsion beam axle type suspension system may include trailing arms respectively coupled to opposite ends of a torsion beam, and vehicle body-engaging units, each provided in a front end portion of a respective trailing arm and engaging the respective trailing arm with a vehicle body. Each vehicle body-engaging unit may includes a trailing arm bush that is coupled to a front end portion of the respective trailing arm, a link bracket disposed in front of the trailing arm bush and engaged with the trailing arm bush in a width direction of a vehicle, a vehicle body mounting bush disposed outside of the trailing arm bush and in front of the trailing arm bush, installed in the link bracket, and engaged with a lower part of the vehicle body in a height direction of the vehicle; and a damper connected to the link bracket and the vehicle body abutting the vehicle body mounting bush.
US09290071B2 Coupler assembly
The present application describes a gooseneck coupler assembly that may include a gooseneck trailer pivot, an extension arm, and a pivot retention mechanism having a ball socket. The ball socket may engage with a hitch ball located on a towing vehicle. The gooseneck trailer pivot may be mounted on a towed vehicle or trailer and be capable of pivoting about a vertical axis relative to the trailer. During engagement, the ball socket and the extension arm may provide tilt capability but thereby prevent any rotational movement relative to the hitch ball. However, the gooseneck coupler assembly may still be able to tilt fore-and-aft or side-to-side relative to the hitch ball. Therefore, the only pivotal movement relative to a vertical axis would be permitted at the gooseneck trailer pivot.
US09290067B2 Pressure sensor with differential capacitive output
A MEMS pressure sensor device is provided that can provide both a linear output with regard to external pressure, and a differential capacitance output so as to improve the signal amplitude level. These benefits are provided through use of a rotating proof mass that generates capacitive output from electrodes configured at both ends of the rotating proof mass. Sensor output can then be generated using a difference between the capacitances generated from the ends of the rotating proof mass. An additional benefit of such a configuration is that the differential capacitance output changes in a more linear fashion with respect to external pressure changes than does a capacitive output from traditional MEMS pressure sensors.
US09290066B2 TPMS sensor position input method
A TPMS (tire pressure monitoring system) sensor input method is disclosed and performed by: using a setting tool to read in the ID of the TPMS sensor subject to the set position, and then compiling the ID of the TPMS sensor and the position to be set into a set code, and then transmitting the set code to a receiver host for enabling the receiver host to store the data of the ID of the TPMS sensor and the position of the TPMS sensor.
US09290064B2 Pneumatic tire
In a pneumatic tire, a height from a turned-up edge of a carcass layer is not more than 10 mm, a distance from a tire outer surface to the carcass layer is not less than 50% of the total gauge, a height of the bead filler is from 50% to 80% of a tire cross-section height, a cross-sectional area ratio VB/VR of the bead filler to a side reinforcing layer is not less than 0.4 and not more than 0.6, a hardness HsB of the bead filler is not less than 65 and not more than 80, and the hardness HsR of the side reinforcing layer is not less than 75 and not more than 85, a size relationship between the hardness HsB and the hardness HsR is HsB≦HsR, a value TB of tan δ is not more than 0.06, and a value TR of tan δ is not more than 0.05.
US09290060B2 Motorcycle tire for rough terrain
A motorcycle tire 1 on rough terrain. Blocks 11 include crown blocks 16 arranged in a center area Cr of a tread portion 2, middle blocks arranged axially outside the crown blocks and shoulder blocks arranged axially outside middle blocks. The crown blocks have a smallest aspect ratio. The shoulder blocks have a largest aspect ratio. The crown block 16 includes a shift block. The shift block is provided in a center part in its widthwise direction with one circumferentially extending slit so as to divide the block into two small block segments. The two small block segments are shifted from each other in the tire circumferential direction.
US09290057B2 All season safety tire
A vehicle tire includes a selectively actuated stud deployment system for increased traction. The studs are contained in cells in the surface of the tire and forced to deploy by pneumatic or fluid pressure. When the pressure is released, the studs retract.
US09290056B2 Pneumatic tire
The pneumatic tire 1 includes a belt layer 14 that is formed by laminating a plurality of belt plies 141 to 145 including the circumferential reinforcing layer 145. Also, the belt layer 14 includes at least two belt plies on the outer side in the tire radial direction of the circumferential reinforcing layer 145. Also, the intercord distances T1 to Tk have a relationship such that T1≦T2≦ . . . ≦Tk and T1
US09290052B2 Pneumatic tire
A tire includes a tread portion, a pair of opposing sidewall portions, and a pair of shoulder portions each arranged between the tread portion and one of the sidewall portions, wherein at least on one side of the tire the sidewall and shoulder portions comprise at least a first rubber compound and a second rubber compound, the second rubber compound having a material composition different from that of the first rubber compound.
US09290048B2 Wheel built-in locking system and method
A wheel having an axle receiving bore. The bore having at least one finger integral with the wheel extending towards the front wall of the wheel. The finger having a detent facing inwardly into the axle receiving bore. The finger is flexed outwards for insertion of the axle within the axle receiving bore, and flexed inwards to insert the detent into a notch of the axle once the axle is inserted in the axle receiving bore.
US09290046B2 Low efficiency bicycle wheel system and method
A low efficiency wheel system and method, the system includes an inner, propelled wheel and an outer wheel circumferentially adjacent the inner wheel. The system includes an efficiency reduction apparatus located between the inner wheel outer circumferential surface and the outer wheel inner circumferential edge to reduce the efficiency of the inner wheel as it transfers motion to the outer wheel. Such efficiency reduction apparatus may include a reducing drive roller assembly, reducing drive gear assembly, bearing assemblies, raceway restrictions, or combinations thereof.
US09290044B2 Oil hub cap
The present invention is directed to an oil hub cap comprising a cylindrical body for mounting to a wheel axle defining an interior space for holding lubricant oil and a transparent front face. An indicating ring is located within the interior space, such that the outside edge of the indicating ring indicates the minimum amount of lubricant to be contained within the interior space and the inside edge of the indicating ring indicates the maximum amount of lubricant to be contained within the interior space, the surface of the indicating ring between the inside and outside edges being provided with a reflective surface.
US09290041B2 Streamlined tailfin for bicycle wheel spoke
A streamlined tailfin rotatably attached to a bicycle wheel spoke reduces drag by swiveling as a wind vane in both headwinds and crosswinds.
US09290040B2 Methods for manufacturing panels and panel
A method for manufacturing panels of the type having at least a substrate and a printed decor with a relief provided on the substrate involves printing, whether or not by the intermediary of primer layers, at least a portion of the decor onto the substrate and forming the relief. The relief is formed at least partially after the portion of the decor has been printed on the substrate.
US09290039B2 Production method of workpiece and workpiece with three-dimensional pattern
A production method of workpiece is provided. First, an adhesive layer is applied on a workpiece. The adhesive layer is impressed by a mold, so that the adhesive layer forms a three-dimensional pattern. A first curing process with a first irradiating energy is performed on the adhesive layer. The workpiece is punched after the first curing process is performed on the adhesive layer, so that the workpiece forms a three-dimensional workpiece. A second curing process with a second irradiating energy is performed on the adhesive layer after the workpiece is punched, wherein the second irradiating energy intensity is higher than the first irradiating energy intensity.
US09290038B2 Heat transfer labels and method of making same
A substantially halo-free heat transfer label is made using a 3D printing method. The heat transfer label includes a graphic layer and an adhesive layer. The adhesive layer is printed using a 3D printing method, which provides a substantially reduced adhesive halo when compared to heat transfer labels including a screen printed adhesive layer or that printed via other conventional printing methods.
US09290035B2 Refillable notebook with release mechanism
A binding mechanism assembly for binding a sheet item, the binding mechanism assembly including a backing member having an upper surface, and a binding member directly or indirectly coupled to the backing member. The binding member includes a protrusion shaped and located to protrude through a hole of a sheet item to be bound thereto. The binding member further includes a generally flexible flange that is manually movable into engagement with the protrusion to form a generally closed loop and thereby bind the sheet item thereto. The loop is rotatable relative to the backing member from a first position in which the loop is generally located above the upper surface to a second position wherein at least part of the loop is located below the upper surface. A release mechanism is provided for opening the loop.
US09290023B2 Printing apparatus, control method, and storage medium
A printing apparatus according to the present invention includes a conveying unit conveying a printing medium, a printing unit, a cutting unit cutting the printing medium in a direction perpendicular to a conveying direction of the printing medium and a control unit. The control executes a test operation. The test operation includes printing a mark and cutting the printing medium while conveyance of the printing medium is stopped.
US09290020B2 Printing system with span extension member
A printing system including a plurality of printheads for printing on a web of media traveling along a web transport path, at least one of the printheads being configured to print at first and second print lines. A plurality of web transport rollers guide the web of media along the web transport path. At least some of the plurality of web transport rollers are constrained to have a roller circumference that is substantially equal to an integer fraction of a span of the web of media along the web transport path between two successive print locations in successive print heads. A span extension member provides an increased span of the web of media between the first and second print lines in a particular printhead such that the increased span is an integer multiple of the roller circumferences of the constrained web transport rollers.
US09290016B2 Printing system
A printing system is disclosed which comprises an image forming station 12 at which an ink that includes an organic polymeric resin and a coloring agent is applied to an outer surface of an intermediate transfer member 10 to form an ink image, a drying station 14 for drying the ink image to leave a residue film of resin and coloring agent; and an impression station 16 at which the residue film is transferred to a substrate. The intermediate transfer member 10 comprises a thin flexible substantially inextensible belt and the impression station 16 comprises an impression cylinder 20 and a pressure cylinder 18 having a compressible outer surface for urging the belt against the impression cylinder to cause the residue film resting on the outer surface of the belt 10 to be transferred onto a substrate passing between the belt 10 and the impression cylinder 20 during engagement with the pressure cylinder. The belt 10 has a length greater than the circumference of the pressure cylinder 18 and is guided to contact the pressure cylinder over only a portion of its length.
US09290015B2 Inkjet recording method and printed material
The object of the present invention is to provide an ink jet recording method where it is possible to obtain a printed material where the elution amount (migration) to the outside of the components in a cured ink composition is small and there is little character blurring, and a printed material. The ink jet recording method of the present invention includes a step of ejecting an ink composition which contains 3-methyl pentanediol diacrylate of 30 mass % or more with respect to the total ink composition from an ink jet head onto a support, and a step of irradiating active rays in an atmosphere where the oxygen partial pressure is 0.10 atm or less to cure the ink composition.
US09290014B2 Inkjet recording apparatus
An inkjet recording apparatus 1 which is able to print high quality images by changing ultraviolet intensity in the sub-scanning direction. The inkjet recording apparatus 1 includes a carriage moving back and forth in the main scanning direction, inkjet heads 5 mounted on the carriage 4 for discharging ink droplets, and an ultraviolet irradiator 6 mounted on the carriage 4 for irradiating ultraviolet rays. The ultraviolet irradiators 6 include a plurality of UVLEDs 63 provided on a center of a bottom surface of a concave portion 62 of the irradiators 6 and arranged in the sub-scanning direction, and a plurality of partition walls 64 provided between the UVLEDs 63 and having a flat plate shape extended in the main scanning direction. The ultraviolet intensity in the sub-scanning direction can be changed by controlling each UVLED 63.
US09290013B2 Inkjet recording apparatus
An inkjet recording apparatus 100 is provided with a fabric feeding section A having a medium for recording 1 composed of a fabric, an inkjet section B for performing inkjet recording on the medium for recording 1 fed from the fabric feeding section A to form a recorded medium 1a, and a treating section C1, C2 having a drying section 11, 21 for drying the recorded medium 1a and a collecting section 12, 22 for collecting the dried recorded medium, the drying section 11, 21 and the collecting section 12, 22 being integrated with each other, where the treating section C1, C2 is attachable to and detachable from the inkjet section B.
US09290011B1 Printer
A printer includes a cassette mounting portion, a feed portion, a print head, a mechanical sensor, and a sensor holding portion. The cassette mounting portion is configured such that a tape cassette can be removably mounted therein. The tape cassette includes a tape and an indicator portion indicating a type of the tape. The feed portion is configured to feed, along a specified feed path, the tape contained in the tape cassette mounted in the cassette mounting portion. The print head is configured to perform printing on the tape fed by the feed portion. The mechanical sensor is configured to detect the type of the tape indicated by the indicator portion. The mechanical sensor includes a plurality of switch terminals and a switch holding portion. The sensor holding portion is configured to hold the mechanical sensor and to be moved between a first position and a second position.
US09290010B2 Method and apparatus for fractal identification
A method and system for applying and reading a fractal image to and from a plurality of objects to act as an identification label is provided. The system includes a printer for printing a fractal pattern to the plurality of objects and a reader for reading the printed fractal pattern. Such a fractal image is robust to printing and imaging difficulties and inconsistencies, and is difficult to copy, thus defending against counterfeiting.
US09290007B2 Thermal transfer image receiving sheet and image forming method
The present invention is to provide a thermal transfer image receiving sheet which is able to provide excellent printing sensitivity and prevent the generation of poor image quality in high density areas and folded lines even during high speed printing, and an image forming method for forming an image on the thermal transfer image receiving sheet. Presented is a thermal transfer image receiving sheet containing a substrate and, on at least one surface of the substrate, a composite porous layer containing a thermoplastic resin, and a dye receiving layer in this order from the substrate, wherein the composite porous layer contains a porous core layer and non-porous skin layers layered on both surfaces of the porous core layer; a total thickness of the non-porous skin layers is 5 to 15% of a whole thickness of the composite porous layer; and a density of the composite porous layer is 0.65 to 0.74 g/cm3.
US09290001B2 Liquid container, liquid consuming apparatus, liquid supply system and liquid container unit
A liquid container includes an ink chamber containing an ink to be supplied via a tube to a liquid ejecting head consuming the ink; an outlet port from which the ink contained in the ink chamber flows to the tube side; an injection port through which the ink can be injected into the ink chamber; and an air intake port taking air into the ink chamber from a further vertically upper position than a liquid level of the ink when the ink is contained in the ink chamber. If the ink equal to 5% of containing capacity containable in the ink chamber flows from the outlet port, the liquid container has an area where a fluctuation range of the liquid level of the ink inside the ink chamber becomes 5% or less of the cubic root of the containing capacity.
US09289998B2 Recording apparatus and multi-function printer
A recording device includes a main body case that is arranged inside a recording head which ejects ink to paper, and an ink storing device that stores the ink to be supplied to the recording head and is attached to the outer side surface of the main body case through a screw member. When upward external force is added from the ink storing device, the main body case includes a reception section which can accept the external force.
US09289995B2 Liquid ejecting apparatus
A liquid ejecting apparatus, including: a liquid ejecting head having an ejection surface; a platen; a capping mechanism including: a first member opposed to the ejection surface with the platen interposed therebetween when image recording is performed; and a second member disposed around the head so as to cooperate with the first member to hermetically close an ejection space; a distance adjusting mechanism for adjusting a distance between the ejection surface and the first member; a platen moving mechanism for moving the platen between the facing position and a non-facing position at which the platen does not face the ejection surface; and a controller configured to control the platen moving mechanism such that the platen is located at the non-facing position and controls the distance adjusting mechanism such that the distance is equal to a members-abuttable distance that allows the second and first members to abut on each other.
US09289994B2 Ink jet head and ink jet printer
A channel-structure has first to third nozzle-rows for first-ink, and first and second nozzle-rows for second-ink. Between the first nozzle-row for the first-ink and the first nozzle-row for the second-ink, and between the second nozzle-row for the first-ink and the second nozzle-row for the second-ink, each nozzle is located in the same position. The third nozzle-row for the first-ink is located in a different position with respect to the first and second nozzle-rows. Either the first and the second nozzle-rows for the second-ink are arranged between the first and second nozzle-rows for the first-ink, or the first and second nozzle-rows for the first-ink are arranged between the first and second nozzle-rows for the second-ink. A distance between the first nozzle-row for the first-ink and the first nozzle-row for the second-ink is equal to a distance between the second nozzle-row for the first-ink and the second nozzle-row for the second-ink.
US09289993B2 Liquid ejecting apparatus
A liquid ejecting head includes: a nozzle surface which is a two-dimensional imaginary surface, and which includes first areas which are staggered in a plan view and second areas which are staggered in the plan view, wherein a nozzle is disposed in each of the first areas in the plan view, a recess is disposed in each of the second areas in the plan view, and the recess is recessed with respect to the nozzle surface and includes a bottom.
US09289990B2 Inkjet head
An inkjet head may include a nozzle hole; a pressure chamber; and a piezoelectric device disposed on the side opposite to the nozzle hole. A cross-sectional shape of the pressure chamber may include a circular-arc-shaped side wall portion and linear side wall portions connected with two ends of the circular-arc-shaped side wall portion on the side opposite to the supply side, the distance between the linear side wall portions gradually decreasing toward the side opposite to the supply side. The piezoelectric device may include a displacement portion that causes the pressure change inside the pressure chamber, and an electrode connection portion electrically connecting the piezoelectric device and an electrode. A cross-sectional shape of the displacement portion may include a circular-arc-shaped portion and has a smaller cross section than a corresponding cross section of the shape formed by the circular-arc-shaped side portion.
US09289989B2 Liquid ejecting head and liquid ejecting apparatus
Provided is a liquid ejecting head including a liquid ejection surface through which liquid is ejected, a head casing body in which the liquid ejection surface is provided on one surface, an atmosphere opening port which is open in an outer-side wall surface of the head casing body, a first space portion which communicates with the atmosphere opening port in the head casing body, and a second space portion which communicates with the first space portion through a connection path. The first space portion reserves liquid entering through the atmosphere opening port.
US09289987B2 Heating element for a printhead
An exemplary embodiment of the present invention provides for a fluid ejection device. The fluid ejection device includes a substrate, a conductive layer, a resistive layer, and at least one upper layer. The conductive layer is disposed on the substrate and an outer perimeter and an inner region thinner than the outer perimeter. The outer perimeter includes conductive elements spaced apart from one another. The resistive layer includes an outer resistive portion overlying the conductive elements and a central resistive portion lying on top of a raised bridge of the substrate, wherein the width of the raised bridge is substantially greater than the width of the central resistive portion. The at least one upper layer defines a boundary of a fluid chamber, and the boundary is aligned vertically above a border of the central resistive portion.
US09289980B2 Power source control device for inkjet head and inkjet printing apparatus
The device and method handles increases in power consumed by an inkjet head. When greater-than-specified electric power is being input from both the first input section and the second input section, the control section controls the state of connection so as to prioritize connection of the second power source to the inkjet head driving system over the first power source.
US09289976B2 Automated high performance waveform design by evolutionary algorithm
A method can include receiving an initial waveform and generating, testing, and evaluating the performance of an initial child set of waveforms based on an initial parent set of waveforms from the initial waveform. The method can also include determining whether a termination condition has been met based on the evaluating and, if so, providing an optimized waveform. If the termination condition has not been met, the method can also include generating subsequent child sets of waveforms based on the previous child set(s).
US09289974B2 Printhead control systems and methods for controlling a printhead
A printhead control system comprises a voltage supply control module to selectively supply an operating voltage to a printhead, and the voltage supply control module is configured to receive a first and a second control voltages, and to disconnect the supply of operating voltage to the printhead at least when the first and second control voltages have the same logical level.
US09289973B2 Transfer decorating machine and method for transferring an image
A transfer decorating machine that utilizes powdered material or granules comprises: a mobile rest surface (10), on which the objects to be decorated are translated according to a predetermined direction; a device for the application of a decoration, operating above the mobile rest surface (10) and provided with a mobile transfer belt (3), which is a closed loop between movement rollers (2, 20) having mutually parallel axes, and serves the function of receiving a decoration realized with powdered material or granules (9) and then transferring it on objects to be decorated. Said device comprises a first unit (100) suitable for composing a decoration on the transfer belt (3) and a second unit (200) that carries out the transfer of the decoration from the transfer belt (3) onto an object to be decorated. The transfer belt (3) is commanded to move in a direction concordant with that of the mobile rest surface (10). The second unit (200) comprises a section located in the lower part of the transfer belt (3) that has the external side thereof facing downwards and facing, at a predetermined distance, a surface to be decorated (11) of an object lying on the mobile rest surface (10). This section extends between a curved surface of an abutment (17, 2) and a movement roller (20). There are means operating correspondingly on the internal side of the said section of the transfer belt (3) to direct jets of air towards it, said jets of air generating a situation of turbulence.
US09289972B2 Impression mediums, printing system having impression medium, and method thereof
An impression medium usable with an impression member of a printing system is disclosed. The impression medium includes a top layer and a backing layer disposed between the top layer and the impression member.
US09289970B2 Apparatus and method for peeling protective film and method for fabricating stereoscopic image display device
A film member attached to the outer peripheral surface of a cylindrical plate is fixed by a peeling roller and a clamp of a peeling unit and peeled from the cylindrical plate by moving the peeling unit, and the intervals between each of the peeling units and the outer peripheral surface of the cylindrical plate are same so that the contact portions of the peeling rollers are variable.
US09289960B2 Dual shuttle press
A heat press can include a frame, a first lower platen, a second lower platen, an upper platen, a press mechanism, a shuttle mechanism, and a heating element. The lower platens can be supported by the frame. The press mechanism can be coupled to the upper platen and operable to move the upper platen between open and closed positions. In the open position, the upper platen can be spaced apart from the lower platens by a greater distance than when in the closed position. The shuttle mechanism can be supported by the frame and can move the press mechanism linearly between a first position and a second position. In the first position, the upper platen can be located above the first lower platen. In the second position, the upper platen can be located above the second lower platen. The heating element can be configured to heat the upper platen.
US09289954B2 Method of ring-shaped structure placement in an eye-mountable device
Example eye-mountable devices and methods for fabricating eye-mountable devices are described. A method may include applying a first amount of polymerizable material to a ring-shaped structure, where the ring-shaped structure comprises at least one sensor configured to detect an analyte. The method also may include positioning the ring-shaped structure with the first amount of polymerizable material applied thereto in a mold, where the mold is configured to form an eye-mountable device. Further, the method may include applying pressure on the ring-shaped structure in the mold while curing the first amount of polymerizable material. Still further, the method may include adding a second amount of polymerizable material to the mold with the ring-shaped structure therein, and curing the second amount of polymerizable material to form an over-molded polymer layer such that the ring-shaped structure is at least partially enclosed in the eye-mountable device.
US09289951B2 Moulded product for automotive panels
Composite moulded product comprising of at least one polyamide-reinforcement layer consisting of a polyamide matrix and reinforcement fibers, characterised in that the polyamide-reinforcement layer is porous due to the consolidation using a pressurised steam process.
US09289949B2 Optimized cross-ply orientation in composite laminates
A composite laminate has a primary axis of loading and comprises a plurality resin plies each reinforced with unidirectional fibers. The laminate includes cross-plies with fiber orientations optimized to resist bending and torsional loads along the primary axis of loading.
US09289948B2 Receptacle with mount feature
A method for forming a receptacle may include providing a mold having a forming surface and a recessed area defining part of the forming surface, the mold having sections that may be separated to open the mold and closed together to close the mold. A molten plastic parison may be provided into the mold when the mold is open, the mold may be closed and the parison may be expanded against the forming surface so that a portion of the parison enters the recessed area. The portion of the parison within the recessed area may be formed by moving a secondary forming feature relative to the mold and parison to define a mount feature.
US09289947B1 System for air cleaning precision rails in three-dimensional object printing systems
A system for cleaning precision rails of a three-dimensional object printer has been developed. The printer includes a track having a pair of precision rails positioned beneath a printing station having an ejector head configured to eject drops of material onto a substrate of a cart that moves along the rails. An air source with a duct is configured with a slot to direct an air flow onto one of the precision rails to prevent dust or other airborne particles from collecting on the precision rail.
US09289943B2 Apparatus and method for attaching an RF tag to a sponge item
The subject matter discloses a method of attaching a tag to a disposable item such as a sponge, the method comprising obtaining a tag and a disposable item; attaching the tag to the disposable item using an adhesive material. The adhesive material is cured by ultraviolet radiation. The method also comprises applying the ultraviolet radiation on the tag attached on the disposable item. The tag may be an RE tag.
US09289939B2 Apparatus and method of shaping plastics material pre-forms with separate flow paths for blowing air and control air
An apparatus for shaping plastics material pre-forms into plastics material containers has a movable carrier on which are arranged a plurality of shaping stations for shaping the plastics material pre-forms into the plastics material containers. Each shaping station has a stressing device which acts upon the plastics material pre-forms for the expansion thereof with a gaseous medium, and a pressure preparation device which prepares the gaseous medium. The pressure preparation device is arranged in a stationary manner and supplies the shaping stations with the gaseous medium for the expansion of the plastics material pre-forms by way of at least one connection line. A distribution device is provided which distributes the gaseous medium from the pressure preparation device shaping stations. A control air line supplies the valve device with a control gas, and a blowing air line supplies the shaping stations with the gaseous medium, are separate from each other at least downstream of the distribution device in a flow direction of the gaseous medium.
US09289932B2 Heating cylinder protection cover for an injection molding machine
A heating cylinder protection cover that covers an entire circumference of a heating cylinder of an injection molding machine is configured from a plurality of protection cover members. Cutouts for cable passing section formation are provided in one or both of a pair of cover members joined to each other among the plurality of protection cover members. A cable is drawn out to the outer side of the heating cylinder protection cover through the cutouts for cable passing section formation.
US09289929B2 Moulding arrangement and a method for producing an article using the moulding arrangement
A molding arrangement serves for molding articles at each stroke of an injection-molding machine in which an injection mold is mounted. The articles are composed of components made of different materials in cavities formed in the injection mold, with each cavities corresponding to the shape of a component whereby identical cavities are separated by angular distances and placed at equal distances from a central axis of the injection mold and parts of the cavities are formed in a separately movable section of the movable mold half. The injection molding arrangement includes an operation part for displacing the section to-and-fro between closed and open positions of the injection mold and in open positions to turn the section about the central axis angles corresponding to the angles between the cavities to form whole cavities in the injection mold in closed position.
US09289928B2 Method for coating a molded part
In a method for coating a molded part (1), in particular a molded part produced by injection molding, the molded part (1) is arranged in a cavity (2) of a molding tool (3), wherein a partial cavity (4) between the molded part (1) and a first molding-tool half (5) of the molding tool (3) remains when a closing force (F) is applied to the molding tool (3) at a first closing-force level. A coating mass (6) is introduced into the partial cavity (4) and the coating mass (6) is cured/cross-linked. The closing force (F) of the molding tool (3) is increased during the curing/cross-linking of the coating mass (6), wherein the increase in the closing force (F) causes a volume reduction of the partial cavity (4) due to elastic deformation of the molding tool (3) and/or elastic deformation of the molded part (1).
US09289921B2 Method of forming single-mode polymer waveguide array connector
A method of forming a single-mode polymer waveguide array connector that provides precise alignment of a plurality of cores of polymer waveguide arrays with respect to an absolute reference position, such as a guide pin hole in a ferrule, when the polymer waveguide array connector is connected to another polymer waveguide array connector or provides precise alignment of a plurality of cores of a polymer waveguide array and a fiber array with respect to the absolute reference position when the polymer waveguide array connector is connected to a single-mode fiber array connector. A plurality of cores of single-mode polymer waveguide arrays or single-mode fiber arrays is precisely aligned with each other. In addition, there is provided a combination of a plurality of molds, e.g., a first mold (A) and a second mold (B), used in a plurality of processes in a specific method.
US09289917B2 Method for 3-D printing a pattern for the surface of a turbine shroud
A method of making an article of manufacture is provided and includes the steps of spraying a first coating onto a substrate, and depositing a second coating on the first coating by 3-D printing a material disposed in a pattern. The pattern includes ridges disposed at a base surface of a turbine part. Each ridge defined by first and second sidewalls, each sidewall having a first and second end. The ends extend from the base surface, the sidewalls slope toward each other until meeting at second ends of respective first and second sidewalls defining a centerline and a top portion of the ridge. The sidewalls are inclined with substantially equal but opposite slopes with respect to the base surface. The ridges correspond to a back portion of a turbine bucket and are oriented at a first angle with respect to an axis of rotation of the bucket.
US09289910B2 Method of processing ridge of cutting edge and instrument with processed ridge of cutting edge
Two surfaces forming a cutting edge and a ridge of a cutting edge existing along the boundary between the two surfaces intersecting with each other are irradiated with a gas cluster ion beam at the same time, the maximum height of the profile of the two surfaces being equal to or smaller than 1 μm. A facet is newly formed on the ridge of the cutting edge by performing the irradiation with the gas cluster ion beam in such a manner that the two surfaces are not perpendicularly but obliquely irradiated with the gas cluster ion beam, and at least a part of the ridge of the cutting edge is perpendicularly irradiated with the gas cluster ion beam.
US09289909B2 Razor cartridge and mechanical razor comprising such a cartridge
A razor cartridge that includes a housing, at least one support, movably mounted to the housing along a first degree of freedom, the support including a lower portion having an extremity, an upper portion having an extremity, and a bent portion intermediate the lower and upper portions, the portions having parallel first and second faces. The razor cartridge also includes a razor blade having a cutting edge and a fixation portion fixed on the second face of the upper portion of the support, where the extremities are rounded along a whole length of the support extending in a longitudinal direction.
US09289907B2 Open cutter for a foil type shaver and method for fabricating the open cutter
An open cutter for a foil type shaver includes a plurality of arch-shaped cutting strips formed by bending a metal plate formed with alternating parallel slots and cutting strips. A plurality of spaced apart protruding cutting edges having a first acute cutting angle is formed along two opposite sides of the cutting strips. A plurality of recessed cutting edges having a second acute cutting angle is formed between the plurality of protruding cutting edges. The protruding cutting edges of one cutting strip are facing the recessed cutting edges of an adjacent cutting strip, thereby generating continuous hair-lifting and hair-cutting actions as the open cutter is driven in oscillating directions by a motor. A method for fabricating the open cutter is also disclosed.
US09289903B1 Knife draw assembly
A removable knife draw assembly for a folding knife. The removable knife draw assembly may be structured as a clip assembly and include a modified clip and other components which can be used in various combinations, including one or more of a clip draw tab, a body draw tab, a height adjuster, a tensioner, a tensioner pad, and a platform. The removable knife draw assembly provides structures that allow a user to engage and use the knife in an efficient manner. In this configuration, the removable clip assembly provides a removable clip to adjustably position the folding knife to a pocket, holster or other container, the removable clip having one or more of a clip draw tab to remove the knife from the container, a height adjuster to position the folding knife in the container and a tensioning mechanism to secure the folding knife in the container with the proper resistance.
US09289900B2 Calibration tool for a delta robot
A jig for calibrating a Delta robot fixes the longitudinal axes of drive arms to be parallel. With this configuration, the jig always fixes the drive arms at the same reference angle no matter what the drive arm length is.
US09289896B2 Securable and collapsible work station
A work station includes tool containing or supporting features as well as workbench features, such as a work surface and work back. The work station is preferably mobile, permitting it to be moved or transported. In addition, the work station is preferably collapsible and securable. In one configuration, the work station has a work bench portion which can be raised or lowered relative to a base portion, wherein in the lowered position, the base portion is positioned in an interior space of the work bench portion.
US09289895B1 Adapter for extending a tool handle
An adapter for mounting a tool on an extension handle, and the adapter may be elongated with a proximal end and a distal end with a longitudinal axis extending between the distal and proximal ends. The adapter may comprise a socket portion located toward the proximal end and being configured to mount on the extension shaft, and a mounting portion located toward the distal end and being configured to removably receive a portion of the handle of the tool. The mounting portion may include a mounting assembly that comprises an elongated spine member extending substantially along the longitudinal axis of the adapter, and a pair of mounting structures positioned on the spine member at longitudinally spaced positions on the spine member. Each of the mounting structures may comprise a loop of adjustable size.
US09289879B2 Hinge assembly for an angle grinder dust shroud
A hinge assembly for attaching a door member to a main structure is provided. The hinge assembly, in an embodiment, includes a first hinge member securely attached to one of the door member or the main structure; a second hinge member securely attached to the other of the door member or the main structure and rotatably engaging the first hinge member; and a cam/spring assembly configured to bias the door member into an open or a closed position with respect to the main structure.
US09289873B2 Abrasive cutting machine
An abrasive cutting machine includes a housing and a cutting arm on which a cutting tool is accommodated on the end side. The cutting tool is driven via a belt by an engine of the abrasive cutting machine, and the housing encompasses a fan chamber for accommodating a fan wheel by which an air flow is provided. A belt chamber for accommodating the belt is embodied in the cutting arm, with improved durability of a belt, in particular the dust exposure of the belt for power transfer from the engine to the cutting tool. Provision is made between the fan chamber and the belt chamber for an air duct, through which at least a part of the air flow, which is created by the fan wheel, reaches from the fan chamber into the belt chamber, so as to apply a sealing air flow to the belt chamber.
US09289872B1 Multi-wheel grinder tool
A multi-wheel grinder tool provides multiple grinding wheels and polishing pads arranged in a single row, and moving along an edge of a stone slab. The tool is effective for increasing the longitudinal surface area for grinding across the edge of a stone slab. The wheels rotatably grind the edge of the slab while simultaneously moving along the longitudinal axis. As the wheels pass along the longitudinal axis, the pad rotatably engage the edge. The edge of the slab is in contact with each pad from all the wheels. A control wheel is powered by a motor via a gear system and a control axle. Outer wheels are in rotatable communication with the control wheel and run counter to each other. By using multiple wheels, grinding is expedited. The wheels have pads with successive grits. A first pad has course grinding grits. A last pad has fine polishing.
US09289868B2 Adjustable angle workpiece positioning disc
An adjustable angle workpiece positioning disc includes a partial quarter section defining confronting and intersecting surfaces that form an orthogonal angle therebetween. A central through hole located at the center of the disc. Disc coordinate axes originated at the center of the central through hole. Pluralities of angle through holes are arrayed about the central through hole. The disc is mountable to the plate by doweling the central through hole with a dowel pin receiving hole and by doweling one angle through hole with a dowel pin receiving hole in accordance with a desired revolved angle between the disc coordinate axes and the plate coordinate axes.
US09289865B2 Fixturing apparatus
A method to manufacture a fixturing apparatus, the method including forming a first assembly and a second assembly, wherein both the first assembly and the second assembly comprise a bottom, a first lip extending outwardly from the bottom, an opposing second lip extending outwardly from the bottom, a first side wall extending outwardly from the bottom and connecting a first end of the first lip and a first end of the second lip, a second side wall extending outwardly from the bottom and connecting a second end of the first lip and a second end of the second lip, and a plurality of locking teeth extending outwardly from the bottom, wherein the plurality of locking teeth are disposed between the first lip, the second lip, the first side, and the second side; and forming the fixturing apparatus by attaching the first assembly to the second assembly.
US09289862B2 Device for sealing a delivery fluid system and method
A method for permanently repairing a fluid delivery system which may be above ground, subterranean, in and under concrete, or within a wall structure. The method comprises disconnecting the source and the discharge portions of the fluid delivery system. A resilient moldable tubing is threaded through the fluid delivery system. The first end of the tube is secured to the first end of the portion of the fluid delivery system. The second end of the tube is next secured to the second end of the portion of the fluid delivery system. The resilient tubing is then filled with heated fluid and pressurized to mold the tubing to the inside diameter of the fluid delivery system. The fluid is cooled to set the tube to the inside diameter of the fluid delivery system, and then drained before reconnecting the source and discharge portions of the fluid delivery system.
US09289861B2 Device for recontouring a gas turbine blade
Device (1) for recontouring a gas turbine blade (2), comprising: at least one support (6a, 6b) configured to rest on an edge (3a) of the gas turbine blade (2) during the recontouring, at least one side bearing (5a, 5b) configured to rest on the suction- and/or pressure side (3b, 3c) of the gas turbine blade (2) in a lateral direction (7) during the recontouring, a machining unit (4) via which the gas turbine blade (2) is cutting machined in a machining direction (8) along the edge (3a), wherein the machining unit (4) can be displaced perpendicularly to the machining direction (8).
US09289860B2 Jig used for repairing pin-coupling component and method using the same
A jig used for repairing a component having a tang with a hole is comprised of: a main body defining a standard line; a positioning pin detachably attached to the main body and so dimensioned as to fit in the hole to make an axial center of the hole be aligned with the standard line; and a clamp so structured as to catch hold of the tang to secure the component to the main body in a state where the axial center is aligned with the standard line.
US09289854B2 Automated superalloy laser cladding with 3D imaging weld path control
Superalloy components, such as service-degraded turbine blades and vanes, are clad by laser beam welding. The welding/cladding path, including cladding application profile, is determined by prior, preferably real time, non-contact 3D dimensional scanning of the component and comparison of the acquired dimensional scan data with specification dimensional data for the component. A welding path for cladding the scanned component to conform its dimensions to the specification dimensional data is determined. The laser welding apparatus, preferably in cooperation with a cladding filler material distribution apparatus, executes the welding path to apply the desired cladding profile. In some embodiments a post-weld non-contact 3D dimensional scan of the welded component is performed and the post-weld scan dimensional data are compared with the specification dimensional data. Preferably the welding path and/or cladding profile application are modified in a feedback loop with the pre- and/or post-welding 3D dimensional scanning.
US09289853B2 Laser beam applying apparatus
A laser beam applying apparatus includes a laser beam oscillating unit, a focusing lens, and a diffractive optic element provided between the laser beam oscillating unit and the focusing lens for defining the spot shape of the laser beam oscillated by the laser beam oscillating unit. A zeroth-order light removing unit removes zeroth-order light emerging from the diffractive optic element and leaves first-order light whose spot shape has been defined by the diffractive optic element and the focusing lens. A first prism has an incident surface and an emergent surface inclined with respect to the incident surface. A second prism has a zeroth-order light reflecting surface for reflecting the zeroth-order light and a first-order light emerging surface from which the first-order light emerges. A damper absorbs the zeroth-order light reflected on the zeroth-order light reflecting surface of the second prism.
US09289849B2 Apparatus for friction stir welding
One aspect of the disclosure relates to a friction stir welding apparatus. The friction stir welding apparatus includes a spindle housing and a pin tool concentric with an axis and rotatable relative to the spindle housing about the axis. The friction stir welding apparatus also includes a first shoulder not substantially rotatable relative to the spindle housing about the axis and a second shoulder not substantially rotatable relative to the spindle housing about the axis. The pin tool is rotatable relative to the first shoulder and the second shoulder.
US09289845B2 Metal deposition of exterior members in oil field tubulars
Layered metal deposition by fusion thereof onto a surface of an engineered structural member, without degrading structural performance. The net shape of an exterior member is defined, including a fusion contact area. The structural member is preheated below its maximum operating temperature. An energy beam and feedstock are directed to a feed point in the fusion area, thereby forming a molten puddle fusing the materials together. The feed point is moved relative to the structural member, thereby advancing the molten puddle of presently fed feedstock and rapidly solidifying previously fed feedstock. The energy beam power is modulated to control the size of the molten puddle so as not to exceed a predetermined depth of penetration of the fusion region into the structural member. Advancing the feed point sequentially fuses feedstock into the defined net shape on the structural member.
US09289844B2 Power supply chassis
A welding power supply includes a housing and a one-piece chassis. The one-piece chassis is coupled to the housing and configured to be enclosed within the housing. Moreover, the one-piece chassis is configured to be selectively removable from the housing and the one-piece chassis is configured to have multiple components coupled thereto. The components include one or more transformers, a fan blade, one or more rectifiers, one or more inductors, and control circuitry.
US09289838B2 Guide roller
Disclosed is a guide roller wherein bearings are held in a housing, and liquid mixed with abrasive grains is prevented from entering the interior of the housing through a small hole, thereby improving service life. The guide roller is configured to comprise a housing wherein the bearings are held in the housing, and the housing has a shaft hole wherein a support shaft is inserted that is installed upon the bearings. The shaft hole is formed to have a tapered wall, and the diameter of the hole decreases continuously toward the interior of the housing.
US09289830B2 Cutting tool and cutting insert
A cutting tool has a recess for receiving a cutting insert having a clamping depression on the rake face. The cutting insert is held in the carrier tool by a clamping finger having a lug. The clamping finger being secured on the carrier tool via a clamping bolt so that when tightening the clamping bolt, the clamping finger pulls the cutting insert into the recess. A sickle-shaped engagement element engages into the clamping depression of the cutting insert being arranged on the lug. The clamping bolt has a clamping head overhanging its shank. The clamping head is seated on an angled locating surface of the clamping finger with respect to the axis of the clamping bolt, wherein said surface is arranged so compression force of the clamping finger on the cutting insert is enhanced. The lug has a clamping surface for bearing on the rake face of the cutting insert.
US09289828B2 Ball screw and a method for manufacturing the same
A ball screw has a nut formed with a helical ball rolling groove on its inner circumference. A screw shaft is formed with a helical ball rolling groove on its inner circumference. The screw shaft is inserted into the nut. A number of balls are rollably contained within a ball rolling passage formed by oppositely arranged helical ball rolling grooves of the nut and the screw shaft, respectively. The nut is made of case hardened steel. The ball rolling groove is formed by cutting and surface hardening, by vacuum carburizing hardening, without any after-processing.
US09289827B2 Mould assembly for a hot isostatic pressing process
This invention relates to a mould assembly for a hot isostatic pressing, HIP, process for fabricating a component, comprising: a first part which includes a shaped surface for forming a first surface of the component, the shaped surface having at least one recess; a second part arranged to move relative to the first part during the HIP process so as to compress a powder in-fill held therebetween, wherein the second part includes a formation configured to focus pressure toward the recess so as to aid consolidation of the powder in-fill at a distal end thereof.
US09289820B1 Apparatus and method for dispersing particles in a molten material without using a mold
An apparatus for dispersing particles within a molten material in a mold-less casting process comprises a primary electromagnet for generating an AC magnetic field and a secondary electromagnet adjacent to the primary electromagnet for generating an independent DC magnetic field. Each of the primary and secondary electromagnets comprises a coil and at least one of the electromagnets is positioned about a common longitudinal axis. A heat source may be positioned at a first end of the common longitudinal axis for forming a melt to be exposed to the AC and DC magnetic fields, and a particle injection device is positioned at one or more positions about the common longitudinal axis for injecting particles into the melt during magnetic field exposure. The apparatus does not include a solid body for containing the melt prior to solidification.
US09289819B2 Integral push fitting and valve with integral push fitting and method of manufacturing same
A push fitting for a valve includes a body having a longitudinal axis along which a fluid can flow, the body defining an opening at a first end of the body. A push fitting assembly at the first end of the body includes a housing. The housing includes a first end which is integrally formed within a wall of the opening at the first end of the body and a crimpable second end which extends longitudinally beyond the first end of the body. The housing also includes a crimpable material such that the second end of the housing is crimpable to capture elements of the push fitting assembly at the first end of the body.
US09289818B2 Device and method for reversibly gripping a bolt-shaped element, in particular a rivet mandrel
The device for reversibly gripping a rivet mandrel has a tension head with a mouthpiece sleeve and a clamping jaw sleeve axially movable in the mouthpiece sleeve and accommodating a plurality of clamping jaws. The clamping jaws reversibly grip the rivet mandrel during an axial displacement of the clamping jaw sleeve and the clamping jaws are furthermore held by an elastic holding element. The jaws are displaceable relative to one another independently of an actuation by the clamping jaw sleeve. This enables improved introduction and gripping of the rivet mandrel, especially for fully automated blind rivet operations, for example with blind rivet robots. Due to the elastic holding of the clamping jaws, wear on one side of the clamping jaws is avoided. Also, a controlled displacement of the clamping jaws independently of the clamping jaw sleeve is provided.
US09289816B2 Production method of leading edge reinforcement of fan blade
A production method uses ultrasonic forming but does not leave a bonding face exposed to the exterior in a final product. The production method of a leading edge member of a fan blade comprises the steps of causing superplastic forming by using a combination of a first mold having a flow path for gas and a second mold having a female mold to pressurize a plate member with the gas through the flow path to fit the plate member onto the female mold; bonding a backing with the plate member processed with the superplastic forming; and cutting out a periphery of the plate member to obtain a product shape.
US09289814B2 Spur toothing on a coupling element for transmitting torques
The invention relates to a spur toothing on at least one coupling element for transmitting torques about a rotational axis, said spur toothing axially engaging with a corresponding mating cutting. The face cutting is provided with teeth from a material of the coupling element that has been plastically shaped in an at least partially noncutting manner.
US09289809B2 Device and method for handling a metal strip
The invention relates to a device and a method for handling a metal strip. The device comprises a coiling device (110) with a coiling mandrel (112) for winding the metal strip to form a coil (200) on the coiling mandrel and a coil stripper car (120) with supports (124) for receiving the coil (200) from the coiling mandrel and removing the coil from the coiling device (110). In order to additionally secure the metal strip in the coiling device during the transfer from the coiling mandrel onto the coil stripper care and during a transport by means of the coil stripper car, a first hold-down arm (130) is provided for exerting a first hold-down force (F1) onto the outer circumference of the coil (200) in order to press the coil onto the supports of the coil stripper car.
US09289808B2 Coil laying head
A coil laying head comprising a rotor (14) having two or more conduits (1′), a selector tube (5) coaxially arranged with respect to the rotor (14) to guide a rolled product into one of the conduits (1′), a main control, connecting means between the main control and the rotor (14) for setting in rotation the rotor (14), a phase shifter system ((6,7,8,8′,9,10,11), including two nonmoving components ((10,),(11,)), an input component (7) connected to the main control, an output component (6) connected to the selector tube (5), a first group of side pinions (8′) meshed on the input component and on one of the nonmoving components and a second group of side pinions (8) meshing on the output component and on the other nonmoving components, connection means (9) connecting the first group of side pinions with the second group of side pinions to drive this latter in rotation according to the axis (X), angular phase shift adjustment device (12,) between the first and the second nonmoving component.
US09289803B1 Dispenser apparatus and method
A dispenser and procedure for disinfecting and cleaning air conditioner condensation drainage lines and other condensation drainage lines. The dispenser can be installed at any convenient location on any floor of a home or other building, regardless of whether the location is below, above, or at the same elevation as the inlet of the condensation drainage line. The dispenser includes a liquid pump for delivering an amount of treatment fluid into a treatment delivery line and an air pump for pushing the dose of treatment fluid through the treatment delivery line and into the condensation drainage line.
US09289798B2 Mask and mask assembly having the same
A mask having both ends supported on a frame when a tensile force is applied in a first direction includes: a mask main body unit having a band form extended in the first direction; a plurality of pattern units including a plurality of pattern slits extended and opened in the first direction and separately disposed in a second direction crossing the first direction, and disposed in the mask main body unit in the first direction; and a plurality of dummy units including a plurality of dummy slits separated from each other with the pattern units therebetween, disposed in the mask main body unit, extended and opened in the first direction, and separately disposed in the second direction.
US09289794B2 Microfluidic surface processing device and method
The present invention is notably directed to a microfluidic surface processing device including a microfluidic probe head with at least one aperture, on a face, including at least an outlet aperture; and a surface processing structure extending outward and perpendicular with respect to the face, the processing structure being further dimensioned and located with respect to the outlet aperture such that it can intercept a flowpath of liquid dispensed via the outlet aperture. The present invention is further directed to related apparatuses and methods.
US09289792B2 Aerosol generator
An aerosol generator has a vibratable plate with apertures therein and an annular piezo which causes movement of the vibratable plate. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab of the support member, also on its top side. There is a film of cured epoxy adhesive on the tab, providing excellent gripping force between the pin and the support. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
US09289790B2 Spray dryer absorber vibrator device and method
A spray dryer absorber operative for removing gaseous pollutants from a hot process flue gas and a vibrator device for removing accumulated deposits therefrom is provided. The spray dryer absorber includes a spray dryer chamber equipped with a plurality of dispersers and atomizers mounted at a roof of the spray dryer chamber. The vibrator device is operative to remove accumulated deposits from the spray dryer absorber and its components, such as its dispersers and atomizers, to avoid spray dryer absorber performance interference caused by such deposit accumulations.
US09289789B2 Trigger dispenser device
A trigger dispenser device (1) is for dispensing a liquid comprises a container (C) and a dispenser head (20). The head includes a frame (22) having a pressure chamber (24) and a secondary liquid aspiration duct (50), and an auxiliary body (2) attached to the frame (22). The auxiliary body is provided with a primary liquid aspiration duct (8) and an air aspiration chamber (4b). Between the frame (22) and the auxiliary body (2) a merger compartment (64) is formed and the air aspiration chamber (4b) surrounds the merger compartment (64) so as to seal it.
US09289784B2 Showerhead for generating micro air bubbles
A showerhead for generating micro air bubbles includes: a body including an inflow part disposed at one end thereof for supplying shower water, and a discharge part disposed at the other end thereof for discharging the shower water supplied through the inflow part; a bubble-generating part coupled to the discharge part, and including bubble-generating tubes which expand in the discharge direction of the shower water; a fluid regulator part for opening/closing a portion of the bubble-generating tubes; and a shower part disposed in front of the bubble-generating part, and including shower holes for discharging shower water. Since the bubble-generating part for generating micro air bubbles is disposed within the showerhead, shower water including micro air bubbles can be used by simply replacing a typical showerhead with the above-described showerhead.
US09289776B2 Milling device with adjustable milling operation
A milling device for performing a milling operation comprising a milling unit comprising a housing defining a milling chamber that can be filled with a material to be milled, a rotor assembly rotatably mounted in the housing, and a screen assembly for fractionating the material milled by the rotor assembly in movement and extending below the rotor assembly; and a drive unit adapted for controlling the movements of the rotor assembly relative to the screen assembly during the milling operation; wherein said drive unit is configured to produce an oscillating movement of the rotor assembly, the oscillating movement having an oscillation angle that can be varied during the milling operation when controlling the movements of the rotor assembly relative to the screen assembly. The milling device has improved milling efficiency.
US09289775B2 Discharge grate assembly
A discharge grate assembly for at least partially guiding slurry from a mill shell chamber toward a discharge trunnion thereof via a pulp lifter chamber. The discharge grate assembly includes a body having apertures for permitting the slurry to flow from the mill shell chamber into the pulp lifter chamber, and a shroud having a number of cover elements and a number of openings located at least partially therebetween. The shroud is movable relative to the body between an open position, in which the openings are at least partially aligned with at least preselected ones of the apertures to permit the slurry to flow therethrough into the pulp lifter chamber, and a closed position, in which the cover elements are at least partially aligned with at least predetermined ones of the apertures, to at least partially prevent the slurry flowing through the apertures back into the mill shell chamber.
US09289774B2 Apparatus for the pretreatment and subsequent conveying, plastification, or agglomeration of plastics
Disclosed is an apparatus for the processing of plastics, having a container with a rotatable mixing implement, where a conveyor is provided, with a screw rotating in a housing, wherein the imaginary continuation of the longitudinal axis of the conveyor in a direction opposite to the direction of conveying passes the axis of rotation, where, on the outflow side, there is an offset distance between the longitudinal axis and the radial that is parallel to the longitudinal axis, wherein on the internal wall area of the container, there is at least one bar-shaped deflector which is directed into the interior of the container, and the height profile of which decreases in the direction of rotation of the mixing implement, seen from above, and the angle included thereby, over its length, with a plane (E) perpendicular to the axis of rotation of the mixing implements is an acute angle (α).
US09289771B2 Impact mill having a rotor-positioning device
The mill includes a milling chamber (1) containing a rotor (2) provided with hammers (4), and at least one impact screen mounted pivotably with the aid of an adjusting jack in order to move the bottom end of the screen toward or away from the rotor so as to define, between the bottom end of the screen and the free end of the hammers, a spacing which determines a given particle size. The mill includes a device for positioning the rotor that includes indexing elements for positioning the end of one of the hammers as close as possible to the screen for adjusting the spacing. It includes a geared motor driving a pinion capable of engaging with a toothed wheel fixed in rotation to the rotor so as to rotate it from a rest state until one of the hammers is as close as possible to the screen.
US09289768B2 Apparatus for reducing variation in sample temperatures in a liquid chromatography system
Described is an apparatus for reducing a temperature variation of a liquid chromatography sample. A tray drive using at least one of linear or rotational motion moves a sample tray along a path inside a sample compartment of the liquid chromatography system. A control module coordinates the movement of the sample tray by the tray drive and the movement of a sample needle by a needle drive so that any sample in the sample tray can be injected into the mobile phase of the system during a sample load operation. The tray drive is also used to move the sample tray along the path during a temperature averaging period when no loading occurs. Differences in sample temperatures due to variations in the air temperature at different locations inside the sample compartment are reduced, leading to more accurate and repeatable chromatographic measurement results.
US09289766B2 Use of microfluidic systems in the detection of target analytes using microsphere arrays
The invention relates generally to methods and apparatus for conducting analyzes, particularly microfluidic devices for the detection of target analytes.
US09289762B2 Method for dosing a liquid using a pipette and a syringe, and pipette for operating a syringe for dosing a liquid
A method for dosing a liquid using a pipette with adjustable dosing step size and an indicating equipment and a syringe that can be operated using the pipette. The syringe is detachably connected to the pipette. The dosing step size is set, or the dosing step size set before is maintained. The dosing volume adjusted via the dosing step size is indicated. Liquid is aspirated into the syringe. Dosing steps are performed, counted and the number of performed dosing steps and/or the number of dosing steps still possible without refilling the syringe is determined and indicated. After performing the maximum number of dosing steps possible without refilling the syringe, either the syringe is detached, or the steps are performed again. The overall performed number of dosing steps with the set dosing step size is counted, and/or the number of dosing steps still possible without refilling is determined and indicated.
US09289761B2 Card waste storage mechanism
A multiple layer test card includes a waste channel to receive biological waste from an area of the test card utilized for testing biological samples. Multiple compartments in a waste layer of the card are separated from each other by a rib in the waste layer. A first compartment is positioned to receive biological waste from the waste channel. A pass is coupled between each adjacent set of compartments to pass biological waste and air between compartments. A vent in a last compartment provides an air exit from the card.
US09289758B2 Processes for producing chlorinated hydrocarbons and methods for recovering polyvalent antimony catalysts therefrom
The preparation of chlorinated hydrocarbons, such as pentachloropropanes, such as 1,1,1,2,3-pentachloropropane, from tetrachloropropanes, such as 1,1,1,3-tetrachloropropane, in the presence of a polyvalent antimony compound that includes a pentavalent antimony compound, such as antimony pentachloride, is described. Also described are methods for preparing optionally chlorinated alkenes, such as, tetrachloropropenes, from chlorinated alkanes, such as pentachloropropanes, in the presence of polyvalent antimony compound that includes a pentavalent antimony compound, as well as methods for recovering polyvalent antimony compounds from such processes.
US09289755B2 Synthesis of ZSM-5 crystals with improved morphology
Methods are provided for synthesizing crystals having a ZSM-5 framework structure from synthesis mixtures suitable for synthesis of ZSM-12 framework structure crystals in the absence of seed crystals with a ZSM-5 framework structure, such as in the absence of any seed crystals. For synthesis mixtures with a sufficiently high XO2:Y2O3 ratio, seeding a synthesis mixture with ZSM-5 seed crystals can result in production of pure phase ZSM-5 crystals with a new morphology. The morphology can include rod-like primary crystallites with a length of about 0.5 μm or less that are organized/aggregated into larger secondary crystal structures. The aggregation of the primary crystallites into a secondary crystal structure can allow for an unexpectedly large mesoporous surface area for the ZSM-5 crystals.
US09289754B2 Honeycomb structure
To provide a honeycomb structure capable of using as a catalyst carrier, which suitably functions as a heater by applying a voltage, and where a bonding layer is hard to break; and including a honeycomb segment bonded body where honeycomb segments are bonded by bonding layer, and a pair of electrode members disposed on side surface of the bonded body, wherein the electrode members is formed into a band shape, in a cross section perpendicular to the cell extending direction, the one electrode member is disposed on an opposite side across the center of the bonded body with respect to another electrode member, and in at least a part of the bonding layer, inorganic fibers made of an oxide are included in a porous body where particles of silicon carbide are bound with silicon in a state where pores are held among the particles.
US09289751B2 Method for producing composites of aluminum oxide and cerium/zirconium mixed oxides
The subject matter of the invention is a method for producing composites comprising aluminum oxide and cerium/zirconium mixed oxides, hereinafter referred to briefly as Al/Ce/Zr oxide composite(s) using boehmite and soluble cerium/zirconium salts. Al/Ce/Zr oxide composites produced in this way have an increased thermal stability.
US09289749B2 Polycondensation catalyst for producing polyester and production of polyester using the polycondensation catalyst
The invention provides a polycondensation catalyst for producing polyester by an esterification reaction or a transesterification reaction between a dicarboxylic acid or an ester-forming derivative thereof and a glycol, wherein the polycondensation catalyst comprises particles of a solid base having on the surfaces an inner coating layer of titanic acid in an amount of from 0.1 to 50 parts by weight in terms of TiO2 per 100 parts by weight of the solid base, and an outer coating layer either of an oxide of at least one element selected from aluminum, zirconium and silicon, or of a composite oxide of at least two elements selected from aluminum, zirconium and silicon on the surface of the inner coating layer in an amount of from 1 to 50 parts by weight per 100 parts by weight of the solid base.
US09289748B1 Treater regeneration
Disclosed are embodiments of a method of regenerating a desiccant in an off-line treater of a polyolefin production process. The method may include a heating phase followed by a cooling phase. The heating phase may involve use of a regenerating gas made from heating a treated a recycle stream of the polyolefin production process to regenerate desiccant in an off-line treater. The cooling phase may involve thermosyphoning the regenerating gas, nitrogen, an olefin-free diluent, or combinations thereof in a closed-convection loop of the off-line treater.
US09289747B2 Nanocomposites and their application as monolith columns
Novel materials for chromatographic separations, processes for their preparation, and separation devices containing the chromatographic materials. In particular, hybrid inorganic/organic monolith materials comprising a polymerized scaffolding nanocomposite (PSN), wherein the nanocomposite contains a scaffolding functionally capable of chemically interacting with a surface of a second material are described. The hybrid inorganic/organic materials have enhanced wall adhesion and increased resistance to shrinkage as compared to prior art monolith materials. The improved adhesion of the monoliths enable the preparation of capillary columns with an internal diameter (I.D.)≧50 μm.
US09289738B2 Nanoemulsion, method for its preparation and use
Nanoemulsions comprising an aqueous phase and a lipid phase, having a micelle size in the range from about 20 to about 900 nm and comprising melatonin as an active agent, are provided. The aqueous phase of such a nanoemulsion comprises a base, the lipid phase comprises one or more polyoxyethylene sorbitan esters, and the aqueous phase or the lipid phase, or both, further comprise ascorbyl palmitate. In addition, pharmaceuticals, cosmetics or foodstuffs comprising the nanoemulsions described herein and methods for making nanoemulsions described herein are also provided.
US09289727B2 Process for fabricating membrane filters, and membrane filters
The invention provides a process for fabricating a membrane filter that can stand up to filtration of nanometer-scaled fine particles or organic molecules, and a membrane filter having that filtration feature.Membrane filter 20 is disclosed. There is also the process for fabricating membrane filter 20 disclosed that is characterized by comprising the steps of mixing an aqueous solution containing a metal salt and an aqueous solution containing an alkali to prepare nanostrand solution 32 comprising a metal hydroxide, and filtrating nanostrand solution 32 through porous substrate 2 having pores to fabricate nanostrand sheet 3 comprising an accumulation of fibrous nanostrands on porous substrate 2 wherein the first pore formed between the nanostrands and extending through the nanostrand sheet from one surface side to another surface side has a maximum diameter of up to 5 nm.
US09289724B2 Flow reversing exhaust gas mixer
An exhaust mixing device for mixing an exhaust produced by an engine with a reagent exhaust treatment fluid that is dosed into the exhaust from a dosing module. The exhaust mixing device includes a decomposition tube having a first end and a second end. The first end of the decomposition tube is configured to receive the exhaust and the reagent exhaust treatment fluid. A flow reversing device is positioned at the second end of the decomposition tube. The flow reversing device includes a plurality of deflecting members that intermix the exhaust and reagent exhaust treatment fluid, and direct the exhaust and reagent exhaust treatment fluid in predetermined directions, wherein the flow reversing device reverses a flow direction of the exhaust back towards the first end of the decomposition tube.
US09289723B2 Exhaust system for saddle-ride type vehicle
An exhaust system for a saddle-ride type vehicle that can make it hard for the heat of a catalyst body to be transmitted to an external plate of a muffler. A catalyst body is installed in a muffler. An exhaust system has a tubular case covering the outer circumferential surface of the catalyst body along from the exhaust gas inlet to outlet of the catalyst body. The catalyst body is secured at its inlet-side end portion to one end portion of the case and the catalyst body is supported at its outlet-side end portion by the other end portion of the case. The case is supported at its outer circumferential surface by the front end portion of the muffler.
US09289719B2 Absorption and oxidation of NO in ionic liquids
The present invention concerns the absorption and in situ oxidation of nitric oxide (NO) in the presence of water and oxygen in ionic liquid compositions at ambient temperature.
US09289714B1 Device for adsorbing the hydrogen sulfide component of exhausted calibration gases
A portable and disposable device for adsorbing the hydrogen sulfide component of the calibration gases that would otherwise be released into the atmosphere during the calibration of such a detector includes: (a) an activated carbon bed having a configuration adapted to allow for a specified flow rate of the calibration gas, (b) an upstream and a downstream hydrated, particulate filter, (c) an upstream and a downstream hydrophobic filter, (d) a conduit having a configuration adapted to enclose and assemble the activated carbon bed, hydrated, particulate filters and hydrophobic filters; and wherein the hydrophobic filters and hydrophobic filters each have a configuration that is adapted to maintain the humidity level in the activated carbon bed above a set level.
US09289711B2 Plugged honeycomb structure
A plugged honeycomb structure including a honeycomb structure body, outflow side plugged portions, and inflow side plugged portions. A shape of cells in a cross section is a hexagonal shape. Among six corner portions of each of the hexagonal cells, the corner portion between two partition walls at least one of which is the partition wall separating inflow cells or outflow cells from each other is a specific corner portion, and the corner portion between the two partition walls each of which is the partition wall separating the inflow cell and the outflow cell is an unspecific corner portion. At least one of the specific corner portions is provided with a reinforcing portion so that a shape of the specific corner portion is rounded, and the unspecific corner portions are not provided with the reinforcing portions.
US09289709B2 Device to remove particles from a gas stream
A device to separate particles from a gas stream. The device may be a vacuum cleaner (10) or an industrial dust extraction device. The vacuum cleaner (10) includes a rotor assembly (20) to which the gas stream is delivered, the rotor assembly (20) having a plurality of gates (42) that collect dust and open to deliver dust to an outlet chamber (23). The gates (42) include one or more gates (42) that may include a resilient deflectable flange that is movable between an open and a closed position to provide for passage of the dust to the chamber (23).
US09289708B2 Tube separator as a separator of very fine particles for reducing fine dust emissions and avoiding stack rain
A separation system for separating drops from a flue gas flow for installation in a gas scrubber of a power plant or an incineration plant includes a front coarse separator arranged in a gas flow direction, and a rear final separator arranged in the gas flow direction. The rear final separator is provided to have a lower separation performance in comparison with an upstream separator in the gas flow direction and/or is provided as a tube separator.
US09289707B2 Porous material, manufacturing method of the same, and honeycomb structure
There are disclosed a porous material having excellent heat resisting properties and an excellent resistance to heat shock. A porous material contains aggregates and an amorphous binding agent to bind the aggregates to one another in a state where pores are formed among the aggregates, the binding agent contains a rare earth element, the amorphous binding agent preferably contains magnesium, aluminum, silicon, the rare earth element and oxygen, and the amorphous binding agent preferably contains 8.0 to 15.0 mass % of MgO, 30.0 to 60.0 mass % of Al2O3, 30.0 to 55.0 mass % of SiO2, and 1.5 to 10.0 mass % of the rare earth oxide.
US09289691B2 Interactive video game with visual lighting effects
A video game includes a peripheral device that senses the presence and identity of toy objects near or on the peripheral. Each of the toy objects includes an identification device such as an RFID tag. Each of the toys is also associated with a corresponding game character or object. The peripheral device provides lighting effects based on characteristics of the game character or aspects of the game play sequence thereby enhancing the user's gameplay experience.
US09289684B2 Method for implementing a computer game
A method, implemented as computer code being executed by one or more processors, in which a computing device displays computer game graphics showing a gameboard with multiple game elements that disappear when matched or switched, such as in a match-3, clicker or switcher game; and in which one or more of the processors are programmed such that: the gameboard includes an entry point and one or more exit points and the player completes a level of the game if he or she clears elements to make a path from the entry point to an exit point; and the game includes a virtual path though which the player progresses if he or she completes a level of the game; and that virtual path can, at some nodes, fork in several different directions and the position of the exit successfully reached in the gameboard determines which fork the player will take through the virtual path if the player completes a level.
US09289680B2 Game controller, storage medium storing game program, and game apparatus
A game controller includes at least four load sensors for detecting a load applied on a support board on which player's legs are ridden, and the game controller transmits a load value detected as manipulation data by the four load sensors to a game machine. The game machine determines a necessary quantity of load values, and the game machine computes the necessary quantity of load values based on the detected load value from the game controller. Then, game processing is performed based on the necessary quantity of computed load values.
US09289677B2 Modular dealing shoe for casino table card games
A playing card delivery shoe used in the play of the casino table card game of blackjack. The shoe may comprise: an area for receiving a first set of playing cards useful in the play of the casino table card game of blackjack; a first card mover that moves playing cards from the first set of playing cards to a playing card staging area wherein at least one playing card is staged in an order by which playing cards are removed from the first set of playing cards and moved to the playing card staging area; a second playing card mover that moves playing cards from the playing card staging area to a delivery area wherein playing cards removed from the staging area to the delivery shoe are moved in the same order by which playing cards were removed from the first set of playing cards and moved to the playing card staging area; and playing card-reading sensors that read at least one playing card value of each playing card separately after each playing card has been removed from the area for receiving the first set of playing cards and before removal from the playing card delivery area. There is a communication link between the playing card-reading sensors and a processor, and the processor analyzes the data and displays certain game-related data on a display device.
US09289671B2 Golf swing instruction device and method of use thereof
A golf swing instruction device is provided that includes first and second members, each being moveable with respect to one another by way of coupling arms coupled there between. Positioning members, for a golfer's feet and the golf ball, may be moved along a length of the first and second members to help position the golfer with respect to the ball. The first and second members may be positioned next to one another, may be moved away from each other on a first end or on an opposing second end, or may be moved away from one another on both ends such that first and second members are spaced apart from one another. In these configurations, the device assists the golfer in shaping a golf shot, such as a straight shot, fade, draw or putt.
US09289668B2 Skis and handlebar accessories for athletic training sleds
A training sled including a pair of nonlinear runners is disclosed arranged in parallel relative to a center axis and a plane. A head crossbar may extend between first ends of the runners and may be joined thereto so as to form a U-shaped member with the runners. A weight bearing member may be affixed to and extend between the pair of nonlinear runners near mid-sections thereof. A rear crossbar may extend between and may be disposed above the plane of the runners proximate second ends thereof and may be joined thereto opposite the head crossbar.
US09289662B2 Blade constructs and methods of forming blade constructs
A dual-core blade and method for manufacturing a dual-core blade are disclosed. The blade is formed with a first core portion and a second core portion comprising an epoxy having a plurality of expanded microspheres. The method of forming the two foams generally comprises sizing a foam core to form a first core portion and providing and preparing an epoxy mixture to form a second core portion. The first core portion and the second core portion of the epoxy mixture are placed into a preform, and the preform is heated slightly so as to cause the epoxy mixture to flow into the shape of the preform and around the first core portion. The first core portion and the second core portion are then bonded in a molding operation. The formed structure can form part of a hockey stick blade.
US09289657B1 Football with free moving weight
A football with a free moving weight. Implementations may include an outer cover, a bladder within the outer cover, and a free weight within the bladder.
US09289654B2 Golf ball with single layer core having specific regions of varying hardness
A golf ball comprising a single layer core formed from a substantially homogenous formulation and comprising a geometric center and an outer surface; a hardness of the outer surface is greater than a hardness of the geometric center. An inner core region is disposed about the geometric center and has a first hardness that is less than those of the geometric center and the outer surface; an outer core region is adjacent the outer surface and has a second hardness that is greater than those of the geometric center and the outer surface; and an intermediate core region is disposed between the inner and outer core regions and extends radially from about 5 mm to about 15.75 mm from the geometric center and has at least a third hardness and a fourth hardness, each of which are related to the first hardness and the second hardness in various ways.
US09289650B2 Multi-purpose ice axe including rotating spike
Generally, a spike including a rotary position selector which allows selectable incremental fixed angular positioning of the spike, the spike adaptable to couple to a tool. Specifically, an ice axe having a rotatable spike which allows selectable fixed angular positioning of the spike in relation to the shaft of the ice axe.
US09289648B2 Treadmill with deck vibration
A treadmill includes a support structure and a treadbase connected thereto. The treadbase has first and second opposing side rails extending along at least a portion of first and second sides of the treadbase, respectively. A deck is connected to and between the first and second opposing side rails. Front and rear pulleys are connected to and between the first and second opposing side rails. A continuous belt is trained around and rotatable about the front and rear pulleys. One or more vibration assemblies are connected to the deck and selectively create vibrations to cause the deck to vibrate. The vibrations are transferred to a user during the performance of exercise to provide various physiological benefits to the user.
US09289644B2 gym
The exercise apparatus of the present invention includes a supporting frame of limited height to which the pulley-carrying system is rotationally connected. The pulley frame is releasably movable by the operator utilizing a swivel locking mechanism. By this locking mechanism, the operator releases a handle to cause the frame to rotate 360 degrees. The pulley frame contains multiple pulley units engaged with multiple bands. A handle mechanism allows the operator to selectively choose from the various bands which allows various levels of resistance and various exercises.
US09289640B2 Resistance brace
A resistance brace includes a pair of hinged arms having plates cooperating with one another to define a first and second pivots point separated from one another by a distance. A pair of splints having limb-attachment portions and geared ends engaged with one another and pivotably coupled with the plates at the pivot points. An adjustable compression member is coupled with the plates to compress the plates against the geared ends so as to frictionally impede movement of the splints relative to the plates. A joint harness is coupled with the hinged arms to attach the resistance brace to a joint of a body so that the hinged arms are positioned on opposing sides of the joint relative to a plane of rotation of the joint. Attachment members are coupled with the splints to attach the resistance brace to a first and second body portions extending from the joint.
US09289634B2 Safety apparatus on a rope with indicator for indicating the state of closing of the flange-plates
A safety apparatus on a rope, including a first flange-plate, an operable second flange-plate, and a mechanical indicator collaborating when the swiveling movement takes place with both the first pivot-pin and a latch to indicate that the second flange-plate is in the closed and latched position, or in an unlatched ready-to-open state.
US09289632B2 Electrically charged filter and mask
Provided is an electrically charged filter which has a high initial filtering efficiency and is not liable to decline in filtering efficiency, by including a liquid-charged nonwoven fabric layer that is charged by application of force via a polar liquid, and a tribo-electrically charged nonwoven fabric layer that is charged by friction between fiber components of a plurality of types.
US09289629B2 Ultrasonic probe and manufacturing method of ultrasonic probe
An ultrasonic probe transmits vibration along longitudinal axis from the proximal toward the distal end, including: first area including proximal and distal end portions, a center axis parallel to the longitudinal axis, the first area having a vibration antinode position at the distal end, wherein maximum distance from the center axis to an outer peripheral surface in radial direction orthogonal to the center axis is a first distance; a treatment section located on a distal end side's barycenter position displaced from the center axis; a second area located between the first area and treatment section continuous with the distal end of the first area and gravity center axis parallel to the center axis to pass through the barycenter, wherein maximum distance from the center axis to the outer surface in the radial direction orthogonal to the center axis is a second distance equal to or shorter than the first distance.
US09289625B2 Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue
A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method.
US09289623B2 Method and device for monitoring and treatment of seasonal affective disorder
This invention provides for an energized biomedical ophthalmic device and associated method of measuring changes in biomarkers contained in tear film to generate data related to a light therapy regimen used to treat symptoms associated with seasonal affective disorder. In some embodiments, the energized biomedical ophthalmic device can include an energized contact lens with a light source in communication with a processor controlling said light source according to the light therapy regimen. The light therapy regimen may be generated or modified by the processor from the measured changes and sometimes from user's preferences, and/or additional measurements, including for example, light exposure and/or circadian rhythm of the user.
US09289622B2 Therapeutic light control system
A system for influencing a state of a user includes a display with a light source for emitting light influencing the state of the user. A light controller selectively controls the emission of the light including at least one of; (1) the spectrum of the light; (2) the duration of the light; 3) the distribution of the light; (4) the intensity of the light; and (5) the timing of the light. An analysis engine capable of providing a signal to the light controller indicating a desired emission of the light based upon selectively illuminating one or more of a plurality of different blue light sources, each of which having a different peak spectrum.
US09289620B2 Method and device for three-stage atrial cardioversion therapy
Methods and apparatus for a three-stage atrial cardioversion therapy that treats atrial arrhythmias within pain tolerance thresholds of a patient. An implantable therapy generator adapted to generate and selectively deliver a three-stage atrial cardioversion therapy and at least two leads, each having at least one electrode adapted to be positioned proximate the atrium of the patient. The device is programmed for delivering a three-stage atrial cardioversion therapy via both a far-field configuration and a near-field configuration of the electrodes upon detection of an atrial arrhythmia. The three-stage atrial cardioversion therapy includes a first stage for unpinning of one or more singularities associated with an atrial arrhythmia, a second stage for anti-repinning of the one or more singularities, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities delivered via the near-field configuration of the electrodes.
US09289613B2 Interdevice impedance
An electrical parameter value indicative of an impedance of an electrical path between a first medical device implanted within a patient and a second medical device implanted within the patient may be determined by generating and delivering an electrical signal between electrodes connected to the first medical device and sensing the electrical signal with two or more sense electrodes connected to the second medical device. In some examples, the electrical parameter value indicative of the impedance may be used to detect a system integrity issue, such as relative movement between the first and second medical devices, such as between leads connected to the medical devices, or a lead-related condition. In other examples, the determined impedance may indicate a transthoracic impedance of the patient.
US09289612B1 Coordination of ventricular pacing in a leadless pacing system
An implantable medical system is configured to coordinate ventricular pacing with intrinsic depolarizations of another chamber. The implantable medical system includes a leadless pacing device implanted on or within the ventricle. Another implantable medical device is configured to sense an intrinsic depolarization the other chamber of the heart of the patient, and in response to the intrinsic depolarization of the other chamber, deliver an electrical pulse. The leadless pacing device is configured to detect the electrical pulse delivered by the other implantable medical device and, in response to detecting the electrical pulse delivered by the other implantable medical device, deliver a pacing pulse to the ventricle via at least a first electrode in coordination with the intrinsic depolarization of the other chamber.
US09289610B2 Fractionalized stimulation pulses in an implantable stimulator device
A method for configuring stimulation pulses in an implantable stimulator device having a plurality of electrodes is disclosed, which method is particularly useful in adjusting the electrodes by current steering during initialization of the device. In one aspect, a set of ideal pulses for patient therapy is determined, in which at least two of the ideal pulses are of the same polarity and are intended to be simultaneous applied to corresponding electrodes on the implantable stimulator device during an initial duration. These pulses are reconstructed into fractionalized pulses, each comprised of pulse portions. The fractionalized pulses are applied to the corresponding electrodes on the device during a final duration, but the pulse portions of the fractionalized pulses are not simultaneously applied during the final duration.
US09289609B2 Neurostimulation system for selectively estimating volume of activation and providing therapy
An external control device, neurostimulation system, and method of programming a neurostimulator. A volume of tissue activation for each of a first one or more candidate stimulation parameter sets is simulated without conveying electrical stimulation energy into the tissue. One of the first candidate stimulation parameter set(s) is selected based on each simulated volume of tissue activation. Electrical stimulation energy is conveyed into the tissue in accordance with a second one or more candidate stimulation parameter sets, wherein the initial one of the second candidate stimulation parameter set(s) is the selected one of the first candidate stimulation parameter set(s). One of the second candidate stimulation parameter set(s) is selected based on a therapeutic efficacy of the electrical stimulation energy conveyed into the tissue. The neurostimulator is programmed with the selected one of the second candidate stimulation parameter set(s).
US09289608B2 Device and circuitry for controlling delivery of stimulation signals
Embodiments relate to a device for controlling delivery of stimulation signals, comprising: a stimulation delivery circuit; a monitoring component to monitor voltage supplied in at least one current-driven charge pulse via the stimulation delivery circuit; and a stimulation control component to control voltage supplied in at least one subsequent charge pulse based on the charge of the at least one charge pulse delivered by the stimulation delivery circuit. The device may further comprise a model generation component to generate an impedance model of stimulation electrodes in the stimulation delivery circuit, wherein the stimulation control component is configured to control the stimulation delivery circuit to deliver charge according to the impedance model.
US09289601B2 Systems and methods for making and using a tool for steering a paddle lead of an electrical stimulation system
A paddle lead insertion kit includes a paddle lead and an insertion kit. The paddle lead includes a stylet lumen defined in a paddle body. The insertion tool includes a stylet channel defined along the insertion tool. A stylet is disposed in the stylet channel and transitions between a refracted position and an extended position. When the stylet is in the retracted position, the stylet is disposed completely within the stylet channel. When the stylet is in the extended position, the stylet extends outwardly from the stylet channel and is insertable into the stylet lumen of the paddle lead. A slide assembly is coupled to the stylet and controls transitioning of the stylet between the retracted position and the extended position.
US09289600B2 Electrical stimulation paddle leads and methods of making and using
An electrical stimulation lead includes a paddle body, at least one lead body having a distal end, a proximal end, and a longitudinal length with the distal end of the lead body coupled to the paddle body. The lead further includes fixation elements and electrodes. The fixation elements are disposed entirely within the paddle body and the electrodes are disposed on the paddle body. Each of the electrodes includes a stimulating element with an exposed stimulation surface, and a piercing element extending from the stimulating element into the paddle body and making contact with at least one of the fixation elements. Further, the lead includes terminals disposed along the proximal end of the lead body and conductor wires electrically coupling the electrodes to the terminals. In addition, methods of making stimulation leads using sacrificial portions of electrodes are presented.
US09289597B2 Guide catheter having vasomodulating electrodes
A guide catheter system includes a guide catheter having a proximal end, a distal end, an outer wall and a first, second and third electrode wherein the first, second and third electrodes are spaced longitudinally apart from each other on the outer wall of the catheter, and an electrical impulse generator connected to the guide catheter wherein the electrical impulse generator includes a circuit for selecting an adjacent pair of electrodes to use as a bipolar electrode system to send an electrical impulse and a method of use thereof to treat vasospasm.
US09289592B2 Systems, apparatuses, and methods for differentiating between multiple leads implanted within a patient
Systems, apparatuses, and methods for differentiating between multiple leads that are implanted within a patient include a stimulator configured to be implanted at an implant site within the patient and generate electrical stimulation current, a plurality of leads each comprising one or more electrodes configured to deliver the electrical stimulation current at a stimulation site within the patient, and a shuttle assembly having a plurality of receiving ports each configured to receive a proximal portion of one of the leads and guide the leads from the stimulation site to the implant site of the stimulator. The shuttle assembly is configured to enable a user to differentiate between each of the leads after the leads are guided to the implant site of the stimulator.
US09289590B2 Peelable lid for container with multi-point peel system
A peelable lid system includes a peelable lid, a seal configured to seal the peelable lid to a container, a handle coupled to the peelable lid, and a lifting mechanism coupled to handle. The lifting mechanism can be coupled to the peelable lid at a plurality of attachment points, including at least one attachment point coupled to the peelable lid away from the handle. The lifting mechanism can be configured to lift at least one portion of the peelable lid near each of the plurality of attachment points.
US09289584B2 Remotely controlled drug delivery systems
Drug delivery devices responsive to at least one external stimulus are described, along with methods for their preparation and use. The devices can be configured to respond to the stimulus, providing “on demand” release of one or more deliverables such as pharmaceutical drugs.
US09289583B2 Methods for administering small volume oral transmucosal dosage forms using a dispensing device
Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.
US09289578B2 Reducing incremental measurement sensor error
For position sensors, e.g., a fiber-based system, that build a shape of an elongated member, such as a catheter, using a sequence of small orientation measurements, a small error in orientation at the proximal end of the sensor will cause large error in position at distal points on the fiber. Exemplary methods and systems are disclosed, which may provide full or partial registration along the length of the sensor to reduce the influence of the measurement error. Additional examples are directed to applying selective filtering at a proximal end of the elongated member to provide a more stable base for distal measurements and thereby reducing the influence of measurement errors.
US09289575B2 Catheter
A catheter has an entrance opening defined by the first end of a catheter body and non-smooth inner surface. The entrance opening intersects a longitudinal axis extending longitudinally through the center of a lumen adapted to drain urine from a bladder. The non-smooth inner surface can have dimples, channels, or grooves, all of which decrease frictional fluid forces against the inner surface as the urine drains. The catheter is free of any eyelets formed in the side wall of the catheter body. The catheter is further free from any hemispheric tip located at one end.
US09289574B2 Three-channel tuned LED lamp for producing biologically-adjusted light
An LED lamp comprising a housing, a drive circuit, and a plurality of LED dies driven by the drive circuit, The plurality of LED dies may be in a ratio of at least one of 15 mint LED dies to 5 hyper red LED dies to 4 blue LED dies and 1 mint LED die to 1 hyper red LED die to 1 blue LED die. The drive circuit may operate the LED dies such that a relative peak intensity of the blue LED dies is within the range from 80%-90% or 90%-100% of a peak intensity of the hyper red LED dies, and a relative peak intensity of the mint LED dies is within the range of 50%-60% or 30%-40% of the peak intensity of the hyper red LED dies.
US09289573B2 Ventilator pressure oscillation filter
A ventilation air pressure oscillation mitigation device for a ventilator includes a housing defining an inlet and an outlet. The device includes a valve seat defining a primary opening and a plurality of secondary openings. A valve body is selectively positionable in a first position and a second position within the device. In the first position, substantially all of a first flow of ventilation air from the inlet to the outlet passes through the primary opening. When the valve body is in the second position, all of a second flow of ventilation air from the inlet to the outlet passes through the plurality of secondary openings. An actuator controls a position of the valve body.
US09289571B2 Breathing assistance apparatus
Breathing assistance apparatus includes a gases supply unit adapted to, in use, deliver a stream of pressurised gases from an outlet. The gases supply unit is adapted to vary the pressure of the stream of pressurised gases. A supply path includes a flexible self-supporting gases transportation pathway having a first end connected to the outlet so that the gases transportation pathway receives the stream of gases and conveys the gases to a patient. A patient interface is connected to the second end of the gases transportation pathway receives a stream of gases. At least one sensor measures at least one information parameter of the supply path. A control system associated with the gases supply unit receives the information parameter. The control system contains reference data, and compares the received data to reference data, and determines a supply path based on the comparison.
US09289562B2 Pressure actuated valve for multi-chamber syringe applications
Methods and apparatus are disclosed for disposing a valve within a barrel of a conventional syringe to provide, first, a mixing syringe embodiment and, second, a sequential delivery syringe embodiment. Generally, the valve divides the syringe barrel into a proximal and a distal chamber. When used for mixing, the valve is self-displaceable by expansion of decompressing matter disposed within the valve against exterior matter permitting proximal displacement of the valve independent of character of matter in the distal chamber. For sequential delivery, switching of the valve occurs after switch opening causing pressure is relieved, thereby reducing inadvertent uncontrolled flow when the valve opens. In addition, a combination mixing and flush syringe is disclosed whereby a mixing and a flush capability is provided within a conventional syringe.
US09289561B2 Reversely rotatable dose setting mechanism for an injection device
A dosing mechanism for use with an injection device to adjust a dose to be discharged from the injection device, the dosing mechanism including an adjusting element which can be moved relative to the dosing mechanism and including a coupling element for being releaseably coupled to a threaded bar associated with the injection device such that the adjusting element can be moved relative to the bar in one direction while a relative movement in the opposite direction is prevented, the dosing mechanism further including a retaining element with an engaging element for preventing the bar from being rotated in at least one direction, and a releasing element for uncoupling the adjusting element and bar.
US09289557B2 Plastic stopper
A stopper adapted for attachment with a plunger rod for use within a syringe barrel includes a main body portion defining an open rearward end configured to receive the plunger rod. The main body portion is manufactured from a rigid or semi-rigid polymeric material having an elastic modulus in the range of about 0.01 GPa to about 5 GPa. When fluid pressure is increased inside the syringe barrel during an injection, at least one of the following actions occurs: a) a flexible roof of the main body portion expands in a radial direction toward an inner wall of the syringe barrel; b) a first perimetrical skirt extending around an outer circumference of the main body portion is forced against an inner wall of the syringe barrel; and c) an engagement between the plunger rod and an engagement portion provided along an inner circumference of the main body portion.
US09289556B2 Syringe with plunger rod having a flexible portion
A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed.
US09289552B2 Infusion pump with drive device and blocking mechanism for the infusion syringe piston drive head
A drive device of an infusion syringe piston drive head for moving an infusion syringe piston is described. The device includes an advancing means including an advancing slide, an advancing spindle and a multi-part advancing spindle nut having at least one radially movable nut shell, and a blocking means adapted to be automatically triggered by a control sensor for blocking an infeed motion of the drive head in which the advancing slide is drivable by the advancing spindle nut at the advancing spindle and in which the drive head is arranged at the advancing slide, wherein the blocking means adapted to be automatically triggered by a control sensor includes the multi-part advancing spindle nut for blocking the infeed motion of the drive head on the advancing spindle.
US09289550B1 Apparatus and method for detecting fluid extravasation
An apparatus for the detection of extravasation of an injection fluid infused into a tissue during an imaging procedure is disclosed. The apparatus includes at least a first source of energy to supply an X-ray or gamma ray imaging energy to tissue in the vicinity of a site and at least a first sensor to measure an energy signal resulting from the energy supplied to the tissue by the first imaging energy source, and circuitry configured to compare the energy signal detected by the first sensor to a baseline measurement and provide an alert that extravasation is occurring.
US09289545B2 Controlling an apparatus for fluid transfer to and/or from a subject
A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20). The control system (23) is configured to, in the pre-treatment mode, process the measurement data for identification of a characteristic change indicating a connection of the blood circuit (20) to the vascular system of the patient, and, upon such identification, take dedicated action. The action may involve activating at least part of a patient protection system and/or enabling entry into the blood treatment mode. The control system may be included in an apparatus (200) for blood treatment, such as a dialysis machine.
US09289535B2 Polymers of fluorinated monomers and hydrocarbon monomers
It is a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.
US09289533B2 Collagen scaffold modified by covalent grafting of adhesion molecules, associated methods and use thereof for cardiovascular and thoracic cell therapy and contractile tissue engineering
Materials and methods for improving the biological properties and electromechanical performance of collagen scaffolds used for cell transplantation, including the fixation of biocompatible reagents and adhesion molecules which control cell adhesion, apoptosis, survival and/or differentiation simultaneously. The grafting of adhesion molecules to collagen matrices renders same suitable for use in vascular and cardiothoracic surgery/medicine, as well as in cell therapy for the heart and in artificial heart muscle engineering. Also, a simple method for grafting and optimising the presentation of adhesion peptides or biological agents when the scaffold is made from collagen and/or contains accessible thiol, amine or carboxyl groups.
US09289528B2 Methods for using indicator compositions
An indicator composition can be exposed to various environmental conditions stimuli such as in sterilization or storage processes. This indicator composition has a) a first polymeric particle comprising a solid continuous polymeric phase and a first reactant, the first polymeric particle having a mode particle size equal to or less than 50 μm; and b) a second reactant outside of the first polymeric particle, which second reactant is capable of reacting with the first reactant when exposed to a chosen environmental condition stimulus. The indicator composition can be used by exposing it to the environmental condition stimulus for a sufficient time to cause a detectable change in the indicator composition such as a detectable color change.
US09289527B1 UV disinfection system with ballast current monitoring
An ultraviolet radiation system to decontaminate small objects such as TV remote controls, hospital bed controls, cell phones, computer tablets and the like which are present in a hospital or other health care facility. The system includes a plurality of UVC lamps arranged in a table top sized housing and having a UVC transmissive shelf in the housing for support of objects to be decontaminated. The system has a microprocessor based controller and can kill Clostridium difficile and other pathogens to thereby decontaminate items in 30 seconds or less.
US09289526B2 Ultrasonic decontamination device
[Problem to be Solved] A device and a method for efficiently decontaminating a device used to culture cells are provided.[Means for Solving Problem] A decontamination device for decontaminating a device used to culture cells, manipulate microorganisms, or perform a sterility test, the device comprising an ultrasonic atomizer that atomizes a peracetic acid disinfectant by using ultrasonic oscillation to discharge droplets, a diffusion fan, a temperature-humidity sensor, and a controller.
US09289522B2 Systems and containers for sterilizing a fluid
A system for sterilizing a fluid includes a fluid source and a sterilization container bounding a fluid flow path that is in fluid communication with the fluid source. The sterilization container is comprised of one or more polymeric walls. An electron beam generator is configured to direct an electron beam through at least a portion of the fluid flow path of the sterilization container, the electron beam being sufficient to sterilize a fluid within the fluid flow path.
US09289521B2 Container sterilization apparatus and method
Provided is an apparatus for sterilizing containers with a conveying device, which conveys the containers along a pre-set conveying path. A first sterilization device acts upon at least one area of the containers with radiation in order to sterilize them. A checking device is arranged downstream with respect to the first sterilization device along the conveying path in order to check the sterilization procedure. The checking device is used for analyzing at least one medium occurring in the region of the containers.
US09289519B2 Alpha emitting constructs and uses thereof
The present invention discloses methods for treating non-malignant cell diseases by administering to an individual a construct comprising actinium-225 or bismuth-213 and an antigen of a non-malignant cell. Also, provided is a method for treating a solid tumor associated with an abnormal proliferation of cells by targeting an antigen of the tumor-associated vasculature with the constructs.
US09289517B2 Fluorescent emulsion of indocyanine green
The present invention relates to a formulation of indocyanine green in the form of a nanoemulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily phase comprises indocyanine green, at least one amphiphilic lipid and at least one solubilizing lipid.It relates also to a process for the preparation and to the use of the formulation.
US09289510B2 Polymeric drug delivery conjugates and methods of making and using thereof
Described herein are biodegradable drug delivery conjugates for effectively delivering bioactive agents to a subject. The drug delivery conjugates comprise a water-soluble high molecular weight linear biodegradable polymer backbone comprising a plurality of linear water-soluble polymeric segments connected to one another by a first (main-chain) cleavable linker, wherein a bioactive agent is covalently bonded to at least one water-soluble polymeric segment, at least one cleavable linker, or a combination thereof. The conjugates possess numerous advantages over prior art delivery conjugates. Also described herein are methods for making and using the conjugates.
US09289506B2 Surface binding of nanoparticle based drug delivery to tissue
Microparticles and nanoparticles and compositions thereof are provided. The microparticles and nanoparticles and compositions may be used for the treatment of musculoskeletal disease, such as osteoarthritis and injury.
US09289504B2 Single protein nanocapsules for protein delivery with long-term effect
A protein nanocapsule having a single-protein core and a thin polymer shell anchored covalently to the protein core.
US09289499B2 Continuous flow production of gelatin nanoparticles
A continuous process for the preparation of gelatin based nanoparticles in a reactor having a process channel having a mixing element therein, the process having the following steps: A) feeding separately an aqueous gelatin solution at a first rate and a water-miscible organic solvent at a second rate to the process channel of the reactor to be mixed therein, to form a suspension of non-crosslinked gelatin based nanoparticles and B) crosslinking the non-crosslinked gelatin based nanoparticles, wherein the sum of the first rate and the second rate is chosen such that the reactor has a mixing efficiency as determined by the Villermaux/Dushman method of between 0.1 and 1.5 and the period from the time point at which the aqueous gelatin solution is fed to the reactor to the time point at which the mixture of the aqueous gelatin solution and the organic solvent contacts the mixing element is at most 15 seconds.
US09289495B2 Systems and methods for treatment of allergies and other indications
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of a hostile biophysical environment. One set of embodiments provides a composition for topical delivery comprising an H1 antihistamine and/or a salt thereof, and optionally, a hostile biophysical environment and/or a nitric oxide donor. In some cases, the composition may be stabilized using a combination of a stabilization polymer (such as xanthan gum, KELTROL® BT and/or KELTROL® RD), propylene glycol, and a polysorbate surfactant such as Polysorbate 20, which combination unexpectedly provides temperature stability to the composition, e.g., at elevated temperatures such as at least 40° C. (at least about 104° F.), as compared to compositions lacking one or more of these.
US09289492B2 Collecting ovarian cancer stem cells from ovarian cancer cells
The present invention relates to compositions and methods for treating, characterizing and diagnosing ovarian cancer. In particular, the present invention provides methods for treating and/or preventing ovarian cancer in a subject by administering to the subject an effective amount of Mullerian Inhibiting substance and/or an effective amount of an agent that inhibits BCRP1. The present invention further provides methods to identify and/or enrich for populations of ovarian cancer stem cells and populations of somatic ovarian stem cells, in particular, enrichment for populations of coelomic somatic ovarian stem cells, subcoelomic/stromal somatic ovarian stem cells and periphilar medullary somatic ovarian stem cells. The present invention also provides somatic ovarian stem cell markers and ovarian cancer stem cell markers, as well as methods to identify agents which selectively inhibit the proliferation of ovarian cancer stem cells as compared to somatic ovarian stem cells.
US09289491B2 Method and composition for hyperthermally treating cells
A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells.
US09289486B2 Attenuated fhaC mutants of Pasteurellaceae bacteria and vaccine compositions thereof
Gram negative bacterial virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of novel gram negative bacterial mutants useful in vaccines.
US09289484B2 Attenuated Streptococcus suis vaccines and methods of making and use thereof
The present invention provides attenuated S. suis strains that elicit an immune response in animals against S. suis, compositions comprising said strains, methods of vaccination against S. suis, and kits for use with such methods and compositions. The invention further provides novel, mutagenically-induced mutations in S. suis genes, which are useful in the production of novel attenuated S. suis bacterial strains.
US09289481B2 Incapacitated whole-cell immunogenic bacterial compositions produced by recombinant expression
The present invention features incapacitated whole-cell bacterial immunogenic compositions and methods of their production, which compositions are useful to deliver antigens in a manner resembling the live infectious organism in terms of elicitation of a robust immune response, but with reduced risk or no risk of disease. The compositions of the invention are produced by rendering a bacterium bacteriostatic through expression of a recombinant promoter in the bacterial cell, which promoter can be operably linked to a polynucleotide encoding a recombinant gene product. In one embodiment, where the bacterium is a gram negative host, the recombinant gene product provides for reduced toxicity of LPS. In one embodiment, the gene product is a bacteriophage protein, such as endolysin, holin, or ndd.
US09289478B2 Formulations of tumour-associated peptides binding to human leukocyte antigen (HLA) class I or class II molecules for vaccine
The present invention relates to novel formulations of tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules as vaccines for the use in immunotherapeutic methods. In particular, the present invention relates to formulations for the immunotherapy of cancer, in particular renal and brain cancer, in particular glioma, especially glioblastoma cancer. The present invention furthermore relates to vaccine compositions for eliciting anti-tumor immune responses.
US09289477B2 Tolerogenic synthetic nanocarriers to reduce cytotoxic T lymphocyte responses
Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class II-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes.
US09289474B2 Agent for use in the case of fructose intolerance
There is provided in accordance with embodiments of the invention a method of treating or reducing the effects in a subject of a condition selected from fructose intolerance and impaired fructose metabolism, the method comprising administering to a subject in need of such treatment or reduction an efficacious amount of a glucose isomerase, other than in combination with 5-D-fructose dehydrogenase. Other embodiments are also disclosed.
US09289472B2 Use of HSP70 as a regulator of enzymatic activity
The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the step of administering or inducing Hsp70, or a functional fragment or variant thereof, in a form suitable for allowing interaction between BMP and Hsp70, or said functional fragment or variant thereof, and thereby modulating the enzymatic activity of an enzyme interacting with BMP.
US09289470B2 Combination of an anti-EDb fibronectin antibody-IL-2 fusion protein, and a molecule binding to B cells, B cell progenitors and/or their cancerous counterpart
The present invention relates to a combination of an anti-EDb fibronectin antibody-IL-2 fusion protein, and a molecule binding to B cells, B cell progenitors and/or their cancerous counterpart and uses thereof.
US09289467B2 Compositions and methods for treating bone conditions
A method of treating a degenerative bone condition of a subject includes administering to hematopoietic progenitor cells or osteoclast progenitor cells of the subject at least one agent that substantially reduces the interaction of at least one of C3a or C5a with the C3a receptor (C3aR) and/or C5a receptor (C5aR), a STAT3/IL-6 signaling pathway antagonist, and a combination thereof, the agent being administered to the hematopoietic progenitor cells or osteoclast progenitor cells at an amount effective to inhibit osteoclast differentiation of hematopoietic progenitor cells or osteoclast progenitor cells.
US09289466B2 Modified binding proteins inhibiting the VEGF-A receptor interaction
The present invention relates to binding proteins specific for Vascular Endothelial Growth Factor A (VEGF-A), in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx (wherein xxx denotes the amino acid length of the VEGF-A mature protein) binding to Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2). Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.
US09289462B2 Method for medical treatment utilizing glutathione
A method of treating a condition or conditions caused by damage to cells by a process of oxidative stress and glutathione depletion. In some exemplary embodiments, the condition or conditions may be treated by administering reduced L-glutathione to a patient through injection or intravenous infusion. In other exemplary embodiments, the condition or conditions may be treated by administering reduced glutathione monoethyl ester through injection or intravenous infusion.
US09289461B2 Reducing the risk of autoimmune disease
The present disclosure provides a method for reducing the risk of autoimmune disease by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition, may reduce the symptoms of autoimmune disease and may be a treatment for autoimmune disease, especially type 1 diabetes. Preferably, the hydrolysate consists of peptides with a molecular weight of more than 500 Da.
US09289460B2 Use of natural active substances in cosmetic or therapeutic compositions
The invention relates to cosmetic or therapeutic compositions that contain hydrolyzed yeast proteins as an active ingredient, to the use of said cosmetic or therapeutic compositions, and to a method for cosmetic treatment.
US09289457B2 Composition for preventing or treating liver diseases, containing plant stem cell lines derived from the cambium of Panax ginseng including mountain ginseng or ginseng as active ingredient
The present invention relates to a composition for preventing or treating liver diseases, which contains, as an active ingredient, any one or more of a homogeneous cell line derived from the cambium of Panax ginseng, including wild ginseng or ginseng, a lysate thereof, an extract thereof and a culture medium thereof. The homogeneous cell line according to the present invention, a lysate thereof, an extract thereof and a culture medium thereof have minimized side effects compared to existing agents for treating liver diseases, and thus are safe for the human body. Also, they can increase the levels of s-antibody (HBsAb) and e-antibody (HBeAb) against hepatitis virus and inhibit the proliferation of hepatitis virus, and thus they are useful for the prevention and treatment of liver diseases. In addition, they have the effect of lowering the levels of liver injury, and thus are useful as a functional food for improving liver function.
US09289454B2 Method for manufacturing multilayered cell sheet, multilayered cell sheet having vascular network obtained thereby, and method of use thereof
A method for producing multilayered cell sheets, including producing a vascular bed which includes an artery-vein loop and in which a capillary vascular network is constructed; layering cell sheets on the vascular bed; and perfusing a culture medium in vitro to construct a vascular network in the cell sheets. The production method enables vascular networks to be constructed in cell sheets and enables thick multilayered cell sheets to foe easily produced by layering the cell sheets. Such thick multilayered cell sheets are useful as in vivo tissue-like products for regenerative medicine for various tissues and for evaluation of drugs and the like.
US09289450B2 Silver-containing antimicrobial articles and methods of manufacture
A silver composition comprising silver sulfate, methods of making antimicrobial articles, particularly packaged antimicrobial articles, methods of whitening antimicrobial articles, and packaged antimicrobial articles.
US09289444B2 Composition for promoting hematogenesis containing quercetin 3-O-β-(2″-galloyl)-rhamnopyranoside as active ingredient
This invention relates to a composition for promoting hematopoiesis and for treating, preventing or alleviating cytopenia or bone marrow failure comprising quercetin 3-O-β-(2″-galloyl)-rhamnopyranoside (QGR) as active ingredient. The present active compound QGR (i) increases dose dependently the mRNA expression of cytokines involved in hematopoiesis including stem cell factor, granulocyte-macrophage colony stimulating factor and erythropoietin from mouse bone marrow mononuclear cells, (ii) promotes the formation of burst forming unit-erythroid and colony forming unit-fibroblast, (iii) stimulates the generation of cells positive for TER-119, a specific marker of mouse erythroid precursors, (iv) promotes erythropoiesis, leukopoiesis, thrombopoiesis, and hemoglobin production in bone marrow failure mouse model, (v) stimulates the formation of hematopoietic stem/progenitor cells and mesenchymal stem/progenitor cells, (vi) stimulates megakaryocyte formation surrounding the blood system of damaged bone marrow, osteoid formation and bone marrow restoration through a recovery of damaged bone marrow microenvironment. The QGR of the present invention can be used for promoting hematopoiesis and treating cytopenia or bone marrow failure.
US09289441B2 Osteoclast inhibitors such as zoledronic acid for low back pain treatment
Methods for the safe administration of imidazole or imidazolium compounds, and conditions that may be treated by these methods, are described herein.
US09289439B2 Intravenous formulation with water-soluble cocrystals of acetylsalicylic acid and theanine
A method of reducing hepatocellular damage in a subject using a water-soluble cocrystal composition which contains a quantity of acetylsalicylic acid and a quantity of a theanine enantiomer.
US09289436B2 Method of treatment of prostate cancer with androgen receptor and glucocorticoid receptor antagonists
Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
US09289427B2 Polymorphic forms of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-hydrochloride salt and processes of manufacturing thereof
The present invention relates to 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer.
US09289421B2 Methods and compositions for reducing serum levels of immunoglobulin E (IgE)
The present disclosure provides methods and pharmaceutical compositions for reducing the serum level of immunoglobulin IgE in an animal or human subject. It has been found that reducing or inhibiting the activity of the cannabinoid receptor CB2 leads to an increase in IgE in serum levels. Conversely, activation of the CB2 receptor by an agonist results in a reduction in IgE serum levels. The compositions and methods of the disclosure, therefore, provide a means to reduce or eliminate symptoms of immune system-related conditions resulting from IgE generation, such as an allergy, hay fever, and the like.
US09289412B2 Role of limonoid compounds as neuroprotective agents
Disclosed herein are neuroprotective compounds. Methods for the preparation of such compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the compounds disclosed, alone or in combination with other therapeutic agents, for the treatment of neurodegenerative conditions are provided.
US09289395B2 Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
US09289394B2 Compositions for treatment of attention deficit hyperactivity disorder
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of active drug in a delayed and controlled release formulation. The dosage form can be administered at night and drug release is delayed for from 5 to 8 hours or longer, followed by a prolonged release.
US09289392B2 Extended release pharmaceutical composition of entacapone or salts thereof
There is provided an extended release pharmaceutical composition comprising from about 200 mg to about 1000 mg of entacapone or salts thereof, optionally with other pharmaceutically acceptable excipients. The invention also provides an extended release pharmaceutical composition comprising triple combination of from about 30 mg to about 300 mg of levodopa, 10 mg to about 100 mg of carbidopa and 200 mg to about 1000 mg of entacapone or salts thereof, optionally with other pharmaceutically acceptable excipients. The invention also relates to process of preparation of such compositions.
US09289386B2 Oral film-form base and oral film-form preparation
The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a drug. The base is produced by dispersing, in an organic solvent having a solubility parameter of 9.7 or higher, an edible polymer soluble in water and the organic solvent, and particles of one or two or more compounds selected from the group consisting of mono- to hexasaccharide sugars and sugar alcohols thereof which have an average particle size of 0.1 μm to 60 μm and are insoluble in an organic solvent. The present invention can therefore provide oral film-form base and preparation which have a rapid dissolution profile in the mouth and sufficient film strength, and provide a reduced sticky sensation attributed to the water-soluble polymer in the mouth and an improved feel when handled with the fingers.
US09289384B2 Osteoclast inhibitors for knee conditions
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions.
US09289382B2 Vaginal inserted estradiol pharmaceutical compositions and methods
According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
US09289380B2 Long acting parasiticidal composition containing a salicylanilide compound, a polymeric species and at least one other anti-parasitic compound
A composition prepared for treating animals suffering from parasites which parasites are known to be susceptible to at least one of the avermectins, milbemycins or salicylanilides, comprises for example ivermectin in an amount of from 0.1 to 10%(w/v), a solvent selected from the group consisting of glycerol formal, propylene glycol, polyethylene glycol and combinations thereof, and a salicylanilide such as closantel in a required dosage amount for the animal to be treated, typically about 2.5 mg/kg live weight of the animal to be treated, a polymeric species selected from the group consisting of polyvinylpyrrolidone and polyoxypropylene/polyoxyethylene block copolymers, the said polymeric species improving the bioavailability of closantel to the extend that blood plasma levels of the said compound greater than about 20 ppm over period of treatment are achievable.
US09289378B2 Antimicrobial amorphous compositions
The present invention comprises compositions and methods for providing antimicrobial compositions. The antimicrobial compositions comprise gel delivery vehicles comprising stabilized silver, wherein ionic silver is provided to a site for antimicrobial purposes. Methods of making and using such compositions are taught, including application of the silver-containing gel compositions to wounds, burns, abrasions, cuts, surgical incision, sites where skin or organ integrity has been breached, and other sites to supply an antimicrobial environment.
US09289372B2 Cosmetic
A cosmetic has a polymer (A) having a content of an oxyalkylene unit and/or a glycerin unit of 0.5% by mass or more and under 5.0% by mass; and a polymer (B) having a content of an oxyethylene unit and/or a glycerin unit of 5.0% by mass or more and 20.0% by mass or less, the polymer (A) and the polymer (B) being a crosslinking organopolysiloxane polymer obtained by reacting organohydrogen polysiloxane having two or more hydrogen atoms bonded to a silicon atom in one molecule and polyoxyalkylene and/or polyglycerin having two or more aliphatic unsaturated bonds in one molecule, wherein the mass ratio of the polymer (A) to the polymer (B) is 5:95 to 60:40.
US09289371B2 Emulsion and cosmetic composition
An emulsion is obtained from emulsion polymerization of a mixture of (a) 1-50 wt % of a triorganosiloxysilicic acid and (b) 50-99 wt % of an ethylenically unsaturated monomer in the presence of (c) an emulsion stabilizer which is an anionic surfactant, nonionic surfactant or polyvinyl alcohol. The emulsion is used to formulate a cosmetic composition capable of forming, on drying, a film which has water resistance, oil resistance and toughness and is thus effective for preventing makeup deterioration. The cosmetic composition containing the emulsion is useful as eyeliner, mascara, eyebrow color, liquid foundation or milky lotion.
US09289369B2 Non-aqueous oral care composition containing dental occlusion actives
A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt. % water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.
US09289366B2 Organoleptic compounds
The present invention relates to novel compounds and their use as fragrance materials.
US09289365B2 Compositions and methods for stimulating collagen synthesis in the skin
Cosmetic compositions comprising substituted carbamoyl heterocyclic analogs and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The substituted carbamoyl heterocyclic analogs are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.
US09289362B2 Foaming compositions and methods
An effervescent foamable two-component oral care composition in which a first component contains an acid, and a second component contains an alkaline source such as a carbonate; wherein one or both of the first and second components also contains a surfactant; and, wherein the first and second components are combinable to form an effervescing oral care foam.
US09289361B2 Compositions comprising an NFκB-inhibitor and a non-retinoid collagen promoter
The present invention relates to a composition comprising an NFκB-inhibitor and a non-retinoid collagen promoter.
US09289360B2 Dental composition
An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, and (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant side chains, (c) optionally dispersed nanoparticles, and (d) optionally a low molecular compound, characterized in that the glass ionomer composition comprises—S.sub.xH groups, wherein x is an integer of from 1 to 6, which crosslink the particulate glass and/or the linear polycarboxylic acid and/or the optional dispersed nanoparticles and/or the optional low molecular compound.
US09289357B2 Bottle teat
A bottle teat made of a soft elastic material, comprising: a hollow suction nipple, a circumferential mounting edge for fixation to the bottle opening of a drinking bottle, a hollow transition zone between the mounting edge and the suction nipple, and two drinking slots extending from the outer side to the inner side of the suction nipple in an end region of the suction nipple, which are aligned in parallel to each other and whose distance from each other decreases from the outer side towards the inner side of the suction nipple.
US09289353B2 Pedicure basin with overflow protection
A spa chair with a novel pedicure basin is disclosed. The pedicure basin has a main basin and a secondary basin. The main basin is where the feet of the person sitting in the spa chair goes. This main basin is generally filled with water. In one embodiment, the main basin has water overflow protection through a lowered rim, directing the overflow of water to a secondary basin. This method of overflow protection is especially useful where the main basin has a liner blocking the drain hole within the main basin.
US09289350B2 Air pulsator control system
A device and method coupled to a therapy garment to apply pressure and repetitive compression forces to a body of a person has an air pulsator and a user programmable time, frequency and pressure controller operable to regulate the duration of operation, frequency of the air pulses and a selected air pressure applied to the body of a person.
US09289349B2 Sound therapy systems and methods for recalibrating the body's electromagnetic field
A sound treatment system includes an audio system for transmitting tones of predetermined frequencies through a plurality of outputs. A sound transmitting device is electrically connectable to one or more of the outputs, and includes a speaker for transmitting the tones received. The speaker is adjacent to crystal which is vibrationally responsive to the tones. A method of using the system includes generating tonal segments of predetermined duration, modulating the frequencies, and compiling these into an audio program. One or more sound transmitting devices are placed on desired locations of the body, and their inputs connected to corresponding outputs of the audio system. The generating step includes compiling selected predetermined frequencies into an audio program to generate the tonal segments, as well as modulating tones of one or more desired frequencies to generate the tonal segments.
US09289345B2 Walking assist device
A walking assist device is capable of operating at an appropriate cycle in view of the motion cycle of a human being to be assisted while at the same time reducing the number of control parameters to be adjusted or set. A second phase oscillator, based on which the phase of the periodic operation of each actuator is controlled, is calculated on the basis of the difference between a first phase oscillator, which indicates a phase of the periodic motion of each thigh relative to the upper body of a human being, and the second phase oscillator, and an intrinsic angular velocity. A current intrinsic angular velocity is set by correcting a previous intrinsic angular velocity by an amount based on a previous difference between the first phase oscillator and the second phase oscillator such that the previous difference approaches a desired difference.
US09289340B2 Retractable side rail mounting assembly
A patient care bed includes a frame, a side rail, and a side rail mounting assembly. The side rail mounting assembly includes a rail-receiving member defining a passageway configured to releasably receive the side rail and a support rod fixedly engaged to and extending from the rail-receiving member. The support rod is slidable relative to the frame between a storage position, wherein the rail-receiving member is disposed within the frame, and a use position, wherein the rail-receiving member is disposed outside the frame. The support rod is rotatable relative to the frame between a storage orientation, wherein the rail-receiving member is horizontal, and a use orientation, wherein the rail-receiving member is vertical. The side rail mounting assembly is transitionable between a storage condition, corresponding to the storage position and orientation of the support rod, and a use condition, corresponding to the use position and orientation of the support rod.
US09289339B2 Personal mobility vehicle
A personal mobility vehicle comprising a platform (10) on which a user of the vehicle can stand, ground-engaging wheels (14, 15, 16) on which the platform (10) is supported, motor drive means, motor control means (20), a column (11) extending upwards from the platform (10) and a leg or thigh support rest (18) mounted on the column.
US09289336B2 Patient support with energy transfer
A patient support including a base; a patient support surface supported by the base; an electrically powered device; a rechargeable power storage device for powering the electrically powered device; and a receiving coil electrically coupled to the rechargeable power supply for inductive coupling with a transmitting coil. The receiving coil is for recharging the rechargeable power supply when the receiving coil is inductively coupled to the transmitting coil.
US09289332B2 Disposable absorbent pants with advantageous stretch and manufacturability features, and methods for manufacturing the same
A disposable absorbent pant that includes a central chassis and a belt structure is disclosed herein.
US09289329B1 Method for producing pant type diapers
A core forming unit feeds a core to a cutting unit, where a core is wrapped with a core topsheet and backsheet. The core insert is folded and a front wing web and a back wing web are coupled to the folded core. If a pant type diaper is desired, side seams of the front wing web and back wing web are bonded together at side seam regions. Next, portions of the front wing web and back wing web are folded over to create a compact product for packaging and shipment.
US09289328B2 Foam dressing with integral porous film
Wound dressings and wound inserts comprising a porous film layer and at least a channel, wound inserts of forming wound inserts comprising a porous film layer and at least a channel, and wound-treatment wound inserts.
US09289326B2 Reduced-pressure, wound-closure and treatment systems and methods
A reduced-pressure, wound closure system is presented that generates a closing force on a surface wound and optionally provides reduced pressure to a body cavity or tissue site. The sealed contracting member, when placed under reduced pressure, generates the closing force. One illustrative system includes a first attachment member and a second attachment member, a sealed contracting member coupled to the first attachment member and the second attachment member, and wherein the closing force is generated between the first attachment member and the second attachment member when reduced pressure is supplied to the sealed contracting member. Other systems and methods are presented.
US09289322B2 Ostomy appliance
An ostomy appliance comprising an adhesive wafer for attachment to the body, the wafer comprising a skin facing surface and a non skin-facing surface, the non skin-facing surface being provided with a backing layer, the skin facing surface of the wafer comprises a central area comprising a substantially non-absorbent protective adhesive, an intermediate area surrounding the central area, said area comprising a substantially non-absorbent soft adhesive, and an edge area surrounding the intermediate area, said edge area comprising a substantially non-absorbent protective adhesive.
US09289314B2 Intersomatic cage
The invention relates to an intersomatic cage comprising a body (3) and a part (2) that is designed to dilate the intersomatic space between two vertebrae (8, 8′) by rotating the cage so that the cage (1) can be inserted into the space. The body (3) has a prism shape with a substantially planar upper surface (6) which can bear against the superior vertebral endplate (8) and a substantially planar lower surface (6′) which can bear against the inferior vertebral endplate (8′).
US09289313B2 Insertion instrument for inserting socket insets into hip sockets for hip endoprostheses
An insertion instrument for instrumented insertion of a socket inset (4) with a spherical cap (20) into a hip socket (5) of a hip-joint prosthesis, having an impacting instrument (1) with a handle (7), at one end of which a holding tool for the socket inset (4) is located. In order to avoid tilting of the socket inset during insertion, it is proposed that the one end (8) of the impacting instrument (1) has a spherical shape and is part of the holding tool, and the holding tool furthermore comprises an impacting head (2), which is designed as a separate component and received the spherical end (8) of the impacting instrument (1) in an articulated manner, and an insertion aid (3), which is designed as a separate component and serves to hold the socket inset (4) on the outer geometry of the impacting head (2), and the impacting head (2) can be connected to the spherical end (8) to form a ball joint.
US09289309B2 Intervertebral implant
A vertebral implant for fusing adjacent vertebrae or for replacing vertebral bodies is disclosed. The implant is a biocompatble metal resorbable or radiolucent implant conforming substantially in size and shape with an end plate of a vertebra. The implant preferably has a wedge-shaped profile to restore disc height and the natural curvature of the spine. The top and bottom surfaces of the implant have areas with a plurality of teeth to resist expulsion and provide initial stability and areas devoid of any protrusions to receive implantation instrumentation. The implant also has a stackability feature. The implant provides initial stability needed for fusion without stress shielding.
US09289308B2 Articulating interbody cage and methods thereof
Disclosed herein are devices (100), systems and methods of use relating to articulating interbody cages. In one aspect, disclosed is an intervertebral device (100) for use in a human spine including an anterior end (104); a posterior end (102); and at least four peripheral walls (22,24,26). The peripheral walls (26) define an interior volume surrounding a midline of the device and include a superior wall (22), an inferior wall (24) and a pair of opposing, generally trapezoidal-shaped sidewalls. Each of the trapezoidal-shaped sidewalls (26) includes an internal hinge element (60) that is rotatable from a first configuration to at least a second configuration such that the device is expandable in first dimension. Each of the internal hinge elements includes an axis that is coplanar with the midline of the device.
US09289302B2 Mosaicplasty constructs
Various embodiments of mosaicplasty constructs and methods for implanting the constructs into anatomical structures. The mosaicplasty constructs may be formed from artificial materials and may include a hard articulating portion and a relatively softer elastic, support portion. The mosaicplasty constructs may include bone ingrowth materials to facilitate ingrowth of bone and other tissues into the construct. The mosaicplasty constructs may also be at least partially formed of hydrogel materials.
US09289292B2 Valve cuff support
A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent has a proximal end, a distal end and a plurality of cells, each cell being formed by a plurality of struts. A valve assembly is secured to the stent and includes a cuff and a plurality of leaflets. The plurality of leaflets are attached to the cuff adjacent an underwire that extends about the perimeter of the cuff.
US09289291B2 Valve prosthesis
The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ.
US09289290B2 Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features
A prosthetic heart valve is circumferentially collapsible for less invasive delivery into a patient. The valve re-expands to operating size at the implant site in the patient. A frame structure of the valve includes restraining structure that can help to push one or more of the patient's native heart valve leaflets radially outwardly so that this native leaflet tissue does not interfere with the operation or service life of the prosthetic valve.
US09289289B2 Sutureless anchoring device for cardiac valve prostheses
A device for anchoring a prosthetic heart valve on biological tissue, includes first and second anchoring assemblies, mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.
US09289288B2 Intraocular lens insertion device
An intraocular lens insertion device which dramatically reduces the possibility that a plunger damages an intraocular lens, and which can safely and surely insert an intraocular lens into an eye is provided. An intraocular lens insertion unit comprises a lens disposing part for disposing an intraocular lens, a plunger for pushing out the intraocular lens disposed at the lens disposing part, a transition part for deforming the intraocular lens pushed out by the plunger, and a nozzle for ejecting the deformed intraocular lens. The plunger has a lens contact part for contacting the outer edge of the intraocular lens, and a protrusive part for pushing the lens contact part downward the intraocular lens by the deformation of the intraocular lens, both lens contact part and protrusive part are provided at the leading end of the plunger.
US09289285B2 Device for implanting a system for loading a cruciate ligament in a knee joint
A device for implantation in a bone is disclosed, wherein this device is a component part of a system, for controlled loading of the reconstructure anterior crucual ligament (ACL) of a knee joint. The device may comprise an outer body, which is provided with a damping mechanism between a distal end and a proximal end. Arranged inside the damping mechanism there is at least one securing element for fixing at least one thread which, at the proximal end of the device, is guided out from the outer body through an aperture in the base.
US09289284B2 Ligament screw attachment device
A bone block assembly including a bone block having a proximal end, a distal end, a central axis defined therethrough, and a hole formed therethrough, and a threaded screw having a proximal end, a distal end, and a first eyelet formed on the proximal end of the threaded screw, the threaded screw configured to be received within the hole of the bone block. The first eyelet of the threaded screw is, at least partially, exposed on the proximal end of the bone block when the threaded screw is fully engaged with the bone block. The first eyelet of the threaded screw is configured to receive a suture.
US09289283B2 Tenodesis implant and inserter and methods for using same
The present invention provides a novel split barbed fixation device for tenodesis, soft tissue reattachment of tendons and ligaments to bones. The insertion device is adapted for an entirely arthroscopic approach while achieving fixation strength with ultimate pullout resistance comparable to interference screws. The device includes an integrated tendon grasper that provides for easy manipulation of the tendon arthroscopically while eliminating the need for external whip stitching of the tendon, thereby reducing preparation time. The device further includes elements that prevent the fixation implant from being destabilized or rotating during deployment and manipulation, including: a depth limiting sheath, a first implant retainer, a first implant retaining step, a tendon grasping needle tube, and an implant keyway for mating the implant to the tube. The implant itself comprises two separate portions mating along a diagonal and having barbed surface features in opposite directions, only one of which contacts the tendon.
US09289279B2 Apparatus and method for limiting surgical adhesions
A composite prosthesis and method for limiting the incidence of postoperative adhesions. The composite includes a non-inflammatory or coated mesh and a barrier material which prevents exposure of tissue elsewhere in the body to tissue covered by the composite prosthesis. The barrier material is absorbable which allows tissue through-growth and localization of the composite prosthetic. In use, the composite prosthesis is positioned over the tissue defect and may be positioned with the barrier material oriented against the tissue defect or repair site.
US09289270B2 Method and apparatus for performing a navigated procedure
A system can be used to navigate or guide an instrument or device into an anatomy of a patient. The navigation can occur with the use of image data acquired of the patient. The image data can be registered to the patient space for navigation. One or more tracking devices can be the associated with the patient and with guiding instruments for tracking guiding devices relative to the patient.
US09289267B2 Method and apparatus for minimally invasive surgery using endoscopes
A method and apparatus for presenting three-dimensional data to a physician is provided to facilitate the flexible navigation of an endoscope and surgical instruments with respect to anatomical structures. In accordance with a first embodiment a first set of data corresponding to a three dimensional model of a patient's anatomy is received. This three-dimensional model may be rendered from images taken in CT or MRI scanning, as discussed above. In accordance with this embodiment, this model is then combined with a second set of data corresponding to a view obtained from an endoscope. In another embodiment, the view from the illustrative endoscope is displayed as an inset image on the display of the three-dimensional image. In yet another embodiment, the three-dimensional image comprises a graphical representation of at least a first surgical instrument, such as said endoscope. The surgeon may select among various combinations of views and may zoom in or out from any particular view.
US09289266B2 On-axis drive systems and methods
Described herein are drive systems and methods. One exemplary system includes a tool having a proximal handle and a catheter body. The tool can be mated with a rail and the rail mated with a frame. The connection between the tool and rail and/or the rail and frame can allow relative movement of the tool with respect to the frame, a patient, and/or a point of reference. In one exemplary configuration the handle of the tool rotates around an axis that corresponds to a portion of the catheter body, such that rotational movement of the handle has a minimal impact on longitudinal movement and/or position of a distal end of the tool.
US09289265B2 MRI-compatible, integrated force and torque sensors and systems that incorporate the sensors
A magnetic resonance imaging (MRI) compatible sensor for measuring torque with respect to an axis of rotation in conjunction with an applied linear force includes a shaft arranged in a longitudinal direction substantially along the axis of rotation, a base component arranged along the axis of rotation and displaced with respect to the shaft, a torque detector assembly configured to be coupled to rotational motion of the shaft about the axis of rotation relative to the base component, and a linear-force detector assembly configured to be coupled to linear motion of the shaft from a force applied in a direction substantially coincident with the axis of rotation relative to the base component. The torque detector assembly and the linear-force detector assembly are substantially de-coupled from each other such that torque measurements are substantially independent of linear force measurements. The MRI compatible sensor consists essentially of MRI compatible materials.
US09289256B2 Surgical end effectors having angled tissue-contacting surfaces
Surgical end effectors are disclosed having angled tissue-contacting surfaces. The end effectors may have a first jaw member that is movable relative to a second jaw member between an open position and a closed position. The first jaw member may have a first positively-angled tissue-contacting surface. The second jaw member may have a second positively-angled tissue-contacting surface. At least one of the jaw members may have at least one active electrode configured to deliver RF energy to tissue located between the first jaw member and the second jaw member when in the closed position.
US09289253B2 Patient-specific shoulder guide
An orthopedic device for a shoulder joint includes a patient-specific alignment guide. The alignment guide includes a cap having a three-dimensional engagement surface customized in a pre-operative plan by computer imaging to be complementary and closely mate and conform to a humeral head of a proximal humerus of a patient. The alignment guide includes a tubular element extending from the cap and defining a longitudinal guiding bore for guiding an alignment pin at a patient-specific position and orientation determined in the pre-operative plan, and an orientation feature on the cap. The orientation feature is designed to orient the cap relative to the humeral head when the orientation feature is aligned with a landmark of the proximal humerus.
US09289249B2 Bone anchors and surgical instruments with integrated guide tips
Bone anchors and surgical instruments (e.g., bone taps, drivers, etc.) are disclosed herein that include integrated guide tips. Use of these anchors or instruments can eliminate one or more of the steps in a conventional bone anchor installation procedure, improving surgical efficiency and safety. For example, a surgical instrument can include a guide projection configured for insertion through a cannulation formed in a bone anchor when the surgical instrument is coupled to the bone anchor. The surgical instrument can also include various mechanisms for adjusting the position of the guide projection relative to the bone anchor. The guide projection can replace the needle, stylet, and guidewire used in typical insertion procedures. The bone anchor can also include integrated tapping features to eliminate the need for a separate bone tap instrument. Thus, in some embodiments, targeting, tapping, and driving the bone anchor can be performed in a single step.
US09289247B2 Surgical tool holder
A surgical tool holder includes a flange comprising a body defining a first surface and a second surface, a first end and second end. The second surface defines a first opening configured for disposal of a cannula, wherein the first end of the flange is configured to engage at least a portion of skin of a patient to prevent the cannula from moving into the patient.
US09289245B2 Locking assembly for a polyaxial bone anchoring device
A locking assembly for securing a rod in a polyaxial bone anchoring device includes a first locking element having a first end, a second end, an outer surface with an external advancement structure, an inner wall, an internal advancement structure on the inner wall, and an engagement portion for a tool, and a second locking element having a first end configured to be oriented towards the first end of the first locking element, an opposite second end, an outer surface with an external advancement structure configured to cooperate with the internal advancement structure of the first locking element, and a portion at the second end having a width greater than a greatest width of the external advancement structure of the second locking element, wherein the second locking element is configured to move axially relative to the bone anchoring device at a speed different than the first locking element.
US09289243B2 Methods for correcting spinal deformities
The present application discloses methods for treating spinal deformities. One embodiment includes inserting an elongated corrective member into the patient. During insertion, the corrective member is operatively attached to a first vertebral member that applies a first corrective force to correct a first vertebral member alignment. The corrective member is further inserted into the patient and subsequently operatively attached to a second vertebral member that applies a second corrective force to correct a second vertebral member alignment. The corrective member is further inserted and subsequently operatively attached to a third vertebral member that applies a third corrective force to correct a third vertebral member alignment. The embodiment may further include operatively attaching the corrective member to additional vertebral members to correct further misalignment. In one embodiment, a second member is attached to the vertebral members after they have been aligned to maintain the alignment.
US09289242B2 Internal pedicle insulator apparatus and method of use
Internal pedicle insulator apparatuses and methods are provided. A representative method includes: providing an internal pedicle insulator implant; inserting the implant into a pedicle such that the implant is positioned between a nerve and material that is to be applied in a vicinity of the nerve; applying the material in the vicinity of the nerve; and using the implant to prevent the material from contacting the nerve.
US09289241B2 Craniotomy closures
Craniotomy closures comprising surgical fasteners are described for use in reattaching a skull flap removed from the skull of a patient during brain surgery. Methods of using the same are also described. Surgical strips used in combination with the fasteners are shaped to follow the perimeter contour of the skull flap. The craniotomy closures are designed to encourage bone growth and healing of the skull flap and they can be used to deliver medication and bone growth enhancement materials to the surgical site.
US09289240B2 Flexible elongated chain implant and method of supporting body tissue with same
Implants and methods for augmentation of the disc space between two vertebral bodies to treat disease or abnormal pathology conditions in spinal applications. The implant includes a chain of biocompatible material suitable for insertion into a disc space between two adjacent vertebral bodies in a patient's spinal column, wherein the spinal disc space has a transverse plane. The chain comprises a plurality of adjacent bodies having a height configured to reside within the disc space between two adjacent vertebral bodies and a length configured to reside in the disc space between two adjacent vertebral bodies when the chain is curved in an orientation substantially along the transverse plane of the spinal disc space.
US09289232B2 Soft tissue tunneling device
A tissue tunneling device is configured to be delivered within the body. The tunneling device includes a shaft with a blunt distal end to prevent coring or other damage to tissue during the delivery of the tunneling device. In some arrangements, the shaft includes one or more lumen, through which medication or another fluid may be administered. An anesthetic or other pain relieving medication may be delivered through the lumen to lessen the discomfort of delivering the tunneling device to the desired anatomical site. The shaft may also include a retractable needle for facilitating the advancement of the tunneling device through skin or other tissue. The shaft may also be provided with an outer sheath, which may be left within the anatomy after the tunneling device has been removed. The shaft may be malleable for custom-shaping the tunneling device prior to and/or during delivery.
US09289230B2 Rotational atherectomy device with a system of eccentric abrading heads
The invention provides a rotational atherectomy device having, in various embodiments, a flexible, elongated, rotatable drive shaft with a system of eccentric abrading heads attached thereto. At least part of the eccentric enlarged abrading heads in the system have a tissue removing surface—the abrading heads may be at least partially hollow. Preferably the abrading heads have centers of mass spaced radially from the rotational axis of the drive shaft, facilitating the ability of the system of abrading heads to work together to open the stenotic lesion to a diameter larger than the outer resting diameter of the abrading heads when operated at high speeds. Therefore, certain embodiments comprise a system having unbalanced centers of mass to not only stimulate greater rotational diameters but also arranged in a manner whereby a debris-removing augering effect occurs. Other embodiments may comprise systems having abrading heads with balanced centers of mass.
US09289229B2 Devices and methods for removing stenotic lesions from vessels
The present application provides various devices, systems, and methods for removing stenotic lesions from vessels. In at least one embodiment of an exemplary device of the present disclosure, the device comprises at least one treatment portion operable to remove at least part of a stenotic lesion, and at least one sizing portion operable to measure a first luminal size parameter when positioned and operated at a first location and further operable to measure a second luminal size parameter when positioned and operated at a second location, wherein the device comprises an elongated body selected from the group consisting of a catheter and a wire.
US09289226B2 Retractable separating systems and methods
A method for detaching an object from a patient includes providing a tool having a sheath, and a separating assembly operably coupled to a distal end of the sheath. The separating assembly includes a separator moveably coupled to a tip via a threadable connection. The separating assembly is placed near patient tissue that is attached to the object, the sheath is rotated to move the separator distal to the tip, and the separator is applied to the patient tissue that is attached to the object, so as to separate the tissue. A separating system includes a sheath, and a separator threadably coupled with a distal end of the sheath. The separator is adapted to switch between a first configuration where a separating mechanism is deployed, and a second configuration where the separating mechanism is undeployed.
US09289224B2 Shock wave valvuloplasty device with moveable shock wave generator
A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the valve. The shock wave generator is moveable within the balloon to vary shock wave impingement on the valve.
US09289223B2 Surgical guide instrument and system for ACL reconstruction and method of using same
A system for performing anterior cruciate ligament reconstructions is provided. The system includes a surgical guide instrument defining an elongate body having a hand-graspable handle and a head section including a distal phalange and a proximal open-faced slot. The distal phalange is contoured to anatomically conform to the femur and includes a notch section engageable with the intercondylar notch. The open-faced slot includes a stop member. The system further includes a guide wire operably receivable by a guide wire sheath to form a guide wire assembly. The guide wire assembly is received by the open-faced slot wherein the stop member is structured to stop the sheath from exiting the slot. The surgical guide instrument can direct the guide wire to an anatomic position on the femur and ensure a safe and usable femoral tunnel.
US09289222B2 Apparatus and method for repairing bone defects
A system can include a sizing and drill guide having a body with a bone engaging side, an opposite side and first and second guide holes. The bone engaging side can include a profile for positioning in the trochlear groove and the guide holes can include axes that can be orientated at an acute angle. Retaining members can be positioned in bores formed in the body and can fix the guide to the femur. A cutting device can be guided by the guide holes and can include a bone engaging end having a body and first and second cutting portions. The first cutting portion can have a smaller diameter than the second cutting portion and can be axially spaced apart therefrom so as to form a stepped pocket in the femur. The body can include an outer diameter sized to be complimentary to an inner diameter of the guide holes.
US09289220B2 Intramedullary fixation assembly and method of use
An intramedullary fixation assembly for bone fixation includes a first construct. The first construct includes a first tapered screw member fixated into a subchondral bone. The first tapered screw member is aligned along a first longitudinal axis and has a first head portion comprising a first aperture and a first shaft extending from the first head portion. Moreover, the first longitudinal axis of the first tapered screw member is aligned substantially parallel to an articular surface of a bone. The first construct also includes a first lag screw member aligned along a second longitudinal axis. The first lag screw member has a first bulbous portion and a second shaft extending from the first bulbous portion, wherein the first lag screw member is coupled to the first tapered screw member, and further wherein the second longitudinal axis of the first lag screw member is aligned generally along the length of the bone.
US09289218B2 Osteotome extractor
A surgical tool, enabling extraction of a prosthesis from a bony implantation site of that prosthesis, defines a proximo-distal axis and includes a distal end head adapted both to cut at least partially the bonding interface between the prosthesis and the bony material of the implantation site and to fix itself to the prosthesis by rotation centered on the proximo-distal axis, according to embodiments of the present invention.
US09289215B2 Implant including a coil and a stretch-resistant member
This invention is directed to implantable coils and, more particularly, to a coil implant having a stretch-resistant member internal to the coil. The implant of the invention is able to freely articulate and torque prior to delivery. Once delivered, the implant is no longer stretch resistant and is therefore able to substantially conform to the vascular site.
US09289214B2 Mounting tool for anastomosis device
A mounting tool for mounting a flexible ring-shaped part of an anastomotic device on a rigid part of an anstomotic device is provided. The tool comprises a receiving portion (104) in a distal end of the mounting tool for receiving the flexible part thereat and a handle portion (103) proximally of said receiving portion (104). Said receiving portion (104) comprises an elongated tubular sheet element (101), and a tubular displacement element (201), arranged within the sheet element (101) to be longitudinally displaceable in relation to the sheet element (101), such that a shelf (401) is obtained circumferentially of the tubular displacement element (106) and distally of the sheet element (101). The shelf (401) is configured to receive the flexible part. A mounting tool for receiving a flexible ring-shaped part of an anastomotic device on a rigid part of an anstomotic device is also provided. This tool comprises a longitudinal guiding element (801) for passing through a central passage or lumen in a mounting tool according to above, and a connection plate (802) arranged distally on the guiding element (801). The connection plate (802) is configured to connect to a rigid part of an anstomotic device. A kit is also provided.
US09289213B2 Multiple clip applier apparatus and method
A surgical clip applier includes a train of clips disposed in a plane with a single clip removed from the train of clips and disposed in a staging position. A pair of jaws are adapted to receive the single clip from the staging position by operation of a jaw loader moveable outside the plane of the train of clips. In an associate method, a handle assembly is provided which is moveable in an open stroke and a closed stroke. A source of surgical clips are provided along with a pair of jaws which are adapted to receive one of the clips as the handle assembly is moved in an open stroke, the jaws are open to receive the clip. Following the opening of the jaws, a jaw loader is extended to a position between the jaws to move the clip into the jaws. The handle assembly is moveable in a closed stroke during which the jaws are closed to crimp the clip. Prior to this closing of the jaws, the jaw loader is retracted from the position between the jaws leaving the clip in the jaws.
US09289210B2 Surgical stapler with apparatus for adjusting staple height
A surgical stapling instrument including a staple sled which can be advanced and/or retracted relative to first and second jaw members, wherein the staple sled can be configured to deploy staples from a staple cartridge in one of the first and second jaw members. In at least one embodiment, the other of the first and second jaw members can include an anvil having at least one forming surface which can be configured to deform the staples as they are deployed from the staple cartridge. In at least one form of the invention, the anvil can be movably adjustable relative to the staple cartridge in order to adjust the distance in which the staples are deformed. In various embodiments, the anvil can be adjusted by a slidable adjusting plate and/or a rotatable cam.
US09289204B2 Insertion device and method for delivery of a mesh carrier
An insertion device includes an elongate member and a stylet. The elongate member has a proximal end portion, a distal end portion, and defines a lumen therethrough. The stylet has a proximal end portion, a distal end portion, and is slidably coupled to the elongate member. The stylet is configured to move from a first position to a second position with respect to the elongate member. The proximal end portion of the stylet is configured to removably couple a mesh carrier thereto. A portion of the proximal end portion of the stylet is disposed outside of the lumen of the elongate member when the stylet is in its first position and is disposed within the lumen when the stylet is in its second position.
US09289203B2 Method and apparatus to reload suture anchors
A drill guide assembly for drilling a bone hole and implanting a suture anchor in the bone hole. The assembly includes a drill guide and a suture anchor. The drill guide includes a sidewall extending between a proximal end and a distal end of the drill guide. The sidewall defines a center cannulation configured to receive a drill. The suture anchor retention portion of the drill guide is configured to support a suture anchor for coupling with an inserter device pushed through the drill guide to implant the suture anchor in the bone hole.
US09289202B2 Suture-retaining device and anchor
A rotator cuff tendon injury is repaired using a flexible fastener and an anchor. The flexible fastener is attached to the rotator cuff tendon and also secured to the anchor. The anchor is attached to or supported by various locations on the humerus other than the humeral head, to provide a robust means for holding the rotator cuff tendon in the desired position against the humeral head.
US09289201B2 Medical device for repair of tissue and method for implantation and fixation
The present invention relates to medical devices for repairing tissue and more specifically to devices which facilitate tissue regeneration and to surgical methods for the implantation and fixation of such devices. In one embodiment, the medical device is an elongate conduit that includes a longitudinal bore extending therethrough to facilitate the transfer of blood from a vascular region of tissue to a tear or damaged area located in an avascular and/or semi-vascular region of tissue. A filament and/or filaments are attached to the conduit and are positioned to secure the conduit and fixate the adjacent tear walls in mutual engagement. In another embodiment, a series of conduits are connected via a filament and/or filaments to facilitate the implantation of multiple conduits.
US09289197B2 Tissue puncture closure device with automatic torque sensing tamping system
Methods and apparatus for sealing a puncture or incision formed percutaneously in tissue separating two internal portions of the body of a living being with an anchor, a sealing plug and a filament connecting the anchor and sealing plug are disclosed. The methods and apparatus provide for automatic tamping of the sealing plug. In addition, torque required to tamp the sealing plug is automatically sensed and gear ratios of an automatic tamping device are automatically changed in response to sensed changes in torque. A planetary transmission may be used to automatically change gear ratios in response to the changes in torque.
US09289196B2 Hemostatic substance with a coating
A hemostatic device includes a dissolvable coating and a hemostatic substance enclosed within the coating. The device can have, for example, a generally spherical shape. The hemostatic substance can be particles that take any shape, such as spherical, flat sheets, cubes, or other regular or irregular shapes of any size or volume that can be used on or within a body.
US09289192B2 Biopsy needle actuator assembly
A biopsy needle actuator assembly used with a biopsy needle for excising a tissue specimen from a target tissue in an animal includes a counter assembly for tracking the individual biopsy event associated with the actuator assembly, and tracking the cumulative number of firings of the actuator assembly to ensure the actuator assembly is replaced prior to failure. The counter assembly registers movement of the biopsy needle during use, aids an operator in proper identification of the biopsy specimen during a biopsy event, and aids the user in correlating the location and orientation of pathological findings of the biopsy specimen in the target tissue in vivo to aid in treatment of the target tissue.
US09289183B2 Interactive display of computer aided detection results in combination with quantitative prompts
Methods and related systems provide an interactive user interface in which CAD results are displayed in such a way that they may be used for both interpretation of detected abnormalities and for avoiding perceptual oversights. The output of a (multi-view) computer aided detection system is presented to the reader of a screening case in two phases: (1) an interactive phase, and (2) a prompting phase. In the first phase the reader can probe image locations for CAD information. In the second phase regions identified as relevant by the CAD system and not yet probed by the reader are prompted or displayed to the user, as these may have been overlooked by the reader. The CAD results can be calibrated to a probability of malignancy.