Document Document Title
US09175344B2 Structure with nanopore and apparatus for determining sequences of nucleic acids including the same
Disclosed are a structure with a nanopore and an apparatus for determining sequences of nucleic acids including the structure, the structure including three or more structures having facing surfaces, a plurality of oligonucleotides attached at one ends thereof to the surfaces, and a pore formed between the structures to which the plurality of oligonucleotides are bound, and allowing a pore of a desired size to be precisely formed by adjusting the length of a plurality of oligonucleotides.
US09175343B2 Methods and processes for calling bases in sequence by incorporation methods
Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.
US09175340B2 Reactivity-dependent and interaction-dependent PCR
Methods, reagents, compositions, and kits for reactivity-dependent polymerase chain reaction (RD-PCR) and interaction-dependent polymerase chain reaction (ID-PCR) are provided herein. RD-PCR is a technique useful for determining whether a reactive moiety can form a covalent bond to a target reactive moiety, for example, in screening a library of candidate reactive moieties for reactivity with a target reactive moiety, and in identifying an enzyme substrate, for example, in protease substrate profiling. ID-PCR is a technique useful for determining whether a ligand can non-covalently bind to a target molecule, for example, in screening a library of candidate ligands for non-covalent interaction with a target molecule. RD-PCR and ID-PCR are also useful in detecting the presence of an analyte or an environmental condition.
US09175337B2 Methods for amplifying nucleic acid using tag-mediated displacement
Disclosed are methods for amplifying a nucleic acid target region using an amplification oligomer comprising a target-binding segment and a heterologous displacer tag situated 5′ to the target-binding segment. Initiation of an amplification reaction from the tagged amplification oligomer produces an amplicon comprising the displacer tag, such that once the complement of the displacer tag has been incorporated into a second amplicon, a displacer oligonucleotide having a sequence substantially corresponding to the displacer tag sequence is used to participate in subsequent rounds of amplification for displacement of an extension product primed from a site within the second amplicon 5′ to the displacer priming site. Also disclosed are related kits and reaction mixtures comprising the displacer-tagged amplification oligomer and corresponding displacer oligonucleotide.
US09175330B2 Method for screening and quantifying isoprene biosynthesis enzyme activity
A method of performing high-throughput screening of various enzymatic activities with high sensitivity using artificial genetic circuits is provided. Particularly, the invention is screening and quantifying the activity of isoprene biosynthesis enzymes using an artificial genetic circuit capable of sensing isoprene. The artificial genetic circuit comprises an isoprene-sensing transcriptional regulator which recognizes isoprene, at least one reporter gene, a isoprene-sensing transcriptional regulator binding region and promoters for genes encoding isoprene-sensing transcriptional regulators and reporter proteins.The artificial genetic circuit detects isoprene liberated from many enzymatic reactions and measures the activity of reporter genes. This system is widely applicable for high throughput and quantitative screening of isoprene biosynthesis enzymes and MEP/MVA pathway enzymes.Therefore, the invention can be advantageously used in the protein engineering technology for enzyme modification. Particularly, it can provide a quantitative investigation of enzymatic activity, and thus can be applied to molecular evolution technology.
US09175325B2 Global amplification using a randomly primed composite primer
The invention relates to the field of polynucleotide amplification. More particularly, the invention provides methods, compositions and kits for amplification of (i.e., making multiple copies of) a multiplicity of different polynucleotide template sequences using a randomly primed RNA/DNA composite primer.
US09175320B2 Processes for the preparation of (R)-2-(7-4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[B]indol-3-yl)acetic acid and salts thereof
The present invention relates to processes and intermediates useful in the preparation of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid of Formula (Ia) and salts thereof, an S1P1 receptor modulator that is useful in the treatment of S1P1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, autoimmune diseases and disorders, inflammatory diseases and disorders (e.g., acute and chronic inflammatory conditions), cancer, and conditions characterized by an underlying defect in vascular integrity or that are associated with angiogenesis such as may be pathologic (e.g., as may occur in inflammation, tumor development and atherosclerosis).
US09175317B2 Method for producing a polyhydroxyalkanoate using a microorganism belonging to the genus Cupriavidus
The present invention provides a microorganism that synthesizes a high-molecular-weight PHA, and a method for producing a high-molecular-weight PHA, which have a productivity of at least 100 g/L. The provision is achieved by controlling the specific activity of a PHA synthase in cells of a microorganism that belongs to the genus Cupriavidus and is capable of producing a PHA, to 0.1 U/mg-protein at most. The microorganism and the method enable industrially efficient production of a PHA with a weight average molecular weight of at least 4,000,000.
US09175314B2 Anaerobic digestion with supercritical water hydrolysis as pretreatment
An hydrolysis stage of an anaerobic digestion (AD) process includes supercritical treatment in a reactor (R1). The treatment may use sub-stoichiometric oxygen so that there is not full oxidation. Effluent from the supercritical treatment may be used to pre-heat the organic matter in-feed to the supercritical treatment. There may be a second supercritical treatment in a second reactor (R2). This may have full stoichiometric oxygen, to oxidize the solids from the first reactor (R1) effluent. Furthermore, it provides heat for pre-heating its own in-feed and also that for the first reactor (R1). The output from the hydrolysis may be only clarified liquid, leading to particularly efficient downstream AD processes. The second supercritical treatment rector may oxidize also fed-back solids from the final stage of the AD.
US09175312B2 Vectors harboring toxic genes, methods and uses therefor
The present disclosure describes nucleic acids, and viruses comprising such nucleic acids, for growing a toxic gene in an insect cell. These nucleic acids comprise a sequence encoding a toxic polypeptide, and an intron that interrupts the sequence, whereby the intron is spliced in mammalian cells but not in insect cells. Infection of mammalian cells but not insect cells with the nucleic acids or viruses can lead to expression of toxic levels of the toxic polypeptide in mammalian cells but not in insect cells. Viruses, such as an AAV or a baculovirus comprising a nucleic acid can be grown in insect cell lines in vitro and can be administered to a subject in need of therapy, such as a subject in need of cancer therapy.
US09175311B2 Polycistronic vector for human induced pluripotent stem cell production
Methods of producing induced pluripotent stem (iPS) cells are provided. For example, a method of producing an iPS cell from a differentiated cell, which includes transforming the differentiated cell with a first vector comprising a nucleic acid sequence comprising a nucleic acid sequence encoding an Oct4, a nucleic acid sequence encoding a Sox2, and a nucleic acid sequence encoding a Klf4. Each of the nucleic acid sequences are separated from each other by a first and second viral 2A sequence. The method described can further comprise culturing the transformed cell under conditions that allow for the production of an iPS cell and isolating the cultured iPS cell.
US09175309B2 Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comprising said recombinant adenovirus
Disclosed is a recombinant adenovirus with a protein containing a VSV-G epitope derived from vesicular stomatitis virus (VSV). Also, the present invention discloses a pharmaceutical composition comprising such a recombinant adenovirus and a pharmaceutically acceptable carrier. Further, the present invention discloses a recombinant plasmid capable of expressing the recombinant adenovirus and a host cell transformed with the recombinant adenovirus.
US09175304B2 Drought tolerant plants and related constructs and methods involving genes encoding self-incompatibility protein related polypeptides
Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes an SIPR polypeptide.
US09175301B2 Use of dimerization domain component stacks to modulate plant architecture
This invention provides means for altering the harvest index of crop plants by modulating the expression of transgenic genes using dimerization domain and component stacks, thereby modulating plant architecture. The transgene/dimerization domain stacks are provided in a single transformation vector unit and are used to modulate plant growth, yield, and harvest index in plants.
US09175298B2 Compositions for enhancing segregation of transgenes in plants
The compositions and methods are provided that enhance the selection of transgenic plants having two T-DNA molecules integrated into a plant genome at different physical and genetic loci. The compositions are DNA constructs that comprise novel arrangements of T-DNA molecules containing genes of interest, positive selectable marker genes, and conditional lethal genes. The methods disclosed herein comprises transforming a plant cell to comprise the DNA constructs of the present invention, regenerating the plant cell into a plant and identifying independent transgene loci, where the selectable marker genes or transgenic elements can be segregated in the progeny.
US09175290B2 Compositions and methods for inhibiting expression of TMPRSS6 gene
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the TMPRSS6 gene, and methods of using such dsRNA compositions to inhibit expression of TMPRSS6.
US09175287B2 In vivo production of small interfering RNAs that mediate gene silencing
The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By introducing nucleic acid molecules that encode these engineered RNA precursors into cells in vivo with appropriate regulatory sequences, expression of the engineered RNA precursors can be selectively controlled both temporally and spatially, i.e., at particular times and/or in particular tissues, organs, or cells.
US09175285B2 Potent non-urea inhibitors of soluble epdxide hydrolase
The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
US09175274B1 High activity mutants of butyrylcholinesterase for cocaine hydrolysis
Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (−)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (−)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.
US09175271B2 Lipid acyltransferase proteins and methods of making them
The present invention provides a method for preparing a variant lipid acyltransferase enzyme by expressing a nucleotide sequence encoding a lipid acyltransferase which may comprise at least one modification at a position(s) which corresponds in the encoded amino acid sequence to an amino acid(s) located in a) the canyon region of the enzyme (i.e. preferably amino acid residues 31, 27, 85, 86, 119, and 120); and/or b) insertion site 1 (i.e. amino acid residues 22-36) and/or c) insertion site 2 (i.e. amino acid residues 74-88), wherein the canyon region, insertion site 1 and/or insertion site 2 are defined as that region which when aligned based on primary or tertiary structure corresponds to the canyon region, insertion site 1 or insertion site 2 (or the corresponding amino acid residues taught above) of the enzyme shown herein as SEQ ID No. 16 or 6 in a host organism.
US09175270B2 Method of modifying a yeast cell for the production of ethanol
The invention relates to a method of modifying a yeast cell for the production of ethanol. According to some embodiments of the invention, the activity of the Gpd1 protein and/or the Gpd2 protein is reduced.
US09175263B2 Methods and compositions for targeting progenitor cell lines
The invention provides methods, compositions and kits for the identification and enrichment of progenitor cell lines obtained from pluripotent stem cells.
US09175257B2 Yeast strains for producing alcohol
The present invention relates to novel stable yeast strains, to a novel method for obtaining such strains, and to a novel method for evaluating the stability of a yeast strain. The present invention also relates to the yeasts obtained from these novel stable yeast strains, and to the use thereof for producing alcohol.
US09175255B2 Method of separating cells and separation apparatus
A method and apparatus for discriminating and separating only specific cells in cell samples is provided. The cell separation operation includes inserting a needle-shaped body, on which a substance that selectively binds to a marker substance within each target cell has been immobilized, into each of the cell samples on a substrate, thereby causing the marker substance within each target cell in the cell samples to bind to the needle-shaped body through the substance that selectively binds to the marker substance, and then, pulling up the needle-shaped body. The binding force between the needle-shaped body and each target cell when the marker substance within each target cell has bound to the needle-shaped body is made greater than an adhesion force of each of the cell samples to the substrate, so that only target cells each containing the marker substance are pulled up and separated from the substrate.
US09175254B2 Enhanced oxygen cell culture platforms
Provided is a cell culture apparatus for culturing cells, that provides enhanced oxygen delivery and supply to cells without the need for stirring or sparging. Oxygen diffusion occurs on both sides of the culture vessel, top and bottom. A gas-permeable membrane that includes perfluorocarbons or fluorocarbon derivatives (e.g., fluorinated silane, partially fluorinated silane) in its composition allows for the rapid, enhanced and uniform transfer of oxygen between the environment of cells or tissues contained in the cell culture container apparatus and the atmosphere of the incubator in which the cell culture apparatus is incubated.
US09175252B2 Photobioreactor and method for processing polluted air
A photobioreactor (100) for use in treating polluted air and producing biomass may comprise, at least in part, a generally vertical tube or fluidic pathway (102), a generally vertical helical tube or fluidic pathway (104) having a light source (106) partially positioned within the helical fluidic pathway (104), a head cap assembly (108), and a base assembly (110). In one illustrative example, the light source (106) may be a light emitting diode (LED) or a plurality of light emitting diodes (LEDs). By one approach, a gas diffusion apparatus (112) is located at the base assembly (110) adjacent the generally vertical fluidic pathway (102).
US09175251B2 Automatic detergent dishwashing composition
An automatic dishwashing detergent composition in unit dose form wherein the composition comprises at least about 0.2 mg of active starch degrading enzyme per gram of composition and wherein the weight of the composition is less than about 25 grams.
US09175245B2 Fatty amides and derivatives from natural oil metathesis
Fatty amide compositions and their derivatives are disclosed. The fatty amides comprise a reaction product of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with a primary or secondary amine. Derivatives made by reducing, quaternizing, sulfonating, alkoxylating, sulfating, and sulfitating the fatty amide are also included. The amine reactant can be diethylenetriamine or (2-aminoethyl)ethanolamine, which provide imidazoline amides or esters, respectively. In one aspect, the ester derivative of the C10-C17 monounsaturated acid or octadecene-1,18-dioic acid is a lower alkyl ester. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin. The compositions are valuable for cleaners, fabric treatment, hair conditioning, personal care, antimicrobial compositions, agricultural uses, and oil field applications.
US09175243B2 Stripping composition for a mold for making a composite material part, and method of preparing
A stripping composition, and a method of making the stripping composition. The stripping composition including 100 parts by weight of a base ingredient consisting in epoxy polydimethylsiloxane, 0.5 to 10 parts by weight of a polymerization agent for polymerizing the base ingredient and constituted by a diaryliodonium salt, not more than 30 parts by weight of an anti-adhesion modulator constituted by a silicone polymer; and not more than 40 parts by weight of an anti-stick agent making the composition less tacky prior to polymerization and constituted by at least one vinyl ether compound.
US09175236B2 Lubricating oil composition and method for use with low sulfur marine residual fuel
This invention describes novel trunk piston engine lubricating oil compositions for use in trunk piston engines operating on low sulfur marine residual fuels, as well as methods for lubricating trunk piston engines, methods of using the trunk piston lubricating oil compositions, and methods of making thereof.
US09175231B2 Methods of refining natural oils and methods of producing fuel compositions
A method of refining a natural oil includes: (a) providing a feedstock that includes a natural oil; (b) reacting the feedstock in the presence of a metathesis catalyst to form a metathesized product that includes olefins and esters; (c) passivating residual metathesis catalyst with an agent selected from the group consisting of phosphorous acid, phosphinic acid, and a combination thereof; (d) separating the olefins in the metathesized product from the esters in the metathesized product; and (e) transesterifying the esters in the presence of an alcohol to form a transesterified product and/or hydrogenating the olefins to form a fully or partially saturated hydrogenated product. Methods for suppressing isomerization of olefin metathesis products produced in a metathesis reaction, and methods of producing fuel compositions are described.
US09175228B2 Process and apparatus for purifying material of biological origin
The present invention relates to a process and an apparatus for purifying a mixture of terpene material and tall oil material for the production of biofuels and components thereof. The present invention relates further to hydroprocessing of the purified material to obtain biofuels and components thereof.
US09175225B2 Shifting mechanisms for fluid jet decoking tools
A mode shifting apparatus for a decoking tool is described herein. A diversion plate can be used to provide selective delivery of a pressurized decoking fluid to one or the other of nozzles in the tool. The mode shifting apparatus can be used to switch between a cutting mode of operation and a drilling mode of operation by rotation of the diversion plate, where a biasing force causes the diversion plate to unseat itself from an adjacent surface of the tool in order to reduce friction forces between them.
US09175224B2 Gasifying apparatus with variable gasifier and used as both power generator and combustion boiler, and method of driving the same
A gasifying apparatus including a variable gasifier and used as both a power generator and a combustion boiler and a method of driving the same are disclosed. A combustion boiler and a generator engine, driven with synthesis gas, are associated with a single gasifier, and the gasifying apparatus produces synthesis gas proper to a technical field of the gasifier by selectively applying an upflow gasifier and a downflow gasifier according to the technical field of the gasifier.
US09175219B2 Compounds for a liquid crystalline medium and use thereof for high frequency components
The present invention relates to compounds containing at least three ring systems, at least one of which is a 2,6-naphthylene group, and two unsaturated bridging groups between the ring systems, and to the use of the compounds for high-frequency components, in particular antennae, especially for the gigahertz region. The liquid-crystalline media comprising these compounds serve, for example, for the phase shifting of microwaves for tuneable ‘phased-array’ antennae.
US09175217B2 Wet etchants including at least one fluorosurfactant etch blocker
Methods for preventing isotropic removal of materials at corners faulted by seams, keyholes, and other anomalies in films or other structures include use of etch blockers to cover or coat such corners. This covering or coating prevents exposure of the corners to isotropic etch solutions and cleaning solutions and, thus, prevents higher material removal rates at the corners than at smoother areas of the structure or film. Solutions, including wet etchants and cleaning solutions, that include at least one type of etch blocker are also disclosed, as are systems for preventing higher rates of material removal at corners formed by seams, crevices, or recesses in a film or other structure. Semiconductor device structures in which etch blockers are located so as to prevent isotropic etchants from removing material from corners of seams, crevices, or recesses of a film or other structure at undesirably high rates are also disclosed.
US09175216B2 Ceramic scintillator body and scintillation device
A ceramic scintillator body includes a polycrystalline ceramic scintillating material having a substantially cubic crystallographic structure. The polycrystalline ceramic scintillating material has a chemical composition represented by a general formula LU(2-x)GdxO3:Ac, where x is greater than zero and less than two, and where Ac is an activator.
US09175213B2 Light-emitting element
A light-emitting element having high external quantum efficiency is provided. A light-emitting element having low drive voltage is provided. Provided is a light-emitting element which includes a light-emitting layer containing a phosphorescent compound, a first organic compound, and a second organic compound between a pair of electrodes. A combination of the first organic compound and the second organic compound forms an exciplex (excited complex). An emission spectrum of the exciplex overlaps with an absorption band located on the longest wavelength side of an absorption spectrum of the phosphorescent compound. A peak wavelength of the emission spectrum of the exciplex is longer than or equal to a peak wavelength of the absorption band located on the longest wavelength side of the absorption spectrum of the phosphorescent compound.
US09175211B2 Phosphorescent materials
Compounds comprising a 2-phenylpyridine ligand further substituted with a heterocyclic group are provided. In particular, the compound comprises a 2-phenylpyridine ligand further substituted with a nitrogen-containing heterocycle. The compounds may be used in organic light emitting devices to provide devices having improved efficiency and lifetime.
US09175210B2 Proppant particles formed from slurry droplets and method of use
Proppant material for hydraulic fracturing is provided. The particles of the proppant are formed by drip casting. A slurry of finely divided ceramic particles is flowed through nozzles and formed into droplets under the influence of vibration. Uniform sized, smooth surface, spherical green particles are formed. The green particles are dried and sintered to form the proppant. The proppant is used in the process of hydraulic fracturing of wells.
US09175209B1 Thermoset nanocomposite particles, processing for thier production, and their use in oil and natural gas drilling applications
Use of two different methods, either each by itself or in combination, to enhance the stiffness, strength, maximum possible use temperature, and environmental resistance of thermoset polymer particles is disclosed. One method is the application of post-polymerization process steps (and especially heat treatment) to advance the curing reaction and to thus obtain a more densely crosslinked polymer network. The other method is the incorporation of nanofillers, resulting in a heterogeneous “nanocomposite” morphology. Nanofiller incorporation and post-polymerization heat treatment can also be combined to obtain the benefits of both methods simultaneously. The present invention relates to the development of thermoset nanocomposite particles. Optional further improvement of the heat resistance and environmental resistance of said particles via post-polymerization heat treatment; processes for the manufacture of said particles; and use of said particles in the construction, drilling, completion and/or fracture stimulation of oil and natural gas wells are described.
US09175208B2 Compositions and methods for breaking hydraulic fracturing fluids
Breaking compositions are disclosed for controlled breaking of borate cross-linked fracturing fluids, and to method for making and using same, where the composition includes an oxidative component and an ester component.
US09175200B2 Azeotrope-like compositions comprising 1-chloro-3,3,3-trifluoropropene
An azeotrope-like mixture consisting essentially of chlorotrifluoropropene and at least one component selected from the group consisting of a C1-C3 alcohol, a C5-C6 hydrocarbon, a halogenated hydrocarbon, methylal, methyl acetone, water, nitromethane, and combinations thereof.
US09175198B2 Process for the preparation of a silicone pressure-sensitive adhesive
Silicone pressure sensitive adhesive (PSA) compositions and methods for their preparation are provided. In one embodiment, PSAs are formed from a silicone polymer mixture by condensation polymerization of low viscosity polyorganosiloxanes in inert solvents and/or silicone fluids, and optionally adding a silicone resin (MQ) during polymerization. The silicone polymer mixture formed may also be mixed with a silicone resin (MQ) and bodying catalyst, and bodying is allowed to continue until the desired reaction product is formed.
US09175197B2 Pressure-sensitive adhesive composition for optical films and pressure-sensitive adhesion type optical film
There is provided a pressure-sensitive adhesive composition for optical films, which is excellent in heat resistance, weathering resistance and bleed resistance, which has an excellent balance of pressure-sensitive adhesion properties, such as adhesive strength, cohesive force and tack, the tack of which can be controlled, which is excellent in initial reworkability when it is used for applying an optical film to an adherend or applying a protective film to an optical film, and which further exhibits excellent adhesive durability by virtue of rise of adhesive strength when such a film as above in the applied state is kept over a long period of time after application or especially when the film in the applied state is exposed to high temperatures or moist heat. A pressure-sensitive adhesive composition containing a specific acrylic diblock copolymer (I) and a specific acrylic triblock copolymer (II) in a specific proportion and a pressure-sensitive adhesive for optical films using the pressure-sensitive adhesive composition as a base are produced.
US09175196B2 Photocurable adhesive composition and display device comprising same
The present invention relates to a photocurable adhesive composition. The photocurable adhesive composition comprises a urethane(meth)acrylate resin, a functional-group-containing polybutadiene, a photocurable monomer and a photoinitiator; and the functional group is either an epoxy group or a hydroxyl group. The photocurable adhesive composition ensures good outdoor readability, has outstanding adhesive properties, and impact strength and optical transparency, and minimizes the phenomenon whereby substantial contraction occurs during photocuring, and thus can be suitably used for a display.
US09175194B2 Acrylic pressure-sensitive adhesive tape
An acrylic pressure-sensitive adhesive tape including an acrylic pressure-sensitive adhesive layer, wherein a 180° peel adhesive force of the acrylic pressure-sensitive adhesive tape to a glass plate is 10 N/20 mm or more and a 180° peel adhesive force of the acrylic pressure-sensitive adhesive tape to an acrylic plate is 10 N/20 mm or more. The acrylic pressure-sensitive adhesive layer contains an acrylic polymer (A), has a gel fraction of 65% or more, and has a 300% tensile residual stress of from 7 to 16 N/cm2.
US09175192B2 Method for manufacturing a label laminate
A method for manufacturing a label laminate. A transparent plastic film having a first side and a second side is introduced. The second side of the transparent plastic film is printed. A release liner including a release surface and single layer of a non-tacky adhesive on the release surface is introduced. The non-tacky adhesive on the release surface is activated so that the non-tacky adhesive becomes tacky. The tacky adhesive is attached on the release surface to the second side of the transparent plastic film.
US09175187B2 Self-etching cementitious substrate coating composition
Coating compositions for cementitious substrates may be made from a multistage latex polymer; silane; and a water-soluble acid, acid anhydride or acid salt capable of etching or otherwise reacting with the surface of the substrate to provide improved coating adhesion. The silane may be present as a silane coupling agent distinct from the multistage latex polymer, or may be present as silane functionality on the multistage latex polymer. The coating compositions adhere well to cementitious substrates and have a self-etching capability which improves coating adhesion, especially near edges and corners.
US09175186B2 Coating compositions having chelant functionality
The present invention provides an aqueous opaque coating formulation comprising (A) and aqueous solvent; (B) an inorganic material; and (C) a chelating polymer which comprises units derived from one or more aminocarboxylate compounds or their salts, one or more other polymerizable monomers, one or more ethylenically unsaturated monomers and, optionally, one or more crosslinking monomers. For example, the aminocarboxylate compounds or their salts may be one or more of iminodiacetic acid (IDA), iminodisuccinic acid (IDS), ethylenediamine triacetic acid (ED3A) and ethylenediamine disuccinic acid (EDDS), or their salts. Suitable polymerizable monomers may be one or more of glycidyl methacrylate (GMA), allyl glycidyl ether (AGE), vinylbenzyl chloride (VBC), allyl bromide, and their derivatives. The inorganic material may be a pigment, such as titanium dioxide (TiO2) or cadmium sulfide (CdS), or an extender or filler, such as talc (Mg3Si4O10(OH)2), calcium carbonate (CaCO3) or mica, or even combinations thereof.
US09175185B2 Coating compositions having high weathering resistance, process for preparation thereof and use thereof
What are described are coating compositions comprising pigments and/or fillers and multistage polyvinyl ester dispersions as binders. These binders are produced by a selected multistage process in which a polyvinyl ester dispersion is obtained in a first stage, monomers in dissolved or pure form or in the form of an emulsion are added to the reaction mixture in a second stage and then the polymerization is started again. The polyvinyl ester dispersions comprise polymerized silanes and/or epoxides or the polyvinyl ester dispersions have only a small content of protective colloids, if any. The coating compositions formulated with the multistage polyvinyl ester dispersions obtained in this way are notable for a very high weathering resistance.
US09175183B2 Transparent conductive films, methods, and articles
Disclosed are compositions and methods that provide flexible transparent conductive films that exhibit low levels of oligomer migration and haze development, without making use of costly substrates based on PEN film or PET films having low oligomer content. Such flexible transparent conductive films are useful in electronic and optical applications.
US09175181B2 Thermal inkjet latex inks
In one example, an anti-fouling latex ink includes a liquid vehicle, a pigment dispersed in the liquid vehicle, latex dispersed in the liquid vehicle, and a polystyrene anti-fouling additive dispersed in the liquid vehicle as a free solution. An illustrative method of formulating a latex inkjet ink includes forming a liquid vehicle with water as primary solvent, dispersing pigments in the liquid vehicle, and adding 0.01 wt % to 1 wt % of a polystyrene antifouling additive as a free solution to the liquid vehicle.
US09175179B2 Printing ink and coating compositions containing derivatives of starch and modified starch
A printing ink or coating composition contains optionally colorant and one or more derivatives of starches or modified starches.
US09175177B2 Coating composition
There is provided a polyester coating composition having excellent action of preventing deposition of outdoor stain and stain caused by rainfall, being capable of extending a period of time (pot life) from the mixing to the coating, and comprising (A) a polyester resin, (B) one or more of fluorine-containing organosilicon compounds having a fluorine content of 5 to 30% by mass, (C) one or more of aliphatic hydrocarbon compounds having hydroxyl group and 1 to 10 carbon atoms, in which a part of hydrogen atoms bonded to carbon atom may be substituted by fluorine atoms and/or one or more of alkoxy compounds having 2 to 10 carbon atoms, in which a part of hydrogen atoms bonded to carbon atom may be substituted by fluorine atoms, and (D) an organic solvent.
US09175174B2 Dispersions of submicron doped silicon particles
Methods are described that have the capability of producing submicron/nanoscale particles, in some embodiments dispersible, at high production rates. In some embodiments, the methods result in the production of particles with an average diameter less than about 75 nanometers that are produced at a rate of at least about 35 grams per hour. In other embodiments, the particles are highly uniform. These methods can be used to form particle collections and/or powder coatings. Powder coatings and corresponding methods are described based on the deposition of highly uniform submicron/nanoscale particles.
US09175171B2 Methacrylate resins for producing road markings
The invention relates to methacrylate resins and to their use.
US09175170B2 Method for coating metallic surfaces with a composition that is rich in polymers
The invention relates to a method for coating a metallic surface with an aqueous composition for pretreating before applying another coating or for treating said metallic surface. In addition to water, the composition contains: a) at least one hydrolyzable or at least partially hydrolyzed silane; b) at least one metal chelate; c) at least one organic film former, and; d) at least one long-chain alcohol that serves as a film forming aid. The unsoiled, scoured, cleaned and/or pretreated metallic surface is brought into contact with the aqueous composition so that a film forms on the metallic surface, which is subsequently dried, compacted in part or completely by film formation and, if necessary, additionally hardened. The dried and, if necessary, additionally hardened film has a layer thickness ranging from 0.01 to 10 μm. The invention also relates to corresponding aqueous compositions.
US09175169B2 Thermally sprayed completely amorphic oxide coating
The present invention relates to a process of producing an oxide coating, wherein an oxide or oxide composite composition is manufactured, then heated and, finally, sprayed onto a substrate by a thermal spraying process into a completely amorphous coating. The invention also relates to such a completely amorphous coating and to a substrate equipped with such a coating.
US09175164B2 Process for producing polymer alloy, polymer alloy, and molded article
A process of producing a polymer alloy includes melt-kneading at least two incompatible crystalline resins in a supercooled state by chaotic mixing using a twin-screw extruder. A polymer alloy obtained by melt-kneading at least two incompatible crystalline resins has a dispersed structure that particles dispersed in the polymer alloy have an average particle size of 0.001 to 1 μm, wherein in scattering measurement, (a) a peak half-width in a spectrum obtained by plotting scattering intensity against the wavenumber of scattered light and (b) a maximum wavenumber of the peak satisfy: 0<(a)/(b)≦1.5.
US09175162B2 Methods for forming stent coatings comprising hydrophilic additives
A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating system.
US09175160B2 Blend of poly(phenylene ether) particles and polyoxymethylene, article thereof, and method of preparation
A composition contains (a) 1 to 40 weight percent of poly(phenylene ether) particles having a mean particle size of 1 to 40 micrometers; and (b) 60 to 99 weight percent of a polyoxymethylene; wherein polystyrene is absent from the poly(phenylene ether) particles; wherein the composition comprises less than 0.1 volume percent, based on the total volume of the composition, of particulate metals, metalloids, oxides thereof, and combinations thereof, wherein the metals and metalloids are selected from iron, copper, aluminum, magnesium, lead, zinc, tin, chromium, nickel, tungsten, silicon, gold, silver, platinum, and alloys thereof. The poly(phenylene ether) particles reduce the density and increase the char yield of the polyoxymethylene. When the composition is prepared at a temperature below the glass transition temperature of the poly(phenylene ether), increased flexural strength can also be obtained. The composition is useful as a molding composition for a variety of articles.
US09175159B2 Thermoplastic elastomer composition
A thermoplastic elastomer composition containing a (meth)acrylic elastomer (component A), a thermoplastic resin having a melting point of from 180° to 350° C., and having a functional group reactive with an epoxy group (component B), and a vinyl copolymer having a solubility in tetrahydrofuran and having two or more epoxy groups in one molecule, on average (component C), wherein proportions of each of the components are: 40 to 95 parts by weight of the (meth)acrylic elastomer (component A), 5 to 60 parts by weight of the thermoplastic resin (component B), and 0.1 to 30 parts by weight of the vinyl copolymer (component C), a total of the (meth)acrylic elastomer (component A) and the thermoplastic resin (component B) being 100 parts by weight, wherein the component C is constituted by monomer units containing 50% by weight or more of monomer units (monomer unit c1) of which SP value is from 17.5 to 25.0, and wherein a flow beginning temperature is from 180° to 350° C. The molded article obtainable from the thermoplastic elastomer composition of the present invention can be used in various kinds of fields such as electric and electronic parts, automotive parts, sealants, packing, vibration proofed materials, and tubes.
US09175158B2 Resin composition
There is disclosed a resin composition from which a molded article excellent in scratch resistance and mechanical properties, low in gloss and low in shrinkage anisotropy can be obtained. Specifically, disclosed is a resin composition comprising 40% by weight to 90% by weight of a propylene polymeric material (A) containing 50% by weight or more of structural units derived from propylene, 9% by weight to 30% by weight of wollastonite (B), and 1% by weight to 30% by weight of an elastomer (C) where the combined amount of (A), (B) and (C) is taken as 100% by weight, wherein the wollastonite (B) satisfies specific requirements.
US09175156B2 Sustainable thermoplastic compounds
A thermoplastic compound is formed using a blend that includes one of processed fly ash, cinders and processed fly ash and cinders with a fractional melt having a melt flow index of less than 1 or a low melt resin with a melt flow index between 1 and about 3 or both, and a resin compatible with the fractional melt or low melt resin and having a melt flow index that is different from the melt flow index of the fractional melt or the low melt resin. Presence of the processed fly ash and cinders is believed to reduce cycle time for forming the thermoplastic compound into a plastic product from about 5 percent to about 30 percent merely because of the presence of the processed fly ash and cinders. Presence of the processed fly ash and/or cinders also permits the increased use of more fractional melt than conventionally attempted and also allows for use of thermoplastic regrind from recycling sources.
US09175155B2 Methods of functionalizing reclaimed elastomer material and compositions comprising the same
A method of functionalizing reclaimed elastomer material is described. The method involves subjecting particles of the reclaimed elastomer material to shear at temperatures less than 100° C. such that inter-chain bonds of the reclaimed elastomer material are cleaved wherein the particles of the reclaimed elastomer material have a size of 60 mesh or smaller. The reclaimed elastomer material can be subjected to shear in the presence of a modifier which selectively promotes the cleavage of inter-chain bonds in the reclaimed elastomer material. A functionalized reclaimed elastomer material made by a method as described above and an elastomer compound which comprises the functionalized reclaimed elastomer material are also described.
US09175148B2 C11 to C13 dialkyl esters of furandicarboxylic acid as softeners
The invention relates to C11 to C13 dialkyl esters of furandicarboxylic acid.
US09175144B2 Method for preparing a masterbatch of natural rubber and silica
The invention relates to a method for preparing a silica/natural rubber masterbatch, comprising the following successive steps: doping the silica with an at least divalent metallic element; preparing at least one dispersion of the resulting doped silica in water; bringing a natural rubber field latex into contact with the aqueous doped-silica dispersion and mixing them together so as to obtain a coagulum; recovering the coagulum; and drying the recovered coagulum so as to obtain the masterbatch.
US09175143B2 Method for producing particulate water-absorbent resin
A production of a water-absorbent resin by which a particle diameter of the water-absorbent resin can be controlled simply and conveniently, and a content of fine powder can be decreased, without necessity of change of raw materials or expensive facility investment is to be provided. The method is a continuous production method of a polyacrylic acid (salt)-based water-absorbent resin, comprising a polymerization step of an aqueous solution containing acrylic acid (salt), a drying step of the resultant hydrogel-like polymer, a pulverization step of the dried substance, a classification step of the pulverized substance, and optionally a surface cross-linking step of the classified substance, wherein (a) the drying step and the pulverization step are connected via a storage step and a transportation step; and (b) a time of holding the dried substance from a time of completing the drying step to a time of starting the pulverization step is set at 3 minutes or longer.
US09175139B2 Alkoxy group-containing silicones with reactive functional groups of defined reactivity
Organopolysiloxanes having a greater degree of defined reactivity through epoxy, isocyanate, anhydride, amino, carboxy, and (meth)acrylate groups are prepared by cohydrolytic condensation of reactive group-containing precursors and other condensable precursors in amounts such that the reactive organopolysiloxanes product contains on average more than two reactive groups, less than 20% by weight of alkoxy groups, and a proportion of non-reactive optionally substituted hydrocarbon groups such that the ratio of non-reactive hydrocarbon groups to Si atoms is greater than 1.
US09175133B2 Polyester with excellent thermostability and manufacturing method therefor
A polyester has excellent thermostability with only a small reduction in intrinsic viscosity during melt molding. The polyester is obtained from a dicarboxylic acid, and/or an ester-forming derivative thereof, and an ethylene glycol, a catalyst selected from the group consisting of a titanium compound, aluminum compound and antimony compound, a phosphorous compound selected from the group consisting of phosphoric acid, trimethyl phosphate, ethyl diethylphosphonoacetate, 3,9-bis(2,6-di-t-butyl-4-methylphenoxy) -2,4,8, 10-tetraoxa-3,9-diphosphaspiro[5,5]undecane and tetrakis(2,4-di-t-butyl-5-methylphenyl) [1,1-biphenyl]-4,4′-diylbisphosphonite, wherein the polyester contains 15 to 203 ppm of a sum of copolymerized 1,2-propanediol and/or uncopolymerized 1,2-propanediol wherein ethylene glycol is obtained from biomass and has content of 1,2-propanediol of 45 to 1000 ppm.
US09175130B2 Biostable polyurethanes
The present invention relates to a biostable polyurethane or polyurea comprising: (a) a soft segment comprising a polysiloxane of the general formula (I); and (b) greater than O and less than 40 wt % of a hard segment which is a reaction product of a diisocyanate and a linear difunctional chain extender, processes for their preparation and their use in the manufacture of biomaterials, devices, articles or implants.
US09175127B2 Method for producing an aliphatic polyester having increased molecular weight
The present invention relates to a method for producing an aliphatic polyester having an increased molecular weight comprising the steps of: (i) introducing into a mixing tank equipped with an inlet for injecting a diisocyanate an aliphatic polyester prepolymer which has a number average molecular weight of 5000 or higher and has terminal hydroxyl groups and in which at least one acid component is a succinic acid compound, wherein the aliphatic polyester prepolymer is introduced above the position of the inlet and wherein the aliphatic polyester prepolymer is melted at a temperature not lower than a melting point of the prepolymer and is in a liquid state, (ii) injecting a diisocyanate into the aliphatic polyester prepolymer, wherein the amount of diisocyanate is equivalent to between one tenth and two times the amount of the hydroxyl groups in the aliphatic polyester prepolymer; and (iii) reacting the aliphatic polyester prepolymer with the diisocyanate.
US09175126B2 Hydrophilic polyisocyanates
The invention relates to water-soluble or water-dispersible, hydrophilic polyisocyanates and polyisocyanate mixtures, to a process for preparing them, and to their use as a starting component in the production of polyurethane polymers, more particularly as crosslinkers for water-soluble or water-dispersible film-forming binders, adhesives binders, or sealant binders or binder components with or without groups which are reactive towards isocyanate groups.
US09175125B2 Polyurethane thickeners
The present invention relates to a process for preparing polyurethanes, which comprise at least three hydrophilic sections, at least four hydrophobic sections, optionally allophanate segments and/or isocyanurate segments and which are prepared in the presence of alkali(ne earth) metal carboxylates. The process may comprise using at least one carboxylic acid salt of at least one metal selected from the group consisting of the alkali metals, the alkaline earth metals and mixtures thereof Furthermore, the present invention relates to the polyurethanes per se obtainable in this way, to the use thereof as thickeners for aqueous preparations, and to preparations comprising polyurethanes of this type.
US09175124B2 Elastomer mixture mainly comprising a diene elastomer coupled by an aminoalkoxysilane group, rubber composition including the same and methods for obtaining same
The present invention relates to an elastomer mixture resulting from the modification of a diene elastomer by a coupling agent that introduces, into the elastomer chain, an alkoxysilane group bearing a tertiary or secondary amine functional group. This mixture predominantly comprises the diene elastomer coupled by the alkoxysilane group bearing a tertiary or secondary amine functional group which is bonded to the diene elastomer through the silicon atom. The invention also relates to a reinforced rubber composition, in particular that can be used for the manufacture of tires, which comprises a reinforcing filler and an elastomer matrix comprising at least this elastomer mixture, and to its preparation process. This composition has improved hysteresis and mechanical properties in the vulcanized state, and also improved processing in the uncured state.
US09175117B2 Dual cure composite resins containing uretdione and unsaturated sites
The present invention provides a dual-cure composition containing multifunctional polyols, uretidiones, peroxide curable monomers containing unsaturation and crosslinking agents. The dual-cure composition may be used to form a high modulus material useful as the matrix in a prepreg material and in composites. The present invention also relates to methods for the production of the dual-cure composition, prepreg materials comprising the dual-cure composition and a fibrous support, and composites made from the prepreg material.
US09175116B2 Polymeric water repellent material
The present invention relates to a polymeric water repellent material including novel acrylamide polymer, which can be used in various field because it demonstrates controllable and excellent water repellency together with water adhesiveness. The polymeric water repellent material comprises an acrylamide polymer including at least one repeating unit.
US09175115B2 Fluoropolymer resin treatment employing heating and oxygen source to reduce discoloration
Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from said aqueous medium to obtain said fluoropolymer resin. The process comprises: heating the fluoropolymer resin to a temperature of about 160° C. to about 400° C.; and exposing the heated fluoropolymer resin to an oxygen source.
US09175110B2 Fluoropolymer resin treatment employing melt extrusion and exposure to oxygen source to reduce discoloration
Process for reducing thermally induced discoloration of melt-processible fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from said aqueous medium to obtain said fluoropolymer resin. The process comprises melt extruding said fluoropolymer resin to produce molten fluoropolymer resin; and exposing said molten fluoropolymer resin to an oxygen source during said melt extruding.
US09175108B2 Process for synthesis of ethylene polymers
The present invention relates to a non-cryogenic process for the large scale synthesis of disentangled ultra high molecular weight polyethylene (DUHMWPE) polymers. The process comprises of the following steps: a. mixing FI catalyst of formula I with a hydrocarbon solvent containing poly-methyl aluminoxane (P-MAO) co-catalyst in a vessel under stirring before polymerization or directly in the polymerization vessel at a temperature ranging between 25° C. and 29° C. under a dry Nitrogen atmosphere; and lower concentration of co-catalyst resulting in the associated benefits as described earlier in the claims and descriptions. b. pressurizing ethylene in the polymerization vessel and polymerizing ethylene in a solution or a suspension, continuously or batch wise, in one or more stages at a temperature is in the range of 30° C. to 50° C.
US09175106B2 Activating supports
Activating supports are prepared by (a) combining (i) fluorine-containing compounds having a reactive group and (ii) an organometallic compound, (b) contacting a porous mineral oxide support material with the mixture from step (a), (c) heating the functionalized support from step (b) under an inert gas and then under an atmosphere comprising oxygen, and (d) recovering the activating support. The fluorine-containing compounds may have the formula R(Fn)-X wherein R is hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl or substituted heterohydrocarbyl with up to 20 non-hydrogen atoms, n is 1-41, X is OH, SH or NR′2, R′ is hydrogen or hydrocarbyl. The activating supports are useful in combination with transition metal catalysts for polymerization of olefins, e.g., with metallocene complexes. Preparation of the activating supports is easier and more economic than prior methods and provides for supported polymerization catalyst systems having excellent activities. Polymers produced using the activating supports exhibit improved rheology properties.
US09175105B2 Copolymers
Copolymer of ethylene and an alpha-olefin, having a density>0.930 g/cm3,melt index (g/10 min)>4, molecular weight distribution (MWD)>3.0, and FNCT>250 hours. The copolymer is suitable for use in rotomolding applications. The copolymer possesses improved impact strength, improved permeation resistance and improved environmental stress crack resistance and may suitably be prepared by use of metallocene catalysts.
US09175100B2 Process for making a solid catalyst component for ethylene polymerization and copolymerization
The present invention relates to a process for preparing a solid catalyst component suitable for producing polyethylene and its copolymers, said process comprising the steps of: (a) contacting a dehydrated support having hydroxyl groups with a magnesium compound having the general formula MgR1R2; (b) contacting the product obtained in step (a) with modifying compounds (A), (B) and (C), wherein: (A) is at least one compound selected from the group consisting of carboxylic acid, carboxylic acid ester, ketone, acyl halide, aldehyde and alcohol; (B) is a compound having the general formula R11f(R12O)gSiXh, (C) is a compound having the general formula (R13O)4M, and (c) contacting the product obtained in step (b) with a titanium halide compound having the general formula TiX4, wherein Ti is a titanium atom and X is a halide atom. The invention also relates to a solid catalyst component obtainable by said process. The invention further relates to a process for producing polyethylene and its copolymers in the presence of the solid catalyst component and a co-catalyst.
US09175099B2 Living radical polymerization method using a phosphorus compound or nitrogen compound as a catalyst
A highly active and environment-friendly catalyst for use in a living radical polymerization is provided. A catalyst for use in a living radical polymerization method is provided. The catalyst comprises a central element, which is selected from nitrogen and phosphorus, and at least one halogen atom, which is bound to the central element. A monomer having a radical reactive unsaturated bond is subjected to a radical polymerization reaction in the presence of the catalyst, thereby it is possible to obtain a polymer having narrow molecular weight distribution. The present invention has the merits such as low toxicity of the catalyst, a small amount of the catalyst being required, high solubility of the catalyst in the polymerization media, mild reaction conditions, no coloration, no odor (unnecessary post-treatment of molded products). The method of the present invention is more environment-friendly and economical than other living radical polymerization methods.
US09175095B2 Light-activated chimeric opsins and methods of using the same
Provided herein are compositions comprising light-activated chimeric proteins expressed on plasma membranes and methods of using the same to selectively depolarize excitatory or inhibitory neurons.
US09175087B2 Humanized anti-CXCR5 antibodies, derivatives thereof and their use
The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders.
US09175086B2 CD20 antibodies and uses thereof
CD20 is a transmembrane protein of the tetra-spanin family expressed on the surface of B-cells from peripheral blood as well as lymphoid tissues. CD20 expression persists from the early pre-B cell stage until the plasma cell differentiation stage. In addition to expression in normal B-cells, CD20 is expressed in B-cell derived malignancies such as non-Hodgkin's lymphoma (NHL) and B-cell chronic lymphocytic leukemia (CLL). The present invention includes anti-CD20 antibodies and antigen-binding fragments thereof comprising a light chain variable region and a heavy chain variable region, wherein the CDR-L1, CDR-L2, and CDR-L3 of said light chain variable region comprise the amino acid sequences of SEQ ID NOs: 23-25, respectively, and wherein the CDR-H1, CDR-H2, and CDR-H3 of said heavy chain variable region comprise the amino acid sequences of SEQ ID NOs: 26-28, respectively.
US09175083B2 Antigen-binding polypeptides and their uses
Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
US09175081B2 Therapeutic use of anti-CS1 antibodies
The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.
US09175080B2 Antibody against human prostaglandin E2 receptor EP4
It is an object of the present invention to provide an antibody that binds to a human PGE2 receptor subtype EP4 and inhibits the function of EP4, or a functional fragment thereof. It is another object of the present invention to provide a medicament comprising the aforementioned antibody or a functional fragment thereof. Mice were immunized with the human PGE2 receptor subtype EP4, and a monoclonal antibody that suppresses the intracellular cAMP level increase induced by EP4 was screened. In addition, the CDR sequences of the obtained monoclonal antibody were determined.
US09175074B2 Pharmaceutical composition for treatment and/or prophylaxis of cancer
An object of the present invention is to prepare an antibody that targets CAPRIN-1 specifically expressed on the surface of cancer cells and is superior in antitumor activity to conventional antibodies and to provide use of the antibody as a therapeutic and/or preventive agent for cancer. The present invention provides use of an antibody targeting an identified cancer antigenic protein specifically expressed on the surface of cancer cells as a therapeutic and/or preventive agent for cancer, specifically, a pharmaceutical composition for treatment and/or prevention of cancer, comprising as an active ingredient an antibody or a fragment thereof which has immunological reactivity with a CAPRIN-1 protein, the antibody or the fragment thereof comprising a heavy chain variable region comprising amino acid sequences represented by SEQ ID NOs: 5, 6, and 7 and a light chain variable region comprising amino acid sequences represented by SEQ ID NOs: 9, 10, and 11.
US09175073B2 Methods for detecting Th1 cells
The inventors discovered that the adhesion molecule CAR, known to be localized in intracellular adhesion sites, functioned as an adhesion molecule for activated lymphocytes. Further, the inventors identified CARL, a novel CAR ligand expressed in lymphocytes, and clarified that the ligand was expressed selectively in Th1 cells. In addition, they found that anti-CAR antibodies could inhibit the adhesion of activated lymphocytes to CAR molecules. Thus, the present invention provides methods for detecting Th1 cells using CAR or anti-CARL antibodies, and methods of screening for inhibitors suppressing the adhesion of Th1 cells using the binding between CAR and CARL as an index. Furthermore, the present invention relates to methods of screening for inhibitors of the binding between CAR and CARL, antibodies that inhibit the binding between CAR and CARL, and therapeutic compositions comprising these antibodies. These are expected to be useful in diagnosing diseases, such as inflammation, in which infiltration of Th1 cells is involved, and in providing pharmaceutical agents for alleviating such diseases.
US09175067B2 Immunoglobulin G Fc region binding polypeptide
An immunoglobulin G Fc region binding polypeptide is provided, consisting of an amino acid sequence selected from i) a variant of Protein A domain or Protein Z and ii) an amino acid sequence which has at least 95% identity thereto. Also provided are methods for producing the polypeptide, compositions comprising the polypeptide, polynucleotides encoding the polypeptide, multimers of the polypeptide, and methods of using the polypeptide.
US09175064B2 HLA-E chimeric molecule
HLA-E chimeric molecules for providing nonhuman mammalian cells resistant to cytotoxic human NK cells, nucleotide sequences encoding these chimeric molecules, and nonhuman mammalian cells and nonhuman mammals transformed with such nucleotide sequences are disclosed herein. The HLA-E chimeric molecules of the invention contain a peptide that reforms all or part of the signal peptide region, α1 domain and/or α2 domain of HLA-E, and a nucleotide sequence of the invention encodes a HLA-E chimeric molecule. A transformant incorporating a nucleotide sequence of the invention expresses HLA-E efficiently.
US09175063B2 Anti-angiogenic agent and methods of using such agent
Anti-angiogenic agents or polypeptides comprising an amino acid segment substantially similar to domain one of CD2 wherein the polypeptide has a β-sheet formed by two segments. Methods of using such agents and polypeptide are also included.
US09175056B2 Bis-sulfhydryl macrocyclization systems
Peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production are described.
US09175052B2 Tobacco-derived protein compositions
The disclosure describes methods for the purification of protein-enriched extracts to provide concentrates and isolates and methods for incorporation of such materials into products. The purification methods are adapted for removal of one or more of ash, metal salts, alkaloids, particulates, heavy metals, and other impurities and/or contaminants from extracts, as well as modifying the sensory characteristics (e.g., odor, color, and/or taste characteristics) of extracts. The methods generally include diafiltration, treatment with functionalized resins, and supercritical extraction. A protein composition in the form of a concentrate or isolate is provided, the protein composition including RuBisCO, F2 fraction proteins, or combination thereof extracted from a plant of the Nicotiana species, wherein the protein composition is characterized by one or more of: an ash content of less than about 15% by weight; a nicotine content of less than about 10 μg/g; and a heavy metal content of less than about 60 μg/g.
US09175048B2 Use of peptides as transporters intended for the internalization of molecules of interest into target cells
The method pertains to a peptide including the amino acid sequence SEQ ID NO: 1, or a peptide including an amino acid sequence having 93%, in particular 95%, particularly 98% sequence identity homology with the sequence SEQ ID NO: 1, in order to obtain a transporter intended for the internalization of a molecule of diagnostic or therapeutic interest into the target cells.
US09175046B2 Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
Compositions and methods for the therapy and diagnosis of Inflammatory Bowel Disease (IBD), including Crohn's Disease and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more bacterial polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of IBD.
US09175042B2 Cyclosporin analogs
Disclosed herein are novel analogs of cyclosporin, pharmaceutical compositions containing them, and methods for their use in the treatment of dry eye and other conditions.
US09175041B2 Crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline, and methods for preparing dolamethylleuine and dolaphenvaline
The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon.
US09175037B2 Neuromedin U derivative
An object of the present invention is to provide a novel anorectic agent. Another object of the invention is to provide an NMU derivative which exhibits a high anorectic effect even when administered in a usual manner, for example, peripherally. These objects can be achieved by the compound represented by formula (I) or a salt thereof. In formula (I), Y represents a polypeptide containing an amino acid sequence set forth in SEQ ID NO.: 1 wherein 1 to 4 amino acids are substituted; X represents a methoxypolyethylene glycol; X′ is absent or represents a methoxypolyethylene glycol; and a moiety represented by formula: La-Lb-[Lc]j represents a linker.
US09175030B2 Derivatives of avicin D and methods of making and using thereof
Disclosed herein are novel oxetane derivatives of avicin D, including compounds of the formula (I), wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives and compositions thereof, including for the treatment of cancer, are also provided.
US09175026B2 Synthesis of thioether containing trialkoxysilanes
The invention relates to a radical-initiated thiol-ene or thiol-yne “click” reaction that provides a simple and efficient route to diverse trialkoxysilanes. Trialkoxysilanes made in this way are obtained in quantitative to near-quantitative yields with high purity without any or minimal purification. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. The modular nature of these radical-based thiol-ene or thiol-yne “click” reactions allows a wide variety of pendant groups to be coupled to silane compounds that can then be coupled to a wide variety surfaces in order to modify their material properties. Consequently, such radical initiated thiol-ene and thiol-yne reactions provide facile and efficient methods for preparing an enormous number of surface-active functional trialkoxysilanes.
US09175023B2 Molybdenum allyl complexes and use thereof in thin film deposition
Molybdenum complexes and use thereof in thin film deposition, such as CVD and ALD are provided herein. The molybdenum complexes correspond in structure to Formula (I) and Formula (II), wherein R1, R3, R5, R7, R8 and R10 are independently and at each occurrence alkyl; R2, R6 and R9 are independently alkyl; R4 and R11 are independently and at each occurrence selected from the group consisting of alkyl, alkenyl, and alkynyl; x, z, a, c, d and f are independently zero, 1, or 2; y, b and e are independently zero or 1; and n and m are independently zero to 5.
US09175019B2 Industrial process for the preparation of N-alkyl-N-trialkylsilylamides
The present invention relates to a process for producing N-alkyl-N-trialkylsilylamides from trialkylsilylhalides and N-alkylamides in the presence of a base and in the absence of a solvent.
US09175018B2 Boronate ester compounds and pharmaceutical compositions thereof
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
US09175017B2 Boronate ester compounds and pharmaceutical compositions thereof
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
US09175015B2 Gold nanoparticle conjugates and uses thereof
The disclosure generally relates to formation of polymers grafted to or polymerized from the surface of gold nanoparticles. The polymers are functionalized to include therapeutic agents and/or targeting agents at their surface, thereby allowing both therapeutic and targeting compounds to be directed to specific cells in a patient.
US09175014B2 Method for preparing Cu-BTC and nano-Cu-BTC
The methods for preparing Cu-BTC and nano-Cu-BTC are disclosed. An imporous coordination compound Cu(C9H4O6)(H2O)3 is impregnated an organic solvent or a steam environment thereof to obtain Cu-BTC. Cu-BTC is impregnated in an acidic protic solvent environment and filtered to obtain a solid, and the solid is impregnated in a non-acidic organic solvent or a steam environment thereof, centrifuged, washed, and dried, to obtain nano-Cu-BTC.
US09175012B2 Method for producing optically active diamine derivative
The problem to be solved is to provide an important intermediate for production of an FXa inhibitor. The solution thereto is a method for industrially producing a compound (1) or a compound (4), comprising: [Step 1]: adding a quaternary ammonium salt and a metal azide salt to water to prepare an aqueous solution of an azidification reagent complex comprising quaternary ammonium salt-metal azide salt, and subsequently dehydrating the aqueous solution using an aromatic hydrocarbon solvent to form a mixed solution of the azidification reagent complex comprising quaternary ammonium salt-metal azide salt and the aromatic hydrocarbon solvent with a water content of 0.2% or less; and [Step 2]: adding, to the mixed solution prepared in [Step 1], a compound (2) wherein L represents a leaving group.
US09175010B2 Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6H)-ones
Described herein are compounds of Formula I and Formula II, methods of their synthesis, compositions comprising the compounds, and use of the compounds and compositions in treating numerous diseases and disorders, including cognitive deficits associated with CNS diseases and disorders.
US09175006B2 Compositions and methods for cyclofructans as separation agents
The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.
US09175004B2 Catalyst precursor, method for producing the same, method for using the same, and reactor that uses the same
The present invention provides the catalyst precursor that has excellent safety and stability, has high stable activity retention rate, can be recycled, increases yield resulted from a reaction, and is easily processed into various forms. The catalyst precursor comprises a structure in which the entire structure is composed of gold or a gold-based alloy and the surface of the structure is modified with elemental sulfur, or at least the surface of the structure is composed of gold or a gold-based alloy and the surface of the structure is modified with elemental sulfur, and a catalytic metal compound supported on the structure, wherein the catalyst precursor has peaks derived from the catalytic metal compound and also sulfur as analyzed by photoelectron spectroscopy, and wherein the peak derived from sulfur is of the sulfur 1s orbital observed within a range of 2470 eV±2 eV in terms of the peak top position.
US09175001B2 [1,3] dioxolo [4,5-g] [1,2,4] triazolo [1,5-a] quinoline derivatives as inhibitors of the late SV40 factor (LSF) for use in treating cancer
The present invention relates generally to [1,3]dioxolo[4,5-g]quinoline-6(5H)thione and [1,3]dioxolo[4,5-g][1,2,4]triazolo[1,5-a]quinoline derivatives and/or compositions for use in inhibiting, preventing and/or treating cancer, e.g. hepatocellular carcionoma (HCC). In some embodiments, the invention relates to the use of small-molecule compounds to inhibit, prevent and/or treat expression of the transcription factor Late SV40 Factor (LSF) for treatment of HCC or other cancer types.
US09174997B2 4-(4-cyano-2-thioaryl)dihydropyrimidinones and use thereof
The present invention relates to novel 4-(4-cyano-2-thioaryl)dihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
US09174991B2 Crystalline form of pemetrexed disodium
The present invention relates to a new polymorphic or crystalline form of Pemetrexed Disodium, processes for its preparation and its use, in particular for the preparation of medicaments.
US09174990B2 2-amino-9-[(2-hydroxymethyl) cyclopropylidenemethyl] purines as antiviral agents
Compounds which are active against viruses have the following Formulas: wherein B is 2-aminopurine-9-yl, which may be unsubstituted or substituted in the 6 position with NHR1, OR2, or SR3; R1 is selected from the group consisting of alkyl, alkenyl, alkynyl, and C4-18 cycloalkyl, any of which may be optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl; R2 is selected from the group consisting of C2-18 alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl, and aryl; and R3 is selected from the group consisting of alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl.
US09174988B2 Small molecule inhibitors of hepatitis C virus
The invention provides derivatives and analogs of triazatetracyclo[7.7.0.01,13.02,7]-hexadeca-2,4,6,10,12-pentaenes, 5,7,11-triazatetracyclo[8.7.0.01,6.012,17]-heptadeca-6,8,12,14,16-pentaenes, pharmaceutical compositions comprising these compounds and methods for treatment of hepatitis C viral infections using these compounds.
US09174986B2 Tropomyosin-related kinase (Trk) inhibitors
Tropomyosin-related kinase inhibitors (Trk inhibitors) are small molecule compounds useful in the treatment of disease. Trk inhibitors can be used as pharmaceutical agents and in pharmaceutical compositions. Trk inhibitors are useful in the treatment of inflammatory diseases, autoimmune disease, defects of bone metabolism and/or cancer, and are particularly useful in the treatment of osteoarthritis (OA), pain, and pain associated with OA. Trk inhibitors are also useful for inhibiting tropomyosin-related kinase A (TrkA), tropomyosin-related kinase B (TrkB), tropomyosin-related kinase C (TrkC), and/or c-FMS (the cellular receptor for colony stimulating factor-1 (CSF-1)).
US09174982B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
US09174981B2 Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as type III receptor tyrosine kinase inhibitors
Compounds of Formula I: and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal.
US09174980B2 Heterocyclic compounds as inhibitors of leukotriene production
The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R7, A and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
US09174978B2 Monobactam organic compounds for the treatment of bacterial infections
This invention pertains generally to antibacterial compounds of Formula I, as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negative bacteria.
US09174976B2 Cyanoisoquinoline compounds and methods of use thereof
The present invention relates to cyanoisoquinoline compounds suitable for use in treating hypoxia inducible factor-mediated and/or erythropoietin-associated conditions. The cyanoisoquinoline compounds of the invention have the following structure:
US09174971B2 Process for the preparation of compounds useful as inhibitors of SGLT2
The present invention is directed to a novel process for the preparation of compounds having inhibitory activity against sodium-dependent glucose transporter (SGLT) being present in the intestine or kidney.
US09174969B2 Indoline scaffold SHP-2 inhibitors and cancer treatment method
The subject invention concerns methods and compounds for inhibiting Shp2. In one embodiment, a compound of the invention has a chemical structure as shown in formula I or II: wherein X, Y, and Z are independently N or S; R1 is cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, any of which can be optionally substituted with one or more of halogen; alkyl; heteroalkyl; —COOH; —C(R3)3, wherein R3 can independently be any of —H or halogen; or —OR4, wherein R4 can be any of H, alkyl, or heteroalkyl; R2 is alkyl, alkylcarbonyl, heteroalkylcarbonyl, aryl, arylcarbonyl, heterocycloalkylcarbonyl, cycloalkylcarbonyl, or —C(O)NR6R7, any of which can be optionally substituted with one or more of halogen; alkyl; heteroalkyl; carbonyl; —OR4, wherein R4 can be —H, alkyl, or heteroalkyl; —OH; —C(R3)3, wherein R3 can independently be any of —H or halogen; aryl, which can be substituted with one or more of halogen or —OR4; heterocycloalkyl; or —C(O)OR5, wherein R5 can be —H or alkyl; R6 and R7 are independently —H, alkyl, heteroalkyl, aryl, or heteroaryl; and R′ is H or alkyl; or a pharmaceutically acceptable salt or hydrate thereof.
US09174966B2 Crystalline forms of 6-(1H-imidazol-1-yl)-2-phenylquinazoline
The present invention relates to the solid state of 6-(1H-imidazol-1-yl)-2-phenylquinazoline (I) and therefore to novel crystalline forms of the base and of pharmaceutically acceptable salts and solvates thereof, and also to methods for preparing them, to the respective pharmaceutical formulations and to their therapeutic use. Compound (I) may be obtained as the free base in five different crystalline forms, three polymorphic forms and two hydrates. Some pharmaceutically acceptable salts of (I) that have physicochemical characteristics acceptable for pharmaceutical development were obtained, and the respective polymorphic forms and/or hydrates were characterized.
US09174962B2 Processes for the preparation of pesticidal compounds
The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
US09174956B2 Process for preparation of 3-((2S,5S)-4-methylene-5-(3-oxopropyl)tetrahydrofuran-2-yl)propanol derivatives and intermediates useful thereof
Discloses is a process for preparation of a compound of formula 7, or a derivative thereof, wherein PG1 is an alcohol protecting group. Also, disclosed are intermediates and processes for their preparation. The compound of formula 7 can be useful in the preparation of halinchondrin analogs such as Eribulin.
US09174953B2 Bicyclic thiazoles as allosteric modulators of mGluR5 receptors
The present invention relates to novel bicyclic thiazoles which are positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (“mGluR5”) and which are useful for the treatment or prevention of disorders associated with glutamate dysfunction and diseases in which the mGluR5 subtype of receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which mGluR5 is involved.
US09174946B2 Selective FAK inhibitors
A compound of the formula (I): where R1 or R2 is a cycle, amine group and R5 is an aromatic group with a carbonyl containing substituent for use as a FAK inhibitor.
US09174944B1 Crystalline lopinavir/surfactant adducts
This invention relates to novel crystalline lopinavir/surfactant adducts, methods for their preparation, therapeutic uses of those crystalline lopinavir/surfactant adducts, and pharmaceutical compositions containing them or made from them.
US09174943B2 Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds
Processes are provided for the synthesis of diarylthiohydantoin and diarylhydantoin compounds. Medicinal products containing the same find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.
US09174939B2 Soft rock inhibitors
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease.In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and Respiratory diseases.
US09174938B2 Organic electroluminescence device
An organic electroluminescence device including: an anode (10), a cathode (70), an emitting layer (40) including an organic compound, which is between the anode (10) and the cathode (70), two or more layers arranged in a hole injection and transport region which is between the anode (10) and the emitting layer (40), and one or more layers arranged in an electron injection and transport region which is between the emitting layer (40) and the cathode (70), wherein a layer in the hole injection and transport region, which is in contact with the emitting layer (40), includes an aromatic amine derivative having a carbazole skeleton, one of the layers other than the layer in contact with the emitting layer (40) in the hole injection and transport region includes one or more materials selected from the group consisting of thiophene derivatives, tricyclic or more cyclic fused aromatic derivatives, amine derivatives excluding the compound represented by the following formula (A), conductive polymers, CFx, CuPc, transition metal oxides, fullerenes and acceptor materials, and a layer in the electron injection and transport region includes a benzimidazole derivative.
US09174936B2 Retinal derivatives and methods for the use thereof for the treatment of visual disorders
Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
US09174933B2 Polymorphic form of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and uses thereof
Disclosed herein, in certain embodiments, is a crystalline polymorph form A of N—(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide. Further disclosed herein, in certain embodiments, are pharmaceutical compositions comprising the crystalline polymorph form A of N—(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide.
US09174928B2 Process for improving the selectivity of an EO catalyst
Processes for the epoxidation of ethylene are provided in which, following start-up, an epoxidation catalyst is contacted with a feed comprising ethylene, oxygen, carbon dioxide in an amount below 2.0 vol. %, and a chloride moderator to achieve a desired work rate at a first operating temperature T1. The composition of the feed is subsequently adjusted (e.g., by decreasing the ethylene concentration, decreasing the oxygen concentration, increasing the carbon dioxide concentration and/or adjusting the concentration of the chloride moderator) so as to increase the first operating temperature T1 to a second operating temperature T2 while maintaining the desired work rate. As the catalyst activity declines, the composition of the feed is further adjusted so as to maintain the desired work rate at the second operating temperature T2.
US09174924B2 Hydrolysable linkers and cross-linkers for absorbable polymers
The present invention relates to the discovery of new class of linear and multiarmed hydrolysable linkers and cross linkers for use in the synthesis of biodegradable polymers such as, polyesters, polyurethanes, polyamides, polyureas and degradable epoxy amine resin. The linear and multiarmed hydrolysable linkers of the present invention include symmetrical and/or unsymmetrical ether carboxylic acids, amines, amide diols, amine polyols and isocyanates.
US09174923B2 Alkyl lactyllactate solvent compositions
Alkyl lactyllactate and alkoxylated alkyl lactyllactate compounds that are useful as solvents in a variety of applications are disclosed. The compounds are derived from a hydroxyl containing compound and a lactide or lactic acid source that has a specific chirality. The alkyl lactyllactate and alkoxylated alkyl lactyllactate compounds are particularly suitable for use as solvents in applications requiring cold tolerance performance without inclusion of additional volatile components.
US09174922B2 Method for producing vinyl esters
The present invention relates to a continuous, catalytic process for preparing a vinyl ester of the formula R—C(O)O—CH═CH2 by reaction of a carboxylic acid of the formula R—C(O)OH with a transvinylating reagent of the formula R1—C(O)O—CH═CH2, wherein the reaction is effected at a temperature of 90 to 160° C. and at a pressure of 0.5 to 15 MPa without withdrawal of a reactant in the presence of a transition metal catalyst containing at least one transition metal from the group of ruthenium, osmium, rhodium, iridium, palladium and platinum, and then the resulting reaction mixture is separated into its constituents.
US09174920B1 Integrated process of distillation with side reactors for synthesis of organic acid esters
An integrated process and system for synthesis of organic-acid esters is provided. The method of synthesizing combines reaction and distillation where an organic acid and alcohol composition are passed through a distillation chamber having a plurality of zones. Side reactors are used for drawing off portions of the composition and then recycling them to the distillation column for further purification. Water is removed from a pre-reactor prior to insertion into the distillation column. An integrated heat integration system is contained within the distillation column for further purification and optimizing efficiency in the obtaining of the final product.
US09174918B2 Process for preparing diaryl oxalate
Disclosed is a process for preparing a diaryl oxalate which comprises the step of transesterifying a dialkyl oxalate or/and an alkylaryl oxalate with an aryl alcohol in the presence of a tetra(aryloxy)titanium as a catalyst, wherein the tetra(aryloxy)titanium is fed into a reaction system of the transesterification as an aryl alcohol solution of the tetra(aryloxy)titanium which is prepared by reacting a tetraalkoxy titanium and an excess amount of the aryl alcohol and removing a by-producing alkyl alcohol.
US09174904B1 Synthesis of 2,2-bis(3-phenyl-4-hydroxyphenyl) propane (PHP)
Disclosed herein are ortho aryl substituted bisphenol monomers that exhibit a lower binding energy to estradiol related receptors. The monomers are provided by the condensation of a ketone and phenol in the presence of an acid catalyst.
US09174903B2 Reactive scrubbing for upgrading product value, simplifying process operation and product handling
A method for removing formaldehyde from a blend of partially oxygenated hydrocarbons is provided. The method including a step of reacting a hydrocarbon-containing gas with an oxygen-containing gas in a reaction vessel to form first product blend. The first product blend includes a blend of partially oxygenated compounds that include formaldehyde. The blend of partially oxygenated compounds is provided to a reactive scrubbing station where it is contacted with a reactive scrubbing liquid to form a reactive liquid-formaldehyde compound. The reactive liquid-formaldehyde compound is then removed from the first blend of partially reactive compounds.
US09174901B2 Temporary desulphurization reactor for pre-treating a hydrocarbon feed before steam reforming with a view to hydrogen production
The present invention describes a process for pre-treating a steam reforming feed containing sulphur-containing compounds, using two desulphurization reactors: a temporary desulphurization reactor (1010) containing an active adsorbent solid; a permanent desulphurization reactor (1003) placed upstream of the steam reforming unit, which contains an adsorbent solid in the passivated state, necessitating a depassivation phase in order to be rendered active; the temporary desulphurization reactor (1010) being disconnected as soon as the adsorbent solid of the permanent desulphurization reactor (1003) has been activated, and the volume of the temporary desulphurization reactor being in the range 1/20 to 1/200 times the volume of the permanent desulphurization reactor.
US09174900B2 Method for production of CO, H2 and methanol-synthesis gas from a synthesis gas, in particular from acetylene off-gas
The invention relates to a method for production of a methanol-synthesis gas product stream (2), an H2 product stream (3) and a CO product stream (4) from an H2- and CO-containing synthesis gas stream (5).
US09174899B2 Method for producing optically active alcohols
A method is provided for producing optically active alcohols from ketones by reducing a ketone in the presence of an iridium(III) complex having a chiral prolinamide compound as a ligand. The ketone is preferably a compound represented by formula [I]: (wherein R1 and R2 are different from each other, and each represent an optionally substituted straight or branched alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, an optionally substituted heteroaryl group, an optionally substituted aralkyl group, an optionally substituted heteroarylalkyl group, an optionally substituted alkenyl group or an optionally substituted alkynyl group, and R1 and R2 may be bound to each other at any appropriate position to form a ring, the ring optionally containing one or more atoms which may be the same or different and are selected from an oxygen atom, an optionally substituted nitrogen atom and a sulfur atom, and optionally being condensed with an aromatic or hetero-aromatic ring).
US09174895B2 Methods of regenerating aromatization catalysts
Methods for treating or rejuvenating a spent catalyst are disclosed. Such methods can employ a step of halogenating the spent catalyst, followed by decoking the halogenated spent catalyst. The halogenation step can utilize fluorine and chlorine together, or fluorine and chlorine can be applied sequentially.
US09174894B2 Method for producing cycloolefin and production apparatus thereof
There is provided a method for producing cycloolefin where the nickel which elutes in the liquid-contact portion of the reactor is removed from the reaction system of the partial hydrogenation reaction and cycloolefin can be stably produced from a monocyclic aromatic hydrocarbon over a long term. A method for producing a cycloolefin by a partial hydrogenation reaction of a monocyclic aromatic hydrocarbon in an aqueous phase, which contains a metal salt-containing acidic aqueous solution and a ruthenium catalyst in a reactor with a liquid-contact portion formed of a nickel-containing material, the method comprising a first step of bringing at least a part of the ruthenium catalyst contained in the aqueous phase into contact with oxygen, a second step of separating the aqueous phase containing the ruthenium catalyst that has been processed in the first step into a first phase containing the ruthenium catalyst at a high ratio and a second phase containing the ruthenium catalyst at a lower ratio than the first phase, and a third step of feeding the first phase to a reaction system of a partial hydrogenation reaction.
US09174892B2 Process for increasing a mole ratio of methyl to phenyl
One exemplary embodiment can be a process for increasing a mole ratio of methyl to phenyl of one or more aromatic compounds in a feed. The process can include reacting an effective amount of one or more aromatic compounds and an effective amount of one or more aromatic methylating agents to form a product having a mole ratio of methyl to phenyl of at least about 0.1:1 greater than the feed.
US09174889B2 Metal hydride nanoparticles
A nanoparticle of a decomposition product of a transition metal aluminum hydride compound, a transition metal borohydride compound, or a transition metal gallium hydride compound. A process of: reacting a transition metal salt with an aluminum hydride compound, a borohydride compound, or a gallium hydride compound to produce one or more of the nanoparticles. The reaction occurs in solution while being sonicated at a temperature at which the metal hydride compound decomposes. A process of: reacting a nanoparticle with a compound containing at least two hydroxyl groups to form a coating having multi-dentate metal-alkoxides.
US09174886B2 Coated particles, methods of making the same, and methods of use
Embodiments of the present disclosure provide for coated particles, compositions including coated particles, methods for making coated particles, methods of reducing dust, and the like.
US09174884B1 Closed loop compost tea brewer
A closed loop compost tea brewing system with a hydroponic reservoir and a compost tea brewing assembly configured to brew compost tea. The compost tea brewer assembly includes a tea brewing reservoir. The system includes has a closed loop arrangement fluidly connecting the tea brewing reservoir and the hydroponic reservoir. The closed loop arrangement is configured to provide continuous fluid flow from the tea brewing reservoir to the hydroponic reservoir, which is recirculated back from the hydroponic reservoir to the tea brewing reservoir.
US09174882B2 Method for converting oil-based drilling fluids, fracking fluids, and produced waters into fertile indigenous top soil
A waste fluid is evaluated to determine if the waste fluid includes fracturing fluid requiring treatment for sodium; a hydrocarbon level requiring hydrocarbon treatment; and/or drilling fluid requiring clay treatment. The waste fluid is mixed with mature compost, organic fertilizer, and top from the well site. If the waste fluid requires treatment for sodium, calcium nitrate is mixed with the waste fluid in an amount sufficient to balance the sodium content thereof. If the waste fluid includes a hydrocarbon level requiring hydrocarbon treatment, an additional organic fertilizer is mixed with the waste fluid along with hydrocarbon-digesting microbes in an amount sufficient to inoculate the waste fluid. If the waste fluid includes drilling fluid requiring clay treatment, the waste fluid is mixed with gypsum to break up and reduce adhesive characteristics of clay particles present in the waste fluid. The mixture is stirred and dried to produce fertile top soil.
US09174879B2 Ceramic precursor batch composition and method of increasing ceramic precursor batch extrusion rate
A ceramic precursor batch composition comprising inorganic ceramic-forming ingredients, a hydrophobically modified cellulose ether binder having a molecular weight less than or equal to about 300,000 g/mole and an aqueous solvent is provided. The ceramic precursor batch composition has a ratio of binder to aqueous solvent of less than about 0.32. The ceramic precursor batch composition may be used to increase the rate of extrusion of the composition. A method for increasing a rate of extrusion of a ceramic precursor batch composition is also disclosed.
US09174877B2 Colored translucent zirconia sintered body, its production process and its use
A colored translucent zirconia sintered body contains a transition metal element as a coloring agent, having a clear color tone and high transparency, and being excellent in both design properties and esthetic properties, and its production process. A colored translucent zirconia sintered body includes yttria in an amount of at least 6 mol % and at most 15 mol % and at least one member selected from the group consisting of iron, nickel, manganese, cobalt, chromium, copper and vanadium in an amount of at least 0.02 mol % and at most 0.5 mol % as calculated as oxides, and having a porosity of at most 1,000 ppm. The average crystal grain size is preferably at most 60 μm.
US09174873B2 Material to be used as a concrete additive
The invention relates to an admixture for a cementitious composition comprising microfibrillar cellulose and/or a derivative thereof. The invention also relates to a method of manufacturing said admixture and to the use of the microfibrillar cellulose and/or a derivative thereof in the concrete admixture. The invention further relates to a cementitious composition comprising said admixture and methods of manufacture and use thereof.
US09174867B2 Glass plate and process for its production
A cover glass includes a soda lime silica glass including SiO2, MgO, CaO, Na2O and Al2O3. The SiO2 content in the silica glass is in the range of 60 wt % to 71.1 wt %, the MgO content in the silica glass in the range of 4.5 wt % to 15 wt %, the CaO content in the silica glass in the range of 0.5 wt % to 10 wt %, the Na2O content in the silica glass in the range of 10-20 wt %, the Al2O3 content in the silica glass in the range of 0-10.3 wt %, the silica glass has the ratio [MgO]/[CaO] of larger than 1 and the Q value of 20 or larger, and the Q value is obtained by formula, Q =([MgO]/[CaO])X([CaO]+[Na2O]−[Al2O3]), where [MgO] is the MgO content, [CaO] is the CaO content, [Na2O] is the Na2O content, and [Al2O3] is the Al2O3 content by mass percentage based on oxides.
US09174863B2 Leach field system
A wastewater system is provided. The system includes channels and conduits for wastewater guidance and discharge. High aspect ratio channels and one or more distribution conduits are provided in the system such that wastewater, such as septic wastewater, is discharged from the system and into the system surroundings. The high aspect ratio channels are spaced apart from each other to allow for the discharge of the wastewater effluent from the system between the channels. The channels have a high height to width aspect ratio.
US09174862B1 Membrane bioreactor with reduced air scour requirements
In a sewage treatment plant with a membrane bioreactor (MBR), raw untreated or partially treated wastewater (influent) and/or mixed liquor in the intensified process is superoxygenated. In a preferred form of the process the influent is superoxygenated such that membrane air scouring requirements are reduced. Influent may be fed to a swing zone where denitrification and nitrification occur simultaneously through process control. In one embodiment superoxygenation is conducted in an internal recycle stream of the mixed liquor, with oxygen content supersaturated preferably to over 300 parts per million. Due to the active evolution of oxygen gas from the supersaturated stream, occurring preferably by seeding the supersaturated stream with air bubbles, the supersaturated oxygen can serve the dual purposes of meeting process oxygen demands and providing part of air scouring requirements for the membranes.
US09174855B2 Tributyl phosphate-nitrate solvent extraction process for producing high purity nuclear grade rare earth metal oxides
An improved process for the preparation of high purity rare metal compounds such as oxides utilizing TBP (Tri-Butyl Phosphate)-nitrate solvent extraction technique adapted to manufacture nuclear grade rare metal compounds such as zirconium oxide wherein the said process substantially aids in reducing the specific generation of ammonium nitrate effluent volume thereby increasing its concentration when the said effluent comprising ammonium nitrate and ammonium sulphate are utilized for stripping of the said rare metal compound from the organic solvent in the said process of production of high purity rare metal oxide powder.
US09174851B2 Compositions containing polyhydroxyoxoaluminum cations and manufacture thereof
A composition comprising a polyhydroxyoxoaluminum cation detectable at 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the composition.
US09174850B2 Gaseous ammonia removal method
A system and method for passive capture of ammonia in an enclosure containing material that gives off ammonia. The invention allows for the passage of gaseous NH3 through microporous hydrophobic gas-permeable membranes and its capture in a circulated acidic solution with concomitant production of a concentrated non-volatile ammonium salt.
US09174847B2 Synthesis of high quality carbon single-walled nanotubes
Methods and processes for synthesizing high quality carbon single-walled nanotubes (SWNTs) are provided. A carbon precursor gas at reduced concentration (pressure) is contacted with a catalyst deposited on a support and at temperature about 10° C. above the SWNT synthesis onset temperature, but below the thermal decomposition temperature of the carbon precursor gas for given growth conditions. The concentration (pressure) of the carbon precursor gas can be controlled by reducing the total pressure of the gas, or by diluting with an inert carrier gas, or both. The methods produce SWNTs with the ratio of G-band to D-band in Raman spectra (IG:ID) of about 5 to about 200.
US09174846B2 Ferric phosphate and methods of preparation thereof
High-purity crystalline ferric phosphate material with desirable characteristics for use in synthesis of nano-sized LFP cathode material are described. The ferric phosphate dihydrate material has as disclosed herein has a molar ratio of phosphorous to iron is from about 1.001 to about 1.05, a surface area of from about 25 m2/g to about 65 m2/g, and is substantially free of metallic or magnetic impurities. Methods of synthesizing high-purity crystalline ferric phosphate material with desirable characteristics for use in synthesis of nano-sized LFP cathode material are also described. In some embodiments, one or more magnetic traps are used during the reaction process and/or after the formation of the final product to remove magnetic impurities. In some embodiments, a synthetic method of ferric phosphate using multiple steps is described, wherein the intermediate of the synthesis is isolated and purified to improve the purity of the ferric phosphate material. In some embodiments, an iron compound is added to an aqueous solution of phosphoric acid. The solution pH and temperature are controlled to ensure the complete dissolution of the iron compound. The desired iron phosphate crystalline material can be obtained with high purity and high crystalline phase purity by controlling the pH and temperature of the solution.
US09174844B2 Calcium looping process for high purity hydrogen production integrated with capture of carbon dioxide, sulfur and halides
A process for producing hydrogen comprising the steps of: (i) gasifying a fuel into a raw synthesis gas comprising CO, hydrogen, steam, sulfur and halide contaminants in the form of H2S, COS, and HX, wherein X is a halide; (ii) passing the raw synthesis gas through a water gas shift reactor (WGSR) into which CaO and steam are injected, the CaO reacting with the shifted gas to remove CO2, sulfur and halides in a solid-phase calcium-containing product comprising CaCO3, CaS and CaX2; (iii) separating the solid-phase calcium-containing product from an enriched gaseous hydrogen product; and (iv) regenerating the CaO by calcining the solid-phase calcium-containing product at a condition selected from the group consisting of: in the presence of steam, in the presence of CO2, in the presence of synthesis gas, in the presence of H2 and O2, under partial vacuum, and combinations thereof.
US09174835B2 Microstructure and electronic device
A method of manufacturing microstructures, such as MEMS or NEMS devices, including forming a protective layer on a surface of a moveable component of the microstructure. For example, a silicide layer may be formed on one or more surfaces of a poly-silicon mass that is moveable with respect to a substrate of the microstructure. The process may be self-aligning.
US09174825B2 Elevator
A car for an elevator, which is movable in an elevator shaft, has a car roof projecting at least partly beyond a drive unit. Arranged on the car roof in the region of the side facing the drive unit is a balustrade which has a handrail interrupted centrally in a drive receiving region. The balustrade has in the drive receiving region a bar which is arranged to be offset downwardly and inwardly relative to the handrail.
US09174824B2 Elevator system having remote call registration request
An elevator system includes a group control device controlling a plurality of elevators as a group, a security gate mounted with a personal identification device that identifies a passing user and issues identification information, an access control device that issues validation information based on the information about the user included in the identification information, a communication device transmitting a service floor call registration request for each user to the group control device based on the validation information, an assignment controlling function that is provided on the group control device to determine the elevator assigned pursuant to the service floor call registration request for each user, and issue assigned elevator information for each user, and an assigned elevator notification device installed on the security gate to notify each user of the assigned elevator information.
US09174821B2 Sheet folding device having sheet retaining mechanism
A sheet folding device includes a first folding unit, a retreat path, a sheet retaining mechanism, and a second folding unit. The first folding unit forms a first fold in a sheet. The retreat path is entered by the sheet having the first fold formed by the first folding unit, and has a stop portion to be contacted by the first fold. The sheet retaining mechanism moves a movable member with respect to the sheet that enters the retreat path, and regulates movement of the sheet in the retreat path in a direction of thickness of the sheet. The second folding unit forms a second fold in the sheet having the first fold while allowing the sheet that has contacted the stop portion to exit the retreat path.
US09174816B2 Sheet aligning and shifting device
A sheet storage apparatus includes a sheet discharge path having a sheet discharge outlet; a stack tray disposed on a downstream side of the sheet discharge outlet; a support device disposed between the sheet discharge outlet and the stack tray to load at least a part of a sheet; a sheet end regulation device for regulating a position of at least one end edge of the sheet supported by the support device; and an aligning transport device disposed in the support device to carry the sheet toward the sheet end regulation device. The aligning transport device includes a friction transport body and a transport body travel device, and the friction transport body has a rotating member rolling along the top surface of the sheet supported by the support device, and the rotating member rotates in a direction crossing the travel direction.
US09174813B2 Image forming apparatus
An image forming apparatus includes: a sheet feed section including a plurality of sheet feed cassettes, a designation receiving section configured to receive a designation of a sheet feed cassette for exclusive use from among the plurality of sheet feed cassettes; an exclusive use control section configured to put the sheet feed cassette the designation of which has been received by the designation receiving section into an exclusive use state and, when a predetermined condition is satisfied, switch the sheet feed cassette from the exclusive use state to a non-exclusive use state; and a sheet discharge control section. When the predetermined condition is satisfied, the sheet discharge control section allows the discharge of particular paper sheets remaining in the sheet feed cassette in the exclusive use state before the sheet feed cassette is switched from the exclusive use state to a non-exclusive use state.
US09174810B1 Waste bag use methods and apparatus
In a method for using a dumpster bag, the bag comprises: a flexible bag member including a bottom and a sidewall structure extending upward from the bottom to a rim; and a plurality of loops. The method comprises: engaging a hoist to a group of the loops; using the hoist to lift the bag containing contents; releasing the hoist from one or more of the loops; and using the hoist to again lift the bag to discharge the contents from the bag.
US09174805B2 Conveyor apparatus for loading and unloading an aircraft
A conveyor apparatus for loading and unloading aircraft, the apparatus comprising a first conveyor for conveying articles from an area outside of an aircraft to an entrance to a cargo compartment of the aircraft, and a second conveyor for conveying articles from an end of the first conveyor into the cargo compartment, the second conveyor being telescopically extendable from the first conveyor, wherein the second conveyor comprises an endless flexible member extending between a tail end of the second conveyor adjacent the first conveyor and a head end of the second conveyor segment at a distal end of the second conveyor, and a driver for driving the endless member to convey articles along the second conveyor.
US09174800B1 Verifying bin content in a materials handling facility
This disclosure describes a device and system for verifying the content of items in a bin within a materials handling facility. In some implementations, a bin content verification apparatus may pass by one or more bins and capture images of those bins. The images may be processed to determine whether the content included in the bins has changed since the last time images of the bins were captured. A determination may also be made as to whether a change to the bin content was expected and, if so, if the determined change corresponds with the expected change.
US09174793B2 Rigid cartridge for coffee and soluble products for preparing beverages
A cartridge (1) for coffee or soluble products for producing a beverage, includes a container (2) able to contain the coffee or soluble product, a lid (6) disposed over the container so as to define a top wall for entry into the container of the hot water under pressure for formation of the beverage, a filter (4) able to be positioned inside the container above a bottom wall (20) of the container through which the beverage flows out, wherein the bottom wall of the container has a weakened, less thick central area (22), suitable to be broken by mechanical elements or by the pressure of the liquid inside the cartridge to allow delivery of the beverage, there being provided a plurality of concentric, spiral-shaped channels, ending in the less thick central area, able to cause a swirling movement of the beverage, with the consequent formation of a dense froth.
US09174791B2 Temperature-stabilized storage systems
Systems include at least one substantially thermally sealed storage container, including an outer assembly including one or more sections of ultra efficient insulation material substantially defining at least one thermally sealed storage region, and an inner assembly including one or more interlocks configured to provide controllable egress of a quantity of a material from one or more of the at least one thermally sealed storage region.
US09174786B2 Valve assembly
A valve assembly (2) intended for use together with a pallet container (1) and a liner. The valve assembly (2) comprises a valve (3), a valve seal (4) and an outer lip seal (5). The valve assembly (2) further comprises a support member (6) which is constitutes of a lower guide member (61) and an upper guide member (62).
US09174783B1 Reusable gift wrap
A reusable gift wrap assembly includes two discrete sleeves that are together configured to conceal exterior surfaces of a gift box upon covering the gift box with the sleeves. Each sleeve includes two material layers that are connected together along a portion of their perimeter so as to define an interior pocket and an open end through which the gift box is inserted. One of the sleeves includes a free open end that is positioned to at least partially overlap a free open end of other sleeve so as to conceal the free open end of the other sleeve when the sleeves are assembled onto a gift box. Each sleeve is formed from a resilient fabric material such that the sleeves can conform to gift boxes of varying shape and size.
US09174782B2 Flexible multi-panel sterilization assembly
A multi-panel sterilization assembly includes a barrier panel formed of a permeable material, a fold protection panel, and at least one panel attachment means. The barrier panel has a first end, an opposed second end, and a midpoint delineating the barrier panel into a content receiving region and a content covering region. Panel attachment means are located at or near edges of the barrier panel to identify the content receiving region. The fold protection panel has a proximal end and an opposed distal end. After the barrier panel is folded at or near the midpoint to bring its second end near its first end and its edges are brought together and secured by the panel attachment means to form a package, the fold protection panel folds at or near a pre-determined fold line to cover at least a portion of the edges of the folded barrier panel.
US09174781B2 Tie wrap for bundling objects
A holder includes a body, the body having a first and second receiver and a first and second cylindrical holder. The holder further includes a tie that is an elongated piece of shape-retaining deformable material and a cover covering the shape-retaining deformable material along the length of the elongated piece. The covering and the shape-retaining deformable material are bonded along their length. A first portion of the tie passes through the first cylindrical holder. A second portion of the tie passes through the second cylindrical holder, such that a loop is formed between the body and the tie, stretching from the first cylindrical holder to the second cylindrical holder.
US09174779B2 Vial cap 187
An elastomeric vial cap used for sealing a vial container, but allowing pipette access to its containment fluid includes an annular flange portion for capping the vial and a sloped truncated cone portion to easily guide the pipette into the vial container. A tubular seal portion is configured to encircle the truncated cone portion and firmly engage an inside wall of the vial container with ease of insertion. A center flap portion is circumscribed by a channel at its top surface for penetration by the pipette and has a flex portion. The center flap portion separates around the perimeter of the channel but hinges at the channel above the flex portion and does not become dislodged. The ratio of the diameters of the pipette and the center flap portion is such that significant problems related to back-pressure and vacuum conditions do not exist during transfer of the containment fluid.
US09174777B2 Liquid receiving bottle with drop by drop dispensing head
The invention relates to a bottle for packaging a liquid with dropper delivery comprising a reservoir with an elastically deformable wall that can be reversed by letting air into the receptacle, surmounted by a dispensing head for the liquid comprising a drop-counting end-piece protruding to the outside of the bottle and an anti-bacterial filtering membrane, made partially hydrophilic and partially hydrophobic, which is interposed across the path of the liquid and of the air, at the base of the said end-piece. The dispensing head comprises an insert with a recessed body which contains a porous pad regulating the flow of liquid placed downstream of the reservoir and upstream of a chamber delimited downstream of the said membrane. At the base of this insert on the inner side of the bottle, longitudinal arches supporting a central pellet make star-shaped passageways radially guiding the air that enters the bottle after having passed through the porous pad.
US09174775B2 Actuator-driven dispenser
Dispenser and methods of dispensing substances is provided. The dispenser comprises a housing having a longitudinal axis, the housing configured to receive a packet comprising at least one collapsible cavity containing at least one substance, a support member positioned in the housing, the support member having a longitudinal axis essentially parallel to the longitudinal axis of the housing, a wedge coupled to the support member, the wedge configured to move in a plane substantially parallel within the longitudinal axis of the housing, the wedge receiving a force directed substantially normal to the longitudinal axis of the housing, and a reciprocating actuator coupled to the housing and engagable with the support member, the actuator moveable between a first position and a second position whereby the wedge advances a single predetermined increment collapsing a portion of the cavity.
US09174774B2 Containers for cooking foodstuffs
The present invention is concerned with flexible cooking containers which the user can fill with selected foodstuff and then seal same prior to inserting in the microwave oven for preferably cooking the contents at greater than atmospheric pressure for improved health/hygiene reasons and for improved taste and flavor. The user can thus select the nature of the foodstuffs which are to be cooked.
US09174773B2 Closure clip having a plurality of spikes
A closure clip is provided for closing tubular or bag-shaped packaging for bulk produce such as fruit or vegetables. The closure clip includes a first arm and a second arm extending substantially in a plane and aligned at least approximately parallel to each other, with the arms each having first and second ends and a base portion extending in the center plane defined by the arms and having an inner and an outer surface, with the base portion connecting the first and second arms at their first ends and forming an approximately U-shaped closure clip. The closure clip further includes a first spike having a first end and a second end, extending from the inner surface of the base portion between the arms and parallel thereto, and connected with its first end to the base portion. The closure clip further has at least one second spike having first and second ends.
US09174767B2 Shipping pallet with fork pass-through protection
A pallet includes a support structure configured to accept fork tines, a deck secured to the support structure, and a plate secured to at least one of the deck and the support structure by a securing device. The securing device is configured to allow movement of the plate between a first position obstructing entry of a fork tine through the support structure and a second position allowing entry of a fork tine through the support structure. The securing device is configured to allow movement of the plate from the first position to the second position when a fork tine impacts the plate from a first direction. The plate is blocked from moving from the first position when a fork tine impacts the plate from a second direction opposing the first direction.
US09174763B2 Carton with insert
A carton for holding a plurality of containers. The carton comprises a plurality of panels that extends at least partially around an interior of the carton. At least two end flaps can cooperate to at least partially form a closed end of the carton. A reinforcing insert comprises a central panel and at least one reinforcing end flap. The central panel can be at least partially disposed in the interior of the carton, and the at least one reinforcing end flap can comprise a base portion and a distal portion foldably connected to the base portion. The base portion extends in an oblique direction from the central panel toward the closed end of the carton.
US09174759B2 Blow molded plastic container having improved top load strength
A blow molded plastic container includes a main body portion having an upper surface and a finish portion that extends from the upper surface. A reinforcing strut is provided on the upper surface of the main body portion adjacent to the finish portion for providing increased structural rigidity and top load strength to the container. The reinforcing strut may be fabricated in a manner that promotes drainage of fluid from the container, such as by defining a downwardly sloping inner channel that leads to the finish portion when the container is inverted.
US09174748B2 Rail system and method and system for mounting a component in an aircraft
A rail system for use when assembling a component in an aircraft comprises a first rail element having a securing device which is designed to be complementary to a first securing device provided in the region of a floor of an aircraft fuselage element and is adapted to cooperate with the first securing device in order to releasably secure the first rail element in the region of the floor of the aircraft fuselage element, wherein a section of the first rail element projects beyond an edge of the floor of the aircraft fuselage element in the connected state of the first rail element and the aircraft fuselage element. The first rail element furthermore comprises a guide device, which is designed to be complementary to a first guide device provided on an assembly aid, which is to be introduced into the aircraft fuselage element, and is adapted to cooperate with the first guide device to enable a guided displacement of the assembly aid to be introduced into the aircraft fuselage element relative to the rail system. The rail system furthermore comprises a second rail element having a securing device which is designed to be complementary to a second securing device provided in the region of the floor of the aircraft fuselage element and is adapted to cooperate with the second securing device in order to releasably secure the second rail element in the region of the floor of the aircraft fuselage element, wherein a section of the second rail element projects beyond an edge of the floor of the aircraft fuselage element in the connected state of the second rail element and the aircraft fuselage element. The second rail element furthermore comprises a guide device, which is designed to be complementary to a second guide device provided on an assembly aid, which is to be introduced into the aircraft fuselage element, and is adapted to cooperate with the second guide device to enable a guided displacement of the assembly aid to be introduced into the aircraft fuselage element relative to the rail system.
US09174743B2 Protective cover for aircraft pitot probes
A protective cover for a pilot probe of an aircraft comprising a first tubular member formed of a rigid material, and a second tubular member formed of a rigid material, and a second tubular member formed of a flexible material including a first ply disposed on an inner side of the first tubular member, having an opening at a first end thereof for receiving the leading end of a pilot probe therein and a closed second end, and a second ply disposed on an outer side of the first tubular member, having a first end thereof secured about the first end of the inner ply and a second end secured to the second end of the first ply.
US09174742B2 Assistance with piloting of an aircraft in a stall
An intuitive display including a visual representation of a maximum admissible angle of attack on a pitch scale giving the crew of an aircraft a visual recognition of an imminent stall, or of a stall, together with real assistance with piloting during the stall until the aircraft has come out of the stall completely.
US09174740B2 System for supplying an aircraft with inert gas, method for supplying an aircraft with inert gas, use of a membrane and aircraft
A system for supplying an aircraft with inert gas is provided. The system includes at least one fuel cell with an air inlet and an exhaust air outlet as well as a membrane device with an inlet, an outlet and a vapor-permeable membrane. The exhaust air outlet is in fluid communication with the inlet of the membrane device. The membrane device guides a gas from the inlet to the outlet and to give off to the outside through the membrane any water vapor contained therein. This leads to a cost efficient, passive and reliable dehumidifaction of inert exhaust gas for inerting purposes, and a dehumidification device that does not or only marginally increases the weight of the aircraft.
US09174739B2 Active vibration control system
An active vibration control system includes a plurality of actuators corresponding to and disposed adjacent each engine of an aircraft, at least one sensor located within a passenger cabin of the aircraft and configured to detect a magnitude and frequency of one or more of vibration and sound produced by a respective engine and generate one or more of a vibration and sound feedback signal, and a controller connected to each of the plurality of actuators and each of the at least one sensor, the controller being configured to effect control of no more than two of the plurality of actuators for a respective engine based the feedback signal where the no more than two actuators effect suppression of one or more of vibration and sound of a respective engine due to rotating axis of the respective engine.
US09174736B2 Air passenger seat having a frame
Proposed is an air passenger seat having a frame which is provided for attaching to a floor of an aircraft cabin and a backrest which is pivotably or securely mounted on the frame by means of a rotation spindle, wherein the seat has a seat reference point (SRP) which is defined according to the SAE International Aerospace Standard AS8049. According to the invention, the rotation spindle of the backrest has, in a line parallel to the cabin floor and as seen parallel to the direction of flight, a separation n of less than 40 mm from the seat reference point.
US09174735B2 Sealing device for galley hard point
A sealing device for mounting a monument on a structural element of an aircraft and for providing a seal between the sealing device and the floor of the aircraft is provided. The sealing device comprises a cylindrical element with a pin for attaching the sealing device to the structural element and a recess for receiving another pin of a mounting device to which the monument is attached. The sealing device may have a smaller diameter than a mounting block of the mounting device such that the seal cannot be damaged by trolley wheels.
US09174731B2 Fixed engine and rotating proprotor arrangement for a tiltrotor aircraft
A tiltrotor aircraft includes a fuselage; a wing member having a first rib, a second rib, a first spar, second spar; and an upper wing skin; an engine disposed at a fixed location relative to the wing member; and a proprotor having a spindle gearbox, rotor mast, and a plurality of rotor blades drivable in rotation about the rotor mast, the spindle gearbox being rotatable about a conversion axis. The spindle gearbox is located above the upper wing skin of the wing member.
US09174727B2 Landing gear steering using eccentric bearings
A landing gear assembly for an aircraft, the landing gear assembly including: an elongate bogie beam; a first axle bearing having an outer part rotatably coupled to an inner part, the outer part being coupled to the bogie beam, the inner part including a mounting aperture; and an elongate axle provided through the mounting aperture of the inner part and coupled thereto, wherein the axle is coupled to the inner part of the first axle bearing in a configuration such that the longitudinal axis of the axle is spaced from the axis of rotation of the inner part, such that rotation of the inner part causes a change in the orientation of the axle relative to the bogie beam.
US09174726B2 Driving device for wheel of airplane
A driving device for driving a wheel of an airplane in a direction same as that of a revolution of the wheel after landing, includes a revolution drive disc having a flat ring plate having an attachment portion adapted to attach on a side surface of a tire of the wheel; and a plurality of fins arranged on the ring plate. The plurality of fins is obliquely arranged on an outer side surface of the ring plate so that when the plurality of fins receives relative atmospheric air flow, a torque generated by the fins at a lower side of the tire in the direction same as that of the revolution of the wheel after landing is larger than a torque generated by the fins at an upper side of the tire in a direction reverse to that of the revolution of the wheel after landing.
US09174725B2 Systems for tasks guidance of operations management in an aircraft cockpit
Aircraft guidance assistance systems and computer readable media are disclosed. The present subject matter includes systems and computer readable media for providing task guidance for managing flight operations during normal operating procedures or exceptional situations caused by abnormal events. In some aspects, a system for providing task guidance can include a processor, memory, and a flight assistance module configured to receive data from multiple servers. The assistance module can display possible aircraft flight phases while indicating the flight phase. The assistance module can also display operations to be carried out for the flight phases, and the actions corresponding to these operations.
US09174723B2 Shape memory alloy rods for actuation of continuous surfaces
A system for connecting two relatively movable structures on an aircraft, comprising: a first rigid structure attached to one of the relatively movable rigid structures; a second rigid structure attached to another of the relatively movable structures; a flexible skin connected to the first and second rigid structures; a sleeve comprising first and second end portions; a first rod comprising a first end portion attached to the first rigid structure, a second end portion slidably coupled to the first end portion of the sleeve, and an intermediate portion made of shape memory alloy; a second rod comprising a first end portion attached to the second rigid structure, a second end portion slidably coupled to the second end portion of the sleeve, and an intermediate portion made of shape memory alloy; and means for heating at least the intermediate portions of the first and second rods.
US09174722B2 Aircraft interior panel with acoustic materials
A panel assembly that includes a first panel having an inner surface and an outer surface, and a second panel having an inner surface and an outer surface. The second panel includes a plurality of rib members formed therein that extend inwardly. The rib members include an inner surface and an outer surface. A plurality of panel portions are defined between the plurality of rib members. The panel portions include an inner surface and an outer surface. The inner surface of the rib members are secured to the inner surface of the first panel, and the inner surface of the panel portions is spaced apart from the inner surface of the first panel to define at least first and second cavities.
US09174719B1 Tendon routing at envelope apex
A top cap assembly is provided for mounting tendon to a balloon that has a balloon envelope. The assembly includes a plate structure having a plurality of junction portions disposed at an apex of the balloon envelope and a plurality of tendon pairs. Each tendon pair includes first and second tendon members attached to the balloon envelope. The first tendon member is arranged to cross over the plate structure. The second tendon member is arranged to engage the first length tendon member at a given one of the junction portions of the doubler plate. A fastener member is attached to each tendon pair of the plurality of tendon pairs. The fastener member is used for securing the first and second tendon members of a given tendon pair together in order to support lift gas carried by the balloon envelope.
US09174717B2 Intake air cooling system for a marine vessel having a turbocharger
Provided is an intake air cooling system for a marine vessel having a turbocharger. The intake air cooling system for the marine vessel includes: a turbocharger which compresses the intake air introduced from the outside using a portion of the exhaust gas generated by the engine, wherein the turbocharger has a front end through which the intake air is introduced and a rear end through which the compressed intake air is supplied to the engine; a cooling part which cools at least one of the intake air compressed in the turbocharger and the exhaust gas passing through the turbocharger, wherein the cooling part includes one or more cooling units disposed along the flow of the intake air or the exhaust gas; and an absorption cooling device which receives heat from the working fluid circulated through the cooling unit.
US09174716B2 Exhaust structure of outboard motor
Exhaust gas from an engine passes through a lower unit, and passes through a propeller boss coupled to a propeller shaft to be discharged into water. An outside diameter of a front end portion of the propeller boss is set to be equal to or larger than an outside diameter of a rear end portion of a gear case in the lower unit.
US09174713B2 Unmanned underwater vehicle
An unmanned underwater vehicle (UUV) is disclosed. The UUV includes a body and a propulsion system for propelling and orienting the UUV. The propulsion system has an inlet formed in the body that facilitates fluid being drawn into the UUV from outside the body. The propulsion system also has a duct in fluid communication with the inlet. The duct is adapted to direct the fluid along a flow path. The propulsion system further includes a pump operable with the duct to increase the velocity of the fluid. In addition, the propulsion system includes a nozzle in fluid communication with the duct to receive the fluid at the increased velocity. The nozzle is supported about a side of the body and adapted to moveably redirect fluid out of the UUV. The propulsion system provides multi-axis control of the UUV.
US09174711B2 Device and system for manoeuvring cleaning apparatuses
Device for maneuvering and propulsion of a cleaning apparatus for removal of marine fouling from marine installations below surface. The device at least includes an induction part adapted to supply a fluid at high pressure, a nozzle with an inlet for supply of the fluid at high pressure, and a tubular body with an induction side and an outlet where said nozzle is arranged close to the induction side. The device also includes a system for cleaning of marine installations where one or more devices for maneuvering and propulsion are used.
US09174710B2 Vessel, motion platform, method for compensating motions of a vessel and use of a Stewart platform
A method for compensating for motion of a boat as it floats on water includes measuring the motion of the boat relative to another element in an area surrounding the boat, generating a driving signal for driving actuators operatively associated between the boat and at least one carrier based on motion of the boat, driving the actuators to hold the at least one carrier substantially stationary relative to the element based on the driving signal and relieving weight on the actuators by at least partially bearing the weight of a load and the at least one carrier by an at least partially passive pressure element.
US09174707B2 Ship for transporting a liquefied natural gas storage container
An LNG storage container carrier includes: one or more cargo holds provided on a hull such that upper portions thereof are opened; a plurality of first and second upper supports installed on the cargo holds in a width direction and a length direction to partition the upper portions of the cargo holds into a plurality of openings, wherein storage containers are vertically inserted into the openings and supported; and a lower support installed under the cargo holds and supporting the bottoms of the storage containers inserted into the openings. Accordingly, it is possible to efficiently and stably transport the storage containers storing LNG or PLNG pressurized at a predetermined pressure. Such storage containers may be transported through simple modification of the existing container carrier.
US09174705B2 Compensated lashing of tender assist drilling unit to a floating production facility
A system of lashing a tender assist drilling unit (TADU) to a floating production platform includes a plurality of lashing lines reeved over a hydraulic-pneumatic tensioning system sheave assembly and a plurality of fixed anchor points to the above water line section of the production platform hull structure. The hydraulic-pneumatic tensioning device will, when in tensioning mode, compensate and control the relative movement between the two floating bodies. The hydraulic-pneumatic tensioning system will also enable lashing pre-tension adjustments during operations and fine-tuning of system performance can be done site-specific based on lessons learned. The hydraulic-pneumatic tensioning device will, when in hydraulic lock mode, enable a fixed lashing line system. This will by the means of the first units mooring winch system enable; a winch-in for close proximity during heavy lifting; or an efficient lashing pay put during extreme weather preparation for increased separation between the two units.
US09174703B2 Wake-modifying device for a boat
A recreational sport boat includes a hull, having starboard and port sides and a transom, and a pair of wake-modifying devices positioned aft of the transom. One of the wake-modifying devices is positioned on a port side of the boat's centerline and another of the wake-modifying devices is positioned on a starboard side of the boat's centerline. Each wake-modifying device includes a plate-like member and at least one downturned surface at a trailing portion of the plate-like member. Each wake-modifying device is pivotable between a non-deployed position and a deployed position about a pivot axis that is horizontal or inclined no more than about 35° from horizontal. When a wake-modifying device is in the deployed position, the downturned surface is lower than it is in the non-deployed position so as to be able to modify the boat's wake.
US09174696B2 Grip for handlebars of a bicycle and similar vehicle and method therefore
A grip includes a substantially tubular body equipped with ends and having a substantially cylindrical cavity with a longitudinal axis (X), the body being able to be fitted on an end of the handlebars, a padding associated with the body, a cover positioned above the padding, means for fastening the grip to the handlebars, the cover including a thermoshrinking and/or thermoformable material, so that, following a heating and/or cooling, the cover takes the form of the padding.
US09174695B1 Head parts assembly for a bicycle with a cable collecting device
A head parts assembly for a bicycle with a cable collecting device includes two bowl assemblies disposed at two ends of a front vertical pipe to collect brake cables, each of the bowl assemblies includes a bowl, a bearing disposed between the bowl and the front vertical pipe, and a cover for fixing the bearing inside the bowl. The bowl includes an assembling portion and an engaging portion tapering from the assembling portion, the engaging portion engages with the front frame pipe, the assembling portion is an annular structure and defines an opening, an annular rib is formed on an inner surface of the assembling portion, and the bearing is restricted in the opening. The assembling portion has plural penetrating holes penetrating the inner surface and an outer surface of the assembling portion, and the brake cables are inserted into the front frame pipe via the penetrating holes.
US09174692B2 Foldable mobility device
A foldable mobility device includes a chassis assembly, a steering assembly rotatably coupled to the chassis assembly, a seat assembly coupled to the chassis assembly through a first folding mechanism configured to convert the seat assembly between a first folded position and a first unfolded position, a front wheel assembly coupled to the steering assembly and configured to be rotated by the steering assembly for steering the foldable mobility device, and one or more rear wheel assemblies coupled to the chassis assembly through a second folding mechanism configured to convert the one or more rear wheel assemblies between a second folded position and a second unfolded position.
US09174690B2 Wiring structure to supply power to license light of two-wheeled vehicle
A wiring structure to supply power to a license light provided in a two-wheeled vehicle includes a wire, a connector, a vehicle-body-side harness, and a plug. The wire is connected to the license light attached to a fender support. The fender support is attached to a back surface of a rear fender which is detachably attached to a vehicle body. The connector is attached to a leading end of the wire and to the fender support. The vehicle-body-side harness is fastened to a vehicle-body frame with a fastener at a position lower than an attachment position of the connector. The vehicle-body-side harness extends upward toward the connector. The plug is provided to the vehicle-body-side harness and is connected to the connector to supply power from the vehicle body to the license light.
US09174689B2 Vehicle headlight and projection lens
A vehicle headlight can form a predetermined high-beam light distribution pattern, while being capable of causing the chromaticity of the entire light distribution pattern to fall within a white range (JIS D5500). The vehicle headlight can include: a projection lens that can control light incident on its light incident surface at a first incident position near its optical axis to be directed in a direction not parallel to the optical axis, can control light incident at a second incident position away from the optical axis to be directed in a direction parallel to the optical axis, and can control light incident at an incident position between the first and second incident positions to be directed in a direction closer to the direction parallel to the optical axis as the light is incident at an incident position closer from the first incident position to the second incident position.
US09174686B1 Military vehicle
A vehicle includes a chassis having a longitudinal centerline, a first axle and a second axle coupled to the chassis, a cab, a driver's seat, and a passenger seat. The cab is coupled to the chassis and includes a windshield assembly comprising a first side portion, a middle portion, a second side portion, a first pillar coupling the first side portion to the middle portion, and a second pillar coupling the second side portion to the middle portion. The driver's seat is disposed within the cab along the longitudinal centerline, and the passenger seat is disposed within the cab and longitudinally offset from the driver's seat to improve driver visibility.
US09174677B2 Automobile subframe
A joint part between a main body part of an automobile subframe and a suspension support member comprises a first joint part in which an upper plate is directly superimposed on and joined to the suspension support member, and a second joint part in which a lower plate is directly superimposed on and joined to the suspension support member, and since the first and second joint parts extend in the vehicle body fore-and-aft direction without overlapping each other, it becomes possible to directly transmit, to both the upper plate and the lower plate, a load that has been inputted from the suspension arm to the suspension support member, thus enhancing the joining strength of the main body part and the suspension support member. The upper plate and the lower plate are joined to the suspension support member from the same side.
US09174676B2 Method for executing an at least semi-autonomous parking process of a vehicle and parking assistance system for a vehicle
The invention relates to a method for executing an at least semi-autonomous parking process of a vehicle (13) by means of a parking assistance system (15), in which ambient conditions of the vehicle (13) are sensed as it travels past a potential parking space (3), and a parking path is determined as a function of the ambient conditions and of the parking space (3), wherein the ambient conditions comprise at least one obstacle (18, 18′, 18″) which is external to the parking space and does not directly bound the parking space (3) and is detected as near to the vehicle and is taken into account in the determination of the parking path (3), wherein the parking process is executed in a plurality of maneuvers (26, 27, 29; 34, 38, 39), and at least one maneuver (26, 27, 29; 34, 38, 39) which is executed with an autonomous steering intervention is determined in terms of its profile as a function of the obstacle (18, 18′, 18″). The invention also relates to a parking assistance system (15) for a vehicle (13).
US09174672B2 Path planning for evasive steering maneuver in presence of target vehicle and surrounding objects
A method for calculating a virtual target path around a target object that includes providing scan points identifying detected objects and separating the scan points into target object scan points and other object scan points. The method identifies a closest scan point from the target object scan points and identifies a path point that is a predetermined safe distance from the closest scan point. The method determines a straight target line adjacent to the target object that goes through the path point, and determines a distance between the target line and each of the other objects and determines whether all of the distances are greater than a predetermined threshold distance. The method identifies curve points for each other object whose distance is less than the predetermined threshold distance, and identifies a curve path that connects the curve points to be the virtual target path using a quadratic polynomial function.
US09174664B2 Operating device for steering a vehicle and method for steering the vehicle
An operating device for steering a vehicle, in particular a motor vehicle, and a method for steering the vehicle by way of the operating device. The operating device comprises a control stick, in particular for operation by a human hand. The control stick has at least one degree of freedom. A steering angle can be specified by way of the control stick. The operating device comprises a control element. The specifiable steering angle can be determined as a function of a state of the control stick and as a function of a state of the control element.
US09174663B2 Snow rider
The Snow Rider provides a rider with a platform that is stable, simple to use, and provides a significant amount of control for the rider. The Snow Rider makes use of two pairs of parallel-oriented articulated skis that are interconnected by a platform on which the rider's bindings are attached. The front and back end of the platform are connected to respective front and rear articulated segments of the pair of skis via control linkages which include trucks that translate leaning by the rider into a redirection of the Snow Rider and by simultaneously operable outriggers which get the skis up on edge and in contact with the snow as they are turned. The rider can either face the direction of motion as with skis or perpendicular to the direction of motion as with a snowboard.
US09174661B2 Armrest folding device for a foldable stroller
A foldable stroller includes a stroller frame having two side frame portions, each of which includes a push rod, a leg rod, a pivot joint, and an armrest assembly including an armrest and an armrest folding device. The pivot joint has an upper joint member connected to the push rod, and a lower joint member connected to the leg rod. The armrest folding device includes: a connecting unit connected fixedly to the armrest, connected pivotally to the lower joint member, and having a guide slot formed therethrough; and a guide pin connected to the the upper joint member and extending through the guide slot. When the push rod is rotated relative to the leg rod, the guide pin moves between too opposite ends of the guide slot to thereby rotate the connecting unit relative to the lower leg rod.
US09174659B2 Handle for shopping cart
A shopping cart includes a frame, a plurality of wheels for supporting the frame for movement over a floor, an arm connected to the frame, and a projection positioned proximate at least one of the wheels. The frame has a front end and a rear end. The arm is configured to engage the tow member for moving the frame. The projection engages the guide member to prevent one of the front end and the rear end from rotating over the other of the front end and the rear end. A handle assembly may include an elongated slot positioned proximate a handle. The shopping cart may also include a tray is releasably secured to the frame by inserting a tab into a slot. The shopping cart may also include a tab received within a slot to secure a basket against movement relative to the frame.
US09174657B2 Automated real-time positive train control track database validation
Methods and systems are described that can be used to verify a track database of a train management system, for example that the track database has not been corrupted, built with critical errors, or is not being used properly by the software application. In one embodiment, radio frequency identification (RFID) tags are mounted on the trackside features contained in the track database. The tags contain data such as the geographical coordinates of the trackside features and a unique feature identifier that uniquely identifies the respective feature. As the train passes the trackside feature, a tag reader on the train reads the tag to gather the geographical coordinates and the feature identifier. The train management system then compares the geographical coordinates and/or the feature identifier from the tag with the expected geographical coordinates and/or the expected feature identifier in the track database.
US09174652B2 System and method for reducing driving skill atrophy
A system for preventing driving skill atrophy comprises a trainer module that determines the driver's current skill level, disables certain automated features based on the determined skill level, and forces the driver to use and hone her driving skills. The system collects data to determine through on-board vehicle sensors how a driver is driving the vehicle. The system then compares the driver's current driving skills with the driver's historical driving skills or the general population's driving skills. Based on the comparison, the system determines whether the driver's skill level is stagnant, improving or deteriorating. If the skill level is improving, for example, the system disables certain automated driving features to give driver more control of the vehicle.
US09174651B2 Method and circuit arrangement in an electronic control unit of a motor vehicle for detecting faults
In the case of a circuit arrangement in an electronic control unit of a motor vehicle for the detection of faults in an electronically controlled drive system, which is structured in at least two levels, a first function-controlling level and a second monitoring level, both levels acquire at least the accelerator pedal position as an input signal. The first level has a driver intention determination block for determining a quantity proportional to the desired longitudinal acceleration. The first level transmits this quantity as an input signal to a plausibility block of the second level. The plausibility block has at least one fault detection program, by which a fault can be detected when a defined correct relationship does not exist for a specified time period between the accelerator pedal position and/or the accelerator pedal position change with respect to the determined quantity proportional to the desired longitudinal acceleration—and this relationship is therefore implausible.
US09174649B1 Redundancy for automated vehicle operations
A vehicle sub-system controller is configured to receive a first message and a second message, wherein the first message includes at least a command for the controller, and the second message includes at least a target value for the controller to achieve. A fault may be detected with respect to the first message; and an adjustment to the sub-system may be locally determined in the sub-system controller to achieve the target value.
US09174637B2 Methods and systems for torque control
Methods and systems are provided for improving surge control. When surge conditions are approached, a reference governor reduces engine airflow at a slower rate and to a higher level than the engine airflow required to meet the reduced torque demand. The excess torque resulting from the extra airflow is offset by applying a negative torque on the driveshaft via an electric machine coupled to the engine or via alternate engine actuator adjustments.
US09174626B2 Methods and systems for controlling shifting between operating modes in hybrid vehicles
A method for controlling shifting between a plurality of operating modes in a hybrid vehicle includes the steps of obtaining a plurality of throttle position values, generating a comparison between a first throttle position value of the plurality of throttle position values and a second throttle position value of the plurality of throttle position values, and selectively allowing a shift between at least two of the plurality of operating modes, based at least in part on the comparison between the first and second throttle position values.
US09174623B2 Abnormality detection apparatus for braking force detector
A braking force detector detects the braking force of a vehicle or a value based on which the braking force can be calculated. A steering torque sensor detects a steering torque of a steering wheel. A lateral acceleration sensor detects a lateral acceleration of the vehicle. A turning/braking judgment unit judges whether or not the vehicle is braking while turning. When the vehicle has been judged to be braking while turning, an abnormality judgment unit judges based on the steering torque and the lateral acceleration whether or not an abnormality has occurred in the braking force detector.
US09174622B2 Parking brake system
A vehicle parking brake system for a vehicle including: a non-rotary body; a rotary drum; brake shoes; an anchor member disposed between anchor-member-side end portions of the respective brake shoes; a transmitting member interconnecting transmitting-member-side end portions of the respective brake shoes; and a parking-brake operating apparatus configured to predict a torque application direction in which a torque is to be applied to the wheel during stop of the vehicle, and to press the brake shoes against an inner circumferential surface of the rotary drum, by moving a primary one of the brake shoes that serves as a primary shoe upon application of the torque to the wheel, in a direction away from the anchor member, without moving a secondary one of the brake shoes that serves as a secondary shoe upon application of the torque to the wheel.
US09174620B2 Slip control braking pump having a high pressure sealing structure
A vehicular hydraulic braking pump includes a sleeve having an inner bore defining an inner bore surface and a piston having a stop collar and a ramped seal face. The stop collar, ramped seal face, and the inner bore cooperating to define a seal pocket which traps a high pressure seal therein. The ramped seal face provides contact of the high pressure seal to the sleeve inner bore that is proportional to fluid pressure acting on the high pressure seal.
US09174619B2 Multiple-mode braking system
An all-in-one braking system for a vehicle is described. The braking system includes an operating rod, a first piston system, a second piston system, and a fail safe plate. The operating rod is couplable to a brake actuator operated by the driver of the vehicle. The first piston system and the second piston system each include a piston, a fail recovery key, and a motor. The motor is coupled to the piston to affect lateral movement of the piston which, in turn, causes a braking pressure to be applied to a wheel of the vehicle. The fail safe plate is fixedly coupled to the operating rod such that lateral movement of the operating rod causes lateral movement of the fail safe plate. A controller is configured to operate the motors to control the lateral movement of the pistons based at least in part on detected movement of the operating rod.
US09174618B2 Brake and braking actuation units
A brake may include a bellows having an opening that leads into the interior of the bellows, a brake element joined to the bellows, a rotational element arranged at a distance from the brake element, a fluid reservoir or a pressure production unit, and a first conduit between the fluid reservoir or the pressure production unit and the opening.
US09174614B2 Safety brake system for trailers
A safety brake system for a trailer comprises a brake end, an actuation end and a biasing unit. The brake end comprises a brake unit adapted to be secured to a trailer and positioned to block at least one wheel of the trailer when actuated. The actuation end comprises a mount adapted to be secured to a front end of the trailer and a probe operatively supported by the mount for displacement with respect to the trailer. The probe is operatively connected to the brake unit for actuating same. The probe is displaceable between a hitching state in which the probe is adapted to contact the hitch of a vehicle, and a braking state in which the probe actuates the brake unit. The biasing unit biases the probe against the hitch of the trailer in the hitching state and toward the braking state, such that the brake unit is actuated when the hitch is separated from the trailer.
US09174612B2 Viscous brake for driveline heating
Embodiments for heating a vehicle driveline are provided. One example method for a vehicle comprises heating a fluid with kinetic vehicle energy in response to a vehicle braking request, and directing the fluid to a driveline component. In this way, kinetic vehicle energy during a vehicle braking event may be used to heat a driveline component.
US09174605B2 Pedestrian airbag cushion
Disclosed is a pedestrian airbag cushion. The pedestrian airbag cushion includes a cushion inflated to cover a windshield glass by an inflator, with a vent hole formed in the cushion. A tether is provided on a portion of the cushion corresponding to a driver's seat and is connected at a first end to an upper portion of the cushion. The tether extends downwards and is connected at a second end to a lower portion of the cushion. The tether has a contractive force to pull the portion of the cushion corresponding to the driver's seat downwards after the cushion is deployed.
US09174603B2 Air bag with tear stitched tether
An apparatus for helping to protect an occupant of a vehicle includes an inflatable vehicle occupant protection device inflatable between a vehicle surface and the vehicle occupant. The protection device includes a front panel having a portion presented toward the occupant when the protection device is in an inflated condition. A vent includes at least one opening for releasing inflation fluid from the protection device and has an actuated condition and a non-actuated condition. A tether has a first segment connected to the vent and the front panel of the protection device for actuating the vent and a second segment connected to the front panel and a rear portion of the protection device. Tear stitching connects portions of the second segment of the tether to form a slackened portion of the tether. The tear stitching remains intact such that the first segment is slackened and the vent in the non-actuated condition in response to initial deployment of the protection device below a predetermined degree. Further deployment of the protection device to the predetermined degree causes the tear stitching to rupture and release the slackened portion, which allows the first segment of the tether to tension and act on the vent to place the vent in the actuated condition.
US09174599B2 Adjustbale pet fence in vehicle
A pet fence includes a first part having multiple first bars, and two second parts each having multiple second bars are slidably connected to the first part. Two positioning tubes are connected to the first part and each have first holes and second holes. Multiple adjustment units connect the first part to the second parts, and each adjustment unit is cooperated with a locking unit which extends through one of the first holes the positioning tubes. When the locking unit is loosened, the two second parts are movable relative to the first part to adjust the width of the pet fence. At least one clamp unit is connected to one of the second holes of the positioning tube to secure the at least one clamp unit to the headrest rod the seat of a vehicle.
US09174589B2 Vehicle trim structure with integrally formed ribs
A vehicle trim structure for attachment of a resilient clip includes a flange extending generally orthogonally from an interior wall of an automotive vehicle and a plurality of ribs protruding generally orthogonally from the flange. The flange includes a proximal end integral with the interior wall, a distal end separated from the interior wall, an interior face spanning between the proximal end and the distal end, and an exterior face spanning between the proximal end and the distal end, opposite the interior face. The plurality of ribs extends longitudinally from the proximal end of the flange to the distal end of the flange.
US09174588B2 Mounting a microphone on a vehicle headliner
A headliner assembly for a vehicle includes a headliner and a microphone. The headliner is configured for attachment to the vehicle such that the headliner separates a passenger cabin of the vehicle from a roof panel of the vehicle and such that a first surface of the headliner faces the roof panel, and an opposite, second surface of the headliner faces the passenger cabin. The microphone is mounted along the second surface of the headliner such that, when installed in the vehicle, the headliner is disposed between the microphone and the roof panel.
US09174587B2 Positioning apparatus for seat headrest posts in vehicle
A positioning apparatus for seat headrest posts in vehicle is provided, including a retractable rod, two clamping units and a connection joint unit; wherein the retractable rod having an extendible rod able to extend and retract; a locking assembly being disposed on the outer surface of the retractable rod; the locking assembly being able to fasten the position after lateral adjustment of the retractable rod; the two clamping units being disposed on the retractable rod for clamping onto the posts of seat headrest; the connection joint unit being disposed to the end of the extendible rod for engaging an object to be mounted here. As such, when an electronic device, such as, tablet or thin screen display is mounted to the connection joint unit, the position of the electronic device can be adjusted by adjusting the length of the extendible rod for convenient viewing.
US09174584B1 Bicycle carrier for vehicle
A bicycle carrier for a vehicle may include guide rails symmetrically disposed at both sides of a rear bumper beam and extending in a front-rear direction of the vehicle, a sliding rail including a panel and sides extending from the panel, and sliding forward and backward on the guide rails, an expanding link disposed between the sides of the sliding rails and including a plurality of links connected such that a lateral gap between the links increases, when a front-rear gap between the links decreases, support arms disposed on the expanding link to move laterally with the expanding link, slidably engaged with the sliding rails, and fixing a loaded bicycle, and an actuating unit fixed to the rear bumper beam, including a link assembly connected to the sliding rail and the expanding link, and providing power through the link assembly during operation to move the sliding rail and expand or contract the expanding link.
US09174575B2 Driver prompting braking system and method
A driver prompting braking system includes a detection device adapted to sense at least one object in front of the vehicle; a detection system interfacing with the detection device, the detection system adapted to detect the at least one object; and a brake coaching system interfacing with the detection system, the brake coaching system adapted to determine a brake application timing for an operator of the vehicle to avoid the object and optimize fuel economy of the vehicle. A driver prompting braking method is also disclosed.
US09174574B2 Vehicle vision system for controlling a vehicle safety feature responsive to an imaging sensor having an exterior rearward field of view and before a collision occurs
A safety system for a vehicle includes an imaging sensor and an image processor. The image sensor has an exterior rearward field of view. The imaging sensor captures image data and the image processor is operable to process captured image data to detect an object approaching the subject vehicle from rearward of the subject vehicle. The safety system is operable to determine if the detected object is likely to collide (or that a collision is probable or imminent or unavoidable or substantially unavoidable) with the subject vehicle and is operable to adjust a safety feature of the vehicle before the collision occurs. The safety system may be operable to adjust or vibrate or reposition a headrest of a seat in the subject vehicle responsive to determination that the detected object is likely to collide with the subject vehicle.
US09174572B2 Electric horn device for a vehicle and vehicle
Electric horn devices for a vehicle and vehicles with the electric horns are provided. An electric horn device includes a housing that is tightly sealed, a housing section within the housing, and a membrane element within the housing and configured to generate a sound. An elastic pressure equalizing element is adapted to allow pressure equalization in the housing.
US09174571B2 Tilt switch and lighting assembly for a vehicle compartment
A vehicle compartment has a housing defining a space and an access door pivotally coupled to the housing for pivoting between an open position and a closed position. Included is a light source for illuminating the space and a tilt switch provided on a circuit board coupled to the access door. The tilt switch is configured to have a first switch position when the access door is in the closed position and a second switch position when the access door is in the open position. The light source is activated when tilt switch is in the second switch position. The compartment may include a storage compartment, such as a glove box. The compartment may include an engine compartment.
US09174568B2 Headlamp mounting bracket energy absorber
The present disclosure is directed a thermoplastic energy absorbing headlamp mounting bracket comprising a frame having a proximal end and a distal end, and an energy absorbing member having a proximal end affixed to the proximal end of the frame, a distal end extending at least partially over the distal end of the frame, and an arcuate central portion extending between the distal end and the proximal end of the energy absorbing member. The proximal end of the energy absorbing member is configured to operably couple to a portion of the headlamp, and the frame is frictionally slidable in relation to the distal end of the energy absorbing member. Headlamps and vehicles comprising the energy absorbing headlamp mounting bracket are also disclosed.
US09174566B1 Reminder method and apparatus for a motor vehicle driver
An apparatus and method for reminding a motor vehicle driver to take some action before exiting the vehicle. A reminder ribbon apparatus is disclosed. One end of the reminder ribbon is held in place at the driver's right side, as by being attached to the strap bracket anchoring the female seat belt buckle to the vehicle. The other end of the reminder ribbon is attached, as with a spring clip, to the seat belt when the seat belt buckle assembly is engaged to place the seat belt in the use position across the driver's torso. When the seat belt buckle assembly is disengaged, the reminder ribbon is drawn across the driver's torso by the automatically retracting seatbelt. The driver is reminded, by the presence of the ribbon across his torso, to take an action, for example to attend to a child in the back seat of the vehicle, before exiting.
US09174564B2 Interchangeable strap connectors
Hooks are provided which permit the removable attachment to loop members of tie-downs straps of the type used to tie-down cargo. In one example, a modified J-hook is provided where the two hook that form the hook members on the end of the J-hook are separated from one another and create a gap between the members to permit the threading of the hook to loop member of the tie-down straps. In another example, a modified ring-hook is provided with overlapping end members for removable receiving the loop members of the tie-down straps.
US09174561B1 Article reception device for vehicles
An article reception device for vehicles with an article reception portion for being interposed in the gap between the vehicle seat and the central console and an article return container with an open inner volume contiguous with an open inner volume of the article reception portion. Articles dropped into the gap can be received by open inner volume of the article reception portion, and articles received by the article reception portion can be passed into the open inner volume of the article return container for retrieval. A seatbelt can pass through an aperture in the article reception portion. The article return container can project beyond the article reception portion longitudinally and laterally. The article return container can be selectively retained relative to either the first end or the second end of the article reception portion.
US09174557B2 Vehicle seat
An S-spring 14 is provided in a state of tension between a pair of seat back frames 10 constituting a vehicle seat 1. A support section 16a of a bracket 16 fixed to the seat back frame 10 supports a part of an end of the S-spring 14 from behind. The support section 16a is formed with a length equal to or greater than one pitch of the S-spring 14 in a no-load state and discontinuously supports center portions α of the S-spring 14. When a load equal to or greater than a predetermined level acts on the S-spring 14, the S-spring 14 is stretched to cause the center portions α to be dislocated from the support sections 16a, and as a result, the length of a deflectable portion of the S-spring 14 is changed.
US09174550B2 Electric vehicle driving support system
An electric vehicle driving support system includes an acquisition unit that acquires predictive information of traffic congestion calculated based on acceleration of an electric vehicle and an economical driving mode output unit that outputs a control instruction to prioritize speed maintenance or acceleration when the predictive information of traffic congestion acquired by the acquisition unit indicates a non-congestion tendency, and that outputs a control instruction to prioritize deceleration when the predictive information of traffic congestion indicates a congestion tendency.
US09174545B2 Vehicle charging device
Provided is a vehicle charging device (170) that uses a power source (101) outside of a vehicle (160) to charge a battery (115) installed in the vehicle (160). A charger (114) charges the battery (115). A voltage measurement unit (111) measures the input voltage corresponding to the input current in the charger (114). A current measurement unit (112) measures the input current (Ic) in the charger (114). A control unit (113) changes the input currents (Ic) of the charger (114) into a plurality of values, and controls the input current (Ic) when the input voltage (Vc) has changed, according to the corresponding relationship between the input currents (Ic), when each has been changed, and the measured input voltages (Vc).
US09174542B2 Power supply device for vehicle
The invention has an object of providing a power supply device for vehicle of high efficiency while keeping longer service life of a capacitor. By supplying an electric power of a capacitor to various electronic devices for a first predetermined time period after a vehicle engine has been stopped and discharging an electric power of the capacitor to a battery for a second predetermined time period after the first predetermined time period has ended, the voltage of the capacitor is reduced. By forcing the electric power of the capacitor to discharge at a forced discharge circuit until the voltage of the capacitor is substantially equal to a predetermined voltage after the second predetermined time period has ended, the time period during which the capacitor is held at a high voltage is made shorter. Longer service life of the capacitor and higher efficiency of the power supply device can be achieved.
US09174536B2 Functional unit with button functions
The invention relates to a method of producing a multifunctional functional unit with a rigid support structure, in which control elements and/or display elements are arranged behind a transparent surface layer which is continuous over substantially the entire functional unit. The method includes punching a positioning hole in a transparent plastic film with a thickness in the range of 0.1-0.4 mm; positioning the film into an injection mold using the positioning hole, with a corresponding positioning means for engaging in the positioning hole; back-injecting film to form a plastics support on the first side, the injection mold being designed such that, of the plastic film is not back-injected at the control elements and/or display elements, on the second side the plastics film is flooded with a transparent curing casting compound to form a continuous transparent surface layer.
US09174532B2 Fuel tank slosh absorber
A fuel tank includes a structural body and a membrane. The membrane extends vertically between and is attached to a top wall and a bottom wall of the structural body, and substantially extends between a first side wall and a second side wall of the structural body. The membrane defines a plurality of venting apertures operable to allow liquid fuel to move therethrough. The membrane is flexible, and includes a length, measured between a top edge and a bottom edge of the membrane, that is greater than a height of the structural body, which is measured between the top wall and the bottom wall of the structural body. The flexibility of the membrane and the length of the membrane allow the membrane to flex and move to absorb kinetic energy of fuel moving within the structural body.
US09174527B2 Electric grill shutter control device
An electric grill shutter control device includes: a control portion that performs an energization of a motor that drives a movable member that configures the electric grill shutter; a detection portion that detects a rotational speed of the motor; a determination portion that determines whether locking of the movable member is occurred based on whether the energization is performed and the rotational speed; and an identification portion that obtains a rotation amount of the motor in a period around the locking from the rotational speed in a case where the locking occurs and identifying a cause of the locking according to the rotation amount and the energization.
US09174526B2 Drive controller for vehicle
In a drive controller for a vehicle including: a drive source configured to output a drive force to a first axle serving as one of front and rear wheel axles; an electric motor configured to output a drive force to a second axle serving as the other of the front and rear wheel axles; a one-way power transmission device disposed on a power transmission pathway between the second axle and the electric motor so as to transmit a power drive force from the electric motor to the second axle; a two-way power transmission device that transmits a rotation power from the second axle to the electric motor or transmits the power drive force and a regeneration drive force from the electric motor to the second axle, the drive controller includes: a first detector that detects a speed of the vehicle or a rotation speed of the second axle; a target rotation speed determination section that determines a target rotation speed of the electric motor based on the speed of the vehicle or the rotation speed of the second axle; a second detector that detects a rotation speed of the electric motor; and a controller that controls the electric motor such that the rotation speed of the electric motor is synchronized with the target rotation speed and that controls an output torque of the electric motor or an activation of the two-way power transmission device, when the electric motor starts power drive or regeneration drive while the vehicle is traveling by the drive force from the drive source.
US09174523B2 Power transmission system of hybrid electric vehicle
A hybrid-electric power transmission system may include: an input shaft; an output shaft; a first planetary gear set on the input shaft, and including a first rotation element connected to a first motor/generator, a second rotation element connected to the output shaft, and a third rotation element directly connected to the input shaft; a second planetary gear set on the input shaft, and including a fourth rotation element directly connected to a second motor/generator and selectively connected to the third rotation element, a fifth rotation element connected to the output shaft, and a sixth rotation element connected to a transmission housing; transfer gears; and frictional elements selectively connecting two rotation elements among three rotation elements of the second planetary gear set, selectively connecting the third rotation element to the fourth rotation element, or selectively connecting the sixth rotation element to the transmission housing.
US09174518B2 Omnidirectional gripping surface for sheet materials
A clamping device for attaching or holding a sheet material has an upper clamping surface on an upper jaw with a series of protuberances formed with at least a curved shape about a center of a sheet material clamp, and a lower clamping surface on a lower jaw member having a series of protuberances which mate with the upper clamping surface protuberances in a nesting manner, such that closing of the sheet material clamp brings the upper clamping surface and the lower clamping surfaces into a nesting juxtapositioned position, thereby capturing a sheet material between the surfaces using compression or crimping. The pattern of protuberances may be concentric circular protuberances, other closed geometric protuberances, or semi-circular with rounded or tapered ends to avoid presentation of a sharp edge to a clamped sheet material.
US09174515B2 Method of assembling a slider window assembly
A method of assembling a slider window assembly for a vehicle includes providing at least one fixed window panel defining an opening with an upper frame portion and a lower frame portion fixed relative to the fixed window panel. A movable window panel is loaded at the upper and lower frame portions by (i) inserting a lower portion of the movable window panel into a portion of a lower channel element of the lower frame portion to a first depth, (ii) aligning an upper portion of the movable window panel with an upper channel of the upper frame portion, (iii) raising the movable window panel so that the upper portion is at least partially received in the upper channel and the lower portion is at a second depth to generally align with a receiving portion of the guide element, and (iv) moving the lower portion into the guide element.
US09174514B2 Glass operation based on temperature input/vehicle speed, final logic decided by customer
A system and method for operating a window of an automotive vehicle having a convertible top includes at least one powered window selectively driven by a motor. A controller is operatively connected to the motor and sends a signal for positioning the powered window to one of a raised or lowered position in response to lowering of the convertible top. An input or selector is operatively associated with the controller that allows a user to select one of the raised and lowered positions of the at least one powered window in response to lowering the convertible top. Further, a temperature sensor provides a signal indicative of the external temperature and/or a vehicle speed sensor provides a signal indicative of the vehicle speed so that positioning of the window can be temperature dependent and/or vehicle speed dependent.
US09174509B2 Vehicle axle suspension system
A suspension system is provided for a movable, supported vehicle axle. The suspension system includes a pair of hydraulic suspension cylinders, which are placed between the vehicle axle and a supporting vehicle structure. Each hydraulic suspension cylinder includes a first work chamber connected to a first pressure accumulator, and a second work chamber connected to a second pressure accumulator. A pressure-limiting valve is exposed to pressure in the first work chamber and has an outlet connected to the second pressure accumulator.
US09174506B2 Chassis system for commercial vehicles
A chassis system for commercial vehicles includes an axle stub element and a linkage element, wherein the linkage element has a recess and the axle stub element has a first mounting section, wherein the first mounting section is arranged in the recess of the linkage element and is force-locked at the recess due to a shaping process, and wherein an adhesive layer, via which a material band is formed between the first mounting section of the axle stub element and the recess of the linkage element, is provided between the first mounting section and the recess.
US09174505B2 Vehicle independent suspension
An independent suspension (10) of a vehicle includes a knuckle (22) intended to carry a wheel (W), a damper (12) connected at a bottom end thereof to the knuckle (22), and a plurality of arms (14, 24) connected to a body (B) of the vehicle and the knuckle (22). A hinge device (30; 34) is interposed between the damper (12) and knuckle (22) to allow the damper (12) and knuckle (22) to rotate relative to each other about an axis of articulation (H) that is oriented to form an acute angle with a horizontal. A torsional stiffness control device (32; 34; 34, 70) is interposed between the damper (12) and knuckle (22) to control torsional stiffness of an articulated connection between the damper (12) and knuckle (22) about the axis of articulation (H).
US09174499B2 Pneumatic tire
The present invention relates to a pneumatic tire 1 in which turbulent-flow generating projections 10 each extending from an inner circumference side to an outer circumference side are provided on a outer circumferential face 3a which is tire surface of tire side portion 3 at intervals in a tire circumferential direction. Each of the turbulent-flow generating projections 10 includes an edge portion 10g when being viewed in a cross-sectional shape taken along a direction perpendicular to an extending direction thereof, and a front wall angle θ formed between a front wall face 10a of each turbulent-flow generating projection 10 and the tire surface (outer circumferential face 3a) is set in the range of 70° to 110°, the front wall face being hit by an airflow.
US09174497B2 Pneumatic tire with tread having chamfered circumferential groove portion of bent auxiliary groove
A pneumatic tire comprises a tread provided with at least two circumferential main grooves and a rib defined in a tread central portion by the circumferential main grooves, wherein an auxiliary groove is formed in the tread central portion, the auxiliary groove having a circumferential groove portion extending in a tire equator direction and an axial groove portion extending from an end of the circumferential groove portion in such a manner that the axial groove portion is bent at an acute angle to the circumferential groove portion, and at least an end of the auxiliary groove is open into the circumferential main groove.
US09174489B2 Tire for vehicle including reinforcements in the sidewalls
A tire comprising a carcass-type reinforcement structure and beads, each bead being extended radially outwardly by a sidewall, the sidewalls meeting radially outwardly with a tread, the intersection of the sidewalls and of the tread defining the shoulder ends of the tire. The tire includes, in the area of each of the sidewalls, at least one layer of materials having a stretch rigidity in the longitudinal direction greater than 5000 daN/mm and the radially outer end of said layer of materials is radially inside the shoulder ends of the tire.
US09174472B2 Printer
The disclosure discloses a printer comprising a take-up portion, a first memory, a consumed amount calculating portion, a first correcting portion, an operation signal input portion, and a second correcting portion. The take-up portion takes up a recording medium on which printing was performed by the printing head. The first memory stores a value related to a remaining amount or a consumed amount of the recording medium. The consumed amount calculating portion calculates a first consumed amount based on a fed amount by the feeder. The first correcting portion corrects the value stored in the first memory by the first consumed amount. The second correcting portion corrects the value r stored in the first memory by using a predetermined second consumed amount, triggered by input of the operation signal to the operation signal input portion.
US09174468B2 Recording apparatus
The disclosure discloses a recording apparatus comprising a take-up body, a recording speed determining portion, a total length acquiring portion, and a take-up time determining portion. The take-up body sequentially takes up a recorded medium around a predetermined axis and produces a roll-shaped recorded matter. The recording speed determining portion determines a recording speed by a recording head based on a medium information acquired by a medium information acquiring portion. The total length acquiring portion acquires a total recording length by the recording head. The take-up time determining portion predicts and determines a take-up time by the take-up body before the take-up body starts take-up of the recorded medium, based on the total recording length acquired by the total length determining portion and the recording speed determined by the recording speed determining portion.
US09174465B2 Printer
A duplex printer with a small, compact conveyance path has a medium supply path and a medium inverting path that merge into a middle conveyance path at a junction. The middle conveyance path goes to a path switching unit connecting a main conveyance path and the inverting path. A flap, which is a path switching member, is disposed in the path switching unit. A middle conveyance roller pair, having a middle conveyance roller and a nipping portion, conveys the medium (e.g. paper) through the middle conveyance path. The portion of the middle conveyance path from at least the junction to the nipping portion is a conveyance path portion defined by the roller surface of the middle conveyance roller. The paper fed to the middle conveyance path is guided by the middle conveyance roller from the junction to the nipping portion of the middle conveyance roller pair.
US09174458B2 Heating device for detecting state of adjustment portion that adjusts period of connection with alternating current source
In a heating device, a heater has first and second terminals. The first terminal is connectable to an alternating current source. The adjustment portion selectively establishes and disconnects a first connection between the second terminal and the alternating current source. The switching portion selectively establishes and disconnects a second connection between the heater and the alternating current source. The generating circuit has a third terminal connected to the alternating current source and a fourth terminal connected between the second terminal and the adjustment portion. The generating circuit generates a zero-cross signal of the alternating current source. The processor is configured to: adjust a connection period during which the adjustment portion establishes the first connection; detect a state of the adjustment portion in response to the zero-cross signal; and perform an error process when the detected state of the adjustment portion indicates that the adjustment portion cannot disconnect the first connection.
US09174456B1 Printing device, notification method, and ink ribbon cassette
A printing device includes a printing mechanism that allows a loop-shaped ink ribbon to be detachably installed therewith, and applies an impact to the ink ribbon to transfer ink of the ink ribbon to a printing medium, a cumulative printed amount acquisition section that acquires a cumulative printed amount of the printing mechanism after the ink ribbon installed on the printing mechanism was last exchanged, a determination section that determines whether or not the cumulative printed amount acquired by the cumulative printed amount acquisition section has reached a predetermined first printing amount, or whether or not the cumulative printed amount has reached a second printing amount to be calculated based on the first printing amount, and an output control section that causes an output device to output a predetermined output if the determination section determines that the cumulative printed amount reaches the first or second printing amount.
US09174448B2 Ink jet recording apparatus and ink jet recording method
An ink jet recording apparatus is provided which includes a recording unit including a recording head having a surface provided with an ejection opening therein, an aqueous ink that is ejected from the ejection opening to record an image on a recording medium, a protection unit including a covering member that covers the surface having the ejection opening, and a recovery unit separate from the covering member, having no member that scrapes the ink deposited in the ink receiving member or sucks the ink from the ejection opening. The recovery unit includes an ink receiving member that receives waste ink discharged from the ejection opening according to preliminary ejection data, directly from the ejection opening without interposing any other member. The aqueous ink contains a self-dispersible pigment containing the carboxyl group or the sulfonate group.
US09174447B2 Liquid ejecting device facilitating replacement of cartridge
A liquid ejecting device includes a casing, a carriage, and a cartridge. The carriage is configured to move in a first direction and a second direction. The cartridge is configured to be removably mounted on the carriage and includes a first cartridge and a second cartridge. The first cartridge has a first grip part. The second cartridge has a second grip part. The carriage is configured to move between a first position where the first grip part is exposed and positioned outside the casing through a first opening and a second position where the second grip part is exposed and positioned outside the casing through a second opening.
US09174446B2 Digital printing press having a modular and reliable ink delivery system
A printing system that comprises a media transport system for conveying a print media along a media path in a first direction. A plurality of print modules each spanning the print media path along a second direction. Each print module defines a major axis along the second direction. A minor axis that aligns along the first direction and an intermediate axis with each of the print modules. A printhead array that includes printheads spaced from the media path. A fluid regulator portion configured to regulate a fluid pressure in the printhead portion. Each of the print modules are configured to be installed into and removed from the printing system as an integral unit.
US09174445B1 Microfluidic die with a high ratio of heater area to nozzle exit area
The present disclosure is directed to a microfluidic die having a substrate with an inlet path that is configured to move fluid into the die. The die includes a plurality of heaters formed above the substrate, each heater having a first area, a plurality of chambers formed above the plurality of heaters, and a plurality of nozzles formed above the chambers. Each nozzle having an entrance adjacent to the chamber and an exit adjacent to en external environment, the entrance having a second area, and the second having a third area, the first area being greater than the second area, and the second area being greater than the third area. A ratio of the first area to the third area being greater than 5 to 1.
US09174437B2 Liquid ejecting apparatus
Provided is a liquid ejecting apparatus including a first temperature sensor for detecting ink temperature and a second temperature sensor for detecting ambient temperature of a liquid ejecting head, in which a controller for controlling discharge of the ink generates a driving signal including a discharge voltage which is used for, based on a temperature detected by the first temperature sensor, discharging ink droplets through nozzle openings and a fine-oscillation voltage which is used for finely oscillating meniscuses of the ink without discharging the ink droplets and corresponds to the discharge voltage. Furthermore, the controller sets a coefficient in accordance with a temperature difference between the ink temperature and the ambient temperature and controls an energy level of the fine oscillation by applying the fine-oscillation voltage, based on the coefficient. In addition, the controller causes the discharge voltage to be applied to a pressure generation unit corresponding to the nozzle openings through which the ink droplets are discharged and causes the fine-oscillation voltage to be applied to a pressure generation unit corresponding to the nozzle openings through which the ink droplets are not discharged.
US09174426B1 Method of manufacturing a shrouded centrifugal impeller for high speed use
An apparatus and a process for producing a shrouded centrifugal impeller where a rear hub opening is machined into the stock material so that hard to reach surfaces in the enclosed passages can be machined. When the hard to reach passages are machined to a final stage, the rear hub opening is closed using a process such as electron beam melting or electron beam welding to enclose the passages and form a single piece shrouded impeller.
US09174418B1 Fireproof thermal insulation method
A multi-layer fireproof insulation roll for fireproofing and thermally insulating a tank car. The multi-layer fireproof insulation roll having a first layer with fire-retardant properties, a second layer having thermal insulating properties and a first strap. The first strap securing the first layer to the tank car. A method of fireproofing and insulating a tank car. A method of making a multi-layer fireproof insulation roll.
US09174413B2 Graphene based structures and methods for shielding electromagnetic radiation
Electromagnetic interference shielding structures and methods of shielding an object form electromagnetic radiation at frequencies greater than a megahertz generally include providing highly doped graphene sheets about the object to be shielded. The highly doped graphene sheets may have a dopant concentration greater than >1e1013 cm−2, which is effective to reflect the electromagnetic radiation or a dopant concentration of 1e1013 cm−2>n>0 cm−2, which is effective to absorb the electromagnetic radiation.
US09174411B2 Laminated sheet and process for producing the same
A laminated sheet is produced by forming an adhesion layer permeable to a liquid component and contactable with a skin on at least one side of a liquid-retention layer comprising a nonwoven structural member and having an ability to absorb the liquid component. The adhesion layer comprises a nonwoven structural member comprising a fiber having a number-average fiber diameter of not more than 10 μm, and the thickness ratio of the adhesion layer relative to the liquid-retention layer is 1/4 to 1/100 as a ratio of the adhesion layer/the liquid-retention layer. The fiber of the nonwoven structural member of the adhesion layer may have a standard deviation of fiber diameter of not more than 5. The nonwoven structural member of the liquid-retention layer may comprise a fiber having a fiber diameter larger than that of the fiber of the adhesion layer. The laminated sheet has a liquid retentivity and a liquid releasability in a well-balanced manner, and has an excellent adhesion and an excellent fit to the skin in the state where the sheet is impregnated with a liquid component.
US09174408B2 Multilayered packaging material
A multilayered polymeric structure for use as a packaging container comprising a first layer of oxygen barrier material and a second protective layer bonded to the first layer where the oxygen barrier layer material is selected from the group consisting of saponified ethylene-vinyl acetate copolymer, polyamide, polyvinyl alcohol, modification products thereof, and mixtures thereof, and the second protective layer comprises a polymer and an inorganic filler in an amount sufficient to further enhance the moisture barrier property of the outer protective layer over what it would be in the absence of the filler.
US09174407B2 Tray forming apparatus
A tray forming apparatus forms a blank into a tray having a double glued side wall construction for providing a desirable strength to the tray. A platen drives the blank through a forming rails which fold the blank into a partially formed tray having bottom, end and side walls, and inside corner supports formed about the platen. The platen is retracted prior to folding arms further extended portions of the partially formed tray. A compression plate and the folding arms are biased against adhesive portions of the tray for forming a fully formed tray having a double glued side wall construction.
US09174404B2 Method for manufacturing three-dimensional netted structure
A three-dimensional netted structure having an upper surface, a lower surface, two side surfaces a left end surface, and a right end surface, including at least a plurality of filaments helically and randomly entangled and thermally bonded together, wherein the filaments are formed out of a thermoplastic resin by extrusion molding followed by cooling with a liquid; and the netted structure is four-surface molded, the upper surface, the lower surface and the two side surfaces being molded. An apparatus and a method for manufacturing the three-dimensional netted structure.
US09174402B2 Method for manufacturing climate control duct, and climate control duct
A mold for manufacturing a climate control duct, which has a protrusion formed on an outer peripheral surface thereof and is formed from a foamed resin, includes a groove provided on at least a part of a surface of the mold for transfer of a shape of the protrusion. The groove of the mold satisfies a relation D
US09174401B2 Method for producing a multilayer data carrier and data carrier produced by said method
The invention relates to a method for producing a multilayer data carrier comprising a first layer which is made of plastic and has an upper face on which an opaque layer partially covering said upper face, for example a metal layer, is arranged. The data carrier has a second layer made of plastic which is disposed on the first layer and is transparent at least in a sub-region of the metal layer. The metal layer is partially removed by a laser to such an extent that the metal layer has at least one break. The metal layer is preferably laminated between the first and the second plastic layers.
US09174400B2 Method for producing structures in optoelectronic components and device for this purpose
A method for producing structures (5) on a multiplicity of optoelectronic components (1), wherein the multiplicity of optoelectronic components (1) are arranged on an auxiliary carrier (10) and the structures (5) are produced by carrying out a movement of a first roller (15) relative to the auxiliary carrier (10) and producing the structures (5) in the process by means of exerting a pressure between the first roller (15) and the auxiliary carrier (10).
US09174399B2 Manufacturing method of optical device, and optical device
In order to produce high-quality optical elements stably at all times without the flow of molten resin inside an injection molding cavity being hindered by the protrusion of the outer peripheral edge of a lens after compression molding, a cavity formed when a pair of molds for molding is closed is provided with: an optical-function-part molding cavity (27); an annular connection-part molding cavity (28) connected to the outer peripheral edge of the optical-function-part molding cavity; and an edge-part molding cavity (29) connected to the outer peripheral edge of the connection-part molding cavity. In a compression molding step, a protrusion part is formed by making a portion of a compression molding material bulge out from the connection-part molding cavity into the edge-part molding cavity (29). In an injection molding step, the molds are filled by injecting an injection molding material into the edge-part molding cavity (29). The resin of the protrusion part that has protruded from the connection-part molding cavity into the edge-part molding cavity (29) is biased toward one direction of the molds so as not to hinder the flow of the injection molding resin. The biased amount is set such that, when the cross section of the resin that has protruded into the edge-part molding cavity (29) is divided by a perpendicular bisector (L) that is perpendicular to the optical axis and that divides the thickness of the connection part in half, the cross-sectional area on the biased side includes greater than or equal to 60% of the cross-sectional area of the protruded resin.
US09174397B2 Aircraft plastics repair
A method for a repair of materials used in the manufacture of non-structural aircraft interior components includes the steps of laying fiberglass over a damaged surface and adhering the fiberglass with a fast-adhering glue, that includes at least one of cyanoacrylate and a cyanoacrylate activator for repairing the surface, to the damaged surface. A related method that includes applying a cyanoacrylate activator is used for removing pen and pencil marks for a synthetic leather material.
US09174395B2 Metal element based textile product with improved widthwise stability
A textile product and a method of making the same is described wherein the textile product includes a layer of metal elements, an array of stitches, and wherein the metal elements are encased between the legs of the stitch and the underlap of the stitch. Preferably, the overlaps and/or underlaps span between at least two stitch lines. This provides an improved metal element based textile product for preparing reinforced articles. The metal element based textile product of the present invention allows improved processing and improved performance as compared to conventional metal element based textile products.
US09174392B2 Method and device for switching a particulate material flow in the construction of models in layers
The invention relates to a method for switching a particulate material flow in the construction of models in layers, wherein particulate materials are fed to a subsequent method step from a container having an opening in the direction of a workpiece platform. The particles in the container are exposed to a vacuum and to overpressure.
US09174391B2 Device for producing three-dimensional models
The present invention relates to a device for manufacturing three-dimensional models by means of a 3D printing process, whereby a build platform for application of build material is provided and a support frame is arranged around the build platform, to which said support frame at least one device for dosing the particulate material and one device for bonding the particulate material is attached via the guiding elements and the support frame is moveable in a Z direction, which essentially means perpendicular to the base surface of the build platform, said movement provided by at least two vertical positioning units on the support frame. In this respect, it is provided that the positioning units are respectively separate components and are arrangeable on the support frame independently from one another and the location and orientation of such can be adjusted independently from one another.
US09174390B2 Integrated multi-material implants and methods of manufacture
Provided are methods and systems for fabricating multimaterial bodies in a layer-wise fashion, which bodies may be used bone-stabilizing implants. The multimaterial bodies include rigid and flexible portions that are integrally formed with one another. The multimaterial bodies may be softened or stiffened in specific areas to match the biological or anatomical features of a bone.
US09174389B2 Consumable assembly for use in extrusion-based layered deposition systems
A consumable assembly comprising a container portion configured to retain a supply of filament, a guide tube connected to the container portion, and a pump portion connected to the guide tube.
US09174385B2 Method and device for spatially periodic modification of a substrate surface
The invention relates to a method and a device for modifying in a spatially periodic manner at least in some regions a surface of a substrate (24), said surface being disposed on a sample plane (P) for which end different regions (211, 221, 231, 232) of the substrate surface are acted upon successively with a spatially periodic illumination pattern of an energy density above a processing threshold of the substrate surface, where the illumination pattern is generated by diffraction of an input beam (10) and superimposition of resulting, diffracted sub-beams (12, 14) by means of a grid interferometer (100), and where, in order to select the substrate surface region to be illuminated in each case (211, 221, 231, 232), the input beam (10) is deviated by means of a beam-deviating unit (16) arranged upstream of the grid interferometer (100).
US09174384B2 Multilayer polypropylene films and methods of making and using same
A method including forming a bilayer polymer film having an oriented polypropylene film and a metallocene-catalyzed polypropylene film wherein the metallocene-catalyzed polypropylene film has a seal initiation temperature of from 80° C. to 130° C. A laminate including a biaxially oriented polypropylene film, a metallocene-catalyzed polypropylene film, and a substrate, wherein the metallocene-catalyzed polypropylene film is disposed between the biaxially oriented polypropylene film and the substrate.
US09174380B2 Self-cleaning plasticizing venting and extruding apparatus by co-rotating non-twin multi-screws and method thereof
A self-cleaning plasticizing venting and extruding apparatus by co-rotating non-twin multi-screws and a method thereof are provided, said apparatus comprises a screw mechanism, barrel, feeding port, venting port, discharging port, and driving mechanism. Said screw mechanism comprises non-uniform central screw and lateral screws, the axis of the central screw coincides with the barrel, and the lateral screws are provided on both sides of the central screw and engaged with the central screw; the contour lines of the threads of said central screw and said lateral screws are tangent to the inner wall of the barrel; and said driving mechanism is connected to the central screw and lateral screws. Each screw-uses an asymmetrical flow channel shape, so the flow space is asymmetric, and the compounding intensity and effectiveness enhanced. The dispersion and mixing effects are excellent, generating a self-cleaning effect. The system is suitable for high yield nano-material processing.
US09174377B2 Multilayer blown films for shrink applications
The present invention discloses multilayer blown films for shrink label and related applications. These multilayer blown films can comprise a core layer containing an ethylene polymer, and inner and outer layers containing conjugated diene monovinylarene block copolymers.
US09174370B2 Fine paper powder-containing resin molded object and manufacturing method thereof
Provided is a fine paper powder-containing resin molded object with a content of a thermoplastic resin being reduced to offer a lighter weight and a superior mechanical strength, and a manufacturing method thereof. The fine paper powder-containing resin molded object (1) is made from a thermoplastic resin containing fine paper powder and is composed of a non-foam layer (2) formed on the surface and a foam layer (3) formed in the inner side. The foam layer (3) has, in the order from the surface side, a first foam layer (3a) containing cells having an average cell diameter ranging from 10 to 100 μm, a second foam layer (3b) containing cells having an average cell diameter from 5 to 50 μm, and a third foam layer (3c) containing cells having an average cell diameter from 20 to 500 μm. The molded object (1) contains an aromatizing ingredient.
US09174368B2 Retardation film, method of producing the same and image display device
The retardation film of the present invention contains at least one of an epoxy resin cured product and an epoxy (meth)acrylate resin cured product. In the retardation film of the present invention, in-plane birefringence index thereof at a wavelength of 590 nm is preferably 0.001 or more and a birefringence index in a thickness direction thereof at a wavelength of 590 nm is preferably 0.001 or more.
US09174367B2 Non-uniform cylinder
The present invention relates to an arrangement for treatment of articles by hot pressing and, in particular, by hot isostatic pressing. In particular, the present invention relates to a pressing arrangement for treatment of articles by hot pressing, and preferably hot isostatic pressing, capable of providing a controlled, rapid cooling rate. The pressing arrangement comprises a pressure vessel including a furnace chamber comprising a heat insulated casing and a furnace adapted to hold the articles. At least one cooling circuit is arranged on an outside of the pressure vessel, the cooling circuit comprising a coolant and being arranged to enable the coolant to flow along a central portion of an outer wall of the pressure vessel. The pressure vessel is arranged with a non-uniform wall thickness, where the vessel wall is thickest at upper and lower end portions of the pressure vessel.
US09174361B2 Method for simultaneously slicing a multiplicity of wafers from a cylindrical workpiece
A method for simultaneously slicing a multiplicity of wafers from a substantially circular-cylindrical workpiece that is connected to a sawing strip includes executing a relative movement between the workpiece and a wire gang of a wire saw with the aid of a forward feed device with a defined forward feed rate so as to slice the wafers. The forward feed rate is varied through the course of the method and includes being set to a value v1 at a cutting depth of 50% of the workpiece diameter. Subsequently, the forward feed rate is to a value v2>1.15×v1 as the forward feed rate passes through a local maximum. The forward feed rate is set to a value v3v3.
US09174359B2 Concrete saw
A concrete saw having a geared assembly for rotating a cutting blade is described. The saw utilizes a longitudinally oriented engine for rotating the blade. Various additional features and improvements are described including a particular belt tensioner assembly, an indicator and control system for cutting blade depth, a handle adjustment and locking system, and provisions for control of blade water are described.
US09174357B2 Extrusion-forming device
An extrusion-forming device includes an extruding portion having a drum including a supply port through which a clay flows into the inside, a screw having a rotary shaft and a rotary blade and configured to convey the clay, and an extrusion port through which the clay is discharged; and a forming portion having a die provided with forming grooves. The device includes, as the screw on the side of the supply port, supply port side screws having two rotary blades and, as the screw on the side of the extrusion port, a extrusion port side screw having one rotary blade, and a ratio P/D is in a range of 0.5 to 0.9.
US09174354B2 Power tool
A power tool has a driving shaft for driving a working element and a clamping device for clamping the working element. The clamping device has a clamping position in which the working element may be fixed relative to the driving shaft and a release position in which the working element can be removed from the driving shaft. An operating member is coupled to the clamping device for moving the clamping device between positions. The clamping device also has a rotating position in which the working element can be rotated by an angle relative to the driving shaft and the operating member has an operating position that corresponds to the rotating position.
US09174350B2 Multi-blade electric rotary razor
The present invention relates to a multi-blade electric rotary razor which comprises a razor blade cartridge turned by a motor, and at least one pair of razor blade assemblies disposed at an equal-angle distance at the razor blade cartridge along a direction in which the razor blade cartridge rotates, at least one pair of razor blades (hereinafter referred to as first razor blades) being arranged in an overlapping manner at a predetermined distance at the razor blade assembly along a radius direction of the razor blade cartridge. The electric rotary razor of the present invention has a structure of a wet shaver where multiple razor blades are arranged, and uses the motor to turn the razor blade cartridge during shaving for user convenience and thorough shaving. The multi-blade razor blade assembly alleviates a dermal stimulation, minimizes a possibility of a scar, and does not require shaving cream, making shaving convenient and unhindered by time and space.
US09174349B2 Rotary electric shaver
A rotary electric shaver includes a handle assembly having a housing, a motor disposed in the housing, a drive shaft operatively connected to the motor and extending through the housing, and a socket for securing a shaver head thereto. The shaver head assembly includes a coupling for detachable coupling to the socket. The coupling is configured to allow the shaver head to be detachably coupled to the handle assembly in at least two different orientations of the shaver head relative to the handle assembly.
US09174348B2 Cutting tool
The invention relates to a cutting tool (1) comprising: a first handle (2) and a first blade (3) fixedly attached to each other, a second handle (4) and a second blade (5) pivotably attached to each other by a first pivot (6) and a second pivot (7). In order to obtain a cutting tool with an optimal cutting force, the cutting tool comprises a limiter (11) allowing the back end (9′) to move sideways (S) in relation to the second handle (4) and preventing the back end (9) at least from moving away from the second handle (4) in an axial direction (A) of the first pivot (6).
US09174347B2 Retractable utility knife
A utility knife has a handle and a blade holder that holds a utility blade for selective removal and replacement of the utility blade. The blade holder is pivotally carried by the handle for pivotal movement in an arcuate path relative to the handle between a retracted position and an extended position.
US09174337B2 Saddle coupling and saddle base assembly for use with power hand tools
A saddle coupling and saddle base assembly is provided for use with power hand tools. The assembly is mounted atop a variably-adjustable stand for drilling holes or inserting fasteners into concrete ceilings, drywall ceilings or other overhead surfaces. The assembly comprises a saddle base and a saddle coupling that is removably attachable to the saddle base. The saddle coupling is configured to attach a single power hand tool or a plurality of power hand tools to the coupling. A plurality of like-configured saddle couplings can be attached to different power hand tools to allow the user to quickly and easily remove one saddle coupling and power hand tool and replace it for another. A spring-loaded locking feature is included in the assembly as a primary securement means for the assembly. A secondary securement means is also provided in the event of a failure of the primary means.
US09174333B2 Portable tool
The present application discloses a portable tool. In one embodiment, the portable tool comprises a body portion, a tool portion, and an attachment member for fastening the portable tool to a second device. The tool portion is coupled to the body portion and has one or more tools. The tool portion is configured to rotate about an axis of rotation and relative to the body portion. The attachment member is operatively coupled to the tool portion and rotates with the tool portion about the axis of rotation and relative to the body portion. Rotating the tool portion relative to the body portion exposes a space between the attachment member and the tool portion that permits release of the second device from the portable tool.
US09174331B1 Bushing removal tool
Gear pumps use various types of bushings or bearings (sleeves) between a shaft and the housing of the pump. From time to time, these sleeves wear out and have to be replaced. This extractor removes the sleeves and includes three main components—a collet or sleeve engaging member, a mounting bracket, and a lift screw. The extractor may also include other components within the scope of the invention, including melting screws and washers.
US09174322B2 Manufacturing method of semiconductor device
In accordance with an embodiment, a manufacturing method of a semiconductor device includes forming a polish target film on a substrate and conducting a CMP process for the polish target film. The conducting the CMP process includes bringing a surface of the polish target film into contact with a surface of a polishing pad with a negative Rsk value, and adjusting friction dependency on polishing speed between the polish target film and the polishing pad to a value that restrains the occurrence of a stick slip to polish the polish target film.
US09174314B2 Isothermal structural repair of superalloy components including turbine blades
Structural repair of cracks and other defects in superalloy components, such as steam or gas turbine blades in stationary or aero gas turbines, are performed by heating the blade substrate to an isothermal hold temperature below the substrate's incipient melting point and filling the crack with molten superalloy filler material. The molten filler solidifies into a casting and bonds with the component substrate at the isothermal hold temperature. Heat treatment processes are completed, so that the former crack is filled with cast superalloy material having identical or similar structural properties as the adjoining substrate superalloy material. The casting repair method may be utilized universally for all types of superalloy component defects, including those previously repaired by cosmetic, lower strength welding or brazing methods.
US09174309B2 Turbine component and a process of fabricating a turbine component
A turbine component and a process of fabricating a component are disclosed. The process includes excavating a base metal of the component to form a fill region and filling the fill region with a filler metal. The filler metal has a filler metal elongation that is at least 25% greater than a base metal elongation of the base metal. The filler includes, by weight, between about 4% and about 7% iron, between about 14% and about 17% chromium, between about 15% and about 17% molybdenum, between about 3% and about 5% tungsten, up to about 0.02% carbon, up to about 1% manganese, up to about 2.5% cobalt, and a balance of nickel and/or the filler metal elongation is greater than about 35% in/in per two inches.
US09174306B2 Laser processing method for nonlinear crystal substrate
A laser processing method for a nonlinear crystal substrate having a plurality of crossing division lines which includes the step of applying a pulsed laser beam to a work surface of the nonlinear crystal substrate along the division lines to thereby form a plurality of laser processed grooves on the work surface along the division lines. The pulse width of the pulsed laser beam is set to 200 ps or less and the repetition frequency of the pulsed laser beam is set to 50 kHz or less.
US09174300B2 Raster methodology, apparatus and system for electron beam layer manufacturing using closed loop control
A method for layer-by-layer manufacturing of a three-dimensional work piece, including: (a) delivering a metallic feed material into a feed region; (b) emitting an electron beam; (c) translating the electron beam through a first predetermined raster pattern frame that includes: (i) a plurality of points within the feed region; and (ii) a plurality of points in a substrate region that is outside of the feed region; (d) monitoring a condition of the feed region or the substrate region for the occurrence of any deviation from a predetermined condition; (e) upon detecting of any deviation, translating the electron beam through at least one second predetermined raster pattern frame that maintains the melting beam power density level substantially the same, but alters the substrate beam power density level; and (f) repeating steps (a) through (e) at one or more second locations for building up layer-by-layer.
US09174296B2 Plasma ignition and sustaining methods and apparatuses
An apparatus for generating plasma including a plasma generating vessel and a coil having a coil length and a first set of partially enclosing, longitudinally oriented conductive (PELOC) fingers and a second set of PELOC fingers. The PELOC finger sets are oriented along a longitudinal axis of the vessel with each partially enclosing a periphery of the vessel. The two sets of PELOC fingers are oriented fingertips facing fingertips and separated by an inter-set distance that is less than the coil length.
US09174295B2 System and method for configuring a TIG welding system using workpiece characteristics
A system and method for configuring a tungsten inert gas (TIG) welding system includes a user interface to receive characteristics of the workpiece to select operational parameters for the TIG welding process. The characteristics of the workpiece may include workpiece composition or workpiece thickness. Workpiece material is translated to an output welding-type power that is alternating current (AC) power or direct current (DC) power. Workpiece thickness is translated to a specific output amperage. The operator does not need to have knowledge of operational parameters of the TIG welding system and can configured the system using workpiece characteristics.
US09174294B2 Devices and methods for analyzing spatter generating events
A method for monitoring a spatter generating event during a welding application. The method includes capturing data that corresponds to a welding current of the welding application. The method also includes detecting parameters associated with a short circuit from the captured data. The method includes analyzing the detected parameters to monitor the spatter generating event during the welding application.
US09174293B2 Hardfacing process and parts produced thereby
A hardfacing process includes depositing a clad layer having a thickness greater than about 1 mm (0.04 in) on a surface of the component by arc welding, and creating a heat affected zone directly below the clad layer due to the depositing. The heat affected zone may be a region of the component where a lowest hardness is more than 40% lower than a base hardness of the component below the heat affected zone. The method may also include heat treating the component after the deposition such that the lowest hardness in the heat affected zone is restored to within about 15% of the base hardness of the component.
US09174291B2 Apparatus and method for manufacturing thick-walled hollow wheels having an internal gear toothing
A method for manufacturing a hollow wheel equipped with an internal gear toothing, wherein a work-piece includes a tubular section with a longitudinal axis, by which the term radial utilized in the following is defined. By N≧2 stamping tools, of which each one during the implementation of the method is brought into a working position, the tool for producing the gear toothing is processed on the inside of the tubular section, wherein the work-piece carries out a rotating movement with a rotation speed varying in time around the mentioned longitudinal axis and at least one stamping tool in the working position carries out radially oscillating movements, which are synchronized with the mentioned rotating movement. The at least one stamping tool in the working position processes the work-piece repeatedly.
US09174289B2 Saw
A saw has a base assembly, a saw assembly pivotally mounted on the base assembly, a motor mounted within the saw assembly, and a drive spindle rotatably driven by the motor via a drive mechanism. The drive mechanism has a rotatable output shaft, a first drive wheel mounted on the output shaft, a rotatable intermediate shaft, a first driven wheel mounted on the intermediate shaft, a first drive belt wrapped around the first drive wheel and first driven wheel for transfer rotary motion of the output shaft to the intermediate shaft, a second drive wheel mounted on the intermediate shaft, a second driven wheel mounted on the drive spindle, and a second drive belt wrapped around the second drive wheel and second driven wheel for transferring rotary motion of the intermediate shaft to the drive spindle.
US09174288B2 Slidable miter saw with guiding mechanism
A miter saw including: a base section; a saw blade; a cutting section; a support section; and a guiding mechanism. The support section includes a pivot support portion and a slide support portion. The pivot support portion supports the cutting section such that the cutting section is pivotally moved toward and away from the base section. The slide support portion slidably supports the pivot support portion to move the cutting section in a sliding direction that is in parallel with an upper surface of the base section and orthogonal to an axial direction of a rotational axis of the saw blade. The guiding mechanism is configured to guide a movement of the cutting section in the sliding direction in accordance with a pivotal movement of the cutting section toward the base section. The guiding mechanism is provided in association with the cutting section and the slide support portion.
US09174280B2 Mold, a device for processing the same, and a replica made therefrom
The present invention is directed to a mold. The present invention is also directed to a device for processing the same, and a replica made therefrom. A device for processing the mold comprises a cutting unit carving a surface of the mold; a housing accommodating the cutting unit and having an aperture through which a portion of the cutting unit protrudes; at least one piezo-electric element disposed between the cutting unit and the housing; and a signal generator applying an electrical signal to the piezoelectric element. The mold comprises a plurality of linear peaks and grooves that are formed on a surface of the mold, wherein both or one of the peaks and grooves have random or periodic meandering-shape. A replica manufactured by the mold comprises a plurality of linear crests and valleys that are formed on a surface of the replica, wherein both or one of the crests and valleys have random or periodic meandering-shape.
US09174279B2 Indexable cutting insert and cutting tool therefor
A cutting tool assembly includes a cutting tool and an indexable cutting insert having an insert index axis. The cutting insert includes parallel insert first and second sides connected by an insert peripheral surface that extends peripherally around the cutting insert. At least one clamping hole opens out to one or both of the insert first and second sides, and at least a portion of the clamping hole is in a clamping region of the cutting insert. The insert peripheral surface includes cutting edges that are spaced-apart and extend from the insert first side to the insert second side. Along a width direction, which is perpendicular to the insert first and second sides, each of the cutting edges is wider than the cutting insert, at least at the cutting region of the cutting insert.
US09174278B2 Substantially cylindrical powder compact and die assembly for compacting powder
The cross-sectional shape of a main part except for both end portions is generally divided into a lower arc surface extending along a base circle and an upper arc surface of which a top portion corresponds to the base circle. Side edge portions extending inward from the base circle are formed on both side surfaces of the upper arc surface. Curved edge portions which concavely curves upward from the side edge portions to end surfaces and continues to the end surfaces and chamfer portions extending from the end surfaces to the side surfaces which planes the edges and curves so that width thereof gradually narrows, are formed on both ends in a longitudinal direction.
US09174277B2 Ladle shroud for liquid metal casting installation
A ladle shroud for casting liquid metal contains a canal along which the metal can pass, extending essentially along an axis, and a metallic jacket positioned at an end portion of the shroud that corresponds to an end of the canal, characterized in that the jacket comprises at least a belt of a thickness greater than or equal to 10 mm, preferably of 14 mm, and in that the shroud comprises means of attachment to driving means, the attachment means being formed on the jacket, notably on the belt thereof.
US09174275B2 Method for manufacturing a metal-ceramic composite structure and metal-ceramic composite structure
A method for manufacturing a metal-ceramic composite structure for high temperature exposure is provided, whereby the composite structure includes a base metal structure or component, which is on at least one side covered and permanently joined with one or more ceramic tiles. The method may include the steps of: manufacturing green bodies with cavities and sintering the green bodies to receive ceramic tiles into cavities; arranging the ceramic tiles in a cast mould; pouring liquid metal into the cast mould to substantially fill the cavities; creating an intermediate metal layer; and solidifying the liquid metal to permanently join the ceramic tiles and the intermediate metal layer.
US09174272B2 Twin roll strip casting method
There is provided a strip casting method using a twin roll strip casting process in which molten steel is supplied through an injection nozzle to a region between twin rolls rotating in opposite directions to produce a strip having a predetermined thickness and a high degree of edge quality. The twin roll strip casting method includes: performing the casting process by setting a casting thickness to have a minimal value during an early stage of the casting process in which edge bulging occurs; and performing the casting process by increasing the casting thickness to a maximum value after the molten steel reaches a pre-set target temperature as the casting process proceeds.
US09174269B2 Tool for connecting and disconnecting conveying chain and method
A tool is provided for connecting and disconnecting links of a conveyor chain. The tool includes a base, a chain guide plate mounted on the base for supporting a length of conveyor chain in a fixed position relative to the base, and a backup block carried on the base. A pin extraction/insertion block is positioned on the base with the chain guide plate positioned between the backup block and the pin extraction/insertion block. A ram is carried on the pin extraction/insertion block for extracting a pin from a position in aligned holes in adjacent links while the chain is held in its fixed position, and an insertion rod is carried on the pin extraction/insertion block for inserting a pin in aligned holes in adjacent links.
US09174263B2 Tool and shell using induction heating
A component forming tool for forming a component from a blank includes a die forming shell having a first shell portion disposed at a first set of support elements and a second shell portion disposed at a second set of support elements. A first fluid line has a plurality of first fluid discharge ports at or near the first shell portion. A second fluid line has a plurality of second fluid discharge ports at or near respective ones of the first fluid discharge ports that are located in between the support elements. The component forming tool provides pressurized fluid in the first and second fluid lines and the pressurized fluids are discharged from the respective first and second fluid discharge ports. The fluid discharged from the second fluid line mixes with the fluid discharged from the first fluid line to cool the first shell portion.
US09174259B2 Method and apparatus for sharp flanging and trimming sheet metal panels
A method and apparatus for forming flanges on a panel. The flanges may be weld flanges or hem flanges. The flanges stretch to reduce spring back and may be trimmed. The trimming operation is performed after the flange area is formed on the panel.
US09174255B2 Energy-saving rolling mill train and energy-saving process for operating a combined casting and rolling station
In a rolling mill train (2; 30; 56) for processing rolling stock (4, 32), at least three rolling stands (10) are directly adjacent in the rolling direction and are driven by electric motors (20) having superconducting windings. It is thereby possible to keep the distances between the rolling stands smaller than with conventional electric drives, thus reducing energy losses during the rolling process. A combined casting and rolling station (40), which is equipped with such an electric motor (20) in the rolling stands, is configured and/or operated efficiently in terms of the required heating power.
US09174252B2 Device for clearing pipe blockage
A device for clearing pipe blockage includes: pumping means (A) for compressing air by pumping and having an outlet (18) for discharging compressed air out; and an inflatable balloon mounted at the outlet and expanding by air discharged through the outlet. The outlet is a one-way valve, and a cylindrical guide member (24) is formed to surround the outside of the inflatable balloon, guides the inflatable balloon to move forward inside a pipe when a front end part of the guide member is inserted into the pipe, and is made of flexible material. A presser which cleans the inner surface of the pipe while moving in a state where it gets in contact with the inner surface of the pipe is mounted at a front end of the inflatable balloon, and the blocked pipe is cleared by shock pressure by movement of the pumping unit and a change in pressure by expansion of the inflatable balloon by the compressed air.
US09174250B2 Method and apparatus for cleaning organic deposition materials
A method of cleaning off organic deposition material accumulated on a mask includes forming an organic deposition material pattern on a substrate using the mask, which includes a plurality of slots, in a deposition chamber including a deposition source; transporting the mask to a stock chamber that is maintained at a vacuum and adjacent to the deposition chamber; and partially cleaning off the organic deposition material accumulated along the boundaries of the slots of the mask in the stock chamber. A system to clean off an organic deposition material accumulated on a mask having a plurality of slots, includes a deposition chamber including a deposition source; and a stock chamber that is maintained at substantially the same vacuum as the deposition chamber and includes a cleaning device that cleans off the organic deposition material accumulated on the mask.
US09174248B2 Device for cleaning a hearing aid
The device for cleaning at least one medical hearing unit includes an earpiece, and a space for receiving the earpiece, the space having at least one seat receiving the earpiece and an orifice with a cavity underneath. There is a circulator for a liquid within the space to contact the earpiece. The cavity includes an outlet for flow or aspiration of liquid, an opening opposite, and, below each orifice, a directing device to guide the liquid towards and under each orifice, as far as the outlet, in such a way that liquid flows across the earpiece.
US09174245B2 System for the automatic selective separation of rotten citrus fruits
The invention relates to system conceived and designed to identify pieces of fruit, especially citrus fruits, affected by any amount of rot and to determine the automatic expulsion of these pieces from the conveyor moving them through the installation. The system comprises illuminating the fruits with UV-A band light in a computer vision unit, and capturing images of the illuminated fruits by means of a camera to send them to a general control member in order to detect fluorescences associated to the rot effect. The identified fruit is automatically expelled from the conveyor in an expulsion unit, the position of the defective fruit being determined with the aid of an encoder associated to the conveyor. The general control member is a PC type computer, equipped with specific application software.
US09174242B2 Zig-zag classifier and method for classifying for separating material to be separated
A zig-zag classifier for separating material to be separated, for example, plastic flakes, including two zig-zag-shaped plates which are arranged oppositely vertical to each other such that a channel is formed between them, where a central vertically disposed zig-zag-shaped separation plate between the two zig-zag-shaped plates is arranged such that the channel is divided into two parallel classifier channels having substantially the same width. Also, a method for separating material to be separated, for example, plastic flakes, using the zig-zag classifier disclosed herein.
US09174241B2 Screen comprising a plurality of stacked decks and means for vertically separating the decks from one another
A screen including a plurality of decks vertically stacked above one another, at least one of the decks bearing at least one sieve, the screen including means for vertically separating the decks from one another, suitable for selectively adjusting a vertical distance between each deck of the plurality of decks and at least one other deck of the plurality of decks.
US09174238B2 Particles having permanent dipole moment, films including the particles, and methods of preparing the films
A particle has a permanent dipole moment, a film includes the particle, and a method of forming the film includes aligning the particle on a surface. The particle has a permanent dipole moment and includes heterogeneous materials, wherein a positive pole is located in a first material and a negative pole is located in a second material different from the first material. The method includes aligning a particle such that the particle has one dipole moment direction. The film includes the aligned particles.
US09174237B2 Pressure sensitive adhesive article
Disclosed herein is an article including a substrate, a first layer adjacent the substrate, the first layer having a silicone-containing pressure sensitive adhesive and a thickness of less than about 5 um, and a second layer adjacent the first layer and opposite the substrate, the second layer having a pressure sensitive adhesive. The silicone-containing pressure sensitive adhesive can include a copolymer of a vinyl polymeric backbone having polysiloxane moieties grafted thereto.
US09174236B2 Rodless dispenser
A dispenser for viscous, extrudable materials uses a sprocket-driven push chain that is drawn from a chain magazine responsive to actuation of a user trigger. The sprocket for the chain is driven by a toothed wheel, which is driven by a first, ratcheting drive pawl, which is actuated by the trigger. A second ratcheting locking pawl prevents the toothed wheel and hence the chain sprocket from rotating backward when the trigger is released. A single “button” or actuator can be actuated by one hand of a user while the user's other hand grasps a chain retractor to pull an extended chain back to a starting position whereat the dispenser can be reloaded.
US09174235B2 Substrate treating apparatus using horizontal treatment cell arrangements with parallel treatment lines
A substrate treating apparatus includes a treating block including a plurality of cells arranged one over another. Each cell has treating units for treating substrates and a single main transport mechanism disposed in a transporting space for transporting the substrates to the treating units. The treating units include solution treating units and heat-treating units. The solution treating units are arranged at one side of the transporting space, the heat-treating units are arranged at the other side of the transporting space, and the main transport mechanism and the treating units are in substantially the same layout in plan view for the respective cells. The solution treating units are in substantially the same layout in side view for the respective cells, the heat-treating units are in substantially the same layout in side view for the respective cells, and treatments of the substrates carried out in the respective cells are the same.
US09174234B2 Method of applying a polyurethane adhesive to a substrate
A system and method for applying a two-part adhesive to a substrate includes a prime mover for providing an output torque, a first pump connected to the prime mover for receiving the output torque, the first pump having an inlet and an outlet, a second pump connected to the prime mover for receiving the output torque, the second pump having an inlet and an outlet, a first compound in communication with the inlet of the first pump, a second compound in communication with the inlet of the second pump, a first accumulator in communication with the outlet of the first pump, a second accumulator in communication with the outlet of the second pump, a first manifold in communication with the outlet of the first pump, and a second manifold in communication with the outlet of the second pump.
US09174227B2 Irrigation sprinkler nozzle
A nozzle for an irrigation sprinkler is provided, where the nozzle includes a sealing pad for reducing the distance relative to a seal of an irrigation device when the nozzle is in a retracted position to restrict the entry of grit and other debris into the irrigation device.
US09174226B2 Water spray gun
A water spray gun, including: a gun body, a valve switch, and a device for switching a spray pattern. The gun body includes: a water passage and double water hole. The valve switch includes: a button, a pressing piece including a unilaterally oblique plane, a rear plate including an inner guide rail, a rotating piece including a unilaterally oblique plane, a first spring, a front sealing ring, a switch rotating core, and a double sealing ring. The device for switching a spray pattern includes a water spray cap, a water spray plate, a decentered interface, a second spring, a wedge rotating piece for water diversion including a plurality of negative wedge blocks each including a negative wedge, a wedge push rod including a plurality of positive wedge blocks each including a positive wedge, a housing of a gun head, and a trigger.
US09174225B2 Filter
This filter is used to purify air by removing foreign matters such as liquid droplets contained in the air. A separation unit (23) is formed with a port block (13) and a separation cylinder (20), and the port block is formed with a primary port (11) and a secondary port (12). From the secondary port (12), the air purified by removing the foreign matters in a separation chamber (25) of the separation unit (23) is flowed out. A discharge pipe (37) for guiding the purified air to the secondary port (12) is disposed in a center portion of a swirl flow generating chamber (24). The foreign matters discharged from the discharging port (31) are collected in a collection container (27). In the collection container (27), a baffle plate 51 having a liquid guiding surface (50) is provided. A fin (52) is provided in an outer peripheral portion of the baffle plate (51), and the liquid guiding surface (50) positioned at a center portion of the baffle plate (51) is flat.
US09174224B2 Continuously operating centrifuge
A continuously operating centrifuge serves for centrifuging sugar massecuites. It has elements (20, 30, 40, 50) which rotate about a common axis (16). Furthermore, there is provided a drive unit (70), an outer housing incorporating a framework (10) having a base (11) and side walls (12) and vibration damping elements (82). An inner housing (80) is provided around the elements (20, 30, 40, 50) rotating about the common axis (16). The vibration damping elements (82) are arranged between the inner housing (80) and the base (11) of the framework (10) of the outer housing.
US09174223B2 Compact separation apparatus
A fluid separation apparatus for separating a fluid mixture including at least two fluids having different densities comprising a vessel having a vortex generation zone located within a fluid reservoir which includes a vortex generation wall which increases the rotational velocity of a fluid mixture flowing through the vortex generation zone and directs the fluid mixture from the fluid inlet toward the upper surface of the fluid reservoir. The vessel also includes a fluid inlet which extends into the vortex generation zone; a first fluid outlet through which the less dense fluid exits the vessel; and a second fluid outlet through which the denser fluid exits the vessel. The apparatus further comprises a gas bubble generator which introduces gas bubbles into at least a portion of the fluid mixture before the fluid mixture enters the vessel through the fluid inlet.
US09174222B2 Devices and method for enrichment and alteration of cells and other particles
The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.
US09174221B2 Method and apparatus for separation of mixture
Provided are a mixture separation method and a separation apparatus in which agglomeration of particles contained in the mixture is suppressed, energy required in distillation treatment of a supporting liquid is small in comparison with conventional methods, and particles that cannot be separated by conventional methods can be separated from a mixture containing the particles. The separation method and separation apparatus of the present invention separate, by type, a plurality of types of particles formed of mutually different materials by applying a magnetic field having a magnetic field gradient to the mixture containing the plurality of types of particles in the supporting liquid. Alternatively, the separation method and separation apparatus of the present invention separate a specific type of particle from such mixture. The supporting liquid is an organic solvent solution obtained by dissolving one or more types of paramagnetic compounds in an organic solvent. The plurality of types of particles includes particles of an inorganic salt, an organic acid salt, an inorganic oxide or a macromolecular compound. The organic solvent may be selected from the group consisting of alcohols, ethers, nitriles, ketones, esters, amides, sulfoxides, halomethanes and hydrocarbon solvents.
US09174209B2 Hydrogen storage composites and methods for manufacturing the same
Disclosed is a method of forming a hydrogen storage composite, including uniformly covering catalyst particles on the surface of a support to form a hybrid catalyst, and embedding the hybrid catalyst on the surface of a hydrogen storage material to form a hydrogen storage composite. Furthermore, the disclosed also provides a method for manufacturing the same.
US09174208B2 Fibrous catalyst
The present invention provides a method for preparing a fibrous catalyst for the treatment of a waste stream, the method comprising the steps of: (i) treating a fabric comprising polyacrylonitrile fibers with a hydrazine salt and a hydroxylamine salt in the presence of a base to provide a modified fabric; (ii) treating the modified fabric with a base; and (iii) treating the modified fabric with an aqueous solution comprising a sulfate salt of a first metal cation and a salt of a second metal cation, wherein the first metal cation is selected from an iron and nickel cation, and mixtures thereof, and wherein the second metal cation is selected from a lithium, sodium, potassium, rubidium, caesium, beryllium, magnesium, calcium, strontium, barium, zinc, cadmium, mercury, aluminum, gallium, indium, thallium, tin, lead, antimony and bismuth cation, and mixtures thereof.
US09174207B2 Process for producing compounds comprising nitrile functions
The present invention relates to a process for producing compounds comprising at least one nitrile function by hydrocyanation of a compound comprising at least one non-conjugated unsaturation.The invention proposes a process for producing compounds comprising at least one nitrile function by hydrocyanation of an organic compound comprising at least one non-conjugated unsaturation, comprising from 2 to 20 carbon atoms, by reaction with hydrogen cyanide in the presence of a catalytic system comprising a complex of nickel having the oxidation state of zero with at least one organophosphorus ligand chosen from the group comprising organophosphites, organophosphonites, organophosphinites and organosphosphines and a cocatalyst of the Lewis acid type.
US09174202B2 Catalyst that can be used in hydrotreatment, comprising metals of groups VIII and VIB, and preparation with acetic acid and dialkyl succinate C1-C4
A catalyst usable in hydrotreatment processes: an alumina-based amorphous support, phosphorus, a C1-C4 dialkyl succinate, acetic acid and a hydro-dehydrogenizing function of at least one group VIII element and at least one group VIB element, preferably made up of cobalt and molybdenum, a catalyst whose Raman spectrum comprises the most intense bands characteristic of the Keggin heteropolyanions (974 and/or 990 cm−1), C1-C4 dialkyl succinate and acetic acid (896 cm−1). Preferably, the dialkyl succinate concerned is dimethyl succinate and its main band is at 853 cm−1.
US09174200B2 Process for preparation of Ag—W oxide catalyst for the selective conversion of propylene to propylene oxide with molecular oxygen
The present invention provides a process for preparation of Ag—W oxide catalyst for the direct and selective conversion of propylene to propylene oxide. The process provides a direct single step selective vapor phase oxidation of propylene to propylene oxide using molecular oxygen over Ag—W oxide catalysts. The process provides propylene conversion of 10-50% and selectivity for propylene oxide up to 100%.
US09174193B2 Polymerisation reactor
Tubular reactor for use in polymerization reactions having a design pressure PR of 40-65 barg. The reactor includes a tube with a wall, and at least a portion of the tube is oriented vertically, with at least part of the vertical portion being surrounded by a concentric jacket for the passage of cooling fluid. The design pressure in barg of the jacket PJ is less than 0.0018·PR2.25.
US09174192B2 Tube bundle reactor for uncatalyzed or homogeneously catalyzed reactions
The invention relates to a tube bundle reactor with a flat feed hood. Alternatively, the release hood may also have a flat design. The flat design reduces the heat of reaction which arises in the hood in the case of reaction types which take place not only in the tube bundle (uncatalyzed reactions and reactions with homogeneously distributed catalyst). This greatly suppresses undesired reactions which already take place in the hood owing to accumulated heat, which achieves a higher selectivity in the case of thermally sensitive reactions. In addition, the thermal distribution within the hoods can be controlled precisely.The tube bundle reactor comprises a tube bundle which has a feed end which is connected to a feed hood of the tube bundle reactor, wherein the feed hood is configured in a flat design with a cross-sectional area at the feed end and an internal volume, and the ratio of internal volume to cross-sectional area is less than 0.35 m. The invention is further implemented by means of a process for operating a tube bundle reactor, comprising: introducing a reactant mixture into a tube bundle and converting at least a proportion of the reactant mixture within the tube bundle to a product. The introducing comprises: feeding the reactant mixture into an interior of a feed hood of the tube bundle reactor and passing the reactant mixture on into a feed end of the tube bundle in the form of a fluid stream. The fluid stream has a cross-sectional area on entry into the feed end, and the interior of the feed hood through which the fluid stream flows has an internal volume; where the ratio of internal volume to cross-sectional area is less than 0.35 m.
US09174190B2 Plasmonic assisted systems and methods for interior energy-activation from an exterior source
A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
US09174188B2 Lightweight, intrinsically safe ozone electrode
An electrode arrangement for an ozone generator includes a tubular dielectric which concentrically encloses a rod at a distance therefrom, and a filler material provided in an interstice between the tubular dielectric and the rod.
US09174185B2 System and method for preparing liquid fuels
Techniques, methods and systems for preparation liquid fuels from hydrocarbon and carbon dioxide are disclosed. The present invention can transform hydrocarbon and carbon dioxide generated from organic feed stocks or other industrial emissions into renewable engineered liquid fuels and store them in a cost-efficient way. The method of the present invention includes: supplying hydrocarbon and carbon dioxide to a heated area of a reaction chamber in controlled volumes; forming carbon monoxide by the energy provided by the heated area; transporting carbon monoxide and hydrogen to a reactor in controlled volumes; supplying additional hydrogen to the reactor; regulating the pressure in the reactor by adjusting the controlled volumes in order to achieve a predetermined object; forming the liquid fuel in the reactor according to the predetermined object; and, storing the liquid fuel in a storage device.
US09174182B2 Mixer with zero dead volume and method for mixing
A micro fluidics system includes a closed, expandable volume for mixing a fluid, and a flexible membrane for allowing mixing in the closed, expandable volume. The system further includes a surface having at least one channel for fluidically coupling a first side of the surface to the closed, expandable volume on a second side of the surface. The channel includes a first channel opening fluidically coupling the first side of the surface to the channel and a second channel opening fluidically coupling the channel to the closed, expandable volume. The expandable volume is defined by the flexible membrane closing the second channel opening when there is no fluid in the expandable volume.
US09174181B2 Disposable bioreactor for culturing cells in a nutrient medium
Disposable bioreactor for culturing cells in a nutrient medium, consisting of a reagent container which is sealable with a lid and which is capable of being subjected to a shaking process in a shaking device, where the reagent container is equipped with at least one web adjacent to the internal wall of the container, the web being arranged running vertically from the bottom upward, preferably in the shape of a helix.
US09174180B2 Agitator and a method of replacing a shaft seal of an agitator
Disclosed is an agitator having a drive unit coupled by means of a coupling to a first end of a drive shaft, a propeller attached to a second end of the drive shaft, the drive unit being attached to a mounting flange adapted for fastening the agitator to a wall of a mixing vessel, the agitator further comprising a support housing having at least a tubular support frame with a first end and a second end, the first end of the tubular support frame being attached to the mounting flange, the second end of the tubular support frame being provided with a support bearing for supporting the second end of the drive shaft, wherein a shaft seal is arranged at the first end of the tubular support frame and sealing means is arranged in connection with the second end of both the drive shaft and the tubular support frame.
US09174177B2 Floating dispenser
A floating dispenser having an external float or an internal float for supporting a cartridge or cartridges for floatingly delivering a dispersant or dispersants to a body of water with the floating dispenser having cartridges rotationally positionable with respect to one another to control the rate of dispensing while the dispenser floats in an upright condition with the floating dispenser changing its flotation orientation in response to consumption of the dispersant or dispersants in the cartridge or cartridges to thereby provide a visual alert to replace a spent cartridge with a fresh cartridge. In addition, the inventions described herein permit changing the dispensing nature of the system from a multiple dispensing system to a single dispensing system without changing the floating characteristics of the floating dispensers through replacement of a dispersant in one of the cartridges with an inert or ballast material that has no effect on the water characteristics.
US09174174B2 Separation membrane and method for producing the same
A separation membrane including a separation-functional layer is provided, wherein the separation-functional layer contains a polyvinylidene fluoride-type resin having a melt viscosity of 3,300 Pa·s or more, and also the separation-functional layer has a three-dimensional network structure. A separation membrane is provided having high virus removal performance, high pure water permeability, and high physical durability and high chemical strength, which can also be used in the field of water treatment.
US09174173B2 Chemical processing cell with nanostructured membranes
A chemical processing cell includes an upstream membrane and a downstream membrane. The upstream membrane generates a first reaction product. The downstream membrane converts the first reaction product to a second reaction product.
US09174172B2 Porous membrane, process for producing porous membrane, process for producing clarified liquid, and porous-membrane module
A porous membrane with the membrane wall constructed of a hydrophobic polymer and a hydrophilic polymer, wherein when the membrane wall is divided into 3 sections in the film thickness direction to form region “a” containing one wall surface A of the membrane wall, region “c” containing the other wall surface C and region “b” between region “a” and region “c”, the hydrophilic polymer content ratio Ca in region “a” is greater than the hydrophilic polymer content ratio Cc in region “c”, and the mean pore size of the wall surface C is larger than the mean pore size of the wall surface A.
US09174169B2 Mounting mat for exhaust gas treatment device
Disclosed is a mat or molded pre-form that may be used as a mounting mat to mount a fragile monolith within an outer housing of an exhaust gas treatment device, such as automotive catalytic converters and diesel particulate traps. The mat or pre-form may also be used as thermal insulation in the end cone regions of the exhaust gas treatment device. The mat and pre-form includes an inorganic microporous insulation component and a flexible fibrous material component. Exhaust gas treatment devices and methods for making exhaust gas treatment devices including the mat or pre-form are also disclosed.
US09174166B2 Method and device for treating ammonia in gasification system
Ammonia off-gas, which is separated and recovered by an ammonia recovery device from gasification gas produced in a gasification furnace in a two-column gasification system, is injected as reducing agent for denitration into an inlet of a cyclone for separation of bed material heated in a combustion furnace from combustion exhaust gas and for returning the bed material to the gasification furnace. The ammonia off-gas is contacted with the high-temperatured combustion exhaust gas to reduce and remove NOx through non-catalytic decomposition. Any excess of the ammonia off-gas is distributed for burning to primary air to the combustion furnace.
US09174165B1 Acidic gas removal using dry sorbent injection
A system and method for desulfurization or acidic gas removal from a hot flue gas is provided that uses a dry sorbent injection technology with downstream sorbent reproduction based on a dual-alkali process. As such, lime and flue gas carbon dioxide are used in a process to produce the dry sorbent, sodium bicarbonate.
US09174162B2 Machine tool mounted mist collector with filter clamp
A system for removing cooling liquid from a mist. The system includes an intake, where the intake is configured to receive the cooling mist and a baffle filter including a plurality of overlapping and offset layers of baffles, the baffle filter configured to collect and output cooling liquid from the cooling mist. The system also includes a mesh positioned vertically above the baffle and configured to drip cooling liquid collected thereon onto the baffle filter and an air filter, where the air filter is configured to remove a portion of pollutants from the demisted air. The system further includes a filter clamp configured to hold the air filter in place and an exhaust, where the exhaust is configured to output the demisted air.
US09174161B2 Process for removal of carbon dioxide from combustion gases
A device for purifying smoke gases comprising a cylindrical container with a gas inlet at its bottom region and a gas exit for purified gas in its top region, as well as an inlet for washing liquid and an exit for spent washing liquid, wherein the container internally does not include any current baffles so that the gas and liquid can rotate freely, and wherein the container internally has a stirring device of perforated plates, e.g. netting discs, for optimal mixing of gas and fluid. It is also disclosed a process for purifying such smoke gases, wherein such a purification device is used.
US09174160B2 Collapsible core, filter, and method
A collapsible winding core for a filter element is provided. A fluted filter media is wound about the collapsible winding core having a cylindrical shape. Subsequently, the collapsible winding core is collapsed into a generally flat shape to from the filter element having a racetrack shape.
US09174154B1 Reusable retainer assembly
A reusable retainer assembly for retaining a filter in an air handler includes a clip that may couple a filter to an air handler. An engaging portion of the clip may engage the air handler so the clip is retained on the air handler. A retaining portion of the clip may engage the filter so the clip retains the filter on the air handler.
US09174151B2 Porous medium screen
Certain aspects of the present invention are directed to a porous medium screen that can be disposed in a wellbore through a fluid-producing formation. The porous medium screen can include a porous medium and a retaining structure. The porous medium can be a material having one or more pores. The pores can be adapted to allow a fluid to flow through the porous medium and to prevent particles from flowing through the porous medium. The retaining structure can be adapted to retain the porous medium in a position circumferentially surrounding a section of a tubing string and to prevent expansion of the porous medium. The retaining structure can include a shroud and one or more stoppers. The shroud can be adapted to circumferentially surround the porous medium. Each stopper can be adapted to circumferentially surround the section of a tubing string at an edge of the porous medium.
US09174150B2 Float device
A float device for use in drawing liquids such as fuel from a tank or other reservoir is disclosed. The device comprises a float arranged for rising and falling with the level of liquid in the tank and a liquid pick-up duct, which comprises a flexible tube having its free end coupled to the float. The float is arranged for vertical movement within a filter or other member, which encloses the float and the flexible tube. The filter or other member is elongate and tubular in construction and comprises an open lower end.
US09174146B2 Closed gas buster separation system and method
A separation system including a horizontal separation vessel having a gas separation chamber defined by an upper wall of the separation vessel, a gas dome extending above the upper wall, a baffle plate disposed within the separation vessel, and a level of a lower surface of the baffle plate. The lower surface of the baffle plate is disposed below a level of an upper surface of a liquid weir disposed within the separation vessel. The upper surface of the liquid weir may set a liquid level within the separation vessel. The gas separation chamber may include a hydrostatic pressure seal zone between the level of the upper surface of the liquid weir and the level of the lower surface of the baffle plate. Liquid within the hydrostatic pressure seal zone may prevent a gas disposed within the gas separation chamber from escaping into a remainder of the separation vessel.
US09174140B2 Balloon inflator
A balloon inflator includes a tank containing a volume of pressurized gas and a regulator assembly removably secured to the tank for reducing the pressure of gas exiting the tank, the regulator assembly including a pressure regulator. A nozzle assembly is also provided and includes a valve for controlling dispensing of the pressurized gas. A flexible hose extends between the regulator assembly and the nozzle assembly, the hose being in fluid communication with the pressure regulator and the valve. The balloon inflator is small and lightweight, and therefore portable and concealable. The flexible nature of the hose allows for easy manipulation of the nozzle assembly, making use of the balloon inflator easier for performers.
US09174138B2 Playsets with molded shells
A play set includes a molded shell which includes at least two contoured panels and at least one hinge assembly is provided. The play set may optionally further include a figurine. The molded shell may be configured to have the appearance of a garment. Preferably, the molded shell provides a natural appearance of a garment when mounted onto the figurine.
US09174135B2 Storage medium having stored therein game program, game apparatus, game system, and game processing method
An input is acquired, and in accordance with the input, a sequence of game processing from beginning a predetermined game to obtaining a result of the game is performed. Then, a game image corresponding to the game processing from the beginning of the game to a state of the game still in progress is displayed on the portable display apparatus. A game image corresponding to at least part of the game processing from the beginning of the game to the state of the game still in progress is redisplayed on another display apparatus, and thereafter, a game image corresponding to the game processing until the obtaining of the result of the game is displayed on the other display apparatus.
US09174134B1 Peripheral device with haptic diminishment prevention component
A system is provided that modifies a haptic effect experienced at a user input element. The system receives a position of a trigger of a peripheral device, the peripheral device including a housing, a user input element, a haptic output device located within the housing and coupled to the user input element, and a haptic diminishment prevention component. The system further sends a haptic effect definition to the haptic output device in response to the received position of the user input element. The system further causes the haptic output device to output a force to the user input element of the peripheral device in response to the haptic effect definition. The system further causes the haptic diminishment prevention component to create a range that the user input element can move within in response to the output force when the user input element is in a maximum open position outside of the range, or a maximum closed position outside of the range.
US09174130B2 Video game with decoupled render and display rate
A server according to an embodiment provides online games that send game screens more suitably for the throughput of a user terminal. In accordance with one aspect, the server can execute a game program including: a game progress module for progressing a game; a generation module for generating, at first time intervals, frame information containing a plurality of drawing commands to be executed on a terminal device to render one frame of a game screen in accordance with progression of the game; a determination module for determining whether to send the generated frame information to the terminal device; a compression module for compressing the generated frame information; a sending module for sending to the terminal device the compressed frame information to be sent; and a request module for requesting drawing execution time information from the terminal device at second time intervals.
US09174121B2 Video game controller charging system having a docking structure
A video game controller charging system is provided. The video game controller charging system includes a base; at least one structure on the base for providing physical support to at least one video game controller while it is being charged; and at least one DC port on the base configured to couple to and provide DC power to a power input port of the at least one video game controller. The video game controller charging system may also include a current detector, a charging status indicator, at least one docking bay, and/or an AC-to-DC converter adapted to convert externally supplied power to the DC power provided to the power input port of at least one video game controller. The base of a charging station may include a recess having at least one electrical contact and a power input for connection to a power supply.
US09174119B2 Controller for providing inputs to control execution of a program when inputs are combined
A controller provides inputs to control execution of a program by combining controller input information and supplementary information utilizing a value of a first one of the controller input information or the supplementary input information as a modifying input to the game program for modifying a mapping or gearing of an input controlling a still active function activated in accordance with at least one of a second one of the controller input information or the supplementary input information or vice versa. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
US09174113B2 Adaptive ramp for accessing an enclosed ice surface
An ice access ramp assembly for accessing an ice surface includes a central bridge section and a pair of ramp sections. Each ramp section is pivotably mounted to the central bridge section for movement between a folded configuration and an extended configuration. The ramp sections and the central bridge section have surfaces formed of a low friction material. When the ramp assembly is extended, a first ramp section provides access from an outer floor and enables a sled skater to move up the first ramp section and onto the central bridge section. The sled skater can then move from the central bridge area onto the second ramp section, which provides access onto the ice surface. When not in use, the ramp assembly can be folded for storage and transport. The ramp assembly may include wheels that facilitate transport of the ice access ramp assembly over a floor or other surface.
US09174110B2 Robotic putting system
A robotic putting system includes a mechanism for actively and physically guiding a putter head along a determined preferred putting path. The golfer need only hold the putter and allow the robotic mechanism to guide the motion of the putter head. The system enables a golfer to develop and practice a feel for the preferred path/stroke.
US09174108B2 Free standing training bag with tripod base
A free standing training bag comprising a base with three legs and an upper body mounted atop the base, where the upper body has at least one striking surface suitable for use in martial arts training. Both the upper body and the base may be padded, allowing the free standing training bag to be used as a combat simulator.
US09174099B2 Golf club face
Golf club heads are described comprising a striking surface that includes a center zone that is free of scorelines and an impact zone having an impact zone area, Aiz, and having a plurality of scorelines in the impact zone having an impact zone scoreline area, Asliz, such that a ratio Asliz/Aiz is at least 0.10.
US09174095B2 Method and apparatus for training a golf swing
Apparatus and methods for using a plurality of golf balls to train a person to swing a golf club are described. In accordance with one aspect of the present invention, the apparatus includes a ramp, a golf ball holder and a trigger, which may be mechanical or electrical. The ramp conveys the plurality of golf balls, one at a time, from a first end of the ramp to a second end of the ramp. At least a portion of the ramp is angled downward from the first end to the second end. The holder contains the plurality of golf balls. It is arranged near the first end of the ramp to release one of the plurality of golf balls at a time onto the ramp. The holder further has an input. The trigger is connected to the input of the holder and arranged so that it can sense the golf swing, wherein when the trigger senses the golf swing, it triggers the input of the holder to cause the holder to release one of the plurality of golf balls into the ramp.
US09174093B2 Multi-piece solid golf ball
A multi-piece solid golf ball comprising a core, an envelope layer encasing the core, an intermediate layer encasing the envelope layer, and a cover which encases the intermediate layer and has formed on a surface thereof a plurality of dimples, wherein the core is made primarily of a rubber material and has a diameter of at least 31 mm, the envelope layer and intermediate layer are each made primarily of the same or different resin materials and the cover is made primarily of polyurethane; intermediate layer and cover have an optimized thickness relationship; the core, envelope layer, intermediate layer and cover have optimized hardness relationships; and the core surface and core center have a large hardness difference therebetween. The golf ball has excellent flight performance and controllability acceptable to professionals and other skilled golfers, while also having excellent durability to cracking upon repeated impact and excellent scuff resistance.
US09174086B1 Apparatus and method for delivery of assistive force to user moved weights
An apparatus providing an assist force to user moved weight of an existing un-motorized exercise or rehab machine or stand includes an assembly with operably connected motor and reel, a human-machine interface (HMI) that accepts input of variable parameters for assist control including entry of at least a user selected assist force and number of movement repetitions, a motor drive and a main digital controller connected with at least the motor, motor drive and HMI. The controller is programmed to provide a user selected non-zero assist force essentially only during parts of an exercise and a nominal static or drag force at other times. A cable has a first end securable to the reel and a second end configured to be coupled directly or indirectly with the weight to be moved by the user. The apparatus can be supplied in kit form.
US09174085B2 Exercise system and method
A method for providing cycling classes to remote users comprising providing information about available cycling classes that can be accessed via a digital communication network by a user at a remote location for display at the remote location, receiving from the user a selection of one of the available cycling classes for display at the remote location, and sending digital video and audio content comprising the selected cycling class from a server to a computer associated with a stationary bike at the remote location for display to the user on a display screen associated with the stationary bike. In various exemplary embodiments, the digital and audio content sent to the computer associated with the stationary bike is streamed for display to the user in substantially in real-time. In various exemplary embodiments, the digital and audio content sent to the computer associated with the stationary bike is archived content provided from a database.
US09174084B2 Automatic exercise segmentation and recognition
A physical activity monitoring device includes a sensor array with one or more sensors configured to measure physical activity attributes of a user. A controller automatically determines time intervals where the user is actively engaged in a physical activity based on the physical activity attributes. The controller also automatically determines a type of physical activity the user in actively engaged in during the determined time intervals based on the physical activity attributes. A reporter outputs information regarding the type of physical activity to the user.
US09174082B1 Abdominal exercise rolling pad
An exercise device designed to work and strengthen abdominal muscles while in a standing position comprises a center tube that forms the main axle of the device. The center tube extends completely through where it forms the left and right gripping handles. A pair of padded rollers is rotatingly supported upon the center tube and are pressed upon and then motioned downwardly and upwardly over a user's quadriceps in a reciprocating manner to exercise the abdominal muscles. A gap between the rollers is provided to allow clearance for the device as it is utilized.
US09174080B2 Modular exercise pole and anchoring system
A modular exercise pole and anchoring system is provided. The present invention relates to an exercise pole with multiple vertical and horizontal attachment points for connecting resistance training devices, the pole being attached to a base having a base post that accepts a plurality of plate-type weights for anchoring. The exercise pole and anchoring system have application to resistance training for fitness, among other uses, while the anchoring system alone has application to a number of uses where convenient, removable anchoring is desired.
US09174079B2 Muscle stimulation device
The invention relates to a muscle stimulation device comprising a handle bar with a first and a second end, a motor which is arranged in a cavity in the handle bar and is coupled by means of a motor shaft to at least one eccentric body in order to set the muscle stimulation device vibrating by an unbalance of the eccentric body. According to the invention the eccentric body/ies has/have a common center of mass, which is at a different distance from the first end of the handle bar than it is from the second end of the handle bar. The invention furthermore relates to an exchangeable head for such a muscle stimulation device.
US09174075B2 Explosion inhibiting portable fuel container and method of inhibiting explosions
A portable fuel container configured to prevent liquid fuel contained therein from being entirely emptied from the container. The amount of liquid fuel retained in the container can be sufficient to maintain a fuel-to-air ratio in the container at a fuel-rich level that prevents combustion within the container if the container were to be placed near an ignition source or if an ignition source were to somehow enter the container. The container can also include other safety features such as, for example, a flash suppressor located at the fill opening, an extra wide fill opening, and/or an easily controllable dispensing spout. When a flash suppressor is employed, the perforations in the flash suppressor can be configured to retain fuel therein after fuel has been dispensed from the container and the flash suppressor is no longer submerged in fuel.
US09174073B2 Energy absorber assembly and components thereof
An energy absorber assembly for use with a safety harness comprises a connector, a bracket assembly, a fastener, and an energy absorber. The connector is configured and arranged to operatively connect to the safety harness. The fastener operatively connects the bracket assembly and the connector, and the fastener releases the bracket assembly from the connector when subjected to a predetermined load. The energy absorber operatively connects the bracket assembly and the connector, and the energy absorber includes a first portion and a second portion that separate to absorb shock after the bracket assembly is released from the connector.
US09174071B2 Fall protection safety harness
Apparatus and associated methods relate to a fall-protection safety harness having padding structures located at harness pressure points, including dorsal and shoulder regions, the lumbar region, and leg regions. The padding structures may be constructed to provide air-flow parallel to a wearer's skin. Air may flow through wearer-webbing channels created by displacing a webbing via comfort pads. For example, the padding structures may be made by sandwiching foam pads between mesh fabric materials. The foam pads may be captured by the two mesh fabrics using circumferential stitching, for example. Circumferential stitching may permit the foam to retain its uncompressed form which may facilitate webbing displacement. Separate and symmetric pads may be located on both sides of a wearer's spine, both at the lumbar region and at the dorsal region of the back, permitting airflow between pads and along the wearer's spine.
US09174065B2 Energetic modulation of nerves
In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.
US09174059B2 Patient programmer with automated MRI compatibility verification for active implantable medical device
A system may include an active implantable medical device implantable in a body of a patient and a patient programmer for the AIMD. The patient programmer may be configured to obtain magnetic resonance imaging (MRI) compatibility information relating to compatibility of the AIMD with an MRI modality.
US09174058B2 Automatic selection of parameters of an exposure mode of an implantable medical device
An implantable medical device (IMD) automatically determines at least a portion of the parameters and, in some instances all of the parameters, of an exposure operating mode based on stored information regarding sensed physiological events or therapy provided over a predetermined period of time. The IMD may configure itself to operate in accordance with the automatically determined parameters of the exposure operating mode in response to detecting a disruptive energy field. Alternatively, the IMD may provide the automatically determined parameters of the exposure operating mode to a physician as suggested or recommended parameters for the exposure operating mode. In other instances, the automatically determined parameters may be compared to parameters received manually via telemetry and, if differences exist or occur, a physician or patient may be notified and/or the manual parameters may be overridden by the automatically determined parameters.
US09174055B2 Display of detected patient posture state
The disclosure provides a system that displays an indicator of patient posture state that changes according to posture state data. The posture state data may be transmitted from a medical device, for example, in or near real-time. In some examples, the disclosure relates to a method comprising receiving posture state data for a patient from a medical device; and presenting an indicator indicative of two or more of posture states based on the received posture state data, wherein each posture state of the two or more posture states is determined based on different detection criteria.
US09174051B2 Real time compliance voltage generation for an implantable stimulator
Circuitry for generating a compliance voltage (V+) for the current sources and/or sinks in an implantable stimulator device is disclosed. The improved compliance voltage generation circuitry adjusts V+ to an optimal value in real time, even during the provision of a stimulation current. The circuitry uses amplifiers to measure the voltage drop across an active PDACs (current sources) and/or NDAC (current sinks) The measured voltages are input to a V+ regulator, which compares the measured voltage drops across the DACs to optimal values, and which feeds an optimized value for V+ back to the DACs in real time to keep the voltage drop(s) at those optimal levels during the stimulation current for efficient DAC operation.
US09174049B2 Systems and methods for electrical stimulation of sphenopalatine ganglion and other branches of cranial nerves
Devices, systems and methods are disclosed for modulating cranial nerves, such as the sphenopalatine ganglion, to treat a medical condition of a patient, such as cluster headache. A stimulation device is advanced transnasally to a target site at or adjacent to the nasopharyngeal mucosa posterior to the middle turbinate. Electrical impulses are applied through one or more electrodes in the stimulation device to the target nerve sufficient to modulate the nerve and treat the medical condition.
US09174048B2 Positioning leads on patient model using a graphical user interface
A stimulation system, such as a spinal cord stimulation (SCS) system, for storing position information of an implanted medical lead implanted in a patient. A communication unit is configured to receive, from a first programmer, position data that indicates an actual position of the implanted medical lead with respect to a spinal column of the patient and an anatomically correct image of the spinal column. The communication unit is further configured to forward the position data, and to transmit both to a second programmer. The second programmer is then able to display a representation of the implanted medical lead on the anatomically correct image in an anatomically correct location and in an actual orientation based on the position data.
US09174047B2 Electrical feedthrough assembly
A device includes a hermetically sealed case with electronic circuitry housed within. One surface of the hermetically sealed case includes a metallic plate and a co-fired ceramic electrical feedthrough with a number of vias. The co-fired ceramic electrical feedthrough is hermetically joined to the metallic plate and a hybrid circuit is connected to the feedthrough.
US09174042B2 Wound healing electrode set
The technology disclosed herein pertains to wound healing electrodes and devices. The technology disclosed herein also pertains to electrode sets for electrically induced wound healing that can be adjusted to the wound size.
US09174039B2 Impact protection for implantable electric lead
A novel implantable electric lead arrangement is described for medical implant systems such as middle ear implants (MEI), cochlear implants (CI) and vestibular implants (VI). An electric lead contains parallel lead wires wound in an elongated helix about a central longitudinal axis. A lead core is fixed and enclosed within the wire helix for providing impact strain relief to the lead wires by resisting radial and/or axial deformation from external impact force.
US09174038B2 Neural electrode and method for fabricating the same
The invention relates to a neural electrode. It relates in particular to such an electrode which is able to withstand high mechanical forces, and to a method of fabrication of the same. The invention discloses an elastic neural electrode, having at least one planar metal layer which comprises conductive material and which is bilaterally covered by an protective elastomer layer, wherein, for reinforcement of the electrode, an additional reinforcement layer comprising reinforcement material is present between the outermost protective elastomer layers.
US09174034B2 Adaptable topical hyperbaric device
A wound treatment device includes a seal of variable size for attaching the device to various locations on a patient for treatment of wounds or lesions. The seal has a plurality of weakened areas which allow portions of the seal to be removed for increasing the size of the seal opening to accommodate wounds or lesions of different size.
US09174031B2 Device and method for deflation and removal of implantable and inflatable devices
Deflation devices including a catheter having a proximal opening at a proximal end and a distal opening at a distal end, and a coring member disposed within the catheter are disclosed herein. In one embodiment, the coring member comprises a handle disposed near the proximal end of the catheter, a cable, and a coring tip disposed near the distal end of the catheter. The distal end of the catheter can be configured to press against a wall of a balloon to create a substantially normalized surface of the balloon relative to a coring tip. A method for deflating and removing an implanted device, in accordance with another embodiment, can include pressing a distal end of a catheter against the wall of an inflated balloon of the device, and advancing the coring tip within the catheter beyond the distal end of the catheter and into the balloon.
US09174030B2 Weeping balloon catheter
Balloon catheters, and methods of treatment therewith, are provided including an inflatable first balloon at least partially enclosed by an expandable second balloon that has holes. The annular space between the first balloon and the second balloon is configured to promote delivery of the fluid evenly through holes in the second balloon to avoid problems of underloading and/or overloading. Preferably, the annular space is in communication with the holes, and the annular space is configured to receive and then to release and distribute the fluid via the holes in a substantially uniform manner such that even amounts of fluid are released in the distal and proximal holes. The first balloon may have various configurations including being tapered relative to the second balloon. The second balloon may also be tapered accordingly. The device may also include raised portions disposed in the annular space and configured to define channels having various configurations.
US09174028B2 Rough bio-absorbable strands for seed placement
A rough, bio-absorbable strand is provided. More specifically, a bio-absorbable strand having a central body and a rough or irregular outer surface capable of securing the placement of the strand inside a patient is provided. The strand has one or more radioactive seeds embedded in the central body of the strand. The rough outer surface of the strand may include one or more prongs, ridges, strips, grooves, or texture. Additionally, the strand may be capable of being dispensed from an implant needle.
US09174027B2 System for umbilical catheter
A medical catheter or tube clamp or support structure that is secured to an infant and holds a medical tube in place to prevent the tube from pistoning (axially moving within the infant relative to the entry point). In one embodiment, the medical tube claim comprises a catheter securing system that further includes a base that further includes at least one base member, a tube support member integrally formed with at least one base member that allows the tube to be inserted into an umbilical cord or stub in a relationally secure manner to prevent the tube from pistoning within an infant, and at one least channel for receiving a tube or catheter of a specified size and for securing the tube or catheter.
US09174026B1 Neonatal syringe retention device
A neonatal syringe retention device provides a means to retain a syringe in an elevated location inside of an incubator. The device comprises a suction cup removably attached to an interior wall surface of an incubator. The device also comprises a strap having a distal end comprising an aperture to hold the syringe body, and a proximal end having a plurality of apertures which adjust the overall length of the strap held from the suction cup.
US09174021B2 Catheter allowing variable dosing of an active agent
A drug eluting catheter includes an active agent, such as a drug or chemical substance, which is integrated with the catheter and allows variable dosing of the agent for elution to the patient's body. The catheter includes a dosing region and graduated markings or is associated with a measurement device that includes graduated markings that correspond to a range of dose of the active agent associated with the catheter. By removing or masking an undesired dosing region prior to administration, a user may vary the dosage to suit a patient's needs.
US09174018B2 Exhaust vent configuration
A respiratory interface device including a fluid coupling device having a main body and an exhalation plate having a plurality of vent holes, the exhalation plate being separate from and coupled to the main body. The present invention further relates to a fluid coupling device including an exhaust portion having a plurality of vent holes having a tapered shape. A set of the vent holes has an incident angle that radiates and originates from a common point. The present invention also relates to an exhalation mechanism including a plurality of vent holes defined by a continuous straight inner wall extending from an interior surface to an exterior surface wherein an exterior circumference of the vent hole is offset with respect to an interior circumference.
US09174015B2 Managing an active strap system for a face mask
A method for managing a set of active straps for a positive airway pressure (PAP) mask including detecting a pressure value with a pressure sensor, analyzing the pressure value with a processor for identifying an adjustment of the set of active straps, and performing the identified adjustment with the set of active straps.
US09174014B2 Introducer guide
An introducer guide (19) for an intubation device (21) having an open channel adapted to releasably secure an introducer, and shaped such that advancement of an intubation tube (21) through which the introducer extends causes the introducer to be removed from the introducer guide (19).
US09174010B2 Sprayer, in particular for medical use
A sprayer includes a container of product to be sprayed, provided with a delivery opening for this product, and a spraying assembly. The spraying assembly is in fluid communication with the delivery opening and is securable onto the container by insertion about a mounting axis. The spraying assembly includes a sprayer body delimiting a proximal area conformed so as to be securable to the container, and includes a distal wall, transverse to the mounting axis, in which a spraying aperture is arranged, and a cap intended to be mounted on the sprayer body. The cap includes a wall transverse to the mounting axis, which is sufficiently rigid so as to bear, without substantial damaging, a force from 50 to 100 N necessary to secure the sprayer body to the container and thus to enable the transmission to the sprayer body of this force.
US09174004B2 Pen needle assembly outer cover having a breakaway flange
An outer needle cover for a pen needle assembly is provided with a breakaway flange. Prior to use, the flange is connected to a body of the outer cover. The flange has a reduced cross sectional thickness portion that facilitates separation of the flange from the outer cover, thereby reducing the outer diameter of the outer cover. The reduced outer diameter of the outer cover allows the outer cover to be received by a pen cap of an existing injector device.
US09174002B2 Method for storing and delivering a drug
A container closure delivery system that is suitable for lyophilized pharmaceutical injectable powder products is disclosed. The system comprises storage stable powder formulations and a container closure assembly design wherein the formulation can be filled and lyophilized with a standard fill finish equipment, and the formulations and lyophilization processes are optimized to produce a powder that readily dissolves upon contact with a diluent, thereby facilitating the direct injection of the lyophilized product without the need for a separate reconstitution/mixing/priming step.
US09174001B2 Device and method for discharging a reactive liquid
A device and method for dispensing a liquid with a gas includes an instrument having a cannula and a low-pressure tip. The low-pressure tip includes a tip housing that at least partially defines a high pressure chamber. A distal wall of the tip housing includes an aperture in fluid communication with the high pressure chamber. The low-pressure tip also includes a tube and a gas flow channel. The tube fluidly communicates liquid at a relatively low pressure from the cannula through the first aperture. The gas flow channel fluidly communicates gas from the cannula at a relatively high pressure and to the high pressure chamber for discharge from the aperture. The tube and aperture are adapted to dispense the liquid and the gas in order to create a low pressure zone distal of the tube to dispense droplets of the liquid.
US09173997B2 External drug pump
Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.
US09173996B2 Infusion set for a fluid pump
A medical device for delivery of a fluid to a patient from a line terminating in a tubing needle. The medical device includes a cannula assembly for coupling the fluid into a cannula that is inserted into the patient. The cannula assembly has a first locking element disposed in a fixed position with respect to the cannula. Coupling the line to the cannula assembly is an infusion flap. The infusion flap includes a second locking element for engaging the first locking element of the cannula assembly and a lift tab for disconnecting the infusion flap from the cannula assembly. Coupling of the first and second locking elements requires initial mating of the infusion flap and cannula assembly followed by locking through rotation of the infusion flap with respect to the cannula assembly.
US09173993B2 Fluid delivery device
A method and an apparatus for delivery of a therapeutic fluid to the body of a patient are provided. The apparatus includes a dispensing unit having a driving mechanism and a pumping mechanism for pumping the fluid to the body of the patient and a collapsible reservoir fillable with the therapeutic fluid for delivery thereof to the body of the patient.
US09173991B2 Device for drug delivery
Delivery of more than one therapeutic fluid as a means to control symptoms of a health conditions is disclosed. More than one therapeutic fluid may be dispensed from more than one reservoir and delivered to a user's body via one or more cannula that penetrate the skin. The therapeutic fluids may be delivered by action of one or more pumping mechanisms that may be controlled by a processor in a portable, ambulatory device. The therapeutic fluids may optionally be insulin and one or more of an amylin analog, pramlintide acetate and an exenatide, and the health condition may optionally be diabetes.
US09173989B2 Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood/use of a device comprising a carbohydrate immobilized on a solid substrate, said carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, for extracorporeal removal of said pathogenic microbe, inflammatory cell or inflammatory protein from mammalian blood/use of a carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, wherein said carbohydrate is immobilized on a solid substrate, in the preparation of a device for treatment of a condition caused or aggravated by said pathogenic microbe, inflammatory cell or inflammatory protein/and a method for treatment of a mammalian subject suffering from a condition caused or aggravated by a pathogenic microbe, an inflammatory cell or an inflammatory protein.
US09173988B2 Sensor clip assembly for an optical monitoring system
A sensor clip assembly for an optical blood monitoring system includes a circuit board with a microprocessor that is programmed with a ratiometric model to calculate hematocrit and/or oxygen saturation levels of a patient.
US09173987B2 Degassing module for a controlled compliant flow path
A degassing module for removal of air and other gases during operation of a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The degassing module has a flow-through first chamber that has a hydrophobic vent membrane that has an exterior and interior side forming a portion of the flow-through chamber. The hydrophobic vent membrane is positioned at a higher elevation on the flow-through chamber than a fluid outlet. Fluid flows through the flow-through chamber in a downward direction relative to the hydrophobic vent membrane. A flow-through chamber has a cross sectional area configured to provide for a downward flow velocity of the fluid to be less than the upward rise velocity of a smallest bubble to be removed from the fluid.
US09173985B2 Total artificial heart
A total artificial heart having a rotor with an impeller, wherein the rotor is mounted within a pump housing on a hollow shaft. The rotor is magnetically driven to produce rotary motion of the impeller for pumping blood. The motor is disposed within the pump housing such that axial translation within the housing acts as a shuttle valve to alternate flow between pulmonary and systemic circulation.
US09173984B2 Ventricular assist device for intraventricular placement
The present invention includes various devices and methods for ventricular assist. In one embodiment, the present invention is a ventricular assist device for intraventricular placement inside a heart of a mammalian subject, the device including a ring configured to be mounted adjacent an apex of the patient's heart; a rigid elongate member having a proximal and distal end; and a pump having a housing and an outflow cannula having a tip, the tip having a distal end projecting through an aortic valve of the subject's heart, wherein the ring and the pump are connected to the rigid elongate member remote from one another so that the rigid elongate member maintains the pump in position relative to the ring.
US09173971B2 Simple adhesive coacervates and methods of making and using thereof
Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are produced by (a) preparing a solution comprising (1) a polyelectrolyte, wherein the polyelectrolyte comprises a polyanion or polycation but not a combination thereof, the polyeletrolyte comprises at least one crosslinking group, and (2) a sufficient amount of a complimentary counterion to produce a simple adhesive coacervate; and (b) crosslinking the simple adhesive coacervate to produce the adhesive. The adhesives have numerous medical and non-medical applications.
US09173969B2 Biomaterial for wound healing
The present invention provides a biomaterial comprising a scaffold consisting of collagen, hyaluronic acid, and gelatin, which are cross-linked via ethyl-3-[3-dimethylaminopropyl]carbodiimide (EDC) between any two of collagen, hyaluronic acid, and gelatin. The present invention further provides a method for preparing the biomaterial and a method for enhancing wound healing with the biomaterial.
US09173967B1 System for and method of processing soft tissue and skin with fluids using temperature and pressure changes
A method of processing soft tissue and skin using supercritical fluids is disclosed. The method comprises placing the soft tissue or skin on a scaffold in a processing chamber, adding supercritical fluid to the processing chamber, and pulsing the supercritical fluid in the processing chamber. A processing system for processing soft tissue and skin using supercritical fluids in accordance with the present invention comprises a processing chamber for housing the soft tissue, a scaffold, a vat for storing a processing fluid, a pump, a heating element, and a flow path.
US09173963B2 Diagnostic and treatment for chronic and acute phase myeloid leukemia
Disclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of reducing proliferation or promoting differentiation of a cancer cell having reduced level of Numb or increased level of Msi. Further disclosed are methods of treating a mammalian subject having cancer and methods of assessing an agent for chemotherapeutic potential.
US09173960B2 Methods of treating cancer with low density lipoprotein-related protein 6 (LRP6)—half life extender constructs
The present invention relates to LRP6 constructs that bind to LRP6 receptor. The LRP6 constructs comprise at least one LRP6 binding moiety and a half-life extender molecule such that the LRP6 construct inhibit the Wnt signaling pathway without potentiation of the Wnt signal. The LRP6 constructs also have an increased half-life to provide more time for the therapeutic benefit.
US09173958B2 Antibody buffering of a ligand in vivo
Compositions and methods are provided in embodiments directed to maintaining a desired concentration range of one or more drugs in a subject, and in particular embodiments to maintaining a desired drug concentration in a body compartment in a subject, based on the surprising discovery that antibodies persist in solution in body compartments such that antibody-antigen equilibrium principles can counteract drug clearance mechanisms. One or more antibodies are selected that have a dissociation constant KD that is similar to the desired drug concentration, wherein KD is independent of the affinity of the drug for a specific drug target (receptor) in the subject.
US09173955B2 Multivalent meningococcal polysaccharide-protein conjugate vaccine
The present invention describes a combined vaccine that offers broad protection against meningococcal disease caused by the pathogenic bacteria Neisseria meningitidis. The vaccine is comprised of four distinct polysaccharide-protein conjugates that are formulated as a single dose of vaccine. Purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W-135, and Y are chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains in children as well as adults.
US09173950B2 Vitamin D-ghrelin conjugates
The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.
US09173945B2 Ophthalmological aqueous composition
The present invention provides an aqueous ophthalmic composition containing (A) a terpenoid, (B) zinc chloride, and (C) at least one member selected from the group consisting of cellulose-based polymeric compounds, vinyl-based polymeric compounds, polyethylene glycols and dextran. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes.
US09173938B2 Combination of a purine-based CDK inhibitor with a tyrosine kinase inhibitor and use thereof in the treatment of proliferative disorders
The present invention relates to combination comprising (i) an ErbB inhibitor; and (ii) a CDK inhibitor, or a pharmaceutically acceptable salt thereof, selected from: (a) roscovitine; (b) 3-{9-isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-2-methyl-pentan-2-ol; (c) 3-{9-isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-pentan-2-ol; and (d) (2R,3S-3-(6-((4,6-dimethylpyridin-3-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)pentan-2-ol.Further aspects of the invention relate to pharmaceutical products and pharmaceutical compositions comprising combinations according to the invention, and methods of treatment using the same.
US09173936B2 Phospholipid drug analogs
Provided in some embodiments are compositions comprising a compound having a structure according to Formula A or Formula B: or a pharmaceutically acceptable salt, tautomer or hydrate thereof, where X2 is a bond or linker, X3 is bond or —PO4—, and X1, R1, R2, R3, and n are described herein. Also provided in some embodiments are methods for making and using such compounds and compositions.
US09173930B2 Methods for detecting a mycobacterium tuberculosis infection
Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.
US09173927B2 Methods to reduce scarring
The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing solution compositions (referred to herein as “SR-CFS” compositions), methods of making such novel compositions and uses thereof.
US09173926B2 Use of beta-1,3 (4)-endoglucanohydrolase, beta-1,3 (4)-glucan, diatomaceous earth, mineral clay and glucomannan to augment immune function
A method for the augmentation of immune function is described. The invention comprises a combination of β-1,3 (4)-endoglucanohydrolase, β-1,3 (4)-glucan, diatomaceous earth, mineral clay and glucomannan, which is fed to or consumed by mammalian or avian species in amounts sufficient to augment immune function. The invention described may be admixed with feeds or foods, incorporated into pelleted feeds or foods or administered orally to mammalian and avian species.
US09173917B2 Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug
The present invention relates to compositions and methods for reducing oxidative stress in a cell, increasing glutathione levels in a cell, increasing L-cysteine levels in a cell and reducing hepatocytotoxicity by contacting a cell with a sulfhydryl protected glutathione prodrug or a sulfhydryl protected cysteine prodrug.
US09173916B2 Method of preparing a muscadine pomace extract
Muscadine grape extracts are disclosed that have antioxidant properties. The extracts are a mixture of extracts from bronze and purple muscadine grapes that unexpectedly increase the solubility of ellagic acid in the mixture. Solvent extracts are obtained in some examples by water extracting the pomaces of the grapes from which the juice has substantially been removed. Further surprising increases in ellagic acid solubility can also be obtained by adding an additional source of anthocyanins to the extract, for example by including in the composition an extract of whole purple muscadine grapes from which substantial amounts of the juice have not been removed. Other additional sources of anthocyanins include blueberries, blackberries and raspberries; the additional source of anthocyanins can be obtained from a fruit processing waste stream to increase the efficiency of the production process.
US09173910B2 Compositions of microbiota and methods related thereto
Methods and compositions are provided for treating weight related conditions and metabolic disorders by altering microbiota in a subject. One aspect provides methods and compositions to alter microbiota in a subject by administering to the subject a composition that includes a substantially purified microbiota from phyla such as Bacteroidetes, Proteobacteria, Firmicutes and Verrucomicrobia or orders such as Bacteroidales, Verrucomicrobiales, Clostridiales and Enterobacteriales or genera such as Alistipes, Clostridium, Escherichia, and Akkermansia. Another aspect includes a pharmaceutical composition for altering microbiota that includes a therapeutically effective amount of substantially purified microbiota and a pharmaceutically acceptable carrier. Yet another aspect includes methods for treating a disorder, such as obesity, in a subject in need of such treatment by changing relative abundance of microbiota in a gastrointestinal tract of the subject without or in addition to a surgical procedure.
US09173907B2 Method of prenatal administration of mammalian umbilical cord stem cells for the intrauterine treatment of sanfilippo syndrome
A method of treating a fetus or embryo suspected of having a congenital condition that involves an abnormal or missing protein, the method has the steps of a. providing a plurality of human umbilical cord blood in a form suitable for intravenous administration; a b. administering the human umbilical cord blood cells to a mother carrying a fetus of embryo suspected of having said congenital condition. Such congenital conditions include Sanfilippo's syndrome, Hunter's syndrome, Hurler's syndrome, Tay-Sachs disease, Gaucher's disease, von Gierke's disease, Pompes disease, Cori disease, Andersen disease, McArdle's disease, Hers disease, Tauri's disease or Type IX glycogen storage disease.
US09173904B2 Method of cell transplantation into a human recipient
Methods and compositions are provided for the identification and isolation of mammalian HLA-G+ MSC, HLA-E+ MSC, or HLA-G+/HLA-E+ MSC. The methods of the invention provide a means to obtain enriched HLA-G+ MSC, HLA-E+ MSC, or HLA-G+/HLA-E+ MSC populations.
US09173899B2 Method of preventing and treating autistic spectrum disorder
Method of treating autistic spectrum disorder includes administration to a person of a product, which contains stable water clusters, such as stable double helix water clusters, by taking the products by mouth, applying the products on a skin of the person, intaking the product by breathing, introducing the products intravenously, etc.
US09173896B2 RNAi-mediated inhibition of connexin 43 for treatment of IOP-related conditions
RNA interference is provided for inhibition of connexin 43 (Cx43) in intraocular pressure-related conditions, including ocular hypertension and glaucoma such as normal tension glaucoma and open angle glaucoma.
US09173892B2 Acadesine derivatives, products and compositions including same, therapeutic uses thereof, and methods for synthesizing same
Acadesine derivatives as a drug, as well as the derivatives for the treatment of cancer and in particular for the treatment of chronic myeloid leukemia are described. Also, product containing the derivatives and at least one second active ingredient as a combination product for simultaneous, separate or sequential administration, in the treatment of cancer, as well as a pharmaceutical composition containing the derivatives and a pharmaceutically acceptable carrier are described. Finally, a method for inhibiting the in vitro cell proliferation including the placement of an in vitro cell in contact with the derivatives and methods for synthesis of said derivatives and methods for synthesis of the derivatives are described.
US09173886B2 Antiviral compounds and methods of use thereof
The present invention is drawn to a pharmaceutical composition comprising the following compound: The compound and other azacycle derivatives can be used in method of treatments for retroviral infections, such as HIV.
US09173884B2 Inhibitors of phosphodiesterase 11 (PDE11)
The present intervention generally relates to compositions comprising a PDE11 inhibitor for increasing cortisol levels in a subject, or for increasing the production of cortisol from adenocortical cells in a subject. Aspects of the invention relate to the use of a PDE11 inhibitor in a method of treatment of low cortisol levels and/or adrenal insufficiency in a subject, or a method of treating a disease or disorders associated with adrenal insufficiency. Aspects of the invention relate to PDE11 inhibitors belonging to compounds of formula (I)-(VI), and their use alone or in combination with long-term corticosteroid treatment to elevate cortisol levels in a subject, and/or to treat adrenal insufficiency. Another aspect relates to kits comprising PDE11 inhibitors for administration to a subject, pharmaceutical compositions comprising compounds of formula (I)-(VI) for use in methods to increase cortisol levels and/or treat adrenal insufficiency, and their use as an adjuvant for treatment of cancer or other disorders such as psychiatric diseases where elevating cortisol levels would be beneficial to the subject.
US09173883B2 Ring-substituted N-pyridinyl amides as kinase inhibitors
The present invention provides a compound of formula (A): as described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula I, and pharmaceutical compositions comprising such compounds.
US09173882B2 Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
Polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
US09173869B2 Mediators of hedgehog signaling pathways, compositions and uses related thereto
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.
US09173860B2 S isomers of α-methyl hydrocinnamic acid for the treatment of blood disorders
The present intervention generally relates to compositions comprising S-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood disorders and blood deficiencies, as well as methods for treating blood disorders and/or blood deficiency in a subject by administering a composition comprising S-isomer of alpha-methyl-hydrocinnamic acid to the subject to ameliorate at least one symptom associated with the blood disorder. Another aspect relates to administration of an S-isomer of alpha-methyl-hydrocinnamic acid stimulate multi-lineage hematopoietic cell production in a subject, for example, increasing the numbers of circulating neutrophils, erythrocytes and platelets. Accordingly, one aspect of the present invention relates to administration of S-isomer of alpha-methyl-hydrocinnamic acid, e.g., by oral administration to a subject for the treatment of blood disorders, for example but not limited to, hemaglobinaphthy, thalassemia and aplastic anemia. In some embodiments, the oral pharmaceutical formulation comprising an S-isomer of -α-methyl-hydrocinnamic acid can be used to increase red blood cell proliferation, or increase the proliferation of hemoglobin-expressing cells in a subject in need thereof, e.g., a subject having a blood deficiency such as a subject undergone chemotherapy or radiation exposure or radiation therapy. In some embodiments, a formulation comprising an S-isomer of alpha-methyl-hydrocinnamic acid (ST7S) can be used to simulate myelopiesis or erythropoiesis in a subject in need thereof.
US09173859B2 Uses of DPP IV inhibitors
The specification describes the use of selected DPP IV inhibitors for the treatment of physiological functional disorders and for reducing the risk of the occurrence of such functional disorders in at-risk patient groups. In addition, the use of the above-mentioned DPP IV inhibitors in conjunction with other active substances is described, by means of which improved treatment outcomes can be achieved. These applications may be used to prepare corresponding medicaments.
US09173858B2 Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
The present technology relates the use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas, for example of infantile hemangiomas. The beta blocker may be a non-selective beta-blocker, for example propranolol. The present technology provides an alternative to the known compounds, e.g. corticosteroids, interferon or vincristine, generally used for the treatment of hemangiomas.
US09173856B2 Therapeutic regimen and methods for treating or ameliorating visual disorders associated with an endogenous retinoid deficiency
Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable composition comprising a synthetic retinal derivative according to the therapeutic regimen which leads to local recovery of visual functions such as visual fields, visual acuity and retinal sensitivity, among others.
US09173855B2 Patch
Disclosed is a patch which is a formulation including deposited clonidine crystals and provides stable transdermal absorbability even after storage at varying temperatures. The patch disclosed includes a backing and a medicated layer integrally superposed on one surface of the backing. The medicated layer contains: 5 to 30% by weight of clonidine including clonidine in a crystallized state; 25 to 90% by weight of a macromolecular base (A) having a viscosity-average molecular weight of 800,000 or larger; and 5 to 60% by weight of a liquid additive capable of dissolving the clonidine. The weight ratio of the liquid additive to the macromolecular base (A) [the liquid additive/the macromolecular base (A)] is 0.1 to 2.0.
US09173851B1 Delayed release cysteamine bead formulation, and methods of making and using same
An enteric-coated bead dosage form of cysteamine, and related methods of manufacture and use, are disclosed.
US09173849B2 Solid pharmaceutical composition
The present invention provides a solid preparation containing compound (I) or a salt thereof, a pH control agent and a calcium antagonist, which is superior in the dissolution property, stability and the like.
US09173848B2 Solid pharmaceutical fixed dose compositions comprising irbesartan and amlodipine, their preparation and their therapeutic application
The present invention is directed to solid stable pharmaceutical fixed dose compositions comprising irbesartan, amlodipine besilate and pharmaceutically acceptable excipients, to their preparation and to their therapeutic application.
US09173847B2 Tablet comprising a fibrate
Stable tablets and pharmaceutical compositions in particulate form comprising a fibrate, for example fenofibrate, dissolved or dispersed in an non-aqueous vehicle with improved bioavailability, thereby eliminating the food effect so that the tablet or composition can be administered to a patient irrespective of being in fed or fasted state.
US09173846B2 Solid pharmaceutical compositions and processes for their production
This invention provides novel solid pharmaceutical compositions and processes for the bulk production of said compositions. This invention also provides methods of using the pharmaceutical compositions in the treatment of cancer.
US09173843B2 Crystalline active ingredient microparticles, method for producing the same and use thereof in drugs
A method for producing highly crystalline and stable microparticles of an active substance with a very narrow size distribution. The microparticles being crystallized out of a suspension made of primary particles of the active substance, a solution of the active substance, a non-solvent for the active substance and inert formed pieces. The resulting microparticles hare are highly stable largely independent of the physiochemical properties of the active substance and can be especially suitable for fast release dosage forms of pharmaceuticals.
US09173842B2 Stable pharmaceutical composition comprising a hydrosoluble vinflunine salt
Stable pharmaceutical composition consisting of a hydrosoluble vinflunine salt and at least one diluent and one lubricant, said composition being in the form of a solid intended for oral administration. The hydrosoluble vinflunine salt is preferably Vinflunine ditartrate. The pharmaceutical composition is advantageously in the form of a capsule or tablet. The invention also concerns a method of treating cancer pathology comprising the oral administration of the pharmaceutical composition of the invention.
US09173839B2 Anionic lipids and lipid nano-structures and methods of producing and using same
Anionic non-phospholipids, as well as lipid nanostructures formed therefrom, are disclosed herein. Also disclosed are methods of producing and using same.
US09173837B2 Controllable release nasal system
Embodiments of devices and system for controllable nasal delivery of materials are described. Methods of use of such devices and system and software for controlling the operation of such devices and systems are also disclosed.
US09173836B2 Pharmaceutical preparations for treatments of diseases and disorders of the breast
Formulations for topical or local administration of drugs directly to the breast or chest to produce a regional or local effect with lower systemic drug levels than when an effective amount is administered systemically are disclosed herein. In a preferred embodiment, the drug is administered to the surface of the breast, areola, or directly to the nipple. The formulations provide increased patient comfort, increased bioavailability and relatively high blood levels in the region to be treated with a reduction of side effects compared to those administered systemically. The preferred formulations contain drugs in the form of micro or nanoparticles, which may be formed of drug alone or in combination with an excipient or carrier. The excipient or carrier may modify the release rates or enhance absorption into the affected area. The drug formulation may be in the form of a cream, lotion or foam.
US09173832B2 Pituitous silicone fluids
Fluid compositions are disclosed containing a branched organopolysiloxane and a carrier fluid. The branched organopolysiloxane is obtainable by reacting an organohydrogencyclosiloxane and an alkenyl terminated polydiorganosiloxane. The disclosed fluid compositions possess pituitous rheological properties.
US09173827B2 Use of chitosans to increase nail growth rate
The present invention is directed to the use of chitosan, a chitosan derivative or a physiologically acceptable salt thereof, to increase nail growth rate. The invention is further directed to the use of chitosans to accelerate nail growth rate during treatment of nail illnesses, nail dystrophy or other nail conditions, in order to shorten considerably the specific treatments of said nail illnesses, nail dystrophy or other nail conditions.
US09173819B2 Music pacifier
A music pacifier (100) includes a pacifier frame (101) and a nipple (102) which locates at the one side of the frame and a container (106) locates on the other side of the frame. Within the container (106), there is a music IC & power supply (108), an insulating house (109), and a vibrating transducer (110). The insulating house (109) made of soft material is used to insulate the vibration produced. The vibrating transducer (110) is used to convert the pre-stored music into vibration. It locates in the above-mentioned house and connects with the above-mentioned music IC. There is also a vibrating tongue (111) which is used to pass the vibration produced by the above-mentioned vibrating transducer to an infant's jaw, including a contacting part (114) of the above-mentioned vibrating transducer which locates in the above-mentioned house as well as a tongue (113) which protrudes from the above-mentioned house and extends into the above-mentioned nipple.
US09173817B2 In situ forming hemostatic foam implants
Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
US09173816B2 Closed system transfer device and automation system
A robotic intravenous automation system, including a robotically controlled holder configured to manipulate an intravenous (IV) bag and a closed system transfer device (CSTD). The controller includes a processor configured to control the holder. The IV bag includes a first fluid port and a second fluid port, and the CSTD includes a CSTD port, a spike adapter that is fluidically separated from the CSTD port, and a flexible member connecting the CSTD port to the spike adapter.
US09173812B2 Packaging for unit pharmaceutical products
The invention relates to a packaging for unit pharmaceutical products, comprising: a receiving element (3) having at least one cell (7) defining an inner space (9) configured so as to receive such a product (2) and an opening (9) to said space; an element (10) for covering said cell, fixed to said receiving element in the region of the opening and designed so as to be torn or removed in order to extract said product; and a repositionable temporary closing body (22) designed such that it occupies a determined initial position from which it can be removed and at least one temporary closing position wherein it is temporarily fixed by adhesion to said element around said opening to the space of said previously opened cell; said determined initial position being separate from said closing position and said temporary closing body having an at least partially pre-glued closing part (23).
US09173809B2 Shower arrangement
Shower apparatus comprises a shower head (1) for expelling fluid in use, means (2) for connecting the shower head (1) to a water supply (3), a pressurized air supply (4), and guidance means (5) for guiding air flow from the pressurized air supply (4) to the shower head (1).
US09173808B2 Air and water massage system for tubs
A gas and liquid massage system for a tub comprises jets. Each jet has a gas injector and a liquid injector. The jets concurrently inject liquid and gas. A liquid circuit feeds a flow of liquid to the liquid injectors. A gas circuit feeds a flow of gas to the gas injectors. A sequencer manifold in the gas circuit selectively closes the gas supply to some of the jets to intermittently inject gas with the injected liquid. A massage system controller operates the sequencer manifold in selectively closing the gas supply to some of the jets. A method for injecting fluids into the liquid of the tub is also provided.
US09173807B2 CPR display for monitor/defibrillator with assisted CPR
A CPR device includes a CPR meter which is placed on the sternum of a patient and against which chest compressions are applied during CPR. The chest compressions are sensed by the CPR meter and this information is supplied to a display device for the display of the progress of CPR. A graphical display is provided which graphically illustrates the progress of CPR during a current CPR interval in either elapsed time or chest compressions delivered, as compared with the total time of the CPR interval or the maximum number of chest compressions to be delivered. The display can be configured to display either elapsed time or chest compression count, and the total number of compressions to be applied and the total duration of the CPR interval can be selectively configured.
US09173805B2 Support for copulating couples and method of use
A support for copulating couples and method thereof including, in general, a pair of support blocks, each configured as a polygon and each having six sides, (four sides, top side and bottom side with five possible tops determined by right-hand, left-hand, full upright, or sloped orientation), wherein the top and/or bottom includes an elbow indent and at one side or more includes a contour for fingers that functions to support the body weight of the top partner during copulation.
US09173799B2 Urine disposal device
A urine disposal device for use with a urine detecting device that provides for smooth urination without compressing the wearer's urethra so that urination may be surely detected and voided urine may be quickly discharged out of the urine disposal devices. The urine disposal device has a front-back direction and includes a urination area having a first surface portion and a second surface portion cooperating to cover the penis of a wearer from the front-back direction and an opening through which the penis is inserted. The urination area has a urine collecting container provided in the second surface portion and the second surface portion lies on the side of the wearer's body.
US09173794B2 Deck-on-deck adjustable bed frame
This disclosure concerns an adjustable bed with a deck-on-deck appearance. A concealing assembly is attached to the center frame of an articulating bed, wherein the concealing assembly is situated below the mattress platform and conceals the base frame as the center frame moves along the base frame when the bed articulates. In other embodiments, such as for non-wall hugger beds where the center frame is stationary, a concealing assembly may still be used but will also be stationary.
US09173791B2 Lightweight absorbent transporter
A lightweight, portable transporter for carrying a person having anti-hypothermia structures and an absorbent body is provided. The transporter has a backing substrate, an absorbent body, a gripping device, and anti-hypothermia structures, such as material segments or covers that reduce loss of body heat of the person being carried on the transporter. A method of using the transporter is provided.
US09173787B2 Absorbent article
It is an object of the invention to provide an absorbent article that is resistant to twisting and flattening, and that is superior in terms of fluid absorption rate, fluid diffusibility, absorbed fluid retention volume and fluid retention. The absorbent article comprises a top sheet on the skin contact side, a back sheet on the non-skin contact side, and an absorbent body situated between the two sheets, wherein the absorbent body comprises a bulky absorbent sheet, and the bulky absorbent sheet comprises heat-expanding particles that are dispersed in the bulky absorbent sheet and have been expanded by heat.
US09173784B2 Disposable diaper having reduced absorbent core to backsheet gluing
The present disclosure generally relates to disposable diapers having absorbent cores comprising superabsorbent polymer particles which are immobilized by adhesive. The absorbent cores are attached to the backsheets of the disposable diapers in certain attachment zones to reduce see-through and the formation of tension lines on the backsheets.
US09173782B2 Coordinated apertured and embossed topsheet layer materials, and absorbent articles containing such
A topsheet layer material for use on an absorbent article includes a longitudinal direction, a transverse direction and a depth direction and comprises a planar sheet. The topsheet layer material includes visually and spatially coordinated embossed channels and apertures. The embossed channels are curvilinear indentations configured along either the longitudinal, the transverse direction, or a combination of longitudinal and transverse directions. The apertures are positioned along the topsheet layer material laterally adjacent to the channels such that at least a portion of the apertures have an overall shape configuration that is substantially similar or the same as at least a portion of the shape of the embossed channel. Such coordinated aperture configuration may also be generally concentric with or generally parallel to the embossed channels.
US09173776B2 Foam structure wound inserts for directional granulation
A wound treatment system comprises a wound-treatment apparatus and a wound dressing coupled to the apparatus. The wound dressing includes a foam structure wound insert having pores with a greater cross-sectional area when viewed from a first direction and a smaller cross-sectional area when viewed from an orthogonal direction. Methods for making such wound inserts may include compressing foam structure material having pores with a substantially uniform cross-sectional area. Methods for treating a wound using a wound insert.