Document Document Title
US08988028B2 Reverse rotation braking for a PM motor
A system includes a motor, an inverter bridge, a voltage detection circuit, and a controller. The motor has a stator and a rotor. The inverter bridge is configured to provide a voltage to the stator, and includes a first switch connected in a series-type relationship with a second switch, a first diode coupled across the first switch, and a second diode coupled across the second switch. The voltage detection circuit is configured to detect a back EMF voltage in the winding. The controller is configured to control the first switch and the second switch to drive the motor, and to receive an indication of the back EMF voltage in the winding from the voltage detection circuit. The controller is also configured to determine a fault has occurred, and to drive one of the first switch and the second switch when a fault has occurred.
US08988021B2 Control of a brushless motor
A method of controlling a brushless motor that includes rectifying an alternating voltage to provide a rectified voltage having a ripple of at least 50%, exciting a winding of the motor with the rectified voltage, and performing a first process or a second process in response to current in the winding exceeding a threshold that is proportional to the rectified voltage. The first process includes freewheeling the winding, while the second process includes continuing to excite the winding for an overrun period and freewheeling the winding at the end of the overrun period. Additionally, a control system that implements the method, and a motor system that incorporates the control system.
US08988015B2 Power tool having a non-linear trigger-speed profile
A power tool including a motor, an input unit such as a variable-speed trigger switch, and a controller is provided. The controller controls the speed of the motor as a function of the input level indicated by the electrical signal from the input unit. The function is a first expression within a first predetermined range of the input level and a second expression within a second predetermined range of the input level, where the second expression corresponds to a polynomial of a second degree or higher and is different from the first expression.
US08988010B2 LED driving device and lighting device
An LED driving device that performs a dimming operation of an LED module, the device includes: a dimming controller that receives the dimming instruction signal and generates a dimming signal; and a driving circuit that supplies an output current to the LED module based on the dimming signal generated by the dimming controller, wherein the driving circuit unit includes: a converter controller that generates a drive signal based on the dimming signal and outputs the drive signal to a first switching element; a first current setting circuit; and a second current setting circuit that is connected in parallel to the first current setting circuit, and wherein the dimming controller controls an operating state of the second current setting circuit to switch an adjustment range of the output current and a change characteristic of the output current in response to the dimming signal.
US08988006B2 Projector
A projector includes: a discharge lamp; a discharge lamp driving unit that drives the discharge lamp by supplying a driving power to the discharge lamp through supply of a driving current thereto; and a control unit that controls the discharge lamp driving unit based on plural operating modes in which maximum values of the driving power are different from one another, wherein the control unit switches the operating mode through a transition period and controls the discharge lamp driving unit so that an average value of a frequency of the driving current in the former half of the transition period becomes larger than an average value of a frequency of the driving current in the latter half of the transition period.
US08988002B2 Lighting power supply device and method for controlling holding current
A lighting power supply device receives a voltage converted from an alternating current to a direct current by a rectifying circuit rectifying the alternating current whose phase is controlled by a phase control type dimmer, and generates and outputs a direct current voltage/current to be supplied to a load. The lighting power supply device includes: a control circuit, and the control circuit gradually decreases a current drawn from the rectifying circuit from a predetermined current value set in advance, determines a current value immediately before detecting a malfunction of the phase control type dimmer as a drawn current value, and performs current control so as to maintain the determined current value.
US08988001B2 Lamp and illumination system and driving method thereof
A lamp and an illumination system and a driving method thereof are provided. The lamp includes a lighting unit, a conversion unit, and a driver. The conversion unit is capable of receiving an input pulse width modulation (PWM) signal and converting the input PWM signal into an output PWM signal, wherein a frequency of the input PWM signal and a frequency of the output PWM signal are different. The driver is coupled between the lighting unit and the conversion unit. The driver is capable of receiving the output PWM signal and generating a driving signal to drive the lighting unit according to the output PWM signal.
US08987996B2 Light emitting module
A light emitting diode module includes a main base board, a wireless communication module, multiple light emitting diodes, a power output control system and a control unit. The wireless communication module is used for receiving a control signal. The light emitting diodes are disposed on the main base board and include light emitting diodes having at least one color. The power output control system is electrically connected to the light emitting diodes. The power output control system adjusts an amount of current flowing through each light emitting diode to control the light emitting diodes to emit light by adjusting the amount of current. The control unit is electrically connected to the wireless communication module and the power output control system for controlling the power output control system to adjust the amount of current of each light emitting diode.
US08987990B2 Plasma jet spark plug and ignition system
A plasma jet spark plug having increased capacitive discharge current, and thus improved plasma generation efficiency. The plasma jet spark plug includes an insulating body having an axial hole, a center electrode, a metal shell, and a cavity portion formed by the inner peripheral surface of the insulating body and the leading end face of the center electrode. A conductive layer formed from a conductive material is provided on at least one portion of at least one of: (a) a surface on the insulating body outer peripheral surface opposed to the inner peripheral surface of the metal shell, the conductive layer electrically connected to a ground electrode; and (b) a surface on the insulating body inner peripheral surface opposed to the outer peripheral surface of the center electrode, the conductive layer electrically connected to the center electrode.
US08987987B2 Organic electroluminescent device
The invention provides an OLED device with improved light out-coupling, which can be manufactured easy and reliable at low costs, which comprises an electroluminescent layer stack (2, 3, 4) on top of a substrate (1), where the electroluminescent layer stack (2, 3, 4) comprises an organic light-emitting layer stack (3) with one or more organic layers sandwiched between a first electrode (2) facing towards the substrate (1) and a 10 second electrode (4), where the second electrode (4) comprises a layer stack of at least a transparent conductive protection layer (41) on top of the organic light-emitting layer stack (3), a transparent organic conductive buckling layer (42) on top of the protection layer (41) having a glass transition temperature lower than the lowest glass transition temperature of the organic layers within the organic light-emitting layer stack (3) and a stress inducing layer 15 (43) on top of the buckling layer (42) to introduce stress to the buckling layer (42). The invention further relates to a method to manufacture such OLED devices with heating the electroluminescent layer (2, 3, 4) stack to a temperature, which is above the glass transition temperature of the buckling layer (42) and below the lowest glass transition temperature of the organic layers within the organic light-emitting layer stack (3) for a time period sufficient 20 to obtain buckles (B) within the buckling layer (42).
US08987986B2 Fluorescent substance, light-emitting device and method for producing fluorescent substance
The fluorescent substance according to the present disclosure emits luminescence with a peak in the wavelength range of 500 to 600 nm under excitation by light with a peak in the wavelength range of 250 to 500 nm, and has an optical absorption coefficient α560nm of 4×10−5 or less at 560 nm. The substance is represented by the following formula (1): (M1-xCex)2yAlzSi10-zOuNw  (1). In the formula, M is a metal element selected from the group consisting of Ba, Sr, Ca, Mg, Li, Na and K; and x, y, z, u and w are variables satisfying the conditions of 0
US08987985B2 Method and apparatus for light emission utilizing an OLED with a microcavity
Provided is an OLED device and method of making the OLED device. According to an embodiment, the OLED device incorporates a microcavity structure including a dielectric mirror formed on a glass substrate, an anode formed above the dielectric mirror, an organic film layer formed above the anode, and a reflective electrode formed above the organic film layer such that the cavity is formed in the organic film layer by the dielectric mirror and the reflective electrode. The OLED device with microcavity structure can incorporate one or more phosphors deposited on an underside of the glass substrate such that light of additional wavelengths can be generated by the OLED device.
US08987979B2 Piezoelectric vibrating piece, piezoelectric vibrator, oscillator, electronic apparatus, and radio-controlled timepiece
A piezoelectric vibrating piece includes a pair of vibrating arm portions which are arranged with a center axis interposed therebetween, a base portion which is arranged between a pair of vibrating arm portions and fixed to the outside, and a pair of connecting portions which connect proximal end portions of a pair of vibrating arm portions and a proximal end portion of the base portion. The distance between distal end portions of the vibrating arm portions and the center axis is smaller than the distance between the proximal end portions of the vibrating arm portions and the center axis.
US08987976B2 Piezoelectric resonator having combined thickness and width vibrational modes
A method and apparatus for a piezoelectric resonator having combined thickness and width vibrational modes are disclosed. A piezoelectric resonator may include a piezoelectric substrate and a first electrode coupled to a first surface of the piezoelectric substrate. The piezoelectric resonator may further include a second electrode coupled to a second surface of the piezoelectric substrate, where the first surface and the second surface are substantially parallel and define a thickness dimension of the piezoelectric substrate. Furthermore, the thickness dimension and the width dimension of the piezoelectric substrate are configured to produce a resonance from a coherent combination of a thickness vibrational mode and a width vibrational mode when an excitation signal is applied to the electrodes.
US08987972B2 Vibrator in vibration type driving apparatus and manufacturing method thereof
A vibrator, which constitutes a vibrating device of a vibration-type driving apparatus in which the vibrating device is bonded to an electromechanical-energy-conversion element, has at least one projection portion thereon, and elliptic motion can arise at each projection portion by applying an alternating electric field to the electromechanical-energy-conversion element. A driven object moves by the elliptic motion when in contact with the projection portion in a direction intersecting with a width direction. The vibrator includes a base and the at least one projection portion, with each projection portion having at least two wall portions extending in a base out-of-plane direction, and a contact portion having a contact surface with the driven object. The contact surface connects the wall portions, and boundary portions between the base and the wall portions are provided such that displacement directions in a normal direction are the same.
US08987969B2 Stator and manufacturing method thereof
The invention has an object to provide a stator including coils that protrude less in the radial direction of the stator and can be made smaller in the radial direction of the stator, and a method of manufacturing the same. In the stator, the conductor having a rectangular cross section is formed in a continuous meandering fashion, the conductor including: a plurality of in-slot portions arranged inside a slot of the stator such as to be overlapped with one another in a circumferential direction of the stator with long sides of the rectangle being oriented along a radial direction of the stator; a plurality of circumferential portions arranged at a coil end such as to be overlapped with one another in the radial direction of the stator with short sides of the rectangle oriented along the radial direction of the stator; a bent portion connecting the in-slot portion and the circumferential portion; and a twisted portion formed in the bent portion, the bent portion including a first bend formed on a side of the circumferential portion and a second bend formed on a side of the in-slot portion.
US08987966B2 Electric motor
An electric motor has a wound stator and a permanent magnet rotor. The rotor includes a shaft, a hub fixed on the shaft, a plurality of rotor core segments and magnets fixed around the hub, and a pair of covers fixed to axial ends of the rotor core segments. The hub and covers are formed on the rotor core segments by inserting molding and one of the covers has openings to allow the magnets to be inserted into spaces formed between adjacent rotor core segments such that the rotor core segments and magnets are alternately arranged in a circumferential direction of the rotor.
US08987965B2 Rotor and permanent magnet rotating machine
A rotor adapted for a large permanent magnet rotating machine having high output and demagnetization resistance and the permanent magnet rotating machine are provided. The permanent rotating machine includes the rotor and a stator disposed with a clearance from an outer peripheral face of the rotor and formed by winding a winding wire through a stator core having two or more slots. The rotor includes one or more permanent magnets in each of two or more insertion holes, the insertion holes being formed in a circumferential direction in a rotor core. There is also provided the permanent magnet rotating machine including this rotor and a stator disposed with a clearance from an outer peripheral face of the rotor and formed by winding a winding wire through a stator core having two or more slots.
US08987962B2 Double-stator/double-rotor type motor and direct drive apparatus for washer using same
Provided are a double-stator/double-rotor type motor, and a direct drive apparatus for a washing machine using the double-stator/double-rotor type motor, in which a nonmagnetic material is provided between inner and outer stators so as to form dual magnetic circuits that are respectively separated for an inner rotor and an outer rotor, and a double stator is disposed between an inner rotor and an outer rotor so as to separably form a magnetic circuit with a shortened magnetic.
US08987960B2 Supporting and heat dissipating structure for motor having integrated driver
The present disclosure provides a supporting and heat dissipating structure. A driver is arranged on an inner surface of a heat sink. The heat sink has protrusions for heat dissipation. An axle hole and a fixing ring are formed at the center of the heat sink. An elastic ring is arranged around the fixing ring for connecting with a supporting frame. A tubular barrel is used for connecting the heat sink to a motor. A structure for easily and firmly supporting the motor and the driver can be obtained. The structure can also absorb vibration while the motor rotating.
US08987959B2 Split magnetic thrust bearing
A magnetic bearing thrust stator is provided including, a plurality of stator sectors. Each of the stator sectors includes a semi-circumferentially slotted stator portion including a plurality of semi-circumferential poles and a first coil portion shaped to fit substantially within the semi-circumferentially slotted stator portion.
US08987955B2 Electric motor and electric device including the same
A stator, a rotor, bearings, and conductive brackets are provided. The stator has a stator iron core having a winding wound thereon. The rotor has a rotating body that holds a permanent magnet in the circumferential direction so that the permanent magnet faces the stator, and a shaft that has the rotating body fastened thereto so as to penetrate through the center of the rotating body. Both of the bearing on the output shaft side and the bearing opposite the output shaft side journal the shaft. One of the brackets fixes the bearing on the output shaft side, and the other of the brackets fixes the bracket opposite the output shaft side. The brackets are electrically connected to each other, and a dielectric layer is formed between the shaft and the outer periphery of the rotating body.
US08987949B1 Linear regulator with multiple outputs and local feedback
A linear regulator includes a first drive voltage output to drive an analog load, a second drive voltage output to drive a digital load, and a third output to provide a clean source of current. Circuit elements that produce the respective drive voltages may be isolated from each other. In addition, local feedback may be included to compensate for wide swings in circuit loading conditions in the analog load and in the digital load.
US08987948B2 Bus bar assembly
A solid state contactor assembly includes at least one solid state switch electrically connected to a first bus bar via at least one conductive plate. The solid state switch controls a flow of current between the first bus bar and a second bus bar. A current sensor is formed along a cross section of one of the first or second bus bar such that the current sensor separates its associated bus bar into two separate bus bar portions, and such that a flow of current between the two separate bus bar portions passes through the current sensor. A switch control is operable to control the solid state switch. The switch control is in communication with the current sensor.
US08987939B2 Hybrid power system with variable speed genset
A hybrid power system is disclosed. The hybrid power system may include a primary power source configured to provide a primary power, and an energy storage device coupled to the primary power source, the energy storage device configured to store excess primary power provided by the primary power source. The hybrid power system may further include a variable speed genset, the variable speed genset including a secondary power source configured to operate at a variable rotor speed to provide a secondary power responsive to power requirements of a load. The hybrid power system may also include a central controller communicatively coupled to the primary power source, the energy storage device, and the variable speed genset, the central controller configured to control the primary power source, the energy storage device, and the variable speed genset based on the power requirements of the load.
US08987933B2 Power over one-pair Ethernet approach
A power over one-pair Ethernet approach. A data transformer is coupled to a single conductor pair using one or more direct current (DC) blocking elements that preserve an alternating current path. The data transformer enables a network device to transmit and receive data with a link partner device via the single conductor pair. Power transmission over the single conductor pair is enabled through the coupling of a power over Ethernet module to the single conductor pair using a diode that can be paired with a zener diode.
US08987932B2 Deep water hydro-electric power system
A deep-water power generation system includes an initially evacuated enclosure having walls of suitable strength or reinforcement for maintaining its structural integrity thereof in deep-water pressures; a power axle extending through the enclosure from a north pole to below a south pole of the enclosure; preferably concave blades of a turbine secured upon a support frame secured to the power axle in a latitudinal plane of the enclosure; and inlet ports within the enclosure positioned at the latitudinal plane of the blades of the turbine and receiving an inflow of ambient deep water against the blades, in which a couple effect of force from the fluid flow induces rotation of the blades and of the power axle secured to the frame. A thrust deck is rigidly secured, within the enclosure, to the power axle above the turbine and to a generator secured upon the thrust deck. At the south pole of the enclosure, water is expelled into a high-pressure injection well descending to a geological level of a saline aquifer or discharged from a water chamber at the south pole and into a main water body under pressure provided to a discharge chamber in excess of the ambient deep-water pressure.
US08987930B2 Wind farm and method for operating a wind farm
A method for operating a wind farm comprising several wind turbines that are connected to an internal grid of the wind farm is disclosed. In the method, during a mains failure the electrical consumers of the wind turbines are supplied with electrical energy by a mains replacement supply unit. Each electrical consumer of the wind turbines is assigned to one of at least two groups and according to the group assignment is always switched on by an operation control unit when required, or only switched on if there is a sufficient power reserve. The wind farm is designed to carry out the method.
US08987929B2 System and method for operating wind farm
Systems and methods for operating a wind farm are disclosed. The method includes detecting an operating condition of an upwind wind generator, the upwind wind generator located upstream of a downwind wind generator relative to a wind flow direction. The method further includes communicating a control signal to the downwind wind generator. The control signal is based on the operating condition. The method further includes beginning to adjust the downwind wind generator according to the control signal before the wind flow is experienced by the downwind wind generator.
US08987927B2 Construction machine
A charge and discharge control unit (41) sets an upper-limit charge and discharge electric power as an upper limit of electric power during charging and discharging of a electric storage device (11) based on temperature of the electric storage device (11) measured by a temperature measuring unit (21) and a state of charge of the electric storage device (11) specified by a charge state specifying unit (23). In the case where the operation state determined by an operation state determining unit (35) is a low-limit operation state, the charge and discharge control unit (41) sets the upper-limit charge and discharge electric power to be larger than that in the case where the operation state determined by the operation state determining unit (35) is a high-limit operation state.
US08987919B2 Built-in electronic component substrate and method for manufacturing the substrate
A built-in electronic component substrate includes a first substrate, an electronic component including side surfaces and mounted on the first substrate, a first resin provided on the first substrate and covering the side surfaces of the electronic component, a second substrate provided above the electronic component and the first resin and layered on the first substrate, a substrate connection member provided between the first and the second substrates and electrically connecting the first and the second substrates, a second resin filling in between the electronic component and the second substrate and in between the first resin and the second substrate, and a third resin filling in between the first and the second substrates and encapsulating the substrate connection member, the electronic component, the first resin, and the second resin.
US08987918B2 Interconnect structures with polymer core
Embodiments of the present disclosure are directed towards techniques and configurations of interconnect structures having a polymer core in integrated circuit (IC) package assemblies. In one embodiment, an apparatus includes a first die having a plurality of transistor devices disposed on an active side of the first die and a plurality of interconnect structures electrically coupled with the first die, wherein individual interconnect structures of the plurality of interconnect structures have a polymer core, and an electrically conductive material disposed on the polymer core, the electrically conductive material being configured to route electrical signals between the transistor devices of the first die and a second die. Other embodiments may be described and/or claimed.
US08987917B2 Semiconductor device having non-planar interface between a plug layer and a contact layer
A semiconductor device is provided, in which it becomes easy to reliably couple a plug conductive layer and a wiring layer located over the plug conductive layer to each other and falling of the wiring can be suppressed. The plug conductive layer contacts a source/drain region formed over a major surface of the semiconductor substrate. A contact conductive layer is formed so as to contact both the upper surface and the side surface of the plug conductive layer. Wiring layers are formed over the contact conductive layer so as to be electrically coupled to the contact conductive layer.
US08987915B1 Semiconductor structure and manufacturing method thereof
A method of manufacturing a semiconductor structure includes several operations. The several operations include placing a plurality of dies on a carrier; defining a first zone and a second zone in a top surface of the carrier; calculating a first coverage ratio in the first zone; calculating a second coverage ratio in the second zone; disposing a dummy block on a specified location of the top surface of the carrier if the difference between the first coverage ratio and the second coverage ratio is greater than a predetermined value; forming a molding compound on the carrier.
US08987910B2 Method for obtaining a palladium surface finish for copper wire bonding on printed circuit boards and IC-substrates
The present invention relates to a method of bonding a copper wire to a substrate, particularly a printed circuit board and an IC-substrate, possessing a layer assembly comprising a copper bonding portion and a palladium or palladium alloy layer and a substrate having a copper wire bonded to aforementioned layer assembly.
US08987909B2 Method of manufacturing electronic component
According to one embodiment, a lower wiring layer is formed by using a sidewall transfer process for forming a sidewall film having a closed loop along a sidewall of a sacrificed or dummy pattern and, after removing the sacrificed pattern to leave the sidewall film, selectively removing the base material with the sidewall film as a mask. One or more upper wiring layers are formed in an upper layer of the lower wiring layer via another layer using the sidewall transfer process. Etching for cutting each of the lower wiring layer and the upper wiring layers is collectively performed, whereby closed-loop cut is applied to the lower wiring layer and the upper wiring layers.
US08987901B2 Component built-in wiring board and manufacturing method of component built-in wiring board
Disclosed is a component built-in wiring board including: a first insulating layer on a second one having laminated at least two insulating layers; a semiconductor chip buried in the second insulating layer, having a terminal pad; a wiring pattern between the first and the second insulating layers, including a mounting land and having a roughened surface facing the second insulating layer; a conductive bump between the terminal pad and the mounting land; a resin between the semiconductor chip and both the first insulating layer and the wiring pattern; a second wiring pattern between the at least two insulating layers; and an interlayer connector between surfaces of the wiring pattern and the second wiring pattern to penetrate partly through the second insulating layer in a layered direction, made of a conductive composition, and having a shape with an axis along the layered direction and a diameter varying in an axial direction.
US08987894B2 Underfill process and materials for singulated heat spreader stiffener for thin core panel processing
A method of making a microelectronic package, and a microelectronic package made according to the method. The method includes: bonding and thermally coupling a plurality of IC dies to an IHS panel to yield a die-carrying IHS panel, and mounting the die-carrying IHS panel onto a substrate panel including a plurality of package substrates by mounting perimeter ribs of the IHS panel to a corresponding pattern of sealant on the substrate panel and by mounting each of the plurality of dies to a corresponding one of the plurality of package substrates to yield a combination including the die-carrying IHS panel mounted to the substrate panel. Other embodiments are also disclosed and claimed.
US08987893B1 Heat dissipating interposers
Embodiments of the present disclosure provide an apparatus that comprises a connection circuit situated within a substrate and configured to communicatively couple a first integrated circuit disposed adjacent to a top surface of the apparatus to a second integrated circuit disposed adjacent to a bottom surface of the apparatus. The apparatus further comprises one or more enclosed heat dissipation structures situated within the substrate and configured to convey heat away from the first and second integrated circuits.
US08987892B2 Method for creating a selective solder seal interface for an integrated circuit cooling system
A method for forming cooling channels in an interface for soldering to a semiconductor structure. The method includes: forming a metal seed layer on a surface of a substrate; patterning the metal seed layer into a patterned, plating seed layer covering portions of the substrate and exposing other portions of the substrate; using the patterned plating seed layer to form channels through the exposed portions of the substrate; and plating the patterned plating seed layer with solder. A heat exchanger having cooling channels therein is affixed to one surface of the interface and the semiconductor structure is soldered to an opposite surface of the interface. The cooling channels of the heat exchanger are aligned with the channels in the interface.
US08987889B2 Semiconductor package with integrated interference shielding and method of manufacture thereof
An integrated electromagnetic interference (EMI) shield for a semiconductor module package. The integrated EMI shield includes a plurality of wirebond springs electrically connected between a ground plane in the substrate of the package and a conductive layer printed on the top of the package mold compound. The wirebond springs have a defined shape that causes a spring effect to provide contact electrical connection between the tops of the wirebond springs and the conductive layer. The wirebond springs can be positioned anywhere in the module package, around all or some of the devices included in the package, to create a complete EMI shield around those devices.
US08987885B2 Packaged microdevices and methods for manufacturing packaged microdevices
Microdevices and methods for packaging microdevices. One embodiment of a packaged microdevice includes a substrate having a mounting area, contacts in the mounting area, and external connectors electrically coupled to corresponding contacts. The microdevice also includes a die located across from the mounting area and spaced apart from the substrate by a gap. The die has an integrated circuit and pads electrically coupled to the integrated circuit. The microdevice further includes first and second conductive elements in the gap that form interconnects between the contacts of the substrate and corresponding pads of the die. The first conductive elements are electrically connected to contacts on the substrate, and the second conductive elements are electrically coupled to corresponding pads of the die. The first conductive elements are attached to the second conductive elements at corresponding interfaces such that the interconnects connect the contacts of the substrate directly to corresponding pads on the die within the gap.
US08987883B2 Semiconductor package with multiple conductive clips
One exemplary disclosed embodiment comprises a high power semiconductor package configured as a buck converter having a control transistor and a sync transistor disposed on a common leadframe pad, a driver integrated circuit (IC) for driving the control and sync transistors, and conductive clips electrically coupling the top surfaces of the transistors to substrate pads such as leadframe pads. In this manner, the leadframe and the conductive clips provide efficient grounding or current conduction by direct mechanical connection and large surface area conduction, thereby enabling a package with significantly reduced electrical resistance, form factor, complexity, and cost when compared to conventional packaging methods using wirebonds for transistor interconnections.
US08987882B2 Semiconductor device
A semiconductor device is reduced in size. The semiconductor device includes a die pad, a plurality of leads arranged around the die pad, a memory chip and a power source IC chip mounted over the die pad, a logic chip mounted over the memory chip, a plurality of down bonding wires for connecting the semiconductor chip to the die pad, a plurality of lead wires for connecting the semiconductor chip to leads, and a plurality of inter-chip wires. Further, the logic chip is arranged at the central part of the die pad in a plan view, and the power source IC chip is arranged in a corner part region of the die pad in the plan view. This reduces the size of the QFN.
US08987881B2 Hybrid lead frame and ball grid array package
A semiconductor device includes a first substrate having opposing first and second main surfaces, a first die disposed on the first main surface of the first substrate, a first bond wire coupled to the first die, a first packaging material encapsulating the first die and the first bond wire, and a lead frame disposed on the first main surface of the first substrate and in electrical communication with the first bond wire. At least a portion of the lead frame extends outside of the packaging material. A top package includes first and second main surfaces and an electrical contact on the second main surface. The electrical contact is electrically connected to the lead frame and connects the top package to either the first die and/or external circuitry.
US08987880B2 Chip module and a method for manufacturing a chip module
In various embodiments, a chip module may include a first chip; and a leadframe with a first leadframe area and a second leadframe area, wherein the first leadframe area is electrically insulated from the second leadframe area; wherein the first chip is arranged at least partially on the first leadframe area and at least partially on the second leadframe area.
US08987879B2 Semiconductor device including a contact clip having protrusions and manufacturing thereof
A semiconductor device includes a leadframe with a die pad and a first lead, a semiconductor chip with a first electrode, and a contact clip with a first contact area and a second contact area. The semiconductor chip is placed over the die pad. The first contact area is placed over the first lead and the second contact area is placed over the first electrode of the semiconductor chip. A plurality of protrusions extends from each of the first and second contact areas and each of the protrusions has a height of at least 5 μm.
US08987877B2 Semiconductor device
A semiconductor device of the present invention comprises: an outer package; a first lead frame including a first relay lead, a first die pad with a power element mounted thereon, and a first external connection lead which has an end protruding from the outer package; and a second lead frame including a second relay lead, a second die pad with a control element mounted thereon, and a second external connection lead which has an end protruding from the outer package, wherein the first die pad and the second die pad or the first external connection lead and the second relay lead are joined to each other at a joint portion, and an end of the second relay lead extending from a joint portion with the first relay lead is located inside the outer package.
US08987876B2 Power overlay structure and method of making same
A power overlay (POL) structure includes a POL sub-module. The POL sub-module includes a dielectric layer and a semiconductor device having a top surface attached to the dielectric layer. The top surface of the semiconductor device has at least one contact pad formed thereon. The POL sub-module also includes a metal interconnect structure that extends through the dielectric layer and is electrically coupled to the at least one contact pad of the semiconductor device. A conducting shim is coupled to a bottom surface of the semiconductor device and a first side of a thermal interface is coupled to the conducting shim. A heat sink is coupled to a second side of the electrically insulating thermal interface.
US08987871B2 Cap for a microelectromechanical system device with electromagnetic shielding, and method of manufacture
A cap for a microelectromechanical system device includes a first layer of, e.g., Bismaleimide Triazine (BT) resin material in which a through-aperture is formed, laminated to a second layer of BT resin material that closes the aperture in the first layer, forming a cavity. The first and second layers are laminated with a thermosetting adhesive that is sufficiently thick to encapsulate particles that may remain from a routing operation for forming the apertures. The interior of the cavity, including exposed portions of the adhesive, and the exposed face of the first layer are coated with an electrically conductive paint. The cap is adhered to a substrate over the MEMS device using an electrically conductive adhesive, which couples the conductive paint layer to a ground plane of the substrate. The layer of conductive paint serves as a shield to prevent or reduce electromagnetic interference acting on the MEMS device.
US08987865B2 Memory device having an integrated two-terminal current limiting resistor
A resistor structure incorporated into a resistive switching memory cell or device to form memory devices with improved device performance and lifetime is provided. The resistor structure may be a two-terminal structure designed to reduce the maximum current flowing through a memory device. A method is also provided for making such memory device. The method includes depositing a resistor structure and depositing a variable resistance layer of a resistive switching memory cell of the memory device, where the resistor structure is disposed in series with the variable resistance layer to limit the switching current of the memory device. The incorporation of the resistor structure is very useful in obtaining desirable levels of device switching currents that meet the switching specification of various types of memory devices. The memory devices may be formed as part of a high-capacity nonvolatile memory integrated circuit, which can be used in various electronic devices.
US08987864B2 Array type chip resistor and method of manufacturing thereof
There is provided an array type chip resistor including: a chip body, four pairs of lower electrodes disposed on both sides of a lower surface of the chip body and formed so as to be extended to edges of the chip body, side electrodes formed so that the lower electrodes are extended to sides of the chip body, and a resistor interposed between the lower electrodes on the lower surface of the chip body and electrically connected to the lower electrode through a contact portion, wherein when a width of the side electrode is defined as d1, a distance between adjacent side electrodes is defined as d2, and a height of the side electrode is defined as h, in the case in which d1/d2 is 0.5 to 1.5, a value of h is 4,300/d1 μm or above and is 0.24d2+87.26 μm or less.
US08987861B2 Semiconductor device and method of manufacturing the same
Characteristics of a semiconductor device are improved. A semiconductor device has a laminated insulating film formed above a lower-layer inductor. This laminated insulating film includes a first polyimide film, and a second polyimide film formed on the first polyimide film and having a second step between the first polyimide film and the second polyimide film. An upper-layer inductor is formed on the laminated insulating film. Since such a laminated structure of the first and second polyimide films is adopted, the film thickness of the insulating film between the lower-layer and upper-layer inductors can be increased, so that withstand voltage can be improved. Further, the occurrence of a depression or peeling-off due to defective exposure can be reduced, and step disconnection of a Cu (copper) seed layer or a plating defect due to the step disconnection can also be reduced.
US08987860B2 Semiconductor device
A semiconductor device includes a substrate having a plurality of active regions defined by a device isolation region, a plurality of conductive patterns on the plurality of active regions, each of the conductive patterns having side walls, a conductive line that faces the side walls of the conductive patterns with an air spacer therebetween on the active regions, the conductive line extending in a first direction, and a first insulating film covering the side walls of the conductive patterns between the air spacer and the conductive pattern. A lower portion of the first insulating film that is near the substrate protrudes toward the air spacer.
US08987858B2 Method and system for transient voltage suppression
A transient voltage suppression (TVS) device and a method of forming the device are provided. The device includes a first layer of wide band gap semiconductor material formed of a first conductivity type material, a second layer of wide band gap semiconductor material formed of a second conductivity type material over at least a portion of the first layer and comprising an ion implanted material structure between 0.1 micrometers (μm) and 22.0 μm thick, the second layer operating using punch-through physics, and a third layer of wide band gap semiconductor material formed of the first conductivity type material over at least a portion of the second layer.
US08987856B2 Photodiode having N-type and intrinsic amorphous IGZO layers
A photodiode, a light sensor and a fabricating method thereof are disclosed. An n-type semiconductor layer and an intrinsic semiconductor layer of the photodiode respectively comprise n-type amorphous indium gallium zinc oxide (IGZO) and intrinsic IGZO. The oxygen content of the intrinsic amorphous IGZO is greater than the oxygen content of the n-type amorphous IGZO. A light sensor comprise the photodiode is also disclosed.
US08987849B2 Co/Ni multilayers with improved out-of-plane anisotropy for magnetic device applications
A MTJ for a spintronic device is disclosed and includes a thin seed layer that enhances perpendicular magnetic anisotropy (PMA) in an overlying laminated layer with a (Co/X)n or (CoX)n′ composition where n is from 2 to 30, X is one of V, Rh, Ir, Os, Ru, Au, Cr, Mo, Cu, Ti, Re, Mg, or Si, and CoX is a disordered alloy. The seed layer is preferably NiCr, NiFeCr, Hf, or a composite thereof with a thickness from 10 to 100 Angstroms. Furthermore, a magnetic layer such as CoFeB may be formed between the laminated layer and a tunnel barrier layer to serve as a transitional layer between a (111) laminate and (100) MgO tunnel barrier. The laminated layer may be used as a reference layer, dipole layer, or free layer in a MTJ. Annealing between 300° C. and 400° C. may be used to further enhance PMA in the laminated layer.
US08987846B2 Magnetic memory and manufacturing method thereof
According to one embodiment, a magnetic memory is disclosed. The magnetic memory includes a substrate, and a contact plug provided on the substrate. The contact plug includes a first contact plug, and a second contact plug provided on the first contact plug and having a smaller diameter than that of the first contact plug. The magnetic memory further includes a magnetoresistive element provided on the second contact plug. The diameter of the second contact plug is smaller than that of the magnetoresistive element.
US08987844B2 MEMS device and process
A MEMS capacitive transducer with increased robustness and resilience to acoustic shock. The transducer structure includes a flexible membrane supported between a first volume and a second volume, and at least one variable vent structure in communication with at least one of the first and second volumes. The variable vent structure includes at least one moveable portion which is moveable in response to a pressure differential across the moveable portion so as to vary the size of a flow path through the vent structure. The variable vent may be formed through the membrane and the moveable portion may be a part of the membrane, defined by one or more channels, that is deflectable away from the surface of the membrane. The variable vent is preferably closed in the normal range of pressure differentials but opens at high pressure differentials to provide more rapid equalization of the air volumes above and below the membrane.
US08987841B2 Backside stimulated sensor with background current manipulation
A CMOS (Complementary Metal Oxide Semiconductor) pixel for sensing at least one selected from a biological, chemical, ionic, electrical, mechanical and magnetic stimulus. The CMOS pixel includes a substrate including a backside, a source coupled with the substrate to generate a background current, and a detection element electrically coupled to measure the background current. The stimulus, which is to be provided to the backside, affects a measurable change in the background current.
US08987840B2 Edge-mounted sensor
Sensor packages and methods for making a sensor device package for side mounting on a circuit board. A sensor device(s) in a mechanical layer of silicon is sandwiched between first and second layers of glass to create a wafer. A first via(s) is created in the first or second layers to expose a predefined area of the mechanical layer of silicon. A second via(s) is created in the first or second layers. The least one second via has a depth dimension that is less than a depth dimension of the first via. A metallic trace is applied between the exposed area on the mechanical layer and a portion of the second via. The wafer is sliced such that the second via is separated into two sections, thereby creating a sensor die. The sensor die is then electrically and mechanically bonded to a circuit board at the sliced second via.
US08987838B2 Field-effect transistor
A field-effect transistor includes a plurality of unit elements which include a semiconductor layer having a first surface, a plurality of gate electrodes, drain electrodes, and source electrodes. Each of the plurality of gate electrodes is provided to define a drain electrode formation region which is surrounded by each of the plurality of gate electrodes. Each of the source electrodes is disposed in a source electrode formation region surrounded by the plurality of gate electrodes of the plurality of unit elements which are adjacent to each other. A source-gate distance between the each of the source electrodes and the each of the plurality of gate electrodes of the plurality of unit elements is shorter than a drain-gate distance between each of the drain electrodes and the each of the plurality of gate electrodes. The source electrode formation region is smaller than the drain electrode formation region.
US08987834B2 Methods of providing electrical isolation and semiconductor structures including same
Methods of isolating gates in a semiconductor structure. In one embodiment, isolation is achieved using a spacer material in combination with fins. In another embodiment, etch characteristics of various materials utilized in fabrication of the semiconductor structure are used to increase an effective gate length (“Leffective”) and a field gate oxide. Semiconductor structures formed by these methods are also disclosed.
US08987832B2 Nonvolatile memory including memory cell array having three-dimensional structure
A nonvolatile memory is provided which includes a plurality of channel layers and a plurality of insulation layers alternately stacked on a substrate in a direction perpendicular to the substrate, each of the plurality of channel layers including a plurality of channel films extending along a first direction on a plane parallel with the substrate; a plurality of conductive materials extending from a top of the channel layers and the insulation layers up to a portion adjacent to the substrate in a direction perpendicular to the substrate through areas among channel films of each channel layer; a plurality of information storage films provided between the channel films of the channel layers and the conductive materials; and a plurality of bit lines connected to the channel layers, respectively, wherein the conductive materials, the information storage films, and the channel films of the channel layers form a three-dimensional memory cell array, wherein the conductive materials form a plurality of groups, and wherein a distance between the groups is longer than a distance between conductive materials in each other.
US08987829B2 Semiconductor device
A semiconductor device may include a p-channel semiconductor active region and an n-channel semiconductor active region. An element isolation insulating layer electrically isolates the p-channel semiconductor active region from the n-channel semiconductor active region. An insulating layer made of a different material, being in contact with both ends, in its channel length direction, of the p-channel semiconductor active region applies a compression stress in the channel length direction to a channel of the p-channel semiconductor active region. The p-channel semiconductor active region is surrounded by the insulating layer, in the channel length direction, of the p-channel semiconductor active region and by the element isolation insulating layer, parallel to the channel length direction, of the p-channel semiconductor active region. The n-channel semiconductor active region is surrounded by the element isolation insulating layer.
US08987828B2 N-channel and P-channel end-to-end finFET cell architecture with relaxed gate pitch
A finFET block architecture uses end-to-end finFET blocks in which the fin lengths are at least twice the contact pitch, whereby there is enough space for interlayer connectors to be placed on the proximal end and the distal end of a given semiconductor fin, and on the gate element on the given semiconductor fin. A first set of semiconductor fins having a first conductivity type and a second set of semiconductor fins having a second conductivity type can be aligned end-to-end. Interlayer connectors can be aligned over corresponding semiconductor fins which connect to gate elements.
US08987825B2 Semiconductor device having a double deep well
A semiconductor device includes a substrate having a first type doping. The semiconductor device further includes a first deep well in the substrate, the first deep well having a second type doping. The semiconductor device further includes a second deep well in the substrate, the second deep well having the second type doping and being separated and above the first deep well. The semiconductor device further includes a first well over the second deep well, the first well having the first type doping and a gate structure over the first well.
US08987823B2 Method and structure for forming a localized SOI finFET
Methods and structures for forming a localized silicon-on-insulator (SOI) finFET are disclosed. Fins are formed on a bulk substrate. Nitride spacers protect the fin sidewalls. A shallow trench isolation region is deposited over the fins. An oxidation process causes oxygen to diffuse through the shallow trench isolation region and into the underlying silicon. The oxygen reacts with the silicon to form oxide, which provides electrical isolation for the fins. The shallow trench isolation region is in direct physical contact with the fins and/or the nitride spacers that are disposed on the fins. Structures comprising bulk-type fins, SOI-type fins, and planar regions are also disclosed.
US08987822B2 Thin film transistor, method for manufacturing the same, and semiconductor device
In a thin film transistor, an increase in off current or negative shift of the threshold voltage is prevented. In the thin film transistor, a buffer layer is provided between an oxide semiconductor layer and each of a source electrode layer and a drain electrode layer. The buffer layer includes a metal oxide layer which is an insulator or a semiconductor over a middle portion of the oxide semiconductor layer. The metal oxide layer functions as a protective layer for suppressing incorporation of impurities into the oxide semiconductor layer. Therefore, in the thin film transistor, an increase in off current or negative shift of the threshold voltage can be prevented.
US08987818B1 Integrated MOS power transistor with thin gate oxide and low gate charge
A split gate power transistor includes a laterally configured power MOSFET including a doped silicon substrate, a gate oxide layer formed on a surface of the substrate, and a split polysilicon layer formed over the gate oxide layer. The polysilicon layer is cut into two electrically isolated portions, a first portion forming a polysilicon gate positioned over a channel region of the substrate, and a second portion forming a polysilicon field plate formed over a portion of a transition region of the substrate. The two polysilicon portions are separated by a gap. A lightly doped region is implanted in the substrate below the gap, thereby forming a bridge having the same doping type as the substrate body. The field plate also extends over a field oxide filled trench formed in the substrate. The field plate is electrically coupled to a source of the split gate power transistor.
US08987813B2 High voltage metal-oxide-semiconductor transistor device
A high voltage metal-oxide-semiconductor transistor device includes a substrate, at least an isolation structure formed in the substrate, a gate formed on the substrate, and a source region and a drain region formed in the substrate at respective sides of the gate. The isolation structure further includes a recess. The gate includes a first gate portion formed on a surface of the substrate and a second gate portion downwardly extending from the first gate portion and formed in the recess.
US08987812B2 Semiconductor device and semiconductor device manufacturing method
The invention provides an ultra-low-on-resistance, excellent-reliability semiconductor device that can finely be processed using SiC and a semiconductor device producing method. A semiconductor device includes: a silicon carbide substrate; a first-conductive-type first silicon carbide layer provided on a first principal surface of the silicon carbide substrate; a second-conductive-type first silicon carbide region formed at a surface of the first silicon carbide layer; a first-conductive-type second silicon carbide region formed at a surface of the first silicon carbide region; a second-conductive-type third silicon carbide region formed below the second silicon carbide region; a trench piercing through the second silicon carbide region to reach the third silicon carbide region; a gate insulating film; a gate electrode; an interlayer insulating film with which the gate electrode is covered; a first electrode that is formed on the second silicon carbide region and the interlayer insulating film in a side surface of the trench while containing a metallic element selected from a group consisting of Ni, Ti, Ta, Mo, and W; a second electrode that is formed on the third silicon carbide region in a bottom portion of the trench and the first electrode while containing Al; a first main electrode formed on the second electrode; and a second main electrode formed on a second principal surface of the silicon carbide substrate.
US08987801B2 Memory cells having a plurality of control gates and memory cells having a control gate and a shield
Various embodiments comprise apparatuses having a number of memory cells. In one such apparatus, each cell has a plurality of control gates. For example, each of two control gates is adjacent a respective side of a charge storage structure. In another apparatus, each cell has a control gate and a shield, such as where the control gate is adjacent one side of a charge storage structure and the shield is adjacent another side of the charge storage structure. Additional apparatuses and methods are described.
US08987799B2 Semiconductor device and method of forming the same
A semiconductor device includes a semiconductor device may include, but is not limited to, a semiconductor substrate, an isolation electrode, a gate electrode, a gate insulating film, and a first insulating film. The semiconductor substrate has a first groove and a second groove. An isolation electrode is positioned in the first groove. The gate electrode is positioned in the second groove. The gate insulating film is adjacent to the gate electrode. The first insulating film is adjacent to the isolation electrode. The isolation electrode is greater in threshold voltage than the gate electrode.
US08987797B2 Nonvolatile memory device and method of forming the same
A nonvolatile memory device has a first active region and a second active region defined in a substrate by a device isolation layer, a Metal Oxide Silicon Field-Effect Transistor (MOSFET) disposed on the first active region and including a first electrode pattern, and a Metal Oxide Silicon (MOS) capacitor disposed on the second active region and including a second electrode pattern, and in which the first electrode pattern is narrower in the widthwise direction of the channel of the MOSFET than the first active region.
US08987796B2 Semiconductor device having semiconductor pillar
Disclosed herein is a device that includes: first to fourth conductive lines embedded in a semiconductor substrate; a first semiconductor pillar located between the first and second conductive lines; a second semiconductor pillar located between the second and third conductive lines; a third semiconductor pillar located between the third and fourth conductive lines; a first storage element connected to an upper portion of the first semiconductor pillar; a second storage element connected to an upper portion of the third semiconductor pillar; and a bit line embedded in the semiconductor substrate connected to lower portions of the first to third semiconductor pillars. At least one of the first and second conductive lines and at least one of the third and fourth conductive lines being supplied with a potential so as to form channels in the first and third semiconductor pillars.
US08987792B2 Merged active devices on a common substrate
Merged active devices on a common substrate are presented. Methods for operating and fabricating such merged active devices are also presented.
US08987789B2 Transistors having stressed channel regions and methods of forming transistors having stressed channel regions
A method of forming a field effect transistor and a field effect transistor. The method includes (a) forming gate stack on a silicon layer of a substrate; (b) forming two or more SiGe filled trenches in the silicon layer on at least one side of the gate stack, adjacent pairs of the two or more SiGe filled trenches separated by respective silicon regions of the silicon layer; and (c) forming source/drains in the silicon layer on opposite sides of the gate stack, the source/drains abutting a channel region of the silicon layer under the gate stack.
US08987788B2 Metal-strapped CCD image sensors
In various embodiments, image sensors include strapping grids of vertical and horizontal strapping lines conducting phase-control signals to underlying gate conductors that control transfer of charge within the image sensor.
US08987786B1 State retention power gated cell
A state retention power gated cell includes a logic cell arranged in two or more rows. The logic cell has an active layer including at least a first well and a second well disposed in first and second rows, respectively. In a normal operation mode, the first well is powered with a first bias voltage, the second well is powered with a second bias voltage, the first power supply line is powered with VDDC, and the second power supply line is powered with VDD. In a standby mode, the first well preferably is powered down, the second well is powered with the second bias voltage, the first power supply line is powered with VDDC, and the second power supply line is powered down.
US08987782B2 Semiconductor structure for forming a combination of different types of devices
There is provided a compound semiconductor wafer that is suitably used to form a plurality of different types of devices such as an HBT and an FET thereon. The semiconductor wafer includes a first semiconductor, a carrier-trapping layer that is formed on the first semiconductor and has an electron-trapping center or a hole-trapping center, a second semiconductor that is epitaxially grown on the carrier-trapping layer and serves as a channel in which a free electron or a free hole moves, and a third semiconductor including a stack represented by n-type semiconductor/p-type semiconductor/n-type semiconductor or represented by p-type semiconductor/n-type semiconductor/p-type semiconductor, where the stack is epitaxially grown on the second semiconductor.
US08987781B2 Structure of heterojunction field effect transistor and a fabrication method thereof
An improved structure of heterojunction field effect transistor (HFET) and a fabrication method thereof are disclosed. The improved HFET structure comprises sequentially a substrate, a channel layer, a spacing layer, a carrier supply layer, a Schottky layer, a Schottky capping layer formed by a higher energy gap material, a tunneling layer formed by a lower energy gap material, a first etching stop layer, and a first n type doped layer. The fabrication method is a multiple selective etching process, which comprises steps of: etching the n type doped layer by using a first etching process to form a first indentation; etching first etching stop layer by using a second etching process to form a second indentation located under the first indentation; etching the tunneling layer by using a third etching process to form a third indentation located under the second indentation, wherein the said first, second and third indentations form a single gate groove, in which the gate electrode can form a Schottky contact with the Schottky capping layer that is made of a higher energy gap material.
US08987777B2 Stacked half-bridge power module
According to an exemplary embodiment, a stacked half-bridge power module includes a high side device having a high side power terminal coupled to a high side substrate and a low side device having a low side power terminal coupled to a low side substrate. The high side and low side devices are stacked on opposite sides of a common conductive interface. The common conductive interface electrically, mechanically, and thermally couples a high side output terminal of the high side device to a low side output terminal of the low side device. The high side device and the low side device can each include an insulated-gate bipolar transistor (IGBT) in parallel with a diode.
US08987773B2 Organic light emitting diode display
An organic light emitting diode display includes: a pixel region; and a peripheral region surrounding the pixel region, the peripheral region including: a gate common voltage line; an interlayer insulating film that covers the gate common voltage line and has a common voltage contact hole exposing part of the gate common voltage line; a data common voltage line that is formed on the interlayer insulating film and comes in contact with the gate common voltage line via the common voltage contact hole; barrier ribs that cover the data common voltage line and have common voltage openings exposing part of the data common voltage line; and a peripheral common electrode that is formed on the barrier ribs and comes in contact with the data common voltage line via the common voltage openings, wherein the barrier ribs are formed at positions corresponding to the boundaries with the common voltage contact hole.
US08987768B2 Semiconductor light emitting device having roughness layer
A semiconductor light emitting device is provided, including a substrate, a first conductive semiconductor layer, an active layer, and a second conductive semiconductor layer that includes a top surface and a bottom surface. The device includes a first roughness layer having a random horn shape and formed with irregular intervals, a second roughness layer, and at least one of a first AlGaN based semiconductor layer and a second AlGaN based semiconductor layer. The second conductive semiconductor layer includes a plurality of apexes on the top surface, where the distance between at least two apexes is of about 0.3 μm to about 1.0 μm. The second roughness layer includes a lower surface having a shape corresponding to the top surface of the second conductive semiconductor layer. The second roughness layer includes an upper surface having a shape corresponding to a top surface of the first roughness layer.
US08987760B2 Organic EL display device and electronic apparatus
Disclosed herein is an organic EL display device in which pixels each including an organic EL element formed by interposing an organic layer between an anode electrode and a cathode electrode are arranged in a matrix, the organic EL display device including: a common layer configured to be included in the organic EL element and be formed in the organic layer in common to the pixels; and a metal interconnect configured to surround periphery of the anode electrode and be electrically connected to the organic layer, wherein potential of the metal interconnect is set to a potential lower than potential of the anode electrode in a non-light-emission state of the organic EL element.
US08987758B2 Barrier film composite and display apparatus including the barrier film composite
A barrier film composite includes a decoupling layer and a barrier layer. The barrier layer includes a first region and a second region that is thinner than the first region.
US08987755B1 Ultraviolet light emitting diode structures and methods of manufacturing the same
Semiconductor structures involving multiple quantum wells provide increased efficiency of UV and visible light emitting diodes (LEDs) and other emitter devices, particularly at high driving current. LEDs made with the new designs have reduced efficiency droop under high current injection and increased overall external quantum efficiency. The active region of the devices includes separation layers configured between the well layers, the one or more separation regions being configured to have a first mode to act as one or more barrier regions separating a plurality of carriers in a quantum confined mode in each of the quantum wells being provided on each side of the one or more separation layers and a second mode to cause spreading of the plurality of carriers across each of the quantum wells to increase an overlap integral of all of the plurality of carriers. The devices and methods of the invention provide improved efficiency for solid state lighting, including high efficiency ultraviolet LEDs.
US08987754B1 Highly directional thermal emitter
A highly directional thermal emitter device comprises a two-dimensional periodic array of heavily doped semiconductor structures on a surface of a substrate. The array provides a highly directional thermal emission at a peak wavelength between 3 and 15 microns when the array is heated. For example, highly doped silicon (HDSi) with a plasma frequency in the mid-wave infrared was used to fabricate nearly perfect absorbing two-dimensional gratings structures that function as highly directional thermal radiators. The absorption and emission characteristics of the HDSi devices possessed a high degree of angular dependence for infrared absorption in the 10-12 micron range, while maintaining high reflectivity of solar radiation (˜64%) at large incidence angles.
US08987750B2 LED chip packaging structure, its manufacturing method, and display device
A LED chip packaging structure, its manufacturing method, and a display device are disclosed. A conductive unit is formed at two opposite sides of a LED chip unit, and comprises a first conductive layer formed at a side of, and electrically connected to, a first electrode, a second conductive layer formed at a side of, and electrically connected to, a second electrode, and an intermediate isolation layer formed at a side of a GaN layer. The LED chip unit and the conductive unit are connected laterally to form an electrical-connection channel as a whole, without welding a gold wire for the conductive channel as in a traditional LED. Thus, the method is able to reduce the total thickness of the LED chip device, increase the thermal conductivity effect of the LED chip and the overall stability, and improve the light-extraction effect of the surface of the LED chip.
US08987748B2 Drain induced barrier lowering with anti-punch-through implant
An integrated circuit containing an MOS transistor with epitaxial source and drain regions may be formed by implanting a retrograde anti-punch-through layer prior to etching the source drain regions for epitaxial replacement. The anti-punch-through layer is disposed between stressor tips of the epitaxial source and drain regions, and does not substantially extend into the epitaxial source and drain regions.
US08987746B2 Array substrate for liquid crystal display device
An array substrate for a liquid crystal display device, comprises: a substrate having a display region and a non-display region; a gate line and first and second data lines on the substrate; first and second thin film transistors in the first and second pixel regions, respectively, the first thin film transistor connected to the gate line and the first data line, the second thin film transistor connected to the gate line and the second data line; a planarization layer on the first and second thin film transistors, the planarization layer having a drain contact hole exposing both of drain electrodes of the first and second thin film transistors; and a pixel electrode and a common electrode over the planarization layer.
US08987744B2 Thin film transistor
A thin-film transistor includes a gate electrode, a capacitance compensation structure, a semiconductor layer, a dielectric layer, a drain electrode and a source electrode. The capacitance compensation structure is disposed on the substrate and electrically connected to the gate electrode. The capacitance compensation structure has a first side facing the gate electrode and a second side facing away from the gate electrode. The semiconductor layer covers a portion of the gate electrode, and at least extends to overlap the first side of the capacitance compensation structure. The dielectric layer has a first opening and a second opening. Both of the first opening and the second opening expose a portion of the semiconductor layer overlapping the gate electrode respectively. The drain electrode is in contact with the semiconductor layer though the first opening. The source electrode is in contact with the semiconductor layer though the second opening.
US08987743B2 Thin film transistor array substrate and method for manufacturing the same
The present disclosure discloses a method for manufacturing a TFT array substrate, comprising: depositing a gate metal layer, a gate insulating layer, a semiconductor layer and a source-drain electrode layer in this order on a base substrate, performing a first photolithograph process to form a common electrode line, a gate line, a gate electrode, a source electrode, a drain electrode and a channel defined between the source electrode and the drain electrode; depositing a passivation layer, performing a second photolithograph process to form a first via hole and a second via hole in the passivation layer; and depositing a pixel electrode layer and a data line layer in this order, perform a third photolithograph process to form a data line connected to the source electrode through the first via hole and a pixel electrode connected to the drain electrode through the second via hole.
US08987741B2 Thin film transistor array panel and the method for manufacturing thereof
Provided is a thin film transistor array panel that includes: a substrate; a gate line and a data line formed on the substrate and at least partially defining a pixel area; a thin film transistor connected to the gate line and the data line; a pixel electrode connected to the thin film transistor and formed in the pixel area; a first common electrode formed under the pixel electrode; a second common electrode formed on the pixel electrode. The pixel area includes an upper pixel area and a lower pixel area, the first common electrode is formed in the upper pixel area, and the second common electrode is formed in the lower pixel area. The pixel electrode includes an upper pixel electrode formed in the upper pixel area and a lower pixel electrode formed in the lower pixel area.
US08987736B2 [100] or [110] aligned, semiconductor-based, large-area, flexible, electronic devices
Novel articles and methods to fabricate the same resulting in flexible, large-area, [100] or [110] textured, semiconductor-based, electronic devices are disclosed. Potential applications of resulting articles are in areas of photovoltaic devices, flat-panel displays, thermophotovoltaic devices, ferroelectric devices, light emitting diode devices, computer hard disc drive devices, magnetoresistance based devices, photoluminescence based devices, non-volatile memory devices, dielectric devices, thermoelectric devices and quantum dot laser devices.
US08987732B2 Ceramic semiconductor capable of increasing the density of surrounding superoxide ions after being heated
Disclosed is a ceramic semiconductor capable of increasing the density of surrounding superoxide ions (O2−) after being heated and passing air. An oxide material capable of enhancing a space charge effect is doped when the ceramic semiconductor is formed, and the ceramic semiconductor has a plurality of through holes, such that after the ceramic semiconductor is electrically conducted to generate current and heat, outer shell electrons of the ceramic semiconductor are separated and remained in the through holes of the ceramic semiconductor and accumulated in the through holes to form an electron cloud. After air passes through the through holes, oxygen in the air collides with an electron and then they combine together to form a superoxide ion (O2−), so as to increase the density of surrounding superoxide ions (O2−).
US08987728B2 Semiconductor device and method of manufacturing semiconductor device
An object is to provide a highly reliable semiconductor device having stable electric characteristics by using an oxide semiconductor film having stable electric characteristics. Another object is to provide a semiconductor device having higher mobility by using an oxide semiconductor film having high crystallinity. A crystalline oxide semiconductor film is formed over and in contact with an insulating film whose surface roughness is reduced, whereby the oxide semiconductor film can have stable electric characteristics. Accordingly, the highly reliable semiconductor device having stable electric characteristics can be provided. Further, the semiconductor device having higher mobility can be provided.
US08987720B2 Transparent surface electrode, organic electronic element, and method for manufacturing transparent surface electrode
The purpose of the present invention is to provide a transparent surface electrode that maintains high transparency, suppresses the occurrence of leak currents, and has superior storage stability and resistance to damage by bending, a method for manufacturing the same, and an organic electronic element using the same. This transparent surface electrode has a metal pattern conductive layer that contains a metal on a transparent base material, and the transparent surface electrode also has a transparent polymer conductive layer, which contains that base material and a conductive polymer, on that metal pattern conductive layer. The transparent surface electrode is characterized by the surface roughness (Ra (surface roughness provided for by JIS, B601 (1994))) of the metal pattern conductive layer being 20 nm or less, and the polymer conductive layer containing a non-conductive polymer having a hydroxyl group.
US08987719B2 Organic light emitting diode display
An organic light emitting diode (OLED) display includes: a substrate; an organic light emitting element formed on the substrate; a first thin film transistor connected to the organic light emitting element and including an amorphous silicon channel region; and at least one other thin film transistor connected to the first thin film transistor and including a polysilicon channel region.
US08987718B2 Dual mode display devices and methods of manufacturing the same
Disclosed are dual mode display devices and methods of manufacturing the same. The dual mode display device may include a first substrate, a first electrode on the first substrate, a second substrate opposite to the first electrode and the first substrate, a second electrode between the second substrate and the first electrode, a third electrode between the first electrode and the second electrode, an optic switching layer between the first electrode and the third electrode, and an organic light-emitting layer between the second electrode and the third electrode.
US08987717B2 Organic light emitting diode display and method of fabricating the same
An organic light emitting diode (OLED) display is provided. The OLED display includes: a substrate; a first electrode on the substrate; a first pixel defining layer exposing at least a portion of the first electrode; a medium layer on the first pixel defining layer and the first electrode, the medium layer including a first region and a second region; a second pixel defining layer overlapping the first pixel defining layer with the first region therebetween; a light emission layer overlapping the first electrode with the first region therebetween; and a second electrode covering the second pixel defining layer and the light emission layer.
US08987715B2 Organic electroluminescence element
An organic electroluminescence device (1) includes: an anode (3); a cathode (4); and an emitting layer (5) provided between the anode (3) and the cathode (4). The emitting layer contains a first host, a second host and a phosphorescent dopant. A triplet energy of each of the first host and the second host is 2.8 eV or more. An ionization potential of the first host is 5.5 eV or less. An affinity Af1 of the first host is smaller than an affinity Af2 of the second host.
US08987714B2 Organic light emitting diode display and method for manufacturing the same
An organic light emitting diode display includes a p-doped layer that can obtain high efficiency at low-voltage driving and low current and prevent leakage current by differentially forming the p-doped layer for each pixel.
US08987712B2 Display device
According to one embodiment, a display device includes a light transmissive substrate, a light transmissive pixel electrode, a switching element, an organic light emitting layer, a light transmissive opposite electrode, a conductive light absorption layer and a conductive film. The light transmissive pixel electrode is provided on the substrate. The switching element is provided on the substrate and electrically connected to the pixel electrode. The organic light emitting layer is provided on the pixel electrode. The light transmissive opposite electrode is provided on the organic light emitting layer. The conductive light absorption layer is provided on the opposite electrode. The conductive film is provided on the light absorption layer.
US08987711B2 Organic electroluminescence element, method for producing organic electroluminescence element, and illumination device using organic electroluminescence element
Provided is an organic electroluminescence element containing a light transmissive base material laminated thereon a transparent electrode, a light emitting layer and a counter electrode in this order, wherein the light transmissive base material contains a light transmissive resin substrate (resin substrate B) provided with a hard coat layer on both surfaces of the light transmissive resin substrate, the hard coat layers containing metal oxide nano particles; and the transparent electrode is formed on one hard coat layer (H1); and a rugged structure is formed on one surface of the other hard coat layer (H2), the one surface being opposite to another surface of the other hard coat layer (H2) which is contacted with the light transmissive resin substrate (resin substrate B).
US08987708B2 Optoelectronic component
An optoelectronic component comprises an organic layer sequence (1), which emits an electromagnetic radiation (15) having a first wavelength spectrum during operation, and also a dielectric layer sequence (2) and a wavelength conversion region (3) in the beam path of the electromagnetic radiation (15) emitted by the organic layer sequence (1). The wavelength conversion region (3) is configured to convert at least partially electromagnetic radiation having the first wavelength spectrum into an electromagnetic radiation (16) having a second wavelength spectrum. The dielectric layer sequence (2) is arranged in the beam path of the electromagnetic radiation (15) emitted by the organic layer sequence between the organic layer sequence (1) and the wavelength conversion region (3) and is at least partially opaque to an electromagnetic radiation having a third wavelength spectrum, which corresponds to at least one part of the second wavelength spectrum.
US08987707B2 Stretchable transistors with buckled carbon nanotube films as conducting channels
Thin-film transistors comprising buckled films comprising carbon nanotubes as the conductive channel are provided. Also provided are methods of fabricating the transistors. The transistors, which are highly stretchable and bendable, exhibit stable performance even when operated under high tensile strains.
US08987705B2 Carbon nanotube transistor employing embedded electrodes
Carbon nanotubes can be aligned with compatibility with semiconductor manufacturing processes, with scalability for forming smaller devices, and without performance degradation related to structural damages. A planar structure including a buried gate electrode and two embedded electrodes are formed. After forming a gate dielectric, carbon nanotubes are assembled in a solution on a surface of the gate dielectric along the direction of an alternating current (AC) electrical field generated by applying a voltage between the two embedded electrodes. A source contact electrode and a drain contact electrode are formed by depositing a conductive material on both ends of the carbon nanotubes. Each of the source and drain contact electrodes can be electrically shorted to an underlying embedded electrode to reduce parasitic capacitance.
US08987703B2 Quantum well device with lateral electrodes
An apparatus includes a substrate, a sequence of crystalline semiconductor layers on a planar surface of the substrate, and first and second sets of electrodes over the sequence. The sequence has a 2D quantum well therein. The first set of electrodes border opposite sides of a lateral region of the sequence and are controllable to vary a width of a non-depleted portion of the quantum well along the top surface. The second set of electrodes border channels between the lateral region and first and second adjacent lateral areas of the sequence and are controllable to vary widths of non-depleted segments of the quantum well in the channels. The electrodes are such that straight lines connecting the lateral areas via the channels either pass between one of the electrodes and the substrate or are misaligned to an effective [1 1 0] lattice direction of the sequence.
US08987702B2 Selectively conducting devices, diode constructions, constructions, and diode forming methods
Some embodiments include selectively conducting devices having a first electrode, a second electrode, and dielectric material between the first and second electrodes. The dielectric material may be configured to conduct current from the first electrode to the second electrode when a first voltage is applied across the first electrode and the second electrode. Furthermore, the dielectric material may be configured to inhibit current from flowing from the second electrode to the first electrode when a second voltage having a polarity opposite that of a polarity of the first voltage is applied across the first electrode and the second electrode. The diode material may comprise a plurality of layers of different dielectric materials arranged in order of increasing barrier height. Quantum wells may form at junctions of layers of the plurality responsive to the first voltage. Some embodiments include diode forming methods.
US08987698B2 Memory constructions
Some embodiments include memory constructions having a plurality of bands between top and bottom electrically conductive materials. The bands include chalcogenide bands alternating with non-chalcogenide bands. In some embodiments, there may be least two of the chalcogenide bands and at least one of the non-chalcogenide bands. In some embodiments, the memory cells may be between a pair of electrodes; with one of the electrodes being configured as a lance, angled plate, container or beam. In some embodiments, the memory cells may be electrically coupled with select devices, such as, for example, diodes, field effect transistors or bipolar junction transistors.
US08987695B2 Variable resistance memory device and method for fabricating the same
A method for fabricating a variable resistance device includes: providing a first insulating layer having a first electrode; forming a first oxide layer including a variable resistance material over the first electrode and the first insulating layer; forming a sacrifice pattern over the first oxide layer; forming a second oxide layer by reacting the first oxide layer exposed by the sacrifice pattern with oxygen; removing the sacrifice pattern; and forming a second electrode over the second oxide layer and the first oxide layer so as to be coupled to the first oxide layer.
US08987690B2 High-energy ion implanter
A high-energy ion implanter includes a beam generation unit that includes an ion source and a mass analyzer, a high-energy multi-stage linear acceleration unit, a high-energy beam deflection unit that changes the direction of a high-energy ion beam toward a wafer, and a beam transportation unit that transports the deflected high-energy ion beam to the wafer. The beam transportation unit includes a beam shaper, a high-energy beam scanner, a high-energy beam collimator, and a high-energy final energy filter. Further, the high-energy beam collimator is an electric field type beam collimator that collimates a scan beam while performing the acceleration and the deceleration of a high-energy beam by an electric field.
US08987689B2 Efficient scan for E-beam lithography
The present disclosure provides a method of increasing the wafer throughput by an electron beam lithography system. The method includes scanning a wafer using the maximum scan slit width (MSSW) of the electron beam writer. By constraining the integrated circuit (IC) field size to allow the MSSW to cover a complete field, the MSSW is applied to decrease the scan lanes of a wafer and thereby increase the throughput. When scanning the wafer with the MSSW, the next scan lane data can be rearranged and loaded into a memory buffer. Thus, once one scan lane is finished, the next scan lane data in the memory buffer is read for scanning.
US08987688B2 Device and method for manufacturing a particulate filter with regularly spaced micropores
Various embodiments disclose devices and methods for fabricating microporous particulate filters with regularly spaced pores wherein sheet membrane substrates are exposed to energetic particle radiation through a mask and the damaged regions removed in a suitable developer. The required depth of field is achieved by using energetic particles to minimize diffraction and an energetic particle source with suitably small diameter.
US08987686B2 Method and spectroscopic analysis appliance, especially for analysing food, with multi-channel treatment of spectral data
A method for the spectroscopic analysis of a sample is provided. The method including the illumination of the sample to be analyzed by a plurality of luminous excitation rays with respective wavelengths; the acquisition and the pre-treatment of frontal fluorescence spectra, each spectrum corresponding to a respective luminous excitation ray; for each sample, the calculation of a score vector by applying a multi-channel statistical model to the pre-treated spectra; and the determination of at least one parameter selected from a quality indicator of the sample and a parameter characterizing a method that has been applied to the sample, from said score vector. The average spectral distance between the luminous excitation rays is at least 50 nm, over a spectral range of at least 100 nm. The invention also relates to an appliance for implementing such a method.
US08987681B2 Ionization method, ion producing device and uses of the same in ion mobility spectrometry
A method for ionizing, using pulses of ionization radiation, an analyte to be examined by way of ion mobility spectrometry using a pulse sequence is modulated with a known time-variable impression pattern is provided. An ionization device for carrying out the method and an ion mobility spectrometry method and an ion mobility spectrometry device that use the ionization method and/or the ionization device are also provided.
US08987678B2 Encapsulation of electrodes in solid media
An inductively-coupled plasma source for a focused charged particle beam system includes a conductive shield that provides improved electrical isolation and reduced capacitive RF coupling and a dielectric fluid that insulates and cools the plasma chamber. The conductive shield may be enclosed in a solid dielectric media. The dielectric fluid may be circulated by a pump or not circulated by a pump. A heat tube can be used to cool the dielectric fluid.
US08987677B2 Charged particle multi-beamlet lithography system, modulation device, and method of manufacturing thereof
The invention relates to a modulation device for use in a charged particle multi-beamlet lithography system. The device includes a body comprising an interconnect structure provided with a plurality of modulators and interconnects at different levels within the interconnect structure for enabling connection of the modulators to one or more pattern data receiving elements. A modulator includes a first electrode, a second electrode, and an aperture extending through the body. The electrodes are located on opposing sides of the aperture for generating an electric field across the aperture. At least one of the first electrode and the second electrode includes a first conductive element formed at a first level of the interconnect structure and a second conductive element formed at a second level of the interconnect structure. The first and second conductive elements are electrically connected with each other.
US08987675B2 Radiation detecting apparatus and radiation imaging apparatus
A radiation detecting apparatus is provided. The radiation detecting apparatus includes a pair of rails extending in a channel direction, a plurality of collimator modules provided in the pair of rails and arranged in the channel direction, each collimator module having a plurality of collimator plates arranged in the channel direction, and a plurality of detector modules provided on a radiation outgoing side of the collimator modules and arranged in the channel direction, wherein each of the collimator modules has a pair of alignment pins extending along an irradiation direction, wherein the rails include a surface of placement for each collimator module, the surface of placement formed with one of concave holes and grooves in which first ends of the alignment pins are fitted, and wherein each of the detector modules has one of concave holes and through holes in which second ends of the alignment pins are fitted.
US08987674B2 Data processing method for nuclear medicine, and a nuclear medicine diagnostic apparatus
A PET apparatus and a processing method according in this invention carry out arithmetic processes in parallel, in steps S4 (forward projection) and S5 (back projection), for every LOR, on list data (created from event data obtained by detecting gamma rays), and can therefore be applied to other arithmetic mechanisms and have versatility. Since parallel processing is carried out on the list data and the parallel processing is carried out in each of steps S4 (forward projection) and S5 (back projection), a competition for memory can be prevented to realize an improvement in speed. As a result, high versatility and an improvement in speed of the calculations can be attained.
US08987673B2 Detector arrangement of an imaging system detector detecting ionizing radiation with air cooling and method for cooling the detector arrangement
A detector arrangement of an imaging system detector detecting ionizing radiation includes a detector carrier, a plurality of detector modules attached to the detector carrier, and a collimator disposed in the radiation direction in front of the detector modules which are disposed on the incident radiation measurement side. In at least one embodiment, at least one air gap is included for conveying cooling air is disposed between the collimator and the measurement sensors of the detector modules. A method is also disclosed for cooling a detector arrangement of a detector rotating around a system axis with a plurality of measurement sensors disposed next to one another and a collimator arranged in the radiation direction in front of the measurement sensors, wherein cooling air is conveyed in or against the system axis direction between the collimator and the measurement sensors which directly cools the surface of the measurement sensors.
US08987671B2 Compact image intensifier tube and night vision system fitted with such a tube
An image intensifier tube and a night vision system fitted with such a tube. The tube body of the image intensifier tube includes a multilayer ceramic substrate fixed in a sealed manner to an input device and to an output device so as to assure leaktightness of a vacuum chamber delimited by the tube body. The multilayer substrate also maintains a microchannel plate arranged between a photocathode and a phosphorus screen, and supplies voltage to the photocathode, the plate, and the phosphorus screen.
US08987670B2 Thermally-protected scintillation detector
Systems, methods, and devices for thermally protecting a scintillator crystal of a scintillation detector are provided. In one example, a thermally-protected scintillator may include a scintillator crystal and a thermal protection element, which may partially surround the scintillator crystal. The thermal protection element may be configured to prevent the scintillator crystal from experiencing a rate of change in temperature sufficient to cause cracking or non-uniform light output, or a combination thereof.
US08987669B2 Laser apparatus for determination of ink dryness
An apparatus determines the dryness of inked paper using laser light absorption technique for application in inkjet printers. Direct in-line feedback is provided as to the effectiveness of the drying of the ink placed deposited upon paper or other media. Associated laser system designs and the technologies employed in the determination of drying efficiency of inks and other liquids placed upon a media are enabled.
US08987668B2 Bolometric detector with a temperature-adaptive biasing
An infrared detector including an array of detection bolometers each having a bolometric membrane suspended above a substrate, and associated with each bolometer: a detection branch, including the bolometer and a circuit performing a biasing according to a voltage set point, a compensation branch, including a compensation bolometer thermalized to the substrate, a circuit performing a biasing according to a voltage set point, an integrator for generating a voltage by integrating a difference between the currents flowing through said branches, a circuit generating a quantity depending on substrate temperature, including: a bolometer thermalized to the substrate, and a circuit for biasing the bolometer, and a circuit for generating the voltage set points according to said quantity. When the array is exposed to a uniform reference scene, the average of the differences between currents flowing through said branches is within the integrator dynamic range for a substrate temperature range from −30° C.-90° C.
US08987667B2 Systems and methods for image lag mitigation for buffered direct injection readout with current mirror
Embodiments relate to systems and methods for image lag mitigation for a buffered direct injection readout circuit with current mirror. A photo detector device is coupled to a buffered direct injection (BDI) circuit, in which an operational amplifier and other elements communicate the output signal from the detector to subsequent stages. The BDI output is transmitted to a first current mirror, which can be implemented as a Säckinger current mirror. The first current mirror is coupled to a second current mirror, one of whose outputs is a fixed bias current. Image lag can be controlled by the fixed bias current, rather than the photocurrent produced directly by the optical detector. In aspects, the negative feedback provided by the first current mirror can increase the modulation of the second current mirror. This gain factor can reduce image lag to a significantly lower point than the lag experienced by known BDI-current-modulated readout circuitry without Säckinger current mirror.
US08987666B2 Apparatus and method for sensing temperature
A temperature sensing apparatus and method are described to detect a change in a frequency due to a change in a temperature. An infrared light sensing apparatus and method are also provided. The temperature sensing apparatus may include an electrode to generate an electrical signal, a piezoelectric layer to convert the electrical signal into an acoustic wave, and a temperature sensitive layer formed by doping impurities in one or more structures formed on a substrate. Additionally, the infrared light sensing apparatus may convert into heat infrared light incident to an infrared light absorption layer, using an infrared light reflection layer and the infrared light absorption layer. A temperature sensitive layer may detect a change in a resonant frequency based on a change in a temperature of the heat, and may detect a change in infrared light based on the change in the resonant frequency.
US08987660B2 Mass spectrometry with selective ion filtration by digital thresholding
The methods described herein generally relate to characterization of large analytes, such as biomolecules, by molecular mass analysis. Specifically, the methods are directed to molecular mass analysis of singly— or multiply-charged ions by selective ion filtering carried out by a digital thresholding process.
US08987659B2 Pet calibrations with varying coincidence windows
When calibrating a positron emission tomography (PET) scanner, a radioactive calibration phantom is scanned over a period of several half lives to acquire a plurality of frames of scan data. Interlaced timing windows are employed to facilitate acquiring coincidence data for a plurality of coincidence timing windows and energy windows during a single calibration scan. Coincident events are binned according to each of a plurality of selected coincidence windows, and the PET scanner is calibrated for each of the plurality of coincidence timing windows using data acquired from the single calibration scan.
US08987657B2 Spatial filter measuring arrangement, device, and associated method having a mirror array with movable mirror elements for generating a grating structure
The invention relates to a spatial filter measuring arrangement (1) and a spatial filter measuring device (2) comprising at least one sensor (4, 5; 41I-41IV; 51) and a spatial filter, wherein electromagnetic radiation, in particular light, that is emitted or reflected by a measurement object (13), is imaged onto the sensor (4, 5; 41I-41IV; 51, 52) by means of the spatial filter. The invention further relates to a method for spatial filter measurement. The spatial filter measuring arrangement according to the invention is further developed in that the spatial filter is designed as a micro-mirror array which has mirror elements (21-21′″) which can be moved about respective angular positions.
US08987648B2 Solid-state imaging apparatus having a sealing portion to reduce water invasion into the plurality of pixels and the peripheral circuit in a first member and a second member and method for manufacturing the solid-state imaging apparatus
A solid-state imaging apparatus includes a first substrate that includes a plurality of photoelectric conversion units, a second substrate that includes at least a part of a readout circuit configured to read signals based on electric charges of the plurality of photoelectric conversion units and a peripheral circuit including a control circuit, and a wiring structure that is disposed between the first substrate and the second substrate and includes a pad portion electrically connected to the peripheral circuit via a draw-out wiring and an insulating layer. The wiring structure has, at least at a part thereof, a seal ring disposed in such a way as to surround the photoelectric conversion units and the peripheral circuit.
US08987647B2 Low power wide dynamic range CMOS imager output circuit having a threshold detector to set a gain to be applied by a readout circuitry
An imager has an array of pixels arranged in rows and columns, readout circuitry electrically coupled to the columns to receive signals from the pixels, the readout circuitry having at least one signal path with gain switching, and a threshold detector electrically coupled to the readout circuitry to set a gain to be applied by the readout circuitry.
US08987644B2 Microwave heating apparatus
A high-frequency heating apparatus of the present invention includes a heating chamber to which a heating plate for loading a subject to be heated thereon is detachably attached, a microwave generating unit, a waveguide for transmitting a microwave from the microwave generating unit, a rotation antenna for radiating the microwave into the heating chamber from the waveguide, a driving unit for turning/driving the rotation antenna, an operating portion capable of choosing the grill menu by which the subject to be heated put on the heating plate is heated and a hot-up menu by which the subject to be heated is heated without the heating plate, and a controlling unit for controlling the driving unit based on an output signal form the operating portion, wherein the controlling unit controls to vary a direction of a sharp portion of a radiation directivity of the rotation antenna in response to the output signal from the operating portion.
US08987641B2 High performance heater
Systems and methods are provided for a high performance heater. In an embodiment, the high performance heater comprises a first stackable tray comprising a first alignment pin that insulates a first heating element disposed in the first stackable tray; a second stackable tray comprising a second alignment pin that insulates a second heating element disposed in the second stackable tray, wherein a top of the first alignment pin fits into a cutout of a bottom of the second alignment pin when the first and second stackable trays are stacked, and wherein the first and second stackable trays comprise one or more materials, an outer diameter and an inner diameter, and wherein an area between the outer diameter and the inner diameter of the stackable trays comprises at least one cutout portion that allows expansion of the material(s) when the high performance heater is at high temperatures.
US08987640B2 Axial resistance sheathed heater
An axial resistance sheathed heater is presented. The axial resistance sheathed heater includes a retaining sheath having a first end and a second end and a resistance wire completely disposed within the retaining sheath. The heater further includes a first conductor rod partially disposed within the retaining sheath and extending beyond the first end of the retaining sheath, the first conductor rod in direct electrical communication and direct mechanical communication with the resistance wire; and a second conductor rod partially disposed within said retaining sheath and extending beyond the second end of the retaining sheath, the second conductor rod in direct electrical communication and direct mechanical communication with the resistance wire. The resistance wire, the first conductor rod and the second conductor rod comprise a circuit achieving a power to voltage rating of about 5000:24.
US08987638B2 Engine driven welding machine
An engine driven welding machine in which a welding generator is driven by an engine, and the engine performs an idle operation when a welding operation is stopped by including an engine stop signal forming circuit which forms a stop signal for stopping an operation of the engine when time of the idle operation exceeds a predetermined time, a direct-current power supply connected to an output terminal of the welding machine, voltage detecting means which detects a voltage change of the output terminal, a restart detecting circuit which forms a restart signal for restarting the engine when the detected voltage by the voltage detecting means shows a predetermined change mode for starting the welding operation, and an engine control circuit which stops the engine in response to the stop signal, and restarts the engine in response to the restart signal.
US08987636B2 Method and system for multi pass weld preparation using a cutting torch
Systems, methods and software products generate multi-pass contours for controlling a numerical control (NC) machine to cut out a part with weld preparation. Weld preparation information is combined with an electronic description of the part to form an enhanced electronic file. Multi-pass contours, usable to control an NC machine to cut out the part with at least one bevel, are generated based upon the enhanced electronic file.
US08987627B2 Dual seam electric resistance welded tubes
A method of continuously forming a dual seam welded tubular product includes the steps of providing two coils of sheet metal material, uncoiling the two coils and forming the material into opposing sections, bringing the two opposing sections together at a convergence angle of less than about 4°; and welding the two seams created between the two opposing sections. An apparatus is configured to bring the sections together at a convergence angle less than about 4° to produce the tubular product. The tubular product may have a diameter greater than 26 inches.
US08987625B2 Capacitive touch panel structure
A capacitive touch panel structure includes a transparent substrate, a conductive layer, a polymeric transparent substrate and an adhesive layer. The transparent substrate has a first side and a second side. The conductive layer is disposed on the second side. The polymeric transparent substrate has a third side and a fourth side. The adhesive layer is disposed between the transparent substrate and the polymeric transparent substrate. By means of the design of the capacitive touch panel structure, the number of the conductive layer is reduced to lower the manufacturing cost.
US08987624B2 Capacitive input device with removable cover
An information handling system can include a base, a printed circuit board including a capacitive switch, and a cover. The printed circuit board can be attached to the base, and the cover can lie adjacent to the printed circuit board. The capacitive switch can be configured to change state when an object is close to the cover. The cover can be configured such that it can be detached from the remainder of the information handling system while the printed circuit board remains attached to the base. The configuration of the printed circuit board and cover can be particularly useful when maintaining a keyboard or a touch pad or when replacing the cover.
US08987623B2 Slide switch for use in electronic apparatus, and electronic apparatus
A slide switch capable of enhancing the accuracy of detecting a slide operation position of a slide lever and the operability of the slide lever without increasing the number of components and an installation space for the slide switch. An elastically-deformable click portion is disposed on a line passing through the center of a slide shaft of the slide lever and extending in a sliding direction in which the slide lever slides, moves integrally with the slide lever, and gets over a convex portion formed in a base member to generate a click force. In an accommodation space which accommodates the click portion and a plurality of armature portions, the click portion and one armature portion of the plurality of armature portions are separated from each other by a first partition, and the click portion and the other armature portion are separated from each other by a second partition.
US08987617B2 Multicolor light-emitting computer input device
A multicolor light-emitting computer input device includes a key switch module including a bottom plat having through holes, press members spaced above the bottom plate, and linking members respectively coupled between the bottom plate and the press members for moving the press members up and down, a circuit board arranged above the bottom plate and carrying light-emitting diodes in the through holes of the bottom plate and a light guide cap of a selected color capped around each light-emitting diode, elastomer members arranged the top side of the circuit board, and a light guide panel arranged at the bottom side of the bottom plate for receiving light from the light-emitting diodes and the respective light guide caps and guiding the received light toward the press members.
US08987616B2 Weight scale for a patient lift system, a control system for the weight scale, and a method for weighing a patient supported on the weight scale
A weight scale for a patient lift system includes a frame assembly. A plurality of force sensors are coupled to the frame assembly. Each of the plurality of force sensors is configured to generate a signal indicative of a measured weight force. A foot rest panel is coupled to the frame assembly. The foot rest panel is configured to support a patient. An angle sensor is operatively coupled to the frame assembly. The angle sensor is configured to generate a signal indicative of an angle of the frame assembly with respect to a horizontal reference plane. A controller is coupled in signal communication with each force sensor and the angle sensor. The controller includes one or more processors configured to receive signals from each force sensor and the angle sensor to determine an actual weight force of the patient.
US08987613B2 Automated weighing and franking mail pieces at transport speed
Methods and apparatus for weighing an article, such as a mail piece, while the article is moving at high speed, and for checking that the correct amount of postage has been paid for delivery of the article. An article (900) is received from an intake transport (1200), and gripped in a weighing station (1310), in between a capstan roller and a pinch roller (1316), which are synchronized to minimize slipping. A first precision closed-loop servo system (1252, 1250) alters the speed of the article, and in the process acquires torque data for storage and analysis (1212, 1282) to determine weight. Correct postage is determined in a processor (1212), and the postage actually paid is checked either by image analysis (1204, 1214, 1280) or by accessing a stored mailer manifest (1280).
US08987612B2 Bushings, apparatuses including bushings, and associated methods
Bushings include a tubular body that defines a through-bore for receiving a fastener for mounting a component to an object. The tubular body includes end regions and a plurality of spring elements spaced circumferentially around the tubular body and extending longitudinally along the tubular body between the end regions. Also disclosed are apparatus that include bushings, such as aircraft, and associated methods of utilizing bushings and of manufacturing bushings.
US08987611B2 Electromagnetic shielding article
A shielding article includes a polymeric conductive layer and a protective layer disposed adjacent the polymeric conductive layer. The polymeric conductive layer provides electromagnetic shielding characteristics so as to prevent receipt of data from a radio frequency information component by an external device when the component is located between the external device on one side and the polymeric conductive and protective layers on the other side. The shielding article may be shaped to substantially surround the radio frequency information component.
US08987610B2 Vent structure for electromagnetic shielding
A vent structure for electromagnetic shielding includes: a conductive shielding case having a vent formed therein: a conductive shielding duct installed on the shielding case so as to cover the vent, including a space formed perpendicular to the direction of motion of air discharged from the vent to vent the air and a discharge port connected from the space to the outside to discharge the air introduced into the space to the outside, and shielding electromagnetic waves; and an EMI (Electro Magnetic Interference) gasket installed at a bonding surface between the shielding case and the shielding duct, and electrically connecting the shielding case and the shielding duct.
US08987609B2 Printed circuit board structure
A printed circuit board structure comprises a base layer, an insulation layer, and a signal layer sandwiched between the base layer and the insulation layer. The insulation layer includes a plurality of conductive regions. The conductive regions are used for providing a current reflowing path. Each of the conductive regions comprises a plurality of empty regions which are spaced from each other. A space inside the empty region is substantially hollow, and spaces between adjacent empty region are filled with cooper.
US08987607B2 Conductive particle, and anisotropic conductive film, bonded structure, and bonding method
To provide a conductive particle, which contains a core particle, and a conductive layer formed on a surface of the core particle, where the core particle is formed of a resin, or a metal, or both thereof, and the conductive layer contains a phosphorus-containing hydrophobic group at a surface thereof.
US08987605B2 Formation of connectors without UBM
A device includes a substrate, a metal pad over the substrate, and a passivation layer having a portion over the metal pad. A post-passivation interconnect (PPI) is electrically coupled to the metal pad, wherein the PPI includes a portion over the metal pad and the passivation layer. A polymer layer is over the PPI. A solder ball is over the PPI. A compound includes a portion adjoining the solder ball and the polymer layer, wherein the compound includes flux and a polymer.
US08987601B2 Partition-attached shield pipe and wire protection structure for end section thereof
A plurality of wires are prevented from being damaged from contact with an edge of an end portion of a shield pipe through which the wires are inserted. A shield pipe through which a wire harness including a plurality of wires routed in a hybrid automobile or an electric automobile has partition walls separating the plurality of inserted wires one by one and projecting continuously in an axis direction of the pipe from an inner surface of a peripheral wall of a pipe main body. The partition walls corresponding to the number of wires inserted through the shield pipe are provided radially in a cross section. Each of the partition walls has at least one bending portion extending in the axis direction of the pipe.
US08987591B2 Communication channels with crosstalk-mitigating material
Alien crosstalk in communication channels is decreased with the use of crosstalk-mitigating materials. Electrical communication cables may be provided with crosstalk-mitigating materials that surround twisted pairs in the cables. According to one embodiment, the crosstalk-mitigating material is an electrically resistive material having electrically conductive areas placed thereon. Such a material mitigates the effects of electrical and magnetic fields that would normally lead to alien crosstalk between communication channels.
US08987588B2 Method for fabricating solar cell
A solar cell and method of fabricating the same are provided. The substrate of the solar cell has heavily-doped regions and lightly-doped regions. The anode and the cathode are disposed on the back surface of the substrate, and thus the amount of incident light on the front surface of the substrate is increased. The anode and the cathode are in contact with the heavily doped regions to form selective emitter structure, and thus the contact resistance is reduced. The lightly-doped regions, which are not in contact with the anode and the cathode, have lower saturation current, and thus recombination of hole-electron pairs is reduced, and absorption of infrared light is increased.
US08987586B2 Conductive paste and electronic device and solar cell including an electrode formed using the conductive paste
A conductive paste including a conductive powder, a metallic glass, and an organic vehicle, wherein the metallic glass has a resistivity that is decreased when the metallic glass is heat treated at a temperature that is higher than a glass transition temperature of the metallic glass.
US08987579B2 Power converter
A power converter is provided and includes a heat collector surface, n- and p-legs formed of n- and p-type thermoelectric materials, respectively, which are each disposed in thermal communication with the heat collector surface, parallel electric busses electrically coupled to the n- and p-legs and a housing, which is electrically decoupled from the busses, to support the heat collector surface at a predefined distance from a heat pipe.
US08987575B1 Automated tihai clock
A system and method for creating and visualizing valid tihais conforming to a predetermined framework using a rhythm engine, mechanical or software/firmware controlled, to control an interrelationship of a set of dynamic indicators.
US08987574B2 System and method for analysis and creation of music
A method and system for analyzing patterns in the relationships of notes of an input piece of music. The method comprises generating a set of the most frequently occurring note pitches in ascending pitch order that matches an interval pattern, and detecting out-of-key pitches that lie outside of this interval pattern. One or more potential key sequence bifurcations are identified which represent a list of possible key sequences according to forwards and backwards analysis. By finding patterns of repetition in the chordal sequences that may be generated according to these key sequence bifurcations, a key sequence that allows the most frequently recurring chord sequences may be chosen. Chord sequences may be analyzed by using ghost chords, temporary harmonic structures that are created, updated and finalized over time according to a combination of essential and inessential note fragments. The method further comprises identifying non-harmony pitches according to the analyzed chord sequence.
US08987573B1 Music teaching device and method
A novel Janko-type keyboard with attachable/detachable touch plates is disclosed. The touch plates have a coloring differing from traditional keyboards. A novel music tablature corresponding to the keyboard design is provided. Also a novel piano notation system corresponding to the keyboard design is provided. Finally a method to teach playing Janko-type keyboard is provided, where the method included virtual Janko-keyboard on computer touch screen, optionally an actual electronic Janko-keyboard attached to the computer and computer programs providing music notation on tablature system of this disclosure.
US08987570B2 Keyboard device for electronic musical instrument
A keyboard device includes plural white keys, plural black keys, and plural hammers respectively engaged with the plural white and black keys. Vertical length of a drive portion for a first key and a second key are set the same, the first and second keys both being white keys, or both being black keys. Longitudinal position of hammer support portion of a first hammer engaged with the first key and longitudinal position of a hammer support portion of a second hammer engaged with the second key are set the same. Vertical positions of hammer support portions of the first and second hammers are respectively set according to a distance from a front end of an operation portion of the first key and a key support portion and a distance from a front end of an operation portion of the second key and a key support portion.
US08987567B1 Maize inbred PH1CV5
A novel maize variety designated PH1CV5 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1CV5 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1CV5 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1CV5 or a locus conversion of PH1CV5 with another maize variety.
US08987562B2 Soybean variety A1026312
The invention relates to the soybean variety designated A1026312. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026312. Also provided by the invention are tissue cultures of the soybean variety A1026312 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026312 with itself or another soybean variety and plants produced by such methods.
US08987558B2 Cytoplasmic male sterile leek plants, methods for the preparation and use thereof, and a cytoplasmic male sterile garlic plant
The present invention relates to cytoplasmic male sterile leek (Allium ampeloprasum) plants comprising cytoplasmic encoded male sterility originating from garlic plant (Allium sativum L.) with deposit number NCIMB 41563. Furthermore, the invention relates to a method for providing hereof. And the invention relates to use of the provided plant and of garlic for providing cytoplasmic encoded male sterility.
US08987557B2 Promoters and methods thereof
A promoter, which may be used to transform a plant and/or express a gene substantially uniformly in substantially all organs and/or tissues of a plant, and which may include a constitutive expression promoter for transforming a monocot plant. A vector including a promoter, which may include a recombinant plant expression vector. A method of producing a target protein using a vector, and a method of producing a transformed cell and/or plant using a vector. A transformed plant, a transformed seed and a transformed cell are included, which may be formed by the method of producing the same using a vector.
US08987555B2 Reducing levels of nicotinic alkaloids in plants
Two genes, A622 and NBB1, can be influenced to achieve a decrease of nicotinic alkaloid levels in plants. In particular, suppression of one or both of A622 and NBB1 may be used to decrease nicotine in tobacco plants.
US08987553B2 Modulation of ACC synthase improves plant yield under low nitrogen conditions
The invention provides methods for improving plant yield, particularly under nitrogen limiting conditions. According to the invention, applicants have discovered that modulating ACC synthase activity in plants improves yield of plants, even when grown under low nitrogen conditions. The same plants, while demonstrating improved yield over non-modified plants, exhibited no deleterious effects under normal nitrogen conditions. The invention further provides methods using recombinant expression cassettes, host cells and transgenic plants.
US08987552B2 Nucleic acid molecules that target the vacuolar ATPase H subunit and confer resistance to coleopteran pests
Nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests are disclosed. Methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby are also disclosed.
US08987551B2 Modified oil encapsulating proteins and uses thereof
The invention provides modified oleosins, including at least one artificially introduced cysteine, and methods and compositions for producing the modified oleosins. Also provided are polynucleotides encoding the modified oleosins, constructs and host cells comprising the polynucleotides, methods for producing oil bodies comprising the modified oleosins, in vivo and in vitro, and methods for producing oil in host cells and plants. The invention also provides methods for increasing the rate of CO2 assimilation in photosynthetic cells and plants, and involves reducing or preventing lipid recycling, and/or expressing modified oleosins with artificially introduced cysteine residues in the photosynthetic cells and plants. Also provided are methods for increasing oil production in plants, via expression of modified oleosins in the non-photosynthetic tissues/organs of plants. The method also optionally includes the step of extracting the oil from the non-photosynthetic tissues/organs of the plant, or processing the oil rich non-photosynthetic tissues/organs into animal or biofuel feedstocks.
US08987550B1 Maize hybrid X75C836
A novel maize variety designated X75C836 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X75C836 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X75C836 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X75C836, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X75C836. This invention further relates to methods for producing maize varieties derived from maize variety X75C836.
US08987549B2 Tomato fruit having increased firmness
This invention relates to a tomato fruit with significantly increased firmness due to the presence of at least one genetic element (or quantitative trait loci; QTLs) in the cultivated plant producing said tomato fruit, compared to fruit from a control tomato plant which does not have said genetic element(s). A cultivated tomato plant producing tomato fruit with significantly increased fruit firmness and a method for detecting QTLs linked to significantly increased fruit firmness are also provided.
US08987548B2 Soybean plants having superior agronomic performance and method for their production
This invention provides compositions including favorable alleles of marker loci associated with genetic elements contributing to superior agronomic performance. Also provided are markers for identifying favorable alleles of marker loci associated with genetic elements involved in superior agronomic performance, as well as methods employing the markers.
US08987547B1 Methods for characterizing soybean aphid biotypes
The present invention is directed, in various embodiments, to methods for characterizing soybean aphid biotypes, evaluating soybean plants for soybean aphid biotype resistance, producing a soybean plant having at least partial resistance to a soybean aphid biotype, and maintaining the biodiversity of soybean aphid biotypes from particular locations under laboratory conditions.
US08987546B2 Orange transgenic fluorescent ornamental fish
The present invention relates to transgenic fluorescent orange ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing.
US08987544B2 Article with heat-activatable expandable structures
An absorbent article has a longitudinal direction, a transverse direction, a first major surface which forms a body-facing surface of the absorbent article, and a second major surface disposed distally from the first major surface which forms a garment-facing surface of the absorbent article. The article includes an absorbent core positioned between the first major surface and the second major surface. The article also includes at least one heat-activatable expandable structure. The at least one heat-activatable expandable structure is disposed on or below the first major surface. Application of heat to the heat-activatable expandable structure causes the heat-activatable expandable barrier structure to form distinctive designs, barriers and/or channels.
US08987543B1 Sizeable sanitary or incontinence pad with med alerts
A sanitary or incontinence pad includes micro-perforated seams. On each side of the micro-perforated seam are sealed seams to retain the absorbent material within the pad. Tearing along the micro-perforated seam allows the pad to be separated into smaller functioning units to better meet the user's needs. Medical alert reagent tabs can be added to the surface of the pads to alert the user of possible health conditions.
US08987542B2 Decontamination method and apparatus for solid-state material contaminated by radiocesium
A decontamination method of solid-state material contaminated by radiocesium comprising bringing the solid-state material containing radiocesium in contact with a first processing solution and preferably eluting cesium ion from the solid-state material to the liquid phase under the presence of potassium ion or ammonium ion.
US08987541B2 Coal waste treatment processes and products
Techniques for disposing of one or more toxic materials, such as coal waste (e.g., fly ash, sludge, etc.), include incorporating the toxic materials into artificial feldspar or forming artificial feldspar from the toxic material(s). The artificial feldspar may be used to form an artificial aggregate, which may be used in a construction material, as road base, as a fill material or for any other suitable purpose. Artificial aggregates that are formed from toxic materials are also disclosed, as are construction materials that include such artificial aggregates.
US08987540B2 Process for removing oxygenate from an olefin stream
The present invention relates to a process for removing oxygenate from an olefin stream comprising oxygenate, comprising providing to an oxygenate recovery zone the olefin stream comprising oxygenate and a solvent comprising propanol, treating the olefin stream comprising oxygenate with the solvent, and retrieving from the oxygenate recovery zone at least one oxygenate-depleted olefinic product stream comprising olefin and a spent solvent comprising at least part of the oxygenate.
US08987535B2 Process for the manufacture of hydrochlorofluoroolefins
The invention also relates a process for the manufacture of trans 1-chloro3,3,3-trifluoropropene. The process comprises an isomerization step from cis 1233zd to trans 1233zd.
US08987533B2 Production method for 1-chloro-3,3,3-trifluoropropene
A production method of 1-chloro-3,3,3-trifluoropropene according to the present invention includes reaction of 1,1,1,3,3-pentachloropropane with hydrogen fluoride, characterized in that the concentrations of respective catalytic components in the 1,1,1,3,3-pentachloropropane as the raw material is controlled to a predetermined level or less. By controlling the concentrations of the respective catalytic components in the 1,1,1,3,3-pentachloropropane to the predetermined level or less, it is possible to improve the problems of shortening of catalyst life, retardation of reaction and scaling or corrosion of equipment in the production of the 1-chloro-3,3,3-trifluoropropene. In addition, the 1,1,1,3,3-pentachloropropane can be obtained selectively with high yield by telomerization reaction of carbon tetrachloride and vinyl chloride. The present invention is thus useful as the method for industrially advantageous, high-yield production of the 1-chloro-3,3,3-trifluoropropene.
US08987532B2 Process for producing 1,2-dichloro-3,3,3-trifluoropropene
Disclosed is a process for producing 1,2-dichloro-3,3,3-trifluoropropene, which is characterized by that 1-halogeno-3,3,3-trifluoropropene represented by the general formula [1]: (In the formula, X represents a fluorine atom, chlorine atom or bromine atom.) is reacted with chlorine in a gas phase in the presence of a catalyst. It is possible by this process to produce 1,2-dichloro-3,3,3-trifluoropropene in an industrial scale with good yield by using 1-halogeno-3,3,3-trifluoropropene, which is available with a low price, as the raw material.
US08987531B2 Syntheses of Z-olefin-containing lepidopteran insect pheromones
The present invention is directed to methods of synthesizing insect pheromones, particularly lepidopteran insect pheromones, their precursors and derivatives from inexpensive, readily available starting materials using olefin metathesis catalysis.
US08987530B2 Production of alcohols having at least four carbon atoms from carbonaceous materials
A process for producing alcohols from carbonaceous materials such as biomass. The carbonaceous material, such as biomass, is gasified to produce synthesis gas. The synthesis gas then is subjected to a plurality of reactions to produce alcohols having at least four carbon atoms such as butanol and isobutanol.
US08987529B2 Process for preparing polyether polyols
The present invention relates to a process for solvent-free preparation of polyether polyols with blockwise polyether chain structure, based on starter compounds solid at room temperature.
US08987527B2 Process for obtaining trimethylolpropane-enriched product streams from the secondary streams of trimethylolpropane preparation
A process for obtaining trimethylolpropane-enriched product streams from the forerun fractions obtained in the distillative purification of trimethylolpropane is characterized in that: (a) the forerun fractions are treated separately or in combination at a temperature of 160 to 280° C. and at a pressure of 1 to 30 MPa with hydrogen in the presence of a hydrogenation catalyst and an acidic compound; and (b) the reaction mixture obtained after step a) is separated by distillation into a trimethylolpropane-enriched, catalyst-free product stream and a catalyst-containing product stream. The trimethylolpropane is prepared by the Cannizzaro process using alkali metal or alkaline earth metal compounds or stoichiometric amounts of trialkylamines, or is produced by the hydrogenation process in the presence of catalytic amounts of trialkylamines or alkali metal or alkaline earth metal compounds.
US08987525B2 Process for the preparation of polyhydroxystilbene compounds by deprotection of the corresponding ethers
A process for the preparation of polyhydroxystilbene compounds (particularly resveratrol, oxyresveratrol, piceatannol, gnetol and the like) by deprotection of the corresponding ethers using aluminum halide and a secondary amine is provided.
US08987518B2 Polyamines and process for preparation thereof
The present invention relates to polyamines and to a process for preparing polyamines.
US08987515B2 Cross products and co-oligomers of phenylenediamines and aromatic amines as antioxidants for lubricants
Radical initiated reactions of phenylenediamines with alkylated aromatic amines produce an antioxidant mixture containing cross reaction products of the phenylenediamines and alkylated aromatic amines which are useful, for example, as antioxidants, stabilizers, and antiozonants for lubricants, electronic chemicals, rubbers, urethanes and other polymer resins, crop protection, pharmaceuticals, dyes and toners.
US08987512B2 Method and apparatus for carbonylating methanol with acetic acid enriched flash stream
A carbonylation process for producing acetic acid including: (a) carbonylating methanol or its reactive derivatives in the presence of a Group VIII metal catalyst and methyl iodide promoter to produce a liquid reaction mixture including acetic acid, water, methyl acetate and methyl iodide; (b) feeding the liquid reaction mixture at a feed temperature to a flash vessel which is maintained at a reduced pressure; (c) heating the flash vessel while concurrently flashing the reaction mixture to produce a crude product vapor stream, wherein the reaction mixture is selected and the flow rate of the reaction mixture fed to the flash vessel as well as the amount of heat supplied to the flash vessel is controlled such that the temperature of the crude product vapor stream is maintained at a temperature less than 90° F. cooler than the feed temperature of the liquid reaction mixture to the flasher and the concentration of acetic acid in the crude product vapor stream is greater than 70% by weight of the crude product vapor stream.
US08987511B2 Process for producing adipic acid crystals
A method for producing crystals of adipic acid is described. In particular, a method for recovering adipic acid in the form of crystals with low impurity content, obtained by crystallization steps in particular using reaction media for synthesizing adipic acid is described. A purification method including a step of crushing the crystals for easier removal or the migration of the impurities in the crystals is also described.
US08987510B2 Method for removal of the cyclic diester of a 2-hydroxy alkanoic acid from a vapor
The invention relates to a method for the removal of the cyclic diester of a 2-hydroxy alkanoic acid from a vapor containing said diester, wherein the vapor is contacted with an aqueous solution so that the diester dissolves in said solution. According to the invention, the method is characterized in that the solution is an alkaline solution, preferably having a pH above 10. The problem of the formation of slurries of the diester in the aqueous solutions can be prevented by the present invention. The method can be applied with great advantage in the production or conversion of lactide.
US08987509B2 Recovery of volatile carboxylic acids by extractive evaporation
A process for recovering a volatile carboxylic acid from an aqueous stream containing same comprising the steps of: (a) evaporating the aqueous stream to produce a vapour stream comprising the volatile carboxylic acid that has been vapourized and water vapour, which aqueous stream is produced by a conversion process using a lignocellulosic feedstock as a substrate; (b) contacting the vapour stream with an organic solvent so as to extract the volatile carboxylic acid present in the vapour stream, thereby producing a liquid stream comprising the organic solvent and the volatile carboxylic acid, and a water vapour stream, wherein the organic solvent has an atmospheric boiling point of at least about 150° C. and is insoluble in water; and (c) separating the volatile carboxylic acid from the organic solvent.
US08987508B2 Process for the preparation of chelated compound
The present invention generally relies on a process for the preparation of chelated compounds, comprising the selective interaction between a solid matrix and a chelating agent. In more details, the present invention enables the preparation of chelated compounds useful as diagnostic agents, in high yields and in a reliable way.
US08987504B2 Aminohydroxylation of alkenes
The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds.
US08987500B2 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives
The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.
US08987497B2 Process for the oxidation of organic carbonyl compounds
A process for the oxidation of an organic carbonyl compound comprising reacting the organic carbonyl compound, optionally in the presence of a solvent, with hydrogen peroxide in the presence of a catalyst comprising a tin-containing zeolitic material having an MWW-type framework structure.
US08987495B2 Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method
Provided is an efficient technology for synthesizing diamino acids (diamino acid derivatives). Disclosed is a manufacturing method for diamino acid derivatives wherein the fluorenyl groups of the diamino acid derivative starting materials represented by General Formula [II] or [IV] are removed.
US08987494B2 Low molecular weight carbosilanes, precursors thereof, and methods of preparation
A series of silicon compounds are provided, which are excellent precursors to small carbosilanes, such as 1,3,5-trisilapentane, 2,4,6-trisilaheptane, tris(silylmethyl)silane and tetrakis(silylmethyl)silane. A method of preparing a carbosilane involves forming a Grignard, lithium, or metallic reagent from a halomethyltrialkoxysilane, reacting the Grignard, lithium, or metallic reagent with a dihalodihydridosilane, a trihalohydridosilane, a tetrahalosilane, a dialkoxydihydridosilane, a trialkoxyhydridosilane, or a tetraalkoxysilane to yield a carbosilane precursor, and reducing the precursor to form the carbosilane.
US08987493B2 Process for synthesis of silane dipeptide analogs
The invention provides a method of preparing silane dipeptide analogs, comprising the steps of treating a solution of a substituted 1,2-oxasilolane with lithium metal to form a solution of the dilithium salt of a substituted 3-hydroxypropylsilanol, and reacting the solution of the dilithium salt of the substituted 3-hydroxypropylsilanol with a substituted enamine.
US08987492B2 Ruthenium-diamine complex and method for producing optically active compound
Provided is a ruthenium complex that is represented by general formula (1*) and is useful as an asymmetric reduction catalyst. (In the formula, * is an asymmetric carbon atom; R1 is an arenesulfonyl group, and the like; R2 and R3 are a phenyl group, and the like; R10 through R14 are selected from a hydrogen atom, C1-10 alkyl group, and the like, but R10 through R14 are not simultaneously hydrogen atoms; X is a halogen atom and the like; j and k are each either 0 or 1; and j+k is 0 or 2.)
US08987487B2 Method for removing phosphorus-containing compounds from triglyceride-containing compositions
The present invention relates to a method for removing phosphorus-containing compounds from triglyceride-containing compositions.
US08987485B2 Method for fractionating Jatropha seeds
A method for the solvent-free fractionation of jatropha seeds having a phorbol ester content and at least one fraction.
US08987484B2 Process for the production of estetrol
The present invention relates to a process for the preparation of a compound of formula (I), hydrates or solvates thereof.
US08987480B2 Process of separating chiral isomers of chroman compounds and their derivatives and precursors
The present invention relates to a process of separating chiral isomers of chroman compounds, particularly tocopherols and tocotrienols as well as the esters and intermediates thereof. It has been found that this process allows a separation of the desired isomer with a higher yield and enables the use of the non-desired isomers in a very efficient way. Said process is particularly useful when implemented in an industrial process. Furthermore, it has been found that this process allows using isomer mixtures as they result from traditional industrial synthesis.
US08987478B2 Process for the preparation of a statin precursor
The present invention relates to a process for the preparation of a precursor for the synthesis of hexanoic acid derived statins and to the use of said precursor in the manufacture of a medicament.
US08987476B2 Spiro epoxides as intermediates
The present disclosure relates to compounds of formula I wherein the substituents are as defined in claim 1. The compounds are suitable intermediates in the preparation of herbicidally active 4-phenyl-3,5-pyrandiones, 4-phenyl-3,5-thiopyrandiones and 6-phenylcyclohexane-1,3,5-triones.
US08987475B2 Process for preparing cyclolignans
The invention relates to a one-pot reaction for the preparation of a compound of Formula (I). The compound of Formula (I) may be further transformed into picropodophyllin and derivatives thereof.
US08987471B2 Substituted dihydropyrazoles as sphingosine receptor modulators
The present invention relates to substituted dihydropyrazoles, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08987464B2 Isoxazoline-substituted benzamide compound and pesticide
An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A1, A2 and A3 independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., W is oxygen atom or sulfur atom, etc., X is halogen atom, C1-C6haloalkyl, etc., Y is halogen atom, C1-C6alkyl, etc., R1 is —CH═NOR1a, —C(O)OR1c, —C(O)NHR1d, phenyl substituted with (Z)p1, D-14, D-52, D-53, D-55 to D-59, etc., R1a is C1-C6alkyl, etc., R1c is C1-C6alkyl, etc., R1d is hydrogen atom, —C(O)R15, —C(O)OR15, etc., R2 is C1-C6alkyl, —CH2R14a, C1-C6alkynyl, —C(O)R15, —C(O)OR15, etc., further when R1 is —CH═NOR1a, —C(O)OR1c or —C(O)N(R1e)R1d, R2 may be hydrogen atom, R3 is C1-C6haloalkyl, etc., R14a is cyano, —OR25, etc., R15 is C1-C6alkyl, C1-C6haloalkyl, C1-C4alkoxy C1-C4alkyl, C1-C4alkylthio C1-C4alkyl, C3-C6cycloalkyl, C2-C6alkenyl, etc., R25 is C1-C4alkyl, C1-C4haloalkyl, —C(O)R32 or —C(O)OR32, etc., R32 is C1-C6alkyl or C3-C6cycloalkyl, etc., Z is halogen atom, cyano, nitro, C1-C6alkyl, C1-C6alkoxy, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.
US08987463B2 Methods of synthesizing factor Xa inhibitors
Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof.
US08987459B2 Compounds for the treatment of conditions associated with DGAT1 activity
The present invention relates to novel crystalline forms of salts of 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans.
US08987458B2 Process for the preparation of donepezil hydrochloride
The present invention provides a process for preparing donepezil or a salt thereof, the process comprising reducing a 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methylene]pyridonium halide of formula II, wherein X is bromide or chloride, in the presence of an ionic compound, a solvent, a catalyst and a source of hydrogen, to form donepezil and optionally converting the donepezil to the salt thereof.
US08987452B2 Synthesis of thiohydantoins
A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.
US08987451B2 Synthesis of cyclometallated platinum(II) complexes
A single-step method of making tetradentate platinum complexes is disclosed. The method advantageously allows the formation of a platinum complex in a single step, even with sterically hindered ligands, without the use of highly reactive intermediates. The compounds made by the disclosed method are useful in OLED applications.
US08987450B2 Luminescent gold(III) compounds for organic light-emitting devices and their preparation
In one embodiment, the present invention provides a class of luminescent gold(III) compounds containing a tridentate ligand with one strong σ-donating group. The present invention also provides methods for synthesizing these compounds, as well as uses of these compounds as electrophosphorescent materials in phosphorescent organic light-emitting devices (OLEDs) to provide electroluminescence (EL).
US08987447B2 Thienopyrazine compound and field effect transistor containing the same
A thienopyrazine compound which is useful for an organic semiconductor material. An organic field effect transistor, which includes an organic semiconductor layer that is easily produced from an organic semiconductor material containing the thienopyrazine compound by a coating method or a printing method, and which exhibits high carrier mobility and high on/off current ratio; and an organic field effect transistor which has ambipolar characteristics. The thienopyrazine compound is represented by chemical formula (I): wherein Ar1 and Ar2 each represents an aryl group, and R1 and R2 each independently represents a hydrogen atom, an alkyl group or an aryl group; or alternatively R1 and R2 represent a group having a ring formed by combining R1 and R2 together.
US08987446B2 Bimetallic complexes and the use thereof in producing diaryl carbonate
The invention relates to bimetallic complexes in which the ligand contains a salophen unit which complexes copper, manganese or cobalt and a phenanthroline unit which complexes palladium and the two systems are linked by a continuous conjugated system. The invention further relates to the use of these bimetallic complexes as catalysts for the oxidative carbonylation of aromatic hydroxy compounds to form diaryl carbonates, a process for preparing diaryl carbonates using the bimetallic complex as catalyst and also diaryl carbonates prepared by oxidative carbonylation of aromatic hydroxy compounds using the bimetallic complexes of the invention as catalysts.
US08987441B2 Substituted polycyclic carbamoyl pyridone derivative prodrug
The present invention provides a compound having antiviral effects, particularly having growth inhibitory activity on influenza viruses, a preferred example of the compound being a substituted 3-hydroxy-4-pyridone derivative prodrug having cap-dependent endonuclease inhibitory activity.
US08987439B2 Three-dimensional structure and method of producing the same
The three-dimensional structure of the present invention is a three-dimensional structure formed on a base. This three-dimensional structure contains a plurality of porphyrins, a plurality of first metal ions, and a plurality of specific organic molecules. The porphyrin contains two or more functional groups. The first metal ion is a metal ion for linking the functional group of one porphyrin to the functional group of another porphyrin. The above specific organic molecule is an organic molecule that forms a coordinate bond with a metal ion contained in the two-dimensional structure and that has only one site to coordinate to the metal ion.
US08987438B2 Method for making derivatized guar gum and derivatized guar gum made thereby
A method for making a derivatized guar, comprising: (a) contacting derivatized guar splits, which have not been treated with a boron compound to crosslink the guar splits, with an aqueous wash medium comprising, based on 100 parts by weight of the aqueous wash medium: (i) from about 0.1 to about 30 parts by weight of a water soluble non-boron salt, or (ii) less than about 0.1 parts by weight water soluble salt, and (b) separating the washed derivatized guar splits from the aqueous wash medium, provided that the contacting of the derivatized guar splits with the aqueous wash medium comprising less than about 0.1 parts by weight water soluble salt is limited to a duration effective to maintain the water content of the washed derivatized guar splits at less than or equal to about 80 percent by weight.
US08987433B2 Variant isoprenoid producing enzymes and uses thereof
This disclosure provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present disclosure provides methods of generating polypeptide variants, for example, variant isoprenoid synthases and/or variant prenyl transferases that have at least one desired property not present in the parent polypeptide. The present disclosure further provides polypeptides and polynucleotides encoding variant polypeptides, as well as vectors and host cells comprising the polynucleotides that encode the variant polypeptides. In other embodiments, the present disclosure provides methods of using the variant polypeptides to generate useful products, such as isoprenoid compounds and/or isoprenoid products.
US08987429B2 GO-Gd-DTPA complex, preparation method thereof, and MRI contrast agent comprising the same
Disclosed herein is a GO-Gd-DTPA (gadolinium-diethylenetriamine pentaacetic-graphene oxide) complex, which is formed by an ester bond of graphene oxide (GO) and gadopentetic acid (Gd-DTPA). Since the GO-Gd-DTPA can stably exist in the body because it has high stability in water, it is expected that it can be effectively used as an MRI contrast agent.
US08987428B2 Lignin-based surfactants
Methods for converting waste streams from the wood pulping industry to high-value surfactants are described. For example, isolated lignin and lignosulfonate or waste streams containing lignin and lignosulfonate can be directly converted to surfactants, or they can be first converted to methylol derivatives and treated with further reagents to produce surfactants.
US08987425B2 Pharmaceutical composition for preventing or treating cancer
The invention provides a fusion protein comprising (a) a first protein comprising a polypeptide which specifically binds to Annexin A1 and (b) a second protein comprising a polypeptide which induces a cytotoxic activity of a cytotoxic lymphocyte, pharmaceutical compositions comprising the fusion protein, and methods of treating or preventing cancer by administering the pharmaceutical compositions.
US08987422B2 CD27L antigen binding proteins
The present invention relates to CD27L antigen binding proteins, such an antibodies, polynucleotides encoding said CD27l antigen binding proteins, antibody drug conjugate compositions, and methods for diagnosing and treating diseases associated with CD27L expression.
US08987416B2 Viral fusion protein treatment for CCR8 mediated diseases
Compositions, methods, and kits are provided for treating CCR8 mediated diseases with applicability to atopic dermatitis and potential applicability to asthma, prurigo nodularis, nummular dermatitis, neurodermatitis, and lichen simplex chronicus and some lymphomas, multiple sclerosis, acquired immunodeficiency disease, peritoneal adhesions, Kaposi's sarcoma and atherogenesis—the expression of all of which, at least in part, is mediated by cells expressing the chemokine receptor CCR8. The compositions include proteins and fusion proteins from Molluscum contagiosum Virus (MCV) or variants, analogs and derivatives thereof which exhibit inhibitory activity. Examples of such MCV proteins are MC148 fusion protein (MC148fp) identified as MC148P-TAT-6×His (“6×His” disclosed as SEQ ID NO: 11), and its variants, fragments, analogs and derivatives which possess inhibitory activity. The variants, fragments, analogs and derivatives of MC148p and of MC148fp may be less than 100% homologous to MCV proteins as long as they are sufficiently homologous that inhibitory activity is preserved.
US08987415B2 Recombinant bacterial lipocalin blc and uses thereof
The present inventors have solved the crystal structure of an Escherichia coli bacterial lipocalin polypeptide, which depicts a monomeric protein. Previous crystal structures have been reported, but these appear to be inaccurate, as they predicted, e.g., a dimeric protein. The crystal structure of a bacterial lipocalin provided by the present invention leads to numerous uses. For example, the present invention provides for the design, construction and use of recombinant libraries of diversified bacterial lipocalins resulting from a bacterial lipocalin polypeptide “backbone”.
US08987408B2 High intrinsic viscosity melt phase polyester polymers with acceptable acetaldehyde generation rates
A method for the production of solid polyester polymer particles comprising: a) polycondensing a molten polyester polymer composition in the presence of a polycondensation catalyst composition comprising antimony species; b) continuing the polycondenzation of the molten polyester polymer composition to an It.V. of 0.68 dL/g or more; and c) after reaching an It.V. of 0.68 dL/g or more, adding a catalyst stabilizer or deactivator to the polymer melt; and d) after reaching an It.V. of 0.68 dL/g or more, solidifying the melt into solid polyester polymer particles which do not contain organic acetaldehyde scavengers. In a further embodiment, after solidification of the polyester from the melt phase polycondenzation process: e) the amount of residual acetaldehyde in the particles in the solid state is reduced to a level of 10 ppm or less without increasing the It.V. of the particles by more than 0.03 dL/g. Such particles having an AA (acetaldehyde) generation rate of 20 ppm or less upon being melted after solidification following the melt phase production and a free AA level reduced after melt phase production to 10 ppm or less are introduced into a melt processing zone to make articles such as bottle preforms having acceptable levels of residual AA.
US08987406B2 Cyclic polyphenylene ether ether ketone composition and method for producing the same
A cyclic poly (phenylene ether ether ketone) composition includes not less than 60% by weight of a cyclic poly (phenylene ether ether ketone) represented by the following Formula (I), which is characterized in that the cyclic poly (phenylene ether ether ketone) is a mixture of cyclic poly (phenylene ether ether ketone)s having different repeating numbers (m) and the composition has a melting point of not higher than 270° C.; and a method of producing a poly (phenylene ether ether ketone) characterized by heat-polymerizing the cyclic poly (phenylene ether ether ketone) composition: where m represents an integer of 2 to 40.
US08987403B2 Amphiphilic polysiloxane prepolymers and uses thereof
The present invention provides an amphiphilic polysiloxane prepolymer which comprises hydrophilic monomeric units derived from at least one hydrophilic vinylic monomer, polysiloxane crosslinking units derived from at least one polysiloxane crosslinker having at least two terminal ethylenically-unsaturated groups, dangling polysiloxane chains each of which is terminated with one ethylenically unsaturated group, and chain-transfer units derived from a chain transfer agent other than a RAFT agent. A prepolymer of the invention is suitable for making hydrogel contact lenses. The present invention is also related to hydrogel contact lenses made from an amphiphilic polysiloxane prepolymer of the invention and to processes for preparing an amphiphilic polysiloxane prepolymer of the invention and for making silicone hydrogel contact lenses.
US08987399B2 Azeotropes of isobutylene with fluoro-olefins
Azeotropic or azeotrope-like compositions of the present invention include trans-1,3,3,3-tetrafluoroprop-1-ene and isobutylene. The azeotropic or azeotrope-like compositions can be used in polymerization processes, including slurry polymerization processes.
US08987396B2 Active polymer polyols and a process for their production
Polymer polyols having a solids content of greater than 40 wt. %, a total ethylene oxide content of up to 25 wt. %, and a viscosity at 25° C. of less than 15,000 centistokes are produced by reacting (1) a base polyol having active hydrogen atoms with an ethylene oxide content of from 15 to 40 wt. % that has been formed in the presence of a double metal cyanide (DMC) catalyst, (2) one or more unsaturated monomers, (3) at least one radical initiator, optionally (4) a preformed stabilizer and optionally (5) a chain transfer agent. These polymer polyols (PMPOs) are useful in the preparation of polyurethane foams and elastomers.
US08987391B2 Polymerization process with in-situ initiator formation
A process for the polymerization of one or more monomers wherein at least one anhydride and at least one peroxy compound selected from inorganic peroxides, organic hydroperoxides, and peroxyacids are dosed during the polymerization reaction in a continuous or intermittent fashion to a reaction mixture comprising said monomers.
US08987388B2 High glass transition temperature resin formulations
A curable resin formulation based on the modification of cyanate esters with silsesquioxane resins is provided for use in forming a cured composite structure or layer. More specifically, a resin formulation that generally comprises a silsesquioxane resin component having an equivalent weight of aromatic hydroxyl groups that is greater than 500 and less than 2,000 grams per mole of aromatic hydroxyl groups; a cyanate ester component; and optionally a catalyst is described. In this resin formulation, the silsesquioxane resin component is present in an amount greater than 10 wt. % of the total solids content of the resin formulation. The resin composite layer formed therefrom exhibits a glass transition temperature that is greater than or equal to 185° C., wherein this glass transition temperature decreases by less than or equal to 40% upon exposure to water at an elevated temperature for a predetermined amount of time.
US08987387B2 Interfacial polymer for rubber-silica network
Disclosed is an interfacial polymer for a network used as a coupling agent in mixing of rubber-silica. More particularly, the interfacial polymer for a rubber-silica network is a block copolymer containing a copolymer of conjugated diene and vinyl aromatic monomers, in which when used as a coupling agent in the mixing of synthetic rubber and silica (an inorganic material), the polymer enhances silica dispersibility within the rubber, and improves compatibility and processability, resulting in considerable improvement in the dynamic property as well as the mechanical property of the rubber, and when used in a tire, etc., it enhances automobile braking performance and reduces rolling resistance.
US08987382B2 High melt strength polyethylene compositions and methods for making the same
The present invention is a method for increasing the melt strength of a polyethylene resin comprising reacting the polyethylene resin with a free radical generator with a decomposition energy in between −50 kJoule/mole and −250 kJoules/mole and a peak decomposition temperature of less than 280 degree C. The resulting resin has increased melt strength with higher ratio of elongational viscosities at 0.1 to 100 rad/s when compared to substantially similar polyethylene resins which have not been reacted with a free radical generator such as an alkoxy amine derivative.
US08987380B2 Functional materials with controllable viscosity
The present invention relates to an innovative method for controlling the viscosity of, for example, adhesives or coating formulations. The method for controlling viscosity allows very rapid thermoplastic curing of a formulation even at room temperature and a significant reduction in the viscosity at higher temperatures, thereby regaining the capacity for simple processing and allowing, for example, the originally bonded substrates to be separated from one another again with ease. A particular aspect in this context is that a plurality of cycles of thermoplastic curing and a significant reduction in the viscosity are possible with the present system.
US08987369B2 Acrylic acid polymer nanocomposites from aminosilane-modified colloidal silica
This invention relates to compositions comprising blends of acrylic add polymers and/or ethylene acrylic add copolymers and colloidal silica modified with certain aromatic aminosilanes, aromatic aminoalkylsilanes, alkenyl aminoalkylsilanes, secondary or tertiary aliphatic aminosilanes. These compositions can provide improved properties such loss modulus, storage modulus, creep resistance, and wear resistance, without sacrificing optical clarity.
US08987368B2 Polymers based on grafted polyolefins
The present invention relates to a polymer (P1) obtainable by reaction of at least one component a) with at least one component b), wherein a) is at least one polyolefin (A), which is grafted with at least one compound (G), and b) is at least one compound (B) containing at least two epoxy groups.
US08987362B2 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents
In general the present invention provides a functionalized polymer prepared by a process comprising the steps of preparing a pseudo-living polymer by polymerizing conjugated monomer with a lanthanide-based catalyst, and reacting the pseudo-living polymer with a functionalizing agent defined by the formula (I) A-R1—Z  (I) where R1 is a divalent bond or divalent organic group comprising from 0 to about 20 carbon atoms, A is a substituent that will undergo an addition reaction with a pseudo-living polymer, and Z is a substituent that will react or interact with silica or carbon black reinforcing fillers, with the proviso that A, R1, and Z are substituents that will not protonate a pseudo-living polymer.
US08987357B2 Thermoplastic molding composition
The present invention relates to a thermoplastic molding composition comprising the following components: A) 20 to 98.99% by weight of at least one polyamide, B) 0.01 to 40% by weight of at least one branched polyimide selected from condensates of either b1) at least one polyisocyanate having an average of more than two isocyanate groups per molecule or b2) at least one polyamine having an average of more than two amino groups per molecule and b3) at least one polycarboxylic acid having at least three COOH groups per molecule or its anhydride C) 1 to 59% by weight of at least one flame retardant selected from the group of c1) phosphorus-containing flame retardants c2) nitrogen-containing flame retardants and mixtures of these, D) 0 to 50% by weight of further additives, where the total of the proportions by weight is 100% by weight based on the molding composition.
US08987356B1 Flexible polymer concrete and methods for making flexible polymer concrete
A composition that sets to produce a concrete includes Portland cement; a polymerizable material having bubbles dispersed in the polymerizable material; an aggregate; and water in a sufficient amount such that the composition sets to a concrete. A method for making a concrete article uses a paste that includes Portland cement and a polymerizable material having bubbles dispersed in the polymerizable material. The paste is added to an aggregate to create a settable composition, and the settable composition is allowed to set to a concrete article.
US08987354B2 Biocompatible polymer nanoparticle coating composition and method of production thereof
Biocompatible polymeric coating compositions having nanoscale surface roughness and methods of forming such coatings are described. A polymeric biocompatible coating may be produced using a powder coating method, where one or more thermosetting polymer resins and one or more biocompatible materials are mixed and extruded, ground into microscale particles, and mixed with nanoparticles to form a dry powder mixture that may be coated onto a substrate according to a powder coating method. Alternatively, the thermosetting polymeric resin can be first extruded and ground into microscale particles, and then mixed with the biocompatible materials in particular form of nanoscale to microscale in size, and then further mixed with nanoparticles to form a dry powder mixture for coating. Bioactive materials may also be selectively added into the polymeric coating in a similar way as the biocompatible materials, either before or after the extrusion, to form a bioactive polymeric coating.
US08987352B1 Phase separated self-healing polymer coatings
Phase separated self-healing polymer coatings having a “biphasic” thermoset/thermoplastic morphology to achieve self-healing. The biphasic structure has: (i) a major “load-bearing” thermoset phase that has superior strength and performs major mechanical and structural functions, and (ii) a “self-healing” phase of a thermoplastic healing agent to repair the material and restore its mechanical and structural integrity after being damaged. The phase-separated morphology is achieved through phase separation via a reaction process.
US08987345B2 Dental bonding agent and coating agent
The present disclosure provides a dental bonding agent which may comprise a composite resin containing an ingredient selected from acrylic resins, a primer comprising an amphiphile, and at least one phosphate ester, and a solvent. The dental bonding agent may be applied for resin restoration, prosthetic adhesion, enhancing adhesive strength between dentin and artificial post, and tooth coating. The present disclosure also provides a coating agent which may comprise a dental bonding agent as defined above, a pigment, and an inorganic filler.
US08987342B2 Photosensitive resin composition for insulating film of display device, insulating film using the same, and display device using the same
A photosensitive resin composition for an insulating film of a display device includes (A) an alkali soluble resin including a polybenzoxazole precursor, polyamic acid, polyimide, or a combination thereof; (B) a photosensitive diazoquinone compound; (C) an ultraviolet (UV) absorber having a maximum absorption wavelength of about 300 to about 400 nm; and (D) a solvent. An insulating film and a display device can include the photosensitive resin composition.
US08987340B2 Sublimable sustained release delivery system and method of making same
The invention relates to compositions suitable for the delivery and/or stabilization of biologically active substances. The compositions comprise a sublimable matrix material and the biologically active agent to be delivered. The compositions can be used as drug delivery systems to treat a wide variety of diseases or as systems for the protection and stabilization of such substances. Also disclosed are methods for preparing compositions of the present invention.
US08987331B2 Two-part disinfectant system and related methods
The present disclosure is drawn to a disinfectant system which can be used to disinfect surfaces. The system includes a first chamber containing a first solution and a second chamber containing a second solution. The first solution can include an alcohol, an organic carboxylic acid, and from 0.01 ppm, to 1,000 ppm by weight of a transition metal or alloy thereof based on the first solution weight content. The second solution can include hydrogen peroxide. The system further includes a dispenser through which the system is configured to mix and dispense the first solution and the second solution immediately before being dispensed. A peracid composition is formed upon mixing of the first and second solutions.
US08987330B2 Pharmaceutical composition for the treatment of fungal infections
There is provided pharmaceutical compositions suitable for topical application to the nail for the treatment of nail diseases such as onychomycosis, comprising a urea-based component, a diol component, such as propylene glycol, an organic acid component, such as lactic acid, and a triol component, such a glycerol. There is further provided methods of improving the storage stability of a pharmaceutical composition suitable for topical application to the skin and/or nails comprising such urea-based components, diol components, organic acid components, and, optionally, an aqueous base, which method comprises adding a triol component, such a glycerol, to that composition prior to said storage.
US08987327B1 Kits and methods for treating post traumatic stress disorder (PTSD) and hot flashes
The present invention is directed to kits and methods for the treatment of a patient suffering from post-traumatic stress disorder (PTSD) and/or hot flashes by an administration of a mixture produced by a combination of a long acting local anesthetic combined with clonidine. The combination of the two pharmaceuticals produces a significant increase in duration and speed of onset of sympathetic blockade, increased intensity of the sympathetic blockage as well as the reduction of local anesthetic absorption locally. The combination significantly improves the efficacy, speed of onset and block intensity of a right sided cervical sympathetic ganglion injection (RCSGI) leading to increased length of resolution of PTSD and hot flashes as well as reducing the potential for complications related to absorption of the local anesthetic.
US08987324B2 Use of simalikalactone E as an anticancer agent
The invention relates to Simalikalactone E (SkE) to be used for preventing and/or treating cancers.
US08987322B2 Pharmaceutical formulations for carrier-mediated transport statins and uses thereof
The present invention relates to formulations comprising therapeutically effective amounts of at least one acid-stable, carrier-mediated transport statin, at least one poorly water-soluble, carrier-mediated transport statin, or at least one large molecular weight, carrier-mediated transport statin, such as atorvastatin and rosuvastatin, or a pharmaceutically acceptable salt thereof, and methods of their use. The present formulations and methods are designed to exhibit a controlled-release of a therapeutic amount of the statin in the small intestine, thereby limiting systemic exposure of the statin and maximizing liver-specific absorption of the drug. The formulations and methods of the present invention are particularly useful for treating and/or preventing conditions that are benefited by decreasing levels of lipids and/or cholesterol in the body.
US08987321B2 Lisofylline analogs and methods for use
The present invention provides analogs of a Lysofylline (LSF), and synthetic methods for the preparation of such analogs. The have the active side chain moiety (5-R-hydroxyhexyl) of LSF and can have greater potency and oral bioavailability than LSF.
US08987318B2 Liver X receptor (LXR) modulators for the treatment of dermal diseases, disorders and conditions
Described herein are liver X receptor (LXR) modulators and methods of utilizing LXR modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
US08987316B2 Isocyanate and isothiocyanate compounds for cancer treatment
The present invention relates to novel isocyanate and isothiocyanate compounds, to pharmaceutical compositions comprising them, and to the use thereof in the treatment of cancer diseases in humans and animals. The novel isocyanate and isothiocyanate compounds are distinguished, as compared with the known isocyanate and isothiocyanate compounds, by improved therapeutical breadth, i.e. fewer side effects while having high anti-tumor activity.
US08987313B2 Inhibitors of cytochrome P450
The present application provides for a compound of formula I, or a salt thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional therapeutic agent.
US08987311B2 Triazolyl-substituted pyridyl compounds useful as kinase inhibitors
Compounds having the following formula: (I) wherein: A is an optionally substituted triazole, or a stereoisomer or a pharmaceutically-acceptable salt thereof, are useful as kinase modulators, including IRAK-4 modulation.
US08987308B2 Compounds for the treatment of Clostridium difficile-associated disease
Disclosed are compounds of formula (I): or a pharmaceutically acceptable N-oxide, salt, hydrate, solvate, complex, bioisostere, metabolite or prodrug thereof, which are of use in the treatment of infection with, and diseases caused by, Clostridium difficile.
US08987307B2 3-amino-pyridines as GPBAR1 agonists
This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
US08987299B2 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity
Compounds of formula (I) described herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.
US08987297B2 Nitrogen containing compounds
Compounds of Formula (I), their preparation and use in preventing or treating bacterial infection is disclosed.
US08987296B2 Acridone compounds
A class of acridone compounds has been discovered that exhibits chemosensitizing and antiparasitic activity. Described herein are pharmaceutical compositions and methods for their use to treat parasitic infections, such as malaria and toxoplasmosis, and to sensitize resistant cells, such as multidrug resistant cells to other therapeutic agents. The pharmaceutical compositions and methods may also be used to treat and/or prevent psychotic diseases such as schizophrenia.
US08987294B2 Small molecule inhibitors of the α4-paxillin interaction
The present invention is directed to novel compounds that are able to inhibit the interaction of paxillin or its paralogues, including leupaxin or Hic-5, with alpha.4 integrin or its binding partners that regulate signaling events downstream of the paxillin-.alpha.4 interaction. The present invention further relates to methods for therapeutic use of such compounds and pharmaceutical compositions of such compounds for the treatment of a disease or condition.
US08987290B2 Use of opioid formulations in needle-less drug delivery devices
The present invention concerns a needle-less drug delivery device being suitable for delivering drugs through a skin surface into a human or animal body comprising a pharmaceutical composition with at least one analgesic agent preferably being an opioid. The present invention also relates to the use of at least one analgesic agent, preferably being at least one opioid in a needle-less drug delivery device being suitable for injecting medication through a skin surface into the human or animal body. Further, the invention is concerned with a method of treating breakthrough pain by injecting at least one analgesic agent preferably being an opioid into the human or animal body using a needle-less drug delivery device.
US08987289B2 Methods for treating pruritus
The present invention relates to methods for treating pruritus with anti-pruritic compositions.
US08987283B2 Pyrrolo[2,3-D]pyrimidine compounds
Described herein is pyrrolo{2,3-d}pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing this compounds, and methods for the preparation of these compounds.
US08987282B2 Acyclovir and meloxicam combination therapy for functional somatic syndromes
The present invention relates to pharmaceutical compositions comprising a combination of a therapeutically-effective amount of the antiviral compound acyclovir and a therapeutically-effective amount of the COX-2 inhibitor meloxicam. The invention is further related to methods of treating functional somatic syndromes by administering a therapeutically-effective combination of acyclovir and meloxicam.
US08987281B2 Methods of treating cancer
Described are methods and compositions for treating epithelial tumors with a folate-vinca conjugate in combination with at least one other chemotherapeutic agent in which the tumors include ovarian, endometrial or non-small cell lung cancer tumors, including platinum-resistant ovarian tumors and platinum-sensitive ovarian tumors.
US08987277B2 Fungicide
The invention relates to fungicides and can be used for treating diseases caused by fungi, and also for preventing damage to various materials and agricultural products by fungi. The fungicide is a 2,4-dioxo-5-(2-hydroxy-3,5-dichlorobenzylidiene)amino-1,3-pyrimidine salt of general formula: (A) or a dimer thereof: (B), where X is selected from the series consisting of: Na+, K+, Li+ and NH4+. An effective preparation having anti-fungal activity with a broad spectrum of action is created.
US08987274B2 Macrocycles that increase p53 activity and the uses thereof
The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
US08987273B2 Substituted imidazo[1,2-B]pyridazines
The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacture and their use for the treatment of benign and malignant neoplasia.
US08987271B2 2,2′-biphenazine compounds and methods useful for treating disease
The invention relates to a chemotherapeutic cancer treatment in which compounds (BH3Is) are administered to a mammal to treat B-cell Lymphoma or other hematopoietic cancers, including diseases associated with MCL-1. The invention also provides a method for treating types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more disclosed compounds in combination with other therapies, for example, 26S proteosome inhibitors, such as, for example, Bortezomib. The invention also relates to autoimmune treatment with pharmaceutical compositions comprising one or more disclosed compounds. The invention also relates to methods for identifying compounds, for example, compounds of the BH3 mimic class, that have unique in vitro properties that predict in vivo efficacy against B-cell lymphoma tumors and other cancers as well as autoimmune disease. Illustrative compounds are those of Formula II:
US08987269B2 Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor
Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.
US08987268B2 Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.
US08987265B2 Substituted 1,3,5-triazine derivatives of fused bicyclic oxalamide compounds for treatment of Hepatitis C
Compounds of Formula I, including pharmaceutically acceptable salts thereof, as well as compositions containing these compounds, have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV:
US08987263B2 Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents
Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
US08987260B2 Pharmaceutical compounds
Provided herein is a pharmaceutical composition that comprises a pharmaceutically acceptable carrier or diluent and, as an active ingredient, the compound 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine bismesylate.
US08987252B2 Aryloxy- and heteroaryloxy-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
The aryloxy- and heteroaryloxy-substituted tetrahydrobenzazepine derivative compounds of the present invention are represented by formulae (I) (A-E) having the following structure where the carbon atom designated * is in the R or S configuration and the substituents X and R1—R9 are as defined herein.
US08987249B2 Substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C
This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
US08987248B2 Substituted piperidines as Par-1 antagonists
The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumor disorders.
US08987243B2 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-maleate salt
The present invention relates to certain salts of a 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26triaza-tetra-cyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (Compound I) which have been found to have improved properties. In particular the present invention relates to the maleate salt of this compound. The invention also relates to pharmaceutical compositions containing this salt and methods of use of the salt in the treatment of certain medical conditions.
US08987242B2 Morpholinone compounds as factor IXA inhibitors
The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
US08987241B2 Time-release and micro-dose formulations for topical application of estrogen and estrogen analogs or other estrogen receptor modulators in the treatment of dry eye syndrome, and methods of preparation and application
A topical application formulation of estrogen and estrogen analogs or other estrogen receptor modulators is disclosed for the treatment of primary or secondary dry eye syndrome (also known as keratoconjunctivitis sicca (KCS)). Preferred formulations include 17-β-estradiol and its derivatives in lipid, liposomes, polymers, or aqueous or non-aqueous vehicles for the topical treatment of the ocular surface tissues particularly as time-release or micro-dose formulations. These formulations may also be useful in treating other conditions where KCS may occur, such as post-operative refractive surgery and corneal transplant patients.
US08987231B2 Sulodexide for use in the treatment of pathologies wherein metalloproteinases are involved
The present invention describes sulodexide or at least one of its components for use in the reduction of circulating matrix metalloproteinase (MMPs), in particular MMP-9. Sulodexide and its composition are useful for the treatment of pathologies wherein the MMPs are involved, such as cardiovascular disease, cardiovascular disease caused by diabetes, varicose veins, chronic venous insufficiency (CVI), gastrointestinal ulcers, pulmonary disease, and neoplastic pathologies.
US08987230B2 Hybrid gel comprising chemically crosslinked hyaluronic acid derivative and pharmaceutical composition comprising the same
The present invention provides a composition comprising a hyaluronic acid derivative having a crosslinking group(s) and a hydrophilic polysaccharide derivative having a hydrophobic group(s), wherein the hyaluronic acid derivative having a crosslinking group(s) is prepared by crosslinkage formation reaction in hyaluronic acid or a derivative thereof having a crosslinkable group(s) in the presence of the hydrophilic polysaccharide derivative wherein the hydrophilic polysaccharide derivative may have a crosslinkable group(s).
US08987229B2 Semi-fluid food product comprising beta-glucan fibres
The present invention relates to a semi-fluid thermized aqueous solution comprising β-glucan fibers and a sufficient amount of at least one viscosity depressant chosen from the group composed of maltodextrins having a maximum DE of 18, at least partially hydrolyzed guar gum, inulin and fructooligosaccharides. Another subject of the invention is a process for preparing such a thermized aqueous solution comprising a step of slowly cooling a thermized dispersion comprising water, at least one viscosity depressant and β-glucan fibers, under shear. The invention lastly relates to the use of such a thermized aqueous solution in a food product.
US08987228B2 Pharmaceutical composition including an A3 adenosine receptor agonist 1-deooxy-1-[N6-(3-idobenzyl)-adenin-9-yl]-N-methyl-β-D-ribofuronamide(IB-MECA/CF-101) for treatment of psoriasis
Clinical finding shows that twice daily administrations of 2 mg of 1-deoxy-1-[N6-(3-iodobenzyl)-adenin-9-yl]-N-methyl-β-D-ribofuronamide (IB-MECA) (total daily administration of 4 mg) to subjects having moderate to severe psoriasis, was significantly more effective in treatment of the psoriatic plaques than treatment of psoriasis at two administration doses of 1 mg or 4 mg (total daily doses of 2 or 8 mg, respectively). A pharmaceutical composition for the treatment of psoriasis includes as the active ingredient IB-MECA in an amount suitable for a total daily dose administration of about 4 mg. In one preferred embodiment, IB-MECA is administered twice a day to a subject in need of psoriasis treatment, the pharmaceutical composition including an administration dose of 2 mg.
US08987227B2 Hepatitis C dsRNA effector molecules, expression constructs, compositions, and methods of use
The present invention provides agents, compositions, constructs and methods for silencing HCV polynucleotides, as well as methods and compositions for treating or preventing HCV infection in a mammalian cell. In one aspect, the present invention provides an agent or composition comprising at least one double-stranded RNA effector molecule or complex. The double-stranded RNA effector molecule or complex comprises: (1) a sequence of at least 19 nucleotides having at least 90% identity with a nucleotide sequence within HCV Conserved Region 1 (SEQ ID NO: 2), HCV Conserved Region 2 (SEQ ID NO: 3), HCV Conserved Region 5 (SEQ ID NO: 4), (ATR)-1 (SEQ ID NO: 86), ATR-2 (SEQ ID NO: 87), ATR-3 (SEQ ID NO: 88), ATR-4 (SEQ ID NO: 89); and (2) its complementary sequence. In another aspect, the present invention provides a construct suitable for replication in a host cell, and/or suitable for expression of an RNA molecule or complex of the invention in vitro or in vivo. In a third aspect, the present invention provides a method for silencing HCV RNA in a mammalian cell, which comprises administering to the mammalian cell an agent, composition, or construct of the invention in a manner and amount effective to silence HCV RNA in the cell. In a related aspect, the invention provides a method for treating or preventing HCV infection in a patient, comprising administering to the patient an effective amount of an agent, composition, or construct of the invention as described herein.
US08987226B2 Modified single-stranded polynucleotides
It is intended to provide a polynucleotide that is resistant to RNase and has an RNA interference effect, etc. The present invention provides a single-stranded polynucleotide that is derived from a double-stranded polynucleotide comprising a sense strand polynucleotide corresponding to a target gene, and an antisense strand polynucleotide having a nucleotide sequence complementary to the sense strand polynucleotide, and has a structure in which the 5′-end of the antisense strand and the 3′-end of the sense strand are linked via a phenyl group-containing linker to form a phosphodiester structure at each of these ends.
US08987223B2 Treatment of pulmonary and pleural fibrosis using HSP27 inhibitors
Reduction of HSP27 expression is in beneficial in the treatment of pleural and pulmonary fibrosis and in particular subpleural fibrosis and IPF. Pharmaceutical compositions for this purpose contain an inhibitor of HSP27 and a pharmaceutically acceptable carrier.
US08987217B2 Modified saponins for the treatment of fungal infections
Methods of treating a fungal infection in a subject, the method comprising administering to the subject a modified saponin.
US08987216B2 Polysulfated glycosides and salts thereof
The invention relates to polysulfated glycosides of formula (I), the pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions containing these compounds as active ingredients. Furthermore the invention provides a method of preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders of the airways of mammals—including asthma and asthma-related pathologies.
US08987213B2 Peptides that selectively home to heart vasculature and related conjugates and methods
The present invention provides a variety of isolated peptides and peptidomimetics, which can be useful, for example, in constructing the conjugates of the invention or, where the peptide itself has biological activity, in unconjugated form as a therapeutic for treating any of a variety of cardiovascular diseases as described below. Thus, the present invention provides an isolated peptide or peptidomimetic which has a length of less than 60 residues and includes the amino acid sequence CRPPR (SEQ ID NO: 1) or a peptidomimetic thereof. The invention further provides an isolated peptide or peptidomimetic which has a length of less than 60 residues and includes the amino acid sequence CARPAR (SEQ ID NO: 5) or a peptidomimetic thereof, or amino acid sequence CPKRPR (SEQ ID NO: 6) or a peptidomimetic thereof.
US08987210B2 Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof
This application is directed to chemokine-immunoglobulin fusion polypeptides and chemokine-polymer conjugates. The fusion polypeptides and conjugates can be used for treating chemokine receptor-mediated disorders and modulating inflammation, inflammatory cell motility, cancer cell motility, or cancer cell survival.
US08987207B2 Peptides which have analgesic effects and which inhibit ASIC channels
Novel isolated peptides which induce analgesia and which inhibit ASIC channels (Acid Sensing Ion Channels), to the polynucleotides encoding these peptides, and also to the pharmaceutical compositions, host cells, and vectors comprising these peptides and the polynucleotides encoding these peptides. In particular, these peptides are isolated from the venom of the snake Dendroaspis polylepis. The present invention also relates to the use of these peptides as a diagnostic tool or as a medicament, particularly as an analgesic, or for identifying analgesic molecules or molecules which inhibit ASIC channels.
US08987202B2 Factor VII or Factor VIIa Gla domain variants
Gla domain variants of human Factor VII or human Factor VIIa, comprising 1-15 amino acid modifications relative to the human Factor VII or human Factor VIIa sequence shown in SEQ ID NO:1, wherein a hydrophobic amino acid residue has been introduced by substitution in position 34; or having an amino acid substitution in position 36; and use of the variants for the treatment of intracerebral haemorrhage (ICH) or trauma.
US08987195B2 HCV NS3 protease inhibitors
The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.
US08987192B2 Potent and selective mediators of cholesterol efflux
The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and having high selectivity for ABAC1 that parallels that of full-length apolipoproteins. The invention also provides compositions comprising such polypeptides, methods of identifying, screening and synthesizing such polypeptides, and methods of treating, preventing or diagnosing diseases and disorders associated with dyslipidemia, hypercholesterolemia and inflammation.
US08987191B2 Bioactive peptides and methods of using same
Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
US08987189B2 Treating hepatitis C virus infection
Methods and compositions are provided to inhibit release of HCV from an HCV-infected cell by contacting the cell with a VLDL assembly inhibitor, and detecting a resultant inhibition of HCV release from the cell. The methods can be used to decrease serum viremia of an HCV-infected person.
US08987185B2 Laundry article having cleaning and conditioning properties
The invention discloses a laundry article used for both cleaning and conditioning fabrics comprising a water-insoluble nonwoven substrate and coated thereon into at least one zone each a detergent composition and a fabric conditioning composition. The fabric conditioning composition comprises a quaternary ammonium cationic surfactant, an alkoxylated fatty alcohol and a fatty acid.
US08987179B2 Compositions containing secondary paraffin sulfonate and alcohol alkoxylate
The invention relates to compositions containing a) 45 to 65 wt. % of one or more secondary paraffin sulfonates with 8 to 22 carbon atoms, b) 1 to 10 wt. % of one or more alcohol alkoxylates which are produced from the reaction of alcohols R—OH, wherein R is an alkyl group with 4 to 8 carbon atoms, with alkoxylating agents selected from ethylene oxide, propylene oxide, or mixtures thereof and which contain on average 1 to 10 mol of structural units derived from the alkoxylating agents per 1 mol of structural units derived from the alcohols, and c) 25 to 52 wt. % water, in relation to the total weight of the composition in each case. The compositions can be used in an advantageous manner for producing washing and cleaning agents.
US08987177B2 Biodegradable lubricant composition
A biodegradable lubricating oil composition includes (A) an ester being obtained by reacting a saturated aliphatic carboxylic acid, a straight-chain aliphatic dicarboxylic acid and a polyhydric alcohol together, the ester having a kinematic viscosity in a range from 400 mm2/s to 1000 mm2/s at 40 degrees C. and an acid value of 0.5 mgKOH/g or less; (B) an ester being obtained by reacting a straight-chain saturated aliphatic carboxylic acid with a polyhydric alcohol, the ester having an acid value of 0.5 mgKOH/g or less; and (C) a phosphate amine salt being obtained by reacting an acidic phosphate with an alkylamine.
US08987173B2 Compositions and methods for monitoring and altering protein folding and solubility
The present invention relates to the fields of microbiology, molecular biology and protein biochemistry. More particularly, it relates to compositions and methods for analyzing and altering (e.g., enhancing or inhibiting) protein folding and solubility.
US08987171B2 Selective herbicides with activator adjuvants
An environmentally compatible, selective herbicidal composition is provided that includes an activator adjuvant for enhancing the efficacy of the composition. While the activator adjuvant can be used in combination with a variety of herbicides, in an exemplary embodiment the herbicidal composition includes a metal chelate that is formed from a transition metal component and at least one chelating agent. The activator adjuvant can enhance, even synergistically effect the efficacy of the composition, while maintaining the selectivity of the herbicide.
US08987167B2 Low volatile amine salts of anionic pesticides
The present invention relates to a salt comprising an anionic pesticide and a cationic polyamine of the formula (A) or (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt. It also relates to a method for preparing said salt comprising combining the pesticide in its neutral form or as salt, and the polyamine in its neutral form or as salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi. It also relates to a method of controlling undesired vegetation. Finally, the invention relates to seed comprising said salt.
US08987166B2 Preparation of cerium oxide-supported nano gold-silver catalysts and its application in carbon monoxide removal in air
The preparation of bimetallic gold-silver cerium dioxide-supported catalysts and the process of oxidation of carbon monoxide (CO) in air to remove CO using the gold-silver cerium dioxide-supported catalysts are disclosed. The gold loading is between 0.5 and 5 wt. %. Gold and silver particle sizes are between 1 and 3 nm, and Au/Ag weight ratio is between 1 and 10. Oxidation of CO in air over these catalysts is carried out in a fixed bed reactor to remove CO.
US08987162B2 Hydrothermally stable, low-temperature NOx reduction NH3-SCR catalyst
A catalyst composition includes a heterobimetallic zeolite characterized by a chabazite structure loaded with copper ions and at least one trivalent metal ion other than Al3+. The catalyst composition decreases NOx emissions in diesel exhaust and is suitable for operation in a catalytic converter.
US08987160B2 Fischer-tropsch catalysts containing iron or cobalt selective towards higher hydrocarbons
Cryptomelane-type manganese oxide octahedral molecular sieves (OMS-2) supported Fe and Co catalysts are utilized in a method for producing hydrocarbons by a Fischer-Tropsch mechanism. The hydrocarbon producing method includes providing a catalyst of a manganese oxide-based octahedral molecular sieve nanofibers with an active catalyst component of at least one of iron, cobalt, nickel, copper, manganese, vanadium, zinc, and mixtures thereof, and further containing an alkali metal. The formation of iron carbides and cobalt carbides by exposing the catalyst to conditions sufficient to form those carbides is also taught. After the catalyst has been appropriately treated, a carbon source and a hydrogen source are provided and contacted with the catalyst to thereby form a hydrocarbon containing product. The catalyst have high catalytic activity and selectivity (75%) for C2+ hydrocarbons in both CO hydrogenation and CO2 hydrogenation. Highly selective syntheses of high value jet fuel, C2-C6 alkenes, C2-C6 carboxylic acids; α-hydroxylic acids and their derivatives have been realized by tuning the oxidation ability of OMS-2 supports and by doping with Cu2+ ions.
US08987154B2 Modulus, lithium free glass
An R-glass composition including SiO2 in an amount from 59.0 to 64.5% by weight, Al2O3 in an amount from 14.5 to 20.5% by weight, CaO in an amount from 11.0 to 16.0% by weight, MgO in an amount from 5.5 to 11.5% by weight, Na2O in N an amount from 0.0 to 4.0% by weight, TiO2 in an amount from 0.0 to 2.0% by weight, Fe2O3 in an amount from 0.0 to 1.0% by weight, B2O3 in an amount from 0.0 to about 3.0% by weight, K2O, Fe2O3, ZrO2, and Fluorine, each of which is present in an amount from 0.0 to about 1.0% by weight, and SrO and ZnO, each of which is present in an amount from 0.0 to about 2.0% by weight. In exemplary embodiments, the glass composition does not contain lithium or boron.
US08987149B2 Fire resistant composite material and fabrics made therefrom
The present invention relates to fire resistant composite materials and to fire resistant fabric materials and mattresses made therefrom. The composite materials include (a) a substrate selected from the group consisting of cotton, rayon, lyocell and blends thereof; and (b) a coating consisting essentially of water, ammonium polyphosphate, binder material, cross-linking material, thickener material and a catalyst. The binder material bonds the ammonium polyphosphate, cross-linking material, thickener material and catalyst together and to the substrate such that the substrate is coated with the coating.
US08987148B2 Semiconductor device manufacturing method
With a stage kept in an as-heated state, a semiconductor wafer is placed over the stage. Then, with the elapse of a first time, a controller causes a pressure inside a vacuum chamber to rise to a second pressure higher than a first pressure (step S40). After the semiconductor wafer is placed over the stage, a pressure difference between a pressure inside the vacuum chamber and a pressure inside an adsorption port is set to a minimum value at which the semiconductor wafer is not allowed to slide over protrusions. Further, in step S40 as well, the pressure difference is kept at the minimum value at which the semiconductor wafer is not allowed to slide over the protrusions.
US08987147B2 Method of depositing a film using a turntable apparatus
A method of depositing a film on substrates using an apparatus including a turntable mounting substrates, first and second process areas above the upper surface of the turntable provided with gas supplying portions, a separation gas supplying portion between the first and second process areas, and a separation area including depositing a first oxide film by rotating the turntable first turns while supplying a first reaction gas, the oxidation gas from the second gas supplying portion, and the separation gas; rotating at least one turn while supplying the separation gas from the first gas supplying portion and the separation gas supplying portion, and the oxidation gas from the second gas supplying portion; and rotating at least second turns to deposit a second oxide film while supplying a second reaction gas from the first gas supplying portion, the oxidation gas from the second gas supplying portion, and the separation gas.
US08987145B2 Semiconductor device, manufacturing method of the semiconductor device
A two-layered polysilicon capacitive element is manufactured to enable suppression of both of an increase in the applied electric field dependence of the capacitance value and the initial defect of the dielectric film. Included are a lower electrode into which phosphorous ions are implanted, a dielectric film formed on the lower electrode, and an upper electrode formed on the dielectric film. The dielectric film includes a thermal oxide film formed by partially oxidizing a polysilicon film constituting the lower electrode and etching out its outer layer part, and a deposited oxide film formed on the thermal oxide film.
US08987144B2 High-K metal gate electrode structures formed by cap layer removal without sacrificial spacer
In sophisticated semiconductor devices, high-k metal gate electrode structures may be formed in an early manufacturing stage with superior integrity of sensitive gate materials by providing an additional liner material after the selective deposition of a strain-inducing semiconductor material in selected active regions. Moreover, the dielectric cap materials of the gate electrode structures may be removed on the basis of a process flow that significantly reduces the degree of material erosion in isolation regions and active regions by avoiding the patterning and removal of any sacrificial oxide spacers.
US08987143B2 Hydrogen plasma cleaning of germanium oxide surfaces
Methods and apparatus for processing using a remote plasma source are disclosed. The apparatus includes an outer chamber enclosing a substrate support, a remote plasma source, and a showerhead. A substrate heater can be mounted in the substrate support. A transport system moves the substrate support and is capable of positioning the substrate. The plasma system may be used to generate activated hydrogen species. The activated hydrogen species can be used to etch/clean semiconductor oxide surfaces such as silicon oxide or germanium oxide.
US08987138B2 Nonvolatile memory device using semiconductor nanocrystals and method of forming same
A method of making a nanoparticle array that includes replicating a dimension of a self-assembled film into a dielectric film, to form a porous dielectric film, conformally depositing a material over the said porous dielectric film, and anisotropically and selectively etching the deposited material.
US08987129B2 Group V doping of GaAs-based layers to improve radiation tolerance of solar cells
Methods for improving the performance and lifetime of irradiated photovoltaic cells are disclosed, whereby Group-V elements, and preferably nitrogen, are used to dope semiconductor GaAs-based subcell alloys.
US08987128B2 Cross-coupling based design using diffusion contact structures
An approach for providing cross-coupling-based designs using diffusion contact structures is disclosed. Embodiments include providing first and second gate structures over a substrate; providing a first gate cut region across the first gate structure, and a second gate cut region across the second gate structure; providing a first gate contact over the first gate structure, and a second gate contact over the second gate structure; and providing a diffusion contact structure between the first and second gate cut regions to couple the first gate contact to the second gate contact.
US08987123B2 Heat treatment apparatus and heat treatment method for heating substrate by irradiating substrate with flash of light
After the completion of the transport of a semiconductor wafer into a chamber, the flow rate of nitrogen gas supplied into the chamber is decreased. In this state, a preheating treatment and flash irradiation are performed. The flow rate of nitrogen gas supplied into the chamber is increased when the temperature of the front surface of the semiconductor wafer is decreased to become equal to the temperature of the back surface thereof after reaching its maximum temperature by the irradiation of the substrate with a flash of light. Thereafter, the supply flow rate of nitrogen gas is maintained at a constant value until the semiconductor wafer is transported out of the chamber. This achieves the reduction in particles deposited on the semiconductor wafer while suppressing adverse effects resulting from the nonuniform in-plane temperature distribution of the semiconductor wafer.
US08987122B2 Method of manufacturing semiconductor device
A method of manufacturing a semiconductor device, includes a wafer grinding step of, by means of a revolving grinding stone, forming a thinned portion in a wafer while at the same time forming a slope surrounding said thinned portion, wherein during said formation of said slope, said grinding stone is positioned so that there is always a space between said slope and the facing side of said grinding stone, wherein said thinned portion is thinner than a peripheral portion of said wafer, and wherein said slope extends along and defines an inner circumferential side of said peripheral portion and forms an angle of 75° or more but less than 90° with respect to a main surface of said wafer. The method of manufacturing a semiconductor device further includes a step of forming a semiconductor device in said thinned portion.
US08987117B2 Semiconductor optical integrated device and method for fabricating the same
A semiconductor optical integrated device includes a first semiconductor optical device formed over a (001) plane of a substrate and a second semiconductor optical device which is formed over the (001) plane of the substrate in a (110) orientation from the first semiconductor optical device and which is optically connected to the first semiconductor optical device. The first semiconductor optical device includes a first core layer and a first clad layer which is formed over the first core layer and which has a crystal surface on a side on a second semiconductor optical device side that forms an angle θ greater than or equal to 55 degrees and less than or equal to 90 degrees with the (001) plane.
US08987116B2 Production of electronic switching devices
A technique of producing one or more electronic switching devices, each switching device comprising a semiconductor channel between two electrodes, and a dielectric element separating said semiconductor channel from a switching electrode, the method comprising: depositing onto a substrate a layer of material for at least partly forming said semiconductor channel or said dielectric element of said one or more switching devices by transferring said material onto said substrate from a rotating first roller.
US08987109B2 Method for manufacturing bonded wafer and bonded SOI wafer
A method for manufacturing a bonded wafer includes: an ion implantation step of using a batch type ion implanter; a bonding step of bonding an ion implanted surface of a bond wafer to a surface of a base wafer directly or through an insulator film; and a delamination step of delaminating the bond wafer at an ion implanted layer, thereby manufacturing a bonded wafer having a thin film on the base wafer, wherein the ion implantation into the bond wafer carried out at the ion implantation step is divided into a plurality of processes, the bond wafer is rotated on its own axis a predetermined rotation angle after each ion implantation, and the next ion implantation is carried out at an arrangement position obtained by the rotation.
US08987108B2 Methods of forming semiconductor structures including bodies of semiconductor material
Semiconductor structures that include bodies of a semiconductor material spaced apart from an underlying substrate. The bodies may be physically separated from the substrate by at least one of a dielectric material, an open volume and a conductive material. The bodies may be electrically coupled by one or more conductive structures, which may be used as an interconnect structure to electrically couple components of memory devices. By providing isolation between the bodies, the semiconductor structure provides the properties of a conventional SOI substrate (e.g., high speed, low power, increased device density and isolation) while substantially reducing fabrication acts and costs associated with such SOI substrates. Additionally, the semiconductor structures of the present disclosure provide reduced parasitic coupling and current leakage due to the isolation of the bodies by the intervening dielectric material.
US08987106B2 Semiconductor device manufacturing method
A semiconductor device manufacturing method includes forming a channel dope layer having a first electric conductive-type inside of a semiconductor substrate, the channel dope layer being formed in a region except for a drain impurity region where dopant impurities for forming a low-concentration drain region are introduced, and the channel dope layer being separated from the drain impurity region; forming a gate electrode on the semiconductor substrate via a gate insulating film; and forming a low-concentration source region inside of the semiconductor substrate on a first side of the gate electrode, and forming a low-concentration drain region in the drain impurity region of the semiconductor substrate on a second side of the gate electrode, by introducing second electric conductive dopant impurities inside of the semiconductor substrate with the gate electrode as a mask.
US08987101B2 Method of forming strained source and drain regions in a P-type finFET structure
A method of forming strained source and drain regions in a P-type FinFET structure is disclose. The method comprises depositing an isolation layer on the FinFET structure; applying a lithography and etching process to expose the isolation layer in two areas on opposite sides of the gate over the source/drain region of the FinFET, and etching through the exposed isolation layer to expose the semiconductive material of the source/drain region in the two areas; forming a recess in each of the source/drain region from the exposed semiconductive material; selectively epitaxially growing another semiconductive material in the recesses to increase the source/drain strain; and removing the rest of the isolation layer.
US08987100B2 Method of fabricating fin-field effect transistors (finfets) having different fin widths
Provided are methods of forming field effect transistors. The method includes preparing a substrate with a first region and a second region, forming fin portions on the first and second regions, each of the fin portions protruding from the substrate and having a first width, forming a first mask pattern to expose the fin portions on the first region and cover the fin portions on the second region, and changing widths of the fin portions provided on the first region.
US08987094B2 FinFET integrated circuits and methods for their fabrication
A fin field effect transistor integrated circuit (FinFET IC) has a plurality of fins extending from a semiconductor substrate, where a trough is defined between adjacent fins. A second dielectric is positioned within the trough, and a protruding portion of the fins extends above the second dielectric. A first dielectric is positioned between the fin sidewalls and the second dielectric.
US08987093B2 Multigate finFETs with epitaxially-grown merged source/drains
Method of forming multi-gate finFETs with epitaxially-grown merged source/drains. Embodiments of the invention may include forming a plurality of semiconductor fins joined by a plurality of inter-fin semiconductor regions, depositing a sacrificial gate over a center portion of each of the plurality of fins, forming a first merge layer over a first end of each of the plurality of fins to form a first merged fin region, forming a second merge layer over the second end of each of the plurality of fins to form a second merged fin region, etching a portion of the first merged fin region to form a first source/drain base region, etching a portion of the second merged fin region to form a second source/drain base region, forming a first source/drain region on the first source/drain base region, and forming a second source/drain region on the second source/drain base region.
US08987091B2 III-N material structure for gate-recessed transistors
III-N transistors with recessed gates. An epitaxial stack includes a doped III-N source/drain layer and a III-N etch stop layer disposed between a the source/drain layer and a III-N channel layer. An etch process, e.g., utilizing photochemical oxidation, selectively etches the source/drain layer over the etch stop layer. A gate electrode is disposed over the etch stop layer to form a recessed-gate III-N HEMT. At least a portion of the etch stop layer may be oxidized with a gate electrode over the oxidized etch stop layer for a recessed gate III-N MOS-HEMT including a III-N oxide. A high-k dielectric may be formed over the oxidized etch stop layer with a gate electrode over the high-k dielectric to form a recessed gate III-N MOS-HEMT having a composite gate dielectric stack.
US08987090B2 Method of manufacturing a semiconductor device with device separation structures
A method of manufacturing a semiconductor device includes introducing at least a first and a second trench pattern including array trenches from a first surface into a semiconductor substrate, wherein an array isolation portion of the semiconductor substrate separates the first and second trench patterns. A buried gate electrode structure is provided in the first and second trench patterns at a distance to the first surface. In a single etch process, both a device separation trench having a first width is introduced into the array isolation portion and cell separation trenches having at most a second width that is smaller than the first width are introduced into semiconductor fins between the array trenches. Switching devices integrated in the same semiconductor die may be formed in a cost effective way.
US08987086B2 MIM capacitor with lower electrode extending through a conductive layer to an STI
The present disclosure provides a semiconductor device that includes a semiconductor substrate, an isolation structure formed in the semiconductor substrate, a conductive layer formed over the isolation structure, and a metal-insulator-metal (MIM) capacitor formed over the isolation structure. The MIM capacitor has a crown shape that includes a top electrode, a first bottom electrode, and a dielectric disposed between the top electrode and the first bottom electrode, the first bottom electrode extending at least to a top surface of the conductive layer.
US08987085B2 Methods for improving uniformity of cap layers
A method of forming an integrated circuit includes providing a semiconductor substrate, forming a metallization layer over the semiconductor substrate, wherein the metallization layer comprises a metal feature in a low-k dielectric layer and extending from a top surface of the low-k dielectric layer into the low-k dielectric layer, performing a treatment to the low-k dielectric layer to form a hydrophilic top surface, and plating a cap layer on the metal feature in a solution.
US08987075B2 Method for manufacturing a compound semiconductor device
A semiconductor device includes a substrate, a carrier transit layer disposed above the substrate, a compound semiconductor layer disposed on the carrier transit layer, a source electrode disposed on the compound semiconductor layer, a first groove disposed from the back of the substrate up to the inside of the carrier transit layer while penetrating the substrate, a drain electrode disposed in the inside of the first groove, a gate electrode located between the source electrode and the first groove and disposed on the compound semiconductor layer, and a second groove located diagonally under the source electrode and between the source electrode and the first groove and disposed from the back of the substrate up to the inside of the carrier transit layer while penetrating the substrate.
US08987073B2 Self-protected metal-oxide-semiconductor field-effect transistor
Device structures, design structures, and fabrication methods for a metal-oxide-semiconductor field-effect transistor. A gate structure is formed on a top surface of a substrate. First and second trenches are formed in the substrate adjacent to a sidewall of the gate structure. The second trench is formed laterally between the first trench and the first sidewall. First and second epitaxial layers are respectively formed in the first and second trenches. A contact is formed to the first epitaxial layer, which serves as a drain. The second epitaxial layer in the second trench is not contacted so that the second epitaxial layer serves as a ballasting resistor.
US08987072B2 Method of manufacturing an LTPS array substrate
The present disclosure discloses a method of manufacturing the LTPS array substrate, comprising: depositing a polysilicon layer and an amorphous silicon layer on the substrate successively and crystallizing the amorphous silicon layer to form the polysilicon layer by laser annealing; coating a photoresist layer covering the PMOS area, NMOS area and TFT area of the polysilicon layer; forming a polysilicon pattern and a channel by dry etching the polysilicon layer, then removing the regions of the photoresist layer which are thinner and covering the NMOS area and the TFT area by ashing, the region of the photoresist layer covering the PMOS area is remained. The present disclosure saves the cost of the equipment, improves the yield, reduces the design defect and the process difficulty of the conventional process using 8 photomasks.
US08987062B2 Active thermal control for stacked IC devices
Thermal conductivity in a stacked IC device can be improved by constructing one or more active temperature control devices within the stacked IC device. In one embodiment, the control devices are thermal electric (TE) devices, such as Peltier devices. The TE devices can then be selectively controlled to remove or add heat, as necessary, to maintain the stacked IC device within a defined temperature range. The active temperature control elements can be P-N junctions created in the stacked IC device and can serve to move the heat laterally and/or vertically, as desired.
US08987060B2 Method for making circuit board
A method for making the same is disclosed. First, a first substrate and a second substrate are provided. The first substrate includes a release film attached to a carrier. The second substrate includes a copper film covered with a solder mask. Second, the solder masked is patterned. Next, the release film and the patterned solder mask are pressed together so that the first substrate is attached to the second substrate. Then, the copper film is patterned to form a first pattern and a second pattern. The first pattern is in direct contact with the release film and the second pattern is in direct contact with the patterned solder mask. Later, a passivation is formed to cover the first pattern and the second pattern to form a circuit board structure. Afterwards, a package is formed on the carrier to form a packaging structure.
US08987058B2 Method for wafer separation
A plurality of macro and micro alignment marks may be formed on a wafer. The macro alignment marks may be formed in pairs at opposite edges of the wafer. The micro alignment marks may be formed to align to streets on the wafer along a first and second direction. A molding compound may be formed on the wafer. The macro alignment marks may be exposed from the molding compound. A pair of the micro alignment marks may be exposed from the molding compound at opposite ends of the streets along the first and the second direction. The wafer may be aligned to a dicing tool using pairs of the macro alignment marks. The dicing tool may be aligned to the streets using pairs of the micro alignment marks. The wafer may be diced using successive pairs of micro alignment marks along the first and second direction.
US08987057B2 Encapsulated wafer-level chip scale (WLSCP) pedestal packaging
Consistent with an example embodiment, there is semiconductor device assembled to resist mechanical damage. The semiconductor device comprises an active circuit defined on a top surface, contact areas providing electrical connection to the active circuit. There is a pedestal structure upon which the active circuit is mounted on an opposite bottom surface; the pedestal structure has an area smaller than the area of the active device. An encapsulation, consisting of a molding compound, surrounds the sides and the underside of the active device and it surrounds the contact areas. The encapsulation provides a resilient surface protecting the active device from mechanical damage. A feature of the embodiment is that the contact areas may have solder bumps defined thereon.
US08987054B2 Semiconductor devices and methods of making the same
In one embodiment, methods for making semiconductor devices are disclosed.
US08987053B2 Semiconductor package including flip chip controller at bottom of die stack
A semiconductor package including a plurality of stacked semiconductor die, and methods of forming the semiconductor package, are disclosed. In order to ease wirebonding requirements on the controller die, the controller die may be mounted directly to the substrate in a flip chip arrangement requiring no wire bonds or footprint outside of the controller die. Thereafter, a spacer layer may be affixed to the substrate around the controller die to provide a level surface on which to mount one or more flash memory die. The spacer layer may be provided in a variety of different configurations.
US08987052B2 Attachment of microelectronic components
Sub-micron precision alignment between two microelectronic components can be achieved by applying energy to incite an exothermic reaction in alternating thin film reactive layers between the two microelectronic components. Such a reaction rapidly distributes localized heat to melt a solder layer and form a joint without significant shifting of components.
US08987049B2 Gate insulator loss free etch-stop oxide thin film transistor
A method is provided for fabricating a thin-film transistor (TFT). The method includes forming a semiconductor layer over a gate insulator that covers a gate electrode, and depositing an insulator layer over the semiconductor layer, as well as etching the insulator layer to form a patterned etch-stop without losing the gate insulator. The method also includes forming a source electrode and a drain electrode over the semiconductor layer and the patterned etch-stop. The method further includes removing a portion of the semiconductor layer beyond the source electrode and the drain electrode such that a remaining portion of the semiconductor layer covers the gate insulator in a first overlapping area of the source electrode and the gate electrode and a second overlapping area of the drain electrode and gate electrode.
US08987046B2 Trap passivation in memory cell with metal oxide switching element
Non-volatile storage elements having a reversible resistivity-switching element and techniques for fabricating the same are disclosed herein. The reversible resistivity-switching element may be formed by depositing an oxygen diffusion resistant material (e.g., heavily doped Si, W, WN) over the top electrode. A trap passivation material (e.g., fluorine, nitrogen, hydrogen, deuterium) may be incorporated into one or more of the bottom electrode, a metal oxide region, or the top electrode of the reversible resistivity-switching element. One embodiment includes a reversible resistivity-switching element having a bi-layer capping layer between the metal oxide and the top electrode. Fabricating the device may include depositing (un-reacted) titanium and depositing titanium oxide in situ without air break. One embodiment includes incorporating titanium into the metal oxide of the reversible resistivity-switching element. The titanium might be implanted into the metal oxide while depositing the metal oxide, or after deposition of the metal oxide.
US08987043B2 Organic light emitting diode display and method for manufacturing organic light emitting diode display
A method of manufacturing an OLED display includes: forming an organic light emitting element on a first substrate; forming, on the organic light emitting element, a thin film encapsulation layer that seals the organic light emitting element with the first substrate; providing a second substrate; forming a flexible protection layer on the second substrate; attaching the first substrate and the second substrate to each other; and separating the second substrate from the flexible protection layer.
US08987040B2 Manufacturing means and process
A production device (2) and a method for forming multilayered (3, 4, 5, 6, 7) modules, in particular solar modules (1), which have at least one translucent sheet-like layer (3, 6) and at least one solar- or light-active element is provided. The production device (2) forms the layer structure and has an applicator (33) for a connecting layer (5, 7) for the aforementioned layers (3, 4, 6). Furthermore, the device has a controllable curve(arch)-forming device (17) for bending and rolling a sheet-like layer (3, 6) while the layers are being applied.
US08987038B2 Method for forming solar cell with selective emitters
A method for forming a solar cell with selective emitters is disclosed, including selectively removing a portion of a barrier layer on a substrate to form an opening, performing a texture etching process to the substrate to form a second texture structure in a second region under the opening of the barrier layer, wherein the substrate surface in the first region does not change from the first texture structure. The first texture structure and the second texture structure include a plurality of protruding portions and recessing portions. The distance between neighboring protruding portions of the first texture structure is L1, the distance between neighboring protruding portions of the second texture structure is L2, and L1 is 2˜20 times that of L2. The method for forming a solar cell with selective emitters further comprises removing the barrier layer and performing a doping process.
US08987037B2 Methods of manufacturing a solar cell
A method of manufacturing a solar cell includes forming a buffer layer between an optical absorption layer and a window electrode layer. Forming the buffer layer includes depositing a metal material on the optical absorption layer, supplying a non-metal material on the optical absorption layer, supplying a gas material including oxygen atoms on the optical absorption layer, and reacting the metal material with the non-metal material. The gas material reacts with the metal material and the non-metal material to form a metal sulfur oxide on the optical absorption layer.
US08987036B2 Solar battery module and solar battery array
A solar battery module (40) includes a stack of: a plurality of solar battery strings (30) and bus sections (32) connected to both ends of each of the plurality of solar battery strings (30); flexible resin layers (33a through 33c); and a flexible resin film (34). The flexible resin layers (33a through 33c) and the flexible resin film (34) have, on a light receiving surface side of solar battery cells (20), holes through which the bus sections (32) are each partially exposed. The exposed parts of the bus sections (32) serve as a respective plurality of electrically-connecting means (32a). A solar battery array (41) includes a plurality of solar battery modules (40). The plurality of solar battery modules (40) are electrically connected with each other via the plurality of electrically-connecting means (32a). This makes it possible to achieve a large-scale solar battery array (41) with high mechanical strength.
US08987034B2 Backside illumination CMOS image sensor and method of manufacturing the same
A method of manufacturing a backside illumination image sensor includes forming an epitaxial layer on a silicon (Si) substrate, and forming an inter-metal dielectric (IMD) on the epitaxial layer. The method includes forming a trench in one side region of the epitaxial layer, forming an insulating layer at a side wall and bottom of the trench, forming a color filter and microlens on the IMD, bonding a support wafer onto the IMD with the color filter and microlens formed therein, and/or removing the Si substrate.
US08987033B2 Method for forming CMOS image sensors
A method includes forming a blocking layer over a substrate, and etching the blocking layer to form a trench in the blocking layer. A dielectric layer is formed, wherein the dielectric layer comprises a first portion over the blocking layer, and a second portion in the trench. After the step of forming the dielectric layer, an implantation is performed to implant an impurity into the substrate to form a deep well region. After the implantation, the dielectric layer and the blocking layer are removed.
US08987032B2 Method for selective under-etching of porous silicon
A method for making a solar cell is disclosed. In accordance with the method of the present invention a composite wafer is formed. The composite layer includes a single crystal silicon wafer, a silicon-based device layer and sacrificial porous silicon sandwiched therebetween. The composite wafer is treated to an aqueous etchant maintained below ambient temperatures to selectively etch the sacrificial porous silicon and release or undercut the silicon-based layer from the single crystal silicon wafer. The released silicon device layer is attached to a substrate to make a solar cell and the released single crystal silicon wafer is reused to make additional silicon device layer.
US08987029B2 Protective thin films for use during fabrication of semiconductors, MEMS, and microstructures
A method of protecting a substrate during fabrication of semiconductor, MEMS devices. The method includes application of a protective thin film which typically has a thickness ranging from 3 angstroms to about 1,000 angstroms, wherein precursor materials used to deposit the protective thin film are organic-based precursors which include at least one fluorine-comprising functional group at one end of a carbon back bone and at least one functional bonding group at the opposite end of a carbon backbone, and wherein the carbon backbone ranges in length from 4 carbons through about 12 carbons. In many applications at least a portion of the protective thin film is removed during fabrication of the devices.
US08987028B2 Lattice-mismatched semiconductor structures with reduced dislocation defect densities and related methods for device fabrication
Fabrication of monolithic lattice-mismatched semiconductor heterostructures with limited area regions having upper portions substantially exhausted of threading dislocations, as well as fabrication of semiconductor devices based on such lattice-mismatched heterostructures.
US08987027B2 Two doping regions in lightly doped drain for thin film transistors and associated doping processes
A method is provided for fabricating thin-film transistors (TFTs) for an LCD having an array of pixels. The method includes depositing a first photoresist layer over a portion of a TFT stack that includes a conductive gate layer, and a semiconductor layer. The method also includes doping the exposed semiconductor layer with a first doping dose. The method further includes etching a portion of the conductive gate layer to expose a portion of the semiconductor layer, and doping the exposed portion of the semiconductor layer with a second doping dose. The method also includes depositing a second photoresist layer over a first portion of the doped semiconductor layer in an active area of the pixels to expose a second portion of the doped semiconductor layer in an area surrounding the active area, and doping the second portion of the doped semiconductor layer with a third doping dose.
US08987026B2 Semiconductor light emitting device
According to one embodiment, a semiconductor light emitting device includes an n-type layer, a light emitting layer, a p-type layer, and a transparent electrode. The n-type layer includes a nitride semiconductor and has a thickness not more than 500 nm. The light emitting layer is provided on the n-type layer. The p-type layer is provided on the light emitting layer and includes a nitride semiconductor. The transparent electrode contacts the n-type layer. The n-type layer is disposed between the transparent electrode and the light emitting layer.
US08987023B2 Light emitting device and manufacturing method thereof
A light emitting device includes: a substrate; a light emitting element disposed on the substrate; a wavelength conversion unit disposed on the substrate to cover at least an upper surface of the light emitting element; and a reflection unit formed to cover a side surface and a lower surface of the substrate and having a resin and a reflective filler dispersed in the resin. Light emitting devices having uniform characteristics can be obtained by minimizing a chromaticity distribution of white light with respect to the different light emitting devices.
US08987020B2 Semiconductor light-emitting device and method for manufacturing same
A method for manufacturing a semiconductor light-emitting device includes forming a multilayer body including a first semiconductor layer having a first major surface and a second major surface which is an opposite side from the first major surface, a second semiconductor layer including a light-emitting layer laminated on the second major surface of the first semiconductor layer, and electrodes formed on the second major surface of the first semiconductor layer and on a surface of the second semiconductor layer on an opposite side from the first semiconductor layer. The method includes forming a groove through the first semiconductor layer. The method includes forming a phosphor layer on the first major surface and on a side surface of the first semiconductor layer in the groove.
US08987019B2 Method of manufacturing an opto-electric device
A method of manufacturing an opto-electric device is disclosed, comprising the steps of providing a substrate (10), overlying a first main side of the substrate with an electrically interconnected open shunting structure (20), embedding the electrically interconnected open shunting structure in a transparent layer (30), removing the substrate from the embedded electrically interconnected open shunting structure, depositing a functional layer structure (40) over a free surface (31) formed after removal of the substrate.
US08987018B2 Method for forming a light-emitting case and related light-emitting module
A method for manufacturing a light-emitting case includes forming a flat panel light emitting diode, and covering the flat panel light emitting diode with transparent plastic material. The transparent plastic material has properties of flexibility, high gas-resistance and water-resistance. When the light-emitting case is forced, the shape of the light-emitting case can be changed.
US08987017B2 Light-emitting device
This disclosure discloses a method of manufacturing a light-emitting device, comprising proving a single growth substrate having a first major surface and a second major surface; forming a plurality of light-emitting stacks on the first major surface, wherein the light-emitting stacks are electrically connected to each other in series via a first electrical connecting structure; forming an electronic device on the second major surface; and forming a second electrical connecting structure extending from the first major surface to the second major surface and electrically connecting the first light-emitting stacks and the electronic device, wherein the electronic device comprises a resistance, an inductance, capacitance, or a rectifying device, and wherein the material of the resistance comprises tantalum nitride (TaN), silicon-chromium alloy (SiCr), or nickel-chromium alloy (NiCr).
US08987015B2 Method for fabricating semiconductor device
A method for fabricating a semiconductor device includes performing thermal cleaning for a surface of a silicon substrate in an atmosphere including hydrogen under a condition that a thermal cleaning temperature is higher than or equal to 700° C. and is lower than or equal to 1060° C., and a thermal cleaning time is longer than or equal to 5 minutes and is shorter than or equal to 15 minutes; forming a first AlN layer on the substrate with a first V/III source ratio, the forming of the first AlN layer including supplying an Al source to the surface of the substrate without supplying a N source, and supplying both the Al source and the N source; forming a second AlN layer on the first AlN layer with a second V/III source ratio that is greater than the first ratio; and forming a GaN-based semiconductor layer on the second AlN layer.
US08987014B2 Semiconductor wafer and method of forming sacrificial bump pad for wafer probing during wafer sort test
A semiconductor wafer contains a plurality of semiconductor die. A plurality of interconnect bump pads is formed over the semiconductor die. A plurality of sacrificial bump pads is formed in proximity to and diagonally offset with respect to the interconnect bump pads. The sacrificial bump pads have a different diameter than the interconnect bump pads. A conductive link is formed between each interconnect bump pad and proximate sacrificial bump pad. The sacrificial bump pads, interconnect bump pads, and conductive link are formed concurrently or during bump formation. The wafer is electrically tested by contacting the sacrificial bump pads. The electrical test identifies known good die and defective die. The sacrificial bump pads and a portion of the conductive link are removed after wafer probing. Bumps are formed over the interconnect bump pads. The semiconductor wafer can be sold or transferred to a third party after wafer probing without bumps.
US08987012B2 Method of testing a semiconductor package
A method of testing a semiconductor package is provided, including: disposing at least an interposer on a top surface of an adhesive layer, the interposer having a first surface and a second surface opposite to the first surface, a plurality of conductive elements disposed between the second surface of the interposer and the adhesive layer; disposing at least a semiconductor chip on the first surface of the interposer, and performing an electrical test on the semiconductor chip via the conductive elements, wherein if there are a plurality of semiconductor chips that are disposed on the first surface of the interposer, the step of disposing the semiconductor chip and performing the electrical test on the semiconductor chip is iterated; and removing the adhesive layer. By using the method, the fabrication cost and equipment cost of the semiconductor package are reduced, and product yield is increased.
US08987011B2 Method for determining the structure of a transistor
A method for determining the structure of a transistor having at least one first layer including GaN, one second layer including AlxGa1-xN disposed on the first layer, and one fourth layer including a metal or an alloy disposed on the second layer. The method includes setting the layer thickness of the second layer, setting the aluminum content x of the second layer, producing at least the second layer and the first layer, determining the surface potential of formula (I) and/or the charge carrier density n, and/or the charge carrier motility μ after producing the second layer and the first layer, and selecting the material of the fourth layer as a function of the at least one measurement result.
US08987010B1 Microprocessor image correction and method for the detection of potential defects
Systems and methods are provided for developing usable chip images in order to detect and screen defects or anomalies in a manufacturing environment. More specifically, a method is provided for manufacturing at least one wafer or chip. The method includes obtaining image data of the at least one wafer or chip. The method further includes correcting the image data to remove normal variation within the image data. The method further includes comparing the corrected image data to image data for at least one other wafer or chip to determine whether the corrected image data for the at least one wafer or chip shows a defect or anomaly beyond that of the normal variation. The method further includes placing the at least one wafer or chip into a category of fabrication based on the comparison.
US08987006B2 Method and system for providing a magnetic junction having an engineered barrier layer
A magnetic junction usable in a magnetic memory and a method for providing the magnetic memory are described. The method includes providing a pinned layer, providing an engineered nonmagnetic tunneling barrier layer, and providing a free layer. The pinned layer and the free layer each include at least one ferromagnetic layer. The engineered nonmagnetic tunneling barrier layer has a tuned resistance area product. In some aspects, the step of providing the engineered nonmagnetic tunneling barrier layer further includes radio-frequency depositing a first oxide layer, depositing a metal layer, and oxidizing the metal layer to provide a second oxide.
US08987005B2 Reagent for measuring agglutination and method of measuring agglutination
[PROBLEMS] To provide a reagent for measuring agglutination by using a reaction accelerator, which causes no spontaneous agglutination of receptor-sensitized carrier particles in the coexistence of these carrier particles, and a measurement method.[MEANS FOR SOLVING PROBLEMS] A reagent for measuring agglutination by using a specific amine compound, whereby aggregation based on a specific reaction can be accelerated without causing spontaneous agglutination of carrier particles, and measurement method.
US08986995B2 Methods of deriving differentiated cells from stem cells
The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
US08986994B2 Substituted pyridines and pyrimidines
Provided are compounds of formula (I) and/or salts thereof, of the class of substituted pyridines and pyrimidines, useful for inducing cardiomyogenesis, a process for producing cardiomyocyte-like cells from mammalian cells by culturing mammalian cells in the presence of the compound of formula (I), the pharmaceutical use of compounds of formula (I) for producing cardiomyocyte-like cells from omnipotent, pluripotent, or lineage committed mammalian cells, and the use of thus produced cardiomyocyte-like cells for treating disorders associated with impaired function of the heart.
US08986992B2 Expansion of stem/progenitor cells by inhibition of enzymatic reactions catalyzed by the Sir2 family of enzymes
Provided are ex vivo and in vivo methods of expanding renewable stem cells using agents capable of down-regulating Sir2 protein activity and/or expression, expanded populations of renewable stem cells, and uses thereof.
US08986988B2 Cell rolling separation
The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
US08986986B2 Cell lysis device and methods of lysing cells or viruses
A method of lysing at least one of a cell and a virus, the method including: contacting a sample, which includes at least one of a cell and a virus, with a plurality of beads which are disposed in a first chamber to obtain a combination of the sample and the beads; and agitating the combination of the sample and the beads to lyse the at least one of the cell and the virus, wherein in the first chamber a liquid volume fraction is 0.6 or less, and wherein the liquid volume fraction is a value obtained by dividing a liquid volume of the first chamber by a pure void volume equivalent to a sum of the liquid volume of the first chamber and a void volume of the first chamber.
US08986984B2 Method of propagating cells
A method of collecting embryonic-like stem cells from a placenta which has been treated to remove residual cord blood by perfusing the drained placenta with an anticoagulant solution to flush out residual cells, collecting the residual cells and perfusion liquid from the drained placenta, and separating the embryonic-like cells from the residual cells and perfusion liquid. Exogenous cells can be propagated in the placental bioreactor and bioactive molecules collected therefrom.
US08986982B2 Apparatus and method for a continuous rapid thermal cycle system
A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
US08986981B2 Detection of methylated DNA
The use of ion sensitive field effect transistor (ISFET) to detect methylated nucleotides in a DNA sample is described. A method of detecting methylated nucleotides in a DNA sample may include the steps of treating a sample of DNA with a reagent which discriminates between methylated and non-methylated nucleotides to provide treated DNA, amplifying the treated DNA and optionally sequencing the amplified DNA. An ISFET is used to monitor the addition of one or more dNTPs in the strand extension reactions during the amplification and/or sequencing step. Suitable apparatus is also provided.
US08986975B2 Production of sulfur-free nanoparticles by yeast
A method of producing sulfur-free nanoparticles involves growing yeast in a growth medium containing a source of an element in a bio-reducible oxidation state (e.g. Se(Vl), and, precipitating nanoparticles containing the element in a lower oxidation state (e.g. Se(O)) than the oxidation state of the element in the source. The method advantageously can provide substantially spherical nanoparticles at high production efficiencies.
US08986970B2 Detergent compositions containing Bacillus agaradhaerens mannanase and methods of use thereof
The present compositions and methods relate to an endo-β-mannanase cloned from Bacillus agaradhaerens, polynucleotides encoding the endo-β-mannanase, and methods of use thereof. Formulations containing the endo-β-mannanase are highly suitable for use as detergents.
US08986967B2 Marking paper products
Methods of marking paper products and marked paper products are provided. Some methods include irradiating the paper product to alter the functionalization of the paper.
US08986966B2 Microfluidic device for cell separation and uses thereof
The invention features methods for separating cells from a sample (e.g., separating fetal red blood cells from maternal blood). The method begins with the introduction of a sample including cells into one or more microfluidic channels. In one embodiment, the device includes at least two processing steps. For example, a mixture of cells is introduced into a microfluidic channel that selectively allows the passage of a desired type of cell, and the population of cells enriched in the desired type is then introduced into a second microfluidic channel that allows the passage of the desired cell to produce a population of cells further enriched in the desired type. The selection of cells is based on a property of the cells in the mixture, for example, size, shape, deformability, surface characteristics (e.g., cell surface receptors or antigens and membrane permeability), or intracellular properties (e.g., expression of a particular enzyme).
US08986961B2 Fermentative production of acetone from renewable resources by means of novel metabolic pathway
The invention describes a process for preparing acetone starting from acetyl-coenzyme A comprising process steps A. enzymatic conversion of acetyl-CoA into acetoacetyl-CoA B. enzymatic conversion of acetoacetyl-CoA into acetoacetate and CoA and C. decarboxylation of acetoacetate to acetone and CO2, which is characterized in that the coenzyme A is not transferred in process step B to an acceptor molecule. In addition, process step B is surprisingly catalyzed by enzymes of the classes of acyl-CoA thioesterase, acyl-CoA synthetase or acyl-CoA thiokinase.A completely novel metabolic pathway is concerned, because the enzymatic hydrolysis of acetoacetyl-CoA without simultaneous transfer of CoA to a receptor molecule has never previously been described for any microbial enzyme.
US08986956B2 Method for producing human epidermal growth factor in large volume from yeast
The present invention relates to a method for producing hEGF (human epidermal growth factor) which has the same activity as the wild form, in high concentration and with a high degree of purity. More specifically, the invention relates to an hEGF expression vector comprising a nucleic acid sequence coding for the polypeptide of sequence number 14; a host cell in which the expression vector has been genetically transformed; and a method for producing hEGF, comprising a step in which the expression vector is created and is genetically transformed in yeast from which the KEX1 gene is lacking. Using the method of the present invention, it is possible to produce a large volume of human derived EGF which has the same size and activity as human derived EGF, and this EGF can be used in various ways such as in medicine and cosmetics.
US08986955B2 Method for increasing thermal stability and retaining activity of a protein
The present invention provides a method and a system for increasing thermal stability of a target protein comprising fusing a starch binding protein (SBP) with the target protein to form a SBP-tagged recombinant protein and combining the SBP-tagged recombinant protein with a SBP-binding matrix. The present invention also provides a method for retaining an activity of a target protein in aquatic environment comprising fusing a starch binding protein (SBP) with the target protein to form a SBP-tagged recombinant protein and combining the SBP-tagged recombinant protein with a SBP-binding matrix.
US08986952B2 Anti-human NGF antibody
[Task] To provide an anti-human NGF antibody or an antigen-binding fragment thereof that is excellent in safety by reducing the risk of side effects such as effects on a fetus and thrombus formation while maintaining high neutralizing activity, and to provide means for preventing or treating various diseases in which human NGF is involved in the formation of pathological conditions, by using the antibody or the antibody-binding fragment thereof.[Means for Resolution] An anti-human NGF antibody Fab′ fragment comprising a heavy-chain variable region consisting of an amino acid sequence shown by SEQ ID NO:6 and a light-chain variable region consisting of an amino acid sequence shown by SEQ ID NO:4.
US08986950B2 Method of producing a low molecular weight organic compound in a cell
A method of producing a low molecular weight organic compound (e.g. a plant or bacteria secondary metabolite) in increased yields involving use of a microorganism cell, which comprises a gene involved in the biosynthesis pathway leading to a low molecular weight organic aglycon compound and a glycosyltransferase gene capable of glycosylating the produced aglycon.
US08986937B2 Compositions and methods for detecting autoantibodies
The invention provides compositions and methods for detecting thyroid hormone blocking immunoglobulin (TBI). The invention's methods are sensitive and specific for TBI, and may be used for the dual detection of both TBI and TSI. The invention's compositions and methods are useful for the diagnosis of diseases that are associated with the presence of TBI and/or TSI, for monitoring the progress of disease and/or treatment regimens, therapeutics, vaccines, etc., and for assisting clinicians in making treatment decisions.
US08986936B2 Post-translation modified cardiac troponin T as a biomarker of a risk for heart failure
The present invention relates to methods and kits for the prediction of risk for heart failure using post-translation modified forms of cardiac troponin T as a biomarker.
US08986925B2 Method for in vitro detection and/or quantification and/or identification of infectious compounds in a biological material
Method for in vitro detection and/or quantification and/or identification of infectious compounds present in a fluid medium M constituting a biological material, in which method a suspension of microbeads of solid polymer material capable of binding proteins is prepared; the microbeads are loaded with β2GPI proteins by coupling with a sufficient amount of β2GPI proteins; said microbeads are brought into contact with the fluid medium M while adding ions of at least one oxidizing metal, so as to bind the infectious compounds to the β2GPI proteins; the microbeads thus prepared are separated from their suspension medium, so as to obtain a residue; and the infectious compounds of the residue are detected and/or quantified and/or identified.
US08986924B2 Method of sequestering metals using thiosulfate polymers
A thiosulfate polymer composition includes an electron-accepting photosensitizer component, either as a separate compound or as an attachment to the thiosulfate polymer. The thiosulfate polymer composition can be applied to various articles, or used to form a predetermined polymeric pattern after photothermal reaction to form crosslinked disulfide bonds, removing non-crosslinked polymer, and reaction with a disulfide-reactive material. Such thiosulfate polymer compositions can also be used to sequestering metals.
US08986923B2 Aqueous base-developable negative-tone films based on functionalized norbornene polymers
Embodiments in accordance with the present invention encompass negative-tone, aqueous base developable, self-imagable polymer compositions useful for forming films that can be patterned to create structures for microelectronic devices, microelectronic packaging, microelectromechanical systems, optoelectronic devices and displays.
US08986921B2 Lithographic material stack including a metal-compound hard mask
A lithographic material stack including a metal-compound hard mask layer is provided. The lithographic material stack includes a lower organic planarizing layer (OPL), a dielectric hard mask layer, and the metal-compound hard mask layer, an upper OPL, an optional anti-reflective coating (ARC) layer, and a photoresist layer. The metal-compound hard mask layer does not attenuate optical signals from lithographic alignment marks in underlying material layers, and can facilitate alignment between different levels in semiconductor manufacturing.
US08986919B2 Resist composition, method of forming resist pattern and polymeric compound
A resist composition including a base component (A) which generates acid upon exposure and exhibits changed solubility in a developing solution under action of acid, the base component (A) including a resin component (A1) containing a structural unit (a0-1) having a group represented by general formula (a0-1) shown below and a structural unit (a1) derived from an acrylate ester which may have the hydrogen atom bonded to the carbon atom on the α-position substituted with a substituent and contains an acid decomposable group which exhibits increased polarity by the action of acid.
US08986915B2 Toner, method for producing the same, cartridge storing the same, process cartridge, and image forming apparatus
According to one embodiment, a toner includes at least one encapsulated particle containing a color developable compound, color developer and a color eraser and polymeric particles. The at least one encapsulated particle and the polymeric particles being aggregated and fused in dispersion liquid.
US08986913B2 Method and apparatus for inspecting a mask substrate for defects, method of manufacturing a photomask, and method of manufacturing a semiconductor device
According to one embodiment, a method of inspecting a mask substrate for defects, includes acquiring a defocus image of a partial region of a mask substrate using a dark-field optical system, acquiring a just-focus image of the partial region using the dark-field optical system, generating a set composed of first signals obtained from the defocus image and having signal intensities equal to or higher than a first threshold value, excluding, from the set, the first signals pertaining to parts in which signal intensities of signals obtained from the just-focus image are equal to or higher than a second threshold value, determining an inspection threshold value for signal intensities, on the basis of the first signals not excluded from, and remaining in, the sea.
US08986911B2 Multiple-patterning photolithographic mask and method
A composite mask suitable for multiple-patterning lithographic processes and a multiple-patterning photolithographic process utilizing the mask are disclosed. An exemplary embodiment includes receiving a mask having a plurality of sub-reticles and a substrate having one or more regions. A first sub-reticle of the plurality of sub-reticles is aligned with a first region of the one or more regions. A movement pattern is designated relative to the substrate. A first photolithographic process is performed including exposing the substrate using the mask to form a first exposed area on the substrate. An alignment of the mask relative to the substrate is shifted according to a first direction determined by the movement pattern. A second photolithographic process is performed including exposing the substrate using the mask to form a second exposed area on the substrate such that the second exposed area overlaps the first.
US08986905B2 Fuel cell interconnect
A fuel cell interconnect includes a first side containing a first plurality of channels and a second side containing a second plurality of channels. The first and second sides are disposed on opposite sides of the interconnect. The first plurality of channels are configured to provide a serpentine fuel flow field while the second plurality of channels are configured to provide an approximately straight air flow field.
US08986902B2 Fuel cell constituent part and manufacturing method thereof
A pair of gaskets is integrally formed with seal lips corresponding to each other and extending in the longitudinal direction of the gasket, and side portions disposed on either sides or one side of the seal lip and having a height lower than that of the seal lip. The plate-shaped attachment member includes a through-hole provided at a position where the side portions of the pair of gaskets communicate with each other so as to be formed therethrough in the thickness direction, and the pair of gaskets is integrally formed through the through-hole. An opening shape of the through-hole is set to be an elongated shape in the longitudinal direction of the gasket so as to make a width dimension of each of the side portions as small as possible.
US08986897B2 Fuel cell comprising single layer bipolar plates, water damming layers and MEA of diffusion layers locally treated with water transferring materials, and integrating functions of gas humidification, membrane hydration, water removal and cell cooling
A fuel cell constructed with single layer bipolar plates, water damming layers and membrane electrode assembly with gas diffusion layers locally impregnated with water transporting materials, which has reactant gas flow fields placed on both sides of the single layer plates, while cooling liquid flow fields are integrated at least on one side of the plates. Disclosed novel configuration of the fuel cell provides a united means for humidifying reactant gases, hydrating membrane, removing generated water and cooling cells.
US08986892B2 Separator including porous coating layer, method for manufacturing the separator and electrochemical device including the separator
A separator includes a non-woven fabric substrate having pores, fine thermoplastic powder located inside the pores of the non-woven fabric substrate, and a porous coating layer disposed on at least one surface of the non-woven fabric substrate. The fine thermoplastic powder has an average diameter smaller than that of the pores and a melting point lower than the melting or decomposition point of the non-woven fabric substrate. The porous coating layer includes a mixture of inorganic particles and a binder polymer whose melting point is higher than the melting or decomposition point of the fine thermoplastic powder. In the porous coating layer, the inorganic particles are fixedly connected to each other by the binder polymer and the pores are formed by interstitial volumes between the inorganic particles. Previous filling of the large pores of the non-woven fabric substrate with the fine thermoplastic powder makes the porous coating layer uniform.
US08986889B2 Positive active material for lithium secondary battery and method of manufacturing same
A positive active material for a lithium secondary battery comprises a core comprising a compound that can reversibly intercalate and deintercalate lithium; and a compound attached to the surface of the core and represented by Chemical Formula 1: Li1+xM(I)xM(II)2−xSiyP3−yO12,  [Chemical Formula 1] wherein M(I) and M(II) are selected from the group consisting of Al, Zr, Hf, Ti, Ge, Sn, Cr, Nb, Ga, Fe, Sc, In, Y, La, Lu, and Mg, and 0
US08986883B2 Negative electrode for lithium secondary battery and method for producing same
A negative electrode for a lithium secondary battery, in which α-Fe2O3 that is low in cost, has little environmental impact and has high theoretical capacity is used as an active material, maintains high adhesiveness between a current collector and an electrode layer, and can simultaneously achieve both of an improvement in the cycle characteristics and high capacity. In a negative electrode for a lithium secondary battery, which is configured of a current collector, and an electrode layer that is formed on the current collector and contains at least a negative electrode active material, a conductive assistant and a binder component, the negative electrode active material is composed of α-Fe2O3 particles that generate a conversion electrode reaction, the binder component is a mixture of polyamide acid and partially imidized polyamide acid. The electrode layer is configured so that a concentration of the binder component decreases as distanced from the current collector.
US08986879B2 Pouch type rechargeable battery
A pouch type rechargeable battery that comprises an electrode assembly comprising a first electrode, a second electrode, and a separator interposed between the first and second electrodes is disclosed. The battery further comprises a pouch case comprising a case cover and a case body that is formed with a space for receiving the electrode assembly therein and a sealing part that is formed around the space. The sealing part comprises side sealing sections where the width of each side sealing section is less than the depth of the space.
US08986877B2 Battery having flat terminals
A battery (100) provided by the invention includes an electrode assembly (30) having a current collector forming a positive electrode and a current collector forming a negative electrode; and a flat terminal (10a, 10b) joined to each current collector. The flat terminal (10a, 10b) has a flat portion (12) including a joint area (11) joined to the corresponding the current collector, and the flat terminal has a first curved portion (14) that is formed away from the joint area along the longitudinal direction (13) of the flat terminal.
US08986876B2 Cap assembly and secondary battery having the same
Provided are a cap assembly for a secondary battery. The cap assembly includes a cap-up, a PTC thermistor disposed under the cap-up, a vent disposed under the PTC thermistor, and an insulating plate disposed between the vent and the cap-up and preventing contact between the vent and the PTC thermistor. Here, the vent includes a curling part bent to cover an external surface of the insulating plate. Further, the secondary battery includes an electrode assembly, a can accommodating the electrode assembly and having an opening, and the cap assembly which seals the can.
US08986873B2 Battery pack
A battery pack includes at least two or more bare cells, a lead tab and an insulating member. Each of the bare cells has a first terminal portion. The lead tab is provided to the first terminal portion of the bare cell. The insulating member is interposed between the bare cell and the lead tab and is provided with an opening so that the bare cell and the lead tab are electrically connected to each other. In the battery pack, the insulating member includes two or more bare cell facing portions respectively corresponding to the bare cells, an extending portion that connects neighboring bare cell facing portions to each other, and guide portions respectively provided to the bare cell facing portions so as not to be arranged in one straight line.
US08986870B2 Power storage device
The present invention relates to a power storage device including: a positive electrode having a positive-electrode current collector, a positive-electrode active material with a plurality of first projections on the positive-electrode current collector, and a first insulator on an end of each of the plurality of first projections; a negative electrode having a negative-electrode current collector, a negative-electrode active material with a plurality of second projections on a surface of the negative-electrode current collector, and a second insulator on an end of each of the plurality of second projections; a separator between the positive electrode and the negative electrode; and an electrolyte provided in a space between the positive electrode and the negative electrode and containing carrier ions. In each of the first projections and the second projections, a ratio of the height to the width is 3 or more and 1000 or less to 1, i.e. (3 to 1000):1.
US08986869B2 Secondary battery and method of preparing the same
A shaft core includes a positive electrode shaft core portion having a positive electrode splaying portion at one end, a negative electrode shaft core portion having a negative electrode splaying portion at the other end, and an insulation portion that mutually insulates and integrates the positive and negative electrode shaft core portions. The positive electrode plate is electrically connected to the positive electrode collector in a state of being splayed through the positive electrode splaying portion, and the negative electrode plate is electrically connected to the negative electrode collector being splayed through the negative electrode splaying portion. The positive and negative electrode shaft core splaying portions press and open their respective electrode laminates at the end surfaces of the wound electrode group, the positive electrode connection piece and the positive electrode collecting portion are welded, and the negative electrode connection piece and the negative electrode collecting portion are also welded.
US08986864B2 Battery with housing and degassing system
A battery housing for a hybrid vehicle battery includes a degassing system on a floor of the housing. The degassing system includes a base body configured for attachment to the floor, where the base body includes an opening in an upper section and is at least partially permeable to a liquid in a lower section. The degassing system also includes a guide in the base body and a float provided in the base body. The guide is configured to guide the float.
US08986859B2 Magnetic disk substrate, magnetic disk, and magnetic disk device
It is an object to provide a magnetic disk substrate highly reliable to prevent the occurrence of crash failure even if a magnetic disk is rotated at high speed, and suitable for a hard disk that starts and stops by the load/unload method, and a magnetic disk using such a substrate. The representative structure of a magnetic disk substrate is a disk-shaped glass substrate 10 having a generally flat main surface 11, an end face 12, a chamfered face 13 formed between the main surface 11 and the end face 12, and an offset portion, at the periphery of the main surface 11, raised or lowered with respect to a flat surface, other than the periphery, of the main surface 11, and characterized in that the magnitude of the offset portion is approximately uniform over the entire circumference of the glass substrate 10.
US08986856B2 Iridium complex and organic light-emitting element including the same
The present invention provides a novel iridium complex and an organic light-emitting element including the same. The novel iridium complex includes phenylpyrazole as a ligand and has a basic skeleton in which a pyrimidine ring is bonded to a phenyl ring.
US08986855B2 Heterocyclic compound and organic light-emitting device including the same
Derivatives of benzo[h]naphtho[1,2-f]quinoline and organic light emitting devices (OLEDs) including them are disclosed. The subject compounds impart high efficiency, low driving voltage, high luminance and long lifespan to the OLEDs. The subject compounds may be used as light emitting materials, as electron transporting materials, or as electron injecting materials. Because the subject compounds have high glass transition temperatures or high melting points, OLEDs including them exhibit high durability in storage or operation. Suitable substituents may be selected from deuterium, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, aryloxy, arylthio, aryl, aryl- or heteroaryl-substituted amino, heteroaryl, condensed polycyclic, halogen, cyano, nitro, hydroxyl and carboxyl groups.
US08986854B2 Composite material, material for light-emitting element, light-emitting element, light-emitting device and electronic device
The present invention provides a composite material for a light-emitting element including a high molecular compound having an arylamine skeleton and an inorganic compound showing an electron accepting property to the high molecular compound. The absorption spectrum of the composite material is different from absorption spectra of the high molecular compound and the inorganic compound which each form the composite material. In other words, a composite material having an absorption peak in a wavelength which is seen in the absorption spectra of neither the high molecular compound nor the inorganic compound forming the composite material is superior in carrier transporting and injecting properties and a favorable material. In addition, the composite material can be formed by a wet method such as a sol-gel method, it can be apply to the increase of substrate size easily in a manufacturing process and advantageous industrially.
US08986853B2 Red phosphorescent composition and organic electroluminescent device using the same
A red phosphorescent compound includes a host material being capable of transporting an electron or a hole; and a dopant material represented by following Formula 1: and each of R1 to R4 is one of the group consisting of hydrogen atom (H), C1 to C6 substituted or non-substituted alkyl group, C1 to C6 substituted or non-substituted alkoxy group, and halogen atom.
US08986849B2 Hot stamped high strength part excellent in post painting anticorrosion property and method of production of same
A hot stamped high strength part which is excellent in post painting anticorrosion property, which hot stamped high strength part has an alloy plating layer including an Al—Fe intermetallic compound phase on the surface of the steel sheet. The alloy plating layer is comprised from phases of a plurality of intermetallic compounds, a mean linear intercept length of crystal grains of a phase containing Al: 40 to 65 mass % among the phases of the plurality of intermetallic compounds is 3 to 20 μm, an average value of thickness of the Al—Fe alloy plating layer is 10 to 50 μm, and a ratio of the average value of thickness to the standard deviation of thickness of the Al—Fe alloy plating layer satisfies the following relationship: 0
US08986845B2 Ceramic composite article having laminar ceramic matrix
A ceramic composite article includes ceramic carbide fibers and a ceramic matrix in which the ceramic carbide fibers are embedded. The ceramic matrix includes a laminar structure with at least one layer of a first ceramic material and at least one layer of a second, different ceramic material.
US08986842B2 Color conversion films comprising polymer-substituted organic fluorescent dyes
The present invention concerns a color conversion film comprising at least one active layer, said layer comprising an organic fluorescent dye containing a fluorescent core, wherein said dye is substituted with at least one polymer segment. It also concerns its method of preparation.
US08986841B2 Reinforced glass-ceramic article and enamel suitable for the coating thereof
A process for reinforcing a glass-ceramic article, into which a maximum tension is introduced beneath the surface of the glass-ceramic, advantageously in proximity to said surface. The invention also relates to an enamel that can be used for this reinforcement, this enamel being formed from a glass frit having the following composition, the proportions being expressed as weight percentages: SiO250-66% MgO3-8% Na2O 7-15% K2O0-3% Li2O 0-12% CaO 0-10% BaO 0-15% Al2O30-3% ZrO20-3% ZnO0-5% B2O30-8% the sum of the alkaline-earth metal oxides CaO+BaO moreover being between 8 and 15%, and the sum of the alkali metal oxides Na2O+K2O+Li2O moreover being between 7 and 20%. The reinforced glass-ceramics obtained by the process.
US08986836B2 Microspheres and their methods of preparation
Carbon microspheres are doped with boron to enhance the electrical and physical properties of the microspheres. The boron-doped carbon microspheres are formed by a CVD process in which a catalyst, carbon source and boron source are evaporated, heated and deposited onto an inert substrate.
US08986834B2 Polyester imide resin insulating coating material, insulated wire using same, and coil
A insulated wire includes a conductor, and an insulating coating on a periphery of the conductor. The insulating coating includes an insulating film formed by applying and baking a polyester imide resin insulating coating material, and the insulating film has a relative permittivity of less than 3.5 both in a dried state and in a moisture-absorbed state. The insulating film is formed by applying and baking a polyester imide resin insulating coating material including an imide dicarboxylic acid and an alcohol component, the imide dicarboxylic acid being obtained by synthesizing a diamine component including aromatic diamine having not less than three aromatic rings and an acid component including aromatic tricarboxylic acid anhydride.
US08986831B2 Pressure sensitive adhesive tear tape
A tape that includes a cellulosic substrate defining a first surface and an opposing second surface; a pressure sensitive adhesive disposed on the first surface of the cellulosic substrate; and an encapsulated fibrous material disposed on the first surface of the cellulosic substrate or the second surface of the cellulosic substrate.
US08986827B2 Barrier coating composition with organic particles
A moisture vapor and oxygen transmission resistant flexible film has a polymeric base layer and a barrier layer of discrete particles of a first organic polymer dispersed throughout a matrix of a second organic polymer. Preferably, the first and second polymers are water insoluble and water soluble, respectively. The barrier layer is formed by depositing onto the base layer a coating composition of finely divided insoluble organic polymer particles suspended in an aqueous solution of the water soluble organic polymer, a crosslinking agent and surfactant. The coating composition is heated to crosslink the barrier layer polymers and evaporate solvent to provide a barrier film suitable for packaging applications. Optionally, the film can be metalized to increase barrier properties.
US08986820B2 Thermoformed articles from sheet incorporating cycloolefin copolymer
Thermoformed articles include cycloolefin/ethylene copolymer and LLDPE. The articles are formed with an areal draw ratio of 1.5 and greater and exhibit unexpectedly elevated stiffness along with ductility suitable for forming deep-draw parts. Multilayer sheet is used for achieving a desired set of properties.
US08986815B2 Flame retardant polymer jacket
A jacket configured to encase building component insulation is provided. The jacket comprises at least inner layer, an intermediate layer attached to the inner layer, and an outer layer attached to the intermediate layer. The inner layer, intermediate layer and outer layers are configured for attachment to each other with the use at least one of heat, polymeric material, and pressure. Additionally, the jacket complies with the standards of flame retardancy as provided by ASTM C1136.
US08986814B2 Superhydrophobic surfaces
Surfaces having a hierarchical structure—having features of both microscale and nanoscale dimensions—can exhibit superhydrophobic properties and advantageous condensation and heat transfer properties. The hierarchical surfaces can be fabricated using biological nanostructures, such as viruses as a self-assembled nanoscale template.
US08986809B2 Methods and apparatus for digital composites
In exemplary implementations of this invention, a digital material comprising many discrete units is used to fabricate a sparse structure. The units are reversibly joined by elastic connections. Each unit comprises fiber-reinforced composite material. Each unit is small compared to the sparse structure as a whole. Likewise, in a sparse structure made from this digital material, the number of types of units is small compared to the total number of units. The digital material is anisotropic. This anisotropy may be due to different fiber orientations within each unit. Furthermore, different units in a single sparse structure may be oriented in different directions and in different, non-parallel planes. In some cases, the digital material is reinforced with carbon fibers, and connections between units are stronger than the units themselves. The small discrete units may be assembled into a strong, lightweight sparse structure, such as an airframe.
US08986805B2 Vacuum insulation panel, refrigerator with vacuum insulation panel and manufacturing method for vacuum insulation panel
A vacuum insulation panel includes a core material having a bending groove at at least one surface thereof, and an envelope material to cover an outer surface of the core material and an inner surface of the bending groove. Also, a refrigerator with the vacuum insulation panel and a manufacturing method for the vacuum insulation panel are provided.
US08986804B2 Method for producing structural member and structural member
A narrow prepreg sheet 20N is bonded along a ridge C, and wide prepreg sheet 20W is bonded to other portions, whereby the wide prepreg sheet 20W having no cut line is bonded to both side portions of the ridge C.In a portion in which a spar 10 is curved, the narrow prepreg sheet 20N is bonded in an axial direction of the spar 10 while divided into plural pieces, and a length of the narrow prepreg sheet 20N is adjusted according to a radius of curvature of the curved portion in the axial direction of the spar 10, whereby various radii of curvature are easily dealt with.
US08986800B2 Cooking bag and use of the cooking bag for cooking food
Cooking bag containing a copolymer containing monomer units of a dimerised fatty acid or a derivative thereof. Use the cooking bag for cooking food. A process for storing and cooking of food comprising the steps: a) filling the cooking with food, b) storing the filled cooking bag at a temperature below 0° C., c) cooking the food.
US08986798B2 Material for attenuating impact energy
A new and novel impact energy attenuation material, impact energy attenuation module employing the material and a fit system for optimizing the performance thereof is provided. Non-linear energy attenuating material consisting of a plurality of loose particles is employed for impact energy dissipation. The loose particles are preferably spherical elastomeric balls. An impact energy attenuation module includes a container that holds the loose particles. The impact energy attenuation module can be provided in a wide range of sizes and shapes and the loose particles can be provided in different materials, sizes, density, compaction and hardness to suit with the application at hand. A matrix of impact energy attenuation module are provided about the surface of a shell to provide the required impact energy attenuation. The material, impact energy attenuation module and system of the present invention are well suited for protection of body parts and other cushioning and protection needs.
US08986791B2 Low gloss aqueous coating compositions containing poly(ethylene oxide) for use on leather
The present invention relates to aqueous coating compositions having low gloss for treating natural or synthetic leather. These aqueous coating compositions contain one or more water soluble poly(ethylene oxide) resins having the general formula [—CH2CH2O—]n and one or more polymer binders.
US08986785B2 Method and apparatus for continuous sulfonization of discrete article
An apparatus for continuous sulfonization of discrete articles comprising a feeder box for drying the discrete articles with ultra-dry air, a sulfonization chamber for treating the discrete articles with sulfur trioxide gas, a conveyor assembly for transporting the discrete articles from the feeder box to the sulfonization chamber, and a neutralizing tank for treating the discrete articles with neutralizing fluid. The sulfonization chamber includes a rotating dial plate with a circular periphery and an upper surface extending radially from and rotatable about a center axis (A) for receiving the discrete articles at the circular periphery. A plurality of arcuate guides extend perpendicularly from a guide arm toward the rotating dial plate and are spaced radially outward from one another along a radial (R) extending radially from the center axis (A) for moving the discrete articles radially inward in a spiral path during rotation of the rotating dial plate.
US08986784B2 Fine droplet atomization for liquid precursor vaporization
A method for forming a droplet aerosol for vaporization and subsequent thin film deposition on a substrate. The method includes drawing a gas from a compressed gas source and drawing a liquid from a liquid source. The liquid and gas are conjoined in either a coaxial flow relationship or a radial flow relationship or an angular relationship between radial and coaxial flow wherein the gas engages the liquid to form droplets suitable for vaporization and subsequent thin film deposition on a substrate.
US08986777B2 Vapor sheath for liquid dispensing nozzle
The present disclosure provides a device for preventing the fouling of a liquid dispensing nozzle. The end of the dispensing nozzle is placed in a hollow interior of a band carrying the same solvents that are dispensed by the nozzle. The solvent on the band evaporates into a gap between the ring and dispensing nozzle, thus providing a vapor sheath or environment that helps to prevent the fouling of the dispensing nozzle.
US08986776B2 Method for producing an antimicrobial coating on a technical surface
The invention relates to a method for producing a microbial substance-releasing layer on a technical surface. The inventive method comprises three steps: a) producing a solution from polyvinylacetate, a preservative agent and a solvent, b) applying the solution to the technical surface, and c) drying the solution applied to the technical surface while forming the layer. The inventive method is characterized by using benzoic acid, sorbic acid, natamycin, bacteriocines, plant extracts or mixtures thereof as the preservative agent and an ethanol/water mixture, ethyl acetate or acetone as the solvent.
US08986774B2 Supercritical fluid extruded food product
An expanded food product made using supercritical fluid extrusion is disclosed. The food product comprises particular characteristics that demonstrate a light, porous, crispy texture has been obtained.
US08986770B2 Process for fabricating leaf tea products
Shown is a process for manufacturing a fabricated leaf tea product. The process includes the steps of: (i) providing a concentrated liquid tea composition; (ii) providing a base leaf tea; (iii) combining the concentrated liquid tea composition with the base leaf tea to form a tea mixture having a total soluble solids content of at least 50% by dry weight of the mixture; and (iv) drying the tea mixture. At least 20% by weight of the base leaf tea has a particle size of +16 mesh and/or the tea mixture is sorted according to particle size to yield a fraction wherein at least 20% by weight of the fraction has a particle size of +16 mesh; and the time between forming the tea mixture (step iii) and drying (step iv) is at least 5 minutes.
US08986769B2 Methods for preserving endogenous TGF-β
The present invention is directed to a processing method and a selection of ingredients that will retain TGF-β levels, bioactivity, and/or bioavailability in a liquid nutritional product. The method involves selecting one or more protein ingredients that have been subjected to a heat load comprising medium-heat or less; combining the protein ingredients with other components of the liquid nutritional product to form a slurry; subjecting the slurry to a pressure of from about 2500 psi to about 3500 psi at a temperature of from about 55° C. to about 65° C. for about 5 to 20 seconds; subjecting the slurry to a temperature of about 135 to 150° C. for about 1.5 to 15 seconds; and cooling the slurry to a temperature of less than about 8° C. over about 30 minutes or less.
US08986767B2 Additive manufacturing system and method with interchangeable cartridges for printing customized chocolate confections
An additive manufacturing system for printing a chocolate confection, the system comprising a platen, a print head, and a cartridge configured to be removably secured to the print head, wherein the cartridge contains a supply of the chocolate material.
US08986757B2 Essential oils inhibit mold on wood
Methods of treating wood lumber to inhibit growth of mold fungi by surface treating the wood lumber with an essential oil, diluted or undiluted, being geranium Egyptian, thyme, dill weed or rosemary. Various surface treatments include dipping, spraying, brushing and vapor exposure.
US08986756B2 Composition comprising the extract of combined herbs for preventing and treating liver disease
The present invention is related to a combined herb composition comprising herbs of Coriolus versicolor, Astragalus membranaceus Bunge, and additionally comprising at least one herb selected from group consisting of Schisandra chinensis, and Artemisia capillaris, according to the need for the prevention and treatment of liver disease and methods of using the above crude drug composition and pharmaceutical composition as hepato-protective agent.
US08986755B1 Skin moisturizer
An organic skin moisturizer, which extends and improves the skin cells life cycle, comprised of Sea Buckthorn seed oil, Camellia seed oil, Argan seed oil, Pomegranate seed oil, Meadowfoam seed oil, d-alpha tocopherol, Lecithin oil, Rosemary essential oil, Tea Tree oil, Helichrysum oil, and Coffee Arabica oil. The oils are blended together resulting in a compound that is easily applied to the skin for superior results to keep the skin cells healthier longer. This compound was created to address the Hayflick limit, which is that all skin cells can only divide a specific number of times before the skin cell dies.
US08986753B2 Weight loss compositions and methods for appetite suppression
A beverage composition for weight loss is provided which includes cayenne pepper; a palate enhancing agent selected from the group consisting of fruits, herbs, vegetables and mixtures thereof, the agent including pulp of the fruits, the herbs, the vegetables or the mixtures thereof; a least two spices selected from the group consisting of black or white pepper, ginger, cinnamon, mustard seed and mixtures thereof; and water in an amount from 80 to 99% by weight of the composition; and wherein the composition has a total calorie content from 0 to 100 based on 100 gram of the composition.
US08986751B2 Medicinal orobancheace extracts
Pharmaceutical extracts from Egyptian broomrape have proven efficacy against HCV and NAFLD. Compositions and method of making and using same are provided.
US08986747B2 Thrush treatment paste
A composition for treating hoof thrush and similar ailments in horses is composed of a blend of copper sulfate and chlorhexidine dispersed in a viscous carrier. Preferably, the copper sulfate makes up 20 to 45 percent by weight of the final product and the chlorhexidine compound accounts for 1 to 5 percent by weight. A viscous carrier constitutes the balance of the formulation.
US08986744B2 Stem cell populations and methods of use
The present invention relates to populations of stem cells, methods for isolating these stem cell populations, and methods repairing, regenerating, and reconstituting tissues using the these stem cell populations. The invention additionally relates to methods of screening agents that promote growth, engraftment, or differentiation of stem cells.
US08986743B2 Animal model for the human immune system, and method for producing the same
In a method for preparing an animal model for the human immune system in a non-human mammal, human stem cells with hematopoietic potential are transplanted into a non-human mammal. The non-human mammal is conditioned with cell culture supernatant of a culture of human cell lines, cells and/or tissue. The cell culture supernatant is derived from cell lines producing cytokines and other molecular mediators.
US08986736B2 Method for delivering particulate drugs to tissues
The present invention is concerned with delivering a pharmaceutical composition to a tissue target of a mammalian subject for treating brain diseases or disorders. The process includes the steps of: (i) providing a dispersion of the pharmaceutical composition as particles having an average particle size of from about 150 nm to about 100 microns, and (ii) administering the dispersion to the mammalian subject for delivery to the tissue target of a portion of the pharmaceutical composition by cells capable of reaching the tissue target. The dispersion of the pharmaceutical composition as particles, for example, can be phagocytized or adsorbed by the cells prior or subsequent to administration into the mammalian subject. The dispersion of the pharmaceutical composition can be administered to the central nervous system or the vascular system. After administration, the loaded cells transport the pharmaceutical composition as particles into the tissue target.
US08986735B2 Solid dosage form containing a taste masked active agent
A solid dosage form containing a taste masked active agent is provided. The solid dosage form may be provided as a water soluble film that is disintegrable in the oral cavity to deliver and release the taste masked active agent. The disintegrable film includes at least one water soluble polymer and a taste masked ketoprofen active. Also provided are methods for preparing the solid dosage form and for using the solid dosage to administer an effective dosage of an active agent, such as ketoprofen, into the oral cavity for absorption.
US08986734B2 Material with bacteriostatic properties
The invention relates to a method for making a composite material including a porous polymer matrix containing HEMA monomers and in which silver nanoparticles are dispersed, and to the use thereof as an anti-microbial material.
US08986730B2 Methods for sealing a vascular puncture
Methods for sealing a puncture communicating with a blood vessel are provided that include introducing a porous carrier formed from lyophilized hydrogel or other material into the puncture. The plug may include at least first and second hydrogel precursors and a pH adjusting agent carried by the porous carrier in an unreactive state prior to exposure to an aqueous physiological environment. Once exposed to bodily fluids, the carrier expands as the lyophilized material hydrates to enhance and facilitate rapid hemostasis of the puncture. When the plug is placed into the puncture, the natural wetting of the plug by bodily fluids (e.g., blood) causes the first and second precursors to react and cross-link into an adhesive or “sticky” hydrogel that aids in retaining the plug in place within the puncture.
US08986729B2 Palatable suspending vehicle for pharmaceutical ingredients
The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages. The polysaccharide can be a starch, modified starch, or glycogen. The aqueous medium and individual components of the vehicle provide a palatable and easily ingested drug preparation. The invention also provides a vehicle containing an aqueous medium, suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages, buffer, and artificial sweetener, the combined suspending vehicle having a pH of about 3 to about 10 and an osmolality of 300 mOmsol or less.
US08986725B2 Silicone-peroxide compositions for long-term, controlled oxygen release
A composite for delivering extended-release of oxygen is disclosed. The composite can include a biocompatible polymeric support having a plurality of solid peroxide particles suspended therein. The polymer support can exhibit an oxygen tension value of at least 40 mmHg for a period of 14 days. The weight ratio of biocompatible polymeric support to solid peroxide particles can range from 1:1 to 99:1. Also disclosed is a method of using the composite to deliver oxygen to cells in both in vivo and in vitro environments.
US08986722B2 Pest control composition
It is an object of the present invention to provide a pest control composition capable of exerting a high effect on pests such as spider mites and aphids even at low concentration using a food/food additive with high safety to the human body and the environment. The present inventors have intensively studied to solve the above problem and found that, among polyglycerol fatty acid esters widely used as a food additive, a composition containing a polyglycerol fatty acid ester which has an HLB of 5 or less and is liquid at ordinary temperature and also a nonionic surfactant has a high effect on pests even at low concentration, and that the possibility for pests to develop resistance to the composition is extremely low, and the present invention has been completed.
US08986721B2 Personal care implement containing a stable reactive skin care and cleansing composition
Skin care or cleansing implements are described containing a liquid, semisolid or solid cleansing or skin treatment composition that is releasably associated with the implement. The composition is substantially nonaqueous and has a continuous and a discontinuous phase. Components of the discontinuous phase can react with each other or with water when water is blended with the nonaqueous cleansing or skin treatment composition during consumer use. Methods for treating the skin with the inventive implements are also described.
US08986712B2 Peptides derived from HIV-1 gp41 transmembrane domain for t-immunomodulation
The present invention relates to peptides, derivatives and analogs comprising an amino acid sequence derived from the transmembrane domain of HIV gp41 protein, pharmaceutical compositions comprising same, and uses thereof for therapy of inflammatory diseases and disorders, such as T-cell and/or monocyte mediated diseases.
US08986711B2 Vaccine to protect animals against leishmania
The present invention is generally related to the prevention of leishmaniasis in animals, particularly infection caused by Leishmania sp., based on the use of Leishmania infantum P36 protein or an immunogenic fragment of the latter, or involving an expression system for the mentioned protein or fragment—optionally in combination with a compound stimulating the production of a Th1-type cellular immune response—and comprising various vaccination protocols in application to Leishmania sp. based on the mentioned vaccine.
US08986710B2 Neisseria meningitidis compositions and methods thereof
In one aspect, the invention relates to an isolated polypeptide comprising an amino acid sequence that is at least 95% identical to SEQ ID NO: 71. In another aspect, the invention relates to an immunogenic composition including an isolated non-lipidated, non-pyruvylated ORF2086 polypeptide from Neisseria meningitidis serogroup B, and at least one conjugated capsular saccharide from a meningococcal serogroup.
US08986707B2 gM-negative EHV-mutants without heterologous elements
The present invention relates to the field of animal health and in particular of Equine Herpes Viruses (EHV) wherein the gene encoding the protein gM is absent, and which is free of heterologous elements. Further aspects of the invention relate to pharmaceutical compositions comprising said viruses, uses thereof, and methods for the prophylaxis and treatment of EHV infections. The invention also relates to pharmaceutical compositions comprising the combination of EHV-1 and EHV-4 viruses wherein the gene encoding the protein gM is absent and which is free of heterologous elements.
US08986706B2 Newcastle disease virus vectored herpesvirus vaccines
The present invention encompasses recombinant Newcastle Disease Virus-Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.
US08986704B2 Mutant fragments of OspA and methods and uses relating thereto
The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
US08986701B2 Enzyme prodrug cancer therapy selectively targeted to tumor vasculature and methods of production and use thereof
Methods of treating cancer by targeting tumor vasculature using an enzyme prodrug cancer therapy treatment are provided.
US08986697B2 Antibodies for the treatment of Clostridium difficile-associated infection and disease
Provided herein are reagents, compositions, and therapies with which to treat Clostridium difficile infection and related disease conditions and pathologies, such as Clostridium difficile-associated diarrhea, resulting from infection by Clostridium difficile bacteria and the enterotoxins produced by these bacteria. In particular, antibodies or antigen-binding fragments thereof that bind specifically to toxin A and/or toxin B of C difficile and neutralize the activities of these toxins; compositions comprising such antibodies; and methods of using the antibodies and the compositions are provided.
US08986696B2 Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
The present invention relates to trans-capsularly administering into a diseased joint an inhibitor of p38 MAP kinase or a different therapeutic agent.
US08986694B1 Targeting human nav1.7 variants for treatment of pain
The invention relates to human targets of interest (TOI), anti-TOI ligands, kits compositions and method.
US08986692B2 Anti-VEGF monoclonal antibody and pharmaceutical composition comprising said antibody
The present invention provides an anti-VEGF monoclonal antibody, which has the variable region of heavy chain comprising the amino acid sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, and/or the variable region of light chain comprising the amino acid sequences of SEQ ID NO:4, SEQ ID NO:5 and SEQ ID NO:6. The antibody can be produced by the cell line with the preservation number of CGMCC NO. 3233. The invention also provides the use of said antibody for the manufacture of medicaments for the treatment of a disease that is relevant to VEGF, wherein further provided are pharmaceutical composition, agents, kits and chips comprising said antibody, as well as the cell line with the preservation number of CGMCC NO. 3233.
US08986690B2 Modulation of activity of neurotrophins
The present invention relates to methods for modulating the activity of one or more neurotrophins, such as neural growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4 (NT-4), in an animal and methods for treatment of a disease or disorder in an individual by modulation of neurotrophin activity. The modulation is carried out by interfering with binding between a neurotrophin and a receptor of the Vps10p-domain receptor family or modulating the expression of a receptor of the Vps10p-domain receptor family. Methods for screening for agents capable of modulating neurotrophin activity and agents selected using these screening methods are also disclosed, as are methods for determining the effect of an agent on one or more neurotrophins in cells. The present invention also pertains to methods for modulating the transport of one or more neurotrophins.
US08986689B2 Compositions and methods for brain delivery of analgesic peptides
The present invention relates to non-invasive brain delivery technology for centrally-acting analgesic peptides. Specifically, the invention is directed to compounds comprising an antibody or fragment thereof capable of transmigrating across the blood brain barrier (BBB) and an analgesic peptide. Compositions and methods of using the compounds or compositions are also provided.
US08986688B2 WAP domain fusion polypeptides and methods of use thereof
This invention relates to fusion proteins that include a whey acidic protein (WAP) domain-containing polypeptide and a second polypeptide. Additionally, the invention relates to fusion proteins that include a WAP domain-containing polypeptide, a second polypeptide, and a third polypeptide. The second and/or third polypeptides of the fusion proteins of the invention are an Fc polypeptide; an albumin polypeptide; a cytokine targeting polypeptide; or a serpin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.
US08986685B2 Compositions and methods for increasing bone mineralization
Described herein are pharmaceutical compositions comprising an anti-sclerostin antibody and an inhibitor of bone resorption.
US08986684B2 Methods and compositions for treating autoimmune disease
The disclosure relates to OX-2/CD200 (herein referred to as CD200) antibodies and methods of treating autoimmune disease.
US08986682B2 Method to increase the absorption of unsaturated fatty acids by human infants
The present invention relates to a method to increase the absorption by a human infant of at least one unsaturated fatty acid, said method comprising the enteral administration to said infant of recombinant human bile-salt-stimulated lipase (rhBSSL). In another aspect the invention also relates to a method to improve the visual and/or cognitive development of a human infant, said method comprising the enteral administration to said infant of rhBSSL. Such methods have particular utility for preterm human infants, particular those in medical need of increasing their absorption of or availability to such unsaturated fatty acids. In further aspects, the invention relates to kits, packaged-pharmaceutical-products, recombinant human bile-salt-stimulated lipase and pharmaceutical compositions, in each case useful for increasing the absorption by a human infant of at least one unsaturated fatty acid, or for increasing the visual and/or cognitive development of a human infant.
US08986681B2 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl-tRNA synthetases
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
US08986679B2 Somatic stem cells
A method of treating a cellular proliferative disorder in a subject by obtaining from a subject a bodily fluid sample containing a plurality of cells, incubating the sample with EDTA or heparin in a container until the sample is separated into an upper layer and a lower layer, collecting the upper layer, isolating from the upper layer a population of somatic stem cells that are 0.3-6.0 micrometers in size, differentiating the somatic stem cells to dendritic cells in a medium containing GCSF, SCF, EGF, PDGF, bFGF, and IL-3, purifying the dendritic cells, contacting the dendritic cells thus purified with a cancer antigen, and administrating an effective amount of the dendritic cells presenting the cancer antigen to a subject in need thereof.
US08986676B2 MNTF differentiation and growth of stem cells
The present invention provides methods for inducing differentiation of an embryonic stem cell into a motor neuron using a motoneuronotrophic factor (MNTF) or its peptide analogs. The present invention further provides a method for isolating a population of stem cell derived motor neurons and a population of cells comprising the differentiated neural cells. Additionally, the present invention is directed to a method of enhancing the survival of the differentiated neural cells in long term cell cultures. Finally, the present invention provides compositions containing MNTF or its peptide analogs for therapeutic use in conjunction with stem cells.
US08986671B2 Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof
The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for dermatological conditions, gastroesophageal reflux, vesico-ureteral reflux, urinary incontinence, fecal incontinence, heart failure, and myocardial infarction.
US08986670B2 IgG stimulated remyelination of peripheral nerves
The present invention is based on the discovery of polyclonal IgG's ability to promote Schwann cell maturation, differentiation, and myelin production. Methods for treating non-idiopathic, demyelinating peripheral neuropathies in mammals, where the neuropathy is not immune-mediated or infection-mediated, through the administration of polyclonal IgG are provided. Types of demyelinating peripheral neuropathies treatable with the present invention include peripheral nerve trauma and toxin-induced peripheral neuropathies. Alternatively, a composition of polyclonal IgGs can be applied directly to a peripheral nerve cell to induce maturation, differentiation into a myelinating state, and myelin expression or promote cell survival.
US08986669B2 Method for removing phosphate and polymer used therefore
Polymers and compositions utilizing such polymers are disclosed for treating hyperphosphatemia and other illnesses associated with elevated serum phosphate levels. Phosphate binding polymers, or a pharmaceutically acceptable salt of the polymers, comprise pendent groups extending from a backbone of the polymer. Each pendent group comprises at least two nitrogen-bearing functional groups which bind phosphate. Variations of such polymer and compositions are disclosed.
US08986667B2 Cosmetic composition with skin tightening effect
The present invention relates to a mixture, having a skin-tightening effect, which is made up of: 10 to 80% by weight of a polysaccharide, preferably of an alginate, having a molecular weight of less than 600,000 Daltons, preferably less than 400,000 Daltons and more preferably less than 200,000 Daltons, 15 to 75% by weight of a polyhydroxylated agent selected from sugars and their derivatives, particularly sugar esters and sugar, ethers, preferably sorbitol, 3 to 15% by weight of poly(vinyl alcohol) or polyvinylpyrrolidone, and 0 to 25% by weight of cellulose or of a derivative of cellulose, such as carboxymethylcellulose or hydroxymethylcellulose. The present invention also relates to cosmetic compositions which contain this mixture.These cosmetic compositions enable a mechanical smoothing of the surface of the skin to be obtained progressively with great comfort of use and enables a good fixing of make-up products.
US08986666B2 Treatment of animal litter with ferric sulfate granules
Methods of treating animal litter and/or bedding material for control of volatile ammonia and soluble phosphorous include applying granular partially hydrated ferric sulfate to the litter. The partially hydrated ferric sulfate ranges from gray to tan in color and is spread onto the litter at a rate effective to reduce ammonia volatilization and reduce soluble phosphorous. Relative to reagent grade ferric sulfate, the partially hydrated ferric sulfate exhibits lower hygroscopicity and higher deliquescence. The ferric sulfate is prepared by a process comprising oxidizing ferrous sulfate with sulfuric acid using a molecular oxygen oxidizing agent at an elevated pressure relative to atmospheric and at a temperature of 60° C. to 140° C. to produce a gray to tan colored granular product.
US08986662B2 Use of silane and siloxane bis(biphenyl) triazine derivatives as UV absorbers
Disclosed is the use of silane and siloxane bis(biphenyl)triazine derivatives of formula (1), wherein n is a number from 1 to 4; if n=1, X is *-L-Sil; or a radical of formula (11′), L is a linker selected from a radical of formula (2); R1, R2, R3 independently from each other are C1-C22alkyl; C6-C20aryl; C1-C22alkoxy; or O—C6-C20aryl; R4, R5, R6 and R7 independently from each other are hydrogen; C1-C22alkyl; C6-C20aryl; C1-C22alkoxy; or O—C6-C20aryl; b is a number from 0 to 30; c is a number from 0 to 6; and d is a number from 0 to 1; p is a number from 1 to 250; q is a number from 0 to 250; and Sil, Sil1 and Sil2 independently from each other are a silane-, oligosiloxane or polysiloxane moiety; if n=2, X is a bivalent radical of formula (1a); or (1b); x is a number from 2 to 250; y is a number from 0 to 250; and z is a number from 1 to 50; if n=3, X is a trivalent radical containing a silane-, oligosiloxane or polysiloxane moiety; If n=4, X is a tetravalent radical of formula (1c); and A is a radical of formula (111′) as UV absorbers.
US08986660B2 Process for producing (3S)-1-menthyl 3-hydroxybutyrate and sensate composition
Disclosed is a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling, a sensate composition which comprises the same, and various products that comprise said sensate composition. Also disclosed is a cooling agent comprising (3S)-1-menthyl 3-hydroxybutyrate represented by the following formula (I)
US08986659B2 Diamond, precious and semi-precious dust polishing agent for dental veneers and teeth
A diamond dust polishing agent for home use and professional use in the care of natural tooth enamel and dental veneers comprised of a quantity of diamond dust coated with a lubricant in conjunction with a paste for carrying the lubricant coated diamond dust, or other semi-precious, non-toxic abrasive dust, said diamond dust being of a size of approximately 500 nanometers or less to a size of approximately 5 nanometers. The size of the dust of both the diamond and the semi-precious stone may vary, depending on the degree of abrasiveness and the lubricant employed. The diamond dust (and semi-precious dust) polishing agent permits the user to maintain the polish and luster of the natural tooth enamel and veneer at home without adversely abrading or damaging the surface thereof.
US08986656B2 Method for evaluating specific incorporation of D-glucose into cells
An object of the present invention is to provide a method for accurately evaluating the specific incorporation of D-glucose into cells. The present invention as a means for achieving the object is characterized by comprising contacting a D-glucose derivative that has a fluorescent chromophore in the molecule and is specifically incorporated into cells and an L-glucose derivative that has a fluorescent chromophore in the molecule with different cells in the same cell strain to be evaluated, respectively, comparing the fluorescence emitted by the D-glucose derivative that has a fluorescent chromophore in the molecule and is specifically incorporated into cells with the fluorescence emitted by the L-glucose derivative that has a fluorescent chromophore in the molecule, and evaluating the specific incorporation of D-glucose into cells relative to L-glucose by taking the difference between the two kinds of fluorescence intensities.
US08986654B2 Labelled and un-labelled methyl-pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
The present invention relates to certain labelled or un-labelled pyrrolyl-oxadizolyl-diazabicyclononane derivatives and their medical use. Furthermore, the present invention relates to the use of said derivatives in their labelled form in diagnostic methods, in particular for in vivo receptor imaging (neuroimaging).
US08986653B2 Labeled iodinated tropane formulation
A diagnostic formulation is provided comprising a tropane having a radioactive concentration of at least 1.6 mCi/mL at least about 51 hours post creation. The diagnostic formulation optionally comprises a radiolabeled dopamine transporter (DAT) ligand useful in the diagnosis of Parkinson's disease (PS). One example of a radiolabeled dopamine transporter (DAT) ligand example is [123I]-2β-carbomethoxy-3β-(4-flurophenyl)-N-(3-iodo-E-allyl)nortropane.
US08986644B2 Method for preparation of high purity, crystalline cobalt nitrate from spent cobalt/silica catalyst
A method for preparing crystalline cobalt nitrate. The method includes: 1) calcining a spent Co/SiO2 catalyst, cooling the calcined material to room temperature, and grinding it to yield a powder; 2) heating the powder in a fluidized bed reactor; 3) adding the heated powder into excess dilute nitric acid solution and filtering to obtain a cobalt nitrate solution; 4) adjusting the pH value of the cobalt nitrate solution to 1.5, adding a preheated oxalic acid solution, adjusting a pH value of the resulting solution to 1.5, immediately filtering the resulting solution to yield a precipitate of cobalt oxalate, washing the precipitate of cobalt oxalate to yield a neutral filtrate; 5) drying the precipitate and calcining to yield cobalt oxide; 6) dissolving the cobalt oxide in nitric acid to yield a second cobalt nitrate solution; and 7) evaporating the second cobalt nitrate solution to obtain crystalline cobalt nitrate.
US08986643B2 Silicide compositions containing alkali metals and methods of making the same
The invention relates to a method of making alkali metal silicide compositions, and the compositions resulting from the method, comprising mixing an alkali metal with silicon and heating the resulting mixture to a temperature below about 475° C. The resulting compositions do not react with dry O2. Also, the invention relates to sodium silicide compositions having a powder X-ray diffraction pattern comprising at least three peaks with 2Theta angles selected from about 18.2, 28.5, 29.5, 33.7, 41.2, 47.4, and 56.2 and a solid state 23Na MAS NMR spectra peak at about 18 ppm. Moreover, the invention relates to methods of removing a volatile or flammable substance in a controlled manner. Furthermore, the alkali metal silicide compositions of the invention react with water to produce hydrogen gas.
US08986642B2 Metal oxide or semimetal oxide spherical beads, a process for making, and a process for using
The present invention relates to spherical beads comprising at least one metal and/or semimetal oxide, having a mean diameter in the range from 10 to 120 μm, a BET surface area in the range from 400 to 800 m2/g and a pore volume in the range from 0.3 to 3.0 cm3/g, wherein the diameter of a given bead at any one point of said bead deviates by less than 10% from the average diameter of said bead and the surface of said bead is substantially smooth, and also to a process for producing these spherical beads, to a particulate catalyst comprising the spherical beads and to the use of the spherical beads as catalysts or catalyst carriers.
US08986641B1 Amphiphilic nanosheets and methods of making the same
In some embodiments, the present invention provides amphiphilic nanosheets that comprise lamellar crystals with at least two regions: a first hydrophilic region, and a second hydrophobic region. In some embodiments, the amphiphilic nanosheets of the present invention also comprise a plurality of functional groups that are appended to the lamellar crystals. In some embodiments, the functional groups are hydrophobic functional groups that are appended to the second region of the lamellar crystals. In some embodiments, the lamellar crystals comprise α-zirconium phosphates. Additional embodiments of the present invention pertain to methods of making the aforementioned amphiphilic nanosheets. Such methods generally comprise appending one or more functional groups to a stack of lamellar crystals; and exfoliating the stack of lamellar crystals for form the amphiphilic nanosheets.
US08986640B1 System and method for recovering ammonia from a chilled ammonia process
An ammonia recovery system and method for removing ammonia from a gas stream is provided. The system includes an ammonia recovery vessel for contacting a solution, having a dissolved acidic salt, with the gas stream, having ammonia. The dissolved acidic salt solution absorbs the ammonia in the gas stream to provide an ammonia-lean gas stream and an ammonia-rich solution. The ammonia-rich solution is heated within an ammonia stripper to release the ammonia from the ammonia-rich solution to thereby generate an ammonia-rich gas stream and the solution having dissolved acidic salt. A heat exchanger heats the dissolved acidic salt from the ammonia stripper prior to the solution being provided to the ammonia recovery system. The acidic salt has a low thermal decomposition.
US08986635B2 Exhaust system for a lean-burn IC engine comprising a PGM component and a SCR catalyst
Methods are disclosed for reducing or preventing a selective catalytic reduction (SCR) catalyst disposed on a first substrate monolith in an exhaust system of a lean-burn internal combustion engine from becoming poisoned with platinum group metal (PGM) which may volatilize from a catalyst composition comprising PGM disposed on at least one second substrate monolith upstream of the SCR catalyst. The methods comprise adsorbing volatilized PGM in at least one PGM trapping material, which is disposed on a third substrate monolith disposed between the first substrate monolith and the second substrate monolith.
US08986634B2 Method for recovering metals from waste aluminum catalyst
The present invention refers to a method being easy to recover metals including nickel and aluminum from waste aluminum catalysts, thereby entirely promoting the recovering rate. Said method comprises: preparing and roasting a waste aluminum catalyst with sodium salts, and then obtaining a first solution comprising vanadium and molybdenum, and a dreg comprising nickel and aluminum through leaching and filtrating; collecting and mixing the dreg with alkali powders to obtain a mixture of the dreg and alkali powders, roasting the mixture at 300 to 1000° C. with aluminum in the dreg reacting with hydroxyl generated from the roasting of mixture and further generating aluminum hydroxide, and then obtaining a second solution comprising aluminum and a concentrate having nickel through another leaching and filtrating; and recovering aluminum from the second solution and recovering nickel from the concentrate.
US08986631B2 Reactor vessel for performing a steam reforming reaction and a process to prepare synthesis gas
A reactor vessel for performing a steam reforming reaction having a vessel inlet for natural gas and steam; a vessel inlet for a hot gaseous medium; a vessel outlet for the steam reforming product; and a reactor space which is a bed of steam reforming catalyst, which reactor space inlet is fluidly connected to the inlet for natural gas and steam and at its outlet end fluidly connected with the outlet for the gaseous product; wherein inside the catalyst bed a passageway is provided fluidly connected to the vessel inlet for the hot gaseous medium for passage of hot gaseous mixture counter currently to the flow of reactants in the catalyst bed.
US08986629B2 Sensor circuit for controlling, detecting, and measuring a molecular complex
A device for controlling, detecting, and measuring a molecular complex is disclosed. The device comprises a common electrode. The device further comprises a plurality of measurement cells. Each measurement cell includes a cell electrode and an integrator electronically coupled to the cell electrode. The integrator measures the current flowing between the common electrode and the cell electrode. The device further comprises a plurality of analog-to-digital converters, wherein an integrator from the plurality of measurement cells is electrically coupled to one analog-to-digital converter of the plurality of analog-to-digital converters.
US08986628B2 Method and apparatus for fluid dispersion
A microfluidic method and device for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid is provided. The device can be fabricated simply from readily-available, inexpensive material using simple techniques.
US08986626B2 Probe arrangement for exchanging in a controllable way liquids with micro-sized samples of material like biological cells
The invention relates to a probe arrangement (10g) for exchanging in a controllable way liquids with micro-sized samples of material like biological cells, especially in connection with an scanning probe microscope, said probe arrangement (10g) comprising a probe holder (11) with at least one embedded first channel (18) and a cantilever (12) with at least one embedded second channel (15) and being provided to be attached to said probe holder (11) in a way that at least one aperture (19) of the first channel (18) is connected to at least one aperture (17) of the second channel (15) in a way that permits the liquid-tight transfer of a liquid between said first and second channels (15, 18). A safe and easy use of the probe arrangement is achieved by having the cantilever (12) permanently attached to said probe holder (11) to form a prefabricated probe unit (10g).
US08986625B2 Hydrogen sulphide sampling method
A method for sampling a sulphur-containing solid product including supplying a gas flow comprising hydrogen sulphide, bringing the gas flow into contact with a solid reagent and reacting the solid reagent with the hydrogen sulphide contained in the gas flow, the reaction fixing the sulphur of the hydrogen sulphide by forming a sulphur-containing solid product which is different in color from the solid reagent, and recovering the sulphur-containing solid product. The invention also relates to a device suitable for the implementation of this method.