Document Document Title
US08884334B2 Composite layer stacking for enhancement mode transistor
A transistor includes a first layer of a first type disposed over a buffer layer and having a first concentration of a first material. A first layer of a second type is disposed over the first layer of the first type, and a second layer of the first type is disposed over the first layer of the second type. The second layer of the first type having a second concentration of a first material that is greater than the first concentration of the first material. A source and a drain are spaced laterally from one another and are disposed over the buffer layer. A gate disposed over at least a portion of the second layer of the first type and disposed within a recessed area defined by the first and second layers of the first type and the first layer of the second type.
US08884332B2 Nitride semiconductor device
A nitride semiconductor device includes a semiconductor substrate and a nitride semiconductor layer disposed on the semiconductor substrate. The semiconductor substrate includes a normal region, a carrier supplying region, and an interface current blocking region. The interface current blocking region surrounds the normal region and the carrier supplying region. The interface current blocking region and the carrier supplying region include impurities. The carrier supplying region has a conductivity type allowing the carrier supplying region to serve as a source of carriers supplied to or a destination of carriers supplied from a carrier layer generated at an interface between the nitride semiconductor layer and the semiconductor substrate. The interface current blocking region has a conductivity type allowing the interface current blocking region to serve as a potential barrier to the carriers.
US08884330B2 LED wavelength-converting structure including a thin film structure
A wavelength-converting structure for a wavelength-converted light emitting diode (LED) assembly. The wavelength-converting structure includes a thin film structure having a non-uniform top surface. The non-uniform top surface is configured increase extraction of light from the top surface of a wavelength-converting structure.
US08884329B2 Semiconductor light-emitting element, electrode structure and light-emitting device
It is an object to improve joining properties of electrodes and reliability of the electrodes for supplying electrical power to a semiconductor. The semiconductor light-emitting element includes an n-type semiconductor layer, a light-emitting layer, a p-type semiconductor layer, a transparent conductive layer, a p-electrode formed on the transparent conductive layer and an n-electrode formed on the n-type semiconductor layer. The p-electrode includes a p-side second metal layer composed of a metallic material containing Au and provided to be exposed to the outside and a p-side first metal layer composed of a metallic material containing Au with hardness higher than that of the metallic material composing the p-side second metal layer, the p-side first metal layer being provided closer to the transparent conductive layer than the p-side second metal layer along the p-side second metal layer.
US08884328B2 Light emitting device, light emitting device package, and lighting system
Provided is a light emitting device. The light emitting device includes a light emitting structure layer comprising a first conductive type semiconductor layer, an active layer, and a second conductive type semiconductor layer, a first electrode connected to the first conductive type semiconductor layer, a current spreading layer on the second conductive type semiconductor layer, an insulation layer on the first electrode, and a second electrode comprising at least one bridge portion on the insulation layer and a first contact portion contacting at least one of the second conductive type semiconductor layer and the current spreading layer.
US08884324B2 Semiconductor light-emitting device
A semiconductor light-emitting device includes a substrate, an LED chip mounted on the substrate, and a resin package covering the LED chip. The substrate includes a base and a wiring pattern formed on the base. The resin package includes a lens. The base includes an upper surface, a lower surface and a side surface extending between the upper surface and the lower surface. The LED chip is mounted on the upper surface of the base. The side surface of the base is oriented in a lateral direction. The wiring pattern includes a pair of first mount portions and a pair of second mount portions. The paired first mount portions are formed on the lower surface of the base. The paired second mount portions are oriented in the lateral direction and offset from the side surface of the base in the lateral direction.
US08884321B2 Luminous element
A light emitting device according to the embodiment includes a first conductive semiconductor layer; an active layer over the first conductive semiconductor layer; a second conductive semiconductor layer over the active layer; a bonding layer over the second conductive semiconductor layer; a schottky diode layer over the bonding layer; an insulating layer for partially exposing the bonding layer, the schottky diode layer, and the first conductive semiconductor layer; a first electrode layer electrically connected to both of the first conductive semiconductor layer and the schottky diode layer; and a second electrode layer electrically connected to the bonding layer.
US08884317B2 Semiconductor light-emitting device
A semiconductor light-emitting device includes: a semiconductor chip having a nonpolar plane as a growth surface and configured to emit polarized light; and a reflector having a reflective surface. When a plane forming an angle of 45° relative to a direction of polarization of the polarized light is a plane L45, the reflective surface of the reflector reflects at least a part of light in the plane L45 in a normal line direction of the growth surface of the semiconductor light-emitting chip. The reflector includes a plurality of reflective surfaces, the plurality of reflective surfaces are arranged in a shape of a square in plan view, and when an angle between the direction of polarization of the polarized light and one side of the shape formed by the plurality of reflective surfaces is θ2, the angle θ2 is not less than 17° and not more than 73°.
US08884316B2 Non-common capping layer on an organic device
A first method comprises providing a plurality of organic light emitting devices (OLEDs) on a first substrate. Each of the OLEDs includes a transmissive top electrode. The plurality of OLEDs includes a first portion of OLEDs and a second portion of OLEDs that is different from the first portion. The first method further includes depositing a first capping layer over at least the first portion of the plurality of OLEDs such that the first capping layer is optically coupled to at least the first portion of the plurality of OLEDs. A second capping layer is deposited over at least the second portion of the plurality of OLEDs such that the second capping layer is optically coupled to the second portion of the plurality of OLEDs but not the first portion of the plurality of OLEDs.
US08884314B1 Circuitry configurable based on device orientation
The present disclosure is directed to circuitry configurable based on device orientation. Example circuitry may comprise at least one device location and configurable conductors. The at least one device location may include at least two conductive pads onto which a device may be populated by a manufacturing process. The configurable conductors may be coupled to each of the at least two conductive pads. The configurable conductors may be configured by adding conductive material to at least one configurable conductor or subtracting at least part of at least one configurable conductor. For example, conductive material may be added to close a space between two segments of a configurable conductor to form a conduction path. Alternatively, at least part of at least one of a plurality of configurable conductors coupled to a conductive pad may be subtracted (e.g., cut) to stop conduction in the at least one configurable conductor.
US08884312B2 Light emitting device and lighting apparatus including the same
A light emitting device is disclosed. The disclosed light emitting device includes a light emitting structure including a first-conductivity-type semiconductor layer, an active layer, and a second-conductivity-type semiconductor layer, a second electrode layer disposed beneath the light emitting structure and electrically connected to the second-conductivity-type semiconductor layer, a first electrode layer including a main electrode disposed beneath the second electrode layer, and at least one contact electrode branching from the main electrode and extending through the second electrode layer, the second-conductivity-type semiconductor layer and the active layer, to contact the first-conductivity-type semiconductor layer, and an insulating layer interposed between the first electrode layer and the second electrode layer and between the first electrode layer and the light emitting structure. The first-conductivity-type semiconductor layer includes a first region and a second region having a smaller height than the first region, and the first region overlaps with the contact electrode.
US08884311B2 Optoelectronic semiconductor chip and method for producing same
An optoelectronic semiconductor chip includes a semiconductor layer stack and a radiation exit face or radiation entrance face, wherein the semiconductor layer stack includes an active layer that generates or receives electromagnetic radiation, and a plurality of nanostructures arranged in the semiconductor layer stack and/or on the radiation exit or entrance face, at least some of the nanostructures including at least one substructure.
US08884310B2 Direct formation of graphene on semiconductor substrates
The invention generally related to a method for preparing a layer of graphene directly on the surface of a semiconductor substrate. The method includes forming a carbon-containing layer on a front surface of a semiconductor substrate and depositing a metal film on the carbon layer. A thermal cycle degrades the carbon-containing layer, which forms graphene directly upon the semiconductor substrate upon cooling. In some embodiments, the carbon source is a carbon-containing gas, and the thermal cycle causes diffusion of carbon atoms into the metal film, which, upon cooling, segregate and precipitate into a layer of graphene directly on the semiconductor substrate.
US08884297B2 Microcrystalline silicon film, manufacturing method thereof, semiconductor device, and manufacturing method thereof
A manufacturing method of a microcrystalline silicon film includes the steps of forming a first microcrystalline silicon film over an insulating film by a plasma CVD method under a first condition; and forming a second microcrystalline silicon film over the first microcrystalline silicon film under a second condition. As a source gas supplied to a treatment chamber, a deposition gas containing silicon and a gas containing hydrogen are used. In the first condition, a flow rate of hydrogen is set at a flow rate 50 to 1000 times inclusive that of the deposition gas, and the pressure inside the treatment chamber is set 67 to 1333 Pa inclusive. In the second condition, a flow rate of hydrogen is set at a flow rate 100 to 2000 times inclusive that of the deposition gas, and the pressure inside the treatment chamber is set 1333 to 13332 Pa inclusive.
US08884293B2 Display device, method of manufacturing the same, and electronic unit
A display device includes: a thin film transistor; and a wiring layer; the thin film transistor including a control electrode, a semiconductor layer facing the control electrode, a first electrode made of a light transmissive material and electrically connected to the semiconductor layer, and a second electrode including a metal film having resistance lower than that of the light transmissive material, the second electrode being electrically connected to each of the semiconductor layer and the wiring layer, wherein a difference in ionization tendency between a material configuring the metal film and a conductive material configuring a part or whole of the wiring layer is smaller than a difference in ionization tendency between the light transmissive material and the conductive material.
US08884292B2 Transflective TFT-LCD and method for manufacturing the same
Embodiments of the disclosed technology provide a transflective transistor thin film array substrate and a method for manufacturing the same. The transflective thin film transistor array substrate, comprising pixel units defined by gate lines and data lines, and each pixel unit comprises a thin film transistor and a common electrode and is divided into a reflective region and a transmissive region. The reflective region comprises a reflective electrode and a second pixel electrode of the reflective region, the transmissive region comprises first and second pixel electrodes of the transmissive region, and the second pixel electrode of the reflective region and the first and second pixel electrodes of the transmissive region are provided in one pixel electrode layer.
US08884286B2 Switching element, display substrate and method of manufacturing the same
A switching element includes an active pattern including a channel portion, a source portion connected to the channel portion, and a drain portion connected to the channel portion, the source portion, a gate electrode overlapping the channel portion of the active pattern, a gate insulation layer disposed between the channel portion of the active pattern and the gate electrode, a source electrode disposed on the source portion of the active pattern to make ohmic contact with the source portion, and a drain electrode disposed on the drain portion of the active pattern to make ohmic contact with the drain portion. The drain portion and the channel portion of the active pattern include the same or substantially the same material.
US08884281B2 Organic EL element
Provided is an organic EL element which withstands mass production of organic EL display panels, and promises driving at a low voltage and high luminous efficiency due to excellent hole-injection efficiency. Specifically, an organic EL element is formed by sequentially laminating an anode, a hole injection layer, a buffer layer, a light-emitting layer, and a cathode on one surface of a substrate. The hole injection layer is a at least 2 nm thick tungsten oxide layer formed under predetermined film forming conditions, and includes an occupied energy level that is 1.8 eV to 3.6 eV lower than a lowest energy level of a valence band of the hole injection layer in terms of a binding energy. This reduces the hole injection barrier between the anode and the hole injection layer and the hole injection barrier between the hole injection layer and the buffer layer.
US08884277B2 Thick film conductive composition and use thereof
The invention relates to a thick film conductive composition comprising metal particles wherein the specific surface area of the silver particles measured by BET according to ISO 9277 is equal to or more than 1.8 m2/g; manganese oxide; glass particles; and an organic vehicle.
US08884273B1 Process for group III-V semiconductor nanostructure synthesis and compositions made using same
Methods for producing nanostructures, particularly Group III-V semiconductor nanostructures, are provided. The methods include use of novel Group III and/or Group V precursors, novel surfactants, oxide acceptors, high temperature, and/or stable co-products. Related compositions are also described. Methods and compositions for producing Group III inorganic compounds that can be used as precursors for nanostructure synthesis are provided. Methods for increasing the yield of nanostructures from a synthesis reaction by removal of a vaporous by-product are also described.
US08884270B2 Vertical junction field effect transistors with improved thermal characteristics and methods of making
Vertical junction field effect transistors (VJFETs) having improved heat dissipation at high current flow while maintaining the desirable specific on-resistance and normalized saturated drain current properties characteristic of devices having small pitch lengths are described. The VJFETs comprise one or more electrically active source regions in electrical contact with the source metal of the device and one or more electrically inactive source regions not in electrical contact with the source metal of the device. The electrically inactive source regions dissipate heat generated by the electrically active source regions during current flow.
US08884269B2 Nitride-based semiconductor light emitting device
A nitride-based semiconductor light emitting device includes an anti-bowing layer having a composition of AlxGa1-xN (0.01≦x≦0.04), and a light emitting structure formed on the anti-bowing layer and including a first conductivity-type nitride semiconductor layer, an active layer, and a second conductivity-type nitride semiconductor layer.
US08884267B2 Light-emitting element with multiple light-emitting stacked layers
A light-emitting element, comprises: a first active layer, generating a first light comprising a first dominant wavelength, wherein the first active layer comprises a first quantum well comprising a first quantum-well band gap and a second quantum well comprising a second quantum-well band gap, and the first quantum well and the second quantum well are alternately stacked to form the first active layer, wherein a difference between the first quantum-well band gap and the second quantum-well band gap is between 0.06eV and 0.1eV, and each of the first quantum-well and the second quantum-well is devoid of a barrier; and a second active layer on the first active layer, generating a second light comprising a second dominant wavelength; wherein a difference between the first dominant wavelength and the second dominant wavelength is 150nm to 220nm.
US08884260B2 Phase change memory element
A phase-change memory element with an electrically isolated conductor is provided. The phase-change memory element includes: a first electrode and a second electrode; a phase-change material layer electrically connected to the first electrode and the second electrode; and at least two electrically isolated conductors, disposed between the first electrode and the second electrode, directly contacting the phase-change material layers.
US08884258B1 Ultraviolet light source and methods
A device for providing ultraviolet light includes a shell for a portable device, wherein the shell includes an interior region and an exterior region, wherein the interior region is adapted to be disposed adjacent to the portable device, a power source configured to provide electrical power, a and an ultraviolet light source coupled to the power source and embedded into the exterior region of the shell, wherein the ultraviolet light source is configured to output the ultraviolet light in response to the electrical power.
US08884253B2 System for magnetic shielding
The invention relates to a system for magnetically shielding a charged particle lithography apparatus. The system comprises a first chamber, a second chamber and a set of two coils. The first chamber has walls comprising a magnetic shielding material, and, at least partially, encloses the charged particle lithography apparatus. The second chamber also has walls comprising a magnetic shielding material, and encloses the first chamber. The set of two coils is disposed in the second chamber on opposing sides of the first chamber. The two coils have a common axis.
US08884252B2 Diamond tools
A method comprising: selecting a diamond material; irradiating the diamond material with neutrons to increase toughness and/or wear resistance of the diamond material; and processing the diamond material into one or more diamond tool pieces, wherein the irradiating comprises irradiating the diamond material with neutrons having an energy in the range 1.0 keV to 12 MeV, wherein the irradiating comprises controlling energy and dosage of irradiation to provide the diamond material with a plurality of isolated vacancy point defects, the isolated vacancy point defects having a concentration in a range 1×1014 to 1×1020 vacancies/cm−3.
US08884249B2 Device for sterilizing closures for containers
An apparatus for sterilizing cap-like closures for closing bottles includes a conveying system to move the cap-like closures through a treatment zone in which the cap-like closures are exposed to ultraviolet radiation for sterilization, the treatment zone having ultraviolet radiation sources for emitting ultraviolet light. Within the treatment zone, the conveying system includes a rotor that can be driven to rotate about a vertical rotor axis, and closure holders formed on a periphery of the rotor. Each closure holder is oriented with a longitudinal extension thereof in a direction of the rotor axis. The closure holders are configured for moving the cap-like closures vertically from top to bottom through the treatment zone on a treatment section between a closure supply and a closure discharge.
US08884247B2 System and method for ex situ analysis of a substrate
A method and system for creating an asymmetrical lamella for use in an ex situ TEM, SEM, or STEM procedure is disclosed. The shape of the lamella provides for easy orientation such that a region of interest in the lamella can be placed over a hole in a carbon film providing minimal optical and spectral interference from the carbon film during TEM, SEM, or STEM procedure of chemical analysis.
US08884245B2 Corrector for the correction of chromatic aberrations in a particle-optical apparatus
The invention describes a corrector for the correction of chromatic aberrations in a particle lens, such as used in a SEM or a TEM. So as to reduce the stability demands on the power supplies of such a corrector, the energy with which the particle beam passes through the corrector is lower than the energy with which the beam passes through the lens to be corrected.
US08884241B2 Incident capacitive sensor
A capacitive sensor device for measuring radiation. The device includes two sensor regions and top plate structure. The sensor regions are of a material that generates electron-hole pairs when radiation strikes the material. A separation region is located between the two sensor regions. The capacitance between a sensor region and top plate is dependent upon radiation striking the sensor region. A blocking structure selectively and differentially blocks radiation having a parameter value in a range from the sensor region so as to differentially impact electron-hole pair generation of one sensor region with respect to electron-hole pair generation of the other sensor region at selected angles of incidence of the radiation.
US08884240B1 Position sensitive solid-state photomultipliers, systems and methods
An integrated silicon solid state photomultiplier (SSPM) device includes a pixel unit including an array of more than 2×2 p-n photodiodes on a common substrate, a signal division network electrically connected to each photodiode, where the signal division network includes four output connections, a signal output measurement unit, a processing unit configured to identify the photodiode generating a signal or a center of mass of photodiodes generating a signal, and a global receiving unit.
US08884237B2 Neutron detection
In exemplary embodiments, an apparatus, includes a first electrode, a second electrode, a first polygonal channel extending between the electrodes, the first channel having a first side having a center, and a second polygonal channel extending between the electrodes, the second channel having a second side contacting the first side, the second side having a center, wherein the center of the first side and the center of the second side are non-collinear in a direction perpendicular to a surface of the first side, and wherein the first and second channels do not have square cross sections perpendicular to longitudinal axes of the channels.
US08884236B2 Detector with active collimators
An apparatus and methods for detecting radiation. A plurality of substantially parallel active collimation vanes are sensitive to the incident radiation for generating at least a first detection signal, and a rear detector detects incident radiation that passes between the substantially parallel active collimation vanes and generates a second detection signal. A processor receives and processes both the first and second detection signals. The active collimator vanes may be enclosed within a light-tight enclosure, and a first photodetector may be provided for detecting scintillation arising at the active collimation vanes, while a second photodetector may be provided for detecting scintillation arising at the rear detector.
US08884232B2 Radiation detection device
A scintillator receives radiation and produces light. The scintillator is composed of columnar crystals arranged upright. Conical end portions of the columnar crystals are embedded in a resin layer formed on a light detection section. The resin layer, made from a thermosetting resin material, is heated and cured with the end portions embedded therein. Because a refractive index of the resin layer is lower than that of the columnar crystals, average refractive indices of respective layers between the columnar crystals and the light detection section change continuously. The resin layer prevents the end portions from damage and improves efficiency of incidence on the light detection section.
US08884227B2 Sensor
A sensor includes a first electrode, a second electrode, a ferroelectric element that is disposed between the first electrode and the second electrode and that has a ferroelectric film formed of a ferroelectric substance, and a detector configured to read an electric charge generated in the ferroelectric element. The detector performs reading by applying a first voltage for aligning polarization directions of the ferroelectric film and a second voltage for reversing polarization of at least part of the ferroelectric film whose polarization directions have been aligned.
US08884220B2 Multiple channel detection for time of flight mass spectrometer
An ion detector for a Time of Flight mass spectrometer is disclosed comprising a single Microchannel Plate 1 which is arranged to receive ions 2 and output electrons 3. The electrons 3 are directed onto an array of photodiodes 4 which directly detects the electrons 3. The output from each photodiode 4 is connected to a separate Time to Digital Converter provided on an ASIC 5.
US08884219B2 Differential mobility spectrometer with asymmetrically oscillating driving electrical field
A method of operating a differential mobility spectrometer includes an ionization chamber, a filter channel and a detection region. In the ionization chamber, analyte ions are produced from a sample, the so-obtained ions are then subjected in the filter channel to a time-varying electric field. The time-varying electric field has a longitudinal field component drawing the analyte ions from the ionization chamber through the filter channel into the detection region and a transversal field component, which is the superposition of an asymmetrically oscillating transversal field causing the analyte ions to move to and fro in transversal direction and a compensation field for selecting a species of analyte ions by substantially canceling the average transversal velocity of the selected species. Analyte ions of the selected species having passed through the filter channel are collected in the detection region and a detection signal responsive to the number of analyte ions collected is generated as a function of the compensating field. The longitudinal field component oscillates in longitudinal direction in such a way that it imparts to the analyte ions on average a non-zero longitudinal velocity in direction of the detection region while it causes them, on a shorter time scale, to move to and fro in longitudinal direction in the filter channel.
US08884216B2 Gas detection and quantification method using a pulsed neutron logging tool
A method of formation evaluation using a pulsed neutron tool. The approach removes the effect of formation hydrogen index (HI) from the nuclear response of the tool. It can be used for gas detection and quantification, as well as for other fluids. It can also be used to improve a formation hydrogen index (HI) measurement.
US08884212B2 Neutron multiplicity counting
Each pulse of a pulse sequence received from a neutron detector is set as a trigger pulse triggering a predefined gate, the multiplicity of pulses within this gate is determined, the pulse having triggered the gate is assigned to a multiplicity category corresponding to this multiplicity of pulses and the trigger-to-predecessor distances from the trigger pulse to pulses preceding the trigger pulse within a certain range in the pulse sequence are determined. The range within which one looks for predecessor pulses of each trigger pulse exceeds the dead time of the neutron detector. For each multiplicity category, the number of trigger pulses assigned thereto is determined. For each multiplicity category, one builds, based upon the trigger-to-predecessor intervals determined, a distribution in time after an arbitrary preceding pulse of trigger pulses assigned to that specific multiplicity category. Based upon the multiplicity-specific distribution, one estimates, for each multiplicity category, the number of trigger pulses lost due to neutron detector dead time that would have been assigned to the multiplicity category. When the estimated number of lost trigger pulses is known, the number of trigger pulses assigned to each multiplicity category is accordingly corrected. As trigger pulses could have been assigned to a wrong multiplicity category due to missing pulses inside the triggered gates, the number of trigger pulses assigned to each multiplicity category may additionally be corrected for that using a similar technique.
US08884210B2 Spectrum information measurement method, color sensor and virtual slide device
A spectrum information measurement method may include steps of; controlling a reference pixel accumulating charges based on an amount of light irradiated from a test specimen; controlling a plurality of measurement pixels accumulating the charge based on an amount of light that is irradiated from the test specimen and has a prescribed wavelength; generating and outputting a reference signal based on an amount of change in the charge that is accumulated in the reference pixel over the prescribed measurement time; generating and outputting a plurality of measurement signals based on an amount of change in the charge that is accumulated in each of the plurality of measurement pixels over the prescribed measurement time; determining whether or not any one or more of the plurality of measurement signals is greater than the reference signal, and determining that the measurement signal that is greater than the reference signal includes saturated output.
US08884206B2 Solid-state imaging element, driving method, and electronic apparatus
Disclosed herein is a solid-state imaging element including: a plurality of unit pixels each having a photoelectric conversion part, a transfer part that transfers a charge generated by the photoelectric conversion part to a predetermined region, and a draining part that drains a charge in the predetermined region; a light shielding film being formed under an interconnect layer in the unit pixels and shield, from light, substantially the whole surface of the plurality of unit pixels except a light receiving part of the photoelectric conversion part; and a voltage controller controlling a voltage applied to the light shielding film. The voltage controller sets the voltage applied to the light shielding film to a first voltage in charge draining by the draining part and sets the voltage applied to the light shielding film to a second voltage higher than the first voltage in charge transfer by the transfer part.
US08884201B2 Systems and methods for fabrication of thermoplastic components
A method of fabricating a thermoplastic component using inductive heating is described. The method includes positioning a plurality of induction heating coils to define a process area for the thermoplastic component, wherein the plurality of induction heating coils comprises a first set of coils and a second set of coils. The method also includes controlling a supply of electricity provided to the plurality of inductive heating coils to intermittently activate the coils. The intermittent activation is configured to facilitate prevention of electromagnetic interference between adjacent coils.
US08884199B2 Electric power system for electric induction heating and melting of materials in a susceptor vessel
Apparatus and process for heating and melting a material in a susceptor vessel are provided wherein phase synchronized ac voltage is supplied from a separate power source to each one of at least two induction coils in separate zones around the vessel. Power magnitude from each source to an induction coil is controlled by pulse width control of the source's output voltage. Output frequency from each source is either fixed or variable based upon the electrically conductive state of the material. Optional electromagnetic stirring is achieved by establishing a phase shift between the voltage outputs of the power supplies after the material in the susceptor vessel has melted.
US08884198B2 Parametric temperature regulation of induction heated load
A fuel delivery system for a vehicle includes a fuel injector that dispenses heated fuel flow and controls the temperature of the heated fuel within a desired temperature range. Fuel flowing through the example fuel injector is inductively heated by a valve element sealed with the fuel flow. A driver controller detects changes in temperature by monitoring changes in parameters that vary responsive to temperature in the material of the heated element. Changes in the material responsive to temperature are utilized to tailor input into the heated element to maintain a desired temperature of the heated element and thereby the temperature of the fuel.
US08884197B2 Induction cook top with heat management system
An indoor or outdoor induction cook top with a heat management system is disclosed. The cook top controls heat generated by various components, including the electronic controller, mechanical controls, and the induction generators. The heat management system provides precise temperature control and an efficient way of removing heat from the cooktop. The cook top construction provides the ability to incorporate a smooth ceramic glass cook top and a number of induction hobs in multiple arrangements. The cook top also features a reduction in the number of components, the efficient removal of generated heat, the reduction of noise, an increase in performance and a barrier airflow director. Consequently, the cook top may be installed in a countertop without the need for venting above the counter.
US08884196B2 Cooking device for a cooking container
The invention relates to a cooking device (1, 12) for a cooking container (10, 11), a) wherein the cooking device (1, 12) comprises at its lower surface (20) a curved, especially concave, cooking surface (2) adapted to the form of the cooking container (10, 11), b) wherein the cooking surface (2) comprises a first (2a) and a second (2b) partial surface, c) wherein the cooking container (10, 11) comprises a first area (20a) adjacent to the first partial surface (2a) and a second area (20b) adjacent to the second partial surface (2b), d) wherein the first area (20a) is heated by a first induction element (3) and the second area (20b) is heated by a second induction element (4), e) wherein each induction element (3, 4) comprises an individual heat sensor (3d, 4d) and f) wherein at least the second induction element (4) can be controlled independently from the first induction element (3).
US08884193B2 Easily removable combustion tube
A combustion tube mounting system releasably mounts a combustion tube to an aperture in the floor of a furnace housing. The combustion tube has a base assembly with a cam and can be manually or automatically unlocked by cam pins in the floor for selectively engaging the cam for lowering the combustion tube from the floor of the furnace. When a new combustion tube is placed on the lower seal assembly and raised, it automatically aligns and engages the upper furnace seal and engages cams on the floor of the furnace housing which lock the combustion tube in place as it is introduced into the furnace.
US08884192B2 Heater and image heating apparatus having the heater installed therein
The image heating apparatus includes first and second lines having a first and second heat generation blocks, the first and second lines being disposed at different positions in a transverse direction, wherein the first and second lines are arranged so that a whole of first heat generation block in the first line and a whole of second heat generation block in the second line overlap with each other in the longitudinal direction, and a whole of second heat generation block in the first line and a whole of first heat generation block in the second line overlap with each other in the longitudinal direction. By the virtue of the present invention, it achieves to be capable of suppressing a temperature rise in a non-sheet feeding area in a case of printing a sheet smaller in size than a maximum size supported by the image heating apparatus.
US08884189B2 Welding power to auxiliary power conversion system and method
Methods and systems for manufacturing and using the auxiliary power conversion unit, which is capable of being remotely located from a welding power supply unit during a welding operation, are provided. In some embodiments, the auxiliary power conversion is capable of outputting DC as well as AC power, capable of outputting multiple voltages consistent with the demands of typical auxiliary tools, such as a hand grinder or a light. In certain embodiments, the power conversion unit may be a stand-alone system or may be incorporated into a device, such as a wire feeder, which is configured to derive power from the arc potential. The power conversion unit may contain control and processing electronics that may include a controller, a processor, memory, and so forth.
US08884184B2 Polymer tubing laser micromachining
An apparatus for athermal ablation of a workpiece. The apparatus may include a laser device to direct a laser beam at the workpiece to remove a plurality of sections from the workpiece by athermal ablation. The removal may occur in a plurality of discrete motions that cause the laser beam to trace along outer perimeters of the sections in a specific order maintaining mechanical stability of the plurality of sections. The apparatus may further include a process gas nozzle to deliver process gas coaxially with the laser beam to clear debris and cool the workpiece, and a workpiece holder to hold and maneuver the workpiece during the removal of the plurality of sections.
US08884183B2 Welding process and a welding arrangement
A welding arrangement and a welding process for forming a weld seam between two edge portions, wherein the edge portions form a Y joint having a root portion and a bevel portion, said root portion being welded by a hybrid laser electric arc welding process including directing a laser beam and an electric arc in a single interaction zone of plasma and molten metal. A hybrid laser electric arc welding head and welding submerged arc welding head are arranged on a common carrier structure for welding the Y joint.
US08884182B2 Method of modifying the end wall contour in a turbine using laser consolidation and the turbines derived therefrom
A method of modifying an end wall contour is provided. The method includes creating a weld pool using a laser, adding a metal or a ceramic powder or a wire filler to the melt pool and modifying the part of the turbine in a manner that results in a change of about 0.005 to about 50 volume percent in the part of the turbine. The weld pool is created on a turbine component and contains molten metal or ceramic derived as a result of a heat interaction between the laser and the turbine component.
US08884176B2 HVDC breaker and control apparatus for controlling an HVDC breaker
The invention relates to an HVDC breaker (300) comprising at least two individually controllable HVDC breaker sections (305) connected in series, wherein the HVDC breaker is arranged in a manner so that the number of HVDC breaker sections tripped upon tripping of the HVDC breaker depends on the operational event in response to which the tripping occurs. The invention further relates to a control apparatus (400) for controlling the HVDC breaker, as well as to a method of breaking an HVDC line. The method comprises receiving (500) a system status signal indicative of an operational event requiring the breaking of the HVDC line, and determining (505) the number of HVDC breaker sections required for the breaking.
US08884172B2 Keypad apparatus for portable communication device
A keypad apparatus for a portable communication device in which a plurality of pressurizing protrusions are integrated with a plurality of dome switches is provided. To this end, the keypad apparatus includes a keypad comprising a plurality of key buttons, a front frame provided on a top surface of the keypad, a light path provided on a bottom surface of the keypad, and a plurality of dome switches provided on a bottom surface of the light path, such that a respective plurality of pressurizing protrusions are integrated with the plurality of dome switches on top surfaces of the plurality of dome switches.
US08884170B2 Handheld electronic luggage scale
A hand-held electronic luggage scale includes a handle designed to be held generally horizontally, and a hook supported by the handle, which extends generally vertically below the handle. The handle houses an electronic scale, the electronic scale connected to the hook for calculating a weight of an object suspended from the hook. The hook may be metal and have a rubber and/or plastic exterior. A touch screen display may be provided in a top surface of the handle that displays the calculated weight from the electronic scale component. The touch screen display may include an icon representing a virtual control button that controls a user-selectable setting, and provides haptic feedback when the user-selectable setting changes due to a user pressing the virtual control button for a predetermined period of time. The touch screen display may include icons that control power, illumination, units of measurement, and/or other functionality.
US08884168B2 Selectively conductive EMI gaskets
A fabric over foam electromagnetic interference gasket has a body of indefinite length, and includes a layer of dielectric material thereon. The gasket may be compressed between two substrates and provide electrical conductivity in one axis and EMI shielding and nonconductivity in a perpendicular axis.
US08884164B2 Circuit board assembly with flexible printed circuit board and reinforcing plate
A circuit board assembly includes a flexible circuit board, a dielectric layer and a reinforcing plate. The flexible circuit board includes a surface. A copper plating layer is positioned on the surface. The copper plating layer includes a circuit portion and a grounding portion. The circuit portion is entirely covered by the dielectric layer. The grounding portion is exposed outside the dielectric layer. The dielectric layer includes a bonding portion. The reinforcing plate includes a connection surface. The connection surface defines a cavity spatially corresponding to the bonding portion. The connection surface also includes an extending portion which is bulgy with respect to a bottom surface of the cavity. The extending portion spatially corresponds to the grounding portion. The bonding portion is received in the cavity with the extending portion in contact with and electrically connecting to the grounding portion by means of a conductive adhesive.
US08884163B2 Skin cured PTFE wire and cable
A wire having a conductor and an insulation where the insulation has a first inner layer of an uncured material and a second outer layer of a cured material.
US08884158B2 Solar cell and solar cell module
A solar cell and a solar cell module including a plurality of solar cells are discussed. The solar cell according to an embodiment includes a substrate of a first conductive type, an emitter layer of a second conductive type opposite the first conductive type disposed on the substrate, a plurality of first electrodes electrically connected to the emitter layer, a second electrode electrically connected to the substrate, a first current collector electrically connected to the plurality of first electrodes, and a second current collector electrically connected to the second electrode. The second current collector includes a plurality of second electrode current collectors electrically connected to the second electrode, and a current collector connector for connecting the plurality of second electrode current collectors to one another.
US08884156B2 Solar energy harvesting device using stimuli-responsive material
A solar energy harvesting system including a sunlight concentrating member (e.g., a lens array) for focusing direct sunlight at predetermined focal points inside a waveguide containing a stimuli-responsive material (SRM) that is evenly distributed throughout the waveguide material such that the SRM assumes a relatively high transparency state away from the focused sunlight, and small light-scattering portions of the SRM change to a relatively opaque (light scattering) state only in focal zone regions adjacent to the concentrated sunlight. The outer waveguide surfaces are locally parallel (e.g., planar) and formed such that sunlight scattered by the light-scattering SRM portions is transmitted by total internal reflection through the remaining transparent waveguide material, and outcoupled to one or more solar energy receivers (e.g., PV cells) that are disposed outside the waveguide (e.g., along the peripheral edge).
US08884149B2 Musical measurement stimuli
Systems and method for performing adaptive audio signal processing using music as a measurement stimulus signal. A musical stimuli generator may be used to generate musical stimulus signals composed to provide a stimulus with a spectrum that is substantially dense, and ideally white or pink, over a selected frequency range, so that all frequencies of interest are stimulated. The musical stimuli generator may generate melodically pleasing musical stimulus signals using music clips that include any of: a chromatic sequence, a chromatic sequence including chromatic tones over a plurality of octaves, a chromatic sequence including chromatic tones over a selected plurality of octaves, or an algorithmically composed chromatic sequence, to cover a selected frequency range. The musical stimulus signal may be generated as sound into the environment of use. An audio input picks up the sound from the environment, and a sound processor uses the received musical stimulus signal to determine a transfer function.
US08884148B2 Systems and methods for transforming character strings and musical input
Systems and methods for transforming character strings and musical input are provided herein. According to some embodiments, methods for transforming character strings into musical output may include executing instructions stored in memory via a processor to determine a scheme for converting character strings into musical output, receive the character string, parse the character string into character segments, and convert the character segments into individual musical notes according to the scheme to create the musical output.
US08884146B2 Internet system for monitoring progress of a music student
A method of utilizing the Internet to permit music teachers to measure and document the progress of their music students without infringing the copyright of the owners of the music the students are learning. In order to avoid copyright infringement the method assures that all performances of the copyrighted works be made in private and not displayed publicly. In a preferred embodiment the method includes the creation of a number of secure private Internet systems, one for each student, with each system limited to a studio administrator, the student, his teacher, and a limited number (preferably less than 25) of designated third parties such as family members and friends of the student. In other preferred embodiment student performances are made available to the general public through the Internet for a fee which is shared with the owner, if any, of the copyright.
US08884145B1 Percussion device for cajon
A percussion device of a cajon includes a base with a bottom plate, two upright columns on the same side of the bottom plate, a pedal pivotally coupled to the bottom plate, a pivot horizontally pivoted to the top of the two upright columns, a hammer fixed to an outer segment of the pivot, a restoring tension spring for restoring the position of the pivot after rotation, a link member coupled between first and second ends of the pedal. When the second end of the pedal is stepped downward, the first end is warped to link the link member to rotate the pivot while stretching the restoring tension spring, and the hammer swings with the rotation of the pivot. After the pedaling force disappears, the restoring tension spring pulls the pivot to rotate and link the link member to swing the first end downward and restore its original position.
US08884142B1 Maize hybrid X18C105
A novel maize variety designated X18C105 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X18C105 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18C105 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X18C105, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18C105. This invention further relates to methods for producing maize varieties derived from maize variety X18C105.
US08884140B1 Plants and seeds of hybrid corn variety CH130037
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH130037. The invention thus relates to the plants, seeds and tissue cultures of the variety CH130037, and to methods for producing a corn plant produced by crossing a corn plant of variety CH130037 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH130037.
US08884134B2 Plants and seeds of hybrid corn variety CH715748
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH715748. The invention thus relates to the plants, seeds and tissue cultures of the variety CH715748, and to methods for producing a corn plant produced by crossing a corn plant of variety CH715748 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH715748.
US08884129B2 Plants and seeds of hybrid corn variety CH514236
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH514236. The invention thus relates to the plants, seeds and tissue cultures of the variety CH514236, and to methods for producing a corn plant produced by crossing a corn plant of variety CH514236 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH514236.
US08884126B2 Corn variety DE811ASR(BC5)
This invention relates to polynucleotide sequences encoding a gene that can confer resistance to the plant pathogen Colletotrichum, which causes anthracnose stalk rot, leaf blight and top dieback in corn and other cereals. It further relates to plants and seeds of plants carrying chimeric genes comprising the polynucleotide sequences, which enhance or confer resistance to the plant pathogen Colletotrichum, and processes of making the plants and seeds. The invention further presents sequences that can be used as molecular markers that in turn can be used to identify the region of interest in corn lines resulting from new crosses and to quickly and efficiently introgress the gene from corn lines carrying the gene into other corn lines that do not carry the gene, in order to make them resistant to Colletotrichum and resistant to stalk rot.
US08884121B1 Soybean cultivar 23272101
A soybean cultivar designated 23272101 is disclosed. The invention relates to the seeds of soybean cultivar 23272101, to the plants of soybean cultivar 23272101, to the plant parts of soybean cultivar 23272101, and to methods for producing progeny of soybean cultivar 23272101. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 23272101. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 23272101, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 23272101 with another soybean cultivar.
US08884119B1 Soybean variety XBP14004
A novel soybean variety, designated XBP14004 is provided. Also provided are the seeds of soybean variety XBP14004, cells from soybean variety XBP14004, plants of soybean XBP14004, and plant parts of soybean variety XBP14004. Methods provided include producing a soybean plant by crossing soybean variety XBP14004 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP14004, methods for producing other soybean varieties or plant parts derived from soybean variety XBP14004, and methods of characterizing soybean variety XBP14004. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP14004 are further provided.
US08884116B2 Soybean variety A1037458
The invention relates to the soybean variety designated A1037458. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1037458. Also provided by the invention are tissue cultures of the soybean variety A1037458 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1037458 with itself or another soybean variety and plants produced by such methods.
US08884113B2 Soybean variety A1026632
The invention relates to the soybean variety designated A1026632. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026632. Also provided by the invention are tissue cultures of the soybean variety A1026632 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026632 with itself or another soybean variety and plants produced by such methods.
US08884108B2 Soybean variety A1026416
The invention relates to the soybean variety designated A1026416. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026416. Also provided by the invention are tissue cultures of the soybean variety A1026416 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026416 with itself or another soybean variety and plants produced by such methods.
US08884104B1 Canola line NS6213
A novel canola variety designated NS6213 and seed, plants and plant parts thereof. Methods for producing a canola plant that comprise crossing canola variety NS6213 with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into NS6213 through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby. Hybrid canola seed, plant or plant part produced by crossing the canola variety NS6213 or a locus conversion of NS6213 with another canola variety.
US08884098B2 Expression cassettes for regulation of expression in monocotyledonous plants
The present invention relates to expression cassettes comprising at least one transcription regulating nucleotide sequence obtainable from the group of genes of monocotyle-donous plants consisting of caffeoyl-CoA-O-methyltransferase genes, C8,7-sterol isomerase genes, hydroxyproline-rich glycoprotein (HRGP) genes, lactate dehydrogenase genes, and chloroplast protein 12 like genes. More preferably the transcription regulating sequences are obtainable from Zea mays or Oryza sativa. The transcription regulating sequences are especially useful for root/kernel-preferential, leaf/endosperm-preferential, root/silk/kernel-preferential, or constitutive expression.
US08884089B2 Process for producing olefins
The present invention provides a process for producing olefins, comprising: a. cracking an ethane-comprising feed in a cracking zone under cracking conditions to obtain at least olefins and hydrogen; b. converting an oxygenate feedstock in an oxygenate-to-olefin zone to obtain at least olefins; wherein at least part of the oxygenate feedstock is obtained by providing hydrogen obtained in step a) and a feed containing carbon monoxide and/or carbon dioxide to an oxygenate synthesis zone and synthesizing oxygenates. In another aspect the invention provides an integrated system for producing olefins.
US08884087B2 Block coordination copolymers
The present invention provides compositions of crystalline coordination copolymers wherein multiple organic molecules are assembled to produce porous framework materials with layered or core-shell structures. These materials are synthesized by sequential growth techniques such as the seed growth technique. In addition, the invention provides a simple procedure for controlling functionality.
US08884084B2 Process for the manufacture of halocarbons and selected compounds and azeotropes with HF
A liquid phase process is disclosed for producing halogenated alkane adducts of the formula CAR1R2CBR3R4 (where A, B, R1, R2, R3, and R4 are as defined in the specification) which involves contacting a corresponding halogenated alkane, AB, with a corresponding olefin, CR1R2═CR3R4 in a dinitrile or cyclic carbonate ester solvent which divides the reaction mixture into two liquid phases and in the presence of a catalyst system containing (i) at least one catalyst selected from monovalent and divalent copper; and optionally (ii) a promoter selected from aromatic or aliphatic heterocyclic compounds which contain at least one carbon-nitrogen double bond in the heterocyclic ring. When hydrochlorofluorocarbons are formed, the chlorine content may be reduced by reacting the hydrochlorofluorocarbons with HF.Azeotropes of CClF2CH2CF3 with HF and azeotropes of CF3CH2CHF2 with HF are also disclosed; as are process for producing such azeotropes.
US08884081B2 Integrated process for producing acetic acid and alcohol
The present invention relates generally to processes for producing ethanol and acetic acid and, in particular, to a process for integrating an ethanol production process with an acetic acid production process.
US08884080B2 Reduced energy alcohol separation process
Recovery of alcohols, in particular ethanol, from a crude ethanol product obtained from the hydrogenation of acetic acid using a reduced energy process. The crude ethanol product may be fed to a distillation column in which a substantial portion of the water is removed with the acetic acid in the residue. The ethanol product is obtained from the distillate.
US08884077B2 Hydroconversion of renewable feedstocks
A hydrocarbon conversion process comprises contacting a renewable feedstock under hydroprocessing conditions with a bulk catalyst to form oleochemicals such as fatty alcohols, esters, and normal paraffins. Advantageously, the reaction conditions can be selected to directly convert the renewable feedstock to the desired product(s).
US08884075B2 Process for producing phenol
In a process for the dehydrogenation of cyclohexanone to produce phenol, cyclohexanone is contacted in a reaction zone under dehydrogenation conditions with a dehydrogenation catalyst comprising (i) a support comprising silica; and (ii) a dehydrogenation component comprising at least one metal selected from Group 10 of Periodic Table of Elements. Contact of the dehydrogenation catalyst with the cyclohexanone is then terminated and the dehydrogenation catalyst is contacted with an inert gas and/or hydrogen at a temperature of at least 300° C. Contact of the dehydrogenation catalyst with additional cyclohexanone is subsequently reestablished.
US08884074B2 Method and device for producing dimethyl ether from methanol
A process produces dimethyl ether (DME) from methanol (MeOH). The process includes charging a feed mixture consisting of raw MeOH and a process-internally obtained return flow substantially consisting of unconverted MeOH and reaction water to an MeOH column. The feed mixture is evaporated in the MeOH column to form a first distillate substantially consisting of vaporous MeOH. The first distillate is supplied to a reactor and the MeOH is converted to DME by splitting off water in the reactor so as to form a reaction mixture. The reaction mixture is withdrawn from the reactor, charged to a mixture column and separated into a bottom product substantially consisting of water and a second distillate substantially consisting of DME and MeOH. The second distillate is separated in a DME column into a third distillate substantially consisting of DME, a bottom product consisting essentially of water-poor MeOH, and uncondensable gases discharged overhead. The bottom product is either supplied to a top of the MeOH column or mixed with another bottom product withdrawn from a forerun column.
US08884072B2 Mitigation of fouling in hydroformylation processes by water addition
The extraction process for removing metal salts from an organic hydroformylation reaction fluid (“HRF”) prior to returning the HRF to a reaction zone of a hydroformylation process, the extraction process comprising the step of contacting the HRF with an aqueous buffer solution, is improved by contacting the HRF with water in addition to that present in the aqueous buffer solution, i.e., with added water.
US08884071B2 Hydroformylation method having improved catalyst stability in reaction
Disclosed is a hydroformylation method having improved catalyst stability in a reaction. Advantageously, provided is a hydroformylation method in which a specific α,β-unsaturated carbonyl compound is incorporated during a hydroformylation reaction to prevent alkyl phosphite decomposed from a phosphite ligand from acting as a catalyst poison, thereby improving a yield of reaction and inhibiting decomposition of ligand and catalyst.
US08884070B2 Energy efficient synthesis of aliphatic aldehydes from alkenes and carbon dioxide
Provided is a process for producing an aldehyde from an alkylene. The process includes (a) photocatalytically dehydrogenating at least one alkane to obtain a mixture comprising at least one olefin and hydrogen, (b) adding carbon dioxide and hydrogen to the mixture, and (c) hydroformylating the olefin to at least one aldehyde. The process also includes converting carbon dioxide and hydrogen into water and carbon monoxide prior to the hydroformylating. In addition, the conversion of carbon dioxide and hydrogen into water and carbon monoxide is performed by a reverse water gas shift reaction.
US08884069B2 Production of aldehydes by oxidation in aqueous medium with selective recovery of the product by means of pervaporation
A process for the preparation of an aromatic aldehyde by means of the oxidation of the corresponding starting compound in aqueous medium, and separation of said aldehyde from said medium by pervaporation is disclosed together a plant for its carrying out. Advantageously, the process of the present invention allows control of oxidation reaction and recovery of the product with high selectivity and purity. Among others, benzaldehyde, anisaldehyde and vanillin can advantageously be prepared by this process.
US08884067B2 Phenol and cyclohexanone mixtures
In a process for producing phenol and cyclohexanone, a feed comprising cyclohexylbenzene is oxidized to produce an oxidation reaction product comprising cyclohexyl-1-phenyl-1-hydroperoxide. At least a portion of the oxidation reaction product is then cleaved to produce a cleavage reaction product comprising phenol, cyclohexanone, and at least one contaminant. At least a portion of the cleavage reaction product is contacted with an acidic material to convert at least a portion of the at least one contaminant to a converted contaminant and thereby produce a modified reaction product. The cleavage reaction product may comprise 1 wt %-30 wt % phenol; 1 wt %-30 wt % cyclohexanone; and 0.1 wt % to 10 wt % of at least one of water, bicyclohexane, cyclohexenylbenzene, methylcyclopentanone, 1-phenylhexan-1-one, cyclohexyldione, cyclohexanol, cyclohexenone, hydroxycyclohexanone, benzoic acid, phenyl cyclohexanol, hexanal and 1-phenyl-6-hydroxyhexan-1-one, wherein the wt % s are based upon the total weight of the mixture.
US08884066B2 Process for preparing isophorone in the presence of at least one defoamer in the wastewater column in the workup section
The invention relates to a process for preparing isophorone (3,5,5-trimethyl-2-cyclohexen-1-one) in the presence of at least one defoamer in the wastewater column in the workup section.
US08884064B2 Method of separating off magnetizable catalyst particles by means of magnetic filters
The present invention relates to a process comprising at least the steps (A) chemical reaction of at least one organic compound in the presence of at least one heterogeneous catalyst in a reaction mixture and (B) removal of the at least one heterogeneous catalyst by means of a magnetic filter, and also the use of a magnetic filter for separating off catalyst particles in a process for the hydrogenation of at least one organic compound.
US08884062B2 Aminodihydrothiazine derivatives substituted with a cyclic group
This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R1 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; R2a and R2b are each independently hydrogen, optionally substituted lower alkyl or optionally substituted acyl; R3a, R3b, R3c and R3d are each independently hydrogen, halogen, hydroxy or optionally substituted lower alkyl etc.; a pharmaceutically acceptable salt or solvate thereof, which is useful for treating diseases induced by production, secretion and/or deposition of amyloid β protein.
US08884061B2 Compositions and methods of use of electron transport system inhibitors
The invention provides compounds of the formula: or a pharmaceutically acceptable salt thereof, where m, n, R1, R2, R3 R4, R5, R6, R7 are those defined herein. The invention also provides pharmaceutical compositions comprising a compound of the invention, methods for using compounds and/or pharmaceutical compositions of the invention, and methods for synthesizing compounds of the invention.
US08884060B2 Process of preparing chiral diacylhydrazine ligands
The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements.
US08884056B2 Anaerobic conversion of 4-carboxybenzaldehyde in ionic liquids
A method of decreasing an amount of an aromatic aldehyde in a product is described. The method includes reacting the aromatic aldehyde in the presence of a reaction medium comprising a nucleophilic solvent, or an ionic liquid and a carboxylic acid, the reaction taking place in the absence of a hydrogenating agent and an oxidizing agent, to form aromatic carboxylic acid, an aromatic alcohol, or both.
US08884055B2 Process for producing terephthalic acid
A solid terephthalic acid composition and a process for producing terephthalic acid from para-xylene. The process comprises forming a mixture comprising the para-xylene, a solvent, a bromine source, and a catalyst; and oxidizing the para-xylene by contacting the mixture with an oxidizing agent at oxidizing conditions to produce a solid oxidation product comprising terephthalic acid, para-toluic acid, 4-carboxybenzaldehyde. The solvent comprises a carboxylic acid having from 1 to 7 carbon atoms and an dialkyl imidazolium ionic liquid; and the catalyst comprises at least one of cobalt, titanium, manganese, chromium, copper, nickel, vanadium, iron, molybdenum, tin, cerium, and zirconium. The solid terephthalic acid composition comprises, less than about 4,000 ppm-wt 4-carboxybenzaldehyde content, and more than about 2,000 ppm-wt a para-toluic acid.
US08884049B2 Glycerol based polymer surface active chemistry and production
The invention provides a method of efficiently producing branched, cyclic glycerol-based polymer surface active products having ester and alkyl functional groups with a co-product as anti-biodegrading agent from inexpensive readily available glycerol monomer. The method involves polymerizing glycerol or glycerol with at least another monomer to multiple other monomers in the presence of particular amount of a strong base as the catalyst under a particular distillation environment. The polyol then undergoes esterification, alkylation and crosslinking in presence of particular amount of a catalyst under a particular low activity atmospheric environment. The glycerol-based polymer surface active products produced by the inventive method are beneficial for reducing lignin, extractives and rejects levels in pulping process of papermaking industry.
US08884048B2 Process for producing esters
A process for producing esters comprises esterifying an acid or anhydride with an excess of an alcohol to produce a crude ester, recovering excess alcohol from the crude ester and recycling recovered excess alcohol to the esterification reaction together with fresh alcohol. The process is improved by controlling the ratio of the amount of recycled alcohol and the amount of fresh alcohol in dependence on the level of impurities in the recycle alcohol. Further improvements come from feed forwarding fresh alcohol analysis results and from preheating the alcohol before loading into the reactor. Preferably, ester product quality is improved by stripping the alcohol for oxygen removal prior to esterification.
US08884047B2 N-substituted carbamic acid ester production method and isocyanate production method using the N-substituted carbamic acid ester
The present invention provides a method for producing N-substituted carbamic acid-O-aryl ester derived from a compound having an ureido group, the method comprising the step of carrying out esterification or esterification and transesterification from the compound having the ureido group and a hydroxy composition containing one type or a plurality of types of hydroxy compounds.
US08884040B2 Continuous method for producing fatty acid amides
The invention relates to a continuous method for producing fatty acid amides, according to which at least one fatty acid of formula (I), R3—COOH  (I) wherein R3 is an optionally substituted aliphatic hydrocarbon radical, is reacted with at least one amine of formula (II), HNR1R2  (II) wherein R1 and R2 are independently hydrogen or a hydrocarbon radical comprising between 1 and 100 C atoms, to form an ammonium salt, and said ammonium salt is then reacted to form a fatty acid amide, under microwave irradiation in a reaction pipe, the longitudinal axis of the pipe being oriented in the direction of propagation of the microwaves of a monomode microwave applicator.
US08884039B2 Crystallization of (20R) and (20S) analogs of 2-methylene-19-nor-24-dimethyl-1α,25-dihydroxyvitamin D3
Disclosed are methods of purifying (20R) and (20S) analogs of 2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 to obtain the (20R) and (20S) analogs in crystalline form. The method includes the steps of preparing a solvent of either diethyl ether or a mixture of 2-propanol and hexane, dissolving a product containing the (20R) and (20S) analog to be purified in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals.
US08884037B2 Method of reducing the value of an alkylene oxide production parameter in a process of making an alkylene oxide using a high efficiency catalyst
Methods of reducing the value of an alkylene oxide production parameter (such as alkylene oxide production rate) in a process of making an alkylene oxide by reacting an alkylene and oxygen over a high efficiency catalyst are shown and described. One method comprises reducing the concentration of oxygen in the reactor feed gas to reduce the value of the alkylene oxide production parameter.
US08884035B2 Production of tetrahydrofuran-2, 5-dimethanol from isosorbide
Disclosed herein are processes comprising contacting isosorbide with hydrogen in the presence of a first hydrogenation catalyst to form a first product mixture comprising tetrahydrofuran-2,5-dimethanol. The processes can further comprise heating the first product mixture in the presence of hydrogen and a second hydrogenation catalyst to form a second product mixture comprising 1,6-hexanediol. The first and second hydrogenation catalysts can be the same or different.
US08884028B2 Process for preparing alkyl 2-alkoxymethylene-4,4-difluoro-3-oxobutyrates
The present invention relates to a process for preparing a compound of formula (II) wherein R1 is CF3, CF2H or CFH2, and R2 and R3 are both independently C1-C6 alkyl, comprising a) reacting compounds of formula (IV), (V) and (VI) wherein R3 is as defined for the compound of formula (II), R4OM (V) wherein M is a lithium, sodium or potassium ion and R4 is C1-C6 alkyl, and (VI) wherein R1 is as defined for the compound of formula (II) and R5 is CrC6 alkyl, to form an enolate of formula (VII) wherein M is as defined for the compound of formula V and R1 and R3 are defined for the compound of formula (II), b) releasing the compound of formula (VIII) wherein R1 and R3 are as defined for the compound of formula (II), from the enolate of formula (VII) by means of an acid, and c) converting the compound of formula (VIII), in the presence of the salt formed from cation M and the anion of the acid in step b), to a compound of formula (II).
US08884024B1 Process for preparing benzisothiazolinones
N-alkylated 1,2-benzisothiazolin-3-ones can be prepared in good yield and good selectivity by reaction of the lithium salt of 1,2-benzisothiazolin-3-one with an electrophilic alkylating agent.
US08884017B2 2-heteroarylcarboxylic acid amides
The invention relates to novel 2-heteroarylcarboxamides, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
US08884013B2 Polymorphs of Dasatinib, preparation methods and pharmaceutical compositions thereof
Polymorph I of dasatinib monohydrate and Polymorph II of dasatinib, their preparation methods and pharmaceutical compositions containing the same are provided. These polymorphs have better physicochemical properties, are more stable and are more suitable for industrial scale production.
US08884012B1 Dye compound and method of making the compound
A perimidine coupler of formula 1: where R and R′ are substituents independently selected from the group consisting of a hydrogen atom, C1 to C4 alkyl or a solubilizing moiety comprising a substituted or unsubstituted C10 to C70 hydrocarbyl group. At least one of R and R′ is not a hydrogen atom or C1 to C4 alkyl. R″ and R′″ can be independently selected from the group consisting of a hydrogen atom, C1 to C6 alkyl groups and halogens.
US08884011B2 Nucleotide analogues as precursor molecules for antivirals
This invention relates to a purine or pyrimidine phosphonate compound of formula (I) or pharmaceutically acceptable salt thereof; wherein B, X, and R1-R3 are as defined in classes and subclasses herein. These compounds may be used as antiviral precursors. The invention also relates to therapeutic compositions of these compounds and their use for the preparation of a medication for testing and/or preventing a viral infection in a patient. The invention also provides methods for making these compounds. In particular, the invention provides an H-phosphinate precursor intermediate of formula (II) wherein B is a purine or pyrimidine base as defined herein and R1 is selected from the group comprising a hydrogen atom, and a methyl, ethyl, hydroxymethyl, hydroxyethyl and C1-6haloalkyl group.
US08884004B2 Process for the preparation of sucralose
The present invention provides a method for preparing colorless sucralose, wherein 4,1′,6′-trichloro-4,1′,6′-trideoxy-galactosucrose-6-acetate containing colored impurities formed during chlorination of sucrose-6-acetate is treated with sodium hypochlorite, where sodium hypochlorite acts both as a decolorizing agent and as a reagent for the ester hydrolysis.
US08884003B2 Method of chlorinating polysaccharides or oligosaccharides
A process for chlorinating polysaccharides or oligosaccharides, which comprises A) dissolving a polysaccharide or oligosaccharide in a solvent system which comprises at least one ionic liquid and B) reacting the polysaccharides or oligosaccharides with a chlorinating agent.
US08884002B2 Viscosity control in compositions comprising plant fiber materials
Pectinases, such as Pectinex™ Ultra SP-L (composed of the enzyme Polygatacturonase, a type of pectinase which is derived from Aspergillus aculeatus) or pectinmethylesterases were used to decrease or increase, respectively, the viscosity of fiber solutions, especially solutions with highly refined cellulosic thickeners, and particularly those made of highly refined cellulosic parenchyma cell wall fiber solutions. The enzyme can reduce the viscosity up to 95% or increase the viscosity 100 fold. At lower concentrations the enzyme requires up to a few days of reacting to reach the full reduction in viscosity. Pectinex™ Ultra SP-L has an optimum pH of 4.5-5 and a temperature optimum of 40° C. By controlling the viscosity available from the dried, treated highly refined cellulosic fiber compositions, tailored powder compositions can be provided that will provide precise viscosities when rehydrated in solutions at a constant concentration.
US08883998B2 siRNA targeting myeloid differentiation primary response gene (88) (MYD88)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for MYD88.
US08883997B2 Modulation of diacylglycerol acyltransferase 2 expression
Compounds, compositions and methods are provided for modulating the expression of diacylglycerol acyltransferase 2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding diacylglycerol acyltransferase 2. Methods of using these compounds for modulation of diacylglycerol acyltransferase 2 expression and for diagnosis and treatment of diseases and conditions associated with expression of diacylglycerol acyltransferase 2 are provided.
US08883995B2 Live attenuated influenza virus vaccines comprising microRNA response elements
The invention is directed to novel live attenuated influenza virus (LAIV) vaccines comprising one or more microRNA (miRNA) Response Element(s) (MRE) within an influenza virus genome. The MREs useful for the present invention can be derived from any miRNA which is highly expressed in influenza-targeted cells of an animal in need of vaccination but are not expressed or are expressed at very low levels in species (e.g., embryonated chicken eggs) or cell lines used for a large-scale vaccine production. This allows efficient vaccine production but renders the vaccine virus susceptible to attenuation in the influenza-targeted cells of vaccinated animals expressing a cognate miRNA.
US08883994B2 Switchable nucleic acid aptamer probe and uses thereof in tumor living cell detection and in vivo detection
A switch mode nucleic acid aptamer probe includes a probe main body, a fluorescence generating unit and a fluorescence quenching unit which are respectively connected to two ends of the probe main body. The probe main body includes a nucleic acid aptamer fragment with a function of specifically recognizing target tumor cell and a nucleic acid fragment linked to the nucleic acid aptamer fragment by a connection fragment with a length of 7˜15 nm so as to form a hairpin structure. The ability of competitive hybridization of the nucleic acid fragment with the nucleic acid aptamer fragment is weaker than that of the target tumor cell. The use of the probe of the invention can be at least one of specific detection of tumor living cell in buffer solution, effective detection of tumor living cell in serum, and real-time fluorescence imaging and intravital detection of tumor in living body.
US08883990B2 Asymmetric adapter library construction
The present invention provides methods and compositions for asymmetrically tagging a nucleic acid fragment using asymmetric adapters.
US08883988B2 Compositions for use in recombinational cloning of nucleic acids
The present invention relates to compositions and methods for use in recombinational cloning of nucleic acid molecules. In particular, the invention relates to nucleic acid molecules encoding one or more recombination sites or portions thereof, to nucleic acid molecules comprising one or more of these recombination site nucleotide sequences and optionally comprising one or more additional physical or functional nucleotide sequences. The invention also relates to vectors comprising nucleic acid molecules of the invention, to host cells comprising vectors or nucleic acid molecules of the invention, to methods of producing polypeptides using nucleic acid molecules of the invention, and to polypeptides encoded by these nucleic acid molecules or produced by methods of the invention. The invention also relates to the use of these compositions in methods for recombinational cloning of nucleic acids, in vitro and in vivo, to provide chimeric DNA molecules that have particular characteristics and/or DNA segments.
US08883987B2 Immune stimulating composition comprising bacterial chromosomal DNA fragments having methylated CpG sequences and non-toxic lipopolysaccharides
The present invention relates to immune stimulating composition comprising methylated bacterial chromosomal DNA fragments and non-toxic lipopolysaccharides. The composition of the present invention can be industrially applied the effective materials for treating cancers and adjuvant.
US08883985B2 Antibody-immobilized carrier, method of producing antibody-immobilized carrier, and use of said antibody-immobilized carrier
The present invention provides an antibody-immobilized carrier that can be used in antibody screening, a method of producing the antibody-immobilized carrier, and use of the antibody-immobilized carrier. Efficient antibody screening can be carried out particularly by an antibody-immobilized carrier including two or more antibody immobilized regions onto each of which a heavy-chain low-molecular-weight antibody and a light-chain low-molecular-weight antibody are separately immobilized, the two or more antibody immobilized regions each being included in an independent manner, the heavy-chain low-molecular-weight antibody including a heavy-chain variable region, the light-chain low-molecular-weight antibody including a light-chain variable region, the heavy-chain low-molecular-weight antibody and the light-chain low-molecular-weight antibody each being derived from an antibody recognizing a different antigen.
US08883981B2 Recombinant antibody composition
The present invention relates to a recombinant antibody composition having higher complement-dependent cytotoxic activity than a human IgG1 antibody and a human IgG3 antibody, wherein a polypeptide comprising a CH2 domain in the Fc region of a human IgG1 antibody is replaced by a polypeptide comprising an amino acid sequence which corresponds to the same position of a human IgG3 antibody indicated by the EU index as in Kabat, et al.; a DNA encoding the antibody molecule or a heavy chain constant region of the antibody molecule contained in the recombinant antibody composition; a transformant obtainable by introducing the recombinant vector into a host cell; a process for producing the recombinant antibody composition using the transformant; and a medicament comprising the recombinant antibody composition as an active ingredient.
US08883979B2 Anti-prolactin receptor antibody formulations
Provided are a wide concentration range, especially high concentration, substantially salt-free anti-prolactin receptor antibody formulations that are substantially isosmotic and of low viscosity.
US08883978B2 Antibodies to tumor endothelial marker 7R
Antibodies that specifically bind to an epitope on the extracellular domain of TEM7R are provided. Nucleic acids encoding such antibodies and cells capable of expressing such antibodies are also provided. The antibodies may be used in methods for treating tumors and for inhibiting angiogenesis in tumors.
US08883976B2 Antibodies against human tweak and uses thereof
An antibody binding to TWEAK comprising as heavy chain variable domain a CDR3H selected from the group consisting of SEQ ID NO: 8, 16 or 24.
US08883975B2 Antibodies against IL-18R1 and uses thereof
The invention provides anti-IL-18R1 antibodies and methods of using the same.
US08883973B2 Fc variants with altered binding to FcRn
The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.
US08883971B2 CTLA4 proteins and their uses
The present disclosure relates to CTLA4 proteins and uses of such proteins, for example to treat diseases associated with the dysregulation of immune responses.
US08883965B2 Compounds
The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of inter alia shock conditions as well as to a method for treatment of said conditions, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
US08883963B2 Peptidomimetics with glucagon antagonistic and GLP 1 agonistic activities
The present invention provides novel peptidomimetics, of formula (I), which primarily act as glucose dependent insulin secretagogues. Furthermore, it was found that these peptidomimetics showed glucagon receptor antagonistic activity, along with the GLP-I receptor agonistic activity.
US08883959B2 Method for manufacturing polyarylene sulfide resin
A method for producing a polyarylene sulfide resin, comprising: producing a slurry (I) containing a solid alkali metal sulfide by allowing a hydrous alkali metal sulfide, or a hydrous alkali metal hydrosulfide and an alkali metal hydroxide, and an aliphatic cyclic compound (c1) that can be ring-opened by hydrolysis to react with each other while conducting dehydration in the presence of a non-hydrolyzable organic solvent; adding an aprotic polar organic solvent after the production of the slurry (I) and distilling off water to conduct dehydration; and conducting polymerization by allowing a polyhaloaromatic compound (a), an alkali metal hydrosulfide (b), and an alkali metal salt (c2) of a hydrolysate of the compound (c1) to react with each other in the slurry (I) in a state where the amount of water existing in the reaction system is 0.02 moles or less relative to 1 mole of the aprotic polar organic solvent.
US08883957B2 Process for the preparation of polylactones and polylactams
The present invention relates to a process for the preparation of a lactone or lactam homopolymer, comprising the stage consisting in reacting a lactone or lactam with a nonpolymeric initiator comprising at least one hydroxyl or thiol functional group in a nonchlorinated solvent in the presence of a sulfonic acid of formula R—SO3H.It also relates to the polymer composition thus obtained and to its uses, in particular as antistatic additive.
US08883955B2 Method for producing polylactic acid
PROBLEMThere is provided a method for producing polylactic acid, which is capable of obtaining polylactic acid at low cost, and having high molecular weight.SOLUTIONA method for producing polylactic acid by polymerizing molten lactide using at least one reactor having plug flow characteristics with ξ(τ), calculated from the following FORMULA (1), of 0.3 or smaller: ξ(τ)=∫0∞(E(τ)×ABS(1−τ))dτ  (1) in the Formula (1), E(τ) is a residence time distribution function determined by impulse response by starch syrup having a viscosity of 3 Pa·s, and τ is ratio of elapsed time θ and mean residence time θ0.
US08883953B2 Copolymer, article including same, and display device including the article
A copolymer that includes a repeating unit A having a repeating unit represented by Chemical Formula 1, a repeating unit represented by Chemical Formula 2, or a combination thereof; and a repeating unit B having a repeating unit represented by Chemical Formula 3, a repeating unit represented by Chemical Formula 4, or a combination thereof, an article including the same, and a display device including the article.
US08883949B2 Binder resin for toner
A resin binder for a toner obtained by polycondensing a carboxylic acid component and an alcohol component in the presence of a lignin compound; a toner for electrophotography, containing the resin binder; and a method for producing a resin binder for a toner, including the step of polycondensing a carboxylic acid component and an alcohol component in the presence of a lignin compound. The resin binder for a toner of the present invention is suitably used as a resin binder of a toner used in development of latent images formed in electrophotography, electrostatic recording method, electrostatic printing method or the like.
US08883948B2 Methods for extensive dark curing based on visible-light initiated, controlled radical polymerization
Optimized methods to achieve extensive dark curing from a three-component visible light-initiated system though controlled radical polymerization and compositions useful in these optimized methods are provided. These compositions and methods are particularly suited for use in certain dental applications.
US08883943B2 Isoolefin polymers and process for preparing the same
The present invention relates to isoolefin polymers and process for preparing the same. The present invention especially discloses a polymerization process for the cationic polymerization of isoolefin monomers in an aqueous reaction medium, and isoolefin polymers obtained by such process. In one embodiment, the present invention relates to a polymerization process for the cationic polymerization of isoolefin monomers in an aqueous reaction medium, and isoolefin polymers obtained therefrom. In another embodiment, the present invention relates to a dispersion polymerization process for the cationic copolymerization of isoolefins with conjugated or non-conjugated diolefins and/or vinyl aromatic compounds, and copolymers obtained therefrom.
US08883941B2 Methods and apparatus for controlled single electron transfer living radical polymerization
This invention provides methods for controlled single electron transfer living radical polymerization (SET-LRP) of monomers with increased conversion, high molecular weights and low polydispersity by allowing the polymerization to proceed at low temperatures via a tubular reactor either made of copper or containing copper metal surface.
US08883940B2 Pressure management for slurry polymerization
Processes and systems for the production for pressure management of a polymerization product flowing from a loop polymerization reactor to a separation vessel in a slurry polymerization system are disclosed herein. For example, a process comprises withdrawing the polymerization product from a loop polymerization reactor, and conveying the withdrawn polymerization product to a separation vessel via a first pressure differential and a second pressure differential. The withdrawn polymerization product may flow through the first pressure differential before flowing through the second pressure differential, and the first pressure differential may be less than the second pressure differential.
US08883936B2 Curable composition
Provided is a curable composition having excellent water vapor permeability, which enables to protect a building from rainwater or moisture in the air and release the water accumulated on the side of the base of the building, to the outside. Also provided is a curable composition which has easy workability and is less likely to allow migration or exudation of a plasticizer to the surface of the cured product. Also provided is a liquid waterproof coating material having moisture permeability which contains the curable composition. The curable composition includes an organic polymer (I) that has less than one hydrolyzable silyl group per molecule on average and contains 5 to 80 wt % of oxyethylene units.
US08883935B2 High refractive index composition
A high refractive index composition comprising a reaction product of one or more first organic compounds capable of undergoing polymerization and one or more second compounds with high refractive index, and the method of making and using the composition.A composition comprising an organic compound obtained by coupling two reactive groups (a) and (b), wherein a. the reactive group (a) is Y—(CH2)n-M(O—R)3, wherein R is CH3, C2H5, C3H8, C4H10; and Y is —NH2, —COOH, —NCO, or epoxy; and wherein M is selected from the group consisting of Ti, Zr, V, Mg, Al, Mn, Sb, Ba, Ca, Ce, Si, and Sn; and b. the reactive group (b) is selected from the group consisting of carbazole, fluorene, imidazole with one or more functional groups selected from —OH, —NH2, —COOH, —NCO, -epoxy, -vinyl, -acrylic, -acyl, -alkyl, -halide, -amino, -ketone, -allyl, -allylic, -thiol, -isocyanate, and a mixture thereof; and the method of making and using the composition.
US08883930B2 Process for preparing graft polymers without initiator and without solvent and bitumen/polymer compositions comprising said graft polymers
A process for preparing graft polymers from a polymer is based on conjugated diene units and a graft which is a thiol derivative. The process has an absence of solvent and any radical initiator. The graft polymer can be advantageously be used as additive for a bitumen/polymer composition and in particular permits thermoreversible cross-linking.
US08883926B2 Acrylic pressure-sensitive adhesive composition for optical use and acrylic pressure-sensitive adhesive tape for optical use
An acrylic pressure-sensitive adhesive composition for optical use includes: an acrylic polymer (A) that contains, as a monomer unit, a vinyl monomer having a nitrogen atom in its backbone and that does not substantially contain a carboxyl group-containing monomer; and a (meth)acrylic polymer (B) having a weight average molecular weight of 1000 or more and less than 30000.
US08883925B2 Cyclic olefin polymer composition, use thereof, and cyclic olefin polymer
A cyclic olefin polymer composition comprising: [A] a specific cyclic olefin polymer having a softening temperature (TMA) of 120 to 300° C.; and [B] a specific cyclic olefin polymer having a glass transition temperature (Tg) of 50° C. or lower, wherein the absolute value of the difference between nD[A] and nD[B] is 0.014 or less in which nD[B] represents a refractive index of the cyclic olefin polymer [B] and nD[A] represent that of the cyclic olefin polymer [A], and the component [A] is contained in an amount of 50 to 95 parts by weight and the component [B] is contained in an amount of 5 to 50 parts by weight (provided that the total amount of the components [A] and [B] is defined as 100 parts by weight).
US08883924B2 Resin blend
Provided is a resin blend including a first resin and a second resin, the second resin having a hydrophobic functional group in a side chain and having a surface energy difference of 0.1 to 20 mN/m from the first resin at 25° C., the resin blend being capable of forming a layer separation structure. Also, provided are a pellet, a method for preparing the same, and a resin molding article having a specific layer separation structure. The resin blend may not only improve mechanical properties and surface hardness of the molding article but also shorten process time, increase productivity and reduce production cost by omitting an additional surface coating step.
US08883919B2 Reinforced polymetric materials, methods of manufacture thereof and articles comprising the same
Disclosed herein is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a low molecular weight compound that exists in the form of a second crystalline phase; wherein the second crystalline phase is dispersed within the first organic polymer phase. Disclosed herein too is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a second phase that comprises a crystalline organic polymer, wherein the crystalline organic polymer has a different molecular structure from the first organic polymer; wherein the second phase is not covalently bonded to the first organic polymer phase and wherein the second phase has an average particle size of about 1 to about 20 micrometers.
US08883918B2 Process for recycling product streams separated from a hydrocarbon-containing feed stream
The present invention relates to a process for recycling product streams that have been separated from a hydrocarbon-containing feed stream comprising olefin monomer, olefin co-monomer, hydrocarbon diluent and components such as H2, N2, O2, CO, CO2, and formaldehyde. In accordance with the present process a hydrocarbon-containing feed stream is separated into a) a first side stream comprising hydrocarbon diluent and olefin monomer; b) a second side stream which is substantially hydrogen-free and comprises hydrocarbon diluent and olefin monomer, c) a bottom stream comprising substantially olefin-free hydrocarbon diluent, and d) an overhead vapor stream comprising olefin monomer, hydrocarbon diluent and components such as formaldehyde, H2, N2, O2, CO and CO2. The present process further includes recycling said first and said second side streams in a polymerization process for preparing bimodal polyolefin.
US08883916B2 Release on demand corrosion inhibitor composition
Disclosed is cross-linking process for cross-linking polymeric chains in a coating composition. In one embodiment the process utilizes a Hantzsch dihydropyridine reaction to form reaction products including cross-linking polymeric resin chains having beta-keto ester functions using a source of aldehyde and a source of ammonia or a primary amine to form a permanent dihydropyridine bond between the beta-keto ester functions. The novel cross-linking reaction can occur at lower temperatures compared to typical cross-linking reactions and can occur in aqueous solutions that have a neutral to mildly alkaline pH of from 6 to 11. The novel cross-linking reaction provides many advantages to performing cross-linking of polymeric chains in coating resins.
US08883913B2 Resin composition, resin film, semiconductor device, and production method thereof
A resin composition which can be formed into a film for use in molding a large diameter thin film wafer is provided. The composition comprises components (A) a silicone resin containing repeating units represented by the following formulae (1-1), (1-2), and (1-3) and having a weight average molecular weight as measured by GPC in terms of polystyrene of 3,000 to 500,000, wherein r, s, and t are independently a positive integer; the silicon atom at the terminal of the units constituting the repeating units represented by the formulae (1-1), (1-2), and (1-3) is bonded to the terminal carbon atom of the X1, X2, or X3 in the same or different unit; R1 is independently a monovalent hydrocarbon group containing 1 to 8 carbon atoms; X1, X2, and X3 are independently a divalent group; (B) a thermosetting resin; and (C) a filler.
US08883912B2 Synthesis of arborescent polymers via controlled inimer-type reversible addition-fragmentation chain transfer (RAFT) polymerization
Randomly branched polymers, such as homopolymers, copolymers, block copolymers and functionalized polymers are disclosed which may be formed by polymerizing a polymerizable monomer, such as styrene with a dithioester chain transfer agent which includes a polymerizable group. The reaction may be performed in one pot. The randomly branched polymer can have high molecular weight and broad molecular weight distribution.
US08883911B2 Cobalt-based catalytic dryer for polymer coatings
This disclosure relates to catalysts for the auto-oxidative drying of polymers, in particular for polymers used in paints or inks, based on unsaturated fatty acids, mostly from vegetal origin A compound is divulged for use as a polymerisation agent in coatings, characterized in that it comprises a cobalt-bearing alkyd polymer, said polymer having a cobalt content of 0.5 to 6% by weight, a mean molecular weight of more than 3000, and comprising cobalt carboxylate sequences Several processes are presented to illustrate the synthesis of the cobalt-bearing polymer These polymers retain the catalytic effect of cobalt towards the drying of polymers, while they greatly suppress the toxicity of cobalt by being essentially insoluble in water.
US08883910B2 Resin composition for coating and molded resin product obtained therefrom
Provided is a resin composition for coating, including: 35-65 wt % of a high-molecular weight polypropylene resin (A) having a weight average molecular weight of 100,000-300,000 and an isotactic chain molar fraction, L, of 0.30-0.70; 30-60 wt % of a low-molecular weight polypropylene resin (B) having a weight average molecular weight of 10,000-50,000 and an isotactic chain molar fraction, L, of 0.30-0.70; and 0.1-5.0 wt % of a highly crystalline, low-molecular weight polypropylene resin (C) having a weight average molecular weight of 5,000-50,000 and an isotactic chain molar fraction, L, of 0.70-0.75. The polypropylene resin composition for coating is amenable to spray coating while avoiding a need for a complicated process such as discharge treatment, flame treatment or acid treatment of a polypropylene substrate, in the absence of chlorine, and is effective for forming a coating film having excellent scratch resistance and adhesive property and showing no tagging property.
US08883908B2 Methods for making reinforced thermoplastic composites using reactive fibers and/or reactive flakes
Various methods and systems of making inorganic fiber/flake reinforced composites having a thermoplastic matrix are disclosed. The methods use systems similar to those used to make inorganic fiber/flake reinforced products having a thermoset matrix, but the systems and methods are modified to use thermoplastic precursor monomer(s) followed by in situ polymerization of the monomer(s) during and/or following forming of the desired shape of the products. These methods permit the manufacture of superior inorganic fiber reinforced thermoplastic matrix composites in large and very large shapes heretofore not possible, or practical.
US08883907B2 Aqueous dispersion
Cement-free aqueous polymer dispersion comprising calcium silicate hydrate.
US08883905B2 Method of manufacturing powder coating composition
The present invention is directed to a method of manufacturing a powder coating composition containing thermosetting resin powders to which surface flake pigments have been bonded, and the method includes a first step of preparing the flake pigments having an average particle size not greater than 10 μm or an average thickness not greater than 60 nm, a second step of obtaining a dispersion by dispersing the flake pigments above in a solvent not dissolving the thermosetting resin powders, a third step of obtaining a mixture by mixing the thermosetting resin powders with the dispersion above, and a fourth step of volatilizing and removing the solvent above while the mixture above is stirred.
US08883903B2 Synthesis, capping and dispersion of nanocrystals
Preparation of semiconductor nanocrystals and their dispersions in solvents and other media is described. The nanocrystals described herein have small (1-10 nm) particle size with minimal aggregation and can be synthesized with high yield. The capping agents on the as-synthesized nanocrystals as well as nanocrystals which have undergone cap exchange reactions result in the formation of stable suspensions in polar and nonpolar solvents which may then result in the formation of high quality nanocomposite films.
US08883902B2 Aerosol dispensing systems and methods and compositions for repairing interior structure surfaces
A method of covering an anomaly in a wall substantially to match a pre-existing texture pattern surrounding the anomaly comprises the following steps. A valve is supported on a container assembly to define a main chamber. Contained material comprising wall material concentrate and propellant material is disposed within a main chamber defined by a valve and a container assembly. An actuator relative is arranged relative to the container assembly such that displacement of a button changes the valve from a closed configuration to an open configuration. A first portion of the contained material is applied to the anomaly. A second portion of the contained material is applied to the base coat. The second portion of the contained material forms a desired texture pattern on the base coat that substantially matches the pre-existing texture pattern.
US08883900B2 Electroless plating performance of laser direct structuring materials
Thermoplastic compositions that are capable of being used in a laser direct structuring process to provide enhanced plating performance and good mechanical properties. The compositions of the present invention include a thermoplastic base resin, a laser direct structuring additive and a white pigment. The compositions can be used in a variety of applications such as personal computers, notebook and portable computers, cell phone antennas and other such communications equipment, medical applications, RFID applications, and automotive applications.
US08883899B2 Flame-retarded thermoplastic compositions of high thermomechanical strength, in particular for electric cables
A flame-retarded thermoplastic composition including a graft copolymer containing polyamide blocks and composed of a polyolefin backbone and on average at least one polyamide graft, in which the grafts are attached to the backbone by the residues of an unsaturated monomer (X) having a function capable of reacting with a polyamide, the residues of the unsaturated monomer (X) are attached to the backbone by grafting or copolymerization from its double bond, wherein the composition includes: —between 60% and 70% by weight of the graft copolymer containing polyamide blocks, —between 22% and 28% by weight of poly(pentabromobenzyl acrylate), —between 4% and 8% by weight of a synergistic flame retardant chosen from antimony trioxide, derivatives of tin, of molybdenum and/or bismuth and also boron and zinc oxides, calcium borates, calcium sulphate and/or zinc stannate, between 0.5% and 5% by weight of organophilic treated clay.
US08883897B2 Functional norbornanyl ester derivatives, polymers and process for preparing same
This invention relates to the new functional norbornanyl ester derivative and/or polymer compositions which are easily obtainable by reacting the Diels-Alder adduct of appropriate dienes and dienophiles with carboxylic acids. In particular, this invention relates to a new process for making cyclic chemical raw materials suitable for production coating, ink, adhesive, plasticizer, thermoplastic or thermosetting plastic and functional polymers.
US08883892B2 Adducts with perfluoropolyether phosphate and uses thereof
The present invention relates, in one aspect, to an adduct of formula O-PF-A, in which O is an oil; PF is a perfluoropolyether phosphate (PFPE phosphate); A is at least one substance selected from: (X) a water-soluble polyhydroxylated substance and (Y) a water-insoluble inorganic substance and to topical applications thereof in particular in the cosmetic and pharmaceutical field.
US08883889B2 Pigment compositions comprising pyrrolo[3,4-c]pyrroles
The present invention relates to a process for the direct preparation of pyrrolo[3,4-c]pyrroles (DPPs) of the formula pigment compositions containing them and their use for coloring high molecular weight organic materials, such as plastics and paints. The obtained DPPs of the formula I possess a higher color strength, a higher chroma, a purer shade and a higher opacity versus corresponding commercially available DPPs.
US08883886B2 Durable thermoset binder compositions from 5-carbon reducing sugars and use as wood binders
The present invention provides thermosetting aqueous binder compositions of (i) one or more diprimary diamine, e.g. lysine, or poly(primary amine), e.g. polyethylenimine and tris(2-aminoethyl)amine, and (ii) one or more 5-carbon reducing sugar, such as xylose. The binders are at least substantially formaldehyde free and cure rapidly at temperatures sufficiently low and with sufficiently little swelling to enable one to provide wood or woody material containing articles, such as particle board, oriented strand board and bamboo boards or articles.
US08883881B2 Superabsorbent polymer with high permeability
The invention relates to absorptive, crosslinked polymers which are based on partly neutralized, monoethylenically unsaturated monomers carrying acid groups wherein the absorptive crosslinked polymer may be coated with a thermoplastic polymer, and have improved properties, in particular in respect of their capacity for transportation of liquids in the swollen state, and which has a high gel bed permeability and high centrifuge retention capacity.
US08883879B2 Pigment granules
Pigment granules including a support material which is coated with one or more flake-form effect pigments by means of an adhesion promoter. The effect pigments may be, for example, pearlescent pigments, interference pigments, metal-effect pigments, multilayered pigments having one or more transparent, semi-transparent or opaque layers, goniochromatic pigments, holographic pigments, coated BiOCL flakes, uncoated BiOCl flakes, and LCP pigments, and mixtures thereof. A process for the production of pigment granules includes mixing one or more flake-form effect pigments, a support material, at least one adhesion promoter, and optionally one or more additives simultaneously or successively with one another. The pigment granules may be used for the pigmenting of application media, in particular paints, plasters, coatings, powder coatings, plastics, and in particular as scatter and effect granules, for example for the decoration of wallcoverings. The pigment granules may additionally include one or more additives and assistants.
US08883877B2 Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides
The present invention relates to a dental material comprising, relative to the total mass of the material: (a) 1 to 95 wt.-% of at least one polymerizable N,O-functionalized acrylic acid hydroxamide, (b) 0 to 70 wt.-% diluent monomer, (c) 0 to 70 wt.-%, cross-linker monomer, (d) 0.1 to 5.0 wt.-% polymerization initiator (e) 0 to 80 wt.-% filler, (f) 0 to 70 wt.-% solvent, and (g) 0 to 70 wt.-% adhesive monomer.
US08883872B2 Polymer-bound bisacylphosphine oxides
The invention pertains to an oligomer or polymer substituted by one or more bisacylphosphine oxide moieties, characterized in that said bisacylphosphine oxide moiety is linked via the phosphorous atom, optionally via a spacer group, to the oligomer or polymer backbone; as well as to specifically functionalized bisacylphosphine oxides, suitable to prepare said polymers or oligomers.
US08883871B2 Post polymerization cure shape memory polymers
This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
US08883869B2 Impact absorbing foam
This invention relates to impact absorbing foams. These foams comprise a polymeric foam and ceramic particulates dispersing the foam. These foams have numerous uses, including, for example, as interior pads for football helmets, and the like, for reducing head injuries.
US08883865B2 Cerium-containing nanoparticles
A process for making cerium-containing oxide nanoparticles includes providing an aqueous reaction mixture containing a source of cerous ion, optionally a source of one or more metal ions (M) other than cerium, a source of hydroxide ion, at least one monoether carboxylic acid nanoparticle stabilizer wherein the molar ratio of said monoether carboxylic acid nanoparticle stabilizers to total metal ions is greater than 0.2, and an oxidant at an initial temperature in the range of about 20° C. to about 95° C. Temperature conditions are provided effective to enable oxidation of cerous ion to ceric ion, thereby forming a product dispersion of cerium-containing oxide nanoparticles, optionally containing one or more metal ions (M), Ce1-xMxO2-δ, wherein “x” has a value from about 0.0 to about 0.95. The nanoparticles may have a mean hydrodynamic diameter from about 1 nm to about 50 nm, and a geometric diameter of less than about 45 nm.
US08883862B2 Method for controlled release of parathyroid hormone from cross-linked hyaluronic acid hydrogel
A method for locally controlled release of an effective amount of PTH(1-34) by a hyaluronic acid based hydrogel that can injected intra-articularly for the treatment of osteoarthritis is provided.
US08883858B1 Small molecule xanthine oxidase inhibitors and methods of use
Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia.
US08883857B2 Small molecule xanthine oxidase inhibitors and methods of use
Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia.
US08883848B2 Enhanced microbial peracid compositions and methods of use at reduced temperatures in aseptic cleaning
The present invention relates to compositions of peracids, such as peroxycarboxylic acids, having improved antimicrobial efficacy due to ethanol solubilization of the compositions. The enhanced antimicrobial efficacy of the peracid compositions beneficially have a lower use concentration. The invention further relates to methods employing such compositions.
US08883847B2 Compositions and methods of treatment using modulators of motoneuron diseases
The invention disclosed herein describes a novel therapeutic target for motoneuron diseases (altered dynamics of microtubules in neurons); a method for measuring the state of activity of this therapeutic target in subjects with established, incipient, or potential motoneuron disease; the discovery of drug agents that modulate neuronal microtubule dynamics in living subjects with motoneuron diseases; the discovery that administration of such agents, alone or in combinations, can provide marked neuroprotective therapy for living subjects with motoneuron diseases including delay in symptoms and prolongation of survival; and the discovery that monitoring of neuronal microtubule dynamics in subjects with motoneuron diseases, in response to therapeutic interventions, allows diagnostic monitoring for optimization of therapeutic regimen and strategy for individual subjects or for drug trials.
US08883843B2 Substituted isoindoline-1,3-dione derivatives
This invention relates to novel substituted isoindoline-1,3-dione derivatives and pharmaceutically acceptable salts thereof. More specifically, the invention relates to novel substituted isoindoline-1,3-dione derivatives that are analogs of apremilast. This invention also provides compositions comprising a compound of this invention and a carrier and the use of disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering apremilast.
US08883839B2 Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
The present invention relates to tetraline and indane derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetraline and indane derivatives, and the use of such tetraline and indane derivatives for therapeutic purposes. The tetraline and indane derivatives are GlyT1 inhibitors.
US08883831B2 Compositions and methods for minimizing or reversing agonist-induced desensitization
Methods and compositions are provided for preventing or reversing loss of the therapeutic effect of a drug, where the loss is associated with the repeated administration of the drug to a patient. The method includes administering to the patient a dopamine receptor agonist or partial agonist or a drug that increases the extracellular level of dopamine by enhancing release of dopamine, decreasing the removal of dopamine from the extracellular space, enhancing the synthesis of dopamine within the brain, or decreasing metabolic degradation of dopamine; and also administering to the patient an opioid receptor antagonist in an ultra-low dose amount, wherein the ultra-low dose amount is effective to prevent or reverse loss of therapeutic effects associated with the repeated administration of the drug to the patient. The methods are useful for various treatments, including treating Parkinson's Disease, Restless Leg Syndrome, depression, schizophrenia, psychostimulant drug abuse, or attention deficit disorder.
US08883827B2 Azole derivatives as WTN pathway inhibitors
The present invention relates to new compounds of formula I, to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy. Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway. For example, these may be used in preventing and/or retarding proliferation of tumor cells, for example carcinomas such as colon carcinomas.
US08883824B2 3-(4-aminophenyl)-2-furancarboxylic acid derivative and pharmaceutically acceptable salt thereof
Disclosed is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 is 1: a C3-8 cycloalkyl C1-4 alkyl group, 2: a C7-14 aralkyl group, in which the aryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of: (a) halogen, (b) C1-4 alkyl, which is optionally substituted with 1 to 3 fluorine atoms, (c) C1-4 alkoxy, which is optionally substituted with 1 to 3 fluorine atoms, and (d) C1-4 alkylcarbonyl, which is optionally substituted with C1-4 alkoxy, 3: a five-to ten-membered heteroaryl-C1-4 alkyl group, in which the heteroaryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of: (a) halogen, and (b) C1-4 alkyl, or 4: a C6-10 aryl C2-6 alkenyl group; and R2 is a cyano group or a nitro group.
US08883821B2 Substituted pyrazolo[3,4-b]pyridines as medicaments
The present invention relates to a compound of following formula (I): or a pharmaceutically acceptable salt or solvate of same, a tautomer of same, or a stereoisomer or mixture of stereoisomers of same in any proportions, such as a mixture of enantiomers, notably a racemic mixture; as well as to the use of same as a drug, notably intended for the treatment of cancer, inflammation and neurodegenerative diseases such as Alzheimer's disease; to the use of same as a kinase inhibitor; to the pharmaceutical compositions comprising same; and to methods for the preparation of same.
US08883820B2 Triazole derivatives as kinase inhibitors
The invention relates to compounds of formula (I); wherein X and R1 to R5 have the meaning as cited in the description and the claims. Said compounds are useful as protein kinase inhibitors, especially inhibitors of Itk or PI3K, for the treatment or prophylaxis of immunological, inflammatory or allergic disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the production of and use as medicaments.
US08883819B2 Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
Bicyclic heterocyclic derivatives of formula I useful in inhibiting PDGF receptor mediated biological activity. wherein A is and R1, R1a, R2, R3, R4, R5, R6 and X are as defined herein.
US08883816B2 Fused and spirocycle compounds and the use thereof
The invention relates to fused and spirocycle compounds of Formula I: or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R1, R2, Q1-Q3, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
US08883813B2 Treatment of CNS disorders associated with mutations in genes encoding lysosomal enzymes
Described is a method for treating an individual having a neurological disorder with an associated mutation or mutations in a gene encoding a lysosomal enzyme. Specifically, the individual is administered a specific pharmacological chaperone for the lysosomal enzyme which increases trafficking of the protein from the ER to the lysosome in neural cells, with or without concomitantly increasing enzyme activity in neural cells. Restoration of trafficking relieves cell stress and other toxicities associated with accumulation of mutant proteins. Restoration of enzyme activity relieves substrate accumulation and pathologies associated with lipid accumulation. In a specific embodiment, the neurological disorder is Parkinson's disease or parkinsonism which is associated with mutations in glucocerebrosidase.
US08883799B2 Tricyclic PI3K inhibitor compounds and methods of use
Tricyclic PI3k inhibitor compounds of Formula I with anti-cancer activity, anti-inflammatory activity, or immunoregulatory properties, and more specifically with PI3 kinase modulating or inhibitory activity are described. Methods are described for using the tricyclic PI3K inhibitor compounds of Formula I for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, organisms, or associated pathological conditions. Formula I compounds include stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof. The dashed lines indicate an optional double bond, and at least one dashed line is a double bond. The substituents are as described.
US08883794B2 Pharmaceutical composition
A preparation for oral administration comprising: a pregelatinized starch comprising N-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]-(2R,3R)-2,3-tetramethylene-butyl]-(1′R,2′S,3′R,4′S)-2,3-bicyclo[2,2,1]-heptanedicarboxylmide hydrochloride (lurasidone) represented by the formula (1) as an active ingredient; a water-soluble excipient; and a water-soluble polymeric binder, the preparation exhibiting an invariant level of elution behavior even when the content of its active ingredient is varied.
US08883782B2 Spiro-tetracyclic ring compounds as beta-secretase modulators and methods of use
The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and other related conditions. In one embodiment, the compounds have a general Formula I wherein A1, A2, A3, A4, A5, A6, R2, R7, X and Y of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula I, intermediates and processes useful for the preparation of compounds of Formula I.
US08883779B2 Oxazine derivatives and a pharmaceutical composition for inhibiting BACE1 containing them
The present invention provides a compound of formula (I): wherein —X═ is —CR7═ or —N═, ring B is a substituted or unsubstituted carbocycle or a substituted or unsubstituted heterocycle, R1 is substituted or unsubstituted alkyl or the like, R2 a and R2 b are each independently hydrogen, substituted or unsubstituted alkyl or the like, R3 and R4 are each independently hydrogen, halogen, substituted or unsubstituted alkyl or the like, R5 is hydrogen, substituted or unsubstituted alkyl or the like, each R6 is independently halogen, hydroxy, substituted or unsubstituted alkyl or the like, R7 is hydrogen, halogen, hydroxy, substituted or unsubstituted alkyl or the like, p is an integer of 0 to 3, or a pharmaceutically acceptable salt thereof which has an effect of inhibiting amyloid β production, especially an effect of inhibiting BACE1, and which is useful as a therapeutic or prophylactic agent for diseases induced by production, secretion and/or deposition of amyloid β proteins.
US08883770B2 Synthetic bile acid compositions and methods
Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
US08883769B2 Methods for the treatment of fibromyalgia and chronic fatigue syndrome
The invention relates to methods for the treatment of fibromyalgia and chronic fatigue syndrome by administration of a transdermally applied androgen composition. The treatment is both safe and effective for treating fibromyalgia-related pain and fatigue, as well as chronic fatigue syndrome.
US08883768B2 Fluocinolone implants to protect against undesirable bone and cartilage destruction
Effective treatments for protecting against undesirable macrophage activity are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce or prevent macrophage activity. In various embodiments, fluocinolone formulations may be provided within biodegradable polymers to prevent transplant rejection for at least thirty days. In some embodiments, the relief can be for at least sixty days, or up to ninety days.
US08883767B2 Low ether compositions and delivery apparatus
A low ether gel composition for application to skin comprising a keratolytic agent, in particular salicylic acid, and comprising a nitrocellulose and one or more volatile ingredients, which forms a film on contact with skin adequate to form a protective barrier for the keratolytic agent for a period of time necessary to provide treatment to the skin; methods of treating using such compositions, and dispensers containing such compositions.
US08883766B2 Ion channel modulators and methods of use
In general, the invention relates to compounds useful as ion channel modulators. It has now been found that compounds of this invention, and pharmaceutically acceptable compositions thereof, are useful as inhibitors of voltage-gated sodium channels.
US08883764B1 Formylpyrrole-based heterocycles for nucleic acid attachment to supports
A compound has Formula I: A, B, C, D, W, X, Y, and Z are independently selected from hydrogen, optionally substituted C1-C6 alkyl, optionally substituted C1-C6 alkoxy, aryl, aldehyde, protected aldehyde, CH, N, O, S, null, and bond; Q is selected from aldehyde, protected aldehyde, and null, at least one of A, B, C, D, W, X, Y, Z, or Q is an aldehyde or protected aldehyde; the bonds between each of A-B, B-C, C-D, W-X, X-Y, and Y-Z are selected from single bond, double bond, triple bond, and no bond; L is a linker selected from a C1-C12 alkyl, aralkyl, and aryl, any of which is optionally substituted; one or more methylene unit (CH2) of the C1-C12 alkyl is optionally replaced by any combination of oxygen, carbonyl(C═O), and NH; and R1 and R2 are independently selected from —NR3R4, halogen, C1-C8 alkoxy, aralkoxy, alkenyloxy, alkynyloxy, and OCH2CH2CN; R3 and R4 are independently a C1-C4, straight chain or branched alkyl group.
US08883761B2 Use of lipid conjugates in the treatment of diseases associated with vasculature
This invention provides for the use of compounds represented by the structure of the general formula (I): wherein R1 is a linear, saturated, mono-unsaturated, or poly-unsaturated, alkyl chain ranging in length from 2 to 30 carbon atoms; R2 is a linear, saturated, mono-unsaturated, or poly-unsaturated, alkyl chain ranging in length from 2 to 30 carbon atoms; Y is either nothing or a spacer group ranging in length from 2 to 30 atoms; X is either a physiologically acceptable monomer, dimer, oligomer or a physiologically acceptable polymer, wherein X is a glycosaminoglycan; and n is a number from 2 to 1,000; wherein if Y is nothing the phosphatidylethanolamine is directly linked to X via an amide bond and if Y is a spacer, said spacer is directly linked to X via an amide or an esteric bond and to said phosphatidylethanolamine via an amide bond, thereby inhibiting the development of a psoriatic plaque or reducing plaque size in a subject.
US08883754B2 Method for inhibiting angiogenesis
The present invention relates to a method for inhibiting angiogenesis using a peroxiredoxin II (Prx II) inhibitor, and a method for preparing angiogenesis-inhibiting medicines using Prx II inhibitor. According to the present invention, the inhibitor of Prx II gene expression or Prx II protein activity increases oxidative inactivation of VEGF receptor tyrosine kinase (RTK) to reduce VEGF signaling, thereby screening a novel angiogenesis inhibitor. Therefore, the method of the present invention can be used for the prevention or treatment of various diseases, ailments, and conditions related to angiogenesis.
US08883753B2 Expression of apoAI and variants thereof using spliceosome mediated RNA trans-splicing
Methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated RNA trans-splicing that result in expression of a apoAI protein, an apoAI variant, the preferred embodiment referred to herein as the apoAI Milano variant, a pre-pro-apoAI or an analog of apoAI. The methods and compositions include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and mediate a trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (chimeric RNA) capable of encoding apoAI, the apoAI Milano variant, or an analog of apoAI. The expression of this apoAI protein results in protection against vascular disorders resulting from plaque build up, i.e., atherosclerosis, strokes and heart attacks.
US08883747B1 Topical antifungal compositions and methods of use thereof
Described herein are compositions and methods that treat fungal infections of the skin, reduce the severity and duration of symptoms of fungal infections of the skin, and prevent recurrence of fungal infections. The topical compositions described herein are creamy pastes composed of an admixture of an imidazole antifungal and nystatin. The topical compositions can also include optional fillers. The compositions and methods described herein minimize fungal resistance and maximize the number of targeted fungal strains. Additionally, the compounds and methods do not suppress the body's immune system either locally or systemically, thus allowing for a faster restoration of normal skin flora. The compositions and methods described herein are particularly suitable for use in infants and children as well as in immunocompromised individuals, diabetics, and the obese.
US08883741B2 Stimulator of genital, sexual and reproductive function
The invention relates to a novel agent having an influence on the genital, sexual and reproductive function of mammals and human beings. More specifically, the invention relates to the use of a heptapeptide of the general formula (I) Thr-Lys-Pro-Arg-Pro-Gly-Pro (SEQ ID NO: 1) as a stimulator of the genital, sexual and reproductive function of mammals and human beings. The invention widens the range of agents available for stimulating the genital, sexual and reproductive function of mammals and human beings.
US08883739B2 Osteocalcin as a treatment for male reproductive disorders
Methods and compositions for treating, preventing, or diagnosing disorders related to reproduction in male mammals, preferably humans, are provided. The methods generally involve modulation of the OST-PTP signaling pathway or the PTP-IB signaling pathway involving gamma-carboxylase and osteocalcin. Disorders amenable to treatment by the methods include, but are not limited to, male infertility, low sperm count, impaired sperm motility, impaired sperm viability, low testosterone levels, reduced libido, erectile dysfunction, underdevelopment of testes, and excess apoptosis in testes.
US08883733B2 Cell cultivation in chitosan alginate hydrogel beads
The present invention relates to a method of producing a hydrogel matrix comprising cartilage-forming cells wherein alginate, chitosan and cartilage-forming cells are mixed and subsequently polymerized into beads.
US08883731B2 Agent for reducing risk in onset of disease ascribable to non-dipper circadian rhythm of blood pressure
An agent for reducing risk in onset of diseases ascribable to non-dipping circadian profile of blood pressure is provided. This agent is capable of effectively lowering SBP from night to early morning in individuals with non-dipping circadian profile of blood pressure, in particular, normal individuals with normal SBP and DBP among them, and is thus capable of reducing risk in onset, particularly likely in the morning, of diseases caused by circadian variation of blood pressure. The agent is intended for administration to such subjects, and contains a hydrolysate or a concentrate thereof, containing Val-Pro-Pro and Ile-Pro-Pro and obtained by hydrolysis of animal milk protein.
US08883728B2 Intranasal administration of active agents to the central nervous system
Pharmaceutical compositions and methods for delivering a polypeptide to the central nervous system of a mammal via intranasal administration are provided. The polypeptide can be a catalytically active protein or an antibody, antibody fragment or antibody fragment fusion protein. The polypeptides are formulated with one or more specific agents.
US08883726B2 Fibroblast growth factor 21 variants
This present invention relates to pharmacologically potent and/or stable variants of human fibroblast growth factor 21 (FGF21), pharmaceutical compositions comprising FGF21 variants, and methods for treating type 2 diabetes, obesity, dyslipidemia, or metabolic syndrome, or any combination thereof, using such variants.
US08883725B2 Compositions and methods for modulating skin pigmentation
The present invention relates to compositions and methods useful in studying or modulating melanin pigmentation in the skin. Particularly, the invention relates to compositions comprising a substance capable of modulating the activity or expression of ALK6 (SEQ ID 2) or Cdc42 which in turn are capable of modulation of the transfer of melanin from melanocytes to keratinocytes and potentially from keratinocytes to keratinocytes. The invention also relates to assays for identifying such compositions, and methods of modulating skin pigmentation.
US08883723B2 Conjugate of insulin and vitamin B12 for oral delivery
Compositions containing a therapeutic peptide covalently linked to Vitamin B12 at the 5′-hydroxyl group of the ribose moiety of α-ligand are described. The length of the linkage is optimized so that the biological activity of both the Vitamin B12 and the therapeutic peptide is maintained. Therapeutic peptide includes insulin, PYY, NPY and GLP-1. Attachment to Vitamin B12 provides uptake of the therapeutic peptide from the digestive tract and longer residence time.
US08883720B2 Template-fixed beta-hairpin peptidomimetics with CXCR4 antagonizing activity
Template-fixed peptidomimetics formula (Ia) formula (Ib) wherein Z is a template-fixed chain of 14 α-amino and/or α-hydroxy acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid), are Pro, Gly, a glycolic acid residue or of certain types which, as the remaining symbols in the above formulae, are defined in the description and the claims, and salts thereof, have CXCR4 antagonizing properties and can be used for preventing HIV infections in non-infected individuals or for slowing and halting viral progression in infected patients; or where cancer is mediated or resulting from CXCR4 receptor activity; or where immunological diseases are mediated or resulting from CXCR4 receptor activity; or for treating immuno suppression; or during apheresis collections of peripheral blood stem cells and/or as agents to induce mobilization of stem cells to regulate tissue repair. These depsipeptides can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
US08883716B2 Method for treating damaged tissue of the CNS
Devices and methods for treating diseases associated with loss of neuronal function are described. The methods are designed to promote proliferation, differentiation, migration, or integration of endogenous progenitor stem cells of the central nervous system (CNS). A therapy, such as an electrical signal or a stem cell enhancing agent, or a combination of therapies, is applied to a CNS region containing endogenous stem cells or a CNS region where the endogenous stem cells are predicted to migrate and eventually reside, or a combination thereof.
US08883711B2 Cleaning composition with improved stain removal
The invention relates to a cleaning composition with improved stain removal. The alkaline composition contains a hydrolysable dispersing polymer which is selected from carboxylated fructans and one or more biodegradable aminocarboxylate chelating agents.
US08883710B2 Compositions and methods incorporating photocatalysts
The present invention includes compositions comprising an active material having groups capable of covalent attachment to a substrate in the presence of an acid or a base, a photocatalyst capable of generating an acid or a base upon exposure to light, and a vehicle. Also included herein is a method for treating a substrate with these compositions. The method includes the steps of applying at least one active material having functional groups to the substrate, applying a photocatalyst to the substrate, and exposing the photocatalyst and the at least one active material to light for forming covalent attachments between the functional groups and constituent groups on the substrate. The compositions and methods described herein are useful in consumer care and personal care product applications.
US08883696B2 Sliding mechanism and friction reduction method for the same
The purpose of the present invention is to provide: a sliding mechanism having a lubricating film formed on the sliding surface thereof, and capable of exhibiting friction-reducing performance; and a friction reduction method for the same. To that end, the present invention entails coating the sliding surface with chromium nitride, adding a molybdenum dithiocarbamate with molybdenum in the amount of 600-1000 ppm to diesel engine oil, setting the arithmetic mean roughness of the sliding member to 2-60 nm, and upon converting the Sommerfeld number viscosity to Pa·s, the speed to s−1, and the load to mean Hertzian stress (Pa), then the lubrication conditions for use are within the range of 2.12365×10−20 to 5.94509×10−19.
US08883695B2 Particulate materials coated with a relative permeability modifier and methods for treating subterranean formations using treatment fluids containing the same
Reduction of the water permeability within a subterranean formation, particularly within a proppant pack or a gravel pack, can be achieved through the use of a relative permeability modifier (RPM) coated on a particulate material. Methods for reducing the water permeability include providing RPM-coated particulates that contain a RPM coating on the particulates, and placing a treatment fluid containing a base fluid and the RPM-coated particulates in at least a portion of a subterranean formation. The treatment fluid can also contain a companion polymer that serves to further reduce the water permeability compared to that achievable when using the RPM alone.
US08883694B2 Polysaccharide slurries with environmentally friendly activator solvents
A stable polysaccharide particle suspension composition comprising: a carrier; an activator solvent comprising a) at least one dibasic methyl or ethyl ester; b) at least one compound of the formula R3OOC-A-CONR4R5 (IIa), wherein R3 represents a C1-C36 alkyl group; wherein R4 and R5 individually represents a C1-C36 alkyl group, wherein R4 and R5 can optionally together form a ring; and wherein A is a linear or branched divalent C2-C6 alkyl group; or c) a combination a) and b); an organo clay compound; and optionally, a surfactant; the composition being stable and capable of suspending polysaccharide particles. Slurries of polysaccharide particles in such suspension composition and methods of making the compositions and the slurries.
US08883689B2 Stabilized herbicidal compositions
A herbicide composition includes a fenoxaprop ester and a weak acid buffer system. The buffer system maintains the herbicidal composition at a pH in the range of 4 to 8. In one non-limiting embodiment, the fenoxaprop ester is fenoxaprop ethyl. The buffer system can include an amine-containing material, such as a tertiary amine. The herbicide composition can include other herbicides, such as weak acid herbicides, for example pyrasulfotole, bromoxynil, and/or bromoxynil esters and can include one or more safeners.
US08883688B2 Arylalkyl esters of 4-amino-6-(substituted phenyl)-picolinates and 6-amino-2-(substituted phenyl)-pyrimidinecarboxylates and their use as selective herbicides for crops
Arylalkyl esters of 4-aminopicolinic acids and 6-amino-4-pyrimidinecarboxylates are herbicides for control of weeds especially those species common to rice and wheat cropping systems and in pasture management programs.
US08883680B2 Herbicide combinations with particular sulphonyl ureas
Herbicide combinations comprising components (A) and (B) show improved herbicidal effects: (A) one or more herbicides from the group of the compounds of the formula (I) and their salts, and (B) one or more herbicides from the group of the compounds of the formula (II) and their salts and esters, in which R1=is fluorine or chlorine, R2=is H or chlorine, R3=is H or NH2, and R4=is COOH, OCH2COOH, OCH2COOCH(CH3)CH2O(CH2)3CH3 or OCH2COOCH(CH3)(CH2)5CH3, where at least one of the radicals R2 and R3 is different from H.
US08883677B2 Soil improver and use thereof
The invention relates to a soil improver which is suitable especially for increasing the water absorption and/or water storage of soils, said soil improver comprising a water-swellable matrix material based on at least one organic polymer, inorganic solid particle having been added to said matrix material, and said organic polymer of said water-swellable matrix material comprising carbohydrate-based structural units, especially carbohydrate-based functional groups.
US08883664B2 Optical glass, press-molding glass material, and optical element and method of the same
An aspect of the present invention relates to optical glass, which is oxide glass comprising various cationic components in prescribed amounts without Pb, with a refractive index nd of 1.750 to 1.850, an Abbé number νd of 29.0 to 40.0, and a glass transition temperature of less than 630° C.
US08883662B2 Leather-like sheet bearing grain finish and process for producing the same
A (semi)grain-finished leather-like sheet composed of an entangled nonwoven fabric of three-dimensionally entangled fiber bundles containing microfine long fibers and an elastic polymer contained in the entangled nonwoven fabric. When dividing the (semi)grain-finished leather-like sheet to five layers with equal thickness, i.e., surface layer, substrate layer 1, substrate layer 2, substrate layer 3 and back layer in this order along the thickness direction, part of the microfine long fibers forming the surface layer and/or the back layer are fuse-bonded to each other and the microfine long fibers forming the intermediate layer are not fuse-bonded. With such a fuse-bonding state of the microfine long fibers, the (semi)grain-finished leather-like sheet combines a low compression resistance and a dense feel each comparable to natural leathers, has a sufficient practical strength, and are excellent in properties which are required according to its use.
US08883658B2 Translucent composite
The invention relates to a translucent composite and a method for producing the translucent composite. The invention includes a plurality of composite materials laid on top of one another and bonded to each other in the region of the bonding surfaces, and includes at least one light transmitting textile, which extends from one side of the composite to the other opposite side of the composite, and is embedded between the bonding surfaces with the composites firmly bonded together.
US08883657B2 Latex coated high performance polyethylene fabrics
Provided among other things is a fabric comprising: a HPPE base fabric; coated thereon a primer polymer; and coated on the primer polymer a liquid-resistant polymer layer. The primer polymer can be a polyurethane. The base fabric can comprise an adhesion promoter that can be a plasticizer. The adhesion promoter can be a sulfonic acid plasticizer. The adhesion promoter can contain an active hydrogen, carboxy, carboxyloxy or acid group. The fabric can comprise, coated on the liquid-resistant polymer layer, an additional polymer layer. The additional polymer layer can comprise carnauba wax in an amount from about 1 to 3% Phr. The liquid-resistant polymer layer can be a NBR layer. In certain embodiments, the fabric shows no delamination of the liquid-resistant polymer layer after an adherence test. The primer layer can be a polyurethane layer. These features can be present in any combination.
US08883652B2 Silicon etching liquid and etching method
A silicon etching liquid characterized by anisotropically dissolving monocrystalline silicon therein by using an aqueous solution containing a quaternary ammonium hydroxide and an aminoguanidine salt and an etching method of silicon using the instant etching liquid are an etching liquid and an etching method enabling one to perform processing at a high etching rate in etching processing of silicon, particularly in etching processing of silicon in a manufacturing process of MEMS parts or semiconductor devices.
US08883650B2 Method of removing oxides
The present invention provides a method of removing oxides. First, a substrate having the oxides is loaded into a reaction chamber, which includes a susceptor setting in the bottom portion of the chamber, a shower head setting above the susceptor, and a heater setting above the susceptor. Subsequently, an etching process is performed. A first thermal treatment process is then carried out. Finally, a second thermal treatment process is carried out, and a reaction temperature of the second thermal treatment process is higher than a reaction temperature of the first thermal treatment process.
US08883649B2 Sidewall image transfer process
An improved method of performing sidewall spacer imager transfer is presented. The method includes forming a set of sidewall spacers next to a plurality of mandrels, the set of sidewall spacers being directly on top of a hard-mask layer; transferring image of at least a portion of the set of sidewall spacers to the hard-mask layer to form a device pattern; and transferring the device pattern from the hard-mask layer to a substrate underneath the hard-mask layer.
US08883648B1 Manufacturing method of semiconductor structure
A manufacturing method of a semiconductor structure is disclosed. The manufacturing method includes the following steps: providing an underlying layer; forming a tri-layered photoresist on the underlying layer, which comprises forming a bottom photoresist layer on the underlying layer, forming a silicon-containing material layer on the bottom photoresist layer, and forming a patterned photoresist layer on the silicon-containing material layer; performing an atomic layer deposition (ALD) process for forming a thin layer on the tri-layered photoresist; and performing an etching process for forming a via hole, which comprises etching the silicon-containing material layer according to the thin layer on the tri-layered photoresist.
US08883647B2 Method of manufacturing of trench substrate
Disclosed herein are a trench substrate and a method of manufacturing the same. The trench substrate includes a base substrate, an insulating layer formed on one side or both sides of the base substrate and including trenches formed in a circuit region and a dummy region positioned at a peripheral edge of the trench substrate, and a circuit layer formed in the trenches of the circuit region through a plating process and including a circuit pattern and vias. Thanks to formation of the trenches in the dummy region and the cutting region, deviation in thickness of a plating layer formed on the insulating layer in a plating process is improved upon.
US08883645B2 Nanopillar field-effect and junction transistors
Methods for fabrication of nanopillar field effect transistors are described. These transistors can have high height-to-width aspect ratios and be CMOS compatible. Silicon nitride may be used as a masking material. These transistors have a variety of applications, for example they can be used for molecular sensing if the nanopillar has a functionalized layer contacted to the gate electrode. The functional layer can bind molecules, causing an electrical signal in the transistor.
US08883644B2 Single spacer process for multiplying pitch by a factor greater than two and related intermediate IC structures
Single spacer processes for multiplying pitch by a factor greater than two are provided. In one embodiment, n, where n≧2, tiers of stacked mandrels are formed over a substrate, each of the n tiers comprising a plurality of mandrels substantially parallel to one another. Mandrels at tier n are over and parallel to mandrels at tier n−1, and the distance between adjoining mandrels at tier n is greater than the distance between adjoining mandrels at tier n−1. Spacers are simultaneously formed on sidewalls of the mandrels. Exposed portions of the mandrels are etched away and a pattern of lines defined by the spacers is transferred to the substrate.
US08883642B2 Method of manufacturing semiconductor device and semiconductor manufacturing apparatus
In one embodiment, a method of manufacturing a semiconductor device includes forming a concave portion on a surface of a substrate to be processed. The method further includes forming a coating film on the substrate to embed the coating film in the concave portion. The method further includes performing a first heat treatment in an atmosphere including an oxidant which contains polar molecules. The method further includes performing a second heat treatment after the first heat treatment by irradiating the coating film with a microwave after or while exposing the coating film to a liquid or a gas containing polar molecules.
US08883640B1 Sequential station tool for wet processing of semiconductor wafers
Methods and apparatus are provided for processing semiconductor wafers sequentially. Sequential processes employ multi-station processing modules, where particular encompassing wafer processes are divided into sub-processes, each optimized for increasing wafer to wafer uniformity, result quality, and overall wafer throughput. In one example, a copper electroplating module includes separate stations for wetting, initiation, seed layer repair, fill, overburden, reclaim, and rinse.
US08883634B2 Package interconnects
A method for forming a device is disclosed. A substrate having first and second major surfaces is provided. A stress buffer is formed in the substrate. A through silicon via (TSV) contact is formed between the stress buffer. The stress buffer has a depth less than a depth of the TSV contact. The stress buffer alleviates stress created by the difference in coefficient thermal expansion (CTE) between the TSV contact and the substrate.
US08883633B2 Molecular self-assembly in substrate processing
Methods for sealing a porous dielectric are presented including: receiving a substrate, the substrate including the porous dielectric; exposing the substrate to an organosilane, where the organosilane includes a hydrolysable group for facilitating attachment with the porous dielectric, and where the organosilane does not include an alkyl group; and forming a layer as a result of the exposing to seal the porous dielectric. In some embodiments, methods are presented where the organosilane includes: alkynyl groups, aryl groups, flouroalkyl groups, heteroarlyl groups, alcohol groups, thiol groups, amine groups, thiocarbamate groups, ester groups, ether groups, sulfide groups, and nitrile groups. In some embodiments, method further include: removing contamination from the porous dielectric and a conductive region of the substrate prior to the exposing; and removing contamination from the conductive region after the forming.
US08883632B2 Manufacturing method and manufacturing apparatus of device
A manufacturing method of a device including: a first process in which a barrier film is formed on a substrate with a concave portion provided on one surface thereof so as to cover an inner wall surface of the concave portion; a second process in which a conductive film is formed so as to cover the barrier film; and a third process in which the conductive film is melted by a reflow method, wherein the method includes a process α between the second process and the third process, in which the substrate with the barrier film and the conductive film laminated thereon in this order is exposed to an atmosphere under a pressure A for a time period B, and wherein in the process α, control is carried out such that a product of the pressure A and the time period B is not greater than 6×10−4 [Pa·s].
US08883630B2 Method of forming contact holes
A method of forming contact holes includes: forming a first conductive layer and a second conductive layer; forming an insulating layer on the first conductive layer and the second conductive layer; forming a photoresist pattern which exposes first and second etch surfaces of a top surface of the insulating layer; performing a first etching process on the insulating layer at a first etching rate; and performing a second etching process on the insulating layer at a second etching rate which is higher than the first etching rate, after a top surface of the first conductive layer is exposed through the insulating layer. The first etch surface is on the first conductive layer, the second etch surface is on the second conductive layer, and a distance between the second etch surface and the second conductive layer is greater than a distance between the first etch surface and the first conductive layer.
US08883627B2 Method for chip packaging
Provided is a method for chip packaging, including the steps of: providing a semi-packaged wafer which has a cutting trail and a metal bonding pad of the chip; forming a first protective layer on the cutting trail; forming on the metal bonding pad a sub-ball metal electrode; forming a solder ball on the sub-ball metal electrode; dicing the wafer along the cutting trail. The first protective layer according to the present invention can prevent the metal in the cutting trail from being separated by electroplating, and protect the lateral sides of a discrete chip after cutting. The process flow thereof is simple, and enhances the efficiency of the packaging as well as its yield.
US08883624B1 Integration of a memory transistor into high-K, metal gate CMOS process flow
Memory cells including embedded SONOS based non-volatile memory (NVM) and MOS transistors and methods of forming the same are described. Generally, the method includes: forming a gate stack of a NVM transistor in a NVM region of a substrate including the NVM region and a plurality of MOS regions; and depositing a high-k dielectric material over the gate stack of the NVM transistor and the plurality of MOS regions to concurrently form a blocking dielectric comprising the high-k dielectric material in the gate stack of the NVM transistor and high-k gate dielectrics in the plurality of MOS regions. In one embodiment, a first metal layer is deposited over the high-k dielectric material and patterned to concurrently form a metal gate over the gate stack of the NVM transistor, and a metal gate of a field effect transistor in one of the MOS regions.
US08883623B2 Facilitating gate height uniformity and inter-layer dielectric protection
Methods of facilitating replacement gate processing and semiconductor devices formed from the methods are provided. The methods include, for instance, providing a plurality of sacrificial gate electrodes with sidewall spacers, the sacrificial gate electrodes with sidewall spacers being separated by, at least in part, a first dielectric material, wherein the first dielectric material is recessed below upper surfaces of the sacrificial gate electrodes, and the upper surfaces of the sacrificial gate electrodes are exposed and coplanar; conformally depositing a protective film over the sacrificial gate electrodes, the sidewall spacers, and the first dielectric material; providing a second dielectric material over the protective film, and planarizing the second dielectric material, stopping on and exposing the protective film over the sacrificial gate electrodes; and opening the protective film over the sacrificial gate electrodes to facilitate performing a replacement gate process.
US08883621B2 Semiconductor structure and method of fabricating MOS device
Provided is a semiconductor structure including a gate structure, a first spacer, and a second spacer. The gate structure is formed on a substrate and includes a gate material layer, a first hard mask layer disposed on the gate material layer, and a second hard mask layer disposed on the first hard mask layer. The first spacer is disposed on sidewalls of the gate structure. The second spacer is disposed adjacent to the first spacer. The etch rate of the first hard mask layer, the etch rate of the first spacer, and the etch rate of the second spacer are substantially the same and significantly smaller than the etch rate of the second hard mask layer in a rinsing solution.
US08883619B2 Method for manufacturing semiconductor device
A method for manufacturing a semiconductor device includes the steps of: preparing a substrate made of silicon carbide; forming, on one main surface of the substrate, a detection film having a light transmittance different from that of silicon carbide; confirming presence of the substrate by applying light to the detection film; and forming an active region in the substrate whose presence has been confirmed.
US08883616B2 Germanium on insulator apparatus
In an implementation, a Germanium on insulator apparatus is fabricated by forming a patterned masking layer on a Silicon on insulator (SOI) layer that leaves a portion of the SOI layer exposed, implanting Germanium onto the exposed portion of the SOI layer to form a Silicon-Germanium island, depositing amorphous Germanium over the Silicon-Germanium island and the patterned masking layer, removing the patterned masking layer and the amorphous Germanium that was deposited onto the patterned masking layer to produce a Silicon-Germanium composite stripe, and annealing the Silicon-Germanium composite stripe to crystallize the amorphous Germanium in the Silicon-Germanium composite stripe.
US08883614B1 Wafer dicing with wide kerf by laser scribing and plasma etching hybrid approach
Methods of dicing semiconductor wafers, each wafer having a plurality of integrated circuits, are described. In an example, approaches for wafer dicing with wide kerf by using a laser scribing and plasma etching hybrid approach are described. For example, a method of dicing a semiconductor wafer including a plurality of integrated circuits separated by dicing streets involves forming a mask above the semiconductor wafer, the mask having a layer covering and protecting the integrated circuits. The method also involves patterning the mask with a laser scribing process to provide a patterned mask having a pair of parallel gaps for each dicing street, exposing regions of the semiconductor wafer between the integrated circuits. Each gap of each pair of parallel gaps is separated by a distance. The method also involves etching the semiconductor wafer through the gaps in the patterned mask to singulate the integrated circuits.
US08883609B2 Method for manufacturing a semiconductor structure
According to an embodiment, a method for manufacturing a semiconductor structure includes providing a first monocrystalline semiconductor portion having a first lattice constant in a reference direction and forming a second monocrystalline semiconductor portion having a second lattice constant in the reference direction, which is different to the first lattice constant, on the first monocrystalline semiconductor portion.
US08883603B1 Silver deposition method for a non-volatile memory device
A method for forming a silver structure for a non-volatile memory device includes providing a silver layer material upon a underlying substrate, forming a diffusion barrier material overlying the silver layer material, forming a dielectric hard mask material overlying the diffusion barrier material, subjecting the dielectric hard mask material to a patterning and etching process to form a hard mask and to expose a portion of the diffusion barrier material, subjecting the portion of the diffusion barrier material to an etching process using one or more chlorine bearing species as an etchant material, wherein one or more chloride contaminant species is formed overlying at least a portion of the silver layer material, and reacting the one or more chloride contaminant species with a solution comprising an ammonia species to form a water soluble species, wherein the ammonia species is free from an oxidizing species.
US08883602B2 Memory devices having electrodes comprising nanowires, systems including same and methods of forming same
Memory devices having memory cells comprising variable resistance material include an electrode comprising a single nanowire. Various methods may be used to form such memory devices, and such methods may comprise establishing contact between one end of a single nanowire and a volume of variable resistance material in a memory cell. Electronic systems include such memory devices.
US08883595B2 Process for forming a short channel trench MOSFET and device formed thereby
A process for forming a short channel trench MOSFET. The process includes forming a first implant at the bottom of a trench that is formed in the body of the trench MOSFET and forming a second or angled implant that is tilted in its orientation and directed perpendicular to the trench that is formed in the body of the trench MOSFET. The second implant is adjusted so that it does not reach the bottom of the trench. In one embodiment the angled implant is n-type material.
US08883592B2 Non-volatile memory cell having a high K dielectric and metal gate
A non-volatile memory including a substrate of a first conductivity type with first and second spaced apart regions formed therein of a second conductivity type with a channel region therebetween. A polysilicon metal gate word line is positioned over a first portion of the channel region and spaced apart therefrom by a high K dielectric layer. The metal portion of the word line is immediately adjacent to the high K dielectric layer. A polysilicon floating gate is immediately adjacent to and spaced apart from the word line, and positioned over and insulated from another portion of the channel region. A polysilicon coupling gate is positioned over and insulated from the floating gate. A polysilicon erase gate is positioned on another side of and insulated from the floating gate, positioned over and insulated from the second region, and immediately adjacent to but spaced apart from another side of the coupling gate.
US08883590B2 Phase change memory apparatus and fabrication method thereof
A phase change memory apparatus is provided that includes a first electrode that is longer than it is wide, the first electrode having a trench formed on an active region of a semiconductor substrate, a second electrode formed in a bottom portion of the trench, and a bottom electrode contact formed on the second electrode.
US08883586B2 Mol insitu Pt rework sequence
The amount of Pt residues remaining after forming Pt-containing NiSi is reduced by performing an O2 flash while shaping gate spacers, and then cleaning and applying a second application of Aqua Regia. Embodiments include sputter depositing a layer of Ni/Pt on a semiconductor substrate, annealing the Ni/Pt layer, wet stripping unreacted Ni, annealing the Ni stripped Ni/Pt layer, stripping unreacted Pt from the annealed Ni/Pt layer, e.g., with Aqua Regia, treating the Pt stripped Ni/Pt layer with an oxygen plasma, cleaning the Ni/Pt layer, and stripping unreacted Pt from the cleaned Ni/Pt layer, e.g., with a second application of Aqua Regia.
US08883585B1 Fin field-effect transistors and fabrication method thereof
A method is provided for fabricating a fin field-effect transistor. The method includes providing a semiconductor substrate having one or more first fins and second fins; and forming a first doping layer covering the first fins and the second fins. The method also includes forming an isolation layer to isolate adjacent fins; and forming a gate structure stretching across top and sidewalls of the first fins. Further, the method includes forming a source region and a drain region in the fins at both sides of the gate structure; and forming a dielectric layer on the isolation layer. Further, the method also includes forming a first through hole in the dielectric layer to expose a portion of the first doping layer on a top of the second fins; and forming a first conductive via in the first through hole to connect with a bias control voltage.
US08883584B2 Method of manufacturing semiconductor device with well etched spacer
A method of manufacturing a semiconductor device is disclosed. The method may comprise: forming a gate stack on a substrate; depositing a dielectric layer on the substrate and the gate stack; performing a main etching operation on the dielectric layer to form a spacer, with a remainder of the dielectric layer left on the substrate; and performing an over etching operation to remove the remainder of the dielectric layer. According to the method disclosed herein, two etching operations where an etching gas comprises a helium gas are performed, without forming an etching stop layer of silicon oxide. As a result, it is possible to reduce damages to the substrate and also to reduce the process complexity. Further, it is possible to optimize a threshold voltage, effectively reduce an EOT, and enhance a gate control capability and a driving current.
US08883583B2 Semiconductor devices, transistors, and methods of manufacture thereof
Semiconductor devices, transistors, and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes a gate dielectric disposed over a workpiece, a gate disposed over the gate dielectric, and a spacer disposed over sidewalls of the gate and the gate dielectric. A source region is disposed proximate the spacer on a first side of the gate, and a drain region is disposed proximate the spacer on a second side of the gate. A metal layer is disposed over the source region and the drain region. The metal layer extends beneath the spacers by about 25% or greater than a width of the spacers.
US08883582B2 High-K gate electrode structure formed after transistor fabrication by using a spacer
During a replacement gate approach, the inverse tapering of the opening obtained after removal of the polysilicon material may be reduced by depositing a spacer layer and forming corresponding spacer elements on inner sidewalls of the opening. Consequently, the metal-containing gate electrode material and the high-k dielectric material may be deposited with enhanced reliability.
US08883581B2 Compound semiconductor device and method for manufacturing the same
A compound semiconductor device includes a compound semiconductor composite structure in which two-dimensional electron gas is generated; and an electrode that is formed on the compound semiconductor composite structure, wherein the compound semiconductor composite structure includes a p-type semiconductor layer below a portion where the two-dimensional electron gas is generated, and the p-type semiconductor layer includes a portion containing a larger amount of an ionized acceptor than other portions of the p-type semiconductor layer, the portion being located below the electrode.
US08883580B2 Trench metal oxide semiconductor with recessed trench material and remote contacts
Remote contacts to the polysilicon regions of a trench metal oxide semiconductor (MOS) barrier Schottky (TMBS) device, as well as to the polysilicon regions of a MOS field effect transistor (MOSFET) section and of a TMBS section in a monolithically integrated TMBS and MOSFET (SKYFET) device, are employed. The polysilicon is recessed relative to adjacent mesas. Contact of the source metal to the polysilicon regions of the TMBS section is made through an extension of the polysilicon to outside the active region of the TMBS section. This change in the device architecture relieves the need to remove all of the oxides from both the polysilicon and silicon mesa regions of the TMBS section prior to the contact step. As a consequence, encroachment of contact metal into the sidewalls of the trenches in a TMBS device, or in a SKYFET device, is avoided.
US08883578B2 Strained silicon nFET and silicon germanium pFET on same wafer
Various embodiments form silicon and silicon germanium fins on a semiconductor wafer. In one embodiment a semiconductor wafer is obtained. The semiconductor wafer comprises a substrate, a dielectric layer, and a semiconductor layer including silicon germanium (SiGe). At least one SiGe fin is formed from at least a first SiGe region of the semiconductor layer in at least one PFET region of the semiconductor wafer. Strained silicon is epitaxially grown on at least a second SiGe region of the semiconductor layer. At least one strained silicon fin is formed from the strained silicon in at least one NFET region of the semiconductor wafer.
US08883573B2 Isolation for nanowire devices
The present disclosure relates to the field of fabricating microelectronic devices. In at least one embodiment, the present disclosure relates to forming an isolated nanowire, wherein isolation structure adjacent the nanowire provides a substantially level surface for the formation of microelectronic structures thereon.
US08883572B2 Manufacturing method of low temperature poly-silicon TFT array substrate
A manufacturing method of an LTPS-TFT array substrate is provided. The exemplary method comprises a step of sequentially forming a poly-silicon layer and a data-line-metal layer on a base substrate, and performing a patterning process by using a third mask to simultaneously form an active layer and source and drain electrodes, the active layer being provided on the gate insulating layer and corresponding to the gate electrode, and the source and drain electrodes being provided on the active layer.
US08883568B2 Method providing radial addressing of nanowires
Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded NWs where each shell contains one of a plurality of different shell materials; and differentiating individual ones of the NWs from one another by selectively removing or not removing shell material within areas to be electrically coupled to individual ones of a plurality of mesowires (MWs). Also disclosed is a nanowire array that contains radially encoded NWs, and a computer program product useful in forming a nanowire array.
US08883565B2 Separation of semiconductor devices from a wafer carrier
In accordance with an embodiment of the present invention, a semiconductor device is manufactured by arranging a plurality of semiconductor devices on a frame with an adhesive foil. The plurality of semiconductor devices is attached to the adhesive foil. The plurality of semiconductor devices is removed from the frame with the adhesive foil using a carbon dioxide snow jet and/or a laser process.
US08883561B2 Semiconductor device and method of embedding TSV semiconductor die within encapsulant with TMV for vertical interconnect in POP
A semiconductor device has a carrier or first conductive layer with a plurality of TSV semiconductor die mounted over the carrier or first conductive layer. An encapsulant is deposited around the first semiconductor die and over the carrier or first conductive layer to embed the first semiconductor die. A conductive TMV is formed through the encapsulant. A second conductive layer is formed over a first surface of the encapsulant. A first insulating layer is formed over the first surface of the encapsulant while exposing portions of the second conductive layer. A second insulating layer is formed over the second surface of the encapsulant while exposing portions of the first conductive layer. Alternatively, a first interconnect structure is formed over the first surface of the encapsulant. The carrier is removed and a second interconnect structure is formed over a second surface of the encapsulant.
US08883559B2 Semiconductor device and method of forming adhesive material to secure semiconductor die to carrier in WLCSP
A semiconductor device is made by providing a temporary carrier and providing a semiconductor die having a plurality of bumps formed on its active surface. An adhesive material is deposited as a plurality of islands or bumps on the carrier or active surface of the semiconductor die. The adhesive layer can also be deposited as a continuous layer over the carrier or active surface of the die. The semiconductor die is mounted to the carrier. An encapsulant is deposited over the die and carrier. The adhesive material holds the semiconductor die in place to the carrier while depositing the encapsulant. An interconnect structure is formed over the active surface of the die. The interconnect structure is electrically connected to the bumps of the semiconductor die. The adhesive material can be removed prior to forming the interconnect structure, or the interconnect structure can be formed over the adhesive material.
US08883558B2 Semiconductor device and method for manufacturing the same
An object is, in a thin film transistor in which an oxide semiconductor is used as an active layer, to prevent change in composition, film quality, an interface, or the like of an oxide semiconductor region serving as an active layer, and to stabilize electrical characteristics of the thin film transistor. In a thin film transistor in which a first oxide semiconductor region is used as an active layer, a second oxide semiconductor region having lower electrical conductivity than the first oxide semiconductor region is formed between the first oxide semiconductor region and a protective insulating layer for the thin film transistor, whereby the second oxide semiconductor region serves as a protective layer for the first oxide semiconductor region; thus, change in composition or deterioration in film quality of the first oxide semiconductor region can be prevented, and electrical characteristics of the thin film transistor can be stabilized.
US08883554B2 Method for manufacturing a semiconductor device using an oxide semiconductor
In a manufacturing process of a semiconductor device formed using a thin film transistor, an object is to provide a technique by which the number of photomasks can be reduced, manufacturing cost can be reduced, and improvement in productivity and reliability can be achieved. A main point is that a film forming a channel protective layer is formed over an oxide semiconductor layer having a light-transmitting property, a positive photoresist is formed over the film forming a channel protective layer, and a channel protective layer is selectively formed over a channel formation region in the oxide semiconductor layer by using a back surface light exposure method.
US08883547B2 Production of thin films having photovoltaic properties, comprising depositing an alternate I/III or III/I multi-layer structure and annealing said structure
The invention relates to the production of a thin film having photovoltaic properties, containing a I-III-VI2-type alloy and deposited by electrolysis, including the following steps: (a) successive deposits of layers of metallic elements I and III; and (b) thermal post-treatment with the addition of element VI. In particular, step (a) comprises the following operations: (a1) depositing a multi-layer structure comprising at least two layers of element I and two layers of element III, deposited in an alternate manner, and (a2) annealing said structure before adding element VI in order to obtain a I-III alloy.
US08883544B2 Method of forming an image device
A method of forming of an image sensor device includes an isolation well formed in a pixel region of a substrate. The isolation well has a first conductivity type. A gate stack is formed over the isolation well on the substrate. A mask layer is formed over the isolation well and covering at least a majority portion of the gate stack. A plurality of dopants is implanted in the pixel region, using the gate stack and the mask layer as masks, to form doped isolation features. The plurality of dopants has the first conductivity type. A source region and a drain region are formed on opposite sides of the gate stack in the substrate. The source region and the drain region have a second conductivity type opposite to the A conductivity.
US08883535B2 Microelectromechanical system devices having through substrate vias and methods for the fabrication thereof
Methods for the fabrication of a Microelectromechanical Systems (“MEMS”) device are provided. In one embodiment, the MEMS device fabrication method includes forming a via opening extending through a sacrificial layer and into a substrate over which the sacrificial layer has been formed. A body of electrically-conductive material is deposited over the sacrificial layer and into the via opening to produce an unpatterned transducer layer and a filled via in ohmic contact with the unpatterned transducer layer. The unpatterned transducer layer is then patterned to define, at least in part, a primary transducer structure. At least a portion of the sacrificial layer is removed to release at least one movable component of the primary transducer structure. A backside conductor, such as a bond pad, is then produced over a bottom surface of the substrate and electrically coupled to the filled via.
US08883532B2 Organic EL display device and manufacturing method of the same
Disclosed herein is an organic EL display device including, on a substrate: lower electrodes; first hole injection/transport layers; second organic light-emitting layers of colors other than blue; a blue first organic light-emitting layer; electron injection/transport layers; and an upper electrode.
US08883528B2 Methods of producing light emitting device with phosphor wavelength conversion
A method of fabricating a light emitting device comprises: mounting a light emitting diode chip in a package; heating the light emitting diode chip package assembly to a pre-selected temperature; and dispensing a pre-selected volume of a mixture of at least one phosphor and a light transmissive thermosetting material (silicone, epoxy) on a surface of the chip. The pre-selected volume and temperature are selected such that the phosphor/material mixture flows over the entire light emitting surface of the chip before curing. In an alternative method, using a light transmissive UV curable material such as an epoxy, the phosphor/material mixture is irradiated with UV radiation after a pre-selected time to cure the material. The pre-selected volume and pre-selected time are selected such that the phosphor/material mixture flows over at least the light emitting surface of the chip before curing.
US08883523B2 Method for detecting pattern offset amount of exposed regions and detecting mark
A method for detecting a patter offset amount of exposed regions comprises forming at least one pair of conductive detecting marks with a predetermined position relationship by a patterning process including two exposing processes; detecting an electrical characteristic of the at least one pair conductive detecting marks, if the detected electrical characteristic does not meet a predetermined position relationship, it is determined that the pattern offset amount of the exposed regions in two exposure steps is not qualified; and if the detected electrical characteristic meets the predetermined position relationship, it is determined that the pattern offset amount of the exposed regions in two exposure steps is qualified.
US08883518B2 Systems and methods of fluidic sample processing
The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
US08883515B2 Apparatus, system, and method of processing biopsy specimen
A biopsy pipette with a filter attached in an internal compartment of a pipette designed to prevent lodging and possible loss of the tissue specimen for analysis. A biopsy test tube may be provided with a biopsy bag attached in the internal compartment of the test tube. Further, a biopsy cassette may be provided with an opening configured to receive a pipette. An automated and non-automated system and method of using the biopsy pipette, biopsy test tube, and biopsy cassette in the processing of biopsy specimen is also disclosed.
US08883514B2 Chemiluminescent compositions, enhancing reagents for chemiluminescence and methods for the preparation and use thereof
A enhancing reagent for enhancing chemiluminescence of 1,2-dioxetane compounds and a method for using the enhancing reagent to enhance chemiluminescence are provided, in which the enhancing reagent contains a multi-alkyl quaternary ammonium salt of Formula I. A chemiluminescent composition with a 1,2-dioxetane compound as a substrate and a kit thereof are further provided, which contain a 1,2-dioxetane compound and a multi-alkyl quaternary ammonium salt of Formula I.
US08883508B2 Method and apparatus for determining formation fluid composition
In some embodiments, apparatus and systems, as well as methods, may operate to draw a formation fluid sample into a sampling port included in a down hole tool, to vaporize some part of the fluid sample to substantially fill an injection port with a gas phase, to differentiate gas components in the gas phase to provide differentiated gas components along a concentration gradient, to detect the differentiated gas components, and to determine a fingerprint of the differentiated gas components. Other apparatus, systems, and methods are disclosed.
US08883506B2 Kits comprising linear DNAs for sustained polypeptide expression using synthetic, modified RNAs
Described herein are synthetic, modified RNAs for changing the phenotype of a cell, such as expressing a polypeptide or altering the developmental potential. Accordingly, provided herein are compositions, methods, and kits comprising synthetic, modified RNAs for changing the phenotype of a cell or cells. These methods, compositions, and kits comprising synthetic, modified RNAs can be used either to express a desired protein in a cell or tissue, or to change the differentiated phenotype of a cell to that of another, desired cell type.
US08883498B2 Method for inducing differentiation of pluripotent stem cells into skeletal muscle or skeletal muscle progenitor cells
A method for inducing the differentiation of pluripotent stem cells into skeletal muscle or skeletal muscle progenitor cells is provided. Specifically, a method for producing artificial skeletal muscle or skeletal muscle progenitor cells from human pluripotent stem cells is provided, comprising the following steps of: (1) culturing human pluripotent stem cells by suspension culture; (2) culturing a cell population after suspension culture by adhesion culture; (3) dissociating cells after adhesion culture; and (4) culturing the dissociated cells by adhesion culture. Artificial skeletal muscle or induced skeletal muscle progenitor cells prepared by the method are also provided.
US08883497B2 Human myeloid derived suppressor cell cancer markers
Provided herein are methods for determining the presence of cancer (malignant versus benign), monitoring the progression of cancer, monitoring cancer relapse, monitoring the response to cancer therapy, or cancer staging in a subject, by evaluating CD33+/HLA-DRlow, CD14+/HLA-DRlow, CD66b+/HLA-DRlow or, CD11b+/HLA-DRlow MDSC for activation of a transcription factor. Transcription factors include, but are not limited to, STAT3, pSTAT3, HIF1α, or C/EBPβ. The MDSC phenotype can be CD33+HLA-DRlowHIF1α+/STAT3+, CD14+HLA-DRlowHIF1α+/STAT3+/pSTAT3+/C/EBPb+, CD66b+HLA-DRlowHIF1α+/STAT3+/pSTAT3+/C/EBPb+, CD33+HLA-DRlowHIF1α+/STAT3+/pSTAT3+/C/EBPb+, CD11b+HLA-DRlowHIF1α+/STAT3+/pSTAT3+/C/EBPb+, or CD11b+HLA-DRlowC/EBPβ+. Also provided herein are methods for inducing human MDSC from healthy donor peripheral blood mononuclear cells (PBMC) by co-culturing PBMC with human solid tumor cell lines and subsequently measuring their suppressive ability.
US08883496B2 Humanized FcgR mice
Genetically modified non-human animals and methods and compositions for making and using them are provided, wherein the genetic modification comprises a deletion of the endogenous low affinity FcγR locus, and wherein the mouse is capable of expressing a functional FcRγ-chain. Genetically modified mice are described, including mice that express low affinity human FcγR genes from the endogenous FcγR locus, and wherein the mice comprise a functional FcRγ-chain. Genetically modified mice that express up to five low affinity human FcγR genes on accessory cells of the host immune system are provided.
US08883491B2 Systems and methods for counting cells and biomolecules
The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.
US08883488B2 Detection of food threat agents and food-borne pathogens
Disclosed are novel primers for use in the molecular detection of food-threat agents and food-borne pathogens. The primers may be used in combination for the rapid, high-throughput screening PCR-based techniques to simultaneously detect multiple food safety biothreat agents. The multiplex-detection methods have improved sensitivity and specificity for the detection of multiple high-impact food-borne pathogens simultaneously. Real-time PCR assaying techniques using such primers include microarrays and multiplex single-tube arrays, the latter optionally simultaneously with TaqMan probes.
US08883487B2 Molecular diagnostics system and methods
The present invention relates to automated devices and methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of nucleic acids, all in a convenient and portable manner. The invention is particularly suited for use in point-of-care medical diagnostic testing.
US08883485B2 Oxidative decolorization of dyes with enzymatically generated peracid method, composition and kit of parts
Described are compositions and methods for the decolorization of dye molecules in an aqueous medium using enzymatically-generated peracid.
US08883481B2 Reverse genetics methods for virus rescue
A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
US08883478B2 Methods of preparing tissues for xenotransplantation using α-galactosidases
This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family of α3 glycosidases, used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and the Galili antigen from non-human animal tissues, thereby converting these to non-immunogenic cells and tissues suitable for transplantation.
US08883477B2 Oligoadenylate synthetase (OAS)
The invention describes novel pharmaceutical compositions for the treatment of virus infections and cancer. The pharmaceutical compositions include mutant oligoadenylate synthetases (OAS) that have either enhanced cell permeability, reduced oxidative potential, improved antiviral activity, improved enzymatic activity, or absent enzymatic activity. The pharmaceutical compositions have improved drug properties and retain or have enhanced antiviral activity relative to their native forms. The pharmaceutical compositions further include chemically modified oligoadenylate synthetases, such chemical modifications being designed to increase serum stability and reduce immunogenicity in vivo. Such chemical modifications further increase drug stability and manufacturability in vitro. Compositions composed of more than ninety novel modifications are described. Also described are antibodies to polypeptides of the invention.
US08883475B2 Enone reductases
The disclosure relates to engineered enone reductase polypeptides having improved properties, polynucleotides encoding the engineered polypeptides, related vectors, host cells, and methods for making the engineered enone reductase polypeptides. The disclosure also provides methods of using the engineered enone reductase polypeptides for chemical transformations.
US08883472B2 Process for removing water from aqueous solutions of proteins
A method for extracting water from an aqueous solution of a protein comprising the steps of: (a) intermixing the aqueous solution of the protein with a sufficient quantity of at least one glycol ether at a temperature at least 30 centigrade degrees above the lower critical solution temperature (LCST), preferably at least 20 centigrade degrees above the LCST, and most preferably at least 10 degrees above the LCST, to form a suspension comprising a concentrated aqueous protein phase and a liquid organic phase comprising said at least one glycol ether and at least 10 percent water extracted from the aqueous solution of the protein, wherein the glycol ether has an inverse solubility in water, with the proviso that the solubility of the glycol ether in water is significantly less than the solubility of water in the glycol ether, and the glycol ether does not significantly deactivate the protein, and (b) separating the concentrated aqueous protein phase formed in step (a) from at least a portion of the liquid organic phase.
US08883471B2 Materials for magnetizing cells and magnetic manipulation
A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.
US08883466B2 Bacterial cells exhibiting formate dehydrogenase activity for the manufacture of succinic acid
The present invention relates to a bacterial cell of the genus Pasteurella comprising a heterologous polypeptide having formate dehydrogenase activity. The present invention also relates to a method of manufacturing succinic acid and the use of the bacterial cell for the manufacture of succinic acid.
US08883461B2 Process for the production of violacein and its derivative deoxyviolacein containing bioactive pigment from Chromobacterium sp. (MTCC5522)
The present invention discloses a process for producing purple-blue natural pigment containing violacein and its derivative (deoxyviolacein) using Chromobacterium sp. NIIST-CKK-01 (MTCC 5522, NCIM 5341; Genbank Accession No. FJ982784). The method comprises the steps of maintaining and growing the bacterium in a specific medium under defined conditions of pH, temperature and agitation. At the end of incubation, pigment and biomass is separated from the culture broth, pigment is recovered from the biomass through solvent extraction and finally pigment is concentrated by drying.
US08883460B2 L-ornithine or L-arginine producing strain and method for producing L-ornithine or L-arginine
The present invention relates to a polynucleotide that is active to an acetyl glutamate synthase and acetyl ornithinase which are associated with ornithine or arginine biosynthesis from Corynebacterium glutamicum. The present invention also relates to a polypeptide encoded by said polynucleotide, a recombinant vector comprising said polynucleotide, to a transformant obtained by introducing said recombinant vector to a host microorganism for producing L-ornithine or L-arginine, and transforming the recombinant vector, and to a method for producing L-ornithine or L-arginine by culturing said transformant. The activity of the transformant of the present invention to an acetyl glutamate synthase and acetyl ornithinase is increased as compared to an intrinsic activity, and thus L-ornithine or L-arginine can be produced, at a high yield rate, from the transformant of the present invention.
US08883459B2 Process for production of cis-4-hydroxy-L-proline
Development of a method of economically and efficiently producing cis-4-hydroxy-L-proline. The present invention provides L-proline cis-4-hydroxylase. This enzyme may be derived from Lotus corniculatus rhizobia, Mesorhizobium loti or Medicago sativa rhizobia, Sinorhizobium meliloti. The present invention provides a method of producing cis-4-hydroxy-L-proline from L-proline by using this enzyme. The present invention provides a recombinant vector containing a polynucleotide encoding the enzyme and a transformant containing the vector.
US08883458B2 Process for preparing L-amino acids using improved strains of the Enterobacteriaceae family
The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family, characterized in that a) the desired L-amino acid-producing microorganisms, in which the yjcG-ORF, or nucleotide sequences or alleles encoding the gene product, is/are enhanced, in particular overexpressed, is cultured in a medium under conditions under which the desired L-amino acid is accumulated in the medium or in the cells, and b) the desired L-amino acid is isolated, with, where appropriate, constituents of the fermentation broth, and/or the biomass remaining in its/their entirety or in portions (from ≧0 to 100%) in the isolated product or being removed completely.
US08883452B2 K5 heparosan fermentation and purification
A method for the production of heparosan from fermentation culture of E. coli K5 suitable for industrial production, exhibiting superior yield and purity, smaller culture volumes, faster growth, and lower costs.
US08883448B2 Mutated ras peptides for generation of CD8+ cytotoxic T lymphocytes
Mutant ras oncogene peptides may induce specific anti-ras cellular immune responses in vaccinated patients. Moreover, a human CD8+ CTL epitope(s) reflecting a specific point mutation in the K-ras oncogene at codon 12 was identified. The mutant ras peptide has implications for both active and passive immunotherapies in selected carcinoma patients. A nested 10-mer peptide was identified [i.e., ras5-14(Asp12)], which was shown to bind to HLA-A2 and display specific functional capacity for expansion of the in vivo-primed CD8+ CTL precursors.
US08883447B2 Anti-GLP-1R antibodies and their uses
The present invention relates to antibodies reactive with GLP-1R, and methods of making and using them.
US08883446B2 Human long pentraxin 3 expression system and uses thereof
The present invention relates to an eukaryotic expression vector comprising a nucleotide sequence encoding for the human long pentraxin PTX3 protein under the control of an effective promoter and a nucleotide sequence encoding for a selectable marker, recombinant human cell able to provide expression of proteins encoded by the vector and method for the production of the human long pentraxin PTX3 protein.
US08883445B2 Protein glycosylation modification in methylotrophic yeast
The present invention provides genetically engineered strains of methylotrophic yeast including Pichia and especially Pichia pastoris capable of producing proteins with reduced or modified glycosylation. Methods of producing glycoproteins with reduced and/or modified glycosylation using such genetically engineered strains of Pichia are also provided. Vectors, which comprise coding sequences for α-1,2-mannosidase I, glucosidase II, GlcNAc-tranferase I and mannosidase II or comprising OCH1 disrupting sequence, for transforming methylotrophic yeasts are contemplated by the present invention. Kit for providing the comtemplated vectors are also included in this invention.
US08883443B2 Method for producing zeaxanthin by fermentation
A method for microbiologically producing zeaxanthin at high concentration and low cost while suppressing production of gluconic acid is presented. Specifically, a method for producing carotenoids containing zeaxanthin by culturing a bacterium producing carotenoids containing zeaxanthin in a medium containing biotin is provided.
US08883442B2 Culture medium, method for culturing Listeria, and method for detecting Listeria
There are disclosed a culture media and culture supplements for cultivating microorganisms, including Listeria spp and methods for culturing microorganisms including Listeria spp. There are also disclosed methods for detecting the presence of microorganisms including Listeria spp in samples.
US08883441B2 Method for detecting and counting micro-organisms in a sample
A method for detecting and counting the microorganisms in a sample is described. The method comprises: a) selectively enriching the microorganism sought in the sample, b) inducing or activating at least one enzymatic activity of the microorganism, c) immunomagnetically concentrating the microorganism, d) fluorescently labeling the microorganism, and e) detecting and analyzing the fluorescence making possible the numeration or counting of the microorganisms sought by flow cytometry, filtration cytometry or fluorescence microscopy.
US08883434B2 Mutant enzyme and application thereof
An object is to provide a novel enzyme that exhibits glucose dehydrogenase activity. Furthermore, another object is to provide a novel method pertaining to enzyme modification. Provided is a mutated enzyme containing an amino acid sequence wherein one or at least two amino acids selected from the group consisting of (1) to (13) are substituted with another amino acid in the amino acid sequence of a microorganism-derived glucose oxidase: (1) the amino acid corresponding to the amino acid at position 115 of the amino acid sequence of SEQ ID NO: 1; (2) the amino acid corresponding to the amino acid at position 131 of the amino acid sequence of SEQ ID NO: 1; (3) the amino acid corresponding to the amino acid at position 132 of the amino acid sequence of SEQ ID NO: 1; (4) the amino acid corresponding to the amino acid at position 193 of the amino acid sequence of SEQ ID NO: 1; (5) the amino acid corresponding to the amino acid at position 353 of the amino acid sequence of SEQ ID NO: 1; (6) the amino acid corresponding to the amino acid at position 436 of the amino acid sequence of SEQ ID NO: 1; (7) the amino acid corresponding to the amino acid at position 446 of the amino acid sequence of SEQ ID NO: 1; (8) the amino acid corresponding to the amino acid at position 472 of the amino acid sequence of SEQ ID NO: 1; (9) the amino acid corresponding to the amino acid at position 511 of the amino acid sequence of SEQ ID NO: 1; (10) the amino acid corresponding to the amino acid at position 535 of the amino acid sequence of SEQ ID NO: 1; (11) the amino acid corresponding to the amino acid at position 537 of the amino acid sequence of SEQ ID NO: 1; (12) the amino acid corresponding to the amino acid at position 582 of the amino acid sequence of SEQ ID NO: 1; and (13) the amino acid corresponding to the amino acid at position 583 of the amino acid sequence of SEQ ID NO: 1.
US08883432B2 Coelenterazine analogues and coelenteramide analogues
Coelenterazine analogs with different luminescence properties from conventional ones and coelenteramide analogs with different fluorescence properties from conventional ones have been desired. The invention provides coelenterazine analogs modified at the 8-position of coelenterazine and coelenteramide analogs modified at the 2- or 3-position of coelenteramide.
US08883430B2 Enhanced efficiency of induced pluripotent stem cell generation from human somatic cells
A substantially pure population of human somatic cells that have enhanced potential to become induced pluripotent stem cells (iPS cells) is provided. Also provided are methods for generating this population of cells and methods for generating iPS cells from this population of cells.
US08883429B2 Viral diagnostics
The present disclosure provides methods for determining whether a subject is infected with lymphocytic choriomeningitis virus (LCMV). These methods include obtaining a sample from a subject with increased susceptibility to LCMV infection, contacting the sample with one or more compositions for detecting LCMV, and determining whether the one or more compositions for detecting LCMV is associated with a marker of LCMV from the sample, wherein detection of an association indicates that that the subject is infected with LCMV.
US08883424B2 Use of microfluidic systems in the detection of target analytes using microsphere arrays
The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.
US08883423B2 NMR systems and methods for the rapid detection of analytes
This invention features systems and methods for the detection of analytes, and their use in the treatment and diagnosis of disease.
US08883420B2 Process of clean cloning
A process of inserting a nucleic acid sequence of interest into an acceptor nucleic acid is provided. The process comprises amplifying by PCR a DNA comprising in the following order a sequence segment U, a nucleic acid sequence segment of known nucleotide sequence K2, and a nucleic acid sequence segment of known sequence K3. The process further comprises treating the linear double-stranded DNA molecules from the PCR amplification with an exonuclease to obtain a single-stranded overhang at the first end of the DNA and a single-stranded overhang comprising nucleic acid segments K2 and K3 at the second end of the DNA. The process additionally comprises annealing the product of the exonuclease treatment to a linearized double-stranded acceptor nucleic acid which has been designed to complement the single-stranded overhangs of the product of the exonuclease treatment.
US08883414B2 Methods for detecting human papilloma virus-associated cancers
The present invention provides probes and methods of use thereof in the diagnosis and/or prognosis of certain types of cancers, particularly human papillomavirus (HPV)-associated cancers. The probes are designed for hybridization with genomic material in a manner indicative of one or more aberrations in the genetic material present in the test sample. The identified aberrations are biomarkers of HPV-associated cancer. The methods of the invention comprise contacting a sample to one or more probes, allowing any genetic material in the sample to hybridize to the genomic regions provided in the probes, analyzing the hybridizations, and analyzing the hybridizations to identify detected aberrations as biomarkers indicative of HPV-associated cancer progression.
US08883413B2 Compstatin analogs with improved activity
Compounds comprising peptides and peptidomimetics capable of binding the C3 protein and inhibiting complement activation are disclosed. These compounds display improved complement activation-inhibitory activity as compared with currently available compounds. Isolated nucleic acid molecules encoding the peptides are also disclosed.
US08883410B2 Method for determining the stability of organic methyleneamines in the presence of semicarbazide-sensitive amine oxidase
The present invention provides methods for determining the stability of methyleneamine, methyleneamine-like compounds or compounds containing a methyleneamine moiety in the presence of semicarbazide-sensitive amine oxidase (SSAO) or a biological sample containing SSAO activity. The disclosed methods may be configured in an assay format for high throughput screening applications.
US08883409B1 Method of reducing pathogens in whole blood by illuminating with ultraviolet light under low oxygen conditions
Disclosed are methods for pathogen reduction in blood by illuminating with UV light while taking steps for preservation of blood components and reducing oxidative damage from reactive oxygen species generated during UV light exposure. Fresh whole donor blood or products derived therefrom may be submitted to UV light treatment while in a low oxygenation state defined by a partial oxygen pressure below a normal level. Such low oxygenation state occurs naturally shortly after blood collection or may be induced by exposure to low-oxygen environment, reducing temperature or by other disclosed steps.
US08883400B2 Compositions and processes for photolithography
Topcoat layer compositions are provided that are applied above a photoresist composition. The compositions find particular applicability to immersion lithography processing.
US08883388B2 Carrier core particle for electrophotographic developer, carrier for electrophotographic developer and electrophotographic developer
A carrier core particle for an electrophotographic developer including a core composition expressed by a general formula: (MnxMgyCaz) FeWO4+V (x+y+z+w=3, −0.003
US08883387B2 Electrostatic image developing toner and manufacturing method of the same, electrostatic image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method
An electrostatic image developing toner of the exemplary embodiment of the invention contains an amorphous first polyester resin of a polycondenzation product of at least a carboxylic acid component and an alcohol component containing rosin, and a second polyester resin having the difference (absolute value) in parameter of solubility relative to the first polyester resin of from about 0.3 (cal/cm3)1/2 to about 3 (cal/cm3)1/2.
US08883386B2 Polyester resin and toner including same
Disclosed herein is a toner for use in an electronic photograph-duplicating process or in an electrostatic printing process, and a polyester resin included in the toner as a binder. The polyester resin comprises lactic acids (D or L-lactic acids) or lactides (D or L-lactides) which are derivative compounds thereof, and dianhydrohexitols which are bio-derived sugar derivatives.
US08883385B2 Toner, development agent, and image forming apparatus using the same
A toner includes a binder resin, a coloring agent, and a releasing agent containing two or more kinds of alkyl monoester compounds having a different number of carbon atoms in a range of from 30 to 50 carbon atoms. The toner has a crystallinity of 10% or more as measured by x-ray diffraction and/or the binder resin is a crystalline resin in an amount of 50% by weight or more of the binder resin. The two or more kinds of alkyl monoester compounds include a component A accounting for the largest amount ranging from 30% by weight to less than 50% by weight of the releasing agent and a component B accounting for the second largest amount ranging from 10% by weight to less than 50% by weight of the releasing agent.
US08883381B2 Image forming apparatus, and processing cartridge
The present invention provides an image forming apparatus including: an electrophotographic photoreceptor; a charging unit; an electrostatic latent image forming unit that forms an electrostatic latent image; a developing unit that develops the electrostatic latent image formed at the electrophotographic photoreceptor by a developer to form a toner image, the developing unit storing the developer containing a toner having toner particles containing a crystalline resin and having a shape factor SF1 of from 100 to 150, a volume average particle diameter of from 3 to 6 μm, and fluorocarbon-based resin particles as an external additive; a transfer unit; and a cleaning unit that cleans the surface of the electrophotographic photoreceptor with a blade containing urethane rubber, the blade disposed applying a pressure to the electrophotographic photoreceptor surface of 0.20 mN/mm or more.
US08883379B2 Resist-protective film-forming composition and patterning process
A pattern is printed by forming a photoresist layer on a wafer, forming a protective film thereon, exposure, and development. The protective film is formed from a protective film-forming composition comprising a novolak resin of a bisphenol compound and a mixture of an alcohol solvent and an ether or aromatic solvent.
US08883376B2 Photosensitive transparent resin composition, production method of color filter, and color filter
With the objective of providing a photosensitive transparent resin composition that is reduced in the exposure illuminance dependency, allows high residual film ratio and little development scum and can stably form a pattern with good resolution, a color filter ensuring little decrease in the transmittance for visible light and enabling display of a high-quality definite image, and a production method thereof, there is provided a photosensitive transparent resin composition containing at least a polymerizable monomer, an alkali-soluble resin, a photopolymerization initiator and a compound represented by the following formula (I): wherein each of R1 and R2 independently represents a hydrogen atom, an alkyl group having a carbon number of 1 to 20 or an aryl group having a carbon number of 6 to 20, R1 and R2 may be the same or different but are not a hydrogen atom at the same time, R1 and R2 may form a cyclic amino group together with the nitrogen atom, each of R3 and R4 independently represents an electron-withdrawing group, and R3 and R4may combine with each other to form a cyclic electron-withdrawing group.
US08883374B2 EUV photoresist encapsulation
A method and system are described for performing extreme ultraviolet photolithographic processing. The method comprises obtaining a substrate comprising a hard mask and a patterned layer of extreme ultraviolet (EUV) photoresist formed above the hard mask, encapsulating the patterned layer of EUV photoresist by forming an encapsulating layer being one of a silicon-oxide, silicon-nitride, silicon-oxynitride, germanium-oxide, germanium-nitride, germanium-oxynitride, silicongermanium-oxide, silicongermanium-nitride, silicongermanium-oxynitride layer on the photoresist and dry etching of the substrate for patterning the hard mask. The encapsulation layer thereby is formed at a temperature below the weakening temperature Tg of the EUV photoresist by using a first precursor being one of the group of silicon-tetrahalogenide, silicon tetrahydride, germanium-tetrahalogenide, germanium tetrahydride, silicongermanium-tetrahalogenide or silicongermanium tetrahydride precursor and an oxygen precursor.
US08883370B2 Fuel cell system operated with liquid gas
A fuel cell system comprises at least one fuel cell with a high-temperature polymer electrolyte membrane. The fuel cell is supplied with liquefied petroleum gas from a supply of liquefied petroleum gas. The liquefied petroleum gas can be directly fed into an anode reaction chamber of the fuel cell without complex reforming. Water vapor is admixed to the liquefied petroleum gas before it enters the anode reaction chamber.
US08883367B2 Catalyst for fuel cell, membrane-electrode assembly including same, and fuel cell system including same
A catalyst for a fuel cell including a carrier and an active metal dispersion that is supported in the carrier is disclosed. The catalyst may have a dispersity (Dp) represented by General Formula 1 and that ranges from between about 0.01 to about 1.0. Dispersity (Dp)={X−X10/(X1−B)}*(B/X)2  [General Formula 1] In the General Formula 1, X, X10, X1, and B are defined the same as described in the specification. A membrane-electrode assembly, and a fuel cell system having the catalyst are also disclosed.
US08883364B2 Manifold insert having distribution guides and fuel cell stack comprising the same
A manifold insert installed in a fuel cell having distribution guides is provided. The manifold insert is configured to form a flow field from an inlet port of fluid to an outlet port connected to a fuel cell stack. This manifold insert includes a plurality of distribution guides that divide the flow field from the inlet port to the outlet port such that the fuel cell stack is divided into a plurality of regions according to the distance from the inlet port. The distribution guides have surfaces that are at least partially curved such that the flow of the fluid from the inlet port to the outlet port is changed by the curved surfaces and form a plurality of guide flow fields such that the fluid is supplied to the divided regions of the fuel cell stack along the plurality of guide flow fields at different flow rates.
US08883361B2 Voltage control device for a fuel cell
The invention relates to a device for controlling the voltage of a cell of a fuel cell, characterized in that said control device comprises a first transistor (Q1) associated with the cell, which is connected to the cell via the base thereof and to a current generator, and a control voltage source (VRi) inserted between the cell and the first associated transistor (Q1), the control voltage source supplying a control voltage equal to the voltage differential between the first and second threshold voltages, such that: when the cell has a voltage (V1) higher than a first threshold voltage, the first transistor (Q1) has a voltage (Vbe1), at the terminals of the base-emitter junction thereof, which is higher than the second threshold voltage, and which conducts the current, and, when the cell has a voltage (V1) which is lower than the first threshold voltage, the first transistor (Q1) has a voltage (Vbe1), at the terminals of the base-emitter junction thereof, which is lower than the second threshold voltage and which blocks the transmission of the current.
US08883358B2 Metal air secondary battery
An object of the invention is to reduce the charging overvoltage by using a positive electrode member which does not contain a carbon material that causes the generation of lithium carbonate (Li2CO3), and which comprises a metal porous material, thereby suppressing the formation of lithium carbonate (Li2CO3). The metal air secondary battery of the invention is characterized by having a negative electrode member which has metal ions occluded therein and emits metal ions, a positive electrode member which ionizes oxygen, and a separator which is impregnated with an electrolyte and disposed between the negative electrode member and the positive electrode member, wherein the carbon weight in the total weight of a carrier, a catalyst, and a binder constituting the positive electrode member is 50% or less.
US08883352B2 Surface modified lithium-containing composite oxide for cathode active material for lithium ion secondary battery and its production process
To provide a surface modified lithium-containing composite oxide having excellent discharge capacity, volume capacity density, safety, durability for charge and discharge cycles, and high rate property.A surface modified lithium-containing composite oxide, comprising particles of a lithium-containing composite oxide having a predetermined composition and a lithium titanium composite oxide containing lithium, titanium and element Q (wherein Q is at least one element selected from the group consisting of B, Al, Sc, Y and In) contained in the surface layer of the particles, wherein the lithium titanium composite oxide is contained in the surface layer of the particles in a proportion of the total amount of titanium and element Q in the lithium titanium composite oxide contained in the surface layer to the lithium-containing composite oxide particles is from 0.01 to 2 mol %, and the lithium titanium composite oxide has a peak at a diffraction angle 2θ within a range of 43.8±0.5° in powder X-ray diffraction measurement in which CuKα rays are used.
US08883350B2 Process for preparing precursors for transition metal mixed oxides
Process for preparing precursors for transition metal mixed oxides, wherein (A) an optionally basic transition metal carbonate is treated thermally at temperatures in the range from 200 to 900° C., (B) washed one or more times, and (C) then dried.
US08883345B2 Prismatic battery
Provided is a prismatic battery comprising stacked positive electrode plates, negative electrode plates and separator layers therebetween. The positive and negative electrode plates extend beyond a periphery of the electrode stack. The positive electrode plates are fused to form a positive current collector, and the negative electrode plates are fused to form a negative current collector. Both the positive and negative electrode plates comprise a metal foam and are compressed between about 42 and 45% of the original thickness.
US08883343B2 Extended range electric vehicle battery cell packaging for pouch design
A package for a battery cell is disclosed. The package includes a first sheet having a coating layer disposed thereon, a second sheet having a coating layer disposed thereon, the first sheet and the second sheet cooperating to form a cavity to receive the battery cell therein, and a frame disposed adjacent a portion of at least one of the first sheet and the second sheet, wherein the frame is coupled to at least one of the first sheet and the second sheet.
US08883340B2 Secondary battery
A secondary battery including a case having an internal space; an electrode assembly in the case, the electrode assembly including a positive electrode, a negative electrode, a separator between the positive electrode and the negative electrode, and a non-coating portion; a collector plate, the collector plate including a plate section and a protrusion extending from the plate section, the protrusion being inserted into and coupled to the non-coating portion; a collector terminal coupled to one end of the collector plate, the collector terminal protruding upwardly from the case; and a cap plate coupled to a top end of the case and sealing the case.
US08883339B2 Alkali metal-cathode solution battery
An alkali metal-cathode solution storage battery includes an alkali metal anode including at least one alkali metal, a cathode including copper metal, and an alkali ion conducting electrolyte/separator separating the anode and cathode. An anode side electrolyte is between the anode and the separator, and a cathode side electrolyte is between the cathode and the separator. The cathode side electrolyte is selected to have capacity to dissolve metal ions from the alkali metal and electron conducting materials. An ion exchange reaction occurs during operation of the battery within the cathode side electrolyte. The battery can be operated at low temperature (i.e., <100° C.), and provide high specific energy density. The battery can be a planar battery arrangement.
US08883338B2 Dry-battery housing
A dry-battery housing includes an electrode terminal member made of a single wire, a dry-battery housing unit, a flange portion arranged so as to project at first side of the electrode terminal member, a first partition plate projecting along outside for first side of the electrode terminal member, a second partition plate projecting along outside for second of the electrode terminal member, a first fixing plate projecting from the first partition plate toward the second partition plate, a second fixing plate projecting from the second partition plate toward the first partition plate, a flange-root portion including a narrow space portion for allowing insertion and removal of a rim at the first side of the electrode terminal member and an engagement portion arranged between the narrow space portion of the flange-root portion and a border of an opening portion of the dry-battery housing.
US08883332B2 Rechargeable secondary battery
A battery, for example, a secondary battery, includes a case, an electrode assembly in the case, a current collector electrically connected with the electrode assembly, a terminal coupled to the current collector, and a first short circuit inducing member electrically coupled to the electrode assembly and to the current collector. The first short circuit inducing member is arranged between the electrode assembly and the case and the first short circuit inducing member includes a first fuse part.
US08883331B2 Protective circuit module and rechargeable battery including the same
A protective circuit module and a rechargeable battery including the same, the protective circuit module including a circuit board main body having an electrode terminal tab configured to electrically connect to an electrode terminal of a bare cell, a chip-type PTC device on the circuit board main body, and a heat transfer member connected to the chip-type PTC device and the electrode terminal tab.
US08883328B2 Perpendicular magnetic recording medium
A perpendicular magnetic recording medium having a soft magnetic backing layer is disclosed. The medium has reduced Co elution, improved corrosion resistance, and satisfactory electromagnetic transducing characteristics, without providing constraints on the configuration of the protective layer such as, for example, the thickness of the protective layer, film deposition processes or layer configuration.
US08883318B2 Aluminum bonding alloy, and clad material and aluminum bonding composite material each having bonding alloy layer made of the alloy
An aluminum bonding alloy is an Ni—Mg alloy for bonding aluminum and a non-aluminum metal selected from steel, copper, nickel or titanium. The Ni—Mg alloy consists essentially of 0.08-0.90 mass % Mg, and the balance of Ni and inevitable impurities. A clad material includes a non-aluminum metal layer made of the non-aluminum metal and a bonding alloy layer made of the aluminum bonding alloy. The non-aluminum metal layer and the bonding alloy layer are bonded together by pressure welding and diffusion bonding.
US08883316B2 Composite material and high frequency substrate made therefrom
The present invention relates to a composite material, a high-frequency circuit substrate made therefrom and making method thereof. The composite material comprises 20-70 parts by weight of thermosetting mixture, a fiberglass cloth, a powder filler, a flame retardant, and a cure initiator. The thermosetting mixture includes a resin containing vinyl in the amount of more than 60% composed of carbon and hydrogen with its molecular weight being less than 11000, and a solid styryl resin of middle or low molecular weight with unsaturated double bonds. The made high-frequency circuit substrate comprises a plurality of prepregs mutually overlapped, and copper foils respectively covered on both sides of overlapped prepregs. Each prepreg is made from the composite material. The composite material of the present invention enable to readily make prepregs. The high-frequency circuit substrate made from the composite material has low dielectric constant, low dielectric loss tangent, and good heat resistance, and is convenient for process operation. Therefore, the composite material of the present invention is suitable for making circuit substrates of high-frequency electronic equipments.
US08883314B2 Coated articles with improved fingerprint resistance and methods of making same
Described herein are various articles that have improved resistance to the adverse effects observed when tactilely-transferable residue is contacted therewith, along with methods for their manufacture and use. The articles and methods generally make use of an adhesion binder that can be used to form a polymer network around a solvent-soluble fluoropolymer to adhere the fluoropolymer to the surface of the article substrate.
US08883313B2 Modified polytetrafluoroethylene powder and method for producing tetrafluoroethylene polymer
The present invention provides a polytetrafluoroethylene powder having moldability/processability as well as electrical characteristics in microwave bands. The present invention is a modified polytetrafluoroethylene powder which has (1) a dielectric loss tangent at 12 GHz of not higher than 2.0×10−4 and (2) a cylinder extrusion pressure of not higher than 45 MPa at a reduction ratio of 1600.
US08883311B2 Liquid crystal display panel and conductive adhesive, conductive particles and method of manufacturing thereof
The present invention relates to a conductive particle, a conductive adhesive with the conductive particles, a LCD panel with the conductive adhesive, a method of manufacturing of the conductive particle and a method of manufacturing of the conductive adhesive. The conductive particle comprising an outer coating layer of graphite and an inner core of an organic resin enclosed by the outer coating layer, and therefore the conductive particles can have good conductivity as well as good strength and elasticity.
US08883310B2 Metal-containing particle aggregate, metal-containing particle composite member, and method of manufacturing the aggregate and the composite member
A metal-containing particle aggregate of an embodiment of the present invention includes a plurality of core-shell particles. Each of the core-shell particles includes: a core portion that contains at least one magnetic metal element selected from the first group consisting of Fe, Co, and Ni, and at least one metal element selected from the second group consisting of Mg, Al, Si, Ca, Zr, Ti, Hf, Zn, Mn, rare-earth elements, Ba, and Sr; and a shell layer that includes a carbon-containing material layer and an oxide layer that covers at least part of the core portion and includes at least one metal element that belongs to the second group and is contained in the core portion.
US08883306B2 Cold drawn low carbon steel filament and method of manufacturing said filament
A steel filament adapted for the reinforcement of elastomer or for thermoplastic products has a carbon content ranging up to 0.20 per cent by weight. The steel filament is provided with a coating promoting the adhesion with elastomer or thermoplastic products. The steel filament is drawn until a final diameter of less than 0.60 mm and a final tensile strength of more than 1200 MPa. Intermediate heat treatments are avoided so that the carbon footprint of the steel filament is substantially reduced.
US08883305B2 Thermoset resin fibres
The present invention relates to thermoset resin fiber components, composite materials including thermoset resin fiber components, composite articles manufactured using such composite materials and methodologies for manufacturing same. The thermoset resin fiber components may include a single fiber of thermoset resin or a plurality of fibers commingled together. The properties and characteristics of the thermoset resin used are chosen according to the material to be produced therefrom. The thermoset fiber components may be woven into reinforcement fibers to form prepregs. Thermoplastic fibers may be commingled and co-woven with the thermoset fiber components.
US08883302B2 Abrasion resistant cords and ropes
The abrasion resistance of organic fiber based ropes and cords is increased by a outer woven cover of tapes of high molecular weight and more preferably ultrahigh molecular weight polyethylene.
US08883301B2 Coextrusion film and method of making a laminated web
A coextrusion film according to a first embodiment of the invention has a monolithic elastic layer of a thermoplastic elastomer having an exposed outer face and an inner face and a support layer lying on, releasably joined to, and separable from the inner face at an interface.
US08883292B2 Ink composition, and recorded matter, recording method and recording apparatus using the same
An ink composition contains hollow resin particles and an anti-clearing agent preventing the clearing phenomenon of the hollow resin particles.
US08883291B2 Metal oxide coating on surfaces
The present invention provides a method for coating metal oxide on a PDMS surface. The method includes preparing a mixture that contains a sol-gel precursor, reacting the mixture to form a preconverted sol-gel precursor, where the preconverted sol-gel precursor does not diffuse into PDMS and is not in the form of a gel, forming a reactive PDMS surface, applying the preconverted sol-gel precursor onto the reactive PDMS surface, binding the preconverted sol-gel precursor to the re-active PDMS surface, and converting the bound preconverted sol-gel precursor to a metal oxide to form a metal oxide coating on the PDMS surface. The present invention also provides a PDMS microfluidic device where one or more channels of the microfluidic device is provided with a metal oxide coating covalently bound only on the surface of the one or more channels.
US08883290B2 Floor marking tape
A floor marking tape has a structure that retains the adhesive under the tape to prevent the adhesive from being squeezed out from under the tape when the tape is in use on a floor. In one embodiment, the structure is a shoulder that defines a recess that holds the bulk of the adhesive. The shoulder prevents the adhesive from flowing out to the outer edge of the tape. The tape may have beveled edges that limit the unintentional lifting and delamination of the tape from the floor. The upper surface of the tape may be curved from edge-to-edge to limit dirt retention on the tape as well as allowing objects to slide over the tape.
US08883289B2 Fluid philicity/ phobicity adjustable surface structure
The fluid philicity/phobicity adjustable surface structure is provided to hold a liquid. The surface structure includes a base and many small bumps located on the base. The small bumps are boxy in shape. Every small bump has at least one corner boundary, and the corner boundary is defined as a sudden change of the surface orientation. The gap between every two adjacent small bumps is smaller than the shortest cohesion diameter of the liquid. Additionally, the contact angle between the liquid and the hydrophilic hydrophobic adjustable surface structure is θ which satisfies the condition: θ*≦θ≦(180−α)+θ*, where θ* is the contact angle between the base and the liquid, α is the boundary edge angle of the small bump.
US08883288B2 Abrasive article with adhesion promoting layer
An abrasive article includes a backing having a major surface, an adhesion promoting layer overlying the major surface of the backing, and a make layer directly contacting the adhesion promoting layer. The adhesion promoting layer has a thickness of at least about 10 microns and is formed of a polar thermoplastic material, a cross-linkable polymer, or blends thereof.
US08883287B2 Structured material substrates for flexible, stretchable electronics
A flexible and stretchable patterned substrate is provided having a strain-permitting material comprising a patterned conformation that allows the flexible patterned substrate to experience local strain or local strain domains lower than the macroscopic strain of the flexible and stretchable patterned substrate.
US08883284B2 Vapor permeable fabric constructs with static or dynamic antimicrobial compositions
Protective, multi-layered, breathable fabric constructs having dynamic or static antimicrobial compositions incorporated into adhesive components. The flexible constructs employ a fabric layer and a breathable coating layer applied to the fabric. Under certain preferred embodiments, the fabric constructs also employ an energy dissipating fiber material disposed opposite the coating layer. Also, the present invention teaches a method of protecting a valuable or sensitive object from damage caused by corrosion, weather, biomass, or other environmental related conditions using the fabric material. The fabric constructs may be post-formed using heat or other methods to create shaped-to-form covers.
US08883281B2 Multilayer film having pressure sensitive adhesive layer
A multilayer film includes a substrate film having first and second major surfaces and a pressure sensitive adhesive layer disposed on the first major surface of the substrate film. The pressure sensitive adhesive layer includes a curable composition. The multilayer film further includes a release layer disposed on the pressure sensitive adhesive layer opposite the substrate film. The release layer includes a release material and a catalyst to cure the curable composition.
US08883279B2 Fluid-assisted injection molded articles and process
Fluid-assisted injection molding articles and processes for producing the articles are described. In one embodiment, a fluid-assisted injection molded article is formed from a polymeric composition containing a polyethylene terephthalate homopolymer in combination with a polyethylene terephthalate copolymer. The polyethylene terephthalate copolymer may comprise a copolymer of polyethylene terephthalate with isophthalic acid. The polymeric composition can also contain a reinforcing agent, such as glass fibers. Products made in accordance with the present disclosure have shown dramatically improved surface characteristics. In particular, pitting on the surface of the molded article is minimized.
US08883278B2 Container having blind holes for pinhole resistance and associated method
A container that has a laminate that has a substrate with a gloss layer and a matte layer is provided. A portion of the laminate is located at a seal portion of the container, and a plurality of cavities extend through the gloss layer but do not extend through any amount of the matte layer at the portion of the laminate that is located at the seal portion. The plurality of cavities function to reduce the severity of pinholes at the seal portion.
US08883276B2 Recording medium
There is provided a recording medium including a substrate and an ink-receiving layer formed on at least one surface of the substrate, wherein the ink-receiving layer contains an inorganic pigment, a binder, and a compound containing aluminum, silicon, and at least one element selected from Group 2 and 3 elements of the periodic table, and the compound content is in the range of 0.1 mass % to 30 mass % relative to the inorganic pigment content.
US08883272B2 Cellulose acylate film
Provided are a cellulose acylate film used for optical compensation and additives used therefor and, more particularly, is a cellulose acylate film with mechanical physical properties, in particular, very improved modulus affecting film durability.
US08883268B2 Method and device for producing a parylene coating
A method of producing a parylene coating on at least one surface of at least one component includes providing a first gas containing parylene monomers and depositing the parylene monomers on the at least one surface of the component by supplying the first gas containing the parylene monomers by a first nozzle to the at least one surface, wherein the component is disposed in an environment at atmospheric pressure.
US08883266B2 Irradiation assisted nucleation of quantum confinements by atomic layer deposition
A method of fabricating quantum confinements is provided. The method includes depositing, using a deposition apparatus, a material layer on a substrate, where the depositing includes irradiating the layer, before a cycle, during a cycle, and/or after a cycle of the deposition to alter nucleation of quantum confinements in the material layer to control a size and/or a shape of the quantum confinements. The quantum confinements can include quantum wells, nanowires, or quantum dots. The irradiation can be in-situ or ex-situ with respect to the deposition apparatus. The irradiation can include irradiation by photons, electrons, or ions. The deposition is can include atomic layer deposition, chemical vapor deposition, MOCVD, molecular beam epitaxy, evaporation, sputtering, or pulsed-laser deposition.
US08883262B2 Modification of solid surfaces by application of polymer associations thereon
Polymer combinations which contain: at least one first polymer (PZ) containing zwitterionic structural units; and at least one other polymer (P) carrying charged substituents and capable of bonding with the at least one first polymer (PZ), are applied onto the face surface(s) of solid materials to modify the surface properties thereof.
US08883261B2 Artifacts, method of creating such artifacts and methods of using such artifacts
A method for creating an artifact for use with an optical three-dimensional measuring system includes steps of: (a) providing an artifact that comprises an inspection surface, which artifact is configured to be scanned by a non-contact sensor included in the optical three-dimensional measuring system, which artifact comprises at least one of a substantially spherical body and a turbine engine component, and which inspection surface comprises a surface of one of the substantially spherical body and the turbine engine component; (b) heating the artifact to a predetermined temperature; and (c) coating the inspection surface of the heated artifact with an approximately uniform coating of dry film lubricant.
US08883260B2 Apparatus and method for producing carbon
A method and an apparatus for efficiently producing a high-purity CNT assembly of a high specific surface area are provided in which a feedstock gas is contacted to a catalyst in an optimum form for CNT growth.A carbon nanotube producing apparatus of the present invention includes: a synthesis furnace; a gas supply pipe and a gas exhaust pipe in communication with the synthesis furnace; heating means that heats inside of the synthesis furnace to a predetermined temperature; and gas blowing means that blows a feedstock gas into the synthesis furnace after the feedstock gas is supplied through the gas supply pipe. The feedstock gas supplied through the gas supply pipe is supplied into a heating region of the synthesis furnace heated by the heating means, so as to produce a carbon nanotube from a surface of a catalyst layer provided on a base. The feedstock gas is evacuated through the gas exhaust pipe. The carbon nanotube producing apparatus further includes residence time adjusting means that allows the feedstock gas to contact the surface of the catalyst layer on the base in a substantially uniform amount after substantially the same residence time.
US08883258B2 Protective coating of silver
In the method, silver is protected against tarnishing using an Atomic Layer Deposition method. In the Atomic Layer Deposition method, a thin film coating is formed 5 on the surface of silver by depositing successive molecule layers of the coating material. For example aluminum oxide (Al 2O3) or zirconium oxide may be used as the coating material.
US08883257B2 Method for manufacturing gas barrier thin film-coated plastic container
Disclosed herein is a method for producing a plastic container coated with a thin film that is excellent in gas barrier properties, film coloration and film adhesiveness without using an external electrode having a special shape while suppressing deposition of foreign matters such as carbon powders. The method for producing a gas barrier thin film-coated plastic container according to the present invention includes the steps of: housing a plastic container in an external electrode serving as a film-forming unit; placing an internal electrode serving as a raw material gas supply tube in an inside of the plastic container; exhausting gas from an inside of the external electrode by activating a vacuum pump; blowing a raw material gas into the inside of the plastic container under a reduced pressure; and forming a gas barrier thin film on an inner wall surface of the plastic container by generating plasma from the raw material gas, setting a power source frequency of a power source for plasma generation to supply power to the external electrode to be 5.5 to 6.5 MHz.
US08883254B2 Method of synthesizing hollow silica from sodium silicate
Disclosed is a method of synthesizing hollow silica having the size of micrometers from sodium silicate. The method includes fabricating a polystyrene organic template from polystyrene latex, (B) cleaning the polystyrene organic template, (C) exchanging media by using a water-base medium, introducing the cleaned polystyrene organic template and sodium silicate, and preparing a silica-coated organic template by performing an acidic hydrolysis reaction, and (D) cleaning the silica-coated organic template included in the water-base medium by using water. The size of the organic template is adjusted by controlling an amount of introduced AIBN included when the organic template is fabricated. The cleaning of the organic template is preferably performed by using water (H2O). The method further includes (B) removing the organic template by using THF and (F) cleaning the hollow silica having no organic template.
US08883252B2 Antireflective coatings with self-cleaning, moisture resistance and antimicrobial properties
Coated article having antireflective property together with self cleaning, moisture resistance and antimicrobial properties can be prepared with a topmost layer of titanium oxide on an antireflective layer, which can be formed by a sol-gel process. The antireflective layer can comprise a porosity forming agent, or an alkyltrialkoxysilane-based binder. The antireflective coating can comprise silica and titania components, with pores to achieve low index of refraction and titania to achieve self-cleaning and antimicrobial properties.
US08883249B2 Method of producing a perpendicular magnetic recording medium
By improving sliding durability while ensuring a high SNR, an improvement in reliability and a further increase in recording density are to be achieved.The structure of a method of manufacturing a perpendicular magnetic recording medium according to the present invention includes: a main recording layer forming step of forming, on a substrate, at least a main recording layer formed of magnetic particles having a CoCrPt alloy as a main component and a non-magnetic grain boundary part having an oxide as a main component; a split layer forming step of forming a split layer having a Ru alloy or a Co alloy as a main component on the main recording layer; a first heating step of performing a heat treatment on the substrate after the split layer forming step; an auxiliary recording layer forming step of forming an auxiliary recording layer formed of a material having CoCrPt as a main component after the first heating step; a second heating step of performing a heat treatment on the substrate after the auxiliary recording layer forming step; and a protective layer forming step of forming a protective layer having carbon as a main component by CVD after the second heating step.
US08883243B2 Encapsulation agent comprising a pea maltodextrin and/or a pea glucose syrup, compositions containing it and its preparation method
A subject of the present invention is the use of a maltodextrin and/or a glucose syrup obtained, by acid or enzymatic hydrolysis, from a leguminous starch having an amylose content comprised between 25% and 50%, expressed as dry weight relative to the dry weight of starch, for the encapsulation of organic compounds.
US08883240B2 Calcium stable high acyl gellan gum for enhanced colloidal stability in beverages
A low calcium sensitive (calcium stable) high acyl gellan gum is prepared for enhanced colloidal stability in beverages. The low calcium sensitive high acyl gellan gum has superior suspension performance for colloidal stability compared to other high acyl gellan gums. The low calcium sensitive high acyl gellan gum is prepared by adjusting the pH of a gellan fermentation broth (polymer solution) prior to pasteurization and reducing the pasteurization hold time compared to conventional pH levels and hold times.
US08883237B2 Ovenable corrugated paper container
An ovenable paper container containing an inner liner, an outer liner, and an intermediate or corrugated paper layer positioned between the inner liner and the outer liner. The ovenable paper container can be used to heat and/or cook food and then be used as a serving container without the danger of causing burns.
US08883234B2 Fermenter and microwave oven having the same, their controlling method
A fermenter, a microwave oven including the fermenter, and a method of controlling the fermenter and microwave oven are provided. The fermenter includes a fermenter casing having one side open and defining a fermenting chamber, a fermenter door that selectively opens or closes the fermenting chamber, a thermoelectric element that applies heat to the fermenting chamber or absorbs heat from the fermenting chamber, and a current switching device that converts current supplied to the thermoelectric element such that the thermoelectric element absorbs or generates heat. The fermenter may be very conveniently employed and a microwave oven with various functions may also be provided.
US08883232B2 Horse feed and treatment methods
A horse feed mixture and method of treating a horse is disclosed. Feed mixtures disclosed contains more than 15% spelt, vegetable oil and vitamins and have less than 20% by weight fillers and less than 5% by weight sugar. The feed may be used to treat ailments including underweight condition, founder, colic, obesity, ulcers, inflammation, and chronic disease.
US08883231B2 Packaged artificial soft baits
A method for packaging is described for enhancing the attractiveness of an artificial hydrophilic polymeric soft fish bait to fish, comprising: immersing or suspending said soft bait in a package with an aqueous suspension of biological fluids from an animal, the water-soluble fraction of biological fluids from an animal, or an artificial simulated fluid thereof, so that the soft bait absorbs said fluid and an animal odor/flavor components contained therein.
US08883228B2 Composition for heart disease, its active ingredients, method to prepare same and uses thereof
This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.
US08883220B2 Compositions of jasmonate compounds
The disclosure describes nanocarried and/or microcarried jasmonate compounds and their pharmaceutical compositions, as well as use thereof for treating or preventing angiogenesis-related or NF-κB-related disorders. Also disclosed are methods of making the nanocarried and/or microcarried compounds and their compositions.
US08883213B2 Ion exchange resin treated to control swelling
The present invention provides a method and composition are provided for loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle. The drug-loaded resin particle is a sustained-release coated layered pharmaceutical drug-ion exchange resin having a one or more pharmaceutically active drugs applied directly to a non-equilibrated ion exchange resin to form a drug-resin complex. The drug-resin complex then coated is shelf stable.
US08883211B2 Polyoxazolines with inert terminating groups, polyoxazolines prepared from protected initiating groups and related compounds
The present disclosure provides novel functional polyoxazoline derivatives prepared by terminating polyoxazoline polymerization with inert chemical groups. In addition, the present disclosure demonstrates the synthesis of novel electrophilic initiators with protected functional groups capable of initiating oxazoline polymerization and capable of surviving the conditions of polymerization. These initiators are used to synthesize the above inert-terminal polyoxazoline derivatives as well as other polyoxazolines with active terminal groups. Furthermore, the present disclosure provides for polyoxazoline-lipid conjugates and liposomal compositions prepared using such polyoxazoline-lipid conjugates. Methods of using the foregoing to prepare conjugates with target molecules are also disclosed.
US08883208B2 Particles for delivery of nucleic acids and related devices and methods
Embodiments of the invention include devices and methods for the release of nucleic acid complexes. In an embodiment the invention includes a nucleic acid delivery particle. The delivery particle can include a polymeric matrix including a polyethyleneglycol containing copolymer and a nucleic acid complex disposed within the polymeric matrix. The nucleic acid complex can include a nucleic acid and a carrier agent. In an embodiment the invention includes a medical device including a first polymeric matrix comprising a first polymer and a plurality of nucleic acid delivery particles disposed within the first polymeric matrix. The medical device can be configured to release the nucleic acid complex when the medical device is implanted within a subject. Other embodiments are included herein.
US08883206B2 Pharmaceutical composition and administrations thereof
The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
US08883204B2 Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same
The present invention relates to co-extruded pharmaceutical compositions and dosage forms including an active agent, such as an opioid agonist, and an adverse agent, such as an opioid antagonist. Such compositions and dosage forms are useful for preventing or discouraging tampering, abuse, misuse or diversion of a dosage form containing an active pharmaceutical agent, such as an opioid. The present invention also relates to methods of treating a patient with such a dosage form, as well as kits containing such a dosage form with instructions for using the dosage form to treat a patient.
US08883201B2 Solid oral dosage form containing an enhancer
The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
US08883199B2 Administration regime for N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2- ylcarbonylamino]ethoxy}benzamide
N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2-ylcarbonylamino]ethoxy}-benzamide of formula (I): or an addition salt thereof with a pharmaceutically acceptable acid or base, alone or in association with surgery, chemotherapy or hormone therapy treatment or radiotherapy, for use in the treatment of cancer, characterized in that it is administered for 4 consecutive days, that period being followed by 3 consecutive days without any administration of compound of formula (I), with the proviso that the chemotherapy is not FOLFOX.
US08883194B2 Adsorbent-containing hemostatic devices
The present invention utilizes a combination of a porous carrier and an adsorbent such as a molecular sieve to make a more effective hemostatic device to treat wounds in mammalian animals. These hemostatic devices contain additives that do not inhibit hemostasis.
US08883193B2 Cellulosic biocomposites as molecular scaffolds for nano-architectures
Disclosed are composites that comprise regenerated cellulose, a first active substance, a second active substance, and a linker. Methods for preparing the composites that involve the use of ionic liquids are also disclosed. Articles prepared from the disclosed composites and methods of using them are further disclosed.
US08883191B2 Method for producing individually dosed active substance-containing and, in particular, aromatics-containing film-shaped administration forms rapidly disintegrating upon contact with liquid
A method for producing individually dosed active substance-containing and, in particular, aromatic-containing, film-shaped administration form, rapidly disintegrating upon contact with a liquid, wherein the aromatic is present as an internal, liposoluble phase in the form of liquid droplets distributed within an outer, solid but water-soluble phase, is characterized in that the said outer phase contains: at least 40% (w/w) polyvinyl alcohol 0 to 30% (w/w), of a surface-active substance, and that the constituent amount of the inner phase, relative to the outer phase, is between 0.1 and 30% (w/w), in each case relative to the water-free portions.
US08883187B2 Stabilized compositions containing alkaline labile drugs
A stabilized bioadhesive composition containing an alkaline labile drug and a method for its preparation are provided. In one aspect, the composition is a hot-melt extruded (HME) composition comprising a preformed excipient mixture comprising an acidic component and an alkaline thermoplastic matrix-forming material, e.g. polymer. The excipient mixture is formed before blending with an alkaline labile drug. The blend is then hot-melt extruded to form the HME composition. By so doing, the acidic component is able to neutralize or render moderately acidic the excipient mixture. This particular process has been shown to substantially reduce the degradation of an alkaline labile drug during hot-melt extrusion. The excipient mixture softens or melts during hot-melt extrusion. It can dissolve or not dissolve drug-containing particles during extrusion. Various functional excipients can be included in the carrier system to improve process performance and/or improve the chemical or physical properties of the HME composition.
US08883182B2 Method and material for enhanced tissue-biomaterial integration
The present invention provides a composition and method for the covalent binding of a hydrogel to an extracellular matrix (ECM). Therapeutic applications include tissue repair and delivery of drugs or cells.
US08883167B2 Ethanol extract of Antrodia camphorata for inducing apoptosis and preparation method thereof
A preparation method for an ethanol extract of the fruiting body of Antrodia camphorata (EEAC) is provided. The preparation method includes steps of: (a) providing the fruiting body of A. camphorata (AC); (b) extracting the fruiting bodies with a first ethanol solution; and (c) obtaining EEAC. EEAC further can be sequentially extracted or fractioned by n-hexane, ethyl acetate and ethanol, and an n-hexane fraction (FC), an ethyl acetate fraction (FA) and an ethanol fraction (FB) respectively are generated. The growth inhibition and apoptosis induction of leukemia cell line HL 60 are effectively mediated by FA product, in which zhankuic acid A is the bioactive marker. The amount of triterpenoid in the fruiting body of AC can be determined by NMR and HPLC analysis.
US08883164B2 Targeted identification of immunogenic peptides
This invention relates generally to identifying peptide sequences involved in antibody binding to any protein for synthesis of vaccine treatments. This novel method allows for a more manageable vaccine peptide discovery and specific generation of unique immunogenic peptides from self-tumor associated proteins and/or foreign proteins from infectious organisms for specific and/or enhanced expression only in the presence of the antibody.
US08883157B1 Targeting rare human PCSK9 variants for cholesterol treatment
The invention relates to human targets of interest (TOI), anti-TOI ligands, kits compositions and method.
US08883154B2 Antibody-mediated modulation of allergy
The present invention is drawn to antibody-mediated modulation of allergy. In this regard, the present invention discloses a monoclonal antibody, antigen-binding fragment or mimic thereof directed against Group 1 pollen allergens or homologues thereof. Also disclosed herein is the mechanism by which the disclosed monoclonal antibody, antigen binding fragment or mimic thereof will improve immunotherapy of allergic reactions in an individual. It is contemplated that herein that such a monoclonal antibody, antigen binding fragment or mimic thereof may also be useful in treatment of several microbial infections.
US08883153B2 Methods for preventing and treating angioedema
One aspect of the present invention provides a method of treating or preventing angioedema in a patient in need thereof comprising administering to the patient a therapeutically effective amount of an agent that is capable of inhibiting the interaction of HK with gC1q-R. One aspect of the present invention provides a method of treating or preventing vascular permeability in a patient in need thereof comprising administering to the patient a therapeutically effective amount of an agent that is capable of inhibiting the interaction of HK with gC1q-R.
US08883152B2 Anti-cobra toxin antibody fragments and method of producing a VH H library
A method of constructing a VHH library from an immunized camelid, using whole venom or an extract thereof. There is also provided VHH antibody fragments isolated from a library produced in hyperimmunized llama. These VHH antibody fragments were sequenced, and specifically bind α-cobratoxin.
US08883151B2 IL-17 receptor antibody formulation
The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.
US08883149B2 Antibody combinations and use of same for treating cancer
A method of identifying a combination of antibodies with a combined improved anti-tumor activity is provided. The method comprising: (a) identifying binding epitopes of anti ErbB-2 antibodies; and (b) selecting a combination of at least two antibodies of the anti ErbB-2 antibodies exhibiting binding to different epitopes on the ErbB-2, at least one of the different epitopes being localized to a dimerization site of the ErbB-2, the combination of antibodies being with the combined improved anti-tumor activity. Also provided are novel antibody combinations uncovered according to the present teachings.
US08883143B2 Treatment of traumatic-induced migraine headache
A method for selection and treatment of externally caused migraine headache, the method includes identifying a patient group having chronic migraine headache; determining the identified patient group, a specific patient with a post traumatic migraine headache; and administering to the selected patient by injection of a therapeutically effective amount of an invertebrate presynaptic neurotoxin in a pharmaceutically safe form to the selected patient's head or upper neck; administration preferably being on the sites of the trigeminal cervical system, enabling axonal transport of the neurotoxin from distal to central sites; and the administration preferably comprising extramuscular injection of the neurotoxin of suitable dilution (a) over the aponeurotic fascia to enable the neurotoxin to diffuse into distal sensory nerves, in order to concentrate the neurotoxin over the occipital-parietal-frontal head region, or (b) intra-orally, in a foramina of the sphenopalatine ganglion for enabling diffusion of the neurotoxin to the ganglion, or (c) to emerging exit points of nerves including foraminal sites for enabling the neurotoxin access to concentrated nerve bundles at exit points of the foramina.
US08883142B2 Fructosyl peptide oxidase
A reagent measuring a glycated protein, comprising a protease and a protein of any one of [1] to [4] below: [1] a protein comprising the amino acid sequence represented by SEQ ID NO:1; [2] a protein comprising an amino acid sequence with one to ten amino acid deletions, substitutions, or additions in the amino acid sequence represented by SEQ ID NO:1, and having fructosyl peptide oxidase activity; [3] a protein comprising an amino acid sequence having 99% or higher homology to the amino acid sequence represented by SEQ ID NO:1, and having fructosyl peptide oxidase activity; and [4] a protein having fructosyl peptide oxidase activity, which is encoded by an expression plasmid harbored by the Escherichia coli XL1-Blue MRF′ strain deposited under Accession No. FERM BP-11026.
US08883137B2 Compositions comprising selenium-rich yeast and yeast beta-glucan
A nutritional composition comprising by weight: between 0.05 and 30% selenium-enriched yeast; between 1 and 90% yeast beta-glucan; between 0.5 and 60% Vitamin C; and between 0.5 and 40% Vitamin E. The composition features anti-oxidative, anti-aging, cancer-preventing, and immune-stimulating properties.
US08883135B2 Crystalline form of a pyridyl-piperazinyl hepatitis C virus inhibitor
The invention provides crystalline solid forms of (((S)-1-{(S)-2-[4-(4′-{[6-((2R,5S)-2,5-dimethyl-4-methylcarbamoyl-piperazin-1-yl)-pyridine-3-carbonyl]-amino}-2′-trifluoromethoxy-biphenyl-4-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat hepatitis C virus infection, and processes useful for preparing such crystalline solid forms.
US08883134B2 Human interleukin-1 receptor antagonist—hybrid Fc fusion protein
The present disclosure provides a fusion protein comprising IL-1 receptor antagonist fused to a hybrid Fc. Particularly the present disclosure relates to a fusion protein comprising IL-1 receptor antagonist fused to a human immunoglobulin hybrid Fc fragment. In one embodiment, the hybrid Fc fragment comprises IgD and IgG4. Also provided is a pharmaceutical composition comprising the present fusion protein, which are useful for treating autoimmune disease including rheumatoid arthritis, inflammatory bowel disease (Crohn's disease, ulcerative colitis), psoriasis and diabetes and the like. The present fusion protein with excellent efficacy and reduced side effects is qualified for clinical development as therapeutic antibodies to treat autoimmune disease.
US08883133B2 Pharmaceutical compositions comprising polymeric binders with non-hydrolysable their use in treating celiac disease
A pharmaceutical composition comprising a polymeric binder including a high molecular weight synthetic polymer having a backbone constituted of non hydrolysable covalent bonds, said polymer being able to form electrostatic bonds at a pH lower than the isoelectric point of gluten and peptides derived from the degradation of gluten, and being able to bind to gluten or peptides derived from the degradation of gluten in the gastrointestinal tract, and a pharmaceutically acceptable carrier. Methods of using the polymeric binder for binding gluten or a peptide derived from the degradation of gluten, for decreasing the degradation of gluten into toxic peptides or for decreasing interaction of gluten or peptides derived from the degradation of gluten with the gastrointestinal mucosa.
US08883131B2 Composition for the treatment of hair loss and baldness
A synergistic composition, or the use of that composition in the manufacture of a medicament, or a method of treatment including the use of that composition, for the treatment of hair loss and baldness, for combined, sequential or simultaneous administration, in any form, via any biological route. In its optimal embodiment the composition consists, in the form of a lotion: 1600-2400 IU/mL Vitamin A Palmitate, 0.64%-0.96% Thiamine Hydrochloride, 0.64%-0.96% Pyridoxine Hydrochloride, 4.8%-7.2% Niacinamide, 2.85%-5.2% D-Panthenol, 1.6%-2.4% L-Arginine, 3.6%-4.4% Methyl Sulphonyl Methane (MSM), 0.08%-0.12% Ginger Oil, 0.08%-0.12% Cinnamon Oil, 0.0996%-0.1494% Oleoresin Capsicum, 1.3%-1.95% Magnesium, 2.4%-3.6% Zinc, 0.192%-0.288% Manganese, 2.6%-3.9% Urea, 2.4%-3.6% Sodium Glycerophosphate, 4.8%-7.2% L-Lysine HCl, plus Preservatives, Co-solvent (Propylene Glycol), Fragrances, Anti-Oxidant, Cooling agent (Menthol), Emulsifier, and Vehicle (Purified water).
US08883128B2 Cosmetic compositions containing a propylphenylsilsesquioxane resin and a cosmetically-acceptable aromatic solvent
The present invention is directed to a cosmetic composition containing: (a) at least one propylphenylsilsesquioxane resin; (b) at least one cosmetically-acceptable aromatic solvent; (c) at least one colorant, and (d) optionally, at least one co-solvent, and wherein the composition is substantially free of volatile solvents. Also disclosed is a method of imparting lasting shine onto lips by contacting the lips with the above described composition.
US08883126B2 Water-based nail-polish composition
The water-based nail-polish composition includes a mixture of at least one water-based suspension (A) of hard nanoparticles of an acrylic polymer at a glass transition temperature that is greater than or equal to 55° C., in combination with at least one coalescent and/or plasticizing solvent of the polymer; and at least one water-based suspension (B) of nanoparticles of acrylic monomers, partially cross-linked, that have a film formation temperature of less than 15° C. The water-based composition can also contain a solution (C) of an acrylic polymer of low molecular weight that is less than approximately 20,000, with a high acid value, neutralized to a pH of between 7 and 8.5, approximately.
US08883125B2 Cosmetic composition comprising a cucurbic acid compound and a blend of sulfonic and acrylic polymers
The invention relates to a cosmetic composition comprising, in a physiologically acceptable aqueous medium, a cucurbic acid compound of formula (I) in which R1 represents a radical COOR3, R3 denoting a hydrogen atom or a C1-C4 alkyl radical, optionally substituted with one or more hydroxyl groups; R2 represents a hydrocarbon-based radical containing from 1 to 18 carbon atoms; a homopolymer of a monomer comprising a sulfonic group; and a crosslinked acrylic acid homopolymer. Use for caring for and making up keratin materials.
US08883124B2 Use of fullerenes in photoacoustic imaging
Fullerenes, when irradiated with electromagnetic radiation, generate acoustic waves. A photoacoustic tomography method using a material comprising fullerenes is disclosed that includes irradiating the material with a radiation beam such as a laser. The resultant photoacoustic effect produced by the material is detected by at least one detector. A photoacoustic tomography system using a material comprising fullerenes is also described.
US08883122B2 Nanoparticle clusters formed from individual nanoparticles of two or more types
Nanoparticle clusters are described. In particular nanoparticle clusters formed from two or more individual nanoparticles of different types are described and methods for fabricating such nanoparticle clusters are further described. These nanoparticle clusters are fabricated by surface activating individual ones of the plurality of nanoparticles by desorption of surfactant molecules from the surface of the coated nanoparticles through exposure of the individual ones of the plurality of nanoparticles to an activating agent.
US08883120B2 Polypeptides having affinity for HER2
HER2 binding polypeptides comprising the amino acid sequence EX1 RNAYWEIA LLPNLTNQQK RAFIRKLYDD PSQSSELLX2E AKKLNDSQ wherein X1 in position 2 is M, I or L, and X2 in position 39 is S or C (SEQ ID NO:1) are disclosed. Moreover, such peptides comprising a chelating environment are disclosed. Also radiolabeled polypeptides formed by the peptides comprising a chelating environment and radionuclides are disclosed. Furthermore, methods of in vivo imaging of the body of a mammalian subject having or suspected of having a cancer characterized by overexpression of HER2 comprising administration of such a radiolabeled polypeptide followed by obtainment of an image of the body using a medical imaging instrument and also methods of treating such cancer are disclosed. Furthermore, the use of such a radiolabeled polypeptide in diagnosis and treatment of cancer characterized by overexpression of HER2. Nucleic acids encoding the polypeptides, expression vectors comprising the nucleic acids and host cells comprising the expression vectors are also disclosed.
US08883116B2 Alumina, luminophores and mixed compounds, and associated preparation processes
The present invention relates to the synthesis of luminophores and of reflective alumina for optimizing the emissive properties of a fluorescent layer.
US08883110B2 Synthetic amorphous silica powder and method for producing same
The synthetic amorphous silica powder of the present invention is characterized in that it comprises a synthetic amorphous silica powder obtained by applying a spheroidizing treatment to a granulated silica powder, and by subsequently cleaning and drying it so that the synthetic amorphous silica powder has an average particle diameter D50 of 10 to 2,000 μm; wherein the synthetic amorphous silica powder has: a quotient between 1.35 exclusive and 1.75 inclusive obtained by dividing a BET specific surface area of the powder by a theoretical specific surface area calculated from the average particle diameter D50; a real density of 2.10 to 2.20 g/cm3; an intra-particulate porosity of 0 to 0.05; a circularity between 0.50 inclusive and 0.75 inclusive; and a spheroidization ratio between 0.20 inclusive and 0.55 exclusive.
US08883109B2 High capacity stabilized complex hydrides for hydrogen storage
Complex hydrides based on Al(BH4)3 are stabilized by the presence of one or more additional metal elements or organic adducts to provide high capacity hydrogen storage material.
US08883108B2 Catalyst supports
This invention relates to a catalyst material, and its method of making and manufacture, useful for a diversity of chemical production processes as well as various emission control processes. More specifically, it relates to a catalyst composition, preferably comprising a metal oxide felt substrate, with one or more functional surface active constituents integrated on and/or in the substrate surface, which can be used in the removal of sulfur and sulfur compounds from hot gases as well as acting to trap solid particulates and trace metals within these hot gases.
US08883106B2 Method and a device for removing nitrogen oxides and sulphur trioxide from a process gas
A catalytic reactor (16) is provided for purposes of effecting therewith the removal of nitrogen oxides from a process gas (F) that includes at least two catalyst bed segments (48, 50, 52), each of which is provided with a closing device (60, 62, 64). The catalytic reactor (16) is operative for causing said process gas (F) to flow through a first catalyst bed segment (48). Said process gas (F) is at a first temperature at which the sulphur trioxide that is entrained in said hot process gas is at least partially precipitated out on to the catalytic material that said first catalyst bed segment (48) embodies. Periodically said closing device (60) is operated in order to thereby isolate said first bed segment (48) from the flow therethrough of said hot process gas (F). A regeneration system (34, 36, 38) is also provided that is operative for purposes of causing a regenerating gas to flow through the first bed segment (48). In addition, a sulphur trioxide removal device (20) is provided, which is separate from said catalytic reactor (16), and which is operative for purposes of effecting therewith the removal of the sulphur trioxide from said regenerating gas.
US08883100B2 Particle reduction with combined SCR and NH3 slip catalyst
The present invention relates to a particle filter comprising a porous carrier body, an SCR active component and an oxidation catalyst, wherein the SCR active component is present as coating on the exhaust-gas entry surface and the inner surface of the porous carrier body and the oxidation catalyst as coating on the exhaust-gas exit surface of the porous carrier body. According to the invention the oxidation catalyst changes its function depending on operating conditions. In normal operation it serves as NH3 slip catalyst for oxidizing excess NH3 and during filter regeneration it operates according to the 3-way principle for converting NOx and CO. The invention also relates to a method for producing the particle filter, the use of the particle filter for treating exhaust gases from the combustion of fossil, synthetic or biofuels as well as an exhaust-gas cleaning system which contains the particle filter according to the invention.
US08883097B2 Sulfidisation process and apparatus for enhanced recovery of oxidised and surface oxidised base and precious metal minerals
A method of treating value bearing material comprising oxidized or surface oxidized mineral values includes the steps of crushing the value bearing material, contacting the crushed material! with a sulfide solution to sulfide the oxidized or surface oxidized mineral values, and adding ions of a selected base metal to the crushed value bearing material. The value bearing material may comprise oxidized or surface oxidized base metal or precious metal minerals. The crushed value bearing material is prepared as a slurry or pulp comprising from 15% to 40% solids and the remainder comprising water. The sulfide solution preferably comprises a soluble sulfidiser such as sodium hydrosulfide and the base-metal ion solution preferably comprises metal salt of base metals like copper or iron. In a preferred embodiment of the method, the sulfide ion concentration in the slurry is measured with an ion-specific probe which measures the sulfide ion concentration as a potential, and the quantity of sulfidiser solution in the slurry is adjusted to maintain the measured sulfide ion concentration at or near the predetermined value. The invention extends to an installation for treating value bearing material according to the method.
US08883096B2 Extraction of uranium from wet-process phosphoric acid
In a preferred embodiment, a process for extracting uranium from wet-process phosphoric acid (WPA), comprises separating uranium from WPA to produce a loaded uranium solution stream and a uranium depleted WPA stream. The loaded uranium solution stream is then contacted by with an ion exchange resin. Uranium species bound to the ion exchange resin are eluted by contacting the resin with a solution comprising anions to produce a loaded uranium eluant stream. The loaded uranium eluant stream is treated to provide a uranium containing product.
US08883095B2 Analysis cartridge and analysis system thereof
An analysis cartridge and an analysis system thereof are disclosed. The analysis cartridge comprises a cartridge body, a liquid storage box and a sealing film. The cartridge body has an accommodation portion. The liquid storage box is disposed within the accommodation portion and has a liquid storage tank and a pillar receiving hole. The sealing film covers the pillar receiving hole and seals an opening of the liquid storage tank.
US08883091B2 Hydrodynamic focusing devices
A micro-fluidic device containing a micro-fluidic inlet channel to convey a process flow, a plurality of micro-fluidic focusing channels to each convey one of a plurality of focusing flows, a focusing manifold coupled with the inlet channel at an inlet port thereof and with the plurality of focusing channels at a plurality of focusing channel ports thereof to focus the process flow by contacting and hydrodynamically impacting at least three sides of the process flow with the focusing flows, and a micro-fluidic outlet channel coupled with the focusing manifold at an outlet channel port to convey the combined focused process flow and focusing flow from the focusing manifold.
US08883087B2 Biological sample measurement apparatus
A biological sample measurement apparatus includes container (10) having an opening in a top surface thereof and right and left accommodation chambers (12) and (13) formed by separating an inner space and the opening in container (10) by partition wall (11a), measurement device (1) accommodated in accommodation chamber (12) of container (10), and a holder accommodated in accommodation chamber (13) of container (10) and holding measurement device (1). Provided are recesses (15, 16) configuring holding means holding measurement device (1) on an outer peripheral wall configuring accommodation chamber (12) or in accommodation chamber (12) in a state where sensor mounting section (4) of measurement device (1) is projected to an outside of accommodation chamber (12).
US08883081B2 Ultraviolet germicidal irradiation system
A modular germicidal light grid system for use inside an air treatment apparatus that has a plenum in which a stream of air is enclosed. The system comprises at least one elongate member and at least one lamp assembly. Each lamp assembly comprises a housing defining at least one socket and is mounted to one elongate member at a predetermined position. The system further comprises at least one linear germicidal light source. Each light source has a longitudinal axis and a distal end constructed and arranged to mount within one socket of the housing. The elongate member is mounted within the plenum and the lamp assembly is mounted to the elongate member such that the longitudinal axis of the light source extends therein the stream of air and is positioned at an acute light angle relative to the direction of flow of the stream of air.
US08883080B2 Nano-enhanced evanescence integrated technique (NEET) based microphotonic device and sample analysis system
A device, a method of fabricating the device and a sample analysis system that includes the device are provided. The device includes an optical waveguide having a plurality of nanofeatures integrated thereon to influence at least one of evanescence and coupling of an optical field of the optical waveguide. The sample analysis system includes a fluidic actuation system for introducing sample specimen fluid into a microfluidic channel of the device for evanescence based detection.
US08883078B2 Sample testing system and transporting apparatus
A sample testing system comprising: a test unit for loading and testing a sample contained in the sample container accommodated in the rack; a rack storage for storing the rack accommodating the sample container from which the sample has been loaded into the test unit; and a transporting part, configured to transport the rack in a first direction and in a second direction that is a reverse direction of the first direction, for transporting the rack in the first direction to the rack storage and transporting the rack stored in the rack storage in the second direction to a sample loading position at which the sample is loaded from the rack into the test unit, is disclosed. A transporting apparatus is also disclosed.
US08883076B2 Apparatus and process for recycling absorbent sanitary products
An apparatus for treating used absorbent sanitary products, comprising, a rotary cylindrical autoclave having an inner surface and two ends, at least one of which terminates in a hatch that can be opened to enable access to said autoclave and sealably closed to enable pressurization of said autoclave; and a circuit for heating and pressurizing the autoclave for heating the absorbent sanitary products to a sterilization temperature, wherein said autoclave comprises a sealing layer on said inner surface, designed to prevent adhesion on said inner surface of material coming from destructuring of said absorbent sanitary products.
US08883075B2 Razor disinfection and storage device
An attractive and compact device and an effective method to store and disinfect a manual shaving razor are disclosed. The method reduces corrosion of the razor's metal blades. A compact container has separate but suitably connected chambers allowing for economy of use of as disinfectant liquid combining alcohol, detergent or soap and skin conditioner. By protecting the razor in one enclosed chamber, oxidative damage and rusting of blades is avoided. A knife edge element is placed at the bottom of another chamber to pierce the foil seal of a suitably inserted bottle within the other chamber. An optional third, drainage chamber below the other two chambers allows for appropriate drainage and removal both of excess fluid used, as well as hair and debris from the blades. The design of the device is compact and attractive, as is the method an extremely effective way of protecting and disinfecting the razor.
US08883067B2 Method for manufacture of tray
A method for manufacture of a resin tray is provided where a block mold is selected to be installed in a base mold according to the specification of the tray to be molded; a molding surface is composed of the upper surface of the block mold fixed to the base mold; thermoplastic resin material in the molten state is arranged opposite to the cavity; a step where thermoplastic resin material is molded by pushing it against the cavity; and as a result, recess part stored at a prescribed position.
US08883061B2 Cover assemblies for electrical cables and methods and kits including same
A method for forming a cover assembly on an electrical power transmission cable includes: mounting a tubular cover member around the cable such that a portion of the cover member defines a cavity surrounding the cable; providing a flowable electrical stress grading material in the cavity; and applying a vacuum to the cavity to evacuate air from the cavity and compact the electrical stress grading material in the cavity.
US08883060B2 Method for producing FRP cylinder and FRP cylinder
A method is provided for producing a weight-reduced FRP cylinder which can attain high strength, and also such an FRP cylinder is provided. This FRP cylinder producing method, in which a plurality of prepregs formed by impregnating reinforced fibers with thermosetting resin sheets are wound into a cylinder and thermally cured to be formed as a plurality of FRP layers, includes a simultaneous multilayer winding process in which a torsional rigidity retaining prepreg and a buckling prevention prepreg are continuously wound a plurality of turns with being layered on each other when the plurality of prepregs are wound into a cylinder, wherein the torsional rigidity retaining prepreg includes a layer of fibers oblique to a cylindrical axis direction of the FRP cylinder, and wherein the buckling prevention prepreg includes a layer of fibers orthogonal to the cylindrical axis direction.
US08883058B2 Method and apparatus for manufacturing waterproof footwear with attached compressible lining
A method and apparatus for making a lined waterproof footwear product, and footwear product formed therefrom, are provided. A last, having an exterior surface configured to correspond to the size and shape of the interior surface of the footwear product, is covered with a microcellular lining material. An injection mold comprises shells having a pre-determined configuration to mold an upper portion that attaches to the lining during the molding process. In the finished footwear product, the molded upper portion has a molded foot portion that extends around the wearer's foot and an upwardly-extending molded portion that covers a part of the lining while leaving another part of the lining uncovered.
US08883057B2 Non-ionomeric silane crosslinked polyolefin golf ball layers
The present invention relates to golf balls, and in particular, to golf balls having at least one portion formed from at least one non-ionomeric, silane-crosslinked polyolefin materials that are formed in the presence of moisture or water during golf ball construction. The present invention also relates to methods of forming golf balls having at least one portion formed from at least one non-ionomeric, silane-crosslinked polyolefin materials that are formed in the presence of moisture or water.
US08883055B2 Luminescent ceramic converter and method of making same
The present invention relates to a luminescent ceramic converter comprising a sintered, monolithic ceramic material that converts a light of a first wavelength to a light of a second wavelength, the ceramic material having substantially spherically shaped pores. The present invention also relates to methods for the manufacture of the luminescent ceramic converter that comprises the ceramic material having substantially spherically shaped pores.
US08883054B2 Mold monitoring
A monitor for maintaining a mold cycle count and other mold operation data and a corresponding system that generates a first remote record of the mold cycle data and a second remote record of the mold cycle data, the second remote record comprising a lesser, different and/or non-confidential version of the first remote record. The first remote record and the second remote record may then be coordinated among an OEM manufacturer, a moldmaker and a molder.
US08883053B2 Method for isolating flexible film from support substrate
Method for isolating a flexible film from a support substrate and method for fabricating an electronic device are provided. The method for isolating a flexible film from a support substrate includes providing a substrate with a top surface. A surface treatment is subjected to the top surface of the substrate, forming a top surface with detachment characteristics. A flexible film is formed on the top surface with detachment characteristics. The flexible film within the top surface with detachment characteristics is cut and isolated.
US08883050B2 Curable colored compositions, color filters and processes for preparing them, liquid crystal display devices, solid-state image sensors, and dye compounds
Provided is a curable colored composition, transmitting the light in the magenta region and absorbing the light in the cyan region. A curable colored composition comprising a metal complex in which a compound represented by formula (I) below is coordinated to a metal atom or a metal compound.
US08883047B2 Thermoelectric skutterudite compositions and methods for producing the same
Compositions related to skutterudite-based thermoelectric materials are disclosed. Such compositions can result in materials that have enhanced ZT values relative to one or more bulk materials from which the compositions are derived. Thermoelectric materials such as n-type and p-type skutterudites with high thermoelectric figures-of-merit can include materials with filler atoms and/or materials formed by compacting particles (e.g., nanoparticles) into a material with a plurality of grains each having a portion having a skutterudite-based structure. Methods of forming thermoelectric skutterudites, which can include the use of hot press processes to consolidate particles, are also disclosed. The particles to be consolidated can be derived from (e.g., grinded from), skutterudite-based bulk materials, elemental materials, other non-Skutterudite-based materials, or combinations of such materials.
US08883045B2 Metal nanowire-containing composition, and transparent conductor
The present invention provides a metal nanowire-containing composition containing at a least metal nanowire and a heterocyclic compound having an interaction potential of less than −1 mV.
US08883044B2 Multi-functional resin composite material and molded product using the same
Disclosed are a multi-functional resin composite material including (A) a thermoplastic resin, (B) a nickel-coated carbon fiber, (C) a carbon nanotube, and (D) an inorganic material having a volume resistance of about 10−3 Ω·m or less and a relative permeability of about 5000 or more, and a molded product fabricated using the same.
US08883043B2 Self-doped polyaniline nanoparticle dispersions based on boronic acid-phosphate complexation
Poly(anilineboronic acid)/phosphate nanoparticle dispersions are produced in high yields using the reactivity of the boronic acid moiety with phosphate in the presence of fluoride. The poly(anilineboronic acid)/phosphate dispersions have been characterized using spectroscopic, microscopic and electrochemical techniques. According to 11B NMR studies, the formation of anionic tetrahedral boronate group in phosphoric acid in the presence of fluoride forms the basis of self-doped, stabilized PABA nanoparticle dispersion. Transmission electron microscope images show that 25-50 nm diameter PABA nanoparticles are formed under these conditions. UV-vis, FT-IR-ATR spectroscopic and cyclic voltammetric results confirm the formation of the conducting form of PABA. Films produced from these particles exhibit enhanced redox stability and potential dependant conductivity under neutral and basic pH conditions due to the formation of a boron-phosphate complex containing fluoride, which results in a self-doped form of the polymer.
US08883042B2 Production of graphene sheets and features via laser processing of graphite oxide/ graphene oxide
Graphene production using a continuous or pulsed laser beam focused on a substrate of graphite oxide in a significantly inert environment is disclosed. Laser-induced graphene features are characterized by a 2D-band in the Raman spectra. When the photons of the laser at a various frequencies and power levels beam impinge a graphite oxide foil for various amounts of time, a strip, divet, trench, or hole, having graphene at the bottom or sides is produced. The concentration of the graphite oxide and the laser beam may be adjusted so that the depth of the trench created is a certain depth less than the thickness of the foil. Additionally, in some embodiments, the evaporation of the water during the Hummers method is adjusted so that there remains interlaminar water in the graphite oxide foil. The presently disclosed subject matter may also be used in patterning using rastering or substrate motion.
US08883041B2 Method for preparing phosphor
A method for preparing a phosphor that comprises a crystalline oxide having M1O3 (M1 is a tetravalent metallic element) as a main framework thereof and essentially including a halogen element X (X is at least one element selected from a group consisting of F, Cl, Br, and I) and divalent metal ions M2 and Eu2+, includes using a compound represented by a compositional formula NH4X as a starting material when synthesizing the phosphor. At least a compound represented by a compositional formula NH4Cl may be used as the starting material.
US08883040B2 Luminescent material
A luminescent material is disclosed. The luminescent material may include a first compound having a host lattice comprising first ions and oxygen. A first portion of the first ions may be substituted by copper ions. In one embodiment, the host lattice may include silicon, the copper ions may be divalent copper ions and the first compound may have an Olivine crystal structure, β-K2SO4 crystal structure, a trigonal Glaserite (K3Na(SO4)2) or monoclinic Merwinite crystal structure, a tetragonal Ackermanite crystal structure, a tetragonal crystal structure or an orthorhombic crystal structure. In another embodiment, the copper ions do not act as luminescent ions upon excitation with the ultraviolet or visible light.
US08883038B2 Syntheses of ultra-bright fluorescent silica particles
The object of the invention is to producing ultras bright fluorescent silica particles by synthesizing large nanopore silica particles with self sealed channels/pores and then stopping the synthesizing before large nanopore silica particles have been formed, wherein said sintering solution has produced nanoparticles. The large nanopore silica particles are micron size. The synthesizing is stopped by diluting said synthesizing solution with a neutralizing medium such as an aqueous solution of definite acidity of pH7 and higher an exemplary value of pH11 (sodium hydroxide). The time range for stopping the synthesizing ranges from tens of seconds to ten of minutes.
US08883036B2 Hydrogen sulfide stream for catalyst sulfidation from refinery rich amines
A process for the production of a H2S-enriched H2 gas stream without the need for H2S compression is disclosed. A slip stream of rich amine from a hydroprocessing unit is reduced in pressure and stripped with a hydrogen-containing gas. The H2S content of the resulting gas stream can be readily controlled by adjusting the stripping pressure and/or hydrogen rate. The H2S-enriched H2 gas stream is suitable for the sulfidation of catalytically active metals.
US08883035B2 Formulation of a ware washing solid controlling hardness
A water hardness controlling agent includes a polyacrylic acid or salt thereof having a molecular weight of between about 1,000 and about 50,000 g/mol, an acrylic-maleic acid copolymer or salt thereof having a molecular weight of between about 1,000 and about 100,000 g/mol and a phosphonocarboxylic acid or salt thereof. A ratio of acrylic-maleic acid copolymer or salt thereof to polyacrylic acid or salt thereof to phosphonocarboxylic acid or salt thereof in parts per million is about 1-30:10-80:6-20.
US08883026B2 Substrate processing method and substrate processing apparatus
A substrate processing method includes a water removing step of removing water from a substrate, a silylating step of supplying a silylating agent to the substrate after the water removing step, and an etching step of supplying an etching agent to the substrate after the silylating step. The substrate may have a surface on which a nitride film and an oxide film are exposed and in this case, the etching step may be a selective etching step of selectively etching the nitride film by the etching agent. The etching agent may be supplied in a form of a vapor having an etching component.
US08883025B2 Plasma processing apparatus and plasma processing method
A plasma processing apparatus includes a stock unit, a processing unit, and an alignment chamber. The stock unit supplies and collects a conveyable tray formed with a plurality of housing holes in each of which a wafer is housed. In the processing chamber, plasma processing is executed on the wafers housed in the tray supplied from the stock unit. The alignment chamber is provided with a rotating table on which the tray before being subjected to the plasma processing is set to perform positioning of the wafers on the rotating table. A housing state determination unit of a control device determines whether or not the wafer is misaligned with respect the housing hole of the tray based on a height detected by height detecting sensors.
US08883023B2 Method for forming pattern
A method for forming a pattern includes providing a composition to form a resist underlayer film on a surface of a substrate to be processed. The composition contains a calixarene based compound having a group represented by a following formula (i) bound to at least a part of an aromatic ring or at least a part of a heteroaromatic ring of the calixarene based compound. The resist underlayer film on the surface of the substrate is treated with heat or an acid. A resist pattern is formed on a surface of the resist underlayer film. The resist underlayer film and the substrate are etched using the resist pattern as a mask to form the pattern on the substrate. The dry-etched resist underlayer film is removed from the substrate with a basic solution. —O—R1  (i)
US08883015B2 Patch production
A method of producing projections on a patch including providing a mask on a substrate and etching the substrate using an etchant and a passivant to thereby control the etching process and form the projections, wherein the passivant does not include oxygen.
US08883014B2 Monolithically formed EWOD device and method of making the same
A monolithic fabrication method of parallel-plate electrowetting-on-dielectric (EWOD) chips for digital microfluidics of picoliter droplets is disclosed. Instead of assembling a second substrate to form a top plate, the top plate is generated in situ as a thin-film membrane that forms a monolithic cavity having a gap height on the order of micrometers with excellent accuracy and uniformity. The membrane is embedded with EWOD driving electrodes and confines droplets against the device substrate to perform digital microfluidic operations. Two main attributes of the monolithic architecture that distinguish it from tradition methods are: (i) it enables excellent control of droplet dimensions down to the micrometer scale, and (ii) it does not require the typical alignment and assembly steps of the two plates.
US08883011B2 Production of monolithic separating columns
The present invention relates to a process for the production of monolithic separating columns using monolithic moldings whose diameter is reduced by grinding, and to separating columns having improved separation efficiency produced in this way, and to the use thereof.
US08883008B2 Double fiber bundle dialyzer
A dialyzer composed of: first and second dialyzation chambers, and an intermediate chamber interposed between the first and second dialyzation chambers. Each dialyzation chamber has opposed first and second ends and contains a filter member that separates the chamber into a blood compartment and a dialysate compartment. Each of the compartments extends between first and second ends. Each of the chambers has a respective one of a blood inlet or outlet and a dialysate inlet or outlet arranged so that blood and dialysate flow in counter-current to one another in both chambers. The intermediate chamber is connected to form a dialysate-free blood flow passage between the blood compartments.
US08883007B2 Fluid separation system with reduced fouling
A fluid separation system includes a separation membrane having a pattern of features thereon.
US08883003B2 Device for filtration with a set of least one filter cassette
The invention concerns a filtration device comprising a manifold (3) providing fluid connection and mechanical connection comprising a clamping plate (4) movably mounted relative to the manifold (3) and adapted to compress at least one cassette (2) against the manifold (3), means for driving and guiding the clamping plate comprising a rod (6) extending between the manifold (3) and the plate (4), an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold (3), and the member carrying the rod (6) and driving the plate (4) via the rod (6) to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.
US08883002B2 Separating agent for optical isomers and separation column for optical isomers
This invention provides a separating agent for optical isomers, which has high asymmetry recognition ability and can be used particularly at a high flow rate when used for the separation of the optical isomers, and a separation column for optical isomers having the same. This invention provides: a separating agent for optical isomers which is used for separation of optical isomers in a sample comprising the optical isomers, which is comprising a monolithic inorganic type carrier having a meso pore formed on an inner wall surface of a specific macropore, and a polysaccharide or a polysaccharide derivative supported on the monolithic inorganic type carrier, wherein the meso pore has a pore size of 6 to 100 nm; and a separation column for optical isomers in which the separating agent for optical isomers is held in a column tube.
US08883000B2 Water purification apparatus and method
A water purification apparatus comprising at least: (a) one or more water purification components to provide a purified water stream, preferably having a conductivity of less than 1 μS/cm; and (b) a stepper motor (35) to control the dispense of the purified water stream (28) from the water purification apparatus. Stepper motors can provide very fine and accurate control of the dispense of the purified water stream from the water purification apparatus, which control is unaffected by the flow or flow rate of the purified water stream.
US08882997B2 Wastewater treatment method and apparatus
The present invention discloses a method and apparatus for separating particles and dissolved matter from a produced water fluid stream. Specifically, the present invention includes a first pressure source which transports untreated produced water or contaminated aqueous fluid into a separator annulus with a filter element disposed therein. The untreated fluid is placed under appropriate pressure sufficient to produce turbulent flow, increased particle kinetics and/or cavitation allowing the desired fluid to penetrate and pass into and through the, filter media. The treated fluid is then transported to a collection tank. The contaminant matter retained by the filter media may be removed by the nearly instantaneous reverse pressurization of the separator annulus by a second pressure source thereby removing the contaminant particles away from contact with the filter media, and which may then be transported to a waste collection tank or a separator for further treatment.
US08882993B2 Stabilized aggregates of small crystallites of zeolite Y
This invention relates to stabilized aggregates of small primary crystallites of zeolite Y that are clustered into larger secondary particles. At least 80% of the secondary particles may comprise at least 5 primary crystallites. The size of the primary crystallites may be at most about 0.5 micron, or at most about 0.3 micron, and the size of the secondary particles may be at least about 0.8 micron, or at least about 1.0 μm. The silica to alumina ratio of the resulting stabilized aggregated Y zeolite may be 4:1 or more.
US08882984B2 Process for preparing diaryl carbonate
A process for preparing diaryl carbonate and utilizing at least part of the process wastewater by increasing the concentration of the wastewater phases containing sodium chloride for the electrolysis by means of osmotic membrane distillation with simultaneous dilution of the sodium hydroxide solution obtained from the electrolysis for the diaryl carbonate production process (diphenyl carbonate process) is described.
US08882980B2 Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
Devices and methods for detecting an analyte are provided. Devices for voltage sensing of analytes may comprise a fluidic channel defined in a substrate, a pair of sensing electrodes disposed in a fluidic channel for sensing voltage therein, and a pair of electromotive electrodes for applying potential along the fluidic channel. The pair of sensing electrodes may include a first and second sensing electrode disposed at two discrete locations along the length of the fluidic channel and the pair of electromotive electrodes may be disposed at a first end and a second end of the fluidic channel. The fluidic channel may include a nanochannel or a microchannel. Methods for detecting an analyte may include the steps of disposing the analyte in a fluidic channel; applying a potential along the fluidic channel to generate an electrophoretic force therein such that the analyte is translocated from a first end of the fluidic channel to a second end of the fluidic channel; and measuring a voltage signal between a pair of sensing electrodes disposed in the fluidic channel as the analyte moves past the sensing electrodes.
US08882976B2 Magnetron unit moving apparatus for preventing magnetization and magnetron sputtering equipment having the same
A magnetron unit moving apparatus for preventing magnetization and magnetron sputtering equipment having the same. The magnetron unit moving apparatus includes a magnetron unit disposed adjacent to a target, to generate a specific magnetic field, and a movement unit to space the magnetron unit and the target apart such that a strength of a magnetic field generated over the target is within a predetermined reference strength range. It is possible to space the target and the magnetron unit apart so as to prevent the target from being magnetized when a process is not performed.
US08882974B2 Support mechanism
A support mechanism used in an electro plasma polishing process includes a support beam, a first electrically conducting assembly, and a second electrically conducting assembly. The first electrically conducting assembly and the second electrically conducting assembly are mounted on the support beam. The first electrically conducting assembly is electrically insulated from the second electrically conducting assembly.
US08882969B2 In-line treatment of hydrocarbon fluids with ozone
A system for treating recovered fluids in-line that includes a thermal reactor for separating contaminated drill cuttings into drill cuttings and contaminants by applying heat to the contaminated drill cuttings so as to vaporize contaminants from the contaminated drill cuttings; a first condenser in fluid connection with the thermal reactor for condensing the vaporized contaminants; a separator in fluid connection with the first condenser for separating the condensed vapors into an oleaginous liquid and an aqueous liquid, wherein at least a portion of one of the aqueous liquid and oleaginous liquid is fed back into the first condenser via a feedback line; and an ozone generator operatively coupled to the feedback line, wherein at least the portion of the fed back liquid is ozonated by the ozone generator and fed into the condenser is disclosed.
US08882967B1 Systems and methods for purifying process water
Disclosed are methods for purifying a process water, which can comprise providing a process water comprising a first concentration of a first dissolved gas and a first concentration of a first dissolved ion, filtering the process water to create a filtered process water comprising a second concentration of the first dissolved gas, and evaporating the filtered process water to create a water vapor comprising a second concentration of the first dissolved ion that is less than the first concentration of the first dissolved ion.
US08882966B2 Pyrolytic reactor
A pyrolytic reactor, comprising an inner drum having a circumferential wall formed with a plurality of apertures, an outer drum surrounding the inner drum and defining a clearance therebetween, a feeding device for feeding a plurality of feedstock pieces to the interior of the inner drum, an inlet port through which heat carrier gases flow and are directed to said clearance, for introduction of the heat carrier gases via said plurality of apertures to the inner drum interior and causing pyrolysis of the fed feedstock pieces, a conveyor for transporting a plurality of solid residue pieces produced from a pyrolytic process, and an outlet port through which product vapors and gases, heat depleted heat carrier gases, and the plurality of solid residue pieces are discharged.
US08882962B2 Plasma processing apparatus
Provided is a plasma processing apparatus wherein an electrode embedded in a mounting table is supplied with high frequency power for biasing. A surface, which is exposed to plasma and is of an aluminum cover functioning as an opposite electrode to the electrode of the mounting table, is coated with a protection film, preferably a Y2O3 film. A second portion forming an upper side portion of the processing chamber and a first portion forming a lower side portion of the processing container are provided with an insulating upper liner and an insulating lower liner thicker than the upper liner, respectively. Thus, undesirable short-circuits and abnormal electrical discharge are prevented and stable high-frequency current path is formed.
US08882961B2 Substrate treatment apparatus
The density of a treatment fluid in exhaust gas is reduced, the amount of the treatment fluid that flows into exhausting equipment connected to a substrate treatment apparatus is reduced, and a load on the exhausting equipment is reduced. A substrate treatment apparatus includes: a substrate treating unit that treats a substrate; a treatment fluid supply unit that supplies, to the substrate treating unit, a treatment fluid used to treat the substrate; and an exhaust gas treating unit into which an exhaust gas containing the treatment fluid discharged from the substrate treating unit is introduced. The exhaust gas treating unit includes spray nozzles that spray a solvent toward the exhaust gas, the solvent dissolving the treatment fluid, thereby reducing the density of the treatment fluid in the exhaust gas. The exhaust gas treating unit has porous dispersion plates that cause the exhaust gas to disperse.
US08882955B2 Automated labeling method and label supply therefor
An automated labeling method and label supply therefor. The method and label supply are particularly adapted for labeling produce, and more particularly fruit, in high volumes at high speed.
US08882941B2 Mechanism of structural formation for metallic glass based composites with enhanced ductility
An aspect of the present disclosure relates to an alloy composition, which may include 52 atomic percent to 68 atomic percent iron, 13 to 21 atomic percent nickel, 2 to 12 atomic percent cobalt, 10 to 19 atomic percent boron, optionally 1 to 5 atomic percent carbon, and optionally 0.3 to 16 atomic percent silicon. The alloy may include 5 to 95% by volume of one or more spinodal microconstituents, wherein the microconstituents exhibit a length scale less than 50 nm in a glass matrix.
US08882940B2 Bulk solidifying amorphous alloys with improved mechanical properties
Bulk solidifying amorphous alloys exhibiting improved processing and mechanical properties and methods of forming these alloys are provided. The bulk solidifying amorphous alloys are composed to have high Poisson's ratio values. Exemplary Pt-based bulk solidifying amorphous alloys having such high Poisson's ratio values are also described. The Pt-based alloys are based on Pt—Ni—Co—Cu—P alloys, and the mechanical properties of one exemplary alloy having a composition of substantially Pt57.5Cu14.7Ni5.3P22.5 are also described.
US08882939B2 Zirconium alloy resistant to corrosion in drop shadows for a fuel assembly component for a boiling water reactor, component produced using said alloy, fuel assembly, and use of same
A zirconium alloy that is resistant to shadow corrosion for a boiling water nuclear reactor fuel assembly component, the alloy being characterized in that: its composition in percentages by weight is as follows: Nb=0.4%-4.5% Sn=0.20%-1.7% Fe=0.05%-0.45% Fe+Cr+Ni+V=0.05%-0.45%, with Nb≦9×[0.5−(Fe+Cr+V+Ni)] S=traces-400 ppm C=traces-200 ppm Si=traces-120 ppm O=600 ppm-1800 ppm the balance being Zr and impurities from processing; in that, during fabrication, after its last hot deformation, it is subjected to one or more heat treatments lying in the range 450° C. to 610° C. for a total duration of at least 4 h, with at least one cold rolling operation with a rolling ratio of at least 25%; and in that a final heat treatment operation is performed at a temperature in the range 450° C. to 610° C. for 1 minute to 20 hours. A fuel assembly component made of the alloy, a fuel assembly including the component, and the use thereof.
US08882934B2 Solder powder, and solder paste using solder powder
In solder powder having an average particle size of 5 μm or less and constituted by a center core and a covering layer covering the center core, wherein the center core consists of an intermetallic compound of silver and tin, or silver and the intermetallic compound of silver and tin, the covering layer consists of tin, and an intermediate layer which consists of an intermetallic compound of copper and tin is interposed between the center core and the covering layer so that at least a part of the center core is covered thereby.
US08882933B2 Dishwasher having a device for opening the door in gaps
A dishwasher includes a washing tub, a latch keeper disposed on the washing tub and mounted on a push rod, and a pivotable door configured to close the washing tub. The door includes a latching mechanism configured to engage the latch keeper in accordance with a closing of the door. An actuator is configured to move the push rod in an opening direction so as to open the door to an ajar position. A return device is configured to return the latch keeper in a direction opposite to the opening direction approximately at least to an initial position upon a further opening of the door.
US08882930B2 Method for processing process-target object
Provided is a method including the steps of: carrying out a storage process by causing a processing jig, which has a supply opening for supplying a first processing liquid, to be positioned such that a storage space section into which the supply opening is open is sandwiched by the processing jig and the process-target surface, and by storing the first processing liquid in the storage space section; and carrying out a rotation process by supplying the first processing liquid onto the process-target surface from the supply opening, while supplying a second processing liquid onto the outer peripheral part, in a state where the process-target object is being rotated, in the step for carrying out the rotation process, the processing jig being moved along a direction which is not a direction along which the process-target object is being rotated.
US08882923B2 Substrate processing apparatus and method of manufacturing semiconductor device
A substrate processing apparatus includes: a process chamber having an object to be heated therein and configured to process a plurality of substrates; a substrate holder configured to hold the substrates with an interval therebetween in a vertical direction in the process chamber; a first heat exchange unit supporting the substrate holder from a lower side thereof in the process chamber and configured to perform a heat exchange with a gas in the process chamber; a second heat exchange unit provided in the process chamber, the second heat exchange unit being horizontally spaced apart from the first heat exchange unit with a gap therebetween and being configured to perform a heat exchange with the gas in the process chamber; and an induction heating unit configured to subject the object to be heated to an induction heating from an outer side of the object to be heated.
US08882918B2 Vapor deposition apparatus
A vapor deposition apparatus (50) includes: a mask unit (54) including a vapor deposition source (70), a vapor deposition mask (60), and a mask holding member (80); a substrate holder (52); and at least either a mask unit moving mechanism (55) or a substrate moving mechanism (53), with a roller (83) provided in a surface of one of (A) the substrate holder (52) and (B) the mask holding member (80) which faces the other one of (A) the substrate holder (52) and (B) the mask holding member (80).
US08882916B2 Film deposition apparatus, film deposition method, and computer readable storage medium
In an disclosed film deposition method, after a film deposition-alteration step is carried out that includes a film deposition process where a Si containing gas is adsorbed on a wafer W and the adsorbed Si containing gas on the wafer is oxidized by supplying an O3 gas to the upper surface of the wafer, thereby producing a silicon oxide layer(s) by rotating a turntable on which the wafer is placed, and an alteration process where the silicon oxide layers) is altered by plasma, an alteration step where the silicon oxide layer(s) is altered by plasma while the Si containing gas is not supplied.
US08882913B2 Apparatus of chemical vapor deposition with a showerhead regulating injection velocity of reactive gases positively and method thereof
The present invention is related to an apparatus and a method for chemical vapor deposition (CVD) using a showerhead through which a reactive gas of at least one kind and a purge gas is injected over a substrate on which a film is growing. A plural number of reactive gas showerhead modules are laid on a purge gas showerhead module. Each reactive gas is injected from a bottom of the showerhead after flowing through the showerhead as separated, thereby preventing the reactive gases from causing homogeneous gas phase reactions and from generating unwanted particles at the inside of the showerhead. And a purge gas is injected from the bottom surface of the showerhead by forming a protective curtain, thereby suppressing diffusion of the reactive gas injected backwardly. Each reactive gas is mixed with an injection support gas which is a kind of inert gas in a mixing zone at inside of the showerhead, where the injection velocity of each reactive gas is regulated positively by the amount of the injection support gas mixed. The present invention further includes an apparatus and a method, wherein the showerhead is cooled by a cooling jacket which keeps the temperature of the showerhead at proper levels to prevent both the condensation and the thermal decomposition of the reactive gas used.
US08882911B2 Apparatus for manufacturing silicon carbide single crystal
An apparatus for manufacturing a silicon carbide single crystal grows the silicon carbide single crystal on a seed crystal by supplying a material gas from below the seed crystal. The apparatus includes a heating container and a base located in the heating container. The seed crystal is mounded on the base. The apparatus further includes a first inlet for causing a purge gas to flow along an inner wall surface of the heating container, a purge gas source for supplying the purge gas to the first inlet, a second inlet for causing the purge gas to flow along an outer wall surface of the base, and a mechanism for supporting the base and for supplying the purge gas to the base from below the base.
US08882906B2 Method for recycling waste water from a stainless steel slag treatment process
The present invention relates to a method for recycling waste water from a stainless steel slag treatment process wherein stainless steel slag is brought into contact with water, in particular to neutralize the free lime contained therein, thereby producing said waste water. This waste water contains heavy metals, including at least chromium, and has a pH higher than or equal to 11. In accordance with the invention, it is used as production water for manufacturing mortar and/or concrete. In this way, the heavy metals, which are dissolved in the waste water and thus readily available, become bound in the newly formed cement phases so that they are prevented from leaching. Moreover, it has been found that the workability of the fresh mortar or concrete and also the quality of the final mortar or concrete materials is not negatively affected by the use of this alkaline waste water and that an accelerated setting could be achieved during the first hours.
US08882905B1 Recycled compositions for construction, and methods of utilizing and producing the same
A low density annular grout composition for filling voids. The composition may consist of cementitious fly ash, water, set retarder and cellular foam. The composition may have a compressive strength of between 100 and 600 psi at seven days and less than 1500 psi at 28 days. The composition may have a density between 20 and 75 pcf. Also disclosed is a method of filling a void with a low density annular grout composition. The method can include determining the time necessary to fill the void, adding water and set retarder to a cementitious fly ash to make a wet mixture, adding air to the wet mixture, and adding the composition to the void.
US08882903B2 Aluminium phosphate dihydrate as white pigment in paints
The present invention provides white pigments of crystalline aluminum orthophosphate dihydrate, their use as white pigment in paints and also processes for their production.
US08882900B2 Spin finish for elastomer fibers
Spin finish having solid microparticles of a specified kind dispersed colloidally at a specified ratio in a dispersoid of a specified kind containing a smoothing agent component of a specified kind and a nitrogen-containing compound of a specified kind at specified ratios is for elastomer fibers such that packages having superior roll shape and unwinding property can be obtained in the production and fabrication process.
US08882898B2 Emulsified release agent for composite panel
The present invention is directed to an emulsified release agent for use in manufacturing of wood products from wood fibers or chips with pMDI adhesives, where the application process for the release agent would normally agitate the release agent. The emulsified release agent is simple to manufacture, has good stability and storage, provides effective release between the wood product and the metal surfaces, allows for production of wood products from wood fibers or chips at high temperature, without causing excessive press buildup and improves the physical properties of the wood product and shortens press time. The emulsified release agent composition for use with a pMDI adhesive comprises an emulsified mixture of: (a) an alkali metal salt of a fatty acid having 8-18 carbon atoms, and (b) an alkali metal salt of a phosphate ester having 6-22 carbon atoms and having an HLB number of 4 or less.
US08882897B2 Phase change inks comprising aromatic diester crystalline compounds
A phase change ink composition suitable for high speed ink jet printing, including printing on coated paper substrates. In particular, the phase change ink composition comprises an aromatic diester crystalline compound and an amorphous compound, and optionally, a colorant, which provides for a robust ink.
US08882892B2 Powder coating system having powder recovery cyclone with hinged lower section
A cyclone comprises a second or lower portion that is pivotable with respect to a first or upper portion about an articulation between a first position and a second position; the second portion being aligned with the first portion along a first or vertical axis when the second portion is in the first position, and the second portion being aligned on a second axis that is different from the first axis when the second portion is moved from the first position to the second position. In various additional embodiments, the second axis may be normal to the first axis, for example, in the first position the lower portion is horizontal and in the first position the lower portion is vertical and aligned with the upper portion. The second position may be used as a cleaning position. When the lower portion is pivoted away from the upper portion, the vortex is interrupted. In the second position, the lower portion may also interface with a suction mechanism.
US08882890B2 Apparatuses and methods for separating liquefiable hydrocarbons from hydrogen-, hydrocarbon-containing gas streams
Embodiments of apparatuses and methods for separating liquefiable hydrocarbons from H2-, hydrocarbon-containing gas streams are provided. In one example, a method comprises positioning a H2-, hydrocarbon-containing gas stream in an internal volume of a vessel below a heat exchange absorption section. A hydrocarbon-containing liquid stream is positioned in the internal volume above the heat exchange absorption section. The hydrocarbon-containing liquid stream is countercurrent contacted with at least a portion of the H2-, hydrocarbon-containing gas stream along a tube portion of the heat exchange absorption section to separate H2 and C3+ hydrocarbons. The hydrocarbon-containing liquid stream and the at least the portion of the H2-, hydrocarbon-containing gas stream are cooled along the tube portion to facilitate separating H2 and C3+ hydrocarbons.
US08882889B2 Recovery of Xe and other high value compounds
A system and method for recovering high value gas from a process stream, material or environment containing same, e.g., xenon by contacting gas from the process stream, material or environment with a carbon adsorbent effective to sorptively capture same, free of or with reduced concentration of fluid species present with the high value gas in the high value gas-containing gas in the process stream, material or environment. Other aspects of the disclosure include a radon detection method and product.
US08882888B2 Water recovery system and method
A system and method recover water from an ambient airstream. Dehumidification of the airstream is also achieved by removal of the water. A device of the system includes a chamber having a group of trays that hold respective amounts of liquid desiccant in each tray. A foam media absorbs the desiccant to increase an exposed surface of the desiccant to the airstream. Fans and valves are used to control airflow through the device. A charge cycle circulates air through the device to remove water vapor from the airstream. A subsequent extraction cycle removes water collected in the liquid desiccant by a condenser communicating with the chamber. An integral heat exchanger adds heat to the chamber during the extraction cycle. A controller is used to integrate and manage all system functions and input variables to achieve a high efficiency of operational energy use for water collection.
US08882885B2 System to remove dissolved gases selectively from liquids
A system to purge dissolved gases selectively from liquids can include a first contactor having two first contactor inlets and two first contactor outlets. The first contactor can receive liquid from a liquid source at a first inlet of the first contactor and an inert gas source at a second inlet of the first contactor, the inert gas can purge a first portion of gas from the liquid source. The first portion of purged gas exits the first contactor at a first outlet of the first contactor. The second contactor can receive input from the second outlet of the first contactor and the inert gas, the inert gas purges a second portion of the gas from the liquid source. The second portion of purged gas can exit the second contactor at a first outlet of the second contactor.
US08882883B2 Apparatus and methods to monitor and control cyclic process units in a steady plant environment
Apparatus and methods are disclosed that allow for the monitoring and analysis of production process data for a multi-step asynchronous cyclic production process (e.g. pressure swing adsorption) in a steady state plant (such as a steam methane reforming plant). Data collected from cooperating sensors is processed applying a moving window discrete Fourier transform (DFT). The transformed data can be further analyzed in the broader steady-state plant environment to accurately detect any process anomalies and avoid false alarms.
US08882882B2 Method of manufacturing Fe and Ni containing material and cobalt containing material using recycling residue of spent catalyst and method of manufacturing raw material for stainless using the Fe and Ni containing material and method of manufacturing Fe-Ni alloy
Methods of manufacturing Fe and Ni-containing material and Co-containing material from petrochemical desulfurization residue containing Fe and Ni or Fe and Co, manufacturing raw material for stainless steel using the Fe and Ni-containing material, and manufacturing ferro-nickel using the Fe and Ni-containing material. The method of manufacturing Ni and Fe-containing material includes acid-treating Ni and Fe-containing residue to remove alkali therefrom; drying the residue and heat treating the residue in a temperature range from 600° C. (degree Centigrade) to 1300° C. (degree Centigrade) in a reducing atmosphere to reduce Ni and Fe oxides in the residue into metal state; leaching a resultant product obtained by the reduction using acid to selectively dissolve Ni and Fe; filtering the acid leached product to obtain a solution containing Ni and Fe ions; neutralizing the solution containing Ni and Fe ions using alkali to produce Fe,Ni hydroxide; and filtering and drying a resultant product obtained by the neutralization.
US08882880B2 Method for controlling extremely low Ti in extra low carbon AlSi-killed steel
The present invention provides a method for controlling extremely low Ti in extra low carbon AlSi-killed steel, the weight percentage of the chemical composition of the extra low carbon AlSi-killed steel comprising: C≦0.005%, Si: 0.1-3.4%, Mn: 0.1-0.5%, P≦0.2%, S≦0.002%, Al: 0-1.2%, N≦0.005%, Ti≦0.0015 and a balance substantially being Fe and inevitable impurities; the liquid steel having said chemical composition is obtained by hot metal preprocessing, smelting, retained RH smelting and ingoting, wherein the top ladle slag is modified, and calcium-aluminum based modifier of 0.6-1.7 kg/t steel are added, so as to ensure a controlling demand that when refined RH decarburization is over, the content of T.Fe in top ladle slag composition ≧5%, the content of Al2O3≦23%; when refined RH decarburization is over, ferrosilicon, ferroaluminum or ferromanganese is employed to perform deoxide and alloying, then perform a deep desulfurization, and desulfurizing efficiency is 50% to 70%.
US08882879B2 Method for preparing nano silver particles
The invention provides a method for preparing nano silver particles comprising mixing polyvinyl pyrrolidone (PVP) and silver nitrate (AgNO3) in a solvent to form a reactive solution, heating the reactive solution to a temperature less than the boiling point of the solvent for the formation reaction of nano silver particles, adding an accelerating agent into the reactive solution during the formation reaction of the nano silver particles, and terminating the formation reaction when the size of the nano silver particles formed in the reaction solution reaches about 50 nm to 120 nm in diameter.
US08882878B2 Method of producing ultra-fine metal particles
A method of producing ultra-fine metal particles of the present invention includes: blowing metal powders of raw materials into reducing flame formed by a burner 3 in a furnace 5, wherein the metal powders are melted in the flame and allowed to be in an evaporated state, to thereby obtain the spherical ultra-fine metal particles. In the present invention, the atmosphere in the furnace 5 is preferably prepared such that the CO/CO2 ratio is within a range from 0.15 to 1.2. Also, a spiral flow-forming gas is preferably blown into the furnace 5, and the oxygen ratio of the burner 3 is preferably within a range from 0.4 to 0.8. As raw materials, a metal oxide and/or a metal hydroxide which contain the same metal as the metal powders may be used together with the metal powders.
US08882876B2 Fiber webs including synthetic fibers
Filter media suitable for various applications and related components, systems, and methods associated therewith are described. The filter media may include a fiber web having a mixture comprising non-fibrillated synthetic fibers and fibrillated fibers, such as lyocell. The fiber web may also include multi-component fibers (e.g., bi-component fibers). In some embodiments, glass fibers are not incorporated into the fiber web.
US08882875B2 Waved filter media and elements
Various high performance, high efficiency filter media are provided that are cost effective and easy to manufacture. In particular, various filter media are provided having at least one layer with a waved configuration that results in an increased surface area, thereby enhancing various properties of the filter media. The filter media can be used to form a variety of filter elements for use in various applications.
US08882873B2 Vortex finder for cyclone separator
A vortex finder for a cyclone separator, comprising a plurality of superposed rings each including a plurality of suspended plate segments. Each of the plate segments includes a main plate having radially offset upper and lower end portions, opposite inner and outer faces, an upper support member integrally formed with the upper end portion to protrude from the outer face, and a lower support member integrally formed with the lower end portion to protrude from the inner face. The upper support member of the plate segments of the one of the rings engages and is supported by the lower support member of the plate segments of another of the rings positioned above the one of the rings. The lower support member defines an open-bottom pocket having at least one pass-through opening for fluidly connecting a space inside the vortex finder with a space outside the vortex finder.
US08882872B2 Graphite coated metal nanoparticles for polycrystalline diamond compact synthesis
A method of forming polycrystalline diamond includes forming metal nanoparticles having a carbon coating from an organometallic material; combining a diamond material with the metal nanoparticles having the carbon coating; and processing the diamond material and the metal nanoparticles having the carbon coating to form the polycrystalline diamond. Processing includes catalyzing formation of the polycrystalline diamond by the metal nanoparticles; and forming interparticle bonds that bridge the diamond material by carbon from the carbon coating.
US08882871B2 Alumina sintered body, abrasive grains, and grindstone
Provided are an alumina sintered compact containing a titanium compound and an iron compound, wherein FeTiAlO5 grains exist in the grain boundary of the alumina grains and the mean grain size of the FeTiAlO5 grains is from 3.4 to 7.0 μm; and an abrasive grain and a grain stone using the alumina sintered compact.
US08882867B2 Gasification reactor with double wall cooling
It is supposed to be possible to achieve an essentially uniform water film protecting the corresponding metal panels, in a gasification reactor for producing crude gas containing CO or H2, by gasification of ash-containing fuel with oxygen-containing gas, at temperatures above the melting temperature of the ash, wherein a reaction chamber formed by a membrane wall through which cooling medium flows, a transition area as well as a quench chamber with a slag collection container that follows in the direction of gravity are provided within a pressure container. This is achieved in that, in addition to a device (14, 15) forming a water film (16) in the quench chamber (11), at least a part of the cylinder forming the quench chamber wall (17) is designed with a double wall and with a coolant overflow (21) for additionally wetting (18) the inner surface of the quench chamber wall (17), and a tangential coolant supply (20) in the bottom area of the double walled cylinder (19) which is closed at the bottom.